LOCUS       DACDLM010000001        89192 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.001, whole genome shotgun sequence.
ACCESSION   DACDLM010000001 DACDLM010000000
VERSION     DACDLM010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 89192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 89192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..89192
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.001"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(281..433)
                     /locus_tag="IV356_000001"
     CDS             complement(281..433)
                     /locus_tag="IV356_000001"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013732.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
     gene            complement(624..1502)
                     /locus_tag="IV356_000002"
     CDS             complement(624..1502)
                     /locus_tag="IV356_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP9013733.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(1541..2659)
                     /locus_tag="IV356_000003"
     CDS             complement(1541..2659)
                     /locus_tag="IV356_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HAP9013734.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(2656..4755)
                     /locus_tag="IV356_000004"
     CDS             complement(2656..4755)
                     /locus_tag="IV356_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HAP9013735.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(4806..5627)
                     /locus_tag="IV356_000005"
     CDS             complement(4806..5627)
                     /locus_tag="IV356_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP9013736.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(5624..6433)
                     /locus_tag="IV356_000006"
     CDS             complement(5624..6433)
                     /locus_tag="IV356_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP9013737.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(6454..6948)
                     /locus_tag="IV356_000007"
     CDS             complement(6454..6948)
                     /locus_tag="IV356_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP9013738.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(6960..7448)
                     /locus_tag="IV356_000008"
     CDS             complement(6960..7448)
                     /locus_tag="IV356_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP9013739.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            complement(7525..10221)
                     /locus_tag="IV356_000009"
     CDS             complement(7525..10221)
                     /locus_tag="IV356_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP9013740.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(10649..11722)
                     /locus_tag="IV356_000010"
     CDS             complement(10649..11722)
                     /locus_tag="IV356_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP9013741.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(11719..12546)
                     /locus_tag="IV356_000011"
     CDS             complement(11719..12546)
                     /locus_tag="IV356_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9013742.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(12547..13353)
                     /locus_tag="IV356_000012"
     CDS             complement(12547..13353)
                     /locus_tag="IV356_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9013743.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(13365..14450)
                     /locus_tag="IV356_000013"
     CDS             complement(13365..14450)
                     /locus_tag="IV356_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9013744.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(14467..15009)
                     /locus_tag="IV356_000014"
     CDS             complement(14467..15009)
                     /locus_tag="IV356_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP9013745.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            15267..16256
                     /locus_tag="IV356_000015"
     CDS             15267..16256
                     /locus_tag="IV356_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HAP9013746.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            16253..16990
                     /locus_tag="IV356_000016"
     CDS             16253..16990
                     /locus_tag="IV356_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HAP9013747.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNCLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEETQSKSEIAALITEKIRLEESK"
     gene            16987..17538
                     /gene="coaC"
                     /locus_tag="IV356_000017"
     CDS             16987..17538
                     /gene="coaC"
                     /locus_tag="IV356_000017"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HAP9013748.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            17554..18186
                     /locus_tag="IV356_000018"
     CDS             17554..18186
                     /locus_tag="IV356_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP9013749.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            18271..18918
                     /locus_tag="IV356_000019"
     CDS             18271..18918
                     /locus_tag="IV356_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP9013750.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            18923..19906
                     /locus_tag="IV356_000020"
     CDS             18923..19906
                     /locus_tag="IV356_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HAP9013751.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMKANKNIGKIILKITE"
     gene            complement(20309..21823)
                     /locus_tag="IV356_000021"
     CDS             complement(20309..21823)
                     /locus_tag="IV356_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HAP9013752.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            21961..22767
                     /locus_tag="IV356_000022"
     CDS             21961..22767
                     /locus_tag="IV356_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013753.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(22942..23511)
                     /locus_tag="IV356_000023"
     CDS             complement(22942..23511)
                     /locus_tag="IV356_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP9013754.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(23594..25656)
                     /locus_tag="IV356_000024"
                     /pseudo
     CDS             complement(23594..25656)
                     /locus_tag="IV356_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(25933..27411)
                     /locus_tag="IV356_000025"
     CDS             complement(25933..27411)
                     /locus_tag="IV356_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAP9013755.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(27709..28644)
                     /gene="murB"
                     /locus_tag="IV356_000026"
     CDS             complement(27709..28644)
                     /gene="murB"
                     /locus_tag="IV356_000026"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HAP9013756.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(28717..29637)
                     /locus_tag="IV356_000027"
     CDS             complement(28717..29637)
                     /locus_tag="IV356_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP9013757.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            29750..30502
                     /gene="xth"
                     /locus_tag="IV356_000028"
     CDS             29750..30502
                     /gene="xth"
                     /locus_tag="IV356_000028"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HAP9013758.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            31488..32021
                     /locus_tag="IV356_000029"
     CDS             31488..32021
                     /locus_tag="IV356_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HAP9013759.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(32511..33035)
                     /locus_tag="IV356_000030"
     CDS             complement(32511..33035)
                     /locus_tag="IV356_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP9013760.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(33028..33501)
                     /gene="tsaE"
                     /locus_tag="IV356_000031"
     CDS             complement(33028..33501)
                     /gene="tsaE"
                     /locus_tag="IV356_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HAP9013761.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(33624..34604)
                     /gene="pta"
                     /locus_tag="IV356_000032"
     CDS             complement(33624..34604)
                     /gene="pta"
                     /locus_tag="IV356_000032"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HAP9013762.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(34757..35437)
                     /locus_tag="IV356_000033"
     CDS             complement(34757..35437)
                     /locus_tag="IV356_000033"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAP9013763.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            35563..36432
                     /locus_tag="IV356_000034"
     CDS             35563..36432
                     /locus_tag="IV356_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP9013764.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            36458..36973
                     /locus_tag="IV356_000035"
     CDS             36458..36973
                     /locus_tag="IV356_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013765.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(37020..37583)
                     /locus_tag="IV356_000036"
     CDS             complement(37020..37583)
                     /locus_tag="IV356_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP9013766.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(37638..37817)
                     /locus_tag="IV356_000037"
     CDS             complement(37638..37817)
                     /locus_tag="IV356_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013767.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(37894..38403)
                     /locus_tag="IV356_000038"
     CDS             complement(37894..38403)
                     /locus_tag="IV356_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013768.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(38499..38879)
                     /locus_tag="IV356_000039"
     CDS             complement(38499..38879)
                     /locus_tag="IV356_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAP9013769.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            39209..39958
                     /locus_tag="IV356_000040"
     CDS             39209..39958
                     /locus_tag="IV356_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HAP9013770.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(40142..41419)
                     /locus_tag="IV356_000041"
     CDS             complement(40142..41419)
                     /locus_tag="IV356_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013771.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(41498..42142)
                     /gene="pcp"
                     /locus_tag="IV356_000042"
     CDS             complement(41498..42142)
                     /gene="pcp"
                     /locus_tag="IV356_000042"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HAP9013772.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(42341..43285)
                     /locus_tag="IV356_000043"
     CDS             complement(42341..43285)
                     /locus_tag="IV356_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HAP9013773.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(43287..43973)
                     /locus_tag="IV356_000044"
     CDS             complement(43287..43973)
                     /locus_tag="IV356_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HAP9013774.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            44447..44767
                     /locus_tag="IV356_000045"
     CDS             44447..44767
                     /locus_tag="IV356_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HAP9013775.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            44921..45826
                     /locus_tag="IV356_000046"
     CDS             44921..45826
                     /locus_tag="IV356_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP9013776.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            45823..46596
                     /locus_tag="IV356_000047"
     CDS             45823..46596
                     /locus_tag="IV356_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP9013777.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(46777..48201)
                     /locus_tag="IV356_000048"
     CDS             complement(46777..48201)
                     /locus_tag="IV356_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP9013778.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            48412..48858
                     /gene="nrdI"
                     /locus_tag="IV356_000049"
     CDS             48412..48858
                     /gene="nrdI"
                     /locus_tag="IV356_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HAP9013779.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(48923..50905)
                     /locus_tag="IV356_000050"
     CDS             complement(48923..50905)
                     /locus_tag="IV356_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP9013780.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(50919..51815)
                     /gene="murQ"
                     /locus_tag="IV356_000051"
     CDS             complement(50919..51815)
                     /gene="murQ"
                     /locus_tag="IV356_000051"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAP9013781.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(51818..52879)
                     /locus_tag="IV356_000052"
     CDS             complement(51818..52879)
                     /locus_tag="IV356_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAP9013782.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(53090..53617)
                     /locus_tag="IV356_000053"
     CDS             complement(53090..53617)
                     /locus_tag="IV356_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAP9013783.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            complement(53684..55186)
                     /locus_tag="IV356_000054"
     CDS             complement(53684..55186)
                     /locus_tag="IV356_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HAP9013784.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(55444..56565)
                     /locus_tag="IV356_000055"
     CDS             complement(55444..56565)
                     /locus_tag="IV356_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAP9013785.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYSLGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            56691..57632
                     /locus_tag="IV356_000056"
     CDS             56691..57632
                     /locus_tag="IV356_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAP9013786.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(57782..58678)
                     /locus_tag="IV356_000057"
     CDS             complement(57782..58678)
                     /locus_tag="IV356_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HAP9013787.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            58947..60287
                     /locus_tag="IV356_000058"
     CDS             58947..60287
                     /locus_tag="IV356_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP9013788.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            60505..60948
                     /locus_tag="IV356_000059"
     CDS             60505..60948
                     /locus_tag="IV356_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HAP9013789.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(61452..62870)
                     /gene="nhaC"
                     /locus_tag="IV356_000060"
     CDS             complement(61452..62870)
                     /gene="nhaC"
                     /locus_tag="IV356_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAP9013790.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(63273..64496)
                     /locus_tag="IV356_000061"
     CDS             complement(63273..64496)
                     /locus_tag="IV356_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HAP9013791.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(64527..65366)
                     /locus_tag="IV356_000062"
     CDS             complement(64527..65366)
                     /locus_tag="IV356_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HAP9013792.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(65383..66063)
                     /locus_tag="IV356_000063"
     CDS             complement(65383..66063)
                     /locus_tag="IV356_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9013793.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(66065..67138)
                     /locus_tag="IV356_000064"
     CDS             complement(66065..67138)
                     /locus_tag="IV356_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP9013794.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     gene            complement(67785..68456)
                     /locus_tag="IV356_000065"
     CDS             complement(67785..68456)
                     /locus_tag="IV356_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP9013795.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(68543..71221)
                     /gene="mgtA"
                     /locus_tag="IV356_000066"
     CDS             complement(68543..71221)
                     /gene="mgtA"
                     /locus_tag="IV356_000066"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HAP9013796.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCGDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            71880..72317
                     /gene="ndk"
                     /locus_tag="IV356_000067"
     CDS             71880..72317
                     /gene="ndk"
                     /locus_tag="IV356_000067"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HAP9013797.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(72339..73205)
                     /locus_tag="IV356_000068"
     CDS             complement(72339..73205)
                     /locus_tag="IV356_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP9013798.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(73365..75458)
                     /locus_tag="IV356_000069"
     CDS             complement(73365..75458)
                     /locus_tag="IV356_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAP9013799.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(76207..76830)
                     /locus_tag="IV356_000070"
     CDS             complement(76207..76830)
                     /locus_tag="IV356_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013800.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(76989..78386)
                     /locus_tag="IV356_000071"
     CDS             complement(76989..78386)
                     /locus_tag="IV356_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP9013801.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(78418..79389)
                     /locus_tag="IV356_000072"
     CDS             complement(78418..79389)
                     /locus_tag="IV356_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP9013802.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            79763..80188
                     /locus_tag="IV356_000073"
     CDS             79763..80188
                     /locus_tag="IV356_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013803.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            complement(80676..81377)
                     /locus_tag="IV356_000074"
     CDS             complement(80676..81377)
                     /locus_tag="IV356_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAP9013804.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(81393..81833)
                     /locus_tag="IV356_000075"
     CDS             complement(81393..81833)
                     /locus_tag="IV356_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HAP9013805.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(81833..82408)
                     /locus_tag="IV356_000076"
     CDS             complement(81833..82408)
                     /locus_tag="IV356_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HAP9013806.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            complement(83256..83735)
                     /locus_tag="IV356_000077"
                     /pseudo
     CDS             complement(83256..83735)
                     /locus_tag="IV356_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015510350.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(83894..84595)
                     /locus_tag="IV356_000078"
     CDS             complement(83894..84595)
                     /locus_tag="IV356_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP9013807.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(84703..86112)
                     /locus_tag="IV356_000079"
     CDS             complement(84703..86112)
                     /locus_tag="IV356_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HAP9013808.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            complement(86160..88025)
                     /locus_tag="IV356_000080"
     CDS             complement(86160..88025)
                     /locus_tag="IV356_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP9013809.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(88146..88997)
                     /locus_tag="IV356_000081"
     CDS             complement(88146..88997)
                     /locus_tag="IV356_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP9013810.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
BASE COUNT        26091 a        18654 c        15441 g        29006 t
ORIGIN      
        1 aaaataaaaa atttattgca aaaaaaatag aagtgacaaa attatcaatc atttcaaggt
       61 aatataacta cctgagttta ttatcgatta aaatgctaac tacatttgca agagaagcga
      121 gagttaaagg taaatataga atttctactt ttttagcaat agaaatagga ataaaatatt
      181 taaaatgtat agaaactttc ttttttttct tgctatcttt ttataatcac aactctctat
      241 aatagaatta cgatttattt tatacggctg aaaaaatcta tcaccaaaaa aattcaaaca
      301 ttaagccaag gattatgaag tcaacatttc gaaaaatgaa catacattgg taagcaacta
      361 taactattac cacagacata aagtaacaca atatattact atttaagtgt acgccaccag
      421 tgaatatcct caaggtatac agcgcacaac aaaaagaaaa aaggaaacgc agaagcattt
      481 cctttcagtg atttaatgaa aacaacacga tttgacttag agccttttta tttgaattca
      541 ttttcgcttt atccaacttc atttgatcat ttgattactc ggttaaatac ttttgacatg
      601 agtatcaatg aaacattcat taattatggt tgcttatttc ttaccgcttt tctggccaat
      661 gctaatccgc cgattattcc ggcattatca cctaattcgg gcgtaataat gtagctatca
      721 attggtggta tttcaacata tccatttata agctcaacaa atttatcctg aacttttttc
      781 ttcatgtgtt cttgtttcat tacaccaccg ccaaaaataa ttctatctgg cgaaaacatc
      841 agtgttgtat tgtatgcaca ttgggcaagg taaaaggctt caatctgcca aaacgaatcg
      901 tcagccaata aattctggcc ttttacaccc aaccgttttt caatcgctgg tcctgctgcc
      961 atcccctcta aacaatcttg gtggaaggga cagtttcctg aaaaattgtc ctttggatgt
     1021 cgcttgatca acatatgccc catttccgga tgactgaacc cttccacgaa agtcccattg
     1081 aacaaggcac cacctccgat acctgttccc acagtgaagt atgcaacacc tgctaaccct
     1141 ttgccagaac cagcaacata ttcaccatag caagccgcat tgacatctgt tgtccattca
     1201 atcggaatat tgaaatattg ctttagcgtt cctacaaaat tgaaattttg ccaagcaagt
     1261 tttggtgttg atgtgatatg accgaaactc gttgatttgc attgaatatc aattggacca
     1321 aagcagccga ccccgatgcc tgccaattgt tccttaaaag gtttaaaaaa atcaatgacc
     1381 tgcttcattg tttcaactgg agttgttgtg ggaaaactga ctctttccaa aatcgttaat
     1441 tcctcagtac cgactgcaca gacaaattta gtccctccag cttcaattgc cccatatatc
     1501 atcataggtt cctcccttcg aatatgtgaa aaacacttca ttaacgcggc aagcgttctc
     1561 gatcagtgaa atgacgttta gtatttcctg aagcttctgt tgaataccag taagcgacac
     1621 tagcaacatc gtcttgccgc tcaaataagc gaacatcatc gttgccgatt tgttgtaaag
     1681 tgaccgataa atcttcggta aaacagatgg ggtcttgaag atgccaacga taaagaccat
     1741 gtcgtggcat tgcgtcgtca ccaaaggcat gaacggcatt caattttccc gtttcaaaac
     1801 gatctcttgt ggcatctcta tttgattggt aaggataccc taaaaaggct gttgaatagt
     1861 ttttcgcatg tggacgtccg aactcatcgt actcatgaaa ggcccacgcc ccgccaaaat
     1921 aatcttctga acctgttgag gttacggtcg gatactcact atccccatca atgtagaatt
     1981 taaactcgcc ttcgccccac caataacgtt ctaggcaggt aagcgcaagg taagtaccca
     2041 cgtaatagcc ttgacccttt aatcgatcaa ttaacttata atcctcctgt aatttggtaa
     2101 tgcgttcccg atgccaattt gcgtgaaaat ataggctatt ttcttccaat tcgtccacca
     2161 aagcgtaatt tatcgtataa aaaaatgagg acatatcctt cggatgtaaa ttctcgatcg
     2221 taattttagc ggatgtttgg aaaggcattt cgaaatagga attaaagccc cctgtaggat
     2281 taaccactat cggcaacgag ttcacctcgc aacgctctcc aaacccatta caaaagaaat
     2341 cccctaaagg actttcaaca gcagggctat ccgacccatc ccaataaatt cttaagatta
     2401 aatcacgtaa aacaaaactg ccaaattctg ttcgatcacg aatcgtcatc cacatatgac
     2461 gaattattcc cgttccagta atatccgcaa tcacagtttc ttcaccagaa gtcagcggaa
     2521 ttgcgccacg acctttgcgg cttggtccta gctcgcttgg caacatcgca gctttacctt
     2581 tctcgcctgt tggattttcg ggagtgattg ctcgactctg gattttttta aattgggtaa
     2641 tattttttag tatactcatc tttttctcct ttgaatgtga atcgtttttc ccttttctac
     2701 gtgaagaatt tttttcgtat cacttatttt caatggcttt tctgacaaat ttgaaatact
     2761 caactcggat tgcgtacatt caatcgaaat gaaggcttga ccgaacttca aattcttcca
     2821 agaaaacgtt aaattatcaa caggatcaat ttgcaatact ccttttttga atttcaatcc
     2881 gaaatattga ctgatcatta ggctgacaaa aagacccgat gcccagccgc atttgccgca
     2941 gccaaagtct cgcacgactt ctccttgttg agcctctaag cgatacggcc accaccacca
     3001 cgaaccgtct aaatctgcca aacaaattag ttcttctaat cgggttacga aagcttgagg
     3061 gttgtgaagc tcgctcatta aaacagtgat aaagccagga aaagtggcgc cggattctaa
     3121 tccccaagtg atgcctttga tttcctcgct ataggttgga ttgaaagaac tagcagaaaa
     3181 ggccatggtg ttctgatata aatgatcttt attatctaaa aattgataaa aaggcatcaa
     3241 cgtagtgtct gattcttctc catcatgcat caataaatta atttttccat ccacaatcac
     3301 atcacttaaa aagattaacc cttgctcaag aatcggtttt tgatagtgct tcactgaata
     3361 ggttgttttc tcctcatcac cgattccctc caaaaattgc tcaccaaaag gaccatcgat
     3421 agtcatttgt ttacaaattg attcctttag tttacaggca atgtttttgt atcgcttgct
     3481 aagactcagt tgttctaggg cttcaaaaat ttctgcaagt ccaatacagg ccttccaaag
     3541 acaaagattg ctgccggtat gatactttcc aagtgcaaag gcgtctgata accaaacaga
     3601 tggaaaaagc attggttccc ctgaccgacg ttgagctaat atgtcctcaa taattcttga
     3661 agcattcagt agaacctgcg gacaccgctc aaagaatttt gtatccccag tatgttcaaa
     3721 ataaagacta gccagtaacg cactggataa cgaattactc agagaatgat tgatacctcc
     3781 tgtaaatttt gaaccaggaa acttaacgcc atattgatca aaccatagaa ccgttttttg
     3841 acataactcc ggttcaaaca tggtgaatgg caatgatgcg taatacatat ccttattcca
     3901 aattcgatta gtagcaggat agctgcccca attgctgccg acgacctgtc cctgtcgatt
     3961 cataccgaaa ctagaaaagc tttgataaag tgcacgacga tagagatgga caactctatc
     4021 gtttggcatt gacagctgcc caaatagctg agcaaaatag ttcaatgttt ccttcagcca
     4081 tttttcgata tcagattcct gaaaagtcat tacttcttca aaagcatttg ggtccacaaa
     4141 agcaatggcg aagcttgcca cttcctgttg tgcgatcgtg tccttatttc ctttttgaga
     4201 aatcaacaca ttttgctgat ccgaatactt ctcttgatac gaaggcacat ctttcactga
     4261 aacttgaagg ctttcgtgtg tttcattcac aatgtaaacc tgttgaacaa gcatacttaa
     4321 acgcttatta gccagtatgg gagcaaagga tactacaatg accttaaacg tcgaataatg
     4381 atgaatatat ctaggcaaac agtcttgaat cacatcgact tcaatacgat gatccgattc
     4441 tgacaaatgg tagacaatcc cgtttacttc aacctttaag gataacgaat tggtttgaga
     4501 gagctgttta ttgacccaaa cacctggttt ttcctcagtt agtaaatttt ctcgataaaa
     4561 ggtcaacgtt tgaatcgtcc cgcaaacatc aaggtttgct aatgtctttt gattacttac
     4621 atcgaaggtc aatcccttta catcaggaat attccgatag tagctgtatt cgtttgaagt
     4681 agtcacattt ccgtcgttta actcagcatt aaaaaatggg tgtttgggtg aataaattac
     4741 ttcattaata gtcatctttt ccctccttgc taaaaaaact gcagcctagt agctgcagct
     4801 tcctactatg cgattccaag taatgacaat aaaattccca agacgaccat tccaaaaata
     4861 attttgatga cgccgacttt tttatctagt aatttgaaac agctcaatgt taccaataac
     4921 ggtacaattc ctttaaaaat actatcgagg atttcttgga cattcattag ttcttcgccc
     4981 ttcattgaaa agctcaaaac ggtattgaat ttgaccatac tgatcgtcat tgcacctacc
     5041 atgatcagac ccaagatact agcagctttt gtcagaattt caattaaccc gttcgcatac
     5101 agcttttcaa tatatttaga gcctaatgaa tagcctaaaa cgccgccata gtatcgcatc
     5161 aagtaattag gtatattgaa cataactaaa aagataattg gtgccaaaat atttccggca
     5221 ttggctaagt tgatcgctag tcccgcggta acgacacgcc aaactcccca gaacaatgaa
     5281 tcgccaattc cagccaatgg tcccatcaaa ctcgttttga tcgcgttgat actttccacg
     5341 tcaaaaccag ctttttcaga attttccttc tccatcgatg ccgcaatccc catgacaaag
     5401 gacgcgcaag gaatggtcgt cgaaaaatac tgtgtatgac gttccagcgc cgcagctcga
     5461 tcttcttcac ttttgtagaa atgattaatg aagggcatca tagaataggc gaaaccaccg
     5521 ccgcccatcg tcaccggatt caccgaagca tacatagtca tcgagcgcca aaacatcttc
     5581 cgaaccaatt ttttctcatc tttagaaatt ccatcagcta atttcattga aagaaatcct
     5641 cctcttcttg gtcaagcgtt gcatttacag cagcatcgct ttgaactgca tgaacagata
     5701 tattttttag ttgtagatct ctttgggcta taacaattgc aataatcgtt ccaactgcgg
     5761 caattgcaat caatggtaac tcgagatacg ccataacaac ggccccaaag aaaaaccaca
     5821 cagcaatatt tttactccaa agcatccgta acagcatcgc catcccaact gccggcagca
     5881 gatttccagc gactgttaat ccgttcatga tgacctctgg aatattatcc aagacgcttt
     5941 tgacaacatc tgctccaaat aaaacggcaa agaatggaat aagagcataa agcgcatagt
     6001 ggacaaacca cataaagaag tgcagattga tgattccttt ttgatcacca gattttgcaa
     6061 atttgaaaaa tttagcagcc atcggtccac atacaaaaga aaaaatcata ttcattaact
     6121 gtaatcctaa tactgctagt ggaaagacaa tgggaataat cgcatccacg tttcctccca
     6181 ttttgattgc gaacgctgta gccagcccag cagccaaaga aggctccgcc gtactagaga
     6241 ttccgatatt gacgacaccc ataaagatgg cttctagtga cgccccgaca atcaaccccg
     6301 tctgcaaatc ccccatcaac gctcctgcta acggagcaac aacaatcgga cgactcagca
     6361 tggacatccc gaacatttca tgtccagcaa ctccaataaa aacggccaaa gcgactacaa
     6421 atgcatcata cataattttt ctccttcctt tttctaaaaa tcactcaaaa tagagatagc
     6481 tgaacgtttt tccatcgccg gtgtaggctg aaaaacggta tctggataaa gttcaactaa
     6541 ttcttttaag tcttgaattt ctgacgtcgt taacatcact tcctttgata aggttttctt
     6601 atcttccgat ggcggtgtca ttttcccagc attccccacg ttcattaatt cgatttccgt
     6661 tgggaaagct ttcgcaactt ttaccgcatc tttgacatta gggactaaaa ccatcaagcg
     6721 catgtccttc gcccgcggat cttttaacaa atgaatcgcg tcatcaactg ttttaataat
     6781 gactttgaca ttcgatggtg cagccatctt caatgtcatc ttttgaatat cgttggtagc
     6841 cgcctcatcg cttgctacta ctaacccggt taaatttaga ctctttgtcc aagtcatcgc
     6901 tacttgtcca tgaattaatc gttcatcaat tcgcactgct ttaatcattt ttcttcctcc
     6961 taaaaaaaat cttcctcttc atttactaca tgtacctcat caagaatggt catctttaat
     7021 tcctgttggc atttatttac cagttcctga atatcctcct ttgttaattc cttggttgcc
     7081 aatactattt cgagcagaat tggcagatta aagccagaca aaatagttac agcaatctct
     7141 ttctccaaaa aggttttggt aatcttctga ttgacacttc cgccaaataa atcggtaaaa
     7201 acaaaaatct gatcctgctc gttcacctgg tttacaaata cattcaactc ctgttcaaaa
     7261 tcacactcat ccacataagc attaatcacc gtaatctctt gaaccttccc cgtcagtaat
     7321 tgaatactgc taagaaagcc tgaagctaag tgaccgtgag tcgctattag aattttcttc
     7381 atatggttaa ttcctttctt tctgttcact tttatataag caattcctgt gccaactttt
     7441 aaaaacattg gtttaatcac gttaattcac attaaaaaaa gtgtctaacc taaaaaaaac
     7501 agattagaca cttttttaga cactttattt ttgaatatac ggtcctaata attcatagag
     7561 cagcgaaagc tcataagcat tgactttaaa attatatttc atctccattg attgaaaaat
     7621 acttctagaa acataataaa attcatcttc atctggtttc aaatcataat tcggttcttc
     7681 agatttttct gtccgagcca agaataaacg ttccatcatc aatgccgtat gcatatagag
     7741 atttagtttt acacggccat ttaaagtgaa atgatagtaa ttttcatatt tagaaatgac
     7801 tgtttccact tcactcatca cgatcgttgg gttcagaaag ttcaaacggt ccgcaattcc
     7861 ttccaacgaa aagaatttta ctagctcctg aatcaagcgg ttaaattctg ccggcttcat
     7921 ttcaggactc aaaatatgct ccaaattggc tgctccatca ccgtctaaga tgtcataaac
     7981 attaatatta ggaattgaaa aggaacgtgg aagatccgaa gtcgtgatga ccaattttgt
     8041 cttgtcaaaa taagtttcat cattttggtc gattaattca cgtagttctc tgtagtcctt
     8101 cgtgaaaact tcgatggatt catccgataa atgatgacga aaaacatctt tcaatttgtc
     8161 cgaaatcccc aaacccgaca tacaggaaat gataatgttg ctactttgag aaaagccttc
     8221 aaagtattga acattgattg aatacttgtc tgctgcatcc tccgcaatct gtttaaatgg
     8281 cgcattcatc gtcatcttca agccaatatc aagtgcaatg gaagtcgtca aattattcag
     8341 aagaagtaac tcccctttta aatcgttctt gatctgtgtg taaatttgat ttaaagagcc
     8401 catatctacg atcagcacta gactatctgt attcacttgc cgtttcacga aattccttgt
     8461 cgattcgaca atctctgaca cattactctc tactggcata tccaacgctt caaaaacata
     8521 attgccgcat aattgattca ctactgcttg aatgctgcta gccgtactat ctccgtgagc
     8581 aagcaacagg cccttcagct cgatggattc atctacataa tcagataaag tcacgacaat
     8641 aagcagtctt agaaagttct cgtccttttc tgagagcggt ggtaaatgct ccaagaactg
     8701 attacataag taagtcgtcc gaggtagatt tgcagctaat gtacgattta tcccggttaa
     8761 gtctgtctta tagcttgggg aaatgacata ggatctgcta ataatttctg caacaggtcc
     8821 actcgtcgtc aatccgtacg tttttcctaa aacggatacc cagacctttc taaacatctg
     8881 aatcatcaat tttctactca ttgataaaaa agaatcctta tcaatgtgat gcaccaaatg
     8941 ctgtacttca ttctttatcg aagaaaaatt ttcattgaaa ttaccttcat ttatcagctg
     9001 agtaattttt tccaaaatcg aatcataatc aaacggtttg attcgatccg tttttatctt
     9061 ttgatttttc tttatcaata aactagcaat cggcaagctt tctacttcgg attccagcat
     9121 atttaactga atcaagatct catttttccc aatcgttaat ggttcttctt gtgttcgact
     9181 atacacatcc gcacaactga ttttaatgat attcttcagc ttaccaatat tcccactaaa
     9241 gggatgagat aacattaaag acaaggcttc tcttgaaaca ataatatctt tttgtaaaac
     9301 atccgcttca ttttgaaaaa ataattgaat cagctctaat cgttctcgaa tggggcgatc
     9361 ttcaaaagtt ggcaacataa cactaatttg aatacgccga tcaaaggtgt ctaataaata
     9421 attttcacct ttttccgtcg tggcgaaaat aaaacgaacc ttagcagaat gccaatttac
     9481 attttcaccg actggacgat agtttccagt atcaataaat agaaagagct tttcttgatt
     9541 ttctttcgat aggcgatgga cctcatcgag aaaaagatag ccgttgttgg ccgttgccaa
     9601 taaaccatcg gtatcctttt cagcccccgt aaaggccccc ttcttgtatc caaacagtgt
     9661 tgccgaaagc agttcgggat tgtccgcata atcggcacag tttaagatag caaatggtgc
     9721 atctttttca ataatttgct catggatagc gtattcaaaa atttttgtgg ctaaaaaact
     9781 ttttccaaca cccgtggctc catttattaa tacactgagt ccgttaggcg gatatttgac
     9841 agcggctata catttttgaa tgacctctct cagacttccg tcatgaccaa ctacagaatg
     9901 aaaggcttcg tttatttgct ccgtattatc tacaaccgca tattcatcta aaggcttcca
     9961 caaaacaggc tttcccggta atttctcgac ctttttatct tccactaatc tcgtcaaata
    10021 atggctggca ttctgacgag agatacctag attcttcgaa attttctcgg cagtgacaga
    10081 agacatattc cctgttagtc gtatcagctc atcaaaaact cgatctttag cgctcttttt
    10141 cattttttcc tccagtttaa tgtgtctaaa agcataataa actatcggct gcaatatgtc
    10201 tattctatat ttgtattcca atttttactt tgaaacacaa atagtcgaat atttgcctca
    10261 gatatctgac aaaataattt atctaccaat ttagttttta tctaatatga tttttatgtt
    10321 ttttcatagc tacaaatatt gaactggatt catatattag ttttattaat agattacaga
    10381 agggttaagt atatttgcat agtttccaat tactttatcc ttctgtaact ttttcaatct
    10441 tagatttact agcccgtctc gggccctatt ttacaatggt tttgtccact tttctctggt
    10501 agaaaaacgt ggtagaaaaa ataaaataac acaaaaaaag cggcgtttca tccgcttttg
    10561 gtagaagatt ggaaaactca gatagaaaaa ggacgatttt tagctcttta gaacgttgat
    10621 aagtccccat tcttactgag ttttgccatt atctcctata catcttgaat tctaagaata
    10681 ggtcattata gatgcctagg tatttcgatc ctagatcttt gtagacttca agatgggaga
    10741 tcgtgtcatc agatggatag aattgttcgt ccgacgaaat gtcttttggc aataacgctt
    10801 ttgcttcttc atttggtgta gaataaccaa tatactctgc attttgtgcc gcattttccg
    10861 gttctagcat aaagttgatg aaatcatagg caccttcttt atttttcacg gtttttggca
    10921 taacgatatt atcaaaccaa agattggatc cttctggtgg gatcacataa tgtaaatgtt
    10981 cattttccca catcatatcg gcagcttcgc cagaaaatgt cactgccacg gaggcttctt
    11041 cattgatcat atacattttg atctcatctg ccacgattgc tttgacattt ggtgttaaat
    11101 gattcaattt atttgctgct tctgtcagct gtgccatatt cttactattc aaagaatagc
    11161 ctaaactatt caaagaaagc cccataactt ctcgtgcacc gtcaatcagc atcaaactgt
    11221 cttttaattc cggcttccac aaatcatccc aatgcttaat ttgatttgca tcaaagaatt
    11281 tatcgttata tacgatccct aaagttcccc aaaaatatgg aatcgaatac tgattatctg
    11341 gatcaaaatc caagtctaaa aatcgtggat caatattatt taatcctttg atcttcgaat
    11401 gatctaatgg aagtactagt ttttctttga tcattttttg gatcatatat tcacttggta
    11461 tagcgatgtc gtagtttgtc ccaccttgct ggatttttgt gaacatcgct tcattagaat
    11521 caaatgtttc ataattcact ttgtatccat attctttttc aaatttcgtg atcaaactag
    11581 gatcgatata atctccccag ttatagatgg taagtacctt tgctccactc atgccacttg
    11641 ttttttcaag ttgacgaaca ccaagcagca gcaccgcaat aatgatgaga atacctaaaa
    11701 acagagattg taattttttc atcgcagccg tgccaccccc tcgcgtactc ttctgttttt
    11761 cttcagccgt tttggacggt tttctttact aataaagtag tatccaatga ccaatatcat
    11821 ggagaacaag aaaactaacg cacttagcgc attgatttct aaactgattc cttgtcttgc
    11881 acgagaatag atctctactg agagcgtcgt aaagccattt cctgtgacga aaaatgtaac
    11941 cgcaaaatca tcaagagaat aggtaaatgc cataaaatat ccagctatga ttcctggaga
    12001 aagataaggc aaaatgatat ttttgactac ttggaaatta ttagcaccaa ggtctctagc
    12061 cgcatcgacc attgaatcgt tcatttcctg caattttggc aagaccatca agacgacgat
    12121 tggaatgctg aaagcaatat gggaaagcaa tacactctga aaacctaatc cgaatcctag
    12181 tagtgtaaag aaaatcaaga aactagcacc gataataaca tcaggagaga ctaataagat
    12241 gttattcatg ctcaacaacg ctgtccgtgc acgtcgtttt ttcgtgtaat agattcccat
    12301 agccccaaat gtcccgatga tcgtggcgat caatgcagat aagaaagcca gcatgaacgt
    12361 attcaatacg ataatgatca aacgtgtatc ttcaaaaaca gcttcataat tttcccaagt
    12421 aaatcctgta aagctgttca tcgttcctcc ttcattgaag gaataaaaaa tcagatagaa
    12481 gatcggtgca tataagaata aaaagacgat ccctaaataa agatacgacc atttaaattt
    12541 tttcatttat gagcgacctc cttttttctt ctcgcctgtc aggagcatca cgatgaacat
    12601 agcaatgatt aaaatcacac cgattgtaga acccatcccc cagttttgtg taaccaagaa
    12661 atgctgttcg atagccgttc ctaaagtgat cacccgattt ccgccaatca gacgagtcag
    12721 catgaataaa gaaagagaag gaataaatac tgcttggaca ccacttttca caccatttaa
    12781 tgataacgga aaaatcactc gtcggaaggt ctcaaagcta ttcgcgccta aatctctact
    12841 agcactgatc aaagaaggat tcatctcttc caatgcattg aaaattggca taatcataaa
    12901 tggaatctcg atatacgttg ccacgaacag aaaactgaag tctgtgaata atatctgttt
    12961 cggcccgatc ccgataaaat caaagaaatg attcacgctg ccgtgcacac tgaaaatccc
    13021 aataaatgcg taagctttaa gcagcagatt cacccatgta ggcaaaataa tcagcatcag
    13081 ccataattgc ttgtgcttca gttttgttaa aaaataagca gtcgggtaac tgatgatcag
    13141 cgtgaaaaac gtgatcaaaa atgcatacca tacagaattg atcgtcatag aaagcgatgt
    13201 ccccgacgta aaataagata gataattatt cagcgtgaat tgcccattca tatcaaaaaa
    13261 agattgataa atgatcatta atacaggcgc gatcacgaat aaaccgagcc acaaaatata
    13321 agggacggaa tagatcctgc gcattgtttt cattcttgtc ccccctattc ttcgtagctg
    13381 tcaagacgtg catcgaattc ttcttcagac tcgttgaaac gcatgacatg gatatcttct
    13441 ggctcaaagg ccaatcctac tttgcttcct tctttagctt ttttcgttga atggaccatc
    13501 cattcatttt gctgttcatc ataacagatg atttcataat ggacaccacg aaacagctga
    13561 gtatcgaccg ttacgactag ttttccttta tctggtgtcg tgatcgtcaa atcctctggg
    13621 cgtaaaacaa cttcaactgg ttcatttaga cgcatcccgc catcgacaca ttcaaattgc
    13681 ttaccaacaa actcaactag attatcttcg atcattacac cgtccacgat attgctctcc
    13741 ccaacaaaat cagcaacgaa atgattgatt ggctcatcat aaatatctac gggtgtacca
    13801 ctttggacga ttttcccttt attcatgaca aaaatctcat cactcattgc caacgcttct
    13861 tcttggtcat gagtaacaaa aataaacgtg attcctaatc gttgttgcag atcccgcagt
    13921 tcatactgca tatctgtacg tagtttcaaa tcaagcgccg ataacggttc atctaatagc
    13981 aatactttcg gttcatttac aattgctcgt gcaatcgcta cacgctgtct ttgaccacca
    14041 gacatttcac taatctcccg tttttcgtat ccaggaagct ggaccatacg caaagcatct
    14101 tttaccttct tttcgatatc tgatttggac attttcttga tcttcaatcc aaaagcaacg
    14161 ttatcaaaaa cattcatatg aggaaaaagt gcataatctt ggaagactgt atttacttgt
    14221 cgcttattag ctggcaaatc attcaaccgt ttcccttcaa aatagatgtc cccttctgta
    14281 gcttcggtga atccagctat aatacgtagg atcgttgttt taccacagcc ggaaggacca
    14341 agcagtgtat aaaattttcc ttgttcgatc tcaaaactta ctttttttaa tactgtttca
    14401 tcatcatagc gtttcactac ttgatcaaat gaaatgattg gtttccccac gtttttaccc
    14461 cctatattac aaatatgatt gcgttgcaac aatcaatact tttgttcgtt ttttgagatg
    14521 attccttaat tgatgttgtt ttgtcgcttg ataatagatc gactgtcctg cttttgccac
    14581 atagaccgtc tctcctaagc ttaactctaa ttccccttct aatacaaaaa taaacgtttc
    14641 agataatgaa ggttcaaacg tcttatattc tcctgcacct tcaaaagtca gcaagacagg
    14701 ctccatttct ttttcattcg aatcagccac gagccattcc aattcatacc cgttttcttc
    14761 atcgaaataa accgtatgat cttcttttga ataaaccact tgcagattcg ctgcttcttg
    14821 atgaaaaaat tcttctggag tcacacctaa gacttcaaga atagaaaaga atgtttccat
    14881 tgatggtgaa cttaaatctc gttccaactg ggaaatatac ccttttgaca aatctgtgcg
    14941 ttcgcctagt tcttcttgtg tcaaattctt ttggatgcgc aaatttctta acttctcacc
    15001 aatttccata atttcctccg aatcgaagtt ttctaatagt aaacttcctg tttactacca
    15061 ctcgtattag tatacgaaat ttattgaaaa aggcaaccct ttgtaaaatt ttttttgctg
    15121 aatatttctt tatcttttgg aataaattct agttgtttga ttctttattt ttcacctaat
    15181 ttttgtctaa atttacggaa gaacaagaat aaaagagtag gctttatggt atgataaaag
    15241 aaaattttaa aaggagtgtc tcacgaatga acgcttttcg atcttttcag gtaataaagg
    15301 aacctgtttt ccatacagca atcagtgatc tgccatttac tgagttggct gaaaatgaag
    15361 tcttggtaaa aattgcctat tctgatgtca attataaaga tgcattggca atgagcgagt
    15421 ctggtcaggt gatacgaaca tatccgatga ctccagggat tgatttatcc ggaactgtcg
    15481 tccaaagtaa caatccacgt ttttcaaaag aagatcttgt acttgctact ggttttgggc
    15541 ttggcgtcac ccatccaggc ggttatagcc aatatcaaaa agtaccagga gactggttag
    15601 ttcctctacc aaaaaatatg acgctgcgtc aagcgatgat ccttggtaca gcagggttta
    15661 ctgctatgtt gtgtgtgaac gctttaatcc gtcaaggtat gacctccgat aaaaaagttg
    15721 tcgttactgg tgcttctggc ggtgtaggca gtacagcgat agccctgtta cataaactag
    15781 gattccagtc aatcattgcc ttttccagaa aagaagagtc tgtcacatgg ctaaaaagtc
    15841 taggtgcttt gcaagtcgta cgacctgatg aatttctgcc agagacaaca aaagctttag
    15901 gaaaacagca aatcgactat gtcatcgaca cagtaggtgg cgagcagcta agcagtcttc
    15961 ttccattgat ctcttataac ggtgcagtag ctttatgtgg caatgctggg ggaatcaaac
    16021 taaacgcgac tgtcttgcct tttattctgc gaaacatcca gttgattgga attgattctg
    16081 tcaatgtacc aatagatcaa cgtctttctt tatggcaaca gatggcggat ttgcagattg
    16141 cagatgaact ggtcgtccaa gagattactc tggatcaatt gcctgaaaca gcatctaaac
    16201 tacttgctgg aacacaccaa ggaagaacac tagtaaatgt aggtgaccat aaatgaagat
    16261 tctaatcaca gctggaggaa cgactgaaaa aatcgatcaa gtacgtgcta ttacaaatca
    16321 ttcgacagga cgattagggc aagcattagc tgattattta gctgccaatc cggataccac
    16381 aatcgattac gtgactacga aacaagcact gaaaccgaaa agacactcca atataacgat
    16441 ttatacgatc gaatctgcac tggacttatt tttacaatta gaagaactaa cgaaaaaaga
    16501 acactacgat gcgattatcc acagtatggc agtcagtgat tttactcctg cttttagttt
    16561 ttcagaagaa cagctggcaa aaaacctacc cacttcttca acgcaagaag aactggacaa
    16621 ttggtttgcg gaaaatgaac agacagatac cactgtttca aagatctctt ctaacaccga
    16681 gcatcttgtg ctcgttttga agaaaacacc aaaaatcatt tcttatctac gtgaatggca
    16741 gccaaaagca aaaatcattg gtttcaaact attagtagat gtaccaaagg aatctcttct
    16801 ggcagtcgca aaaaattgtc tgataaataa caaaactgat tttattttcg caaatgattt
    16861 gacggaaatc catggcgaga cacaccacgg ctatctctta tctaaagatg gaacagtgga
    16921 agaaactcaa agtaaatctg agattgctgc attgattact gagaaaatta gactggagga
    16981 atcaaaatga aaaagatctt actaggcgtt actggaagta tttctgctta caaaagcgct
    17041 gatcttacaa gtcaattcgt caaattaggt gcccaggtag atgtgattat gtctaaaagc
    17101 agcacacatt ttatcacgcc attaaccttg caatctctgt cgaagcgcgc agtccataca
    17161 gacgtcatgc aagaatcaaa tccgcaggta atcaatcata tcgaactagc aaaacaagct
    17221 gacttgtttc tcatcgcgcc tgctacagca aacattatcg gcaagctagc aaacggcatt
    17281 gcagacgatc ttctttcaac agtcgcaatg gcgcttccag tgggaacacc aaaattgatt
    17341 gcccctgcca tgaacacgaa tatgtatcaa aacccgatca ctcagcgtaa tctggaaaca
    17401 ttgagatctg tcggctatca ggaaattgaa ccaagagaat ctcttttagc ttgtggagat
    17461 tttggaaaag gtgccttagc tgatattcag acgatcatcg aacaggtcat gctgactctt
    17521 aatgaaagaa atgcttagaa aaaaggagta cttatgaaaa atacaaaaaa ctttacatta
    17581 actgcgatgt ttttagctat tttgatttta ttagctgtta cgcctttagg ttttatccct
    17641 atcggtccaa tcaatgcaac aaccatgcat attcctgtaa tcattgcttc gatcgtttta
    17701 ggaccaagac taggtgcttt tcttggcggt acatttggac tgatcagcat gatccgtagc
    17761 acagttatcc aaacaccttt gtcttttgtc ttttctccgt ttatcccagt catcggaaca
    17821 gaacatggaa gctggaaagc cttgctgatc gcgtttattc ctcgcatctt gattggggtg
    17881 gttccttatt tcgtttataa aggtctgcgc aaactaatga aacaaaaagc agattccgtt
    17941 tctttattct tagctggact ttccggttca ttgaccaata cgattttagt gatgaatatg
    18001 atctactttt tattccagca agattatgcc aaagtcatcg gaacaaattt aaatgctgtt
    18061 tattcagcta ttctagcggt tatttttaca agtggtatac ctgaaggaat cgtcgcaggt
    18121 cttgcgactg cagcagtatg caatgtcttg ttaagatact tcaagcaccc ttctcttact
    18181 aactgatagt catcgtagcc gatctctgat ttttttctct tttggtgtta ctattgaatg
    18241 gaaagatttg acgtcgaaag gatgatccaa atgaaaattt ttgttgtagg tgcaaacgga
    18301 caaattggcc gacacctgat aaaagattta gctccaagtt cccatgaaat ttttgcaggg
    18361 gtgagagatg ttgcttccca aacattagta aaaaaagaga atgtttcgta tgtctctttt
    18421 gatttaactt ggtccgtgga aaaaatgacc gaagcattca aaggcatcga tgtattgatt
    18481 tttgctgccg gctctcaagg aaagaatctt ctgcaagtag acttggatgg cgcaatcaaa
    18541 acagtgatcg cagctgaaaa tgcgcatgtc tctcgctatc tgatggtcag tgctgtttat
    18601 gcagatgaac cagcaaaatg gcctgagtcc atgacagatt attatattac taaacattat
    18661 gcagatgaat ggctgaaacg aactaactta gattttgtca ttcttcaacc agtcacattg
    18721 actaacgatg aagaagttac ttccattcaa ttaactaagc ctaatgagaa ggcatcaaaa
    18781 acgatcactc gctctacagt tgctgctgta cttgccgctc tagtggaaga aacggatatt
    18841 tctcgtacga ctctagtact ttctgaaggt agcaaagagt tgaatacagc attccaagaa
    18901 tgggcaaagg aggaatagat ccatgcgtgc catttcaatc aagcatcctg gttctgtaga
    18961 tgtattagaa caaattgaag tgcctgttcc taaaccaaaa caaggcgaat tactgatcaa
    19021 agtccataca gcagctgtca atcgaacaga tattatgaaa agagaatcag tctctttgaa
    19081 acctccctac cctattttgg gagtcgaagt agctggagag gtagttgaga ataaaagtga
    19141 tatctccact tttactcctg ggacaaaagt atacggatta gtcaatctag gtggttatgc
    19201 cgaatatgct gtgatgcctg ccgatcgtgc aatccttctc cctgatacgc tagactatgt
    19261 ttctgctgct ggaatctcag aagttttttt gactgcttat caaacacttt actggcttgg
    19321 aaaattacaa gaaggcgaaa ctgtcttgat ccatgcagga gcaagtggtg tgggaacagc
    19381 agcgatccaa ttagctagac agctttctca cgcgaaaatc atcgttactg caggatcaga
    19441 agaaaaactc gccttttgta aagaacttgg tgcagatgaa ttgatcaact ataaaaaaca
    19501 agactttcaa gaagaggtac gaaaaatcac tgaaggtcgg ggagtcgatg ttattttgga
    19561 tttcatcggc gcttcttact gggaaaagaa tttagcttct atagccgttg atggacgttg
    19621 ggtcttgatt ggtatgctag gtgggaccat cgtgcctgag atagaccttg gtgtattgat
    19681 tgggaaacgt gtccaactgc ttggtacatt attgacacct agaagtgatc agtataaagc
    19741 agagctcgca caaactttta tgcaaaaagc tgggcctttt ctagaaaatg gcaagattcg
    19801 gccaatcatt gaccgtacat tccaattcag cgcagtcaaa caagcgcatg aatatatgaa
    19861 agcaaacaaa aacatcggaa aaatcatttt gaagataact gaataaaatc atgctgatca
    19921 aaaaagaggc tgggacagaa gcgtttaact ccaagaaata agaagaaatt cacgaaaatt
    19981 gcttttcaaa tttttgtgaa tttcagctta tttccgaagg aatttcttct gcttccgccg
    20041 tttatacgtg tttagagcgt gagacaaaag tgttctttac ttttgtccca cgctcttttt
    20101 ccgaataaac ggtgttcaaa agcttgcatc tgcggtaata agtccaacca agttaaaaac
    20161 ataagaagct gtttttactt ggctgttctt attacttgat gcagggcagc tttttcacaa
    20221 cctcttcact aaacagtgtt caatcagctg accctcggta ttagctcaaa acgctgattt
    20281 cacaacctct ttttatttac gttctatttc attcattttc cgaagcaaat cgagctgctt
    20341 gtatgcccgc ttgtcgccca aaaataatga tctccgcaac tgaatttcca ccgatccggt
    20401 tgtttccatg taagccacct gtgacttcac cagcagcata taacccccta attggctggt
    20461 tttctttatc taatacttca gtgttcgtat tgattttcac accgcccatc gtgtaatgga
    20521 ttcctggtgc gattttgatc gcataataat tcggagacga taagtcatgt tccatggctg
    20581 tggcacggtt gaattgagca tcttttttct ccgcaacatc cgtattccat ccatcaactg
    20641 tttttgctag tgtttctttt ggtaaatcga ttttttctgc taattcttcc attgtctttc
    20701 cagttgtgac atatcctttt tggtcataaa attcaatagc tgtggcacga tcacgcacgc
    20761 cttggtcaaa aatcaaataa gctgattttt caggcaatgc tgtaattgct gcagatactt
    20821 tatcccttgt atccatttca ttgacaaatc ttttcccctc ttgatcgacc aagattgctc
    20881 cttctccgcg aacaacctca ccaatcaaga ccccctcatc ctgctgcaca gttggatgaa
    20941 tttgtatttt atccatatca acggtttgtc cacctaattt ttcaatcatg gtgataccat
    21001 ctccagttga tccttcttga tttgtcgtaa tataatcagc taaatcggga cgatattttt
    21061 caataaattc tttgctggca ccaaaaccgc ctgtggtaac tacgattgct tttccggtga
    21121 cctcttttgg ttcttctcct tgaacatgta cagtcacttc attgaccgtt tccccatttt
    21181 tcttaatgtc tgtcacatct gcgttgacaa aaatagggat ttcccgctca tggacgttat
    21241 tcaataaccc ctccactaag tatccaccaa tagccgagcc atcagacgga cgatgtgtcc
    21301 tcttttcact catccctcca gtgatcgtta agttgtccag tttgataccg ttttgatcta
    21361 gccaatcgac cgcatcagca gagtgatcga caaagtatcg aagcatttct ttatcattcg
    21421 ttcctccacc accttttagc gtttcttcat agaaggcatc attcgagtct ttgattcctt
    21481 cttctttttg aaattttgtt tctgaagcat tcataccgct tgatgattta gatgtgtttc
    21541 ctccggcaac aggcatcttt tccaaaatta ctggattcaa cccagcatct tttgcttcga
    21601 tagctgctgc catccctgca ccaccagctc caataatcac gacatcataa gattctttca
    21661 tttcttttgg atctgtatat acttgttcag aagcgcctga tgatacttcg gcagattcct
    21721 tcgtactaga acttgtctgc gctgtatttt tctgatctgc gccgcatgcg ctcatagcaa
    21781 gaagtgcaac ggctgttaat aaaccagcaa ctaatttttt catttgtatc ccccttttct
    21841 ccttatacta tattaagtga tttttttcac aatatcaact ctgtttttct ttaagtcata
    21901 tagctttggt aaacacacgc ttcttagtat aattaaggat atacatgaag gagttatttt
    21961 atgaatcatt tgaaaacctt ttttacgaac agtacaaaaa ctgcaggtag aatcacaaac
    22021 ggaatctata ttttattacg tatcatcgtc gttattatgc tagtggatca ggtctggaac
    22081 caacactggg gaaatacaat gcttttatta ctgacattaa ttttatttga aatcccttat
    22141 tttctggaaa agatattaaa gatacagatt ccaaatatgc tagaaatcat tttgttatct
    22201 tttattttta gttcaacagt tttaggagag ttaagtgatt tttatggcta tttttcaatg
    22261 tgggatactt ttctacatgc attcagcgga tttttagctg ggggtgtcgg cttttccctt
    22321 gtttatttgc tcaataaaaa tacaaaaacc atgaacttga ctcctttatt actagcagtt
    22381 gtttccttct gtttttcgat gacagttggt gttatgtggg agtttgtgga attttcagca
    22441 gataaattac tgcaattcga tatgcaaaaa gatacgatca tccagcaaat caatagtgtg
    22501 gagttaagta aagacggaaa cactgtctat catgttccag atatcactcg gacaatcatt
    22561 gaaagtcaaa atgcagatgg taaaacagat aaaacaatca tccaaaatgg ttacttagac
    22621 gtgggaatca tggatactat gaaggattta tttgttaatt ttattggagc agttgttttc
    22681 agtgtatttg gttacctcta tagtcgaaac gattaccaaa aatttacgtt catcaagaat
    22741 tttattccta aaaaaatcaa acgataaaac atgctaaaaa acaagagaag gggcagtgac
    22801 aatacttttg tcactgcccc ttcttttttg aatgtatggc atgccattag ttatccgata
    22861 gtattaactc aaaaaagtaa gatatgagga atgactattt cgttttttat cccaatactg
    22921 aggacttatt tcaccatttc gttatttatc taatttactt aaaacctgca taactttttc
    22981 ataatctgga ttaggtgtgc cgtctagatt ttcagcaata aaagtaaaac ccattttttt
    23041 ataaagagca atcgcctgat ggctccatgt ctgtgtgtga agatagattg gtccgtccgt
    23101 atggagggta ggaaattctt gcaagactct ggcagtcaat gcttttgcga gcccttttcc
    23161 ttggtaatct ggtttcactg ctaaccaatg aaaaaccgga tacacttgct ctcttgattt
    23221 ttttcgccaa gcggtacagg ttgctacttt ttctcctttt tttgtctcta caaaaaacat
    23281 ccttctttca agttcttcag gataaggagc aaagttttgt tgaaaatact caagtgcttc
    23341 atctgtcgtt tgaaattccc caacggaagt ctcaatctcc gcccaagcag attcatcttc
    23401 tttttgataa aatcgaaatt caaaaccttc cgctaaaggc gtgattggaa cattttgttg
    23461 aagtggtctt gtcatccaga tttctgcgta aggtaacgtt ttatctaaca tttttctatc
    23521 cctcctcgtc tccattatgc caaataacat atgactcagc tacttatttg actataacag
    23581 atagagatat aaatcagaac cagtcatctg cgtcaaattc atttcgatta gcgtataccc
    23641 atgttcctgc catacctcgc atgaaatctc ctaaagcaga agaaggaata cctccaccag
    23701 gtgcgggtgt tcccggacta ggaagtggta cttgcggctg cagatgctca tcggtggaat
    23761 caatagttga caagcgtttt ttcttcgttt ccttctggtc atctgattcc ttctgatctt
    23821 ccgactgttt agcaacaaat tctttttctg attgttgttt tattttaggc tctaaaattt
    23881 cattttccaa tccagaaact tgtggggcca aatgagcttc ttgccttatc gttttattag
    23941 attctgagat ttttctagat attcttgcta actctaggct tcttgtttgt tttactttcc
    24001 ctgttggaga aactgcatga gccatttgtt gttttttttc tgacaagctt tcttcttgtc
    24061 ttttttgttc tttttgatct atctgtttgt ttaatggtaa aacatgtaat agtgactgag
    24121 catggagttc ttggagtgaa tacgggtcat gataactata cataatcgta aaatcacctg
    24181 tttgtttggt caaataacca tcctccaatg gtacttcatt gattgtaacc gatacatcct
    24241 ttaacggtac gggtttacct aaggaatttg ttgctgattg gatcaactct tctttgttta
    24301 ttttttcgtt tggatgaaca ataagatcat gaccttctaa tgaacgattg tctggtatat
    24361 aaacataagt aaaggtaatt tcccctcctg attgcttcct attattcatc agttctgagt
    24421 gaagtacttc aaggatctcc gaccagtgac tttttctgtc taatccgttt gcttgcatcc
    24481 aatcagaaat agaagtgact ttcccatttt gttcataagt cgataaatct atatatttgg
    24541 cactcgatca gaaaattcag caggtaggcg caaatcagga atacgattta cactactcat
    24601 atgtgtttct gcttgaagtt ctttatttgt ttgactatct ataaaatgag tgatgacagt
    24661 cgatgaagca gcagatgctt ctacataaac tacagctgtt gtttctgcca catttgatgt
    24721 tttcgagtct atataagtta atacaacggg atattctccc ggagttgtag tatctactgt
    24781 cccgttcatt ttgatttctt ctttatttcc tgaagttcca tcgctttttg ttacatattc
    24841 aacaagatct ttaggggcgt aactctctcc tgttcttaag tgaagatctt ttcctttgat
    24901 agctgtttga tcagcacgaa catggatcac agcagatgca gtcattgttt ttaaagcaat
    24961 tggatcaaaa taggacaagg aaatagtaga tgttcctgta ttagtcgtat ccacgatatt
    25021 cccattgttt gaaattactt tggacatatc tccttgtgtt ccatctgcgt tcttcagcct
    25081 ttctaccaga tcagatatcg aaacttttgt ccctgccaga acatcgattt tctttctttc
    25141 aaactgtgaa taatcttttt catatacata agaaacttgt gcgcttccac cgtcctttat
    25201 atctgtcaaa gcatgattca aaatatcagt gatctgtttt aactgatcac cttttgtagg
    25261 atcagtcata tcggaaaaga tagaaagcgg cacactgctt ccggtttccg atgtccataa
    25321 tgttttgtta ggaattaacc agtagtggtt tatcgttgga ggataactga ctttattata
    25381 ggaagtcaat gcaggaagta gctgttttcc atttgcatca gtgaaagtat gagtaatagt
    25441 gataggggaa tcagtggtct cagaaacaga ggtacgtacg accttgatgg tttgtgtcgt
    25501 tgcctgaacg ggtacatgca tatagacacc tacagataaa ctgatcagca tcgtgcgcat
    25561 cataaactta acgtagtgtt tttcagaaca cgaccgttcc ttatctaaac gacaagcgtg
    25621 tttatttagt tgttttgaac gtctttttga acacatttat tcttagtcct ccctactctt
    25681 gtctaaacat gaagtagtaa ttttcataag atgatttcat tatataaata aaatcaaaag
    25741 aagatggact attaggagag tatttttttt gattttttat tgtttcaaga aaatcggaat
    25801 aataacttat gtacttttta attttgttaa gtaatatatc tagttatatc tagttatatc
    25861 tagttacctt ttctttgaaa aaaacataaa tcagctaata aatatgtgag acaaagctgc
    25921 catccataaa tactagctga ttttttcagt taaatgtcta tttttttctc tgatgatggt
    25981 atttccaaaa tattcccagt catctggagt cggtggattt ttccaaatta tctgttcttt
    26041 attaaatttt tcaagtaaac aatcagataa ataaatattc gtacgagaag tgattcgact
    26101 ctcaatcaca atattgtaat ttttaaatcc tttcacttga gaaataatgt aatcggtata
    26161 agcagatcct tgcgaaaaat caatacagac atgaatcggt gcttcaaaat atgataccgg
    26221 acaaataccg accaataaaa agagataatc ataaaataag cgaatcatga aacgttcatc
    26281 ttttcccaag aaatagcgtt tattctcttg tatgaccttt tggattgctg tactgaatat
    26341 tggatacgtc tcgaagaaaa actgtagctg ctttttagac gtaaagctag tcatctcaaa
    26401 gtcgaatatc caattttttc gattgacatg catcataccc atacgaagtt cttttcgtat
    26461 atatagtctt tcttcttcag agatttcaat cgaaaatggt aattgatcaa tcaattccac
    26521 tgacattttt tgactaatca tgtggatatc atgaaaatga gcttccgcaa gtccaaatgc
    26581 gccatctaat tcaaattctt cttccgtgat caaaaacaac atgatataag aaatctcatc
    26641 aatgatctgc tctttaggga tatgaagaaa agaaatatgt gataaatcct tgatgatctt
    26701 cattccttct gagctcttaa agtattcatc tgaaaagaaa cgttttccga ttggttgatt
    26761 cccataggcc ctcaacaaac taatagtggt tagcaaattg aatttgattc gttttgttgc
    26821 agacagtttt aaattgaaca gatattcaaa atattgcacg atactctttg cttcattcat
    26881 gacgctttct ctaaatggca tagaaaaacc attaaagacc ccgaaatata ccccaaataa
    26941 tacgttccgt atgtttattt cttccccaac taatatgttt ttctttaact ttatttgatg
    27001 ctgttcaaga aaagagacta attctcttct ttttacatag gctcttgata tgcttaaaaa
    27061 atgattctct gcaaattttt cgatcgttac ttttgaatcc acgatctccg ttaacagtcg
    27121 agcaattttt gatcgttgaa agtagattct tcttaaattt ttgatatccg tcaaattcag
    27181 acgttcgaca tggatctctg cttcttctga aatttggatc tctggctttg ttttgaattc
    27241 agtaaattct ttatttaatt ctatgatata atttcttgtt ttaaatttag acaaacctaa
    27301 tgtttcatat aacttaggca gcactacata attctttttc tcaaattcta aatatctagc
    27361 tagcagcagt ttttctctat cttcctcttc tataaggtaa tccaacttca tatcctacac
    27421 ctcaaaaaat gcctcatacc aattacttga tatgcagatg aaagttcatc ttttcaccta
    27481 tactgatttt atgatggatt atgcttgttt tttcatcagt tattctcatt ttttatcttt
    27541 tttttgagaa tattgcaaaa aatggaaaaa tttatgagga aatattctat attttttgtt
    27601 ttattgtgtt aaaatgtaca agatttgcgc catttgcgta aacaaccaca aaaaagagca
    27661 ggacggccac cgtcctgctc ttttacttat tttaagttcc attacttatt aattggctaa
    27721 acttctgctt gtttctgata ttgcttgttt ttctccaatg atccgcactt ctgtttctaa
    27781 agacacatca aatttttctt tgattacttc ttggatgtgc gcaatcaatt caatataatc
    27841 tgtcgctgtc gcatgatcga tattgacgat gaatccagca tgtttttcag agacttgtgc
    27901 accgccccat ttcaggcctt gcaatcctgc ttgttggatc agctgacctg tatagtgtcc
    27961 tactgggcgc ttaaagacac ttccgcatga agggtattct aatggctgtt ttgattgacg
    28021 caattcggtc aactcatcca ttcttgcttt gattgcttca taatcccctg tttgcaaact
    28081 gaatcgagct tccaatacga tagcacgtaa ttcttggact ttactgtgac gataagaaaa
    28141 taccatttcg tcttttgtca aagttttcaa tgttccatct tcaagcaaaa gatccacttc
    28201 agcaaaaaca tctttgatct ctccgccata cgcacctgca ttcatataaa ccgctccacc
    28261 gacacttccc gggatgccgc aagcaaattc aaatccagtc aatgattctg ccaaagctgc
    28321 ataagtcgta tcaatcagtg aggcacctgc ttccgcaatg accatcgttc ctttgacatg
    28381 aatctgtttc atttcagtca gcatgatgac tacaccgcga atcccgccat cttgaacgat
    28441 cagattgctt gcatttccta ataccatcca aggtatatca tggattcggc aataatcgat
    28501 gatttgcttt acttcttctt gttttttcgg gaatgcaagg acatcagctg gtccacctgt
    28561 tttcgtaaac gtatagttca tcaatggttc atcaaacaat atagtaatcg tggctaagct
    28621 ttcaactatt tcttctttat tcactgagga ttttcctttc ttttctcaaa cgtcctcatt
    28681 attctatcac gcttaataca atcttgccag tcttgttcaa agttgatgac ggtagtgatc
    28741 tttaagcact tcctcacata attcatgact tcttacaact tctttttgtt taagcaattc
    28801 tgtttccgat ttacctaaac ggatctgaga aaagaaggcc tctaccattg gctcaaaccc
    28861 gcgtttgact agcgtgtttg tccagtcgcc aaattctttc actttttttc catcagcatc
    28921 ttgaatgaca agctgggtca gatcgtttac ttcataagta ccatttttac ttgttacttg
    28981 atatttttct atattagcgc cacttgctaa atccatcgtt aaaatagccg tttgattttg
    29041 tgtttctaat tgtaaaatgg catattccaa aaattccttt gtttctctta tctggtattt
    29101 tgttctcaaa atgggttcat ctaataaata cacagctgta tcaataagat gtaaaaacaa
    29161 atcataaagg acgaactctg tcgtttcttt tgccgctatt cgattttttt gcaggtggat
    29221 caaccgctta tctgggatac gtttcaattc ttctaccata ggagcaaagc gccggttgaa
    29281 accgatcatc aaaattattt ggttcttatc agctaattct tgcaattcac gaacttcatt
    29341 tagatggaca ctcagtggtt tgtcaatata aacatggata ccattttcta gacatttttt
    29401 ggctaattca taatgtactt ttgttgctgc gtggatcata catgcttcga ttttttcttc
    29461 taaaagctca tcgatcgttt catatagatg ttggaacccg tactcttttt gaattctttc
    29521 ttttgtttct ttatttcttg ttgcaaaata aaaatcaagt gttccttgtt ttttcgcata
    29581 agttggtaaa tatgcttttt ctgcgatatt ccctacaccg attacaccaa tcttcatcta
    29641 ctttcctcct ggatcattta gttactttca tcttacacca ttttttacta aaatgaggta
    29701 caatagtatc gcaaaggtaa ggaaattaat tcgaaggagt gtgcttttat tgaaatttat
    29761 ctcttggaac gtaaacgggc ttcgtgccat cgtaaataaa aattttttag aagtttttca
    29821 tgagttagac gccgattttt tctgtctgca ggaaacgaaa ctccaagcag gacaaattga
    29881 tttagatctt ccaggttatt atcaatattg gaattacgcg gaacgaaaag gctattccgg
    29941 cacagcgatt tttgctaaaa aaccagcatt gaatgccact tacggaatgg gtatcgatat
    30001 ccatgataca gaaggccgtc tgattacttt ggaatattcc gatttctttc ttgtaacctg
    30061 ttacacgcca aattctcaaa gcgaattaaa acgtttagat taccgattag aatgggaaga
    30121 agccttttat aattatttgg aaaatctaaa aaaacaaaaa ccagtcatcg tgtgtgggga
    30181 tctaaatgtc gctcatcaaa agattgattt gaaaaactgg aaaacgaatc aaaaaaatgc
    30241 tggattcact ccagaagaaa gagcggctct ttctcgactg ttggataacg ggtttatcga
    30301 tacattccgt tatttttatc caacccagga aggtgtctac tcttggtgga actaccgatt
    30361 caattcaagg aaaaacaatg ctggttggcg gatcgattac tttttgacga gcaaagattt
    30421 agagccagga ctagctgatg caaagatcca tacggacatt atgggcagtg atcattgtcc
    30481 agtagaatta gatttgaaat aaagaggttg tgaaaaagtc gtttagtttc gagtattaag
    30541 aaaaattttg tgaaaatggc tttccacatt ttgcataaat ttggcataat accgagaaac
    30601 tggcttttga acactgttta tcgagagatt gtgaaaaagc tgtcctgcat caagtaataa
    30661 gaacagccaa acaaaaatag ttcctcatat ttttcgtttg gttgggctta ttaccgcaga
    30721 tacaagcttt tgaacaccgt ttattaagag gttgtgaaaa agctgcactg catcaagtaa
    30781 taagaacagc caaacaaaaa tagttcctca tatttttcgt ttggttgggc ttattaccgc
    30841 agatgcaagc ttttgaacac cgtttattaa gaggttgtga aaaagctgca ctgcatcaag
    30901 taataagaac agccaaacaa aaatagttcc tcatattttt cgtttggttg gacttattac
    30961 cgcagatgca agcttttgaa caccgtttat tgagaagttg tgaaatcagc gtcctgacct
    31021 gagtattaga gaaacaaatg gcaaaatagt tcctcatatt ttgctatttt ttgagctaat
    31081 acggagggtc agctgattga acactgttta gtggagaggt tgtgaaatca gcgtcctgac
    31141 ctgagtatta gagaaacaaa tggcaaaata gttcctcata ttttgctatt ttttgagcta
    31201 ataccgaggg tcagctgatt gaacaccgtt tagtggagaa gttgtgaaaa agtcgcctac
    31261 tttcgagtcg taagaaattt ttttgaaaat ggttcctcac aactttgcat aaatttgact
    31321 taataccgag aagtcatgat ccccatctaa ctccaaatca caaggaatga gttcaaaaac
    31381 tagcttttct caacaaatat tacataaaaa attctatgtt ttttgttaaa tttatttgct
    31441 tttttcaaaa gtatgttaca gtaatttccc aaggaggttt tacagaaatg aattttgttg
    31501 ccatggattt tgaaactgcc aatcatcagc cttatagtgc ttgttctctt gcgctagtca
    31561 tggtaaaaaa tagccagatc gttgatgaat tctatacatt gatacagcct gagactcctt
    31621 ttttctggcg aaatgtccaa attcacggaa tccatcaaga agacgtacgc aatgcgccga
    31681 aattcccaga agtctggcaa actatccaac catattttca aaaaaatcgt ttagtcgttg
    31741 cacataatgc tgcttttgat acaaaggtct tagcgggatg cttagattat tatcatcttg
    31801 aacagcctaa ttatctttct ttatgtacag tgaaaagtag ccgtcgcctg tttcctgaat
    31861 ttccaaatca tcgattgaac actgtgtgcg aaaatttgaa catccaatta gatcatcacc
    31921 atgatgcatt ggaagatagt cgtgcatgtg cggaaatcct gctttatcaa gaaaaaaaat
    31981 tcgggacaga tccattgaaa aaacttgtga ctataaagta aaagaatact tatgaaacac
    32041 acaaagaggt cgtgagcctg ccgtttcact ccgagtcaca aggagcaatt tcaaaaaata
    32101 gcttctcatg tttattaaat attgtgactg gtgaccgagg agctggcagg agaacaccgt
    32161 ttattggaga ggttgtgaaa aagctgttct gcatcaagta ataagaacag ccaaacaaaa
    32221 atagcttctc atatttttca tttggttgga cttattaccg cagatgcaag cttttggaca
    32281 ccgtttacca agaggttgtg aaatcagcgt tttgacctga gtattagaga aacaaacggc
    32341 aaaatagttc ctcatatttt gccgtttttt gagctaatac cgaaggtcag ctgattgaac
    32401 accgtttatt caaaaaaaat ggactgcgac acgacttttg tcacagtccc ttcgtgtgtt
    32461 tttctgcctt ctcaaaagga tgacagtttc tcactctttt cctatttctt ctattcaatc
    32521 aaataactca ttttatatac atctaaaaat tcacctagat ctgttcttgc ccctctaggc
    32581 atgaccgctt cgatttggaa gcccattttt cggtaaaggt gtacggctct ttcattacga
    32641 acttgaacgt caagctccaa tcgaaaaagt acacccattt ccttcgccca actgatgatt
    32701 tcttctagca taagagtgcc tagtcccatt ccccaatatt cctgcagaat actgataccg
    32761 acttctccca cgtgagacaa acgaaattga ctgtctgcct tgacagatgc tgttccaata
    32821 atcgtccctt catagattgc aagcagcaat aaattattat tgctttcgta tatataatcc
    32881 aactcttctt ctaaggtttc tggtggtaac aggagttctg cttcatccaa aactaaaaat
    32941 tctgtctcct tattaacttg tcccatcatc aaaagaatgt cttttgcatc tcctggcact
    33001 gcttcccgca agatgatccc aacttcttca ctcatgattt tcagcccatt tttctagaat
    33061 tcgctgtttg aaggtttcac tttgctcccc gtatgagatt agtttcacat accgcttttc
    33121 taaatctgta tcactttttt ctaaaatcag ttccaaataa tcctccggca gtgcttcttc
    33181 taatagattt ccccattcaa caacggaaag cccatcacct tcaaaatatt catctaaccc
    33241 taaatctgct ccgctagctg ctacccgata aatatccata tgatacaacg gaatccgacc
    33301 ttgactatat tctctaataa tcgtgtatgt cggacttttg atcatttgcg ttatccctaa
    33361 tccttgggca attcctttcg tcaacgttgt tttacccgca cctagatcac cagtcaatat
    33421 cagattgtca cctggcattg cggaatgacc aattgcctct gcgaattgtt ctgtcattgt
    33481 taatcctgat agttcgatca tttttcatct tctcccgctc ttctttcttt ttgccagtat
    33541 atcgcgtaat gaagtttttt taaagaaaaa atgaactagt caagaacagc agctgctgtt
    33601 tttggctagt tcgcgtgtat ttgttaatca atcaatgttt gtgctgctgt gataatcgat
    33661 aatttatata catcttcttc atttgctcca cgagacaaat cagaaaccgg tttgttcaag
    33721 ccttgtagaa ttggtccgat tgcttcaaag ttaccgaaac gctgagcaat tttatagccg
    33781 atatttcctg actgcaattc tggaaataca aagactgttg cttgaccagc tacttctgaa
    33841 tctggcgctt tcagttgtgc aactgaagga acataagaag catcaaattg caattcgccg
    33901 tcgatcatgt attgtggcgc tagtttttta gcgattttag ttgcttcaac tactttgtct
    33961 acttctggcg atttcgctga gccttttgtc gagaagctca tcattgctac ttttggttcg
    34021 atatcgaaca attctgctgt ttttgcagaa tctacggcga tttcagccaa ttcttgcgca
    34081 gttggattca cgttgatcgc acaatccgaa aagacatatt tttcttgatc tcttccacgt
    34141 accatgatca tcgctccgct tgtccgactg atgccaggct ttgttttgat gatctgaagt
    34201 gctgggcgaa cagtgtcgcc agtcgaatgg atcgctccag agaccattcc gtctgcaatc
    34261 cccatatacg taagcatcgt accaaagtaa ttcacatctt ttaaaatctt ttctgcttgt
    34321 tctttggatg cctttccatt tctacgttca acaaaagtat ccaccatttc atcccactta
    34381 tcgtaattat cagggctgat gatcgtaaag ctagatgttt tgattcctct ggcatgcgct
    34441 gcatttctta tttcttcttc gttccctact aaaatgggtt ccacaagttc ttctgctttc
    34501 aaccgggcag ctgcgcctaa aatacgagca tcagtagctt ccgggaaaac gattttgatc
    34561 ccacggcgaa caattttaaa tcttaaacta tcaaacaatt ccacaagatg acctccagac
    34621 gtttttatat gtattatcat acactattcc agaaaaaaag aacagtttat tttatctgta
    34681 tcagtcaaaa atgctggaaa aattaagttt ttcacataca aagcgaactg cactataaca
    34741 ggaaagcgct gttttattac actgtttcag gcagttgcca atcaatcggt tcttctccta
    34801 acgcaaggag cgcatcattc gttttcgaga agggtttgga accaaaaaag ccacgacttg
    34861 cagataacgg actgggatgt ggagatgtta tgatgatatg gcgactctta tcgatcattt
    34921 tgattttttc ttgtgccggt tttccccaca agataaacac gattggtttt tcccgttcat
    34981 ttaatttttc aatgatcgtg tctgttaatc tttcccaacc tttcccgcga tgagaatacg
    35041 cttgcccttc ccgaacggta agaacggtgt tgagtaaaag gactccctgt ttagcccatg
    35101 acactagatt tccatgttga acaggtgcga ttccaagatc atcataaagc tctttataga
    35161 tatttcttaa cgatggcggg atctttacgc caggttgcac agaaaaagat aagccatgag
    35221 cttgattttc tccatgataa ggatcttgtc ctaaaatcac cactttaact tcttcataag
    35281 gagtcaattc caatgcttca tagatatgat acatatctgg atggatcttt tgggacgcat
    35341 attctttttt taaaaattct cttagatgca gataataatc ttttgaaaat tctgaggaca
    35401 aaacttcttg ccaactgtta tgaatgattt ctttcaaaaa ctccacctcc taataaaaag
    35461 aataactcac attttcttca atcacaaggg acaatcttca ccctcagcac ttgattaata
    35521 tggtaaacta ggaacaagaa gcagaaagga acgataatca ttatgatcaa attaattgca
    35581 tcagatatgg acggcacatt attagatgcc catatgagtg tttctcctga aaatgccgag
    35641 gcgatacgtt ttgcaaatga tgccggtgtt gagttcatgg tcgctactgg tcgaaactat
    35701 caagaagctc gcgcagcttt agatgaggta ggaatcgatt gtgcgatgat cactttgaac
    35761 ggggcacagg tatttgataa agaaggaaat tcattgttta ccgtgtcgat tccaaataat
    35821 caagcaatct ctgttttaga tattctagat gctaacggta tttactatga agtagcaacc
    35881 aacgatggtc tttattctga aaatcaagcg aaacgaattg aaagttttgc ttccatggtg
    35941 gctacccatt tacctcacct tacgtataaa atggcgattg ccatggcctc agctaagctg
    36001 gagttattgc acatcacata cgtggacagt attcgtgcta ttttggaaga aaagaatctg
    36061 gaagttttaa aaattatttg ttttcataca gaagggccag ctgtattagg tccagttgga
    36121 aagcagattt ctcttttagg cgatctagcc gttacttcct ctggtcaaaa caatatcgaa
    36181 gtgaaccata aaaacgctca aaaaggaatt gctgttgccc atgtcgctca cgagcgtggg
    36241 atttctttag aagaagtcat gacgattggc gataacttca atgatgtcag catgctgcaa
    36301 gtagcaggag tcagtttcgc aatgggaaat gcagaaatcg aagtaaaaga ttatgccaaa
    36361 tatacaacgg acacaaacct tgaatctggc gtaggaaaag ccatattgcg cgcgattgca
    36421 gaagacttgt agttttatct agaaaagagg gatatagatg tcagaatttt tcattcagga
    36481 aaagcagctt ggacgtgcaa ctcggacaat tgtcaaaaac gaaaaaggac attccctgtt
    36541 tttgatggtt ggtcgctggg gaacaaaggg cgatgcattg tctctttatg ccatgaatgg
    36601 cgatctcgtt gctcacatca agcagataag cctgacattc ggtacgcgtt ttgagctgta
    36661 taaagagttc gaaaaggtgg gaaccatgca gaaaatattc aattggcccg gtgactttta
    36721 ttatattcgt agacttcact ggacagtcca aggtgatatc tataatcatc aatatcaaat
    36781 ccatcatttc aatcagcaaa tcatgaaaat ggataaagca acactttttt caggagatta
    36841 ctatgtattg gatgtctcaa atgatgaaga tgctccagtt tgtatttgta ttgctgcggt
    36901 tttagattac tggctctacc gtaaagacaa aagtcgcgat aagcctgttt cttaccgact
    36961 taacttaagt taaaaagatg tacctgaaat gcggaaatac gcatttcagg tacatctttt
    37021 tagatattct tttgcatatg atcataaaga tgaccactga tcatccgctg accgacaact
    37081 ttgaagtcat ggcgttcgta taatttttta gcctttggat ttttttcatc cacacttaga
    37141 ccgatgacgg agcgattagc tttcttcgcc aatttaggta atgcttctaa taatcgcgaa
    37201 ccgatgcctt gtcctctaaa atcttctgat acactgatag agtccaaata ccattcgttg
    37261 ggaaacgttt ctttatcaat gaacaaacgt gtagacgcat ctagctgata tttctctaag
    37321 ataggtacca gtggctgatc gatgattgat tcttcttcat ctgtataacc gtaagcaact
    37381 cctgcaactt taccgtctat ttcttctacg atacctcgtg aataactgta acgataattt
    37441 ggatcagtga ttgcttcttc taaaatctct aaagtctttt gttcccctgt ctgcttcaaa
    37501 aatggcagtt ccatatcttt tagaatcact aagatcaatg gggcgatttc tggagcatct
    37561 tcttttctcg caaaacgaat catagtttcc tctccttttc tccattctaa catgcagaaa
    37621 aagaaatcgc aaaatcgtta ttttaaaaaa tcttcaatct tttcagtaat gaaataacca
    37681 tgagtaacga ttcttgccgc ttcagttcgg caataagggc agacgactgg catttcttta
    37741 tcattatgtt cgactacatt attgacttct tcgtatgcaa atttttttcc gcaattaggg
    37801 catttcattt tttccatgtt atctcaactt cctttcatct ttactctctt agcttactct
    37861 tatattgtaa aaaagagaag caatatcctt cttctatgca gatatccata cctgacggtc
    37921 ctgttctcca tctattaatc ggactttata ataaggacgt tcatctttga ctagaagtgt
    37981 ccactctttc acttttgctt ttttcccgta gtagctgact gcttccttca tcgctgcttg
    38041 cggttgtttg aactcttccg ttttttctat atcaaaaaga tgttctgcgg ccttttccgt
    38101 gtcatttcgt acggttgttt tcccagtgga tggattgact gctatgactt gtccttcaca
    38161 aaaaaactgg tattcatatg ttgcattcgt aggattctcc aaatcttttt caactgcaaa
    38221 atgaatagca gatatgttat gttcttttgt ttcgtttttt acgattgctg ctgctttttt
    38281 caatgagatc cgatattcct ggtcactaat atcatccatg tgaaaagcgg cattgagcag
    38341 tcccgtcata ccggtaatcc ctattacgat gagggcagca acaccaaaca tcattttttt
    38401 cattcttcat tctcctgttt ctttttttta aagaatatca agaaatgaac gaatgaaaaa
    38461 tcgaatgaaa cgaaaaaaaa gtgacaattt tgttatcttt attcgtgcag ttctaatggc
    38521 aatccgtctg gatcaaagaa aaacgtcatt ttttttcctg taaaggtatc ttctctaatc
    38581 ggttctgatt cgatccctaa ggactgcaat tctgcaattg tttcttcaat atcgtctact
    38641 ttgaaagcaa gatgacgcaa gccacaagct tctggatagt ttggtcgttg tggcgcatta
    38701 gcaattccaa aaatctccaa ttcagcactt cctagtttca gatctaattt atagtcatct
    38761 cgttctttgc ggtaattttc tctgattact tcaaatccta atttattaac ataaaaatca
    38821 cgtgatttct gataatctga aacaatgatg gctatatgat ggatcgttgt aaggttcata
    38881 tgagcactcc tattcttcgt ttaagctcgg atctatatta atctccagtt ccattgtaaa
    38941 tgtgtcagat tgaaaaaaat agctgttttt cctttttata agaaaaaagg caaaaaaaac
    39001 agaaagtagg tcctccaaga cactcttcct gttcccaata taataaatga aagtaagaaa
    39061 ttatattttc aagaaaacaa acagaaaatt atcataacac aaattattta taattgaaag
    39121 actagttttt tttcaagaaa agcatacaat agattgtgtt agtaaataca gaacacacta
    39181 catttagtgt cttaaggagt cctcatacat gaagtcatat tttcagtttt tagctcatca
    39241 gctaaaaggc tggccgcaac aaaattatta tcttttcttt ttcagtcttg gctgccaggt
    39301 catgactctt gtcaatagtc ccatcacttg gctgtccgtt attacattta tcggtaccac
    39361 gcttggtgta ttgtgtattt tatccatcaa tgcggcaaaa tcagtcaacg gtattttagg
    39421 tattttgtct gcgatttgtt ttattatcgt tgggttttca gcaaagaact atttaagtat
    39481 cggtgaacag attgcttata tgatcacatt ggatatcccc gtattgttaa gtaaagaatg
    39541 gaatcataat atggcttcaa aaatccgaaa attcactgga aaaagctggt ttatcgcaat
    39601 catcagtact ttccttgtct atcttgtttc aggattcctg attggtcgtt atacagatga
    39661 tcctcggccg tgggtagatg ccattgcttt ttctattagc ttgactgctg gtatcatcag
    39721 tttcttgcgt tacaacaacc aatattactg gtggttagct tcagggcttg ctcaaatggt
    39781 cctttggtat atttcattta cgcatggatc tgcaagtttg gcgatgttcg tgaacagctc
    39841 tgtttacttg ctgaatgatg tccttgcatt taccgtttca ccttggtata accaaaaaga
    39901 acgtgaacgt atgcaaaaaa tggaagaaga atactacaac gcacaacaac acgcataaaa
    39961 aaactgagcg tgggacaaaa gtaaagaaca cttttgtctc acgctctaaa cacgtataaa
    40021 cggcggaatc agaagcaact ccttcggaaa taagctgaaa ttcacaaaaa tttgaaaagc
    40081 aattttcgtg aatttcttct tatttcttgg agttaaacgc ttctgtccca gcctctattt
    40141 tttatagtaa ttccttcaga tactttcttg cctcatcatt gaaacgcagt gattcttcta
    40201 acttctgata atattccaac gcttgtttct gagcttcagt aaaacgataa tgttttcctt
    40261 tccatttgtc gattgtctct tgcacatttc cagattggat atctttcact actagttgcc
    40321 atttttcttt tgagactgta cggtctttct tatcagcaga ttgtatagct tctcgttctt
    40381 tacgcaatac ttttaaaaaa ccatttctga ctatccgagg aatgctgtcg aagaaccctt
    40441 ctgtaaaacc atagcgacaa tattgcttcc aaataaatag atagattttt ggttggatga
    40501 atcgttggtt tttcgcaaaa tattccatct gagcagtgac ttctggtgtt cgttgacgtt
    40561 ttgtctttct caacacggaa ataaatgttt caaaataagc attaggatgt actggcactt
    40621 cttcatatac gatggattgc caatctttac gtaaaaatgc gcgatagttg atcaagaatt
    40681 cttctacatc ctttactaat tcttctgcaa agtcgtcaaa tagttctttt tttatctgtc
    40741 gcttttttga ctgcccattg atgtgttcac ttattttctt gatttcattt tccaatgctt
    40801 gataatccgc tatgtaaatc ggcatttcta cttggcgaaa ttctgcgagc cgctgagcta
    40861 attttatatc cggtaaatat ggctgtttca tccgacgatt ttggtacaag acaaaacagt
    40921 atttttgcca tagtccttca ggaaaatcga tattcttctg cttaagccat aataattcgt
    40981 ctaaggccag atcaactttt gtcattccct gatggatcga agctgccact gtcggagaga
    41041 catgcaggtg atcggcaaag tggttgatgc ctagttttag gatctttccg gtttttggcg
    41101 atttaacgat gtattgcact tttaattctc taccacactc acaatacaat ttttgctggc
    41161 ttcgttttgt tcgaaaaaac ggattgatct tgaagtcaga aaacacccaa tctgttgcag
    41221 ctaaataatg ttcttccata aaacgagagc tgattagata tcggcggtgc ttatcgacta
    41281 gttcccgctg ttttttcgtt aattttgcat agatctccca acgttgactg cttgtgtatt
    41341 gtttagaaat tttgatggga tagcttttgc tgatttcttt tggaaaccat tcttcaaaga
    41401 cggattgcca ttcttccacg gctgtttctt tcctttctaa ttacaaaaag ctggctacta
    41461 acataacgtt agcaaccagc cagtgtttct tgctaaatta gtgagttgtt ccggcatttc
    41521 cggaaatatc ttctttattt tctactgctg cttcaactgc ataagtcaaa gaagaagcaa
    41581 tgtcttctaa agacatagaa ggcgtaccca ctggacgatc gatcacttga tcgggtgaga
    41641 atggcacgtg gatgaaccca cctcgaattg ccgggaattg tgtttcgatc aaatgaagca
    41701 aacgatacat gatatcattg cagacaaatg ttcctgctgt ataagagatg tacgctggta
    41761 gaccatgatc ttgtacattt tttgtcattg ctttgattgg caatgaggta aagtaagcgg
    41821 ctggaccgtt ttcttctaaa gccgtatcga atggctgatt tccttcatta tcagggattc
    41881 ttgcttctgc tagattgatt gcgacacgtt cgaacgagac tgctgaccgc ccacctgctt
    41941 gtccgacaca gatcacgaca tctggttggt gctgttggat ggcttctttg actacttgac
    42001 tgcttttttc gaatacggtc ggtacttcca ctttgatgat ttcagcaccg ctgatttcat
    42061 ctggcatttt ttttactgct tcataggctg gattcacttt gtccccacca aatggatcaa
    42121 aacctgttac tagtactttc atctgttgtt cctccgtccg attgatttaa catatggtta
    42181 tcttttatca taccattttc cttgaacagc gtaaataaag gaaacaatag tttaaataac
    42241 ataacagatc aaacttaata tattcttata aaaaaatagt gttccactac aatgttagaa
    42301 gaggttgcga caattattct gtcacaaccc ctctcttcta ttatttaaat agaatcatat
    42361 aagcaatttg gaaaactagc ataaataacg caataaacaa ctggtttttg atcactccgt
    42421 atttgtcttt catctccagc atcgctacag gcacgatatt gaagttagca gccatcggtg
    42481 tcagcagggt cccacaaaaa ccgcaagtca atgcaaccat tcctattaac gctggattcg
    42541 ctccatgact aaatacgaat ggtgcaccga tcccaaccgt catcacggtg atggccgcaa
    42601 atgcattccc catgattacc gtaaatatca ccatgccaag agcgtaaatg atgatgccga
    42661 tgttcacatt tccttctgga acgatcgtac ctactgcatt ggaaatcact gtcccaactc
    42721 cagcgcttgt aaataccgca cctagagaag ctaaaagcat tggcaacatg cttaacggcc
    42781 ctactgtgcc cagcatatct gctgcatcat ctaaaaatgt acttggtcga ttatctcgag
    42841 aaaagaacat caagattagc atggctgcaa aaacaccgac gcccacgccg actaaagcac
    42901 ctaaattggt aaatagagca aacaagatcg caaagacacc gatactcaaa gctggaataa
    42961 aaattttcat tcctagtttg tctgacattt tttccatata ttcttttgat ggaagccggc
    43021 tttctccttt gctgactttc ttagcaattg ctggtatggt catcgcaaag atcaagccac
    43081 cgttcacgat tgccggaagc catcttcctc ctgcaataac tacccctaag accgtccaga
    43141 aaaaggctga cccataacga tgaggattgg ttttatctgt taaatttctt actccagtgt
    43201 aaatcaatac gagtcccatc acgatataaa ggatctccag taatttatcg cctaataaaa
    43261 tatcaggatt tgtaaaaaag tccatcttat tgcccctttc ctggataata tttcttcgct
    43321 aatttctttt ctttaagata gaagtagaca cttgccacaa ctaaagccgt gatagccact
    43381 ggaacttcca ctaaagcaag ctgtcccaat gttacgtcat atcctagatc tttcagtgtt
    43441 gattggacta gcaacgcccc tgctcctccg atgaatagta cttggccaaa gaaccagcag
    43501 acattttcca tagctgaagc catacctttt agttcttctt catgcttagg atggacttct
    43561 aacccttttg attcgatggt ccccaatgcc atcggtaaaa tgattggacg aacaaatcca
    43621 gcaactccac caaaactcac gttaaaagcc gcaaagatca ttcgaaagat cccataaata
    43681 tctacaatca taccagcaga tactttcttg aatcgcttga tcaaggaagc cgctgattct
    43741 ttcagaccat ttctttcaag cgttcctgtt gccaacataa tgatgataaa aatcgccatc
    43801 ccgcgattgt ttacaaaact tgtacctaaa agttctaaca ttccttgaat gccaagaccg
    43861 ccagtcaaag ctgtaacaac taaagcaacc attacgatca atatcgagtc taatttaaat
    43921 gcaaacccga gaataacaat caagacgcct aaaaggctaa gataattttc catatatttt
    43981 cctccataaa atgacaatat ttttttaatt ataaagcaaa acacataaaa aatatagttg
    44041 ttttctcacg aaatagacac tatttttaaa tatttttcgt tattttttta tcacaaaaat
    44101 tatcttactt attgtaaggt aaagcttttt ttaatttatt gcccgataat atatagaaat
    44161 aaggtctagt tactgttttt tttaaatgat taataaataa caacttcttt ctatgaaatt
    44221 gcaaagcatt catcttcttt tccgctaacg atatatccgt cagtgcttgg tacactttac
    44281 taaaaagtat gagattgccg atatctggat aggtgtgcta tactacagaa aaagatatac
    44341 aatctgccac cgggtaggat aaagaggatg atcattccat taggtctttg aagggatgat
    44401 tttcctcttt ttgtgtattt ttttatagtt aaggaggaat gtaagtatgg catggatgga
    44461 attaatcata gcaggaattt tggaagtatt ctggtcaacg atgatgaaat ggagtgatgg
    44521 tttttctaaa atcaattatt ctttttacac agtgattggc atgattgcta gtttttactt
    44581 tttgtcaaag gcaatcaaaa gtttgccgat gagtctctct tatcctatct ggacagggat
    44641 tggcgcagtt ggttcggtca taattggtgt ggtcttgttt catgataagc tgaatctttc
    44701 cacttggttc tttgtgggga tgctactcat cagtatcatt ggcatcaaga ttactagcgg
    44761 ccactagaca cttggaataa gtactgatca gaaaaaataa gcctttttat ttaatattca
    44821 atttttttat gaaaaaataa gaaataagtc caatgaccta gcgacttctc cactcatcag
    44881 gtgtatgctt gtactatcta tagaaaagga gtgaatattt ttgaaaagtc tttcggtcca
    44941 agaattatcc aagaactttg gtcacaaaca agccctcagc gatgtcagtt ttagcttatc
    45001 ccctggcaaa atcgttggat tagtaggtcc taatggcgct ggaaaaacaa cgatcatgaa
    45061 agctatttta ggactgatcc attactcaga tggaacaatc tgtattggtg aaaatgagat
    45121 ttctccctct agtcataaag ggttggaaca agtaggagca ttgatcgaat acccgggtat
    45181 ctatccattc ttaacaggct atgatcatct gaagttattc tctgaaacca acgatgtatc
    45241 tgctatcgac actatcgtga atcagctcaa gatggaaaag tacattcaca aaaaagcgaa
    45301 atcctactcg ttgggaatga aacaaaaatt gggaattgct cttgccttac tgaaccatcc
    45361 gtctatcgtt attttagatg agccgatgaa cggtttggat ccacaagcaa caagagatgt
    45421 gcgaaaaatc attaccgact tggctactca gggcacctct ttcttgatct ccagtcactt
    45481 actcagcgag cttgaaaaaa tggtcgatga gctgatcctg atcaatcaag gaaagatcat
    45541 caaacaatgt acaatggctg aattgaacca aacagcgcaa gatttcatcg ttatctctac
    45601 aacaaatgat ctagctgctc gaacgatctt gacagaagct ggatatactt tggaagatcc
    45661 tgataaaatc aagcttttaa aagaaaacga agaattatta ggaaccgtga tccagctatt
    45721 gtctgcacaa aatatccatg tgacagacgt ccagcatctg acgaatgatt tggaatcttc
    45781 tctattggaa attctggatt cagtaaaggg ggaagaagaa aaatgacatt gcttgtaaaa
    45841 caagaattat ttaaattgat caagaaaaag tcaactgctg ttttatctgt tctattagtt
    45901 gttttgctca taggaacagc acttctagcc aaaaaataca cgacgatcat tgatccagtt
    45961 gaaatgactg ctcagctttt tagtgccaca tcttggattg tctttatcat gattgcagct
    46021 gcaagcacga tcatttcgat ggaagcacaa tatggtacat tgaaaaatct cctttatcga
    46081 aagtattctc gaggagaaat attagtaagc aaatggatca cattagttat ttattctgtt
    46141 tatttatacc ttttagctat tattgtcact gtgttgatga aactgattct tttcccttcg
    46201 atttccttca cggagaaggt ttctactggt caaacactga tccaaagctt gttcacttat
    46261 actttgggta gttatatcgg tttatggctg attttaagtt tagtgttgat gattgcttgc
    46321 tttatcaata gttccggtgc atccatctca gcaggaatcg tcttttattt tgcttcgtca
    46381 atcatatctg gtatccttat tgcactcatc caaaaatggg agtggatcaa atggaatccg
    46441 atcagtatgt tgaatctgca aaaccaaatt ggaaacgaag agatcatgaa gcaattgact
    46501 catctttcta ctaatcaaat gctattcggt aatttagctt acatcgtttt gttcttagca
    46561 ttaggatatc tcgtatttaa gcgaaaaaat gtatgatgac tcatcaaaaa agaggctgtg
    46621 aaagagacgt tcagccttat tgccgattgg ctgtctctta aacaccgttt attctgaaaa
    46681 aggagctgtg acaacatttg tgtcacagct cctttcctag tatgtttttg aataaacgac
    46741 aggctcacaa cctctcttta tacttctttt atacttctat acgtgaagca tcccagtggc
    46801 aaataaaacc attgcaatca ctccgaccat cgtcacacct ataagtaaaa tcttatctaa
    46861 gtggatatgt tgtacaggct cgttttgctc cttacgtgct ttgaggtaaa aataaatgcc
    46921 tggcaagaaa agaacaagaa caagcattac ttcattaaag gctacgacta gcatagccca
    46981 tacttgaaag gcacttgcta aaagccctac taaaaattgg acccattctt tccgctgata
    47041 agaaagtttc atttggtaca atcctaagaa aagccacgtg aagaaaatag ctgctgtacc
    47101 aagtgtgtaa gcaaagttat aagcactgtc agtgaataat aatgaaagta aaaagacatt
    47161 cgtacataac gtcgtcaata cgatagcata agttggtgcc ccatttttgt tgagttttcc
    47221 ccatgcttta ggcaaaagtc cgtcttcagc catgtttccc attgtttcaa tcggtaagat
    47281 cgtccatgag agccaaacac caactaaaga aatgatcaaa ccgccgttga tcacgactgc
    47341 tccccattta ccaaccatca tttcaaacac atagcccata gcaggctgcg ccttgatcgt
    47401 ttgcagctga ttcatcgtca ttgtcccata tggaagcatg gaaaccaaga cgtaaataat
    47461 aatcaagccg aatatcccta gaatcgttgc tttcccaaca tctgattgtt tttttgctcg
    47521 tgaacctacg acagaggctc cttcaatacc aacaaatacc caaagcatca ccatgatgca
    47581 actcaatact tgactggaaa acgggatcgg ctgtccattc gcattcaata taatgtcgct
    47641 agaaaagtta tcaatgaatt gttggatcga aaacgtgctg atagctacta caataaataa
    47701 aaataatggc actaatttac agaatgtgac gatagcattg acgaaactag cattttcgac
    47761 tccccgattc actagccatg catatcccca taaaaagact gtactcatca cgatcgatgc
    47821 cagattttgc ccaccttcaa atactgggaa gaaatatcct aatgcgctca tcaacaatgt
    47881 tgcaaaagct acgttgccta accagcatgt gagccagtaa ccccaaccgc tgataaaacc
    47941 agcgaaacgg ccaaaacctt cttctgcgta actaaagatc ccgcctttta aatctggacg
    48001 ttttttattg atattattga tcgacaagga gagcatcaac attgctgttc ctacgagtac
    48061 ccaactgaaa atagctgggc cgccagccga tccggagatg tccgtcataa taccaaatac
    48121 gccacctcca atcgctgaac caattactaa ggcagcaagt ggaattaaac caattccttt
    48181 tttctgttgc tctgtatcca tgtaagcatc ctccaaaata aaaccgcttt tatcaaaaag
    48241 tataacaaac cttttttatt tttacttaat taataaaaac tttaatagaa atataattct
    48301 accggctttt ttctcattat acaagcaaag cgcctagtcc ctttccaaat tacaccacca
    48361 aaaaacttaa aaaagatgct atactaaaag gaaagaattg gaggatgatc catgaacatt
    48421 ttatatatat cgatttcagg aaatacgcgt gcctttgcca aacatctagc agaatatgct
    48481 gaaaaaatgc atgcagaaga tcctgtcaat cctgaagtta ctttaaaaga aatccatgaa
    48541 aatagtgatt ttacgaaaga aacagaacca ttttttactt tcgttcctac ttatttagac
    48601 ggcggaaatg gtttagataa cggtgataca gaaatcttga ccgaaacgat gcgtgaatat
    48661 ctggaacatg aagacaatca taaactttgt cttggtgtag tcggtagcgg aaataaaaac
    48721 ttcaataatc agtattgtct aacagccaaa caatatgcac aaacatttgg ctttcctttc
    48781 ttggcagatt atgaattacg gggaacacca tctgatgtga cacgaattta tcagatttta
    48841 gcagaaaaca ataaataata aaaaagaaga agctgaaaaa tagatttcag tttcttcttt
    48901 cgtttctatt gtttctatca tattaagctt tgacatccat cacaggtgct tttgcttttg
    48961 ctttacctgt tttttccaag acaaagtttt ttacacgatc catattggtt accaagacga
    49021 tcatggatgt ttctttgcct gctgctttga tcgcttctaa gtcagcttct gctacaagcg
    49081 tatcaggtgt cacttgctgc ccttctgtta ctttcacatc aaatggcgta ccgcctaagt
    49141 caactgtgtt gattcccata tgaagcaaga tttctaaacc atttggcgtt gtgatcccaa
    49201 tagcgtgttt cgttgggaag acagagctga ctaccccagt aactggagaa tagatatgtc
    49261 cgttttctgg ttctacaaag tagccttcac ccatcatctt ttgtgcaaaa actggatcac
    49321 ttgctttatc taaagaaaca actgttccgt cagcaactga tgagaggata gtcacacttt
    49381 cagctgaagt ttgaggtact actttttcag gcacttcatt tactgtggct gtttcagtcg
    49441 ctaattcttc tttttctaaa cggtctttag gaataccgaa gaagaatgta gcaacgaagc
    49501 caccagcata agctgccaat aatccaagga tgtagcctaa ccatttaccg tcagagatca
    49561 atgggatcaa agcggctcct gaaggtccaa tagcgatagc cccgacattt ccgatcattc
    49621 cgatcactgc cccgccgata cctccaccga tacaagcagt aataaatggg cgtcctagag
    49681 gtaatgttac tccgtaaatc aatggttcgc cgattcctag gatcccgact ggtaaagctc
    49741 ctttgatcat ttctgttaat tctttatctt ttttgcagcg aatccataat gccaatgctg
    49801 cacccacttg tcctgcacca gccatcgcaa gaattggaag caatagcgta cgaccagttt
    49861 catcaatcat ttgcacatgg attggagtca aaatttgatg cagtccgaac ataaccatcg
    49921 gcaagaataa tgtgcctaga acgaagccgg caaatgctcc accaacgcca agtacccagt
    49981 tgatcccacc gaccatgcca tcagaaatga aacctgctaa aggcatgatg aagaaaattt
    50041 caatcagacc gatggcaatc aatgaaagag ttggtgtaac gatgatatct accgcatcag
    50101 gtactacttt atgcagtttt ttctcaacga ttgacaatag ccaaacagcg aagatgacac
    50161 ctaggatccc accttgtcca gctgcaagag cttcaccagt aaataagttt ttcagtggtg
    50221 cttccggatt catccctgtc agcatcacaa cggccccgat aactccacca agagttggtg
    50281 ttgcaccaaa aacttgtgca gcattgatac ctgtatagat aactaggtag ctaaacatcc
    50341 cgtttttcaa gatgttcatc acatcgatat attgttgcca tgttgctgca tcaagtgttc
    50401 cggctgtgac taagtttgct aaaactgcgg caatccctgc cacgatccca gtaccgacaa
    50461 atgcaggaat cattggcaca aagatattag aaatgtcttt taataccgat ttgattttag
    50521 atggtttttg tttcgatttt tgtgccgctt tcatttcttg tgcccgttcg tttacacggt
    50581 cttttccaga tgctgatgaa tttgctgtag ctgtacttac agaagaaagt ttttctccta
    50641 atttcacgcc tgccaaatca accatttgct gtgctacttt gttcactttc ccaggtccga
    50701 tgatgacttg aagctgttca tcttctacta caccaagcac tcctggaatc gcttttaatt
    50761 cagagacatt tacaagatca tcattgatga tcttcatacg cacacgagtc atgcagtgga
    50821 caatgctttc tacattgccc atgccgcctg cccctttata aatttgtttt gccagttctt
    50881 ccaaagtcag ttcgtttttt gccatggtct tttccccctc ataaggtccc ttttacaaat
    50941 ccgtttgctt cagctaattt tgcttgagct tcctctttat cactatttgt caaaatcatg
    51001 acgatagcca gcttaacatt ttgatctgct tcttcaaagt acttttcagc tgtttcgtaa
    51061 tcagcttctg tcgcttgcat gatgattcgt tttgagcgtt cgattagttt ttcatttgtt
    51121 ggtttgacat cgaccatcaa gttattgaat actttaccta taccaatcat actgatagta
    51181 gaaatcatat tcaagataag tttttgtgct gttcctgact tcaatcgagt agagcctgtc
    51241 aaaaattctg gacctgcatc gacttcgatt gggaaatccg cgtgtttact gatttcggct
    51301 tgtttattgc aagaaatcgt tcctgtgaca gcaccgatcg attttgcgta atctaatcca
    51361 ccgatcacat atggtgtacg accgctagct gcgataccaa taactatatc attttttgtc
    51421 aaattcagct tgattagatc ttcttgccct agctcataag aatcttcggc cccttcgaca
    51481 gctacagtca ttgcttcttc tccaccagca attagaccta tgaccatttc cggttctaca
    51541 ccgaatgtcg gtacgcattc agcagcatct aacacaccta gtcttccact tgttccggct
    51601 cccatataaa tcagacgtcc acctttttta aaggactcaa tcgtgttagc aatcactggt
    51661 tcgatacttg tcagttcttt ttcaaccgca gcggccactt tctgatcttc tttgttcatt
    51721 agttgaacgg cttgagaaat actcatctca tctaatccaa aagtttcttg gtttctgcgt
    51781 tccgttgtta ggttctctaa attgattttg ctcattttta tcttccttct tttcttataa
    51841 attgatagtt cataccagct ttgatttggt tgatcaatgg tagctcttct ttgataactt
    51901 tagctactac attcactttt tcatccgctg gcaaatcata tttggttaat tggatctcac
    51961 ccatatagcg caaatacttt tcgttatcta aagtaataga ccctttcata cgcgtagctg
    52021 tatttcttgc tgggataggc ggaatctctc gaaaacgtgc atctacgctt cgtatgacat
    52081 ctcttgcatc gtcttgccga ttcgtatgct tccctaatat atattcgtaa aattcttcat
    52141 ctacaggttc cgtatggagc aagactgtct gttctttttg gaaagaagca aattgctcct
    52201 gaacgttttc tgacagacct gcatctccga tgtaaacaat atccgtgtta cttgctaata
    52261 gatctagagc gcctgcaaga ggatggatcc ctcgatgttc ttccaaagtt ggcaatcctt
    52321 gatatagtgg gcctctcaac tctgtatctc ctggtacaaa accttggaca aggagacctt
    52381 gaattttgag ccattgattt tttttctgat accattcttt gtccagccct gtttcgggac
    52441 gtggataata attatgccaa gcttcaatct gtgagaaatc agcttctgct tctttcaatt
    52501 catcgatatc tttaggcgtg atcgtgctag cattcaaact gattttcaat tgatgtgacc
    52561 agtcggcaat ctgctgattg gaaatatgat aatccattct taaacctgtt acaccaattg
    52621 ctttcaaagg cgttagatct tctaatgaaa aacccgctcg ttccaatgcc tctcctgaaa
    52681 tatcgaccat caattctagt ttattctttt tcgcttcgct tcctagttcg atcaatcgct
    52741 tttgatatgc cgaaacatca tcttctggta tatgcatgga agtgaaaata ccgacaaagc
    52801 cattggatgc catttggcgg atatactgtt tcttctcttc tgacaaagaa tcgttcataa
    52861 atattgaaaa gccaaacata ttatccctct ttttctgtat ccgtcttcat ttctatgact
    52921 agagtatata tctaaagaaa caaaatttca atacttttat taaaataatt aaatttcatt
    52981 tctaaaggtt gagtttatat tatcaaaaga attgtcataa cctaaaaaag gcactgctaa
    53041 gcaaaagcag tgccttgaaa tattttattt aaataacaca aaaacataat tactcataag
    53101 aaaccaattc tgtattatct accatgaatg taaagaaccc ctcattaggc atcggatgaa
    53161 aataagcatt gatcactctt atcaaggcat tatggcaaac taacagatag acattttctt
    53221 cgtcttcgat gcattctttc aataaaggaa cgatccgtgc atacacatct aagactgact
    53281 ccccatttgg gaatcgtaca gcgaacgcta aacgtgcttt ttgaaagttc tcatctttgc
    53341 ttggcagtcc atcataatcc ccaaaatcca tttctaccaa tcgttcatca acggtcagcg
    53401 gcaagctgag acgatcagca actgcttgtg ctgtatctct tgctcgttga agaggggaat
    53461 ggatgatttt cgtgattgga acaggcaaat ctactacctt ttctgctagt ttctgtgcct
    53521 gcatctgtcc tttttcagtc agcggcacat ctgcccgtcc gcaaactaat ccttgtgcgt
    53581 tccaagttgt ttctccgtgt ctcgttacat aaagcatgtg attctctcct tcgttggcaa
    53641 agttcccctt aaccatacct tgttgttctt gagattacaa gggttagatt ctctcaagag
    53701 aaataatctc agtagatact ttatccagga aggtttgatc atgttccact agtaacatgg
    53761 caggtttcac gttcaagatc agttgttcta attgttcttg attgaagaca tccaaataat
    53821 tcaatggttc atcccatgta tatagttcag ctggctgtga taaagattta gccaattcca
    53881 cttttttccg ttggcccata ctcatctgct cgatcttgtt atgaaaaaca tctctttcca
    53941 tcccaagctt tcggaggttg ttcaaaaatg cttggtagtc tacttggttt ttctctgcaa
    54001 attccgccaa cgttcctcga ttgtcttcat aattttggct tgcataacta atgctcagat
    54061 gttttggctg gtatttttct cctataacct tgccgttgaa tgcccccaga agataatgga
    54121 taatggatga ctttcctgca ccgttaggac ctgaaatcgc cacccgctga tgaggctcga
    54181 ttgtaaaatg aattggctcg aataacagat tttcataccc taattgaaga tcttctacgc
    54241 ttaaaagtcg cttatggtga gacgcttggc tattcatcgt caaagaatcg atatattcga
    54301 tatcttttaa tagtttttct ttctcgctga tctgggtctc catccgattc acgattgctt
    54361 tggatcgttt catcgtccgt gcagcatcag cacccactgc tcctttattc actcgtctag
    54421 attcagtatc gatgaatccg acttgtttct ttgttttatc tccttctcgg gaacgagacc
    54481 attcggcttt ttcagctgct gttttcttta gcctactgac ttcttttttc aatttttcat
    54541 tttgagccat ttcaaattca tcacgaagtt ttttctgttc ttcatagata gagaaattcc
    54601 cttgataaag ttccagttga cttttttcga ttgctaaaac atggtccact acttcatcga
    54661 taaatccccg gtcatggctg accacgatga agccttgttt tttctttttc aaataagccg
    54721 ctacttgttt tctaccagag atatccaaat gattcgttgg ttcatcgatt aacgggaaat
    54781 gagtgtcatc cacaaataaa agtgccagta ggacttttgt cttctctccc cccgatagtg
    54841 tgctgaattc tctccataag atttcaggat ctgtttgcat caattggagc tctctttcga
    54901 tttcccatat ctcaaaatcc gtaatatcat ttaacacgta ataggttaaa cgttctttat
    54961 cttttgtctg ttgcgggaaa taggcaaatt cttgctgatg gattacttgc ccttgataag
    55021 gtagtttgtt ttgtagaata ttcagtaaag ttgtctttcc tcgaccgttt cgtccgataa
    55081 gtcctagttt ccattgtgtg tcaaaattta gatttgcttg ttcaaataat aatgtgcctt
    55141 ggctgtcgta gccgaatgtc agatttttta tttcgatttt agacattttc catcacctcg
    55201 taaaaaaaga ccagtcctat tttcagaact ggctaaagag gatgcaaggg ttggatacac
    55261 acaaaaagac ccatacatcg aaaaaaccaa gccaatcccg aaaatctgca cactgcttcc
    55321 ttgtctccac aaggtacagt ctgaatgcag ctttcatcaa tcgacttaat ttttcaatgc
    55381 acggatccct cactttgtcc tatatttgaa attacgatag cataaagaaa atgattttgt
    55441 caactacttc gggaggatgg tgaaaaatct gctaagtgtc tgtcctaaga tttttgtttt
    55501 ttctaatgtt tgcctgtgtt ccattgcttc ttctaaacct attggaccca aatgaatact
    55561 taagacaatt gggagaaaat cagaaagtcc ttctagctct tggtctctac ttccgcaaat
    55621 agcgattatt ggttttcgat atttttttgc aagcactgct acaccgtatg gaacttttcc
    55681 gtggatcgtt tgctgatcga tccgcccttc tcctgtaatg atgacatctg cttgttcgat
    55741 ctttttttcc aatccagtga tttggctgac taaatcgaaa ccagaaacca tcttcgctcc
    55801 caacaaaaaa agggctccac caataccgcc tgctgctcca cttcctggaa tatcatctaa
    55861 atccacctcc cagaaatctt ttatttgctg agcaatcttt cctgcttgtt tatctaagaa
    55921 agctagcgtc gtatctattc ctcctttttg tcttccaaat tgccaagcag ctccttgttg
    55981 acctgtatat ggattggtaa catctgcagc gataatcaat tttactttag aaacaagaac
    56041 gtttcttcga tcaaaatgaa gttttttagt agataataaa ggatttcctt ctgtgtaccc
    56101 ttctaaagaa gcacccaagg attggagtaa tcctagacca ccatcgctac acccgcttcc
    56161 tcctaaagtg acaataattt gttctacttc ttgaagcagt gcatctttaa taagttctcc
    56221 taaggaataa ctggaagcaa gtcggatagt ttgatccgtt ggtttatcaa gtagatctaa
    56281 ccccaatgct tgtgcagatt cgatgactgc ggtgtttttt ccttgccaag ttgtcaataa
    56341 atagctgatt tttcgctgac ggaataagag atccatccca tcaatggtac gccatgttcc
    56401 cctgagcgcg taatagattg cttctgcagt attttctccg ccatctgcaa tcggcacatt
    56461 gatttttctt cctttacgat cttcccagcc atttagaact gcctgattta gttcaaatga
    56521 agaagcactt cctttaaatg aatcaattgc cgccaaaata tccatctgta tccctcactt
    56581 tcttcttaag taagacactt tttttcattt ttttcaaaca aaacaatgct attttcttcc
    56641 atttttctat atactaaaag ggaactcatt gaataaagga gagaaaaaac atgaaaatcg
    56701 caatagctgg ggccggagca atgggcagcc gaatcggatt gatgctacat caaagcggaa
    56761 atgaggtcct cttgatcgat cgttggcctg ctcacattga agccattcgt acaaatgggt
    56821 tgattgctga ctttaacggt aaagaagtgg tcgcaaaact gccaatctat tcaccagaag
    56881 aaatcatcga aagcaacgaa cacgtggact tgatcgtagc attaacaaaa gccaatcaat
    56941 tagatgatat gttttgttcg atccaatcca ttattactga caatacttat gttttgtgtt
    57001 tactaaatgg attaggtcat gaagatgtac tggaaaaata tgtgccaaag aaaaatatct
    57061 tatttgggat cacgatgtgg acagctggtc tagctggtcc cggaaaagtc acattgttag
    57121 gtgatggaga aatcgaacta gagaacttgg aaccagaagg cgaagcattt acaaaaaaag
    57181 ttgtagaagt ctttcaagaa gcaaatttaa atccgatcta tagccataac gttcgttatt
    57241 ccatttggcg aaaagcttgt gtaaatggaa cattgaatgg tttatgcacg attttggatt
    57301 gtaatattgc tgaactaggc gcgcaaaaag cggcagagag catggttcga acaatcgtat
    57361 ctgaatttgc ttctatcgca gcaaaagaag gaatcatact agatcaagaa gaagtgtacc
    57421 aacatattgc ttctacttat gatcctgaca acatcgggtt gcattaccca tctatgtacc
    57481 aagacctgat caaaaaccat cgtttgactg aaatcgacta catcaatggt gccatttggc
    57541 gaaaaggaca aaaatatgat attgctacac catattgtgc ctttttgacc caattagtcc
    57601 atgcaaaaga aggaatcctt ggcgcagaat aaaaggctct ctgatgagaa tcagctgaat
    57661 cagcagctgg ttctcttttt ttaagcccaa taaaagatca aaaagaaaac acaactctca
    57721 tgatgccata agaattgtgc ttgtttgttt cagtacataa tctcttcaaa atgtaggttt
    57781 tttatttgtt ttcaacagag gagaggtcat attcgtattg ctcataaata gtggaatcgt
    57841 tagtgataaa tcgttttgcc caattttctg catcataaaa ttccaatagc tctgatagga
    57901 ttggcttaaa tggtgtatgc agaaattccg gtaattcatc taaatcacgt tctcgaagca
    57961 aaaaaatatt ttcaggacga taaaaatgat aatgagcaat cgcttgatta tccgtcacta
    58021 gtttcttttg aaaatacatg gattcaaatg tccgcaaagt cactccttgc tgaccctccc
    58081 gcaacagttc cagaatcccg cgcgattccc ctgttttttt caggtactct tcataagtaa
    58141 gatatccagg ttgttcattc cctcgatgtg gaagaatgaa atagttggtc gtaacatctc
    58201 tttttataaa ttcctgctta tagctttctg ctcgttcttt tctcccatta ttcgttgcac
    58261 caaaaaatag atccgtcttt ggttcgctag aagaaaaatt catatgtttc gaataaaatg
    58321 aactattatg tttcagccca agttcttttg cttccaaaaa atcaaaatga taaatctcat
    58381 cgattgccgg ttcatcttgt gcctgcttca gcatcgcctc gtgttctgct ttgaagtgat
    58441 tccaaaaaaa taacacaatt tttgcattgg taaatgggcg cacgcgtcga gccatctcca
    58501 tatcaaatcc ataatctaaa aaaacgatca gctgataatt tgccaactgt tgtctagctg
    58561 atttaatgaa ttccgactgt agtaaatctt ttccggacca aacatctaaa gagcggatgg
    58621 aaggcaaaaa ataaagtgat ttattttttg caactagcag tacgtcattt ttgttcatct
    58681 tttccgcctc actttctctg tcactttttc ctatgatagc ctgtttaaat agtaaaaagc
    58741 cagtaaaacg tttcctatat ttgtatgaaa atttaacatt tgtatgaaaa tatgatgaaa
    58801 taaatcattc ttctattaaa attcgcctaa aagttttctg aatagttgta attgtctgaa
    58861 aatttgttat cattagtcat tgttaaatat tgctatttat tcttaatata aattttgatt
    58921 gtgaatttaa aagaaagagg tcatttatgg aagataaaaa attgaaaaaa caacttagct
    58981 ccagacatat caccatgtta gctttaggtg gagcaatcgg tgcaggtcta tttaaaggaa
    59041 gtggcgaagc gattgggatc gccggccctt ctgtattgat tgcttttttg attggtgggc
    59101 tgattttata tatcgtgatg aaaggtctgg gaaaaatcgt tttaagcggt ggcgacacgc
    59161 atcacggatt atctggtttg atacgccctt atctaggtgc tcattctgct gattttactg
    59221 attgggtcta ctggtctatg tggattatca atatcatcgc tgaagctgtt gcagctgctt
    59281 cctttttgca gttgtggttc ccgcacattc cagcctgggt atttgttttt atgttggctg
    59341 ttttaactac gatcatcaat ctttattcgg tacggttatt cgcagaaaca gaatattggc
    59401 tggcttttgc taaaatcagt gtcattatct tactgatcat ttttgctact tatcttgtcg
    59461 gtcagcaaat gttgggcaca ggcgttttcc ctacccttca gcaattgact gaccatggtg
    59521 ggtttactcc tcatggtatg aagggaatca tcagttcttt gcttgtagtt atctattctt
    59581 acggcggttc tgaactgatt gctatcacgg taagcgaagc agatgatcct aaacgtgcga
    59641 ttcctaaagc aatcaaaggt gtcatgggaa gaatcatttc cttttacatc attcctttgt
    59701 ttttgctttt gattcttttt ccttggaata ctttagcagg cacgaatgtc agtccttttg
    59761 tgatggtatt tgaaaaaatg aatatcccat ttgcagcgga tatcgtcaat tttgtgattg
    59821 tccttgcttt gttctcatct atcaattcgg gtgtgtatgc atcttcaaga attttgttct
    59881 tccgtttgaa ggatcgaaaa ggttcctcta gaaaactagc tgttttaaac aagcatcaag
    59941 taccgcaacg tgctgtttta ttttgtacca gtgttcttta tcttggtgta gctctttctt
    60001 attttgtcgg tgacaaatta tttggctatc tggcaggttc cctttcgtat acagtattat
    60061 tgatctggat cattatcagt gcggcatcct ttgtactggc actaagaaaa ggaacattat
    60121 gggataaagg aatcagcttt tttgcattag ctgtcttagg attgattttc cttggtatcc
    60181 tgttcacgaa ctccattggg gtaactgtat tgactggcct gctttacctg ttcatttatt
    60241 tcagttatca aaaaaagaat gatgcgttcg tattgacgaa tgaatgaaat cgatagaaaa
    60301 ttttatttta tttatgtgga atagatggag ctattgaaga aaggagttgt gacaaaagtc
    60361 ttgttgcaac tcctttttcc gaataaacag tctcatgacc tcttggtaaa cggtgttcaa
    60421 aaaccctctg tgcaaaataa ttgattgttc tccatgctca tgacatgata gaagaaagga
    60481 atgaaaaaaa ggagtttgtt ttaaatgaaa aagtattgga agtttttgtt gatgatcggt
    60541 gtttcaacgg tagttatgtt tggtatgatg tacttgaatg tctatgcgct cgatcatatc
    60601 ttcttcagtc gtacacgagt attcatggcg ttgatgatgg gtgcagtcat ggcagtcatc
    60661 atgctgttgt tcatgtggaa aatgtatgaa aacaaaaaga taaatgttat gatcttagcc
    60721 gctagtcttc ttgtttttgc cggttccttg tttatggtac gaagccaaac tactgtcaac
    60781 gacacagctt ggatgaaggc catgattcct catcattcta tcgctatcct ggcaagtaaa
    60841 cgagctgatt taaaagatcc tgaagtaaaa aaattagcgg aagaaatcat tcaggcacaa
    60901 gaagaagaga tcgacaaaat gaaaaaaatg atcaaagaaa tggaatgacc attatccgtc
    60961 caaataaaaa aagaggatgt tccagaagtt atcagcttca agaaataaga agaagctact
    61021 tctggaacgc cgtgaataag gggttgtgaa aaagctgccc tgcatcaagt aataagaaca
    61081 gccaaacaaa aatagcttct cctatttttc gtttggttag gcttattacc gcagatgcaa
    61141 gcttttgaac accgtttatt aagaggttgt aaaatcagcg ttctgacctg agtattagag
    61201 agacaaatgg aaaaatagtt cctcatattt tgccattttt tgagctaata ccgagggtca
    61261 gctgattgaa caccgtttat cgagaggttg tgaaaaagtc gcttagtttc gcgtattaag
    61321 aaaaattttg tgaaatggct ttccacattt ttgtataaat ttggcttaat accgagaaac
    61381 tggcttttga ataccgttta ttcgtaaaag ggattgtgac aaaagtcttg tcacaatccc
    61441 tttttatgtt tttattgttc taattgcgct gtcttgctta ctgcttcttg cggtttcaca
    61501 aatttttttg agattcccca acctgtgaag gcactgacca tcgaaaacac aggagaaagc
    61561 aaactgaaaa atacgaatgg caagtaagtg agtgtaggaa taccaaatgt acttgctacg
    61621 aaacttccgg caattcccca aggcactaag tagttgatta ctgttccacc atcttctagc
    61681 gttctaccta atacagttgg atcaaatcct gctttttcat aagtttcttt aaatgcatta
    61741 ccaggcagaa taacagatag gaattgttca ccaataaaaa tatttactcc gatacttgtc
    61801 atcaatgttg taaaaatcaa atttggtgtg ttcgtcatct ttcttgatac tcgttccatc
    61861 acggttgaga tcaagccaaa ttcgatcaac aatccaccta atgacaaagt tagaataatc
    61921 aatgacacag taggcatcat actttcgatt cctccgcggc taagcagtga atcgatttgt
    61981 tggtttccag tatttgaaac aaaccctgat tcgatgaccc cagccaactt cgttaaggaa
    62041 gtttgtgggt tttgaataaa aatcattcct actgctacag cgatattcaa caaaatcgtt
    62101 aaaattgccg gcaccttttt ccatgcacac agtaacatta aaaataaagg aatcagtgac
    62161 cagattgaaa tagtaaagtt tgcttctaga acatcagtca cttcacgaat agatgaaaga
    62221 cttgcggctt tacttgtgtg tcctaaaatc atgaataaaa agaaagaaac aacaaatgcc
    62281 gggacagttg accacatcat atgcttgatg tgtttgaaca aatcggcatc aacaatagct
    62341 gctgctagat ttgttgattc ggataatgga gacatcttat ctccaaaaac ggcacctgaa
    62401 acaatagctc caacaaccag cgctggattt aagcctagtg ttgtcccaat accgaaaaat
    62461 gcaatcccaa tcgttgacat aacagtaaag gcactcccta cagcgctacc tacgattgca
    62521 cacacaacaa atacagaagg gacaaaccac tggacactga tcaatttgaa cccaatgacc
    62581 attagagttg gaatgatccc tgcttgtatc catacagcaa tcaatgaacc gactaaaata
    62641 aaaataaaga ttgggatgat tcctggtttg atgccattga tgattccttc gtgcagccaa
    62701 tctgtcgggt atctttttat cactgcatac aacatgacca ttccgatcgc tgctaagatc
    62761 gtgatattag gtgagacctt taatccgaca acgccaatcg caatgcctaa aacaataacc
    62821 attaatacaa gtgttgcttc taaaaaactt ggtgttcctt tttttcccat gataatctct
    62881 ccttttttag ttgttcttat gttctaaaaa agttaagata tcggattact ccgccgcaat
    62941 tcatccgcga ttcctccttt ataaaaataa aaagacctgt tttaaactaa ggacgaatga
    63001 ctccgcggta ccaccttaat taaaaacaga tctgtttttc actttcaaac ttttattcaa
    63061 atgtatggac tttccatgta attcgtcaat taggcttgat cggttcacag cgaccaccga
    63121 ctttctgaac aaaacaccta accgctactg cgtgaaaagt tgacttgtac gaagtttacc
    63181 ttccataaga tcatttgtca atgaaaaaga aaatattttt tcatttttct gaaaattatt
    63241 tttataactt tcacacacaa gtttattttt tactagaaag tagcgccctc ttgttttttt
    63301 cttgctacta tttcttgatg ttcttgcttg attctttcta atagctttgg ctctttcaac
    63361 agatcaagag ctgtattggc gagtagttct gctgcaatcg caatagaagc aaggcctttg
    63421 tcacttttag cagcagcttt gaattcttct gtgtgtccgg caatatatgt ctcagagatt
    63481 gctaccgtag gctggattgt tggtatgact tggctgacat ttcctacatc agaagaaccg
    63541 agacttgttc tttgttccgt ttctatttct tcatctggaa cacctgcttc ttttgcatgc
    63601 tggaagaata agtcatcaaa agaaggagta acgatgacat catcaactgc attttggaac
    63661 aatccaaact caaaagtcgt gcccgtactt atcgcagcac ctcgtacgat attttccact
    63721 ttttcatata ctttatctaa tgtttgccga tttcctgcac gtaaatagaa acgtccagca
    63781 gcgtaatctg gaatgacgtt ggcagctact cctccgtctg taatgatccc atggatattg
    63841 acatcttttg gcaattgcaa gcgtagagcg ttgattccat taaacacttg gatcaatgct
    63901 tccaaagcat ttactccttt ttcaggtgct gctgctgcat gggaagcgac accgtaaaat
    63961 ttgatgtcga ctggatcatt cgctaaagat tctgtcgttt tcccataacg aaaagctgga
    64021 tggacgcata acgctacatc gacatcctca aaaaaacctt ctcgaacaaa gctgccttta
    64081 gctgatccgt tctcgccccc ttcttcccct ggggtgccat atacacggat ttctccacca
    64141 gtttcatcaa tgaattgctt cactatgctg gcggctaata cggagtaagt accaaacaaa
    64201 ttatgcccgc atgcatgacc aatacctggt aaagcatcga attctgccaa aaaggcaatt
    64261 gtgggaccgg gtttattgga aatataacgt gcatcaaagg ctgttcggtg tccagctact
    64321 tctttttcta cccaaaacct ttctttttct aattgtttaa tcaacgctgc tgaggaataa
    64381 aactcatagt tacttacttc aggatgttcg tggatatcta gagcaagtgc ttgatattct
    64441 ggtaaacgat attggattag atccttcaat tggtttgttg agattgttgt tgtcataaaa
    64501 aattcctcct atgctagtca tttttcttat tttctcccga atgtttccca tgcaggcacg
    64561 cttgatcctt ttgatgtttt ctcgattact ttgactgtgt cttctgtttg ataagcgtct
    64621 actatttttt gatacgtttt attgttttca tcttcttttc ttgcaacgat gatattcaca
    64681 taaggacgtg catggtcatc cactggttct aagaagatgg catcagaagc aggattaaat
    64741 ccagcatcta cagctacacc gctattgatc actgaaatgt ctacatctga caaagcacgt
    64801 gctgtttggg aagcatctaa ttcagaaatg tctagatttt ttctattctc ggtaatatca
    64861 gaaacagtgg gcgcttgtcc ttttgcctta tccactttga tcaatccagc agtttgcaat
    64921 aacagaagag ctctgccgcc atttgtaaca tcattaggga ttgctacttt tgctccgtct
    64981 ttgatatcag ctacatcctt caaagtgtta gaataaattc ccagcggtgc attgacagta
    65041 tttccgatcg atactaaatc agttccgtgt tctttattgt aattgtctaa aaagaattga
    65101 tgttggaaag aattcaaatc aatcgatcca tctgctaaag ccacatttgg ttgattgtaa
    65161 tctgtaaatt tcacgtattc caaattaatg ttctcctttt tcaaacggtc tttcacgttg
    65221 tcccatacat ctgtatcttc tccaataatc cctagtttta cgatagtttc ttttttgtca
    65281 gttgtatctg cttttccttg gctacaccct gccaaccaaa taattgctac aaatgtaatg
    65341 actacaaaac gaataatttt tttcattttt tctcctccac tttcaatgtg taattttttt
    65401 aatcagttga ttactgataa attgacttaa aaaaactaag attagaatca ataatgtagc
    65461 cacaatcgtt acatctgttt ggaatcgatt ataccctctc gatatagcaa gattccctaa
    65521 tccgcctgca cctactgctc cagccatggt agtcagtccg atcacgttga tgatagtcaa
    65581 cgccgagacc cgaatgatac caggcaaacc ttctaacaaa tacacacgta aaatgatacc
    65641 gattggactg gttcccatcg cttctgccgc ttcgatcacc ccaggatcaa cttctagcag
    65701 tgcgttctcg atttgacgag caaaaaacgg aacaactcca aaaatcaatg gcactaaagc
    65761 tgctttcgca ccaatcgtcg ttccaactaa gaaacgagta gtcaatgcta aaagagaaag
    65821 caagataatg aaagggatgg aacgaatgat attgatcagc ttatcaagta tttcaaatag
    65881 cagacggtta gctagtaatc cattagggcg tgtcactact aacgtcacac ctaagatgat
    65941 tccaatcatc ccgccaatga atgctgtcca aaaagacata tatagtgttt gcttcgtcgc
    66001 ttcgacaaat tcatccggaa tcaaataaac attgggcaaa tatgttttaa agaaatcagt
    66061 cattttatct tcctccttcg atcactttga tacgactatc taaatcgttt ttttgtaaaa
    66121 tatttatttt tacaccagat ttgatcaaat aatccaatgc ttttttccgc tgtttggttt
    66181 ctccagctaa agtaacgatc aaactcccta acggcgtttc ttgtaataac tctacattgc
    66241 catataaaat attcgctgtt acttgatatt tgctgtacag atgagcgatt agaggttcgt
    66301 tcgtctgatt tccaatataa cttaattcca ccagccattt attggcgatc tgatcggcaa
    66361 aagcagaatg ggcaatgatc gtttctaatg cttggtcaag atgagtagct gttcgaataa
    66421 aatctttggt caattcttct tcaggattgc tgaagatctg gatgctgcta cctttttcaa
    66481 cgattcttcc atcttccata accgctacct tgttgcagat ttctttgaca acttgcatct
    66541 catgagtgat caggacgatt gttaaaccta actggcgatt caattttttt aacaatgcaa
    66601 ggatctgaag ggtcgttttc ggatcaagtg cactggttgc ttcatcacat aataatacct
    66661 taggttcatt cgccaaagct cgtgcgattg ctactcgttg tttttgtccc cccgacagtt
    66721 gtttaggata agcagatgct ttttcttcca aaccgacaag ttccagtagt tcattcactt
    66781 tttgacgacg ttcctgtttc gattttccag aatactttaa agaaaaatca acgttgtcaa
    66841 aaatagttcg gctttccatt agattgaaat gctgaaagat cataccgatg gcctttcttt
    66901 cttttcgcaa ttctttggga gagagctgac tcagattcgt ctgattgaca atgacttctc
    66961 ctgctgttgg tttctgcagc aaattcatca cacgaactaa cgtacttttc cctgcacctg
    67021 agtaaccgac gattccataa acatcgcctt tttcaatcgt taaatctaca gaatctactg
    67081 cctgtatctc tttttctttt tgtttgaaac atacagaaac atctcgcaat tcaatcatta
    67141 aaattcctcc ttatctaaaa aaagcgtcct caagaaaatg aaaatgtcat tttcttgagg
    67201 acgctttttt gcgtgttacc acctcatgtt caagctgtgt tcacacacaa ctcctcttca
    67261 agtacgatca tactctagca agatatcggt cgcagccgtc atcgccttac atctatgctc
    67321 gggatgaatt gctcgatggc cattttccaa tagtcgttcc ttgcttcttc tcagctaccg
    67381 aagctctctg tcaaaggttc ttctatcgta cttaccattt caatgcaaat aatattcaaa
    67441 aaaaaagtcc ttttactaac ataaactatg tcagtaaaag gacgacgtat cgcggtacca
    67501 ccttttttcg gaagtttcct tccctcaagc ccaacatctc aaaaagagag attggcgttc
    67561 gttttaacgg tcgaacagtt ccgaatttgc ctacttatcg acaaattatt ctccaaggcc
    67621 attttcagct tttcttactt gactcttctc accagccaga gcctctctgc aaagtttcca
    67681 aacttacttt ccttttcaac gaaatcgata ttttgttgtt gggattaatc tacatgagga
    67741 aaactgaaaa gtcaagtacg aaattcaaat tattttttct atatttattt ttctgttttt
    67801 ttatttaaca tttcaataac agttcgaaga tcttttcctt ccgcaagaag tttcaatttt
    67861 tccttttctt cgacggtata atttcggaca aaactggaat caggtatcaa aacaacgcct
    67921 aatcctgctc gtgaagcagc tgttgctcct actaaagaat cttccactgc aaaggctgaa
    67981 ctagcttcta atcctgttcg ttccaaagct gtcagataag gaatcggtga aggcttgttc
    68041 tccgacactt cgtctccgaa tgtaaacgtg tccaagtaat cagctaattt aaagtgatcc
    68101 aagatatctg ttgctctttt cgtaacagtg gtcgtagcaa tgcctagttt catatgacgt
    68161 tcttttaagt ctgccaatat ttcttttgca tatggtttta agtggatggc tccgcttgtc
    68221 agctgttgat aaaaatattc ttcacgcttc gctcggactt cctgtacttt ttcagggcta
    68281 cctgctgctt tcactaaaat atcaaaactt tgtttccagt tttttccgcc ccaagcgtca
    68341 acgatttctt ttgggatatg gatatcaaat tgctgaaatc cccaaagcca gccatcacga
    68401 tacgtttttt ctgtgtcaac taacaaacca tctaaatcaa atattgcacc tttcatctat
    68461 acattaatcc tttccaaaac aatacacata gtttagcacg actggtccaa aaagaacaga
    68521 agcaaagaac cagccttctc gtttataaga gttcttggaa tcgacggata tagattttct
    68581 tcacagctgt cacaagcgcc agataagcga tgactgtagc aaataaccat aaccagtaat
    68641 tgccaggaag tggcatcaag cctaattcag caccaaaact tgtaaaagga aggacagaac
    68701 cgacaataat tcctaatgta gtgataacaa acatggcaaa tgttgcgttg ctttggataa
    68761 atggtacttt cggtgtacgc agtgcatgga gcactaaggt ttgtgtccat agtgattcga
    68821 caaaccatcc tgcatggaat aatgcgatga aaatcactcg ctgtgaacta tccaatgtat
    68881 ggaaacttcc gcccactaca gcaggacaaa taacaaaata catcaacaag taagtagtaa
    68941 tatcaaatat cgaacttgtt ggaccaaagt aaaccatgaa ttccccaata ctagatgcat
    69001 tccatttttt tggctcgtcc aaatattctt tatccatccg atcccatggc aaggaaatgc
    69061 aggaaacatc atagatcaga ttcaaaaaca aaagttgtaa aggcagcatt ggtaaaaatg
    69121 gcaggaacgt acttgcaatc agcacggaaa acatattgcc aaaattagaa cttgctgtag
    69181 ccttgatata tttcatgata ttcccaaaag tttctcgtcc agaaagaagg cctctttcca
    69241 aaatcgtcaa atctttttct aaaaggatca cgtctgcaga ttctttcgca atatccacag
    69301 ctgtatctac agaaataccg atatcagcca ctttcattgc aggagcgtca ttgataccat
    69361 ctcctaaaaa tccgacagta tgaccatttt tacgtaaagc tgtcgtcaaa cgtgcttttt
    69421 gctgaggatt caattttacg aatacttcat ggtcttcagc tacttgtgct aattcatgat
    69481 cactcatttc cgagattttc tcaccggtaa ccaattcatt gatctctaga cctacttgac
    69541 ggcacactga acgtgtaact aattcgttgt ccccagtcag aacttttaca gctacaccat
    69601 gttctttcag agctttcaac gcttgtttcg ttgtttcttt tggtggatca aggaaagcaa
    69661 gataaccaat caaaaccatg tctgactcat ctttgactga aaattctcca acgacgcttg
    69721 gattggtctt ttgtgcgaca ccaatcactc gtaagccatc ttcattaagt gactgtactt
    69781 ttgcaagtac ggcttctttt cgttcttttg ttaatggtgt aacagtaccg ccaagatcaa
    69841 taaatttaga aatgttcagc atttcttcaa tcgcgccttt tgtgatcatt tgtgttttac
    69901 cagctggatc agcaaccaca acactcatac gacgacgttc aaaatcaaaa ggaatttcat
    69961 ccactttttg ataattgatc ttatctgtat ctaaagtttc tgttgcttca tcaatgatag
    70021 ccacatctaa caaatttttc agccctgttt gatagtagct atttagatac gcatggcgca
    70081 aaacacgatc atcttcattt ccttcacaat ccatatgata ttcaagaatg attttatctt
    70141 gtgtcaatgt ccccgtttta tccgtacata acacatcgat tgcaccaaag ttctggatgg
    70201 cattcaaatt tttgatcact gttccttttt tggccatcac acttgctcct ttgaccaaat
    70261 tcgtcgtaac gatcattgga agcatttcag gtgttagacc aactgctaca gatagtccaa
    70321 aaagaaaagc ttctagccaa tccccttttg taagcccatt gatgacgata actgctggag
    70381 ccatcaatga cataaatttg atcagtagca tggatgtttt atggatgcct aattcaaagc
    70441 ttgattgaat tggtttttca gatagcgttt ctgctacatg accaaatagt gtttcatttc
    70501 caacagaaac aatgattcct tccgcacttc cactgatgac attacttccc ataaagacaa
    70561 gattttcgta acttgtttcg ctttgctgat cgtctccaca tactttcgca tgcttttcta
    70621 ctggatagct ttcccctgtc aatgctgctt gggaaatgaa taaatccttt gcggacaata
    70681 aacgcatatc cgctggtatc atatcccctg ctgaaagccg aacaagatct ccacagacga
    70741 tttcttccat aggaatctct gtgtactttc cattacgttt tacagctgcc gttactttca
    70801 caagtgattt cagtttttca gccgcttgat tggaacgtac ggactgaatc aacgtcattg
    70861 tcccgctgac gataaccata gtgaagataa tggctacacc gaaaagatct ttatctccag
    70921 gagctgctaa tacatattcc gtgatgaatg aaataattcc taatgcgatc aacactaatg
    70981 taaatggcgt gatgtatgct ttcaatattt ctacaatgaa tggtgttttt ttgccatatg
    71041 aaatcgcatt ttcaccgtaa ttttctcttg aacgttcgat ttgttcttct gtcaatccat
    71101 ttgctgatgc atggaatagt tcaaataatt cttgtttcgt ttttccagca aaagctgcat
    71161 agattttttg tgtatctttc tttttttcca tctcaatctc tcctttgtgt ccaaaagaca
    71221 gctgttctcg ctgcttttgg tctttagcta ttcatcggat cgatagagaa aaaactgaaa
    71281 ggggctgaga acagatagat aatagccctg gcctttcctc tagatccttg tttttcgaat
    71341 gactgtcatc catttgttct catctccttt actaagtaat tttaattcat gacttccaat
    71401 catttttcga atagttattt ttccaattag accacctcct ttttattttt caccgatggg
    71461 gatttgcggc aacaaaaaaa cctctcgcca aatactcagc gaaaggtttg aaaaagcata
    71521 ttaaaaaaag cttctcagat ctcatcgttg agttttgaca ctgtacaacg taaaaagcag
    71581 atacctgctt ttagctacct tatgaaaagc cttatctcga caattcctgt tctacccatt
    71641 ggcgtctctc gacgtttttg ggcagtagcc tatgtttgta taggagcctc acctaacaaa
    71701 tcttattcgg ttttccttcg ttaatataac aactaaaaaa gaggatgtca aatcaatttt
    71761 ccatgttttt catacttttt ttaaaataca cacgttatat tcctgtctca cgcggtttta
    71821 tttgtctcat tttccacctc ccgctataat agaaatatag taggaaacga ggtgctgtta
    71881 tggaaagaac acttgttatt atcaagccag acggcgtgag acgccattta gtcggaagca
    71941 tcatccaacg ttttgaagca aagggactgg ccattgctga aatgaagttt gaaactatga
    72001 ctcctgaatt agcaaaagaa cattatcagc acttgactga gcgcagtttt tttgatgaac
    72061 tgatcgatta catgacttcc ggtcctgtcg tttatcttgt gctggtcggc gaggaagtga
    72121 tcgatatcgt ccgtaagatg gttggagcaa caaaagctgc cgatgctgtt ccaggtacga
    72181 tccgaggaga ctacgcgctg ccggggactg aaaacatcat tcacgcttct gattcccgtg
    72241 atgctgcggt aaaagagatc gcccgctttt tcccgccatt cgatataaac aaaccgtctg
    72301 aaaaagcggc gaagtgatac aaattctaaa ctgctggtct agttgctggg ttcagcaatg
    72361 gccagcagtt ttttctctaa ggacctccgt tgattctttc ctaacatata ttcgagcact
    72421 gtgaagaatt cttggtagtc tttcgtcttt tcttccccta aagcagcaga aatcaatctt
    72481 tgataataat ctgccatcaa tgtttcatag atcactgtac ttctttcttt atgtgctaag
    72541 ctccgtttca tatcttcatt cacactacgt gcctttttca accgaccatt ttctatataa
    72601 aacgaagtca ggttcattaa aaaagtaaag agatactgct catgattgtt caactgtgct
    72661 aatcgtcgca ttcttttttt gattttcaaa taattgttct caatgaaccg atcactgaat
    72721 atccaaggaa aatcagctag aatagatagt tcaaattgac catagtctgg tatctgcatc
    72781 aagtattctt caatgattcg gcattcataa cgtaaaaatt caaattctgt ctcagatact
    72841 tctgtttttt cgaccatgtg aagattcaaa accaaataat acagatcttc tgttttctta
    72901 aaatgcctac ggttattgct gatctcttta taaggatcaa agctgtcttc ttgtacccga
    72961 tctagcattc gtcttttttt ctttaacttt attggttcat ccagctggtt tcgcatccat
    73021 tcatattctg caagtgtcat gttcattcgc tctaaaaatg atctcaatgt tacaaatgac
    73081 atttttttca ctgaatttgt ctcaatcccg actagagaag tcttaaaaca gattccttcc
    73141 gctaattggg actgtgtcaa cttcttgttg actcgaagtt tcttgatcaa ttcaccatca
    73201 tacataatag ttctcctttt taatttaaat ttttccacat tcaataaata gatacgttaa
    73261 aaaggaaaaa tacacgaaaa aaataaaaaa atgttttttt cataaaaaat accaaccttc
    73321 aagcattaga atgttgtcta actactgaag gttggtttga ttgtttattg attatttttt
    73381 tgctgttcaa cgtctgttct tgttactgga tataagttgg ttgttgtttt attaccattt
    73441 tttgaaaaga cacttgtcga atgttcgcct ttttgctttt cgattgcttc attacgttcc
    73501 gcttcatttt tatagtcata ttttttcgga tcaatcgtct caaatccgtt tggcacataa
    73561 aaccgcaaga gattttcctg attcagctta tctgaaagac ttaacgcagt cttgactttt
    73621 tcctgatctt tggagatttc ctcatcgatt cctgctgctt tcgtatcgat gatttctcct
    73681 gtctgattat tgtaagcttt tcctcctagg acggtgtatt tgggtgtcac aaagttccca
    73741 tttcgaaaag caactacttg atcatgctga gaagataata agtctgtacc aaaatgaaga
    73801 taatctttat catcgattcc caatagatgt agtaatgtcg gcaaaacatc gatttctcca
    73861 ccgtattcat gattgactgt ccctttagta taaccaggca tatggatcat caatggcact
    73921 cgttgcatct gtgcgttgtc aaattcatcc catgtatctg gatctttacc aagagcgctt
    73981 gctaaatctt tattatctgt attcgagatc ccaaaatgat ccccgtaaat cacaaagatt
    74041 gaattttggt aaataccaga ttttttcaaa tacgtaaaaa attgttccaa tgattgatcc
    74101 agataatgtg ccgttcgaac ataattatct actgtgctat tgccagtatt caaagatgga
    74161 aagtcgaaat tcttgtcatc cgtataataa ggcgtgtggt tggttacgga aagaaatttc
    74221 gtgtaaaacg gctgttgtag atgctcaaga tattgggcag attctctgaa taaatcttta
    74281 tctaatatcc cataacctaa cgtttcgtcg gattcatcaa aataagatcg atcaaagaaa
    74341 ttgtcataac ctaagttttt atatacatga tctctattcc aaaaactagc tacattccca
    74401 tggaaaacag cgcttgtata gccttgcttt tgtccaagga tcgctggtgc ggcttgaaag
    74461 acattgtctg acccaagttc tgtgaataat gagccttgag gtaaaccaaa tgtgccagtt
    74521 tccaacatat tttcagcatc acttgtcttt ccctgtccta cttcatgaaa gaaattgtca
    74581 aagctgatcg ttgcttgatt ctggaaaata ctatttaaaa acggtgtgac ttcttgtccg
    74641 tctaccttca tattaatcaa aaactgctgg aaactttcta aatggagaac gatcacattt
    74701 ttccctttag cgatcccaaa tgtttcggga tttggctctg cataatgttt ctttgtataa
    74761 tctaaaactt catcaatccc attactgctt gcatgcgcgc gaacactgct agtcattcct
    74821 gttttgattc cgtcataaat agtatacgca tcgattccta gatatttgac aatatatgaa
    74881 cggtcaaatg ttcgctgcag caattgtgga cggttggctt cgctcagcgc tagatttcct
    74941 gaaaaaataa gccctgaaag acaggtaaca gcgatagcca tcggtttgcc gacagggttg
    75001 cttttgatag gtattttctt gaccttcaac caaaccagta gcccaatgaa cacagcgata
    75061 tccagccagt agatgacatc atggggcttc atcaaagaaa aggagcttcc tgacaatcct
    75121 tgcgacactt tcgaaaagcc taatacagat ttgactgtaa tgaaatctgt gaattcccga
    75181 taaaaaataa tattcaagta caacaaaagc gtatttaaaa tatcaatgat caaaagaata
    75241 gctaacgctg gctttggctt tttaatatac aaagaaaggc caaaaaacaa taaggtagtc
    75301 gcaattgggt tgatccacaa gataaagtac tggatcgtac cttccacacc taatgaaaaa
    75361 tctgcatagt aggcaatgat cgtcttcagc cagaaaaaga aaacagctgt caaaacgatt
    75421 gctaaacgat tttggcacaa ttttttaagt tgtgtcacgt atatcacttc tctctattca
    75481 cattttttct tattttgctc ctgaaaaatg aaaatttcct aaaaaagttg ttatcttaag
    75541 atttttttat tctttctaaa gattattccg tccacttttc acagcataaa accgctgcga
    75601 tgtaagcgat taaactaatg aagagataaa agtcttgtgg tgaccgcttc actccacggt
    75661 attcaaaagc cagtttctcg gtattcgtac aaaaaaagag gctgtgacaa aattcttgtc
    75721 gcagctcctt atttcttgat gcaggacagc tttttcacaa cttcttcctt aaacggtgtt
    75781 ctcctgccaa ctcctcggcc acaagtcaca atatttataa aacatgagaa gctgtttttt
    75841 gaaattgttc cttgtggctc agagttaaac ggcaggctca agacctcttg atacacggtg
    75901 ttcaatcagc tgaccctcgg tattagatta tgtcaggacg ctaattttac aacctcttgg
    75961 taaacggtgt tcaaaagctt gcatctgcgg taataagccc aaccaaacga aaaatataag
    76021 gagctatttt ttgaaattgc tccttgtggc tcagagttaa acggcaggct caagacctct
    76081 tgatacacgg tgttcaatca gctgaccttc ggtattagct caaaaaacgg caaaatatga
    76141 ggaactattt tgccgtttgt ttctctaata ctcaggtcaa aacgctgatt tcacaacctc
    76201 tgtttttcat tgtccatagg attgatattg tccttgtgat gactcattcg taataattga
    76261 ggcttgattt tcttcacttc ccgttatcgt ttgtccactg ccagaatctg aaggacttgt
    76321 tcctgtcgac tcgttttttt gagaagagac agttgttttc ttgacttgtt catttgtctt
    76381 tttccattcc gctaaacgat cggcgaccac ttttttgtct actttttcag aataagcggt
    76441 gatcactttt ccatttttca aacgggctac tttgtcgcca tcatgagtca aaagcaaaac
    76501 ggtcaaatgc ttgtctttaa attgatattg tctgagagaa atcgcactaa gtacgtcatc
    76561 gatattaata aattgatttt cttcttttcc ttttggcaaa taaatgtcca attcgccttt
    76621 ttcgtaattg gcagttattt tatactccgc ccaccaataa gttgagaatt cttttttgaa
    76681 attatctact gattctttgc ttgctacgat tttttctgtt tctttctgag caagatctgc
    76741 tgtcattttt cctgaaaatg ctgcggataa aataagcagt aagaaaaaac cgaataacca
    76801 aaagagaaga aacggtcttt ttttcctcat gctttcctcc actcctattt aattttgact
    76861 attctattat atacaaaaaa tgaaatagaa agacaaaaaa gttgaaaaag atcgtaaata
    76921 attgaacttc tttttcacaa aatggtaaga atggagaatt tcacgcattt gctctcaact
    76981 attctttctt aagcctcaaa tccgttttta tctgatacgt ctttgaacca atgacccgat
    77041 tttttgattg ttctttttcc atcttgtgct aagtctactg aaataaagcc atatcgattc
    77101 ttatatgcat tggtccacga ccagttatcc atacatgtcc acatatgata gcctaaacaa
    77161 ttggcacctt cttgaatggc ttgatggaca tatttcagat gagattggac aaattcgatc
    77221 cgataatcat cgtggatcat gccatcttct ttgataaatc gtgcttcgtt ttctacaccc
    77281 ataccgtttt cagaaataaa gcagtcgata tttccataat gatctcgtac attgatcaaa
    77341 atatcataga ttccttgttc atagatctcc catccgcgat aaggattcat tttacgacca
    77401 ggcatttcat aattgtcgaa ataatcctca ggcattggac cgtttttagt atcgattggt
    77461 gtttcttttg cttttacccg gcgtggctgg taataattga tacctaaaag atctactgta
    77521 ttttctttga taaccgtcaa atcctctgca tggatcacag gcatgagatc aagttctttt
    77581 actatctcaa tcaattcact tggaaactcg ccttttacag ctggatcaag gaatgaacga
    77641 ttgaagaacg catctgctat ttgcgctgct ttaacatctt cagggtttga ttcgtctctt
    77701 ggatagcttg gtgtcagatt caagatgata ccaataacac caccttgctc catttcatgg
    77761 taagatttga tggctaacgc tgaagccaac gcttcatgat agccaacttg gatcgctttt
    77821 ttcatatctg actcttctgg ataatgccat cgatataaat aacctgcttc gactggaacg
    77881 attggttcat tatgagtaaa ccattttttt actttcgaac caaacaattc aaaacaactt
    77941 ttggcatatt tttcataggc ttcaaccgtt tctcggttca accatccgcc tttttcttgc
    78001 agatacatcg gcatatcgaa atgatacaga ttcacaaagg gttcgatacc gttttcaatc
    78061 aactcatcaa aataacgatg atagaaacga acggcttctt cgttgattgt tccagattca
    78121 tcaggtatca aacggctcca ttggatagat gttcgaaatg aattatgccc agtctgtttc
    78181 atcaactgta catcctcttg atacttcgta taaacttgcg aggttttttc aggtcctact
    78241 tgatcaaaga acttttgcgg ttcttttttg taccaataat caaaaatgtt ctctcctttt
    78301 ccatcgcctg aaatccttcc ttctgtttgt gggccacttg ctgcagaacc ccaccaaaaa
    78361 tttgctggaa attgatattt tttcatcaaa gcacctcttt ttctttttta gttcgtttta
    78421 gttgattcca tgtatgatat tttccatcac aatcactttt tcattttctt cctcttcttt
    78481 tttgattcgt tttaacagct gttctgctgc tcgttccccg attttatctg ttggtggcgt
    78541 gatcgtgatt ttcggaagga tactcagatc gtttttatct aaataatcat agtgactgaa
    78601 cgcaatatcc ttcccgattc tgacaccttc ttgattgaaa cattcgatgg caccaatcga
    78661 catattgtaa ttgctgacaa aaatagcagt tgcccctttt tctaataatg cttttgcccc
    78721 gtaatagccg ctttttctag aatagtctcc tgtaaagacc tctaattgga tcgatggatc
    78781 attttggacc gcttctttgg ctcctgctaa acgttctctt gctacgtagt ctgtttgagt
    78841 ggcagcaata aatccgattt ttttatgtcc ttgttcacca tgatgagcga tcacttttgc
    78901 tacactttct cgatcattca ctaatattgt atcaatacct gctggtcctt ctggacaatt
    78961 caatgcgata actggaatac tcatttttgt gagcatttca aatccagacc actcttcttc
    79021 ggataagaag acaatcagcc catcgatcac atgcttcatc aggtattcaa ttttttgttc
    79081 aattttttct ggctgatcgg caaacccgct taataataag ctatacccat tttcttcagc
    79141 tactctttcg atccctgaga caacttccga cccaaaacgg ctggaaatcc cgtttatcaa
    79201 aagtccaata gagaagcttc gattattctt caacccttta gcaatgatgt tttctttata
    79261 gtccaacgct gaaatcgctt ctgctatttt tttcatgttc ttttccttca gttgctgacc
    79321 attcaagtaa cgggaaactg ttcccactga aacaccagcc atcttagcca catcacggat
    79381 cgatgccata cattctcact cctgccagtt acatttgatt tctctttctt gttgttcgat
    79441 tatgatgacc gcattctttg catagtgttg cttgtcatca atatccatat aactaaagtc
    79501 ttcagtagag caacttcctc tcactattaa ttatacttaa acaagtattt gaaccggttc
    79561 atttttaata tagcattttt ttaaaagatt gcaacacttt tttaaaacgc tttctgaaag
    79621 tggcggattt tttgcctttt taaaatttta ttctaaaatt tactctattt gtgggtgttt
    79681 tgtgcgtttt tctcttccat ccgtttgaag ttttacattc caatggtata atttctttat
    79741 cctatcaaat gggggaagta ttttgaagaa attaatcgta ctatttattt tgtctgcggg
    79801 acttttgaca ttgactggct gtgatttgtt tggcggctct gaccaatcct cggacgaaac
    79861 aaccgattct tctgtcttaa aagcggaaaa agcagatacc accaacagtg tatatacgct
    79921 aaaagtacgt aaagatatgg atttatccgc gggacagttg acatttacag ataaaaaaat
    79981 ggaatggaca cgcacgtatc agacacaagg aactgattct tctgaatcat ctgaagaaaa
    80041 aacagtgctg acagatatca agatcactac caaagatgac gaatatatta tttcaggaaa
    80101 agaaaataaa aaagaaacaa cagtcatatt tacaaaaatc ggtaattacc gtttgaagga
    80161 tgaggatggc aacatctaca gtctatagtg ccgtctgttg gatcttcttt tgtttctccc
    80221 cttcttttct gctatagtaa agaagcaaga tgattgtaaa ggagacgaaa tggatgatcg
    80281 atagtcctga ttattgtaca tgtaataaca acaaaaatat ccatacagaa tttaatgacc
    80341 aaggaagctt gagcatatgc gacaactgtc acaaactagt caaagattca tttaaaacat
    80401 ttgaatctta tcctgttcaa aattatgtaa aaagtagaag aagataaaca aatccaagca
    80461 aaactcacta tggctgattt ttatgaactt caaactcagc ttcttccttt gatcaagctt
    80521 catcagtaaa acaaacagtg gatcatttca gtttacaaat caaagagtaa agatttattt
    80581 atttcaaata tttgaatata aaataaccaa acgatagaaa ggcttattct acatcacgta
    80641 gtaatttttc tttcccgtcg tttggttttt tatttttagc ctaattcttg accttttgca
    80701 tgctggttat ccgtaaaata ttttccagca ggctttcctt ccaattcagc taatttttct
    80761 tggatctgac ggatcacctt ttttgcatct tctggatttt ctacaaaatc gaatttatcc
    80821 ccatccactt gtattttagg acatacatca aaatcttcat accattgatt atagcgggtg
    80881 ttcaacgttt cataataggt atataacgtc tcatcgcttt ctagctgttc atagtcacgc
    80941 ccacgttttt tgatacgttc tagcatcgtg tccaaagaaa ctttgatatg gaccatcaaa
    81001 tcaggccgtt tttttggagc aacatcatct aactcgttta gcatcgtatc taataagcta
    81061 tcgtactgct gtacttcgat atccgttacc cgacctaaat cagcgtttag atggaacaac
    81121 aggctatctt catagatgga tcggtctagc acattgtcat cgttcactaa agcatttttc
    81181 attgctaaaa atcgcttgtt caaaaagaag atttgcaata aaaaagcgta ctgctcagga
    81241 tttgaataaa agagcggcaa tacttcgtta tcttcgacat tttcataaaa tggtttagaa
    81301 tcaatctctt ttgcaagcat atccgtcaaa ctgctcttac ctgcaccaat cgttcctgaa
    81361 atcaaaatca ctgacataca acccttcctc ttctataagt actcgcctac gtaagtttca
    81421 acaggcaatg tttcaaaatc atattcacgt acagcttggt ctgattttaa atacgtatgg
    81481 agactttgtg taatcatcaa gttcgtaggt accgtctctt cttgtacaat gatcatcggt
    81541 tttttcaaca tagttgccac acctaattcg taagccgttc ctggatcgat tgtttgatgc
    81601 tcaaagtcaa ggatagcaac aacaaattct gcatttgtca gttcttccat atctttttcg
    81661 tatacttcct gcgcccatcc agcgctgaat agttcataat tgctttcttg gtgatgacgt
    81721 ggagagtaga aacttgtgac tgttttgttt tcctccaacg ctttttcgat acgacttact
    81781 cgatcgattt gctcctctga aaaaaatggt cctgctaaat atatttgact cattattttg
    81841 cctccttcaa taataactga tttttaatag atactgctcg taattcattg accagttcca
    81901 atggattgtt ggaaaagatt acttgatcca accatttttt atccataaaa tcctcttttg
    81961 caaaagtttc taataattgt tgcaagccgc tgtaataacc gccaatattc aatattccga
    82021 ttggcttgtc gggcgtcaga ccgattgcta tccaagaaag aagttgtgag aattcctcca
    82081 atgtacctag acctccaggg aaaacgagga cagcatctcc cttttcaaat aataatacct
    82141 ttctttcatc gatcgtttct gtaggaataa atgtagtaac atcttttcca ggcaattcag
    82201 tttcaaaaag cccattcgga tagatacctg tgacttttcc gttattttcc agtactgttt
    82261 tactaatcac tcccataatc ccggagtatg aaccaccgta aaccagttcg atttcttctt
    82321 gtgccatgta ttttcctaac gtttgcgcaa taaatttgta actttcttta ttaccaaaac
    82381 gggaaccgca aaaaacagta agtttcataa aaaaacactc cctaactcaa aagtctatct
    82441 tcattctaca cgtgtttttt taaaataaaa gactagattt tgtagttttt tagtggtata
    82501 taggatagac gccactatat atagtattta gaaaaaaatc atttttcagc cattttatag
    82561 ataaaacaaa aataaataac gtgttttcat cgatatgaaa tgacttactt atagaagata
    82621 ctgggatttc gtcctatatg ccaataacgt gtattatttt aaacaacaaa tacttgtttc
    82681 ttttattaac gaaaaaatca ttttgttctc gtgttatgtt tcactgataa atgatgtttc
    82741 tctaaataaa aaagccgacg aactaaacga tcaaaatttg atcatttttg ttcatcagct
    82801 tctcctaaaa atctttttgt taacgataaa tagctggatt tgtaaaaata tcacttgaat
    82861 cgtcactgct ggaagaaaat tcagtgataa ccgcacctgt tgcgcctgcc tggaactagt
    82921 gtttgatatt gggctcgaac gtgtactgat ctctagcatg aagaataatt tcttttttta
    82981 ctgtataata actttctttc ctttttggaa tagtacagga aagttttttt gtttcctttc
    83041 cttcgacata aggtatacca gaccctttcg acaacgaaag gttctcattt ttccttcatc
    83101 gtcatttcaa ggagggtgcc gatgctctgg acagtttcga tcgctcctaa accaaaatct
    83161 gtatattcga ttctttctaa ctctgattct ttcataccat tcctgtctca aggtacatct
    83221 attgtacttt tttcttgtaa tccattctgc ctctcctaac taattgtcaa atcatcccaa
    83281 gatatgtctt cttcctcttt ttcttcttgg atgatttctg cattcggatc tactggtttt
    83341 ttcaataata aaatggttat tcctgtgaca aaagaaccag ctaacaatgc accaatgaat
    83401 gcccatggtc tggtcatcgt agcgactgca aacattcccg atgccggaat acggctatct
    83461 gcgccccaaa acatgcttaa tccgccacct actgtcccac cgactcccgt tgctatgaca
    83521 ttgcgtgcca agtcgttcaa tacgataggg aaacatccct ctgtgatctg acagatcccc
    83581 ataggaaaag cggtcttcaa tgtatcgatt tcttgacgat tgagtatatt tttacgaatg
    83641 attttcccta agaaataagc gatcgtcaag ccgaatgggg ttaccatcga agctaaaatc
    83701 aatacagtga ttggttcata gattccttct gaaaatcgtg ccacaccccc ttatccagaa
    83761 taaatggtaa tccagaaaca gccgtgtatc tgcggtaata agcctaacca aacgaaaaat
    83821 atgagaagct atttttgttt ggctgttctt attacttgat gcagggcagc tttttcacaa
    83881 cctctttttt tatttatgtt tcataatcaa tatggtaagg atgcagctcc gtatggtaga
    83941 ccgcctccga atattcaatc atttccccaa tttgcgtaga cgatttccgt atccgtttga
    84001 tgccgatctg tgcgtctgtt ttcagaattc cttgttcttc ttctgttaaa aatactgccg
    84061 agaaatcatc agaaaatgag tcaatagtat atcctttttt cgtcagcaaa cgatacaaag
    84121 attctttgcc aaattcttct ctgctgaatt gcatcatttc ttgtggaaga taatgaacaa
    84181 aataaatata aggctgattg ttcaaataat ataagcgctt aaaacaaaca gcttgctcac
    84241 cgaaaaagga aaacaaagga tcttccttct ttatatggac caattgcaaa tccagcgttt
    84301 ctttccggac ttcatatcgg gagttctcca agatttgcgt aaagcttgcc gctttggata
    84361 atcgattgta aggacgattg cttagaaccg tcgtcccacg accacttttc tttgcgacat
    84421 attcatctga tgccagcagt tcgattgcct ttcggacagt gattttgctg acttgaaaca
    84481 gttcttctaa ttcactttct gtcggcaaca tcgaaccgac tggatatttt cctgagaaaa
    84541 tatcttcttt aattttatct gcgacttcca agtatagtac acgtgtcctt ttcataacgt
    84601 caccctttgc tttactatta ctaaaagaat agcacataaa aaataaaaaa agaacacaaa
    84661 tcacatgtga gaagtgtgtt ctttttcatt cagctgcttt aattacaagt ttacgccatt
    84721 tgaggcaatt acttctttat accaatcaaa agattttttc tttgatcgat tcagtgtccc
    84781 atttccttca tcgtctagat ccacatagat aaagccgtaa cgtttactca tttctcctgt
    84841 tgatgcactg acaagatcga tacatcccca aggcgtatag cccatcaaat ctacaccgtc
    84901 tgctactgca ttagccatcg cttcgatatg acgacgtaaa taatcgatcc gataatcatc
    84961 aataatcgtg ccatcctctt ccatatgatc aatggctcca agaccgtttt caacaatgaa
    85021 taatggtttc tggtaacgat tgtataattc attcaatgcg attctcagcc cttctggatc
    85081 gatctgccag ccccattcac ttgcctcaag aaacggattt tttactcctc ccagcaagtt
    85141 cccttctgaa gttgctgctt gtggatcagt ctcattgatt gccgtagaca tataataact
    85201 aaatccgatg tagtccactg gatattcttt tagcaactgg aagtcttttt ccgtttgctc
    85261 taatttttcc ggatcgactc catatttttt atgggtacgc gctgtgtatg cagggtattc
    85321 tccacgtact tggacatccg tgcagaaaaa attgaattct tggttttgga tcattgttgc
    85381 tgcctgattg actggattgg catcgatgct gtaagttgtt gcatagataa tcatgcagcc
    85441 gatttggata tccgaacgca attcgtggcc gatttttacg gctttgctac ttgcaacgaa
    85501 ttgattatgc catgcttgga aaatattttg gtactctcct gctccattgc tttttactaa
    85561 tccttgactt aaagctggaa agtgaaaggc cgaattgatt tcattgaaag tcatccaata
    85621 tttgacttta ctgctgtatc tctctaatac tgtctgagca aatcgttcat agaagtcgat
    85681 cagttttcga tttttccagc caccgtattc ttttgccaaa tgaagaggca tttcgtaatg
    85741 agaaatcgtg atcacaggtt caatatcata ttttaagcac tcatcaatca gctgatcata
    85801 aaattctaat cccgcttcgt taggagtacc ttcgtctcca tttggaaaaa ttcgtgtcca
    85861 ggcaatcgaa aaacgataac atttgaatcc catttccgca aacaaggcaa gatcttcttt
    85921 gaaacgatcg taatgatcga ttcctcgatg attcgggtaa atatattttt cttgatcaat
    85981 cgtccagtca aattcttcac tgccgataat cgcaaagcgc tgcttacctc caggcatagc
    86041 atctgcaacg gatagtcctt ttccgtctcg atcataagcc ccttctaatt gatttggcag
    86101 cagttgctcc accccataaa aatttttctg aaaaacgtga ttgcatcctg atttcctcct
    86161 tattttacaa ttgccagaac atcttcgttt gcaataatct ctttttggtc taattcaagt
    86221 atatcggcaa atgcatcagt attcgtaatg acaactggag tgattacgct atagccagct
    86281 gctctaattg cttcgatgtc aaaacgaatc aataaatctc ctgctttgac gagatcccct
    86341 tgtttgacta agatctcaaa gccattccca tttaattcta ctgtatccat cccgatatga
    86401 atcaaaatct ccgctccgtc agtcgttgtg atccctacag catgtccagt tggaaaaata
    86461 gtcgtgatct ctccgtctgc aggtgcaact agttctccta cttctggatc aatagcgata
    86521 ccttttccca tcacgccaga agaaaaaact tggtctggta cttcactcaa tggcagtact
    86581 ttacccgtta aaggactttt taaggtatgc cgtgctgaag taatcggttc tcctgcattc
    86641 gcatgtttgt tttctaattg attgtcttgt gtttgttcgt caaatcctaa aatcaatgta
    86701 cctacgaatg caagaacaaa agcaattcct gtagctatta ctgctactgt cacatttgac
    86761 tctacaccat ccaccgtatt aatgaaagtc ggaatcgtca ataagctgac caaactgctg
    86821 gagaaagctt ttactccgga aaatccgata atagctccac caatacctcc agaaatacaa
    86881 gcggcaatga atggtttctt caaaggtaat gtcacaccat acacagttgg ttcagtgatt
    86941 ccaaataacg aagtcactgt agaagaaatc cctaatgctc gaagtttcgt atcttttgtt
    87001 cgcaatgcta cagctaaagc agccccacct tgtgccaaga tggctggaag aagcattggc
    87061 atcaatacat caaacccata ttgttcgata ttcaaaaaca tgatcggtac gaatccccaa
    87121 tgcatgccga acatcacgaa tacttgccat aaacttccca tgattagacc tgctacgatt
    87181 ggactaaatc cataaatcga gttgaagaga ccgcctaaag cattaccggc aaccgtcccg
    87241 attggtccta aagcaagaaa tgttaatgga accatcacta ctaaaacgac aagcggaact
    87301 aaaatcattt gcagaaattg cggaatcact ttttttacga atggctctaa tttactttga
    87361 acccatacgg ctagaatgat tggtatgaca gaagaagtat aaccagatgg tgaaagaatc
    87421 actgggatcc caaagaaact gatagcttct cccgcaccag caactgctgt gatagctgga
    87481 tacacaagtg ccatagcaat tgctactgct aaaaactggt tggctttgaa ctttttagct
    87541 gctgtaaaag caagcatgac aggtaagaag gtaaagacac catctgctgc agcaaacaat
    87601 atttgataag taccgctatc agctgtcagc cagcccatca ccgttgccaa tgataagaat
    87661 cctttcaata ccccggcggc tgccatcgcc cctagaaaag gtgtaaatat actagagata
    87721 atatcgatca gacgattcaa aatatttttg gactcttctt ttccatcctc cgaaactgca
    87781 agaccttcct catccacgat cgattgataa acatctgcta cattactgcc aatcactact
    87841 tgatactgac cgccactttg tacgacttgg atcacgtccg ggtcttcttt taacttttgc
    87901 gtatctgcta aagattcatc ttttaatctg aatcgcaacc gcgtagcaca atgtactaaa
    87961 cttttgacat tcttttgtcc tcctaccgct tcccatacac gacgaccaac tgcttgatta
    88021 tccattgttt tttccttctt tcttttttat ttaaaaaata aaaacccaga ttgaaaaaaa
    88081 cagtcacaaa cattcgtgaa cctatttttt caatccaggt tttgcctgcc atacagtaac
    88141 aatccttatg attggatgct ttttttctca cttactactc tttgaatatg aatcgttaaa
    88201 taaatctgct ctgcgatccc catttcctgt ttttgcgttt gtcgaagata ctcattgatc
    88261 cgttcgacac aatgaaacgc ttttggatac tttccttgaa ctaatgcgta gagaaattca
    88321 tcttgctcgt cagatccttc ccctttgaga taacgctggg caaaaaactg cagatgagta
    88381 atgatacgct gataattcaa agattcttca tcgaacacga tgccgaagaa tttactgatg
    88441 atactcagta tatctcttac cattgtggta gcggtcatcg tcacttgcat gtcttcgttt
    88501 ccttgttggc tattcacaaa atgaaaggca ataaaaccgg cttcatcctc agaaagttcc
    88561 acacccgtct tttgtttcac gaacaaaaga gcctctttcg ctgcttgata ttctttcgga
    88621 taaaattttt ttgtttcaaa taataatgga ttaggcagtt ggatattttc ttttgctcgt
    88681 gtgatcgcat aatgaagatg atcggtcaat gtcagataaa tattaggcga aaattcaact
    88741 tttagtttat cttcagccag ttcgactact tgtttgaccc attcgatctc ctctgccgga
    88801 atatcagcca tcagctgctg gaattggttt ttagcaaaag aatctcttaa aacaaattct
    88861 ttttggaccg cttctggcga aatctcgtcc ccaatctttt tttgaaaagc tagtcctttt
    88921 cccatacaaa cgacttcttc cccgaatcca tttttcgaaa tgacgacatt gttattcaaa
    88981 attttatcaa ttttcatttt gcttcgccct ctcaagaaaa ataaaaaaac ctagaattcg
    89041 cctactgttt cttagctgaa ttctggtttt gcctgccgta cagtaacaat ccatttctta
    89101 ttcaaaatca tcataccatc gaatttttat ttatgcaagc cttttcatat aaaaaataaa
    89161 aaaactggaa cacaagtcta tctagaaaac aa
//
LOCUS       DACDLM010000002        86119 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.002, whole genome shotgun sequence.
ACCESSION   DACDLM010000002 DACDLM010000000
VERSION     DACDLM010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 86119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 86119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..86119
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.002"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..741
                     /locus_tag="IV356_000082"
     CDS             <1..741
                     /locus_tag="IV356_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAP9013811.1"
                     /translation="SLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQW
                     ENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPT
                     IFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEG
                     NDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYHGSAKSNIGIDNLIEVITNKFY
                     SSTHRGPSELCGNVFKIEYTKKRQRLAY"
     gene            916..1212
                     /locus_tag="IV356_000083"
     CDS             916..1212
                     /locus_tag="IV356_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013812.1"
                     /translation="MQIGVLKWLQFTKQKGVHFPMQFLEPKNKNAKSVDWEISEQVRV
                     IVKQYAEYAERTESEAVDEFLLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            1219..3171
                     /locus_tag="IV356_000084"
     CDS             1219..3171
                     /locus_tag="IV356_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HAP9013813.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3243..3740)
                     /gene="dfrG"
                     /locus_tag="IV356_000085"
     CDS             complement(3243..3740)
                     /gene="dfrG"
                     /locus_tag="IV356_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HAP9013814.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            4102..5142
                     /locus_tag="IV356_000086"
     CDS             4102..5142
                     /locus_tag="IV356_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAP9013815.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQ
                     LKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSR
                     IDKVRYMFNKIT"
     gene            5240..5428
                     /locus_tag="IV356_000087"
     CDS             5240..5428
                     /locus_tag="IV356_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP9013816.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(5486..5839)
                     /locus_tag="IV356_000088"
     CDS             complement(5486..5839)
                     /locus_tag="IV356_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP9013817.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            6370..6792
                     /locus_tag="IV356_000089"
     CDS             6370..6792
                     /locus_tag="IV356_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAP9013818.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            6789..7019
                     /locus_tag="IV356_000090"
     CDS             6789..7019
                     /locus_tag="IV356_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP9013819.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            7517..7717
                     /locus_tag="IV356_000091"
     CDS             7517..7717
                     /locus_tag="IV356_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAP9013820.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            7744..8937
                     /locus_tag="IV356_000092"
     CDS             7744..8937
                     /locus_tag="IV356_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP9013821.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(9005..10570)
                     /gene="guaA"
                     /locus_tag="IV356_000093"
     CDS             complement(9005..10570)
                     /gene="guaA"
                     /locus_tag="IV356_000093"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAP9013822.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(10629..11552)
                     /locus_tag="IV356_000094"
     CDS             complement(10629..11552)
                     /locus_tag="IV356_000094"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HAP9013823.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            11748..12353
                     /locus_tag="IV356_000095"
     CDS             11748..12353
                     /locus_tag="IV356_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP9013824.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            12661..13677
                     /locus_tag="IV356_000096"
     CDS             12661..13677
                     /locus_tag="IV356_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP9013825.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            13818..15119
                     /locus_tag="IV356_000097"
     CDS             13818..15119
                     /locus_tag="IV356_000097"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HAP9013826.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            15165..15827
                     /gene="deoC"
                     /locus_tag="IV356_000098"
     CDS             15165..15827
                     /gene="deoC"
                     /locus_tag="IV356_000098"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HAP9013827.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            15848..16246
                     /locus_tag="IV356_000099"
     CDS             15848..16246
                     /locus_tag="IV356_000099"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HAP9013828.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            16312..17394
                     /locus_tag="IV356_000100"
     CDS             16312..17394
                     /locus_tag="IV356_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP9013829.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            17606..19168
                     /locus_tag="IV356_000101"
     CDS             17606..19168
                     /locus_tag="IV356_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9013830.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            19161..20294
                     /locus_tag="IV356_000102"
     CDS             19161..20294
                     /locus_tag="IV356_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9013831.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            20294..21250
                     /locus_tag="IV356_000103"
     CDS             20294..21250
                     /locus_tag="IV356_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9013832.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            21349..22515
                     /gene="deoB"
                     /locus_tag="IV356_000104"
     CDS             21349..22515
                     /gene="deoB"
                     /locus_tag="IV356_000104"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HAP9013833.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            22539..23357
                     /locus_tag="IV356_000105"
     CDS             22539..23357
                     /locus_tag="IV356_000105"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAP9013834.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            23374..24081
                     /gene="deoD"
                     /locus_tag="IV356_000106"
     CDS             23374..24081
                     /gene="deoD"
                     /locus_tag="IV356_000106"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAP9013835.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(24379..25065)
                     /gene="gpmA"
                     /locus_tag="IV356_000107"
     CDS             complement(24379..25065)
                     /gene="gpmA"
                     /locus_tag="IV356_000107"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAP9013836.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(25237..25818)
                     /locus_tag="IV356_000108"
     CDS             complement(25237..25818)
                     /locus_tag="IV356_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP9013837.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(25951..26634)
                     /gene="rpiA"
                     /locus_tag="IV356_000109"
     CDS             complement(25951..26634)
                     /gene="rpiA"
                     /locus_tag="IV356_000109"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HAP9013838.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            26953..27366
                     /gene="rpsL"
                     /locus_tag="IV356_000110"
     CDS             26953..27366
                     /gene="rpsL"
                     /locus_tag="IV356_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007085295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HAP9013839.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            27450..27920
                     /gene="rpsG"
                     /locus_tag="IV356_000111"
     CDS             27450..27920
                     /gene="rpsG"
                     /locus_tag="IV356_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HAP9013840.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            28014..30101
                     /gene="fusA"
                     /locus_tag="IV356_000112"
     CDS             28014..30101
                     /gene="fusA"
                     /locus_tag="IV356_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAP9013841.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            30273..31460
                     /gene="tuf"
                     /locus_tag="IV356_000113"
     CDS             30273..31460
                     /gene="tuf"
                     /locus_tag="IV356_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAP9013842.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            31867..32175
                     /gene="rpsJ"
                     /locus_tag="IV356_000114"
     CDS             31867..32175
                     /gene="rpsJ"
                     /locus_tag="IV356_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HAP9013843.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            32206..32835
                     /gene="rplC"
                     /locus_tag="IV356_000115"
     CDS             32206..32835
                     /gene="rplC"
                     /locus_tag="IV356_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HAP9013844.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            32863..33486
                     /gene="rplD"
                     /locus_tag="IV356_000116"
     CDS             32863..33486
                     /gene="rplD"
                     /locus_tag="IV356_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HAP9013845.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            33486..33776
                     /gene="rplW"
                     /locus_tag="IV356_000117"
     CDS             33486..33776
                     /gene="rplW"
                     /locus_tag="IV356_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HAP9013846.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            33815..34648
                     /gene="rplB"
                     /locus_tag="IV356_000118"
     CDS             33815..34648
                     /gene="rplB"
                     /locus_tag="IV356_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010747214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HAP9013847.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            34691..34969
                     /gene="rpsS"
                     /locus_tag="IV356_000119"
     CDS             34691..34969
                     /gene="rpsS"
                     /locus_tag="IV356_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HAP9013848.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            34992..35339
                     /gene="rplV"
                     /locus_tag="IV356_000120"
     CDS             34992..35339
                     /gene="rplV"
                     /locus_tag="IV356_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HAP9013849.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            35353..36009
                     /gene="rpsC"
                     /locus_tag="IV356_000121"
     CDS             35353..36009
                     /gene="rpsC"
                     /locus_tag="IV356_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HAP9013850.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            36012..36446
                     /gene="rplP"
                     /locus_tag="IV356_000122"
     CDS             36012..36446
                     /gene="rplP"
                     /locus_tag="IV356_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HAP9013851.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            36436..36624
                     /gene="rpmC"
                     /locus_tag="IV356_000123"
     CDS             36436..36624
                     /gene="rpmC"
                     /locus_tag="IV356_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HAP9013852.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            36649..36915
                     /gene="rpsQ"
                     /locus_tag="IV356_000124"
     CDS             36649..36915
                     /gene="rpsQ"
                     /locus_tag="IV356_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HAP9013853.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            36973..37341
                     /gene="rplN"
                     /locus_tag="IV356_000125"
     CDS             36973..37341
                     /gene="rplN"
                     /locus_tag="IV356_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002460061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HAP9013854.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            37378..37686
                     /gene="rplX"
                     /locus_tag="IV356_000126"
     CDS             37378..37686
                     /gene="rplX"
                     /locus_tag="IV356_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HAP9013855.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            37714..38253
                     /gene="rplE"
                     /locus_tag="IV356_000127"
     CDS             37714..38253
                     /gene="rplE"
                     /locus_tag="IV356_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HAP9013856.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            38272..38457
                     /locus_tag="IV356_000128"
     CDS             38272..38457
                     /locus_tag="IV356_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HAP9013857.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            38493..38891
                     /gene="rpsH"
                     /locus_tag="IV356_000129"
     CDS             38493..38891
                     /gene="rpsH"
                     /locus_tag="IV356_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HAP9013858.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            38923..39459
                     /gene="rplF"
                     /locus_tag="IV356_000130"
     CDS             38923..39459
                     /gene="rplF"
                     /locus_tag="IV356_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HAP9013859.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            39620..39976
                     /gene="rplR"
                     /locus_tag="IV356_000131"
     CDS             39620..39976
                     /gene="rplR"
                     /locus_tag="IV356_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HAP9013860.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            39997..40497
                     /gene="rpsE"
                     /locus_tag="IV356_000132"
     CDS             39997..40497
                     /gene="rpsE"
                     /locus_tag="IV356_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HAP9013861.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            40512..40691
                     /gene="rpmD"
                     /locus_tag="IV356_000133"
     CDS             40512..40691
                     /gene="rpmD"
                     /locus_tag="IV356_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HAP9013862.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            40735..41175
                     /gene="rplO"
                     /locus_tag="IV356_000134"
     CDS             40735..41175
                     /gene="rplO"
                     /locus_tag="IV356_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HAP9013863.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            41175..42470
                     /gene="secY"
                     /locus_tag="IV356_000135"
     CDS             41175..42470
                     /gene="secY"
                     /locus_tag="IV356_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HAP9013864.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            42532..43179
                     /locus_tag="IV356_000136"
     CDS             42532..43179
                     /locus_tag="IV356_000136"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HAP9013865.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            43370..43588
                     /gene="infA"
                     /locus_tag="IV356_000137"
     CDS             43370..43588
                     /gene="infA"
                     /locus_tag="IV356_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HAP9013866.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            43621..43737
                     /gene="rpmJ"
                     /locus_tag="IV356_000138"
     CDS             43621..43737
                     /gene="rpmJ"
                     /locus_tag="IV356_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HAP9013867.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            43755..44120
                     /gene="rpsM"
                     /locus_tag="IV356_000139"
     CDS             43755..44120
                     /gene="rpsM"
                     /locus_tag="IV356_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HAP9013868.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            44148..44537
                     /gene="rpsK"
                     /locus_tag="IV356_000140"
     CDS             44148..44537
                     /gene="rpsK"
                     /locus_tag="IV356_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HAP9013869.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            44617..45555
                     /locus_tag="IV356_000141"
     CDS             44617..45555
                     /locus_tag="IV356_000141"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HAP9013870.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            45583..45963
                     /gene="rplQ"
                     /locus_tag="IV356_000142"
     CDS             45583..45963
                     /gene="rplQ"
                     /locus_tag="IV356_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HAP9013871.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            46235..47074
                     /locus_tag="IV356_000143"
     CDS             46235..47074
                     /locus_tag="IV356_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAP9013872.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMIFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            47050..47919
                     /locus_tag="IV356_000144"
     CDS             47050..47919
                     /locus_tag="IV356_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAP9013873.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            47909..48706
                     /locus_tag="IV356_000145"
     CDS             47909..48706
                     /locus_tag="IV356_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAP9013874.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            48909..49655
                     /gene="truA"
                     /locus_tag="IV356_000146"
     CDS             48909..49655
                     /gene="truA"
                     /locus_tag="IV356_000146"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAP9013875.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(49988..52657)
                     /locus_tag="IV356_000147"
     CDS             complement(49988..52657)
                     /locus_tag="IV356_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAP9013876.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDGGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(52895..53083)
                     /locus_tag="IV356_000148"
     CDS             complement(52895..53083)
                     /locus_tag="IV356_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HAP9013877.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            53353..53715
                     /locus_tag="IV356_000149"
     CDS             53353..53715
                     /locus_tag="IV356_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAP9013878.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            53767..55449
                     /locus_tag="IV356_000150"
     CDS             53767..55449
                     /locus_tag="IV356_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HAP9013879.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            55566..57602
                     /gene="recG"
                     /locus_tag="IV356_000151"
     CDS             55566..57602
                     /gene="recG"
                     /locus_tag="IV356_000151"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HAP9013880.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            57651..58652
                     /gene="plsX"
                     /locus_tag="IV356_000152"
     CDS             57651..58652
                     /gene="plsX"
                     /locus_tag="IV356_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HAP9013881.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            58774..59016
                     /gene="acpP"
                     /locus_tag="IV356_000153"
     CDS             58774..59016
                     /gene="acpP"
                     /locus_tag="IV356_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAP9013882.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            59284..60288
                     /locus_tag="IV356_000154"
     CDS             59284..60288
                     /locus_tag="IV356_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9013883.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            60289..61233
                     /locus_tag="IV356_000155"
     CDS             60289..61233
                     /locus_tag="IV356_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9013884.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            61233..62195
                     /locus_tag="IV356_000156"
     CDS             61233..62195
                     /locus_tag="IV356_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9013885.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            62222..63136
                     /locus_tag="IV356_000157"
     CDS             62222..63136
                     /locus_tag="IV356_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9013886.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            63162..64943
                     /locus_tag="IV356_000158"
     CDS             63162..64943
                     /locus_tag="IV356_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP9013887.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            65291..65977
                     /locus_tag="IV356_000159"
     CDS             65291..65977
                     /locus_tag="IV356_000159"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAP9013888.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            65997..69578
                     /gene="smc"
                     /locus_tag="IV356_000160"
     CDS             65997..69578
                     /gene="smc"
                     /locus_tag="IV356_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HAP9013889.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            69587..70396
                     /locus_tag="IV356_000161"
     CDS             69587..70396
                     /locus_tag="IV356_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP9013890.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            70407..71405
                     /gene="ftsY"
                     /locus_tag="IV356_000162"
     CDS             70407..71405
                     /gene="ftsY"
                     /locus_tag="IV356_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HAP9013891.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            71592..73859
                     /gene="gshAB"
                     /locus_tag="IV356_000163"
     CDS             71592..73859
                     /gene="gshAB"
                     /locus_tag="IV356_000163"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HAP9013892.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(73948..74400)
                     /locus_tag="IV356_000164"
     CDS             complement(73948..74400)
                     /locus_tag="IV356_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HAP9013893.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            74550..75500
                     /locus_tag="IV356_000165"
     CDS             74550..75500
                     /locus_tag="IV356_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAP9013894.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            75493..76452
                     /locus_tag="IV356_000166"
     CDS             75493..76452
                     /locus_tag="IV356_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAP9013895.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            76449..77204
                     /locus_tag="IV356_000167"
     CDS             76449..77204
                     /locus_tag="IV356_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP9013896.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            77227..78180
                     /locus_tag="IV356_000168"
     CDS             77227..78180
                     /locus_tag="IV356_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP9013897.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(78824..79120)
                     /locus_tag="IV356_000169"
     CDS             complement(78824..79120)
                     /locus_tag="IV356_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HAP9013898.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            79475..79831
                     /locus_tag="IV356_000170"
     CDS             79475..79831
                     /locus_tag="IV356_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAP9013899.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            79841..80740
                     /locus_tag="IV356_000171"
     CDS             79841..80740
                     /locus_tag="IV356_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HAP9013900.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            81257..81988
                     /locus_tag="IV356_000172"
     CDS             81257..81988
                     /locus_tag="IV356_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAP9013901.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            82133..84160
                     /locus_tag="IV356_000173"
     CDS             82133..84160
                     /locus_tag="IV356_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lectin"
                     /protein_id="HAP9013902.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGHSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            84268..85365
                     /locus_tag="IV356_000174"
     CDS             84268..85365
                     /locus_tag="IV356_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAP9013903.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            85672..>86119
                     /locus_tag="IV356_000175"
     CDS             85672..>86119
                     /locus_tag="IV356_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAP9013904.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRKL"
BASE COUNT        28345 a        15353 c        18251 g        24170 t
ORIGIN      
        1 agcttattat ataacagtgg agcgattaca gaattaggaa gcgtggacaa aggtacaacg
       61 aggacggata atacgctttt agaacgtcag agaggaatta caattcagac aggaataacc
      121 tcttttcagt gggaaaatac gaaggtgaac atcatagaca cgccaggaca tatggatttc
      181 ttagcagaag tatatcgttc attatcagtt ttagatgggg caattctact gatttctgca
      241 aaagatggcg tacaagcaca aactcgtata ttatttcatg cacttaggaa aatggggatt
      301 cccacaatct tttttatcaa taagattgac caaaatggaa ttgatttatc aacggtttat
      361 caggatatta aagagaaact ttctgccgaa attgtaatca aacagaaggt agaactgtat
      421 cctaatatgt gtgtgacgaa ctttaccgaa tctgaacaat gggatacggt aatagaggga
      481 aacgatgacc ttttagagaa atatatgtcc ggtaaatcat tagaagcatt ggaactcgaa
      541 caagaggaaa gcataagatt tcagaattgt tctctgttcc ctctttatca tggaagtgca
      601 aaaagtaata tagggattga taaccttata gaagttatta ctaataaatt ttattcatca
      661 acacatcgag gtccgtctga actttgcgga aatgttttca aaattgaata tacaaaaaaa
      721 agacaacgtc ttgcatatta agtagttcag ttttggagta caaaaagtga aaatgtaaac
      781 ctaaatgagt atcaaattgc aactgaattt gatactcgtt ttttattgtt aaatcaacgt
      841 ttgttgttaa tttacaccac aaaatgtaag ttaaaatgta tataaaaatg cgaacgtgaa
      901 ataattattg taggaatgca aattggtgtg ttaaaatggt tacaatttac taagcaaaaa
      961 ggggtgcatt ttcctatgca atttcttgag ccaaaaaata agaacgctaa gtctgtggat
     1021 tgggaaatat cagagcaagt aagggtgata gttaagcaat acgctgaata tgcagagcgt
     1081 actgaaagcg aagcagtgga tgaattctta ttgaacattt tagacgataa gaagtttatt
     1141 gaatggattg ccaacaagcg aagtaataag cggattgttg aaaaaatggg tatcaaagat
     1201 agagtgggtt gatagacaat gaccaagctt aaaagattag ccacgaagga agatgaaatt
     1261 gtagatgtta aaattccgat ttcaaacgaa gaattaaaag atagggctaa acaatatgat
     1321 ttattaactc caaaacgatt tgcaacaagg tataacaaaa tgttgttctt gccaacgtct
     1381 tttaaatgga acggttctga atatcccatt caatataatt actgcatcaa tccgttttgt
     1441 tgtaattttg ggaaagaaca gcacaaattc aaagatgtaa aagggaaacc aagtcgatat
     1501 aaaatgactg gtagttccaa agataaaggt cataaaggta tgtactgcaa tgacaatcct
     1561 attggcagag gtgtatcgca aaactgtaca gtaacccctt tatctaattg gtctgttgtt
     1621 gaagaaatta aacgccttat agaaatcaat agcatccaag atgttgagcc agattatcaa
     1681 tttcataaag aaggctgctc ggaagaagaa tcaaccccat tcaatgagcc gaagcaattt
     1741 tacaaaaggg ggaaaagtag gggcaaatct caacgctatc aatgtaaggc gtgtaagaag
     1801 ttcactaatg ttctaccaaa aagagaagaa accactactt atcaccaaca aaagaacacc
     1861 attcttccaa tgttcgctaa gatggttgtt ggaagggttt cagtcagtcg tacttgtgat
     1921 attttaggaa ttggagttgg aacctactat cataagctgg agtggctgta taggcgttgt
     1981 ttggagtttt tagaacgata tgagacacaa ccccttcaaa caaagaaatt taacgagatg
     2041 tggcttaata cggacaagat gcactactac ctaaataacg tccgtaagaa aggacaaggt
     2101 tcaaagaaat atacggggtt tgaagacctt aatatgcaaa cgtatatagt tgtatctgct
     2161 gaggtcttat caagatatgt gttccgttct gatgttgcct atgattggaa tatttcaatg
     2221 gatgaattaa atgaagatac aagaaaattc aaagaagacc atctcaatac ttttagtcgt
     2281 aaaaatgata ggttagattg gtcttattat ccacaagaac catccgctaa cgatagcgaa
     2341 aataggaatg cttatcttca cgaattaggg aaaattacta ataggagtag atttgtcgat
     2401 ggtttaaatg ttgatgctcc ttatactaca actgctcact attggttaat taaacaaatg
     2461 gttaatgccg acgaatggcg aatgattagt gatgatgact tctctattag aaacgccttt
     2521 tatagagtat tcacgaaaga attaaggttg agcgatgcac atcattttat ttgccaagtt
     2581 aacaagacga aaagcagaaa acaatgctta aaagaattcg gacaagcaaa agcagaactg
     2641 ctcgattggg gagatatcag aggattcaaa acaaagtttc tacggacttt ggcatctcat
     2701 tatctaactg aattactaac aagtcatcaa ttccacgaag aggctattag taaagatgga
     2761 gaaagatatc gcaaatatgc cgataaccct atcaaacatc cattagccac taaggataaa
     2821 ggattttatt cagttgattg tagaacggat ttatctgctc tggaaccaaa cgaaatcgca
     2881 aagatgctat taaatgttaa tgaccattcg accaatagct ttattcaaca gataagacgt
     2941 tatatatcat ctcttgaaag accattaaca acagctcgtg gtgataagaa gagctatatt
     3001 tacgctaact tcaatccgaa gtatgctcaa tttgcgatta caattctaag aacttactac
     3061 aacttttgtc gcccttttaa atcagcggat aaaaaggttt tgacacctgc tcaaagatta
     3121 gggattacag ataaacaatt tgattggaaa gatataattt atttcaaatg acaaaaagag
     3181 cttggagtaa tcccaagctc ttgtgcttta tctttactgt tcttcttcaa ttaacgcacc
     3241 cgttaactca ataagttttt tctttcatat acatgaaaat agtagttata cggattttta
     3301 tcattcttta tccctttttg ggcaaatacc tcattccatt cctcataatt cacttctgga
     3361 aaaaaagtat ctccttcgaa ttcatgatgt atttttgtga tgtacatttt ctcaacataa
     3421 gggaaaaaca aattataaat ctgttctcct ccgaaaataa aaatttcttc ttcgttttta
     3481 cataactcaa aaacatcttc tattgaatga acaatttcac aaccattaaa ggtaaacccc
     3541 ttatctctcg tcagaataat atttcttctg tcaggtaagg ctcttccgat tgattcaagg
     3601 ttcttcctac ctaatattat cggatgtccc tttgtagtat ttttaacata ttcccagtcc
     3661 ttgggaatcc tccaaggaat gtcattctct ttgccaatca ctctattctt atccatcgca
     3721 gcaatcaaag aaactttcat ttataacaca gcctttttaa ctaatttacc atctaatttc
     3781 ttatttctat caaaaaacct tttctcatta tcctgcccgt tagttgaata agcaattttt
     3841 tctataagtt atattatcat aataccacaa aatcacaaat tttcattcaa ttatcatttt
     3901 caattgcatt ttataaatca ttttgtatgt aatttggtat gtaagttaaa atgaaaaaag
     3961 tagtccattt tgaagtacat tttgtcattt tgtactccaa aactgaacta cttacttgca
     4021 tatatacgcc tttatagtgg agtactacat ttacgagatt cggttagagt atcagaaaaa
     4081 gaaaaaataa aagttacaga aatgtatact tcaataaatg gtgaattatg taagattgat
     4141 agagcttatt ctggagaaat tgttattttg caaaatgagt ttttgaagtt aaatagtgtt
     4201 cttggagata caaaactatt gccacagaga aaaaagattg aaaatccgca ccctctacta
     4261 caaacaactg ttgaaccgag taaacctgaa cagagagaaa tgttgcttga tgcccttttg
     4321 gaaatctcag atagtgatcc gcttctacga tattacgtgg attctacgac acatgaaatt
     4381 atactttctt tcttagggaa agtacaaatg gaagtgatta gtgcactgtt gcaagaaaag
     4441 tatcatgtgg agatagaact aaaagagcct acagtcattt atatggagag accgttaaaa
     4501 aatgcagaat ataccattca catcgaagtg ccgccaaatc ctttctgggc ttccattggt
     4561 ttatctgtat caccgcttcc gttgggaagt ggaatgcagt atgagagctc ggtttctctt
     4621 ggatacttaa atcaatcatt tcaaaatgca gttatggaag ggatacgcta tggttgcgaa
     4681 caaggattat atggttggaa tgtgacggat tgtaaaatct gttttaagta cggtttatac
     4741 tatagccctg ttagtactcc agcagatttt cggatgctta ctcctattgt actggagcaa
     4801 gcctttagaa aagctggaac agaattgtta gagccatatc ttagttttaa agtttatgca
     4861 ccacaggaat atctttcacg ggcatataac gatgctccca aatattgtgc aaatatcgta
     4921 aatactcaac tgaaaaataa tgaggtcatt attattggag aaattcctgc tcgatgtatt
     4981 caagattatc gcaatgattt aacttttttt acaaatgggc ttagtgtttg tttagcagag
     5041 ctaaaaggat atcaggttac cactggcgaa cctgtttgcc agacccgtcg tctaaatagt
     5101 cggatagata aagtaagata tatgttcaat aaaataactt agtgcgtttt atgttgttat
     5161 ataaatatgg tttcttatta aataagatga aatattcttt aatatagatt tgaattaaag
     5221 tggaaaggag gagattgtta ttataaacta caagtggata ttgtgtccta tttgtggaaa
     5281 taaaacaaga ctacgaatac gagtggatac tatacttaaa aatttccctt tatactgccc
     5341 caaatgtaag aacgaaactt taattaatgt tcaaaaaatg aatataataa caatcaaaga
     5401 gccagacgcc aagacgcaga gccgataatt tgagaaatga aactctcatc ttatcggctc
     5461 tttttgttta tctgaatttt actgactagc cttcaatatt tcttgcttca ttgatacctt
     5521 ttgctagtgc ttccattaag gatagttctt tgtctgtaaa gctatccatg tatttttcta
     5581 cctgtaacct tcgagtgctt ttaatcaaat tatctgtagg taagaaaaat tcatcaatag
     5641 atacatggag taatgataca agatcataca gcacttgtgt acttgggtgt tgtcctttgt
     5701 tttctatatt tgttaaataa cgtgggtcaa tttcaatcat tgttcccact tgttcacgag
     5761 tgagaccccg tttcattcga gcctctttaa tcgctaaacc aacggctcta aaatcgtatt
     5821 tatcttcttt tttacgcata ctaaatcacc tctatacatt ttactgttcc tatataacca
     5881 taaacaggta tagaaaaaca tgttatatag tttatgagtt cctatagaac actgtggaat
     5941 ttattaatgc gatgaatcca atttcaaata gaaaggtcgc tgattttatt tacctataca
     6001 actttataaa atttagtcat actcctagaa agtagataaa attggcgact taatggaggg
     6061 aaaagtcgcc atgagaaaga taatctgtca tctagttctc ttaattaagt tcttatcaaa
     6121 aaaacttatc cacctgtact ggatagatat gaccatcaat gtggttttgc agattacata
     6181 gatagaaaaa tcaaagcata tgaacagaga aaacaatctg tttatgtgct tttttggtca
     6241 cttaataaat atcttttagg atttctcttc atttatgcaa caaatccccc gttcgtgtcg
     6301 gggtttagta tgaagggaga taaagaagca catgccactc cctttcacga cagaaagggg
     6361 gtgaaaagca tgaaaccatc ttcttttcaa gaaaccatag aaaatcagtt tgactatatc
     6421 tgcaaacaag ttattgaaga tgaacgaaaa gattacttca aacatctaga cagactatca
     6481 gcaaaagaag tctcgttttc tgatatagat aactaccttg tcaactcttt ttctactgtt
     6541 gatacgtacg tcactgattt ccaactattt aaattatttg gattaagaat caatgttgaa
     6601 agtgatttat taagtgaagc cctgcgtcat ctttcagaga aaaaacggaa cattatttta
     6661 cttcattact ttatggatat gagtgatgtg gagattgcgg agttactaaa tttgaatcgt
     6721 tcgactgttt atcgtcatcg aataagtgga ctagccatga ttaaagaatt catgaaggag
     6781 tgtaaagaat gaaaacagct tatccaaggg ttcccttccc cctcattgta aaggcgacag
     6841 atggcgacgt ggaagcaatt aatcagattg ttaaacatta tcgagggtat acctcaaaac
     6901 gttcattacg tcgcatgaca gacgaatatg gaaattctca tatggttatt gatgaaaccc
     6961 tacgtggcag aatggaaacg aaactcatct ctaagatttt atcgttcgaa attaaatagt
     7021 cccatttttt cgtggaagcg tgtcgaatcg tatccacgct tcccgatttg ggaggtttgt
     7081 tattccatca aagcatattg tgtgttcagt aggttttgat aggctaacaa gccaaacgtt
     7141 ctttgacaac caaataaagg caatcgaata cgtttcggta agaaaagagc tgatgaacta
     7201 acacgccatg acctacaaaa ttagtgagcg attcatgtta gtaattcgaa agtaatcttt
     7261 agcaggattg ctgccatgac tttcttatcg tgataatgat actcccgtat agccatagtc
     7321 cgagcgttag aagcgtcaca ggcaatgggt acggctacat gagaaccatg cagaagtgaa
     7381 attcctgtga gctttgctag agctgttcga ttgctaagat attcttctct tgtcagtgta
     7441 ttattataaa actatttgat ataattatag gtgaatattg gagttttcct agcctataat
     7501 tgggaaagga gtaataatga taacggtcac aaaaaaggat ttagttgagc taggatatgg
     7561 aacttctttt tcagcagaca tcataaaaaa agcaaaagaa ttgatgatta caaaagggca
     7621 tatctactat caatctcgaa agctagatag agtccctcgt gaagctgttg aagaaattct
     7681 aggaattcgg ttttcaaatg aaaacaggtc tgagtagttt ttgcacagta aggagtaaaa
     7741 actatggtta aagacccaat aaaaaaagca aagaatggaa cctattattt tcgtgcaaat
     7801 ctaggttatg attctaaagg gaaaaaaatt caaaaatatc gtagtggatt cactactaaa
     7861 aaagaagcaa gagaagaata ttcgaaactg ctattgatga aaccagaaga attaagtgag
     7921 aataaggata aaatgacgtt taaacattat atctttgaaa ttttccttcc atggtataag
     7981 acacaggtaa agctcagaac atatgaaaat cgcttaccaa ctattaagaa gcatttctct
     8041 tattttgata aaatggctgt ttccgatatt gagcctattg atgtgcaaaa ttggcaacta
     8101 aaattatcaa agaagtgtaa gtcttcttat gtaagagctg ttcaaggact attttcagtt
     8161 gctatggatc gagcaattgt ccttgggata accaccacaa atccatctaa gattattggc
     8221 aatgtgaaaa agcaaaagtc taaaattgaa ttttggacaa aagaagaatt tgaaaaagta
     8281 atctctctaa tttacaaaga agattactat caacactttt tatttatctc tctgtggttt
     8341 ttatttatga ctggaatgcg aattggtgaa gctactgcca ttcaatggga agatattgat
     8401 tttgactcag gagtactaac catcaacaaa acactctatt acaagaatca atcgaattat
     8461 agatttgttg aaccaaaaac aaaggcgagc gttcgtcata ttgtattaga taaatgcaca
     8521 ttaacttatt tatccgaatg gaaggaagta caacaaaatc taattcagac agactttgta
     8581 atgagctata acggtattcc tacccaaaaa catacactat catatgctat tgaacgctat
     8641 gctaagctgg ctggtatcca tcgaatcaga atccatgggt tacggcattc tcatgcttcc
     8701 ttgttaatca gtatgggaga aaatccactt atcattaaag atcgtctagg acacgaagat
     8761 attgagacga ctttaggaac gtatggacat ctttatccta acagtaattt cgaggtagct
     8821 aacaaattaa atggagccat ttcctttaaa gaagcaaaac aaaattatga tacttcacca
     8881 aagaatcaat ttactgtaga ctacttgcga aacaaagaaa tgaaaaaagt gcaataaaag
     8941 tgcagtaaaa agataagaag agccagaaac ccttggtata agaggatttc tagctctcct
     9001 acaactattc ccactccact gttgctggtg gtttagaagt gatgtcatac acgatacggt
     9061 tgacgtgggc tacttcgttt acgatacgta cagagatttt ttgcaagact tcccatggga
     9121 tacgggcaaa gtcagcggtc attccgtcga ttgaagttac agcacggata ccgactgtgt
     9181 agtcgtaagt acgtccgtca cccataacac cgacagagcg gatccctgga agaacagtga
     9241 aatattgcca gatatcacgg tcaagtccag cagctgcgat ttcttcacgc aagatagcat
     9301 cagattcgcg tacgatttct agcttgtctt cagtgatttc gccaagaaca cgaataccaa
     9361 gaccaggacc agggaatggc tgacgccaaa cgattgaatc aggcatgcct aactgagtcc
     9421 ctaattcacg gacttcgtct ttgaataatg tgtttaatgg ttcgatcaat tcaaattgca
     9481 tatcttctgg cagtccacct acattatggt gagatttgat cgtctgtgct gtttctgtac
     9541 cagattcgat aacgtcagta tacaacgttc cttgtgctag gaaagagacg ccttcttcac
     9601 cagcaagttt tgttgcttcg tcatcaaaaa catatacgaa ttcattccca atgattttac
     9661 gtttttgttc tgggtcagat acacctttca acttgtctaa gaagcgatct cttgcatcga
     9721 ctttgatgat gttcaagccg aattttccgc ctagactttc cattacttgt tccgcttcgc
     9781 ctttgcgtag cagaccgtgg tcaacaaaga tagatgtcaa ttggtcaccg atcgcttttt
     9841 gtaaaagaac cccaacgaca ctagaatcaa cgccacctga aagaccaagc aagacttttt
     9901 tgtcaccaac ttgttcacgg attttttcta cttgcatatc gataaagtta tccattgtcc
     9961 agttaccttc acagtgacaa acatcaaagg caaagtggcg cagcaattcg attccgtatt
    10021 cggaatgacg tacttctgca tggaattgga taccataaaa attacgtgtt gtgtcttgga
    10081 tagaagcaat cggacaatct ttgcttgttc cgactgtttc aaagccttca ggaactttag
    10141 ttaccaagtc accatggctc atccatactg tttgttgttt tggtgtttct ttaaacaaga
    10201 cagcttgatc gcttgttact tctaacaagg ctttcccata ttcgcggttt ttagcaggct
    10261 ctacggaacc gccaagtttg tacgtgatca attgcatacc atagcaaatc cctaatacag
    10321 gaatacctaa attgaagatc tcaggatcga tcccaaatgc attctcatca tatacactgt
    10381 ttggtccgcc agaaagaatg attccctttg gattcatcgc ttttacttct tctgcagtaa
    10441 tgcggtggct caataattcg gaaaagactc caagatcacg aatacgtctt gtgatcaatt
    10501 ggttatactg actaccgtag tctaatacga taatcttttc aacgttcgtc atatcggcaa
    10561 cgtttgtcaa atttattacc cctatccctt taaattttat ctcaaaatag tcaaactatt
    10621 ttaaaatgct aatattttcg catgaaaatc gaatcgatga tatgattttc agttttatgg
    10681 agaattatat cggctcttcc tcgtgtaggc aagatatatt cctgtaaatt tttcaaattc
    10741 acatttttcc atacatcttt tgccatttta aaggcttctt cacgatctcc gatagcaaaa
    10801 cgataataat aattctctgg attttggaaa gccgtatcca gtaacgcacc aaaacgatcc
    10861 aaataccatt tttcgatcag cacgggatcg gcatcgacat agacagaaaa atcaaaaaag
    10921 tcgctgacgt agatttgctg attcgcaggt aattgaagcg tattgatccc ctcaacgatc
    10981 aagatatcag gctgctggat caattcgtac ttgtctggaa tgatatcata cacatcatgt
    11041 gagtaaacag gtacttttat ctcttcctga ccagatttta cacggttcaa gaaatcgatc
    11101 agcatctcca tatcataact ttcaggaaat cctttacggt ccatgattcc acgctctttt
    11161 aatatacgat ttggataaag aaatccgtca gtcgtgatca gctgaacgtt tcttcgtttg
    11221 aaggtacgag acaaaatcgt ctgcagcagt ctggctgttg tactttttcc aacggctaca
    11281 cttccggcga tcccgataat aaaaggcggt acttctacgt atttatgaag aaataaacct
    11341 ttactcaaga acaaagattc aaattctttc atataaagat aaatcagatg agcaagaggt
    11401 acatagatat ctcgaacatc ctgcatggaa atgcggtcat tcaaactttt gatattatct
    11461 agttcatctt gtgtcaaagg tgcttgccca ttacgataaa attctcgcca ttcttctctt
    11521 gccacacggt agtagttcat tggatcattc atattagcct cctgcgttct cccatcaatg
    11581 gaactatttt aacacaaaat aaacgcaaac cccaccactt aagagagatt gccgatcttt
    11641 ttgtataatc tttataatag aaagaaacgg agtcttattc ttgacttgcg cacggataca
    11701 taaaaggata gactgttgtc atgaaagaaa tgagaaggat ggaagacatg acaaatcatt
    11761 actattctga acgcccagat acggcgcacg attttgaaca atgggctttt gagttaaaag
    11821 gcagaacctt tcaatttgta acagattctg gtgtattttc acgtgaaaca gtggattatg
    11881 gttcacgtgt cctgattgat gctttcgatt gggaagagtt acctgatgaa ggaaagatct
    11941 tagatgtggg atgcgggtat ggaccgattg ggttagcttt ggcatttgcg acacagcggt
    12001 ttgttgaaat ggtcgacatt aatgaacgag cggtaagtct agcgcaagga aacgcaaagc
    12061 gtaaccaaat cgaacatgtt gatatccatc aatcgaatat ctatgaagca gttcatgaag
    12121 aaacctatgc agctatcgta agcaatccgc cgatccgtgc tggaaaaaaa gttgtacatg
    12181 aaattttgac aggcgcatat cctcggttga agaagggcgg tacactgaca attgtgatcc
    12241 agaagaaaca aggagcgccg agtgcgcaaa agaaaatgga agaaacattt ggtaatgcag
    12301 aaatcgtcac aaaagataaa ggatattata tcatcaaaag tgtgaaagaa taactagctg
    12361 aaaaatagtg gagcgacgaa agagtggaac tgggcgtgca tgtacgggta cgtatcagtt
    12421 ctttttttgt tgagaagttt ttaaaaacaa agaactattt tttcttcaaa aagaaatagt
    12481 aggaacagag tcgttgtttt ttacgataaa ataaataaga tacagaactt gtatagaagg
    12541 ctgccaagtc ggtagataaa ggaggttttt atcaaaaaac atactttcct tttttctcta
    12601 ttcttttctt gggggttttg gtacactgat agggaattta gatagaaggg agccaatagg
    12661 atgaagctga ccatcagaga tatcgcagaa atggcaggcg tatcagtaac aactgtctca
    12721 cagattttga ataacaaagg aagcagattt agtgataaga caagaaaaaa agtgttgtcg
    12781 atcgtgaatg aacatcatta taagcccgat tatttcgctt caaatgtgat caatcgacat
    12841 tcaaagacca tcggaatgat cgtccctgat gtcactgatt tcttcttctc caaactgatc
    12901 gaaggtgtag agagctattt gaatcctttg ggctatgtga tcatgttatg caattctcgt
    12961 catagccaag aaaatgagat caagtattta caagagcttt cccaccgctc agtggacgga
    13021 atcttgctgg ccacaccaaa tattttacct gagaaatatg cattagacag cggtttttat
    13081 caaaaaatgc caatcatttt aatcgatcgc ggattgaatc gtcgggataa cggacggctt
    13141 atcgtaaagg aatatgaggg cgcctatcaa gctgtttcgc tgtttattga aaatggccat
    13201 acgaagatcg gcatgctgaa ggaaaccact ggatactatc aattagaaga acgtttcaac
    13261 ggatatcgtc atgcgctgaa agatcatggc ctgcctttta atgggaaatt tgttgaacat
    13321 ggagagttga ctgtccaagg tggatatact gcatcaaaaa aattactcaa acataaagat
    13381 atcacggcta ttttttgcgg gaatgatgcc atggcgatcg gatgctatca ggcgatcgat
    13441 gaattgggca aaaaaatccc agaagatatc tcagtcatag gattcgatgg attaaagctg
    13501 tcagaataca tgattccgca attgacgaca gtgcagcagc caagttttga tattggattt
    13561 tatgctgcac gtttcctgat cgatacgatc gaatttcctc aaagaaaagt tccgaacaaa
    13621 gtgttcgaaa caaaattaat tattcgtgag agcgtaaaag tattgacaaa gggctaactc
    13681 ggcggtatat tgcttatgta agcatttaca aaggctagtt agtgcttttt ttatttttag
    13741 taaaccagtt tactaaagtg gtttaccttt cctaaaaata atgtataata ccgaatgaag
    13801 acaaggagga tcaggcaatg cgaatggtgg atctgattga aaaaaagagg gatggaaacg
    13861 agctgtcgaa agaggaaatc gagtacatcg tcacgaacta tacgaatgga aagattccag
    13921 attatcaagt cagtgcatta ttgatggcaa ttttttatca agacatgaca aatgaagaaa
    13981 tcacgaactt aacattggcg attgctaatt ctggtgatgt catcgatttg agttctcttg
    14041 aaggaataaa ggtagataag cattcgacag gtggcgttgg tgacacgacc acattgattt
    14101 tagcccccct agtagctagt gtcggagtga cagtggctaa aatgtctgga cgcggtctag
    14161 gttacacagg tggtacacta gacaagctag aagcaattcc cggatttcag atcgagcttt
    14221 cggatgaaga atttgtacgc attgttaatg aaagtaaagt agcggtaatt ggtcaatcag
    14281 gaaacttggc accggcggac aaaaaattgt atgccttgcg tgacgtcaca gcgaccgttg
    14341 attctcttcc gctgattgcc agttcgatta tgagtaaaaa aatcgcggca ggagcagatg
    14401 caatcgtttt ggatgtgacc actggagacg gtgctttcat gaagaacatc gaagatgcaa
    14461 gacgtctggc aaagaccatg acgagcattg ggaaactggc taaccgagaa acagtggcgg
    14521 ttatctcaga tatgtcagaa cctcttggcg aagctatcgg aaatagtcta gaagttgtcg
    14581 aggcaatcga aacattacaa ggaaatggtc cagaagatct agtagaaatg tgctacgcct
    14641 taggaagcca aatggttgtt cttgctggca aagctaagac aaccgatgaa gcaagaacgt
    14701 tgcttcaaga agctctggaa tcaggtaaag cgttagcaaa attcaaagaa atgatccaaa
    14761 atcaaggggg agacccagcg atcgtggaac atccagaacg aattttgact gcacgctaca
    14821 caatggagct tcctgctaaa caaagcggag ttgtgtcaaa aatcgtggca aatgaattag
    14881 gaattgctgc aatgatgcta ggtgctgggc gtaaaaccaa agaagaagat attgatcacg
    14941 ctgttggatt gaaactgcat aaaaaaattg gtgacactgt gacaaaaggt gagtcactat
    15001 tgacgatcta tagtaacgac gaagaaatca cttctgtcat tgaattatta tataaaaata
    15061 ttgaaattgg tgaatcggca atgaagccaa cgttgattca tgacatcatc acagaataaa
    15121 ggaaaaaagc ggactttacc gttttaaaga aaaggggaaa agaaatggaa ctaaaccgaa
    15181 tgatcgacca tactattttg aaagcagacg catctaaaga agctgtgatg caaattatcg
    15241 aagaagcaaa aaaataccat ttttattctg tctgcatcaa tccagcatgg gttgcgctag
    15301 cgaaagaaca attacaaggt gagccagtag ccgtatgtac agtaatcggg tttcctctag
    15361 gagcaaacac acccgagaca aaagcatttg aaacaacaga tgccatcaat aacggtgcag
    15421 atgaagtcga tatggtcatc aatatcggtg ctttgaaatc aaaggatgat caacaagtcc
    15481 aaaaagatat cgaagcagtt gttgaagcag caaaagatcg tgcgcttgtc aaagttatta
    15541 ttgaaacatc gttattagat agagaagaaa tcatccgagc ttgcgaaata gcaaaagctg
    15601 caggcgctga ttttgtcaaa acatcaactg gtttctcaac aggcggagca aaggtagagg
    15661 atgtccgttt gatgcgtgaa actgtaggac cagaaatggg tgtcaaagct tccggcggta
    15721 tccataacga agaagaagca atggcaatga tcgaagctgg tgctacaaga atcggaacaa
    15781 gcgcaggagt agcaatcgta tctggttcaa ctggtgaagg ctattaattt tttcaaagga
    15841 gaagctcatg gcagaactca aacaagaatg gatcaacaca gctattgaag cgttagataa
    15901 agcctatgtt ccttattccc attttccggt aggcgcttgt ctcgtaacgg aatcaggcaa
    15961 gatttatcaa ggcatcaaca ttgagaatgc atcatttgga ttaacgaatt gtgccgagcg
    16021 cacagctttt ttcaaagcag tatctgaagg agaaaaaaca tttacgcatc tagtcgtagc
    16081 ggggcacacc cccgatccta tctctccttg tggtgcatgt cgacaagtaa tggcagaatt
    16141 ctgttcccct gatatgccgg ttacgctagt aggagacaat ggtgtgacga aggcaacgac
    16201 cgttcgtgca ctgctgcctt atgcatttac tgaaaaagat ctataactca tgttcattca
    16261 gtcagctgac tgttgaaaaa taaaacaatt attttaggag gctttacaga aatgaaaaaa
    16321 gcaaaattat ttggtttagg tgctgtcgca ctagcagcag ggttattttt aggtgcatgc
    16381 ggcaacaacg gctctactga ttcatccggt ggcaaaagct catcagacac aacaactgca
    16441 gcattgatca cagacacagg tggtgtagac gaccgttcat tcaaccagtc agcttgggaa
    16501 ggactagaaa aatgggggaa agatcaagga ctttcacgag gaaatgatgg cttccaatat
    16561 ttccaatctt caaatgaatc agattacatc ccaaatattg accaagcatt gaatgctgga
    16621 ttcaaaacga tttttggtat tggttataaa ctaaaaccag cgatccaaga acaagcaaca
    16681 aacaatacag gtacgaactt tgttattatc gatgatgtca tcgatggatt agataacgtt
    16741 gtatctgcaa ctttcaaaga caacgaagct tcttatcttg caggtgttgc agcagcttat
    16801 acgactgaaa caaacgtagt cggctttatc ggcggtgtaa aaggtgaagt aatcgatcgt
    16861 tttgatgctg gattcaaagc cggtgttgat gcaggtgcga aagaattagg aaaagaaatc
    16921 aaagtattga atcaatatgc tggtgacttc tctgctccag ataaaggacg ttcaattgct
    16981 caaggtatgt atgcacaaaa cgcagatatc atcttccatg cttcaggcgg tacaggtaac
    17041 ggtgtattcc aagaagcaaa atcattgaac gaatcaggcg acaaaaaagt ttgggttatc
    17101 ggtgttgacc gcgaccaatc agacgaaggc gaatacacat taaacggcga aaagaaaaac
    17161 ttcacattga catctacact gaaagcagtt ggaacagtag tagaagattt ggcacaaaaa
    17221 tcagcggacg gtaaattccc tggcggcgaa cacactgttt atggattgaa agaagacggt
    17281 gttggtctaa cagaaggaca actttctgac gaagcgaaaa aagcagttga tgaagcaaaa
    17341 gaaaaaatca tttcaggtga cgtaaaagtt ccagaaactc ctgaagaaaa ctaaaaccat
    17401 ttctatagcc ttgttagaca catgtttgac aaggctatgg tttgattaga acaagaattg
    17461 ttcatttatc caagctgcct tgtgacagtt tggataaggg aacaactccc tgaagtaatg
    17521 tttgtttcaa aagaagaacg ctcactaagc gtgaatctta gtcaatcgtt gccctagata
    17581 gaaatcgtta ggatgtgaaa aaaaggtggt tcaagaaaat attgtcatag aaatgcagaa
    17641 tattaccaaa gaatttggaa cattcaaggc aaatgacaac atcaatttac aagtaaaggc
    17701 aggagaaatt catgcgttgc ttggagaaaa cggtgctggc aaatctacat tgatgaacgt
    17761 gctttccgga ttattagagc cgacatcagg gaaaattttg atgcgtggga aagaagtaaa
    17821 gatcacaagt ccgaccaaag ccaaccaatt agggattggg atggtccatc agcactttat
    17881 gcttgttgat gcctttactg taacagaaaa catcgtgttg ggaagcgagc ctagtcgcgc
    17941 agggatgctt gaccataaaa aagcacgaaa agagatccaa aaagtttctg aacagtatgg
    18001 attgtcagtc aacccagatg cttacgttcg tgatatttca gttggaatgg aacaacgggt
    18061 agaaatttta aaaacacttt accgaggagc agatgtactg atttttgatg agccgacagc
    18121 tgtattgacc cctcaagaaa ttgatgaatt aatcgtgatc atgaaggaat tagtcaaaga
    18181 aggcaagtcg atcattttga ttacgcataa gttagatgaa atcaaagcag tagctgaccg
    18241 ctgtacagtt atccgccgtg gaaaaggaat cggtacagtc aacgttaaag acgtaacctc
    18301 acaacaatta gccgatatga tggttggaag aacggtttca ttcaaaacga tgaaaaaaga
    18361 agcgaagcct caagaagtcg ttttgtctat tgaaaatcta gtggtgaaag aaaatcgtgg
    18421 attagaagcc gtgaaaaact tgaacttaga ggttcgtgct ggcgaagtac ttggtatcgc
    18481 tggaatcgat ggaaacgggc agtcggagtt gatccaagct ttgactggtt tgcgaaaggc
    18541 agaaagcgga catatcaagc taaaagggga agacatcact aataaaaaac cccgaaaaat
    18601 cactgaacat ggtgtaggac acgtgccaga agaccgtcat aaatacgggt tagtcctaga
    18661 tatgacatta tctgaaaata tcgcactaca aacctatcat caaaaacctt acagtaaaaa
    18721 cggcatgctg aattattcag taatgaatga acatgccaga gaattgatcg aagaatatga
    18781 tgttcgaaca acgaatgaac ttgttcccgc aaaagcttta tcaggcggaa atcagcaaaa
    18841 agcaattatc gctcgtgaag tcgaccgaga tcctgatctg ttgattgttg caaatccaac
    18901 tcgtggactg gatgtaggtg cgatcgaatt tattcataaa cgtctgatcg aacaaaggga
    18961 caaatacaaa gcagtgttac tgatcagttt cgaattagaa gaaattttaa atgtttcgga
    19021 tcgtattgct gttatccatg aaggagaaat tgtcggtatc gttgatccga aagaaacatc
    19081 tgaaaatgaa ttaggtctat tgatggcggg ctatacctta gaagaagcac gaaaagagtt
    19141 agaaaagggg gctggcgcac atgaatgatc gcagcgaaaa attccgtaat ttattagtgc
    19201 ctgtactttc agttgtttta ggattgatct taggcgcgat attgatggct gcttttggtt
    19261 ttcagcccat ccaaggttat tcttctatgc tagatgcagc ccttggttcg caaagaggga
    19321 taggtgaaac gttaaggcaa gcaacgccgt tgatttttac agcattaggt ttttctgtag
    19381 ctaactcagc tgggtttttc aatattgggc tttctggaca agcactttgc gggtggatcg
    19441 tcagtgtctg ggtggcactt gcgtttccag atctgccaaa agttgttttg cttccgttat
    19501 gcgtgatctt aggtgcctta gctggtgcga tggcagcggc tgttccaggt ttacttcgag
    19561 cattttttgg aacaagtgaa gtgatcgtaa caatcatgat gaactatatc ttattatacg
    19621 taagcacatt tgctttacat gaagtgatgc ctgaaagcta tcgctcaagt ttggactctt
    19681 ccaatatgat cagtcaaaat gcctcactgc ggttaccatg gttaacacaa gcttttggcg
    19741 gctctcgcgt aaactcagga ttatttttag caatcatcgc gcttattttc gtttggctgc
    19801 tgatgaagaa aacgacttta ggatttgaaa tccgttctgt tggattgaat ccttttgctt
    19861 ctgagtatgc aggaatgagt agtaaacgta cgatcgtttt gtcgatggtc atttctggcg
    19921 ctttggcagg gcttggcggt gtggttgaag gattaggaac gtatcaaaac ttctttgttc
    19981 aaacgacttc gctatctatt ggatttgacg gaatggctgt ttccttgctt ggttctggat
    20041 cagcaatcgg tattctttta tcagcgatct tgttcagtat tttgaagatc ggtggacttg
    20101 gcatgcagac aggagcaggt gttccgtttg agatcgtcaa tgtatcgatt gctttgatta
    20161 tcttctttgt cgggatcaac ttcctgattc gtttcgtcat ggctaaagtc ttccaaggga
    20221 aaaaacaaga agagatcgtt gcgacaatag aatcgaaacc aacgaatcaa aaccatgaag
    20281 ggggcgaact ataatgtcga ctatcgaatt aattgccttg atccttactt ctacactggt
    20341 ttattcaaca ccgctaattc taacgtcact aggcggaact ttttctgaac gaagcgggat
    20401 cgtaaacgta gggctagagg gaatcatggt catgggtgct tttagttcca tcgttttcaa
    20461 cttgacgatg agtccatcac ttggttctat gacaccatgg atcgctattt tagtgggtgg
    20521 cgtcgtaggt atcctatttt ctctgattca cgcagtagca acagtcagtt tgcgtgctga
    20581 ccatattatc agcgggacag taattaatct gatggcacct gctttaggtg ttttcttgat
    20641 caaagcatgg tatggtaaag gtcaaactga taacatcacg cagaatctgg ggtatttttc
    20701 tttcccagga ttagcagata ttccggtcat tggaccaatt ttctttaaaa atacattctt
    20761 acctgcttat tgtgctattt tgattgctgt cctagcttgg gtgatcatct tcaagacgaa
    20821 attcggcttg cgcctccgtt cagttggtga aaatcctcaa gctgccgaca cattaggtat
    20881 caatgtatat gctatgcgtt attcaggcgt actgatttct ggcttgttag gcggtatggg
    20941 cggtgctgtt tttgctcagt cgatttccgg taacttttca gctggtacga tcgttggaca
    21001 agggttcatc tccatggctg ctatgatctt tggtaagtgg aatcctttag gggcaatggg
    21061 tgcctcattg ttctttggtt ttgctcaaag cttgagtatc attggcgcac aattaccagt
    21121 tatttcttcg attccgccag tattgctgca aattgctcca tatttgctga caatcattgt
    21181 gctggttgtt ttcttaggga aagcttctgg tccaaaagca aacgggaaga actatatcaa
    21241 atcaaaataa tcttttagcg aataaaaagg gtgggttacg ggaagtgttt ttcgtctcgc
    21301 cctttttgtt ttaaaggcaa taaaaataaa aagaaagaag gaataatcat gtttaaacgc
    21361 gtacatctga tcgtcatgga ttcagtagga attggagaag caccagatgc cgataagttc
    21421 ggtgatgttg gttctgatac attaggacac attgcgaaag aagcaggatt gaacgttcca
    21481 catttagagc agcttggttt aggaacgatc cgtcctcttg aaggtgtgga atcagtgaaa
    21541 gatcatcaag gctatgcgac gaaattagaa gaagtttctg tagggaaaga tacgatgaca
    21601 ggccactggg aaatcatggg attgaatatc aaaactccat ttcgtgtgtt tcctaatgga
    21661 ttccctgatg atctgatcaa acaaatcgaa gaattttctg gccgtaaagt cgtatgtaac
    21721 aaaccttata gcggaacagc tgttattgac gattacggtg aacaccaaat gaaaacaggc
    21781 gatttaattg tatatacttc tgccgatcct gtccttcaga tcgcggcaca tgaagaaatc
    21841 attcctttag aagaattata tcggatttgc caattcgttc gtgatataac aaaagatgat
    21901 ccgtatatga ttggccgaat cattgcacgt ccgtacgtgg gtgaaccagg agacttcaca
    21961 cgaacaagca atcgccatga ttatgcgttg aatccattcg gacacacagt ccttgattct
    22021 ttgaaagaag caggaaagga cgtgattgct gttggaaaga tcaacgatat tttcaacgga
    22081 caaggaatca ctgaatctgt ccgcacgaaa agcaatatgg atggcgttga ccagctgctg
    22141 aaagttatga aaaacgattt ttcaggaatc agctttacca atttagtaga ttttgatgca
    22201 ttatacggtc atcgtcggga tgtagtcggc tatgcgcatg cgattgaaga atttgactta
    22261 cgaattccag aattgcttga agcgatggaa gaagacgact tgctaatgat tacagccgat
    22321 cacggaaacg atccgacgtt tactggtacc gatcatacgc gagaatatgt accgttattg
    22381 gtttacagta aaaaaatgaa agaacaaggg gcattgcctc aaggatatta ttcagatatt
    22441 tcagcaacga ttgctgagaa ctttagtgtt tcttcgactg aaaatggcga aagcttcttg
    22501 aaattattaa aataatcttt ttaaatagga gaaagcaaat gaccaagtta agcgagatgt
    22561 tacaagaaac gacccagttt atccttgata aaggagtaaa agaaattgat tttggtttga
    22621 ttctaggttc aggattaggt gaattagcag atgaaatcga agatgctgta atgatttctt
    22681 atgatgagat cccgttcttt cctgtttcga cagtagttgg gcatgcagga aagctagttt
    22741 atgggtctct ggcaggcaag aaagtgttag ccatgcaagg gagattccac tactatgaag
    22801 gtcattccat gcaaacagtg acctatccag tacgtgtgat ggccggacta ggggcccatt
    22861 cagtcattgt gactaatgca tgtggtggtg tcaacgaatc atttgtacca ggagatttga
    22921 tgctgattac cgatcatatc aattttactg gtgaaaatcc tttgatcggt ccgaatgaag
    22981 atgcaatggg ccctagattt ccagatatga gtcaagctta tacgcctgac tatcaagcaa
    23041 cagcaaaagc agcagcagaa aaactaggtt tggatcttaa agaaggcgta tatatgggct
    23101 attctggacc aacttatgaa acgcctgcgg agatccgaat gtctcggaca ataggagccg
    23161 atgcagtagg gatgtcgact gttccagaag tcatcgtagc agctcacagc ggattaaaag
    23221 tgttaggaat ctcttgtatt accaacttag cagcaggtat gcaagcgaat ctgagccatg
    23281 aagaagttgt agaaacaact cagagagtca aacaatcttt taaagcattg gttaaagaaa
    23341 cattgacatt attgtaatag gaggaacaat aaaatgagtg tgcatattga agcgaaagaa
    23401 ggcgagatcg ccgataagat tttacttccg ggagatcctt tgcgagctaa atatattgcg
    23461 gagacttttt tggaagatcc agtttgttac aatcaggtac gcggtatgtt aggctttacc
    23521 ggcaaatata aaggagaacg tatttctgtt caaggaacag gaatgggaat gccatcagcc
    23581 accatctatg cccatgaatt gatccagtcg tatggtgtaa agaaattgat tcgagtaggt
    23641 acatgcggtg cattgtcaaa agacgtccat gttcgtgatt tagtactagc acaaggtgca
    23701 gcgaccagtt cttcgatgat cgaaaaaaat ttccaagcct ttcattttcc tccaatcagt
    23761 gatttcaatc tattactgaa agcatatgag atagctaaag aaaagggcta tacggttcat
    23821 gtaggaaatg ttctttcgga agattctttc tacaaagatg atttgacaga gacgttccaa
    23881 ttagctgaac ttggcgtttt aggagtggaa atggaagcag cggctcttta ttacttaggc
    23941 gcgaaatacc atgtgcagac attaagtttg atgaccgtta gcgaccattt gatcaccggt
    24001 gaagaaacaa cagctgcaga acgtcaatct acgttcaatg aaatgatcga agtaggattg
    24061 gaaacagcga tagcagaata agaaggaaat gaaaaagctg ccctgcatta agtaataaga
    24121 acatccaagc aaaaatagct cctcatgttt ttgacttggc tggacttatt attgcaaatg
    24181 taagcttttg aacaccgttt accaagaggt tgtgaatctg ccgtttaact ctgagtcaca
    24241 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgaga
    24301 agttggcagg agaaaaccgt ttatacgaaa aaagggactg tgacaaatcg tgtcacagtc
    24361 ccttttttat agtgtttttt ataggtagta ttttttagca actgttaagt catcatttaa
    24421 ttcataaaca agtggttgac ctgttggaat ttcaagatcc atgatgtctt cgtcagagat
    24481 accttcgata tgtttagcta gggcgcgtaa tgagttacca tgtgcagcta ctaaaacagt
    24541 tttgttgtct agtaatgctg gagcaatttc atcttgccag aatggcaaag cgcgttctaa
    24601 tgtcactttc aagttttctc caccaggaat atcgcgtttg tctaacattg cgtaacgacg
    24661 gtcatttgct gcagaacctt cgtcagtttc ttccattaat ggaggaagag tatcgtaaga
    24721 acgacgccag atgtgcactt gttcgtcgcc gtatttttca gctgtttctt ttttgttcaa
    24781 accttgtaat ttaccatagt gacgttcgtt taagcgccat gatttgattt gtggtaccca
    24841 aagttgatct gaatattcta agatcaagtt acatgttttg attgcacgag ttaaaacaga
    24901 agtgtaagca acatcaaatt cgattccagc ttctttgatt ttgcgtccgc cttcttttgc
    24961 ttcttcgatt ccttctggtg ctagatttac atcagcccaa ccagtaaatt ggttcaatgc
    25021 attccattca ctaagaccgt gacgagaaaa aactaatttt ggcatgttta gctctccttt
    25081 taagataggt ttatatttct gaaattttca gttctgtttt attgtacaat tttttggaag
    25141 agatttccat cgaaaaatta gataagattc tatgagaaaa caagtagaga atataaaaaa
    25201 acgaacagtg cccacgcaac tgttcgtttt taggtattag atgcataatt gctcgatttc
    25261 tttttcaggt aaattgatat atttataaca tgttccaact gaaacaccgc attttgaaga
    25321 aataaattgg atcgtttctt ttttttcata atagagacgt cggatttttt tgatcgtttt
    25381 tgcatcgatt tttggtcttc cgccgatttt tcctttttta cgagcttcat ctaatccaac
    25441 taatgtacgt tctttgatca atgcgcactc catgtttgct aggttttcca ttaattggaa
    25501 atagattttt cccatttcgc gcgtatcgat tccttcatca agactaatca agtgcagccc
    25561 gcgatctttg aataattgcg tgagttctgt taattgccgc gtagatttgc ctaatcgatg
    25621 aagttggcaa atgactagtg catcgccttg ttgcatgtca gcgatcactg actccaaatg
    25681 aacagcagta gaatcatttt gttccacttc atatgtctca tggaaaattt cttgacaacc
    25741 aaagtcagat aattgatcaa cctgagttgt taaatcaacg tcatttatgg ttgtgcgtgc
    25801 ataaccaata attttcatgg tgattccttt ctagcagtga ttttctaact ggatataaca
    25861 gtaaaaatgt agcataaagt acgtcaaaaa gatagttttt tcgcaaattt tccgctgtct
    25921 ttttttattg gatgatcaag cagtttttct ttatttacga cggattgcgt caagaatctc
    25981 aacgcctttt tctgagccga caactacttt agaaaccatg tttaggaaaa gcccatgttc
    26041 tactacccca acaagttcat ctaaataggt agctaagctt tctggctgtt cgatgacttc
    26101 tagatgcaga tcaatgatgt aatgaccacc atctgtggtt aagacttctc cgttttcgtc
    26161 tgtacgcaag acgggttgga atcttttttc ttcaaaaata tgaagtagct gttgggagcc
    26221 ataagggatc acttcaactg ggagtgggaa cttcccaagt ttatcgacta atttagaaga
    26281 atcaacgatc caaatcgttt cttttgagta cgtagcgact attttctcga aaagcaaagc
    26341 agcgccgccg cctttgatcc cttgaaaatc agcactgatt tcatcagcac cgtctattgt
    26401 caaatcgact acggggactt catcaatact ctttaacggt attcctaatt tttccgcttg
    26461 ttcttttgtc gcatttgaag tagtaactcc tgtgatacgt aaaccttctt cacgcatacg
    26521 gcgaccaatc tcttctacca tataataggc ggttgaaccg gtcccgagac ctacgatcat
    26581 cccgtccttt acgaatttcg cggcttcaat gccagctaat tgttttaaat tcatctttgc
    26641 gtccaccttt ttttagtttg agcatcgtgc tttcctcact attttagcgt gatttacggt
    26701 aaaaagatac cattcttttt tattccaata aagctttttc aaaaaaaatt gcatctcttg
    26761 ttgacatgtt ttttcattcg tgatattcta acaaaggtgc tttatctaca ggtttctgtg
    26821 aagaaacgtg ctgactgttt atcaaagcat atttgataag gatgcagaca ttgcatttat
    26881 tttttatcac aaaaaaagaa ccacctggat gtgtggaact agacgcaaat cgtgggaagg
    26941 aggaaacaag gaatgcctac aattaaccaa ttagtacgta aacctcgtaa atcaaaggtg
    27001 gaaaaatcta attcacctgc tttgaacaaa ggatataaca gctttaagaa aactcaaact
    27061 aacgtaaact cacctcaaaa acgtggggta gcaactcgtg tgggtacaat gacacctaaa
    27121 aaaccgaact cagctttacg taaatatgca cgtgttcgtt tgtcaaactt aattgaagtt
    27181 actgcttata tcccagggat tggtcataac ttacaagaac acagtgttgt attattacgc
    27241 ggtggtcgtg taaaagactt accaggggta cgttaccata tcgttcgcgg tgctttagat
    27301 actgctggtg ttaacgaccg taaacaaagc cgttctaaat acggaactaa aaaacctaaa
    27361 gcttaatttt aattattaaa caaatgaaac ttgcttctac tatatagaag taattactat
    27421 gaacaatatt tcggaaggag gagttacgga tgccacgtaa aggtcctgtt gcaaaacgtg
    27481 atgttttacc agatcctatt tataactcaa aattagtaac tcgcttgatc aaccgtgtaa
    27541 tggttgacgg aaaacgcggg attgcagcta acattatcta taatgccttt gacttgatca
    27601 aagaatctac aggtaacgat ccattagaag tgtttgaaca agcaatgaaa aacgttcaac
    27661 ctgttcttga agttaaagca cgtcgtgttg ggggttcaaa ctaccaagta ccagttgaag
    27721 ttcgccctga acgccgcgtt actctaggtc ttcgttgggt agtaaactac gctcgcttgc
    27781 gcggtgaaca cacaatggaa gaacgcttag caaaagaaat catggatgct gcaaacaaca
    27841 caggtgcttc tgttaaaaaa cgtgaagaca ctcataaaat ggctgatgcc aaccgtgcgt
    27901 ttgctcacta tcgctggtaa gattctctct gtttggtcgg cttttataag tcgacctcag
    27961 atagtgtcct tatttttagc aactagatag taaagagagg agaaacaagg agaatgacca
    28021 gagaattttc tttacaaaac actcgtaata tcggtatcat ggcccacatc gatgctggta
    28081 aaacgactgc tactgaacgt atcttgtact atactggtaa aatccataaa attggtgaaa
    28141 ctcatgaagg agcttcacaa atggactgga tggaacaaga acaagaacgt ggtattacga
    28201 tcacttctgc tgctactaca gcacaatgga agggtcaccg aatcaacatc atcgacacac
    28261 caggacacgt agacttcaca gttgaagttg aacgttcatt gcgtgtactt gatggtgctg
    28321 taactgttct tgatgcacaa tcaggtgttg aacctcaaac tgaaacagtt tggcgtcaag
    28381 caacaactta tggtgtacct cgtatcgtat ttgcaaacaa aatggacaag atcggtgctg
    28441 acttcttata ttcagtatca actttacatg accgtttgca agcaaacgct cacccaatcc
    28501 aattaccaat tggtgcggaa gacgacttca caggaattat cgaccttgta acaatgaagg
    28561 ctgaaatgta tacaaacgat cttggaacag agatcgaaga aacagaaatt cctgaagaat
    28621 accgcgaatt agctgaagaa tggcgcgaaa aattggttga agctgtagct gaaactgatg
    28681 aagaacttac tttgaaatac ttagaaggtg aagaaatcac tgaagctgag ttaaaagaag
    28741 gtatccgccg cgcaacagtt aacgtagaat tctacccagt actatgtggt tcagcattta
    28801 agaacaaagg ggttcaatta ctattggacg ctgttcttga ttacttgcca tcaccgttag
    28861 atatcccagc tatcaaaggg attgacccta aaactgatga agaagtagaa cgtcctgcag
    28921 acgacagcgc tcctttctca gctttagcat ttaaagttat gactgaccca ttcgtaggtc
    28981 gtttaacttt cttccgtgtg tactctggtg ttttacaatc aggttcatac gtacaaaacg
    29041 caacaaaagg caaacgtgaa cgtgttggtc gtatcctaca gatgcatgcc aactctcgtt
    29101 cagaaatctc tgaagtttac gctggagata tcgctgctgc tgttggtttg aaagacacaa
    29161 ctactgggga cacactatgt gatgaaaaga gtctagttat tcttgaatcc atggaattcc
    29221 cagaaccagt tatccaagtc gctattgaac ctaaatcaaa agctgaccaa gataaaatgg
    29281 gtgtggcttt acaaaaacta tctgaagaag atcctacttt ccgtgctgaa acaaacgtgg
    29341 aaacaggcga aacaatcatc gctggtatgg gtgaacttca cttagatatc atcgttgacc
    29401 gtatgcgtcg tgaattcaaa gttgaagcta acgtaggtgc gcctcaagta tcttaccgtg
    29461 aaactttccg tgctggcact caagccgaag gtaagtttgt acgtcagtct ggtggtaaag
    29521 gtcaatacgg tcacgtatgg attgaattta caccaaatga agaaggtgct ggtttcgaat
    29581 ttgaaaatgc gatcgtcggt ggggttgttc ctcgtgaata cattccagct gttgaaactg
    29641 gtttgaaaga tgctatggaa aatggtgtct tagctggcta tccattagta gatatcaaag
    29701 ctaaacttta cgatggttca taccatgatg tcgattcaaa tgaaactgcc ttccgtgttg
    29761 ctgcttctat ggcattacgt gcagcagcta agaaagctaa tccagtaatc cttgaaccaa
    29821 tcatggctgt agaagttgtt atccctgaag attatttagg tgatgttatg ggtcacgtaa
    29881 ctgctcgtcg tggacgtgtt gaaggtatgg aagctcgcgc tggcggccaa caagttgttc
    29941 gtgcgatggt tccacttgct gaaatgtttg gttatgctac aactcttcgt tctgctactc
    30001 aaggtcgtgg tacatttaca atgacatttg accactacga agatgtacca aaatcagtac
    30061 aagaagaaat cattaagaaa aacggcggaa aagctgaata atttcttaaa accggatagt
    30121 cctgcaaaga gattatccaa agagactata tttttaatat agtttcgtgt aaaataatta
    30181 tcgatgatat gggcatgtgg tgtaccttgt gtacatcata tacctatcag acaaataaaa
    30241 aatatattgt atttttagga ggacatttta aaatggcaaa agaaaaattt gaccgttcta
    30301 aaccacacgt taacattggt actatcggac acgttgacca tggtaaaact acattaacag
    30361 ctgcaatcac aactgtacta tctaagaaaa acggcggcca agctatggct tacgatcaaa
    30421 tcgatggtgc tccagaagaa cgcgaacgcg gaatcacaat ctcaacagct cacgttgagt
    30481 atgaaacaga tacacgccac tacgctcacg ttgactgccc aggacacgcg gattacgtta
    30541 aaaacatgat cactggtgct gctcaaatgg acggagctat cttggtagtt tctgctgctg
    30601 acggcccaat gcctcaaact cgtgaacaca tcctattgtc tcgtcaagtt ggtgttcctt
    30661 acatcgttgt attcttgaac aaagtagaca tggttgatga cgaagaatta ctagaattag
    30721 ttgaaatgga agttcgtgac ctattaacag aatacgaatt ccctggtgac gatgttcctg
    30781 tagttgctgg atcagctttg aaagctctag aaggcgacgc ttcatacgaa gaaaaaattc
    30841 ttgaattaat ggctgcagtt gacgaataca tcccaactcc agaacgtgac aacgacaaac
    30901 cattcatgat gccagttgaa gacgtgttct caattactgg acgtggtact gttgctacag
    30961 gtcgtgttga acgtggacaa gttcgcgttg gtgacgaagt tgaagttgtt ggtattgctg
    31021 aagaaacttc aaaaacaaca gttactggtg ttgaaatgtt ccgtaaattg ttagactacg
    31081 ctgaagctgg agacaacatt ggtgctttac tacgtggtgt tgcacgtgaa gacatccaac
    31141 gtggacaagt tttagctaaa ccaggtacaa tcacacctca tacaaaattc tctgcagaag
    31201 tatacgtgtt gacaaaagaa gaaggtggac gtcatactcc attcttcact aactaccgtc
    31261 cacaattcta cttccgtaca actgacgtaa caggtgttgt tgaattacca gaaggaactg
    31321 aaatggttat gcctggcgac aacgtaacaa tggaagttga attaatccac ccaatcgcta
    31381 tcgaaaacgg tactaaattc tcaatccgtg aaggcggacg tacagttggt gccggtgtcg
    31441 ttacagaaat caaagcttaa ttcacttaag ttttaaagta aagcaacatt tattcggacg
    31501 taatcgctcg gaacgaaggt cttaggatct ttgttccgag cttttttatt tattgcagga
    31561 tcaggaaaaa agacaggagt attataaata gaagaaacac gaaataaaag agtcagtatt
    31621 ttctaaatga aactttatga aaacaaaatg ttttttacaa gaaaaagcct tgctttgtga
    31681 gtttatatat attataatga caaaggtgcg tttactttag tgaattgcac agacgtaatc
    31741 agaatgattt cgtcggctaa gaaacgagag gttgcgacac gcccggacgc tttgccacga
    31801 acgagcgtga cggaaatttt cgtggagcta tgtctacttt tcaaaatagg cgaaggaggg
    31861 aacaagatgg caaaacaaaa aattcgtatc cgtttaaaag cgtatgaaca ccgtatttta
    31921 gatcaatcag cggataaaat cgtggaaact gcaaaaagaa ctggagctag cgtgtctggt
    31981 ccaattccat taccaactga acgcagtctt tacacaatca tccgtgcgac tcataaatac
    32041 aaagattcac gcgaacaatt cgaaatgcgt acacacaaac gtcttatcga cattgtgaac
    32101 ccaacaccaa aaactgttga tgctttgatg aagctagact taccatctgg tgtaaacatc
    32161 gaaatcaaat tataaaacta aaacaaaaat aatggaggtg tactcatgac caaaggaatc
    32221 ttagggaaaa aagtgggaat gacacaaatc ttcactgaat ctggtgaatt aattccagta
    32281 actgttgtag aagctactcc aaacgtagta ctacaagtga aaacaatgga aacggatggc
    32341 tacgaagcta ttcaagttgg ttaccaagat atgcgtgaag ttttatcaaa caaacctgcg
    32401 aaaggtcatg ttgcaaaagc aaacacggct cctaagcgct tcattcgtga attcaaaaat
    32461 gttgagctag gagaatatga agtaggaaaa gaaattacag tagatgtttt ccaagcagga
    32521 gacattattg atgtaacagg tactacgaaa ggtaaaggat tccaaggggt tatcaaacgc
    32581 cacggacaaa gccgcggacc aatggctcac ggttctcgtt accatcgtcg tcctgggtca
    32641 atgggtccag ttgcacctaa ccgtgtattt aaaaacaaac gtcttgctgg ccgtatgggt
    32701 ggcaaccgcg taactatcca aaacttggaa gttgtacgtg tcgatgcaga aagaaatgtt
    32761 atcttgatca aaggtaatgt tcctggagct aaaaaatctt taattactat caaatcagct
    32821 gtgaaagcta aataattgta ggaagaaagg aggaactaag gaatgccgaa tgtagcatta
    32881 ttcaaacaag atggaagcca aaacggtgaa atcacactta acgaagaaat cttcggaatt
    32941 gaacctaatg aaagtgttgt ttacgatgca atcgtaatgc aacgtgcgtc attaagacaa
    33001 ggaacacacg cggttaaaaa ccgtagcgct gttcgcggcg gcggacgtaa accatggcgt
    33061 caaaaaggaa caggtcgtgc acgtcaagga tctatccgct caccacaatg gcgtggaggt
    33121 ggcgtagtct ttggaccaac accacgttct tacagctaca aacttcctaa aaaagttcgt
    33181 cgtttagcaa tgaaatctgt attgtcagaa aaagttgctg aaaacaactt ggtagcaatc
    33241 gaaggcttga acttcgacgc accaaaaaca aaagaattca aacaagttct tgctaactta
    33301 tctatcgact ctaaagtatt ggttgttcta gaaaaaggta acgactttgc tgctttatca
    33361 gcacgtaact taccaaacgt ttctgtagta acttctgata atgtgagtgt gctagacgtt
    33421 gtatcaaata caaaagtgtt agcaacacaa actgctctta ctcaaattga ggaggtgctt
    33481 gcataatgaa cttactagac gtaatcaaac gcccagtgat cactgaaaaa tcaatgcttg
    33541 ccatggatga caagaaatac acttttgaag tggacactcg cgcaaacaaa actttagtaa
    33601 aacaagcggt agaagctgct tttgacgtta aagtcaaaaa cgtgaacatc gtgaacgtac
    33661 gtgcgaaatt caaacgtatg ggcaaatatg caggatatac aaaaaaacgt cgcaaagcga
    33721 tcgttacatt gactgaagat tcaaaagaaa tccaattatt cgaagctgct gaataagcac
    33781 taatagataa ctcattaaat taggagggaa aaacgtggcg attaaaaagt acaaacctac
    33841 ctcaaatggt cgtcgtaaca tgacaggttc tgattttgct gaaatcacaa catcaacacc
    33901 tgaaaaatca ttgttacaac cattgaaaaa ccatgctgga cgtaacaaca acggccgcat
    33961 cactgtacgt catcaaggtg gcggacacaa acgccaatat cgcgtgatcg acttcaaacg
    34021 taacaaagat aacgttgttg caactgttca aacgatcgaa tatgatccaa accgttcagc
    34081 taacatcgcg ttagtacact atgaagatgg agtgaaagct tacatcttag cacctaaagg
    34141 actagaagtg ggtatgaaac ttgtttcagg tccagaagca gatatcaaag tcggaaatgc
    34201 tcttccatta gaaaacattc cagttggtac tgttatccac aacattgaaa tgaaacctgg
    34261 taaaggtgga caattgatcc gttctgctgg tacaagtgct caagtacttg gtaaagaagg
    34321 caaatacgta ttgatccgct tgaactctgg tgaagttcgt atgatcttag ctgcatgccg
    34381 tgctacaatc ggttctgtag gtaacgaaca acacgaatta atcaacatcg gtaaagctgg
    34441 acgctctcgt tggatgcgta aacgcccaac tgtacgtggt agcgtaatga accctaatga
    34501 tcacccacac ggtggtggtg aaggtaaagc tcctatcgga cgtaaagcac cagtttctcc
    34561 ttggggtcaa ccagctcttg gttacaaaac tcgtaacaaa aaagctaaat cagacaaact
    34621 tattgttcgt cgtcgcaaaa ataaataatt actttgacca tgtgtcgcac attttgagag
    34681 gaggttcacc atgggtcgta gtttaaagaa aggacctttt gtcgatgagc atttaatgaa
    34741 aaaagttgaa gctcaagcag gggttgaaaa gaaaaaagtt atcaaaactt ggtcacgccg
    34801 ttcaacagtt ttcccaagtt ttgttggata taccatcgca gtttatgatg gacgtaaaca
    34861 tgtaccagtt tacatccaag aagacatggt aggacacaaa ttaggtgaat ttgcacctac
    34921 aagaacttat cgtggacatg ctgctgacga taagaaaacg aaacgctaat ttgaggggag
    34981 gataaatcca aatggcagaa caaatcacat cagctaaagc aactgcaaaa acagttcgca
    35041 cttcacctcg aaaagcccgt ttagtaattg accttatcag aggtaaaagt gtcgcagatg
    35101 caatttcaat cttgaaattc acaccaaaca aatctgctgg aatcattgaa aaagtattga
    35161 tgtcagcagt tgcgaatgca gaaaataact ttgacttaga tgttgaaaac ttggtagtaa
    35221 gcgaagcttt tgttaacgaa ggacctacaa tgaaacgttt ccgtcctcgt gcaaaaggat
    35281 cagcttctcc aatcaacaaa cgtacaagtc atatcacggt agtcgtatca gaaaaataag
    35341 gagggataat cagtgggtca aaaagtacat ccaattggaa tgcgtgtagg catcatccgc
    35401 gactgggatg ctaaatggta tgctgaaaaa gagtatgctg agttcttaca cgaagattta
    35461 agaatccgta aatttatttc aactaaactt gctgatgctg ctgtatcaac agttgaaatc
    35521 gaacgcgcaa caggtcgcgt aaacatttca attcacacag ctaaaccagg tatggttatt
    35581 ggtaaaggcg gttctgaagt cgaaagccta agaaaagaat taaacaaatt aactggtaaa
    35641 agaatccata tcaatatcgt ggaaatcaaa aaaccagatc tagatgcaaa attagtaggt
    35701 gaaggaatcg cacgtcaatt agaaaaccgt gttgctttcc gtcgcgctca aaaacaagcc
    35761 atccaacgct caatgcgtgc tggcgctcaa gggatcaaaa ctcaagtatc tggtcgtcta
    35821 aacggagcag atatcgctcg ttcagaagga tactcagaag gaactgttcc tcttcatact
    35881 ttacgtgcgg acattgatta cgcatgggaa gaagcagata caacatacgg aaaactagga
    35941 gttaaagtgt ggatctatcg tggagaaatt cttccaacta aaaaaaacac tgagaaagga
    36001 gggaaataat catgttagta cctaaacgtg taaaacaccg tcgtgaattc cgcggaaaaa
    36061 tgcgcgggga agctaaaggc ggaaaagaag tagcattcgg tgaatacggt ttgcaagctg
    36121 ttgattcaca ttggatcaca aaccgccaaa tcgaagctgc tcgtatcgca atgactcgtt
    36181 acatgaaacg tggtgggaaa gtatggatta aaattttccc tcacaaatct tatactgcca
    36241 aagcaattgg ggtacgtatg ggttctggta aaggggcacc tgaaggatgg gttgcaccag
    36301 taaaacgtgg taaaatcatg tttgaaatcg caggcgttcc tgaagaagta gctcgtgaag
    36361 cgttacgtct agcttctcac aaattaccaa tgaaaactaa gatcgtaaaa cgtgaggaaa
    36421 tgggtggtga atcgaatgaa ggttaaagaa atcagagaat taaccactgc cgaaatgctt
    36481 gatcaagaaa aacaattaaa agaagaattg tttaatctta gattccaatt agcaacaggt
    36541 caattagaaa acactgcacg tattaaagaa gtacgtaaat cgattgcacg catcaaaact
    36601 gtgttgcgtg aacaagctaa gtaattatgg aaggaggcca ttaagcgtat gactgaagga
    36661 agaaatcaac gcaaagttta tcaaggtcgc gtggtttcag acaaaatgga taaaacaatt
    36721 accgttgctg tcgaaacaaa gaaaaaccac cctatctatg gcaaacgcat gaactattct
    36781 aagaaataca aagtgcatga tgaaaacaac acagcaaaag ttggcgacat cgtgagaatt
    36841 atggaaactc gtccattatc agctacaaaa cgtttccgtt tgttggaagt agtcgaagaa
    36901 gcagttatta tctaataaca cgagattttc ctatatagat tgaatgcaaa atctgaaagg
    36961 aggatacaca acgtgatcca agcagaaagt cgtttaaaag tcgctgataa ctcaggcgca
    37021 cgtgaaattt tgacgatcaa agtccttggt ggatctggtc gtaaaactgc taacatcggt
    37081 gatgtgatcg ttgctacggt taaacaagca acgccaggtg gggttgtcaa aaaaggtgac
    37141 gtcgttaaag ccgttatcgt tcgaacaaaa tcaggagctc gtcgtacaga cggttcatat
    37201 attaaatttg atgaaaatgc tgcagtgatt attcgtgatg ataaaagccc tcgtggaaca
    37261 cgtatctttg ggccagttgc acgtgaacta cgtgaaaaca acttcatgaa gatcgtttca
    37321 ctagcaccag aagttttata atcttgagac acttatcaaa ggaggtgcga aacagttatg
    37381 tttgttaaaa aaggcgataa agttaaagtt atcactggaa aagacaaaaa caaagaaggc
    37441 gttgtactag cagcgttccc gaaaaaagat aaagttattg tcgaaggtgt aaatgtcgtt
    37501 aaaaaacacc aaaaaccttc tcaagctgct cctcaaggtg gaattgttga gatggaagcg
    37561 ccaattcatg tttctaacgt gatggtggtt gactctactg gtgtagctgg ccgagttggc
    37621 tacaaagaag tagacggcaa aaaagtccgt gtttctaaaa aaaccggtga agttttagat
    37681 aaataaaagt ttaaggaagg agggtcttac tgaatgaacc gcctaaaaga aaaatatctt
    37741 aaagaagtaa ctccatcatt gatggaaaaa tttaactata gctctgttat gcaaacacct
    37801 aaagttgaaa aaatcgtcat caacatgggt gttggtgatg cggtatcaaa cgctaaaaac
    37861 ttagataaag cagttgaaga attaactttg atcactggtc aaaaaccaat gattacaaaa
    37921 gctaaaaaat caatcgctgg attccgttta cgtgaaggaa tgccaattgg tgcaaaagtt
    37981 acattgcgcg gagaaagaat gtacgaattc ttagacaaat tggtttctgt ttcactacca
    38041 cgtgtacgtg acttccatgg tgtaagtaaa aaagcctttg acggtcgtgg aaactatact
    38101 ttaggtatta aagaacaatt gatcttccca gaagtagatt atgatttagt agataaagta
    38161 cgtggtatgg acatcgttat tgtaacaaca gcaaactctg atgaagaatc tcgtgagttg
    38221 ttgacacaat taggcatgcc attccaaaaa taattaaagg aggcgaacta cgtggctaaa
    38281 aaatcaatga ttgctaaaaa caaacgtcct gcaaaatttt caacacaagc ttatactcgt
    38341 tgcgaacgtt gcggacgtcc acattcagtt tatcgtaagt tccatctttg ccgtatttgc
    38401 ttccgcgaac ttgcctataa aggtcaaatt cccggcgtga agaaagctag ctggtaaaaa
    38461 gtaaattcgc ataagaagga ggtaaaagat caatggtcat gacagatcca attgcagatt
    38521 ttctaactcg tatccgtaac gcaaacatgg ttaaacatga gtctttagaa gtacctgcat
    38581 caaaaattaa acgtgacatc gctgaaatct tgaaacgtga aggtttcgtt cgtgatgttg
    38641 aatacatcga agatgacaaa caaggcgtga tccgtgtttt cctaaaattt ggtaaaaacg
    38701 gcgaacgtgt tatcacaaac ttaaaacgta tctctaaacc aggtttgcgt gcttatgtca
    38761 aagctgacga agtaccaaaa gtattgaacg gtttaggtat cgcaatcatt tcgacttctg
    38821 aaggtgttgt cactgataaa gaagctcgtg aaaaaaatat cggcggcgaa gttatcgctt
    38881 acgtatggta atcaagtaga atctacaagg aggtgtcttt aagtgagccg tatcggaaat
    38941 aaagtcgttg ttatccctga aggagtaaca gttactcaag acggaaacaa cgttacagtt
    39001 aaaggaccaa aaggtgaatt gactcgtact ttttcagcag atatcaaaat gaatatcgaa
    39061 ggaaacgaag taactttcac tcgtccaaac gacagtaaag aaatgaaaac aattcatgga
    39121 acaactcgtg cgaacttcaa caacatggtt gtaggtgtca gcgaaggttt ccaaaaagcg
    39181 ttagaactaa tcggggttgg gtaccgtgca caattacaag gatcaaaact tgtattgaac
    39241 gttggttact cacatccagt agaaatcaca ccaccagctg gagtaactgt tgaagtacca
    39301 gctaacacac aagtaattgt taaaggtgcg aacaaagaag aagttggcga attagctgca
    39361 aacattcgtg gaactcgtcc tccagaacct tataaaggta aaggtattcg ttatgttggc
    39421 gaatatgtac gccgtaaaga aggtaaaact ggtaaataat cgtttagaaa aattgcatag
    39481 aagccagcag caggaaaaag gcatttggct gaagtttacc ttcaaaaaaa tacattttta
    39541 cttgtgccgc agcttctatt tttcgaaacg tatttactgc ttgaaatagt agtacaataa
    39601 aaataaagag gtgacaattg tgattacaaa accagataag aacaaaacac gtcaaaagag
    39661 acatcgtcgt gtacgtaaca atatctctgg tactgctgag cgcccacgct tgaacgtttt
    39721 tcgttctaac aaaaacatct acgctcaaat tattgatgac gtagcgggtg taacgctagc
    39781 aagtgcctct accttggata aagaaatttc aggtggaaca aaaacagaag cagcacaagc
    39841 tgtcggtaaa ctagttgctg aacgtgcagc tgaaaaaggc attaaagtag tagtctttga
    39901 ccgtggtgga tacctttacc atggccgtgt gcaagcttta gctgaagctg ctcgcgaaaa
    39961 tggactagaa ttttagaaga aggaggaata ccattcatgg tttatatcga tccaaaacat
    40021 ttggaattag aagaccgcgt tgttgcaatt aaccgtgtaa caaaagttgt taaaggtgga
    40081 cgtcgtctac gttttgctgc tttagttgtt gtcggtgaca aaaacggaca cgtagggttt
    40141 ggtacaggta aagctcaaga agttcctgaa gcaatccgta aagcaattga agatgcgaag
    40201 aaaaacttag ttgaagtacc tatggttggt tcaacaatcc cacacgaagt aatcggtgct
    40261 tttagtggtg gtagaatcct aatgaaacct gctgtagaag gttctggggt tgctgctggt
    40321 ggaccagttc gtgccgtatt agaattagct ggggtagcag atatcacttc taaatcttta
    40381 ggctcaaata caccaatcaa cgttgttcgc gcaacagttg aaggtttgaa acaattgaaa
    40441 cgtgcagaag aagttgcaga acttcgcggc aaatcagttg aagaattaat cggataagga
    40501 ggacaacaat aatggctgaa ttaaaagtta ctttaaaacg cagtattatc ggacgtcctc
    40561 aaaaccaacg cgatacagtt aaagcgttag gtcttacaaa gattaacagt tcagtggtta
    40621 agccttctaa tgaagcaatt aaaggcatga tcaatactgt ttctcaccta gtggacgttg
    40681 aagaaattta atttagaaaa atcataacta gaacattaag gaggtgccaa acctatgaaa
    40741 cttcatgaat taaaacctgc tgaaggttca cgccaagtac gtaaccgtgt tggtcgtggt
    40801 acttcatctg gtaacggaaa aactgccgga cgcggacaaa aaggacaaaa agctcgttca
    40861 ggcggcggtg tgcgtttagg atttgaaggg ggacaaacac cattgttccg tcgtttacca
    40921 aaacgaggat tcacaaacgt gaaccgtaaa gactatgcag tcattaatct tgatgtattg
    40981 aaccgctttg aagacggagc tgaagtaact cctgttgctt tagttgaagc tggaatcgtg
    41041 aaaaacgaaa aagctggaat caaagtatta gctaatgggg aactaaacaa gaaattaact
    41101 gtgaaagcag caaaattctc taaagcagct caagaagcaa ttgaagcggc tggtggatca
    41161 atcgaggtga tctaatgttt agactattaa aagatgcttt taaagtaaaa gacattagat
    41221 cgaaaatcct atttactgta tttgtgttgt ttgtatttcg cctaggtgca catattactg
    41281 taccaggcgt aaatgctgct tcattgcaaa acctttcttc tttgccattt ttcaacatgt
    41341 tgaacttggt aagtggtagt gcgatgcaaa acttttccat tttctcaatg ggggtttcac
    41401 catacattac tgcttctatc gtcattcagc ttcttcaaat ggacatcgtg cctcgatttg
    41461 ttgaatggtc gaaacaaggg gaagttggtc gtaaaaaact gaatcaagcg actcgatatc
    41521 tgacattagt attggcattt atccaatctg tcggtatcac tgctggattc aatcaatacg
    41581 ctcaattagg tttcgtgaat aatcctaacg tagcaactta cgtaacgatc ggtttgattc
    41641 taacagccgg tacgatgttt gttacttggc taggagaaca gatcacagaa aaaggtatcg
    41701 gaaatggcgt atcaatgatc atttttgcag gtatcatttc tagattgcct gaaagtatca
    41761 gagaaattta tgaagattac tttataaata ttgatccttc agacatatgg aaatctgcta
    41821 tttttgtggc cattttacta gtagcggtct tgttgatcgt gacattcgta acatttttcc
    41881 aacaagctga acgcaagatc ccgatccaat atacgaaacg cgtagctggc gcgcctacaa
    41941 gcagctatct gccgttgaaa gtaaatgcag ctggagttat tccagttatc tttgctagtt
    42001 cgtttattgc tacgccaaat gctgttttac aagcattgag cggtagattc ggttctgaaa
    42061 actggtacaa agtgatgatg gagatcttta actataatac agcacctggt gctacgattt
    42121 atacgattct gatcgttgcc ttcactttct tctacgcctt tgttcaagta aaccctgaga
    42181 aattagcgga aaacttgcaa aagcaaggaa gttatatacc aagcgtacgc cctggtaagg
    42241 ggactgaaga gtatgtctca agattactga tgcgtttaag tacagttggt gcagtcttcc
    42301 ttggtttagt ggcattgctt ccaatcattg ctcaaatggt ttgggatctt ccacaatcaa
    42361 tcggattagg cggtacaagc ttactgatcg ttatcggtgt agctttagaa actgcgaaac
    42421 agttagaagg cttaatgctg aaacgtaaat atgttggatt cattgagtaa gaaagcgtgt
    42481 tgaggtttcc cctcaacaca cgttctcaca catttattag gagggaaaac aatgaacctc
    42541 attttaatgg ggctgccagg cgcaggtaaa ggaacacaag ctgaaaaaat cattgatgct
    42601 tatggtattc cgcacatctc aacaggagat atgttccgcg cagcgatgca aaacgaaaca
    42661 gctcttggcc tggaagcaaa gtcttatatg gataaaggtg cattagttcc tgatgaagta
    42721 acaaatggaa tcgtgaaaga gcgactagct gaaccagata cagagaaagg cttcttatta
    42781 gatggctttc cacgtacgct agatcaagca aaagctctgg acgcaatgct aaaagatttg
    42841 aataaaaaaa ttgatgctgt catcgatatc catgttggtg aagaaatctt ggtcgaacgt
    42901 ctagccggcc gatttatctg cagcaattgt ggagcaactt accataaaat tttcaaccct
    42961 acaaaagttg aagacacatg tgatcgttgc ggtgggcatg aattctatca aagagaagat
    43021 gataaacctg agacggttaa aaatcgtctg gctatcaaca tcaaaaatag tgaaccaatc
    43081 ttggcttatt ataaagaaca aggtttgcta aacactattg atggtgctcg tgaaatcgat
    43141 gctgtatttg cagatgtaca aaaaatcatt gaaaaatagc acgattgccc gtagccgact
    43201 tgcattatgc agttactctt gtcaagttca ataaattatg atagaatatg tcagtccgac
    43261 ttctagagaa tcctctagat gatccatttt gagaattttg aggtgggaac tgcagtttcc
    43321 gccattttat cgtgtgaaaa tgcgaaacaa gtacaaggag gtactgtgcg tggcaaaaga
    43381 agatatgatt gaagtcgaag gtacagtcgt cgaaactttg ccgaatgcaa tgtttaaagt
    43441 tgaactagaa aacggacacc aagttcttgc tactgtttca ggtaaaattc gtatgcatta
    43501 catccgtatc ttacctggtg acaaagtaac ggttgaattg tctccatacg atcttaaccg
    43561 tggccgtatt acttatcgct ttaaataatt gtactccgta aaactacagg aggtattatc
    43621 atgaaagtaa gaccatcagt aaaaccaatg tgcgaacatt gtaaagtaat tcgtcgtaaa
    43681 ggacgcgtta tggtgatttg cccagcaaat ccaaaacata aacaacgtca aggataattg
    43741 gaggtgctat aaatatggct cgtattgcag gagtagatat tcctcgtgat aaacgtgtag
    43801 tagtttcact tacttatatc tatggtattg gtaacactac tgctaaaaag atcttagctg
    43861 atgctggtgt atctgaagat gttcgcgttc gtgaattaac gaatgaacaa acagatgcta
    43921 tccgtgcaga agtagataaa ttaaaagttg aaggggatct tcgtcgtgaa gtgaacttga
    43981 acatcaaacg tttgatggaa atcggttctt accgtggaat ccgtcatcgc cgtggattgc
    44041 ctgttcgtgg acaaaacacg aaaaacaatg cacgtactcg taaaggccca gctcgcgcta
    44101 tcgctggcaa gaaaaaataa ttcttaagtg aaggaggtta aaacttcatg gcagcaaaaa
    44161 aagtgaatcg taaacgccgt gtgaagaaga atatagaagc aggtattgca catatccatt
    44221 ctacattcaa taacactatc atcatgatca ctgatactca cggaaatgca ttagcgtggt
    44281 catcagctgg ttcattaggt ttcaaaggaa gcaaaaaatc aactcctttt gccgctcaaa
    44341 tggcagcaga aactgctaca aaagcagcaa tggaacacgg attaaagact gttgaagtaa
    44401 cagttaaagg acctggttct ggacgtgaag cagcaattcg ttcattacaa gctacaggtt
    44461 tagaagtgac tgcaattcgt gacgtgactc cagttcctca taatggtgcc cgccctccaa
    44521 aacgccgtcg tgtttaatga gtgccgctca ttttgagttt tatcagtaac gtcattgaac
    44581 aagacacttt tcgttttgaa aggggtaaag ataagaatga ttgagttcga aaaaccaaga
    44641 atcgcaaaaa ttgatgaaga aaaagattat ggcaagttca tcgttgaacc tcttgaaaga
    44701 gggtatggga ctactttagg gaattcccta cgtcgtattt tattatcttc tttgccaggt
    44761 gctgccatca ctaatattca aatcgatggt gtactgcatg aattctctac catcaaaggt
    44821 gttagagaag acgtcactca aatcatcttg aacattaaag gcttagcgct gaaaatgtat
    44881 ggccaagaag aaaaaaccct tgaaatcgat attaccggac ctgctacagt aactgctggc
    44941 gatattatcg ttgatagtga tgtagaaatt cttaacaaag atatgtacat ctgtagtgtc
    45001 tctgaaggag ctacgttcca tgctcgctta acagtgaaac ctggacgtgg ttatgttcaa
    45061 gcagatgaaa ataaaaaaga agatatgcca attggcgttc ttccagtcga ttcaatctac
    45121 acacctgttc gtcgtgtgaa ctatcaagtt gagaacacac gtgttggaca ccgtgaagat
    45181 tttgataaat tgacgatgga gatttggaca gatggttcaa ttgaaccgtt ggaagcaatg
    45241 agtttgtctg cgaaaatcat gactgaacat ttggatattt ttgtgaactt aactgatgaa
    45301 gcaaaaaatg ctgaaatcat ggtcgaaaaa gaagaaacac aaaaagaaaa aatgttggaa
    45361 atgacgatcg aagagttaga cttgtctgtt cgctcttaca attgtttgaa acgtgcagga
    45421 atcaatactg tacaagaact tacaaataaa tctgagcctg aaatgatcaa agtccgtaac
    45481 ttaggacgta aatcattaga agaagttaaa gcaaaattgc acgacttagg tttaggttta
    45541 cgtaaagaag attaaaacct tttacgaagg agggaaacca acgtgagtta tcgtaaacta
    45601 ggacgcacat ctagccaacg taaagcgatg ttgcgtgatt taacaactga tttattaatc
    45661 aacgaacgta ttgtgactac tgaagctcgt gcgaaagaag ttcgctcaac tgcagaaaaa
    45721 atgatcactt taggtaaacg cggagatttg catgcacgtc gtcaagctgc ggctttcgta
    45781 cgtaatgaag ttgccagcgt gcgtgaagaa aatgaggaca tcgtcattga atcagcttta
    45841 caaaaactgt tcaacgatat tgcacctcgt tacgcagaac gtcaaggcgg atacacacgc
    45901 attttgaaga cagaaccaag acgcggtgat ggtgcaccaa tggttgtctt agaacttgtc
    45961 taaaatcaca ctaataacat cactttatag atgattcttt tagagtgtta tgatgttgga
    46021 agatattttt ccgagtctag ctcagcgctg ctcctcaagc gaatatcgct tggggagtaa
    46081 gcactcatca taaagtgttt ttttatacct tcaattacct gtcatgacag atatgtttga
    46141 aggcataaaa aaacatttta agcgagaaat aattgaaaat tttgtctttt tttgatagtg
    46201 ttagtaggaa ctttaggatg aagaaggagt aatcatggag ccaattattg aattagaaaa
    46261 gataaattat aaataccagc cagatgatct tcgccccgca ttgaaagatg tctcctttac
    46321 aattgataaa ggtgagtgga tcgctattat tggacacaat ggttcaggaa aatcgacact
    46381 tgccaaaacg atcaatggat tgcttctgcc agaatcaggg atcgtgaaag tgggaaatca
    46441 aatattggat gaagaaaata tttggacgat ccgacagatg gttggaatga tttttcaaaa
    46501 tccagacaat cagtttgttg gttcgacagt agaagatgac gttgcttttg gtcttgaaaa
    46561 tcaagggatt cccagagaag aaatgctagt gcgtgtgaaa gatgcacttg agaaagttag
    46621 aatggctgag tttgcttcac gcgagcctgc tcgtttatca ggagggcaaa aacaacgtgt
    46681 tgccattgcc ggcgtggttg ccttacgacc tgatatcatt attttagatg aagcaaccag
    46741 tatgctagat ccagaaggtc gtgaagaagt gatctctacg atcaagaaga tcaaagaaga
    46801 aagtcaattg accgttatat ctatcactca tgatattgat gaagcagcta atgccaatcg
    46861 gatactagtg atgagacaag gcgaacttgt ccgtgaaggt acaccaaaag aaattttttc
    46921 tgctggtcct gaactgatcg acttaggtct agatctacca tttcctgaaa aactgaagag
    46981 cgcactgaaa gaacgtgggg ttgatgtgcc cagtgaatat atgacagaag aaaggatggt
    47041 ggattggtta tggacatccg ttttgaacaa gtagacttca cttatcagcc gaatacacca
    47101 tttgaacaaa gagccttatt tgacatcaat atgacgatca aagaaaacag ttatactgca
    47161 ttagtagggc ataccggaag cgggaaatca accttacttc agcatttgaa tgcgcttgtt
    47221 aagccaacaa gcggtacagt ccatattgga gaacgagata ttcagccgga tacggataat
    47281 aagaatttaa agcccatccg aaaaaaagtt ggcatcgtct ttcagtttcc agaagcacag
    47341 ctattcgaag aaacggtagc aaaagacatt gctttcggtc ctaaaaactt tggtgtcagc
    47401 gaagaagaag cactagtcct agcaaaagaa acattagaac aagttgggct ggatgaaagc
    47461 tatttggaac gttcgccatt tgaactttca ggagggcaaa tgcgtagagt agcaatcgct
    47521 ggtgtgcttg ccatgaggcc ggaagtactt gtattggatg aaccaacggc aggacttgat
    47581 ccccagggca gaaaagaaat gatggagatg ttttggcgtc ttcataagga acagcagatc
    47641 actattgtat tagttacgca tttaatggat gatgtagcca attttgcaga ttatgtctat
    47701 gtgttggaaa agggacgaat cgttaatagc ggggagccgc aagaggtctt tcaaaacatt
    47761 gaatggctaa aagaaaaaca actaggcgta cctactgcca ccgagtttgc agaagaatta
    47821 atggctaaag ggatgaactt tgctaccttg cctttgacag ctgaagaatt agcagacgct
    47881 atcgtccatt atgctggagg aaatgcccat gatgaataaa ttgatatttg gtcgttatat
    47941 gcctggagat tccttgatcc atcgattgga tccccgagct aaattattag ccagttttta
    48001 ttttatcgga atcatttttt tagcaaataa ttgggaaacg taccttttgt tggcattttt
    48061 cacattactt tctgtcttct tgtcaaaagt agatttgaaa ttttttatcc gaggcattcg
    48121 cccattgatc tggctaatcc tcttcactgt agctttgcag gtcttgttta caagtggcgg
    48181 agaaacttat tggagttggg gtgttttcca tatcactgaa tttggtgtga tgaacggcct
    48241 ctttattttc tgtcgattcg tgttgatcat ttttatgtcg actctactca cgcttactac
    48301 accgcctttg gaattatcgg atgcgattga gtacttgctt cgtccattga aagccgtacg
    48361 gttcccagtc cacgaaattt cattgatgct gtcgattgct cttcgttttg tgcctacatt
    48421 gatggacgaa acagaaaaga tcatgaacgc tcagcgcgct cgcggtgttg attttggtga
    48481 aggaaaccta gttcagaaaa tgaaagcagt cattcctttg ctgattcctt tatttgtcag
    48541 cagcttcaac cgtgcggaag atcttgcgac tgctatggaa gcaagaggct acaaaggtgg
    48601 ggaaggaaga acgaaatatc gtgtattgca ttggcataat agagacacga tggttatcat
    48661 tgcttttgta ttattaactg tgctactgat ctttttaaga ggataaacgt tcagtgggcc
    48721 gctatctatt cttttcttgc tgatctgttt gcaagaaagg atgcaagcag tgtatgacaa
    48781 gaaatattag ggtctgtggc agactaaggt cacaggcctc tttcttttat ctgaaaagaa
    48841 agaacgaaaa aattttatag aaaaatcatt attccagata accttttagg aacaaaggag
    48901 agaaaaacat ggtacgttac aaagcaatca ttgcgtacga cggaacaaat tttaatggat
    48961 tccaaaaaca gccaaatggg cgtactgttc aagaagaagt agaaaaaaca ttacaaaaaa
    49021 tggcaaatgg aaaagaaatc acggtctttg gttcgggaag gacagatgcc ggagtacatg
    49081 cgatcgggca agtaatccat tttgattatc cagaggagcg tccgttagaa cgaatgcgtt
    49141 tcgcgctaga tacccagtca ccagaggata ttgctgtaag acaagtagaa attgtttcag
    49201 aagacttcca cgcaagatat ttggtcaaag aaaagacgta tcaatttcga gtggatatag
    49261 ggaaaccacg cagtcctttt cgacgccatt atgcaagtta ttttccttac ccacttgatt
    49321 tggaaaaaat tcagcgggcg cttcctgatt tattagggac tcacgatttc acctcttttt
    49381 gtgcatcagg aagctcgata gaggataaaa tacgtacgat ctacgaggct aagatggagg
    49441 taaatgaaac aaaagacgaa ttgttgttta catttagggg aaatggcttc ttgtataaga
    49501 tgatacggat cttagtagga acgcttttga aaattggcaa tggccgattg cctgaagata
    49561 gtatcccaga tattattgcg aaaaaagatc gtaatgcagc aggacctaca gcacaccctg
    49621 aaggacttta tttgtatgaa gtgaaatatg aataagaggt tatgatagaa gtggtcagct
    49681 tcaagaaata agaaggtatt tacgaaaatt acttctcaaa attttgcaaa atttcggctt
    49741 attttcgaag aagctacttc tggaacaccg tttaagaaag aggtcgtgag cctgtcattt
    49801 aactctgagt cacaaagagc aatttcaaaa aacagcttct catctttgat gaatatcgtg
    49861 acttgtggac gaggcgttga taagtgaatc atctttttgt tacctatttt ttctgtaacc
    49921 aaaaaacgat ggaacgttgt tttgattgcc cttggtgcgg acagtctgaa caggttccat
    49981 cgtttcttta ttttctacgt cttcttctgt gtgtgtttcg tggttgttct tctattgctg
    50041 gatcaatcgt gccataaaag gggcgattgc ggtcaaggta ccagacataa agaataaaca
    50101 atgcaataca taggacaaaa aggattgcac ctatcgtaaa tccttcaggc aagtaactga
    50161 aagtgacagt atgtttacct gctggaactt ttatcatcaa gaatgcgtct ttgaaattgc
    50221 tgaccttgac tggtttccca tcaattttag ctttccatcc tttgtcataa ggaatagttg
    50281 tcaccaacat ggaatcttca gcggtattta cagtcccaga agcttttctg ccagtggctt
    50341 ccatttcgac acctttttct ttgatctgat tcattgcggc ttgataggct acaacatcta
    50401 gaccaacgac tttaggctcc atgaaactta tttctttcgt cccataaaaa cttgcagtaa
    50461 atgtcactgt tgtctcttga ggataatagc caagatcata gtattgacca gaaatgttga
    50521 tttgcgtttt tcgcgatgta ccattgacag tgatcgtcgc actagaactt tctaattgcg
    50581 caaaattggt tgggaacaaa cttaagtaag cttgtgtatt tgcaggcaca tggacttccc
    50641 aagtgagctc ttttggctgg ttatctgctg tttctgagta agtgacgcca gtcgttgtct
    50701 ttgtgatcgt cgtattcaac tgattcttca aagtaggtgt atagaatgta aaatactgtt
    50761 catttagacc agacaatgta ttgatcaagt ttgtctgact ggtcaaatta tctgtcactg
    50821 gctgctcaac atcattaacg gacaacggtg cagtaaatgc tagtggcaat gcattgacat
    50881 tctgatacag tgtatagtcg ccgctttgac cagcttggcg gaagccatat ttactgaacg
    50941 tgctttcgtt tttagaaatg ttatatttga ttcctgtaaa cccatccatc agcaaagtat
    51001 tattgttata acggatattc aaatttgtcc ctcttgaacg gaaacctaat ttatccaggt
    51061 aagaggaaga attacgattt cttatagaag aaaacaaact gataccactg taaccatagt
    51121 tgatcgaatc gtttgcagat actggatcca gattttccaa gcggtaaaac gagtcggaat
    51181 ctttttttgt ttcatttaca agagctttca agtcaggata aggatcagta tataaactgc
    51241 gggaagcata attccaatca tcaagaatgc catggatcat actgttcgta ttgaccagtg
    51301 cttcagcaga catgatcaat aataacaata tactcagatg attgaatgaa agttttttat
    51361 gctgataaaa tcccacagca aaagcataaa tccctaagaa aaccactgtc aatacaaagg
    51421 aagtcatcgt cacataggtg tagcttcctt caggtttgat gccccatgcc accgcaaaga
    51481 gagcagctac gaccaaaatg attcctaaca acagcccacc atcgtcttgt tctatctttt
    51541 cccatccttt tcctgcaagc aggagcacta agaaagagaa cagataggca taacggaata
    51601 aaaacatatt cggtgcatgc ataccatgcc agaacaaatt caatggaaca agataaaaac
    51661 ttgcgataag tatggcgaaa agactgccgt acaaaaattt atttttcaac ggtactttcc
    51721 gactggcaaa ataaaacaga cagaggacta atggtagcag acctgcgtaa acgaacggaa
    51781 tcgatccgta ttttgtcgtg tcataaacac caatcatatt tttcatgatt agatccagat
    51841 aagaagtcgc ttctgttttc aacgtagtga tctgactcag tgcctcgcca tttgaccgaa
    51901 gatccagcac tgctggcaat acaatgatca ttgaagcgcc gcctgccagt aaagaagtga
    51961 taccataagg aacaatcgtt tttttatatt ctgaccagtt tgtcaataga cgggcgataa
    52021 aatataagaa agaaaatacg ccaatcataa aacccatata aaaactggat aaaaacaaga
    52081 gtaaataact gataaataaa agtttcggcc gtttaagatc cataacacga tgaatcccca
    52141 aaatcactaa tggaagataa acaaatgcat ccagccacat gatgatctcc gaatgtgcag
    52201 tgataaatga gatcaatgcg taactgacgc taagtgcaac atgcccccag cgaggaatct
    52261 tgaacgtacg tgcaagaaac caaaaagcca atccggcaca gccgacctta agcaaagtca
    52321 gaacatacag tgcatctggc atcatctggt ttggaaaaaa gaacaccagt ggcgtgaaga
    52381 tcccgcctag atagtaagaa attaaagata aataattcaa tcctagagaa gcattccatg
    52441 tataaaaaat actttgcttt ccaagaagaa catttcggaa gctggcatga aaattagaaa
    52501 actgtgaaaa ggcatcactt gccaaaatac ttctgctgct tccaggatag attccgatac
    52561 ttagataaac aagtgctaaa atcaaaaacg gaatcaggaa actagctgct gcgtagcgtc
    52621 cgttttctct aaagaatgac tttaaatttt ttttcatatt tattttccac caaatttcta
    52681 tgaagttgta ttcagtttat catatccttg tttttctctg cttaaaaaga gtctagtttt
    52741 cacaaaaaaa taaaatttag aataaataac ttcataattt gttcgtataa caaaaataaa
    52801 cgcaaaaaaa gggtaggaat caaaagtccc acccttaaaa atttttatta aataaaaaac
    52861 cgttcactat ctgaacggtc caagtatcat tcaattaaac gcgttcaact tttcctgatt
    52921 tcaaagcacg agttgacacc caaacttttt taggttttcc gtcgaccata acgcgaactt
    52981 tttgtaagtt aggtttaaca gtacgttttg ttgagttcat agcgtgtgaa cggttgtttc
    53041 cactttttgt cttgcgacct gtaaagtaac aaacttttgc catggtaatt tcctcctttg
    53101 ccttgatttg gagcaataga ataattcagc tcataccaga ctaacatatc atatagaatg
    53161 ggaatttgca agtacatttt catagataca attgacaatt gagaagaata attgtaaatt
    53221 aaacaaggtt atacctgaaa ttttgcaagg tttttgagta ctttgggtaa ctgcctttta
    53281 tttcaagttg cgctatgata aaatatgata gaagaaaaat gggagttttt tacccgttaa
    53341 ggaggctcat tcatggctgt aaaaattcaa acgtcagctg gaaccattga aattaccaat
    53401 gatgtaattg caacagttgt tggtggcgcc gcgacagatg tgttcggtgt tgtaggaatg
    53461 gccagcaaaa atcaaattaa agataatatt actgagattt tgcgtaaaga aaattactca
    53521 agaggagtag ttgtccgcca agaagataat ggtattgctg tagatgttta tacgattatc
    53581 agctatggta cgaaaatctc tgaagtttcc cgcaacgtcc aagaaaaagt gaaatacaat
    53641 ctagaggcat tattaggcgt aactgccaat tcagttaatg tctttgtaca aggtgttcgt
    53701 gtactgccag actaggcagg agactggctg gtaactcagc agtcgatctg aaggaggatt
    53761 atctaggtga gtgtaacaga aataagtgca agccagttcc aggaaatggt ccaggcaggt
    53821 gcgaatcgtc tgcaagtaaa tgcagaatac gtcaattcat taaatgtatt ccctgtgcca
    53881 gatggcgata cgggaacaaa tatgaatcta tctatgacta gtggagctaa ggcagtagta
    53941 gattcaacct cagaaaaagt aggagaatta gcagcaatgc tttcaaaagg attgctgatg
    54001 ggtgcgcgcg gaaattccgg cgttattttg tctcaattgt ttcgtggatt ttctaagcaa
    54061 attccagatg ttgtctcatt aaatgcttct gatcttgctg cagccttcac tcatggagtt
    54121 gaaactgcgt ataaagcagt aatgaaacca gtagaaggaa cgattttgac agtagctaga
    54181 gaagcagcga aagctggaga aaagaaagca aaaagtactg atgatgtcgt tgaagtaatg
    54241 acagctgttg taaaaggagc aaagcgtgct ttagctaaaa ctccagactt gcttccagtc
    54301 ctaaaagaag tcggtgtcgt agacagtgga gggcaaggac tgctgtttgt ttatgagggc
    54361 tttttaagtg cattgaatgg agaattccaa gcggatgaaa catatgaacc ttctccagca
    54421 gaaatggatg atatggtcaa tgcagaacat catcgcagtg tccaaggtca aatggcgaca
    54481 gaagatatcc attttggtta ctgtacagaa atcatggtaa aaatcggaga aggacctaca
    54541 gtcgatagta cattcgatta cgaagaattc cgtaactatt tagatggtat aggagattct
    54601 ttacttgtgg tcaatgatga cgagatcatc aaagtccacg tgcatacaga aaacccagga
    54661 gaagtcttga attatggaca aaaattcggt tcattagtca aaatcaaagt cgacaacatg
    54721 cgcttgcagc atgagacgat tttggaacac gatgaagaag tgaacgagtt tgcgaaaaaa
    54781 gaaataccac gtatcccgta tggtatcgta gcgatcgctg ctggtaaagg cgtccaagag
    54841 ctgtttgaaa gtttaggcgc taattatgtt atcagtggtg gacaaacaat gaatccaagt
    54901 acggaagaca ttgttaaagc gattcaagaa gtaaacgcag ataaagtgat tgtcttgcca
    54961 aacaataaga acatcttcat ggcagctgat caagcagcag aagtagcaga tatcccagta
    55021 gcagttgttc cttcaagaac gatttcccaa ggattgacag ctatgctttc attcaatgat
    55081 caagcttctt tagaagaaaa caaagaaacg atgacagaaa tgttgtctag cgttgtgagc
    55141 ggtcaagtca ctcacgcgat cagagatacc tcaattgacg gtgtagagat caaagaagga
    55201 gactttttgg gcatgatcga tggaaaaatc ctgatctcta acccagatat cacagcaaca
    55261 gcgttaagta cactagaaca aatgatcaat gaggacacag agatcgtaac gatcttggca
    55321 ggtgatgaag gaacagttga acaagcaaat gaatttgctg agaaactaac agaaaaacat
    55381 cctgatttgg aaatcgagat ccaccaagga gatcagcctg tctatcctta tctattttct
    55441 gctgaataat ttctgtgtca gaatatcttt ctaacacagt attcattcat aaaaggcctt
    55501 cggttagtga tcaggtatga tcgctgacca agtccttttt ttgttaaagg agggaggaaa
    55561 aatttatgcg ttctttagat gatccaatca ctatgctggc aggagtcgga gaaaaaagag
    55621 cagctagtct tgccagcttg ggcatccaaa cgattgaaga cttactgact tattatcctt
    55681 ttcgctacga agatattcag gaaagaaatc taaacgagat ccaggatcaa gaaaaggtta
    55741 ctttgaaagg aatcgtagtc tcgcctcctg tgatgaatcg atttggttat aaaaaaagcc
    55801 gattgcaatt tcgtatgatg caagaacatg atgtgttcaa cgtttctttt tttaatcaac
    55861 cttatctaaa agaaaaagtc attttatcgg aggaaatcgc cgtatacggt aaatgggatg
    55921 caaagcgtaa agccttgaac gggatgaaga ttttaggttc tcaaacaatg gatgactttt
    55981 cgccgatata tcacgtcaac aaatcaattc gtcaaacgac attagttgat ctaatcaaaa
    56041 aagggtttca agaatacggc acattgattg aagaaaatct gccaaacaac cttgtggaga
    56101 aatatcgact gcttgaccga gcttctgctg taagaagtat gcattttcca aaagaccacg
    56161 aagaaaacca tcaagccaaa cgacgtgtcg tttttgaaga gttcttttta tttcaaatgc
    56221 gtcttcaagg attgaaaaaa gcagaaaaag cagaaacgaa tggtttggag atcctttatg
    56281 atgtccaaaa attgaaacaa tttactcaaa agctaccttt tgaactgaca aatgcacaaa
    56341 aacgtgtaac gaatgaaatc tgtcgggatc ttcgcagtcc gcagcatatg cagcgacttt
    56401 tgcagggaga tgtaggtagc ggaaaaacag tggttgccgc gattgcgtta tacgctaccg
    56461 ttacagcagg tttccaaggt gcgttgatgg tgcctacaga aatcttggca caacaacata
    56521 tggaaagctt gcaacagctg tttgatccca atgaagtaac catcgcattg attacggggt
    56581 caacgaaagc aaaagaacga cgtgagctcc ttgaaaaact agagcaaggg gaaattaacg
    56641 tcgtgatcgg cacacatgca ttgatccaag atggagtcga atttcagaat ttaggtctag
    56701 ttattacgga tgagcagcac cgttttggcg tgaaccagcg gaaagtactt cgtgaaaaag
    56761 gctggcgacc agatgtctta tttatgacag cgactccgat tcctagaaca ttagctatta
    56821 cagcatatgg tgagatggat gtatctatca ttgatgaact tccagctgga cgtatcccga
    56881 tcgaaacacg ctgggtaaga acacctcaat tggacagtgt actggattgg acgaaaaaag
    56941 aactggcaag aggacatcaa atgtatgtca tctgtccgct gattgaagaa tcagaagcat
    57001 tagatgtaaa aaatgcagtg gaaatctatg aaaaacttcg tgaactattt gcaccaaaat
    57061 atgaagttgg cttgttacat ggtaaaatga agaatcagga aaaagaagta atcatggaag
    57121 ccttcaaaga caaccagatg cagatattag tttcgactac tgtaattgaa gtaggggtaa
    57181 acgtgccgaa cgcgaccgtc atgctgatca tggatgcgga tcgatttgga ttggcacagc
    57241 tgcaccaact tcgtggacgt gttggacgcg gaagtgatgc ttcctactgt atcttagttg
    57301 ctaatcctaa aaatgaacta ggtgtggaac ggatgaaaat catgacagag accaccaatg
    57361 gttttgtact aagcgaaaaa gatctggaat tacgtggtcc tggtgaagta tttggcttcc
    57421 gtcaatctgg tctgcctcaa tttgcgattg ctgacttggt gacggatgga aatgttttgg
    57481 aggtagccag agaagaggct gcagcccttt ggcaaataaa ggattggcag atgcttcctg
    57541 agtatcagcc tttagcgcaa agcctccaaa tagaaaatca ggataatcgt tatttcgatt
    57601 agcagactgt gctatacttt atactgatga cggaaaaagg agtggaaaca atgaaaattg
    57661 ccgtagatgc aatgggcgga gatcacgcac ctcaagcaat tgtagaaggc gtggctttag
    57721 cgcagcaaga ttttccagaa gtagaattct tactttacgg aaaagaagca gaaatcaaga
    57781 aatacttaac aaatgaaaaa aacatcacga ttatccatac agacgaaaaa atcaatagtg
    57841 atgatgagcc agtaaaagca attcgacgaa aaaagactgc atcaatggtc cttgctgcac
    57901 aagcagtgaa aaacggtgaa gcagatgctg tattttcagc agggaataca ggcgcgctac
    57961 tagcagcagg gttgttcatc gtaggacgta tcaaaaatat cgaacgccct ggcttgatgt
    58021 ctaccttgcc agtagtaggg aaagaaggtg ccggtttcga tatgctggat cttggcgcta
    58081 acgcagaaaa caaaccagaa catttgttgc aatacggtat tttaggttct ttttatgcac
    58141 gtaaagtccg aggtatcgga cgtcctcgtg tcgcactctt aaacaacgga acagaagcaa
    58201 caaaaggtag tgaagtgacg aaaaaagcct atgaactcct tcagaatgaa acaagcttga
    58261 attttattgg aaacgtagaa gctcgtgagc tactcaatgg tgtggctgat gtagtggtca
    58321 cagatggatt tacaggcaac gctgttttga aatctattga aggaacagca atgaatatga
    58381 tgaatctatt aaaatctgct attctaaatg aagggatcaa aggaaaaatg ggcgctatgc
    58441 ttttaaaaga cggcttacgt tctttgaaag cagaaatgga ttattccaaa catggcggtg
    58501 ccgttttgtt tggcttgaaa gcaccagtca ttaaaactca tggagcaaca ggccccgatg
    58561 ctgttcgcta tacgatccgc caaatccaca caatgcttga gacagatgta gttggacaat
    58621 tagtcgaaca atttgaaaaa agcgaagaat agtatttgga tatctgaagc gatccgttcc
    58681 attgaaaaaa aggtggacat tcctgaaaaa tgccagtaaa attagccatg gtgtaggtaa
    58741 ttgacaagtg tatgattctt ggaggtgaaa aagttgactc gcgaagaagt atttaacaaa
    58801 gtagcgaaaa ttatttcaaa tcattttgag atagataccg ataaagtgac ggatgaattg
    58861 aacatcaaag atgatttaaa agctgattca attagtatta tggaattcgt tttagagctt
    58921 gaagatgaat tcggtacgga aatttcagat gaagacgctg aacaaattga aacagtcggt
    58981 ggcgcagtag attatatcag cagccatctt aaataatttc aaataaaagc aaagaaggat
    59041 aaaaagctgc atgcagcttt ttatccttct ttttttaatc tttttgacac gtaaaagtca
    59101 tttttctgat aattctggcg ataaacagaa attatgttgc aaagtaaagc ggttttctat
    59161 ataattatta ataattcatt acacaaagat aagaataacc tttgttataa aacgatttat
    59221 tctgtgtaat gtcctttttt attaagaaaa acttccattt aggaagcaga gaggggtatt
    59281 cgattgtccg ataaccaatt attagaagtt cagaacctac atacaggatt ccgactcaaa
    59341 gatgactatt acgatgcagt agatgacgtt tcatttactt tagacaaaaa cgagatttta
    59401 gcaatcgttg gggaatctgg gtgcgggaaa agtaccttgg ctactacgat tatgggatta
    59461 cttgatccta ataacacaaa aattacaggt gagattttat ataacgatct gaatttaatc
    59521 gacctgaacg aaacgctcta taataaaatc cgcggaaatg atatcggaat gattttccaa
    59581 gatccgttgt ctgcattaaa tcctctcatg agaatcgaag accagatcaa agaaggactt
    59641 tcctatcaca caaagatgaa tgcagaacag cgtcaagctc gtgcactaga attgctagaa
    59701 caagtaggga ttcctaatcc tgcgagagtt ggacgccaat atccccatga actatcaggc
    59761 ggtatgagac aacgtgtcat catcgcaatc gcaatcgcct gcaaacctcc aatcgtcatt
    59821 gcagatgaac cgacgacagc cctagatgta accatccaag cacagattct tgatttactg
    59881 aaagaccttc aggaagaaac aaaaacaggg atcatcttga tcactcatga cttaggagtc
    59941 gtagcagaaa tggctgatcg agtggcagtg atgtatggcg gacagttcgt tgaagtagca
    60001 ggtgtaaaag aactgtttga tcatcctaag catccttata cacgctcttt actgaactct
    60061 ataccacaag aaggaaatca tgatgcagaa ctccatgtga tcgaaggtgt cgttccttct
    60121 ctgaaaaaca tgcctcgtaa aggttgtcgg tttgcaccac gtattccatg gataccagca
    60181 agcgatcatg aagaagagcc tatccttcat gaagtcgcac cgaaccactt ggtacgttgc
    60241 tcctgctata agcatttcca ctttagagac gaaaaaggag aggtgtagat gacagaatta
    60301 atcacaatca aagacctgaa agttcattac cctattcgca gtggattctt caatcgagta
    60361 acggatcatg tatatgctgt agatggtgtg gattttatta tcgaaaaagg aaagacatat
    60421 ggtttagtgg gagagtctgg ctctggaaaa tctactacgg gaaaagccgt tgtgggatta
    60481 gaaaaggtaa cagccggaca aatcatgtat gaaggaaaag atgtaacgaa gcgaagcaac
    60541 cgcaaaaaaa tgggttataa caaggatgtg cagatgatct tccaagattc aatgtccagt
    60601 ttgaatccta aaaagcgagt gttggatatc attgctgaac ccatccgaaa ttttgaacgg
    60661 ttaagcgatc aagaagaaaa gaaaaaggta aaaggactgc tagatatcgt tgggatgccg
    60721 gaagatgcgc tatataaata tcctcatgaa ttttcaggcg gacaacgtca acgtctagga
    60781 gtagcccgtg ctgttgctac caatccaaaa ctgatcgtag ccgatgaacc tgtatctgct
    60841 ctggatctat ctgttcaagc gcaagtattg aatttcatga aacgaatcca gcaagaatac
    60901 ggcctcagct atttattcat ttcacatgat ttaggtgtag taaaacacat gtgcgacaat
    60961 atcgcaatta tgtacaaagg tcgatttgta gaaatcggta caagagaaga catttataat
    61021 gacccgcgac atatctatac gaaacgtctg ctttcagcta ttccgcaaat cgatgtagaa
    61081 aatagggaaa gccacaaaga aaatcgacga agagtagaac aagagtatat ccaaaaccaa
    61141 aaagaatact atgatgcgac tggtcgagtc tacgatttgc gtacgatcac aactacacac
    61201 aaagtggcgt tgaaagatgg aggtgcaagc taatgtggaa aacgattctg cgacgtgttt
    61261 tattgatgat cccgcaagtt attattttaa gtgttctgat cttcttatta gcccaagcga
    61321 tgccggggga tccatttacc ggtttgatca atccaaatca ggatccggca gtgatcgaac
    61381 agatgcgaca agcagctggc ttgaatgacc catggtatgt ccagtacttc cgttggatcg
    61441 gaaatgcttt gcaaggcgat tttggtcaaa gtttcttata caaacgctct gttgctgact
    61501 tgatcggcga acggatcatc aacactttat atctatcgat cttgacagtt gtccttactt
    61561 atttgattgc tgtgcctctg gggatgcttg ctggccggta tcaaaattca atcttggata
    61621 agattgtcgt aatctacaac ttctttagtt ttgctgttcc tttatttatc ttcggcttga
    61681 tcatgctatt tgtttttggt tatcgtttag gctggttccc aacaagtgga tcacaaacac
    61741 taggtttgca aggtggattt atcactcaat ggatagaccg tttgaaatat attctgttac
    61801 catcaattac ccaagcattt ttggcgactg ccgtcacaat ccaatatctg cgaagtgaag
    61861 taatcgattc gaaatcgctc gattttgtca gaacagcccg ttccaaaggg gtaccgacga
    61921 ataaagtatt cagtcgacat attttccgaa atgcagcgtt gccgatggct tctcaaatgg
    61981 ggtatgaaat cacttcgttg attgctggtt ctgtagttat cgaaaagatt tttggttatc
    62041 cgggagtcgg aaaactattt attgattcca tcggccaacg ggactatacc gtgatcacat
    62101 ccttagtatt gattttagga atcgcgacgc tagtggggac attactttca gatatcatca
    62161 tgagtatcgt tgacccgcgt attcggattc aataaaacca atcagaaagg agaatggatc
    62221 gatgagtgaa aaaaacaata cagcagttca agaaagtatt cctcctatgg ggatacgaat
    62281 gattgctcga gaatttaaaa aagataaaat tgctattttt tcattaggtt tgctagtggt
    62341 tttattatta gtgatcttta tcggtgcgat gctgaccgat caagacaaag tgatgtatgt
    62401 tagtatcttc gacaaatacg ctgcaccagg aacagtttcg acacaaggac aaaagttcat
    62461 tctgggagca gatgaaggcg gacgtgatgt attaggacaa ttgatcatag gtgctagaaa
    62521 ctctgttacg atcggatttg cgatcacgat ccttacttcg atcatcgggg ttggattagg
    62581 gatcatctct ggctactacg gagggatcat tgacaacatc ttgatgcgga tcgttgattt
    62641 tatcatgatt ctaccgatca tgctgatcat tatcgtcttc gtatcgatta tttccagata
    62701 caatgtctgg tcctttatat tcatcatgag tgcattttat tgggtagcta aagcccgatt
    62761 attccgaagc aagacattat ctgaagcaag aagagattat gtcagtgcct caaaaacaat
    62821 gggaaccaat gattttaaaa tcatgttccg cgaaatcatg ccgaatctaa gttcattaat
    62881 cattactaat ttgacgatga actttgcggc aaacatcggt atcgagacaa ctttgacttt
    62941 cttaggtttc ggcttgccgg caaatgtacc tagtttaggt acattgatcg gttatgcaag
    63001 taacggagaa gtcttagtga atcggcaatg gatctggtta cccgcatcaa tccttatttt
    63061 agttttgatg ttgagtatca attatgttgg acaagcattc aagcgttctg cagatgcgcg
    63121 ccaacggtta ggctagtata gaagcgaagg gggaaatagg aatgaagaaa acgatttttg
    63181 gatttgcagc gctgatgtct gctgtcgttc ttgcagcatg cgggggcgga ggtacagata
    63241 cctctggaaa caactctgga ggcaacggca ataacaaaga ggaattaact tttccaattg
    63301 caacaaaaaa taatgatgat gcaatcgaag acggcgaatt agaagctgcg gtcgcaacgg
    63361 acagtcagtt taaaggattg ttccagtggg agttttacca agattcatat gatgcagctt
    63421 ttatggctcc ttctcatgaa ccgctatttg caaacgatga cgatttcaga atcacagacg
    63481 acggagctgc aacgcttgat ctagatgaag atacgaaaaa agcgacaatc aaagtaaaag
    63541 acaacgtcaa atggtcagat ggtgaagatg taacggcgga cgatgtgatt ttcccttacg
    63601 aaatcattgg gaataaagat tacactggta tccgttatga cgacactttc cgtaacatcg
    63661 taggtatgga agaatatcat gatggaagtg ccgacacaat ctccggaatc aaaaaaatag
    63721 acgacaaaac agttgaaatc gaatataaag aagtaaaccc aagcatgctt caatcgggtg
    63781 gtggtatctg gtcatatgca gcaccaaaac atacgttaga aggtgtagca atcaaagata
    63841 tggaatcaag cgatcaagta cgtaaaaatc cagtgacttt tggcccttat tacatgagta
    63901 atatcgttgc aggagaatca gtagaatact tgccaaacga gcactactgg aatggtacgc
    63961 ctaaattgaa aaagatcacg atgaaatctg taccgatggc aagtgcaact gaagcattga
    64021 actctaaatt atatgatatg attttccaaa tgccaacaga tacttacgat acctataaag
    64081 aaattgctgg ctatacaaac ttaggccgtg aacaaacttc ttatacttat ctaggattca
    64141 agttaggtaa atggaatgca gatacaaaga gtgtggaata caatccagat tcaaaaatgg
    64201 ctgataaatc attacgtcaa gcaatgggct atgcattaga taataatgca gtaggtgaac
    64261 gtttctatgc aggtttgaga agcaatgcga cttcattgat tcctccagta ttccagtcat
    64321 accatgatga tgagatgaaa ggattcacac aagatctaga caaagcgaaa aaactattag
    64381 atgatgctgg ctacaaagat gtggatgacg atggtttaag agaagacaaa gatggaaata
    64441 aactaacaat caactttgct tcgatgtccg gtggggaaac agcgcaacca ttggcagatt
    64501 actatatcca acaatggaaa gaaattggtt tggatgtcca atacacaaca ggtcgtctga
    64561 tcgaattcaa ttctttctat gataaattag aaaacgatga tcctgaaatt gatgtttacc
    64621 aagctgcttg gaatacagga actgatccaa atccaagtgg actatgggga ccaaatgctg
    64681 cgttcaacta cactcgttat gaatcagaag aaaatacaaa attgatcaac gatatcagtt
    64741 caagcaaagc atttgatgaa gagtaccaaa aagaagcata tcaaaaatgg caacaatatg
    64801 catttgaaga agcatttgcg attccaacgt tgttccgtaa tgaagtattg ccagtcaacg
    64861 accgtgtcaa agactgggat tggtcttatg atgtaccaaa cccatgggca aatgtttctg
    64921 ttacagcaga ttcacgttca taatcactaa aaatgaccga aaaagggcga tgtccttttt
    64981 cggttttttg atatttttct gtttatttct ctaatattca ggtcaaggcg ctgatttcat
    65041 gacttctcca ataaacggtg ttcaaagtcc agtttctcgg tattaagtca aatttatgca
    65101 aaaatatgga aagccatttt cacaaaattt tttcttcata ctcgaaacta aacgaatttt
    65161 tcacaacttc tcgtcaatca ctaggattat taaagcttta cttacctttt gaccgaacca
    65221 tttcaaattt gacaaaaaac cagtataata aggaagtatc gaaaaaatat ccataaaagg
    65281 aatgtggaaa atggacaacc agctgacaaa agaactaaaa gaaaactata acatcgtttt
    65341 tcacgatcta aatttgcttg aacaagcttt tacccattca tcctatgtga atgagcatcg
    65401 caatctgcaa ttatcggata atgagcgact tgaattttta ggagatgccg ttttagaact
    65461 gatggtttct cagtatttat tccgtttata tcctcatttg ccagaaggaa aattgacaaa
    65521 aacacgagct gcgatcgttc gcgaagacag cttgtcgaaa tttgccaaag aatgtcactt
    65581 tgatcaatat gttttgttgg gcaagggaga agagaattca ggaggacgta cgcgaccagc
    65641 attgctttgc gacctattcg aagctttttt aggcgcgtta tatcttgacc agggattcga
    65701 cacgacccat gcattcatcg aaaaagtgat ttttcctaaa gtcaaagcag gtgctttttc
    65761 acatgagatg gatcataaaa caaaactaca agaagtcttg caaaaatcag gtgatgtatc
    65821 aatcgaatac cgattgatca atgaagaagg tccagctcat gaacgagtat tttggatcga
    65881 agtttatgta gatgatcaat tgattggcac tggacaaggg aaatcgaaaa aattagcaga
    65941 acaagctgcg gcggaaaatg cattggcagc actgtaaaag taagtgaggg aaagctttgt
    66001 atttgaaacg aattgaaata gccggtttta aatcatttgc agacaagaca gtcattgatt
    66061 ttgaaaatag cgtcacagca gtggttggac caaatggcag cggaaaaagc aatattacag
    66121 aggctatccg ctgggtatta ggagaacaat ctgctaaaag tctgcgaggc ggaaaaatgc
    66181 cggatatcat ctttgccggt tccgataccc gtaagcagct gaatattgca gaagtcacag
    66241 tgattttaga caatagtgat cattatctgc cattggagta caatgagatc agtgtaaccc
    66301 gccgttatcg acggactggg gaaagcgagt ttttcatcaa taaacaaagc tgcagattaa
    66361 aagatatcca agaattgttc ttagattctg gattaggaaa agaatcgttc tcaatcattt
    66421 ctcaaggaaa agtagaagcg attttcagta gtaaaccgga agaccgtcgt gggatctttg
    66481 aagaagcagc tggtgtcttg aaatacaagc agcggaaaaa gaaagcagaa cagaagcttt
    66541 ttgaaacaga agacaacctc agccgcgtcc aagacatcat ccacgaattg gaagaacagt
    66601 taactccttt ggccgcccag agtgaggcag caaaggagtt tttacggcta aaagaaacac
    66661 tgactcaaac cgatgtctct ttgatggttg ctgaaatcaa gacagcaaaa aaagattggg
    66721 acaacaaaca agcacagctt gcgaaattca atctagaatt aggcaaacta tctgagtcga
    66781 tccaagaaca agaatccatt ttggcgaagc agcgtaaaga aaatgcgcaa gccgatcgtc
    66841 tgatcgaaaa aaatcagcaa gtattattag atctttcgga aaaactgaag cagacagaag
    66901 gacaaaaaga tgttttgcag gagcggacaa agcatacaca aaaaagctcg caagaatatc
    66961 aaacttcatt agcagaagca caaaaaaagg ttaaacattt tgaaaagctt caagaaagct
    67021 tgatgaaagc agcagcagaa aaagaaacag agatccaaaa agctgaagca aatctcataa
    67081 aaacacagca agaattagaa aaataccaaa aatcaacgaa agaattattg gcagaattaa
    67141 gagatcaata tgttgatttg atgcaagaac aagcagctgt aggaaacgaa ctgaagtatc
    67201 tagaacgtca atatatacaa gaaacagcaa aaagcaagca gacgttagcc aagcaatcgg
    67261 aagtagaagc atcagtagac cgattgatct tacaaaaaga agaattgaca caaaagcagg
    67321 cgcagctaaa atcatcttta actgaaacaa aagagaagtt agaaatgatc caacaaaacg
    67381 ggaaaaagtt ccaagaagca ttagcaaaag aacagcctaa aatgtatcaa ttaatgaatc
    67441 aagtccagca gctacgtgct cgtaagaaaa gccttcaaga aatccaagaa aactattttg
    67501 gtttttacca aggggttcga ttggtcttgc agcataaaca gcagctttcg ggtattgtcg
    67561 gagcagtggc tgaactgatc gatgttcctg cagatttcac gttagctatc gaaacagctt
    67621 taggtggggc agcccagcat gtcatcgttg aaaatgaaaa agatgctcgg caagccatca
    67681 cgtatttgaa acagcaaaga ggaggaagag caacattcct tccactgacg acaatcaaac
    67741 caagacaatt accggctcat atattgacac aagcagcagc tgtagaaggg tttataggga
    67801 ttgccagtga acaagtcagt tatcccgatc aaatccaaac tgtggttcaa aacctgctag
    67861 gaacgatcct tttagccaaa gacttaacta gtgccaatgc aatcgcgcaa acgatccgct
    67921 atcaatatcg agtggtttcc ttagaaggtg atgtgatgaa tgccggagga tccatgacag
    67981 gtggagcgaa taaacgagga aaccaaggca gtttgtttgt acaaaatcaa gaattgaaac
    68041 agttgactag tgaatttgaa gaagcagata aacaactcca agcacaagaa aaaaaagttc
    68101 aggagctgca acaagaaaca gctcgtttag ccgaagaaca agaagttttg cgtacacgag
    68161 gcgaacaatt acgttttgaa gaacaagaag cgacaaatca gctacaaaac atcataaatg
    68221 aacttgaacg ttttgaaaaa gaaaagcaaa tctcaacttt tgagacacgt gaactgcagc
    68281 agtttatcga agattacgaa aagcaaacga acgaattgaa agacaaacaa acagatcttg
    68341 aatcgcaacg acaaaaaatc gacgaagaaa tcaaatcgtt aagtcaagaa agcgaccaga
    68401 tggaagccag aagagcacaa gtacaaagtc aaaaagcaca agaacaagca gatcttgctg
    68461 tcttgaaaga gcagtttaat catctgcaga tccagctccg cggtgcccga gtccaaaaag
    68521 cagaggcaac cgaacgtcaa gaagcgatag aaaagcagtt ggcgacattg acagcagact
    68581 tttctgatca tgaagtcaca gaagaaagtt tggaaaaaca aattaacgaa ttatctgctc
    68641 agcgagaaac attaaaagcc gagttggcaa aagccaaaga gcagcgagat agaaggcaaa
    68701 aggagatcga taagcttgaa gcagtcttgg cagagcgtaa tcgtgagcaa aaagcacgac
    68761 tgtcggaaca atccaaatta gaagtccaaa aagaccgagc tgaaatgatt ttagataatc
    68821 atttgaccta tctgcagtca gaatatcagc tgacatttga gaaagcttcc caagactatc
    68881 aagaaacaac cgatatcgaa gacagtagaa caaaggtttc atccttaaaa gaacagattg
    68941 aaaaactggg accagtaaac ttaaattcaa tcgaacaata cgaacaagtc agtgaaagac
    69001 atacattctt agcaacacag cgagatgatc tgttagcagc gaaaaaccaa ttgtttgaaa
    69061 cgatggatga gatggatgat gaagtgcgga caagattcaa agaagtattt gaagctatcc
    69121 gtcaagaatt caaaattgtc tttccaaata tgtttggcgg cggtaaagct gaattagtac
    69181 tgacggaacc aactgatttg ctgaaaacag gtattgagat tgaagtacaa cctcctggca
    69241 aaaaactgca aagtctaagt ttgctttctg gaggagaacg agcacttaca gccatcgcgt
    69301 tgctcttttc cattatccgt gtctgtcctg ttccgttttg tatcttagat gaggtagaag
    69361 cagcgttaga tgaagccaac gtgaaacgtt ttggtcgtta cttgagcgat ttccaagatg
    69421 acacacaatt tatcgtagtc acacaccgca aaggaacgat ggtcgcagca gatgtactgt
    69481 acggagtgac gatgcaggaa tccggtgtat caaaaatcgt ttctgtacgg atggaagata
    69541 tcaatgaaga ggcgaaaatc aacgaaacga aagtgtagga acgaaaatga tcaaattagt
    69601 agcaatcgat ttggacggta cattattaaa tgaacaaaag ctgatttcag atgagaataa
    69661 acaagcatta gcacaagcaa aacagcaagg ggtcaagatc gttctatgta caggacgccc
    69721 cttagctgcg atggcgcatt atctgcaaga attaggactg gtagatgaag gtgactacag
    69781 catcactttc aacggcggtt tggtacaaaa aaatgatact ggtgaaatca tggaaaagaa
    69841 agtgatggaa gtatcagata tccaacgctt atacaaactg gctcagcaat tggatctgcc
    69901 actagatgtt ttgtctgaca atgtggtttt acagctgcct agtgccccaa ggaagcaatc
    69961 cttgtacaat gtgttgaata agctgctgca attccaacca gcggatataa gcgatattac
    70021 agatgaattt gtgcttaata aggcagtaat cgcttatgac caagaagaat tagatcctaa
    70081 aatcaaagaa ataccagcag aattccatga aatgtatgag atcatcaaaa caagaagtat
    70141 gcttttggaa tttatgccaa aaggtgttac aaaagcttat ggtatttctt tattggcaaa
    70201 agatcttggt ttgaaacaag aagaaatcat ggcgatcggt gatgaggaaa atgatttacc
    70261 gatgatccaa tatgctggac taggcgtagc gatggagaat gctgtgcctt tcgtcaaaga
    70321 agcagcagat ttcgtgacag ccagcaatga agaaaatggc gtagccaaag tgatccaaaa
    70381 atttgtatta gagtaggggg agtcaaatgg gattttttga taaaatcaag cgtgctttta
    70441 ctggcgaaga gaaaacagaa gaagttgaag tacaggagaa gtacgacaag ggtttagaaa
    70501 agacgcgtaa aacatttggt gaacggatga atgagttgtt tgccaatttt cgaacagtcg
    70561 atgaagactt ttttgaagaa ttagaagaaa cacttatcgg tgcagatgta ggttttgaaa
    70621 cagcgatacg aattaccgaa gcattacgtc aagaagtgaa actcagaaat gcgaaaaaat
    70681 cggcagaagt ccaaaatgcg atcatcgaga aacttgtgga tctctatgaa gcggaaggaa
    70741 tcaatgaagt aaatgaacta aatatccaag aagacggact aacagttatt ttgtttgtcg
    70801 gtgttaatgg tgtagggaaa acaacaagta ttggtaaact tgcccatcag ttcaaaaacg
    70861 aaggtaaaaa agtattgatg gcagcagcag ataccttccg cgctggagca atcgaccagt
    70921 tagttgtctg gggcgaacgc gctggtgttg aagttgttcg tggcaatgca ggaggcgatc
    70981 cagcagctgt cgtattcgat gctttggaaa gagcaaagac agagcaggca gatgttttac
    71041 tagttgatac tgcaggccga ctgcaaaata aagtgaactt gatgaacgaa ttagaaaaaa
    71101 taaaacgagt aatccagcgg gaattaccag aagcacccca agaaacactt cttgtattag
    71161 atgcaaccac tggtcaaaac gcgatggttc aagcaaaaca attcaaagaa acaacagatg
    71221 tgaccggtct tgttttgaca aaattagatg gtacagcaaa gggcggtatc gtacttgcta
    71281 tccgtaatga attgcattta ccagtgaaat tggtcggtct tggtgaagga atcgatgact
    71341 tggagccgtt tgatccaaat gattttgtcg ttggattgtt caaaggatta ctaaaagaag
    71401 aataacccat gtctaaaaag caggagctgt gacaaaagtt gcagctcctt gtttgaatga
    71461 ttgtttttaa catagctgtg tttttgatgc cttcattttt atacttattt gtaagcggtt
    71521 ctcaaacaat ttcgttcttt ttcttagact ttttgattat aattagattc atatgaattg
    71581 gaggtcactt aatgatgaat tttaagcaat tattattgca tgtcaatgcg cgccctttta
    71641 tcgaccaagc tcgatttggt atagaacggg aaggacagcg ggttgatctt gcaggaaatc
    71701 tagcaaaaac cgatcatcca gcaatctttg gcgatcgatc ctatcacccc tatatccaaa
    71761 cagattttag cgaaacacaa acagagatga tcacccctgt taccgattct attcccgaat
    71821 tatttcagta tctcgctgct gtttatgatg tgactgctcg ttctataccg aaagaagaga
    71881 tgatctggcc attaagtatg ccacctgcct taccggaaaa agacgaagag atcattattg
    71941 caaaattaaa aaatttcgaa gatgtcttgt atcgacgtta tttagcaaaa gaatacggga
    72001 agcgaaaaca gatggtaagc ggtattcatt tcaattttga atttggcgat gagttgctaa
    72061 gaacattgtt cagccatcag gaagaatttc aagatttttc cgaattcaaa acagaacttt
    72121 atttgaaaac agcgagaaac tttatgcgct atcgctggat gatcacttat ttattcggtg
    72181 cttcaccaat gagtgagaag aactactttt tagatgaatc acatccgcaa gaacctgttc
    72241 gcagtattcg caacagtgcg ctgggctata cgaatcatcc aaatgtgaaa gtttcctatg
    72301 cttctatgaa acagtattta gcagatatcg agcgaatgat cgaagaaggg aaactttcgg
    72361 aggagaaaga attttataca ccgcttcgtt tccgaggcgg aaagaaagtc gcagatttag
    72421 caacaacagg tgttcgttat attgaattgc ggaatatcga tttgaatcct tatgcaagat
    72481 tgggtatcaa tccagagcaa gttcggttct tacaattatt cctgatgtac atgttatgga
    72541 cagaagaaaa agaagactgt gaccaatggg tagcagaagg tacgactcga aataacaaag
    72601 tagcactaga acaaccatca gatcaaacag aatttcatca agaaggtaga gaaattcttg
    72661 aaggaatgaa gcaaatgctg gttgaattgg attggttgga ttctctttat ttagtagagg
    72721 aagcattgac tcaaatggat catcctgaac aaacgttagc agcgaaactc tatcaagaag
    72781 cacagctatc gagtcagcaa gaagttgctg tggcattggg acatcaatat tataaagaaa
    72841 gccatgaacg tccctatcag ttggccggtt ttcgcgaaat ggaactttct actcagatat
    72901 ttatgttcga tgccatccaa aaaggtgtcc aagtcaaagt attagatgag tcggatcaat
    72961 ttttgcgtct gcaattccaa gaccatgtag aatatgtgaa aaatgcaaac atgacaagta
    73021 aggacagcta tatcgtccca cttatcatgg aaaacaaaac agtaacgaaa aaagtcttaa
    73081 aagaagctgg gttccgggta ccaggaggcg cagaattttc atccatggaa gaagcggtaa
    73141 aagcttatcc gagatttgcc gagcaggcat ttgtgatcaa acctaaatca accaattacg
    73201 ggttaggtat cacgattttc aaggaaggag ctagtctgga agattatcaa gcaggtttag
    73261 ccattgcttt tcgtgaagac agttcggttt tagtagaaga atttatgccg ggaacggaat
    73321 atcgtttctt tgtgatcgac ggagaagtcc aagccatcat gttgcgagtc cctgctaatg
    73381 ttattggtga cagtatccga acagtgaaag aacttgttga agaaaaaaat agtgaccctt
    73441 tgcgtggaac gaatcatcgt gcacctttag aattgatcca attaggtgaa ttagaacaat
    73501 tgatgttgaa agaacaaggg ttgacgatcg aatcagttcc ccaagccaat caaattgttt
    73561 atctaaggga gaactcaaat atcagtacag gtggtgattc gatcgatatg actgatgaat
    73621 tttctgaagc ttacaaaaaa atcgccgttt ctgcggtaga agcactagga gctaagatta
    73681 gtggtatcga tttgattata ccagataaag aaatcgatcc tacaactgat aaaaaagcat
    73741 atgggatcat cgaagcaaat ttcaatccag ccatgcatat gcatgtttat ccttttgcag
    73801 gaaaaggcag aagattgacg atgaatgtat tgaaattgtt atatcctgaa gtattttaaa
    73861 agaaaaagct tttgacagat tgtcctattt gatgtcaatc tgatcaaaag ctttttttgc
    73921 atgtaaaaat ttatgtgttt tttcgtttta aaataaacga tcccagaagc tttttttctt
    73981 ttttggtttt tctttttcag ctggcgaaga gttttcttct gggtattttt tttcgatatc
    74041 aatcacaggt tcatttactg cttcttttgc tgttaagagc aatccgaatt cctcaggatt
    74101 tgcagtgacg taatcgttga ctacagtgaa acggctattg tttttcgttg ctagctggat
    74161 atattggttt tggacagaaa ggggtagagc cccattcaag agtatggaag catctggatg
    74221 ttttttgagt tcttttaaaa agttttcttt gttttttggt tggatcattt cagcaacagt
    74281 catactaaga tagcagcgtt ccctgaatgt ccctaaatat ttatgctgtt cttcagggtt
    74341 cactaaaggt gtaccataaa gtcccttatc caaatggctt tttacatcat cttgtgccat
    74401 aaaaaatacc ctccttcttc tctttgtctt tcttacgatt atagcatatt cccaataata
    74461 cctaaaacat atgaaaaagc ggttgctttt gttcaacgat tcacttaaaa taagaatgaa
    74521 aatcattctc aattagaaag gtggattgga tgcgctacgg acgactagta gcattattag
    74581 ttattttaag tagtatttca ttgttcatcg gagtatcgaa tgtacaattg tcagaactgc
    74641 tccagttaga tgggcaaagc ttacaaatct tgctagtgac tcgtttgcca cgaacgattt
    74701 gtttgatcct tgtgggagcg accagtagta tttgtgggtt gatcatgcaa catttgaccc
    74761 aaaataaatt tgtttcacca acgactgcgg gcacgatgga tagtgcgcgt ttaggtattt
    74821 tagtggctat gattttccta cctggtgcat ccttgattgt ccgatccttg acagcatttt
    74881 gctttgcttt tgcaggaaca ttgctttttt tatcccttac gcgattgttc ctccagaaaa
    74941 atcaattgat gcttccgttg attggagtca tgttagggaa tatcattggt tcagttgcta
    75001 ctttttttgc ttatcaattc cagttggtac aaaatatgac ttcatggctt caagggaatt
    75061 ttgcgactgt gatacgagga aattatgagt tattgtatgc tgttgttcca ttgttgctct
    75121 tggtttggct atttgcttac cgatttacga tcattggtct gggcgaatcg tttgcagtaa
    75181 atctgggaat agattaccag aagatgcagt ttttaggcat tggcttagta tcattggcta
    75241 gtgcagtcat gttgatcatg gtaggaagca ttccttttat cggagtgatc attccgaatc
    75301 ttgtctctag aatatatgga gatcaagtgc acaaaacaat tggcgtaact gctttagcag
    75361 gtagtttgtt cttagtattt tgcgatcttg tcgctcgcgt gttgattttt ccttatgaaa
    75421 taccagtcag tgtgatcgtt ggaatcatcg gtggggctat cttcctttat cttctgataa
    75481 ggggacgacg atatgcttaa aaaaaagcca tctattttta ttggtatgct tgttcttgtt
    75541 ttatttgtta caggaatgta cttgacgatc catacatatg gaaactggca ttttgcatgt
    75601 gcattgagga gtaagaaaat ttttgcattt atccttgtct cgctagctgt cagcagtgcc
    75661 acaatcagct ttcagacaat tacgcataac cagtttttga ctccttcagt attgggactt
    75721 gagtcgttat atgtccttgt ccaaacggtc cttttcttct ttatcggagg agtgacgatg
    75781 cttcagcaga caggtacagt ttttttctta ttgaacgttg ggctgatggt cgggctgagt
    75841 ctattgttat ttttctttct tttgaaaaaa atgagagcga atcttttttt attactgatg
    75901 tcagggatga ttttaggtac gctttttggt agtgtcagta cctttttaca agtcatcatg
    75961 gatccgaatg aatatgattt gcttcaaggc agattatttg caagctttgg caatatccag
    76021 agtcagtatc ttttgcctgc ttctttgatc attatcggct gctggtacct gttatttcga
    76081 tatcgacatg tgctagacgt tttccatctc ggaaatgaac aagcagtaaa cctcgggata
    76141 gacacagatc gttttgaatt tttgatttta tgttgtgtca gtcttttgac agggacatca
    76201 acggctcttg tgggtccagt tactttttta gggtttattg tcgcaaatat cagttatcgt
    76261 gtcttttcta cttatcgtca tggtcagcta tttatcggaa gctttctggt agctatgctg
    76321 tttctgacag gaggacagct cgcagtagag cagattttcg gctggaatac aacagtgagt
    76381 gtcgtcgttg aatttgtcgg aggaatttat tttgtcacaa aattgattcg cgaaaggaag
    76441 agtatcctat gattgattta caaaaggtca ataaactgta ccatggaaaa tcagtggtta
    76501 aagatgtaca gttaacgatt cctgaaaaga aattgactgc ttttatcggt ccaaatggtg
    76561 ctggaaagtc aacggtgttg tcgatgatca gtcgtttgat accaaaagat acaggtgaaa
    76621 tctatttaga ccataacgaa gtaaaggctt ggaaatccaa tgaattagcc aaaaaattat
    76681 cgatcctacg acaatcgaat gaaataaatg tccaaatcac cgtgaaagaa ttagtagaat
    76741 ttggacgatt tccttatacg aaaggaaaat tgacgacaaa agacgaggaa atcgttcagg
    76801 aatcactgga acaccttggg ttagaagaaa tagcggatca atcgattgac actctttcag
    76861 gcggtcaact ccaacgtgcg tatattgcaa tggtgctagc gcaagacacg gattatattt
    76921 tactggatga acctttgaac aatctagata tgaattttgc ggttcaaatc atgcagattt
    76981 taaaaaattt agtacaagaa atcgggaaaa caattgttat tgttcttcat gatatcaact
    77041 ttgctgcaag ttatgcagac gaaattgttg caatgaaaga tggacagtta tttacgcaag
    77101 gaacgaccca agaaatgata aaaaaagatg tattggatga attatacgaa atggacatac
    77161 ggatttgtga gattgaaggc cgcagattct gtctttattt ctaaaactaa cattaggaga
    77221 gaagagatga aaaaattagt agtaggtatc ttgattctag catcatttgg tttagcagca
    77281 tgtggaaata gcaacaacac cagtcaggca gacacaaaaa aaagcagcac acaaactgaa
    77341 actacattga cgataacaga tagtaatgga gaccaaatcg aggtgccaaa taatccagaa
    77401 aaagtcgtcg tattcgacaa tggttcttta gatacgatgg atgctcttgg tgttggagat
    77461 aaggtagttg gagcagctac aagcagcctt cctgagtatc tttcatccta taaaaaagta
    77521 gaatcagcag gtggaataaa agaaccagac ttagaaaaaa ttaatcagct tcagccagat
    77581 ctaatcatca tttctggccg acaaagagat tttcaaaaag atctaagtca aattgctccg
    77641 accattttcc tttctttaga tgcgaaaaat ccatgggaat ctttccagca aaatgtcact
    77701 gctttagggg agatctttgg taagcaagaa gaagctaaaa ctcaattaga ggaattatct
    77761 agtgcaatcg atcagacgaa aaagaaagca gaagctactg acaaaaaagc actagtcaca
    77821 cttgtgaatg aagggcaatt atcagcctac ggatctggtt ctagattcgg tttcatccat
    77881 gatttatttg gctttgaaca agcagatgat caaatcgaag catccactca cggtcaaagt
    77941 gtttcttatg aatatgtgct ggaaaaaaat ccggatatct tatttgtagt agacagaaca
    78001 aaagctattg gtggagacga cagcaaagat gatatttctg ccaatgaact ggtagcacaa
    78061 acgaatgctg gtaaaaatca gcagatcatc tcccttgaac cagatgtctg gtatttaagc
    78121 gggggcggtt tagaatcaat gaaactgatg atcgaagatg tgaatcaagc atttaaatag
    78181 cataaataac agaggattaa actctcatac tatgtaacaa taatgtttct tacattctta
    78241 aatagcaaga gcctatcctc aaagaagtta tcaaaaacca tccgtaaaat cgtattgatg
    78301 attttacgga tggtttttat ttatttgaga aatctttttt caacgtgaat tcattatcta
    78361 catcatacgg gttgattcta gaatggggag tggcaaaaaa tagtgtgatc cattttttca
    78421 gcatcaagat cgcctccttt gatttgaatc aaaggtacaa agcgaaactt agataaaact
    78481 taaatttaga tatttttatt ttgtaccgat ctcttcttta aacgatgttc catctgctgc
    78541 ttctcggcaa taagtccact agactagaaa atatgagaag ctattttctg tccagcgttc
    78601 ttattactca aagcaaatcg cagttgtcac aatctcttct aaacgatgtt ccatctgctg
    78661 cttctcggca ataagcccac tagactagaa aatatgagaa gctattttct gtccagcgtt
    78721 cttattactc aaagcaaatc gcagttgtca caatctcttc taaacaatgt tcaatcagct
    78781 gaccttcggt attagctcaa agcactgatt tcacaacctc tatttaggca tgtgtctcag
    78841 caagcggttg atagttgatg atctgcattt ttcgataaaa atcggcggga agcttactcc
    78901 accgttttaa taattgatag aaataactct cttctgcttt gattttatac tcgcttaata
    78961 tcaatccaaa actattcgtt ttttttgaag ctaatttttt ataaatatcc aatgctttgg
    79021 ttttatcttc attgacaaag agtgttttta cttcaatata agaaccctcg atattttgtg
    79081 tttcttcgat aaaatagatg ttttttatat attccttcat agtgattcct ccaaagaagt
    79141 cttttatttg ataagtttac tctaccgaag agttgttaat aatccgtgaa caaaaagtaa
    79201 ttctttttcc aatagttgtt aaaggttttt tattttttat agtatttttt gttatttaag
    79261 aaaggaataa ggttaaacaa ataacaggtt gctttttggg tctttttccg ttcaagaaac
    79321 tgaacgaaga aaagggaaag ttgtctcttt tgtgataaga gaaatcataa taaacgaatg
    79381 acttactttc caataaattg agaacagtca gaaccagaca aattagttgc atctgatgaa
    79441 taaagtgatt attctatgac atgaggtgat acagatgaaa ttagaagtga caaaagaagc
    79501 acaagaagta ttgaagaata aattagaagc agacgatcaa cttttattag atatcgaaaa
    79561 cggtgacggt ccatttgcag aaagccaagt cagttgccaa ttggatacgg catttcgatt
    79621 gatcattgtc aaaaaagata cacaaacaga tctaagtctt tattctgtag tggctgatac
    79681 accagttgga ccaatcaaaa tcaaagacag tgcaatactt tacatggatg atccatccac
    79741 acttgcttta gaaccaactt ataatagttt acaattaaaa ggaccaagcg gcttgagaaa
    79801 aggcaacttg caagttgttc gaaaagacta gagggataaa atgggaaaat tggcgatcat
    79861 cagcgaccta catgtggaca tcaataaatt cggcgaatca gagctgatgc agctttggca
    79921 agttttgcaa aagcacaaga tcactcggct tcatctagcc ggagatacgg ctaataaagt
    79981 agaccgttgc ctagctgttg tcgaattttt cgtcaataaa ggattatcta cgacatttca
    80041 tttcggcaat cacgagttgg cagatgtgcc caatgaacag atgatggacc attttccaga
    80101 cccacatttt ttaaatgaac ggtatattgc tttaaatgag cagaccgttc ttttagggat
    80161 gaatggctgg tacgactatc agttttccga attgaaagat tacgaggcaa tcgtacgaat
    80221 gaagcgtttg tattggtatg atcggttcat ccagcgtggg aaaacagatc tcgaggtcaa
    80281 tgcagaaatg cttgcagctg caaaaaattt gctagaccag ctggaagcaa aaaaacttga
    80341 ggtgatttta tccactcatt tcgttcctaa acgggcattt atcatgtatc aatctgctcc
    80401 ttatgagcgt tggaacaaat taaatgcatt tttaggatca gaatcattcg gagaattact
    80461 tgaccgttat tcaaatatca aacaagtagt ttttggccat acgcatcgtc gctttgaaga
    80521 taaatccatc ggtcacacga tttacagctg cagacctttt ggttattatt atgaatggca
    80581 gctgacccga gattttgtct tgaaagaaca gttgctagac agctatgatc ctatgaaatt
    80641 acgtgtcctc ttgcgtgccc atcacccagc ttttcaggcc tatcaaacac aacatttgca
    80701 agaggaattt gaacaagcga tgacaatcgt tccgtattga gacagcatta gtaatgtgta
    80761 aaagaaaata ccttgtaaaa cataaggata agtaagagca gtagatccat ttatcgtgga
    80821 tatgctgctt tttttgcgga aaataatcag cgaatgttta tttgatcgga tgatttgtaa
    80881 ctcgcagagt actagatgca agcgtgtatt ctttttttga acgataatca caaaaaaaaa
    80941 tataatatac attttttatt taattataat taatattgat tgaagtctag gcagtcaagt
    81001 cacattttga tagataggag ggggacttac gaattatttt aaaggctatg acagctgtat
    81061 ttctagattg tgtttgcatc aagttgcaat aaaaactaga aatcaaatcg ggctgataat
    81121 catttataac taatcgatac ataggaccaa atataggtct atgttctttt atttcataag
    81181 tatcgtaaaa cagaattttg ctatggatta atccaatcga ctgatatgtt tagtaaataa
    81241 agaaagagga atgtcaatga tgaaaaaaga aatcgtatta acagcagcaa tgatgttatt
    81301 cagcatggta gcaagtacga cttttgtttc tgcaactgaa gtatacccaa aggaatataa
    81361 cacagaagga acgattacat ttgaagcagg agatgagggt gtaactcctc ctgttgatcc
    81421 agagaatcct gatcccaata aacctgtcga tccatcagat cctccaagcc ctggaacagg
    81481 aggggcatta tcgattgatt atggatcaaa attcaaattt gggactcaaa aaatttctac
    81541 tgcggataaa acgtattatg cagctgctga tgtgatgaac gatgggtcta gaaaaccgac
    81601 atatgtccaa gtgacagata ggagaagtac cttatctggg tggaaattaa gtgtctctca
    81661 accagaacag tttaaaactg ccagtgggga tgaactagtt ggagcacagc tgaaatttac
    81721 gaaagggcag gctgtttctt tggttgatcc aacatatacg ccgcaaacgg tgaattctga
    81781 attaacgttg acaccgggag gaaacaatac gttagcaatt aatgctaaat caggaacagg
    81841 tgtggggact tgggtctatc gatttggtgc aaatgaaaat gaaaatcaag atgcggtaca
    81901 gctttcggta cccggtaaat ctgtcaagtt agcgcaacaa tattccacta aattagtttg
    81961 gacattagaa gatacaccta acaactagtt tactgaaaag aactgttaaa aataaatacg
    82021 tagtcatatt gtcttgcgag gtaatcgagc aaaaattgtc aaaggctagg ctaaatttgt
    82081 ttggatacga atagttcatc taggaattta acgatcagga ggaaaagata tattgaaaaa
    82141 gaggaggatc gtgctcattt taagcagtct cttagtgact aatatctttc cgatcatagg
    82201 gtactctttg gaattgaatc agttggagca tggaaataga agagacgaag aaagcaaact
    82261 cacttcgaca ttcgacagtt taatagaatc caaccagaca caagaaagca gtgaggattt
    82321 aagtatttcg agtagtggag agaccactga caacgtagaa gctgagggtt cggacaaaca
    82381 aggactagaa gatgcaccaa tttctgcggt tgagctgcct gacgatccca atattatttc
    82441 tatcgataaa atttttcaaa cacctatcgg tactagcacg tccatattgg aaaatgggaa
    82501 gttactgcag ttgaacccag cagaaaggtc tcaaagagga gctatttggt caaataagaa
    82561 gattagttta ctctcggatt ttacatttaa atcttattta tacttaggaa atcaacgaga
    82621 tagagcggga gatggcatga cctttacatt gactggcgat cctagaatgg ctagtaatcc
    82681 cagtcaagtt attggatcgc caggtatggg aattggctca tattctactc gttctggcca
    82741 accttacatt gcgaatgcgc tctcgattga gtttgatacg tataaaaata gtggttcttc
    82801 tgatcgaatg gatcgagaga taactgctga taatagaggg catggacatg tcgcttttgt
    82861 cacgcctaaa ccaaataata ataattattc tggagagcat actggcgtga cggtagctcc
    82921 tacatttctt tctaatggca catggcgctt gttaataatt aaatgggacg cggagcaaag
    82981 aagtcttact tatgatttgg aaggtgtcgg tcactcttct cggattatac ctgatctcat
    83041 taggcagttt ggttctacag aagtaaattg ggggtttact tcttcaacag gtactttttt
    83101 tcaagaaaat gctgtcgctg tcacgcgact tccatcgaat gtcacatcaa cagctgatgt
    83161 aaaagtcaac gatagtgatt atggggccat cgctgaagct ggaggaaacg ataagataac
    83221 tatcagaaat acattgaagg tcgaggggga ttttcttgaa tataagaaaa tgcagactag
    83281 tatcgacctc ccacaagaat taactattcc cgagcatatc ttgatcaatg gaaatcaaat
    83341 tgatgccaaa gatatcttga taaccggaaa tcgagtcacg ctaaatctga cagattattt
    83401 tattgctgga gatacgttaa taatcgaatt ggagacaact ttgcaggaag taattcctga
    83461 aaaagtactc actatgcatt ttgaatacct tgaaaacggg aatttgattg agcaatcgaa
    83521 tgaaataaac ctaaagatcg caaagctgaa ggagatagat atccatgttt attataaaga
    83581 taaagacagt cagattgata ttgctgaaat gaaaacaatc actgggaaaa taggagagaa
    83641 gtataaagaa actcctattg atattgaagg gtatgttttt gactcggatt cagcgaatac
    83701 agaaggcatc ttctccgaaa atacagagga tatctatttt tattacagaa aaggcaaact
    83761 ttatctctca actgctcctc aatatgtcaa ttttggaaaa cataaaatat ccagtagacc
    83821 attaagtgaa ttcggacagt tttcaggtgg gttgaaaatt atagatgaac gggcttttgg
    83881 aagttggaaa ttacaattga aacaagagaa agttcttaca aatggagatt ttgagcttcc
    83941 agaagctctt tcctttgtta cctctgaaaa tacaacggtt atagggacat ccgctgttac
    84001 gattttcgaa agtgatcaaa agggtgaaag cgatttgtcc tctcttttag attctacagc
    84061 tcatcgtgga atcagaatag atattcctgt agaaaaccaa agaatcggaa cctttgaggg
    84121 gaaactatct tggatacttg cagatgtccc aggaaattaa caggaagaga agaatataac
    84181 aaaattattg agtttcaaga agggcacagg taccataggc tcttgtgtcc cacagagaca
    84241 agattttgtt atagtcttct cttacatatg attaaaggag cgattttctt gagaccaaaa
    84301 caacaattat ttataacact cctagttatt ttaggggcac tttttaacaa tatatcagtg
    84361 tcagctagtg catttaattt ttcagtgacg ccgataactt cagagaatca aatcgacaag
    84421 agaaaaactt acttcgatct tcaacttgat ccggatcagg aagtagaagt aaaagcggaa
    84481 ttgagaaatg atacagaaaa agaagtgaaa atcgatattt ctgtgaatag cgcaaccacc
    84541 aattcaaatg tgatggttga atacggaaaa aacgagattg aaaaagacat gagcctgatc
    84601 tttgatctgg tagattatgt gagctatcca cagatagtga cgctaaaacc taaaagtgtc
    84661 caaaccgttg cttttcatgt caggatgccg aatgagcgat ttgatggtgt attggctggt
    84721 gggatcacat tccaagaaat ccagacggaa aaggaccaaa cagaaactaa ggatcaaagc
    84781 ttatcgattg agaatgaata cacctatatt attgctttgt tgatgcaaca gacactgaac
    84841 gaagttgctc cgaaccttac tcttcatgaa gttaaaccag atcaaatcaa tgcaagaaat
    84901 gtcatcttag caaacgttca aaatgatcaa aaaacctata tcaatcaagt agttattgaa
    84961 acaaaaatta caaaaaaagg acattctgaa gttttatatc aagaggaaaa agaaggattg
    85021 cagattgcgc cgaatacaaa tttttctttt ccaactgctt taaatggtca accgctaacc
    85081 ccaggtgaat atcaccttac aatgactgtt ttaggaaatg aaaatgaaaa tggaaaattt
    85141 tcgagaaaaa aaggaaatac tacgatcaac tataccaatc aatgggtatt tgaaaaagat
    85201 tttacaatag acggaaaagt agccaaggaa ttgaacacga cggatgttac gattaaaaaa
    85261 gacaataatt ggatttatat cttagtagct tcacttttct tattgtttat tttattatgc
    85321 atacttttgt ttgttttgag aaaaaaagaa gagaaagaaa agtaaggtta agataacaaa
    85381 tagtaaattt ttattattgt aggatggttg ggctcttttt ataacaatat aaaatatacc
    85441 attttattaa taaaaatgca tactagtaaa tgatataatt ctaataacag gtttgatcgc
    85501 gagaaaggcc aaataaaacg ctctccaaaa tgttaaaaaa aagacaggac gatgtatatt
    85561 atacaaacaa gaatcgctga caacagtgac tcggatccag gaaatcagtt ttatccccag
    85621 ctagttggtg aatgcatgga aagtaatata cgtagaaaga gctgatgact aatgaattat
    85681 gagttttttt taagcaaaga agatcacaga agttattcat tacttaaata tttagaagca
    85741 agctcaaatt tatcagagtc aatatcgaat gttcaagaag agttgtcgct atcgacattt
    85801 ctcttgaaaa aaacgatcga taagctgaaa catgatttac aaaagttcga tctagagaaa
    85861 aatttgcgag taaccgtcag tgaattggat atatgtctgg aaattaatgg aaaatgttct
    85921 agcaaagctc tgttatctcg ttatataacg gattctttat ctatgaaaat ggtattggct
    85981 ttctttcagg aaaaatatat ctcagtagaa aattttgcta aacagcatca cgtgagttat
    86041 tctgtggctt ataaagtatt acaaagacta aaaagaaatc taaaaaaata tcaaattttt
    86101 tttgaaaaga gaaagttga
//
LOCUS       DACDLM010000003        76142 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.003, whole genome shotgun sequence.
ACCESSION   DACDLM010000003 DACDLM010000000
VERSION     DACDLM010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 76142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76142
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.003"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            98..1162
                     /locus_tag="IV356_000176"
     CDS             98..1162
                     /locus_tag="IV356_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAP9013905.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            1408..1833
                     /locus_tag="IV356_000177"
     CDS             1408..1833
                     /locus_tag="IV356_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAP9013906.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            1826..2275
                     /gene="nusB"
                     /locus_tag="IV356_000178"
     CDS             1826..2275
                     /gene="nusB"
                     /locus_tag="IV356_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HAP9013907.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            2372..3226
                     /locus_tag="IV356_000179"
     CDS             2372..3226
                     /locus_tag="IV356_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HAP9013908.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            3227..4564
                     /locus_tag="IV356_000180"
     CDS             3227..4564
                     /locus_tag="IV356_000180"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HAP9013909.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            4569..4793
                     /locus_tag="IV356_000181"
     CDS             4569..4793
                     /locus_tag="IV356_000181"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HAP9013910.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            4795..5685
                     /locus_tag="IV356_000182"
     CDS             4795..5685
                     /locus_tag="IV356_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAP9013911.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            5694..6512
                     /locus_tag="IV356_000183"
     CDS             5694..6512
                     /locus_tag="IV356_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HAP9013912.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            6619..7068
                     /locus_tag="IV356_000184"
     CDS             6619..7068
                     /locus_tag="IV356_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAP9013913.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            7086..8768
                     /gene="recN"
                     /locus_tag="IV356_000185"
     CDS             7086..8768
                     /gene="recN"
                     /locus_tag="IV356_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HAP9013914.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(8823..8939)
                     /locus_tag="IV356_000186"
     CDS             complement(8823..8939)
                     /locus_tag="IV356_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HAP9013915.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(9012..9968)
                     /locus_tag="IV356_000187"
     CDS             complement(9012..9968)
                     /locus_tag="IV356_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAP9013916.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            10139..10507
                     /locus_tag="IV356_000188"
     CDS             10139..10507
                     /locus_tag="IV356_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HAP9013917.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            10677..11108
                     /gene="mraZ"
                     /locus_tag="IV356_000189"
     CDS             10677..11108
                     /gene="mraZ"
                     /locus_tag="IV356_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HAP9013918.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            11129..12088
                     /gene="rsmH"
                     /locus_tag="IV356_000190"
     CDS             11129..12088
                     /gene="rsmH"
                     /locus_tag="IV356_000190"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HAP9013919.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            12093..12494
                     /gene="ftsL"
                     /locus_tag="IV356_000191"
     CDS             12093..12494
                     /gene="ftsL"
                     /locus_tag="IV356_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HAP9013920.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            12495..14687
                     /locus_tag="IV356_000192"
     CDS             12495..14687
                     /locus_tag="IV356_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAP9013921.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGIAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            14713..15675
                     /locus_tag="IV356_000193"
     CDS             14713..15675
                     /locus_tag="IV356_000193"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HAP9013922.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            15689..17050
                     /locus_tag="IV356_000194"
     CDS             15689..17050
                     /locus_tag="IV356_000194"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HAP9013923.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            17076..18164
                     /gene="murG"
                     /locus_tag="IV356_000195"
     CDS             17076..18164
                     /gene="murG"
                     /locus_tag="IV356_000195"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HAP9013924.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            18179..19399
                     /locus_tag="IV356_000196"
     CDS             18179..19399
                     /locus_tag="IV356_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HAP9013925.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            19555..20880
                     /gene="ftsA"
                     /locus_tag="IV356_000197"
     CDS             19555..20880
                     /gene="ftsA"
                     /locus_tag="IV356_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HAP9013926.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            20903..22144
                     /gene="ftsZ"
                     /locus_tag="IV356_000198"
     CDS             20903..22144
                     /gene="ftsZ"
                     /locus_tag="IV356_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HAP9013927.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            22161..22838
                     /locus_tag="IV356_000199"
     CDS             22161..22838
                     /locus_tag="IV356_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HAP9013928.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            22852..23451
                     /locus_tag="IV356_000200"
     CDS             22852..23451
                     /locus_tag="IV356_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HAP9013929.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            23466..23753
                     /locus_tag="IV356_000201"
     CDS             23466..23753
                     /locus_tag="IV356_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HAP9013930.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            23802..24584
                     /locus_tag="IV356_000202"
     CDS             23802..24584
                     /locus_tag="IV356_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HAP9013931.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            24605..25312
                     /locus_tag="IV356_000203"
     CDS             24605..25312
                     /locus_tag="IV356_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HAP9013932.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            25574..28372
                     /gene="ileS"
                     /locus_tag="IV356_000204"
     CDS             25574..28372
                     /gene="ileS"
                     /locus_tag="IV356_000204"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HAP9013933.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKSYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(28421..29947)
                     /locus_tag="IV356_000205"
     CDS             complement(28421..29947)
                     /locus_tag="IV356_000205"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HAP9013934.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(29962..30609)
                     /locus_tag="IV356_000206"
     CDS             complement(29962..30609)
                     /locus_tag="IV356_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HAP9013935.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(30793..31122)
                     /locus_tag="IV356_000207"
     CDS             complement(30793..31122)
                     /locus_tag="IV356_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HAP9013936.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            31299..32027
                     /gene="sfsA"
                     /locus_tag="IV356_000208"
     CDS             31299..32027
                     /gene="sfsA"
                     /locus_tag="IV356_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HAP9013937.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            32043..33056
                     /locus_tag="IV356_000209"
     CDS             32043..33056
                     /locus_tag="IV356_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP9013938.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            33056..34333
                     /locus_tag="IV356_000210"
     CDS             33056..34333
                     /locus_tag="IV356_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAP9013939.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            34396..37098
                     /locus_tag="IV356_000211"
     CDS             34396..37098
                     /locus_tag="IV356_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP9013940.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            37250..37567
                     /locus_tag="IV356_000212"
     CDS             37250..37567
                     /locus_tag="IV356_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP9013941.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            37597..37917
                     /locus_tag="IV356_000213"
     CDS             37597..37917
                     /locus_tag="IV356_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAP9013942.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            38025..39485
                     /locus_tag="IV356_000214"
     CDS             38025..39485
                     /locus_tag="IV356_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP9013943.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            39553..39774
                     /locus_tag="IV356_000215"
     CDS             39553..39774
                     /locus_tag="IV356_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013944.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            39805..39987
                     /locus_tag="IV356_000216"
     CDS             39805..39987
                     /locus_tag="IV356_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HAP9013945.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            39987..40400
                     /locus_tag="IV356_000217"
     CDS             39987..40400
                     /locus_tag="IV356_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HAP9013946.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            40523..41704
                     /locus_tag="IV356_000218"
     CDS             40523..41704
                     /locus_tag="IV356_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP9013947.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            42093..42166
                     /locus_tag="IV356_000219"
     tRNA            42093..42166
                     /locus_tag="IV356_000219"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:42127..42129,aa:Arg,seq:cct)
     gene            complement(42235..43374)
                     /locus_tag="IV356_000220"
     CDS             complement(42235..43374)
                     /locus_tag="IV356_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP9013948.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEVK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINAVFDSLYKNDN"
     gene            complement(43490..44125)
                     /locus_tag="IV356_000221"
     CDS             complement(43490..44125)
                     /locus_tag="IV356_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HAP9013949.1"
                     /translation="MAKKVMGQDGKMYKVSKPFYKKVWFWVLILLLFFGIGGALSGGE
                     NKDSATATSTSTNKETTKETTAKEEKTYKIGDDVAVGKMEYKVNSVEVVKQVGPSVLP
                     TNAKDTFLVVDLSVKNAGDKAVTVDSSFFKLKADGKTFEADSAASMSANQDENGNITN
                     SFFMESLNPDMQQTGKIVFDISEAQANAQNNVLQAQTGYFGTETVSIALHN"
     gene            complement(44208..44630)
                     /locus_tag="IV356_000222"
     CDS             complement(44208..44630)
                     /locus_tag="IV356_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAP9013950.1"
                     /translation="MYLKLKEMLSEYNLKLIYMEMEEPGFYYPKPRIVFLNEKLHEDS
                     SEAFHLAHELGHFIASHFEYSVLYDNSTTFHSKFETEADRIAIMILLNIFIENELTDE
                     SQFKLENFMEFYSINNKLRTECFNVCQSYFKKKYSYAQ"
     gene            complement(44648..44968)
                     /locus_tag="IV356_000223"
     CDS             complement(44648..44968)
                     /locus_tag="IV356_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP9013951.1"
                     /translation="MNPYEKIKELTKQNGISVRELEKRLGYSNGYFSKWKSVSPNSEG
                     LAKVSDYFGVSIDYLLGRDKKETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            45269..46045
                     /locus_tag="IV356_000224"
     CDS             45269..46045
                     /locus_tag="IV356_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HAP9013952.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            46060..46263
                     /locus_tag="IV356_000225"
     CDS             46060..46263
                     /locus_tag="IV356_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP9013953.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            46279..46617
                     /locus_tag="IV356_000226"
     CDS             46279..46617
                     /locus_tag="IV356_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HAP9013954.1"
                     /translation="MQYLEAKIPVPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            complement(46872..47537)
                     /locus_tag="IV356_000227"
     CDS             complement(46872..47537)
                     /locus_tag="IV356_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013955.1"
                     /translation="MSLIDFIKQFDWNNIVKTIKDFILPITSLVFSTFAFYISYTDRK
                     NKKFNLKLDFFAECEEWLIDRESDSKPDVYHQNKFRIIDSVLLTNNSSLPVTIIEFSI
                     SGIPDPLNAFTMIGDNYSVTVKSMYDELPHGIRAYSGKSLKKGADLSKFPPLSLPITI
                     PPYESKITTLVFRYDESLVEKNITINVLTSRGTAKFNRFVSSSQISQLDTGYAPPQLD
                     EFD"
     gene            47592..48290
                     /locus_tag="IV356_000228"
     CDS             47592..48290
                     /locus_tag="IV356_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HAP9013956.1"
                     /translation="MQELVILKNKEAVTTSIQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFSEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNTKVMEVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDENE"
     gene            48468..48809
                     /locus_tag="IV356_000229"
     CDS             48468..48809
                     /locus_tag="IV356_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013957.1"
                     /translation="MEKELSTLDQYLTDPSWGKSNIKETNNRKIRRNLLTDEELACDQ
                     DDLGNFVSIWDHVYLIHLSRKSKKPEYIYVIEDGLIDALEEYDRDNLIDISYYGSGKK
                     YIAEMEAEFDE"
     gene            48802..49473
                     /locus_tag="IV356_000230"
     CDS             48802..49473
                     /locus_tag="IV356_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HAP9013958.1"
                     /translation="MSENKGTTTFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            49479..50165
                     /locus_tag="IV356_000231"
     CDS             49479..50165
                     /locus_tag="IV356_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013959.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            50172..51023
                     /locus_tag="IV356_000232"
     CDS             50172..51023
                     /locus_tag="IV356_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAP9013960.1"
                     /translation="MADNKRYYYLKLKENFFDSDEMVLLESMPDGYIYSNILLKLYLR
                     SLKHEGKLMFNDRIPFNSTMLATITRHSVGVVEKAVQIFRDLQLIEVLDNGAIYMSDI
                     QSFIGKSSTEADRKRKYRKEIEEAKQNLITSGQMSDKCPDKTTPELEIELEKDIELEK
                     DIENVTPSKKSKAKPVRHKYGEYKNVLLSDEQMEKLKIEFPNDYQERIERLSEYCESS
                     GKTYKNYLATIRSWARKEKSESKNASSGYKRTGRREKLPEWAIDQEAYLKKKALERAN
                     RQSKAPF"
     gene            51035..51304
                     /locus_tag="IV356_000233"
     CDS             51035..51304
                     /locus_tag="IV356_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013961.1"
                     /translation="MKIDYLELINEIAKYKTGEEIEILRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLNELEQV"
     gene            51466..51786
                     /locus_tag="IV356_000234"
     CDS             51466..51786
                     /locus_tag="IV356_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013962.1"
                     /translation="MDKKAAWRKLMLLIQDENWQEDEAVVAEVQRLEKIANGRIRKKP
                     DKRKLRKGKIIVVLYEGNILMQGTARELSAETEYTSGTIRTYAWRNHVDKKGHEYKYL
                     EGSK"
     gene            51783..52172
                     /locus_tag="IV356_000235"
     CDS             51783..52172
                     /locus_tag="IV356_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013963.1"
                     /translation="MIPKFRAWYTPFKGKTIGQEMKYGQAGRLITHAEMAPDKYVLMQ
                     STGLKDKNGVGIFEGDVVLVNVSNGFDHLVNEKTVVQESEFHSGLVCKSLISGMEYRV
                     FKHKKMDYEYEVIGNIYENSELLEEQR"
     gene            52169..52762
                     /locus_tag="IV356_000236"
     CDS             52169..52762
                     /locus_tag="IV356_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HAP9013964.1"
                     /translation="MNKQETIKKLESIKAIGNDAIAACYNESMNAGITLMKKIDEPQK
                     HVMPKFFDKWAKQVLEKRDKFYAISLIARAGWGYGVDFELSENGLSSENKELLYWLVD
                     KCSDNYPNKKKAIEALLYGYEVEKEPLYHVKLKIPGVTYYLIQTFLMPGDTHMCFSAA
                     TERYGAKWKNTFTESEIKAIDERYWPFAVPVEEEAEG"
     gene            52759..53136
                     /locus_tag="IV356_000237"
     CDS             52759..53136
                     /locus_tag="IV356_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013965.1"
                     /translation="MKKLHQLISEKESELQNLEDSLGLGFPIVEQAKMTQISHLRLEL
                     EDLRQIEKSIQLNDNQQIVFEWLKLTAPTGKPMQVVFWMMNNAAWGHLDELRDPLMEL
                     TDKEQFEVLAAFAQWGLEQEEAE"
     gene            53133..53336
                     /locus_tag="IV356_000238"
     CDS             53133..53336
                     /locus_tag="IV356_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HAP9013966.1"
                     /translation="MNNRHRRITKLRKQELNVLKAKFEKEYGVSAEEAYKVASQCVAD
                     ASNAIRKFGISILSDDRKWEDIE"
     gene            53333..53542
                     /locus_tag="IV356_000239"
     CDS             53333..53542
                     /locus_tag="IV356_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013967.1"
                     /translation="MKVYVVRFGNKFYRSDERSIGNNVLFLVDFLQNARWFDNLEEAN
                     QVSRRLGGLTQVYELVTIDHEGVER"
     gene            53539..53832
                     /locus_tag="IV356_000240"
     CDS             53539..53832
                     /locus_tag="IV356_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013968.1"
                     /translation="MKLKDGFYASSHGIGGLMLGMPTKNPKTRKKPKFKVGDMVRCEA
                     EEFIYPFRGYVEHVYNHSAIIRIENTMECDKRLAKSKENLAVVRLVDMEVIKS"
     gene            53862..54302
                     /locus_tag="IV356_000241"
     CDS             53862..54302
                     /locus_tag="IV356_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP9013969.1"
                     /translation="MSVIPQLEGEEAIVNILENIDIKQTRKNARRLLKRYRNLERLVG
                     PVKIDFSVMTVTKNLKFTIDSQNEEIIEAISTRDSVIEALTRLSRIHFQVLYYSYCFP
                     NKMSMYQIGEKLGYSDRTIERMKAVALVEFAEAYKSGELISRTK"
     gene            54377..54844
                     /locus_tag="IV356_000242"
     CDS             54377..54844
                     /locus_tag="IV356_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HAP9013970.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQPR
                     EPKVTASYSLVPPSTADHIFEAERMLIDKEEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGMSIYVTAQRNNTSEESVKAESNKIIIQFASSLELVAFK"
     gene            complement(55254..55607)
                     /locus_tag="IV356_000243"
     CDS             complement(55254..55607)
                     /locus_tag="IV356_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013971.1"
                     /translation="MAKIDDYRSDMIEYIELFAKNSNNNIIIQTGGATICGTPIDFDA
                     EVKVNPLIDAMMDSFAEFRSKKIDDIEKDDEQSLVVKSIFLKDVTIIGERTTNIPFLV
                     VFADQISAISLGNLE"
     gene            56538..56882
                     /locus_tag="IV356_000244"
     CDS             56538..56882
                     /locus_tag="IV356_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAP9013972.1"
                     /translation="MTEEFYRWLLQLIREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            56887..57168
                     /locus_tag="IV356_000245"
     CDS             56887..57168
                     /locus_tag="IV356_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013973.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNIFGYSIEEINYYIDFAEAFIPMVR"
     gene            57271..57585
                     /locus_tag="IV356_000246"
     CDS             57271..57585
                     /locus_tag="IV356_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HAP9013974.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            57563..59257
                     /locus_tag="IV356_000247"
     CDS             57563..59257
                     /locus_tag="IV356_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAP9013975.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPGLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENAGTGFTPLVF"
     gene            59277..60455
                     /locus_tag="IV356_000248"
     CDS             59277..60455
                     /locus_tag="IV356_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAP9013976.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRAQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYKLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            60418..61104
                     /locus_tag="IV356_000249"
     CDS             60418..61104
                     /locus_tag="IV356_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HAP9013977.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKREEKIAAFTAAL
                     NKTFGQGDVK"
     gene            61104..62264
                     /locus_tag="IV356_000250"
     CDS             61104..62264
                     /locus_tag="IV356_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAP9013978.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTRA"
     gene            62274..63149
                     /locus_tag="IV356_000251"
     CDS             62274..63149
                     /locus_tag="IV356_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013979.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            63146..63457
                     /locus_tag="IV356_000252"
     CDS             63146..63457
                     /locus_tag="IV356_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013980.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            63447..63800
                     /locus_tag="IV356_000253"
     CDS             63447..63800
                     /locus_tag="IV356_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAP9013981.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            63790..64191
                     /locus_tag="IV356_000254"
     CDS             63790..64191
                     /locus_tag="IV356_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013982.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            64184..64588
                     /locus_tag="IV356_000255"
     CDS             64184..64588
                     /locus_tag="IV356_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013983.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            64600..65208
                     /locus_tag="IV356_000256"
     CDS             64600..65208
                     /locus_tag="IV356_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP9013984.1"
                     /translation="MAKTKTVVTTFDNVSIKRIAFNFKNAGNAIATNCNGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            65228..65590
                     /locus_tag="IV356_000257"
     CDS             65228..65590
                     /locus_tag="IV356_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013985.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            65593..65775
                     /locus_tag="IV356_000258"
     CDS             65593..65775
                     /locus_tag="IV356_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013986.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            65792..69211
                     /locus_tag="IV356_000259"
     CDS             65792..69211
                     /locus_tag="IV356_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HAP9013987.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     VTAGQSASESEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLTKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTL
                     IIGAVITAIAGVIAIIKNWGAITDWFKGIWSKFTDWLGGTWESIKEGASSVWDGVKET
                     WSGFVDWVQEIWQGVSDWFGELWSGLVEGASNIWQGVQETWQTFIDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTSISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAVATVIQNIWSTVSSWLGGIWNSISSTASNIWSSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISSVFDNLNISIPHIPLPHFKLSGEF
                     NPLKGKIPTLGVDWYAKGSVFNSPNIIGVGEAGPEAVLPLKRSVLQEIGDRILSSTSV
                     SSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKVQNDNASAWR"
     gene            69262..69999
                     /locus_tag="IV356_000260"
     CDS             69262..69999
                     /locus_tag="IV356_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP9013988.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVVGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFTCTGLSKIQIYRNGLR"
     gene            70009..72300
                     /locus_tag="IV356_000261"
     CDS             70009..72300
                     /locus_tag="IV356_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013989.1"
                     /translation="MIDNLLTIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNVGEISDLINDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            72324..74567
                     /locus_tag="IV356_000262"
     CDS             72324..74567
                     /locus_tag="IV356_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013990.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPYLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAETKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGNYDYSGNPNLLSKLSYDLIE
                     NQNTSAGTLSKGENSFKYNKISAETEGGVELYYKRRGIANWLPSNKTLVMTVKLRAGV
                     DYSPADGKKILIRYRFVDNGTGKIVLDLPINSNSITQEWKEFSITGTTPTFGPQAYHP
                     WIQFRAQDGILGEIEMSYDIKIEEGPTATPFQPNLLAEPYNMCREYPNENIVNPTVKF
                     PIKTSNNPISGFDISEELIIGETYTVSLKGTKPATKEFHLYYGEANYQQLQHQATLLP
                     VEGLTDVWSATFTARNTSETTNLLRVALWQKPNSATYDTVQIDWLKIEKGNTRTPNIS
                     EYKYRGTGMRDSNNPKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEINSQ
                     LTASINEVDTTAKDARTKANANATAIDELDNKIDERINDAATTAFYGAQGEVSNKTKV
                     AEYGVGTGYTTTAVGETHFERQSNGYVKCLKAGKYSISAQIRVQLGGKYASWLYTDLY
                     KDGTSVDNLVSYGVDALQNRFAASGNIVTDLEVNDVLNMRTEIGVADGILQFTSCRTL
                     VLTRLSD"
     gene            74645..74887
                     /locus_tag="IV356_000263"
     CDS             74645..74887
                     /locus_tag="IV356_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAP9013991.1"
                     /translation="MKDEAIQDVVERLVRIETKLDNYELLREKAESAKDRADQVYSIA
                     LNNAEDIKEMKANNKWSWGYMIGLGITIIGYFLTKL"
     gene            74903..75100
                     /locus_tag="IV356_000264"
     CDS             74903..75100
                     /locus_tag="IV356_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAP9013992.1"
                     /translation="MILPDKYYQVIKWTVLTVLPAASALVAMLGKAYGWNGTDMIVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            75111..76130
                     /locus_tag="IV356_000265"
     CDS             75111..76130
                     /locus_tag="IV356_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP9013993.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSDDKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RPDVNQAYNTLGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
BASE COUNT        26132 a        12336 c        15965 g        21709 t
ORIGIN      
        1 aaaaagaagt tttccggaaa tttttattta actgtcgtgt acgaagaaaa gtttgctata
       61 atggaaaaaa gcgtgcaaag aaagagggag tttcattatg atgctacgtg tagaaaaatt
      121 gcgcaaaaaa atgcaagaag aaaatttgga ttcatttttg gttaccagtc cgtacaatct
      181 tcgttactta acgaacttta caggtacgac aggattagct gttattactt tggaaaaagc
      241 attttttatt actgattttc gttataccga gcaggcggca gcgcaggctc aagggtttga
      301 aattattaaa aatgtcggac ctatttttga tgaggtagca aacttagtac gcaaagaaga
      361 actgcactca ttagcttttg aggaaacaac agtctcattt ttagaatatt cggttttaga
      421 agaaatcatc gatgcggaat tagtacctgt ttcacagatg atcgaagaac tcagagaagt
      481 gaaagatgaa gaagaaatcg ctattatcga aaaagcatgt catattgcgg atatggcata
      541 tgatcacatc ctgaaaatga tccaaccggg catgactgag attgaagtcg caaatcaact
      601 agacttttat atgcgttctc ttggcgcttc aggtgtttct tttgatacga tcgttgctag
      661 cggattgcgt tcggctatgc cgcatggtgt agcaagcaaa aaaatcatcg aacaaggtga
      721 cttgatcaca ttggactttg gttgctatta cgaagggtac gtttccgata tgacacgtac
      781 attcgctatt ggtgatcctg gggaaaaatt aaaagaaatt tatcaaatag tcttagatgc
      841 tcaattagca gttattgatg ctgcaaaacc aggaatgact ggtgtccaat tagatgcagt
      901 tgctagagat tatatttcaa aacatggtta cggggaagca tttggacatt ctacaggaca
      961 tgggatcggt ttagagatcc acgaaggacc aaacgtttct tctcgtgcag aaaagcaatt
     1021 tgtaccagga aatgtgatca ctgatgaacc agggatctac ttaccaggaa tcggtggagt
     1081 acgtattgag gatgacttgt tgatcacaga agatggaaat cgtgtgttga ctcgttcacc
     1141 aaaagaattg atcatcttat agtttcatca atagaagaag taagcgtaaa aatcagtgtt
     1201 cacagacttt gttatagaaa atcactcgat ttaatgatac actatagaag aacttttaag
     1261 ctgtaagaga taataaagtt gggtgttttc tccaattcat agcagtttgc agctgatcgg
     1321 cggcagtttt cttaccacgt gatcactatg ccgcatcata gagaattcgg atgtatctcg
     1381 tgcttaggca aagggaggaa taaataaatg gcagatgaaa aaaatttgat tttaaacgca
     1441 aaccaagatt taggagagat cgtgatcgct cctgaagtca tcgaagtaat tatcgggatt
     1501 gcagcttcta aagtagaagg cgtatacgga atgcgcggaa cttttgccag caatgtcact
     1561 gaattattag gacgtgcagc tcacggaaaa ggtgtttact tagcaaacga ggaagatggc
     1621 ttgaaagtag atctttactg ttatctagaa tatggtgttt cagttcctaa agtagcaatg
     1681 gaaatgcagg aacgggtcag ccagcaagtc cttttcatga cggatatcga tttatctgaa
     1741 gtcaatatcc atgtagtagc tgttgttcct gaaaaattag aacaaccaac aatcgaagaa
     1801 ctttttgaag acgaagagga agagaatgaa taaagaatta tcaagacacg agattcggga
     1861 aatggcattg caggctttat ttccattaga cttcaatgca gacctaacaa aagaagatgc
     1921 gattttcaac gcaatcgaat tagaccaccg cgacatgatc aacgaagatg aatcagagtt
     1981 tgttcctgtt tatcttgata cgctagttgg cggtgtctgt gcaaaaaaag atgaattgga
     2041 taaagtgatt gaaaaacatt taaaaaacaa ttggcacatc aatcggatct caaaaatgga
     2101 tttggtgatc ttgcgtatcg cgatttttga aatgacttat gtgacagatg taccagcggc
     2161 tgttgcttta aatgaagcaa tcgagttggc aaaaacattt agtgatgacc gttcacgtaa
     2221 attcgtcaac ggtgttttat ccaatgtatt gaaagaatta gaagctgggg cgtaagtcct
     2281 agcttttttc tatgaatcat cataaacctg ttataaatcg ggaaaattct atggtagaat
     2341 gaaaacacaa aaaatatctg ggagtggtta gatggcagaa ttgattaacg gaaaagaatt
     2401 agctgaaaaa atgcaggcag agattgctga aaaaatccaa aaattgaaag ataatggtat
     2461 ccatcccgga ttagtcgttt tattggtagg ggaaaatcca gccagccaaa tctatgtaag
     2521 aaataaagaa cgtgtagcaa aagaaatcgg aatccattca ttggtagagc gttatcctga
     2581 gacgatttct gaagacgaac tacttgcaga aattgaaaaa tacaatcaag atcctagttt
     2641 tcatggtata ttggtccaat taccattgcc aaagcatata gatgaagaaa agatcctgtt
     2701 agctatccgc cctgaaaaag acgtagacgg ttttcatccg atgaatttag gcagactcct
     2761 tgcgggtaaa ccggacaaga ttccttgtac tccatacggc atcatgaaaa tgtttgaagc
     2821 ttattctatc gatccggcgg gtaaacgagc agtagttatc ggacgaagca atatcgtcgg
     2881 taaaccgatg gctcagctac tcttgatggc agatgcaact gttactgttg ctcattctaa
     2941 aaccgaaaat ctggctgaac tggcacaaga agcagatatt ttagtcgtag caataggacg
     3001 tggacatttt gtcacaaaag aattcgtaaa accaggtgct gtagtgatag atgtagggat
     3061 gaatcgtgat gctaacggta agctgatcgg tgatgtgaaa tttgatgaag tggagcctat
     3121 tgcaggctgg atcactcctg tgccaaaggg tgtagggcca atgactatca cgatgctgat
     3181 gtatcaaacc gtaaaatctg ccgaagcttt tggagcaggt gaatagatgg cacaagaata
     3241 tttaactgtc actacattaa cgaagtattt gaaaagaaaa tttgatgccg atccttattt
     3301 agaacgcgta tatttaacag gcgaaatatc gaatttccgt ttacgtgcca atgcccatca
     3361 atatttcagc ttaaaagatg accatgcaaa aatatctgct attatgttca aaggagcatt
     3421 ccaaaaatta cgattccagc caaaagaagg aatgaaagtc cttgtcgttg ggcgtatttc
     3481 attatatgaa gcgggaggtt cttatcaaat ctatgtagag cacatggagc ctgatggaat
     3541 aggtgcttta tatcaagaat tggaagaacg aaaagaaaag ctgatgaagg aaggcctttt
     3601 tcaagggcct aaaaaaatgc tgccacgttt cccaaagcga atcgcggtcc ttaccagtcc
     3661 aagcggagcg gttatccgcg atatcatcac gacggtgaaa agaagatatc caattgtcca
     3721 attggttttg ttcccaacag ttgtacaagg aaaccaagca gcggacaatg ttgtcaggaa
     3781 tatccagaga gtagaagaga tgggcaattt cgatacaatg atcatcggtc gtgggggtgg
     3841 ttcgattgag gatttatggc cgtttaatga agagcgggtt gctcgggcga tttatcaagc
     3901 taatacgccg gtgatttcat ctgtaggaca tgaaacagat accacgatcg ctgatttagt
     3961 agcagatgtt cgggctgcca ctccaacagc agctgcagaa ttagctgttc ctgttttgtc
     4021 agaagagttg atgcgcattc aagaacggca agctagattg cagcaggcgt ttgtacgcca
     4081 gatccagcgc aaacaagaac ggttcgagcg tgctcgacgt tcctatgtat ttcggcagcc
     4141 tgaaagattg tatgaaggtc agaccatcaa attagaccag ttgaaacagc gattatatca
     4201 agctacacag caaatttatc atgcgaaaga aaaacaaacg atcgcattaa gccaccaatt
     4261 ggaacaagtg gctccgcttt atcgagttaa agcagctcgc caagaaactg cttatctaga
     4321 aaaacgctta gaagagaaaa tccaacaata tatgaaacaa cagcagcagc gttttgctca
     4381 agctgttcaa tctcttgatt tgttgagtcc attgaaaatc atgggaagag gctacagcta
     4441 tacgacgtta aatgatcaag tagtaaaaag tgtcaccgag attcatcaag gggatttgct
     4501 gacgatccat tatcaagatg gaatcgttaa aggacaagta caagagatag acaaaggaga
     4561 ataaaaatat ggaaaatcca acttttgaag agtcactgca agaattagaa aaaattgtca
     4621 tgcagttaga acaaggagac gttccattag aatcagctct agattcgttt aaacgaggaa
     4681 tggaattaag caaacattgc caagatacat tagctaaagc agaagagacc ttgacgaaaa
     4741 tgatgacaga atcaaatgaa gaagttgatt ttgacggaaa cgaggaaagc tgagatgaga
     4801 ttaactgact tttcagctat tcatctacct gctgtagaaa aagaaatctt gtctttttta
     4861 gatgagcata caacggatag aggactctat gatgcgatga gttattcagt gaaagcaggc
     4921 gggaaaagaa tacgtccctt attactttta acggccgttg cttcctttga tgagcctatt
     4981 gatgttcccg tctatcaagt agcagctgct ttagaaatgg tgcatacgta ttccttgatc
     5041 cacgatgatt tgcctgcgat ggacaatgat gatcttcgta gaggaaaacc taccaatcat
     5101 aaagtattcg gcgaagcatt agctatattg gccggagatg gtttgcttac aggagcattc
     5161 cagctaatca gtatggcaca cttaggtaat tctcctaagc ttctgctgct tcagcaatta
     5221 gctgtttgtg cgggatcaca aggtatggtt gctgggcaag ctgcagatat cgagggcgaa
     5281 tcgaaaaagc tttctttaga agaattagca tttattcatg aaagaaagac agggcatttg
     5341 attcgttatg ccttgctggc tggtggcata ttagcgaagc aacctgaaga aatcttattg
     5401 ctacttcaac gattagccga acatttaggt ttagcttttc agataagaga tgatctactc
     5461 gatgtgattg gtacaacgaa aacattaggg aaaacagctg gtaaagatga acgtatggaa
     5521 aaaaatactt acccgcgttt attaggccta gaaaagacac gtgaggcgtt ggagattgag
     5581 ctgttatccg ccaacaagat catagacaaa ttagaagagg acgttttttc ttttgatggc
     5641 gggctgatgc gccagatgat caagcaattt gatgtggaga aatgagggaa agaatggaaa
     5701 aagaacgcgt agatgtatta gcggtcaaac aaggattatt tgaaacaaga gaacaagcca
     5761 aacgttcagt gatggctggt ttgatttaca acgaaaaaaa cgagcggttt gataaaccgg
     5821 gagaaaaaat tccagtgagt agtgaattaa gagtcaaagg taaaaaactt ccttatgttt
     5881 ctcgaggggg attaaaatta gaaaaagcac tcaaagcatt tgatctatct gttgaaggaa
     5941 aaacattgtt agatattggt gcatccactg gcggatttac tgatgcagct ttgcaaaatg
     6001 gcgcaaaaat gagttatgct ttagacgttg gctacaatca gctagcttgg aaaataagac
     6061 aagatcctag agtcgtcgta atggaaagag tgaattttcg ttatgcaaaa cccgaagact
     6121 ttaccttagg aattccagaa gttgctgtta tcgatgtttc ttttatttca ctaaaactga
     6181 tgctgcctcc attacatgct attttaaaag aagagggaga agtgattgct ttaatcaaac
     6241 cccaattcga agcaggcaga gaagctgtag ggaaaaacgg aattgttcgt gaccctcaga
     6301 cccatcaaaa agttttagaa gacattttgt catttgcggc acaaggtgga tatgatgtgc
     6361 tggaattaag ttattctccg atcacggggg gagaaggaaa tatcgagttc ttggctcact
     6421 tgaggaaagt acccgaaagc ggaacaatca attcagctat taatatggca gaagtggttt
     6481 caaatgcaca cgaacagttt gaccataaat aaattgtaac tgtgaaaatc aagtgagaag
     6541 tatgcggatt cttctttatt ataccaagga aataagctat cattgattaa gaagaatatg
     6601 ctaaggagcg aagacgtaat gagaaaaaaa gatcggcatc gtttgattac tcgattgttg
     6661 agtgagcaag atatccgaaa gcaggaagaa tttgttgaaa tcctgaaaag caaaggaata
     6721 tctgttactc aagctacgat ttccagagat ataaaggaac tgaaactgat caaggtaccg
     6781 gcttcagatg gcggctaccg ttatagcata ccagctgaaa caaacgaaga tgtaaatact
     6841 aaattggaaa aactattaaa agacgctttc gtggcagttg accaaatgga aaaatttgtt
     6901 attttgaaaa cattgccggg aaatgcttcg gcagcagcaa atttgattga taaacgttac
     6961 aagaaagaat tattttcgat tatcaatgat gacgataatg ttttgatgat tacacgaact
     7021 gaagaccagg cagttttatt gaagaaagac ttcctgcatt acctttaagt tgaggagcga
     7081 atgtgatgct acaagaaatc agtattacta actttgcgat tattccggaa ttgcggcttt
     7141 cttttcacga aggaatgacc gcgctgaccg gagagactgg tgcgggtaaa tccattatta
     7201 tcgatgcttt aggtctgtta gcaggaggaa gaggttcaag cgattatata cgtcaaggag
     7261 cagaaaaatg tgtgcttgaa gggttgtttg aactaccaaa acaagaagga ttctctgaac
     7321 tgatggttga attagggatc gaaacagatg aggacaatct gattgttcga cgggatatgt
     7381 ccttaactgg aaaaaatgtt tgtcgagtga atggtcatat tatcacatta gctaatctga
     7441 gaagaatcgg cagttattta gtagatatcc aaggacaaaa cgaacatcag gaactgctcc
     7501 agcctgaatc acatcttgct ttattggatc gttttggaga tgtagctttc caacagaaga
     7561 aaaagagtta tcagcaagaa tatatctctt atcgtgagct ggaaaaaagg gtacgaaaag
     7621 tgcagcaaaa tgaaaaatcc tatgttcaga gaatagatat gctccatttc cagcaagaag
     7681 aaatagctgc tgctgatttg caagtcggag aagaagagaa attaaaagaa gaaagagaaa
     7741 aacttagcaa ttatcaaaaa attgctgatg gattagctgc aggttacgga gcactgacga
     7801 ataatgaaca aaacagtgta gatggtgttg gcttggccgt ttcagaactg caagggatcg
     7861 cccatctaga tgtggagtat gaagcaattt atgaaaatat ccaaagtgct tactatttgc
     7921 tgcaagatgc aatcggcgat atgagtcgtc agattgattt attggagtta gatgagagtc
     7981 gtttagaaga agttacgcaa cgtttagaat taatccgaca gttgaaacgt aaatacggcg
     8041 aatccattga gtcaatattg gcttactatg acgaaatcac cgaagagcta gcttcttctg
     8101 atttttcaga aggtcaattg gacaaaatga aagaggaact agagcaaaaa gagcttctac
     8161 ttcagcaaca agccgcagat cttcatgaag cgcgtaaaaa aatcgcaaaa gaattggaaa
     8221 aatccattct gcatgaattg aaaagtctgt atatggaaaa cactgagttt gaggtacgtt
     8281 tcttaaaaga agaaaataga caattgaatc atgatggatt tgaccaaatc gaattttaca
     8341 ttacgaccaa tccaggagag ccactgaagc ctttggtgaa agtcgcttct ggtggcgaac
     8401 tgtctcggat gttgcttgct ttgaaaacta ttttttcttc tgagcaaggt gtgacaagta
     8461 ttatttttga tgaagtggat acaggtgtga gcggaagagt tgcacaggcc atcgcagata
     8521 aaatttctca aatatcgaaa tactctcaag ttttgtgcat cactcatctg cctcaagttg
     8581 ctgcagtcgc cgactatcaa tattatattg tgaaagcagt gattgatgga cgtacgcaaa
     8641 cttctgtttc agagttgaaa acaaaagaaa gagaagaaga aattgcacgt atgctggctg
     8701 gaagtgagat tacaaaactc acactcgaac atgcaaaaga actattgaaa ctcgcaaaaa
     8761 ggacctgagc cacctcgcag tggttcaggt ccttttcagc agctgatagc tatattttat
     8821 ttttacatga cactcattac agcagtcaat acaacagatc caatcgttaa aatcagcatt
     8881 gtccaaatga caaattttgt tactttagca aaagtacttg tttgtttttt ttcacgcatt
     8941 gttttcaacc tcgtcattaa ttagttgatt caagtgtaca atcttttttc catttccaca
     9001 agagggcttt tttataaaaa cttccctttt tttaaataat aggtagttac gatacaaata
     9061 aataatgtta atagaactag ccatataaag gcatcatccc tttcagcaat aggtaactta
     9121 atgttcattc catagatact gccgacgatt gtcggtatag ttaaaataat cgttaaagaa
     9181 gttaaaattt tcataatatt attcagatta ttcgatacga ttgctgaaaa agtctgattc
     9241 atttgttcta ctagttttaa ttgaatgcga gaagtagtca ttgcctgctc tgtttccacc
     9301 aatacatcac gtaaatgatt tttcaaagca tgattttctt ggaaaagttt attttgcgct
     9361 agttctttca atgcatctaa attagcagaa gtcgcttctc tgaaataaac gaggcttttt
     9421 tggatatcca tgatttgata aagttgtttg ttttcagtgg atacttgaag tttggcttcc
     9481 aaagtatcgc attgagattg aagcgtagct aaataactgt tgtaagagag tgtgacctgc
     9541 caaatgaatt gaaagaagat attgagatta ggcgaaatat cactttttgg aaaggtctgg
     9601 ctaaagactt tctttaaaaa cagtggttca tgattcgtaa ttgtgataag cttctttttg
     9661 ggcgtcaaaa taatagagag cgggtatgta tccacttgaa aataaccgct aggacttgtt
     9721 ttagcaaaag gatattgtaa caataataac gctggctttg tcaactttga ttgattgaat
     9781 tcttctgtac gggaattttc tgcatcgtcc aatatggaag tgatgtaatc tgacggaatt
     9841 tcaaattgat gtgtcagctg atgaatctct tcttgattag gacgttctac acaataccag
     9901 atcgtttggt cagtttcctt tccggtatta cgcagtttct cattatctaa tgtaaaatat
     9961 ttgatcatga ttttcctcct gttgcctgtt tcttttatta taacggatag ggaattggaa
    10021 tacatggaat gtgtttgtaa gatatagaat ataactgcat aaatttaaat aaaatgaaac
    10081 agttgtgtaa agtatataca gtatacttga agcaacgata aaaaaggagt ttacgttcat
    10141 gggcacattc acaccactta tcttgttttg gtatatttac ccggtaatcg ttttgtttgg
    10201 ttgccaattt cttgtaaaat tattttcgtt aaatcgtcgt tttaaaataa aagcccctga
    10261 tttggcgatt ccttttttgt ggggcggtat gcatgcattg tctagaaata cagggacaat
    10321 ttctatctta ccgtttttct ttatttctgt tttgctaatg ggaatttgta ttgctgtttt
    10381 ccaagcatat tattatgaag aaattattta tccgcgttat ttcaagatga cttggcgttt
    10441 ggtttttctg ttgacaatcg tcttgtacgc tgtcttgatc attgtgaaca tactttctta
    10501 cctatgaaaa aaatagaaaa gctgtaaaaa gtcttttaaa aggctttttg cagcttgatt
    10561 tttaaaaaaa tgtttatgaa taaaaaaagt tgttcccgga tttcccagaa aaggtggtag
    10621 aaagtggggg attgtggtag actaatttta gttagtggag gaatgggggg ctttcaatgt
    10681 tgatgggtga attccaacat aatattgatg caaaaggacg tttaatcgtg ccctcaaaac
    10741 ttcgtgaaga acttggcgaa aagtttgttc tgacacgcgg attggatggc tgtcttttcg
    10801 gctatccgat gagcgaatgg gaaaatctgg aagctaaact gaacgaaatg ccgttggcta
    10861 aaaaagacgc acgtactttt gtgcgattct tctattcggc tgccactgaa tgcgaacttg
    10921 ataaacaagg acgaatcaat atacccagca cgttaagaaa ttatgcagct ttgacaaaag
    10981 gttgcgtagt catcggtgta tctaaccgaa ttgaaatttg ggatgagaca cgatggcaag
    11041 atttttctgc agcagcagaa gagaactttg acgaaattgc tgaaagtatg attgatttcg
    11101 gactataaga ataggaagag gctgactaat gactgaaaca tttcaacact atacagtcat
    11161 gttgaaagaa acggtagatg gattgaacat caaaccggat ggcgtttatg tagactgtac
    11221 actcggcggt gccggacata gtgaatattt attaagccaa ctaagttcta aagggcatct
    11281 gtatgcgttt gaccaagatc aaaaagcaat cgatcacgcc aagctgcgtt tagcttctta
    11341 tgtcgaacaa ggtatggtca catttatcaa agcgaacttc agagaattag aagaacgctt
    11401 gagtgagcat gtagataagg tagacggcat tttgtatgat ctaggggttt cctctcccca
    11461 gctagatgaa gcagaacgtg gatttagtta tcatcaagat gcaccgttgg atatgcgcat
    11521 ggatcagtca gctcctttat ccgcttatca cgtaattaat gaatattcct accatgaatt
    11581 agtaaagatt ttcttccgct atggcgagga gaaattttcc aaacaaattg ctcgtgaaat
    11641 cgaacgagta cgaaaaacaa aaccaatcca aacaactggt gagcttgtcg aaatcattaa
    11701 acaagtcatc ccagctcccg caagaagaaa aggcgggcat cctgcaaaaa gaatttttca
    11761 agctgtgcgg attgcagtaa atgacgaact cggtgccgaa gaggcctctt tagaacaggc
    11821 aatccggtta ttgaaagtca atggaagaat cagcgtaatc acattccatt cattggaaga
    11881 cagaattgtc aaaagtatgt ttaaagaata tagtacggta caagatctac caccgggact
    11941 tcctgtcata cctgacgaat tccaaccaga actgaaagtc attactcgta aaccaatcct
    12001 tccttcagag gaagagctaa cagaaaacaa tcgatcacgc agtgcaaagt tacgtattgc
    12061 agaaaaaata agaatgaaag aggagtagaa tgatggcaga attaaagaaa atgcaagatt
    12121 acgaatatga tttacctgaa ttggtggatc agccggaaca acaaatgcct gattcttctt
    12181 cgaatcaaga aatcattctt ccacaatcac cggcaaaacg attaaagcag atttctgctt
    12241 tggaaaaaat tgctgtggca agcgtggcga ttgctattgt tgctttatgt gttttaacag
    12301 ttatgctgcg cacaaatatc agcggagctg aaaaagaaat cacgtcaata caaacagaaa
    12361 tcaatgataa aaagcaagaa aaaacgagtt tagaacaaga aaaaaacgaa ctttctcgta
    12421 ctgaacggat taaacaaatc gcagaagaaa aaggattgtc tattaatgac gacaatttaa
    12481 ggaaagtgaa gtaaatgagt cttaaaaata aaattcggcg gtttatggaa aagaaaaatc
    12541 taaatccgat gaacaatcgc aaaaaagtag gtatcatttt atttgctacg agtattggat
    12601 tgttcttttt atttgccgtc cgtttctcgt atatcgttat tggaggtcat gttgctggta
    12661 cctcattagc tgaaaaaaca aaacagttgt accaaggaag tgaagtagta aaagcaaaaa
    12721 gaggaacgat ttatgatcgt aacggtgtgg cgctcgcaga agatgcctcc tcttattcaa
    12781 ttaaagcgat actctcaaaa acatatacct ctggggataa aaaactgtat gttgaagaaa
    12841 agaattttga taaaatagca gaaatcctgc ataagaatct ttctatagac aaaaaagatg
    12901 cactgaatat tttagaggac ggcgcaaaaa aagagctgta tcaagttgaa tttggtagct
    12961 atgggaaaaa tatctcccaa gaaaccaagc aaaacatcga agcggacatg aaaaaagaag
    13021 gtgtcgctgg tctttatttt gtcgaccatc aggctcggat gtatccaaat ggcgtctttt
    13081 cttctcattt tattggatac gcagttccag acaaagatga gaatggctta gttggtaaac
    13141 taggtttgga gtctgcttac aatgatatct tgagcggtaa agatggtaag attatttatc
    13201 aaaaagataa ttttcaaaat cctctgccag gtacagtggc agaagaagaa aaagctgtcg
    13261 acggacaaga tatctacacg actttagaca gcagactaca aagttattta gaaacactga
    13321 tggatcaagt aaatgaagaa tatcagccag aagaattgac agcagtcctg atgaaagcaa
    13381 aaaccggaga aatcttggca atgggacaac gacctacttt caatcctgaa acaatggaag
    13441 gattgactgg aaaagatgct atctggcgta atttcttggt acaagatagt tatgaaccag
    13501 gatcaaccat gaaagttttc actactgcag ctgctatcga agaaggagaa ttcaacgaga
    13561 atgaaacctt ccaatctgga aaaatccaag tagaagatgc tacgatcaat gaccatgact
    13621 ttggtgaaaa aggtgtgctg accatgcgtc aagctctttc atggtcaagt aacgtcggga
    13681 tggtcatact ggaacagcga ttaggcggac gatggtataa ctatttacaa aaactgggat
    13741 ttggacaaag tactcattct ggattagatg atgaagtaaa cggtgcttta cctacattaa
    13801 atattgtcga ccgagcaatg agtgcttatg gacaagcggt aggtgtgacg aatttccaaa
    13861 tgatgaaagc tttcacttct attgcgaata acggtacaat gattcaacct cgatatatca
    13921 gcaaagtggt ggatccccaa actggagaag agcgaacaac tcaaacagaa gttctagggc
    13981 aacctttttc aaaagaaaca acagaaaaag tccgtgaata tatgagagat gttgtcgaaa
    14041 gcgaaaacta cggtattgct tatggtgtat atagtgtacc tggatacaat gtatcggcaa
    14101 aaaccggaac agcccaaatc gcttctgata cagggggata tcaaacagga gatacagcct
    14161 acctgtattc gattgtggag atggttcctt ctgaagatcc agactatgtc ttgtatctaa
    14221 caatgaaaca ccctaagaca tatgatcgaa tggcattggc taaaatcgca aatccattga
    14281 tgaaacgggc aatggatttt aaagaaactg aagaagattc agatacagaa acaaaaacag
    14341 aaaaagtatc cgtagccgat tatcgtaatc ttgaagcgga cgttgcagca gctgatgctc
    14401 aaaaaagtgg actgcaacct gtagtgatcg gtaatggtaa aaaagtacaa aaacaatcta
    14461 ctgccaacgg tgatcagttg atctctggag aaaaactgat cctatatact ggtggtgata
    14521 agctgatgcc tgacgtaaca ggatggtcaa aagcagatat catgaagctg gggaaaatcc
    14581 tcggtattga agttagtttt gatggagatg gttattgtgt caaacaagaa cttgctccat
    14641 atgaaaaaat cactgaagac aaacttagtt ttactttaga agaataagaa gagaaatagg
    14701 agagaaaaga gcatggaatg gacacaagca ttgattccca ttgtcagcag ttgtgcaatg
    14761 acaattgccg caatgccgct atttattggt tattttcaaa tgaaaaagca aggtcaggcg
    14821 attcgtgagg agggaccaaa gtggcacaat agcaaagccg gaactcctac aatgggcggc
    14881 ttagtgtttc tgatcggctc tattttgaca ggaatttggg ttggagcttg gcaaaaacag
    14941 ctaactccta ctcttttcat cttgcttttt gtattagcgt tatacggagt aatcggcttt
    15001 cttgatgatt ttataaaaat attcaagaaa agaaacatgg gactgaactc gaagcagaaa
    15061 ttgattggac agattctagg gggaatcatc ttttatcttg tttaccgttc tgaaggttat
    15121 ccaggtgtat tgaatttctt cggactagat ctacctttag gaatcattta tggtattttc
    15181 gctctcttct ggcttgttgg attttcaaat gcagtaaatc tgacagatgg catcgatgga
    15241 ttagttgctg gcttaggaag tatctctttt gcagcttacg gtctaattgc ttggcatcag
    15301 catcagtatg atgtattaat catttgctta agtgttttag gaggtttact gggtttcttc
    15361 gtctacaaca gaaaacctgc caagattttt atgggagatg tcggttcatt agcgttgggc
    15421 ggacttttag cggcaatttc tataatgcta aaccaagaat ggacattgct tttgattggt
    15481 ttgatctatg ttatggaaac agcaagtgtg atgcttcaag ttacttcctt taagcttaca
    15541 ggaaaacgaa tttttaaaat gtctccaatt catcatcact ttgaaatgtg cggatggtcg
    15601 gagtggaaga ttgatacagt tttttggttg atcagcattg tgacttcgtt gatcacatta
    15661 tggatcgttt ggtaggagat gacgggaaat gaaaaaaata tcaacatatg aaaataagaa
    15721 agtgcttgtc ttaggactcg caaaaagcgg agtaagtgcg gccaaattat tacatgaatt
    15781 gggcgcactt gtcaccgtta atgatggaaa accttttgac gaaaatccgg aagcacaaga
    15841 gctgctttct ttagggataa aagtaataac aggtagtcat ccaatcgaat tgttggatga
    15901 agaattttca ttgatggtca aaaatccagg gattccctac agtcatcctt tagtagcaaa
    15961 agcccaagaa atgggtattc cggtaattac ggaagttgag ctagcttacg aagtagcgga
    16021 atgcccaatt attgggatta caggaacgaa cggaaaaaca acgacaacaa cgatgacagg
    16081 actactactg aatgcaggag cagatcaagg aattgcacgt ttagcgggta atattgggta
    16141 tccagcaagt ggtgtagcgc aagaagcaaa atcagaagat aaaattgtga tggaattgtc
    16201 tagcttccaa ctcatgggaa tcacagattt ccgccctcat atagcggtga ttaccaatat
    16261 ctatgaagca catattgatt atcatggtac aagaaaagaa tatgtcaaag ctaaatggaa
    16321 ccttcaaaaa aacatgacag aaaaagatta tctgatcctt aactggaatc agtcagaact
    16381 acaagaatta gcgcaaagaa caaaagcacg cgtactgcct ttctcgacaa aagaagtgtt
    16441 ggaagacggt gtgtatgctg acgattactc aatatactat aaaaaagaaa aaataatgga
    16501 aatatctgaa cttggcgtac caggtaagca taatgtagaa aatgcactag ctgctatttc
    16561 tgtagcaaaa ttgtatggta tatcaaatga agctatacga gaaacgttgc attttttcca
    16621 tggcgtacca catcgtacgc aatatgtagg agaaatccaa ggcagaaaat tttataatga
    16681 ttcaaaagca accaatattt tagcgactaa aatggctcta agtggatttg aaacgtctaa
    16741 ggtcgtgtta ttggctggcg gattagacag aggaaataca tttgatgaat taattccttc
    16801 attaaaagga atcaaagcaa tggtcgtatt tggccaaaca aaagaaaagt tgatggatgc
    16861 tggaaaaaaa gcaggcatcg agacaatagt aacagccgat tctgtagaac aagcagttcc
    16921 tttagcatta gaaaacagta cagatggtga tgtagtttta ttatcaccag cgaatgccag
    16981 ctgggatcaa tacccaaatt ttgaaactag aggaaacaga ttcatggaag ctgtgaaccg
    17041 attaaaatag aaaaagtaga agcgagcgat aaaaaatgaa aattttggtt acaggcggag
    17101 gaacaggggg acatatttat ccagctcttg cctttgtcaa ttatgtaaag actcaagaac
    17161 cgaatgctga attcatgtat gtgggagcaa aacgaggtct agaaaacaaa atcgtccctg
    17221 atacaggaat gcctttccat accttggaga ttcaaggatt taaacgaaaa atttccatgc
    17281 ataacatcaa gacggtccga ttgtttctta agagtatccg tcaagcaaaa aaaatcctca
    17341 gtgattttca accagatatc gttatcggta ctggaggata tgtttccgga gcggtagtgt
    17401 acgctgcagc caaaatgggt attccaacag ttatccatga acaaaacagt gtaccaggtg
    17461 ttaccaataa atttttaagc cgatatgtgg atcggatcgc tctttcattt aaagatgcgg
    17521 cttccttttt tcctgaaaac aaagcagttc ttgtaggtaa tcctcgagca caagaagtag
    17581 cagatactaa aaaatcagat attttgaaaa catttgattt ggatccagaa aagaaaacag
    17641 tcttgatttt tggcggtagt caaggagcac ttaaaatcaa tcaagcagta tcagtttttt
    17701 taagtgaata tattccttct tcttaccaag ttttgtatgc ttcaggagat agatattatg
    17761 aagagatcct aaataaaata aatcctgaaa tacaaaatat tagtgtccag ccttatatca
    17821 aaaatatggc agaggtcatg gcttccagtg atctgctggt ggggcgtgct ggtgcaactt
    17881 cgatcgcaga attcacagct ctggggttac cggcagtgtt ggttcccagc ccatatgtta
    17941 cgaatgatca tcagactaaa aatgcaatga gtcttgttca cgcaggagca gcaaaaatga
    18001 ttgcagataa tgaactaaca ggtgaatcac taagtcagac agtcaacgaa atcatgggtg
    18061 atgaagaatt gcaaaagcaa atgtgccgag cttctaaaga acaaggaatc cctgatgctt
    18121 caaaacgtct ttatgactta gtaaaacaaa taatcaaaaa ataaaggcgg tggtcttagt
    18181 gagtaagaaa aaagaaccaa aaaaattgtc tcatccgtct tctgatgaaa acaatttgac
    18241 tccttggcaa aaggctaacc gaaaatatct ggcagaacaa gagatgaaaa accaagagcc
    18301 aaaaaaagaa gacataacat tagatacacc cctttcagat tctgaagaag aaaaaacggt
    18361 tcaagaggaa cagcaagaag aaagccagtc cgagaaaaaa atcgaatttt ttgaagagat
    18421 caagcaaaag aaaaacggtg gaccatataa cggttctttt ttgaaccggc tgcccaattt
    18481 aaaaagtcaa cggcacaaag tactatttcg tcggttagct ttgatcatca ctgtattggg
    18541 tataccgctg atttttttga tctattatgt ttctccttat agcaaattac aagcagttgc
    18601 agtatcaggc aataagacag tcaacagcca agaaatcatc tctgatacaa aattgtcatt
    18661 aggagaaaat gtttggggac agtattttca tcgatctact tatatcgatc gccttaaaaa
    18721 agcacagcca agaatcgaaa cagcaaatat acatttcaaa gggatgaatg aattcgattt
    18781 ggatgtaaca gaatataaag agattgcttt gatcgcaaaa aacaatcaat actacccagt
    18841 gattgaaaat ggaacagtat tagatgaaaa agtagcaaat cctacaaaaa atctccctat
    18901 cttggaagag ttcaaagact ctgcaaaaat caaagaatta acaaagcaat acaatcagtt
    18961 atcatcagaa ttacaaaaag caatttctga aatcaagtac acgccaagag caagcaataa
    19021 aaatctgatc caattgaata tgaatgacgg caatcaagtt attgtaaata tcaataatct
    19081 tgcgaaccaa atgaaatatt attcgcaagt agccaaagat atggatgaaa aaggtgtgat
    19141 cgacatggaa gttggtatct tctcgcatcc ttacggtagc actcaagaaa cggaagaatc
    19201 gggccaatcg gaagaaacaa ctgaaagtga agaaaatgcg gatcaaacaa acgaatcaag
    19261 tgaagaggca gaaacgcaaa aagcacaaac acctggatcg tctagcacaa acggatcatc
    19321 tgattcaaat gattcaagtg aaacaagtca aatagaagat aatccaagta caactccgtc
    19381 aagtttaaat gaaaattgat aaaacaactt taaaaagtaa gaatgtactt tctaaaaacc
    19441 agtaatttat ggtagaattg gaagcagtga atatatctat taataagtat attttaaaac
    19501 ggacgctagt tgttcgcttg tatatggaat agtaagtagg agggaatccc attcatggca
    19561 aaaacaggaa tgtatgtagg ccttgatatt ggaacgacat ctgttaaagt tgtcgtggct
    19621 gaatatatcg acagccaaat gaatattatt ggagtaggaa acgcaaaatc agaagggatt
    19681 aaccgaggca ttatcgttga tatcgataaa acggtccaag cgatacaacg agcagtacga
    19741 caagcagaag aaaaagcagg tatccagatc aaaggcgtaa gtgtcggttt gccagcaaac
    19801 atgcttgaag tagaaaattg ccagggaatg attgcagtta acggagattc aaaggaaatc
    19861 accgatgaag atgtcagaaa tgtggcttca gctgcccttg ttcgttcaat acctcctgaa
    19921 cgtcaaatcg tgtcaatatt gccacaagat tttactgtcg atgggttcga gggaatcaaa
    19981 gatcctcgtg gaatgatcgg cgtaagatta gaaatgtacg gtctgttgtt tacaggacct
    20041 aaaacgatca tccataacat acgtaaatgc gtggaaaatg ccggattaat cgtcaacgaa
    20101 atggtgatta ctcctttagc gctgactgaa tcaattcttt ctgacggaga aaaagatttt
    20161 ggtacgatcg tcattgatat gggtggcggc caaacaacaa cggctgttat gcatgataag
    20221 caattgaagt ttaccaatct tgaccaagaa ggtggcgaat ttgtcactaa agatatctct
    20281 attgtattaa atacgtcatt taacaatgca gaagcgttga aaataaacta cggggatgca
    20341 tacccagaac ggacatcacc agatgaagaa tttccagtag atgtgattgg tcagtcagaa
    20401 ccagtgaaag tcgatgaacg ctacttgtca gaaattattt cagctcgaat ggaacagatt
    20461 ttcaacaaag caaaagatgc attggaccaa atcgaagcat tagagttgcc aggtggcgtc
    20521 gtattgacag gcggagctgc tagtcttcct ggtgttgtgg acttggcaca agaaatcttc
    20581 ggcgtaaatg taaaattgta tgttccaaat cacatggggc tgagaaaccc ggtatttaca
    20641 aatgtaataa gtatcgtgga ttattcagca aacttgagtg aagtgtatca attggcaaaa
    20701 attgctgtta cgggtgaaac ctcagcagct cgtcaaatgg tagttgaaca agaaacaaca
    20761 aacacatatg agagctatga agcacctgaa gaaacaatct acgatgagcc ggaaccaaaa
    20821 gagtccggag aaaatgtaaa aaataaaatc aagggtttct ttacaaatat ttttgattaa
    20881 ttcatcctgg gaggaataag atatggaatt ctcaattgat aataatatca atgacggcgc
    20941 agtaatcaaa gtcatcggag tcggtggtgg cggtggaaat gctgtaaacc gaatgattga
    21001 agaaaacgtt aaaggtgttg aattcattac agccaacaca gacgtgcaag cattaaaaaa
    21061 ttcaaaagct gaaacagtta tccaattagg ccccaaatat actcgtggtt taggtgctgg
    21121 ttctcagcca gaagttggac aaaaagcggc agaagaaagt gaacaatcct tacgcgaagc
    21181 tttagacggt gcagatatga ttttcatcac tgcaggaatg ggtggaggaa ccggtacagg
    21241 tgctgcacca atcgttgcag gtatcgcgaa agaattgggc gcattgactg ttggtgtcgt
    21301 gacacgtcca ttcacttttg aaggaccgaa acgtggccgt tttgctgcag aaggtatcgc
    21361 tcgtttgaaa gaaaatgtgg atacattatt aattatctca aataaccgtt tattagaagt
    21421 tgtagataaa aagacaccga tgcttgaagc tttccgtgaa gcagataatg ttttacgaca
    21481 aggtgtacaa ggtatctctg atttgatcac agcgccaggt tacgttaacc ttgactttgc
    21541 tgacgtgaaa acagtgatgg aaaaccaagg tacagcattg atggggatcg gtgtggctag
    21601 tggagaagat cgcgtagtag aagcaacgaa aaaagcaatc tcctctccat tgcttgaaac
    21661 atctattgat ggagctgaac aagtacttct taacatcaca ggcggtttgg atatgacatt
    21721 gttcgaagca caagatgctt cagatatcgt agcaaatgca gcaactggcg atgtaaatat
    21781 cattctaggt acatctatca atgaagaaat gggcgatgaa atccgtgtga cggtcatcgc
    21841 aacaggtatc gatgaatcaa aaaaggaacg caagtctagc cgaccagcta gacaagcaca
    21901 aatgcaatca cctgctcaaa agactgtatt agatatggat caagctaaac caacttcttc
    21961 agaagaagaa aacagttttg gcgattggga tatcagacgt gaacaaaatg ttcgtcctag
    22021 agttgatgat tccaattttg acaatatcga aaaaaaagaa tttgatacat tcaaccgcga
    22081 agaaacaaaa tctcatggcg atgatgaatt aaatacgcca ccgtttttcc gtcgtaaaaa
    22141 ataaaggaga ggaagagcac atgattgctg acaacttgca gaaaatcaag caagaaattc
    22201 aggattcgtg tgctcttgtt catcgtgatc cgaaagaagt tacattagta gctgtaacaa
    22261 aatctgttga atccgctcaa gctgaagaat tggttagagc tggcgttatg aattgtgcag
    22321 aaaaccgagt agataaatta ttagaaaaga aacaagattt atttgatttt cctgaaataa
    22381 agtggcattt aattggtaat ttacagcgca gaaaggtaaa attgattgta aatgaaattg
    22441 attactttca tgcgttggac agtttaagat tagcagaaga aatccagaag cggttagaga
    22501 aagaattatc ctgttttatt gaagtaaatg tttctggtga ggaatcaaaa catggaattt
    22561 caccagatga gcttttaccg tttgtggaat ctttagctgc ctgcacaaaa atcaaggttg
    22621 ttgggttgat gactatggcg cctaaagaag cttctgatga gcaaatccat aaagtgtttg
    22681 gtacgctgaa agaattgcgt gatcttgttc aagcaaaagg ttatgcccat gcaccatgta
    22741 gtgaattaag tatggggatg agtcaagact ttcaaattgc gattgaagaa ggtgcaacat
    22801 ttatccgtgt aggaacagcg ctattcaaag acgaataaag gaggaacaaa aatgccgctt
    22861 ttaaacagag gagcaattgc taattttttc ggattagctg atgaggaaga gtacgaatac
    22921 caagattatc ctgaaacaac aaaaaaggct gtacagccaa ctaaaaaaaa tacaacacag
    22981 aatcaatcaa ctcattctgt atctgctgcg aatactcatg aaaaacaaaa aacggcgact
    23041 tcacgtcctg taacgcatga aagtattcag ccggctgaaa agaaaaaagt aattgaacta
    23101 catcaatcac ctacaaaaac tgtagcgaaa gaaagaacag cttcaagaac ctctacacaa
    23161 cctaaagcaa atcttgctgg aaaaatcact gtaatggaac caagagctta ttctgaagct
    23221 atggcgattg ctaaacgaat cattgctgga gaagcaacct tagtgaattt tcatttagta
    23281 gaagaaaaac aagcgagaag aatcgttgat tttctaacag gaacagttta tgcactagat
    23341 ggagatatca aacgtgttgg agatgagatt tttctttgta caccgactgg gatggagatt
    23401 gacagttcaa ccgctcaatc ttttgcagat gcgaatttgt ttgatctgta agaggaggaa
    23461 ctacgattta tactattgca ctattacttc atttacttca acgggcagcc tatttctata
    23521 gcattatctt gatggtatat gcattgctct cttggtttcc aggcgggtat caatcagggc
    23581 taggacgatt attagctaag atctgcgaac cgtatatcag tttgttcgat cgtctgcctt
    23641 tgaggattgg acccttggat ttcacaattt taggggcaat cctgatcttg aacttagccg
    23701 tacaaggttt agcacagatc gttatatgga taactgtcca tttagtttat tgattgaagc
    23761 aacaaaatct ttattctcag aatagatagg aggggaaaat tttggatgca aatgtatacc
    23821 agcactttcg ggcagatgaa cgtacattta tcgattcggt aggcgattgg attgaacagg
    23881 ttcaaggaca atatgcaccc tatctgaccg aatttcttga cccaagacaa tcctatattt
    23941 tagaaacact gattcgacaa agcagtgatt tgcgtttcat gttttatggc ggatatgaac
    24001 aggcagaaag aaaaagatgt ttgattttcc ccgattatta cgaacctgta gaggaagatt
    24061 ttgaaacagc attgtatgaa atccattatc ctagcaaatt tgccagccta agtcatggga
    24121 aaatccttgg aactttagtg ggaacgggga tcaaacgctc ttactttggc gatatcatct
    24181 cggacggtga tcgctggcaa gtatttattg caaatgaggt ggatcatttt gttgctgcac
    24241 aagtaacaaa gattggaaag gttgctgtac gcttggaacc aatcaaatac acagaaatga
    24301 ttatgccgaa agatagctgg acacaagaaa gaggaacagt tagttccatg cgactagaca
    24361 gtgtgatctc tgagatttat aatatttcca gacagcggtc caagcagctg atcgaagctg
    24421 gtaaagtaaa agtgaactgg acagaaaata caagacctga ttttgtactt gaactattag
    24481 atattatttc agtcagaggt tatggcagag tccagatcca agaacttgag gggaagacga
    24541 aaaaagaaaa gtacagggta ctgttcggtg tattacgtaa ataaaataaa aaggtggttt
    24601 actcatggct ttaactccat tagatatcca aaataagaca ttcccgacaa aaatgcgggg
    24661 atataatcaa gacgaagtag atgatttctt agatttagtt gttcgtgact atgaggaatt
    24721 gactcaaaga aatcgagaat tagaaaaagc agtcaaacat tctgaagaaa aacttgagta
    24781 cttcaatgaa ttaaaagatg ctttgaacca atcaatcatc gtagctcaag atacggctga
    24841 taaagtaaaa acaagtgcaa gcaaggaatc cgaagtgatc gttacttctg cacaaaacaa
    24901 agcagatgag ttagttgcga acgctgaaaa acgtgcacat caattaacaa ctgatgcaga
    24961 agaaaaagca agaaaaatct tgacagatgc aacagaaaaa gcaagacagc ttgcgacaga
    25021 aactgaagat cttaagaaaa aaacacgagt attccatcaa cgtatcagct tgatgcttga
    25081 gtctcaatta gaacaagtga aaagtccgga atgggatgaa attttacaac cattctccag
    25141 ctacgtgact gacagccatg aagtgatcaa agaagtttta gcaaaacagc ttgacaatga
    25201 aaatgatact gatgtaaact cagacacagg agtcatagaa gcacctatga cggcatttga
    25261 tacacaggct attgatatct cgatcgtgcc tggtgaaaat gaaaacgagt agaacagaaa
    25321 agcactttgt tattcttaaa gcgagccgat gagagtggaa gttcggtaag acactgcatg
    25381 gtgaaagatc ctctacttga gacctgcttt tccgaaatta gagtaagaag cagcggctga
    25441 cctcgttatt ggtcacagag agtttgcact agatagatgc aactaaattt gggtggtacc
    25501 acggcatgtt cgtcccttgc ggctgaacat gcttttttgt gtccggaaaa caaataaagg
    25561 agtgtatggt tgaatgaaaa tgaaagaaac cttgcaatta ggaaaaacaa aattccctat
    25621 gcgtggtaat ttgccaaacc gagaaggcga gtggcaaaaa gaatgggaag aaaatcgaat
    25681 ctaccaaaaa agacaagagt tgaacgaagg aaaacctagc tttgttcttc atgatggacc
    25741 tccatatgcc aatggtaata tccatttagg acattcattg aataaaatca gtaaagacat
    25801 tatcattcgt tcaaaatcaa tgtctggcta tcgtgcacca tatgttccag gatgggatac
    25861 acatggattg ccgattgaac aagtattggc taataaaggc gtgaaacgta aagaaatgtc
    25921 catggcagaa tacttggaaa aatgtcgtga atatgcactt tcccaagtag ataagcaacg
    25981 agcagatttc aaacgcctag gagttgcagg agattgggaa catccttatg ttacattaga
    26041 tccttcttat gaagctgcac aagtacgcgt atttggtaaa atggctgaaa aaagctatat
    26101 ttacaaagga ttgaaaccaa tttactggtc tccgtcaagt gagtcttctt tagcggaagc
    26161 tgaaattgaa tataaagatg taaaatctcc atctattttt gtagctttca atgtcaaaga
    26221 cggcaaagat attcttgatg aagatacagc ttttgtcatt tggacgacaa caccatggac
    26281 attgccagca aaccaaggta ttgctgtaaa tccaaaattt acgtatgtat tggtggaagc
    26341 cgatggccgt aagtttgtcg tagcgaaaga tttgctagaa acagtccaat cagaaatcgg
    26401 ttgggaaaat gtaacagttc taaaagaatt tgctggacaa gaaatggaat atatgactgc
    26461 aagtcatcca ttctatgaac gtgaatcact tgtgatttta ggcgatcatg ttactttaga
    26521 cgctggtact ggattagtcc atactgctcc aggacatggg gaagatgact atatcgctgg
    26581 tagcaaatat aaactatctg tagtgtcacc tgtagactca aaaggattgt ttacagaaga
    26641 agcacctgga tttgaaggta tcttttatga caaagcaaat cctatgatca ctgatctatt
    26701 aaaagaaaaa ggagctttgc tgaagctaga tttctttact catagttatc ctcacgattg
    26761 gcggacgaaa aagcctgtga tctatcgggc aactccacaa tggtttgcat ctatcgataa
    26821 attccgtcag aatattttgg atgaagtaga aaaagtagag tgggttatcc catggggtaa
    26881 aacacgtttg tataatatga tccgtgaccg cggcgattgg gtaatttccc gtcagcgtgc
    26941 atggggagta ccacttccga ttttctatgc tgaaaatgga gaagcaatca tcacaccaga
    27001 aacaatcgaa catgtggcaa aattatttgc tgaacatgga tcaattatct ggtttgaaaa
    27061 agaagcgaaa gaacttcttc ctgaaggatt tacccaccca ggttctccta atggcgaatt
    27121 tacaaaagaa aaagatatca tggatgtctg gtttgattct ggttcttctc atgaagctgt
    27181 tttacgtcag cgaccagaat tatcattccc agcagatatg tatttagaag gatcagacca
    27241 atatcgtggc tggttcaact caagtatcac gactagtgtg gctatcaatg gtgtagcacc
    27301 atacaaatca gttatttctc aaggatttgc tttagatggt gaaggccgta agatgagtaa
    27361 atctttagga aacatcattg caccagaaaa agtgatcaaa caatttggtg cagatatcct
    27421 tcgcttatgg gtatctagtg tagattatga agcagatgtt cgtgtttcta tggatatctt
    27481 aagtcaagtg gcagaagtat atcgtaaaat cagaaatacg atgcgtttct tattagcgaa
    27541 tacagaagat ttcgatccta aaaaagatac tgtttcgtac aatgatttac gttctgtaga
    27601 caaatatatg accgttcgat tgaaccaagt aatcaaagaa atccgagaag aagggtacga
    27661 caaatataac ttcatgcata tttaccgtac agttatgaac ttcttgacgg ttgatctatc
    27721 gtcattctac ctggattttg ctaaagatgt agtttatatt gaagcagaag atgattatca
    27781 acgtcgttgc atgcaaactg ttttctatca aacagctgta gctttgacaa aattattgac
    27841 tcctatcatt ccgcatacag cagaagaaat ctggtcattc ctgaaagaag aagaggagta
    27901 cgttcagtta agcgagtttc ctggttatga agagtttgca aaccaagaag aattgatgga
    27961 tacctggact gctttcatgg acttccgtga taatgtctta aaagcattgg aagaagcaag
    28021 aaacagcaaa ttgattggta aatctttgga agcaaaacta actgtttatc caaaacaaca
    28081 agttcgtgaa atgttaaaag ctttggatgc agatattgca caattattga tcgtttcacc
    28141 agactacttt gaagttatgg cagcagatga acaagtgcca gataacgcta tggtatttga
    28201 tgatgttgct attacagtgg aaaaagcaga cggggaaact tgcgatcgct gtcgccaagt
    28261 tcgtaaagat gtaggagtag atgaaaaact tcctcatcta tgcggtcgtt gtgcaaaaat
    28321 cgttgaagac ttctatcctg aagctgtagc tgaaggattc gaagaaaagt aaaagggaaa
    28381 agggggtgtg acatgttctt tgtcacaccc ccttttgtta tcaatcgttt aattttccac
    28441 gttcacgata ccagttatct ggttgccaga tccattcgaa tccgtctttt tcaagtagtt
    28501 cgaaagctgc tttaggtccc attgatccag ctttgtagtt gggaaaatcc ggttgtgttt
    28561 ggtcccaagc ttttcgaatg acatccacga tatgccaaga ttgagcgact tcttcccaat
    28621 gagagaagtt cgttccatca ccattcaacg catctaatag taatttttcg taagcttctg
    28681 ggctattttc aaccatttct gcactatttc taaattccaa tttgattggt tccgtttcaa
    28741 atccttgccc tacttctttc ccattcaagg ataaagaaaa tccttcagtt ggctgaatat
    28801 agatcgttag aacattaggt ggaagtgtcg tatcgtcaca tggttcatcg acagatgttt
    28861 tgaatacatt aacaggaact tgtttgaata cgatgttgat ccgagtccct ttttcagtca
    28921 aacgtttgcc tgtacgtaca tagaaaggaa cacctgacca acggaagtta tcgatagtga
    28981 atttgcctgc gacgaatgtt tcagtctctg attgagcatc cactttgtct tcttcgcgat
    29041 agcccttgaa ttgtacacca tccaattcac cttgagcata ttgcccgcga acgaagtttt
    29101 ctaacacttc ttcttcgtta taaatgcgga tagctttcaa tgctttgatc ttttctgtac
    29161 ggatttcttt ttcggaaaat gctactggcg gttccattgc aagtaatgct acaacctgta
    29221 aaatatgatt ttgcaccatg tctttaagtg cgccactatg atcgtagtag cccccgcgat
    29281 cttctacacc gaggttttcg ccaaaagtaa tttggatatt gtcgatatag cgattgttcc
    29341 attgagcctc aaaaatatta ttggcaaaac ggatagctga gatgttttgg atcatttctt
    29401 ttcctaaata atgatcaatc ctgaaaatat cttgttctgg gaatacttct ctgatttgct
    29461 ggttcaattc aaaagcagac tggtaatcag aaccgaacgg tttttctatg atcaaacgat
    29521 tgaagccatt ttttgtcata atattttgtg atttcaaatg agaaacgatc gttccaaaaa
    29581 attgaggtgc catagccaaa taatagacac ggttaccgtt taattgatag tgtccatcta
    29641 atcggtcaga caattctttt aatgtctgat aatgcgttga atcatttaca tcatgggatt
    29701 gatagtaaaa atggcttgca aaggtagttg cttcttcatc tgaaggattc aatgcacgga
    29761 ttgtttcttt gacaacttca cggtagtgct catcgctcca gggacggcga gcggttccga
    29821 ttacagcaaa atgctcgcct aaatttcctt ttctgtaaag gcggaacaaa gacgggtaca
    29881 atttacgctg ggctaggtca cctgtaccgc cgaatatcgt aaacaataca tttttttcat
    29941 tagacatgtg gatacactcc tttatatttt atcgacaaaa atcgtgctgg ccgccttaaa
    30001 gctgacgggg attttctttc tatcattttg gatagtgatc ggtccttcat aagctgcgat
    30061 gtcaacgatc tcatattctt cgttgatatt caggtcaata gtgactaagt aatccaacaa
    30121 ttctttttca tcaagcactc gtgcgatacg cacttttgta ccgacaggat aggactccaa
    30181 tgtttgtcgg cgttcttcat ggacaacttc ctctttttta ggaatcgatc ctccatgagg
    30241 acaatgttca ggatgattca aatagttttc taaatgatct gcaagatgtt ccgaagtcac
    30301 atgttccaat acttcagcat catcatggac ttcattccag ctatagtcta aatgttcaac
    30361 taaaaaaact tcccataagc gatgtttgcg aatcagactg ctagcttttt gcagtccgct
    30421 tgcagtcaat tgtacacctt gataagggga atgttctaca agctcttctt tcacaagttt
    30481 agaaatcatt tcactgacag atgcagctga gacatctaga ctagatacga tttgtttatt
    30541 gttgactttc gttgtatctc cacctagttc taaaatgatt ttcaaataat cttctcgatt
    30601 tggtgtcata ttcgatcatc ctttcatggt aaaaaaccat cattagtaag tgtaacaaaa
    30661 aaaacgttaa ttgactattt ttctaaataa aaaacaaagg atttttagac gtttttacaa
    30721 caaaaaacga aagatgatag agaagactca ttctttcgtt tataaaggat atatatatac
    30781 attgggaggg atctattttt cagataacaa cttatatgaa gtgtctgcag attcgtcata
    30841 aagagtttgt tcgggataag aaaagataag ataaaaacca tactgatcac gtacgactaa
    30901 acgatattca tctatttcta ccacagatgt gccaagagac tgaccgttga tcaaaaacgt
    30961 gtaatcagat gtaatctgta attgttgttt ttgctggcta tcactaaaga accatgtacc
    31021 ttgatacttt gagagtcctt ctgacttttc cgcttgtttt ttctttttca agtaaataaa
    31081 acttgagaga acggtaatga gtgaaccaag aaaatagatc atttttttta tcaccaaatc
    31141 actcctttat gagaaaataa tcgcatagac atattctttc ttctttattt cattgtaccg
    31201 aataaaagct aaaatttctc taagactttc gactggtttt tttactgttt ttctacaaat
    31261 tatgatagga tacatagtag gaagaaaggt gacataattt gaagtatcag caagtggaaa
    31321 tagctttttt tattgaccgc ccgaatcggt ttatagcaca ttgtatgaaa aaagacggag
    31381 aaataattat tgcgcatgtc aaaaatacag gtagaggaaa agaggtcctg ataccaggcg
    31441 ctgaagtggc tattgtattt gctcctggac ctaaacggaa aaccgcctat gatctgattg
    31501 ctgtaaaaaa gaagggtgac tggtttaata tcgatagtca attgcctaat cggctggcaa
    31561 ttgatggtat tttagacggc acgatccttt taccaggatt aactggtcca tttacggtat
    31621 acaagcgtga agtaacttat cttcactcca aatttgatat ttatttagag acggtggtcg
    31681 gacaaaaagc atttgttgaa gtcaaaggta tgacacttga aaataaagcg attggtgctt
    31741 ttcctgatgc gcccacactc agaggattga aacatatagg agaattaacg tatgccgcac
    31801 aagatggtta tgccgcttat gtcttgttta ttgctcagtt cgaacatctt catctggcaa
    31861 cgatccatga agaaatgcaa ccagcactag ctgatatggt tcgacatgcg cagcaaagcg
    31921 gagttcaaat cctcgcctat aattgtcaag tatcggcaga tgaggtaact gtcaagcagg
    31981 ccattccatt tgatgtagat atcccttttg aagatcctat acaatagaaa gaaggtaaaa
    32041 taatgatcaa cttaggtatt atcggaacaa attggattac tcatcaattt gtccaagcag
    32101 ctttaagcac aaaaaaatat gaattgacag cggtatattc tagacatttg gaaaaagcac
    32161 aggaatttgg ttctcattat gaaggggata tcgaattcgc aacagatttg aagacttttt
    32221 tcaatattac tcatatggac accatttata ttgcttctcc gaatagtctt cactttagtc
    32281 aagctaagca agcaattttg gcaggaaaaa atgtgatagt tgaaaagcca gctttttcga
    32341 cgccaaaaga aatggatgaa atcatccatt tggcaaatga acacaatgtg tatttttttg
    32401 aagcagcaag aaatatccat gaatcaggtt ttaaaaagat tgccgattac ttaccattaa
    32461 aagacgagat aatcggtgca aatttcagct atatgaaata ttcttcgcgc tatgaccaag
    32521 tattagatgg agaagaaccg aatatcttct cgactcattt ctcaggtggt gcattgatgg
    32581 atttaggtgt ttaccttgta tatgcagctg ttgcttggtt tggaatgcca aaagaagtcc
    32641 attatttccc aagaaagatt tctactggtg tagatggtct tggatggggg atcttacgtt
    32701 atgagaattt tgatgtatcg atccagccag gtaaaatcgg tgattcttat ttaccgtcag
    32761 agatttattt tgactcagga acgctagtga tgaatggagt caatgcaatt gaacaagcac
    32821 aatttcatga tcgcgcgcat aaagaaatca ttgatttggc ggtaacagct gcagaaaatc
    32881 caatggcaga tgaagcagag gattttgcca atgtcatggc tcatccgaaa gatccagctt
    32941 ggggattgtt gtatgaagag tggatcgagc tagctagaaa tgtgaaccaa gtgatttatg
    33001 atttaagaaa aaatggcggc atcaaattcg atgcagataa tgaggaagat ttttaatgaa
    33061 cgaatttgta caagtatttc ccgaaaattg gcagaaaaaa tatgaggata aagggtttat
    33121 ctcaccttct cttattcaac gagcagtttt tcagccacta agtaataaac aaagtatagt
    33181 agcggtttct cctacaggtt caggtaaaac actggcttat ctttggcctc tactactaaa
    33241 cgtggaacca ggtgaagcaa gtgcgttggt catttttgct tcttctcaag aactagctat
    33301 tcaagtagca gatgttgcac gtgaatgggg aaaagacaaa gagttgaaag tccaatcttt
    33361 ggtgggcgga gccaacgtca aacgtcagat tgagggtttg aaggaaaaac cagaaatctt
    33421 gattggtaca ccaggaagaa tattggaatt gatgaaagca aaaaaaataa aagcacatca
    33481 agtgaaaaca atggtatttg atgaagcaga ccagctattt gacgctggga acagccaaat
    33541 cattgatcaa attcttcatc aagctccaac agagtatcag ctagcttttt tttcagcgac
    33601 agcagatcgt tcccttgaaa gcattgaaaa aatcactggg aaaacgtttg agacaattga
    33661 cgtgacagca gaggacgatt ctcgaaaagg actgagacat tactttttac gtgtaccgat
    33721 acgaaagaaa gatgactact tgagacgtct cacgcatata gaagattttc atggtctgat
    33781 tttctttaat caactgactg aattaggcgt aatggaagaa aaattgctgt atagaggtgt
    33841 accggtagga agtctggcct ctgatcagaa caagctactc cgaaaagcag cgctagaaca
    33901 attcaaaaag aaaatggtca gagcactttt gaccacagat gtggcggcta gaggtttaga
    33961 tattacaggt cttccttatg tagtgaatgc agaagttccg ttaagtgaag aagcttattt
    34021 gcatcgttcg ggaagaactg gtcgaatggg taatgaagga atagtaatta cactcgtaca
    34081 agataataat ctaagagatt taaaacggct tttacgtcca tcaaatataa cacttgaaga
    34141 gattttttta tacggaggta agctgcaaac tgagcagcca accaaagaag atgcagctcc
    34201 tgcagtaaat aaaaagtatg cgaaaacttt ttctggaaag gagcagaacc cagaatataa
    34261 caaagaaaaa ataagaaaaa aagttaaaaa taaatcaaaa aaagagagaa ataaaggagc
    34321 aaggcgcaaa taagcgcctt tttatgctat gattatgaaa acgggaacaa aattggttgc
    34381 cagaggaggg gttatgtgaa agaacgtcaa gaagagatct tgcagctatt gacagaaaac
    34441 caacaaggat tgacagcaag tgatgtagct gagcgcttaa ctatcgatcg aagcaatgca
    34501 agccgatatt taagtgaact atacaaggcc catcatattg taaaaaccgc tggccgacca
    34561 gtcgtttact ctttgccaac ggaaaagtca aaatctgatg aagtgcatgt cgactcttct
    34621 acgcaagtga cttttgaaac actcgttgga gaaaatgatt ctttaaaagt cagcatacag
    34681 caggcaaaag ctgcgattct ttatccaccg cgggggttgc atacgattat ttttggagaa
    34741 actggtacag ggaagtcgat gtttgctgaa tgtatgtatc attttgcaat cgattcagag
    34801 atgctttctg cagatgcgcc atttgtttct ttcaattgtg cggattatgc tcaaaatccg
    34861 caactgctct ttggacacat ctttgggatc aaaaaagggg cttacacagg agcagctcaa
    34921 gatagtcccg gtctaatagc caaagcagac ggcggtatat tgtttttaga tgagatccac
    34981 cgtttaccgc cggaagggca ggaaatgctg tttactttca ttgataaagg tatttaccgt
    35041 ccgcttggag aaagtgcaca agtacatgaa gcatctgttc agatcattgg ggcgacgact
    35101 gaatcttcag aaagtttctt atctacgttc aatcgacgga ttcctatggc aatcaccttg
    35161 ccgaatcttg cttcacgttc actggatgag cgttatgaaa tcatctctct ttttatcaaa
    35221 caagaagcga atcgtttgaa tcaacgtatc gatatcgaaa aagaagcgat tcttgccttc
    35281 atgctttatg atgcggaagg aaatatcggt caagtgaaac gagacttgaa actagtctgt
    35341 gcaaaatctt ttttacatta ccgtactcat catgagaaaa agctaatcat tcgaaaagaa
    35401 gaactttccc ttcaagtaca aaaaggatta ctgaaaatca aggaaatacc ggaacgtctc
    35461 gaccgattca tggacagcaa aagtcagtat ttgacatttg aaccaggatt tgctgatgtt
    35521 gtctggtcac aagatccaga acgaaacatg caggtctata acgatattga ggaaaaagtc
    35581 acttctcttt ccgaaaccgg tgtggagaac attgatctag agaccctcat ttcaaaagat
    35641 gtggatgctt atttccagac atatgtcaaa gaattgacta aaagttcgat tcccaaagat
    35701 cttttgccag atgaaatctg gcggttaacc aatcaattgt atgatgtggc tgaaaaacgg
    35761 ttagaccgta tttataatga aaaagctcgt tttgcttttg ctttgcatct gcaaagtaca
    35821 ttggatcgtg tgagagaagg tcatatgatc gtccacccag atttgaataa cgtacggaaa
    35881 aattttaaga gggaattcca ggtagcaatc gatctttcaa cgatcattga agaagaagaa
    35941 caagttgaga ttccttttga tgaaatcggc tttattagta tgtttctttc tatcaatcta
    36001 ggagaaagtg agcctgttaa agaaaacaaa gtagatgttc tcatattgat gcacggcaga
    36061 cagactgctt caagcatgtt ggagatggca caagaactat taggaacaaa agtagggaaa
    36121 gcttttaata tgccactggt tatggaagtt caaacaatgt atgaagaagt gttacaatat
    36181 gtcaaaaact atcaagagca tttgacgaat ggcctactct tgttaacaga tatgggatca
    36241 ttaaacacct tcagtgattt gatttatgaa gagactggca ttcggacgaa agctatcacg
    36301 atgacaagta ccatgattgt gatagaagcg atacggatgg caagtgttgg aagaagctta
    36361 gaagatattt atcaaaatat ccagctttcc tttgaatcga tcgtacgtga tcagttcaaa
    36421 gcggaaaagt ctgaaacttt acagcgtaaa aaagccgtaa tcgtgacatg ctttactggt
    36481 gaaggagtag ctgccaaatt atatcagcgt attatgccag tgattaatca aaataaggta
    36541 gaactgatcc agatgcagtt tttagaacgt gaatcattca aaaaacacat cgatgcctta
    36601 ttggaagaat atgagatcaa agcaattgcg ggaacagttg atgttgatta tcaaaatatc
    36661 ccattttttt cagcctatga cgtttttgat gatgaaaaac taaatatttt aaagcgtata
    36721 gctgatgatg agatcccgac agctaaaatt gtcgattcac ttgctggatc attaagcgat
    36781 gtcttttcta ttgatgaact gatccgttca ttgcaaaaga cagttcagca gatccagacc
    36841 gatttgtcga ttatcgtgga acctggagta gatactggaa tcgttatcca tttagccttc
    36901 atgttagacg gattgatcaa acaagaaagc catcggcaat ttgagaaact gtctattttc
    36961 tcaaaaattt atcgtttgga aatggatatc gttcgggcaa acttgatggc actagaacga
    37021 aaatatcagg taaaaattcc agaagatgat atcgcatttc ttacacaaat gtttcttgaa
    37081 aataaaataa aaaaatgaac acactaatca tactgtttac acactaaaca tctgtgtgcg
    37141 cactataaaa aagagctaaa aagcatgaaa acgctatttc agctcttttt tttattggca
    37201 tgcttcttgc gttatataaa agtgtaaaaa aataaaagga gtgttaaaaa tggcaaaaaa
    37261 aacaatcatg ttagtttgtt cagcagggat gagtacgagt ttattggtca caaaaatgca
    37321 aaaagcagca gaagaaaaag ggatggaagc cgatattttt gcggtctctg cctcagatgc
    37381 agataataat ttagaatcta agaatgtcga tgtattatta ttaggtcctc aagtacgttt
    37441 catgaaagct caatttgaac aaaaacttgc gcctaaaggt attccattag atgtcatcaa
    37501 tatgcaagac tatggcatga tgaacggaga aaaagttctt gcacaagcag aaaatctaat
    37561 gaaataaatc aagtatgcag ttgggggtat aacaacgtgg aagatcaaca aaatctagaa
    37621 gccatcatgg ggttaatcat gtttggcggt aatgcaaaga gcgatgcaat ggaagcgatt
    37681 gcggctgcta aaatcggtga ttttgagtta gcggatagga aaatcgctga tgcagaagaa
    37741 tcacttatac aagcgcatca tgcacaaaca gacatgttga cacaagaagc acaaggaaat
    37801 catatgcaag tgacattatt gactgttcac agtcaagatc acttaatgac atctattgcg
    37861 tttactgatt tagcaaaaga aatcatcgaa ctttatcgtc gcgtatacag cgaataaata
    37921 caacttcttt tttgaacgga agaagaaaaa tttttgaacg gattttttat tttgttataa
    37981 ggagaactct ctttatataa aaaacttata ggaggaagta aaaaatgaac ggactatcaa
    38041 gttggatgga gaaatacatc ctgccggttg ccgcaaaaat cggagcgcaa aaacatttag
    38101 ttgctttgcg tgatgctttt atcggcacac tgcccgcaac aatggcggga tcagtcgctg
    38161 taatgatcaa tgcaattatt cgtgatttac cgcaacagtt taacagtacc tatgctgaca
    38221 gtttagcagc agacaaagga atctttgccg tattgaatgt catcatcgga atcaatggtt
    38281 ttgtctggaa cggtacacta gcaatcgccg gattgatctt tgccttttct tgggggtata
    38341 atcttgcccg agcttatgga gtaaatgatc tagctggggg gatcgttggt ttagctacct
    38401 tgattcaagg tatttccttt ggtccagcat tatcagcagc attagatgtg aatgttcctt
    38461 caaatgtcgc agatgcaatc aatagttctg agattggtgc aacgattgca gatggcacac
    38521 tgtcagttgg attatggggt tggctaaaac tagatcattt gaatggaaac gcttatttta
    38581 cagttatgat catgggagct atttcagtca ttattttttg taaattgatg cttgccaaca
    38641 ttacgatcaa aatgcctgat tcagtaccac cagcagtatc taaagcattt gcagccattt
    38701 taccagcgac gatcgcttta tacgtcattg ctattatcaa ttatatcgta ggtcgtgtag
    38761 ctgatgggca actgatcatt gatttggtgc aaaaatatat tgcagaacca ttcctaggat
    38821 tatctcaagg gttgggagca gtattgatcg tcacagtatt tgttcaagta ttctggttct
    38881 ttggtattca tggaccaaat gtattggcac cagtgctaga gggaatctgg ggacaagcac
    38941 aactaatcaa tattgatatt ttccaaaaag gttataacgg aaaaactggt acaccagccg
    39001 tgttagatgc aatcgaagat ggaaaagctt atatgtgggt ccgcggatcg ttcgatgctt
    39061 ttgcatggtt tggcggatca ggcggaacga tcgtcttact gatagctatc ttgattttct
    39121 ctaaacgtgc agattatcta acagtagcta aattatccat tgggcctggt atcttcaata
    39181 tcaacgaacc agtgatgttt ggtctgccaa tcgtattgaa tgcaatcatg tttatcccat
    39241 tcttgattgc tccagtagta gcaacagcaa ttggatggac agctacttat cttggcctag
    39301 tcgctccggt atcgcagcaa gtcacatggg tagtaccgcc gttcttattg tcattcttag
    39361 caacaggagc ggattggcgg gcaccgatcg taacattagt atgtatggtc gtgactttct
    39421 tgatttgggc accatttgtc atctctgcaa acaaaatgga ccctgccgca ggcgaacaac
    39481 aataagatga acgtgaggag cgggacgctt taagtttcgt tcctcataat gaattttcga
    39541 ggaggaactg aaatgattac aattgccagt gcaatgcaac aagatgaaat caaagaattg
    39601 ttagaaggat acaatgaaga aggaatgact tttacattta aagaaaaaca aggaatcaag
    39661 ctgttctttg aaacaagtgc agaagatccg gaagttgcgg ctaaaaaagc aaaggaacta
    39721 atcaaagcac agccttgggg aacagtcctt tattttcaat caacagctgt ttagaaaatg
    39781 gtttaaaaag ataggatggt tgagatgata aaaaacggtt tatttttatg tagtattggt
    39841 tctttgatcg tgttgtatag tttgaatcca cattcgcaaa ggtatgattt gtatagtatg
    39901 gtcacaggtc tttttctaac aggattagga atctatttct tcatgaaggg gaaaaaaaga
    39961 gaagaagcaa aggagaaaaa taactaatgg aaatcacgaa aaaattaaat attccagcat
    40021 cgttttttta cgataaagtt atggactctg tccttttcga tgtacgtaaa gcgaccggca
    40081 aatcagtaac tagaaaacag ctgaaaaatt tggagtacgt caaacaattc tcgcaaaata
    40141 accgggctcg cataaaaatc gaagaagtca ttgaaaacca gtcttataag tttcgtacat
    40201 cgacaacgaa gaatgaattc gtcgttcatt atcaaatcaa accattggac gattcgacct
    40261 gtgaggttca ttacacagaa aaaatggagt cttatggcat gcttcaaaag ttgaatgata
    40321 tgcttttagg aacaatcttg atgtatttta aacggagacg tttcaaaaaa atgctagata
    40381 tgatcgaagc aacgtattaa atcaatgaaa catggtacta tttagttatt gaaaaatgaa
    40441 gtaagctaga aggaattttt cataggaaga tagatctttc ctgcgaatcc tcactagctt
    40501 ttttgtagga aggggcagca aaatgacaaa caaagtaaga gagctaggtg tatcttcgat
    40561 tgaggaaatg tttgatttag ccacttatgc atttaatggg gcagatacac ctgaaaggcg
    40621 agaacgtttt cgtacacttg cggagaattc ttggaattac ggattttttg atgaggagga
    40681 tcggctaaca agtcaagtca tggcgacccc ttttccagtg aatttttacg gacaagagta
    40741 cctaatggcc ggcattggct atgttgcttc ttatccagaa gcaaggggac aaggcgggat
    40801 caatcagatc atggaaaaga tccttgaaga ttgccgtgat cgtaaagtaa gcttatctta
    40861 tctggcgcca ttctcctatc ccttctatcg gcgctatggc tatgaacaat catttgataa
    40921 aatcagttat caactaaaca gtcgtgatgt gccgtttatc aaaaaaaaat ctggaaaaat
    40981 aaagcgtatg gattttgaag atgcaaaagc tgcaatcaga agaatttatg aacagatgcc
    41041 ggaaaaccaa cgagctggtc tgaagcgcga agactggtgg tatacgtata aattcaagca
    41101 aaaaggcaat taccagtttg ctttgcattt tgatgataat gaggaagcaa cgggatatat
    41161 cgtttatcag cttgcaacgt cttcctttat tattgcggag tggggatttt tggatcatga
    41221 tgctttttgc agccttgttc gcttcgtaag ttctcacaat ggtgcttttg aaacatttga
    41281 atattcatgc ggctacggcg gtaatgatca aaattatcta ttagaaaatc catttgcttc
    41341 tgtaatgatc acaccttata tgatggcgag gatcgtagat atttctttgt ttttggaaaa
    41401 ttatccattt aaaaagagac aagctgcatt tgccctacaa atagaagaag atcattatgc
    41461 gaaatggaat gaaggaatcg tggaagtaac aatcgaaaat ggaaaaaatc atctctcaaa
    41521 agtagaacaa acaaaactcc caatcgttcg aggaagtatc caacatatca cgcagctatt
    41581 attagggtat cgtaaagtgg aagagttggt attccaagaa agaatacagg tgacaaaaga
    41641 atatgaagaa acgttaagct caatcttgcc acagcaacag ccaattctta atgactattt
    41701 ttgataaaaa acgggtgatg acaatatttt tgtcaccacc cttttgtttt tcatttggca
    41761 tttgaaggaa aatgttaaag taaatcctct tttttcgtaa atttgaattt tttgttttct
    41821 tttgttttag ggttttcttt tttgtggtct tggattgctt ctttcgtaat cttttcccga
    41881 ttttttttag atgaatctaa gcgttctgcg tatacttttt cttttggctt atcattcatt
    41941 ggaaaggacc tccctacatt atttcattct acctctagtt tatcatctgt taaggactag
    42001 tggaaacgtt ttgcctaact tataagctga tttttttagc agataagctt gcaagtaaaa
    42061 aacaaacaag ctacaattga tttattgaaa ttgttcctgt agctcagtag gatagagcaa
    42121 tcgcctccta agcgataggt cgctggttca attccagtca ggaacgtaca aataacccct
    42181 gtatcctttg tgatacaggg gtttgttttg tgtttgtgcc aaaaatgtgc caaactagtt
    42241 atcattttta tataaactat cgaacacagc attgattttt tctttatcct gatcttcaag
    42301 ctctcgaaca atatgaagat aagtagacat tgtagtttct aaactgctat gtcctaaacg
    42361 tttcgatacg ctaagtatat ttactccttg ataaagtaaa atagatgcat gtgtatgcct
    42421 tagtccatgc aaagtaaatt gcttttcaat ccctaattct tttaattttt tgcgcaaata
    42481 tttgctgacg gcgtttgatg aaactaatcc attttttaag ttgaaaaaaa caaaattatg
    42541 agggttttta acttcaaaat tctcgaataa ttctttttga ttgattttaa acttttttaa
    42601 gagatcaatc gtatgtttat caatggaaat tttcctattt gaagtttcgt tttttgtttt
    42661 tccccattca tttaatttat aattccatgt tttattaata gtgatgattt gatcttcgaa
    42721 atcgatatct tcccatgtta atcctagaag ttcagcaaat cgcattccag tagcaccagc
    42781 aactaacacg agcataggag aagagtactg cgcagaaagg ttttcttcta cgagtttcat
    42841 taaagattta aattgatcat aatctaaata tttatcttct tttggcttca atgaatcttt
    42901 tcctttgatt actgcttttc tagttggatc aaacggaatt aatccttctt ctacggcatc
    42961 tttcaacgat gctctaatat ggttattaaa cttaataacg gtggatttta catggtcttt
    43021 cgcatactta tttaaaaagc gttgatatcc aactctatct aaatcagaaa tcaataccgc
    43081 tggcatatat ttctttatgt tcattaacgt atcttcgtat tttctataag tgataggaga
    43141 tactgttcct tctttataaa gttgcatcca atcctcaaag taatctgata ataatagatt
    43201 tttgcgatcc cctttaaggc ctttgttcaa gttatattct aattcgttgg cggcatcttt
    43261 tgcttcgcct tttgtcttaa atcctgattt tcttatcttc gtgtattttc cgtcatcttt
    43321 tttgtatgaa atttcgtatt gccaactatt tccacgtttg actaatcttg ccataattga
    43381 atcagctctc tttctctgat acaataggaa ctataaagaa gcctactgta taggtttgtt
    43441 ttttcataga acacgcttgc tttggacggt gggcgtgttt ttatatcaat tagttatgaa
    43501 gagcaattga aactgtctct gttccaaagt aacctgtttg tgcttgcaat acattatttt
    43561 gtgcatttgc ttgggcttca gagatatcaa aaactatttt accagtttgt tgcatatcag
    43621 gatttaagct ttccataaag aaagagttag tgatattacc attttcatct tgatttgccg
    43681 acatagatgc agccgaatca gcttcgaaag tttttccatc tgcttttaat ttgaagaatg
    43741 agctatcaac agtcacagcc ttatcacctg cattttttac agataagtca actactaaga
    43801 aagtgtcttt tgcgttagta ggaagtacag atgggccaac ttgttttact acttcaacgg
    43861 agtttacttt gtattccatt ttccctacag caacgtcatc accgatttta taagtctttt
    43921 cttcttttgc tgtagtttct tttgtagttt ctttattagt acttgttgat gttgcagtag
    43981 ctgaatcttt gttttctccg ccacttagag caccaccaat accaaaaaac aaaagtaata
    44041 ttaataccca aaaccacact tttttgtaaa aaggtttact aactttatac attttcccat
    44101 cttgacccat aacttttttt gccatttaaa tattcctcat ttcttgttat aatatatttg
    44161 tgatctcaga aatgaggtat gagtccgtgt tgcagcacgg gcttttttta ctgtgcataa
    44221 gagtattttt tcttgaaata agactggcaa acattaaaac attctgttct taacttatta
    44281 ttgatagaat agaactccat gaaattttct aatttgaact gagattcatc agtcagttcg
    44341 ttctcaataa agatatttag taaaatcata attgcgattc tatcagcttc agtttcgaat
    44401 tttgaatgaa aagttgtaga gttatcgtac agtactgaat attcaaaatg tgaagcaatg
    44461 aaatgaccga gctcgtgggc taaatgaaaa gcttcagaac tgtcttcgtg tagtttttca
    44521 ttcagaaata ctattcttgg ttttggataa taaaaacctg gttcttccat ttccatatag
    44581 attaacttta aattatactc actcagcatt tctttcaact ttaaatacat acaacccatc
    44641 actccaacta ttcattttcc tctaaagctt tagcaattgc aatcgcttta cgcattgtct
    44701 ccttagatat ttcttttcca tcaaaagaaa aaacagtatc gtcttctgat aaatccacat
    44761 gtttaggggt ttctttttta tctcttccta gaagatagtc tatagaaaca ccaaaataat
    44821 ctgatacttt tgccaaacct tcggagttag gtgatactga tttccattta ctgaaatatc
    44881 catttgaata tcccaatctt ttttctaatt cccttacgga tattccgttt tgctttgtta
    44941 attcttttat tttttcgtat ggattcattg atatgtcaac ctttctagac tgacaagaaa
    45001 aaatatagaa taaaactcta tttatctgtt gacaaattag agttaaacct ctatacttgt
    45061 tcttgtaaac aaatttaaca actaaaaaga caacaaaaaa cacttttgat tattaaacgc
    45121 caaccgccaa aaaagctttt aaaatcaatg tttatatgtc ttatttaact atgtacaaag
    45181 tatagaataa aactctatgc tttgtcaatt gaatttagaa aaaagttgtt aaatttgttt
    45241 acgaatataa aagaaaggaa tgagaaatat gaacacaccg caaattttta atttcgaaca
    45301 aaacgaagtt cggacaattt tagtaaatga tgaaccatat tttgtaggca aagacgttgc
    45361 gagtgttttg ggttattcaa acactaaaga tgctttgtcg cggcatgtag atttggaaga
    45421 taagatgggg tcgcgaatca cgacctcagg tcaatcaaga gagatgacaa tcatcaacga
    45481 atctggtttg tacagtttaa tcttaaaatc aaaacttccc tctgccaaaa aatttaaacg
    45541 ttgggtaaca agtgaagtgt tgccagcaat tagaaaacat ggaggttatc taactccaga
    45601 aaaagtagaa gaagctttgc ttaatccaga tacaatcatt caattagcaa ctcaactaaa
    45661 agaagaaaga actggaagat taatcgcaga acaaaagatt gcagagtacg aacctaaaat
    45721 ctcctattta gatagcatat tatcttctac agattcagta acaattagtc agattgcagc
    45781 agattatggg atgtctccac aacagatgaa taaattactt cataaactag gtattcagaa
    45841 aaaagtcggt aaccaatggt tattgtgcaa aaaacacatg aaccaaggat acacaaaatc
    45901 tcatacaact gagatcccga aagccgatgg tggcactaaa attgtaatga ataccaaatg
    45961 gacacagaaa gggcgtctat ttatctacga attactaaaa aaagaaggat attaccctca
    46021 aatggattta gaggaaattg gttagaaagg agttttagta tgactgacat tgcagaaatc
    46081 actcaacgag atagagaaaa aatcaaagaa tatgtcgaaa gttcaaagtt cttaacttac
    46141 accatgctcg ctgaaagatt cggcattagc aaaagctact tatctttaat tttaaacggt
    46201 aaaaagactt ctgcagaagc aaatagaatc atagattcga ttattactat gtacgaattg
    46261 taaagggagg aacagctaat gcaatatcta gaagcgaaaa tcccagttcc agaaggctat
    46321 gtaattatct cccaagtgga ttatgaggag ttaaaaaaag ctgatgatac tggtagatgg
    46381 atgacgttgc cagaagtgct agaacggatt aacagaaaat atgattggtt tacttctaga
    46441 gttttaaaga acccaagata tagaaatatt atcgatatcg aaaaaaacaa aaatggattt
    46501 gtctattatc cagttgaagg aagagacaca tatctatttt taagaagtaa aacacttgaa
    46561 tttttagaaa caaatttttc ggaaatctta aggaggcaag cggatgggaa aatttaatag
    46621 agcgctagta ttcagcgcac cgctaatcat ctacgcttta ggactttggg gaagcagaca
    46681 agcgttgata ggaacgattg tttacatggt ttggattttt atggggctgg atgaagctga
    46741 gtacaaaaca aaaaagccag tcgggaggga ctgactaatg aaaaaaagtt taatgactat
    46801 aaacgaaaaa caattgaaag aaaaatttaa tgatctcatc aaagaatttg taaaagaaac
    46861 tggagaattt cctaatcaaa ttcatctagt tgcggagggg catagccggt atcaagctgt
    46921 gaaatttgag atgaagaaac aaatctattg aatttagcag tacctctact tgtaagaaca
    46981 tttattgtaa tgtttttttc gactaaagat tcatcgtatc taaaaaccaa cgtagtaatt
    47041 tttgactcat acggtggaat ggtaataggt aatgacaacg gaggaaattt tgatagatca
    47101 gcaccttttt ttaaagattt accagaatac gcacgtatac catgtggaag ttcgtcatac
    47161 attgatttta ccgttacaga ataattatca ccaatcattg taaaagcatt taaaggatca
    47221 ggaattccag aaatcgaaaa ctcaataatt gtaacaggta aagaactgtt atttgttaac
    47281 aatacagaat ctataatcct gaatttattt tgatggtaaa catctggttt ggaatcactt
    47341 tctctatcta tcaaccattc ttcgcattca gcgaagaaat ccaattttaa attaaatttt
    47401 ttattttttc tatctgtata ggagatataa aaagcaaatg ttgaaaatac tagagacgta
    47461 ataggcaaaa taaaatcttt aatggtttta acaatgttat tccagtcaaa ttgtttaata
    47521 aagtcaataa gactcaattt ataccaccac cattttttat ctacattata tcaaagagga
    47581 gagaagaaat aatgcaagaa ttagtaattt tgaaaaataa agaagctgtg actacgagca
    47641 tacaagtggc agaaagcttt gagaaaaaac atcaacatgt tttaagagat attgatgcac
    47701 taaaaaaaga tgtgtccaat tttggacaga tgttttctga aggtaatgag ccagattcct
    47761 acggaagaaa tcgacgagtt ttcttcatta gcagagatgg atttttcttg ttagctatgg
    47821 gatttacagg aaagaaagct atttacttca aacaaaaata cattgaagca ttcaacgaaa
    47881 tggaagatgt tattcgcaag aatactgttc ctcaaacaat tgaagacatg atgatctacc
    47941 aactagaaga aatgaaagat gttaaaaaag atgtctccat gcttaaagat actatgcgaa
    48001 ttagcggaca acaagagttt gaaattaagc aaaaaggaaa tacgaaagtt atggaagttc
    48061 tagggggaaa agaaagccga gcttatgaag aaatcagcaa aaaagtattc tcaaaatttt
    48121 ggtctgaatt taaacgtacc ttttcaatcc caagatatgg cgagttacct cgtaagagat
    48181 tcgatgatgc tgtttcattt attgaaatgt ggttaccaga aactgcgatt cgcatggaaa
    48241 tcgatcaact gaacagacaa caaagacttt ttggtgatga aaatgaatag agctgaagcg
    48301 ctaagaatcg ggacggtaat tgctaatcgc tggtggagac acaataaacc aatcatccta
    48361 agccaacaac atattgacaa gcaaaaagca tggcaacaaa taaaaaagtg actccgccgg
    48421 caagcaaaga gtcacaaaga aaacacatca taaggagatt ttagcatatg gaaaaagaac
    48481 tttccactct agatcaatat ttgactgatc ctagttgggg caaatcgaat atcaaggaaa
    48541 caaataatcg aaaaatcaga cgaaatcttt tgacggatga agaactagca tgtgatcaag
    48601 acgatttggg aaattttgtg agtatttggg atcatgtcta tcttatccat ttatcgagga
    48661 agtccaaaaa acctgaatat atctatgtca tcgaagatgg cttgattgat gcgctagaag
    48721 agtatgacag agataacttg attgatatct cttattacgg atcaggtaag aaatacattg
    48781 ctgaaatgga ggcagaattt gatgagtgaa aacaaaggga caacgacttt tgaaaaactt
    48841 tttagtcgca agttaaataa aatactcaag aaaaaaggaa attttgatta tttatcttgg
    48901 gctcacgcat gggagattat gaaaaagaat gatccacagg caacggtaac tattaatgag
    48961 tataaacact acagagttgt ttctggaact catcaagact ttcttgttga ggaatataaa
    49021 ccttttctta tggatgaaac tgggacttat gtatctgtct cagtaacggt taaaggacac
    49081 acggaaaccg aattatttcc tgttttagat tatcgaaacc aaccagttgt taaaccaaat
    49141 gcaatgcaaa tcaataactc attgaagcga tgctttgtga aagcattggc tctacacgga
    49201 ctgggattat atgtatttca aggggaagat attccaacac cacctagaat cgatacgaag
    49261 aaattaaaca tgctagagac gattctagaa gctttcaatg agcagatggg taaagatatg
    49321 accaaaacct taatcgaata tgttaatgag cagacagata aattagggct cttagctgat
    49381 aacgttgaaa ctattgaaca gttaagctat gagcaatgtg ccttgatgga gcgagcaata
    49441 gcagctaaga gaaaagaatt agataagaag tgatatgagt gtttaaacca ttaatcgatt
    49501 catattcagc ggttctgaaa aagttcaaag gaaaagacat aggtgcaacc atcaatgagg
    49561 aagtgaacat tgatcgacta aagacgatgt atgacggcta cgatggtgat cgagttattg
    49621 aaattcgttt tattgatcct agacgtttca cagtacagca acgaaacttc atctatgcac
    49681 tcataggcga tattttcatc gatacaggca tgccaacgga cttctggaag gaattctttt
    49741 acttccgctt tgaaggtgtc acagggcgca aaataagcct caaagatgaa tcgaatacga
    49801 ctgtgagtga tgctaacgtc ttagcaaata tcatcttaga tttcatcttt gaacatcata
    49861 ttcctttcaa agaaggctat gagattttac cagcgaatca agaatattac ttctacaaat
    49921 gcatcacaaa aagagtctgt tgcatctgtg gcaaaacagg agctgatatc gatcactttg
    49981 acaaagcgct aggaagacga aagcgcaaag aagttgatca ttcagagtac acatttgcag
    50041 cactctgcag aatccatcac acggagaaac acaagatagg tgtgatcaat ttcaaaaata
    50101 aatatcaaat caaagggatc aagttaaacc aggaaacaat taagaaactt agaataggag
    50161 gataaaaaat attggctgac aacaaacgat actactattt aaaactaaaa gagaactttt
    50221 tcgatagcga cgagatggtt cttttagaaa gtatgccaga tggatacatt tattctaata
    50281 ttcttctcaa actttattta agaagtctga aacatgaagg caaactaatg tttaatgaca
    50341 ggattccatt caattctaca atgcttgcga ctattacaag acactctgtg ggagttgtag
    50401 aaaaagcagt acaaatattt cgtgatttac aacttattga ggtattagat aacggagcaa
    50461 tttatatgtc tgatatacaa agttttattg ggaaatcttc aactgaagct gataggaaga
    50521 gaaaatacag aaaagaaatt gaggaagcaa aacagaattt aataacaagt ggacaaatgt
    50581 cggacaaatg tccggacaaa actacaccag agttagagat agagttagag aaagatatag
    50641 agttagagaa agatatagag aatgtaacgc cttcgaaaaa atcgaaggct aagcccgtcc
    50701 gtcataaata cggagagtat aaaaatgttc ttttgtcaga tgagcagatg gagaaactca
    50761 aaatagaatt ccctaatgac taccaagagc gaatagaacg gctatctgag tattgtgaat
    50821 catctggtaa gacttataaa aactatttgg caactattcg aagctgggca agaaaagaaa
    50881 aaagtgaatc taagaacgca agcagtggat acaagcgcac aggaagacga gagaagcttc
    50941 ctgagtgggc aatcgaccaa gaagcctatc tcaagaaaaa agcgctagaa cgagctaata
    51001 gacaatcaaa agcaccattc taagaggtgg gaaattgaaa atcgattatc tagaactaat
    51061 taatgaaata gcaaagtata aaactggtga ggaaatagaa atcctgagag acgtatatga
    51121 tcaactcgaa gaagctggaa tcgaaggaat taagaatgat cgttcgagtt ggagtaagct
    51181 cagatactat ttcgcacttt atatcgatac aacacaatta agaaatttag catataccaa
    51241 attactattt gttgattgtg ttaaaggctt gcaaaaacat cttaatgaac ttgagcaggt
    51301 gtaatcagat ggacctaaag acatttacag cacagattga actaatgcat caagaagctt
    51361 taagacaaag tgtatcgtac gaagacaagt ggctcaacac gttccacggt ggacgtgaga
    51421 gcgcacttga tcaagtactc aaattattga aaggggaacg tcgggatgga taagaaagcg
    51481 gcttggcgaa aattaatgtt gctgattcaa gatgagaact ggcaagaaga tgaagcagtg
    51541 gttgctgaag ttcagcgtct agaaaagatt gctaacggac gtatacgaaa aaagcctgat
    51601 aagcggaaac ttcgcaaagg aaaaatcatc gttgttttgt atgaaggtaa cattttgatg
    51661 caaggaacgg caagagagtt gtctgcagaa actgaatata cgagcggaac tattcggacg
    51721 tacgcgtggc ggaatcacgt tgataaaaaa ggacacgaat ataagtattt ggagggcagc
    51781 aaatgatacc gaagtttaga gcgtggtaca caccatttaa aggtaaaaca attggacaag
    51841 aaatgaaata tgggcaagca ggaaggttga tcactcatgc tgaaatggct ccagataaat
    51901 atgtgcttat gcaatccaca ggactgaaag acaagaacgg tgtggggata tttgaagggg
    51961 atgtagttct tgtcaatgta agtaatggtt ttgatcattt agttaatgaa aaaacggttg
    52021 tacaagaatc cgagtttcat tctggattag tttgtaaatc attaattagt ggaatggaat
    52081 atagagtatt caaacacaaa aagatggatt atgaatatga agtcatcgga aatatttacg
    52141 agaattcaga gttattggag gaacagcgat gaataaacag gaaacaatca aaaagttaga
    52201 aagtattaaa gcgataggaa atgatgcaat agctgcttgc tataacgaga gtatgaatgc
    52261 aggtattacg ttaatgaaaa aaatagacga accgcagaaa cacgttatgc cgaagttttt
    52321 tgacaaatgg gcaaaacaag tcctggaaaa acgtgacaag ttttatgcca tttctcttat
    52381 tgcacgtgca ggttggggat atggtgttga ttttgaactt agcgagaacg gattatcatc
    52441 agaaaacaaa gagctgttgt actggcttgt tgataaatgc agcgacaatt atcctaataa
    52501 aaagaaagca atagaagctt tgttatacgg ctacgaggtc gagaaagaac cgttgtatca
    52561 cgtgaagcta aaaataccag gcgtaacata ctaccttatc caaacttttt taatgccagg
    52621 agatactcat atgtgtttct cagcggctac agaacgttat ggggctaaat ggaaaaatac
    52681 ttttacggaa tcagaaataa aagcaattga tgaaagatac tggccatttg ctgtgccagt
    52741 ggaagaggag gcagaaggat gaaaaaattg caccaactca tatctgagaa agaaagcgaa
    52801 ctccaaaatt tagaagatag tttgggattg gggtttccaa ttgttgagca agctaaaatg
    52861 actcaaatca gtcatctacg acttgaattg gaagatttaa gacaaataga aaaatcaatt
    52921 caactcaacg acaaccagca aatcgtgttt gagtggttga aactaactgc gccaacagga
    52981 aagccaatgc aagttgtatt ttggatgatg aataatgcag catgggggca tttagacgaa
    53041 ttaagggatc ctttgatgga attaacagac aaagagcaat tcgaagtcct agcagcattc
    53101 gctcaatggg gattagaaca ggaggaagcg gaatgaacaa cagacatcgc agaataacga
    53161 aactaagaaa acaggaactg aatgtactaa aggcaaagtt cgaaaaagaa tacggagttt
    53221 ctgcagaaga agcatataaa gtggcaagtc agtgtgttgc tgatgcgagt aatgctattc
    53281 gtaagtttgg aatttcgata ttaagtgatg atcgtaaatg ggaggatata gaatgaaggt
    53341 ttatgtagta aggttcggga ataaatttta tagaagtgat gaacgctcta taggcaataa
    53401 tgtgttattc cttgtagatt ttcttcaaaa cgcaagatgg tttgataatc tcgaagaagc
    53461 taaccaagtt tcacgacgac ttggtggatt aacgcaagta tatgaactgg tcactatcga
    53521 tcatgagggg gtagaaagat gaaactaaaa gacggatttt acgctagtag tcatggtatc
    53581 ggcggtttaa tgctaggtat gccgacaaag aaccctaaaa cacgtaagaa accaaaattc
    53641 aaagtcggtg acatggttcg ctgcgaagca gaggagttca tctatccgtt tcgtggatat
    53701 gtagagcatg tttataatca ctcagcgatc attcgcattg aaaacacgat ggaatgtgac
    53761 aagcggttag cgaaaagcaa agagaattta gcagtggtga gattggtgga tatggaagtt
    53821 ataaaatctt aattttgctt ttttacaact atcctacaac aatgagcgtt attccacaac
    53881 tggaaggaga agaggcaatt gtgaacattt tagagaatat agatattaag caaacaagga
    53941 aaaatgctag acgattacta aaaagataca gaaatttaga acgtttggtc ggaccagtga
    54001 aaatagactt ttccgtgatg actgttacca aaaatttgaa attcacaatt gacagtcaaa
    54061 acgaagaaat cattgaagcg ataagtactc gagattcggt tatcgaagca ttaacacggc
    54121 taagtagaat ccatttccag gtactttatt atagttattg ttttcctaat aagatgtcaa
    54181 tgtatcaaat aggagaaaaa ttaggatatt ccgatagaac tatcgagaga atgaaggcag
    54241 tagctttggt tgaatttgct gaggcgtata aatcaggaga actcatttca cgtacaaaat
    54301 aaaaaaagtc ggattcctcc gactatgaat aatatttccg acataagtat tatatcataa
    54361 ttgggggaat cagaggatgg tacttttcga tgtaaagaaa tatgagacac caagcgcgaa
    54421 agatgttgat atggaacgca caaaacataa tgtcgctgtg tttctttcag catatctatc
    54481 agctagatgt agagtaggtc aacctcgaga accaaaagtg acagcatctt attccttggt
    54541 tccaccttct acagctgatc atatatttga agcagaaaga atgctgatcg ataaagaaga
    54601 agcacaggaa gaatttgagt atctgcataa attgtttgtc cgaggctatt cagcgataca
    54661 gcatccgcat aagcctgatg tgactgaaag gcgcaagaag atattctatg atcgttatat
    54721 caatggcatg tcgatttatg taactgccca aagaaataat acgagcgagg aatctgtaaa
    54781 agcagaatca aacaaaatca tcattcaatt tgcttcttcc ttagaactgg ttgctttcaa
    54841 gtagccagtt tttacacttt ttataccctt ttattaccaa tttggtttcc attttatacc
    54901 ttttttatac caatcactta cctattcaac gttgtattat gatagtgtcg aaagattagg
    54961 aaacaggatc gacaaaataa aatgtaaggg aggaaatctc cctcatcgtt taattaagct
    55021 tcgataggca gcaacggaaa tattaagaat aaggatgtga atttcaactc cttctaaatt
    55081 gttcttatta tctatcatcc gttgctgtct attaatttat gtattggagg gtaagaatat
    55141 gaaattatcg attgaaggta cttcaggaga aataaaagaa atcctctcag ctatttgtaa
    55201 tagccgagag attagcaatt taatcaatat agataattta aatgaatcta ttgttactcc
    55261 aagttcccga gagaaattgc agaaatctga tcagcaaaaa caactaaaaa tgggatatta
    55321 gtagttctct cgcctatgat ggtaacatct ttcagaaaga tagatttgac taccaaactt
    55381 tgctcatcat ctttttctat atcatcaatt ttttttgagc gaaattctgc aaaagaatcc
    55441 atcatagcat caataagagg atttactttt acttcagcat caaagtctat aggagttccg
    55501 caaattgttg ctcctccagt ttgaataata atattattgt tagaattttt agcgaagagt
    55561 tcaatatatt caatcatgtc tgaacggtaa tcatcaattt ttgccatttt tttaccacct
    55621 taaattattt cagcggacca ctcgctgata aataaaatta tacgcttagt atttattttc
    55681 acaatattaa tttatcgtaa taacttttga gtaaatagaa caaaaaacct gcactagttt
    55741 ccgctagtac aggcagtgac tatatcggtt gataatctag catatattaa aaataattgc
    55801 aagaaaagaa atttatagtg gtttatacca aattatcaaa gcaatgttat tttgttgctg
    55861 tctattgttt tttaattatt cacacgataa ctaaaggtgg gtgaagagaa atgattccat
    55921 taataatttc aatttttgcg ctctgtctta atgtctatat gattggattt aaaaatgggc
    55981 aaaataaaaa atagtagcag ccaagaataa ttttatagtg tcactgtggc ggaaagggta
    56041 gacgctaagc atgtgtgcta ggtcaatgct tcggcaacca tgcaaggttc gattccttgc
    56101 cagtgacttt ggcaaccgag gcatcggcgg tttaaaaata taggggtgcg caatttcgta
    56161 cgcgttttgt gcatcgtgta ggttgctatt acataactgg ttaggttaga ttgagatttg
    56221 ggattcggta caaatgaatc gtcaaatgtc tcaagcacag gatcggaaac gtccctgcct
    56281 gtgcattaca tattagatca ctcgttgagt ggtcttttta ttttgcaaaa aggaggtaac
    56341 aacaatgtat agaccacaat acttagaaca gaagcatgaa gtaatcactg tgcaaaacgg
    56401 taacggtgag atagtacgaa agtatagaag accaataaag agcaatacat ataaacgaaa
    56461 ggaaagcaat gaagttattc cattgtatgg caaaagaata gctaagtatt aaataagatt
    56521 gcgaaaggag atgggacatg accgaggaat tctatagatg gttattacag ttgataagag
    56581 aagatcgttt ggttaagttc tatcagtctc ctaaatggcg caggcttaga gagaaagcga
    56641 tgaaacgaga tcactatgaa tgccaagagt gtagaagact aggtaagtat catagagtag
    56701 agaacgttca tcatataaag gaagtcaagg atagacctga cttagcttta gatttagata
    56761 atcttatttg tttatgtgtt gaacatcata atgaagttca tggcagatat cttacagcat
    56821 tagataaaca agagaagaag atagaaagct ttgctaactt cgatgcaagt gaaaggtggt
    56881 aagtgcatga tcatcaatga caatggcaga gagtatgaca cagaaaagat tgaagagtat
    56941 tcatcttata ctcaaggatt aattaaacgt ttgatatacg ttcgctatgt aggtattagg
    57001 gatctgttat cagataactg ttgcagtaaa tacaaagtga atcaagtaag agaagcgttg
    57061 aataaagata ataacgttga aagaataaaa aatatttttg gatatagcat tgaagagatt
    57121 aattattaca ttgacttcgc tgaagctttc attccgatgg tgagataacc cccccttaaa
    57181 ataaatcgca aattttttgg gggtgatgaa acggaggggg ctgtcaggaa aagagatttt
    57241 ttcgaacttt atcatgaaag gagggctaaa atgtttaaaa acgaattgtc tcaaaatcgc
    57301 tacagagaaa aattacgccg ctctttaata agccaattgg aaagtcagaa aacaaatatt
    57361 gagccattct tagataatgt tgatcgttat atcagtttat gggaaacggc gatatcactg
    57421 gaagaagata tatccgagaa cggcattaga ctggagaatg gtaaaaagaa tgaatcagta
    57481 gcgttgcttg tttctgtcaa caaacaaatg ggattgatgt tggataaact tgccattact
    57541 cctgaattgg taggtgaagc aaatgaatca attcctgagt tataagcata ttgaaaattg
    57601 gttcaaagct atagaagaag gcactatcaa ggtatgcaaa gagcaattat tgctaaaaaa
    57661 ttatctagaa gaaagagtct ttactagaga agatatttac ttcgataagc agatggtaga
    57721 ggattcaatc aatataccag cacaatactt tccattcgaa ttaattccgt gggaaaaatt
    57781 tctacaatgt tttatttatg gtgttcgatg gaaaaaagat aaaacgctag tgttcaatag
    57841 atatctttca ttaatgggac gtggtaatgg taaaactggt tttgcttctt ggaacaattt
    57901 tttcttgctg actgcaaaac acggtattaa aaattatgat attgatatct atgccaataa
    57961 cgaaagccaa gcaaagacta gttttgatga tgtatttaaa gtaattaaag atcatcctgg
    58021 tttagataaa aaagtattta aagctacgaa ggaagttatt caaaatatcg ctacaaacag
    58081 caaacttcgt tataacacgg caaacgctag aacaaaagat ggtaaacgac caggagcaaa
    58141 ccgctttgat gaaattcacg aaaatgaaga ttattcaatg ataaatgtag ctacttctgg
    58201 tggtggtaaa attcgagatt atagagaatt ttatgataca actaatggtc atgttcgtgg
    58261 tggtccgctt gatgacatta tagaagaatc aaaaatgatt ctttctggag aacttggaat
    58321 tgacaaggat ggagcagaat tttctagttt gtttccattt atttgtcgct tggataatga
    58381 taatgaagtt gatgatcccg atatgtggga aaaagcttgt ccaactatta attacaatgc
    58441 agatttaaaa cggaaaatgt ttcaagaata ctctcaaatg caacgtaatg ctggtttaag
    58501 acttacgttc atgacgaaac gaatgaatag accaatggaa gatacgcgat ttgctgtagc
    58561 ttcatatgat gatgttcttc atacgaaaga aaaagaattt cctgaaaaaa tggatgaagt
    58621 gataggaaca gttgattttg ctgatagacg agattttgcc agcgttggtt tgttaggaaa
    58681 atatgataaa gatgtgtatt ttacacaaca tacttttatc cacgaatcag ctcttcgatt
    58741 acagaacata aaacgagagg ttatagatat ttctatagat caaggaaaat cacagatcgt
    58801 tcatgggaaa aatatagaag ctgattatat tgtaggttgg tttcttgaaa tgagtaataa
    58861 atattacatt aaaaaaatcg ctatggatat gtaccgtgca aaaatattga agcccgcttt
    58921 agaagaagca ggttttactg tagaaattgt tcgaagcgga tctgttacac atggtatgtt
    58981 aaaagaccta gttgatgacc tttttattaa tcaacgttta ttttttggtg acgatgcgat
    59041 tatgcgttgg tattgcatga atgtatatga agagcatatt tctaatggaa atatacgcta
    59101 tgaaaaaata gaacctgaaa ctagaaaaac ggatggcttt ttttcattcc ttcatggttt
    59161 gaatttttta gatgatattt atgattctgc tcctgtaaca gtcacaaata gttcagtaga
    59221 aaatgcagga actggattta ctcctctagt attctaactt gaaaggaggt gagaaagtgg
    59281 ggatttttca aaaggcggta ggatacttca caaaaaaagc aacggttcct ttagaagaat
    59341 acttttgtaa attgcaagtt gattttgtgt atcgaaaatt tgcaattgaa acttgtattg
    59401 atttgattgc aaatgcgatg agcaaagcgg aattcaagtc atatgaagat gggaaaaata
    59461 aaaagaatga tctttactat aggctgaatg tagctcctaa taagaaaaat aatgcaacag
    59521 aatttagaaa aaaactgatc aggagattaa tattctacaa tgaagtattg atcgtttctc
    59581 cgtctaataa ttctagcgaa atatttattg cggatagttg ggatgtcaca gagtatgcat
    59641 taaaagatga tgtgttttct caagtgcaaa ttaacaacat agtccttgat agagaatttc
    59701 tagaaagtga tgttatctat ataaaatacg cagatcaaca aattaggcaa ctagtcgatg
    59761 cgtattatca agcgtatggg aaactcattt ctagtgccat gaatgtttac aagcgttcta
    59821 acgctcgtag atacgtactg aaagggaatt tattccgagc gcaagacaat acaacacaag
    59881 atcaaatcaa taaaatgatg acatcacaat ttaaggcttt tatggaagct gataatgcag
    59941 gtgcggtatt tcaattacaa aatgagtaca aattagaaga tttcagcgga aactttcaaa
    60001 gcaattcaag agatataaaa aacttaatag acgacatctt tgagatgaca gcagcagcgt
    60061 ttcacgttcc gaaaaaccta ctaaagggag acatgagtgg attatcggat caagtggacg
    60121 cttttttaat gtttgaaatc ataccgattg ctgaacttat tcaggatgcg tttaacgcta
    60181 gtctctatga agtagaagaa tacttgtcag ggaattttgt acgtgtggat acaactatga
    60241 tcaagattac tagcttcaaa gatttggttg acgctattga tgtaggcatt agaaatgggg
    60301 tatttacaat caacgaagga agagaacgcg ttggaaatga tcgctctgat aaggcgatgg
    60361 cagatgaaat atttataact aaaaacaatc aacaagtatc gaaaggaggt gaggcgaatg
    60421 acgacaatga aaacatttct agcagtaaag aatgaaggcg cagtaccgca aatttttatt
    60481 cagggattta ttggttctag ttggttcttt gaagggaata ctgacaaggg aatcaaaaat
    60541 attttggata gtctaggtga tcaagaagag attgaagtag taattaattc aaacggtgga
    60601 gacgtatttc aagggattgc tattgggaac ttacttaagt caaataaagc aaaagttaac
    60661 gttgtgatta acggcttagc cgctagtgct gcttcaatta tcgcaatggc tggcgatact
    60721 ataaaaatct acaacaatgc acaattgatg attcaccgcg cttccacata cggagaagga
    60781 aatgtcgatg acttccgtac gattgctgac caactggaat caattgataa atcggtaaag
    60841 gcttcatata aaacacgatt caatggcaca gatgaagcat tgcaagaact tcttgaaaaa
    60901 gaatcgttta tggatgcaga aacagctttg agttatggat tggtcgatga aattatcgat
    60961 gcagaaaata gctcaggtac tgaagctaaa aaagaacaaa gcgttgaaga aattttgaat
    61021 gacgttaaag aaaaaagaga agaaaaaatt gctgcattta cagcagcatt aaataaaaca
    61081 tttggacaag gagatgtaaa ataatgacag ttaaaaattt aaaaggtgta acagctgcaa
    61141 gcgaccaatt gatgaaagct tttaaagatg gtaacgaaga atcttttagc gcagctatgg
    61201 taagcttatc taaggaaatt caggataaaa ttttagaaga agcaacagca aaaaatcaag
    61261 atcaattagt attaatgaac cgtggtcagc gtgtattaac tacacaagaa acaaaattct
    61321 ataacgaagt agtgaaaaac gaaggttttg caggggttga agaattagtg ccagctactg
    61381 tatttgaacg tgtatttgaa gatttagaac aatctcatcc actattgcaa aaaattactt
    61441 ttgttaacac aactggtgta acagaatgga ttgtgtcacg tggagtcaat ccagcatggt
    61501 ggggtaaact ttgcgaagct gttaaaaaag ttttagataa tggctttgat gtaattaaca
    61561 tgaagcagtt caagctatca ggttatattc ctgtatgtaa ggcaatgctt gatttaggtc
    61621 cagtatggtt agatcgttat gtccgtactg ttttagtaga atcattgaga attgcattag
    61681 aacaagcaat tgttgatggt actggtaaag atatgccagt cggaatgatg cgtgacatga
    61741 gcaaacaaac tagcggagaa tatgctgaaa aaaaagcaga acctattaca gctttagatg
    61801 ctgtaactat gggcggtttg atggcgcgac tatcaaaatt caatatcgaa ggtgtgaatg
    61861 atccgattta tcgtaatgtg aatccttctg atgtggtcct aattgtgaat ccaactgatt
    61921 actggtctaa agtattccca gctaagactg tactaactgc taatggagaa tacgtacaag
    61981 tattgccagt accagtttca gatttgcagt caacggctgt gccagaagga aaagcagtta
    62041 ttggggtagc ctcagattac ttcatgggtg taggatctac actaaaaatt gaagcttcag
    62101 atgaatacca ttttgttgaa gacgaacgca tttatctagc taaacaatat gcaaacggtc
    62161 aacctaaacg taacgatagt ttcattgtat tagatattag cgctttggga actactacta
    62221 caactacaaa accaacaacc acaacaacta caacacgagc gtaggtgatc agaatgaagt
    62281 atattctttg tcagccggca atcaatcggt ttaaatggga gcttgaagtt tgtttaacta
    62341 atctgaagaa actaggaatc aaagatatcg tattgctttt cagcagacac gatgatcaga
    62401 ttcctatttt ttttgagaag gaatatggtg ttgaagttca tgtgtacgat gatctgcggg
    62461 acgacaaaga gtatattcct tcgattaaac catatttatg gtggaaatat ttagaagaag
    62521 atcattcgcg tgaggacgac cgatatttct atatcgattc ggatgtcatt ttcaataaaa
    62581 gaattaattt gcgcaaattg ccttctaaag atgatgtttg gtattgtagc gactgctgta
    62641 gttatctaag tcttgattat attagaagct gtgaaaacgg agaaaatatt ctaaaagata
    62701 tggcaaacat tgtaaatgtt acagtagaat ctttggaaac tataaacact aattcaggag
    62761 gcgcacagtg ggttattaac cgtcctaaag cgaattattg gaaaaaggtt tatctggatt
    62821 ctaatcggct atatcgctac cttagagggc aaaaaacaaa tatacaaatc tggacagccg
    62881 agatgtgggc acagctttgg aacatgatgt atttcaatat tggtcctaaa gttcacgagg
    62941 aattagactt ttgttttgct actgatccaa tagaaaaagt taaagaagta aaaatcttac
    63001 acaatgctgg agtaacaaca aacgatgaag atttattttt caaagggaga tacgtgactt
    63061 ctacgccttt tgatgaagat ttatcatttg taaacaagaa aaaatgctct tacgcatatg
    63121 ttaaagcaat taaggcggtg gttagatgac gcctgaacaa gtgactgaag aattgctaat
    63181 agctgtgaag gataatattt acgttacctg gaacgaagaa gatgagtcaa ttaaaaagat
    63241 gatagctaaa aatgctgttt atcttcaaag taaagtgagt acaacacttt ctttttctcc
    63301 tgaaagctta gaatacggat tgctaatcga aagatgtaga tacgactgga atcgtgcttt
    63361 agatgagttt gaacaaaatt tcgctagtga gttattaggt ttcattcaac attatgcgct
    63421 acaagaatat attgcaggtg atgtgaatgg cgaataatcg tagactcgaa gaaacattca
    63481 acgatggttg gttaaagatt ttgacgcaaa ctaccaaaag aaatgaacta ggaaaaaaga
    63541 ttggtgtaga agatacagaa atcacttctt taaaatttag aaatctttcc atgagagata
    63601 gtgatataac agctatggat gcgatgggat cgaaattaac taagaaagta aagactccat
    63661 ttcatccaat cgccaagaaa tttaataaag atcaatattt tatcgtaatc gatagtatgc
    63721 gttacaacgt tatctatgcc gattacgata atttttatat ctatttttat cttgaaagtg
    63781 tgggtgaata tggtgattga taattctaaa gaaaaagaac gtttaaataa gcaaatttct
    63841 gctatcaaaa cttccttaga agagcatttt ggcctcaaac tctttcaaga ctccgtaggc
    63901 gaggatgagc tacctgatga ttttaattac ttcattctcg aaacaggaga aatagaaatg
    63961 atcactgagc caaaatatag cgtgggtcaa aatctatatc taactttcta ttcagaaaat
    64021 agagaagatt taacaggaga ctcactagat attatttcat tgattcaaaa tcgttcgatt
    64081 cgttttcaga gaatggatcc caatcattta aaactagaga accaagatcg ctatatcgat
    64141 caattggtat ttacgtttag acgattattg aagagtgatt gtcatggcta aaaatagttg
    64201 ggagctaaaa ataaatggac atgatgaact tcttgtgcgg atggaacgct attcaagcga
    64261 gagcgaacga ctgattaacg aagcattgaa atcaaaaggt tcggctattg cagtggatag
    64321 gattacagaa aaaattcctg tttctgaagc agatttaaga agagggcacc aacacgcaaa
    64381 aaatagtcgt ccacttaaga ctcaatacat taatttgggt ttcatcatta gacctacaag
    64441 aaaatttgag tatttaaaat atcctgattt ggggataggt acttctaaaa gaaatcagcc
    64501 ggacgaattt atgagaagag gattaggtct tgcacttgat ccaattacag aacttctgat
    64561 tcgtcaattc gataaattaa ataaataggg ggaacaacaa tggctaaaac aaaaactgta
    64621 gtaacaacgt tcgataacgt aagtatcaaa cgaattgctt ttaattttaa gaacgcagga
    64681 aatgcaatcg caacgaattg taacggacaa ttagatggcg aaacagaaat gcaaacggtg
    64741 gttaaaaaat gtggagcgac agaagtaaaa tcaaaatcta aaccaatcaa tatgacggta
    64801 acaattactg cacatgtacc gatggaagtt tatcgacgtt tcaatgggtt gaaacaagat
    64861 ggacgtatta aaccaggcat ttactcttac ggtcctgatt ccgtaggcga agatttctca
    64921 cttgctgcag agatcgtgga tgacttcgaa gaaaatagaa agttagttgg tatgttagca
    64981 tgcacttcga atacaggatt aacattctct attgaaaatg gtgcggatga agtagctgcg
    65041 ttagaactag aaacaaaagt tatgcaagat gaatttggta aattttatca tgaagcaatt
    65101 gttgcagaac ttgaagaaga cttaacagat caatggatga cgaatctatc tgctgatgtg
    65161 attaaaaaaa cttcagttgt gacaactacg gccactcaat cacagtaaaa aaaacggagg
    65221 tagcgaaatg aacgaagatt actcaaaaat tgaactaaac gatggaacaa ttttgaattt
    65281 agaacctaaa ctgaatatca agaaattatt gatgatcaat agagatttta acacagacga
    65341 gtttgcaaaa atgactgtgg gaaaaggatc catggatatt tctgttattc aaggtgcaaa
    65401 ggctgtgtat attgcttacc gccaagcgaa catgactgat tatatttcat tcgatgaatt
    65461 tatcgataaa tgggattttg atatggctac tgccagctat atttatcaat tgatgatgtt
    65521 caaacaagca cgcgatgctt atcaaaaaga atttgaaaaa gcaaataagg aaaaaaagct
    65581 tcaaaagtaa aaatgccaaa gctcttagtt gaaacgtggg tcgatgtcta ttcgatgttg
    65641 accgacgttt tttctatgcc ttcagatttg gttttaagcg atatctgttt agatgacatt
    65701 ttgcaaatgg cttacaacaa gagtgcttat gaaggatgga aaaactatgc aataaaccaa
    65761 tctcagaaaa actaaagaaa ggaggtaaaa aatggctaaa aagagaacag aagcagaagt
    65821 aactttcata gctaacgatg acggattgaa atctacgtta aaagaaatca gtgctgaatt
    65881 aactaaaaat agagcagaat taaaactaga acaagctcaa ttacaacaga ctggttctga
    65941 atcagacaag ttaggaagta aattatcttc tttagaaaag cagtatgaat tacaaagcca
    66001 aaaagttgaa gtaactagcc aacgtttagc caatgccaaa aaatattatg gagaaaattc
    66061 caccgaagtt cagaaacttg agagagaact gattaaccaa caaacagcgc aacaacgttt
    66121 gtcaaacgaa attgataaaa cgagtaatgc actagctcaa gcaaaaggcg aaatacagac
    66181 gtacgagtct acaatgcaac agttggatag tgaacaaaaa aatgttcaag ctagtgcttc
    66241 tctgattgaa tccgaataca aaaaatggca agtaactgct ggtcaatcag cttctgaatc
    66301 cgagaaatta gcgaaagccc aagaatatgt ttctcaacaa tctgaaaatg cagagaaaac
    66361 gatagatatc ctgagacgac agttagaagc tacacagtct gagtttggcg ctacatccac
    66421 agaagcaatg cagatggagg cgaagcttaa tgatgctgaa cgtgaatttg aagagttagg
    66481 acaagctgct aaaaatgtag atacaactaa cttggacgat atcggaagca aaatagatat
    66541 gaataattta atggaagctt ctgacgtttt aagcgacatt ggcgataagc ttacagaatt
    66601 agggaaacaa gcagtggact cagctaacag tgtaggtagt tcccagagta agatacaagc
    66661 taattttggt ttgactaaac aagaggctga agaattaacg aatgtagcca gagacattta
    66721 ttataaaggt tttggagaat cgttagatca gtccacagat gcattgattt tggtaaagcg
    66781 taatttaggc gatttaaata atcaagattt acaaaatatc acggaacaag ctatggtcct
    66841 agaaaacacc atgggcgctg atatggatga aacgttacgt ggtgtaaatg gcttaatggt
    66901 caatttcggc ttgagtgctc aagatgcaat ggatttaatg gtttcgggta ctcaaaacgg
    66961 tttagataaa acgcacgaat taggcgacaa tatggcagaa tatagccaat tatggagtca
    67021 aatgggatat tcagctgatg aaacgttcgg aatgcttcaa aatggtttag atgcgggtgc
    67081 ttataacctt gataaagtca atgacttagt taaggaaatg ggaatatcgt taacagatgg
    67141 tcgatttgag caaaacatgg atatgtttag tgaaagtact agaaaagctt ttgaagagtg
    67201 gaaaaatggc ggaggaacac aaaaagacgt tattaattcc atgattcaag attttagcaa
    67261 tatggatggt caatacgacc aattaaataa agcttctaca atttggtctg cacttggcga
    67321 agataacgcg atgaaagttg tccaatcttt gactgatgtt aaccatacat ttgatgatgt
    67381 tagtggatct gcacaaaaaa tgaatgaaga ttctactact ccgttacaag aattaaacgg
    67441 aaaaatagct gaattaaagg attcattagc tcctataggc aacacaatca tagatgcact
    67501 cgaaccagta attgattttc taggaaagat ggctgatgcg tttaataatc ttccacaacc
    67561 agtacaggat tatgccgtag cgattggcgg attgactgct gcatttactt tattaatgcc
    67621 aataatagtt ggcttcatgg ctctaggtgg tcctactaca ttaataatag gagcagttat
    67681 tactgctatt gctggagtta tagcaattat aaaaaactgg ggcgcaatta ctgactggtt
    67741 taagggaata tggagtaaat tcactgattg gttgggtggt acttgggaaa gcataaaaga
    67801 aggtgcctca tcagtttggg atggagtcaa agaaacctgg tctggatttg tagattgggt
    67861 tcaagaaatt tggcaaggag tttctgattg gtttggagag ttatggagcg gattagttga
    67921 aggagcttcc aacatctggc aaggagtcca agagacttgg caaacattca ttgattgggt
    67981 ttcaaatatt tggaacggag tcaaagaagt atggtcgatt atttgggcag acattgtagg
    68041 aattgttcaa ataccatgga cattaataac gtcattgatt caagctggta ttaatattat
    68101 cgtgggtatt tttgatgtag ctggacagtt attaggcgca gcttggcaag ctgtttggac
    68161 acctatttct gatttcctta aaaatacttg ggatactatg acacaatgga taagcatcgc
    68221 ttggaatgga attgtaacta cattccatac tatatttgat ccagtagtgg catggtggaa
    68281 tggtatatgg acatctatta gtactacggc ttcaaatatt tggaactcaa ttagtgcaac
    68341 agcttctagt atttggaata gtatcaagaa tacaatcact agcttggtac aagcagttgc
    68401 tacagtaatt caaaatattt ggtcaactgt atctagttgg ttaggtggaa tttggaattc
    68461 aatcagctct acagcatcaa atatctggag tagcgtgact agtagtataa gcaatgctat
    68521 aaacgcagct aaaagtgcca ttcaaagtgt ttggaatagt atatcttcgt ggatcagcgg
    68581 aatttggaac ggtatcaaaa acactgcttt gaatctttgg aatggaatta caagcactat
    68641 tagctctaaa gtaaacgatg gaaaaaatgc aatttcaagc ggttggtcta atctaacagg
    68701 tattgtttcc gacatattca ataatgttaa aagcacgata gctaatatat gggaaggtat
    68761 caaaaagact gttagcgctc cgattgattg gattagagat aaaatcagta gtgtctttga
    68821 taatttgaat atttctatac cacatattcc gttaccacat tttaaattga gcggagaatt
    68881 caatccattg aaggggaaaa tcccaacatt gggtgttgat tggtatgcga aaggtagtgt
    68941 gtttaattct ccaaatatta tcggtgtcgg tgaagcagga cctgaagcag ttttaccttt
    69001 gaaaagatct gtgctgcaag aaattgggga tcgtatcttg agtagcacct cagtttcatc
    69061 tagggcacaa acgattcaac ctgtgaacaa ttacgaattc aatttcacaa ttgatggtaa
    69121 cgcagatgaa gtcactatga agcaaacaac tcaacaaatc attgatagca ttacaaaagt
    69181 tcaaaatgat aatgcttcgg catggcgtta aacaggagag tatttctcct gtttttttag
    69241 ttttaaaaag gatgtgaaaa aatgactgat tgtatacatt ctataatcga tggatttcct
    69301 gattatttgc ataaattggc tttagcggaa agaccaacca taccttctcc aaaaagacag
    69361 agagttgaaa cttctgtttt aggacggcta ggtggcttag tacaagatta ctcgtttgaa
    69421 gacatgtcgt ttacattgca ctataactat ttagaagatg tggaagacca tcaagcattc
    69481 aagcaatcgt tttatatcat gcgtcattgg ttaaactatg caaagaaatt agaattctct
    69541 gatgatccca acgtctatta tgttatccag actatcgata ttggggatgc agaaaacgat
    69601 attgttgaat ggggagagtt cgatgtaaat atcactgcga aaccattcgc aagagttcaa
    69661 gaagatgtac ctataaccgt agataaacca cagtcattta acttgctgaa taatagttta
    69721 gaagaaagtt ttccaaagat tatcatcact ccttcagcta cttcatgcca gttcatctta
    69781 aatgattatg tgtttagttt tgaaggctta gtagtaggaa ctgatgtagt cattgatagt
    69841 gatttaatgc tttgctacga agagcaatcg gacggagata ttttagatcg gtccaacaaa
    69901 atgaagacca tgcaatatcc aacgttgcaa gtggatatta atcattttac ttgtactggt
    69961 ttgagcaaaa tacaaattta tcgtaatggg ttaaggtagg tgaaatagat gatcgataat
    70021 ttactaacta tttacgataa aaatgacgcg aataatttag ctgaacattt atatgatacg
    70081 caaggtttag gcgctttgtc agactggtta acagctactg ttagcaataa actaaacgga
    70141 gccgagatat ttcagggtac ttattcaata aacggaacta atgcagattt gattgtagaa
    70201 ggacgtatta ttcagtgtta tgtagatgaa aatcgagcaa aacagcgtct acggatttat
    70261 tatgcaaaaa cttctgtaat aggcaatacg atagaagtaa aagctgaacc tattttcaat
    70321 gatataagaa aatcggtgtt gaataaatat gacagcggaa cagaaaaaat cactgctact
    70381 caggcatggc aaaacgcaaa agttttagcg aaaccagcta tcccttcgca gttttctttc
    70441 tcgtcattag tagatacgct tgctaatgtg aagatagaaa aggcgaattt tttagaattc
    70501 tttggtggaa aagagggatc tattctagat cgatttcatg gtgagtttct aaaagataat
    70561 aacacattac gtcatgaaaa aagtctaggt acggatcata aaatcaaagc gatttatact
    70621 aaaaacttaa ctggtcttga cttagagatt gatgctcaaa gtgttttagt tggagtttat
    70681 ccatttatta gcagctcttc agaaggagaa gacgagatca ctctaccaga agaagttatt
    70741 ttcacggatt acgtggatga ttatcctgct ggatatgttt cttttgttga ttttaaagac
    70801 aaagcgactg atgtagccac attaagggaa gctgctaaag actggttgaa aacaaacata
    70861 gataaacaaa aaccacaagt gagtggttcg attgaattag taccattgag gcatcaaaga
    70921 ggctatgaaa aatttgttga tctagaaaaa gtttcgatgg gtgacggagt agatgtgtat
    70981 catccacagt taaaagtgaa tatgtcagcg agaattgtgg aatatacgtt taatgttcta
    71041 accaattcat acgataaatt agttgtagga aacgtcaaaa caaacttctt agaaaacaca
    71101 gagaataatg tcagcaattt gattaatgat gccattgatc aattgaaaaa cgttggcgaa
    71161 atcagtgatt taatcaatga tattgtagat catcaaactg atatgattac tggtcaaaat
    71221 ggtggttatg ttttattaga tcctaaagaa gcgcctagtc gtattttgat tatggacaca
    71281 ccagataaga ataccgcaag gaatgtttta caaatcaaca atgctggtat tggtttttct
    71341 aaaactggca ttaatggaac atatgaaacg gcatggacgt tagatggcgg attcaatgcc
    71401 tcgtttatta cggctggtga aatagtagga attactatta gaggtactac attaattagt
    71461 gatggtgctg attatagaac aagtattgct aatggcaaaa tgacttggta ctcaaaaaaa
    71521 gttaacaaag atattatgga gctagaagca cgtgattatg taagtgctga tgccggtatt
    71581 gtatcataca ccatgaaaac tggtggtggt ttcatgatta gaaatccaca gggtaacttg
    71641 gtttttagta cgtgggataa tggtaataac agaccgtttc tatcttttgg tgcgcccaat
    71701 ttcaggtata gcaatgctag ttatgtaact tctggcgacg gtagttcttt aagcattaat
    71761 ggtagtgcgg gtaactcatg ggaatttaag gtagctggta ggactatgaa atttactagt
    71821 gatggtatgc taacgttacc aggttgtttt tttggttcat gggaagatgg gaaacttgct
    71881 aggtttgaac aatcaacggt acaagtatat aaagatttta ctgttagagg tactaaaaac
    71941 tcaactgtac caacagaaca ttatggacaa cgactattga acgcttatga aactccagaa
    72001 tattatttcg ctgattatgg ggaagccgtt acaggtgacg atggtaaagt tcgtgttgat
    72061 attgacccca tgtttgctga gacagtaaat ctaagtcggt atatgacaca tgtgacacct
    72121 acagaactag ttttgtgtgc tgttactcat gaagatattg accatttcat cattgaaact
    72181 agtaagccaa acgtattagt tagatggaat ttagtggcac accgtctagg gtatgaagat
    72241 attagattaa aagaggatac agcatatgat agcacagtgc ttgaccaaaa acgtttttaa
    72301 aacgaagaca aggaggtata taaatggcta gcagtttata taatttggct ttagatttca
    72361 gcaaagaatt aaactacacc aaagctatta tggctcgtca gggtgataaa gggattacgg
    72421 tgacggttaa accatattta aatggcttgc agatggatac gagtggcgga acatttactt
    72481 taaaaggaac aacaccatct aaccgttacg tagataatgt tgcaactagc gtaactagtg
    72541 aagaagtcac gttttctctt gatggcacat ttatgagtga agcaggatat tataaacact
    72601 gctacgtaga atatagaaaa gacaatcaaa ttctaacaac gcaagatatc atttttttct
    72661 cactaggagt gtctgacatt tcgcaaggtc aagccgatga atatgtttcg caattagaag
    72721 agttgattcg aaagtataat gaaacttttg atgcttttat ggctgaaact aaaggtagag
    72781 tggatagctt aaatcaacag attactgatt taactggtca agctaaaacg ctacaagaca
    72841 agttagatgc tctgaaagaa gaaatttcta agttaggtaa cttacaagtg atgtacagta
    72901 acagcatcga tttcgggaac tatgattata gtgggaatcc taatttgtta agtaagctat
    72961 catacgactt aattgaaaat caaaatactt cagctggaac actttctaaa ggtgaaaact
    73021 cgtttaaata taataagata tcagctgaaa cggaaggtgg agtagagtta tattataaac
    73081 gaagaggtat agctaactgg ttaccctcta ataaaacgct tgtaatgacc gttaaactta
    73141 gagctggagt tgactatagt ccagctgacg gaaaaaaaat actgattaga tataggtttg
    73201 ttgacaatgg aactggcaag attgttttag acttacctat taacagtaat tcgataactc
    73261 aggaatggaa agagtttagt attactggaa ctactccaac atttggcccg caagcatacc
    73321 atccttggat acaatttagg gctcaagatg ggatacttgg ggaaatagaa atgagctatg
    73381 acatcaaaat cgaagaaggt ccaacagcca caccgttcca acctaactta ttggcagaac
    73441 cttataacat gtgccgcgag tatcctaacg agaacattgt caatcctaca gttaagttcc
    73501 caattaaaac atcaaataat cctatttctg gttttgatat ttcagaagaa ttaataatag
    73561 gtgaaactta tacggtatct ttaaaaggga ctaagccagc tactaaagaa ttccacttat
    73621 actacggaga agcaaattac cagcagttgc agcatcaggc aactttactt cctgtggaag
    73681 gattaacaga tgtgtggagt gccactttta cagccagaaa tactagtgaa acgacaaatt
    73741 tacttagagt agcgttatgg caaaaaccta attctgcaac atatgatact gttcaaattg
    73801 actggctcaa gattgaaaaa ggcaacaccc gaacgcccaa tattagtgag tataaatatc
    73861 gtggtactgg tatgcgtgat tcaaacaatc caaaagatta tgtttgggat ctagcaccag
    73921 aatatgtcga agataatttg gccacagata ttaaaatttc tgaaattact ggtaaagcaa
    73981 acaattatac cgatgggaaa gtatcggaga ttaattcgca gttgactgct tcaattaatg
    74041 aagtagacac cacagctaag gatgctcgaa caaaagcgaa tgctaatgcg actgctatag
    74101 atgaattaga caataagatc gatgaacgca ttaatgatgc agctactacc gcattttatg
    74161 gcgcacaagg tgaagtctct aacaaaacga aagtagcgga gtatggagta ggaacagggt
    74221 atactactac agctgtagga gaaacacatt tcgaacgtca atctaacgga tacgttaaat
    74281 gcttaaaagc tggtaagtat tcaattagtg cgcaaatacg tgtgcaattg ggcgggaaat
    74341 atgcttcatg gttatatact gatttatata aagatggaac ttctgttgat aatttagtat
    74401 cttatggggt cgacgccttg caaaatagat ttgcagctag cggaaacatt gtaactgatt
    74461 tagaagtaaa cgatgtacta aatatgcgta ctgaaatcgg cgttgcagat ggaattttac
    74521 aatttacatc ttgccgtact ttagtcttga ctagactatc tgattaatac aatatttata
    74581 attttgctat caacacgctc aaaggagggt gttttttatt ttgcaatgaa aggaggctag
    74641 ttggttgaaa gacgaagcaa tacaagacgt ggtagaacgc ttagtgcgta ttgaaacgaa
    74701 actggataat tacgaattat tacgtgaaaa agcggaaagt gcaaaagata gagcggatca
    74761 ggtatattct attgcgctta ataatgcaga agacatcaaa gaaatgaaag ccaataataa
    74821 atggtcgtgg ggttacatga ttggtttagg cattacgatc attggctatt tcttgactaa
    74881 attgtaaagg aggtgagaag aaatgatttt accagataag tattatcaag tcattaaatg
    74941 gacagtttta acagtattgc cagctgcatc tgctttagta gccatgttag ggaaagcgta
    75001 tggatggaat ggaacagata tgatagtgct gactatcaat gcagtagcaa catttttagg
    75061 cgttatcact ggtgtgtcgg cttataattt gaaaaaatag gaggaaacaa atgaaaaaga
    75121 aaattactat tactgcgatg agcctgttaa cggctctttt tttattgcca attaacggat
    75181 ttgcctatac tatcaacaat gaatttaatt tgggcgcaaa tgaaggtagc tcacaagtag
    75241 caaataatca gtacatttta ctgcatgaaa cggctaatga aacagcaaca ggacgcaatg
    75301 aagcgcagta tatgcaacgt tcatggacta gtgcttacac tgcttacatt gtgggtgatg
    75361 gcggaattgt ttaccaagtt ggacaacctg gttatgtaca gtacggtgct ggttcgtatg
    75421 ctaatgccaa cagtcctgtg cagattgagt tacaacacac acatgataaa gcaacgtttg
    75481 agaaaaacta caaggcatac gttgaattgg ctagagattc agcaatgaaa tatggtattc
    75541 cattaacgtt ggacactcct tataaccaac cgggaatcaa atcgcattta tgggtaacac
    75601 aaaacatctg gggcgatcat acagatcctt atggttatct ttctgaaatg ggcgtaagta
    75661 aagaaaaatt agcatatgat ttagctcatg gatttaccga tgaaaatccg acaacttcag
    75721 atgataaacc agtcattgat ccaactagag caggtgcagc aaatcctacg ctgacagatg
    75781 gaacaaatta cgcccacatt gatcagtttg gggaaatcga aaacgcaaac ttgcatgtgg
    75841 ctggatggca cattgctaac tataaatacg agtatatctt cattatggac tacaatactg
    75901 gaaaagaact agctagagta agagctgatg ggatttatag accagacgta aatcaagctt
    75961 ataatacttt aggaaatgtt ggctatcatg tatctttcaa tatgcgtaat tttcctaata
    76021 agaaagtcta tgtaatgatg cgggcaacga atgatccaga agggaacact aaaggcggag
    76081 cacaagattt tcatgataaa cgctggtact tgaatattcc taaacgataa aaatagcccc
    76141 tc
//
LOCUS       DACDLM010000004        72434 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.004, whole genome shotgun sequence.
ACCESSION   DACDLM010000004 DACDLM010000000
VERSION     DACDLM010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 72434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72434
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.004"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(161..445)
                     /locus_tag="IV356_000266"
     CDS             complement(161..445)
                     /locus_tag="IV356_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013994.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(463..1353)
                     /locus_tag="IV356_000267"
     CDS             complement(463..1353)
                     /locus_tag="IV356_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HAP9013995.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(1373..1591)
                     /locus_tag="IV356_000268"
     CDS             complement(1373..1591)
                     /locus_tag="IV356_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013996.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(1561..3261)
                     /locus_tag="IV356_000269"
     CDS             complement(1561..3261)
                     /locus_tag="IV356_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HAP9013997.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            3528..4301
                     /locus_tag="IV356_000270"
     CDS             3528..4301
                     /locus_tag="IV356_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9013998.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(4382..4951)
                     /gene="thiT"
                     /locus_tag="IV356_000271"
     CDS             complement(4382..4951)
                     /gene="thiT"
                     /locus_tag="IV356_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HAP9013999.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(5017..5119)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(5125..6096)
                     /locus_tag="IV356_000272"
     CDS             complement(5125..6096)
                     /locus_tag="IV356_000272"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAP9014000.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(6190..7563)
                     /gene="glmU"
                     /locus_tag="IV356_000273"
     CDS             complement(6190..7563)
                     /gene="glmU"
                     /locus_tag="IV356_000273"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HAP9014001.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(8066..8884)
                     /gene="purR"
                     /locus_tag="IV356_000274"
     CDS             complement(8066..8884)
                     /gene="purR"
                     /locus_tag="IV356_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HAP9014002.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(9051..9875)
                     /locus_tag="IV356_000275"
     CDS             complement(9051..9875)
                     /locus_tag="IV356_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAP9014003.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(9848..10528)
                     /locus_tag="IV356_000276"
     CDS             complement(9848..10528)
                     /locus_tag="IV356_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAP9014004.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(10551..11489)
                     /locus_tag="IV356_000277"
     CDS             complement(10551..11489)
                     /locus_tag="IV356_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HAP9014005.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(11734..12585)
                     /locus_tag="IV356_000278"
     CDS             complement(11734..12585)
                     /locus_tag="IV356_000278"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HAP9014006.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(12739..15312)
                     /gene="mprF"
                     /locus_tag="IV356_000279"
     CDS             complement(12739..15312)
                     /gene="mprF"
                     /locus_tag="IV356_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAP9014007.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLP
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            15453..16259
                     /gene="proC"
                     /locus_tag="IV356_000280"
     CDS             15453..16259
                     /gene="proC"
                     /locus_tag="IV356_000280"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HAP9014008.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(16338..17894)
                     /gene="rny"
                     /locus_tag="IV356_000281"
     CDS             complement(16338..17894)
                     /gene="rny"
                     /locus_tag="IV356_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HAP9014009.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(18305..19354)
                     /gene="recA"
                     /locus_tag="IV356_000282"
     CDS             complement(18305..19354)
                     /gene="recA"
                     /locus_tag="IV356_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HAP9014010.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(19463..20704)
                     /locus_tag="IV356_000283"
     CDS             complement(19463..20704)
                     /locus_tag="IV356_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HAP9014011.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(20944..21522)
                     /gene="pgsA"
                     /locus_tag="IV356_000284"
     CDS             complement(20944..21522)
                     /gene="pgsA"
                     /locus_tag="IV356_000284"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HAP9014012.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(21731..22615)
                     /locus_tag="IV356_000285"
     CDS             complement(21731..22615)
                     /locus_tag="IV356_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP9014013.1"
                     /translation="MAFETIGEKLRQARLNKKISLDELQQITKIQKRYLEAIDNDDFD
                     QLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQPETVSTSRKAMHQ
                     EESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDTASSLKVEGSVEES
                     SSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITDATKPVTLEFTAVN
                     RVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNATIKANGESVPVNP
                     GENNQSPKNVNLTLQYAE"
     gene            complement(23393..24679)
                     /locus_tag="IV356_000286"
     CDS             complement(23393..24679)
                     /locus_tag="IV356_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAP9014014.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(24672..25940)
                     /locus_tag="IV356_000287"
     CDS             complement(24672..25940)
                     /locus_tag="IV356_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAP9014015.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            26192..26653
                     /gene="mscL"
                     /locus_tag="IV356_000288"
     CDS             26192..26653
                     /gene="mscL"
                     /locus_tag="IV356_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HAP9014016.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(26712..27158)
                     /locus_tag="IV356_000289"
     CDS             complement(26712..27158)
                     /locus_tag="IV356_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP9014017.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(27251..27496)
                     /locus_tag="IV356_000290"
     CDS             complement(27251..27496)
                     /locus_tag="IV356_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014018.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(27611..28189)
                     /locus_tag="IV356_000291"
     CDS             complement(27611..28189)
                     /locus_tag="IV356_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAP9014019.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(28266..28796)
                     /locus_tag="IV356_000292"
     CDS             complement(28266..28796)
                     /locus_tag="IV356_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HAP9014020.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(28800..29660)
                     /gene="rlmB"
                     /locus_tag="IV356_000293"
     CDS             complement(28800..29660)
                     /gene="rlmB"
                     /locus_tag="IV356_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HAP9014021.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(29653..30048)
                     /locus_tag="IV356_000294"
     CDS             complement(29653..30048)
                     /locus_tag="IV356_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAP9014022.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(30045..31457)
                     /locus_tag="IV356_000295"
     CDS             complement(30045..31457)
                     /locus_tag="IV356_000295"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HAP9014023.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(31454..31990)
                     /gene="cysE"
                     /locus_tag="IV356_000296"
     CDS             complement(31454..31990)
                     /gene="cysE"
                     /locus_tag="IV356_000296"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HAP9014024.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     gene            complement(32312..33772)
                     /locus_tag="IV356_000297"
     CDS             complement(32312..33772)
                     /locus_tag="IV356_000297"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HAP9014025.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(33942..35099)
                     /locus_tag="IV356_000298"
     CDS             complement(33942..35099)
                     /locus_tag="IV356_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HAP9014026.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(35133..36503)
                     /gene="radA"
                     /locus_tag="IV356_000299"
     CDS             complement(35133..36503)
                     /gene="radA"
                     /locus_tag="IV356_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HAP9014027.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(36566..37093)
                     /locus_tag="IV356_000300"
     CDS             complement(36566..37093)
                     /locus_tag="IV356_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HAP9014028.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            37323..38129
                     /gene="proB"
                     /locus_tag="IV356_000301"
     CDS             37323..38129
                     /gene="proB"
                     /locus_tag="IV356_000301"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HAP9014029.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            38126..39373
                     /locus_tag="IV356_000302"
     CDS             38126..39373
                     /locus_tag="IV356_000302"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HAP9014030.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            39449..39793
                     /locus_tag="IV356_000303"
     CDS             39449..39793
                     /locus_tag="IV356_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014031.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(39910..40236)
                     /locus_tag="IV356_000304"
     CDS             complement(39910..40236)
                     /locus_tag="IV356_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014032.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(40609..41810)
                     /locus_tag="IV356_000305"
                     /pseudo
     CDS             complement(40609..41810)
                     /locus_tag="IV356_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            41927..42442
                     /locus_tag="IV356_000306"
     CDS             41927..42442
                     /locus_tag="IV356_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP9014033.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(42641..43087)
                     /locus_tag="IV356_000307"
     CDS             complement(42641..43087)
                     /locus_tag="IV356_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAP9014034.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(43134..44612)
                     /gene="msr"
                     /locus_tag="IV356_000308"
     CDS             complement(43134..44612)
                     /gene="msr"
                     /locus_tag="IV356_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAP9014035.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(44966..45595)
                     /locus_tag="IV356_000309"
     CDS             complement(44966..45595)
                     /locus_tag="IV356_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAP9014036.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(45579..46043)
                     /locus_tag="IV356_000310"
     CDS             complement(45579..46043)
                     /locus_tag="IV356_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP9014037.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(46530..47798)
                     /locus_tag="IV356_000311"
     CDS             complement(46530..47798)
                     /locus_tag="IV356_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase"
                     /protein_id="HAP9014038.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(48029..48766)
                     /locus_tag="IV356_000312"
     CDS             complement(48029..48766)
                     /locus_tag="IV356_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP9014039.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(48833..49402)
                     /locus_tag="IV356_000313"
     CDS             complement(48833..49402)
                     /locus_tag="IV356_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HAP9014040.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            49530..50402
                     /locus_tag="IV356_000314"
     CDS             49530..50402
                     /locus_tag="IV356_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP9014041.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            50744..51616
                     /locus_tag="IV356_000315"
     CDS             50744..51616
                     /locus_tag="IV356_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP9014042.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            51613..53571
                     /locus_tag="IV356_000316"
     CDS             51613..53571
                     /locus_tag="IV356_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP9014043.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(53822..54673)
                     /locus_tag="IV356_000317"
     CDS             complement(53822..54673)
                     /locus_tag="IV356_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP9014044.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            54796..55263
                     /locus_tag="IV356_000318"
     CDS             54796..55263
                     /locus_tag="IV356_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HAP9014045.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(55526..56008)
                     /locus_tag="IV356_000319"
     CDS             complement(55526..56008)
                     /locus_tag="IV356_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP9014046.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(56108..56971)
                     /locus_tag="IV356_000320"
     CDS             complement(56108..56971)
                     /locus_tag="IV356_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP9014047.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            57569..58417
                     /locus_tag="IV356_000321"
     CDS             57569..58417
                     /locus_tag="IV356_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014048.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            complement(58588..58929)
                     /locus_tag="IV356_000322"
     CDS             complement(58588..58929)
                     /locus_tag="IV356_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HAP9014049.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SMEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAAEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            59015..59722
                     /locus_tag="IV356_000323"
     CDS             59015..59722
                     /locus_tag="IV356_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HAP9014050.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            59709..60032
                     /locus_tag="IV356_000324"
     CDS             59709..60032
                     /locus_tag="IV356_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAP9014051.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(60121..61158)
                     /locus_tag="IV356_000325"
     CDS             complement(60121..61158)
                     /locus_tag="IV356_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HAP9014052.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(61605..62588)
                     /locus_tag="IV356_000326"
     CDS             complement(61605..62588)
                     /locus_tag="IV356_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HAP9014053.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            complement(63004..63774)
                     /locus_tag="IV356_000327"
     CDS             complement(63004..63774)
                     /locus_tag="IV356_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9014054.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(63767..64702)
                     /locus_tag="IV356_000328"
     CDS             complement(63767..64702)
                     /locus_tag="IV356_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9014055.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(65296..66945)
                     /locus_tag="IV356_000329"
     CDS             complement(65296..66945)
                     /locus_tag="IV356_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAP9014056.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            complement(67140..68036)
                     /locus_tag="IV356_000330"
     CDS             complement(67140..68036)
                     /locus_tag="IV356_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP9014057.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(68029..68709)
                     /locus_tag="IV356_000331"
     CDS             complement(68029..68709)
                     /locus_tag="IV356_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP9014058.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(68710..69492)
                     /locus_tag="IV356_000332"
     CDS             complement(68710..69492)
                     /locus_tag="IV356_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP9014059.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(69485..70402)
                     /locus_tag="IV356_000333"
     CDS             complement(69485..70402)
                     /locus_tag="IV356_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP9014060.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(70405..70689)
                     /locus_tag="IV356_000334"
     CDS             complement(70405..70689)
                     /locus_tag="IV356_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP9014061.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            complement(71390..72010)
                     /locus_tag="IV356_000335"
     CDS             complement(71390..72010)
                     /locus_tag="IV356_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014062.1"
                     /translation="MNINRVIKLIGAKNINKVRSEFIFPEDFFNWFFYQFSECKRLLG
                     ENYYLKGIGGFMGNVADEQNIIKGISEQTSELTVTKAFISNGESLKNVTARIRKENEV
                     DIVFGIDHECNSVIYVTQSANLILFENGCKDDFMVVYLYDILIPKLRSLYMSSESIFV
                     SEQKGSFSKKIGIEVIESIMCHNHITLEELEILIGQKNNNTKIQVS"
     gene            complement(72091..>72434)
                     /locus_tag="IV356_000336"
     CDS             complement(72091..>72434)
                     /locus_tag="IV356_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014063.1"
                     /translation="NIKTSTKLICKLFKLDKISNIDDVKSKILTRKVSEPVKLTAQDK
                     KNGIVLYGDDAKYNYNWDTSSEAEVLSIPTTDTSGEKVTFKINFITAISKLEYGKQKK
                     RDNNDQYLPKK"
BASE COUNT        20829 a        15441 c        12751 g        23413 t
ORIGIN      
        1 taataccgag aaaatggttt ttgaacatca cttattcaaa ataaaaaaag attgtgacac
       61 gaattttgtc acaaccttta aatgtattcc tagagcaaag aagctaagcg aagaaatcca
      121 attctgatta tttattgtat ttctttgttc agcatccttg ctaaaagccc atattggaca
      181 aagtattcac tacacccatg atctcatctt ttcgagaacg tgctttttct gtcggatctt
      241 ctacctcttc tgtgtcaatt cgaacaataa atttccgatt catcgtcacg taagcaccgt
      301 cgttgatcaa aataaacagt tcgttctcat tatagtctgc acaggcatct ttccatacgt
      361 caaagccgtt tttttcagaa gggatatccc gtttaaccac agtttttcca cttaattcgt
      421 ggaacgttac gtcataatat ttcattatct ctacctcttt cgtcattcaa tattttgtac
      481 ttgttctctg attttttcta agatcgtctt agactggacg acttgatttt taatttcgat
      541 tgcatttgat ttggaaccga tcgtgttgat ttcccgattc atttcttgga tcaggaaatc
      601 taattcccga cctacaggac attgtgcttc gataagttca tctagttttt gtacatggat
      661 cgccagacga tccagttcct cgtgaatatc tccgcgttcc aacaagatgg ctagctccgt
      721 caacaaccgt tgctcatcga ctttcgctcc aagaaattcc tccagctttt tttgatacct
      781 tatttgaaat tccttttcat agatttctac aaaactatcg agttttttta gtacttcttt
      841 gaattcttca gtattctttt tcaacactaa agctaaagct tgaccttctt tttctcgact
      901 cgcctcaata gaatcaagtg cgcttttcaa tgtatctaga gctaactgtg ccaattcttc
      961 catgctctct tccggttttt cttctaccgt tacgaagttt tcgtccagcg cgaagcgttc
     1021 cgccatccga ctaattgaca cttgattttg actaccgtat cgttgttgaa ttccgtctgt
     1081 caattgagtg ataagtgaat caatcaattc ccagttgatg acgatctgtt tttcgttttt
     1141 gccaatataa gctagattca caaatacttc gattcgaccg cggcttaact gctgtttaat
     1201 aagctgacga aaatcgtttt caacaaagtt caggatttta ggacttcgta tttgaacatc
     1261 tagaaaacgc tggttgacac tttttatttc aatatctaac tgatacgctt ttgtttcgcg
     1321 gatggctttg ccaaaaccag tcatactttt cattcgacag ggtccttcct cattacatat
     1381 tttctattgc tttttgcagt tgttcaaact cttcgttcgt caatgtcagg cctttcccca
     1441 ttttttcatg gtctggcgcc caatctcgaa gatcgaattt tggcgggcga ccattccagc
     1501 tgactaggtt cagttcttta cgccacccct tgttgttttc tgacaatata gcgatttctt
     1561 ctacgatttc atatgaaaat tcttgtgcca tggttgttcc tccttgagat aatataaata
     1621 taggatcagt aatgtgtcaa ctggttgctt aagcaattca tgctgcaaac gatccttgcg
     1681 ttttccttgt agcagataat caaaataaac agttttcgtg cgctcatttt gtattttttg
     1741 ctggtatttt cgataccttc gccattcttc agtacttaat tgaccaattt gtgccaataa
     1801 atcatccggc atacttttta tatcttgttg gcagatcatt tgaatcatca tgtctacttg
     1861 atagatttca ttgggcagta aaaaatgttt ttttgctaaa agttctagca tcgccaatcc
     1921 gcatgtctct ggtacgaccc tgttcttata taaattacgc agtttttgcc aaaattttat
     1981 gcttttgaaa aaagataatt ctaactgaat ttcttttgtt aagtaagaca aaaatcctcg
     2041 ccagtatgtt cttgcaggtt taacagaatg aaatgtatac cagttcccat agtaatagcc
     2101 taatcgtttt ttcatttcca gatagcctaa ttgtaaattt aattggttcc tttggctatc
     2161 aaaaagcaga aagctgccta gtgtccacaa tgtttgacat ttccaatgga taaaaatgtc
     2221 tggcatacga atttttttcg ctgggcctgg cccttgcaca tctacgacaa atgcctctgt
     2281 tgctcctttg ttaatcgcaa tatcaatagg tattttgttg cgatacccac cgtctgcata
     2341 tttatttttt ccgatctttc gataagccat agcgggataa aatgaagcag aggcgagtat
     2401 ccaatctggt atttcttctg tttttgtctg ttggatatca gtcactactt ccgctagttc
     2461 tggcagttta gtagacaccg tatataaacg tattttggga ttatgtttga gtaaggacaa
     2521 atccaaattg tctttgacca tcttttccaa tggagcagaa gaaaccccgc cttcaattag
     2581 tgctgttttc gtcatttggc gtctttctcg atagaagcgt tcacgaaggt cttcaactgc
     2641 agccatttct ggtaacgcaa gcacttgtct tgtcgacagc tttttccata aattcacagc
     2701 ttttttcata tctccttgta aaatcaatgc gccgttcaac gcacctaccg aggtacctgt
     2761 gataatctca aagttgatat catgttcctt cagcgcctgc cacacaccaa tctgataagc
     2821 accgtgcgct cctcctccac ctaaaacaag tgctgtatga tagaccagct ttttatttaa
     2881 ttgtgtggtt ccttgatagc cgtttttatg aaaaatacgc aaccattctt ctgatagagg
     2941 agattgaaat aaaaaacaac agttttcttt aataaaaaaa cgagcgcaag cttccatata
     3001 ccgaaaaaat tttttccatt caaaagtttc accttcaatc aacagattat taaaaataac
     3061 atctcctcta cttttagcaa tagtaaaata gacggtatat tttttcgata ctgctttaaa
     3121 agcacattgc ttttttgcag aacgccaaaa agcgtctcta ctttcttgat gactttgaaa
     3181 aaatggaagg ggttgttttg cttgctggat aggcgaatac agcgacattt tctgtgaaaa
     3241 gtaaactttt tttatctcca tcgcgctctc ctttttcttc aagtatacca gtacgtcata
     3301 aaaaggtcat gagtctcgta ttcgactttg tagattccat aagaaaacaa ttcataaaac
     3361 ctcctttaaa taaaaaaata caaaaatcac aaaaattaat tgaaaatgag agtgttttca
     3421 atgaaaacgt gattttgtaa tggaatttta aaataaaaga aacaagcttt tttaatgcaa
     3481 atgttgtaaa ataaaagaga ttaagaggaa ataagaggag gaacatgatg actgagtcag
     3541 tttatgtaca tattgatacc acaagtaatg ctgttttaac aaaagggctg actgctactg
     3601 actttgcaaa cagtatcgtg cattttcctc aaaacttgct cttgcttgat ccatctgctt
     3661 ctgctggaga atatgaatcc catacagggc tgaaagtaat ccgtggtaca gaaaatattc
     3721 agcgtttctt ttcctcttct cgtaacaggc gtggattcga tgaattgaag tggatcgact
     3781 ttactgattt aacgatgctg aaagaattga cacctttaga aatttcagaa ttattatatt
     3841 ttggtcatat gaaaacacat cttcattcgc cgttttttta taaactacag aataattttg
     3901 tatacttcga tcttaatgat cagctgaatc ggatttatta tcgctattta gatgaatttt
     3961 ataggatttt tgctagtaaa ttaagttcga tcttgtcaga taagatcaat gtaaaaaaat
     4021 cttttttcaa aaaagaaaca cctgttgaaa aaatcagtgt ggaattattg aaagaaatgc
     4081 gtaatttgat gcaggaaggg atcatttttt cttttgatca agttggtttg atcgatggta
     4141 aatatcgtat cccaatctat gtgattgaag attatatttg gaaattaaaa ggcacccggt
     4201 atcgagaaga ggaaatcatc gctactttaa tctactctgt caccgatcga cactggcaat
     4261 tggtagaaga tgccgatctt tcttatctgc cattgaagta gatctatttc ttatcaaaaa
     4321 ataaaaagga aacaagaaac taggacatga ttctgtctca agtttcttgc ttctttttta
     4381 tttacagctc ctgtcgttta tctggcacaa aaatcgaagg agtcgtttgt tggatcccta
     4441 ataaaacgat gatcgttaca atagctgtac tcaacccgct ggcaccattc attacgaaag
     4501 aaaagagcca aggattcatc ccccatagtg catacgctcc ccagaaaacc actcctgcaa
     4561 taaaatgcca aaaatatctg gaaagtgcgc caatcaatgc accaaacacg atgctttttc
     4621 taatttgttt cgtattatcg tctacatagc ctttttggac atttgaagcc atgagccctg
     4681 ctgcgcctgc aaaagtatag gcaatcgggt actcaatcaa cacttgaacg acacttaaat
     4741 aataaacttg tcccaacgga aaatgtagga tgccccaaat gaaacctgcc agcatccctg
     4801 cctttgtccc tcttcttaac gcaaaaagag tcaatggaat ctgccctaat gaaatagaaa
     4861 aactgctgcc gatctggatc ggaatcaacg acaacaccat cgctaacgct gcaacaatcg
     4921 ttccttctac ccaaactcta ttttttccca taaaaaaact tcctcctttg aataaaaaag
     4981 tcacaaagga ggaagcagct ttcgaaaata gtcaaacagc tgtttattca caattcctac
     5041 gctcgcataa ccgatacagg tacgaagggt ttagaaatag attcaatctc agcccaattg
     5101 gactcccctt tgtgagttta tttattattt attttttgtt tcaaacaatg gactaactgg
     5161 tttgttttca tggatacgtt tgattgcatc tcccattagt ccgccaacac ttacttcatc
     5221 gattttgtcg attttacgat cttctggaag atagatcgag tctgtaacaa ctagacgctc
     5281 gatagctgaa tcttctattc tttgtaaagc agggccggat aatactggat gtgtacatga
     5341 agcatacaca ctagttgcac cagcttcttt caaagcattg gcagccaatg tgatcgtacc
     5401 tgctgtatcg atcatatcat cgatcagtac acaagttttg cctttgactt gtccaatgat
     5461 attcattact tctgcaacat ttgcttttgg acggcgtttg tctatgatcg caatcggaga
     5521 tttcaaaaat tccgctaatt tacgtgcccg tgtgacacca ccatggtctg gtgaaacaac
     5581 gacaacatca tcgcctttga ttcctttttc taagaaataa ttggcaataa gtggcgcacc
     5641 catcaaatga tcgactggaa tatcaaagaa accttggatt tgaactgcat gaaggtccaa
     5701 agtcagcatt cttgttgcac cagctttttg aatcatgttt gctactaatt tcgctgtgat
     5761 tggttcccgt gcacgtgctt tacggtcttg acgcgcatag ccataataag gcatgactac
     5821 gttgattgtt tttgcacttg ctcgtttcag tgcgtcaatc atgatcagca actccatcaa
     5881 gttatcattg actgggctgc tcgttgattg aataacatag acatgcgatc cacgaatact
     5941 ttcttcaatg tttacttgaa tttctccatc actaaattga gtaacagatg attttcctaa
     6001 ctcgacgccg actgctgctg caattttctc tgctaatggg cgattggaat ttaacgcaaa
     6061 aatttttaat cttgggtcaa agtaatgttt tgacatgggg acctccactt tctttttcac
     6121 aactctagaa ttctacctaa taaatagtag tcatattttt taaataaatc aagtgatttt
     6181 gcaaaagtct tagtttagat aagggagttt ttttgcatat ccttctttat tgacttgtct
     6241 tgctctcgca attgccagcg catattctgg aatattgtct gtaattgttg acccggcagc
     6301 aatcgaactg tttttagcta cctcgacagg tccgatgata ttcgtgctag aaccaataaa
     6361 gctgtggtcg ccgacagtcg tatgatgttt gttctttcca tcatagttga cgaagacaac
     6421 accacatccg acattgattt cttctcccag cgtagcatca ccaacataag tcaagtgacc
     6481 gactttagtt cctttgccga tttgagcatt tttcacttcc acaaagtttc cgatatggac
     6541 gttttcgcca atttcagctt ttggtcgtaa atgtgcataa ggtcccacat ctgcatgttt
     6601 cttgacatgg ctgctttcaa tgactgagtt ttcaatgacg acgtgatcct caatcctact
     6661 gtctacgatt tttgaatgtg acccgatgac acaatcagaa ccaatgactg tatttccttg
     6721 gatttgtaca cctgcttcga tcaatgtgtc tggaccgatt tctacgcctg catcgatgta
     6781 tgtcgttgct gaatcgacaa agcttacgcc attgaccata tgcatctggt taattcgctt
     6841 tctcatgatc tcatttgctt tagctaacgc gatccgatca ttgactccca ttgattcttc
     6901 aaaatcatcc gtttgataag cagcaactgt atggccttct tcttttaaga tttcgatgat
     6961 atctgttaga tagtattcac cttgagcatt gtttgttcca actttgctta acgcatcgaa
     7021 caaagcttcg ttgtcaaaac agtaagttcc tgtattgatt tcttgtacaa gagcttcttc
     7081 tggtgttgca tctttttgtt ccacgatttt ttctacgatc ccaatatggt cacggatgat
     7141 tcgtccatat cctgttgggt tttctgcttg tgccgtcaag atcgttgcac ttgcattttt
     7201 tccttggtga tattcaaaaa gattgttcag cgtttcagta gtcaataatg gtgtatcgcc
     7261 actgataact aacgttgttc ctttttttcc ttccaagaaa gaagcagctt gcaaaacagc
     7321 atgtcctgtt cccaattgtt ctgcttgtaa cgcatattta ctgcgttctc ctagttgtgc
     7381 tttaacttgt tctgctccgt gtccaacgat cgtaatcact tcatctggtt tcgtttcact
     7441 gacccgatta atgatatgtt ctaccatagg tttaccagaa acgggatgta aaactttata
     7501 taattttgac ttcatgcggg tacctttccc tgccgccaaa ataattgcat aacgtgcgtc
     7561 caactgcgtc actcctaaat atagtttgct gatttcagtt tatcccagta tacccatttt
     7621 ttcaacaaaa caagtgattt tcttttatcc cagcgttttc tggataaaaa aatagataga
     7681 ccataacggg cctatctatt tggtaaccgg tgctctcctg ccaactcctc ggtcacaagt
     7741 cacactactc ataaaacatg aaaagctgtt ttttgaaatc gtttcttgtg acttagagtt
     7801 aaacggtagg cttacaacct cttcattaaa cgtttttcaa tcagctgacc ttcggtatta
     7861 gctcaataaa cggcaaaata tgaggagcaa tttttccgtt tattgagcta atactcagga
     7921 caggacgctg atttcacaac ctctagataa acggtgttca aaagccagtt tctcggtatt
     7981 aagccaaatt tatgaaaaaa tgtggaaagc cattttcaca aaatttttct tactactcga
     8041 aactaagcag ctttttcaca acctcttatt ctgaaaaata atttcctggc acaaccgtaa
     8101 tatttttcgt ttgagtatct acatctttga cataaagcag tgacgtataa tcatcgatgg
     8161 cgcgatgacc gttgaatttt gattcggcaa atacagtgat gccaacaagt tctgattcga
     8221 attcttcaat caagctcttc attccgttga ctgttccgcc gcctttcatg aaatcatcca
     8281 ctacaaggac acgtgaacca cgtttcaaac ttctcttaga cagttccatc ttttcaattc
     8341 tttcagaaga tccagacaca tagttgacac ttactgttga tccttctgtt atttttgagt
     8401 cccggcgtac aataacgaat ggcgcattca gataatagga cacagcttgg gcaataggta
     8461 cgccttttgt ggctacagtc attacagcat cgattttttc accaaggtat ttagaagcaa
     8521 tgattcttcc aacttgacgc agcagttcag gttctcctaa caaatcagag agataaacat
     8581 atcctcctgg aagcagacgg tcttgttctg atagacgttc tgctagagat tcaatatatt
     8641 ttttcgcctc ttcatatgaa atttcaggga tgaacaatac accacctgca gcacccggga
     8701 ttgtttccaa ggttccatac cctcgttctt taaatgtttt cttgatgatt cccaaatctt
     8761 cactgataga agatttagca gattcataac gttcggcaaa gcttgttaag gaaatcaatt
     8821 catgcgggtg attcaataaa tactgtgtca tgtcaactag acgttcactg cgacgtactt
     8881 tcacctattc caactccttt taagaaattt tatcgtttta cattatataa gtttttcttc
     8941 aaaaattcga gcattttatg aaaaaataag aaaatagttc ggtatttatt aaaataaaaa
     9001 gaagcctata aaaaattttt cgtttttata aggcttcttt tctttataat ttagttattt
     9061 tttcttctga aggcaaccaa tattcgtttg atgatattta caatcaggaa caaagcaata
     9121 aagactaatg tgattgttgc tcctggaggt gtatctagat aaaacgagct agttagtcct
     9181 gacagcatcc ctagaaatcc tacacaaaca ctgatagcaa tcacgacatt gaagcttttg
     9241 cctaatcgca taccgattgc tgcgggaaga accatgattg cggatatcaa aagtgcaccg
     9301 gcaatcggga tcatcacagc aatagccaca ccagtaatca cattgaacat catcgacatc
     9361 aaatgaacgg gtagcccatc cacgtgggcg gtatcttcat caaaagtcag aacatacatc
     9421 ggccgtttga ataaaaagaa caatataccg atggcaacga ataagattcc taaaaagatg
     9481 acttgctccc atgtaatggt cacgatcgaa ccaaacagat aggattggat acttgttgct
     9541 gaattccctc cgctcaaatt catcaatact aacgctagcg ccaaaccacc agccattaaa
     9601 atggcaatgg agatttctga ataggttcgg tagatcgttc gcagatactc caatatcaca
     9661 gctgctaata caacgactag catggtcgta agtgtaggat taaggttcaa aaagaatcct
     9721 aacgctaccc ctgctaaaga gacatgagaa agcgtatcag ccatcagcga ttgtcttctg
     9781 atcactaaaa acacacctag catcggggcg attccggcaa tgaagatagc ggcaagaaac
     9841 gctcttctca tgaattcata tgaaagcaac gccattgaga atcctccttt ctcaccagtc
     9901 ggatctgtct gtccgcatac tgtttgatat cttcatgatc atgggtgatc attagaactg
     9961 atttcccatg gacatgcgca ctatgtcgga gaagacgata aaattcattt ctggattctt
    10021 catccatacc tgttgttggt tcatcaagaa caaataagtc agggtcagta gcaaaaatac
    10081 gcgctaaact gattcgctgc ttttgtccgc cagacaattc acctattcgc cgatttcgca
    10141 tatcccacat ccctacagct tctaaagcac gctgtacatg ttgatgatct ttttcagaga
    10201 gacgcttgaa ccagcggcct cttggatatc ttcctgaacg gactaattcg atcaccgtac
    10261 taggaaaacc tgcattgaaa gatgcaactt gttgaggaat ataaccgata cttaattttt
    10321 ttccttcttg atttttctca gcaatcttta tcattccttt tgaaggtttc agtaatccta
    10381 acgatgcttt caccaaggtt gacttggctg ctccattttc tccagttaaa atgacaaatt
    10441 cacccgcatc tacatgataa gagacatctt ctagtacagg ttcatcatca tagtaaaagg
    10501 tcaaatcaga tatttcgata taacgcacct tacaacctcc attctaaaac ttaattgata
    10561 ctttctttta aagctttcag atttttttcc atgacagaaa tataattttc gcctgctttg
    10621 atttgttcat tagtcaagct ttctaaagga ttcaacactt ctagcttcac tcctgtttca
    10681 ttcgacaatg tctcagctac cttcgaagag gcattttctt caaaataaat cactttgatg
    10741 ttgtttttct tcacaaattc ttttagctca gctaagcgac ttggtgtggg ttcctgatct
    10801 ggtgaaacgc ccgaaatcgc tacttgtttt aagtcgtatt gattcgctaa ataagcaaaa
    10861 gcagcatgct gagtgacaaa tgtgcggttt gttgcatctt ttagctcatc ggagtatttt
    10921 tgatccagtg cttcaagctt tttgatataa gcatcggcat tcttcgtaaa agtttccttt
    10981 ttatctggat atttttcgcc taattcttca gcaatcgttc tgacttcttt tatagctaat
    11041 accggatcga gccaaacatg tggatcgtat tcatgtgaat gaccatgccc ttcttctgat
    11101 tcttcatgtt cgtctgcttc ttgcgattct aaacggtcga ttcctttagc tgcttcgatc
    11161 atcaaggtct gtttgctatc cactgaatcc tttaacgaat ccacaaaaaa ttccatgtct
    11221 gaactattat acacgaaaac atctgcatcg gaaatttctg ctctttcttt tgcacttggt
    11281 tcgaaatcat gcggctccgt tccagcaggg atcaaaagtt tcacgtttcc ttcatcccct
    11341 acgatctctt ttgtaaaatc atacatcgga taaaaagtcg taacgatcgt caaatcctct
    11401 tttttgtctg cttccttgtt cgtatttcca catgctgcaa acagtaaagc acctatcatt
    11461 accgtagctg tcaaaagata ttttttcatt tatatgctcc tttcaatgaa caaatcggaa
    11521 ttttacgatt tattaacgtg aactaatgta tcaaaataaa aaaacacagt caatagaaat
    11581 ccatcaattt ctgatttaag catgtatatt cttgattaaa tcgtaaaatg gatgagttgc
    11641 tgctcatatc tagccatttc actacaataa aaaactgaag aataccattt taggattcct
    11701 cagtttttca tcacctattt tacttcttat attttattgc agggttcgta ctaaataaac
    11761 ttcctcacaa aaacctttta acccattata tactctctgc gctcttgaat aatgttgaca
    11821 caaggcaaaa acggttggtc cgcttccact catcaatgca gcatctgctc cgtacttgat
    11881 catacgctct ttgatttgat ggatgactgg atgccgcttt cccgttatat cttctaaact
    11941 gtttcccatt tttttgatca tctgctgata atcttgctct cggatggctt cagcaagtcc
    12001 gtggatgtct tgatgttgga tggcttgcgt atctacttct ctaaacactg tacgtgtaga
    12061 gacactcatt cttggtttga ccaacacaac ccagcactgt ggcatagaag gtaatacttg
    12121 gatttcttcc cctttgccac cgacaaatgc cgtacttccg tagacacagt aaggaacatc
    12181 tgtaccgact tccaaaccga tttctgccag ttcttctaac gaacagccca gattccataa
    12241 ttggttgatc cctcttagag cagctgcaca gtctgtactt cctccgccta atccagctgc
    12301 tactggaata ttcttcttaa caaagatctt gacaccggtt ttgatattgt atttattttt
    12361 tagcaataaa gcagcttgat aaacattgtt ccgttcatct accggtaaaa atgctttatt
    12421 tgtttctaca atgattttgt cttctgttat ttcttcaaaa aatagatgat ctgccaagtc
    12481 tacgctcgac atcaccattt ccaactcatg atacccatct tgccgtctat ataatacatc
    12541 cagtcctaaa tttatcttgg ctggcgcttt ttcaatcaat tccatcctct cacccattcg
    12601 aaaagtctaa gtcgcaagta ttctatcata gggaaaaata aaagtatagc ttatgtctgc
    12661 ctagtggttg attttgtcat cgtttcaaca gctttcacag aattttctct tcataatcca
    12721 aacaagttct agtgattctt ataattctgt gagcacttct tctgccaaac tcggaacatt
    12781 tcctttttct tttcctatca gactgagtag ctgcatggta gcaaatccga aattacttcc
    12841 tttcctataa gcaaaataac gtccttccca atgatcgaca tattttaatt tcttttcata
    12901 agcagactgg aaggaataga aaaaattacc ataattatat acgatatgca tgactttttc
    12961 ttgaaagaaa gaaaaatctg tttctccaac attagctaat ggagctaagc ctagattggc
    13021 ttccgagtag cccattttct cgtatacaat aaacagattg gctaacagat agtcagctaa
    13081 ttcctcagat tctttaggta agacccgcaa caaatcatat cccgcctgct tcttcgtcat
    13141 cggctgagcg gtgatgaagc caacgacttt ttgatcttta cggacaatac cgacaccgct
    13201 agataataca tatgatttat caaatcgtcc cacagagaag tatttttctc gtgcaccttg
    13261 aagccatttt tgtgaaactt catttacagc ttgatgtaat tcttccggca gttgatcgta
    13321 ccaagtaaaa tggtatcctt ctttcatcaa acgttgatat tcaagttgct gactcagccg
    13381 agacaagtct tctgttgcta gatcaacaat ccctgcttca cctactttcg tgaagtgaaa
    13441 acccaattca tgaagcatca ctacgtagct ttctgatatc ttataaaacg caagctgata
    13501 gcctaaacaa tctgcttgtt tcataaactg attcgttgct gcccgcatca ttttaggatt
    13561 gccaactgga tctcctaaaa caaagcattt gtttcctttg atctgataac caaaaacgac
    13621 ttgatcttgg tcgtcttctt ggtaataaaa ataactgtaa cctgacaagc gaagctgatg
    13681 gcttgtagct gtgcctccgt atgtttccaa taaacggtca aaacggtctt tttcgtactc
    13741 actgccaagc ttcgtagtat cttcagctaa atattgataa agcgccacta aagctagcaa
    13801 tgagatgccc aaaccaataa gccctgagaa ccacacatca tctgaaggaa acaaaataaa
    13861 atgatttcct gttattcgac cgactaaaaa gcgtccgctg tgatagcctg caattgcgta
    13921 aacgataaac aaaaagccga acaagctagc atcaaagatt atagctcccc aagaataaac
    13981 gaattttgtt cgataaaatt cttttctgga taaccacaca gctaacagaa tcaagacata
    14041 taccaatatc aactgccaag ataacgtacg tgtgattgta tttaaaatac caaaagatag
    14101 taaagcaatc gtaggcagaa atgccttttt gacttttact gaaagtgctc tagcaaggcc
    14161 gagtaataaa aagccaacca atagattcac tgtctgatct aaaaaattga atgagaacgg
    14221 caataatact tgaaatagcc gactgattgc agacagatta gtgattgttg atagaagtac
    14281 catcatgatc cccgcaaaat agacagcact tacgagcacg atatgcgcaa ccttttggaa
    14341 aaacagtcgc ggaatgttat ctaaaaatcg attgattttg actcctgtat gtgtgatgaa
    14401 caatagaagt cccgtcataa aaggtagaac ataataaaac aaccgataat ataatagcca
    14461 aactactgct acatcttgcc gaacaggcaa ttgactcatt cctaagatca tcaaaacgtc
    14521 aaaagtcccc attccacctg ggaccatcgt cagcattcct atcaatgtag caatcatgaa
    14581 cataggatag atcgaaagca tcgaaatatc tattctcatc aacttgccga tgatcaaaaa
    14641 taccgcaagg gctcccgtcc attgtccaaa ggatgccagt agcagaccaa gcaagccttt
    14701 tggataaaac tcgaagaaca atgtctttct ctttagataa gcaaaaaaga aaatgactgg
    14761 tgctaaaaaa ctaccgccga aaagccagat ccaatagctt cgaaaaatac tttctgactg
    14821 aataaaaaag acatcaataa atgtaagaaa cgaccataca gacaaaccag tcagcataaa
    14881 tagtgcgact tttgatacag tggctaaaac catttttcta tttgtctgct ttccataaaa
    14941 actagcccgc agacttgctc ctaccacacc accaaaaccg gcgagattgt tgatcgtgtt
    15001 tgttacccac gcagcaagaa gaaactcttt tctttccatt tttggttttc cttgtttttc
    15061 taagactctg atcgtcaccc aatcatacaa caacatcgga gtgacaccca gcagtccagc
    15121 cagaatcatg agcaggatcg tcatgcggct ttgttgtccc atcctttgcc aaatatcttg
    15181 ccaactcatg ccattagcaa tatttgcgac ttgatttgcc acaaagacta acacggagcc
    15241 gaaaaaaatc agttttaaaa tcagactatg ttcctttatc cattgcagca tcaagtatcg
    15301 tttatttttc acattttccc attcttaact tgtatacttt tgtgtcatac cccaatgtta
    15361 tcttatttat tttaattttt ccactttaga cctgttcttt gcttgcgatg atagaaaaag
    15421 aaagatatcc taatgctaaa ggagaggata acatgaaagt aggatttatc ggcacaggga
    15481 atatggcaca agctattatt gatggtttat taaaaaaagg aacagtctcg aaagaagagg
    15541 tgttcgtttc cagtggacat tttgaaaatg cacaaaaatt tgctgctgaa actggcgtcc
    15601 atgcatgcaa aagtaatcag gaagttgcat cacaatcaga tatcgttctt ttagccgtga
    15661 aaccaaaaat cattgaaaaa gtattggaag aactaagaga atatagccag aaagtcttat
    15721 tcatttctat tgcttcagga aaatcattaa cagatttaga aacagcgctt gaagatcctc
    15781 aggcctccat cgtacgtgtg atgccgaatg tcaatgtcag cgtaggagca ggcgtttctg
    15841 cgatttgcaa aaatgaagct gccacggagg aacagcttca gcaagctacg atgatttttg
    15901 aagcaatcgg cagcgtctat cctttagcag aatcagattt cagtacattc attggccttg
    15961 ctggcagctc acccgcattc gtttacatgc tgatcgatgc gatgggacgg actggtgtac
    16021 tgaatggttt gtccaaacag acagccactg agattgctgc aaaagcaatt atgggttctt
    16081 gtcaaaaatt cctttcaagt gataaaaatc catgggaact tgtagaccaa gtttcttctc
    16141 ctggcggtac aactgttgca ggtgtagttg ccttagaaga agcaggattc atcccagcaa
    16201 tcatcaaagg aatcaatacg acgatcgaga aagatcttga gatgttgaat aaaaaataat
    16261 gatagcaatg ttttttcgtg ccttacaaaa aaagaagagc tgtggctttt gccgcggctc
    16321 ttcttttgta ttttttatta tttagcataa tcagttgcac gagtttcccg aataacgatt
    16381 actttgatgt gtccaggata atccagttct tcttcgattc gtttacgaat atcacgtact
    16441 aaacgaacag cgtctaaatc cgagatttct tctggcttga ccattacccg aacttcgcgt
    16501 ccagcttgaa ctgcgtaact tgattctaca ccggcgaagc tgttcgaaat attttccaga
    16561 cttcttaaac gacggatgta gttttctaat gattcacttc gcgcaccagg tcttgctgct
    16621 gagagcgcat ctgctgcagc tacaaggaca gagataacag aagtagcttc cacatctcca
    16681 tgatgagaag cgatcgcgtt gattactact gggttttctt tgtacttggc agctaattcc
    16741 gcaccgatct caacgtgaga tccttcaatc tcatggtcaa gtgctttccc aatatcatgg
    16801 agcaacccgg cacgttttgc taattggata tcttcgccaa gctctgctgc taagatacca
    16861 gctaattttg caacctcgac cgaatgcttc aagacgtttt gtccataact agttctgaat
    16921 cgcagacgtc cgatgatctt gattagatct ggatgaagtg tatgagcacc gacttcaaac
    16981 gctgcctctt ccccgtattc gcgaatacgt tcatccattt ctttacgaga tttctcgacc
    17041 atttcttcga tacgcgctgg atggattcgt ccatcttgta tcagtttttc caaggtcatc
    17101 cgtgcgattt ctcttcggat tggatcgaat ccggaaagaa caactgcttc cggtgtatca
    17161 tcgatgatta aatcgatacc agtcagcgtc tcaagcgttc gaatattacg accttctcgt
    17221 ccaatgatac gacctttcat ttcatcattc ggaagggtaa cgactgaaac agtcgtttct
    17281 gaaacttgat ctgctgcgca gcgttgaatc gctaatgata ataagttttt cgctttgcga
    17341 tctgcttctt ctttggcacg ctgttcagat tcttttacca ttagagttaa ctcatgattc
    17401 agctcttctt cagtcgattt catgatgaca tctcgtgcgt cctcttttga taaaccagca
    17461 attttttcta gttctttttg ttgatcttca atcatttttt caacgtcttt ttctcgctct
    17521 tcaattaatt gctgttttga actaagtgct tcttctttac tttcaagtga gttctcgcgt
    17581 ttttctaacg agtcatcttt acgattcagc gtttgttcgc gttgaatcaa acgattctct
    17641 tgagatttta attctaactt actttctctc agctcacttt caacttcaga acggtatttc
    17701 tgattttctt ccttagcttc taacaatgct tcttttttta gagtttctgc ttcttttttt
    17761 gcactatcga tgattccagc agctgatgat tgtgcaccag ctatttcttt ctcgtgacgt
    17821 gactttgcga ccataaaccc taaaccaaga ccgacaatta aaccgatgat agcgaggaga
    17881 atgttgaata ccataaaatc cacctccata ctatcttttt catttttatc atctatacag
    17941 cttctatgat aaattattct aaactcgtca atatgcatct tcgcatatat gtgtacaaaa
    18001 aacatgcaca actttattct aatgtttgta ccccgtagtg tcaactttaa ataaacaaag
    18061 aaacggcttt ctacttattc attaaacgat ggtttttaaa ataaatgaca ctagtttcat
    18121 ataggtaaac ctttaaattg agaaactttt ctattaaatt attctttgta gatgaacaga
    18181 tatttttatt ttatgtaccc actcgtataa ttaaataact cacgatttct ttattcaata
    18241 aaaaaacggc aggtcaagga gagtacctac tcttcagacc agccgttttt gtttatcata
    18301 atttttattc ttctactaaa ggcaattctt cttgtccttt ttcatcttct gggacagcga
    18361 cttcttcacc aataccataa gctgctctaa ctagagcaga aacttctgcc atcatttcag
    18421 gatgattagc catatagatt ttagcgtttt cccgtccttg accaatccga tcttctttat
    18481 aagaatacca agcaccgctt ttatcaacaa tgtctttttc tactgccatg tctagaagtt
    18541 ctccttcttg tgagatccct aaaccataca tgacatctac ttcagcgatt ttgaaaggag
    18601 gtgctacttt gttttttacg actttgatct ttgtacggtt accaacaata tctgtacctt
    18661 gtttcaattg ttctgcacga cgtacttcca aacggatcgt tgcgtagaat ttcaatgcgc
    18721 gtcctccagg agtgatttct ggattcccaa acatcacgcc tactttttca cggatttggt
    18781 tgatgaaaat agcgattgtt tttgttttgt tgatcgaacc agagagttta cgcaatgctt
    18841 gagacatcaa acgtgcttgt aacccgacat gtgagtcacc catttcgccg tcgatttctg
    18901 ctcgtggaac taaagcagca actgaatcga ctactacgat atctacagcc ccacttgata
    18961 ctaaagcatc agcgatctct agaccttgtt ctcctgtgtc aggctgtgaa agaagtagtt
    19021 catcgatatt cacacctaat ttttgtgcat attgcggatc taacgcatgc tcagcatcaa
    19081 tgaaagcggc cgttccgcca tttttttgta cttctgcaat agcgtgtagt gcaactgttg
    19141 ttttacctga actttcaggt ccatatactt cgatgatacg tccacggggg taaccgccga
    19201 cacctaaagc gacatctaac gcaagagagc cacttggaat tgtagagatt tgttggtcga
    19261 ttttttcgcc caatttcata atagagcctt taccatagct cttttcaatt tttttcagtg
    19321 cagcatctaa ggctgcttta cgatcatctg ccaatacgat aatcctcctt atatttacaa
    19381 atcagagcaa catttcatta tccttatcat atctttttta gtgaaaaaaa gcaagaaaaa
    19441 accgaacaaa tattcgcatt tatcattttc ttaaaagctg ttttctcaaa agatcaaatc
    19501 cttgcataac cgcattatat ctgatagcag cacgatctct ggcaaagtga tatttttccg
    19561 aaaccacgcc gtctttagat gaaatagcga tccatactgt tcctgcagat tgaccttcta
    19621 acgtgtccgg tccagccact ccggtgaaag ctacactgta atctgttctt gctatctcac
    19681 gtgcttgaat ggccatctgc tccacacatt ctttgctgac tgttccatat tctgctaata
    19741 gctccggatc aatctccaga aaaccagctt ttgtttggag cgagtaggta acgaatccgc
    19801 ctggaaatac ttcagataca ccagcaatgt cgcctaatgc ggcttggaag gcgccggctg
    19861 tcaaactttc cgctgctgtt acagtctgct tgttttcttt cagtagttcc actacgactt
    19921 ttgctagcga attatcatcg ccgtatccat aaaaatattc ccctactcgt tcttggattt
    19981 tttcttctaa tgctaaaaga gcttgattcc ctgcctgaac atcatttgtt ttcactgtca
    20041 gtcgtaatgt cacttcattt ggtttggcat atggtgcgat cgttggattg atctgtgtct
    20101 caatcagatc ttttagctca gtgaccagtc gcgattcacc aatcccataa aagcgcaaaa
    20161 ctttagaaat tagtttttct tcagaaggaa aacgttcctc tagtaaagga cgtacttgtt
    20221 ccacaaacat tggtttcaac tcattaggcg gaccgggaag aaggatatac gcatgtgtat
    20281 ctgtttgata aaaagtccct aaagcaagcc ctgtacgatt tggtagagga accccgcctt
    20341 cgataatctg ggactgttgc agattgtttt tggtcatttt tcgatgggtt gtttcaaaat
    20401 atgccaataa ttttttgtat ccttccgtat tttgtatgag agacttaccg aggtgagccg
    20461 cagttgcttc ttttgtcagg tcatcttctg tcggtcctaa tccgccacat aagagtatga
    20521 gttcacttct tgtttcagct agagcaatca actcttctaa acgctgctga ttatctccta
    20581 caactgtttg ataataaact tcgataccta gatcagctag ctgttctgac aagaaagtgg
    20641 cattcgtatt cacgacttgt cctagtaaaa gttctgttcc gacagctatt atttctgctt
    20701 tcattacttc ccgctccctt atatagtata cgctgtattt ttatattttt ttatttaaaa
    20761 agagggcaag gagctgtgac aaaaatcttg tcacagctcc ttgttccaaa taaacagtgt
    20821 tctcctgcca aaacctcggt cataagtcac aatatacata aaacatgaaa agctgttttt
    20881 tgaaattatc ccttgtgact cagagttaga cggcaggctc acaacctctc cactaaacga
    20941 tacttacatt gatcctttga acacaccgct gtttttgatg aagtaatcca cacctgaata
    21001 gatagtaaag atcagacaag cataaagcat gatttgatct actggaatac cgatcaggct
    21061 gaatgggata ttattgataa acagcaagat aatagcaacc atttgtgtag ccgtcttgac
    21121 ttttcccggc caagctgcag ccatgacttc tccatgttcg acaagtagta aacgcaagcc
    21181 tgtgacggct aattcacgac agacaatgat cgctactacc caaccagggg cctttccttg
    21241 gtcaaccaac atgataaaag cagtcataac tagcatttta tctgccaacg ggtccgcaaa
    21301 cttgccaaaa ttagtgacaa ggcctcgcgc acgggcaatt tttccatcta accagtctgt
    21361 gatactagct aaagcaaaaa taactgcacc tactagctgt gtgacagcca gtgtggtgtc
    21421 tcctacgtta aattgtcccc aatctaaagg taaacctaca accaaaatga aaatcgggat
    21481 catacaaatt ctaagtacag ttaatttatt tggtaaattc acactatcga ctcctttctt
    21541 ccctattcta cgtgactatc agcgaagttt ccaccgatat tatttacttt tccaaatgaa
    21601 tttattcaaa ggagtatttt tattgaaatt gatctttttg aattaacgaa gaaggaccgc
    21661 gacacagatt tgtcacgatc cttctttttt atacctacaa gtaaacagat gcgtaaacta
    21721 atttatacga tcattctgcg tattgaagag taaggttcac attttttgga ctctgattgt
    21781 tttcccctgg attaactggt acggattctc cattcgcttt gatcgttgca ttgcttgctg
    21841 caccaatcgt gatggtcgca tttgttgctg tttccggtaa cacggtactc tgtgtttcat
    21901 ttgctgccag tgtcccttga taaacatagg cattgtctac tagcacacct aaccatacac
    21961 gattgacagc agtaaattca agggttacag gcttggtagc gtctgtgata tttactgcga
    22021 tggcactgcc agaatcttct cctgtagcta ttgccatttt cttttcttca cttgattttg
    22081 ttgttgattc tactgtagaa gactctttgg tctgcgtgct ttgctctgag gaagaggact
    22141 cctcgactga tccttctact ttaagcgaag aagctgtgtc tccgattatt ggatcagctt
    22201 gacgatcttg ccaagtcata tagcccacga caacgacaat cgccaaagca accaatccta
    22261 ataaaatgac aggaagactt gtccaaaagc gacttggatg cgattcttcc tgatgcattg
    22321 cttttctaga agtacttact gtttcaggct gcggacgttc agggaccgat cctgtcaatt
    22381 tgcttttccc atcaaaaaca tcgactaaat ggtctccatc ttctcctaca gcttcagcgt
    22441 attgccgaat aaatgcccgc acgtaaaatt taccaggcaa ttggtcaaaa tcatcattgt
    22501 cgattgcttc caaataacgt ttttgaattt ttgtaatctg ctgtaattca tctaaagata
    22561 tttttttatt caggcgtgct tgccgtaatt tttctccgat ggtttcaaaa gccactcgtt
    22621 catcttctcc agtctgtttg attctccgaa gcatctgctg ttgcaacgaa agacgttatg
    22681 tttgggtgct gtgacaaaag tcatgtcaca gctccttttt tccgaataaa cattgttctc
    22741 ctgccaactc ctcggtcaca agtcacaata tccaataaat ataagaagct gttttttgaa
    22801 cttgttcctt gtgactcgga gttaaacggc aggctcacga cctctttctt aaacggtgtt
    22861 caatcagctg ttcctcggta ttagctcaaa aaccggcaaa atataaggag atatttttcc
    22921 gtatgtttct ctaatactca ggtcaaaacg ctgatttcac aacctcttcc ttaaacggtg
    22981 ttcaaaagct tgcatctgcg gtaataagtc caaccaagtt aaaaacatta agaagctgtt
    23041 tttacttggc tgttcttatt acttgatgca gggcagcttt ttcacaacct cttggtacac
    23101 ggtgttccag aagtagcttc ttcggcaata agccgaaata tcacaaaaat ttgagaagca
    23161 attttcgtaa attccttctt atttcttgaa gctgaccact tctgtcacaa cctctttgat
    23221 tacttcgttt gattttattt taatataagt tgattaaaag agagcatgat ttgttttatt
    23281 ttctcactaa tttttccaac acaactaaga ataccataaa agctgatttt ggaggaggtt
    23341 cctactacaa gtctaaaacg aaatttaaga cttttcctca taaaatactg gtttattttg
    23401 gtctcatgta aaactcgctg aaggcctctt cacttataaa tgcttcccca gctgccagta
    23461 cgtctttcat ttggatcgaa tcgatgattt caggaagatc aaataaagtt cgatcgccaa
    23521 ataaactttg cgtaaattga ttggcaatat attcgatcga atttaatgat tggaaatatt
    23581 gtccaagcat tttcttcttc agcaaatcga gatttgtttc tgacacttcc ggatcatcag
    23641 cgaatccaag aatgatttct ttgacttttt ctgctgcttt ctctggttcg tccgtatctc
    23701 cgctgaagtc cgcaaagtga aattcacgat ccaagctgaa ttcaaaacca aagctgtcat
    23761 cgataattcc ttgattgtac atcgctagat agtttcgaga agtattgcct aaaatcattt
    23821 ggaacaacag attgattgct gttttatagc gtaacagttc tgttccttct tgcggcaatg
    23881 tgtctaatcc tttaatacca agtacaaatt tatctcgtgt aatggctgct tccaatgcac
    23941 tttgtttgat gatttctttt gtgttttcag ggaaataacg tacaatttct tgctttggag
    24001 ggaaattttt tgcttcttgg ttttcccgaa taagtttcat caatttctca ggctccatct
    24061 taccaactac aaataaaacc atattgcttg gctgataaaa cgtccgatag cacgtataca
    24121 agtcttgagc tgtgattttg tcgatacttt caaccgtgcc cgcaatatcg atatgcaatg
    24181 ggtgtgtagg atacaagtta tttagtatgc caaaaaacat ccgccagtta gggtcgtctt
    24241 catacatttg gatttcctga ccgatgattc ctttttcctt gtttacagtt tcttctgtga
    24301 agtaaggtgc ttgtacaaaa tcgatcagag tcgtcagatt cttttctacc tgatccgtcg
    24361 tagaaaacag atagctggtt ttcgtaaaac ttgtgaaagc attggcggaa gctccttgtt
    24421 tcccaaataa ttgaaagaca tcaccatctt ctttttcaaa caacttatgt tctaaaaaat
    24481 gggcaattcc atctggaact ttcacctttt ctttttcacc atagggaata aattcgttat
    24541 cgatcgaacc ataattcgta ctgaacaaac catatgtctt gtgatagtca tttttaggca
    24601 acaaatacac ggtcaaaccg tttggcagta cttcatgata aagtgtttca ttgatttgct
    24661 catattctgt tttattcatt tgcatttcct cctgctaaaa agaagattgc ctgcaattcg
    24721 atttgctcag ctacttgttg tatctctttg atcgttacgc tctccatacg tttcaaccat
    24781 tcttcatcag ataattttgt ttccggcagc cagctgtcca aaaaagaagc ttcgattgcc
    24841 gcttgcggag agtctagaga aagcagatat tggtttctca gcattgcttt tgtctgagac
    24901 agttccaact ctgttatttc accatttcgc aaactttcta attgctcgtg aatcagatga
    24961 agtacttgat ttcggttctt ttcatcgata ccggtttgga cactcatgaa tcctcggaac
    25021 gtatccacgc tactagaggc ataataagct agactttctt tctctctgac attcatgaaa
    25081 agtttagagt gaggaaaacc gccaaataaa ccgttaaaga ccattagcgc aaaacgttct
    25141 ggttcatcgt aatacacatt tgtctgataa gctaggttca gctttgcttg aacgattggc
    25201 tcacgtactt gtcgttcctt cacgatattc acttgaggtt gggtataaaa cagatctgga
    25261 taaactgttt cccgcgactc aaatggtaat tgcccaactg cttcagctgc tttgtccgga
    25321 tcaacatcgc cgacaacaaa aatgtcgatt tgatcatttg ccatcatttc ttgatagtag
    25381 gacgctagcg aactagcagt gatcttgtcc aaatcttcga ctacgcccaa ccctgggatc
    25441 ttttgttccg ggctgttttc aaaataaagt tcttgcaagg cataggaagc aaaagtttgt
    25501 ttatcttcct tcaaactttc caaatataga cgcagattgt tcttttccaa gtcaaacgtc
    25561 aactgatcaa actgatgatt tttaatattt ggataaaata aaacctcttt taaaaaatct
    25621 accgcttgag aaaaaaggtt tggatcattg acatattcac cattcacaaa actgatccct
    25681 gcgtttagcc aatgtaaatt tccttttttt ctaactgata atccaaagct tgcgccataa
    25741 agctctgcaa gttgcgcact taactttgtc tgatccggat aattcaaact atttgtttcc
    25801 aacatgctgc tgagaagtga acgtttcgtg atgacttctt gttgcagacg cgcagtaaaa
    25861 cggataaaaa tccggatcgt tttgtattgt tttgttggta agacatgaag attcacgcct
    25921 tctgccaatt gatacaccat atttatatgc tccttttcac agttgattgc ccgcttactc
    25981 ttttaatggg tcaacctgcc ttttttactt attcctctgc ttgaaattta taagttcagg
    26041 caattcgccg ttttttctaa atgatgttac actttatagt atagcataga tgttttttat
    26101 caaaagaaac agacggctaa aagcgtatat tgttttttta ttttttattt ttcgatatac
    26161 taaagacaaa taaaagaagg gagggtcatt catgatcaaa gaattcaaag agttcatcat
    26221 gcgtggagat gtcttggatc ttgctgtcgg cgttgttatt ggtagtgcgt ttacaagcat
    26281 cgtaaaccaa gtggtgcaag gcttgatcac accactaata ggttggtttg tcgcaatgat
    26341 cacaggtact tctgatttag aaggagcact ttcaattctt gactggtcgc cgacaaaagg
    26401 cgtcacattt gcgtttggta acgttattag tgctatcatt acatttctga tcactggttt
    26461 tgtcttattc ttagttgtca aagcggcaaa ccgtgcgaag aatttacgct ccaaagaaga
    26521 gcaagtggaa gtggaagaaa ctcctactgc agaagattat cttagtgaca tacgcgatct
    26581 tcttgccaaa caagtggcag aagacaatac acatccagta gagcaaacaa atctttccga
    26641 tacttctaaa taataaagaa tctaaaaaaa agaaagccga ttttcagtgt cggctttctt
    26701 tttttagatt cttaacttgc tacttgttcc tttttcatgt cgatatgtgg aatatcatct
    26761 tccaaataca catctgagat tgccttgaat ccaaacgact cataaaaagc ttgtaggtat
    26821 tcttgtgcgc cgatcacgat tggtttttct ggaaaatttt tctggatcat gttaatcgtt
    26881 tcttgaacaa tctttcttcc taaaccatct ttacggttgt cctgatgaac aaggacacgt
    26941 ccaaaatgga tactctccgc ttcttcatat actcgcgtgt aggcaaggat cttcccatca
    27001 gtatcttgaa aaaacgtatg ccaagcttgt ccatcaatgt catcaacttc ttgataagga
    27061 cactgttgtt ccacaacaaa aactgcgatt cgttctttga cgatcgcgta aaactctgct
    27121 gttgacaatt cttcaaattt ctttacctga tattccacta agcaaacgcc ccctgctttt
    27181 ttattcttag cataccgatt cgcacacaaa aaagcaaacg aaccttacga atctcaggct
    27241 cgtttgcttt ttaaactgct tcagttaaaa attcgatctc aactgtccga gtaagtacat
    27301 ctgaatagct gtaagatact cgttcaaaag aattttcttc aggatccaaa tcaacaacga
    27361 atactgaagg ataggtttct gttaaaacgc cgcggcgttc tgtttgacgc tttcttcctg
    27421 tctgagcaac caacatgatt gggctgccga tacgaccttc taaatctttc ttgattgaag
    27481 ctaaagttgt tggcatacag ttcacctcta ctatcaacta taccacatat ttttaaaatt
    27541 ttcaagttta ccataaaaaa aaaagaaatg caataaaaat aaataagaag ctcattaaga
    27601 tttttctaaa ttattcctca ttataaaatt tcaagtgttt ttttattttg agttttactc
    27661 tcccgtaagc gctcattact tgcttgtgat ccattgctaa acattcagcc atgtctacaa
    27721 aatcaacgcc ttgcatataa taatgaaaaa ttttagcttc tatttttgaa aactggattt
    27781 cgcaattttc gattgcttct tttaataaaa gatgctgaat cgctaaaggt tcttgcaatg
    27841 tgatctctgc taaaaagtct ggtccttctg tctctatttt ttggtcgatt gagacttcat
    27901 ctttttgatc acgacgcttc agcgcgttct gcttcctcaa cagagaatag atttgattgc
    27961 ttataatgct tttataataa cttccaaagc taacaccttt gcttttttcg taagttctca
    28021 atgcctgata taaagcgatc cttgcttctt gttcccaatc ctcagaaaca taatttctta
    28081 aataataggt gtttttcaaa cgtagtaaaa gtggaaaata tttttgatac agggcagcaa
    28141 atgcttcttc gtcaccatta cgtgcagcgc gcaataactc ctcagacata aaataattcc
    28201 tccataaatt cgtttatgga ggaatcttat catcaatgat tcatcgaact gattagaacg
    28261 atatgttatt tattttttct cattaaatcg tccaattttt gggacaattt ttttaactgc
    28321 tcttcattcc atggagaatt acgtcggaaa tcaataaaat gcatatcttt attttcttgg
    28381 gctattgttt tttccgtttt ttttatcgtc ttatataatt cataagcaga agttcgtaat
    28441 gctccttggg aaaagatcat ccactgttct gctaaatcgc ttgtcgccac tgtcacttgt
    28501 gtcaaacggt cattcagctg accagcgatt ctctcgatat aactgtcagc cgtttcgtct
    28561 tctttcgtaa aaacaacatc caactggtat ttcttataat tttgttggat gcccggaact
    28621 agttgggcat cgaagacaac gatgacttcc attccttcat atttcgcata atttgataaa
    28681 cgatgtaaaa gagcttctct tgcatccgcc attttgtcct gctttttaag ctggacaagt
    28741 tccggccacg aaccaatcat gttgtagccg tctacaatca acagctgttt tttcatggtc
    28801 tactccccct gacgttggga aaaagcctga tacataagca aaccagcagc aacactggca
    28861 tttaagctct ggacgtgccc ggtcatcggg atcgtcagca attcatccat ttcttttttc
    28921 aatcctggac tcattccttt gccttcatta ccaatgacta aagcaattga tcctttggca
    28981 ttccattttt ggaagtttgt gccggtcata tctgtgccaa atacccaaaa tcctgtttct
    29041 ttgagctgtt gcacagcttg taccaaattc gtcacgcgtg caacagggac atgttcgact
    29101 gccccagtgg aagtctttgt tacgataggt gtgattccaa ctgctcggtg ttttggtatg
    29161 atcacaccat cgacgccact tgcgtctgct gtccgtaaaa tcgacccaaa attgtgtgga
    29221 tcttcgatgc tatccaaaat caaaaagaag gggtcttctt ttttctcttt tgttcgttca
    29281 atcagttggt caagggataa atattcataa ggtgtaatcg caagaacgac tccttgatgc
    29341 acgccgtgat cgctcaaagt ttctaatttt tgtttaggaa cccatttgac tggcacagct
    29401 tgttcacgtg cgatttcttt cagttcttct actttttctc ctcgtgaatc ttcttgaaga
    29461 aagagtttat tccctcgccc ttgttgtagc gcttctactg cggcatggtg cccaaagacg
    29521 aaattatctt ctaatgcttc ttcattttga tcagaaactg actgatttcg tccagtttgc
    29581 tttttatttg aatatctatt ttgttttttg tcttcaaatc cacgtttcga ttgatgtttg
    29641 tttgttcttt ctttacccat ttttttcacc aactttctga atacaccagc ggatcaattc
    29701 ttccatccgc tcggtttgtt ttgtcaaatg cagatagccc atgagcgctt cgaaccctgt
    29761 tgcgacccga tacgtcgtaa catcagcatt ttttgcgctc gtatggcttt tagcatttct
    29821 tcctctgcga taataaagtt cttcttcttc tgtcaaaaga tgttcttcca gcatttgctg
    29881 aatcaaaaag gcttgtgcat tcgcagaaac ataattcgtt gccgcacgat gcagcttatt
    29941 gggttttgtt tctccttgat caatcaggtg gtcacgaaca tagatttcgt aaatcgcatc
    30001 tccaacataa gccaaggcta aaccgttcaa ttgtgtgtaa tctctcatgc ttctcttctc
    30061 catcgggttc cttgcggtgt atcttctaat aagatccctt tttctttcaa caaatcacga
    30121 atttcgtcgc ttcggacaaa atcacgattg cttcttgctt gatttcgttc ttcgatcaat
    30181 tgttcaatct cttcatctaa taactcttct gctgtaaata aaataccgaa gatcgaaagc
    30241 cattgcgaga ataaagcttc tccttgtgcc aagacagcgg cagaaacttt cggctggtct
    30301 agataagtgt tcagccactt agcaagctca tagaccactg tgatcccatt tgctgcatta
    30361 aaatcatcgt ccatttcttc gatgaatcgc tgttctaaat tttctaacaa agcgatttta
    30421 tccgcatcat ctgccaaatt ctctgaggca gtttcttggc ggaatttcaa attgtcaaac
    30481 gtattcttca gtcgttgtaa attggtggct gcttctttca tcgtcgtttc actgtagcgg
    30541 atcggacgac ggtattgtgt ggtcgccatg aagaaacgca agacttgtgg atcaacgttt
    30601 ttgatcattt catgtacagt gatgaaattc cctagagatt tactcatttt ttcatcgtct
    30661 tcgccaatcg ttacatagcc attgtgcatc cagtaattag cgaatttttt ccctgttttc
    30721 gcttcacttt gtgcgatttc attttcatga tgaggaaatt ctaaatcttg cccgccacca
    30781 tggatatcga tcgtttctcc taaatgtttt gttgccataa cggaacattc aatatgccaa
    30841 ccgggacgtc ctttgcccca tggtgaatcc caagaaatct cgccaggttt tgcttgtttc
    30901 cataaagcga aatctaatgg gtcttctttt tgctgctgtt cttcccctgt acgctgactt
    30961 gctccgactt ccagttcatc gatggattgg tcacttaatt tcccataatt ttcaaattta
    31021 cgggtacggt aatacacatc acctgaagat tcataagcat agcctttttc aaccaacact
    31081 tgaataaatg ctaaaatatc tggcatatga tccatgactc ttggatgcag tgtagcaggc
    31141 tcgacattca acgctttcgt atcttcttca aatgctcgga tgaaacgatc agcaacttct
    31201 ggtgctgtaa tacctaattc gtttgctgta cggatgattt tatcgtctac atccgtgaaa
    31261 ttcgatacga aatcgacttt atagcctcga tattcaaaat agcgtcgaat tgtatcgaaa
    31321 gcaatggtgc tacgagcatt tccgatatgg atataattat acacagtcgg tccgcagaca
    31381 tacataccga catgtccctt ttgtataggg atgaattctt ctttttttct ggtcaatgta
    31441 ttgtagattt ttatcattct gatctcctca ctttttctcc tttgattcga acgacttttg
    31501 ctggtactcc taccgctgta gcgtcgtctg gaacatcttt caacacaacg gcacctgcac
    31561 cgattttggc gttttttccg atcgttaccg gtcctaatat ctgcgcattc gcagagagca
    31621 tggctccttg tttaacagtt gggtgtcttt tacccgtttc ttttcctgtg ccgcctaatg
    31681 ttacgccatg gaataaaatc acatcgtcct cgatttctgc ggtttcgcca atgacgattc
    31741 ccattccatg gtcgatgaac acgccagttc caatcgttgc tcctggatgg atctcaacac
    31801 cagttaggaa acgccagaat tgagcattga tcttcgccaa taaaaagagc cggtgctgat
    31861 ataaaaaatg agagaaacga tgccaaaaca aggcatgaaa accagggtat gtcaaaacga
    31921 tctcagctgt cgaacgtgca gccggatcgt ttctctttgc tgcatcaatc gctcgggtaa
    31981 accaactcat gactttccac tcctttcgta agaattttat gtaggaaatc atcttcttat
    32041 aaagaaaaga agcgcctttt aaataagttt ccttatcaaa agacgctttc cgcgtggttc
    32101 cacttttctt cataatcaat gattatctct gacagctaac gcctgttata cgttcttggc
    32161 tactttgttt cctataaaac agtttttcct gttttctgtg tttcgccaag accactccca
    32221 gaggcatttc ggcaaccatt cattgatacc ttgcaccacc cggtatctct cttgtaatga
    32281 tcagctgctt acttttttct gttcatcgtg tttagttcag tacttgattt aaatgtgcta
    32341 atgatttttc acgaccaagc aattcgatcg tttcaggcaa ttctggacca tgcatttgtc
    32401 ctgatacagc tacacggatt ggcatgaaaa gattttttcc ttttacgcca gtttcttttt
    32461 gaacagcttt gatggcagct ttgacagttg gagcatctac tacttccatt tgttctagct
    32521 gtgctttgaa tgcgtggaga acagtaggaa ctgtttcacc agcaagtact tcttttgctg
    32581 cttcattcaa tacaggatgt tcattgaaaa atagcgtaga cagatcaacg atttctgcag
    32641 catagctcat ttgaggttga tacaggctaa cgatcttctt cacccattcg attgtctttt
    32701 catctgggtt ttctgctaca cgtccatcag cgattagata aggcagacac atgtcagtaa
    32761 atgcatctag atccattgct ttgatgtaat ggttgtttac ccattgcagt tttttcgcat
    32821 cgaaagctgc gggtgattta cttaggcgtt ttggatcgaa cattttgatc aattcttggt
    32881 gttcgaagat ttcgtcttcg cccacaggtg accagcccaa taatgcaata aagttgaaca
    32941 ttgcatctgg tagatagcct aattcgcgat attgttcgat aaattgcaag attgattcgt
    33001 cacgtttgct tagtttttta cctgtttcac tgttgatgat caatgtcata tgtccgaagg
    33061 ttggtggtgt ccagccaaat gcttcataga tcatcagttg ttttggtgta ttggcaatat
    33121 ggtcatctcc acgtaaaacg tgagtgattt tcatcaaatg atcatcgacc gcaacagcaa
    33181 aattataagt tggcatacca tcgcgttttt gtatgacaaa gtcgccaccg atattatcgg
    33241 attcgaacga aatagcgcct ttcaccatat ctgtaaatgc gtattctgta ttgcgaggca
    33301 cacggaaacg tacaacagat tctagacctt gtgcttcttt ttctgcttgt tcttcaggtg
    33361 tcaagttcgc acatgttcct gcgtaatgag gcatttctcc tcttgcgcgt tgtgcttccc
    33421 gttctgcttc taattcttct tctgtgcaat agcatttgta tgctcgattg ctagcaagca
    33481 gctgatcaat cagcggttga tagatttctt tacgttcaga ttgacggtaa gggccgtatt
    33541 ctccaggatt ttcaggagat tcatcccaat tcattcccaa ccaagcaagg ttttccaact
    33601 ggcttttttc gccatcttcg atattacgtt tttggtcagt atcctcaata cgaataataa
    33661 agtctccatc attgtggcgg gcaaacaaat aattgaataa tgcagttctt gcatttccaa
    33721 tatgcaggtg cccagttgga cttggtgcat agcgtacgcg tactttcgtc attttcttcc
    33781 tcttctttca aactagactt tgactaacag caaaaattcc gtcagttacg gcttctcaaa
    33841 tatcatttat ttaaagccac tcagcacaaa ttttaccttt tctaaggtaa atagtaaagc
    33901 caactggttg aatttcctta ccagttggct gaatttcttt tttattttga ttgtttagtc
    33961 tttttctctg tctctttttt attgtcgatt cctcgtcctg catgtgcagg tttagcaaag
    34021 atcatgcgtc cagcagctgt ttgaagggca cttgttacaa cgacttcgat acgttcattc
    34081 atgtaatgct gtccatcttc tacgacaacc atcgtgccgt catcaaggta ggctactcct
    34141 tgttggcgtt ctgtcccggc ttttactact agaacattca tcgtttcacc agggatgacg
    34201 actggtttta cggcatttgc caacgcattg atattaagaa caggtacatt ttggaattca
    34261 gagactttat tcaagttata gtcattggtt acaatgacac catctaaaag cttagccaat
    34321 ttgatcaatt tgctgtctac ttcactgata tcttcaaagt ctccatcgta catttcgaca
    34381 gatataccct cttctttttg caaggcattt aggatatcta atccgcgacg accacgcaca
    34441 cgtttcaaac tatcccctga gtccgcgatg tattgtagtt cgtaaagaac aaaattaggg
    34501 atcatcaagg ttccttctaa gaatccagtc tttgtaatat cataaatccg accgtcaatg
    34561 atcacgcttg tatccaagat tttatattta tggaaatttt ctcctgattt tcgttctaac
    34621 agttgactct caacttgact agctgtttct tgctcgattt ttttgcttcg tgaaccaaaa
    34681 actttcttcc attcttcgat tcgtgtcgtt cccattctca atcccagata gcctaagatg
    34741 atcatcagta aaatcggcaa tacactattg acgaatggaa tttccatatt gtaaagaggg
    34801 gtcgagatca caacacctaa agtcaatccg atgatcgcac cgatcgcacc gaagagaaga
    34861 taagtcaagc tgacctcact tagtttttgt tctacttgtt tgataatagc tgagatatgt
    34921 ttggccaaca gcaaagataa taaaaagaaa ataagtgcgc ctaacaggct gttggtaaat
    34981 gtattattca gccatccgtt tgactgttga ccgattgcct gccaagctga gggtaaaaat
    35041 gaaataccca agcttgcgcc gacaatgatc atcagcaaag taatgacacg tttttgcatc
    35101 gtttttcctc cgtttcgaca atcatttatt agttagcgga acacacgctt caacgtttca
    35161 gccaaagttg ctactccaac tatctcgatt ccttttggcg cttcccagtt acctaagttg
    35221 tttttaggta ggtatacttt tgtgaagccg agtttttgga cttctttgac tcgttgttca
    35281 atatgactga cacgtctgat ttctccagtc agtccaattt caccgatgaa acattccgtt
    35341 ggctgtgttc ctttttcttt atagcttgaa gcaatactga cagcgatagc taaatcaatc
    35401 gctggttcat ttaattttac cccacctgca gcttttaagt aagcatcttg attctgaaga
    35461 agcaacccag ctcttttttc cagcactgcc atgatcagag atacccgatt gaaatcaaga
    35521 cctgttgttg ttcgtttggc atttccgaac atagtaggtg tgactaatgc ttggatctct
    35581 accaaaattg gacgtgtccc ttccattgcc acaacgatag cagagccagt tgcaccgtct
    35641 aggcgttctt ctaagaaaat ctgtgaagga ttagcgactt cttccaatcc atgctcatgc
    35701 atttcaaaaa tcccaatctc attcgttgag ccaaatcggt tttttactgc tcgcaaaatc
    35761 cgaaaactat gatgttgttc accttcaaaa tataacaccg tatccaccat atgttctaac
    35821 attcttgggc cggcgatcga gccttctttg gtaacatgac cgacgataaa aatggctatc
    35881 ccatttgttt tagcgatttt gagtagttct gcagtggttt ctcttacttg gctgacactt
    35941 cctgccacac ttgtgatgtc tggctgcgtc atcgtttgga tggaatcaat gataacataa
    36001 tcaggggaga tatgttcgat ggcacgactg atttcgttca tatctgtttc agcgtataga
    36061 taaaattctg tgttgatact tccgaggcgt tccgcgcgta attttatctg ctctgcgctt
    36121 tcttcgccgg atacatataa gacttttccg cctatggctg ctaattgctg agaaacttgt
    36181 aacagcaaag tggatttccc gatacctgga tcgccaccaa tcaagaccat agaccctggc
    36241 accacacctc cgcctaacac acggttcagt tcttctaatt ttgttttgat ccgaggttct
    36301 tttttaggga cgacgtctgc gatttttgtt ggttttgctt tttctcctgt caaacttgtc
    36361 cgagttctgc ggtccgttgt atcttgttcg atttcttcga ccatcgtatt ccattttccg
    36421 caatttgggc agcgtcccaa gaacttaggc gacacatacc cgcaattttg gcaaacaaat
    36481 tgtacttttg atttttttgc cattgtaccg cctcctttta tcctaatcat gagacattaa
    36541 atcaagctta agtatcttta acgttttatt tactggaaga accaaatccg ccttgacgtt
    36601 gagcagtcgt ttgatcttga tctgctttta aaaacggcaa aaagatccct tggccgatac
    36661 gctcgccttt tttgatcact acatccttga aaccaaagtt ggtgaattgg aacatgatat
    36721 ggccttcatt tgcctcatta ttgtaataat cactgtcaat cacacctact ccgtttgtca
    36781 acactaaaaa ccgcttcaac ggattgcttg aacggttagc aagctgcaaa aattcatctt
    36841 ctcccatgta agctttgatt ccagtaggca cgagggttgg tttcaattgt ttttcatttt
    36901 ctgatacatc ttttttcaat ccatctgcga ctgtttccaa cccctttttc cagcctgctt
    36961 tccagatact tggaatcacg acctcttctg ctgcttcaaa atcatagcca gcagcatgat
    37021 gtgtagcgcg ctgcggtaga ttgatatttt gatctttata tttagaaata acttcaaatc
    37081 ctctttttct caccggtttt cctccctaaa taaactactc ctattctaac atatccgagg
    37141 ctgtaaaaga ctttctttac aaattcttca agaaattctg ctatcttaaa gtaaaccatt
    37201 aattcgttct ttttccaaac gactgcaagt tgtacaaaaa aactattttt tacatgactt
    37261 tactcgtcaa aacaagtaga atagaacgaa attaatgagt ggatatttga ttgaggtgtc
    37321 acatgcgtaa agaaattaaa aatgcaaaac gaattattgt caaagtagga acaagtacat
    37381 tgatttatcc caatggaaat atcaatcttg cggcaatcga tcagttagct tttgtccttt
    37441 ctgatcttag aaatcgggga aaggaagtga tcttagtctc atcaggagct gtaggcgttg
    37501 gtatgcataa attacatttg tcagaacgtc cgactttgat tcctgaacag caagctgcgg
    37561 cggctgttgg tcaagccgaa ctgatgaata tctataatca aagattcagt gtatataatc
    37621 aacagacggc acagatcctc gtgacaagag acgtggtaga ttatcctgaa agtcgtaaaa
    37681 atgtgaggaa tacattggaa cagcttttga ttatggacac gatccctatc gtgaacgaaa
    37741 acgatactgt agcagtggat gaattagatc atctgacaaa atttggcgat aatgatcagc
    37801 tgtcagccat catggcaaaa cttgtcgcgg cagacctttt gatcgtcctt tctgatatcg
    37861 acgggtttta ttcagataat ccgactacaa atcccgaggc tcagatgtat cgctatatcg
    37921 ataaaatcga tgaaaagatt ctggcacaag caggtggtgc tggtagcaca tttggaacag
    37981 gcggtatgca gagtaaatta aaagccgctt ctaggatatt tgaagcaaac agcgcaatga
    38041 ttttagcaaa tggaaaaaat ccggcaatta tttttgatat tcttgcagga aaagaagtag
    38101 gtactttatt taaggaggac ttgaaatgac tgacttgatg caattaggac aacaggcaaa
    38161 agatagcgcg caacaactag cacttatgcc tacaaaccgc aaaaatgagc tacttgttca
    38221 aatggcacaa accatcaaaa agaatcaaca agcgatcatt gaagcaaatc ataaagactt
    38281 agaaaaagca gtcgaaaaca atatcagtga aacgatgcaa gaccgcttgc agctgacacc
    38341 tgagcgaatc aatgccatgg ctacagagat cgaaaaaatt gcttcgttag acgatcctat
    38401 tggaaaagta gatgagatgt ggacgaacac cgacggattg agaatcggca aaaagcgcgt
    38461 gccactaggc gtgaccggca tcatttacga atctcgtcca aatgtcacga cagatgcagc
    38521 tagtctagca ttcaaatcag ggaatgccgt tatccttcgc ggtggcaaag aagcattctt
    38581 ctcgaatcaa ttattagtcc aattattgca gcaagtactg gtcagtgctg gcgaatctcc
    38641 ttatgccatc cagtttgtcg atgatacttc tcatgaaact gcaggacagt tgatgcgatt
    38701 gacagaatac ttagatgtgc tgattcctcg aggcggagca aaattaatcc aacgagtcaa
    38761 agaacaggca acggtaccta tcattgaaac aggtacagga aataatcacg tatatatcga
    38821 taaagaagca cagttatcta tggcagtgaa catcatcgtc aatgcaaaag cttcccgtcc
    38881 atctgtctgt aacgcggcag aaacattgct gatccattct gagatcgcac cttttttctt
    38941 gccagctatt gaaaaagaac tggtagaaca cggggtctct ttacgtgcgg atgctcgtgc
    39001 gttagaatat ctagagacgg ctgctttagc agaagacaca gattgggata ctgaatatct
    39061 agattatatc cttgctgtca aagtggtcga ttctttggat gaagcaattg cacatatcaa
    39121 tcggcataat actaaacatt cagaaacgat cgtgacagat agttatgcgg ctagtcaacg
    39181 tttcttaaat gaagtggacg cggcggctgt ctatgtcaat gcctccactc gttttacaga
    39241 cggatcggta tttggttttg gtgcagagat tggtatctct actcaaaagt tgcatgcccg
    39301 tggtccaatg gggttaaatg aattaacttc cacaaaatat atcatttatg gcgatggaca
    39361 aatccgcgaa taatgtttcg tgtgaaacat tattcccgcc ttttgccttt tttctgtaaa
    39421 ggttctatcc aactagaaag gtgtcaatat gtttgaaatt ttaatgattt tttttattta
    39481 ccttatttct ctgaatatcg ctgcttttct gggagtcggt attttatccc ttttctttca
    39541 attcaaaaaa cgaagcatag ggagtcaacg ggaaaaatgg tcgcagtatt ttgacaaaat
    39601 cgggcaaaaa gggctggtta cacgcttgca cattagttac atggttgcat tatgcttatt
    39661 agcgacaatc aattactatt cttttttcga tcattcaatc gcttatacga ttacgctact
    39721 gattgctggg atttttcact tatcttataa atatcagctg aataaaaacc acttgaatcg
    39781 gactttccgc taaaaaatat ccgtacgata agtagagtgc cttgaagatc ggcaaaaaac
    39841 tgccggactt tttagaggct gtgacaaaga ttttgtcaca gcctcttttt ccatataaac
    39901 ggcgttcgcc taccagctgc ctggtaaatc tgtttcctct tcgttaagaa gcgaaaatcc
    39961 gtcaaatgtt tcgccatcat aataacgaag cagctcatcc atggacaagt tcatcgtttt
    40021 ttctttttct tcttccgctg attcagccag tagctgttcc cgatacacct gatacatacc
    40081 agctattttt tgctgcatcg cttttctagt ttcaccttcc gcattgatta ttggcaattc
    40141 tttgatatag ccacgataaa tcaaccgatc atctgaaaat tcaatgggta attcaacgag
    40201 tgtcaacccg acttcctgaa aatattcttc cagcatctat tatcccccca ttctttttct
    40261 taaatgaatt ttagcttacc tactgaaaat tttccagttt cattattttg agaaaaaaag
    40321 ggaatgtgac aaaaatcgtg tcacatcccc tttttccgaa taaatggtgt tcttctgcca
    40381 actcctcaat cataagtcac aatattcaac aaacatgaga aactgttttt tgaaattgtt
    40441 ccttgtgatt cagagttaaa cgacagtctc acaacctctt ggtaaacggc gttcaaaagc
    40501 ttgcatctgc ggtaataagc ccaaccaaac gaaaaatatg agaagctatt tttgtttggc
    40561 tgttcttatg acttgatgca ggacagcttt ttcacaacct ctgatttctt attcttcttc
    40621 atttgtagca aaataattac ggtgataaat gatacaacat acactgataa gaacaatggc
    40681 acctgcaaaa taaaacgcat agctttcacc aatatgttca ccaatcacac ctgcaataaa
    40741 tggtgctaaa gctccaccga aaaagcggac aaaactatag ctggacgaag caacgtttcg
    40801 ttgcagacct ggtatttcca tagcaatcgt cgtcaacagt gtattgataa ttccttggaa
    40861 aaatcctgct aacacaatgc tgatcggtac aaggactggc atagaagttc cagctcctaa
    40921 taacagcaaa caaataatga ataagacaaa tgctgctaaa attgtccgat aagtcgtaaa
    40981 cttccgctca agagccggtg caacgaaaat cgaagcaata gccagaagca caccccagcc
    41041 aaaaaataca aaaccgactt ctaattcaga atagccaatc aataaaaatg gcgcatacgc
    41101 aagtaaagta aagaatccga aattatataa caatgcgatt agtccaactg aacgaagttt
    41161 atgattgctt aacgctttga caccttccca aaggcctact tttctctttg gtttctcagt
    41221 ttcaggtaaa agtaccgcta gggctataaa accgcaaaac atcaaaaatg ctaccccaaa
    41281 aaatggataa cgccatgaac cactgcccaa gaccccaccg actagagggc caacagccat
    41341 tccgcagcca agtgctgctt catacatcat gattgctttt tctgtgttac caactaaaat
    41401 actgacgatc gttgctaaag cagtagagac aaataaagca ttcccgacac cccagccggc
    41461 acgtaaccca atcagcattc cgatattccc agataatccg ccaagaccag cgaatacaac
    41521 gatgataaac aatcctgtca tcaatgtttt ttcaaaccga tccgactaga taagaaacct
    41581 gtaaatagca tcaccacacc agtgactaac atgtaactag taaataacag ggtcgtttca
    41641 gctggcgtag cgtttaactg tgcagcaatc gtttttaaga ttgggtctac tagacccact
    41701 cccataaaag cgatcataca ggtagctgct acaactagcg ctgaactttt cccctttgtt
    41761 tcttcatttg tttgttcttg tatatctatt tgattctcca atatttccat ccctttctct
    41821 ctattagcat catacatgat ttattttaca tgtaaatatg cacatgtaaa acgtggaaac
    41881 tttactgtga tataataaag aaaataagac gagaggtagg atttttatga atactttagc
    41941 ctatatatta ttatgcgtgc ttttatccaa accacgttct gggtatgaat tgaagcagct
    42001 gatcacaatt ttttgggaag cccatcacag tcagatctat acaacgcttg ccaagttaga
    42061 ccagcagggt tatgtgaccg ttttggacaa agacgagcac tctcaaaaaa agatctacca
    42121 cttgactgat gaaggacgtg ctcttgtaga ggaatggatc aaagaggaaa ctcccgctcc
    42181 tacgcaaaaa gatgaatttc tagcaaaaat ctatgctttt tcgacgctcg ataaaacaac
    42241 agctactgga ctgctattca ctagagaaca acagctgaac aaaatcatgc aaaaaaatca
    42301 aaaaaaattg aatgacctct cgctagacaa gaaacaagaa tttggacgtt atgttgtgat
    42361 ccagcgcaga attatgcttt gtcagcagga actccaatgg tgtcagcaag taagagaaca
    42421 aatgcagcag ttttttgagt aagggataaa cagaaccttt ctagaaatat ctattgaaga
    42481 gcaaattatc ttcaataaaa gagcaataca gttggaaaag aaaaagcgat ccgaacgaca
    42541 ggccaaaacc tatcgttcgg atcactattt ttctagaact gcattcaaga gactatgaca
    42601 aaaagcatgc caaggccttt tttcaaataa cagtgttcca tcattcatta ctttgaattg
    42661 cttttagcac acttcttgaa agcgggccaa cgatgatcaa ctgcaacggt aaagcggcaa
    42721 tcacattcat tttccaagca ttcatataag cagagaataa ttgatcaggt attccttgtt
    42781 ccatgatcac accgaataaa gacatacatg tcaccattcc taaaaccatc aagcatgaaa
    42841 tagttaagat catttggacc ttgctttctg gatttactgg tagtttaaag gcaatttttt
    42901 tcgccagcac accgatgatg aagacatcca aaatgaaagc caccacgaat ccaggcacta
    42961 gaccaatcaa caaacttgat aaatgaagat cttgatgcag ccataaatta tacgcgctca
    43021 tccccaagac catcaaaaaa cacatcattg ttgtaaaaat tattccttct tttttatttg
    43081 taggcaatct gtaccactcc tttaaatttg tcacgaaaat catcgtagca catttaaaaa
    43141 tttctcgtaa gtactttttt tattttctgc ccttttattt cataaacttc atcagccgta
    43201 cgctcgacaa agtaagaatc atgagaagta aacaaaatcg ttcccggata tatttgcatt
    43261 agcttctcta aagcttcgat cgttgccata tcaataaaat tagtcggttc atctaacagc
    43321 aacacattac ttggcttagt aaaaagcaaa gcaatcgtca gacgggtcgc ttctccccca
    43381 cttaatgtac ataacggttt cgtcaaagtt tcctgagcaa accctaagtg attcagcaaa
    43441 ctacggacaa gcgattctga aaactctgtt tgtctcatga caaaacgaat gatggattct
    43501 tcagatgtca tttgataacc cttttgctga tatacttgaa agcttacttt cggagagaga
    43561 aggattcctt ctccttgttt gcggatatgt tctaataagg ttgtcttacc tgaaccattt
    43621 tcaccgacaa tcgcgatttt tttacctaaa gaaaactgaa aatcaccatt taccagtaat
    43681 gttctcccac ttctttccaa ttggacattt tgtcccatga tgggatagcg gctgtggagt
    43741 tcaagagatt ttggtactgg aaaacggatt tgtttcatct gctgcggctt ggttgtttct
    43801 cctatttttt ggagtcttct ctctaatgtt ttcgcattct tttggatggc tttttgtaca
    43861 ctgtcttttt gtttagagga agacaaccga tccggtctga tttgttgctt tttcttttta
    43921 ctggacactt tttccaactt ttccgcttgt tttttctttt cttggatcga tttttccaat
    43981 cgttttttct ctttcatgat cgactctgct tctcgtagct gagtcttttt ctccaattcc
    44041 ttttgagtga gataggcact ataattcccc gaaaactctc ggatttctcc gtcttttact
    44101 tcccagattt tcgatgctag ctcatctaga aaatagcgat catgactaac aaaaaccagc
    44161 gtaccataat aataacgaag ctcttcaatc agtcgatcaa tactttttct atctagatgg
    44221 gttgttggct cgtctagaag catcccttgt tcataagaag aaagaagacg tatcaactcg
    44281 atctttcgtt cttcccctcc gctccatttc cgctctgaag tttcttccag tcttaactgg
    44341 aaatgactgg ctaattccaa atttaggtcc tttgcttcag cgagataggt taattgaggc
    44401 aggtagttga aggtgatctc tgtttggatt ttcccatgat cgggaaaaag ttcaccggct
    44461 attagtttga gcaaagtcga tttaccgaca ccattttctc ctatgatccc tatacgatct
    44521 tgctgataga cacgaagaga atcaatagat agttctagct ggttgccaaa gctgacttgt
    44581 agatttgtta tatttactgc taaattttcc atatgtttta cactcctatt tcatgtaaaa
    44641 caacaattat cgatactaaa aaagagcaga aaaatctgtt tgcaaaaaaa ctgcatcaca
    44701 tcttttccta ctctgaacga aataactatg actaaatcac caaatctgtc atagctttca
    44761 cctattctac tgtcgttcga aaaaatggac atactccatc catgaaattg ttgtttatac
    44821 atgtcttttg aatttattta gttgttattc aaaagttcga aacgtaattt catcgatgca
    44881 gtcatttttc cgacctcctt ttttattagg ttaccacaca cgattcaaaa aaagcaatag
    44941 ctactgaata gtaactgaaa accttttatt cgaacgtagt gatcttttct ggtgctaaac
    45001 gaacagactc gtaaccttct tctaccgctt ttcctattga taaaataata actggaacat
    45061 aacggtcttt atccaaacca aatgcctctg ccaactgatc tgcttcgaat ccaccaattg
    45121 gatttgtttc atagccatga tcacgcgcaa ctaacatgaa ttgcatagcc gctaagctag
    45181 aatcgacttt gactacatcg ttcatttctt ctcttgaaaa actcttgtaa taaggaatga
    45241 tcgcagctaa ttgttgatct ctgacttctt ttggcatctt ccctgattcg taagcttggt
    45301 tatagatttc ttcgccatat tcgtaacatt gcatatcgcc aaaaatcatg accattgcag
    45361 aagaagtatc attttgtctc gtattgaaac ggatcaaagg acgcaagatt tcttttgctt
    45421 cctcgctttc agcgaccaca aagcgccatg gttgcatatt gacagaagaa ggtgcagtcg
    45481 tcgcttcttt gatcatttcc agcatttctt cgtgtgggat tttgtatgtt tcatcatata
    45541 cgcgaacgga tcttctacca gtcataattg ttgaaaaatc atttttttgt tccattatta
    45601 ttaacctctt tcgtttctgt tgttatattg caaagttggg tattcaattt atctaaaagt
    45661 gttagaaatt gtttcatttc tacatcgctg aaagccgggg atagcacgga acctgtatct
    45721 ttatggtcca tttcacaatg ctcgattttc ttctgggctt tttctgttag cgctacatac
    45781 acttcccggt tgttctgagg atttctctga cgcgaaacat agccatttgc ttccaatacc
    45841 ttcagatgac gagtaactgc tccttgatca atctgcaact tttcttgcaa actgctttgt
    45901 agcaatggat tttcttcttt cagtctcatc atgatctcgt atctagtaag acttataccg
    45961 atattttctt caaagatctg gacgattttt tgatcggcta atttgatttg atataaaagg
    46021 tgactaatct cttctaaaga cataatttcc tcctttctaa taattgactc gtcaacgatt
    46081 gacttgtcaa taatagaata aaaaaagaaa aaagtcaaag aatcagctgt gtaataaaaa
    46141 aaacgctctc aatagaaaag tatagagaaa agaaattttt tgtagaatga acggaaaaaa
    46201 tgataaagaa agcacaacgc taaaaccaag attattgatt cttatcaaac tatagaagat
    46261 agctcttctg cagtagaaaa ttttacaccg ccaaaaattt ccgaaatcgc cttttgcaag
    46321 aatcccgtcg aatattagaa attggatcag tatgcttaaa cagtaataaa aaagttatga
    46381 caagatgttg tcacaacctt ttttgagtaa acggtgttca aaaacttgca tctgcggtaa
    46441 taagttcaac caaacaaaaa acatgaaaat ctgtttttgt ttggctgttc ttactacttg
    46501 atgcagggca gctttttcac tacctctttt taataaccat aaaatcctat tccttcatat
    46561 ctccagccca tcggtgttag ccaatctctt tccttagcac tcaaggtata gtgatgggta
    46621 ccagtttttt catttggatt aaatagtcga taaattggct tggaaccacc agaataaaaa
    46681 cttagacctt cataacgcca accgattttt gttaaagagt tgatctcaga ttgtgccatt
    46741 gtgtaatgat ggtctccact gtaaggattg tataaacggt agacaggttg tccgctgttt
    46801 ggtgcttgcc aagcaatccc ttcatattcc cagcctacag ttggcagata atttttttct
    46861 ccggcattca atgtatataa atgttctcct gtatgacggt tatacagacg atacatcgga
    46921 gaagttgaag ttggtgctgt atcatactgt gtcagattat aggtttcgat tacattgttc
    46981 aatgtagaac cataattagg cgcagtggca taacgacctg ttagccaagc cgtagcatct
    47041 ttgtaagagt tcgtattgct tttccatgca ccggaatagt agtaaacgcc tggctgaaaa
    47101 gaagtcgtct tcaataccgt tacgttatct tgcaatgatt ctttgtacga aggatatttt
    47161 ctaaaagcgg cattcaccgt aatccattgc ccattcacat attccgaagt aggcatcgta
    47221 acagattggc cattatagct tcctttaatc ccaaatagat tgtaattagg ggcagaagcc
    47281 aaagtactgt tcccccagcc actttcaacg atggcttgag caatcatgac tgatgcatat
    47341 aagtcattgg cacttgccaa actttgtgca gttgaggcaa tactatcaat gaacgcttgt
    47401 tgagaattag cagatgagcg agcataaaaa gcatagccag tatagttttc gaattcagac
    47461 aaatctgctt gatgggtatg tgtcaatgtt tgcccatctg tcaattggtt cgtgatttct
    47521 tctgcattct ctggattgtt ctgagcttct gctgatgtac tgtcttcggt ttgtgtttgt
    47581 tctgttgttt cagttgttgg ttcttcggtt gaaattgtat tttctgagac agtagctgac
    47641 tgcaaagtac tctctgtatc gttttcaatt cctgtttctg aagaactcga tgtctgagtt
    47701 gcgacagttt ctgtcgattc ttcagctagc actgttgtgt tggcaactgc tagatttcct
    47761 aaaagaataa cgctaaataa taaattcttt gctttcatct tttttctcct ttgaattatg
    47821 aaacttttcc taaataacag tgtaactaaa aaagtaaaag caagtcaatg tccatattta
    47881 aataacattt gtttcttttt gataaatttg ctttttctac ataaaaagac gtaaatgaag
    47941 aatattcttc tccattcacg ccttaaattg atggtcgttt gaataactat ttaacaagta
    48001 attctctttg gatattatcc gttatggatt atacttcctg tgtcgtcgga cggataatca
    48061 tgttactgac agacatccgg tctggcgttt ctatcgcaaa tgctacagca gaagctatat
    48121 cttcggaggt caatccccat tctttttgcg cttcatgaag ttcaagagca gcctttttgt
    48181 cgctgatggt ttgatataat tcagtttgaa cagctcctgg agagatgatc gtagatttga
    48241 tgttattttg ccgttgctct tgacgtaatc cttccatgat tgcacggaca gcaaattttg
    48301 ttccgcaata aacggcggaa tcaggataaa caacatgtcc cgccacagaa tcagttgaaa
    48361 tgatatgccc agatttttgt ttttccatga ttggaagtac ggcggaaatt ccatttaaca
    48421 cacccatgat gttgatatca agcatatttt gccattcatc acggtgacct tcaactaatg
    48481 gagcggttgg catgattcct gcattattgt acaatacatc gattcgaccg aacttttcca
    48541 tcgctaaatc gataactgct tggacttgtg caaaatctct tacatctgct gtttgaatat
    48601 atagctcagc ttctggtaaa gattctttta ttgcttttag gcgatcttct cggcgtgcag
    48661 ctataactag tttagcccct ttttctgcta atagcttcgt tgttgcttca ccgattccgc
    48721 ttgaagcgcc catgatgaca atcacttttt ctgataaatc attcattcta ttctcctcct
    48781 gttttgaaaa atctcttgct tatactcact atctcttatt tcatcttact gttcaaataa
    48841 tccgttcgac aggtttgacg attttggcag ggattcctgc aacgatggta ttgtctggga
    48901 catctttcgt aacagttgca ttcgctgcaa caatggcatt ctcgccaatc gttacgcctg
    48961 gcagaatagt tgctcctgct ccgatccaag catttttctt gatgtggatt ggctttactg
    49021 acaagcctct tcgttctttt ggatcggtta gatggttcac cgtgatgagg ttgacacgag
    49081 gaccaatcaa tactgaatct tctaaacaga tgccacctaa gtcaacgaac atcacttgac
    49141 gattgataaa gacatttttc cctatactaa tatgtttgcc gaaatctgta taaaaaggca
    49201 gcagaacagt caccgtatca tctactttgt cactaatgat attttctagc cgtttgcgga
    49261 tatctgctgg ttcatggtac ccagtattca gcgctgctaa aggctcttcg ttttcagctt
    49321 ggatctgatg gatcacttca aagagcggat ccgttactcg aatctcttta ttgacgattt
    49381 gtttttcgat gaggcttgtc attttgctcc ctccttttat ccttacttta taacggacgg
    49441 cttatcatgt ctaatactta taaaacatac ttaactattc cttttaacta tacttagtgg
    49501 tatgcttttt taaaaacagg agggaaaaaa tggatattcg tatactgacg tattttttag
    49561 cagtagctag agaaaaaaat atcagccgag cagcaaaatc tctgcatatc acgcaaccta
    49621 ctctctcaaa acaactgaaa gatttagaag aagaacttgg tgtgacactt ttcactcggg
    49681 gctcccgaga gatacagttg acggattctg gtcgatatct ttattcaaaa ggaaaagaaa
    49741 tcttgtcgtt ggtagaaaaa acggcgaaca atttaacaaa tgacgcaatc atctctggag
    49801 aaatctacat tggcggaggc gaaactaaag caatctcttt catttctgat agccttcatt
    49861 cgttgatcaa ggcgcatcct gatatccagt ttcatttata tagcgggaat gcagatgata
    49921 tcatagacaa actggatagc ggattacttg attttggact cgtaatcgaa ccgacaaaca
    49981 aacaaaaata ccagtcattt cgactgccag cccaagatcg ttggggactt ttgatacatc
    50041 gaaatcatcc tttagcaaag caaaccgtca tccatccgca ggaactgaaa actgttcctt
    50101 tgatcatttc ccggcaaacg tcagtggaca gtcaactagc tgaatggcta ggtttcagca
    50161 tagatcagtt atcgatcgtc ggaacatata acttattgta caatgcttct ttgatggtcg
    50221 ataacgggac ttttggtgca ttagctctag atgggatcat caatacttat gggacggaaa
    50281 aaatattcat cccactcgat ccgccattac aagcttcact gaatctcatt tggaaaaaag
    50341 accagcctct ttctcctgct gctcgtaaat ttttagatgt cctaacggag aaatacagtt
    50401 aagtagagtt tttttccttc gctttcagct ttttaacaac gaataagata agcaaaagat
    50461 ccaacgatta aataacataa gtttcttaat ttatttcttc cttttatttc tgataattcc
    50521 agtaaattac tataattata aaaaaagaat tgacaaaaca taactgtcta tataaaattg
    50581 attacgttaa caataattcg tttcatgtga ctagatcata ctaggcatga aaaatctctg
    50641 aggaacatgg tttccctagg aggtttttcg tgtctatttt tgtttggccg caatcaactg
    50701 gtctagcaaa cgtgaaaacc aaatcttcaa aaagggtgcg cgcatgaaaa tcaaaaagat
    50761 ctttaatcaa aatgcagtat tggtagatga cggtggacag gaaaaagtag ctattggaaa
    50821 agggattgga tttgacagaa aaagaaatga tttgattttt gatcgtgatg tcgaacggat
    50881 atttgtcatg gaaccagaag gtcaaatcaa gttgcaaaat ttacttaatc agattgatga
    50941 acgcttttta tttgcagcag aaacgatcat tgatcatgcg gaaactgttt tgatggaaaa
    51001 gttgaatgaa catgtattga tcgctttgac cgaccacatt gctttttctg cggagaacat
    51061 taataacggt atcgtcatcc gcaacaaact tttaagagaa atcgaagtgc tttacagtga
    51121 tgaattcagt attgctcaat gggcagtaga gtatctgaca aaagagcttg ggattccata
    51181 tacttatgac gaagcaggat atatcgcaat ccatattcac agcggacgaa gcggtcggaa
    51241 caataaccat cgcagtatcc gtgaagtgac gattgtatct gacatcatcc atttagtgga
    51301 atcagaattg gaaacagata tccattcaga accattttca ctgaattatt caagactggt
    51361 gaatcattta cgactgcttc tacaacgaac ccatgcgcaa caatatgctg ttttagacac
    51421 ggaaatcgta gaaatggtca aacgaaaata cccagaaagc tataagattt ctaaaaaaat
    51481 ccgtgtgttg ctgaccaaag aataccagct cgcgatcacg aaagaagaac tgggttactt
    51541 ggccatccat atcgagcgtt taagaagcgc aatcgtacaa acaaatgtta acaatcatga
    51601 ggaggaaaaa aattgaaagc atatctacaa cgaatgggac gttcccttca acttccagtt
    51661 gcggtcttac ctgctgctgc tttactagta gggatcggaa actggtgggc atcttatagt
    51721 aacgacattg tcgctcattt tttacaagct ggcggtaacg cagttttagg tcaattacct
    51781 ttgctgtttg ccgttgggtt agcactaggg atgtcagtgg acaaatcagg tgctgctgcc
    51841 ttggcaggtt tggtcgcatt tgaagttcca gtaaatgttt taaaaactga ttcagtagct
    51901 actttattga atatcaaacc agaatcagtt gatccatctt ttgctcagat cagtaacgta
    51961 tttattggta ttattgccgg attgattgcg gcagctcttt ataatcgttt ccacgaagca
    52021 aaattaccga tggctttatc tttctttagc ggcaagcgtc tagtgccaat cttggctgcc
    52081 tttgtcatgt tgctgatcag tgcagtgcta ctgctcgtat ggcctccggt ttactctgct
    52141 ttagtttctt ttgctaaatt cattttgagt ttaggctggg gtggtgcagg tctttatggc
    52201 ttcttcaacc gtttactgat ccctacagga ttgcatcaag caatgaactc cgtgttctgg
    52261 tttgacgtag caggaatcaa tgatattggt aaatttttgg cttctgaagg aacaaaaggc
    52321 gtaacaggaa tgtatcaagc tggatttttc ccaatcatga tgttcgggct tccagcagga
    52381 gcatatgcta tttacagaaa tgcacgtcca gaaaacaaag caaaaacagc ttccttgatg
    52441 ctagcagcag cttttgcttc attctttact ggtgtgacag aaccacttga attttcattt
    52501 atgttcgttg cttggccatt atatgtcttg catgcaattt tcactgggat ttctttagca
    52561 gtgagtgcat tcttccattg gacagcagga tttgccttta gtgccggatt tgtcgattac
    52621 ttcctatctt tgaaaaatcc gattgcgaat cagccattga tgttgatcgt ccaaggatta
    52681 gtaacagcag tgatttacta ctttggcttt aactttgcta tcaaaaaatt ccatctgatg
    52741 actcctggcc gcgaggaagc agatctttca gatgacgata ctgcaacgac taattcagac
    52801 aataaatatg cggcacaagc aagcaaaatc tacgctgcat taggcggagc cgacaatgta
    52861 acttcgatcg ataactgtac tacacgcctt cgtttgcaag tcaaagatac aggcctgatc
    52921 gatcaaaata aaatcaaagc cactggcgta cctggtatga agatcatcga cggaaaaaat
    52981 gcgcaagtca tcgtaggtac agaagtacaa ttcgttgcag atgagatggc aaaactacat
    53041 ggtggtgctg cagcacgacc tgcacaaaca aacaccgtgg ttaaaacaga aacatttgcc
    53101 ggtgaaacga tcgaacaaga tatttacgct atcgcaaatg ggaaactgat tccaatcact
    53161 gaagtttcag atgatgtatt cgcggaaaaa atgatgggtg acggctatgc tgtattacca
    53221 gaaaatggag aaatcttctc tccaatcgct ggtacgatca caaacatttt cccaacgaaa
    53281 catgctgtcg gaatccaaac agatgctggt atcgaagtct tgcttcatat gggcatcaac
    53341 actgttgact taaaaggcga accattcact ttatatgtag aagaaggtca aaaagtcgca
    53401 agaggtcaat tgattgcttt agttgatctt gccgctattc aatctgcagg caaaaacacg
    53461 gatatggtcg ttgtattcac aaatggcgac aaagtccaaa gcttagaaat cgaacccgca
    53521 cgtgatgtaa aagcaaatga taaaatcggc tctgtttcca acaaagcctg agccatcgtc
    53581 ttccccagac ttttttatcg ataaacaaac aggagctgag acaaaaatct tgtctcagct
    53641 cctttttccg aataaaaacg gcgttctcct gccaactccg cggtaataag tccagctaaa
    53701 cgaaacatat gaagagctat tttttatttg actcttctta ttacttgatg cagaacagct
    53761 ttttcacaaa atttttcttc atactcaaaa ctaatcggct ttttcacaac ctctttatac
    53821 attattcctg atccaatatt tcttttaatg ctgcttcaag agaagttaat ggttttccca
    53881 atactttttc taaatcatca gaggaaatag ctaactgatc ctttttaata tcatgttgga
    53941 tcgctaaaaa catgtcagct gcttcttgag ggaatccggc ttcttttaga ttttcgacaa
    54001 acgctgcatc acttgcttca ataatttcta actctttacc tgtcgcacgc tctaatgcct
    54061 tggctaattc ttcatagtca gttagattgc cggataattc taagatttct ggagagtcac
    54121 tttctactag tacttttgct gcagcttctg catattcacg tttcaatgcc caacctgttt
    54181 ttccatttcc tgcagcataa acgaattgac cagtttttaa agcctgccca atgataggta
    54241 attcattctc tacataccaa ttattccgta aaaatgtatg ggaaatacct gaatccttaa
    54301 tcattttttc agtgaattgg tgatctggcg ctaatacact gatcgagtga tcggcatctg
    54361 caaaacttgt ataagcgata taagataccc cagctgcttg tgctgccttc actacattct
    54421 tatgttcggc ttgacgattt cctggaacgc cagagacaaa aagcaatcga tctattcctt
    54481 tcaacgcttc tttcattgag tctaaatcat cataatcacc aatacgtata ttaaatccag
    54541 cttctttcag tgcttctcct ttttcttcac tacgtactag tacatagatt tcattttgtg
    54601 gaaccatctt ttttaagaat tccagcgcat aaccaccaaa acctccagtt gctcctgtta
    54661 ctaaataatg catatttgcc actccctatt ctttttattt gttaagattt acagctgtac
    54721 atttataaat tacaccttta tcataaagag tgtggtaaga taagtcaagc aaaaaaaatg
    54781 aaaggatgac aactgatgaa gtattctctg caatttagtg atgcaatcca tgtacttgcc
    54841 tatattgaaa tgtttcaaga tacccgatca ctttctagtg agatgattgc cagtagtatc
    54901 gaaacaaatg cagcaaatgt acgtaaaatc atgagtcagc tcaaaaaatc cggtttgatc
    54961 tttacaaaaa ccggaaaacc gcagccttcc cttgccaaaa gtccagatca gatttcttta
    55021 ctagatgtct atcgcagcat cgaaggtaat acacagctta tccaagtcga tccaaaaaca
    55081 aatccaaatt gcgtcgttgg tgcgaatatc caagaagctt tagaagaaag ctacgctcgg
    55141 ctgcagaaaa aggcagaaga agaaatggct aagatcacac ttgatagtct gatacataaa
    55201 atagccgttt tggaaaaaga aaaaagacca gaaaacacag gcctcgtaga gagattttta
    55261 taattctctc tactgtgcct gcatttttct gatcggaatc gtctacataa attcttttat
    55321 tctccggggg acaaaagcct tgtcatgccc ctttttcctc tctaatgctc aggtcaaagc
    55381 gctgaagtca tgacgtcttg ataaacggtg ttcaagtagc tgaccctcgg cattagttct
    55441 gaaaaatgca aaatatggaa agctatttcc catttttcct ctctaatgct caggtcaaag
    55501 cgctactttc acgacctcta tattatcatg gtttattgac taccggtatc cagatttctc
    55561 ccatatattt cccgttggta actcccattt cgactacagc atttggaccc ccaacatagg
    55621 cgtaatcttc tacttctctt aaaacatgcc caaaggccgt attcgtcaaa tcatttctta
    55681 attcttcagg cgattctgct aaagcgctta caacaagata cgttcctttt gggaatggga
    55741 tgattcgcgt agtgtttgga acatcctgac tcgtttgaac accgacatag tacatcattt
    55801 tcccgttata gggttcgttg actgtaaaga aataatgatt ttcagcagct tgtttcaatg
    55861 catctattgt tccattaccg ataacttttt gctcaaatgc ttgtttctct gcagccaaac
    55921 cgacaaaatc cgtattgcta ctcttcaatt ccacaccaat acccgtcacc gtaaaatctg
    55981 gtttttcttc gatcctatac tttgccattt ctcccaccct ttctattata ttaagttcat
    56041 cttacataaa attaaaggga aatgacacga ttacgctctt ttttctaggg atatttttat
    56101 tttttaacta tttttttgct ttcactgcaa tccaaatctc actgtaaaca ttactgaaat
    56161 cctctcccca ttttgtaaaa gagatctcgg gagcttcgac taacccataa tctgaagaag
    56221 gaagccattc tgcatagatt ttcccccaag tatcttgtaa agtttgggga aatggccctt
    56281 tattaggaaa aatggcccaa gtgtgttctt ctatagcaag catttctaaa tcagcgtacg
    56341 gattttcttt tgtcgtagca aagccaatca tgtgcatcaa actgcccttt tcttccaagc
    56401 ggtctccatc aaatccataa gaaacgttga ttacttgatt tggatataaa tctcctaact
    56461 tatgcatctc ttccctttga gtctccgtga tcgtctgcgc taacttttgt atttcttgat
    56521 tgactccttc aaatttgaca ggaacttttt tcgccacacc tgccacataa aactgttctt
    56581 tcttttcgat acgaaattcc atcgattttc ctcctctgac atcaataaaa aatgtcaagc
    56641 gtggaaaaga tttttgtatg ccgtatctac tgatttctga aggcagatat cctgaccaat
    56701 cacgaaaagc tcttgaaaaa ccttcgactg tttcatatcc atatctaaac gccgtttctg
    56761 tcactcttga tccatctaga agatcgcgat tagccaaagc caatctacgg tttttgatat
    56821 agtccattag cgacatccct gcaataaacg taaagatgcg ttttaattga tattcagaga
    56881 ttcctgtatt ttcggctatt attttatagg aaagtccttc tgtcaaatgt tcttcgatgt
    56941 aatcgatcaa ttggttcaga tctttaagca tatttatctt cctccttgat tgccttttta
    57001 tcatattatc aaagaaagtc aattacttga tgaatcagga accaatttag tcagatgtag
    57061 aaaatgttgt atggatctaa agaaaattct caagcagcgt ttcgtaacgg ataattggta
    57121 ttatctgcct atctatgttt tacctttaga aaaataaatt ttggggaaga cagattctaa
    57181 gtaaacaaag cggtaaaaat atcttttatt cccttagtta atccgcttac tacctactgt
    57241 acaaagcaaa ttgttgttca aactgctgat cagaacgctg cttggatttt tctttgcgat
    57301 acatcatacc tcttttatca attggaacaa ttatttattt ctaacaaaat cacttcattt
    57361 ttgtcagata aataaaaaac aaaaaaagtt ccatctttaa aacacgctat tcttttactt
    57421 tttctcacat tctctaagaa aagaaaagga gaatgaattt ttgacaattc gagcaaaagt
    57481 gattatcaaa tatgtaaaat cagctacttt tttcttaaac gtttctttat actaaatata
    57541 aataagtgtt tcatgaaagg agaactagat gaataattgg cttgagtatt ttcctgaaaa
    57601 cgttttggaa cgcggttaca gctatcatct gcacggtttt gtccgtcatt tgaactatac
    57661 aagcaagtac ttgtccgcaa cagtttctgg cacggaagat tataaggtag tgatcacttg
    57721 ggatgaaaag accaacatga cttgtgattg tctatatgcc atagaaggaa aaaaatgcaa
    57781 acacatggct gctgtcttat tcgcttacga agaacgtcca ataaaaaaat ccaactactc
    57841 actttccgaa ctctcgtccc ttgtttcctc cgctagttcc tctcttgtac gggagctttt
    57901 aacagagatt cttatagaac atccgcactt tatcgaacgc ttcaaagtta agatgccatt
    57961 tcatgcaata aattattcag ataaattaac aactatcatc cataaatacg atcatattat
    58021 caagaaaaac aaaaacagga aaacagcgaa gttcatcatg gagatgcgaa agttcatcca
    58081 agaagcagtt gaatcgctta ttcagcaaaa tgcctatctt cccgcattcg aattgatcaa
    58141 tgaagtgatt gctactctcg aaacattcta ttgggagcct gaggatgaac gaacccttct
    58201 tctgatagag gactgttatt atttatggaa agaattatta gcagaagcac ctcatgcaga
    58261 aaaaaggcaa atgttctctt ggttcgtctg ccaagtcgat catactgacg cctcttattc
    58321 aaaacgctac tctataaaaa tcctgaaaga agactttcgg gaaaaagaat tttctaacca
    58381 aaagaaaaaa atagataaaa aactaaagaa acggtaaaga aagacgattt caatgaaaaa
    58441 tagcaagtaa acgataacaa ccatcctaaa tccacaagaa atacagcaga ccttgcttta
    58501 aaaacacgaa tcatgcaaag gatgaagtaa agaagactta acgcgtaccc aatattagtc
    58561 atttgactat taggtacgcg ttttgtttta taagtcatga caaatttcct tcgttgctgg
    58621 atagattttc cggcattgtt gatagatttt atgatacttt tctacatttt gtaagagagg
    58681 ttccgctgca tctgtatatt ggataaaatt ctgacaacaa ctttcaggtg tgtcgaacca
    58741 ccctaaccct agtgcagcaa tcattgttgc gcctaatgca ggtccttcct ccatacttaa
    58801 acaatagacc gttgcatcga aaatatcagc ttggatttgt agccatgcaa gatttttcgc
    58861 gcctcctccc accgaaacaa tacgtgtaaa tctgcgaccc gctagttctt tacgtttcaa
    58921 tcccaccatt gacaaatgct cattaaaaat ttagaatatt cacaagttta acgacaatta
    58981 tgaaaattta tgtcgtgcta aaggagtttt gttattggat gaaaagttag atataaaaac
    59041 tgcgatcaaa gacacgttac ctaccgtttt cggttatatc ggtattggac ttgcatttgg
    59101 tatcgttggg aaagctgccg gatttcatcc actagtcgtc acgttgatgt ccctgctggt
    59161 ctatgctggt tctgcccaat ttatcacagt cagcatgctt gctagtcaca gcccattgct
    59221 ttccatcgtt ttctcgacct ttctagtcaa ttcccgaatg attctgatga gtatgacgat
    59281 tgctccttat ttcaagaaaa atcggctgct tcaaaatctg ctgattggca cattgctgac
    59341 agatgaaagt ttcgcactgg gaatgaataa attgaactat actggacaaa agttaaactt
    59401 tcgttggatg aatacagcta attggatttc ttatttgacg tgggtgggtt cttctcttgt
    59461 tggcgcactt ttagggaatt ttattactga tccgaaaaag tttggtttgg atttcgccat
    59521 cgtcgctatg tttatcgggt tactttatct tcaagtcatt tctgatagaa acacctctaa
    59581 acgattacag ttgatcctga ttggtctcac tttgattctg gtatatgtcg gactgatttt
    59641 tatcccaagc aacttagtga ttgtagttgt aacactgatt gggtgcggat tgggggtgtg
    59701 gatcaaacat gccttctttt gagtttacat tgctgactat tttaggttgt actttagcaa
    59761 cttggctttc tagggtccta ccatttgtct tactgaaaaa attcgattta ccgcaaccgt
    59821 tgcttgagta tttaagtttt gtcccgatcg tcattatgtc tgctttatgg ttcagcagtc
    59881 tatttaccca aaatatcgga catctgccgc agatcaatct cgaaaatgct ttggcttcag
    59941 ttcctacact tttagctgct attctttcaa aaagcttatt ggtgatcgtc ttggcaggaa
    60001 ttctttccct ttcgttgatt cgcttattat aaataaaaaa acaagagctt atggcaaatt
    60061 actgtcatgc gctcttgttt ttatcaaagt caaataagaa aaaaatcggc gtattcttgc
    60121 ttatccgttg aacggaccac taacaacgac ttttcctaac atatgtcctg tttctacgtc
    60181 tttggttgct tgtttcaagt tcttcgcatt catcccatct gaatagacct tgctcaatgt
    60241 actgcggata atcccttcat ttgctaaagc agcaatgtgc gctaaagctt ctccttgcgt
    60301 ttcgatttca tagttatagt ctgttttagc gaacatatac tcccagtcga agctgataga
    60361 ttggtttttc caaacaccta tatctaacgg ctctttgatc cctacgatcg ttcccacatg
    60421 tccaaatggt cggacaaggt gcttgatttg atcaaagtag cgggtaatat cgaataatac
    60481 agcgacatac tctacttgat cgattcctaa ttcacgaaaa cttttactta agtcgtgatg
    60541 ataatcgatt ggatagtcta cacctgtttt tttcagccat tcaaaattct tcggacttgc
    60601 agtcgcgtag acttctaggc cagcccaatg cgctagttga ttcaaaatcg aaccgacgcc
    60661 cccggatccg ttgatcacta agattttttt cccgcgattg gcattttctt ctggagttag
    60721 accaaatttt tcaaataaca attcataagc ggtcaatgag gtcaacggca aggctgcagc
    60781 ttcttcatct gaaagatttt ttggtgcaag agcgacaata cgttcgtcaa ctagttggta
    60841 ttcttgattg cttcctgctc ttgttgttgt acctgcgtaa aaaacgcgat cgccgacaga
    60901 aaatttttgc acttcgtcac ctacagcaac aactttcccg actccatcaa aacctaagat
    60961 acgtaaagca tttcttatcc cgttatcttg gcgaagtttc gtatcgacag gattaacaga
    61021 tactgcgttg acttttacca gaagatcccg tgaactgggt acaggtatct gttctttttc
    61081 atcaataaag ctttttggat catcgatcgg caacccttca taaaaaccga ctaccttcat
    61141 taattccttt tctgacatac gaattcctcc ttagcttcat caagttggag catccataca
    61201 gtgttcattt caatatatat agtatgctat ttgttccacc ttttttattc atcataatta
    61261 ttctcttact taaagtaaac tatttgcact tttttggtta aaaaagaggt tgcgacaaga
    61321 cttttgtcac aacctcttat aaacggtgtt ctcctaccaa ctcttcggtc acaagtcaaa
    61381 atattcatca aacatgagaa gctgtttttt gaaattgctc cttgtgactc agagttaaac
    61441 ggcaggctca caacctctga tataaacggt gttcaatcaa ctgaccctcg gtattagctc
    61501 aaaaaacgac aaaatatgaa gagctatttt tgtttggctg ttcttattac ttgatacagg
    61561 acagcttttt cacgacctct aattcacggt gttcaagcaa gaaatcattg ttcactgaaa
    61621 agcgttggat gttctttttc aaaggtctct aagatctctc gtacttcatc agtagatttc
    61681 gtattcatca actgaactcg caagtcattt gctcctggaa atcctttgat atagatttta
    61741 aagaaacgat gtagtcctgt gatggaacgc gggatgattt ctgaataatg atcttgcaga
    61801 tctagttgca gacgaagtag tccgatcagt tctttttctg tatgttccct cgggtctttt
    61861 tcaaatgcat aaggattctt gaaaatccct cggccaatca tgatgccatc aacgccatat
    61921 ttctcggcca attcttctcc tgtctggcga tcggggatat ctccattgat cgtgattagt
    61981 gtttgtggag cgatttggtc acgtaaagca atgattttag gaatgacttc ccaatgtgca
    62041 tctactttac tcatctcttt acgcgtacgc aaatggacag aaagattggc tatatcttga
    62101 tgaagtaggt gactgatcca ttcttccatc tcagacattt ccgtatagcc gatacgcgtc
    62161 ttgacgctga caggcaaacc gccagcttta gctgcttcaa tcaattgtgc cgctacttct
    62221 ggacgaagga tcaagccact gccttttcca cgttctgcta cattagggac tgggcagccc
    62281 atgttgatat cgattccttg gaagcccatt tctgccatag caatgctcat ttctctaaaa
    62341 aattctggct tgtctcccca aatatgggca accatcggct gttcatcttc tgtaaatgtt
    62401 aatcttcctc gtacactgtc ttttccatct ggatgacaga aactgtctga gtttgtaaac
    62461 tcagtaaaga agacatccgg tgctgctgca tgctttacga catggcgaaa tacaacatct
    62521 gttacatctt ccattggtgc taaaacaaaa aaaggctttg gcagctcttt ccaaaaatta
    62581 gtagtcattt atttgttact ctccattcta tcaagcagtg aagtcgcaat ctttctcaaa
    62641 aacattgtca ttatactagg aaacaaaaaa agaagcaaag tgaacagctt aaaagatgtt
    62701 tctgattgag caaaaaaaag actgtgacaa aaatcttatc acagtccatt ttccggaata
    62761 aatggtgttc aaaagcttgc atttgcggta ataagtccaa ccaaacgaaa aataggagga
    62821 gctatttttg tttggctgtt cttattactt gatgcagaac agctttttca caacctctcc
    62881 actaaacggt gttcaatcag ctgaccctcg gtattcgctc aaaaaacaac aaaatatgag
    62941 gaactatttt cccgtttgtt tctctaatac tcaggtcaaa acgctgattt cacaacctct
    63001 tttctaactt ctcaatcctc ttcctttatt gatcaaatac caagtaacgg cgtacaaaac
    63061 aacgatgaat aacacaagta cgatcatcga tgttgctact ggcacatcga tcgttccaag
    63121 gaatccgtaa cggaaaccgg agatcatata aacgatcgga ttgacttttg aaacagcttg
    63181 ccaaaagggc ggtaacatag agatggcata gaaaacgcca cctagataag ttaacggctg
    63241 caagacaaat gtaggcacga tcgatacatc atcataagac tgagcaaaaa tcccgttgag
    63301 cagtcctgct aatgaaaaca agattgccgt catcaataat gtaatgatga ccatgaacca
    63361 tgaatacaca tgaagtggta caaagaacaa ggaaatgatc gttacgagag agccgacgag
    63421 aatactgcga cccacaccac caatcacaaa gccccaaata atcacatgcg taggaacagg
    63481 tgctaccaag atttcttcga tatttttctg aaatttttga gagaagaagg acgaagaaac
    63541 attggcatac gaactagtga tagcagacat cataatcaaa ccaggaacga tgaattccat
    63601 atatgaaaaa ccacccatgt caccgatccg cccaccgatc atttttccga aaataacaaa
    63661 atacaaggat gtcgtgatca ctggcggaac cagtgtttgg acccatatac gcaaatagcg
    63721 gttcgtttcc ttgatagcta aactttttaa tgcagtaaaa taaagattaa acatttttct
    63781 cctccgtatg attattttct tctgtgattt tcaagaacag ttcttctaaa cgattcgact
    63841 tattcctcat agaaagaact ttgattcctt gtcttgtaag ctgatcgaag attccgttca
    63901 ccccttgatt tcgttcaact tcgacagcga ttgtctgctc atcttcaaat gtacaagcat
    63961 atccttcaat cacaggtttg gtatcatatg gcgctaaatc aaagataaat gtttcaaatt
    64021 gcagttttga cagaagctct ttcatacttg tattctcgat cagttcaccc gattggatga
    64081 ttccgatgtt gcgacaaagc atttcagctt cttctagata atgcgtcgtc aaaatgatcg
    64141 ttgtaccatt ttcgttcaat tctcgtagaa actcccacat ctcgcgtctc aactcgatgt
    64201 caactcctgc tgttggttca tccaagatca gcaaacgtgg ttcatgcatc aatgccctag
    64261 caatcatcag tcttcgcttc attcccccgg aaagcatacg tgcacggaca tttctctttt
    64321 cccaaagatt ggactgcttc aaatattttt cgctgcgttt catcgcttct ttgcgagaga
    64381 caccgtagta gcctgcttga ttcacgacga tttgctggac cgtttcaaaa gggttaaaat
    64441 tgaactcttg tggaaccaat ccaatctgtt gctttgctcg aactagatcc ttgtccagat
    64501 cataaccgaa gacattcact tttccagatg ttttattgac taaagaagta ataatcccga
    64561 tcgttgtaga cttcccagct ccatttggcc ctaatagcgc atagaaatct ccttctttca
    64621 ccgaaagatc gattccccgc aatgcttcga ccccacttcc atagatcttt ttcaaattat
    64681 ttatttcaag cgcatttgcc atttatttcc tatctcctta tagacatgat tcttaattgt
    64741 atcatggaat acagcagatg aaaaaacaac ttggcttcca cacaaaaaca cacctgctaa
    64801 caaagaggag atgtgttttc tagttcatga tcatcttcga tagaataact atctaaacaa
    64861 ctctggaact tttaaaatca taaaagtacc gacagcaact actacgatga catatagaag
    64921 atccttataa ctgaggttct tgtctttttt attcatgtta agctttcctc cgtcctttta
    64981 tcgaaagctt ttttctttta ttttaaccga aataaataaa atggaaatag ttattttcaa
    65041 tttctgtttt cgctgtttgt tttacggaga actttgccat ggaacgtgcg tctcgtcgct
    65101 gatgctaagt tttttcgata aaagctgcta gaaggaagac agcgtggttt attttgtatc
    65161 gtcttttgct aaatcttcca agatcatctg gacagcagac tcgttcccat tgaattctgc
    65221 cacttttttg gcatcaatgt acttcttttg ataatcgtct ttttggaccc acgcatcatg
    65281 cttcgtttga taaagttaat caaacggata ccactgacgc tgttcatcga acaacaaact
    65341 ttctttttgg gcctgttcaa ctatggattt aggataattc aaaactttca gcaaggcaat
    65401 cgcatttcgg gtccttgaag gtccttcttt taatttgaaa tcaaaactga ttccttttcc
    65461 ttctgttact tgttcttcaa agtggacatt ctcacaataa ttctttaaaa tctctgtcaa
    65521 ttcgatatca tgtgtggcga caaatgctaa agatggatac tccgcaagcc accgaacgac
    65581 tgaagcggaa gaagcaatcc gttcgatcgt atttgttcct tttaaaatct catctacgaa
    65641 gcagtagcag cgttctttgg aagccacttg gtccagcaaa cgtttgatcg atttgatttc
    65701 tgaaacaaaa taactgtcgc cttcaaataa atcatcttcg attgccatgg aagtcaacac
    65761 atgtccaggt tgcagggtaa actgttctgc aatcgctgtt tggatcgtct gtgctagaat
    65821 acagctgatg gctatacttt tgacatacgt agattttcct gatgcattgg aacccgtgac
    65881 taatgtattc ttctgccagt tgactggatt aactaccgct tcttttaaca atggatgata
    65941 gatatctttc gctgtcacac cgccctcagt aaactctggt cggcaagtga tcggcatata
    66001 ggtgcgataa ttcaaaacgg ctgctgcaac ttccaattct cccagcaatt cccacagctt
    66061 gatggcttca gttgaatgct tttctaattt agtgagaacg aaatgatagg agataaatgg
    66121 cagcatgaac atgatgttga catattcaaa aatcaattct gcttcactcc cgctcttcat
    66181 tcgaaatgaa aaacctaatt tagggatgtc tcttaatggt ttagtttgct gtttcagctc
    66241 tttttgaagt ggtgtcgtca tttttgctaa ctgattggcg gctgaaatcg ttgaaaccaa
    66301 ataactcatg ctattcagct ctgtttctag tgtttgtttc ttcactagat aatagaccgt
    66361 attgaatact aagccaccga ttgctagata gattcctagt acttgcccta aaagaagcaa
    66421 acctacaccc accagcggaa gcaagccaag aaaaataaat aaacctacgc gtccaatctt
    66481 tttacttttt ccatccgcta gatattgttt tgcaaaatta tgatcttttt ttcctaaacg
    66541 agcgaattga tattggattc tttctctcag ttgaggattt tcctgataaa aagcaattag
    66601 tttttctaac tgataatctt ctccaaaatc aaagctacgt aaacgctgat acaacgcttc
    66661 tgaacctaca ctagaatagg tactgttgat cccttcaaat acttcgaaca tatccaagtc
    66721 ataccaagta agatcgtcga tttcactatc ccatgaacgg aattttttct ccgtgagcca
    66781 cgcatccttc aaactttctt ctttatcaaa tctcggttga taaggaattt ttccccaatt
    66841 actacgaact gtttccttta ctttcaaacg tgaaaaaatg tctaaaacaa ctaataaaat
    66901 aacaactgca ataataatta aaacgataaa ttctctttgg cccatatccc tctccgttcc
    66961 ttgatttgtt agttttagta tagcactgtt gcgctatttg aaaagggggt acaaaaataa
    67021 ctgtcttcgt tacctaattc gtatcaatca caccaaaata aaaacacctt ccaaaaaaga
    67081 agatgtcttt aaaacgagat acaatttttt gtcattcact tcaggtaaat tagagccaat
    67141 taaaccctcc gcaacttgac ggagatggag aagatgcccc cgtctaatct agcggtcatc
    67201 tctcctccca ttccttccac caattttttt gacaggtaaa gcccgattcc gctagattcc
    67261 gtatttgtgc ggctggtatt ttcggtataa aaacgctgga agactttttc aacagaggtt
    67321 tgcgctcctg gtttgatagg attggccact gttaatcgaa tgaatgaatc ctcttttgaa
    67381 aatgtcacct ttgcttgtcc atctgcataa cgcaataaat tctgtatgat attttgcagc
    67441 actcgcagca acatgagcgg atctgctaat acagttgtat ttatcgagtg ttcagcgaac
    67501 gctacctcga tatttttctc agaaaattgt tcataaaaag agaaaaatac ttcttccacc
    67561 tctttagaaa aagaaagcgt atggagatcc atttcttttt gcttcgtctc tattcgagca
    67621 agatcataaa actgatccgt catactgagt aatcttgcaa cagattgttt gatgatcgtt
    67681 aaatacttct cccgtttctc cgtatcctct acctgttcca gtaattgtac ataaccgtta
    67741 atagcagtca aaggagttct gagatcatga gaaaggccga cgatcgatag tctgatgttt
    67801 tcttccattt cttgaaatgc ttgtcctttt tgttcatttt catccaccca tgtattcagt
    67861 gcatctacta ggtccattag attcttttct cgaaattcga ctgaaagacg accaccatat
    67921 tcttgtcgtt cagaaagagt ggcgattttc ttagttaatc tcttgatttc cctttgcagg
    67981 aagaaaataa aacttcccat aaagataaca acgagaagca acagccactt aatcaaatct
    68041 aaaccccact ccccacaccg tatgaatata cacagcatgt gcctttgcta gtttccctcg
    68101 aagattggaa atatgcatat tcactgtttt ctcactatca aaatatggtt cttgccaaac
    68161 tgtttcataa agatttgctc gcgaaaatac ttttttcgga tgttctaaaa aaagcttcag
    68221 cagatcgaat tctcttcctg tcaaatggac agccacacca ttcacattta catccctcga
    68281 ctctttgtcc agtaagattt ccttgtaata gatgcgttgc gacagatctt ttacttggac
    68341 agaagtctga tgacgaagtt ggatgccgat tcgtaacaac agttcttcga tatcaaatgg
    68401 tttcgtcaca tagtcatccg ctcctgctgc caacaaggaa actttatctc tttgatcgct
    68461 ttttgctgaa agaacgatga tcggaacatt cgatgtctgt cggatttctg ctaacaatgc
    68521 ttcacctgaa agccctggaa gcatgagatc tagaaggatc aaatcgacag gatatgtgct
    68581 taacaataat tttccttccg tacctgaata agcatcaaga agtttgtatc tctgttcaag
    68641 aacctcctcc agtaaagaat gaacagcttc atcgtcttcg ataatcaaaa tagtttccag
    68701 caggaacacc tacttaatgt cagatttttg gaaaataaac attcctagag ctgatgatac
    68761 cacgattgtt actagactga ccagaatcat tttcggtgct tgcgaataag ttgcttgttg
    68821 cgcaaagtcc gtatacatga gccacgtttc cgtaaaccac tccgttagaa attccaagcc
    68881 tttgattttt gcgaaaacac cgggaacgaa ggccgttccc atgatataaa gaaaagaaag
    68941 aagcaaactg acactggtac ttctagtgat gaatgtcaaa gccactggaa cagataatgt
    69001 cgctaatatc agcagaagca atacaggaaa tacttttaga acataatttc catagttttt
    69061 gattccctca acttcaccaa atccgaaagc aagtgtgtaa gcaatcatgg ctagccccgt
    69121 aatcaaaacc acgccaagtg ttgtgatcaa aagcgtaacg agaagtttcg acacataata
    69181 agtcattcga ttccgtccta aagataacgt attgcgaatc gtaccgtttt gaaattcttc
    69241 cccaatataa aagcacgcaa atgctgcgaa agccagaaga atccatgcag ccattttttc
    69301 caccattaaa atccctgttg caccgttgat gactgtatcc gttgcttggt ttaattcatt
    69361 gccgtatttt gtatgcatat accattcgtt ccaagaataa aaaagcggaa gtacgaccat
    69421 cagtcctagt gagacccaca ttttacggct cttccatact tttatttttt cagcagttaa
    69481 tagattaaac atgtggattg cctccagtta attgtaagaa ataatcttcc agtttttgcc
    69541 caactaggtg gataccatcc acaggaactt ttgcctctac caatgcttga ttgatggctg
    69601 ctacttggtc aattccttca aaaagctgga taacacggct agattggaca aaataatccc
    69661 tataaccaag agagtcgaga accgttactg cttgttccgt cgccgaagtg tcaattttta
    69721 taaattgacg agattcttgt gccaattctt ctttcgataa ttctttgatc aagtgtcctt
    69781 catgcaaaat accgtagtga gtggcgatct gtgacaattc atctagcaag tggctagaaa
    69841 gcaagacggt gatgccccgt tcttttacca aacgttggat gatttctcgc atttctgcca
    69901 tccctgctgg atccatccca ttcgtcggtt catccaaaat caaaaattct ggattcgtga
    69961 tcagtgcatt tgcaatagct aaacgctggc gcatacctaa agagaaattc tttgctttct
    70021 ttttccctgt attttccaat cgcatcattt tcagcaggtc ttcgatttct ctatccgaca
    70081 caccgccgtt cgctgcttgg atacgtaggt tatctcttgc agttaattct ggataaagag
    70141 caggggtttc aatcgattga cccatacgtc gtcttgctgc ctgcaaatcc gtcgttccaa
    70201 ataattcgat cgaaccttca tcaatcgaga tcaaacccat aatagttctc ataaaggtag
    70261 acttacccgc tccattctcc ccaatcaaac catagatcat tccacgtttg atttcgatcg
    70321 atactttatc taatgctttg gcagcaccgt attttttggt tataccagtt gctttcaaga
    70381 ccgtttcatt tccaaaatcc atacttatcc ttctttctta ttgataagtg aagtatagtt
    70441 gacgggtata aagaaagcag ccagaaatgt ataaagaaag tgtaaatttt ccaattgaat
    70501 ttcaagaaaa atcagactgt ctcgcagacg tggttgagtt gtctgccaat caaagagcgc
    70561 accaaacagt gctaatccaa gtggactggc caccatggta atcgttgtta tcgttgacat
    70621 cagacgtcct tgtatatgcg ttggaacttc tcgctgaagc cagaccatat aaaaagcaaa
    70681 agaaaacatt aatccttaaa aacggactta tgaaaaataa tacatgccgt ttgggattta
    70741 caattagcta ccaaataaga ggttatgaca aaagactttt cacaatccct tcttccgaat
    70801 aaacggtgtt ctcctgccaa ctcctcggtc acaagtcaca atatttatca aacatgagaa
    70861 gcaatttttg taaattcctt cttatttctt gaagctgacc acttctgtca caacctcaga
    70921 agcggataaa taatattgtt tgatgatact ttatcttttt cccgtttgtt tatagatcga
    70981 atgatattat agaccaagaa tcctacctat taacatagct aaaaacacaa aaaaggcact
    71041 ttccaaattg tggaaagtgc cagaaaagtt aggattaagg taactgcgct cagcattgct
    71101 tcgcccagta cgattctcgt aactcgtgaa ctcgaacgat aatcgcaatt aacgttttga
    71161 gaactgtgaa gctttacggg ctttcttaag acctggttaa acaaaactct attttattgc
    71221 attttacagg aatgtatttc atgcgaaatt aataagtctt tgtttataga gttttactag
    71281 ggtataaaaa gttgtatgtt atcattacct caaaacatta cctcagcttg gcgagttggt
    71341 tgattgaaga ataaatcatt tatctagata tctcaataaa aaatgatttc taagaaactt
    71401 gtattttcgt gttattattt ttttgcccta tcaaaatttc taattcttct agcgtaatat
    71461 gattatgaca cataatcgat tcaattactt caatacctat ttttttcgag aaagatccct
    71521 tttgttcact cacaaaaata ctttcagaag acatatataa ggaacgaagt tttggaatta
    71581 gtatatcgta caaatagacc accataaaat cgtccttgca accattctca aaaagaatta
    71641 aatttgctga ttgtgttaca tatatcactg aattacattc atggtcaatt ccaaaaacaa
    71701 tgtctacttc attttctttt ctaattcgcg cagttacatt tttcaaactt tcaccattac
    71761 ttataaatgc tttagttact gtaagctctg atgtttgttc agatattcct tttataatat
    71821 tttgttcatc agccacattc cccataaatc cgccgattcc ttttaagtaa taattctcac
    71881 ctaagagtcg cttgcattca ctgaattgat aaaaaaacca gttaaaaaaa tcttctggaa
    71941 aaataaattc tgatcgaact ttatttatat ttttagctcc tattaatttt ataactcgat
    72001 taatgttcac ttgctgcgat gaacatataa ctgaataaat tgagttgttt aattcaaaaa
    72061 aacaacttta acatatgcat cattaattcg ttatttttta ggtagatatt gatcattgtt
    72121 atctctcttt ttttgcttcc catactccaa cttagaaatt gccgttataa aatttatttt
    72181 aaaggtgact ttttcccctg aagtatcggt agtaggaata cttaatacct cagcttctga
    72241 ggaggtatcc caattatagt tatactttgc atcatcacca taaagaacaa ttccattttt
    72301 tttatcttgt gccgttagct ttactggttc gcttactttt cttgttaata tcttggactt
    72361 tacatcatcg atattgctta ttttatcaag cttaaataat ttacaaatta atttcgtact
    72421 agtttttata tttg
//
LOCUS       DACDLM010000005        67464 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.005, whole genome shotgun sequence.
ACCESSION   DACDLM010000005 DACDLM010000000
VERSION     DACDLM010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 67464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67464
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.005"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            385..951
                     /gene="amaP"
                     /locus_tag="IV356_000337"
     CDS             385..951
                     /gene="amaP"
                     /locus_tag="IV356_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAP9014064.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            964..1152
                     /locus_tag="IV356_000338"
     CDS             964..1152
                     /locus_tag="IV356_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAP9014065.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            1165..1722
                     /locus_tag="IV356_000339"
     CDS             1165..1722
                     /locus_tag="IV356_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAP9014066.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            1754..1996
                     /locus_tag="IV356_000340"
     CDS             1754..1996
                     /locus_tag="IV356_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAP9014067.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            2337..3551
                     /locus_tag="IV356_000341"
     CDS             2337..3551
                     /locus_tag="IV356_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HAP9014068.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            3582..5009
                     /locus_tag="IV356_000342"
     CDS             3582..5009
                     /locus_tag="IV356_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP9014069.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            5032..5958
                     /gene="glsA"
                     /locus_tag="IV356_000343"
     CDS             5032..5958
                     /gene="glsA"
                     /locus_tag="IV356_000343"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HAP9014070.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            6166..6555
                     /locus_tag="IV356_000344"
     CDS             6166..6555
                     /locus_tag="IV356_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014071.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFF"
     gene            6694..7626
                     /locus_tag="IV356_000345"
     CDS             6694..7626
                     /locus_tag="IV356_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014072.1"
                     /translation="MIDYVETHFFKRRYLEDEKSFIIREIEIAIGRKAFPLGLKEEDK
                     KSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEVVY
                     KNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYLLS
                     EKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFVVS
                     ESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQNGL
                     ETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            7847..9610
                     /locus_tag="IV356_000346"
     CDS             7847..9610
                     /locus_tag="IV356_000346"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HAP9014073.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            9694..10152
                     /locus_tag="IV356_000347"
     CDS             9694..10152
                     /locus_tag="IV356_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HAP9014074.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            10261..10944
                     /locus_tag="IV356_000348"
     CDS             10261..10944
                     /locus_tag="IV356_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAP9014075.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            11091..11705
                     /locus_tag="IV356_000349"
     CDS             11091..11705
                     /locus_tag="IV356_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HAP9014076.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVLALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            11721..11927
                     /locus_tag="IV356_000350"
     CDS             11721..11927
                     /locus_tag="IV356_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014077.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            12468..13598
                     /locus_tag="IV356_000351"
     CDS             12468..13598
                     /locus_tag="IV356_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAP9014078.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            13690..14445
                     /locus_tag="IV356_000352"
     CDS             13690..14445
                     /locus_tag="IV356_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAP9014079.1"
                     /translation="MKVSQKIILSILLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEP
                     KSIPTTLNVALIGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGM
                     NKINAAYSYGGVDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSL
                     DLDGVYINKGEQVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFK
                     LPKAVGKLLGSIQTNLPESVLLDCGMDFLKDIC"
     gene            14503..16542
                     /locus_tag="IV356_000353"
     CDS             14503..16542
                     /locus_tag="IV356_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HAP9014080.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSYQATRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(16651..17802)
                     /locus_tag="IV356_000354"
     CDS             complement(16651..17802)
                     /locus_tag="IV356_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAP9014081.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(17956..18486)
                     /locus_tag="IV356_000355"
     CDS             complement(17956..18486)
                     /locus_tag="IV356_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014082.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(18585..18935)
                     /locus_tag="IV356_000356"
     CDS             complement(18585..18935)
                     /locus_tag="IV356_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HAP9014083.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(19092..20621)
                     /gene="ahpF"
                     /locus_tag="IV356_000357"
     CDS             complement(19092..20621)
                     /gene="ahpF"
                     /locus_tag="IV356_000357"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HAP9014084.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(20631..21194)
                     /gene="ahpC"
                     /locus_tag="IV356_000358"
     CDS             complement(20631..21194)
                     /gene="ahpC"
                     /locus_tag="IV356_000358"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003756453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HAP9014085.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(21338..22000)
                     /locus_tag="IV356_000359"
     CDS             complement(21338..22000)
                     /locus_tag="IV356_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP9014086.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            22184..23830
                     /locus_tag="IV356_000360"
     CDS             22184..23830
                     /locus_tag="IV356_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAP9014087.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            23821..24903
                     /gene="uxuA"
                     /locus_tag="IV356_000361"
     CDS             23821..24903
                     /gene="uxuA"
                     /locus_tag="IV356_000361"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAP9014088.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(25011..26564)
                     /locus_tag="IV356_000362"
                     /pseudo
     CDS             complement(25011..26564)
                     /locus_tag="IV356_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
     gene            26712..27853
                     /locus_tag="IV356_000363"
                     /pseudo
     CDS             26712..27853
                     /locus_tag="IV356_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(27979..29058)
                     /locus_tag="IV356_000364"
     CDS             complement(27979..29058)
                     /locus_tag="IV356_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP9014089.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(29161..29601)
                     /locus_tag="IV356_000365"
     CDS             complement(29161..29601)
                     /locus_tag="IV356_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP9014090.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(29658..30068)
                     /locus_tag="IV356_000366"
     CDS             complement(29658..30068)
                     /locus_tag="IV356_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAP9014091.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(30248..30682)
                     /locus_tag="IV356_000367"
     CDS             complement(30248..30682)
                     /locus_tag="IV356_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAP9014092.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(30782..31630)
                     /locus_tag="IV356_000368"
     CDS             complement(30782..31630)
                     /locus_tag="IV356_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP9014093.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            32019..33785
                     /locus_tag="IV356_000369"
     CDS             32019..33785
                     /locus_tag="IV356_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HAP9014094.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            33887..35146
                     /locus_tag="IV356_000370"
     CDS             33887..35146
                     /locus_tag="IV356_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP9014095.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            35293..36594
                     /locus_tag="IV356_000371"
     CDS             35293..36594
                     /locus_tag="IV356_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP9014096.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            36597..37448
                     /locus_tag="IV356_000372"
     CDS             36597..37448
                     /locus_tag="IV356_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP9014097.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            37461..38276
                     /locus_tag="IV356_000373"
     CDS             37461..38276
                     /locus_tag="IV356_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HAP9014098.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            38427..39593
                     /locus_tag="IV356_000374"
     CDS             38427..39593
                     /locus_tag="IV356_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP9014099.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            39823..40470
                     /locus_tag="IV356_000375"
     CDS             39823..40470
                     /locus_tag="IV356_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HAP9014100.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            40554..41498
                     /locus_tag="IV356_000376"
     CDS             40554..41498
                     /locus_tag="IV356_000376"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HAP9014101.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            41633..43084
                     /locus_tag="IV356_000377"
     CDS             41633..43084
                     /locus_tag="IV356_000377"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HAP9014102.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            43105..43941
                     /locus_tag="IV356_000378"
     CDS             43105..43941
                     /locus_tag="IV356_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAP9014103.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            43941..44600
                     /locus_tag="IV356_000379"
     CDS             43941..44600
                     /locus_tag="IV356_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAP9014104.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            44726..45415
                     /locus_tag="IV356_000380"
     CDS             44726..45415
                     /locus_tag="IV356_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014105.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            45421..46377
                     /locus_tag="IV356_000381"
     CDS             45421..46377
                     /locus_tag="IV356_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HAP9014106.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            46421..46933
                     /locus_tag="IV356_000382"
     CDS             46421..46933
                     /locus_tag="IV356_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP9014107.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(47189..47737)
                     /locus_tag="IV356_000383"
     CDS             complement(47189..47737)
                     /locus_tag="IV356_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP9014108.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(47826..49007)
                     /locus_tag="IV356_000384"
     CDS             complement(47826..49007)
                     /locus_tag="IV356_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HAP9014109.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(49243..50751)
                     /locus_tag="IV356_000385"
     CDS             complement(49243..50751)
                     /locus_tag="IV356_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HAP9014110.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            50910..51101
                     /locus_tag="IV356_000386"
     CDS             50910..51101
                     /locus_tag="IV356_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014111.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            51304..52221
                     /locus_tag="IV356_000387"
     CDS             51304..52221
                     /locus_tag="IV356_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HAP9014112.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            52214..53287
                     /locus_tag="IV356_000388"
     CDS             52214..53287
                     /locus_tag="IV356_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014113.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            53435..53953
                     /locus_tag="IV356_000389"
     CDS             53435..53953
                     /locus_tag="IV356_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014114.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            53934..54326
                     /locus_tag="IV356_000390"
     CDS             53934..54326
                     /locus_tag="IV356_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HAP9014115.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            54402..55337
                     /locus_tag="IV356_000391"
     CDS             54402..55337
                     /locus_tag="IV356_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HAP9014116.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            55470..56249
                     /locus_tag="IV356_000392"
     CDS             55470..56249
                     /locus_tag="IV356_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HAP9014117.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            56242..56559
                     /locus_tag="IV356_000393"
     CDS             56242..56559
                     /locus_tag="IV356_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAP9014118.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            56803..58413
                     /locus_tag="IV356_000394"
     CDS             56803..58413
                     /locus_tag="IV356_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAP9014119.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            58570..59418
                     /locus_tag="IV356_000395"
     CDS             58570..59418
                     /locus_tag="IV356_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP9014120.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            59649..60128
                     /locus_tag="IV356_000396"
     CDS             59649..60128
                     /locus_tag="IV356_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014121.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            60161..62389
                     /locus_tag="IV356_000397"
     CDS             60161..62389
                     /locus_tag="IV356_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAP9014122.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            62518..64161
                     /locus_tag="IV356_000398"
     CDS             62518..64161
                     /locus_tag="IV356_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAP9014123.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(64234..64779)
                     /locus_tag="IV356_000399"
     CDS             complement(64234..64779)
                     /locus_tag="IV356_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HAP9014124.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(64802..65287)
                     /locus_tag="IV356_000400"
     CDS             complement(64802..65287)
                     /locus_tag="IV356_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP9014125.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(65277..66089)
                     /locus_tag="IV356_000401"
     CDS             complement(65277..66089)
                     /locus_tag="IV356_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HAP9014126.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(66228..67340)
                     /locus_tag="IV356_000402"
                     /pseudo
     CDS             complement(66228..67340)
                     /locus_tag="IV356_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
     gene            complement(67361..>67464)
                     /locus_tag="IV356_000403"
     CDS             complement(67361..>67464)
                     /locus_tag="IV356_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAP9014127.1"
                     /translation="LESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT        22436 a        12005 c        13194 g        19829 t
ORIGIN      
        1 tataaaccaa agaagtgaat aagaaaaatg ataatataaa aataaagtaa gaacgcatta
       61 aagtaactaa agttatttat tgtatttttt aattctccga aaaaatttaa taaataaata
      121 gaatcttgta ataataactg agcataatct ttgcaatttt taatcttgaa taatatcctt
      181 taagtatagc cagcaatcaa aagtaaatag agaataagta agcaattgtt atttcagtat
      241 cagactggca ataaaacgcc gttatgatcc agcaatgttt ggtagcgctt tatttactga
      301 tgctatgcta actgttcgct atctatactg tgattgtcgg tagagttatt tacagggtaa
      361 aaataagttt ataggaggtg gaaaatgaat aaggggttaa aaataatcgg tgttatcatg
      421 agtttactgc tactttcagt atttctagcg attgcgttga tcaatgcgcc gtatattatg
      481 cctgaacaat tggaacgatt tcgcttcttt actttaacga attactacat gcaacaatat
      541 attttctggg cagctgtagt atttgccgtt cttgctatta tcatcttgct agtcgttctt
      601 ttctatccaa agtcaagagg aactttcgtt atgaaacggg aagatggcaa actaacaatc
      661 gacaaaaaag cgatcgaagg gttggtacgt tcccatttac acgaagaaga gttcattcat
      721 tcacctaaag tacggatacg ttcaacgaaa aatcgaatcc atatccatgt caacggagac
      781 ttgaaacgaa cttcttcatt agtagggaaa acaggtgtat tgatgcaaga tatcgaagaa
      841 gaagtaacta aagtactcgg aacaaaagaa acggtcaaag tggcagtcac atacagcggt
      901 tatgaagaac aagaagatac aagagactac aagcactctc gagtggaata ggagggccaa
      961 ataatgaaag aactattttc agcatacaag ctccctatta tctttggggg tcttggacta
     1021 ctgctagctg ttttatggtt aacgattgga tttttcaaga cattgttgat cataatcatg
     1081 acagcaattg gcgcaggaat cggtttttat ttgaaacagt caggaatagt tgatcaattt
     1141 tttaaatcat aggaggaaac aaagatggaa aacaaaaaca tgaatacaac aaatggatca
     1201 gttttggcaa atgaaaaagg agaaaaccgc atgatgaatg gtgaattgac ttatgaagac
     1261 aaagtcatcc aaaaaatcat cggttatgca ttgaaagatg tagatggtct attgacatta
     1321 gatggcggat ttttctcaaa tatggctgaa aaattagtca acacagataa cgtaacagca
     1381 ggtatcaata cagaagtagg taagaaacaa gtagctgtgg atctagatgt gatcgtagaa
     1441 tacggtaaag acatcgaaga tatttacaac caaatcaaag aattgatcag tactgaagta
     1501 aacaatatga cacatttaga tgttatcgaa gtgaatgtga atgttgcaga catcaaaaca
     1561 caagaagaat accaaaaaga tcaagaaaca gtacaagaca aagtaacaga agcagcaaaa
     1621 tccacaggac aatttgcttc acgccaaaca gataaagcaa aatctgctgt aggcaaaggt
     1681 gcacaaaaag tcaaagaaaa taacgaacca cgtgtacaat aagaagtaag aagtcagtta
     1741 ggaggaattt aaaatgggat ttatttgggc attaatcgtc ggcggtatca ttggagcaat
     1801 tgcaggagca atcacgaata aaggatcatc aatggggatc atcgcaaaca tcattgctgg
     1861 tttagtaggt tcagcaattg gacaagcttt actaggaact tggggaccaa caattgcagg
     1921 aatggctatc attccatcat tgatcggtgc aatcatttta gtattagtcg tttcattctt
     1981 tgcacgtaaa ttataagcaa attgaagaaa aacttatgtt gaaatgaaga acaaatttga
     2041 gaaccgtagc gacactcgct gcggttcttt tttatatatt ttatatgaag tattctttat
     2101 tccttatgaa aaaatatctt taaaaataaa aaaagacgaa aataaacggt tttctataaa
     2161 aagaagaccg tttatttttt gtctttattt gtgtgaaaaa cgaaaaagag cacaacacat
     2221 caagctttta ttaattgtct gtcttttata aatgcaagta ttaattcaaa aaaacagaag
     2281 aaaaaaacaa ctacaccttc ttttatactc gtaatcgtag aaaggaggcg aaaaaaatga
     2341 atacattacc tatcaataca ggagatacag cattcatgat tttatgtaca gcaatggttt
     2401 gcctgatgac tcctggtcta gctttttttt acggcggatt agcacggaag aataatatac
     2461 taacgatcat gtctcaatct tttctctccg ttgggataac aacgattatg tgggtatttg
     2521 gtggattcgg attggccttt ggacgggata tcggcggtgt tattggaaac ccggcagatt
     2581 tctttttgat gagacatgtt acaagcttcc ccaacatgtt tcatggtgca acgattccat
     2641 ttttaatgtt ctttctttac caactgatgt ttatcgtgat taccgttcct ttgatgacag
     2701 gagcttttgc agggagattg aatttaaaag gctatattat acttgttatt ttttggaatc
     2761 tgctgattta tttccctgtt tgccactgga tatggggtgg cggatttttg gatcagatgg
     2821 gatttagaga tttcgctggt ggagcagtca tccacacgac agctggattc ggctctttag
     2881 catgtatcct cacacttggt caaagaaaga ttcctttagg agaaagaagt cagcatagca
     2941 gtcttatggc agctgctatc ggtacaggac tgctttggtt tggctggttc ggttttaatt
     3001 ccggtggtgc acttcgagca gatgaacaag cagtcaatgc atttggttca acattcatcg
     3061 ctcttgcatt tgcgatgatt acttggctga tcattgcaaa agtaaaagga aatggctttg
     3121 attttgtcga cgtactaaca ggatccgttg ctggattggc agccattacg ccttgtgccg
     3181 gttatgtaga agcaaaaagt gccatgctga ttgggatcat tgcgggtatc gtctgtcatg
     3241 ctgctgttga ttttcgtaaa aagaaacaat gggatgatgc acttgatgtg tggggtgttc
     3301 atggcatggg cggattcaca ggtacgattc tgatagggat ctttgcatct aacagccatt
     3361 tactaacgaa tccaagcagc tggtacttct tagggattca agtgattggt gtcatcatta
     3421 ctgccgtgta tgcctatgtg ctgacaacag tgattttaaa atcggcgatg cactttacaa
     3481 cgatcactac tacaaaagaa gaacaagaag aaggattgga ctttttcttc tttggcaaca
     3541 aactcaattg aaacaaattc aaatagaaaa gaggaagatt catgcaacaa agcaaaacga
     3601 aaattcctgc aaaaaaatta acgttctttg gctttttggc tatgaccatc tcaatggtcg
     3661 tttcattata tgaatatccc acattcgcga cctcaggctt cagcttagta tttttcttgt
     3721 tattaggcgg tttgctatgg tttatccctg tggcattgtg cgcagcagag atggcaacgg
     3781 tgaaaggatg ggaaaaaggc ggtgtctata cttgggtcag tcgcacattg ggaaaacgat
     3841 tcggttttgc cgcaatcttt ttccaatggt ttgagataac agttggctac ttgaccatgc
     3901 tgtatttctt aactggtgca ttatcctatg caacgggtat tggtgctata caaaacaata
     3961 aatatctgaa attggcaatc ctattgatta ttttctgggc tattttactc tcacagttaa
     4021 aaggaaccaa atacacttca ttgattgctc ggatcggttt tgtagctggt atcttgttgc
     4081 cagcattagt cttgtttggc ttagggatcc attatgtcgc ttcaggcgct ccactacaaa
     4141 cgatactgtc tatgaaaaca ttgattcctg atttttcgaa attgcctacg ctggttgttt
     4201 ttgtttcctt tattttagca tatatgggcg tagaaacatc tgccagtcat gcaaatgaaa
     4261 tggaaaaccc taaaaaggat tatccattag caatgtttgt attggttatt ctggcaatca
     4321 ttttagatac ttttggcgga ttgaccgtcg ctactacagt acctcaacat ggtttgtctc
     4381 ttaatacagg ggtgattcaa tcgttagaat tcctattaag acacattgat ccaaatcttg
     4441 catggattgc gaaaattctt gcgattcttg tttgtttagg tgtcatcgga gaaattgctt
     4501 cttgggtaac ctctccttca aaagcacttc acgtagcagc agaagaagga ttacttcctg
     4561 aatattttgc aaaagaaaac acacacggtg ttcctgctca tttgatgatc gcaaatggga
     4621 tcgttgcaac aatctgggca gccgtcttta cattaagcgg cggggggaat aatctttcat
     4681 ttcttgcagc gatgtcattg actgttgtaa tctacctgat gttgtacttt atgtttttcg
     4741 cgggctattt gaagctggtt tttaaagatg acagtcttga aagagcctat caggttccag
     4801 gcggaaaagt tgtaaaagta atcgttgctt gtttaggtct tttgacttca ctttttgctt
     4861 tttgtatctc atttgttcca cctgctagta tcgcagctgg acagcatggg atttatgaaa
     4921 cgattctgat tgtttcttat cttatcgtct tagttattcc atttacgatc tacgcatgcc
     4981 gtcataaatt ccagcatgca gaaaaataaa aaatgaaagc tggttattca aatggaagta
     5041 aaagaattag aacaattgat tggaaaaaat ttccactatt atcaaacagg acaagtggcg
     5101 gattacattc cagcattagc tgaagtggat cccaaacaat taggtatggc gatttatgat
     5161 ttggatacaa aacaactgat tgagggagga gacgccgatg tgcgctttgc catcgaaagc
     5221 atgtcaaaag ttcccgtatt gttattagca atcaaagaca acggaataga aaaagtcttt
     5281 caaacaatca acacggaacc aaccggtttt gccttcaatt ctatcatgaa tatggaaatc
     5341 aatcatcgca aacatccaat gaatcctttt gttaatgcag gagcgattgc aacaacctcg
     5401 ttgattgccg gtaaagatgc agatgaaaaa tttgagcgaa tcttgtcatt tatgaaagag
     5461 atctgtgatg atcctaatat cacattgaat gaagaaatct atcattctga atcaagaaca
     5521 ggtgatatca atcgctctct tgcttactat atgaaaggta atcaaatgat cgaaggagac
     5581 gtaccggaga tactcgatgc ttatttcaga caatgctccc tcaatgtcac cgctacaggc
     5641 atagcaaaat tagctgctgt gctggcaaat aaaggaattg ctccttggaa tggcaaacaa
     5701 atcattactg aagaaagtgc tacaatcgtc aaatcaatta tgacaactgc tggtttgtat
     5761 gatgaatcag gagagttttc cgtccatgtt ggtgtacctg caaaaagcgg tgtaggcggc
     5821 gggttgatgg cagctgtgcc aaatcgttac ggcataggtg tcttcagccc ggcactagat
     5881 ccatttggta acagcgcagc tggtatccaa ttgttgaaag atgtagtcaa agaactagac
     5941 gctgacatct ttgaataacc attcttgaaa gaggctgggg taaaagtcca aacggctcaa
     6001 agctacctac aatgaggctg aaattgtgag cttgtttgac ttttgtccca gtttcttttt
     6061 ttattggttt ttgaaagggc ttttctaaat aaaaaggaaa caaaaatacg atttacagat
     6121 atgattaaat aaaatcataa gaaaaactgg aggcgtgtat caggaatgct ggaaaattac
     6181 atcgagcgaa atatatttag aaaagtgtat ctgtgtgaac aattatttga attccaagaa
     6241 atagacatcg aacaaacagc tatttctcta agggtgacta caccaacgat ccttcacgat
     6301 ctagaaagtc tagccgagtg tctagaatat tgtataaaag aacaagtaag agagaagcat
     6361 aagtataaac tcgtattcaa acatggtatt gctctttctg agctcacaca gtttctgtac
     6421 ggtcaatctt attttttaaa gtttttaagt tattatttta atggtatatt cacgagtaca
     6481 gaactggctg atcttgaatt tatttctttg agtaaagtat atacaatcaa aaaaatcgta
     6541 ttggattttt tttaagaaaa tgattatttg aaaaataaag aaatcattat cccagaattt
     6601 gactcgcgga acatcttgct agctttagta cgttatgtca attgggaagg ctatgaaaat
     6661 aaaaatccgt atgtagaaga agcttgtaac gagttgattg attatgtaga gactcatttt
     6721 tttaaaagaa gatatttgga agatgaaaag tcctttatca tacgagaaat agagatcgca
     6781 atcggaagaa aggcatttcc ccttggactg aaagaagaag ataagaaaag cgcagaaacg
     6841 aagccgttat ttcaattagt ctgtcaagga ttggaagagc aaaaaggaat tctagactta
     6901 caagaagaag atgtctatta tattttttct ttgttcaaca gtagaaatta taccaatgag
     6961 aacatggagc tgttaagaaa agatttcgaa gttgtttata aaaattttgt tctcaatgac
     7021 ctatcactga atgaattgat tttacagatt attagtatcg ctgaaatcga cgatgcagaa
     7081 aattttattt tcaagcaatc ctttttacaa tttgtccgta cgttgtgggc agatggacaa
     7141 gtatttttac cggaaaggat ctatcttcta tcagaaaaag aacaacttct gtacggaaaa
     7201 attgtagaaa tattggaaga gtggaaaaag aaaaatcaaa tccaactaag atggaatgaa
     7261 aatttcattc gaaaattcgt caaaagtctt tctttgatca acagtgaaca agcggggaga
     7321 caggaaatag aaatttttgt tgtttcagaa agttcagtca aacaattttt ttatcgaacc
     7381 caatttcatt tgtatgcgga agaaggcatc gctgaaataa atcctatttt atttcgttca
     7441 ttagaagaat tgcctgatga atgtctatgt gcgaaaaaaa gagtggtttt gtgcgatgct
     7501 gctagctatc aaaatggatt agaaactgaa aagacaaaga tctatccaat ctcattaaaa
     7561 ggtgcaaaca tccatttgta tcatattgct caggaacttc acctattaaa aaaacatatt
     7621 tcttgatgag accttaatta ggagaccttc tacaaagctt tttaattgtc tgtagaaggt
     7681 ttttatttga gtcctgattc gtgcgaagat ctacttatat aacaagcttt ctctgaaatt
     7741 tttttaaaat gctattgact tagagtcaac tctaagtagt agaatagata aagtgtaaca
     7801 aatctatttt cattaaaaga agatagtacg gaggagagaa tgtattatga gtacagtatt
     7861 acatgtattg gatgcaatca atagccccgc agatgtcaaa aaattatctg ttgaggaaat
     7921 gaaacagttg gcagaagaga tgcgccaaaa aatcttgcaa aaggacagcg atgtaggtgg
     7981 gcacgttggt ccgaatctag gtgtagtaga attaacgatt gcgtttcatt atgtatttga
     8041 ttcaccaaag gataaaatcg tttgggatgt ttcccatcag tcttatggtc ataagctttt
     8101 aactggtcga aaaaatggtt ttgaaaaagg acattaccgt gaagtgagcg gatattccaa
     8161 ccaacatgaa agtaaacatg actattttac agtggggcac acatctacat ctatcagctt
     8221 agcaacaggt ttagctaaag cgagagatct gaagaaagaa tcaggaaatg tggtagcatt
     8281 tatcggtgac ggctccctaa gtggtggctt agcttttgaa ggattgaaca atggtggtgt
     8341 tttacaatcc aatctaatcg tattagtaaa cgataatgag atgtctattg atgagaatca
     8401 tggcagttta tataaaaact tagctgagct tcgtcaaacc aacggtaaaa gcagcaataa
     8461 cctatttaaa gcaatgggat ttgattatcg ttacgtggat aatggaaacg atctggaaac
     8521 ggtgatccgt ttatttgaag aagtaaaaga tattgatcat ccgattgtac ttcacgtcca
     8581 tacggaaaaa ggtcgcggtt atcagccggc aatcgataat aaaatgaaat atcattggca
     8641 tgtaccattt gatctgtcca ccggggaggc aaagcaagta acttctggag aaacatttaa
     8701 tatgatcatc atggattatt tggataagaa aatgcaaaca agtacagctc ctattgccgc
     8761 agtcaatgca gcgataccag gcgcctttgg actgaaaaca ttccaagaaa aacatccaga
     8821 tcattatttt gacgtgggga tcgctgaaca gcactctatc actttcgctt ctgctttggc
     8881 ttctcaggga gtacgtccag tcgtcttcca atcaagtact ttcttgcaac gggcatatga
     8941 tcaattatca catgatttag cgatcaacga gaatccagtg attattttag tcggtggcgg
     9001 aacgatctca gctagtgacc gaacacacca aggaacattt gacattcctt acttatcaag
     9061 tatcccgaac atcaaatatc ttgctccagc aacaaaagag gatatgatct ctatgctaga
     9121 ttgggcgttc gaacaaacag cgcagcctgt agcaatccga attcctacac atggtgtaga
     9181 acatggtaca gctatcgcaa atgattatag tattccagcc tatcaaacag taaataatgg
     9241 aggaaaagta gcaattttag ctttaggcgg ttttcttgaa ttaggaaaag aaacagtaaa
     9301 agcttttaga aaaaaaggaa tcgaagcaac gttgatcaat ccaggaacga tcacagaaaa
     9361 tgacgtagaa acattagata aattaaaaga aacacacgaa ttagtcatca cattagaaga
     9421 tggtagtttg tcaggaggat ttggcgaaaa tatcagtcgt tattatggtg attcttcaat
     9481 gaacgtatta aattttggtg cagagaaaga attcacggat agcgttcctg tagggcagct
     9541 ttatgaacgt tatcatttaa caccaaaaca aatcgttgaa gatagtctgc gtgtcttgaa
     9601 tattcaataa ttcattatgc tcaccatcca gataattgtt tatactagta tctggatggt
     9661 tttttcatta taaaaagcaa aggggtggat gttatgtatc agcaagtaga agaatatgtc
     9721 aaaaagttcc aagaaaaata tcctagttat caatcagaaa aattaggttt cttttcattt
     9781 ggggatacag aaaaaatggc agacgagttg agcgaactag ttgtaaaaaa gataaagact
     9841 ggtacatcaa gtggttacga tctgtataaa caagagaatg agcctttacc aaaagttggt
     9901 caattagacg tggtcctgaa tggaaaaaat gaaccagttt gtatcatcaa aaatataaat
     9961 gtgaccatct tgccttttag tgaagtcacg aaagagcatg cttggaaaga aggagaaggg
    10021 gatcggacat tagcttattg gcggaaagtc catgctgagt tttttaaaca tgcttataaa
    10081 gaagcgttga acatagaatt tacagaagag aagctggtcg tatacgaaga atttgaagta
    10141 attttctttt agtaagaaag gtctgctgaa agaaatagct cattattgtc tcctgaatag
    10201 aaaagggtta catttttata tgaagctgta tttttatata acattactgg aggagatatt
    10261 gtggatacac tggaacaaat caaaggcgga gtcgtcgttt cttgtcaagc tttggaaaac
    10321 gagccgctac acagttcttt tattatgggg agaatggctt tggctgcaaa agaaggcgga
    10381 gcagttggta ttcgagcaaa tacgacagaa gatatcaatg aaatcaagcg aatcgttgat
    10441 ttaccggtaa tagggattat caaaagagat tacgatgggt cagaagtgtt tattactgcg
    10501 acagaaaaag aagtggaaga acttttggag acgcaagcag aaatcattgc actggatgca
    10561 acttctcgta aacgtccgac agaaaaaaca actgctgaac ttgtccaaat gattcacgaa
    10621 cacggtcggt tagctatggc agatatttcg acttttgagg aagcgcttca agcgcaagaa
    10681 gatggttttg atcttttgtc tacgacttta gcaggctata cagaatattc acgaaagacg
    10741 cagacacctg attttgattt attgaatcaa atcatagaac aagtcgatat cccagtaatt
    10801 atggaaggac atactgactc tcctgaacaa gtagagaaag catatgaatt aggtgctttt
    10861 tcagtcgtag ttggatctat tatcacccgt ccgcaattga tcactaaaag atatgtcgaa
    10921 gccgcaagta aagcaaataa ctaaaaaaca cgcacggcac agattcttga caaaaaagaa
    10981 aaattgatag atagtttaaa gcagattcta agaagatgaa aaaagcatta cttttcattt
    11041 tgtcttcaag atctgctttt taacgaattt tatagaaaga aggcgaaacc atgtttgaac
    11101 ggagtccttc agaattgaca gaacgtgaaa attacaagtt gctgattggt tcagtcatcc
    11161 ctagaccagt agcagtagta acgactaaat cagcaaaaga tatagtgaat atcgcaccct
    11221 tcagttactt caatatcgtc agttcgaatc gacccatctt atccttggcg atccagagaa
    11281 aacaagatgc agtaaaagac acagcaaaga atattcttga gacaagagaa gctgttatcc
    11341 atatccttga tgaggacaac gtagaagaag taaataaaac agcagccaat ctgcctaatg
    11401 aggaaagcga actgtacctg actgacttga ctttaactga ttcagtaatc atttcagtac
    11461 tagcattgac agaagcaaaa gttcgttttg aaacatcctt atatgaacat gtcgagatac
    11521 ggaataaaaa taaagtaaca gctgatttat ttttgctaga agtacagaaa tatcatttaa
    11581 atgaaacagt ctatgatgat aagacaggaa ggatcgatcc aagaaaattg aatgctgtaa
    11641 gccgtttggc aggaaatgat tatgcagcaa taggagaaat tttcacgatt gcacgtcccg
    11701 aataaaaagg agcactagtt atgttaaaaa taagctataa accatcgaca gattcaaaag
    11761 aaatgaaaaa agaatatgaa acagtgaatg attttctgca agggcagtac ttagaagttc
    11821 cgccattgca agaccatttt gtcgttacta ctgttacttt agatggtaag gaaatagaaa
    11881 tgccagatca aacgattagc ggattgttta attactttaa caaataaata tttattccga
    11941 aaagtgaaaa aacatataaa aaaacacata aaactaaaaa attatcaaag aatcctggtg
    12001 caactgaaag aatttgcaac gggattcttt caacttattt gttatttttt tctaaaaaat
    12061 attaaagatt gttaaatttc actatttcat ttcaaattcc attgcctaat cattaggaaa
    12121 agtctatcat gaactcgtaa atagaatata gtaataacct tgttaggtga ggctcctata
    12181 caaacatagg ctgttgccca gaaacgtcga aagtcgccaa tgggtaaaac agaaactgtt
    12241 ggattaaggc tttttccaat agctaagaat gttttcttta cgttgtatag tgctaaaact
    12301 cggacgatga gatgatgcta ggtcagaatt cttgttcgaa aaggtttctg accttttctt
    12361 tatatttttg tgactgactt atttgatgag acaaactcgc tcctcacctg acaagtggat
    12421 tgctgtgtga ggaggagatg cggtgaaaaa agatcgattg gtggattttg ggtccttatt
    12481 tgactttgtc catgatcggt cttttagaag tatacagtgc cagttcttat cgtttattgc
    12541 aagccgatga aaatacaaaa agtctattat tgcgtcaact aattttcata tttttgagtt
    12601 ggagcgtgat cttcttagct cgttcagtca aactacacta tttacttcac cctaaaatag
    12661 caggatacgg tttagcctta tcgattttct ttttagtatt agtaagaata gggatattcg
    12721 gtgtcactgt caacggcgca caacgttgga tctctctgtt tggcattcaa ttccagcctt
    12781 ctgaactggc aaatcttttt ttgatttttt atttaagctg gttttttcgt gacggaaata
    12841 gtagcccaaa agatctaaaa aaaccattcc tgattacagt aggtataact tttctgattt
    12901 tatttcagcc aaagattgct ggagcattga tgatcctttc gattgcgtgg gtcatatttt
    12961 gggcagcggc ggttccattt aaaaaaggga tctatctaat cgttactttt tctgcattgc
    13021 tgattggagc agcaggcggg gtattatatt taggaaataa aggttggctt ccacagatgt
    13081 ttaatcatgc ttatgaaagg atcgcgactt taagagattc ttttatcgat agtcatggtg
    13141 cgggctatca aatgacccat tcgttttatg cactatataa tggtggcata tttgggcggg
    13201 gattaggaaa tagtatcaca aaaaaagggt atcttccaga gacagaaaca gattttattt
    13261 tttcgattat tacagaagag cttgggctaa tcggtgcatt gtgtgtgctt ttcttattgt
    13321 tctcattatg catgagaatc ttttgtttaa gcagtcgctg taaaaatcag caagctggat
    13381 tgtttctttt aggattcgga actttgctat tcgttcagac gataatgaac gtgggaagta
    13441 tcgcggggct gatgccaatg actggtgtgc cattgccatt tgttagctac ggaggaacaa
    13501 gttatctgat cctttcttta ggaatcggaa tcacgttgaa tatttcttca aagatacagg
    13561 ccgaagagtt ggcgctctat cgacctgaaa aacaataaag agaaactgag aaactctcag
    13621 tttgaattat cataaagtac aatcttttat ttttcaagcg agaggttctt ttagaaagag
    13681 gaattcgcaa tgaaagtatc tcaaaaaatc atattatcta ttttgttact gcttacatta
    13741 gtagttggct atttttcgat tgagtttatc catggatttt cgtctgcaaa acagagttca
    13801 actgtgaaaa aggtagagcc gaaaagtatc cctaccacac taaatgtggc tttgattggt
    13861 tcagatgctc gttcgaaaga cgaaaacggt cgctcggatt cacttctggt tgcacaatac
    13921 aaccagaaaa cacaacaagc aaaactgatc tctatcatga gagattcata tgtcgatatt
    13981 ccaggttacg gaatgaataa gataaatgca gcttactctt atgggggagt tgatttatta
    14041 aatcaaacat taaaggaaaa tttcaaattt gaagctccct attatgcaag tatcacattt
    14101 caagatttta tcgattgcgt taatgaactg tttcctggtg gagtcaagat cgatgcagaa
    14161 aaatctctag atttagatgg cgtatatata aacaaaggag agcaagtgat ggatggtaat
    14221 actttactcc agtatgctcg atttcgggaa gacaaagaag gagacttcgg gaggatcaga
    14281 aggcagcagc aagtgatcaa agctatctct cagcagctga aagacgtaac ttcaatattc
    14341 aagctaccca aagcggttgg gaaattactt ggtagtatcc aaacgaacct tccagaaagt
    14401 gtgcttctgg attgtggtat ggatttcctc aaagacatat gttagaataa acaggtataa
    14461 atagtgaaat aaaggaatga caagcaagag aaggaggaaa aaatgaaaag aagtgacaag
    14521 cacggcaaaa atcgaacagg cgcttatatt gccggcgcag tgatcttaat agcagctgcg
    14581 ggtggcggtt atttttacta ccagcactat caagaaaccc aagcagtaga agctggagaa
    14641 aagacagttg agcaatttgt ccaagctttg aacaagggag attataacaa agctgcagaa
    14701 atgacatcaa aaaaggcggc aaataaaagt gcattatctg aaaaagagat cttagataaa
    14761 taccagaata tatacggtgc tgctgatgtc aaaggacttc agatatcgaa tctaaaagta
    14821 gataaaaaag acgattctac ttacagtttt tcatataaag caaagatgaa tacctcatta
    14881 ggtgaattga aagatctttc ttataaagga acattagaca gaaatgatgg tcaaaccacg
    14941 atcaactggc aacccaactt ggtttttcca gaaatggaag gaaatgacaa agtaagcctg
    15001 accacacaag aagcagcaag agggaatatt atagatcgaa atggtgaacc attagcaaca
    15061 acaggcaaac taaaacaatt aggagtcgtt ccaagtaaac ttggagatgg aggcgaaaaa
    15121 acagccaata tcaaagcgat tgcttcctcc ttcgacttaa cagaagatgc tatcaatcag
    15181 gcgatttcac aaagctgggt acaacccgat tactttgtcc cattgaaaat cattgatgga
    15241 gcaacgccag aacttccagc tggagctacc attcaagaag tagacggcag atattatcct
    15301 ttgggtgaag cagctgctca gctgattggt tacgtgggag atatcacagc agaagatatt
    15361 gataagaatc cagaattaag cagtaatgga aaaatcggtc gctcaggttt ggagatggct
    15421 tttgataagg atcttcgtgg gacaacaggt gggaaattaa gcattacaga tgcagacggt
    15481 gtagagaaaa aagttctgat cgaacatgaa gttcaaaatg gcaaagatat caaattgaca
    15541 atcgatgcga aggcacaaaa aacagctttt gacagtctag gaggaaaagc tggatcaact
    15601 gttgcgacaa cgccaaaaac cggtgatctt cttgcgcttg ctagctctcc aagctatgat
    15661 ccaaacaaaa tgacaaacgg gatctcacaa gaagattaca aagcttatga agaaaatcct
    15721 gaacatccat tcatcagccg atttgcgaca ggttatgctc ctggatctac gtttaaaatg
    15781 attacagcag caatcggtct cgacaacggc actatcgatc caaatgaagt gttgacgatc
    15841 aacgggctta aatggcaaaa agacagttct tggggatctt atcaagcaac gcgtgtcagt
    15901 agtgatgtat cacaagtaga cttaaaaact gctttgatct attccgataa tatatatgcg
    15961 gcacaagaaa cgttgaaaat gggtgagaaa aaatttcgta caggcttaga taaattcatt
    16021 tttggtgaag accttgattt gccaattagt atgaatccag cacaaatttc taatgaagat
    16081 agctttaact cagatatctt gctagctgat actggatatg gacagggcga acttctaatt
    16141 actcctatcc agcaagcagc aatgtattct gtttttacca acaatggcac acttgtctat
    16201 cctaaattga ttgcagataa agagacaaaa gataagaaga atgtcatcag cgaaacagca
    16261 gtacaaacga tcgtgccaga tctgagagaa gttgtgcaag atgtaaatgg tacagcacat
    16321 tctctttctg ctttagggat tccgttggca gcgaaaactg gtacagcgga aatcaaagaa
    16381 aaacaggatg taaaggggca agagaacagt ttcttgtttg ctttcaatct tgataaccaa
    16441 ggttatatga tggtcagcat gttggaaaat aaagaagatg atgattcagc aaccaaacga
    16501 gcatcggaac tattgcaata cctcaaccaa aattatcaat aaaaaattgc tttttaagta
    16561 cagtaaaagg actgtggcgt tatcgtcaca gtcctttttt caaataaacg gttttcacga
    16621 tgtctctttc acaacttctt tttgatttac tcacacttca taaacttttt ttgtaaaata
    16681 tttgagaaca agtggagaaa taagtgtact taataaaatc acgataacta aaggtgaata
    16741 gtactgtggt tcgatcaatt gactttgctg tccaatttgt aaaatgatca aagccatttc
    16801 tccacgcgaa atcataccag caccgaccat caatgaacta tgttgagaaa aaccggcaat
    16861 ctgagcacca aaataacctc caagcaattt ggtcaaaatc gctacaagcg tcaatataga
    16921 aataaagagt agttgttcac taaagtcaga aaaatcaact tctaatccta cactgacaaa
    16981 aaatactggt ataaatactg catatcctaa agcctctaca ttgtggtata cttcttcttt
    17041 aacctttgtc tgactgacag ctatcccagc aaaaaaagca ccaatgacag agctaagccc
    17101 aacaagatcc gctacgtaag acattcctaa acaaataact agcgatacga tgataataga
    17161 agaatttgcg tacacttttt ctgcaaatga aagtaggaaa ggcgcaatcc atttgactaa
    17221 taagaaaata aaaacaaaat aaattagctg ttcaatcaaa acaagcggta aagaagcatt
    17281 gctagaagct tcccccgtta gaaaagatag gctgaaactt agaactaaaa cgactaaaat
    17341 gtcatctacc acagaagcac ccaaaattgt tgatccttct tttgtattca ctacgtttag
    17401 ttcttttaat acttctactg aaatactgac agaagttgcc gcaagaataa tcccaaagaa
    17461 aatcgcttca tttcccgaaa cttggaatgc tttgcctgtc aaccagccaa aaacaaccgg
    17521 gaagatgatc ccaagcaaag caacgaacat accaggtcgg aaatattttt tcaaaagaga
    17581 taaatcactt tccagaccag ctaaaaacat taataagatc acaccaatct ccgaaaagtc
    17641 atggactaga atatcaggtt tgacccaatt caatccagct tggcctagca aaacaccaac
    17701 aagtaattgt ccaatcactg ctgggatacc taatctccgc gagatatgtg agccaatcgt
    17761 tgttgaaatc aatatcaggc ataaaatacc aataaattcc attctcatca ttcctttgta
    17821 taaaatatag cccgaactta gcataacata cattattgaa aaaataggaa aatatactca
    17881 caaaaaaacc aacaatccaa aagatttttt tggattgttg gtttttatac ggtctatttt
    17941 aataactaaa aatgattaac gtatagtcat ttttcttatt ctgatgaaat tgataatctc
    18001 ctggatgccc atgaaaatca aaataaagcc gaatatttgg aatagaagca tcaaactttt
    18061 gaatggattg aacaataaga cgaatccgcc aatcaacaac agaatactac tataaacact
    18121 ccaactttta gcttttgtat tcatgctgaa gaacaactgg aacaagctgt tgatgataac
    18181 agctaatcca agaagaatcg gcaggataga aacgattgca ggtgcaaaag catagacgat
    18241 cagagctaag atcaggaaaa aaagaccact gaacagaccg atactccaag aacctgtttt
    18301 ccttttaaaa cggtaagcct caaaaagatt caacaaccca agcaaaacaa gataggcggt
    18361 gatcagataa ccgataaaat gaaaaacagc agaagggttt agcacaatcg caatcccaga
    18421 aataatataa acagcagctc ttaataaggc gtatttttga atattttgtt taatcgtctc
    18481 aaacatataa gaaaacctcc tttgacttat tttaacgtga actagtcatt ttaccaaatt
    18541 aaatgttaca aaatgagcga aggagaagaa tatctctgga aaaatcaact tctgaggatc
    18601 ttttccattt ttttgccttt tgctagctca tcgatcattt tatctaaata acgaatttct
    18661 ttcatcaagt tatcctcgat gtcttctact cgtacaccac aaacaacacc tgtaatcaag
    18721 gaacgtgaag gattggggac aggggcttcc gcaaaaaatt gttcgaaagt cacttgtttt
    18781 tgtagttgat attctagttc tgtttgggaa taacccgtca gccaacaaat gatttcatct
    18841 acttcctctt ttatacgatc ttttctctcc gcttttgcta catacatagg ataaacgctt
    18901 gcaaaacttg tcgtaaaaat acgattttgc gccataatca gtcacctttc tttttttcaa
    18961 attatttact acttatagta tataagaaaa agagaagaaa aagcgattat tcaaaaaaac
    19021 aaaaaggatt gtgacaaaat tcttgtcacc atcctttttt ccgctctctg actttttaca
    19081 atcttcatag ctcaagtgcg catcagataa tcgaatgctc ctaaagctgc agtagctcct
    19141 gaacccattg aaacaatgat ttgtttgtat ggactatctg tacaatcacc agctgcgaaa
    19201 acgccgggga tattcgttgc gccatttttc tcggtcacta tttcatttct tggattcatt
    19261 tcgatcgttc catctagcca atccgtatta gggagtaagc cgactagaat gaatactcct
    19321 gaaacagcta gtgtatgcat ctccatcgta cggcgatcga tataggagag agattctacc
    19381 tgattcgtac cgctgatttc tttcgtcgct gcatgtttga taacagtgac attcgcaaga
    19441 gagactagtt tatcctgtaa gatttgatct gcttttaatt ctggtaagaa ttctagaaca
    19501 tatacatgtt ttgctaaccc agccaaatcg attgctgctt caacaccaga attaccacca
    19561 ccgataacag caatctcttt tcctttaaat aaagggccgt cacagtgtgg gcaataagca
    19621 attcctttat ttttaaactc tttttcgcct ggtacattga tagaacgcca gtgcgcacct
    19681 gtcgcgatga tggcggtttt tgctttaagt gatataccgt tagctaagcc aatattaata
    19741 aaatgttgct ctttatttaa ggaaacggcc tgttgattca tcataatgtc gatagggtaa
    19801 ctacgcacat gactttctac ttgctgcatc aattttggac cttctgtgta agaggtacca
    19861 atcatatttt caatccctag tgtttcaacg acttgtccgc cgaaagaatc agcgacaagt
    19921 cctgtacgga ttcctttacg tgctgcatag atagctgcac tactagctgc tggtccaccg
    19981 ccaatcacta atacatcata aggttctttt tcaaacaact cttcttcaat caaagggcca
    20041 gtgatttttt caacaatttg ttcgatcgtc atgcgtccgc tactaaattc ttctccattt
    20101 aaaaacacag ttggcactgc catgattttt ttatcatcga tttctttttg gaacatccca
    20161 ccttcaatca tcgtatgagt aatatttgga tttaatacag ctaatatatt caatgcctgt
    20221 acaacgtcgg ggcaattatg acaagtcaag ctaacataac tgtcaaaatg caatgtttgt
    20281 gttatttttt tgattttaag actcaaagat tcactgattt tcggtgcccg tccactaatt
    20341 tgtaacatag ccagtaaaaa agaggaaaat tcatgaccga gggggatacc agcaaaaacg
    20401 attccacttt ctttgccaac tggattgata gaaaaactag gtgtgcgcat cgaatctctt
    20461 ttttcccaag agattttagg agacatttct gctatttcct tcgtaaattc agctagtttt
    20521 tgactatttt cactattatc caaactaaca gaaaaaacaa taggagattc aatcagtgct
    20581 aaatattgtt cgagattttg tttagtttct ttgtctaaca tatccaccac ctaaatcttt
    20641 ccaacaagat caaaacttgg tttcaatgtt tcgccacttt ctttccattt tgccggacaa
    20701 acttcacctg ggtgggtacg tacatattga gcagcgcgaa tcttatcaat cagtgcacta
    20761 gcgtcacgac cgattccatc tgcattgatt tccatagctt gaacgattcc gtctggatca
    20821 ataataaatg ttcctcgctg agctaatcct tgctcttcat ccaaaacatc aaaaatacga
    20881 gaaatctgat gagacggatc accgatcatc acgtattcga ttttaccgat agcatctgat
    20941 gtatcatgcc atgctttgtg agtaaagtgg gtatcggtag agcaagaaaa gacttcaaca
    21001 cctaaagatt tcaatgtact gtattgttct tgtaagtctt ctaattcagt aggacaaaca
    21061 aaagtaaaat cagctggata gaagcaaaga atactccagt tccccataag atctttttca
    21121 ctgacttcta aaaattctcc ttgatgataa gcatgtgcat taaattcttc gatttttttc
    21181 ccaatcaatg acatagtaaa acctccaata ataattattt atttataatt attgtaattt
    21241 agttggagtt gcaaagtcaa tggatatttt gttatttaat aaagattact caaaaacgaa
    21301 ggttaattat aaaaatagaa gaggtcgcaa gaaaatgcta ctgctggaaa tactcgggat
    21361 aacgttgagt aacagtttcc tgttctttca gcatcatgtg taagtgcaat cccgtttgaa
    21421 atcgagcttc ttctggtttt ttatcaacta aagccttgag taaatcataa tgttgttcca
    21481 tgatcgtttc ccatggaagc ccctgaatgg tcactcgtaa ccagcggaaa cgttctaaat
    21541 gggtattatg gtcatctaac cagttccaaa cttcttttct tcctgcaatt tcgaaacaag
    21601 cttcatgaaa taaattatct gcacggaaaa aagcgcgttc gtcatttatt ttgactgctt
    21661 tttcttgttc ttctaaaatc gtttctagca ctattcgtgt ttgtgtgtcc aatttggaac
    21721 aacattcaat catgatttgc tcttccaact gttctcggac aaagcgagca ttttctgcag
    21781 aaacaagatt aattttggaa acatacgtac cactttgagg tatcgtatac acgagttctt
    21841 gctgacgtag ttgaatcaat gcttcgcgaa tgggagtccg gccgatagca agatgttcct
    21901 ccagtgcctt ttcagatatt ttccttccag gttctaagtc agcatagata atttgtttac
    21961 gaatcgcttg ataagcttgt gattgcaagc tgcttttcat ctttattcct ccaaaatcat
    22021 ttctatgaac gtagtataac agaagaggtc tgaaaaacaa tctggtatgt cacattaact
    22081 agtaaatttg tataaatagt aaaattttgg ttgacatagc gatttttatt gcataaaatt
    22141 cacttgaata caaaaactaa tatgttagtt taggagggga aaaatgattg atttaaacaa
    22201 ctggaggaac tttatccctg aattatctca aaaagaagta gaaatacctc attttgaccg
    22261 tgcatcatta agagaaaatg gacaaaaaaa tcctgtctgg atccatttcg gtggcggaaa
    22321 tctttatcga ggatttcatg cagaaatcgc tcaacgttta gcggatctag gcgaattgtc
    22381 cactggtgtc attgtttgtg aaacattcga tgaagaaata attgaaaggg cttaccaaga
    22441 ttttgatgat ttgattcttg aagtggtcat gccaagcagt ggagagttcg tcaaacgtat
    22501 attagctgcg acagctgaca gtctgtattg tcatccagat tgttctgaac actttgataa
    22561 gatgattcga cactttgaaa atcctagttt acaattagtt acttttgcta ttactgaaaa
    22621 aggttatcga ttgaaagata caaataataa atatatagga ccgattgcag tcgatataaa
    22681 aaatggtcca aagaagccat cacatacaat gagtattctt gctgtgctac tttataaacg
    22741 ttttttatct ggagcttggc cgattgcact tgtctctaca gataattttt cacaaaacgg
    22801 tagtcaatta cgtacttctt tgctaacgat cgcaaaagaa tggcaaaagg aaggttatgt
    22861 acaaaataca tttatccaat acttatcgaa tgaagaaatt gttgcgtttc catggacgat
    22921 gattgatcgt atcaccccga atccttcctt gtcagttagc aaaatgttgg caaaagaggg
    22981 cttttcaaat atgtcgattt tccaaaccgc aaaaggaaat aatattgctc catttgtcaa
    23041 tacagaggac atccattatt taatcatgga agatcatttt cccaatggac gtccgaaatt
    23101 cgaaaaagct ggggtattct tgactgatcg tgcaacggta gataaagcag atacgatgaa
    23161 ggtgacgact tgccttaatc ctttgcatac gtctttagct attatgggtt gtttactggg
    23221 gtataggagc atagctgagg agatgaaaga tccagattta tcgctgctag tttctgaaat
    23281 cgggtacaat gaaggcctcc cagttgtgga gtctccaggt atcattgatc caaagatctt
    23341 tctggaagaa gtaattactg tgcgcttttc taatccaaat attcctaata tgcctcagcg
    23401 aatcgccacg gatacctctc aaaaggtggc gattcgttat ggtgagacga ttaaaaaata
    23461 tatggaaata gaagttaaag acccgcagac acttgtattc ataccattga ctctcgctgc
    23521 ttggcttcga taccttattg gcattgatga tcaaggaaaa ccattcatcc cgagtccaga
    23581 cccactattg acagaccttc agcataagct ttccgatatt caactgggta cgcaagatac
    23641 atcacatatt catgagaaaa tggctcctat tttgtcaaat aaagaaattt ttggtgtaga
    23701 tctttaccaa gcagagcttg gcagaaaaat agaagaaatg ttcatcaaga tggtagcagg
    23761 accaaatgcc gtacgaaaaa cattacagga ttacttacaa gaacatggag gaaatttatc
    23821 atggaaatga cttttagatg gtacggatca caggaagaaa agattacctt agatgaaatc
    23881 agacagattc ctgcggtcaa agggattgta ggcacattga tggatatacc agtaggagag
    23941 gtatggccta gggagaggat caaagaacta aaagaagaaa ttgagtctcg tgggttaaca
    24001 ctaaaagtaa ttgaaagcgt caatgtgcat gatgccatta aaattggatt accttcccgt
    24061 gagcagtata tcgaaaacta taagcagaca atccgaaact tggcagaata tggaatagaa
    24121 gtcatctgct ataattttat gcctgtattt gactgggtga aatctgacct tgactaccgc
    24181 ttagaagacg gctcatccac gttagctttt atatctgatg atattccaga tgatccaaga
    24241 gaaatcgtcg cgcgcatcga acattccagc aatgaatttg gattgccggg atgggaacct
    24301 gagcgcttag ctcctatcaa atccttgctt gaagcctatg catcagtaga cgaagaaaaa
    24361 cttcgagaaa attttgccta ttttctccaa tcaatcatcc caacatgtga agaggtaggg
    24421 gtcaaaatgg ctgtacatcc agatgatccg ccatactcga tttttggatt agctcgaatc
    24481 gtaaagaatc gagaagattt agattggttg tgtcgcatag tagacagccc ttataacgga
    24541 atcactcttt gtacagggag tattgcagaa gatccagaaa atgatgtata tgggatttta
    24601 gcagaatttt gccaaagaga tcgaatccca tttgcacatg ttcgaaatat taaattttta
    24661 gctaatcgag atttctatga ggcaccacat aaatccgaat acggttcatt agacatgtac
    24721 cgcatactaa aaacaatgta tgacaacgga tttaacggat acatccgtcc tgatcatgga
    24781 agaatgatct ggaatgagac aggaagacca ggatacggct tatatgatcg agcattaggt
    24841 gctgtttatc taaatggatt atgggaagca atcgaaaaag gaaacaaaag taaagataat
    24901 tagtgaaaaa aactgtaatt ttattatgta aataagaagg atgttcaaat tcttgataca
    24961 taaatccgga ggttgttaat aagcattcgg atttatgtat cttatttggt ctaggaagta
    25021 acttgatttt cttttttcga ttgatccatg agtgcttctt cttttaattc aaagatatat
    25081 tctgagatcc tcataatcac ttttttccag tcttctggtg tgatgattcc ttttaaaata
    25141 tagatttttt tgatatgaga aggcaattgt ttcaaagggc agtcgctgat aacgatgttg
    25201 cagttctcca taaaatcatt ttgtattttg atcgattcat ttgaaaaaat ttgttctatc
    25261 ttaacgatca gatctttact gatataaaaa tcacgcgtat agttcacacc aatcacaatt
    25321 cgcggctgtt ttttgtagcg atcatacaaa tgtactaggt cttcaaccat ccattgcaca
    25381 ttttcctttt ctaaaataac tggtaacaag tgttgatttt gttctctgaa atccatataa
    25441 aattgttcaa tggcggtttg gacttctttc aatacgctat gttcttgata aagcatgaaa
    25501 gtaggaaggg gcgtatttgg ttgattgaag ttaagaaatc cattataaag tttatttcgt
    25561 gcgaatgcca atgagtaaag aatcttttct ttttcaggta taaacaaatc aaatacagta
    25621 caaagggact ccaccatttc tcttgaataa agaacatgag gaacgtttgc tttttttaaa
    25681 agtttgtatt gctccaagct tgtttcttcc gattcgattt tcgtgataga aagtcgagct
    25741 aaaatattca ctaagatgcg ttgttcgcga caaattggca gattaggtcg caaaatatct
    25801 acagagagat caataaaaaa gtcaatatat tcatactctg tgaattcttt ttgtacgtct
    25861 ttcacagaag ttgcaggaaa attctcttta catattttta atagaaaata taatttatct
    25921 atcataccgc tatttagtcg gtcaagtact tcttttttaa aaaaagtatt catcataaaa
    25981 gccactactt gcggatcttc atcataaaat tctgtagcag tacttgaaaa gatgttccaa
    26041 taaatatcta atgctgcata ttgaatttgt acctcttttc cagaaaaaga ctttctgcca
    26101 ttattagaaa aggagataga caaaccgtac tatgctaaaa atgcattaat ctttttcatt
    26161 ttcgtataca aataagaggc actatagttt gtttgctgac tgaaactgat aatcgaattt
    26221 gtctgacagc tgaacaaaga agtcaagatc tgataactga ctgattcgtt gcagtatctt
    26281 ccaaatagac gataatagca gtaagccgga tcaattcctt caaaattcaa ctttaaaaaa
    26341 ggtttttgct tatcaatatg cagttctgtt agattgagac gctcaaagtc ttgttctaat
    26401 tctttgatgt atagtaaaaa atttgattca gacatatgga aatgatctgc taaatattgt
    26461 gtagtaataa agaaacgatg ttcagatagg aaaagaaaaa tatctaattt tgtattgctt
    26521 tttttcttca agataaacgt tttaatcgct tcttgagttt gcatgaaaga ggctcctttt
    26581 tacttaaatt gttaaaactt gaaaatatta ctgttttttt cataaattta gacaaaaaaa
    26641 cagtaaacat ataggtagaa tctctactat cttatttctt gcatacaaaa aaatcaagga
    26701 gtgagagagt tatgagatat tcaaccatct taatatcaac atttgcagcc ttaagcttat
    26761 cgcttactat aaatcagaca gtccacacag aggagacaga aacagccaaa tggacagaaa
    26821 ccaagtgggc caacgtcaat cgaattacct ttcaggatga attttcatcc ttcaattcag
    26881 gagtcgcaaa attaagaaaa ggacaaacag cgaccatcaa agcaaaaatt gactattcgg
    26941 gagacttagc acctatacta caatcagctg ttacatttga gaatgttgat cccactttgt
    27001 cgattggcta tgacgagaac actttgacta tccaacacaa gcaagcgata tttaccttca
    27061 ccgttacatt aaatcaggac ttgttaaaac cagcgctttt tactgtcaag gtatcagatg
    27121 gactaccgaa cgatcatcat ttaacgccgt atagtcagcg gcagacaatt gagcaagatt
    27181 cagccatcga ctcaggagga gatcttgttg aagaaccaac agataaacca gaaaatgaaa
    27241 ataagccaga agtaccgcct acagaaaatc cagacggaga acagaaaccg gaaatagaac
    27301 ctggagaaga acccgataca gaaactcaac cagagccaga caataaatca aaacctgaaa
    27361 taacccctgg agaaaaacca gatgtaactc cagaaccaga tacggattct ggaaaccaaa
    27421 cagtaccgga aacaaatcca gacacagata atgaaactga aaatccagaa aaaccagagg
    27481 tagatccaga agaaaaacca gatgtgactc cagaaccaga tacggacgca agagaccaag
    27541 gaataccaga aaaaataaac aaaaaaacaa ttcaagagga tggaaaaaaa gagagtaaaa
    27601 aatcaaatct agcaattcta aaaataaatg aagagcagct gaataaaaaa tcacgaatat
    27661 ttgatagcgc ccaatcagct gaaaccttaa aaagtagcaa ggatacaacc tttgctgtcc
    27721 tgaaacgaaa aataaacagc taccaaaatc cggagagtca caaaacaaag ttatactgtg
    27781 gagcggaatc attctattaa gtatagcaac aatgctttct gcaaaaagat ttaaacaaaa
    27841 cagatctctc taacatttga ataatgtctg tgaacgcatt tttcaaataa aaagaaatat
    27901 ccagaaaatg accccaaaat accagattga aatctgatat ttggggtcgt tcatacttta
    27961 tctttcttca tatttatttt aagggatatc tgtttctttt ggaagatggt tcgggatctt
    28021 tttcactttc aatacatcta aaaagaaggt aaagatcgga atgccgacaa tcaagcccca
    28081 aacgccaaag aaccgttcgc taacaagtaa gaccacaaat gtataaaaaa tcggcagttc
    28141 tgttttgctg gacatcaact tcggattcag cacataagac tcaattagat ggacaatcaa
    28201 aatcgtaatc aggatataaa caacatctcg gatgcctcct tgggaataag ctatgaaaga
    28261 tagaggaata caagaaatga taacacctgc tactgggatc agacttaaaa tgaaaatcat
    28321 gatcgctaaa ctcagcagct gatgaaagcc aaatacagcc aaggcgattg tagtgagcaa
    28381 cgtatttaaa agagcgacaa caaattgagc ttctaatacc aaaccaaatg tattgacaaa
    28441 cttatcggca aaatagtaaa tatcttgaaa gaaccaagaa aattcacttt ttaaaaacaa
    28501 tcttgagaat acaattgttt ttttcttttc aatcataaaa aagaaactta agatgaatga
    28561 catagcaaac gccactgcca tttttcctat atcctgtaaa tagccaagcg caatcgaagc
    28621 gccattttga agctgttcaa aaaaatcgtt tcgctcaata taagtatgga tatattgtaa
    28681 aacaggatct gcatcttttg gctgatgctc gtaaaaatta ataacggact ggatcatgtc
    28741 aaatgtttga tgaataagca tcgggatata ctttgtgaat gccagataga taaggtaaac
    28801 gatcagtgta taaatcatga tagctaaaac acctgtaggg attcggacaa atcgctgaat
    28861 gatttgaaca agatgaatca tcaaataagt aaagataaat gtgagcaaaa tggttgtaat
    28921 catacttcta actaagaaaa gaacaaaaac gacaaataat aaaacagtga gacggcgtat
    28981 tttttcattc gccaaaaaac gctgataaac ggtcaaatcg acaacctcca aataacaaaa
    29041 aataaacacg ttattcatta tatgatggaa tatgaaaata agaaagagca aaaagaaaaa
    29101 ccgctaaatg acgttatctt atgagttggt tttcctcata aaatcgttca tctagcagtt
    29161 tcagcccttt ttctggtctt gatgaaaatt atctagcatt tttcgggtca gatgttgcag
    29221 tgtatccaat tcttcctgtt caagtggaag ataagacttg atcttttgtg gaataccttc
    29281 tgcttgtttt tgcaacgcag caccttgagc agtcagcgta acatttacga ttctttcatc
    29341 acccgtttca cgctgacgat taatataatt tttttctgct aactttttta gtaagggagt
    29401 cagcgtacca gaatccagac acaaatcatt tcctagctct ttcactgaag tctttttctt
    29461 ttcccataaa actaacatca caagatactg ggtataggta agattcagcg gcttgaggag
    29521 gggagtgtag tgtctaatga tttctttaga ggcggcatat aaaggaaaac atacttgatt
    29581 aactaaatat agatcttcca tttttccacc tccgctgttt tactatagtg tatcatagcg
    29641 gatttacaca aaaaagtcta ttcactaact gctttcagag taacttctat atttccagct
    29701 gtagcttttg aatacggaca cactttatgc gctgcctcta ataattcttg cgtttcttcc
    29761 agagaaagac cttcgataga tccttcaatc tctacaccta agacaaagct cgtttcactt
    29821 tctgaataaa gggaaacttg tgcactgaca gtagaagccc cagagatatt tttttgctgt
    29881 ttgatcaatt ctaatgcact gttaaaacat gcactgaaac cagctgcaaa caattgttca
    29941 gggttggttg cattttcgac gcgtttacca ggagctgcaa tattcaattc gaatgtacga
    30001 tcgggattat gcacttctcc agagcgtccg cctgtgttga tcattttcgt agaatacatt
    30061 tttttcataa aattaccacc tttaattata ttttatacaa ttgaatttta cacaatataa
    30121 ttgtggaaag caaagaaatg gattggcata agataaataa gagaaagcac atgaaacaga
    30181 cgcgctttct cgaatagcaa acatatacaa aaaatatcag agacaaaaaa taatctcatc
    30241 ataaacatta catatatttc tcaaaaagtt gttttctttc ttcaaaaatt acttcacgat
    30301 ggacctgatg aagcatccat aaataaccaa aaggatctct gaacattgag ttagtcacac
    30361 caaagtccat catttctgtc atttcttgaa tctctacaca gccatttcgt aatgctttat
    30421 tatgtgtgtc ctcgatatca gagacgatga tattgaacca gatcgtattt ggatgttcag
    30481 cagtaggagc agtcaaacca agagacgtgt tttcatccag catatggaat ctcgtaccat
    30541 acaaggtaaa aatgacttca ttattgcctc tagggtaatc tgttgcctca atcagttgta
    30601 tttcatcaaa gattgtttga tacagttcta gtgctttcaa actatcattt aatacaaaat
    30661 cgatttccgt tcctttatgc ataaagatct cctctccttt tcagtcgaac agttactaga
    30721 ttcttttatt ataccagcta aagaaaacgc attcaaaaaa atagcggatt tacttaccaa
    30781 ctcattcgat tggatgataa gtaaatccgc gtcccattac ttctgctacg ctgctgacaa
    30841 tgacaaaggc acttggatcg atttcttcta tcaatggttt cattcgggaa aattcatgat
    30901 cagtcacaac gatcaataaa acctcttttg actttcgatt atacccgcct tttgcctcta
    30961 gcagggtaag gccacgtcca atctcagcac ttaagcgaag gcggatgtct tccaaataat
    31021 gttcactcat gaccataaca gatttctttc gattgatacc tgtttcgata taagtcatga
    31081 caattgaagt gattgcaata gataaaatag cataaagaaa ctcttctatt ccaaaaataa
    31141 acagattaag agaaacaacg aatgcgtctg taaaaaataa gccaatcgaa gtattcaagt
    31201 ggaaatattt tttaaaaatg aggggaggga tcgtcgtacc gccgctagaa gagttgtttt
    31261 tatataaaat cgcaactcct aaagcaaaaa tcgcacttcc aaaaatgaca gacaacaacc
    31321 gatctgaagt aatcattgtt tctggaacta ttgcaatgat taaaggaaaa accaagcttc
    31381 cgaaaagtac tttaaaaaag ggttttttac ctaaaaatag aagagctagt accaacataa
    31441 cgatattcaa cactaaaata actatagctc ggtcaaagcc taaagcagct tccagtaata
    31501 ttcctagacc gctgacacct ccagcagcaa tatgatgagg ccctaaaaac atattgatag
    31561 cgactcctaa tatgaagagg gcaaaaataa tcttaatgta tgtccatata aattgtctcg
    31621 tttctttcat ttattcactt ccttaattca ttaataatac tcttatctta ttataactta
    31681 cttttcacct taagttaact ttaattaata aaaaaattag gctagtctaa attattatgt
    31741 ttcattcttc tagaatatac ttctacgcca aaaactgtta aaaaactttt actttagaaa
    31801 attggagaaa ttgatcgctt aagataaatt caggacacta aatagtacag gaagtagact
    31861 aaaactttta aaagttttaa gtctatctat ttggcaagtt taaaaaataa aaattcggta
    31921 tcaaaaaact gttaccgata acatttttga aagcgttgtc ttttgcttct ctatcactta
    31981 tagtgatgac gtcatattaa aacacaagga ggaaatcaat ggatacagct gcaatttatc
    32041 atcgaccgga aagtgaatat gcatttctat atacgaatac aagatttcgt attcggcttc
    32101 gtactaggaa aaatgatatc aaaaaagtat atgtgctatg tggagatcca tataccataa
    32161 caactgaaaa atggtatcaa aaacaacgac caatgaaaaa atgtctaagt accaatgttc
    32221 atgattattg ggaaattgaa gtgacgagcg aaacaagtcg cttacagtat gcgttccatg
    32281 ttgttgggga agataacacg gactgttttt acggtgatca aggaattttt ccttatcgag
    32341 aaaatgtgat tactgaacca aatttttatt ttcgaatacc ttattttcat caaatcgatc
    32401 gattcactat tccagaatgg gtaaaagaaa cagtatggta tcaaattttt cccgaaagat
    32461 ttgcaaacgg ggacaaagca aatgaccccg aacacacttt accttgggga agtaaagatc
    32521 cagaccgaga agactttttc gggggagatt tgcaaggtgt gatggatcat ttggattact
    32581 tgacggacct tggcatcaat ggcatctatt tttgtcccat atttaaagcc acatccaatc
    32641 ataaatacga tacgattgat tattatgagg tggatcccgc ttttggcgat aaaaaacttt
    32701 taaaaaactt gattgatgaa gcacataaaa gagggatacg tatcatgttc gatgctgtat
    32761 tcaatcatat gggtgtccat tcaccacagt ggcaagacgt tctcaaaaac ggagaaaaat
    32821 cgatctataa agactggttc cacatccgtt ttttcccagt agattcttat cagatgactg
    32881 acttaccaga aactgctgaa aatatcccat atgatacttt tgcttttact ccattcatgc
    32941 cgaaactaaa tacagcaaat ccagaagtgc aaaaatattt gctggatatc gcaacttatt
    33001 ggataaaaga attcgatatt gatggatggc gtcttgatgt tgctaatgaa gtcgatcatc
    33061 atttttggaa aaaattcaga gaagcagtta cagaaatcaa accagacatc tatatccttg
    33121 gagagatttg gcattcctct caagcttggc tgcaagggga tgaattccat gcagtgatga
    33181 attatgcatt tacagattcg attaaagatt attttgcaaa aaagaaaatc acagcttcac
    33241 aaatggtcag tggaatgaat catcagcaaa tgctttacag agatcaggtg aacgaaggaa
    33301 cattcaactt attagattct catgatactg ccaggatctt gaccctttgc caaggtaaca
    33361 aagaattgat gaagtctgtg atggccttta tgtttcttca aaaagggtct ccttgtatct
    33421 attacgggac agaaataggg atgactggtg aagatgaccc ggattgccgc aaatgtatga
    33481 tatgggagaa ggaggaacaa gatctagagc tattcggttt tataaaagaa cttgtttctc
    33541 taaggaaaca gttgtctaag attatttctg aaggttctac tcagtggcta atagtaaatg
    33601 atcgtgaaga taagctctat ttcacacgga aactagaggg acagatcatc tatgtttact
    33661 ttaatcagtc aaaagaacct tgggtagtag aacaggaaaa tgaggtgatt cttagtcaaa
    33721 attgtcagtt gttagaagac gggaaagcag agatacgaca atacggattt ttgatcatgt
    33781 gttgaaaact gttaccggta acaacaagaa agcgtttgca aatgaagatt tgtgcccatt
    33841 ataataaggg tgtaacagca cgttgaatac aaaggaggaa atgaagatga aaaaaagaag
    33901 tgtgaaacag ttgggtttag ggttaatctc tttaggaatc ttaggcggat tagcggcttg
    33961 tggcaatggt aactcttcag cagaagggga agccgatgaa ggaaaaacgt taacagtttc
    34021 cgttgattct ggatataaag attatataaa cgaaataaaa aacactttcg aaaaagaaaa
    34081 cgatgtgaaa atcaagctag tagaaaagga catgttcgat cagttggaat cattagcgtt
    34141 agatgggcct gctggaaagg gacctgacgt tatgatggca gcatatgacc ggatcggtgc
    34201 gttaggacag caaggacatc tggcggaagt aaaactggga aatgaagcag cttacgatga
    34261 aacagacaaa gcccaagtga cttatgatgg aaaaatctac ggagaacctg cagtaatcga
    34321 gacccttgtt ttgtactata acaaagattt agtcgataca gcaccatcaa cgtttaaaga
    34381 tttggagaat ctatccaaag acagtcgttt tgcttttgag tcagaagcag gaaaaaatac
    34441 aggattttta gctaaatgga ctgactttta ttattcctat ggtttaattg caggttacgg
    34501 tggctatgta tttggtgatg atggcacaaa tccttcagat atcggtttga ataatgcagg
    34561 tgctgtagaa ggaatctctt atgcaacaga ttggttcaaa aatgtttggc caaagggaat
    34621 gcaagacata aaaagtgcag gagacttcgc cagccagcaa ttcatgtcca ataaaactgc
    34681 agcaatcatt gacggtccat ggcaagcgca aacatacaaa gaaaacaata tcaattatgg
    34741 tgtagccaaa attcctactc taaataatgg acagccttat caaccgtttg gcggaggaaa
    34801 aggatgggta gtcagcaatt atgctaaaaa caaagacctc tctcaaaaat ggcttgatta
    34861 tgtaacgaat caggaaaatc aagaaaaatt ctttgaaatg gtaaatgaaa tccctgcaaa
    34921 ccaacaagct agggaaacag caaaggctaa aaacgatgaa ttaacaacag ctgtgattga
    34981 acaatatgaa acagctcaag cgatgccaaa catcccagaa atgggcgaag tttggacagg
    35041 tgcagaaaac ttgatgttcg atgcagcatc aggttcaaaa acaccaaaag aatccgcaga
    35101 tgaagcagta aaaacaatca gtgaagccat agaacaaaaa tactgattaa aatgataacc
    35161 gtccattttt ataaaaaatg gaacaggtgc ttcagataaa agtggcaaga gcgagatgga
    35221 aaattatctt gctcttgttg ccattatctt aaaagcagtt tgcggtttag caagtttaga
    35281 gggggcattc agatgcagca agataaaaca agcaatatca acgaaaaaaa aatcacgctt
    35341 tgttcactta ttccagggat ggggcagttt gtaaatggcc aagcttttaa aggtatcgtt
    35401 tttttcgcca tattcgtcct attcattggt cagatgcttc tgggcggatt tcatgcattg
    35461 gtaggattgg ttactttggg aagtatacca atggaagatc attcattatt tattttgatt
    35521 gaaggcactt tgcaattcat cattacaatc attttcttga ttttttacgg tttgaatctt
    35581 ttagacgctt atcgagtagc gaagatgcgt caagagggca aaaaaatcaa tcggacgatg
    35641 aaggaagtca tacataatat aggtgatgaa ggttttcctt atctattgac acttcccgct
    35701 tatcttctca tgatttttac gatcattttc ccagtcctag ttacattgtt cactgcattt
    35761 actaattatg acttcaatca tattccacca gccagtttaa ttgattgggt aggggctaaa
    35821 aactttttta gtatcttctt tttaagctca tatcgtaata ctttttttgc agtcttttcg
    35881 tggaccgtga tttggacttt atgtgcaaca actttgcaaa tcacccttgg tattctcaca
    35941 gcggttgttg ctcaccagaa atttattaaa ttcaaacgta ttttcggtat cattttctta
    36001 ttaccatggg cggtcccagc ttttattact atcatgagtt tttcgaatat attcaacgat
    36061 agcgtaggtg ccatcaatac tcaagtgatt cctttcataa accagcttcc ttttgtagat
    36121 atcagtgcaa tctcttggaa aacggacccg aactggacga aagtagcaat tatcttagtg
    36181 cagggctggt taggatttcc ctatatctat gtgatggtta caggaatctt acaatcgatt
    36241 tcagaagact tatatgaagc agcaaaaatc gacggagcaa atgcatggca gcgcttttca
    36301 aacatcacgc ttcctgctgt cttcctagtg gcagcgccaa catttattac acagtatacg
    36361 gggaatttca ataatttctc catgatctat ctgtttaaca atggcggtcc cggaagcgta
    36421 ggcggaggag ctggttctac tgatattctt atttcctgga tctataaact tacgactgga
    36481 acttctccgc agtattctat ggcttcagca atcacgttga ttatctccgt catcgttatc
    36541 tgtgtgtcat tgctggtatt taaaaagaca aatgcgttca atatggggga ttaacaatga
    36601 aaaaatttca ttcgagtgct cgattccaaa aacgactttc tcactttttt acttactttt
    36661 ttcttttaat actgtcagtc attatcatct atccgctttt gatcacagca agtactgcct
    36721 tcaagtcagg aaatattgca gcttttagtt tagatctttc aagtgactgg actttaggaa
    36781 actttactcg gctattcagt gaaacacttt acgggacttg gtataaaaat acattgatca
    36841 tttctgtcct aacaatgatc gtacaagtga ctgtagtaac tttggcgggc tatacttata
    36901 gtcgctatcg ttttatcggc cgcaaatcaa gtttgatgtt ctttttagtg attcagatgg
    36961 taccgactat ggcagcattg actgcctttt atgtcatggc tttcttatta gaagcgctcg
    37021 ataagtactg gttcttgaca atgatctata taggcggtgg aattccaatg aatacttggc
    37081 tgatgaaagg atactttgac actgtaccaa tagatttaga tgaatctgct aaacttgatg
    37141 gggcagggca tttcaggatt tttttccaga ttgtattacc gcttgtcaaa ccgatgctcg
    37201 ccgttcaagc attatgggct tttatgggac cttttgggga tttcatgtta gctaagttcc
    37261 tgcttcgaac acctgaaaat cagactgttg ctgtcggctt acaaacattt atttctgatg
    37321 tgacaaacca aagagtctct ctttttgctg ctggggcaat tttgattgca ctaccgattt
    37381 gtctattatt cttcttttta caaaagaact ttgttaccgg cctgacatct ggcggaacaa
    37441 aaggatagga gcagagtatc atgcaaacat ttccgttaaa ctatttttcc gcattacgta
    37501 cgccaactca agtgtttgcg ggacgcaaac tattatcatg gcctaaattt ttcttgatat
    37561 ttgtattttt agtttccttg atggtcatgc ctgtgactct tttttatgcc aatcagatcc
    37621 aagcgattcc attagaacaa tttctatccg ttcattcgct gatcgatgaa caaggaaccc
    37681 aaaaattttc tgaacttgaa ttatctgaaa ctgggttaca agcatcgcaa caaacgatag
    37741 ctgtgacccc tgaaattttg gtaggtgtgt ctttatctga gaaacaacaa tccgatcatg
    37801 gaacttttat tgattttgag aaggaacaat gggtgatcca acaaaaggat aaatctggta
    37861 tacgccgcta tacgatgaat tatagcccat ctttccaacc agattctgta cgtacgcccg
    37921 aagatttcca acgattttta gaaagagaat tttatgccag taatcgtcca acaatcattt
    37981 tatcttatag tttaagtctt ggtcttgtcc tatttgtcat gacgagtctc attttattcg
    38041 gggcttcctt tttcttgtgg atgacaagaa aaagccaact ttcatccatt catacattca
    38101 aagagagtgc aaatttgatg ctgaatgtta tgggaatagg ttccatggca gcagcagttg
    38161 tagggtttat ccactttgac tttatcttga tgctaagtgt ccaaacaacg ataactgtct
    38221 tgctgctttt atgggttttt gtcaaaacaa gattcaaaga taagcgtgtc gaatgacaag
    38281 tttaagcgat ttatgcgaca atgaatgtga aaaaaatgaa aaataaagta gtttttgaaa
    38341 aatttctgaa aaaattaaac ttcttagttg attcttttct tttttagtat taacgtaata
    38401 gggtagtttt tttaaggagg aaaatcatgt tagagaaaac tttatacaat caattatttt
    38461 cacgttcttt ctcgctccct gtcgaagtaa attattggga cggtacaacg aaacaatacg
    38521 gagatacgga cactcctccc caaatcaaaa tcaatatcca tgaagaaatc ccaatgaaag
    38581 agattacaag taacgcatct ttggcactag gagaagccta tatggatcat cgaatcgaga
    38641 tcgagggaag tatccaagca ttgatcaacg atgcttatca gcaagcaaac agctttttac
    38701 gaggaaaaga ttatctaaaa tggctgccaa agaaagaaaa acatacgaaa caaaaaaaca
    38761 aagaagatat ccatgcgcat tatgacttag gtaacgactt ttataaactt tggctagatc
    38821 caactttgac ttattcttgt gcttatttca atacacctga agatacgttg gaacaagcac
    38881 aaatcaataa agtccatcat atcttagaca aactctttat caaagaaggc gaaacgttgc
    38941 ttgatatcgg ttgtggctgg ggaacattga tgttcactgc taccaaagag tataatgtca
    39001 aggcaactgg gatcacacta agtgaagaac aatacgattt gattaccaaa agaataaaag
    39061 aagaacattt agaagataaa tgccgtgtat tattaatgga ttaccgcgaa ctaaaaggcg
    39121 aaacgtttga tcatatcaca agtgtaggta tgttcgaaca tgtaggttct gaaaatcttg
    39181 aaggttattt caaagtggta aaagatttat tgaaaccaaa aggaacagct ttgatccatg
    39241 gaatcagccg acaacaaggc ggtgcgacaa atgcttggat caataaatat attttccctg
    39301 gcggttatgt ccctggtgtt actgaattag ttgataatat tacaaaaaac gatttgcaac
    39361 tgattgattt ggaaagctta cgtcgtgact accaattgac attagaacat tggacaaaga
    39421 attttcatca agtccaagat caagtcacga aagaaatggg tgattccttc tatcgaatgt
    39481 gggatctata tttacaagct tgtgcagctt catttgaatc aagtaatatc gatgtgattc
    39541 aatatttgct tgttcaacct ggaaacaatg acatcccaat gcatcgtgca taattgaggc
    39601 aaaagtactg tttaaagact atttaaaaag aagctaagtt ttatgatgct ccagaagtga
    39661 acttttttgt ctaacttcta ggattgtctc taaagcttag tttctttttc tttatatttt
    39721 cataataaaa gtttggttct ttaattttta aacatgacag aaaatttttt cttcgttata
    39781 cttgtaatag aatactattt tataacaaag gggatcgaat caatgaaaaa aactgttatt
    39841 tatactagtt tatttgcagc tttgttttta gctgcttgtc aatcaaatac caatcaaggc
    39901 acatctggga atacgtcttc cagtagcgaa cagcgctctt cacaggtatc ggactcctca
    39961 acaaaagcaa gcacatcttc gtctagccag acaaaaagtt ctagtgaagc aagtactcag
    40021 tcagatatca aagtgtctgc agctcgtgcg atcgaattgt tccaagataa atacccagat
    40081 actgcaatta ctagtttgga attagatagt gattggggat cttacttcta caagatagaa
    40141 ggtgtcgatg atcaaaaaga atacgaagca agaattgatg ctcaaaatga aaaaatggag
    40201 acagagaatc cagaaactct agatcgagat gaacaaaatg gtcaaaagaa aaaagaagat
    40261 ggtctggatg ttgataaatt gatcacgatt gaggaagcag caaaaatcgc cgtcgacaaa
    40321 gtaggaagcg gtacggcaac agattgggat ttggataaag atttaggtac tacttattgg
    40381 gaagtcaaag taaaagacgg caatcaaagt acatcagtca agatcaatag ccaaacaggc
    40441 gaagtactgt caactgaaca agatgattaa gaatttcttc ggaaaacaag agttgatttt
    40501 tcttttagtc atgatacact agacaaaata acttgtttga aggagcgatt tacttgagtt
    40561 tagaaacgac ctttgccaat catatctttg ccaatccttt gatgaatgca tctggtgtcc
    40621 actgcatgac tacccaggaa ttagatgaac tggctcattc agaagcagga gcatttatca
    40681 ctaagagctg tacgatcaat gaacgaaaag gaaatcccga accacgctat tttgatgttc
    40741 ctttagggag tatcaattct atgggacttc caaacttagg tttttcttat tatctagagt
    40801 atgctcttgc gtatgaaaaa gtgcaggaaa accaaaatca accgttattt ttttccattg
    40861 ccgggatgag tgtccaggaa aacttggaaa tgcttgagaa aatagaaaaa agtgggttta
    40921 atgggatcac tgaattaaat ttatcttgtc ccaatgtgcc tggaaaacca caactagctt
    40981 acgattttga ggccacttat gaaacactga aagaagtatt cagcatcttt tctaagccgc
    41041 taggaatcaa attgcctcct tattttgatt ttgctcattt tgatcagatg gctgatatct
    41101 tgaatcagtt tccattgacc tatgtcaatg ctatcaacag tgtgggcaat ggtttgtata
    41161 tcgatacaga acaagaagca gtagtcatca aaccaaaaga agggttcggc ggcattggcg
    41221 gagagtatat caagccgact gctttggcga atgttcgcgc tttttataca cgtttgaaac
    41281 cagaaatcca aatcattggt acaggtggga ttcggacagg acaagatgca tttgaacatc
    41341 tgctatgtgg cgcaagcatg ttacagattg gtaccgagct tcataaagaa gggccggaaa
    41401 ttttttctag aatcataaaa gaattaacgc agattatgtc agaaaaagga tatacgtcaa
    41461 ttgacgaatt taaaggcaaa ttacgcacca tttcatagca aagagacgaa ggtcatgatt
    41521 gatcttcgtc tttttttata aaaaacactc gtctgttcat tcctgtgcaa gcgtactcat
    41581 tgtatgttag acgaacttgt gggaaaataa cagaggcaaa aaggaggata atatgaatga
    41641 tgcaacagaa ttagcaaaag agcttaaaga aaaagaattt agttttcaag aactagttac
    41701 ggatatacag aaaaaaataa agaagcaaaa tcatgaattg aatgcgtttg tcgcgcttga
    41761 accattcgag agtaattccc acgagctatt gattccccag tcagaaaaag ggccattggc
    41821 tggtatccca tttcctttaa aaatgctcgg tcaagaaaaa aagggatggc tagctacttc
    41881 aggatctcgt ttatttgaaa cacaccgagc ttctcataca tctaattatg tgcggcaagc
    41941 agaagcgata ggtctagttc cttttggaca aaccaatgcg ccagagtttg gtttcaaaaa
    42001 tattacagac ccagtcatct atggcccagc aagaaaccct tggaaccttg aatgtacacc
    42061 gggcggatca agtggaggag ctgctgctgc agtttcatca ggaatcgttc ctttagctgg
    42121 tgctagtgat ggcggtggtt ctattagaat acccgcttcg ttttgcggat tgattgggct
    42181 gaaaccttcg cgagggacga tgccagttgg tccatatgct tggagaggat ggcaaggagc
    42241 tgctattgat ttcggcttga cagtttctat gagagacacg gaggctttat tttatgggat
    42301 gagaagtatc cattccggtg cgccatatca agtatcgcca gttgagtggc aaacacatcc
    42361 aagaaaaaaa cggttgaaga tagctttttg tgttgattca ccgatccact cacagattag
    42421 tgaagaggca gtacttgctg taaaaaaagc tgtagatttc cttggaaaag aagggcatga
    42481 tttgacagag attccttacc cactagatgg tcgtaaactg atcacgtctt attatcagat
    42541 gaatggcgca gaaacagcag caatgatccg ctcgattgaa acaggcatcc agcgagctgt
    42601 cagaaaagaa gaacttgaac ccatttcttg gactttgttc caatatggtc agaagctctc
    42661 tgccgctact tacatcgatt ctctgcatgt atgggatgaa gcagcaattg tcatggaaaa
    42721 cctacatcaa gaatacgatc tattcctttc accaacgact gcatttaccg cccctaaaat
    42781 cagcgaagat ttgcaaagtg atgcgataag agcacagatg gaacacatca gtgattgttc
    42841 tgaagtagaa ggtttagacg ttgtttcttc catgtttgag gagagcttga agatcacacc
    42901 ttatacacag ttggctaatc tgactggaca accagcaatc agcttgccta ctcatttgac
    42961 aaaagaaaac atgcctctag gaatccaatt tatggctgcc agaggaagag aagatttgct
    43021 atttcaaatc ggctatctat ttgaagcaaa tcatcagttc catttaccaa atccatggaa
    43081 atagcagaaa caaggagaag aagaatgaag aaaaaaagat tgtttgctct aataactagt
    43141 gcctttttta ttttaagcgc ttgcggtaca gctgccgcta atcaggaaga taacagctgg
    43201 agtaatgtag aaaaaaagaa agaattagta gtagcgactt ctggcacact gtttcccgca
    43261 tcttattata atgatcaaaa tgaattagtt ggttatgatg tagatttggc aaaagaggtg
    43321 gctaaacggt taaatgtcaa aatctccttt aaagaataca acgtggatgg acaaatcact
    43381 tctgtttcaa aaagagaatc agattttgct gcgaacgatt ttggtatcac aaaagaaaga
    43441 gaaaaaaaat tctccctttc agagactttc aaatattcat ttgacagtat gatcgtacga
    43501 aaaaaagatg attcaggaat ccactcactt gaagatctta aagggaaaaa agcagctggc
    43561 gaacccaata ctagctatat gcgtttagcg gaaaaacacg gagctaaatt agtcacatat
    43621 gacaatgcca cgaatgatca gtatttaagc gatgtagcaa atggtcgaac agatgttatt
    43681 ctaaatgatt attatctgca gaaaatggcc gtatctgctt taccagatat ccctgtaaaa
    43741 atactggaga acgtttattt caatgaaaac gaaagtggtt ttttattgaa agaaggaaat
    43801 gatgctctga aaaagaaaat cgatggcgta ttaaaagaga tgaaagaaga tgggacgaca
    43861 aagaaaatat ctgaaaaata ttttcaaact gatgtttcag tcaaaccgaa agaaacgatg
    43921 gctgagtcgg tgagtgagtg atgtactttc ctctaattga tttttccctc atgtggactt
    43981 cacttccttt cgtactgcaa ggcttggtat acacattagg gattggcttc gtgtcgtttc
    44041 ttttaggaaa tctggtaggg ttgcttttga cagttttagg tcttttggat tggctgcctc
    44101 tgaatgtatt tattcgtttt tatttatcgt tctttagagg cattcccgca ctagtcctgc
    44161 tgtttctgtt atattttggg ttaccttatc aattaagtgc cttaacggct tcagtcatct
    44221 gctttacgat taccagcagt gcatttattg gtgaaatcta tcgaggatca ctagcaggcg
    44281 tttcttcagg tcagtgggac gctggtttag cttctggttt ttctttcttt ggggtattga
    44341 aatatatcgt tttgccgcaa gcttttcgaa tctcagtacc ggcactcagt aacgtagcta
    44401 tggatctagt gaaaggtact tcgttagcag caacaatcac agtgccagaa atatttcaaa
    44461 aagcaaagat cataggcggt cggacattcg attatttttc tctctatatt ttagttgcac
    44521 tgatttattg ggtcatttgt atcgggatcg aaaaagtgca acagtattta gaaaaacgtt
    44581 ctatgcatca gtcaatctga aaaatagaaa tggtgctagc gtggctggca ccatttctat
    44641 tttttgtttc ttgtatattc tgcctagtat tttaaaacca tttcatgtaa aatgtaaatc
    44701 gaaaatatgt tcggaggtag aaaacatgaa gaccccgcta accatcgaaa tagaatcctc
    44761 gttataccaa tattgcatcg agcaaggcgg cttggttgta gaagaagtca cgatgcctga
    44821 tgaccaagga attgtagata cgcttagctg cttgacaaaa tttgatggaa gccgagaatg
    44881 gcgatgctat gagctgaaag tgacaaaagc agattttcgc tctacagcca aactgtcatt
    44941 tgttggacat tataattatt ttgttttacc aagtaaacta tatgaagaag taaaaactga
    45001 aatccctaca ggaataggtg ttttagtgta tcgtccgtac acggttgaag aggagatgcc
    45061 tgcctctggt acatttctga ttgcgaaaaa agcagcaaag aaagagcttg ctgtaccgga
    45121 agaagctttg acaaaccgct tcatggcttc tttattcagg gaagtaagaa aagcaaagca
    45181 aatggagcga ggcgtaaaat attttccaac agatcaattg tacaaagaat tgaaaagacg
    45241 ttcagaaaat caagatccat tttctaacga acgatattat gaacggtttt tagaggaaat
    45301 agctagtcag gcaatcaatg agttgcaaga agaagttatc gcgcttcagc atgattatga
    45361 atatttgagg caacaacagc agatccgtcg gttgcctaca gagccattgg agtgaaaaat
    45421 atgtactatc cttatttaag aggaaaacaa tttgacctat tagcattaaa agaagcactg
    45481 tcgcgaggat tgctctccaa taaaatccaa ccagtgatcg aaccagtacg tgattccgct
    45541 acgcttaaaa atgtgatcga attatttcaa aaaaagcacc atcgaatcgc tgtgatccaa
    45601 aatccccaag taggacaatt caaattattc gatcagcatg tgcacagttg gacagtcaaa
    45661 gaaaatagct ctgtcgtccc tgcacagatc ttaacgccag aaaatctcag tgaagtactg
    45721 gattcacctc cagcgtttct tgttttcgat ggacagcact acccaaaaga tacagaggtg
    45781 tggaaacagt tggcaggagt tgattcgaaa tttttgatac cagatactag tcgctttcgc
    45841 atctggctgc ccgaaaacaa aattgtgatc cgtgactctt ttcaaacgag aaagcatgtt
    45901 gaaagttatg cagataaaac agatgacttt tttagtgatg actatctttt tttccacgca
    45961 gacggatata ttggattttc tgatttcacg atcgaaggta gccgttattt cgataaaggg
    46021 ttccctagcc gagcgcttgc tatccatcta acgtatattg atgcttacgg caatatacgc
    46081 gtgaaacatt ttgtctctga cagtaacgac tctgctaaag accaagcatt gaagtttctt
    46141 gaagcaggag ataaaatgaa aaaatggatc atgcgtcacc atcatcaact cttgattact
    46201 tcaggaatga ttgaattatt ggctctttac cagcaacaaa aattccctgg actgggagtg
    46261 ttgaaaaagt ggtcacttat gcatcatttg gaacttatta gtcacctgct agatcatcca
    46321 aaagattggc ttaaatatta ttcaaaagtt caggaactat atgaagtgat ccaatgatta
    46381 gataatgtaa atgaaaaagg aatagaaaag aggaaactgg atgtatattc ggcaaacaag
    46441 gaaagaagaa gtagaagaag tggtagaaat cattaatgcc gcagcggatt tcattgcttc
    46501 gcaaggctct cctcaatggc aaaacgggca gaaaccaaca aaagaaacga ttttgaacga
    46561 tattgaaaga aaagaaagct atgtattaat agtggaagat caaattgctg gaacagctgc
    46621 attagtctca agcgtggatc ccgtttacac aaaaatagat ggtagttgga aagaatcaac
    46681 tggtccttat ttatcgattc atcgtgtcgc tttagcagaa agtactcgag gaaaaaaact
    46741 agcaaaaccg ttcttagaac atttgttgac gattgcagcc agcaaaaata tccaagatat
    46801 ccgtatcgat acttatccag ctaatgaacc gatggaaaag accatctatt ctgctggatt
    46861 cacttatcaa gggatgattg aatttccttt tgaacacggc gaaagaaaag catatcaaat
    46921 aatcatcaat tgactataaa atcatctgag caaagataaa gacattaaca ctactgaaaa
    46981 aaacaatcat atgatagcca agaggttgta acagaagtgg ccagcttcaa aaaacaagaa
    47041 agaatttccg aaaatgcttc tcaaattttt gtggaatttt agcgtatttt acgaaatagc
    47101 tgctttctga aactcccttc atcgagaggt cgtgacatag cttttgtcac gacctctcgg
    47161 cttatcctac gagtattatt cgatacattt atatcaataa tccttttttt attttatctg
    47221 cagcttcttg gaacgctcca tcgtttgaca cgactaaaag tgaggggata gctttcaaac
    47281 gtttcaactg tgctaaatct tctacataaa ccgccagtct ggctgaaatc tgttcagatg
    47341 aatctccacg ttttttcagg cgcgattgca atgtttcttt agagatcgta ataaagatag
    47401 gacggactac cgtcccgaaa tactcatata aatgccaaaa accatttgct gtcaaaacgg
    47461 cgtaacaatt tcctactgtc agtttctttt taatttctgc tttactggaa ccatatttat
    47521 gttgagcata ttggtcccac tctgcaaact catttccctt gatcatctga ttgaatgtat
    47581 tgtcagaaac aaaataataa tcctcttgat ctttttcccc aggtcttggt gatcgattcg
    47641 tgtaagtaat gatcttttgt tccggctgaa aaatagcttc tgcgagtgaa gtttttccag
    47701 aaccagaagg accgataaat acatagcaat aattcattgt catttctcct ttgatgattg
    47761 aacaagtgaa aaagctttgg aaaatatttc caaagctttt aaaagtaact ttgctttttt
    47821 gtatattata ccagcaagcc agtcacaata gcacttaaaa agctgactaa agtcgctgtt
    47881 agcaaaattt tcaatccgtg ttttgcgaca agatttcctt tttcttcatt taatcccttc
    47941 atcgcaccag aaatgatccc gatagaagag aagttggcaa atgaaacgag gaagacagat
    48001 ataattgctg ttgtacgctc agtaaaatgg aaattaccat ttgctaattc tgtcatagca
    48061 acaaattcat ttgtaaccag tttagtcgcc atgatactac cggcatccac tgcttctttc
    48121 catgggattc cgctgatgaa ggcaagaggg gcaaagatgt aacctaggat ctcttggaaa
    48181 gtgatgccga atatcccgtg gaagatagca ttgatcatgg caatcaaagc aacaaaaccg
    48241 ataagcatag cagcaaccgt gatcgccaca tggaaaccat caagaatgta ttctcccaac
    48301 atttggaaaa atgtctgttc tttgttttct tcaatgatca gctcatcttc tttttcttct
    48361 aatacatagg gatttacaat tgaagccaga atataaccgc caaataagtt caaaacaagg
    48421 gcagtgatca catatttaga atcgatcagt gccatataag atccgacgat cgacatagaa
    48481 actgtagaca tagccgatac actcatggtg aacaaacgtt tctcagatag gaagggtaat
    48541 tcctttttta tggaaataaa aacttccgat tgtcctaaaa tagcagaagc tactccatta
    48601 taagattcca atttgcccat cccgttgatt ttacttaatc ctagaccaac agctttcata
    48661 aataatggaa gaatcttgat atagcgtaga ataccgataa tagcagaaat aaatacaatt
    48721 ggcatcaata cggaaagaaa gaaaggtgca cttcctttat ttgctacacc ggcaaaaaca
    48781 aagtcaacac cttgcccagc aaaagcaaga agatgatcaa acatttttgc caatacagaa
    48841 acaaccgctg taccaaaagt tgtacgtaat aatacgaaac caagaacaag ctgtaaaacg
    48901 aacatcacaa ttagtggttt caatttgatt gcttttttgt tactgctgat caaaaaagca
    48961 agccctaatg tgacaaataa accaataata cctaataaat aactcaaata atcactccta
    49021 ttccaaattc cgttttattt tacctgtttt gcaaataaaa tactaatctt tagtgaaatt
    49081 ttcattactt ttttagagtg aaacgcattc attttccatt agaaaataaa gcgaacaaaa
    49141 taaaaggttt aaaaagtgta acgtcttagt aaagtctata aaaaaacgaa actatcgatt
    49201 aagctaatag tttcgttttc aacatttata agtaaacttt ttctattggt aatatagatt
    49261 ttcggaaggg tagacaggtg cgcaggtaat atcgattcct agttttttca atgtttgttc
    49321 atcattttta ttgaccatca cagtagagtg ggcttgtgct ccctcaagtt cagctagttt
    49381 atcataagca acttgagcga ttggattcgt tactgcactg attgataaag cgatcaagac
    49441 ttcattgatg cttagtgcat ccaaagagga atgaagtgtc tttgatttca atccttgtat
    49501 tgtttcaaga actaatggtg acaataaagg aatgtcatct gcgatatggg ctaaatgttt
    49561 tactgcattt aagataactg ccgctgacgc atccatcaat gaacttgtac gcccggtaat
    49621 gatgacttca tctggtaatt cgattgcaat cacagcagaa ggatcttttg taggactttg
    49681 cgcttgaatc ttatctgcat agtcatgggc agggactacc acgtttcggt cttcaggacg
    49741 taaaccgact tcttccataa tcagtttgat tcgattaact gcttcttcgt cgatcaatcc
    49801 ttttttgaag tcgcattctg tttggaaata acgacggatg atttcttgtt tagaggcttc
    49861 ttggacaacg gtatcatcca cgatcccaaa tcctacacga ttcacaccca tgtcagtagg
    49921 agattgataa acagattctt taccagtaat tttttcaata atacgtttga ttacaggaaa
    49981 tgtctcaaca tcccgattat agttcacagc tactttattg taggcatcaa agtggaagga
    50041 atcgatcata ttgacatctt ttagatcgac tgtggctgct tcataagcaa tgttcagcgg
    50101 atgtttcaac ggaacattcc atactgggaa agtttcgaac ttggagtaac cagctgcatg
    50161 tcctttttgg ctttcatgat acagttggtt caaggaagta gcgagctttc cacttcctgg
    50221 gccaggagct gtcactacaa cgattggttt agttgtttca atatactcat tttttccaaa
    50281 accatcttct gagacgattt tttctacgtt gactggatag tcttcgattt ctgagtgttt
    50341 atagaccttg atgtttcgtc tttctagttt attgataaag actttcgtgg caggctgtcc
    50401 actatagcga gtgataacga cactgttgat taataagcca taaccacgta attcatcgat
    50461 taaccgcaag atatccatat cataagtaat cccataatca ccacggatct tattacgttc
    50521 aatatctcca gcatagacgc aaatcagtat ttcagcttga tctttcaatt tttgcagcaa
    50581 tttgattttc gcatcttctt caaatcctgg aagtacacgt ttcgcatgct tgtcgtcaac
    50641 tagcttccca ccaaattcta aatataattt gtcatagtgg ttcactcgtt ccaaaatata
    50701 cgctgactgc tcttcaatat atttttctga atcaaaacca atttttttca ctaggttccc
    50761 tccttaagta ctaaagcatt ttttcatttt tttgaggatt cgtcaactgg aagagcgaaa
    50821 ttcctcaaaa aaacaaagaa aatggtttaa accaacttgt ctagatagtt attcattggt
    50881 atgatagttt ttgataagga aggtgctaca tgaaaaaaag acagaaaaag aaaaacgcat
    50941 ataaacacta tatccgttcg atttttaccg gttatgaaag aatgcttgaa gatcccgaat
    51001 tggaacaatt gacgtttact tatctaaacg aagaaacgca gctaactcgt gatgagcatc
    51061 agcgcattca tttcacaaca agagatctgc ctagtaaata aaaaataaga taaaggtcat
    51121 cggattcgat tctgtcctat cagatggaaa gactagttga tcgaaaaaaa ggctgtacca
    51181 aattttggtg cagcctgttt tatggagcat tgcccgctct tttttataac aattttttac
    51241 agaaaatggt actattgaag tattaataag tgaaaaacag atgagtaaga ggaggcaagt
    51301 agtatgaaag agccagatac aaatgcaaat tatgagccag acgaactaga ggagacgaat
    51361 gcggatcagg atacaggaca agaatcgtct tctttttacg atatcaaaga aaaagcaagc
    51421 atgaatcttt cccaattatt agaagactta caggcttttg aaaaagctgt ccgcgaagaa
    51481 gatatccctg agatctaccg tttatacaat ggccgattga atgaagaatt aaaaagaagc
    51541 tcaaatgaaa atcacgagat cgatcaattg ctgatgcgta agatccatga tcgtttttta
    51601 caggaatttc cttttatgga acaagtagaa aacatctcgc caacgatgag ctattacaaa
    51661 atcggcactt attaccatga tcggcccacg gtcggtattg atgcaagtct gccagaaatt
    51721 tttgttttgc ctaagatcga tgaagagtgg gagaaatatt cccaaccgga gtcaacggac
    51781 tatgacaaaa aaatcaatga gctagacgca aaggtgatca ctgctcagac agaaattgaa
    51841 cgtttagatg aacaaataaa agaaatcaat cgacaaatga ctgatttgaa cgacaataaa
    51901 ggattcttga atcgtaaaaa aatcgaggaa gaaattcaag aattagagaa gaagaagcaa
    51961 gtactatcta atgaaaaatt aggctggctt ccttatattg agacgcctga aacaatccag
    52021 cagcaaaaag aagcattgaa gcaagaagca agagcagacc agcttcgtgc agccatcgta
    52081 gaaaaagaac aaaggcaaat cagacgctat ttcggtagca aagagggatt cggtcaagca
    52141 atccatgaat tcttgatgaa ttatcttggc aatgagaatc ctaataatca atctaatgaa
    52201 ggaggttccg agtatgaatg aacacgatga agcagaatgg acaaaaaatg aagaacaaac
    52261 agaagatcat gaagaaacga acacttcatt ggaagaacaa acaagtaatc ctctggatga
    52321 cacagaagaa atccctatgc tagaggaaac aaaaatacac gaaaaagaaa aagtaactcc
    52381 gacgaatacg aatactgcag aaaacaccca tgcttacgaa ataactgaaa atcccgggta
    52441 tttagaagga aaagagcaag atcatcaaga tatcgtcagt ttgattgaaa cagcggaagc
    52501 agaattagcg gatttacgta tgagaaaaga tttgatcgaa tcagattttc cacaattatt
    52561 agaatcatat gatcgtttta tattgaatga agaaccaatc tccacgatcg gaaagacaag
    52621 cctgatcgaa tacttcacgt atgaattact gaaaccgttg aatgatattg gtctggaacg
    52681 gtcaaattca gcttatgaca catggaaaac aagacatttt tcgatcaatt atacgttgaa
    52741 tggacaaaac gaattagtct tttcctttgt attaccgacc atcgatcaac gataccaagt
    52801 ggaatcgatg agtctcctaa acgtatcacc agagacaatg gaaatcaatg tccaagatga
    52861 ccgggtgctt tctttgatcc gacactggtc agtggatcga gtattctctg cagggcagat
    52921 cacgatattc aatcacaaat tgaatcaatt attagcccat gcaagaacac ttggttttac
    52981 cgttaatcag acattactag acaatacgaa gccacttcgt ttgaatcttc agagcgaatt
    53041 tgaattgacg aatgaagtat tggatgatat ttttatcgtg gcaatgaaaa atccatccta
    53101 cgatatggaa aagatcaacg aaactactta tcaagtacga ttagataaag gacagtcttt
    53161 aacgataaca acaaacgaaa aagatcaaac agtcttgtcg atctcatctg gagactaccc
    53221 acgatctgtc attgatttct ttatcaatta cgaattcttg gtcccattaa tggtgagaaa
    53281 gtcctgattg gataagttgg attaccagat gtcattcaga taattctgtt ccaaaggact
    53341 tgcggcagtt atccagaata attgtcacaa gtcttttctg tatgtactaa atggacgtga
    53401 ataacttgct gatgaaggag ggatttcatt aggaatgtcc acaaataaaa tagcacagct
    53461 tagcttattg tctgctgctt gtgtagcagg taggatcgct tttcaattta ttccgaattt
    53521 ccagccaatg actgctattt ttttatttat agtactttac ttaagcttaa aagatgcgtt
    53581 aattgtcatg agtctttcta ttgcgatcag cagtttttat tttggtgttg gaccatgggt
    53641 catcggccaa tggatcagct atactgttgt tctgagtttg ttttcaatcg tctgcttgag
    53701 aaaaacagtg caaaggaatc tatggttaaa gggagtctgt ttttttctgg cgggcatggt
    53761 ttacggaata ggtatgaccg tttttgatac gctgttatat cgtttgcctc aaccttggat
    53821 ctattacctt caaggggtgt cgtttgattt gatgcacagt ataggcaatg ttgtgttctt
    53881 tcttgttttt ctgccagtcg tcaaacgttt ttacaatcat tcaggaggaa aaaatgaaaa
    53941 aaataattta tagtttgctt gcaatgagtg tcagtatact cattttgaca agttgcagta
    54001 caacctatac acaatcggct tccaaccaaa aggaggaagt aaaaacatcg caaaaagcaa
    54061 caatcacgtt acaagaaaat ggtcaaaact tttcggaaaa agaagtgttc ttcaaaaaag
    54121 gcgatgattt actgagtatt ttgaaacgaa attttgaagt caaagaagat aacggcttca
    54181 tcacttcgct tgaagggcac tcacaggatg agaaaaatca actctattgg atgtttactg
    54241 tggacgggaa aagtgctact actggtgcca aagagatcaa attgaatgat ggacaatcgg
    54301 tcattttcaa tttgtctaaa ctataagttt cataaaaaac tgttaaaggg cgaatattgc
    54361 cataattcag tgagttcagt tgatgaaaga aggaaaataa catggaaaat tttaaaaaaa
    54421 gcggaatgtt ttccgtaatt gctgctctag gggctaatat tctagttgct atcagcaaat
    54481 ttgtcggcta tgcaatcagt ggcagtgccg ccatgctaaa cgaaagcatc cacagtatcg
    54541 ttgattgcag caatcagatt ttgctgttat tcggtgataa acaagccaat aaaggacaga
    54601 gcgagttgca tcaatttggt gaaggacgag caaaatactt tttcagtaca atcgtcgcaa
    54661 tgatgctttt cttcggcggt ggggcacttg gggtgatgga agcttttgaa aagttgacgc
    54721 atccatccca tgaagtgggt aatccgatca ttgttatagc aatactgtta tttggtttgg
    54781 taatcgaagg aagttcgtta cgcgtggcaa tgaaagaaat caaagaattg aatactgaaa
    54841 aactttccac gatgcgcttt ttgcgcgaaa gtcgacacag tgaaatactg attattttta
    54901 cggaagactt gtgtgctgta atcggtttgg tcttggcttt agcaggaaca atattgactt
    54961 atgcaaccgg gattgctgca tttgatgcga tcagcggatt gctgatcggt ttcttgctga
    55021 tgggagccgc cattttccta gcaaaagaat tttatagtct gatcatcggt gaaagcgtga
    55081 cagcaagcga tttatcaaaa atcaagttag cttttgaacg tcctgagatc agtcggctga
    55141 tcgatataaa aacagttcat ttaagtccaa cggagatttt agttgcagca aaagcagata
    55201 tcgttggtaa caaagagaat gaagcttact cggtcatcaa tgatattgaa aaaaatatgc
    55261 gtcagtctct tcctgacaag aagatgtata tatacattga aacagataaa tatgacccaa
    55321 attattctcg taaataaaac gtttattcat gaattgaagc aaaaatgaga aaaatataat
    55381 cttgttttta aataaaacgg ctacaattta gcgaatttat gttacaatga gtccgctgtt
    55441 tatttgttgt aattaaagga gatattttaa tgaacaaaaa gaaaagtgcg ccatggcttc
    55501 aagctttgca tgcagtgatg ccactttgta taagctatat accagtagga ttagcttgcg
    55561 gagtattgtt gcaaaaagtt ggatttgatc ctctcttatc aggactgtta tcgattctgg
    55621 tcttttccgg tggcgcgcag tttttagttg catctatgct tacgacgcaa gcatcatttg
    55681 caacgacatt attgatggtt ttctttttag aattacgcta tacattatta ggagcaagtc
    55741 ttgccggttt tatgaaaaaa gaaaagcgga cgtttttggc tgtcttttct caatcactga
    55801 atgatgaaaa ctatgcggtg aactacttaa agttttcaac tgacccttcc tggaataaaa
    55861 gaaaggcttt atatgtcaat tggttctcaa tgactgcatg ggccggtagc aatatgatcg
    55921 gtaatttttt cggctcggtg attcgagtag atgctgacct tgtccatttt gctttgacgg
    55981 ccatgttcat tttcatgttt atcatgcaga tgaaaagcgc actactgatc tttacaggtt
    56041 tattctcagg cgtattaggg gtcgtattca tggtattatt ccaaaatact ttcggattga
    56101 ttgcagcaac agtcattgct tcatttgccg gatttatgct ggagaaggca ttcaaaaaag
    56161 aaaaagctaa gaaactaaga gaccgcggta aagatgtcaa tgagccgctc ttcaacttcc
    56221 cggaacagga ggccaatcac catgactaaa ctatatttgc tacttttagt tgcttgtctg
    56281 ttcatcgtgg catatatccc gcgcttgttc ccgatgcttt attttactca tcgaaaagtg
    56341 ccatcctggt tcagtgactg gatgaaatat gtaccggtgg cattatttgc ggcgttagct
    56401 tttaaagatg ttttcattac tcatgaacat ctggatattg cttggaatat caaaatagct
    56461 gcaatgattc tagtagcagg cgtggcttac aaaacacgtt cgatggcgtt gtcagttttg
    56521 acaggacttg cgtctgtctt tttgctgtct atgctttaaa ctgttttatt ttattaaaaa
    56581 cagagattgc gacataagtt gttcaaactg atctatccga actgcatttg caacagtcaa
    56641 ttctggatgc aagtttattc gtagggataa aaaagattag tgttggctta tgatgcaagc
    56701 tcttttttat tttaggaatt agagagggat ttgtccttct atgatttttt gctataatag
    56761 ggaagatgtt tattttatga aagaatagtt gagggaattt aaatgaataa aaaattgatg
    56821 caaggaacat tttggctaac ctttgctaat cttctatgta aagttttagg ggtagtctat
    56881 ttgattccct ggctaagtat gatggggaac aatcaagatg gtatgcttgc tacgacattg
    56941 tataatgttg gctatcttcc ttatggattg ttcctgatgc ttggtacagt cggatttcca
    57001 aatgcgattg caaaaaaagt agctgtagcc acaaaagaag gagataacgc tgcttgtcgg
    57061 ctgattttta gaagtacgat caatatcatg tttgtcatcg gtatcgcctc tgctgcactg
    57121 atgtatttat ttgctccttt actagccgga atcagtccga ttgctaacgt taataatggg
    57181 atactagcta tcagaagttt atgcccatct ttgattgcta tcccaattct tagtgcaatg
    57241 agaggatatt tccaaggaaa aaatgatctg cggccttatg gaacttcttt gattatcgaa
    57301 caggctgtgc gagtgatcgt tatcttggct ggtacttatt acttgcgcgt attgactgac
    57361 ggaaccatat tagaagctgt attgatcagt acagtcgctt ctttcttcgg tgggttagct
    57421 gcgattatcc atatgtatat cgtcggacgc agaaaagact tcttcgaact taaagatttt
    57481 ttgatttcca gccgttattt cgaaagagaa aaccgatctg cctctgtctc tatcattcgg
    57541 gaaacactac cgtttatttt tgtcggctca gtcattacta tcgttcaaat gatcgaccaa
    57601 gtaacgatga aaccactgct tcactttttc cgtccagaga tcgcagatca gcaactggaa
    57661 ttcttattca gccgtgcttc tgtcaatcca aataaattga cattgatcct gatctccatg
    57721 gtaggaacag tagctataag cagcttgcca atattaagca cgatgaagaa aaaagatcgg
    57781 atacaaatcg aaaaaacagt aggagatagt ttttcgattg cgttattgat tcttcttcct
    57841 tcattgactg gaatgtcttt attagctgga ccactataca cattgttttt tggctatgat
    57901 cctgaaagtg tcggatattt ccaaatggct ttgctagctt ctttgttttt ctctttattc
    57961 acgatcctat ctacgatgct tcaatctttg aatcaccatc gttttgcgat ccgattaact
    58021 gtagaagcaa ttatcctgaa agtcatcttc caagtaatcg gattaggatt agttggcgga
    58081 tacgggatga gcttatcaaa tggcttagca ttcggtattg tctttgttcg cggctatcac
    58141 tttatgtgca aagaataccg aatagcacct ttagcaaaga tcagcaattt tttcttaaaa
    58201 actttccgct ccaccctgat tatgcttgca gtatgttttg ccgttttctt tttgctgaat
    58261 cagcgattgt caatggaatc aaaaagctat gcaatgattt attgtgtggc tgtaggaagt
    58321 attggcggct tagtattttt attttctcaa ttcggaaaaa atgggtttcg aatgttgaaa
    58381 aatgttaaac atcatagcag aagcaaagaa taggttaact aatcgttttt tgctgtcact
    58441 tgaaaaacgg caactcgtat gattacgctt gtcgtttttc tattttccaa ttttagtttc
    58501 atatctaatc ttacttatga tatagttata aggtctggaa aaattctttg aaacgaggaa
    58561 attaaacaca tgaaacttgc agtagttaca gatagttcgg catatctgcc ggaacgtatc
    58621 aagaaccatc ccgacttatt cgttattcca atccctttga ttatggatgg gaaaatttat
    58681 aacgaaggaa tcgatatcga agcggatgaa tattatggac ttttaaaaaa cagtaaagat
    58741 tttcctacta cttcacaacc tgtcgtaggg gaagttttgg gtttatatga ggaattgaaa
    58801 gagaaagggt atgacacgat tttaagtatc catctttctt cagggatttc tggctttgtc
    58861 aacacattat ttgcgatgaa agatgacatc agcggagtaa cggtcattcc ttatgactct
    58921 aagatcacta gtatgccgat gggacacatg gtagaagctg ccttagactt aaatgatgaa
    58981 ggtcagtccc ttgatgaaat acttgcacat atcgatcgaa tccgagataa tacctacgct
    59041 tatctgattg tagatgattt gaacaattta gtacgaggag gacgtttgac aaatggtgca
    59101 gcgctgattg gcagcttatt aaaaatcaaa ccgatcctga cattttctga agggaaaatt
    59161 gttttattcg aaaaaatccg ttcaagtaaa aaagcatttg ctcgagctga agaaattatt
    59221 ggtagaagaa ataacgaaat acaaccgcca gtcaaacttt acgtgataca tgcaaataat
    59281 ttagaagtag cgattgcgga gaaagagaaa ttgcagaaaa aatatccaaa tgcagaaatc
    59341 gaaattggtc atttcggacc agtcattggt acacatttag gtgaaaaagc catcggcatt
    59401 gccatttcag cgcaataatt ccttttattc aaaaaacata ccaaaaatat tccaacatca
    59461 tcttggactt tctacatgtt actaatgagc gtgtaaaaga acgagatggt gtttttattt
    59521 ctatcaatga agctcttttt ctttgcaatc ctcacttcaa tcctctataa tgtcgcatat
    59581 agtttagtaa atgagtaaac tactaattta cttatttact aaaaataaaa ggatgaggag
    59641 ttaaaataat ggaaatacca acaaatttaa aacataaacc agtaatcgtt gtagaagact
    59701 atgataaagt tgatggaaga aatgcattaa atacggatgc aaaagggctt tcactgggcc
    59761 ttgctcagtg gaatgatcgt ggaaaagtcg atatctcagg caaggtatgg cgacatactg
    59821 gagaaaaatg gtcacgacag tcggaagaat taccaatcac acgtatttta gatttagcga
    59881 tcttagctgc acaaggaagt ttatacttcc aagatgctta tcgttatgaa aaattttatg
    59941 atccagaaaa tccagtcgta gacatcattg gattacaagg gaaccgaatg acggtagaag
    60001 tagataccaa aaatccaaag atcgatgaag acatcatttt gtattacgat acactacaaa
    60061 aagacggaga actgattggg gaacgattcc gtattttaaa acgtctttta gatgagctag
    60121 gatattaata gacagagatg atcaaaaggg gaagagaagc atggagaatt tctcactaac
    60181 agaaaaccga accttttcac ggctagaaaa gcaaatgatc tggaagaaac cgaaaagcca
    60241 tcggacaagt gcagaagaat ggcggatcgc ctccgaaatc aaagggaatt ggcaagatcc
    60301 tgaaatgaaa atcagtaacg tacttttgga aggagatgcc gggtcgggga agacacaatt
    60361 agccaaagca ctatctgctg atctgcaact tccctataca aaagtgacct gttttgcaga
    60421 tatggacaaa tcagatgttt tcggagcctt attacctgta gtagattcta ataaggaaca
    60481 agaccaagaa ttactagaag ctatttacca aacagataca cttgaagctg tactgacact
    60541 gatccagaac cattacggca ttgatccttt ttctgctaaa gaaaaattag cagagctagt
    60601 tcaaaggatc gaagctgatt atccagatgc aatccattac agctattacc cttctgaaat
    60661 cgttcgagcg attgaaaaag gatatttatt agagattcaa gagccgactg tcatccgaga
    60721 tgcctctgtt cttgtggcac ttaactcagc gctcgaacca aatgggatgt tgaatttacc
    60781 gacaggaatc attcgtcgcc atccagattg cgtcattgtg atcactacaa atcgaaatta
    60841 ccaaggaaat cgcccattaa atgaatcttt aagagatcgg atgcaacatg cggaaaaaat
    60901 ggatcttcct gccttagaag tcatggcaga acgtgcgatg gcgaaaacta tgatccaaaa
    60961 acaagaactt ctcttaaaga tggcagagat tatccgtttg ttggatgaaa ctgcaaaagc
    61021 taacgccatc aaaggtgtag caggaatgcg ttcttatttt tattgggcaa atacctataa
    61081 gcaaggacaa gatttactcc agtcgattta tccaaaagtt ttgtataaat tatccactga
    61141 ttcagatgaa ttggcaattc ttgaacaagc tttgtctgac agtggattgc tactggaact
    61201 tcaggacata ttgagaaaag aaaaatgggg tcatcctcaa tctgagcata caaaaggaag
    61261 aaccattagc gccgaagaag caaatgaacg aaacatcact gaaaatgctg aagaaattct
    61321 gcgcttagat gaaaagaaat cgttgtctgc tgaagaacca aatgagggag aagagaaaca
    61381 agaagaaaca atagaaaaaa acgagattcc tcctcaaatg caaaaagaac gcagtagcga
    61441 tatcgaagga aaaaatcaaa aagaacaaca aacaggagat gattctcaag aaatgtctgc
    61501 ttctgacatg gaagcacatg ataaggaaat caagaagcaa ctgaataaag aagcgcgaca
    61561 aatcatgaag gaaacgattc atgaaaaaga aggtctcatc gttcaccgac cagctttcca
    61621 aggaaaaacg ccggaagcac gtgagctaca catgcaagta atgccaatag tagaatcact
    61681 tagccggcaa attttagagt tactggataa tgaacaaaca gagacgtacc aaaaaggaaa
    61741 atacgaaggt cagcggttca atgcaagcaa agtagcatat ggtgatttga gaaattttga
    61801 caaaaagaac ccgccacatg agcaaccttc tttagcggta gctgtacgga tcgatgaatc
    61861 tgggtcaatg atacgggatg atcggatcga agcggcaaaa aaagcagcga ttgccattgc
    61921 cgaattttct aagaaagtcg atatcccatt gttgatttac ggagatacag cagaccgttc
    61981 gtcaagagaa aagacttctt tgttttctta taaagaattt gaagacggat ttcaatggtt
    62041 aaatgaaaaa ttagtcacta tgaaaccaag gcaaaacaat cgtgatggtg ctgcacttcg
    62101 tttagcagca gaaaaattaa acagacaatc cgcaacaacc aaactgttgc ttaatattag
    62161 tgacggtcag ccaaaagcgt tgccggatta tacaggcaaa aaagcaaaag aagatatcca
    62221 gtctgttttg aaagaatatg aacgtcaagg aatcctattt gtctccgcag ctattggcca
    62281 agacaaagaa gaaatcaagt cgatctacgg tgaaagtcgt tttgtagata ttactgactt
    62341 gaatgaattt cccaagcaaa tgattcaact gattgcccgc tatctatgat aaaataaagc
    62401 tcaacgaacg cacttagcag attcgttgag cttttcgttt ctagttaccg gtaacaagga
    62461 tacttctaaa atagaatcgg ttataatcaa gagggaccgt taaaggagtg aaacgatatg
    62521 atacaagaac aaaaatggtg gaaagaagca gtaggctatc aaatctatcc tgctagtttc
    62581 aaagatagca atggcgatgg tcaaggagac atcaatggga tccgtgaaaa acttaattat
    62641 ttgaaagatc ttggtatcgg ctttatctgg atcaatccga tctatcaatc tccatttgtc
    62701 gataatggtt atgacgtaag tgactatcaa gatatagaag agagattcgg aacgatggaa
    62761 gattttgatt tattgctaaa agaagcacat gaattaggga tcaaagtgat tatggatctt
    62821 gtcatcaacc atagttcgga tcagcatcaa tggtttgaag aatcgaaaaa atctaaagaa
    62881 agcccgtatc gcgattatta catttgggtc gacggggtag atggcaaaga accgaataat
    62941 tggacatcga ttttcggcgg ttctgcttgg gagtattctc atgaaactgg acagtattat
    63001 ctgcatgttt ttgcaaaaga acaaccagac ttaaattggg aaagcgagaa attgaaagaa
    63061 gaactattca atatgatccg atggtggttg gataaaggga tagatggatt tcgtttagat
    63121 gcgatttctc atgtaaaaaa agatgaatat tcagtaaaag ccacagagaa ccctttctca
    63181 ccctttcaaa atgtctcagg aatcgaagaa catttgaccg atttgaaaca tgtttttgaa
    63241 gagtacgata tcatgactgt cggagaagca agtggtgtca ctgcagaaga aggaccacaa
    63301 tgggtaggga aagacggtta tttcgatatg atattcgaat ttgatcatat ccatatctgg
    63361 cagcaagaaa aagaagggca attagatgtc cttaaattga aacttgcatt aagcgcttgg
    63421 caaacttcat tggatggtat cggatggaac gctttatata tggaaaacca tgatgttcct
    63481 cgtgccgttt cagtgtttgg agatactcgt cccgattttt gggctatgtc tgcaaaagca
    63541 atcgctatga tgtatttctt tttgcaaggt acgccattta tttatcaagg acaggaaatc
    63601 ggaatgacga atatgccctt tgaatcgatc gatcaagttg atgcagtaga ttcgaaaaga
    63661 ctttataaaa ggctgcttgc ggaaggtaag acaagagaag aagcattgga tatcattcgt
    63721 gaaacaacga gagacaacag caggacaccc atgcaatgga cttcggaaca atatgctggt
    63781 ttttctacac atgaaccttg gctgatcact aatccaaata ccaaaacgat caatgtagaa
    63841 caacaagaat atgaaccaga gtcggtcctg caattctata agaacatgat ccgcattaga
    63901 caaaccaata aaggtctgat atacggttct tataaagaat atcttcatga acatccacaa
    63961 ctttatgtct atgaaagata tttagaagat gaacaatatc ttattatggt aaacttaaca
    64021 gaatcacttg ctgactatga acttccaaaa gaagcagatc agtcctggac attactcttg
    64081 tcaaattcct ctagcggaga atttgaagct aaaggcatac tagcacctta tgaagctcgg
    64141 ttatataaaa caaacaagta aaacttcctc gttaaagttc attagttgga ctttgcgagg
    64201 aagtttttca gattgctctg tcaattactc atttcaataa ttcgctctag gaccaccgat
    64261 atatttagga cgagagcgaa gggctgtcac gtgagcttgt ccaagggttt tcaaacgagg
    64321 tctgacaggt acttggacat gtttgatatg cataccgatt gatgtgtcac cgatatcgat
    64381 accggcttgt ccaactacgt gttccacttc gacaggatca ttgaactggt caaaagcagc
    64441 aacagaacaa gcacctccag catgtagtgc aggaacaaca gagacaattt cgaaattttt
    64501 tgcttctgcc actgttcgtt ctactactaa tgctcggttc aaatgttcac aaccttggac
    64561 agctagcgca atttctttag gatccaacaa ctcttttaac gtacggatga tccattgacc
    64621 aacttccgca ctggaatttt ttccaatatg tcctccaacg acttcgcttg tgctgcatcc
    64681 taaaacaaaa agatcacctt ttttcaagtg tgcctcagcc aatatgtcat taactatttc
    64741 agtcaattgg tcttttaatt ctttttctga caacttcatt ttctaaaacc ttctttttca
    64801 attaatattg cttccgtgct tgaatacgtt gaagacttgc agttatagga aaggcaagtc
    64861 ccattccaat cagattttgg aagatgtttc ctggtataga agccactcca gccggccaat
    64921 catataaaat ccaaccggcg ataccatagc cgatgatcat aactaagctt cctaataaaa
    64981 gccctaatcc ccacatacga gtagaagatt tgctgaaaga accagcaaca tatccttgta
    65041 acccgtggat cactaatgaa aaaactgccc actgcggata tcctgaaatc aaatcgatca
    65101 atagaccact ggaagcacca acaactaatc cacccgttgg accataaaga aaagcagcgg
    65161 tatagatccc ggcctcgcat aatgtcacaa atccattcgt agccggtaca gggatcaaaa
    65221 ttgttaatga aagggcaact gtcaacgcaa tcagcatagc atagatcgtt aattgcttag
    65281 ttttcatttc tcattcctcc tttttgaata ccgccagacc agacacttcc ggtatgatcg
    65341 ttcatcagca cgccattaga aatacaatgg gcaacaaatt ttttactttc tgctactgct
    65401 ttggtaaaat ctgcccctaa cacaagattc gctgttattg cagaagaaaa ggcacaaccg
    65461 gccccgttta ctgttgtagt gtcgattttt ttatgagaaa atacctcata atgatcaatt
    65521 gaatagagaa gatccacagc ttcatctcca gccatccttg tgccgccttt gatcacaatg
    65581 ttttttgttc ctgaagcagt gagttcttta gcgagatgga tcatttctgt taacgaagag
    65641 ggaagagctt gaccagaaag taaagcagct tctgccaaat taggcgtaat catcgtaaca
    65701 agtggaaaaa gttcttcgat gagctgcgaa atatacaatt gattgatcac agcttcagtt
    65761 tctttgaatg ccaaaacagg gtctaaaatg attgggatat tttgttttgt ttttatgaag
    65821 tctcgaacaa ccatgattgc ttcacttgaa ttcaataacc caattttgat accatctaat
    65881 gaagtcattt tatcaatcga aactaactgt cgtttaagca attccaaaga tatagattcc
    65941 agcataaatc gctcattaat atctagtgcc cctatagaag tcaaggcgct tagtccgaat
    66001 agaccaaaat tctcaaaagt ttttaaatct gtttggattc ctccaccagc aaatggatca
    66061 gaaccgccaa ttgtcaagat tcttttcata acattttcct ccatgaataa gagtataacg
    66121 aaattttcaa aaaagaaaaa cagccaattg gcatattttt atctcatcca atttaaaaaa
    66181 acaaaaagaa aagaaagacc aaaatggatc tttctttcct taaatagtta ggacttttgt
    66241 gattttaatt ctttctcgat ttgaagccgt tgcactttca ttgtagctgt tcgcgggatt
    66301 gcatcaaaat cacggatgat agggacgttc aagcgaggaa gttcatggac ttgctcccac
    66361 catcgattcc aatccatttc tttatcagga gctaaagcaa taatcggttg tggagaatga
    66421 tttttatccc ttacaatcac tacttctgcc aaaaaatcta acgaatctaa taaaaagtct
    66481 tcaatagcta atgtactatt gatcgtttcg atcaaatcca cttgccgatc tttcaaaaat
    66541 aggtggccat gcttatccat aaaaccgtaa tctccgctat cccaccaatc gccataaaca
    66601 ttttcctgga accgtgcatc ttccttgtaa taagtcaaag cccgtccttt agacagtaat
    66661 tgtatatgac catctgtgtt ttcaggtagg acattcccaa ctgaatctgt aatccgagcg
    66721 cttgtcatgt cttccagtcc aacgcccata tctcttgcat cacttgtttt caaactctct
    66781 agtgtatgag ccttaagaat cattggtccg cattcacttt ggccatatac ttgaagaaat
    66841 accgcatcct gtgccatcga cgttcgcaaa aatgtcttca ttgtctggtt gtttatagca
    66901 tcaaaagtgg agtgatagta tcggataccc gaaaaagctt ctggatgctc cttagcagta
    66961 aaacgccact gaacaaagtt attcggatgg gtctctagtg caattggccg gtgagcttcc
    67021 aacatatgaa caacttttga actttgtgcg tttgctaaag gcatcatagg aaatcccatg
    67081 gacatcaaag aagagatacc aatattgaat ctggaatgca ctggagagat gtgaaaagcg
    67141 attaatttct tttccgaaat ttttgtgaaa actgtttttt gccatttcgt ccgccatccc
    67201 atagaatgag cagaatgaca aataagttta gggataccag ttgtaccaga agtatgggtc
    67261 atataagaaa tttcattttt gtctaaaaat gattgagaaa cagacaaagc aggttgttcc
    67321 attaaataaa gaataggaat acccgtggtg ctagttaatt ttaatatcct aaagaatatc
    67381 tcaaagttcc ttcaaaacgt cgttgtgctc gacttaatag aacactgtaa gccagtaata
    67441 tgctttcaaa tctactctct agcc
//
LOCUS       DACDLM010000006        65412 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.006, whole genome shotgun sequence.
ACCESSION   DACDLM010000006 DACDLM010000000
VERSION     DACDLM010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 65412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65412
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.006"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            75..707
                     /locus_tag="IV356_000404"
     CDS             75..707
                     /locus_tag="IV356_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAP9014128.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            830..1468
                     /locus_tag="IV356_000405"
     CDS             830..1468
                     /locus_tag="IV356_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAP9014129.1"
                     /translation="MNNILGKKIELKKGILGTIVVVFGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(1587..1659)
                     /locus_tag="IV356_000406"
     tRNA            complement(1587..1659)
                     /locus_tag="IV356_000406"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1624..1626),aa:Thr,seq:cgt)
     gene            1780..2022
                     /locus_tag="IV356_000407"
     CDS             1780..2022
                     /locus_tag="IV356_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014130.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            complement(2161..2790)
                     /gene="upp"
                     /locus_tag="IV356_000408"
     CDS             complement(2161..2790)
                     /gene="upp"
                     /locus_tag="IV356_000408"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HAP9014131.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(2923..3870)
                     /locus_tag="IV356_000409"
     CDS             complement(2923..3870)
                     /locus_tag="IV356_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP9014132.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            complement(4023..5267)
                     /locus_tag="IV356_000410"
     CDS             complement(4023..5267)
                     /locus_tag="IV356_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HAP9014133.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            complement(5442..6467)
                     /locus_tag="IV356_000411"
     CDS             complement(5442..6467)
                     /locus_tag="IV356_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HAP9014134.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            complement(6489..6668)
                     /locus_tag="IV356_000412"
     CDS             complement(6489..6668)
                     /locus_tag="IV356_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014135.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            complement(6661..7500)
                     /gene="prmC"
                     /locus_tag="IV356_000413"
     CDS             complement(6661..7500)
                     /gene="prmC"
                     /locus_tag="IV356_000413"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HAP9014136.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            complement(7493..8566)
                     /gene="prfA"
                     /locus_tag="IV356_000414"
     CDS             complement(7493..8566)
                     /gene="prfA"
                     /locus_tag="IV356_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HAP9014137.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            complement(8569..9153)
                     /locus_tag="IV356_000415"
     CDS             complement(8569..9153)
                     /locus_tag="IV356_000415"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HAP9014138.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            complement(9259..9728)
                     /locus_tag="IV356_000416"
                     /pseudo
     CDS             complement(9259..9728)
                     /locus_tag="IV356_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            9834..10436
                     /locus_tag="IV356_000417"
     CDS             9834..10436
                     /locus_tag="IV356_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAP9014139.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            complement(10540..11109)
                     /gene="lepB"
                     /locus_tag="IV356_000418"
     CDS             complement(10540..11109)
                     /gene="lepB"
                     /locus_tag="IV356_000418"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAP9014140.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(11339..12106)
                     /locus_tag="IV356_000419"
     CDS             complement(11339..12106)
                     /locus_tag="IV356_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014141.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEELVVYSRSQRRRHS"
     gene            complement(12103..12582)
                     /locus_tag="IV356_000420"
     CDS             complement(12103..12582)
                     /locus_tag="IV356_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HAP9014142.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            complement(12707..13444)
                     /locus_tag="IV356_000421"
     CDS             complement(12707..13444)
                     /locus_tag="IV356_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HAP9014143.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            13605..15005
                     /locus_tag="IV356_000422"
     CDS             13605..15005
                     /locus_tag="IV356_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HAP9014144.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            15228..16580
                     /locus_tag="IV356_000423"
     CDS             15228..16580
                     /locus_tag="IV356_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HAP9014145.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            16573..17271
                     /locus_tag="IV356_000424"
     CDS             16573..17271
                     /locus_tag="IV356_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobyric acid synthase"
                     /protein_id="HAP9014146.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(17333..18484)
                     /locus_tag="IV356_000425"
     CDS             complement(17333..18484)
                     /locus_tag="IV356_000425"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HAP9014147.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(18497..18934)
                     /locus_tag="IV356_000426"
     CDS             complement(18497..18934)
                     /locus_tag="IV356_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP9014148.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            complement(18949..20715)
                     /locus_tag="IV356_000427"
     CDS             complement(18949..20715)
                     /locus_tag="IV356_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HAP9014149.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            20979..21656
                     /locus_tag="IV356_000428"
     CDS             20979..21656
                     /locus_tag="IV356_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9014150.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            21659..22786
                     /locus_tag="IV356_000429"
     CDS             21659..22786
                     /locus_tag="IV356_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9014151.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(22986..23426)
                     /locus_tag="IV356_000430"
     CDS             complement(22986..23426)
                     /locus_tag="IV356_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP9014152.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(23437..25470)
                     /locus_tag="IV356_000431"
     CDS             complement(23437..25470)
                     /locus_tag="IV356_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAP9014153.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            complement(25472..27175)
                     /locus_tag="IV356_000432"
     CDS             complement(25472..27175)
                     /locus_tag="IV356_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP9014154.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            complement(27269..28219)
                     /gene="manA"
                     /locus_tag="IV356_000433"
     CDS             complement(27269..28219)
                     /gene="manA"
                     /locus_tag="IV356_000433"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HAP9014155.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            complement(28258..29283)
                     /locus_tag="IV356_000434"
     CDS             complement(28258..29283)
                     /locus_tag="IV356_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAP9014156.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            complement(29492..30361)
                     /locus_tag="IV356_000435"
     CDS             complement(29492..30361)
                     /locus_tag="IV356_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HAP9014157.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            complement(31065..32957)
                     /locus_tag="IV356_000436"
     CDS             complement(31065..32957)
                     /locus_tag="IV356_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9014158.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(32954..34681)
                     /locus_tag="IV356_000437"
     CDS             complement(32954..34681)
                     /locus_tag="IV356_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9014159.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(34697..35347)
                     /locus_tag="IV356_000438"
     CDS             complement(34697..35347)
                     /locus_tag="IV356_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP9014160.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            35551..35847
                     /locus_tag="IV356_000439"
     CDS             35551..35847
                     /locus_tag="IV356_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAP9014161.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            36039..36659
                     /locus_tag="IV356_000440"
     CDS             36039..36659
                     /locus_tag="IV356_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HAP9014162.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(36751..37917)
                     /locus_tag="IV356_000441"
     CDS             complement(36751..37917)
                     /locus_tag="IV356_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP9014163.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(37929..38282)
                     /locus_tag="IV356_000442"
     CDS             complement(37929..38282)
                     /locus_tag="IV356_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAP9014164.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            38410..39432
                     /locus_tag="IV356_000443"
     CDS             38410..39432
                     /locus_tag="IV356_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HAP9014165.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            complement(39871..40305)
                     /locus_tag="IV356_000444"
     CDS             complement(39871..40305)
                     /locus_tag="IV356_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014166.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(40415..42274)
                     /locus_tag="IV356_000445"
     CDS             complement(40415..42274)
                     /locus_tag="IV356_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAP9014167.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(42392..43551)
                     /locus_tag="IV356_000446"
                     /pseudo
     CDS             complement(42392..43551)
                     /locus_tag="IV356_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
     gene            complement(43858..45282)
                     /gene="araA"
                     /locus_tag="IV356_000447"
     CDS             complement(43858..45282)
                     /gene="araA"
                     /locus_tag="IV356_000447"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HAP9014168.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(45298..45996)
                     /locus_tag="IV356_000448"
     CDS             complement(45298..45996)
                     /locus_tag="IV356_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAP9014169.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(45953..47614)
                     /locus_tag="IV356_000449"
     CDS             complement(45953..47614)
                     /locus_tag="IV356_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HAP9014170.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            47832..49232
                     /locus_tag="IV356_000450"
     CDS             47832..49232
                     /locus_tag="IV356_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HAP9014171.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(49484..50563)
                     /locus_tag="IV356_000451"
     CDS             complement(49484..50563)
                     /locus_tag="IV356_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP9014172.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(50649..51608)
                     /locus_tag="IV356_000452"
     CDS             complement(50649..51608)
                     /locus_tag="IV356_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HAP9014173.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(51620..53143)
                     /locus_tag="IV356_000453"
     CDS             complement(51620..53143)
                     /locus_tag="IV356_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAP9014174.1"
                     /translation="MDEEVKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHE
                     TADGDGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIE
                     PNSFGLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQ
                     KKPFGVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPR
                     LPSYPEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFD
                     RQIEEIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMED
                     TLLFGSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAK
                     GQVLKQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLL
                     DQGEHYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(53153..53716)
                     /locus_tag="IV356_000454"
     CDS             complement(53153..53716)
                     /locus_tag="IV356_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HAP9014175.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(53722..54585)
                     /locus_tag="IV356_000455"
     CDS             complement(53722..54585)
                     /locus_tag="IV356_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP9014176.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(54599..55495)
                     /locus_tag="IV356_000456"
     CDS             complement(54599..55495)
                     /locus_tag="IV356_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP9014177.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(55670..56941)
                     /locus_tag="IV356_000457"
     CDS             complement(55670..56941)
                     /locus_tag="IV356_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP9014178.1"
                     /translation="MKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTLTFWNGF
                     TASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFIALNYPD
                     FAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMYMYWNND
                     LFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLANGGKLV
                     NDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIEINGPWL
                     NNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFLKYWNTT
                     EIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQISAINNDI
                     INPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(56931..58448)
                     /locus_tag="IV356_000458"
     CDS             complement(56931..58448)
                     /locus_tag="IV356_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAP9014179.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            58646..59536
                     /locus_tag="IV356_000459"
     CDS             58646..59536
                     /locus_tag="IV356_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HAP9014180.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(59609..60433)
                     /gene="nadE"
                     /locus_tag="IV356_000460"
     CDS             complement(59609..60433)
                     /gene="nadE"
                     /locus_tag="IV356_000460"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HAP9014181.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(60445..61917)
                     /locus_tag="IV356_000461"
     CDS             complement(60445..61917)
                     /locus_tag="IV356_000461"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HAP9014182.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(62554..62916)
                     /locus_tag="IV356_000462"
     CDS             complement(62554..62916)
                     /locus_tag="IV356_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAP9014183.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            63139..63891
                     /locus_tag="IV356_000463"
     CDS             63139..63891
                     /locus_tag="IV356_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP9014184.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(64031..64954)
                     /locus_tag="IV356_000464"
     CDS             complement(64031..64954)
                     /locus_tag="IV356_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP9014185.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(64969..65241)
                     /locus_tag="IV356_000465"
     CDS             complement(64969..65241)
                     /locus_tag="IV356_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014186.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        18905 a        13410 c        11391 g        21706 t
ORIGIN      
        1 tatctcattt tctgctaatg taagttggtt tagcttttgt taatatgact ttatgaaaat
       61 ggaggtaatt aaatatgatt tttcctaaag ttaatgaagc aagcttgaat aaaggatcct
      121 tttttcatat ctatgaaaac gaagattttg aactgtataa tatcctttca caaaaagagg
      181 tcatcgaaaa ccaaataatc tgccatccaa ttatttacaa atctattttc aagtatgcat
      241 tttttgcttc caatgatttt caaagaatgg agattaccga ctgtatattc gaaaactgtg
      301 atttttcagg ctgtatattg acaaaaagca tgttgcatcg cgtgaaattt gtcaattgta
      361 aattaacagg tactaaattg atggaaagtt atattgggaa cacgttattc gagaattgta
      421 aaatggacta tgtaaattta tctggttcaa acataaaaga aagtaccttt gagcactctg
      481 tcttatcaag cgcagatttt gtagactgtt ccctcactaa aataatgttt tctactaatg
      541 atttagaaaa tgctagcttt tttgatactg atttaaaaaa tatcgattta agtagcaact
      601 cctttgaaat gattgaagta cgctcggaac atctaaaaaa ttgtacgctt aatcagttgc
      661 aagcacttgg ttttgctaga aaatttttac aaataaaagt agtataatca aaatgaatat
      721 ataagataaa tttttagcaa tacaaatatc cataaaaaaa cattgcctat tttaactctt
      781 catgtatact gactctatct tcaaaaactg aatagtagga gttattatca tgaataacat
      841 tttaggaaaa aaaatagaac ttaaaaaagg gatattgggc actattgtcg ttgtattcgg
      901 tttgttaggg ttgctatttg cgccatccat tattagcatt ttttctttaa ctatcactgg
      961 atttatagca tttacacttg tttttggtaa aaaagatacg aaaaaaatgt tctcgaaacc
     1021 tgtcgctcct gtcaaaaata tagccaaata tttttttatc aatgtagtaa tcagtgccgc
     1081 agtctcggta tttttgcaac aaattttgaa atggggttta acaggcaatc caataaatga
     1141 ggctttcagc ccgttattat ttattatttt gcctatcatg atacttggag aagaattgtt
     1201 ctcagtgtat tttctcgcta ttttttctag taagttcagc attcctgtcg ctagtttctt
     1261 gtcagcaatc atctttggat ttatccatta cagtacttat gataatggaa atattttaca
     1321 cactgtagca cacatccttt tgatacaagg ggtggcaaga ttgttattca accaagctgc
     1381 cattaaaagc aactcgatca ttacaagttg ggcagttcat gtgatatttg atttcacagc
     1441 tatattgcta gtcgttttat tctcctaaat ttttatagaa ataatacatg ctctattgct
     1501 aagaaagcat actttatttc ctttaaacaa aaagacagat gtatcaatgg attaaaaatc
     1561 cttgatatat ctgtcttctc ttttaatgcc agctataggg atcgaaccta cgacctacgc
     1621 gttacgagtg cgttgctcta ccaactgagc taagctggcc ttatccaaaa gaaattatat
     1681 actctatttg gctgattgta aagagtccga tggaaaatta gtttaatttc atgatatttt
     1741 tcataaaacg tggtataatt gatgtgaaag gcaggtttta tgaaaatggc aacttttgga
     1801 aaatttgata caactatcgt accatcggaa attggtgaaa aattcaagat caatactcac
     1861 gtaatgttca caattcacgg caagtcgcaa actggaacga tttcaaagca attgaaaaat
     1921 tccgctgttg ttgagattga tgaaactgca gaaaatgcga acttgatgac gcaaagtaag
     1981 ggtgtagtaa tcgttaacta caaagaacta aaaaagattt gaatttgacc atctctgcat
     2041 ttttgggatg gtttttttat atgcaaacga aagctgtgaa aaagctgttc tgcatcaaac
     2101 gttaaaaatg accaaaaaag gatgtgacaa aagttgtgtc acaccctttt tcgtatttac
     2161 ttattttgta ccaaacaaac ggtcacccgc atcccctagt ccaggaacga tataaccatg
     2221 ttcattcaat ttttcatcta gagaagctgt atagatgtca atatcaggat gcgcttcttg
     2281 caaagctttt actccctcag gtgctgctac caaacaaaca aatttaatgt tcgacgcgcc
     2341 acgttctttc aatgcatcga ttgccatgat tgctgatccg cctgttgcca acattggatc
     2401 tactacaaac aactgacgtg catcaatgtc ttctggaagt ttgacgaaat attcatgtgg
     2461 ttccaatgtt tcttcatctc gataaagacc gatatgtccc actttagcag ctggaatcaa
     2521 ttccaagata ccgtcaacca ttccaatacc tgcgcgcaag attggaataa tcgctacttt
     2581 tttaccagac aacgtttttt gtgttgtttc agtgatcggt gtttcgatca cgatgtcttc
     2641 caatggcata tcccgtgata cttcatatgc catcaacata gcgatttcat cgactacttc
     2701 acgaaaaacc tttgttccgc agtttttgtc ccgaataata gttagtttgt gttgaatcaa
     2761 tggatgatcg atcacttgaa atttgcccat tttttaagct ctcctttgtt ctgtcgtttc
     2821 tttttaattg taaaacaaaa tcaagtgatt gactagtcaa actcgccatt tttcctaaga
     2881 aaatccgttt ttgaaaagaa gtttcctgcg gacaagcaaa gcttattctt ttttcttgat
     2941 ccaagaagta gataatgcca ttgctgcacg cgttgccttt gtctgatcca tagcatttac
     3001 catgacaaaa tcatggatga ttccttggaa gcgtacttgt gtaacaggaa cccctgcatc
     3061 acgaagtttg cgcgcataag cctcaccttc atctcttaat acatccgctt ctcccgttaa
     3121 aatcattgct gaaggaagat catttagttc atttatattt gctctcaaag gcgaagctgt
     3181 gatttcagca cgctcttctt cattcgtcgt atattggtcc caaaaccaca tcattccttc
     3241 tcttgtcaaa aaatagtttt ctccgaattc atgataggaa tctgtatcaa aatcagcgtt
     3301 tgtgactgga taatacagca attgcttgga tattgggagg ccctttcgtt cttttgttaa
     3361 gatcgtcatg actgtagcca tgttaccacc tactgaatct cctgcaacga ttagattctc
     3421 gagatccaga ttttttgact tggctaattt attcagctgt tgcaacacag cataattttg
     3481 ttcaattgct gttggatatt ttgcttctgg tgatcgacta tattctggaa agacaacgac
     3541 ggaattcgta cgaaccgcaa gttctctgat caatttatca tgggtttgag cactgccaaa
     3601 aacccagcct gctccatgaa tataaaaaat aactggtaat ttatccatat tcccttctgg
     3661 tcgtacgaga cgaatattga gttttcccca ttcgccagta tccaccatca agtcttcaat
     3721 atcgacggaa tatttgttca caggtgattc ttgtacttct tctagtaaaa ctcttccttc
     3781 ttccggtgct agttcataga tacgcggatg aggcgcattt gcatcactga atgctactgc
     3841 ttccttttct aacgagatac gatcagtcat gacttttcct ccctgagatt tagtgtgaag
     3901 actaaaatta cacctcatat actagagagc atcaccgata ttgtcaaaga atccgttttc
     3961 ccaaaaaata aacagaaaag cccaacattg aacttttctg tttactaatg gaatttaaat
     4021 ttttattttt tatgcaacgg aaatttttca gttaattcgc gtacacctgt tttgacttcg
     4081 tctagttgag cgttatcatc ttttgcttgt aatgctttga caactagttc agccactttt
     4141 acagcatctt cttctttgaa cccgcgagta gtgattgctg gcgtgccgat tcgaataccg
     4201 cttgttttga atggacttag tgtttcaaaa ggaatcgagt ttttatttac agtgatattc
     4261 acactgtcca aaatgctctc tgcttctttt ccatttatac ctaactcgcg aacatcgatc
     4321 aacatcagat gattatctgt cgcccctgaa atgactctgg ttccaattgc ttgattgaaa
     4381 actttgacca ttgcttttgc attggcgatg atttgttcac tatattcttt aaatgcagga
     4441 tctaatgctt ctttgaatgc tactgcttta cccgcaatca catgctctag agggccgcct
     4501 tgaataccag gaaataccgc actatttatt ttttttgcta atgcttcatc gtttgtcaaa
     4561 atcatgccgc ctcgagggcc acgcaatgtt ttatgagtgg tagtcgttgt gatatctgca
     4621 taaggaactg gattaggatg aagtcctgct gctactaatc ctgcgatatg tgccatatct
     4681 accatcagtt ttgcgcctac ttcatctgcg atttctctga atttcgcaaa gtcgatcgtt
     4741 cgtccgtaag cactggcacc tgctacgatc aattttggtt gatgttttct agctaaaata
     4801 cgtaccacat tataatcaat aacttctgtt gtcggatcaa caccgtaagc aacaaagtga
     4861 taggttttgc cactgaagtt gactggtgat ccatgtgtta gatgtccgcc tgcggaaaga
     4921 tccattccta agatcgtgtc ccctggttct accaaagcga gataagcagc cgtgttggct
     4981 tgagagccgg agtgaggctg gacgttcgca aatttcgctc cgaataattc ttttgcacgg
     5041 tcaatcgcta aattttcaac gatatcgaca aattcacacc caccataata gcgatgccct
     5101 ggataacctt ctgcgtattt atttgtcaag atacttcctt gtgcagccat cactgcttcg
     5161 gagacaaagt tttcagaggc aatcagctcc aaattatgtt cttgtctttc ttcttctttg
     5221 gcgatcgcag cccaaagatc agggtcaaac gttttgtaat ctaccacaaa caacagctcc
     5281 tttttatttt cctacaattt tatttttccc atcaaaaaca aattgccaaa tattcgtatc
     5341 tcttctatta cgattagtta cgcttagttt ttcgttcact gatagaagat ttacttgata
     5401 gcattgtatc atactaaaag aatgcgacaa taaccaattg atcatttttc aaaataattt
     5461 tgtcctgctg cttttttcaa gcgattcatg taagcattcc ccaatccagt ttctggatac
     5521 acttgtacaa aaatcaaatc taatccaagt gttggttcat ctaatcctct tagacctgca
     5581 aacaatcctt tagccgccgc ttctactgag ttgtcgttat acatataaac agctgcagta
     5641 tctgtccgca cttgatccgc aatttcgggg cttgctatga cacctgcacg gatcttctta
     5701 ttttttgccc attgaactgc agttgaccaa tcgccatctc tgaccatcag aacacgtgta
     5761 tcgggtgagt agtgtttgta tttcatccca ggggcttttg gtgtttcatt ttcttttaca
     5821 agatgctgat caatagcaac aggagattcg atgactgctt cgatttgttc tttcgttact
     5881 gcacctggtc gtaaaatcat aggcatggct gttggatcac ttaaatcaag aacagtggat
     5941 tctacaccaa ttcgcgtagc tccatcatca ataatcccgg taatttttcc ttgtagatca
     6001 tgatatacat gatctgcagt cgttggactt ggttttcccg acgtatttgc acttggaccg
     6061 acaagcggaa caccggaaag ttcgattact tctagtgttt ttttgttatc cggtatacga
     6121 aatgcagctg tggataatcc tcccgtcaca actgagggca aagtgtcttt tttgatctta
     6181 aatatcaaag ttaatggtcc aggccagaag ttcttcacaa tcttctctgc tgccggatga
     6241 aagttgtcca catactcttt tacttgttca aaagaggcga catggacgat taatggatta
     6301 tcttgcggtc tcccttttac agaaaacact ttcttgacag cgtttggtaa aagagcgttg
     6361 gcgcccaatc cgtatactgt ttcggtagga aaagcaacaa gttctccttc tttcagtgct
     6421 tcggctgcct cttgcaattc tgtttcatca tatcgtttcg tttccacagt ttatccacaa
     6481 cccctttttc atacattctt attttgtctg agtttatcct caagttttcc actgtttgtg
     6541 gataatctat ttgtcaatag tggataaact tgttgataaa ccaaaaagtc gtttacatcc
     6601 ttgtcaaata agtgtttttt tataataaaa aaacaaataa aaaatttttc atccacaact
     6661 tcaaccataa acttggatca ttcgttcatt gccaaaaaga tcctttttta tcgccacttt
     6721 tttatctgga aatgcttgct gaaatatttt ttttactgct tcaccttggc gaaatccgat
     6781 ttctaaaaaa atctttccat ttgattttag tacgcttggt gcttcaactg ctattttttc
     6841 ataaatagct aatccatcgt tctcagcaaa aagggccatt ttaggttcga atgaccggac
     6901 actttcatcc atcagttccc attcattccg actgatgtac ggcggattag aaataatcac
     6961 atcaaattgc tgatccatta ctggtcctaa tgtatctcca tgataaaaac tgattttcgt
     7021 tccttctttc tgagcatttt ctttcgctac ttctaatgct tcttctgaaa gatccacagc
     7081 agatatatgc caattttttc ttgctgcttt caaactaata gcaattgctc cagtccctgt
     7141 cccaatatct atcacttcta acggtacacc aggcgtctcg tctaaacacc attcgactaa
     7201 ctcctctgtt tctggtcgag ggatcagtgt tgcttcagtt acctttaacc gatgatcata
     7261 aaaatctgca tatcctagca aatactgagg tggatgatct gcaagcagaa gtcgcagatc
     7321 ggtttcgatc aaccgctgtt cttcttctga aatctcttcg ttcatatgaa ggagccaatc
     7381 aagttttttc cattgttttc gttccaaaaa taaaaattgg atactatatg cttctttccc
     7441 atgatcctct aaaaaagaag aagcccgtga caggacttct cgataggtca ttttacccat
     7501 tttgcatagc ttccagtttt gatgtttgat catacatgat caatgcatca acgatctcat
     7561 ctaatttccc tgctaaaatc tgatctaatt tttggatagt taatccgata cgatgatcag
     7621 tcacacgatt ttgcgggaaa ttatacgtcc ggatccgttc tgaacgatcc ccagttccga
     7681 ctgctgattt tcgattggca tcatactcgc tttgtgcttc ttgctggatc ttatcgtaca
     7741 cacgagcacg caagattttc attgcttttt cacggttctt gatttgagaa cgttcatctt
     7801 gcatagcaac aacgatccct gttggtaagt gagtcaaacg tacagcagat gctgttttat
     7861 tgacgtgctg tccgccagca cctgaagcat gatagatatc tgtacggata tctttgtctt
     7921 caatatcgat ctctacttct tcagcttctg gcatcacgac aactgttgcg gtggaagtat
     7981 ggatacgccc ttgcgattca gttgaaggaa cacgctggac gcggtgcgca ccactttcat
     8041 attttaattt cgaatatacg ttgtctccgg tgatcatcat gatcacttct ttatatccac
     8101 cgattccggt aacgttagct tccatcactt ctgttttcca gccttgtgct tcagcatact
     8161 tttggtacat attgaaaaga tcgccagcga ataatgctgc ttcgtctccg cctgctgctc
     8221 cacggatttc catgatgata tttttatcgt catttggatc ttttggtaaa agcaagatct
     8281 tgattttttc ttctaagact tctttttctt tttttaattc agataattct tcttttgcta
     8341 gttcagccat ttcatcatcc agtttttcac caagcagttc ttctgtatcg gtgattcctt
     8401 gtactacttc tttataacga cgataaactt cgactgtttc gcgcgtgttt gcttcttctt
     8461 ttgaaagctg cataaaacgc tttgtatcag aaatcacttc tgggtcactt aaaagttctc
     8521 caagctcttc ataacggtct tcaattgctt gtaattgatc gtacatgctt attctccttc
     8581 tgtaatcatt gatgggtgaa agtaatgttt tcgacaaacg gggtaataag cttcatttcc
     8641 gccaatttgc acttgatcgc cttcataaac agggtttcca tcaatataat gtaaattcat
     8701 gattgctttt ttgtggcaga accaacagat tgttttcatt tcttcgattt tgtctgcata
     8761 aagcaataaa tattttgatc cttcaaataa ctcgtttcga aaatcatttt tcaaaccaaa
     8821 tgccataacc ggaatatcca attcgtccac aattctcgta aaagcaatga catgtttctt
     8881 ttttaagaat tgcgcttcat cgatcagcac acaatagggt ttgctttcca ttttctgaat
     8941 tacgtcaaat acgtctgttt cttcaaatat cggcatcgca ttacgtttca gtccgattcg
     9001 gcttgaaaca acgcctaaac catctcttgt atcaataccg cttgtcatta agacaactgg
     9061 cttattttgt tcttcataat tatgtgcgac ttttaggatc tcgatcgtct tgccgctatt
     9121 cattgcgcca tacttaaaaa atagttgtgc catgctcttt ttcaccttcc agtttgttcc
     9181 tatggtatta tacttgattt tcagcatttt ttacagtgag aattttcatc aagcacagat
     9241 tagtattaaa tctattgctc acttttgttc caattttttg acaagaacta aacatgggtt
     9301 ccattcatcc cataaatttg gaaaaacttc caaccttgaa aatcctaatg attcgtagaa
     9361 acaaatagtt tgatcatata tagagtagtg cccctcgtct acagtcttca cttgcaaata
     9421 tttgtaatgt tttgctgcgt aaccttctgc ttctttaaaa agttttgttc ctaatccttg
     9481 gtgatgatag tcttttttta ttcccataca atagaataga tttcggcagt atcttcactt
     9541 gtctgtgaaa gagtgataaa gcctaaatat tcttcttttc ttttttcaca ccataaaggt
     9601 agtttacttg attcctcgat atatttttcc gttgattcag gaagcccaaa ccactcaggc
     9661 aagtctagta atatttctcg gacacacttt cctttttcct ctctatcttt tacaaacgat
     9721 atcggcatat tctttctaga ttctcccttt ttgaattgag tatagcatgc tttctttctt
     9781 ttcacgtgct ataataagtt aaaatttcaa agttttacgt aaggagctat ttgatgacaa
     9841 aaaatatttt tgattccatc gctaaccatt atgattcccc tgaccgtcaa gcattagcca
     9901 agattattcg cgaagaacta actacttatc taccgcgcga cagccaccaa aaagtcctgc
     9961 tggattacgg aggcggaact gggcttgtta gtttaccgct tgcggaaaga ttcaaagaac
    10021 tgatcattgc cgatgcttca gaaactatgc tgaaaatggc agaagaaaag atccaagcag
    10081 cagatctgaa aaatgtccga acgatccacg ctgatgcttc tgtcgaattt cctgctgtcc
    10141 aagctaatct catccttcta tcacttgtac ttttacacat tcctgatacg gagaatattc
    10201 ttacaaaact ttatgaaatt ttagctcctg gcggtcaatt gatcatcgta gactttgaca
    10261 agaatgaaca aattagtcat ccgaaagtcc ataatggctt tagccaagaa gaattgaata
    10321 atcgattgga aaaaacgggc tttgtctctg ctactagtca taccttccat cgtggggaaa
    10381 agctatttat gaacaaaaac gcttcgcttt tcttatccat cagccaaaaa gcttaaaatg
    10441 agattgcaaa aaaagtgagc aactccaaga aataagaagg aattttcgga aaaagaagct
    10501 gtgacaaaaa acatgtcaca gcttcttttt attttttcat cacatgattt taatttctga
    10561 aagaggccaa taacggaaaa caacttttcc ttggatcata tctttgtcga ctaacccaaa
    10621 cattcggctg tcttttgaaa tcaagcggtt atcgcctaga acaagatact ttccttttgg
    10681 cacagtatat tcaaagtcac tcgtaaaggt ggatgaactt tctgcttgtg cttggaatcc
    10741 tgagctataa gcatattctc cttgtaactt atcttctgaa aattcttttt tgaactcatc
    10801 cagataaggt tcatcatact ttttgccatt aatggtcaac tggtcatttt ccatcttgac
    10861 tgtatctcca ggcataccga tgatccgttt aacaatcatc cgttcttcat cccccggttc
    10921 ctttgtagta ataatatcca ttcgttcata gtttgagatc ttagatgaaa tcaatcgttg
    10981 tccatcactt aatgtagggt ccatcgaatg cccgtttaca gtaactggtg taaacacgta
    11041 cactctagct aataaaatag ccgctaatac aaggatcaaa atcccccaat ttttcaaaaa
    11101 ttctttcaca gcttacctcc tacttgtatt ttcctcgtta tttattacgt tttttcacaa
    11161 tacttcgttg tactttcttt attctacaat gtttataaat gaaaggaaag aataagtgat
    11221 gtgttcgtct tatctttctc gttatataaa aaaggaacgt gacaaaagac gtgtcacatc
    11281 ccccttattc cgaataaacg tttttatcgc aaccactgat acacggcgtt tcatcacatt
    11341 atgaatgtct tcttctttgg ctacgactat aaaccactag ttcttcctgc gactgtgcct
    11401 tttttgcaat caatttcaga cgataaggct catgatagcg taacccgtct ttgacaaaat
    11461 caccgccgac gatgaacaat ccgacaggtt ccaatgtgtc ttctgttgag tcaagtcgaa
    11521 tggtccctac tttttccatg tccgagtagc ttcgtccaat atttagaaca tactctttct
    11581 ctcctgtttt cttgacatag taataaggat acaatgtatt tctatcgacc agaaatccat
    11641 ccatgcgacc gagttcattt gttttgatct caccatttcc aatcaaatac cgcatattct
    11701 cggctaattt caattgataa tcttcgtcat aagaaaccat gacctcttgt gtattcactt
    11761 tatcgatcga atttccatta tctatcgatt cttctgtctg gatgttgaac gcttcatcag
    11821 gtaaatactt cacaaaaagc tgagtgacat cggctttcgt gtttttatct aaaaagtaat
    11881 aaaatacatt taaaacagta aaataaacaa gcactagaaa tgcaagtcca tataagaaaa
    11941 attgaagata gttttggttt tgccaaagtc cataaacaat tctcaataaa taaagcgtgg
    12001 gaatcacact taaaatcgta tatccacggt taagatattt aggactgatg tctaaatagc
    12061 caaggaattt atgcaccccg ttgataaggt ctagtaaaaa tgtcattgag aatcacctgc
    12121 ttgctggtta tacgtttggg tatttcctga atcttggttt tgctgtgctg tacgtgctgc
    12181 atcatcattt tgcgtgttat catctacagt cgtactgctt ggtatcgttt cggagctagc
    12241 acttgtatcc ggacttgtac ttggattggt tgaatccgat ggagtgccat ctggtaccgt
    12301 attacttgtt tcgcttgagc tgtcagttgt atatgtctca tcatacgacg aactagttgt
    12361 tgtatcgtcc catgtacttg tcgtagtggt ttcattcaaa ctttccgttg ttgttggttc
    12421 agatgtcgag actgaagtag ttggtgttgt ttcttctaca gtactagaac ttgaacttgg
    12481 tgcacggtag ctggaactat tcacaatacc tgtagtagtc gcgacaatcg tcgagattgt
    12541 taatacagcg attggcttca aaataggtgc tacttttcgc atcttatctc ttccttcatt
    12601 gaaatttatt cttgtttcct tactttacta cggacaaatt atacagtcta ccttatttct
    12661 accataaatt ctttattttt ttcttacgtt tttccgaaag atttctttaa ttttcctcaa
    12721 aaactacggt tgatgttttt aagtaagctt ttgcttcccg attgatttct ttcagatcgc
    12781 atccttgctg cttggcagcg aacacgcaac cacaataaca ttggcgataa atatcatact
    12841 ctttgcacat ttgcaaagag cgttcatagc ctttgttttt cttgaaatca cttggcaagt
    12901 attgtgtccc gtaaatcttt tggatatcca ttccgatctg attgatcaaa gctgcatttt
    12961 tctttggcga gatggtcagg gcacttccaa agtaatcgta tcctagttct tgcgcttttt
    13021 gcgcaacaag atctaatcgc atattgaagc atgcactgca gcgagcacca ccttcttttt
    13081 cgttttcaag atggtttgtt aaaaccattt tggtgaattc atttggacgg tattcatcaa
    13141 cgattagcgc aacatgatgg tcagttttct cattaaattg gtctacaaat cgtttttgtt
    13201 catgtaatct tcgcaaatac tcacttttag gatgaatatt cgaatttgaa aaaaataacg
    13261 tgatctctgc atattgagac atgaattcca atgtgtgcgt actgcaagga gcacagcatg
    13321 tatgtattaa tatcttaggc tttacttctt ctttctccca ttgcatgatc atttttttca
    13381 gaactgtatc ataatttatt ttttgatttt tcattttttc tacgatttgt tgagcattaa
    13441 tcaatttgtt attcctcctc cttctttttt ctaggatttt ccttattata agccatttct
    13501 attttaatcg aaagctgtat tgttatctgt ttgataattt ctttgagtat tcctaattcc
    13561 ccttgtatac tggtagaaac gactattgtc aggaggatag tactgtgcat gttgatttat
    13621 tctttcgaag gctgcagcgg cgaggacaga agtttgctgc caatcatttc tcatcgatcc
    13681 aaatcatcgt tttttattat atattgatga cggtcttatc actcgttcta ttttatatgc
    13741 cgatttttcg cgaaccagat agccatgttt cttttgtgga catgctgttc atggcaatca
    13801 gtacagtgag tgtgactgga ctatcgactt ttgatatcaa ttctgtgttc aatgataacg
    13861 gtattatact gctggaaata ttatttcaag ttggtggttt ggggatcatg atgatttcta
    13921 ctgcttttgt cattttttct aaacgacgga tcacactgaa acagcgacag ctgatcatga
    13981 cggatatgaa tcaaccgcgt ttgtctggta tcgtccgact gattcggatc acttttgcta
    14041 ttttaatctg gtttcaatta ctttttggga cattcttttc tatttatttt tattacagag
    14101 gctattttga tcgttggcgt gatgccgttt tttacggttt ttatcaggcg atatcggctg
    14161 tcacgaactc tgggtttgac gtcactgggg attccatcaa gccctttgca catgactatt
    14221 ttttcttgat cctgatcatg tttttgattt ttgtcggagg aattggtttt cctgtattga
    14281 tggagtgccg ggaatggcta ttatacaaac gttccaatgc gaagcttccg tttcgttttt
    14341 ccttgtttac caaattagct gtgttagctt ttgttatctt gtttgtttcg ggaactgtct
    14401 tgatttatct attggaaaag gaccatttat tccaagattc caatatgagt gtcaaatgga
    14461 tcaattcgat gttttattcg attacgactc gtaatgctgg tctgcagatt cacgatttgg
    14521 gtgattttca aatcacaaca ctgatcattt tttctttact gatgtttatc ggatgcagtc
    14581 ctagttctgt aggcggcggg attcgaacaa ctactgtagc aatcatcggt ttgtatctat
    14641 attccttcct caaaagtgaa gataacatca atatttttgg acggagaatc gatcaagatg
    14701 atgtgcgaaa atcagtcgtt gtctttatgc tttctcttgg tatgtgtttc ttttgtatcg
    14761 tttttttatc tgctacagaa gaacaaacgc tgatctcgat catcatcgaa gtaacttctg
    14821 cgtttggaac aactggttta tctttaggga ttaccggaga cttgtctgtt gtgggcaaaa
    14881 tcacgattgc tacactgatg tttattgggc ggatcggaat gctatataca ttgatgttat
    14941 tcgtgccaaa agaaacacga gatctaggct atgaatatcc aagcgagaaa attattatcg
    15001 gttaaaatgg gaatataggt aagagggaat aataaaatca cagcagcttg aaacaatcat
    15061 tttgtttcaa gctgtttttt tgttaaatca tgcgattttg tccgatttca tgcactttca
    15121 gccgtaacct tttcttaaga ataagaaaag caatttaacc tttttttcaa catatggtat
    15181 gattagttga atttattcgt cagcaaatcg tttttggagg ttacataatg ggaatacgca
    15241 gtcattttgc gattgcagtt ggaaaaacgt cgcaatgggc attaaaaact ttttttaaag
    15301 gcggatcaag tttaccaggt aaactagcgc tgaaagtcga tccacatata ctagatagtt
    15361 tggcaaaaga ctaccaagtc gtcgttgtca ccggaacaaa cggtaaaaca ttgactaccg
    15421 ctttaacagt caatattttg cgccagcaat tcgatgaagt tctaaccaac cctactggtg
    15481 cgaatatggt acagggaatt gtatcgactt tcttgcaggc aaaaccaaaa aaaggacaga
    15541 aaaagtttgc tgtcctagaa atagatgaag caagtttgag caaagtcaca gaatatatga
    15601 aaccagaact gttcttattt acaaatattt tccgtgatca aatggatcgg tatggagaaa
    15661 tctatacgac ctataaaatg attgtagacg gtgccgcaaa gtcaccaaat gcaacgatta
    15721 tcagtaacgg tgattcacca atcttcaatt ctatcgaaac agtcaatcct agaaaatatt
    15781 atggctttga ccatgaagaa gatcgtgaac aaatggctca ttacaataca gacggtgtct
    15841 tatgtccaaa ttgtcatcac atcttgcatt ataaaatgat cacttatgca aacttaggga
    15901 aatattactg tccaaattgt gacttcaaac gtcctgaatt ggattatcga ttaactgata
    15961 tggtacggat ggacaatgtg tcagcagatt tcgtgatcga tggtcatgaa tacggaatcg
    16021 aagttggcgg tatgtataat gtctacaatg ctttagcagc tactgcagtg gcagagtact
    16081 tcaatgtcga tcctgataaa atcaaacaag gtttaggata tgacgagaaa gtattcggcc
    16141 gacaagaagt catcaatatc aatgggaaaa aatgtacatt agtacttgtc aaaaatcctg
    16201 taggtatcaa tcaagtaatc gatatgattg gtctagctcc ttatccattt tctttagtgg
    16261 ctttattaaa tgccaattac gcagacggaa tcgatgtcag ctggatttgg gatggtaatt
    16321 ttgaaaactt tgccgatatg gatatcccag ctgttatttc tggaggagac cgtcatacag
    16381 atatgacttt acgtctaaaa gttgccggga ttccagaaaa taaattgaca gaaacaaaag
    16441 aattaccaga agtaatcgaa aaaatcaaag aattgccaac tgagcatgtc tatattttag
    16501 ctacttacac tgctgtattg cagcttcgta aagaactagc tgctcaagga tttatcaaag
    16561 gaggaatgaa ccgtggctaa ttatgaactc aatatcgccc acctttatgg aaatttgatg
    16621 aacacatatg gtgataacgg aaaccttttg atgttgaaat atatagcaga aaaaatgggg
    16681 gtttcttgcc atacggagat cgttagtata catgaacctt ttgatgctga taaatatgac
    16741 ttggttttct ttggcggtgg tcaagacttt gagcaattaa tcatttcaaa agacatccag
    16801 aaaaagaaag attctttgat caactatatc gaaaatgatg gcgtcatgtt agccatttgt
    16861 ggtggctacc aattgctagg tcactactac atgggagcta atggagaaaa gatccaagga
    16921 atcagtgcac tggatcacta cacgttaagt caggaaaata accggtttat cggtgatatc
    16981 gttatccata acgaagaatt caatgaaact tattatggat ttgaaaacca caatggtcgg
    17041 actttcttag gtgaaggtga acgacctttg gggaaagtgg tacaaggtca aggaaataat
    17101 ggtgaagacc aatctgaagg tgtcatttac cgaaatgtct tcggttctta tttccatgga
    17161 cctatccttg caagaaatga gaacctggca gctcgtttga tccgcctagc tttagaacaa
    17221 cgttacggta aagaattgga tctgccctat cttgaaggac aaacagccta gttattcgaa
    17281 aaaggggaat gtgacaaaaa tttcgtcaca ttcccctttt tcgtatccta ttttaagcga
    17341 cttgcttggc ataacggttc acgttttgct tgatattccc gattgttttc ggatcattga
    17401 ttcctgtgac ttcttgaatc aattgttcca agttttcatg gatcttcatt tcatgcaatt
    17461 gacggctttg ttcatcttca ggatcatagt aattaaaaat aatccccatt gttgccgtca
    17521 aatgtgggca agtcaagtta tgttcttgta gttctctcac tggacgtgta aatctttctt
    17581 gataacctaa cttacgtaat ggtgtccgag cgacacgtgt gatcgcatca gagatatttt
    17641 tgttttggaa gcgatgaatg attttttcaa tatacgcatg atgctgctct gcatcaaacc
    17701 cccatttggc aatcagcaaa cttcctgttt cctgcaaaac tgattttaat tgtgccacaa
    17761 ctaacgcatc ttgcattgct tcatcaatgg tctggtaacc taacaaggca cctgtataag
    17821 cgacagtcgc atgaccagta ttgacactaa atagtttgcg ttcgatatat ggttctagat
    17881 catctacata taaaacccct tttaattgga tttttttatt ttttctttgg ctatcgtcaa
    17941 tgacccattc tttgaaaggt tccacttgga cgaataaagg atcttcatgg tgttgtaatg
    18001 ggacgattcg atcgactgct gcatttggaa agccgatata tttgtcagta aatgatgttt
    18061 ccggaagata tttatacact tctttttcta gaaatgctga accgccaatc atattttcac
    18121 aggcaatgat atctaaagat gttgtgcttc cttccttttc tctttcttgg ataccttttg
    18181 caatcaactc agcaataaaa ggtaagatat tcgggccaat ggcggtagta actaaatctg
    18241 cttcagcgat ttcttggatt actttttctg gatttgtttg attgttgatt cctttgacat
    18301 tttttacagt gattttttct tttgattcat ctgctaattc gatttcgtat tcttttcttt
    18361 catttaaagc atcaatgatc gtgtgattca catctacgaa agtaatctca aatccattag
    18421 ctgccaaaac ctctccaata aatcctcgac cgatatttcc tgcaccaaaa tgtactgctc
    18481 tcatttttct ctctccttaa gcaattgcta gattttccgt tacttcttct ttgctgagcg
    18541 cgtctgctag ctggacaaca ttgtccatat cactgcaata aagtgcgatt tgctgtacaa
    18601 gttgcaaatg ctcatctccg actcctgcaa taccgaacaa aacagtcgca atcttttctt
    18661 cttcttcggt accaaaatct acaccatctg gtacttgaac gacacagatg ccggattttt
    18721 tcacatattt ttttgcttca tctgttccat gaggaatcgc gataaaattc cccatataaa
    18781 cagataacat tttgtctcta tctaccatgg catcgatata ttcctcatca acgcaccctg
    18841 cttctacaag catctgaccg caatagcgga tcgcttcttc tttggtttta aaagatcgat
    18901 tgagctcgat catgtcgaat ggcaaacttt gcatgctgtt ttcctccctt aagctgtctg
    18961 tttcaaatat tgtgcaatcg attcgtattt ttgcggattg accatgctgt tgactgataa
    19021 atgaatggat tgaggtgcag ccatctgtac tttttccgct aaactttctt tggctacgat
    19081 cagtgaatca ggttcatctt ttaaatcttg gatattgact tttcttaacg ggatagttaa
    19141 atggttcttg tctaatatat ctttgagcac ggtcatcccc attgttgctg atccggaacg
    19201 atcatcgtgg acaagtagaa tctctttgat ttgtttgatg tttgctgaaa gaaactcttc
    19261 tgctggctca ttctcaattt cagaaactga tgttttctgc ttgctgctta attcttgaat
    19321 gatttcatca tatcgaggtg aattcaaaaa gttttctact gagacaaaac gcgcgctcgg
    19381 tgctttttgt tttgctcttt cttgtagttc gacctgagta acgatcaatg tattcgagtc
    19441 atctgtcagt tggctgattg cttgattggt caccgtttga ggcaagtctg cttcctgtac
    19501 tttttttctc aagatcgaag cgcccatcgc acttgatccc attcctgcat cacaagcaaa
    19561 aatgattttt tgtacgccag agaatgtagc tccttgagga ataccttggg cacctttgga
    19621 agcttgctta gctgcctttg tctcttgaac agatttttcg aagtcttcat ttgtatcttt
    19681 cgcatccgct ttcaaaatta ctgcagaaat accaaacgaa acagctgcgg caacaatcac
    19741 gcccaaaata acaggaaggt aagaattgaa cggtgtcatc gctagaatcg caatgatcga
    19801 ccctggagaa gctggcgctc ttagtccagc atccatcaat tggaaaatga aacttcctga
    19861 cattcctccg cctataactg ataagaataa taacggtttc atcataacgt aaggaaaata
    19921 gatttcatgg atcccgccta aaaagtgaat gatcatggct cctggtgctg aagattttgc
    19981 tgctcctttg ccaaacaaag taaaagcaag taatacgcca agtcctggac caggatttgc
    20041 ttcaagcaag aatagaatag attttccagc ctctgctact tgttcagttc ccaatggtgt
    20101 caaaatccca tgattgattg cattattcaa aaataagatt tttgctggtt caataaaaat
    20161 acttgtcaat ggaatcaaat gggcagataa aatgatctct acaccttttg ccattgcttg
    20221 agtcaatgca tcgacaactg gaccaatcgc agaaaaacct aataacgcta atccaaaacc
    20281 gataagacct gctgaaaaat tattgactag catttcaaaa ccggatttga tccgtttttg
    20341 gaatagctga tcaaatttct tgatggcata tccaccaaga ggtcccatga tcatcgcgcc
    20401 tagcatcatt ggaatatctg ttccgacaat cacacccatc gttgcaattg ccccaacaac
    20461 tgatccgcgg tcaccagcaa ttacttttcc gccagtataa ccgatcaata aaggaatcag
    20521 ataagttagc attgggctta ccatggtagc gaaagcctca tttggtaaat aaccatctgg
    20581 gataaataga gccgttaata caccccaggc aatcagtgct ccaatatttg gcatgaccat
    20641 gcttgataaa gtactgccta atttttgtac cctcgctttt agcgaaatgt tgtttttggg
    20701 aatcgtccgt tccattttgt ctctccctct ctccttttga tactctaatt gtatccgctt
    20761 actaaaaaga gaaatagtcg tactttggca cgaaactttg tgccaaaggt ttgagtatgt
    20821 cagcaaaata aaaagatttc ggtatcagaa aacttcaatt ttaaataaaa ctgttatttt
    20881 aattttttta taatatgcaa acaataactt ttgttagcat ttaatttaga tgttttccat
    20941 tctattatgt tattaaattt tatattggag gcctatctat gacattactg atcaaaaaca
    21001 tgaacatgaa acgtggtaaa aaacgtgtga ttcgacaatt gaatctttta gtagaatcag
    21061 gagaagtagc tgctttgatt gccccgaacg gatttggcaa aacaactttg ctgaatggca
    21121 ttgcccaact gctgccaaca acttatgatc aattgtccct tcacaacatc tctcctactg
    21181 cttatacaga ttatcgccgg tctttctttt ttctagaatc aacgaatcag ttatccgact
    21241 atctatcggc tgttgattat ttgactttga tcaaatacta ttggcagagc aaagtagaat
    21301 gccaaactgt tttccaacga ttgaagatga ctgagtacct tactttgccg attggaaaaa
    21361 tgtctctagg aatgaaacaa catgtcttgc ttgctgctta cttgatcagt gattcatctg
    21421 tcatgttatt cgatgaaccg ttgaacggat tagacccagg aagtattgat atcttgaata
    21481 gcctcatcag acaatggcag aaagagggga agacgattct tctttcttcc cacgctatcg
    21541 cgaatatcca atcgatttgt tctaaagcat gttttctaaa aaatggagaa atcgtcacag
    21601 aatcctcaaa tatggaagag attttagcta tttatcgtaa attatatgag gtgtaactat
    21661 gtctttactt acatttgaac gcaatctctt actaaaaaac aaagtaaact ttttatttcc
    21721 tctattgttg gtcgtgctct ttgcattccc actttttttt gatcataaac ttgcttatac
    21781 agaattcgat gaactgaatc ataactatga agagatgcaa cgtttgattg aaacgttgaa
    21841 agaagatgag aatgagaaag aatttgtgga aagtttagag aaaagcaaca aactgatcga
    21901 agcaatctta catgcaaaaa acacagggaa tgtccagcaa atggtcgaag caacttatca
    21961 ttatgaaaaa gatatactgg atcgactgat ttctggtcaa agacaaggaa ttccaatcat
    22021 tgaacaacaa aaacgtgtcg agttgctccg ttatatgaaa gaacatcaga tccaaagata
    22081 ttctattttt gacttgccag cgcatctctc tttagcaaat tactacgaaa atattttttc
    22141 aggaatgatt tctagttttt tgattttatg tataaccgcc ttgtttcttt cttccatcat
    22201 ctcttatgaa aaaagaaagc aggtaatctc tctagtcaat ctattaccgg atagtatggt
    22261 aaagaaacat agcatccgtt ttaccattta ttatggtgca gctatgctaa gtctcgtgat
    22321 gccatttttg atcgtctcta tactagtaat aatcaaaaat ggtttgggag acttccgtta
    22381 tcctgtagga acgatcattg gtcaggagat acgaatcctg ccgatgtatg agtatctttt
    22441 ccagagcttt ctgttcctgt tgttgtgggt gctcttttta agtacaatca gttttcttct
    22501 atctgcttta tttgaacatt ctctagtcaa tcttttaggt acacttcttt gtcttttctt
    22561 agcagagtat cgcttgtttt cttcgattgg atggatagaa tcaatcagtc attacttgcc
    22621 aacttcttat gttgattttc aaaatgtgat cataggagga gatattttct cgccactagc
    22681 ttcagaacag gttactttca tgaatggtat cttgacactt ggtatatgga gtatcgtttt
    22741 attattcata ggtatgggca ctatctatat aaaaaagagc tattaaaaca caaaaataat
    22801 aggggcggtg acaaaaacct tgtcaccgtc ccctatttca aataaacggt tttctagaat
    22861 aaatagtttt caaaagcttg catccgcagt aataagaacc tcccaacaaa aatagctcct
    22921 cttattttta tcttggttga agttattact tgatgcaagg cagctttttt tactgtgaac
    22981 attggttata tatgtccatg ttcaaaaatc atttggactt cttcaatggt ttccgcatca
    23041 ctgagcgcca ttacttggtc gatgtctgaa cagaaaaagg ctaaatcttg gagcaccgct
    23101 aactgatgtt ctttttttaa agccactaca aataagagtg tcgcgatttt tggttcctct
    23161 tttgttccaa agtccacacc atcaggcact tggactaaat agattccttc ttctactact
    23221 tcttcatctt tgtcagtccc atgtggcaag gctacgaaat tcccgatata gacactcgct
    23281 ttttcttgtc tttcgatcat tgattggata tatgccggtt tgattccccc ttgttgggtc
    23341 atccactggc cgatctcggt caacgcttct ttccaatttt gataggattg atcgagcaat
    23401 attttttctg ctggtagctg tatcatcttt tcaccttcat ttctttattt cttcaatcag
    23461 gattttcgct aacaactgat aaacgatttc tttatttcct gagcggaaga tctcggtgtt
    23521 caagtcattc atgatgattg ctccactgat ctttcctaaa agaatcccgt ctttttcttg
    23581 gattggcgaa ggcgccagca taactaacat acgggacaaa tcgactggct gtctatccat
    23641 cccttcaatg gtcaacggat gtttcaaatt gaaaatacaa aagatcggtt tagaaatcaa
    23701 tgagctggat gtatggaata accccatatt tgtatgagga ataccgatag gtgcttgttc
    23761 atatcgctta agcagccggc gatgaaccac ctcttcatcc gttactagtc cttcaggaaa
    23821 ataaggaaat aagctgcgaa tcgtttcgga aatcgtctca ggattatcca gttcttggat
    23881 aaaaaaacga ccgagtaatt gattgatttg atccatgaaa tgcattgttt cctcataagt
    23941 atcttctatc atccactcgt tattgctgtt atacgtaatt ttttgccttt ttttcttctc
    24001 aatatgcgaa aaagcttctt ttagctgctt gacttcatct tctagcagta gcggggagac
    24061 taaaatatat tttccaccgt atcctggtaa aatagatgta gaaataacaa catcatattc
    24121 ttcttgtaaa tcgatttttt ttaaatcagc aatccgatag aaatgaattt gttggatgaa
    24181 gggaaaatac cttttcaatc gtagttccaa catgctagta gaagctaatc cacttggcga
    24241 aaatcctgca atactgatat tgctttcttt cggacttcgt tccaatgaat tcgcaaaatg
    24301 aaggaccata taagcgatct cttcttcgga taattttttt tcttgaaaaa tccgctctac
    24361 tgctttacgg attgcattcg caacttcctc gtattgaacc atgatttttt ctaaaatcgg
    24421 attggtcagt gtctcttctt gtaaaacggc tcttgaaaac acaccagata aatgagtcaa
    24481 cagcattttg tacaaagttt catcttcata aaaatggaca ttcgtctctt cacttacttc
    24541 ttgaatcagt tgttttacta aataagcaag ctgtgtatcg aacgtctctt caaagaaatt
    24601 ctgatcaaat gagttcgtga agtcatttaa taatcctgca aaaaagacga tctcatttac
    24661 tggataaagt tgttttgtct cagaagcgat ccgtgaaaac aatcgtttag ctgtctgtag
    24721 taattctttg tttgccagac tattatatgt ctcatttgtc agtaaatgat ttttcgtcac
    24781 acgctccatc gtcaatgtca gcatcaaaac caaatgttca agctttctat cacttagatt
    24841 ggtctttttt tggatcaatt cttccccgat tactttgcgt gcaagagata gatgttgcgg
    24901 atcaacgaat cgaaaaaaat aattcagtga tgcatcgaaa gaaatactat gaaaaagttc
    24961 atattcattg atttctaatt ctaatacatt cgctgtcaga agccggcggt atttttccgg
    25021 tccttcgatc tcgtatccct ggttccgaat gatttccaaa ggcagttggc gaatactttc
    25081 ttccaactgt ttgatatctg cataaaaagt ggtattactg atgcgatatg attccatgaa
    25141 atgagcaaga ctcaacggct ctgtcgtcag taacaactcg gctaaaatcg cgtgttgtcg
    25201 tttagcagtg gataagtcat tacttttccc atctgtattt tcttttaatt gctctaatac
    25261 ttcttctgat gcctcaatga caaatgagcc tctagctgct tttttcaaag aagcatttac
    25321 cgatttcaat gagacttcaa gattatctaa ttcgcggtaa atagtccgtt tactgacctt
    25381 caataaattc atcatttttt ggatagatac aggtgacggg ctactgagaa attctgctaa
    25441 taattgtttt tctctgggcg ataaatacat cttatatttc tcccttcacg agtttttcgt
    25501 attcattcgt agctacccaa tgttcaacta gaactagccg agggatcttt tcttctagct
    25561 gttcagttac agctagttct ctttgtgcga tataaatcgt ttcttcttgg attttgattt
    25621 tttctattga ttcttttgag ataacaaact gttttttcgc tttttttgct aattgactta
    25681 aaatcgtcat gcccatagtt tgtgagccgc gtctgttgtt tttatacaaa aatacaatat
    25741 tagcaggcga cgttttttgt tctgtgatat ctgctatctc ttttttttct tcccgctttg
    25801 gaaattggat cgcttctttt attcgtgaca gcaagatatc tgtttccaaa aagtgatcca
    25861 gtacatagat ttgactttga ggtacttttt ctcttgcaag acccgctagt tcatgttgca
    25921 cgataaccag ctgatttact tggttattca attcatagat agagctgtat ccgacagaaa
    25981 gatcgatttt ttctgctgct aatttctttt tcagcagggc ggctcccata gcacttgatc
    26041 ccatacctga gtcgcaagca aaaatgacgg aatgaatgat agatggttcc aagatttctc
    26101 ccctttcttt gaccgttttg ttctcttttt ctttatttgg taatttcaat agtatcgctg
    26161 cacaaatgaa ggtcacaaat gtactgattg ctatccctat acttacccca gctagttgtg
    26221 gataaggcgc attggcaaaa atcacgagta gtgacccagg cgatacaggt gcagctaatc
    26281 ccgtatctaa ccattgaaat atcaacgtgc cgcttgcccc accagccatt acagctaaaa
    26341 atagatacgg tcgcagcaag acaaatggaa aatagatttc gtgaatcccg ccaatcgcat
    26401 ggatcatcaa tgctccactc gcatttactt tttcctgttt ttctgcaaaa caaaggatag
    26461 aaagtaagat ccctaaacca ggtccaggat ttgcctccat caaaaataag gaagagtacc
    26521 cgactgtttg tgagaattcg attcctaaag gtgtcaatac accatgattg attgcattat
    26581 tgaaaaatag tacttttaga ggttctaaga tcagactgac aagtggtaac agattcattg
    26641 tgactagcca agacacaacg gaggcgagca acaagtgaac actatttaaa actggttcaa
    26701 taaaaacgat tccaattata caaataacgc taccagtcag tcctactagt aggttgctga
    26761 caagcatttc atatccagcc ttgaatttca catggaatct agaaacaaat tgttcatata
    26821 cgatgccggc aagcggcccg ataatcatcg ctcctacgat ttgtggagca ttggaacgag
    26881 cgatcaaccc taaagaagca attgcaccgg cgactgcccc tttttgtccc cctaccgatt
    26941 tcccgcctga ataactgatc aagatgggta aaagcagctg gatcatccaa tggcatacct
    27001 cttctaatgt ggtgtgcaaa tcgccagaca caccttttgt tgctaatgac aagattcccc
    27061 aagcgataaa cagacttaga tttggcatga tcatttcatt taagtgatgt ccagcttttc
    27121 tcagttgttt catagacacg cgactgctgt tgtttgcttt ccatttgtat tccatctttt
    27181 tcaccagact tctatttatt gatggacgga ttttatgtag aaaaagcagc aaacgaaaaa
    27241 ccgtctgctg ctttcagcta tctgggaact atttgcctgg ttcagacgca atgattgcta
    27301 gttcaccttg gaccgcccac tcagaaacgc catttggaat aatacagctt gttccttttt
    27361 ctaatggata tgtttttccg tcaacgacaa ggtctcctgc tccttcgatt accgtcatca
    27421 atgtataagg ggcttgtttt ttgaaagatg tgattccttt aatatcccac tcatatacat
    27481 tgaaaaactc agtttctaaa taagtgacga tcgatgaatt cccttttcgg acttctttga
    27541 tttgtaattc tggtgttttc gcagggacag ttgttacatc gatcgattgt tggatatgca
    27601 gctctcttgt ttgtccttgc gcatcttttc tgtcgtagtc atacacgcgg taagtcgtgt
    27661 cagaactttg ctgtgtttct aaaatcatga ttcctttacc aatagcatgg atcgttccgc
    27721 ttggtacata aaagaaatca ccttttttaa ctggtacttt cttcaaaagg tcatcccagc
    27781 gcccatcttt gatcatctca gctagttctt ctcttgtctt tgcatgatga ccatagatga
    27841 tttctgcacc aggttcagca tcgatgatat accagcattc agtttttcct aattcacctt
    27901 catgtttcat cccataggca tcatctggat gtacttgtac agatagatca tcttctgcgt
    27961 ctaagatctt gatcaataat ggaaacactg gttctgaagg atggccaaac aattccttgt
    28021 gttctgacca tagttcatct aatcttttcc ctttgaattc gccattttct actacactga
    28081 caccatgagg atgcgcactg atcgcccaat cttctccgat tttatcgtta gggatatcaa
    28141 aaccaaagac tgaacgtaaa cgacttcctc cccaaatttt ttcttgaaaa actggtttta
    28201 aaaacatagg ttcctgcata attcaaactc ctctcatttt tcatagctat tatagcatta
    28261 tttcggtaat accgctttct ctttcaaaaa gttttcaaca atttcatctc gacatatgag
    28321 atactccgca cgatgatcga caggatgtac gcgatttgac aaaaatatca acgcttcttg
    28381 tgtttttata tcaatcaaga aaaacgtacc tgtataacca gtatgaaaaa gaatcgcatg
    28441 accgtcttct acatcctttt ttaagtccca tcctaaagaa cgatagccat tttttttcgg
    28501 tgtttgatct tgcagtaaag aatcaatcgt ctcttcttct aaaaaacgac cattacggat
    28561 ttttcccttg ttcaaataca tttggacaaa agtaatgctg tctttcaaat caataaagag
    28621 acccgcgtta cctgcatgtt cagccaaaac tcttgctttc ggatcatgag tttgtccacg
    28681 caaaacctca cccgaaggca gttgttctgt gggaacgatt tttttggaag gaaaaggaag
    28741 aaataagctg ttcatcattc ctaatggttc caatacttgt tcttgaaaga tttccactgc
    28801 agtttcttgg taaatttcct ctagcatcaa cccaagaaga atcgtaccgg catctgtata
    28861 ttttacttct tttcctagtt gctcacctgg ttctagcttc aaataagcgg cgatcaattc
    28921 ttcctgagat agcttatctc tgtttggtat ccatgttttg atatcagaag tatgtgtcag
    28981 taaatgacgc aaagtgattg tctgattttc aaattcagga agatatttat gaagcggttg
    29041 atcgagttct atctttccat cttctaatag acgtaaaact aatgaagtgg ttgcaacgac
    29101 tttcgtcagt gaggctgcat caaacaacag atcttctgtc atcagctgct tttcaggaac
    29161 gacttgggca aagccggctg taaatgtttc tacttgattt tcttttatga aggcgactgc
    29221 tacacctgga taaaatcctt cttccatctt tttcaaaata agctgtttcg tgtgtggata
    29281 catctttttc tcctgctttt ctatcagatt cttacagtcc aagcttaaag cttaatctat
    29341 gaggaatcaa ccttttttac acaaaaaaac tgcgcgaaaa accgcgcagt ttcccccggt
    29401 atactatttt ctctttctat ctctagaata agcgatagta tgaccgttca taaaatgacg
    29461 agacatgcga caatcgttaa gaaagaaaaa gttaagcgtc gcatcgaatg tcagttttat
    29521 tcttttcttt tggctcactg acgaaccacc attcgattcc tatagcatca tagattgtga
    29581 gtactgtgtg ctttttgtct aagaagaaat caactgatag ttgctgcaag tgagcaatca
    29641 gtccttccat gctttcagta tcgatcatga atttcagaaa atcaagtcca atcacttcat
    29701 ctgtaggcaa atcaattgcg cctccgctag cttctgtcaa accaacatgg aaatctcctt
    29761 cattcaatac atggatgccc tcttcttcat tatgtacctt caaaccaagt acatgattaa
    29821 gaaattggcg ttcttttgtt aagttagtaa catttaaatg gattttttca aaataagaac
    29881 ctgttgatag tttactgaat ttttcttcag attttcttaa taatgcttct tgatccattg
    29941 tttctggaat ttctctttgg tcgttcttat tctcttcatg gtaaatttcc aattcattct
    30001 cttctgggtc tacgagcaaa atccccatac gtccatgatc ttctaaagct tctttgattg
    30061 gataattcat tttacggata cgacaaagga tatctgccat ttcttctgtg ctagggataa
    30121 tcaatgaaaa acggttcagc tttttgatca cccccatgtg atcattcgct ctaggacttt
    30181 cttccagcag caacatttca cttccagctt cttctgttcc taaaatggct aattcgtttt
    30241 cttctctttt caaatcaaag ccaacaacgt tcttgtaaaa atcaatcatt ttatctcggt
    30301 ctttcacccg aatggctaca ctttttaaat aggtggcagc ccccaattga aaatctttca
    30361 tatttcttgc tcccctctac gtcaagcttt attttaacga tggattcttc ttctttcaag
    30421 caataacttt gattttgtta aaaaaaatgt gagaaaattc gcattttgct tgttttttgt
    30481 aaattaatga gtaaaaactc ttataaaaag aggttgtgaa aaagctgttc tgcatcaagt
    30541 aataagaaca gccaaacaaa aatagctcct cctatttttc gtttggttgg gcttattacc
    30601 gcagatgcaa gcttttgaac accgtttaag gaagaggttg tgaaaaagtc gcttagtttc
    30661 gagtagtaag aaaaattttg tgaaaatggc tttctacatt tttgcataaa tttggcttaa
    30721 taccgagaaa ctggcttttg aacaccgttt accaagaggt tgtgagcctg ccgtttaact
    30781 ccgagtcaca aggagcaatt tcaaaaaaca gcttctcagg tttgttgact attgtgactt
    30841 gtgaccgagg agttggcagg agaacaccgt ttaaggaaga ggttgtaaaa tcagcggttt
    30901 gacctgagta ttagagatac aaaacggaaa aatagcttct catattttgc cgttttttga
    30961 gctaataccg aaggacagct gattgaacac cgtttattcg gaaaaaggga ctgtgacacg
    31021 acttttgtca cagcccctaa aaaaaataat aaatttgtac tattctatga agcttcttct
    31081 tcagaaaact gactgttata aagatctgca tagaatccgt ctttttccat caatgtatcg
    31141 tggtttcctg tttctacgat cgaaccatga ttcatcacaa taatgttgtc tgcatcgcgt
    31201 attgtagaca agcggtgagc aacaacgaaa cttgtccggt tttccaatag gcggttcatc
    31261 gctttttgaa tcagtatttc tgttcgtgta tctacactag atgttgcttc atcaaggatc
    31321 aggacatctg gatttgctaa gaatgcccgc gcaattgtga ttagctgacg ctgcccttgc
    31381 gaaatattgc ttgcatcctc gtttaataca gtgttatatc cttctggcaa tttacgaaca
    31441 aaatcgtcta cgtgagcagc tttagcagcc tcaatgattt gttcgtctgt tgcatcgtcg
    31501 ttcccatatt tgatattgtc atagatactt cctgtaaaca gccaagtatc ttgcagtacc
    31561 attgaaaact gtgcgcgcaa ttcatcacgt gaaagatcac gggtatctac accatcgtaa
    31621 cgaatactac ctccagaaac atcgtagaac cgttcaagaa ggttgatcag tgtcgtcttc
    31681 cctgcaccag tcggacctac aatagcgacc atctcaccag gtttgacatc caagttaaaa
    31741 tcagtcatta gcaagttatc tggtgtgtag ccgaattgaa cattttcaaa acgaactttg
    31801 tatggtgtat ctttttcttc tggaaggcca gatttttcat tggacatctc ttcttcatcc
    31861 aacacttcaa atacccgttc ggctgaagca actgttgatt ggatagtgtt catcaaactt
    31921 gcaagttgag tgattggttg agagaactgt gttgtatatt gcaagaacgc ttgaacatcc
    31981 cctaatgtca tgttcccatt tgcaactttt actccgccta gtacagcgac gaacacatag
    32041 cctagatttt taacgaaatt catcaacggc atgatgattg ccgaaataaa ttgagctttc
    32101 caaccagcgg catacagatt ctgattttct ttttcaaata cttcctggtc tttttcagta
    32161 tgattgaatg ttttaacaat ggtatgacca ccatatgttt cttctacttg gttattcaat
    32221 aaacctaaac ttttttgctg atctgcgaaa aacacttgtg atttcggcgc tacgatcatc
    32281 acgatgatca agcttaaagg gatcatcaat aacgcgacta acgtcaattg ccagctgatt
    32341 gaaagcatca tcacgatgac cccaatcaat gtgactgcac tagttacaaa ttgagtcaaa
    32401 ttttgctgca gcgtgcttgc gatgttatcc atatcattga ttgctcgaga catgatatcc
    32461 ccatttgtat gtgtatcata ataggaaatc ggtacacgat tcattttggc ttccaaatca
    32521 tgacgtaatt cataaactgt tcgttgggaa acacgtgtca taataaattg ctgtaaaaag
    32581 ttgaatacag cagaaatcaa atacatcacg attactgtcg caatgatctg cgcgatttta
    32641 tcaaagtcta tcggaaattt tgttacttgt tggccttgtt gcatctgttg agcgccagcc
    32701 attacacctt tgaatatttc tgtggttgct ttccccaaga cctttggtgt ttggatttgg
    32761 aagatcacgg ctgctattgc tagtacaaat acagcgatga tcgcaaccat acgtttagac
    32821 atatagccaa acaatcggcg taccgttccc cagaaatttt taggcttttc accttttaca
    32881 ccgagatttc tgccaggtcc accatgtcct ggaccgcctg ctggtccatg agagggacgt
    32941 gtgtttgttt tactcatgct aagtcctcct ctcttagttg tgaatgaacg atttcttgat
    33001 aagtttcgtt tgttgctaat agttcttcat gtgttccttt gccaaccagt tttccttcat
    33061 ctagcacaag gatcatatct gcatccatta ctgtacttac tcgttgagca actaaaacgg
    33121 tgatactttc tttcatattc gttttcaatg cttggcgaag attggcatcc gttttgaaat
    33181 ccaacgctga gaaggaatca tcaaacacat agatatctgc tgttttgact aatgcccgtg
    33241 caattgccag acgctgtctt tgtccaccag agaagtttcc tcctccttgt tccacatggc
    33301 tatctaagcc atcttccatc tctgaaacaa aatctttagc ttgtgcgatt tctaatgctt
    33361 tccaaatcat ttcatctgtt gcatccggct taccatactg catattgtct cggatcgttc
    33421 cagagaacag aactgctttt tgaggaacaa agcccattaa ttctcgcaaa ttatattgag
    33481 tcatgtcact aatgtccgtt ccatttattt ggatcgaacc agattcgatg tcatataatc
    33541 gagggatcaa attgactaag gtcgttttac ctgaaccagt cccccctatg attgcgacga
    33601 tctcgcccga cttggcttgg aaatcaatat cttccaatgc aagtttttct gctccatgat
    33661 atcgataatt gacatgattg aaggccaatg ttgcgttttt tccagcaaaa gaaactgttt
    33721 taggattttc agggtcatgg ataccgattt tttcatccaa cacttcatta atacggtcag
    33781 ctgaagcttg tgcacgaggc accatgataa aaatagcgga aagcatcata aagctgatca
    33841 agatctgcat cgcataagtc ataaatgcaa tcagattacc gacttccaaa gtcatatctg
    33901 ctatgtagtg tccaccaaac caagtgattg ctacgtttgt accgctcatg atcaatgtca
    33961 tcattggcat catcaatgcg acgatcgtat taactttgat tgccgtattt gtataatctt
    34021 tattcgctaa atcaaaacga ttttcttcaa agcgtgtctt atcgaatgct cgaatcactc
    34081 tgacccctgt caatccttct cgaaatacca ggtttaaacg gtcagttttc ttttgcatac
    34141 ttttgaataa tggaacagca aagtacatga ttccgccgat caaaataatc attactggga
    34201 tgacaactaa gaagattttt gtcaactgat gatctttttg ataagcaagt atgctcgcgc
    34261 caatcaacgt gattggtgca ttgatcatca tacgtaaaaa catttgtgta accatttgga
    34321 tttgagtcac atcattggtc gttcttgtga tcaaagaggc cgttccatat ttatcaaacg
    34381 catcttttgt cagactctct gattttttat agacatccgt acgcaattgc ttacccagtt
    34441 tctgtgattc acgagtagca aaaaatgtat ttgcgatagc agctaagata ctgatcaaag
    34501 aaaagccgat catcacaaaa cctgtatgcc aaatataatc gacatctcct tgcgctaccc
    34561 ctttatcaat aatattggag gtaagtgtcg gcaaatataa atctgccagt acttggatca
    34621 ccatgaaaac tgcagctgca attgctgaag tcaaggagat ccgttttacg atttttagca
    34681 tctagttccc ttctttctat ttatatactc cgtttttcag ccaagaaagt ttcaaattga
    34741 attcactgat tgcttgctct actgagtaat cttcagatgt tgaaaataag cgatacgaat
    34801 gcgcaattgt tgtaaataca gtattcatca ctaattggat cagtaattcc aattcatgat
    34861 cattttttac tttcagcttc gtccgatcga tcaattcaag caactctttt gcatcttgtt
    34921 tgtgttcttt atgtggatcg tgaggcgttt tttggcgact cgtatgagga gcgacttttc
    34981 ttgaggcacg gtaatccatg ttcataaaca agttacgata aaaagaagca ttctcgcctt
    35041 ccaaaatctc ataaatcatt ttagaaaaat aggattcgaa tcctttgaat agatcaccat
    35101 cggattcttt cattagttgt aacatatctt tagagctgtc acgtctcatt gtctcaaagt
    35161 aataaaaata aagatcctct ttatcttcaa aatactgata gaaactgcct ctagggatat
    35221 ccgctaattt gacgatatta gcaatcgaag cttcttttaa gggtactcta gaaaactcga
    35281 ttctcgcagc ctcgattagt cttttttgtt tttctttagg caaatggaaa aatgtctgtg
    35341 tcggcatatg gattctcctt tctttcaaga tgacacattg tcatatgacg ctatgtcatt
    35401 ataacacctc ctacctgttt tgcaagacat ttgcatagtt tttttcatta tcatccgata
    35461 cattaaaaaa gtgataagag gaatccttcc atttgaatta atgagagttg cccattaaaa
    35521 tagccacata ctaaacaaag gatgagataa atggcccaat caattagtgt ccaagacttc
    35581 aataaattgc ctctcgatgc tgacagcatc gttttagata caagaaatac cttagattac
    35641 acaaaaaacc acttaagcca ctcgctttct atccccgctg ctatcttgcc aagacaatta
    35701 aaaaatctag atccaaagaa actttattat attctaagct atacaggcag gcgatcagaa
    35761 gcattagccg atcaacttac tgctaatggt tttcgtgctg tttatatcat tggtgggatg
    35821 gaagctcttc agtcgagtgt tgcttgaata ttgcttgtta gattcaaaag aggctgtgac
    35881 aaaaaatcgt gtcacagcct cttttatacc ctgtcttttt ttagttattt attcttcaac
    35941 cttatcaata tgacttgata gccttttctt tttcgagtaa actgattttg ttagtcatag
    36001 ttataacaat catagcaata aaaggagaag gtaagcatat ggcatctgtt ttagtagtca
    36061 aaggtcatcc cctaactgca gaagaatcgc gcacagttaa ggcattgacg tcttttttaa
    36121 caagttataa agaaaatcat ccagatgatg aagtgactgt tttggaactt tatcgcgatg
    36181 atattccgga aatcgatgaa gaattattat caggttggga agcattacgt gctggtgcag
    36241 aattcacttc cttatcagaa agtcaacaac aaaaaattgc tcgtttcaat gaattgactg
    36301 atcagttcct tgctgctgat aaaatcgtta tcgcaaacgc cttatggaat ctaaatatcc
    36361 caacaaaatt aaaagcttgg ttcgataccg tcaatgtagc tggaaaaacg ttccgctata
    36421 cagaaaacgg gccagaagga ttagtgacag gtaaaaaagc actgcacatc caatctaatg
    36481 gcggtgtata caacggacaa gactttgcct ctcaatatgt aaaaggtatt ttaaactttg
    36541 taggcatcga tcaagtagat cagctattca tcgaaggaat cgattatgac cctgaccgtg
    36601 cagatgagtt gatgcaaaat gcattagata aagctgctgc tttaggtaaa tcattttaaa
    36661 aattgagata aatgcataca aaagagacag aggaaaaaat cttcaaagca gcatttgtgc
    36721 cttggatatt ttcccatctg tctctttttg ttattctttc tgctttttca acggattttc
    36781 ttcataaaga gaagagattg ttgtgtacca ttcaaaaaca tgagtaatca ctactttagc
    36841 tgctgcataa acaggaatcc ccaagatcac accgatgatt ccgaacaatt tcccagaagt
    36901 cagcagaact aataaaatcg ttactggatg gattgctaac tgattcccta gtactaatgg
    36961 agagatcaag cgtccttcta ttgtctgctc tactgcaaaa acgatcagta ctttgatgat
    37021 catgaatgga cctgctacaa tggctaaaaa gatagccgga atcatcgcta aaaatgatcc
    37081 taagtaaggg atcaggttta aaaaacccgc aataatcccc aacgtgacag catactctaa
    37141 accaatgacc gcaaaaccaa tcataaacat gattgccaca gcaaaagcca cagttagttg
    37201 tcctcttata taagaagaaa cttgactatt catttcactc agcacattca acgtcggttt
    37261 ttgcatgcgt gtcggtaaaa atttgacaaa ataaggtgct aattgtttac cgtctttcaa
    37321 tagataaaat aagataaacg gcatcgtcag cagagccact aaaatagtcg ctaccgcgcc
    37381 gacaaaactt ccaagactct gaactgtact cttagatata tcttggatca tatcgcctgc
    37441 cgaattcatg aacttatcac ctgctgtttc caactgttcg cgaaattggt tgaacagcgg
    37501 gtcccgcaaa atctcggtta atttattatc aatcgtatct acatattgag ggaagttact
    37561 gatgaagctc actgtttgtt cctgaatctt agggatgatc actacgctcc cccatgcgat
    37621 tagtgcaaca accaaaacaa acagcccaat gatactgtaa agccttggta cttttcgctt
    37681 ttcaaagtaa tcaactaccg gattcatcaa gtaatacaag attcctgcta aaatgatagg
    37741 cagacctacg attgctaaaa attgccagat tggtgcaaac aaatatgaaa cttttgtaaa
    37801 taaaaagacg atcagcaata ttaacaatac aacaagtaag gctgtgacta cttgattatt
    37861 taaaaaccag cgccaaaacc acgataccgg tctgttcttc ttattttttc cttccataat
    37921 tcctcctgtt agttataaaa aatttggctt cccaaaccaa tagcaggcag tctatgcgga
    37981 tgaagataga ttccatttgc aatttgtcct tcttctggac aagcatcaaa aatcaatgat
    38041 acgtgagcta ctgtctttaa attcccattg gccatcggac cgacataatc gatcgtatat
    38101 acctgatcat caaaagcaat tgttccgcct gctttcaaag aaaaaggttc gtcttttgat
    38161 acttcttgaa tcaccgaata ttttcgtaag gcagctgttg ctgttttatc gaacaaaatc
    38221 agcatgggtt cttccttgtt tattgcttct gtcccaattt ctgtaatctt tgcctgaatc
    38281 attgcactct ctcctttaat tgctttcaaa aacagtataa cacattctca ttctttagcc
    38341 gtgtggaata attatgtgat agaataaaaa cgaaaactat ttcattacaa ttaggaggaa
    38401 tcagctcata tgatcgaaaa gataatttta ggaacctata cgcgtcgcga aagtaaagga
    38461 atctatacga tcgaccttga tacagaaaaa gaagaattag ccaacctttc attagctgtt
    38521 gaagaaaata gccctaccta tgtagcaaaa agtaaagctg gcaatcttta cacagttact
    38581 agtgtggatg gattaggtgg tgccggtgcg tacgataagg attttcattt tttgaatgcg
    38641 gtaacagagt ctggcgctcc tttgtgttat gtagcggttg atgaagcacg tcaattacta
    38701 tacggggcga actatcataa aggtgaagta aatgtctacc atatattagg agatggcgaa
    38761 ctgaaagcag cagattcaat attccatcaa gaagcgacag gtcctcataa aaaccaagat
    38821 catgcgcatg tccactatac ggatctgact cctgaccaac gattagtcgt atgtgatctt
    38881 ggtacagatc gtgtgtatac ttatgatgtg tccgaaaacg gcaaattgaa tcttgtaact
    38941 accttcactg cagagccagg aacaggccct cgccatcttg tctttcatcc aaatggacaa
    39001 ttcgcttatt tatttggtga attagacagc acagtccgcg tgctttctta taataaagaa
    39061 acaggtgctt ttgaagaatt acagaaaata tcgaccttgc cagaagaatt cgacggtgaa
    39121 aatggagggg cagctatccg catttcaaat gatggcaagt tcctttatgc ttctaaccga
    39181 ggacataact cgattgctgt attcgcagtt tttgaagatg gttcccacat tcaaaacaag
    39241 caaatcatct caacagaagg ggattttccc cgcgatttcg cactagatcc aagcaataat
    39301 tttgtcgtgt gtgccaatca gaacaccgat aatctgacat tatatcgccg tcatcctgaa
    39361 acaggattac tggaattact gaaaaaagat gtctatgtac cagaatgtgt ctgtgtttat
    39421 tttgatcgtt agtaagaaaa ggagaatgaa atgaatcagc aagacgtatt agacagacta
    39481 cgggaagaac taaatattcc tttctttgat gggaaaatcg aagataaaga gtatagcgaa
    39541 gaggaatatc agaaactcaa agccgattta cagaactact ttgaacaata tgtacagaat
    39601 gtagaaaact aatcagcttt ccatactatc tgaaaagaac atcaggacaa gacttttccg
    39661 tctatcctga tgttcttttc tacaaataaa aaaccgccga gatggttaga ctcgacggaa
    39721 aaggagtatt tactcgattt tgagtaagta caaggttgtt gttggttata ggtatgtcat
    39781 tatcataaag gattttgatc actctatcat aaaggtaata ttacatttat attagataac
    39841 tctagttttt attgttatca aagatttctt ttattttttc aacaacaaat tagtcatttt
    39901 ttggatggca gctgtcaatt ggtctgtcgc ttggtcttgt tttgcttcag atgtattgaa
    39961 tagatcttca tctacccctg attcaagatc gatactttgg atcatttctt cacagcctgc
    40021 tacatatgaa agataagctt tttcaaaatt tttatgaatg cccattgctt ttgctggtgg
    40081 acgcaaagta ctgactttca taagcattgc ccgatatttt tttgttcctt cttcaaataa
    40141 caggatgatc tcttcaagag tcgatttgtc cagttcactt gtttttcctt catcaattgc
    40201 gtttctgatc acttcatatt tcggatgcat tccttctccg attgcttctg tttccttgac
    40261 gatttgatcg atggactgca cataatagcc aatattcggt aacatgttcg ttttcctact
    40321 ttctccattg ttgttattat ttattctact tgtttttatc ctcaaatgac aagtacttga
    40381 aaaaatttaa tggtttctat acagctcgcc attcttattc gtgctcaaag aaaccatctg
    40441 ctaaactata ttgtttccct gcgacaatgt catattggat caattgatat tcgtcgtaaa
    40501 tctcttgttg cgagcgattg aattgcgctt ctttatacca ctgtccgttt tgatagtaca
    40561 gttctcgttc aaacgccgga agttcctgtt ctaatgataa aagcagctga taaaagccat
    40621 ttgttgtctg attcgtctgt tccattagat tcgctgcaaa ataaaacgga ctggtgattg
    40681 catcgtgagt cgtttgcttt tctaattctc ctttactgtc gaacataaga aattgtgttt
    40741 catgcaatgt ttgtttgtca ttttttgctt ggatcgtatc tgaatagatc cctggaagat
    40801 gatcccccca aaaaacaact aaagtccttc tagaaagatt cttcaattct tccgtgaact
    40861 gcttcagtgc cgtgctgcta taggaaatat cttgcagata attctctaag tcaagtgtcc
    40921 cacttccatc tgaagttttt gcaggatagt ctagattatc atactttcca tcgtagggca
    40981 tatgtgtctg catcgtgact aaatgaatga actgaggtgt tttttcttcc ttgagaagtg
    41041 tcattacttc tttgtaagct gactcatcag aaatatatgg attattctct atcgtatccg
    41101 tataggtcat cgtacgctcg ctgatgaact ggtcaaatcc taatgtctga taaacatcct
    41161 ctcttttata catcgaagta ttgtatggat ggatcgctgt cgtctggtat gattgtgcgt
    41221 ttaacgctga aacgatagaa ggaagctgat ccatttttgg tacaagcatc gtgtaagggg
    41281 tggtgagttg cgcattaaat aacgccatag aaaaaccagt caatgcttca aattcgatat
    41341 ttgctgttcc accgccatag ttttgagaaa gcatattgcc actatatgtt tgatcagcta
    41401 cttcataata atctgccaat ggctcaccag atacttctac gccgtttaat cgactaggat
    41461 ctgagaaact ttcactcatc acgaacacga tgttcggcga ctcttcctct acagttttat
    41521 ttttttcatc ggctagcttc tggtattttt cagtgatttc tttgatcttt tctttcgaat
    41581 atccttcagg ttcatccatt ggttctacct tcagattgta caaaaaccca ccgataaaac
    41641 cagtgttata gtagttcatt ttctggctgt aaggtatcca tagtgccgtt ttattatatg
    41701 cttttcgcaa caaattatcg ggattgttga aattactgat ataccctagc agtccaattg
    41761 ccacaagcag tgtcgttaat cggatcaatt ggaatcgcct tccttttttc aggcttcgaa
    41821 acatgtacca gcaaaacaat cctatcacgg ttcctgcggc agctaagatc actgtaaaca
    41881 gcatagtgcc ggtcatatct ttcagcaatc cgatttcagt gatcatcttc aaatcgtctg
    41941 gataaatcgg ttcttgccga taactcattt tcatataatt tgcaaaacct aatacaccga
    42001 tggctacgac atacgtaagg gaacctaaag ggacagatcc tgctagtgca atcagaaaaa
    42061 taagaataat cagcaagacg agacaggcta agaagaattt ttccgtatgc caagaaaaag
    42121 caaatttcaa cgcaaggtct acggatagat cattttgaca ccactgcaaa aataaattac
    42181 taaaaacaac aagaaaaaag atactgatga ttgctgctgt tccttttaaa atctttttct
    42241 gtttggtcga aagtctgctt atatatcttt tcaaatgctt gctccttcat ttctatcaat
    42301 aaaagaatgt tgcttctctt attttagttg tacgaaattc gaaagtaaag aacggaaaga
    42361 agaattaatg aaatccaaat attctctttc tttatggcct ttctggtttc tttaataagc
    42421 ggacctttcg tactccagaa attttttcta gctgttgttt cacttgattg agctgttcaa
    42481 aatcagtact gtctatgtca atcaatatgt agacatgctc attcttatgg ttacgcgata
    42541 tatctgcgat cgctagctcg ttctcattca gcagagaaaa tatctctgct aatatattgg
    42601 ttttcttttg ataaaatata gtgaatcgaa acggcgcttg gaaaaacatt cgtgcggatg
    42661 gataattgac cgcttctcta accgtaccga acaaaagata atcttttaag gcttcaactg
    42721 ccaaacgtcc gctgtctgcc aaagcttcct gagtcgatcc cctagatgag gcaacataag
    42781 tatacggtca ttttctaaga actcttcttc tggaaaatca gtcaagtatt tagccagatg
    42841 ttgtttttcc aatgcttgca taacagcata tttatcaaca atttcacttc ttcctacatt
    42901 gataagtaca gcatcttttt tcattttttc tatattcgcc tgatcgatca atccttttgt
    42961 atcttctgtc aacggcagca tgactacgat gtaatccgag gtagaaagaa ctgtttctaa
    43021 atctgcttgc cgaacataat ccaactgggc atcgcggata gaataaccca agacatccat
    43081 ccctaagcta tagcaactta gcgctacttt tgtgcctatc gctccaagac caagaagacc
    43141 gatggttttg ccttgcaatt ctcgtcccac ataagcactt cttttgtttt ctgcctgttc
    43201 taaaatatta ggacctgtta gtgtttgtac catacgactt gcttcgatta tcggacggga
    43261 agataagagc aaacagcaca aaacaagctc ttttactgca ttagcattta cacctggtgt
    43321 attcatgacg atcgtcccgt tttcagaagc tttttcaacg ttgatcgtgt tcaccccaac
    43381 accagctctt gaaattgcta gcaaatctgg tgtaagccat tcatctttca ctttcgtact
    43441 acgaataact attccttcgg ctggcaaatc atctattatt ttgaaatatt ccccttgtaa
    43501 cttttctatc tcttgttctg gaatagcatc aatcaaatga acgtgataca taaaaccccc
    43561 tccttactaa caagtatctc gaaatttctg caattagaca actgtttacc atttgacttc
    43621 ctagaagcaa aaagagcagt tagagcagag taggctgagt gataaaaata aggctatgac
    43681 aagttactgc cataagcctt attttcgaga gcaaaatatt gagggtgaga tatcttgata
    43741 aatggtgttc cgttagctga cattgataat aagactaaat ttcaaaaaag ttgaaaagca
    43801 aatttcgtca atctcttctt atttcttaaa actaagtggc tttttcacaa cctcttttta
    43861 tctaataacc actgtttcca actcaactaa ttttgcccac gtttcaattt gatctgttgt
    43921 tagatttagc gagacaacgg tatgatgacc gccacctgcc tgaatccatg aatggacacc
    43981 ttcatggaaa ttcggtttag ttttccataa cacacgtgca acaggtaaat taggtgcttc
    44041 agtcgttggt tcaaaggctt ctacttcatt gatcagcagt ttataatgcg taccgaaatc
    44101 tgccatcgat acgactaccc cttctcctgc tttcccatca aatacaagac gcgccggatc
    44161 ttctctatct cccattgata aaggagaaac aacgattctt ggtttcgtcg cagcaagcgt
    44221 cggatctact tccatcatat gggattccaa gattgcttct tggccactag ctagctcgta
    44281 agtataatct tccatgaatc ctgtatcttt ccctcgagcc atgattttca gcaaccgatc
    44341 aatcgctgca gttttccagt cgccttcccc agcaaaaccg tatccttctg ccatcaaacg
    44401 ttgtacagct agtccaggta gttgtttcat tccatacagg tcttcaaaat tagtcgtaaa
    44461 agcgttatag cctccttctt ctaagaaacg gcgaataccg atttcctgct gagcttgtac
    44521 ttttacatgt tcctcccatg tcttttcttc ataatcacca tagtcgaagg tatacaattc
    44581 cttgtactct tcaaataatt gatcgacttc ttcgtctgat acgcgatcga ttacttgtac
    44641 aagatctccg ataccaaaat aatcaacagt ccaaccaaat tgaatctgtg cttccacttt
    44701 gtctccttct gtgacaccca cgtttctcat gttgtcacca aaacgagcca cttttattcc
    44761 aaaactttca ttataggcta ctgcaacatc catccaatca gcaatctctt tttggatctc
    44821 aggtcgtttc cagtagccaa cgacgatttt attttgttta tttaatcgag cattgatgaa
    44881 cccatattcg cggtcaccat gagcggattg atttaaattc atgaaatcca tatcgatcgt
    44941 tttccaagga atgctttcgt tatattgcgt agctaaatga agcaatggtt tttgtagaag
    45001 ctttgtcccg cggatccaca tttttgctgg tgagaaagta tgcatccaag tgatcacacc
    45061 tgctacttct tctcgataat tgacctcttt catgattttt gtgatcgtat cagcagtaac
    45121 tgctaattct tgaaggcgga ttggataagg caattggcca ttttcattca gttcatcgac
    45181 catttcttgt gcatgtttct ttacttctcg cagtgcttct tccccatata aatgctgtga
    45241 tcctacaaca aaccaaaatt ctttttctcc aatattcaac ataattagcc actcctttta
    45301 tttgttttgt ccgtaatacg cattttttcc gtgttttcgt aaataatgtt tatctaaaat
    45361 ccgttgaggc agctcttctg aaaatgaatt gagctgtctg gtaaataaat tcatcttgca
    45421 tacttcatct agtacgactg cgttcattac cgcactttgc gcatctttcc cccaagtaaa
    45481 tggaccgtgt ccgtgtaaaa gtacccctgg aattgctaag ggatcaattt tgcgttcttt
    45541 gaatgtttct atgataactt ttcctgtttc atattcgtac ccgctgtcga tttcctgttg
    45601 tgtcaaaaat cgagcacaag gtaccgatcc ataaaaagta tctgcatgcg tcgtccccat
    45661 cgcaggaaca tccaatcctg cttgtgccca gatcgtcgcc catgtcgagt gagtatggac
    45721 gattcctccg atttgaggaa atgaacgata taaaacagca tgagtaggcg tatccgaaga
    45781 gggattgagt ttaccttcaa tgatatgatt gtccaagtcc acaacgacca tgtcgtctgc
    45841 tgtcatctct tcataactga ctccgctagg tttgataacg aaatatcgtg tttcaggatc
    45901 aaaagcgctc acatttcccc atgtatattt gacgagtccg tgtttaggca agtcaagatt
    45961 tgcttggtat acttcttctt tcagttgttc cagcattttc tatcactcct ttttcttgca
    46021 attgatgaat cgctgttttt tcaatgtcga tcccctcacg gtaacgtctc ataaatatct
    46081 gatagcctgc tatttcttct gctgaaggtg tgatggtgat tccttggtct tgtccaaaca
    46141 cgtcttctgc caagaagttt tctaaagact tcccatgtcg atccatcata taggctgcta
    46201 ataacgcgat tccccacgct ccaccttctc cggctgtgtc catcactgta actggtgcct
    46261 ccatagcaga tgctagaatc cgctgtccaa cttctggtgt tttaaaaatc cccccatgcc
    46321 ccactaaacg atcaatttgg acattctcag atttcaatat atccattccg attctcattg
    46381 caccaaaagc actggctaaa tggatccgca tgaaattcgc taaatcaaaa cggctacctg
    46441 gtgtacgtac aaataatggc cttccttcat ttactcctgt aatgttttca ccggaaaaat
    46501 aaccataaga aagtaatccc ccgcaatccg tatcgccttc tagcgctttg ttgaataata
    46561 ccgtgaataa tttatctctg cttatctcca tacccaaaga attggtaaat tcttcaaaaa
    46621 tactgaccca agcattgata tccgaagagc agttattcgt atgaaccatg cctactagtt
    46681 ctcctgaagg tgtagtgacc atgtcgattt ccggatggac attttctagt tctttttcta
    46741 atacgatcat agcgaaggcg gaagtaccag ccgaaatgtt ccctgtccct ttggctacac
    46801 tgttcgtagc gaccataccg gttcctgcat ccccttctgg cggacaaacc gggattcctg
    46861 gtctcaaatt tcccgtaggg tcgatcagat aagcccctga ttcgcttaac ttgccagctt
    46921 cttctcctgc tactagaact ttaggcaaaa tgtgatccaa gtcaatcgct acgtgcgctt
    46981 tttcgattaa ctgaccaaaa atatttttca tttcttgatg gtaggttttc gttgaaggat
    47041 cgataggaaa catgcctgat gcatctccta cgcctagtac tttctcacca gtaagctgcc
    47101 aatggacata acctgcaagc gttgtcaaaa aattaatttc tttcacatgt tcttctttat
    47161 tcaaaataga ttgatacaaa tgagcgatac tccatctctg cggaatattg tattgaaatt
    47221 tttccgttaa tattcgttct gcttcttcag tgattgtatt tcgccaagta cgaaatggta
    47281 ctagtaactg ttccttgcta tcaaatgcta gataaccgtg catcattgca ctgaacccaa
    47341 tcgacccgat tgtcgtaaga ttctcgccat agatttcgaa tacttctgct gccatttttc
    47401 ggtaactgac gcgcagtcct ttccaaatat cttctaatga ataggtccag ataccatttt
    47461 ctagtttgtt ttcccactca taactaccag cggcaatagg agtaaaagat gaatcaatca
    47521 atacagcttt gatcctagtt gatccaaact caatccctaa agatgtacga ccatctatga
    47581 catctaacat actttgcgca tttacttcct tcataatgat ttaactccct ccttctcgtc
    47641 aaacctgatc aaaccgtctt tttagtagcg cttacaatga ttattgtata cttttgtacg
    47701 tacatgtcaa gcagttattt acaagaatac aataaaaaac acttgttttg tacgtacata
    47761 agttataaaa tgaaattgct tacaaaatct gatcaaccgc cttctcgaaa ttctagaagg
    47821 agagaatact tatgaaaaaa gaaaaaaaag tttcctcatc gtttatttat ttttttggcg
    47881 catttggcgg cattctattt ggatatgata ttggtgttat gaccggcgcc ttaccttttt
    47941 tacagcatga ttggggtttg gcaggtaaag cttctttgat aggatggatc acgtcttcgg
    48001 tcatgttagg tgcgatcctt ggcggctctt tatctggtct tctttctgat aagcttggac
    48061 gacgaaaaat gattcttctt tctgcactta tttttatggc tggttctgtc ctttctgcat
    48121 ctgcccctca caatggttct tattttctga ttgcagcaag gattcttcta ggtttagctg
    48181 ttggcgctgc atctgcccta gttcctgctt atatgtctga aatggctcct gctagactaa
    48241 ggggaagatt gtcagggatc aatcaagtga tgattgcttc tggcatgctc ctttcctatg
    48301 ttgcagatta tttgctaaaa gggttgcctg aaacgatggc ttggcgcgtg atgttagggc
    48361 tcgctgctgt ccccgcgctg attttatttt tcggtgtttt agctctacca gagtcaccgc
    48421 gttttcttat gcaatctggc cgcttggaag aggcaaaaag agtattgaac tatattcgga
    48481 caccaaaaga agctgaacag gaattcgaac aaatccagct gaatgtcaaa caagaaaaga
    48541 caaccggaac ttcttggcat actttgtttt tagaaaaata tcgttcctta gtcattgccg
    48601 gtattggtgt agcagtattc cagcaatttc aaggagctaa tgctattttt tactatattc
    48661 cgctgatcgt agaaaaagcg actgggcatg cagcgagcga tgcattgatg tggccgatca
    48721 tccaaggaat cattttagtt gctggttctt tgctcttttt ggttattgca gacaagttca
    48781 atcggcgaac tttattgaaa ataggcggta gcgtgatggg actttctttc atcctaccag
    48841 ctgttttagg aactgtactg gatgctcata caaattcgtt gttgattctc ttgtttttat
    48901 gtatttatgt cgcattttat tcttgcacat gggctccact gacatgggta atcgtaggcg
    48961 aaatattccc actagctgtc cgcgggcgag catctggcct agcctcttct tttaattgga
    49021 ttggttcttt cctagttggc ttgctttttc ctgtgatgac tgcttctatg tctcaagaaa
    49081 tcgttttcgg catttttggg atcatctgct ttttaggggt tttatttatt caagagatcg
    49141 taccagaaac tcgtgggaaa tctttagagg aaatcgaaca aagtgcatct aaaaaaactt
    49201 atcctaaacg tatttctatc catcattctt aaagaggttg tgacagaagt ggtcagcttc
    49261 aagaaataag aaggaaccgc ttagtttcca gtcacaagga acaatttcaa aaaacagctt
    49321 ctcatgtttg atgaatattg tgacttgtga ccagttggta ggagaacacc gtttagtgga
    49381 gaggtggtga aagaaacgtt cagccttgag cgatgacaaa agctctcaca aacattgcga
    49441 cgagtaaccg taggagcaat aagaggcggt aaaaacccgt ctcttatttt tcgttttctt
    49501 tcactgtttc ccgttcaact agtacaggtt catagagaat atttggctgt gcctgtcctt
    49561 tttcaatcgt tgtgacgatc caccgtgcgg catcttgtcc caacttttct tttggatgcg
    49621 tcaatgttgt caatttttta ttccctaaat ggcttaaaga agaatcgtct gttcctacga
    49681 tcgataggtc atctggaata tgatagccat tttctgtcaa cttatctagc attaaactag
    49741 ctatttgatc gttatagcaa atgatgccat ctaaagcttg ttcttctttc aaccgttgta
    49801 ctgttttttc agcgattgtt tctcgtgttt ccgtggtgaa agtaatgata tcttccgtca
    49861 aaaaacgcac attatactgt tcacacgcgc tgataaaacc tttcatcctg tattttcctt
    49921 gaagatcgtc gatttttgtg atgaacaaca gacgctgatg tccttttttt atcaaatatt
    49981 ctgctgccat aaaaccgact ttcacatcat ctaaacaaat ataagaggca tttaactctt
    50041 cataagcagc attgatcatc accatcggaa tgccttgttc tctcaaagca acataaagtg
    50101 ctaagtttgg gttatactga ttacttttcg taggctcaac gatcaaacca tctaccccat
    50161 aagcaatcat tttcttcaaa cactctttct ccaattcgtg atcgttattc gtactggcta
    50221 aaagcaatga atacccagat tctcgtaatt cattttcgat tcctcggata atcgacggaa
    50281 aaatataatc agagagatat gtggtgatga caccgatcgt ttttgttctg ttcaatggtg
    50341 ttttttcttt cttatagctg tcatctacat atgtgcccga ccctttttct ttacgcagat
    50401 agccctcatt taccaacaca gcgattgctt gccgaatcgt atgtctgctg acgtcatata
    50461 tttcttgcag cttgaattct gagggaatgg ttgtatttac ttcgtattcc tcacgaagga
    50521 tcttttgttt tatctcttct gcaatatctt gatattttgc catttgcctt gccccttttt
    50581 atttgtacgt acatatatca taacgagtct gcaaggttta ttcaagcaaa aatcaaggtt
    50641 tcttgtgctc ataaggcata cggaacaggt tcaccaaatt ctggaaatcc ttgctcattc
    50701 cacgtaaagc attgcgcgtt cgcgtgccga ttaggattgt ctaacggatc ccctttttgg
    50761 ttcttctctg gtcgagcatg atagatcaaa atatcaaagc acccgtcttc tgaaaccgta
    50821 aacgagttgt gaccaggacc aaattgctta tttttttcag aagaaacgaa tactggctcc
    50881 gataatttat gccatgattc ttttaataaa agattcttgt gctcatcagc ccacagcagg
    50941 cccatggcat agttttcatc tgttgcacta ccagaatacg taatgaatat tttcccattg
    51001 cgagtaagga ctgctggacc ttcatttact gaaaaacccc gtttttccca ttcatactca
    51061 ggtatagaaa ggaggatctg cttccccttt aacgtccaag gattatccat ttcggataga
    51121 taaagattag aattcccagt aatttcagga tcttgttggg cccacacata atatagcttt
    51181 ccttgagaag agaaagttgt tccgtctaaa ctgaaagttt cccttttcgt ttttatttgt
    51241 cccttttcta tccaatctgt attcattgga tctatatgct gattttcaag tacgaacatg
    51301 cggtgatgat gagattcatc acgtatagtt ttatgattgc ttgcagcaaa gtaaatatac
    51361 cattttccat tgatataatg gacttcaggt gcccagatca attcactcat cggtccttct
    51421 tcatgagcct gccatacaat caggcttgca gcatgttcta attcattcag tgactttgcc
    51481 cttcttaatt caatcacttg gtagcctgga accgatcctg taaaataata ataaccatct
    51541 gtatgtttat atacccaagg atctgcccgt tgccgaacga taggattatt ataaagtgtc
    51601 ttcatcataa caaatttcct cacattttct ttattctaat tacattccaa gagtattttt
    51661 ctatccctac atttaattcg tcatgttttt ctattgaaaa atagtttatt tcaggtttta
    51721 ttttttctgg ttcttcacgt gtatttttgt ccaacagatc gctactggtt aatgtgtagt
    51781 gctctccttg atctagcaaa ttgaaatcat gttcaatcgt tatcttttgt tgttcatttg
    51841 tgcgattgat caagaaaata gtcagctgat tgccgttatc tacgatcaca ctgtccacat
    51901 aaggaacatt ttttatcttt tcacaatcat aaacagggca aatgatttgt tgtttcaata
    51961 cttgaccttt agcatatttc gataagtgtt gcatcacata ataagttgga ttcctccatg
    52021 cttgtccttt agcatctgtc agtattaaag gtattgtgtt tactaacaat gattgacaac
    52081 taatctttac gcgatctgcg tgtcgtaaaa tagccagccc taatgaacca aataataatg
    52141 tatcttccat agtaaagtaa caccaatcga tgggactacc gacttcaaaa tccctatgtc
    52201 ttttttccgg ttgggcatgt acattccatt catcaaacgc tagatacatt gttttctcac
    52261 ttctcaaata tccttttaca taatcacaag tagcaacgat ttcttcaatt tgacgatcga
    52321 atcgataagc ttttgcaagg tatgtcgctg tatcatcacg ctcattttta ggaggtttag
    52381 tcaagtcttc ttcatcatac ttatcaatat agttatgcaa agctaaataa tctacattct
    52441 cataagcttc ttctaatgcg atacgatccc attcagggta cgatggtaaa cgtggcgtag
    52501 agcttccaac taagattgtt tcaattgaat catccactaa cttcatgact tttgaggctt
    52561 catttgctaa cctaccatat tcataagcac tcttagcccc cacttgccat ggaccgtcta
    52621 gctcattccc taaacaccat aatttaacgc caaaaggctt tttttgccca ttttttattc
    52681 ttaaatcact ccagaaggtt ccttttggaa aattacaata ttctactaaa ttttttgctt
    52741 catcaattcc ttttgttcct aaattcaccg tgaatatcgg tttcgcttgt acatgactga
    52801 tccatttaaa aaattcgtgg agtccaaaag aatttggttc tatacctcgc catgctaaat
    52861 caattttttt tggtcgttgt tctttcctac ctacagtatc cacccaatca taaccagatg
    52921 taaagtttcc tccaggatag cgaatgacac ctaattctaa ttcctttaca taagagagga
    52981 catcttgtct aaacccgtca ccatcagctg tttcatggcc cggttcataa atccctgtat
    53041 agacgacact tcccatatgc tcaacaaatg agccaaacag ccgagaactg atctctccta
    53101 ccgtaaaatc ctctctgatt tttactttca cttcttcgtc caacagcttt ccctaccttt
    53161 catttcctat agtcaagata atagatacaa gtttccatac gccaccagca aagataaaaa
    53221 taaaaggagg gaaaagaaat atgagcagta caaatcctaa taacaatacg caacaaagaa
    53281 tatttctcaa aaaatcaaaa aatactttcc atgcactttg ttcaaaaatt tgtaaaaatg
    53341 tgatatcttt gttttcagaa atcacatata tccaggataa aagaaacatg gaataaataa
    53401 gtaaaactac atatccacta attgaaagta cgattgtctg ttcttctaat aattgattaa
    53461 caagaaaata aataatgatc gttaacagac taaggaacaa gttcttacca aaatgttgct
    53521 ttattccttg aaagaaaaaa taaatgatat ttcctgatcc ctcacctttc cattgcgcca
    53581 ttacataaaa aacagcacat gtagcaggca cgatagtaat aacaggcaaa cacacgatta
    53641 cccagagaat acctaataag atgtaatcag aaaccacaat caactgtcca taaagtttag
    53701 tctcaactat tttcatcttc ctcactcttt cattccagac atagctgttc cttgaacaaa
    53761 atatttctgt gcaaaaatat aaaccactag taatggcagc attgaaataa ccgttccagc
    53821 cattacaggt ccataaaaag aaatgttctg ccctgtaaat aaagctaacc ctgctggtaa
    53881 agttctcatt tttgaactac ttgtcaatat caatggataa agcaagtcat tccaactatt
    53941 catcagcgtg aaaatcccta atgataaaag agtaggtttg ctcaatggca acatgatttt
    54001 caaaaaaata ttaaactcac ttaatccatc aatgcgtgct gcctcttcca aagaatctgg
    54061 taaagtaata aaaaaggaac gcatcatgaa gataccaaat gcagttgtca tacgaggaat
    54121 gatcaaacct gcataagtat caagcatgcc aagcaaattg acttcaataa atagaggaat
    54181 catgaagact tggaatggga tcatcattgt cagcaaaacg aaatagaaca aaactgattt
    54241 tcctttgaaa cgcatacgag caaatgcata ccccgcaaga gaatcaaaga atacagaagt
    54301 gatcactgtc cctccagcaa aaatcactgt atttttgatg taatctaata aagggatcgt
    54361 tgtccaaacc ttaatatagt tatctagggt atagctatct gcaaatattc taggcggaaa
    54421 tgagataatg tctttttcgt gtttaaaaga agaaataatc agccacaaaa aaggaaacgc
    54481 aataaccaac aatataacta gcatactaat cgttcgaatg atttttttac cactaactgc
    54541 ttttcgacta ttcacagtaa ctgtaatcga gctttctggt gccatacagg tttccctcct
    54601 atttcatttg tttttctttc cgtgacatgt acacattagt ggagatagct atagttgcaa
    54661 caatgataaa caaaaccgaa gacagtgctg atgcatagcc caattcataa ggtgctgtaa
    54721 atcctcgact gtaaatatat tgaacagctg tttctgtctt aaattgtggg ccaccagcgg
    54781 ttgcaacata tacttggtca aacacttgca tcgaaccaat cagattcgtt aaaatacaaa
    54841 aacctaagga gggaacgatc tgaggtagcg taatgttaaa aaactgctgt cgatttgttg
    54901 caccatccat ttgagcagat tcatacaaag agggagagat tccctgaata gcagtcaaga
    54961 gaatcgtcat agtaacacca aaattcttcc aaacagtcat gatggctacc gtcggcatag
    55021 caagggttgg atcgcgaaaa aattgaggga tcggcaagcc gacttgtgaa aacaagtaag
    55081 gaatcgcccc tacattcgga tcaagcaaca tagaaaaaat aatcgcaatt gacgtcaatg
    55141 aacaaataac tggaatgtaa aatgtcgaac gacaaaaacg attgaatctg gtatttttag
    55201 ataatgctac tgctgctaat aaaccaacga taatttgtgt tggcgtttcg agtacggtga
    55261 aatataaaga atgaatcaac gaattaactg ctcgttcatc actaaatata cgtgtgaaat
    55321 tttcaaaact tacaaaattt cttgatgtaa agaaaatatt caaatctgta aaactaatag
    55381 caaatgttcc taaaagcggt atgacagtaa ataataataa aactaaaaaa gatggagtta
    55441 aaaacaaata cgcagcacga tcaggacgat tccaatattt ggtgaatccg ttcatatagt
    55501 ccacctcatc tttcattttg ataaaatata caatcttggt ttaaacgaat ctgaataaga
    55561 tatccgaaca atcgctgtga tttttgcaat aacacctatc tgcaaatact aggtcgatca
    55621 ttcagatatc tgtatcttgc caacagtcta tcctgtataa agttctgtac tatttttgca
    55681 gtaattgatt gatggcatca tctgcatcgt tcatgagtgt ctcaggatct tctcctgcta
    55741 ataatttttc aatcagtgga ttgatgatat cgttattgat cgcagagatt tgggtaaaac
    55801 ctggtaaata tggctctgca tagtccattt gtttcgataa ttcagataca ataggatcat
    55861 tttttacttc ttcatctttt gctactgaat ccaagtaggc aggaaaacca ttttcgatac
    55921 tccatttttt accaatttca gttgtattcc aatatttcaa aaactcatag acagcttctt
    55981 ttttattatt atctgtactt gccggaatgg catatcctac gccatctaaa atagctgttt
    56041 ttttgtctga atcactccct tgtggtaagg tagtcacatt ataatcaatc tcgtttgctt
    56101 tcaatccgtt atttaaccat ggcccattga tttcaatggc tagttgacca gcattcatta
    56161 aattgtccat ttcggcgcca gaaatcgatt ctggaccagt cttgtctaca tggatcattt
    56221 tttggatcgc ttttaacgtt ttaaggttct caggagacgc aaattcagac ttagtataat
    56281 catcgttcac taatttaccg ccatttgcta acatccagtt atataacggt gcagttccat
    56341 ccttattgaa gacaaaacct gatacatttt tactactatc agttaatttt ggtgccattt
    56401 ctgtcaattc ttcccaagta gtaggtggtt gttcagtatc taatccagct tgtttaaaca
    56461 aatcattatt ccaatacata tacatgcctt gtacctgcat ggggacaaaa tactgtttac
    56521 cttctacttc acctaattca atagccgttt ctttaaaatc agatttatct actccatcat
    56581 attcccagaa atcgtctaat ggttgtaccg ctccgttttc tacatactgt gcaaaatctg
    56641 gataatttaa tgcaataaag tcaggtgctt ttttagaaga aatcgctgta ggaagttttt
    56701 cattcaaatt ggcccaagtc atgatatcca tttcaatttt gatgttttta tcatttgttt
    56761 tattaaattc attaacgatt tcttgcaata tttcaccatc agatgcagta aacccattcc
    56821 aaaaagtcaa agtcacttct ttatcagaat cagattctgc tgaacttccg ccaccgcaag
    56881 ctcctaaaat acctgttgca gctaccaaca aagagccaat taaccatttt ttacctttca
    56941 ttttttgttc ctccttcatc tgataaacga catctgacca cattccaaga tagcggtttc
    57001 aataaacaat tgattttccc atcttcagct tttacatttg ttgaatgact tggttttact
    57061 tgttcacttt taggaagatt agttgctttt gtatcaaatc cactcatttc agaaaaatca
    57121 atcactccct ctaatgataa ttcagacaag tgaacagtta gattcatttc ttcttctcca
    57181 cggttaactg caaatatgac aagttctttg tcatttatta cggctatact ttctaaatac
    57241 ggcacttctt caaaatcttc cgtcgcatag tttgctgaac gaatttgtgg gcttaacacc
    57301 tctccttgtc catacacagc agcttgcata aatggataat agatcgtctg tctccaagct
    57361 tctccgtttg tttctgtcct gattggtgca ataacattta ccaattgagc aagacaagca
    57421 atctttactc tatctgcatg tttcaataaa gtgattaata gacagcctaa tagtaatgca
    57481 tcttcaaaat tatagttatc ttctagtaaa ggaggagcaa tctgccaagg cgctgcttgc
    57541 tcatcttgtt ccgctgaatg ataccaaata ttccattcat caaaggacag gttgatctgc
    57601 ttcttactat gtttcttcgc cttgactgta tcgcacatcg ctgtcacttc agaaatgaac
    57661 cgatccatgt ctaaggaacg tgcaagataa tgagaaagat catttttttg gttgccataa
    57721 tattgatgca gagacaaata atctatttga tcgtacgctt gatcaagaac tgttaactcc
    57781 caatcaccaa atgtaggcat ttgccgattc gaacttccgc ataaaaccac ctcaattgaa
    57841 tcatctacga gtttcatcgc cttagccgtt tcctctgcta accgtccata ttcttccgct
    57901 gttttatgtc caatctgcca aggaccgtcc atttcattcc ctaaacacca tgtcttaatt
    57961 ccaaaagggc tctcttgacc attcgaacgc cttaaatcac tccaataagt tcctttagga
    58021 aaattacaat attcgactaa attacgagct gcatctactc cacgagtacc cagattgaca
    58081 gccatattga tttcggcccc cacatgctga caccagttat aaaattcatg aatcccaact
    58141 tcattcgttt caattgtccg ccaagctaaa tccaaccttc taggtctatt tgctatgggc
    58201 ccaatactgt cttcccaacg aaatcctgac acaaaatttc caccaggata tctaatcatg
    58261 ggaatgttca attcttttac caagtgaatg acgtcttggc gaaatccact tttattagct
    58321 gatggatgat ctggctgata aatcccttca tatactgctc gtcccatatg ttcaataaat
    58381 gaactgtaca accgcggatc aactttgcct acacgcttga cactactaat caacattgtg
    58441 gcttccataa ctgacctcct ttaatttata catgaataat acacctcgtt gaaagcgttg
    58501 tcaataatat aaatgttaaa cttacttatt ttttatcgat tttaattaac caaaatatta
    58561 ataatgatta aaacaaataa tttaatataa cttttattaa caaatatgtt aatatataag
    58621 aaaaaccttt taagaggtga tatatatgca actacaaata aacgaagaat ccttaccggt
    58681 atatgaagca ttagctagta aaacaaggat caagatcatc cagctacttt ccaaaaaaaa
    58741 gatgaatgtc aaagatttgg caaaagaact tggagtgagc agtgctatca cgacgatgca
    58801 cgtgaaaaag ctagaggaag caaacatcat caaaacagaa aaagtaggac aacaaaaaat
    58861 ttcgagcctt cgtgtcgata aaatcgatat cagttttcca gaaaaaatat tcaatgcttt
    58921 tgatacgaaa gaaacatcga tacctattgg tcactataca aattatgcaa ttgaaccaac
    58981 atgcggttta gctacgatcc atgattttat cgggaaagtg gatgaaccac gctattttat
    59041 ggatcctcga aggatggatg cccgcattct ctggtttacc agcggatttg tcgagtatca
    59101 ggcacctaat tttttaaata cagaggatac attggagatg ttggaagttt ctgtggaaat
    59161 ttcttctgaa tttccttttt caaatgacaa ttggccttca gatatcactt tcagcctaaa
    59221 tggtgtggag ctaggaacat ggacgagccc tggagatttt gctgatatcc gcggtaaata
    59281 tacgcctgat tggtatccag ataatcttaa tcaatacggc ttgctgaaga cgatccgaat
    59341 taccaaacac ttgacgaata tgaatggaga acccttgtca aacatcacga tcaacgacat
    59401 ccctaaagag caagacactt ggcatttgcg aatcgaagtg aaagacgatg ccaaacatgt
    59461 ggggggctgt actttatttg gtaaaggatt cggtaattac gatcaggata tcaaattaaa
    59521 agtttactac agctgatatt tttcttttct attttataaa acaaaaacag ccaatcccta
    59581 tgaagggacg gctgtttttg ctttattgtt atttccagaa atcatccaaa acggaaattg
    59641 gcaaatgtcg tttatgttgt gtcttgttcc accatgcttc gattttttct tgtgcttgag
    59701 cgggaacttc ttttccttct agataatcat caatttcatt atatgtgaca cctagtgcga
    59761 cttcatctgc aatcattggt ttcccatctt caagatctgc agtcggaatt tttgtgtata
    59821 atttttccgg tgcattcaat gcttgaagca attgtttccc ttgtcgtttg tccaaacgga
    59881 ataatggcaa aatgtcggct ccaccatcac caaatttcgt gaagaatcca gtaatgtttt
    59941 ctgcagcatg atctgtccct aatacggctc ctgctctttc tccagctacg gcatattgcg
    60001 taatcatacg ttgacgtgct ttgatatttc ctttgttaaa atcgctgatt cccacacctg
    60061 cttcgcttaa tacttgtact tgtgcatcaa cagctggttt gatatttact cgcagactaa
    60121 catcgggctg gataaagtca agagcagctt ttgcatcttc ttcatctgct tgttcaccat
    60181 aaggaagacg aacagcgata aattgatagt tttcatcttt tgtttcttca cgcatttctt
    60241 ccatcgttag ttgcgccaaa cggcctgcta aagtagaatc ttggccgccg ctgataccta
    60301 gtacaaaagt tttaagaaac ggatattttt tcaaatatgc tttcataaag tcaatacttt
    60361 tacgtatttc ttcttttgga tcaattgttg gtttgacacc taattcattg ataatttctg
    60421 tctgcaggct catttattct cctcctatgc ttctgtatga agttctgcta cgcttttttt
    60481 cattcgttcc atgatagcca ttttatggtt ccagcattca gtagacagat cgactgggta
    60541 tttttgcgga ttcaagtctc gtttatactc ttcccatagt gaatctagat tttcttttgt
    60601 atattctttg atttcgttta gtgcaggtaa ttcgtaaact ctttttcctt cgataaagat
    60661 atcttgtaaa actgggcgag ctgtaaagtc tcgaacagtt ttattgataa acgtatgcac
    60721 tggatggaac atgaagatag cttcttcttc tcgagggtct tcatcccata atgtcacgta
    60781 gtctccttca gatttcccat caaaatttcg agtgatgcgc cacacttgtt ttttccctgg
    60841 agtagttact ttttctgcat tgcttgataa cttgatcgta tccatcattt ttccttcatc
    60901 atcttcgatc gatactagct tgaatactgc accaagggct ggctgatcat aggctgtgat
    60961 caattttgtc ccaacacccc atacatcaat tttagctttt tgcatcttta aattcaaaat
    61021 cgttgcttca tccaagtcat tcgaagcata gatttttgct tccgtaaatc cggctgcatc
    61081 taattgttcc cgaacacgct tagatatata ggccatatct ccactgtcga tgcgtacgcc
    61141 ttggaagttg attttgtcac ctaattcttt cgccacgcga atcgcacttg gcacacctga
    61201 tttcaacgta tcataagtgt cgactaagaa cacgcagtct ttatgggttt tagcgtaggc
    61261 cataaatgct tcataatcat ttccataaga ttggactaac gaatgagcat gggtcccgct
    61321 agctggtatc ccaaatatct tcccagcacg tacattgctt gttgcatctg ctccgccgat
    61381 atatgccgct ctagttcccc agactgctgc atccagttct tgtgcccgtc tagttccaaa
    61441 ttccaatagt ggatcttctc cgatgacaga tttgatacga gctgcttttg tcgcgatcaa
    61501 cgtttggaaa ttgaccatat tcaacagtgc tgtttctact aattggcagt gcgctaaagg
    61561 cccttccact tggattaatg gttcatttgc aaaaactagt tctccttcac gagcagaacg
    61621 aactgttgct ttaaattcaa aattttgtaa atactccaaa aaaccttcag gatagacttc
    61681 taatccacgc aagtaagcaa tatcggaatc attgaacgtc agattctcta aataattgac
    61741 taaccgttcc aatcctgcaa aaaccgcgta tccgtggtta aaaggcattt ctcgaaagta
    61801 acattcaaaa acagcatgta aatcagctcg acctaattcc cagtatgtct gcatcatatt
    61861 gatttgatat agatccgtat gcagcgtcaa actgtcgtct gggtaagtat tattcatctt
    61921 gtattactcc tcttggcaag ttttcatttc ctacccatta taacaaaaaa aattaatagg
    61981 aaaagaaatc ttccattttt tctgaaaaag cacatgtttt acggatattt cttgctaaaa
    62041 atgaactcca tctgctaaaa ctatcctttc ttattggtat ttaacctaaa cgagaaagaa
    62101 tacttatttt attcaatgta tccgagacac gaagaaatta gcgttttcta tttttcttac
    62161 ttgataaaat aagtagattt tcctactaca atcgtagccg ttaagatacc gatgattgaa
    62221 caaatataac caaatgtctc tacaacataa tcaatggcaa aagtttttga agcaataata
    62281 cgtctttcct tttttgcttc ttatccccaa agaaacggat ataacttatt atgtattgaa
    62341 tttttttgga aaggcgaatt atgacaagat ataccttgcg ttgaaaaaac tcgcggaaaa
    62401 aatatcacac gtttttaaaa agatacaaag taagaaagca gctgtcaata gaatggaaac
    62461 aaaaatggcg agacatcaat cagtctcgcc ttgtttttta ttgtatacat tagatatgga
    62521 gcaggttacc ataaagatga ttattagtcg ttattaaata gaatccttcg tatttttttg
    62581 ttctatcact acaatatctt tatttggacg tttgaattgt attccggcac gttctagctc
    62641 ctgtttcact cctacatgga ctttgacatc ttctcgtgtc atttttaaaa cgtgatgaat
    62701 cgcatagtcg atttcttgcc ttgtgatttt tttcttcgta ttgatcatca cgacttgctt
    62761 tttatcatat gtgtctacca atagcagttg tgttcgatct aacgaaaata atttgtaata
    62821 attaatagcc gtattcccaa aaaagaattc cactacttta ggataaaatg tcttaatatt
    62881 taaattacta ttcacaggtg tttcgattag cttcatctca ttcctctttt ctatatagtc
    62941 gatttagatc caatcttaag ttatgttacc atctttccta gcattaagga atcggttaca
    63001 attgaacctt taaagacaaa aggatttacc ttttatcact taatagtata acataatttc
    63061 gtgagaaaaa aatacaattt tttcttgacc atctcgttac gtaaaggatt atgcttacat
    63121 ttgtcaggag gaaaaataat ggagtacaca ataaagaaaa tgtcagagat atcaggagtc
    63181 agtccgagaa ccttgcgctt ttatgatgag attggactgc taaaaccagc taggatcaat
    63241 tcttcaggtt atcggattta tggcaaaaaa gaagtcgatc gtctgcaaca catcttattt
    63301 tatcgaacaa tggcattcaa gttggatgat atccaagagg tcttagacaa tccatctttt
    63361 gaccaccaga aagctttaat caagcatcag caaatgttgc tggaaaaacg ggcacaaatc
    63421 gataccctct tgacaactgt ccaacagaca cttgatatgt acgaaggagg aagaaaaatg
    63481 agtgacaaag aaaaatttga agggtttaaa caacaaaagt tgaaagaaaa tgaagaatcc
    63541 tatggacaag agattcgaca aaaatacgga aaaaaaaagg ttacagcatc caatgaaaaa
    63601 tggatgaata tggataaaga aacgtatgaa gaaatgcaaa ctgttgaaaa gcagatgtta
    63661 tttgatctca ctctttactt aaaagaacca gaagatgaaa gcttagcaga ccgtatcttc
    63721 caagctcata agaagtggtt ctcttacagc tggcctgaat atcagccaaa agcgcataaa
    63781 ggactaggaa tgatgtacga agccgatgaa cggttcactg catattatga cgagcgaagt
    63841 ggtcatggtg cagcaaaagc tttaaatgaa attatccaaa aaaaggcgta atcttttaca
    63901 tgatccaaca aaaaagtaca cgtaaaatga cctaataaca aaacagcaga cacccaagtt
    63961 agatttttat gctaactttt ggtgtctgct ccattctttc acaagttttt tcatcctact
    64021 ttaaatatat tcatcgttga ataaacgtat aaggtatttt cactttatcc tttttttctg
    64081 taagaaacaa ttgaaatgcc atttctccgc aagcttccag atggtggtcg atggttggga
    64141 aaccaagaag ctcgctgatc agcaaattat cgcgtccaat caccactggt gtcttatctt
    64201 gcagatagct ttgcaagatg cctgctgcaa ccatatccga atttgtaaag acaccatcaa
    64261 ctccaagctc tttaaaaaag aagcctgctt gttttccttt ctctgcatct atacaatccc
    64321 aaaaaacaag tgattcatca aaagatggaa aaagttgatg acatagctgc aaagtgattt
    64381 ttgagttata acttagcctg ccacttcgcc ccaacgtgat gcccaattgc tttatacctt
    64441 gctgcttcaa ataagtaaga ccttctgtaa ttgattgttc tcgatcaata aagacacagc
    64501 ttgcctgttt tcccttgatt tcttcacaaa aaactagagg tccatatttt tgatatgcca
    64561 ataaatcatc tagtgtattg gcacgagacg taatgatcaa tccatcgaaa gctttagctg
    64621 caaattcttc aagatacctt cgctcttttt ctttatgata gcccgtcggt aaaagtgtca
    64681 ctttgtaatc ataatcaaac gctgcttcaa tgatcccact gatcaactga tcaaaatacg
    64741 gatgattggt ataaggcaga atcactccaa tgcttttcgt ttttccataa cttaactgtc
    64801 tggcatttgc attagggata taatcgactt ctttcatgac cgcaagtatt tctttccttt
    64861 tttcctcatc tacatatgga tgtccattga ttacacgtga aatagtagaa actgaataac
    64921 ctgtgagctt tgcgatatct cgaatgtttg ccactgctgc ttcgccacct atacaaaaag
    64981 attttcttgt aaatagtcta ccacagctgg accgcattca aaaaactgat acatttttcc
    65041 ttcatgcgaa aaactgatcc gctgcccgcc ccaatatata tcttttgtca aattttcgat
    65101 ttcattcatt ggtatttctt ttactatatt cctattcaac ccttgaaaac tgtacaacgt
    65161 taatacggat cccttgaact cgacaaacgc ataaaaataa ttgttcgttg tgccatctgt
    65221 tatctctaca taagtattca ttgcaagccc tccttttgat actttgagta tagtgtatga
    65281 aacgcgtctc atagcaagga gtttgttttg ccaaagaaaa gttttattcc tctttcatta
    65341 ttaccaaagt ctcttatttt aaattgaata cattataatg atactgtaaa tatatcttta
    65401 ttattagtga at
//
LOCUS       DACDLM010000007        63746 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.007, whole genome shotgun sequence.
ACCESSION   DACDLM010000007 DACDLM010000000
VERSION     DACDLM010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 63746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63746
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.007"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..211)
                     /locus_tag="IV356_000466"
     CDS             complement(<1..211)
                     /locus_tag="IV356_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP9014187.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADL"
     gene            443..622
                     /locus_tag="IV356_000467"
                     /pseudo
     CDS             443..622
                     /locus_tag="IV356_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            621..1139
                     /locus_tag="IV356_000468"
     CDS             621..1139
                     /locus_tag="IV356_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002414673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014188.1"
                     /translation="MSIEELVCGNVEEYILGIILYRDSIVLDGITFPDKNLFQHLRQQ
                     FPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNILKIEELFINAIVEE
                     FDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDNINKLEQTISSIGKK
                     YTKKKMKGGDTI"
     gene            1178..2320
                     /locus_tag="IV356_000469"
     CDS             1178..2320
                     /locus_tag="IV356_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP9014189.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(2415..3806)
                     /gene="sufB"
                     /locus_tag="IV356_000470"
     CDS             complement(2415..3806)
                     /gene="sufB"
                     /locus_tag="IV356_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HAP9014190.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(3811..4281)
                     /locus_tag="IV356_000471"
     CDS             complement(3811..4281)
                     /locus_tag="IV356_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HAP9014191.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(4268..5503)
                     /locus_tag="IV356_000472"
     CDS             complement(4268..5503)
                     /locus_tag="IV356_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAP9014192.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(5500..6786)
                     /gene="sufD"
                     /locus_tag="IV356_000473"
     CDS             complement(5500..6786)
                     /gene="sufD"
                     /locus_tag="IV356_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HAP9014193.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(6799..7572)
                     /gene="sufC"
                     /locus_tag="IV356_000474"
     CDS             complement(6799..7572)
                     /gene="sufC"
                     /locus_tag="IV356_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HAP9014194.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(7769..8617)
                     /locus_tag="IV356_000475"
     CDS             complement(7769..8617)
                     /locus_tag="IV356_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP9014195.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(8641..9327)
                     /locus_tag="IV356_000476"
     CDS             complement(8641..9327)
                     /locus_tag="IV356_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9014196.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(9320..10354)
                     /locus_tag="IV356_000477"
     CDS             complement(9320..10354)
                     /locus_tag="IV356_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP9014197.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            complement(10749..11087)
                     /locus_tag="IV356_000478"
     CDS             complement(10749..11087)
                     /locus_tag="IV356_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HAP9014198.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(11089..11445)
                     /locus_tag="IV356_000479"
     CDS             complement(11089..11445)
                     /locus_tag="IV356_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HAP9014199.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(11451..12638)
                     /locus_tag="IV356_000480"
     CDS             complement(11451..12638)
                     /locus_tag="IV356_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAP9014200.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(12829..13674)
                     /locus_tag="IV356_000481"
     CDS             complement(12829..13674)
                     /locus_tag="IV356_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP9014201.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            13908..14873
                     /locus_tag="IV356_000482"
     CDS             13908..14873
                     /locus_tag="IV356_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HAP9014202.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            15250..16293
                     /locus_tag="IV356_000483"
     CDS             15250..16293
                     /locus_tag="IV356_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HAP9014203.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(16355..16819)
                     /locus_tag="IV356_000484"
     CDS             complement(16355..16819)
                     /locus_tag="IV356_000484"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HAP9014204.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            17065..18012
                     /locus_tag="IV356_000485"
     CDS             17065..18012
                     /locus_tag="IV356_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP9014205.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(18223..20295)
                     /locus_tag="IV356_000486"
     CDS             complement(18223..20295)
                     /locus_tag="IV356_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP9014206.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(20228..20605)
                     /locus_tag="IV356_000487"
     CDS             complement(20228..20605)
                     /locus_tag="IV356_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HAP9014207.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(20734..21294)
                     /locus_tag="IV356_000488"
     CDS             complement(20734..21294)
                     /locus_tag="IV356_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP9014208.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            21444..22736
                     /locus_tag="IV356_000489"
                     /pseudo
     CDS             21444..22736
                     /locus_tag="IV356_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
     gene            complement(22796..23914)
                     /locus_tag="IV356_000490"
     CDS             complement(22796..23914)
                     /locus_tag="IV356_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HAP9014209.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(23928..25349)
                     /gene="arcD"
                     /locus_tag="IV356_000491"
     CDS             complement(23928..25349)
                     /gene="arcD"
                     /locus_tag="IV356_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HAP9014210.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(25595..26716)
                     /gene="mnmA"
                     /locus_tag="IV356_000492"
     CDS             complement(25595..26716)
                     /gene="mnmA"
                     /locus_tag="IV356_000492"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HAP9014211.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            27120..27719
                     /locus_tag="IV356_000493"
     CDS             27120..27719
                     /locus_tag="IV356_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphatase"
                     /protein_id="HAP9014212.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(27857..29143)
                     /gene="efmA"
                     /locus_tag="IV356_000494"
     CDS             complement(27857..29143)
                     /gene="efmA"
                     /locus_tag="IV356_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HAP9014213.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(29414..29758)
                     /locus_tag="IV356_000495"
     CDS             complement(29414..29758)
                     /locus_tag="IV356_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HAP9014214.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(29895..31031)
                     /locus_tag="IV356_000496"
     CDS             complement(29895..31031)
                     /locus_tag="IV356_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAP9014215.1"
                     /translation="MKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGRHAH
                     EKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIEHPA
                     VLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPIK
                     EIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKRDGV
                     NIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLILDTL
                     EANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNIEPS
                     HVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(31220..32194)
                     /locus_tag="IV356_000497"
     CDS             complement(31220..32194)
                     /locus_tag="IV356_000497"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAP9014216.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(32274..33149)
                     /locus_tag="IV356_000498"
     CDS             complement(32274..33149)
                     /locus_tag="IV356_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HAP9014217.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            33279..35186
                     /locus_tag="IV356_000499"
     CDS             33279..35186
                     /locus_tag="IV356_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HAP9014218.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(35727..39005)
                     /locus_tag="IV356_000500"
     CDS             complement(35727..39005)
                     /locus_tag="IV356_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HAP9014219.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(39276..39821)
                     /locus_tag="IV356_000501"
     CDS             complement(39276..39821)
                     /locus_tag="IV356_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP9014220.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(39833..40525)
                     /locus_tag="IV356_000502"
     CDS             complement(39833..40525)
                     /locus_tag="IV356_000502"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HAP9014221.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(40544..40828)
                     /locus_tag="IV356_000503"
     CDS             complement(40544..40828)
                     /locus_tag="IV356_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014222.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(40841..41404)
                     /locus_tag="IV356_000504"
     CDS             complement(40841..41404)
                     /locus_tag="IV356_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAP9014223.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            41632..42294
                     /locus_tag="IV356_000505"
     CDS             41632..42294
                     /locus_tag="IV356_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     protein"
                     /protein_id="HAP9014224.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            42418..43614
                     /locus_tag="IV356_000506"
     CDS             42418..43614
                     /locus_tag="IV356_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HAP9014225.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(43715..45091)
                     /locus_tag="IV356_000507"
     CDS             complement(43715..45091)
                     /locus_tag="IV356_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP9014226.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(45128..45994)
                     /locus_tag="IV356_000508"
     CDS             complement(45128..45994)
                     /locus_tag="IV356_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HAP9014227.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(46083..47108)
                     /locus_tag="IV356_000509"
     CDS             complement(46083..47108)
                     /locus_tag="IV356_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP9014228.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(47126..47800)
                     /locus_tag="IV356_000510"
     CDS             complement(47126..47800)
                     /locus_tag="IV356_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP9014229.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(47984..48877)
                     /locus_tag="IV356_000511"
     CDS             complement(47984..48877)
                     /locus_tag="IV356_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP9014230.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(48951..50648)
                     /locus_tag="IV356_000512"
     CDS             complement(48951..50648)
                     /locus_tag="IV356_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAP9014231.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(50641..51954)
                     /locus_tag="IV356_000513"
     CDS             complement(50641..51954)
                     /locus_tag="IV356_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAP9014232.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(51954..55991)
                     /locus_tag="IV356_000514"
     CDS             complement(51954..55991)
                     /locus_tag="IV356_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAP9014233.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FYHNSTAINNHEQISSDIFPLTNDINRLTGSENTAINRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(56004..56462)
                     /locus_tag="IV356_000515"
     CDS             complement(56004..56462)
                     /locus_tag="IV356_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP9014234.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(56760..57278)
                     /locus_tag="IV356_000516"
     CDS             complement(56760..57278)
                     /locus_tag="IV356_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAP9014235.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(57280..57897)
                     /locus_tag="IV356_000517"
     CDS             complement(57280..57897)
                     /locus_tag="IV356_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HAP9014236.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKFGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(57894..58748)
                     /locus_tag="IV356_000518"
     CDS             complement(57894..58748)
                     /locus_tag="IV356_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP9014237.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(58745..59656)
                     /locus_tag="IV356_000519"
     CDS             complement(58745..59656)
                     /locus_tag="IV356_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP9014238.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(59697..61031)
                     /locus_tag="IV356_000520"
     CDS             complement(59697..61031)
                     /locus_tag="IV356_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP9014239.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            61239..62069
                     /locus_tag="IV356_000521"
     CDS             61239..62069
                     /locus_tag="IV356_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HAP9014240.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(62313..62562)
                     /locus_tag="IV356_000522"
                     /pseudo
     CDS             complement(62313..62562)
                     /locus_tag="IV356_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(62753..62947)
                     /locus_tag="IV356_000523"
     CDS             complement(62753..62947)
                     /locus_tag="IV356_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014241.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(63452..63637)
                     /locus_tag="IV356_000524"
     CDS             complement(63452..63637)
                     /locus_tag="IV356_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014242.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
BASE COUNT        18257 a        13559 c        11446 g        20484 t
ORIGIN      
        1 ccaaatcagc aattcgggat aatcgctctg gtattggtaa ataggttccc ttctcccatt
       61 cgtagatagt ctttttgtca attaattgac cgttgttaat cataagacca aatgctggtt
      121 gtgttaattt tttactcttt cttatagctt ttatttttgt tccgagtatc ttttttcgtt
      181 ctaaataatt tattggtgga cgttttatca tattgaccac acctcctaaa attagtatac
      241 ctcaaaaaag gggtgttgta aataaatttt acaaaactat tgacacccct tttttatcga
      301 ggtattatgt gtatgtcgat gaactggtaa tcattttttg tttgattaat cggttaataa
      361 caaaatactt ttattttgag caaaaaatac gaagataatt cttagaaaat ttgttcaagc
      421 aatcacgaaa ggagggggaa atatgtctct acaaatcatt gatagcattg tttctataca
      481 agttgaacaa caagtgaaag agataattac agtgctaaag cctatgctag aagacattat
      541 ttctggagtc actctagagt atatggacta tcagcaggca agtgaatatc taggtgtatc
      601 agtaggaacg attagaaaat atgagtatag aggagttagt ttgtggcaat gtagaagaat
      661 atattttggg aattattctt tatagagata gcattgtact agatggtata acatttccag
      721 ataaaaacct gttccagcat cttcgtcaac agttcccacc agtacactct aatttagata
      781 catggctgga tagatattcc aaattagaac cagagatgca agaatttatt gctaacaaga
      841 cttgtaataa agttaaaaat gaaaaaatta gtcttttcaa tatcttaaaa atagaagaat
      901 tattcatcaa tgctattgta gaagaatttg acaataacat tcttttcctc actagcagta
      961 tagaagaact actagaaaga atggtagatg aatggctacc tattcaattg aaagacatgt
     1021 cttatcccga agaagctgtg agagaaatta ctgataatat aaacaagcta gaacaaacga
     1081 tttcatcaat tgggaaaaaa tacactaaga aaaaaatgaa gggaggtgat accatctagt
     1141 ggtaagtact ccttgtaaac taagaggaga tgatttcatg gcaaaaatat caaagtacaa
     1201 aaagaaaaac ggtcaagtgg cgtggatgta taaaggacac attgccaccg atccacgaac
     1261 tggtgaaaaa ataaatacta cgagaagagg ttttagtagc aaacaagaag ctcaaaaaga
     1321 ttatgacgag tacagacatc aaatattata cggtgttaaa aagaaagcac ctgatatgac
     1381 atttgaagac ctgtataatg aatggataac tcatcagcgt accagtgtta aagcttcaac
     1441 aatcgcaatc tcagtaagat acgcaaataa tcaaatactt ccagcatttg gtaagcttaa
     1501 actatcgaat atctctgtcc catattgtca aaaagtggta gatgaatggc acagtaaata
     1561 tgaaagttac gattatatga gaaaacagac tgcacaaatt ttacgctacg gggttgcaat
     1621 gcaatatatt gacaataatc ctatggaaaa aacacttctt ccacgaaaaa aagagtatga
     1681 gaaaaatcgt aaattttact caaaagagga gcttaataat ttactggatg cttttaaaga
     1741 ttttggtaac atgaaacaat acgccttctt cagattattg gcatacacag gtatgagaaa
     1801 gagtgaagta ctcgctttac agtggaaaga catagacacg tttaataaag aactacatgt
     1861 caataaaact cttgctgtag atgaatttgg taaagttata attcaatctc cgaaaacaag
     1921 agcttctaga cgagttatct ctttagatac tgagactctt tctatcctca acaactggaa
     1981 attacagcaa aaagaagagt atttaaaact tggatacaat actagctcta aagagcaaca
     2041 tgtttttaca acagttaaaa acactctata cattccaaac actgttaatg attggttaag
     2101 atatattttg aaaaaatata acttgcctcg tattacacct catgggttta gacatacaca
     2161 tgctagttta ttattagaag caggagaatc tgtcaaggta gttcaacaac gattagggca
     2221 tgaaaatagt aaagtgacat tagacatcta tgcacatatt acaaataatg cacctaagaa
     2281 aacaggtcaa gactttgctg atatgatggc tcatcagtaa aagagctggt caaaatctgg
     2341 tcatttctag tatacaggca aaacaaaaaa gctagaaccc ttatatatca agggttctag
     2401 ctcctataac aggtttaccc aacactgcct tccatctcat aactgatcaa tcgattgagt
     2461 tcgactgcat attccattgg aagttctttg gtgaatggtt caacaaagcc catgacgatc
     2521 atttcagttg cttcagattc ggtcaggcct cggctcatca gatagtagag ttgttcttct
     2581 gagatttttg agactttggc ttcgtgttct aaagagactt ggctgttgtg gatctcattg
     2641 aatgggatcg tatcggattt cgaccattcg tccatgatga tcgtgtcaca ttcgatatga
     2701 gagatcgaac ccgcactgtt tttggcaaag gttacttgtc ctcgatagtt tacttctccg
     2761 ccgtcttttg aaattgattt agagacgata gagctagatg tatttggtgc attgtggatc
     2821 atttttgcac ccgtatcttg gatttggttt gctcctgcaa aggcgatgga gagcatggtg
     2881 cctcgtgcac cttttccatc taagtaaaca cttgggtatt tcatcgttgt ttttgcacct
     2941 aggtttccgt cgatccattc aacggttgcg ccttcgtatg cttttgctcg tttggttact
     3001 aagttgtaca cattgtctga ccagttttgg atcgttgtgt aacggcaata cgcatctttt
     3061 cttgtaaaga tttctacgat ggcggcatgc aggctgttac ttgaataagt aggtgccgta
     3121 caaccttcga catagtggat gcttgctcct tcgtcaacaa tgatcagcgt acgttcgaat
     3181 tgccccgtgt tttccgcatt gatccggaag tacgtttgta atggaacatc gactttgacg
     3241 ccttttggca cgtaaataaa ggtcccacct gaccatacgg ctgaattcag cgctgctaat
     3301 ttgttgtcgg ttggcggtac aagttttgaa aagtactctt tgaataattc agggtattct
     3361 ttcaaagcag agtcagtgtc agtaaagacg attcctaact tttcgaattc atctttcata
     3421 ttatggtaca cgacttctga ttcatattgt gcggaagcac cggctagata agctcgttca
     3481 gcttctggta taccaatctt ttcaaatgta tctttgattt tttctggtac gtcttcccag
     3541 tcacgagcgg gtttgtcact tggtttttgg taatatttga tggcatcgaa atcgatgtct
     3601 gaaaggtcgg ggccccatgt ttgcattggc attttgttaa atgtttctag agatttcaga
     3661 cggaattcaa gcatccattc tggttcgcct ttgattcttg acatctcacg gatcacttct
     3721 tctgtcaagc cttctcctgt actgaaaacc ggttcgacat catcgtgaaa cccgaattta
     3781 tattcttcta attctggtac gcccatgttc tcactcctct tccttgtggt aatgatggaa
     3841 agctgcggta ccatcgtttt ccattgcttt tcctagtgct ttccaggcaa gtgtcgcaca
     3901 tttgatccga gcgggaaatt tagctacacc accaagcata gcagcatcgc ctaattggtc
     3961 gggatctttg acttcttttc cttggacaag ctgtagaaag tctacagtta aatgttctgc
     4021 ttcttctatt gattttccga tgacggcgtc tgtcatcatc gaggcacttg ccgtactgat
     4081 ggagcagcca ctgccgtcaa aggcgatatt tttgatgatt ccgtctttta catcgacttg
     4141 caattcgatc acatctccac atgtggggtt gttcaattcg atcttgcttg tcgagtcagt
     4201 caagcttcca cgatgatgcg gatgggaaga atgatccaag atcacttgac ggtataaatt
     4261 gtctaattta gatagtccca tgttggaaaa actcctttgt tgccatgatt gcttcaacta
     4321 aacggtcggc gtcttgcgtt gtgttgtaga aataaaagct cgcgcgagca gtcgctgata
     4381 cttcaaggta cttcaatagc ggttgcgcac aatgatgacc tgctctgacg gctacccctt
     4441 ccatgtctaa agctgtcgcg acatcatggg gatgtaaccc atccaaattg aatgcaacga
     4501 ctcctgtccg aaaattcggg tcttgtggac cataaacagt caatccatca attgcttgta
     4561 attttggcaa cacataagcg gctagttctt cttcatatcg atggatattg tccataccga
     4621 gtttttgcaa ataatcgatt gcatggccta atgcgatagc gccggcgata tttggtgtcc
     4681 ctgcttcgaa tttccaaggt agttctttcc atgtactgtc gtataattcg acaaaatcga
     4741 tcatttcgcc accaaattca acaggttcca tttcttctaa ccattttcgt ttaccatata
     4801 aaacaccaat acctgttggt ccgcacattt tgtgtccgct gaaagcaaag aaatcacagt
     4861 ctagtgcttg gacatcaatg gccatgtgcg gggcagattg agcaccatct actacgatga
     4921 ccccgccgtt ttcatggaca agttcagcta attcttgaac aggattgaag acacctaaga
     4981 cattggatac atgagcaatg gagacgattt tggttttgtc cgtaatcttt ttcgctgcat
     5041 cctccatatc caggaagcct tcttctgtta gttcgatata tttcaagaca gcacctgttc
     5101 gttttgccaa ctgctgccac gggataacat tagaatgatg ttccatgtaa gagagcacta
     5161 tctcgtctcc tgctttgata tagcggtcgc cgaaggttct ggctacccaa ttcaagcttg
     5221 tcgtcgtacc acgagtaaac agcacttctg ctgtttcttt tgcatggatg aacgcccgta
     5281 ctttttctct tgcttgttca taatcatggg tcgcgcgttc tgctaacgta tggacaccgc
     5341 gatgaacatt ggcgttatcg tgttcgtaat agtacgctaa tgcctggagt acttgttttg
     5401 gcttttgggt cgtcgctgca ttatccagat aaactaaagg ttcatcattg acgtcttgaa
     5461 ataagatagg aaaatcattg cgtagctttt tagcatcgat catccattca acttcccttc
     5521 gattacttcg actaattctt tccgaacttg ttctacaggg attgctgtta agacagaacc
     5581 gaggaatcct cgaatcacta agcgctctgc ttcttcttta tgcaatcctc tactcatcag
     5641 atagtacatt tcttctggat caactcgtcc tacactggca gcatgtccag cagttacttc
     5701 gttttcatcg atcaaaagaa taggattcgc atcaccacgt gctttatcag aaagcatcaa
     5761 gacacgactt tcttgttggg catctgcacc ttttgcccct ttcaagatgt ggccgatacc
     5821 attaaaggtc aatgttcctt tttctcggat cactccgtgt tgcaaaatat gcccgatcgt
     5881 atgaggggct ttattggtta ctcgtgtatc gattccttgg atttgtctgc ccgagctgat
     5941 tgccacgatt ttgacttctg cgtgtgcacc ttctcctgct aaatctgagt caaagtcagc
     6001 gatcacatga ccgtcattca tgacaccaat tgcccagtcg acagaagcat ctcgtaaaat
     6061 gtgcccacgg cgattcatat aagaagtaat attttctcct aattgatcta cggctgaata
     6121 tttgattttt gaaccagctt tagcgatgac ttccacgatg atattacctg atgattttgc
     6181 tacttgttct ttggttgtct ggaaacgttc cagataagaa aattcactat gttcatctgc
     6241 cacgatcaac acatgcttga agaagtgctc atcggatgcg ccatcttgaa tgaataagga
     6301 ctcgagtggt tcatcgatca cgacattttt aggcacatac aggaaaatac cgctgttcat
     6361 aaaagctaca tggagtgcag tcaattggtc ttcgttcatg tttactgctt ttttcatata
     6421 atattcttgg actagttctg gatattcgat cattgcagtg aacaagtcgg taaaaatgac
     6481 tcctttttct gctaattcca caggcagttg ttcaaaaatc gtccatgaac cttgttggac
     6541 aagcacagga ttgtctttca ttgcatcaaa tgccggaatc gtgcctgttt cactgatggt
     6601 ttgtgtttct ttcacatcaa ataacgacca gcgatggaat ttcacccgat cgatatgcgg
     6661 caatggcagt tcatctgctt tcgctagtgc gtcttgacgg aaggttctca tccaatcagg
     6721 ttcgccttta cttaaagaaa aatcatttac cgcgtcaaga taatcgagcc agtttttttc
     6781 tttcattctt gctccccctt acgcttcttc ttctttatag tcgattccta attctttact
     6841 gataccagcg tagccttctg cttccagacg tttagctagg tcagcattcc ctgtcatgac
     6901 tactcggcct tccatcatga tgtgaacgac atcaggtgtg atatagttca ataatcgttg
     6961 atagtgggtg atgatcaatg caccgaaatt gtctccgcgc atttcattta ctcctttagc
     7021 aacgactttc aaagcatcga tatccagacc tgaatcgatt tcgtctaaaa ttgcaaatgt
     7081 aggttctaac atcaacaatt gcaggatctc attccgtttc ttttctccgc cagaaaaacc
     7141 ttcgttcaga taacgttcag ccatttcttc tggcatattt agtaaagcca ttttttcatc
     7201 taactttttc aaaaatgcca taacagaaat tttgtcgttt tcatcacgtt tcgcattgat
     7261 cgctgcacgc atgaattccg cattcgtgat acctggtatc tcacttggat attgcatagc
     7321 taaaaataag ccaagtcgcg cacgttcatc tacttccaag tctaaaacat ttttcccgtc
     7381 aaacaaaatt tcgccttctg ttacttcata gtttggattg cccatgatag cggcagataa
     7441 ggtagatttt cctgtgccgt taggtcccat gatggcatgg atttctccgg ttttcattgt
     7501 taggtttacg cctttaagga tttctttttc ctcgatcgac acatgtagat tttttatttc
     7561 taagacagac atgcattata cccccaaatt ctctttcgtt ctcactcatt ttagactaat
     7621 tgagaatgaa gcgcaatgac cttccttact aaaatcaaat atcttttatt tattattaaa
     7681 caattttgat ttctaaatta gaataggtat aaaaaagatg agaaataagc cattacagac
     7741 ttatttctca tcttttttgt tccatacctt attttgcatc agcctttact ggtttaacag
     7801 agccgcccca tttgtctgtg atccattctt ggacttcttt gcggtgaagc acttcaatca
     7861 gttttttgat tttgtcactg tcttcatcac ctttacgagt cgcaataata ttcacgtaag
     7921 gagagttgtc cttttcaagc aatacggcat cttctaatgg attcaaccct gcgccgtaag
     7981 cgaagtttgc gttgattgca actaggtcac cttcatcatt ttggtacgta gaagctaaaa
     8041 gtgatgggtc gatcgtatgg ttgaacttca agttcttagg gttttcttca atatcatcga
     8101 atgttgctgt ttccagatct actccatctt tgactttgac taagccagca tcttgtagaa
     8161 ttgtgatgat gcgtccccag tctgattcag aatttgaagt aatgattgtt gcaccatctt
     8221 ttaattcgga aacatctttg acttttttag agtacaagcc cattggttcg atgtggacag
     8281 caccggcatt gacaaagtca tatccttttt ctttgatttc tttgttcaaa taaggaatat
     8341 gctggaagta attggcatca atgtcgcctt cttccaaaga ttggttcggt aatacatagt
     8401 catcgaattt gacgatttca agatcgattc cttcatcttt caataatggt ttcacatgtt
     8461 ccaaaatctc tgcgtgcggt gtcggtgaag cgccgacttt caatgtcgtg tcgtctgctt
     8521 tatttgctga atctttgctg tcgctgttgt taccgcatgc tgctaatcct acagtcagca
     8581 aaagcgctgc tgcaaatcca aaaattttct ttttcatatc ctacatcccc ctatatccta
     8641 ttatcttttg tctgttttct tagttaagaa atcaccgatt ccttgaacga taaatacgat
     8701 tagtaaaata attaaagtcg caacgaatgt cactgttaga ttaccacgct ggtagccttc
     8761 ctgccaagca agacctccaa gtccacctgc gccgatcgcg ccggccatcg cagtaaatcc
     8821 gatcatcgag atcgttgtaa ctgttaatcc agaaatcaat gcgggaatac tttcaggtat
     8881 caagaccttc cagatgattt cccagtaact tgctcccatt gcatctgctg cttccagtac
     8941 accagggctg acttcacgaa aagcaatctc tactagacgg gcataaaatg gtgctgcgga
     9001 taaaacaaga gctggaatgg ctgcttgcgc acctagcata gtgcctacga ttgctttagt
     9061 aaatggaatg atcaaaacca tcaggatcat aaatggcgtt gaccggaaaa tattactgat
     9121 gatcgatacg attccataaa tgattcgagc atacggtttg tttttgcgtc caatagagta
     9181 aaggatcaat cccaaaacta atccgatgat cgtcactaag accattgaga ttaatgtcat
     9241 atatagtgta tcaaggatag cctgattcat cgtttccggg ttgatttgtt taaaatctag
     9301 atatgtttct gaaaagcttt tatccacgat ggatcacctc aattcctact ccttgttctt
     9361 tgatgaacac ttctgcttga tctaattctt tggtttcacc agtcatcaag acagtcaatg
     9421 aaccaaagga accttctttc acttgtttga tctttccata cacaacgttg acatcgatgt
     9481 tatagcgtcg aatcgcttgg gaaatgactg gctcgttggc atttctttcg ctaaaggtca
     9541 aagttgccaa acggccgctt ggattttctt tgatgagttc agctaatagt tctgtcgaat
     9601 cagcttctgg ttcgatgtct tgttgtacaa agcgtttggt tacttctttt ttcggttgtc
     9661 tgaagacagt caatacgtct ccttcttcta cgactttccc caactccatc acagcgactt
     9721 tgttgcagat tttgcggatc acattcattt catgtgtgat caagacgatg gtcaaattca
     9781 atttcttatt gatcgctaac aataagtcta atacttcttc tgttgtttgc gggtccaatg
     9841 cgctagtagc ctcatcacaa agcaggatct caggatcatt tgccaatgct cgtgcgatac
     9901 cgacgcgttg tttctgtccg ccggaaagtt gtgaaggata tgcttgtccg cgtccttcta
     9961 acccgactaa acgcaacagt tcttctgccc gttctttacg tttgctcttt ggtacgccag
    10021 ctaattccag cggcagctgg atattttcaa gtacagttct tgaccataac aggttgaaat
    10081 gctggaagat cataccgatt ttctttcgga atgtacgtaa ttctttgttt tttaattttg
    10141 taatatcttg atcgtttacg atcacttcgc cgctcgtggg aagctcaagt ccattcagga
    10201 gacggactaa tgtacttttt cctgcgccag aatagccgac gattccataa atatcccctt
    10261 tttcaacgtt tagtgaaacg tcattgacgg cttggatgtt tccgtttttc ccattgaatg
    10321 tctttttgac attcgttagt tggattaatg acatgccatt cacatctttc tcttataatt
    10381 tttcaaacaa aaaagccttc gccctcttgc cttaagcaaa aggacgaaag cttgaacttc
    10441 cgtgttacca ccttgattta ccgttacttc gcaataacag cctcttccag tacttggact
    10501 tagcttcttt ccgtatactg tcgcgctgta acgggcactc ccgtagtaag tttgcttacg
    10561 ctcgcttact ctgctctaag accatcttcc atctcatttt cgttacccat tttcagcaaa
    10621 cagggctctc ttcaaacgtc cgtgacatgt actcttcttt tcaaagcttt ctcgtttcat
    10681 ataggattgc ttatgattat agcaactgga agaatcagtg tcaacttttt tcaagtgatt
    10741 ttctgatttt ataattcgtc aaattctttt ggatcaacat ctttgaaact taagatccac
    10801 gcattcattt catctgaatc attcaagata ttgatatctt caccgatttt atcattaaca
    10861 gaagaaactg tacccgttag cgggctggca aattcattga ccgctttttc cgcttcaact
    10921 tcgatcagag gttcatcttt ttttagcgat tgtcctgctt ttggcagatt ggcaaacgtg
    10981 atgtctccaa gttcttcttg cgcttcattt gtcaaaccaa cacagtattc ttttccatta
    11041 aataagatcc aaaggttgtc ctttttcttc aaatgcttgc ctgccatttt atatcagttc
    11101 tccttcataa attttttcat tgaatccaat tgcaacaagc tggtcctctc gtaagatcag
    11161 tggtcgcttg atcagcatac catctgtcga taagacttgg ctcgcttttg aagccgtaaa
    11221 ctcgcctact tgatctttca gtccaagttc ccgatatttc atcccgcttg tgttgaacag
    11281 gcgacggatt ggtacttgac tcgtttctag ccaagtctca atcgttgagg ccttcggtac
    11341 ttctttgatc atatcaacgg tttgataact aacgccatgc tggtctaacc acgctttggc
    11401 ttttttgcat gttgaacatt tcgggtacca gtaaaaggtg tacaattttc ttacctcctt
    11461 gaagatcttg caggtgcttc attttggtat ctcatcgata atatcaaccc gataccgatc
    11521 atgttcccta aaatcgagga tcctccctga ctaatgaaag gcaatgggat ccctgttaaa
    11581 ggaagtaatc cgatatttgc tccaatattc tcaaagacat ggaacagcag catcatgatc
    11641 aaaccgcttg cgatataggc gtaaaattca ttattcgtat cgaaacacac ccgaatcata
    11701 cgatagatta aaataaaata caagaaaatg acgaatgcac caccgataaa gccgaagttt
    11761 tcaccgataa cggtaaaaat catatcggac tcacgaacag gcacatagat attgcttacg
    11821 ttgaatcctt taccaaacaa gccaccggta ccaattgcca aaagtccttg ggccggctga
    11881 taactcattc ctgacgtatc atggaaaggg tccagccatg aatcaatacg tgcaaactga
    11941 taagatttga atccaacttt ataaagcaag tctcttccgc cttcagtcgt aaccaagaag
    12001 atcgttcctg ctccaacgac tactgccaag attactacag gtgcgatgat gcgccaagag
    12061 attccagaca tcaggaaaat cccgccaaag atcgcaagaa agacaagcat cgttccaaag
    12121 tcatcttggg ccatgatcaa tgctaaaacc ggtattgtca cgatcaagag cttcccaatc
    12181 agccaaaagt ccgatttcat cgtccgttct tttacttgcg tattatgttt agttacgatc
    12241 agtgccatca tcaagatgta cgcaatcttc atcaactctg ctggctggaa agtaaacgca
    12301 ccgaatcgaa accagttttt agaccctgtt gaagcagcta aattctgatc atagaatttg
    12361 agcaagagtc ccattaccac taaccccaaa ccataaaggt aaggagtcag tttccagatc
    12421 catttggaat tcaaatgcat gatgacaacg attgctgccg ctccaactaa ataccagaca
    12481 acttgcatcc ctacgccttt caagactgct ggattgttcg gatcatggct aagtgctaca
    12541 tataatgaga gcagaccaat caaacataac agaaagactg gtaaaatcac gccataatca
    12601 atacgattat cgttcgaagc ttttaatttt ttttccatgt ttcatccctt ttcttaaaaa
    12661 ccatactgct gattattata gcggtccagt tagataatgg aaagtctttc catagacatt
    12721 tgggaaaaat taactttccg tttgtgcagt tgcttgagca aatgcagtac aaaagcctac
    12781 tgcttatctt tagtgtatca tagaactttt tttgatacat gcaattatct accagctgag
    12841 attctcctcg ctgtgagaag tttctgtgct ttcattgtat cgaaggatct cttcggcaat
    12901 ctctagcagc tgatcagaaa ccagattggt tcgttggatg aaataaaaat atcgatggaa
    12961 attcaacgga gtcattggca cattttctgg aacagagcgc ttagacaaaa tcgagcgacc
    13021 gattccttcc ttcagcaacg caacaattac atcgttactt ttcacgatca tcttcttatc
    13081 ttggatattc atctcttcaa aataacgctg cgtgtaatga aaaacaccag agtttgcttc
    13141 tcttacaagc cacaatttgc tttttgggtc cccagcgatg actagctggt cttccatcaa
    13201 agagtatctt tgtacgccgg aagtctctaa tggcttttcg ataaaaccaa aatcggattc
    13261 atgtttcgct acttgttcta atgattcatg agaattcgtg atttcgatct caaaatgcac
    13321 tttaggaaac cttttgatca gatgtttcat caactgaggc aaaagataga cagcaaaggt
    13381 gtgggaagca acgatccgac atacttcttc ttcattttgt tcattgagca atttttgctg
    13441 agtttcttcc cattcttcta acaaaaccag tgtccgttca tataataagt cggcttgctt
    13501 agttggaagc atctcttttc ttccgttacg ttgaaaaaga tcgatattca attcccgctc
    13561 caactgtttg atttgattcg agactgctgg ttgagataaa aacagtactt ctgctgctct
    13621 ggaaaaattt cttgtttcat atactgctcg aaaagtcgtt aataacttaa acatggcacc
    13681 acttccataa ctttttatga taattactat aaaaactatt tgatttaaat atacaaaaaa
    13741 ccatctataa tagaaatgta caacaaaaca gttgctgatc caactagtaa cttagatgaa
    13801 gacaatcagc tgtctgcttg ctcgtaatca tacattccta ttcattttac aatgtattcg
    13861 ttcatcttgg tactaaaatc tattaaataa aaaggagaat attatatatg aagaactttt
    13921 tgaaaattat tccgatcccg atctgcgggt tgatccttgg gttagcttcc cttggaaatc
    13981 tgtttaaaga ctatcaccat gttgctttag gcaatctaac tggcggtatc tctatgattc
    14041 ttatgatatt catttttgtt aaattgttta tcttattcga acacacgaaa caaacgttgc
    14101 atgatccaat catcgcctcc gtttcaccaa cttttacgat gtcactcatg gttatttgta
    14161 cttattttgt ttcatatgaa agtattgcac caattgtcaa attcatttgg ctgtgcgctg
    14221 ttatcttcca agtgatcctt gtcttttatt tcaattatca ccatgttatc aaagctgatc
    14281 tttcaattga agcaatttat ccaagctggt ttatcattta cgttggattt ggggtcatca
    14341 ctgtaactgc cgggaacttc ttcccactta ttggaaaaat tttcttttgg atttcattga
    14401 tctgctatgc gttcttattg ccgatcatca tcaaacgtgt ctttttcgta agaaatatgg
    14461 ctcatccgac acgtccgctg attacgatcg ttgcagcacc tggttctctt tgcctaacag
    14521 gttatcttaa aaactttgct gaacctaatt tttatcttgt cgtagcattg ttcgctttat
    14581 ctcaagtatt gtatttcgtt gtgctgtcta tgcttccacg tttgttcaag cttcgttttt
    14641 atccaagcta tgcagccttt acattcccgc ttgttatctc tgcaacagct atatttacta
    14701 ctgttcatta cttcaacagt ttaggtatct atagtagcgt attggatttc ttaaaagttg
    14761 cggaatgtct gtttgcaagt gtagttgtct tctacgttct tgctcattac gtacgtttct
    14821 taattaaaga acatagcaaa catggaaaat ttgtttctaa aaaaatcgct taataatcga
    14881 ttcaataggt tgtgaaaaag ctgttctgca tcaagtaata agaacggcca aacaaaaaca
    14941 gctgttcatg tttttgtact ggttgggctt attaccgcag atgcaagctt ttgaacaccg
    15001 tttaccaaga ggtcgtaaaa gaagtggtca gcttcaagaa ataagaagga atttacgaaa
    15061 attgcttctc aaatttttgt gaaatttcgg cttatttccg tagaagctac ttctggaaca
    15121 ccgtttattc gaaacaagag gtcgtacaag acttttgtca cgacctcttg ttcttttgtc
    15181 aaaatactgg tttagtgcta ctatgttcga gtatgctttt agtatttatt gacgaaagga
    15241 accgatcaaa tgaaatcatt gtcacatcca ataaaatctg taaaggattc agcggtccgc
    15301 gaaatcttac ccggtttact gctttctttt gccatcgctg ccttcagcag gcttcttgct
    15361 atttatctgc cacagttagg tggagcgact attgctattt tattgggtat tttattagga
    15421 aatacttttt ttaaacagcc tgttctagca atcggcacaa aatttgctga aagcaaacta
    15481 ttagaattct ctgttttttt actaggtgca actgtcacag ctcaaacgat tgctcaaatt
    15541 ggtgtaaaag gaattgtttt tgtgttactg caaatgtcag tcactatcat cggtgcttac
    15601 ttgattggta aaaaactgca attcagcgat acttcttctt tgatgatggc tggaggaaac
    15661 gctgtttgtg gttcttctgc tattgcttca atcgcccctt ccatccatgc gaaagaggaa
    15721 gaaaaaggac agatcatcac actagtcaat ctactgggta ctgtgatgat gttgactctc
    15781 ccttttcttg gattacagtt gtttggtgga aatctcattg aaaaaagtgc acttttgggt
    15841 ggtacactcc aatctgttgg tcaagtagtc gctggggcaa gcttacttga caattctgtt
    15901 gtcgaattcg ccatgctatt taagattcta cgtattatga tgctcgttgt tgttgtctat
    15961 ctgtttgaaa aattcatgca caagaaacaa ccagctctgt ttgaaacgcc aactgatacg
    16021 cagaaaaaac gaaaattacc gcttccttgg tatgtattag ggtttgtgat cttttgtttg
    16081 gtcaacagct tgttttcttt acctgtagtt attgaccaat cggcacattt tatcagcagc
    16141 tggtttgaga tcactgcttt agcggcaatt ggtctgcgtt tagactttgc aaaattcatg
    16201 aaagaaggta cacgcttctt atcttatgga ttagctgtcg ggcttctcca aacagtgatg
    16261 gctttactat ttatttggct gatcaaagtt tagaatgaac atgaaaaaac agttgtgatt
    16321 ctcgcatgga acaatgtccg aatcacaact gtttttaatt ttgcagatat ccttctaaca
    16381 acaacaattg gcgtttgatt tcaaccccat ctattgcgtt tcccatatat cctgtcagtt
    16441 ttccattttg cccgatcact cgatgacaag gaataacgat tggcaatgga ttggttcgat
    16501 ttgcctgccc aatcgctcgc acagctttcg gactatcaac agcaacggct acttctttat
    16561 acgttcggat ttctccataa ggaatggtcg acaaagcttt ccagacattt tgctgaaaag
    16621 gcgtacctct ctttatagat aaaggaacat caaattcttt tctttttccc gcaaaatatt
    16681 cttcaaactg ttcttgtgtg cgcgttaaaa ttcgctgatt cgctgattcg ctttctgaaa
    16741 ttggctgaaa agatacagca gtcaatccgg attcatctgc atctaaccat aaaaagccga
    16801 taggtgtgtg tattttcatt ttgtttgctc ctagtcaata gactggaact tcctcctttt
    16861 tctctatcca aaactacttg ccaactaata aaaattgttc ttaaaagttt gataaaccga
    16921 ggaaacatgg taaactaaat acgttagttt acaaaaagaa tacctgttct tttacgtaaa
    16981 atcaaatttt aaaggtgtta tttaaggttt attaaatttt gaatgtaaac catatataaa
    17041 catacgattg aaaggataga aacgatgaaa gtatcaattg ttgtcccatg ttttaatgaa
    17101 gaaaaaactg ttcctctttt ttttgatgag gttgaaaaat tcaaaggtgc ccatgagttc
    17161 gaatatttgt ttattgacga cggatcaaaa gacggtacgt tagcagcaat caagaagcta
    17221 gcctcagctt atccttatgt ccgctttgtc tcattttcca gaaattttgg gaaagaagcg
    17281 gctctgtacg ctggattgca agcttctaca ggagatttag tgaccgtgat ggatgttgat
    17341 ctgcaagatc cgcccgaact gcttcctgag atgatcaacc ggatcactac ttctgatatc
    17401 gattgtgtcg gcacccggcg ttcgactcgt gaaggcgagc ctgcgatacg cagtttcttt
    17461 gcgaaaaaat tctaccagtt gatcaataaa atcagcgata cagaaatggt cgatggcgct
    17521 cgtgatttcc gcttgatgac tcgtcaaatg gtggatgccg tcctagaatt aacagaatac
    17581 aaccgatttt caaaaggatt atttagctgg gtcggattta aaacagaata tatttcttat
    17641 gaaaaccgcg aacgtgtggc tggcgaaaca tcttggtcct tctggaaatt attcaactac
    17701 tcgattgatg gtatcgtgaa cttctcggat gcaccgttaa cgattgcttc atttatcggc
    17761 gctttgtctt gtgtcggttc tggtattgca attttgttca ttattttgcg ggcattgttg
    17821 tttggtgatc ctacatcagg atggccttcc atggtctcga tcttcctgtt cattggtgga
    17881 atccaattgt tatgtcttgg aatcatcggg aaatatattg ggaaaatctt cttagaaacg
    17941 aaacagcgtc ctgtttatat cataagagaa acagaaaaag tgaagccaaa tgaattgaag
    18001 cctcaccaat aatatacgtc aaatgaagta aacatttttt taaatgaaaa aggactgtga
    18061 caaaagtctt gtcacagtcc ttttttccga ataaatggtg ttccagaagt agcttcttcg
    18121 gaaataagcc gaaatttcac aaaaatttga gaagcaattt tcgtaaattc cttcttattt
    18181 cttgaagctg accacttcta tcacaacctc tttcatatct tattacttct tcattgctgc
    18241 ttttagtgct gctgctaatg ggctttcttc tggttcttct gcttgtgcat attttttcag
    18301 caagcgtcgt tcttcatgtt tggtcatttt cttcttctgc tcttttttat caagcaattt
    18361 ttctgtcgtt ccatcgtatt tacaacggaa ataagcaccg tttttacctt cgatgatttc
    18421 cattttccgg tgacattgcg ggcatcgatg attagagact tttggatctt ttcttctgcg
    18481 gtagttgcaa tctgaattgg tgcagacata gattttgccg tcacgtgtgt ttttctcgcg
    18541 cagattggcc ccacattctg ggcatttctt ttgggtaatc gagaaatctt gatattcttg
    18601 tttgcttgat ttgatctcat tcaccaagcg ttttgtttct ttttcgattc cattcaagaa
    18661 ggttcctgct tgtttctttc ctgcagcaat agcttcaagg tctttttccc agctttctgt
    18721 caaatctggt gttactaaag agggatttac caatactaat aattgcttac ctttaggaga
    18781 tacttgcagt ccttgagggg tacgttccat cagttcagat ttgattagtt tctcgataat
    18841 ctctgcacgc gtagctgggg ttcccagact gtatttttcc atttgaccaa gcaagcttgc
    18901 ttctgacaat ggtttaggcg gtgcagatag ttcttttttg atggcgaaat cgggattgat
    18961 tctcattcct ttttcccatt tgactgtttc cgtctcagtt tcagtttcgc ctttccatcc
    19021 tgcttggacg acacgatttt gccgaaaaat gaatcgttct ttaccaaatt caaccgtaac
    19081 ttttgtttgg ctgactttat ggggttgagc aaacagtcct aaaaaacgag agacaatcat
    19141 ttgatagatt tttcgctctt cattacttaa tttttcataa cgtgctctgt tttcagttgg
    19201 caaaagtgca tggtgatcgg tcactttact gtcttggaat acttttgtct gttggacgat
    19261 ggctccgttt ttcaaatact gcttgacctc aggagcaaag tcgctgactg cttgcaatcg
    19321 ttctttcatc gtacttttca tgtcatttgt cagatatttg ctgtctgtac gcggataagt
    19381 aacgatctta tgggtctcat acaaactttg tacaagactt aatgttttct ttgcagaata
    19441 gccatagcgt tgattggctt ctctttggat ctctgttaaa tcataaggca atggcgcaga
    19501 ttccgttttt aatttttctt ggacttctgt gacagttcct ttgcttgtac tgatcaattg
    19561 aacaagtttt tgtgcttctt cttgtgtttt taaagcaaat tgattttttt gaagcatttt
    19621 ggcttgttct tttccagctt gcaacgtgat cgtgaaatac gtttgtggac ggaactgctc
    19681 gattttcttt tcttggtctc tcactaatgc tagtgtcggt gtctgcacac ggcctgctga
    19741 taaattatcc gcgtacttca cagttaaggc tctggtcaca ttcaatccta ccagccagtc
    19801 cgcttttgcc cgggcaagag cagattcata caatgcatca tattctttcg caggtcttag
    19861 ttgcttgaat ccagttttga ttgctttatc tgtttgagaa gagatccata accgcttcac
    19921 tggtttattg aaatgcacat actctaagat ccagcgagca acaagttccc cttctcttcc
    19981 ggcatctgtc gcaatgactg cttctgagac atcttttcgc tgagccagct gcttgattgc
    20041 ttttaattga tgtcctgttt taggaagtgg tttgattcct agttttttag ggatcattgg
    20101 caacgtgtcc atttgccagc tctgccattc cttattcaga tcttccggca ttttcaatcc
    20161 taataaatga ccaagggccc aagtaacgat caccttgggt ccttcataat aatttttgtg
    20221 cttttgatta gcaccaagca ccttgcttag gtctttcgca acgcttggtt tttccgctag
    20281 aattagttgt ttcataaaat tcctttctgc tttctactgt gatgggctga tgatttttca
    20341 acaacgcaag tcccttgtat tgctgtaaat catcgtcaca ctcttcacac cagcgctcat
    20401 ctccgtcatt ccaaaaggcg ctgagaaagt tactttttgc attgatatat tcataatttt
    20461 gatggatttc gttccattgt ttttcgtacg cttgtcgtgc ttcttcgaaa gactcgaatg
    20521 tttcttcttc ttcaatatct tcttcccagt cttcaaaaaa ccaccaaggc tcattgtccc
    20581 cgaacatggt aattacttga tacatactcg tgctccttct ttcagctttt ctagactcat
    20641 cttagtcact tttcaagaaa gttgcaagaa ttttctctta taaaagggtc atttaatgaa
    20701 catcttaaaa ttgttacaaa tgaatctgat tgtttaaggc aaagtagcga taaagttatt
    20761 gatcatccaa aaatagctgt cttctggatc gattgttggt tcttttgtaa agtatcctaa
    20821 aaaacgtaag gaaagataac cgtggatcat actacgaagt tccctgcttc gatgaacttt
    20881 ttcttctttc gttaattgaa aagcctcaaa tatctgcaaa atgatctgat tcgtttcatg
    20941 gattccatct aataaaacag cttcattggt atgcggtaca ctgatcagta actcatacac
    21001 tgcttgattt gaaaaagcaa aggatcgata agtttctgca tagatctgca gtgcttcctg
    21061 accacttttt cccacaagag cccgtcgcag ctggtcatta agttcctgca gaagtttcgc
    21121 tgttagcgct gttttgacat cacgaatatt tttgaaatgg ttatacagcg agggagcctt
    21181 gatatccaag cgtttggcta aatgctgaaa ggttatttgc tgaacatcca tctcttctgc
    21241 tagttctcga aagcagtcga tgattttctc ttgagacaga tttctttttt tcatttccat
    21301 gtttcctctc ataaaataaa tccttcactc tttcagttta ccacgaaaaa gaaagagaaa
    21361 aaagagactt tcattgataa actacatatt gtagtttata ataaagagct gtagatgaaa
    21421 attttcagaa agaaggagtc taattggctg caagaataaa ggaaaaatta tttaggaaaa
    21481 gagaaacttg ggaacaaaac ttgtttgtct tatggtttgg aacatttatg gctggtatcg
    21541 gatttagttt agtcatgcct tttatgtcac tttacataga tacgttaggt aattatagta
    21601 cgtcacaatt gaacttttgg agcggattga ctttttcatc tactttcttg gtgactacgc
    21661 ttatctctcc ttggtgggga aaattagccg accaaaaagg aagaaaattg atgctgttgc
    21721 gtgcttcatt aggaatggca atcgtcattt ctttgatggg ttgcgtgact agtgtgtatc
    21781 aattagtcgc attgcgtctg cttcaaggga ttttttctgg ttatatcagt aatgccactg
    21841 cccttgtcgc aactgggacg ccaaaagaaa aaagtggtca agttctttga accttagcaa
    21901 ctggttctgt tacaggaaca ttacttggac cgcttcttgg cgggatctct gcttcagcgt
    21961 ttggctatcg ccctaccttt ttcattacag ggatcatctt atttttcgtc ttcttgttga
    22021 gtctgttttt cgtccatgaa aaatttgtcc cagtgaaaaa agaaaacatg gtttctgcca
    22081 aacagatttt caaagacttg aaatatccac acgtcgtcat cggtatgttc gtcacaacga
    22141 tgatcatcca agcatccaac aattccatta gtccaatcat cagtctgtac attcgccaat
    22201 tgctgcatgg acatgggaat gttacgttga tcagcggaat cattgcttcg atacctggga
    22261 ttgccacttt gatagccgct ccaagatttg gtcgcttagg tgacaagatt gggagtgaaa
    22321 gaatacttgc gattggtttg ggttttgcga ttctggttta tatcccaatg gcattcgtca
    22381 cgaatgtttg gcaattagct gccttacgtt ttttgattgg tatctctgat gcttgtctgc
    22441 tccctgctgt ccaagcattg atcacaaaat attcgcctca tcaagctgct ggacggatct
    22501 tcagttataa ccaatctttc caagcaactg gtaacgtagt agggcctatg atcggctcca
    22561 gtgtttccag tgcatttggt tatcgcggcg tctttctttc gacttctctt cttgttttgg
    22621 tcaacttctt gcttgtacga cacaatacac aagagatcca tcagcaagaa actgcagaag
    22681 aaaaagcttc aggagtctcc atagcttcag ggcactctcc ttctcataga caataagcgt
    22741 aaatgaaaaa cactgcttga acagttgtca cagactgtcc ttgcagtgtt tttgtttagg
    22801 cctgtttttt caagaactca gataagagga ataatccctt ttccaaggtt tcttttttac
    22861 aacagtaacc tagtcgggca tgcttcggta aatcaaaggc acttcctggt actaatagta
    22921 ctcctgtttc ttctaataaa ttgatacaaa atgtctggtc atcttcttcg atggctaatt
    22981 taatgaaaga agtagagacg taattgggag cgacaagttc aactttcggt tcattggcta
    23041 cccattgttt taaaatcaca aggttctctg taatgatctt tttgtttcgc gccaatattt
    23101 tttctttatt cttcaatgca tgtacagcaa gatcatctga caggactccg ccgcaaatca
    23161 tcgtgtagtc tcgatacttt cgaaaaactt ctgccaactc aggtccagta gctgtccagc
    23221 caatacgaat acctggaatg gagtaggttt tggataggga attggttgct ataccttttt
    23281 catagacatc tacgatcgac aagaattcac ctttatccgt taaaggcgca tatacttcat
    23341 ctatcaatac atatgcatct actgtacgag caatttctgc gattttttct aaagttttcc
    23401 gatctagcaa tgtgcctgta ggattgtttg cactattcaa acagatgatt tttgtttcag
    23461 gtttgactaa ggcttctagc tgttctaaat caaactgcca atcttcttct tccttcaaat
    23521 gaacaaagtc aacagcggca cctaaagatt tggggatgtc atataattgc tgataagtag
    23581 gaagcatcga aacaacatgg tctcctgctt ccactaacgc gtatagagct aaaagattag
    23641 caccagtcgc tccattcgtt tgtaagatgt tttccggatc gacggtttga taaagagaag
    23701 cgacttcttg tttgaaaaca tctgatcctt cgatccagcc atagtccaat ggttcgtttt
    23761 tgcgtttttc gaaaaattta cttacgctag tcccatctaa gccaacgagt tcgtctaatg
    23821 tcaatgcttc gatcgagctt tgtgcaatat catataccgc tttcttttcc catttattta
    23881 gccattcttc tacaccgaaa tttgcgattt tcatgtttct ttccccctta tatcttgatc
    23941 cagcctacag caagcaaccc gattgaaagc agtgcggcca cacaaatcag cccaatcatt
    24001 actttttctt ttcccgtaat ttgatgtttg gtttcacgac aagcgatcca gtagaagcaa
    24061 aaaccaggaa gataggcaat actacataaa aggacataag aaaatcctgc taaaatgatg
    24121 cccatcaatt caaaaactac agcaatccca ccgatcacta cttgtttttt gattccttct
    24181 tttaaagaaa actggacttg atagatcccg acaagtagat aacaaatcaa aattgccgct
    24241 gtacataaag aataggcaaa ttgataggca taatcagtaa ctaagaaagt caataagaat
    24301 agattagtca agattgcagt aacaactaac gaataagttg gggcattttt tttattcgtt
    24361 tttccccaac ctttcggcaa cagaccgtct cgagccatca acatcgttgt ttctgctggg
    24421 agcatcgtcc aagacaacca agaaccaatg atcgaaataa tcaagccgat attgatcagc
    24481 gctgctcccc aatttcccac gattcctttt aaaatatttg ccatagcagg ttgtgaaata
    24541 gttgctaact cttcttgaga taagacgccg tatggcaaga tcgaagcaag gatatagata
    24601 aacaataaac aaagcagacc aatgatcgat gcttgctggg cttctgaacg tttcttcgcg
    24661 cggttggcta aaacacttgc gccttcgatc cctacaaaga cccacatcat aaccatcaaa
    24721 caacctttaa tctgcaacca gatcgttcct tgctgccctg ttccattcac tagattatca
    24781 gatacgttac cccaaaaatc agcagtgaat atattcactt taaatgcgat aaatacaaat
    24841 attaaaaata ggaataatgg cactaattta cagatcgtca cgattgtatt gatgacgctc
    24901 gctccttcaa ctccattgtt tactaataaa gtcagacccc aaataaaaat acttgcaaat
    24961 aaaatagaag gaacattttg tccacctttg aatatcggga aaaattctcc catggcgctc
    25021 atcagcatcg ttgcaaaagc aacatttccc agccacgcag acaaccagta accccaacca
    25081 ctgatgaagc cacctaattt accaaatgaa gcttccgcgt aaccgaaaat accaccatct
    25141 agatctggac gcttttctcc taaatgattc agcgataata ccaaagctaa aataccaatc
    25201 ccaacgatta tccatgaaag gatcgctggc cctggagctg cagaactagc cagatcactt
    25261 gtgatcccaa acacaccgct tccgattgac gaactgacaa ccagagcaac cagtccccat
    25321 ttgctaatac ccgtcgattt cttttccatt tccatcaccc tcacttataa aattgaacaa
    25381 atcacttgca aaagattccc ttctattttg caactgctct tgcttaacaa aaagcaactt
    25441 tattcatatt attggatatt atgaactttt tacacaagta tttcaagtat aaaatgaata
    25501 aaaattaatt ttattgcaaa aaaacagcta tgctatccaa aagaaaaggt gtttcttttg
    25561 ttagccatag ctgttttgat tcatttaata tcgcttaaac gtattgtaaa acttttgttt
    25621 cttgatatgc gtggtcgatc aaaccaccac ccagacattc cattccatca taaaatacaa
    25681 ctgcttgtcc aggagtgatt gcacgtacag gttcgtcgaa tacgacttct gcacgattat
    25741 catccaataa gcgaactgtc acaggaacgt cttgctgacg ataacggaat ttcgctgtac
    25801 acttgaattc ttttggcatt ggttcattcg tcgtaaagtg gatttcactt gcatccaagc
    25861 ttgtggcata caatgcagga tgatggaacc cttgccccac atataatgtg tttgtcgcta
    25921 gatcttttcc tacaacaaac cagggttctt gcgaatctcc tccgccaccg atccctagtc
    25981 cttgacgttg accaatcgta taatacatca agccagcatg ttgtcctttg acttcaccat
    26041 caagagtgac catatttcct ttttttgctg gcagatagtt gctcaaaaat tgtttgaagt
    26101 tcttttcacc aataaagcag attcccgttg aatctttttt cttagcagtc gcaaggcctg
    26161 cgcgttcagc aattgcccgt acttctgatt tttccatgcc gcctagaggg aacatcgttt
    26221 ttgaaagctg ttcttgtgat aattggctaa ggaagtaagt ttgatcttta ttattgtcta
    26281 ctccacgaag catgtggacc acgccgtttt catcgcgagt gacttgcgca taatgtccag
    26341 tagctacata atcggcgcca agatccattg cataatccaa gaatgctttg aatttgattt
    26401 ctttgttgca catcacgtct gggttaggtg tacgtcctgc gcggtattcg gctaggaaat
    26461 attcaaatac acgatcccaa tattcttttt caaaattcac agagtaataa ggaatcccga
    26521 tttgagcagc tactttcgct acatccttat aatcttccgt ggccgtgcat acaccgtttt
    26581 cgtccgtgtc atcccaattt ttcatgaata ttccgatcac gtcgtatcct tgttccttta
    26641 acaaaagtgc tgttacagat gagtcgacac cgccgctcat ccctacgaca acgcgtgttt
    26701 tgctgttgtc tgtcatgata tcaccatcat ttcaattaga ttctgaaaca tctacgagtt
    26761 gaaggtcgca acttttcagt attttacatt atacgtcata tttctgaaaa tttcatccct
    26821 taattatcaa gtcgtaaaaa tactgttcta ctggacctat tcagtacaca aacatgatag
    26881 tcaaccaaaa aatcactcat cttttgagca ttcgatataa aaaattggca tactcataaa
    26941 aagggccagc ctttcggcaa taaggaataa ttttataaat tgtgaaaaac tatttttcaa
    27001 aattgcttct tatcgcttaa agctgcacgt ctcatttaca accttttctt tttagatgtt
    27061 atgagttgct cagataagtg attttgttta ctctaagaaa aaagggaggc aaaagataca
    27121 tgaattactt tatcagtgat atgcactttt tccatgaacg cttattagga aaaaacgact
    27181 ttgctccgcg gctctttgca aatgtggatg aaatgaacca acagttgatc actagctgga
    27241 atgcagtaat aaaagaaacc gaccatgttt atcatctagg cgaccttgct atgcatccgc
    27301 aatatgaaaa agcaaatgca gaaattttgg aactggtcac tcaactgcaa ggaacaatcc
    27361 acttgatcaa agggaaccat gacagtcgcg cttttttccg ttatttagaa aaaaatgatc
    27421 ctaggcttac tgacggaagt cccaaatttt atttttatga tgtaggtgcc atcgttaaat
    27481 tcgaccatca acaatattac ttgactcatt atccgatgtt gctcgggcct aacgacacta
    27541 tccgcaatct tcatggacat atccatcatt acagcgtacc tatcgagaac gatgtcaatg
    27601 taggcgtaga cgcaccggaa agagaactct taaaggaaaa actaccattt ggcactccgt
    27661 tatctgagca acaaatcaaa gaaatctatg aagcaaagag gaagtacgat aggtcgtgaa
    27721 aaaactgccc tatatcaagt attaaacaaa taaagataat tactcatatt tttcatttga
    27781 gtaggcttat tgccacagga acattaggat cagaaatgga gttgtaacaa gacttctgtc
    27841 acaactccat tccatactat tcgtcttttt gctcatggtg ttcttttacc agttttttct
    27901 gtaattcttt atcataattt cgggcagctg acgttaaaaa taaaacgatt ccgcataata
    27961 aaatcccgat tccggaaaac aagaacattt tttctacccc taaacgatca gctaatggtc
    28021 ctgcaaataa taatccaatt ggacctgcca ggttcatcaa agagttgaag ttccctaaga
    28081 cacgacctaa aacattcgat tcataactct gctggatcat tgccatcagc agtgtattga
    28141 aatatggcgt tgcacaacct gctcctgcat tcaagataag aaagtacaag aacccttgac
    28201 tatcgtttgg aaccaatccg cttgcaccga tcgtcaggcc cataatgatg taggctataa
    28261 taataggttt cattcggtct ttccatgttc ctataaaact gatcagtgca ccgcctaaga
    28321 gcattccgac tgcgtagact acttccactg ctcccgcctg tccaacggaa ccaccaaagt
    28381 aatctagcgt catcaatgga tacagactga ttgctggcat gaacaacagc atcacaaatg
    28441 caccattgat cgttatgtac cataaccctt tattatccat caattgctgc agcccaaatt
    28501 ttgcatcttt aaaaatagta agcggaactt ccaatatttc aggagaaact tttgggatct
    28561 tcacaaaaat caataagccg acaccaaaaa ctgcccccaa tacatctaat aaaataaggt
    28621 aattgacagg aacgactgaa aacaaagccg cacctagagc tggcgcaatg atgaaattcg
    28681 ctgattggac cattcctaac tgtccattcg tccttgttat gtgagaagat ggaacgattg
    28741 tcggcataat cgactggatc gttggcattt ggaatgtttg tgcgaccgaa cgcataaaca
    28801 aagacacaaa aactagccaa atcgggaagg attctgaaat cgttccgact actgctaaaa
    28861 taagcgcgaa aatcgctaca ataatatccg tgacaatcaa aagagctttt ttatcccagc
    28921 gatccactag cggtcctaca aatgggctta gtaaaaccat gggaatcatt cctagtaaag
    28981 tagcaaaact caaaattgtc gccgaaccgg tttctcttgt caaataccag atgatcgcat
    29041 attggacgac catactagtg attcctgaca aaaactgtcc cgataaaaag aacaaataat
    29101 ttctcttcca attcgttaaa acgaccgact gttcattttc cataaacatc cctcttttct
    29161 ttttcatttt gtatagcgtt tgcacaacaa tcattatacg ggattctttt ttcaaaaaat
    29221 acctttttcc ctaaataaca atcgtttcaa tttaaatttc tttacttaga aacaataaat
    29281 cagcaaaata ttaaaaataa caacatgtgt taaatttaaa aataaaaaag acaactaatt
    29341 tgcgtcgtcc ttacaaagtt agtcatctaa caataggccg tttcaaaact agttgtcttt
    29401 ttatatccac agatcattcg actttttcga ataacccacg gctaatcatc ccatccatca
    29461 gaaaataaaa tttatcttgg ctcattttct gttttggatc tttgaaaata ttgactgctt
    29521 tcaatccatt tgctgtagtg atcgacattt tcaatgtttg aatatctttt gatacagtga
    29581 tttttaattt gaatccttct ttgctttgcg gcgtggcatc taatggtcgg atcaattgat
    29641 aattgcctcc gtttgtttct gtaaatccat tatcgcgcaa tgtatatctt tttgcatcag
    29701 gatgcaaacg atagctaatt ggtgcgccca gtaccgttgc tgttgtttca aatgccatga
    29761 ttttcacctc gataaaatta gtttctcttt attataaaag tttatcctga tttttactag
    29821 gtttttcagt taagttccct aaaaaatgaa ggcgttctct cagacatctg ttcatataag
    29881 aatgacttca ctagttattt tttgacagca cgaactaatt gatcaaggaa atactggatg
    29941 tcgtcttcgg tatttcccaa accaaagctg atacggatgg attcttttag tatcggtgta
    30001 tcttctccat acattgcttc taatacgtgt gaaggctcga tatttcctgc tgtacaagct
    30061 gaaccagtag aaatagcgac cccattaaga tcaagcttca tcagtagcaa atcatttgct
    30121 tcgccaatta agcgaagatt caacacatga gggagtttat tcgttaaatc accatttact
    30181 tgataaggga tttcgtttgc ttctaatgta tcaagaatca attgctggaa tcctttatat
    30241 ttgttgttac gtgcttcacg ttcttcaggt gacagcagtt caactgcttt tgccataccc
    30301 cagatccctg ctaaattttc tgtacctgca cgccgctttt cttcctgctc cccgcctaaa
    30361 agcaatgcag ggatatttac tccgtctcgt ttatataaga aaccgacgcc ttttggccca
    30421 ttgattttat gagcagagat acttaataaa tcgattccta attcttctgg atggatcgtt
    30481 tggtttccgt acgcttgtac cgcatctgta tggaaataag ctggatgatc cgctaaaagt
    30541 tcaccgattt ctttgattgg catcaaattt ccgatttcat tgttcccgta catcacagag
    30601 accaagatcg tatcttctcg taacgctttt ttgacctctt cgatcgacag attccctttt
    30661 tcatctacag gcagatatgt aacgtcaaac ccctttgtct ctaaatattt catggtatta
    30721 agaacagcag gatgttcgat agctgtagtg attagatgtc tgccttcttt ttgacgcgag
    30781 aacgctgttt ctaagatagc tgtattatcc ccttctgttc ccccactgtt aaagatgatc
    30841 tcgtgaggtt ttgcttgcag actgtctgca atgatttgtc ttgctgtttc caatttttca
    30901 tgcgcgtggc gaccaaatcc atgtatgctt gaaggatttc caaacgtgtc ttgcatgatt
    30961 gccgtcatcg cttcaattac ttgtggatgc atgggggtag ttgccgcatg atccagataa
    31021 atagttttca cttcattcat cccttccaaa ttattgctag gcacattcta gcataaaata
    31081 gcgaacaaac caaagaagag ctcatttttg tctagaggac gtttcatggg catagaaaaa
    31141 aggagctgtg acaaaagtct tgtcgcagct ccttgaagct gctcacttct gtcacaactt
    31201 ctttccctct tttttttgtt tattcgaatt ctttttcttc cagacggaat aacggactca
    31261 tcggtgtatt ttcatggatg cgtttgaccg cttcacccat taattctgaa catgtaacga
    31321 ttgttaagtt ttctggatga cgattttctt ctgtgaaaac agaatcagtg atacaaatat
    31381 ctttgattgg tgcattgtct aaaatacttt tcgcatgatc ggacaataat ccatgtgacg
    31441 cacaggcata tacttctttt gcgccgtttt cttttaatac atttgctgct cgtgcaagcg
    31501 ttgctcctgt gttcaagata tcatctacca tgatacatgt ctttccttga acatcaccga
    31561 tcacataacc accctcagtt gaagcatcat ctgcatgatc tacgatggct aatgtgctgt
    31621 tcaaatattc tgaaagacta cgtgcacgct gaacaccgct gttttttggc gaaacaacta
    31681 cgatgtcatc tcccgtcaga cctaattgac ggtaataatg agcaaacaac ggcatcgtaa
    31741 ataaattatc tacaggaata tcaaagaatc cttgtacttg aaccgtgtgc agatctaaag
    31801 tcagtactcg agttgcccct gcttcttcga tcaagttagc gatcaatttc gcagtgatcg
    31861 gttcatgagg tttcgccgtg cggtcttgcc tagcataccc atagtaaggc aatacgacat
    31921 tgatcgtttt cgcacttgct cgcttcattg catcgatcat gatcagtagt tccatatagt
    31981 aatcattgac aggtgcattc gttgattgaa cgatatacac atgatcccct cgaatacttt
    32041 cttcgatatt gatggaaatc tcgccatcac taaattgctt cacgacgctt ttacctaatt
    32101 ctgttccgaa cactttcgcg attttttcag ctaatggacg gttgccattc aaactaaaaa
    32161 tcttcaacgt gtcatcctga tacttattac tcatgtagtc ctccccaaaa cttctctatt
    32221 cttcgatagt ttaacatatt tttccaagat tttctgttaa tttcagcaaa ttcttaagga
    32281 agtgaaactg ttccgttact ccaactggca ggaatgactt tatgataatc gccccagttg
    32341 tcgtgtactt tgtaataacg ttctcctgtt tcagtttcaa aataagcgta cgctgtcacc
    32401 caatgattgc catatgtact gccaagtact ttcaaaatac caatcatcac aggtttgcct
    32461 tcacgtatac gttttgtagc tcgctgccat gaacctagaa gagttgctcg tgcacgctca
    32521 tgattgccat tcttctttaa aaaactagaa atccctgtac taacctgaaa aggaatcgta
    32581 ggaagtccta gtggttggat ctggctacgc aatgccttcg tcaaaaccaa cgaatcagcc
    32641 gtatttttct tgcgaatctc atttggaagc atccacccct tacgatagtc ttgataatag
    32701 gcaaggagaa ctgctgccgc gtaagtacca caaagatagc ctgagggggt agcccatttc
    32761 ttatacctca aaaaacgttc ttctggcaat cccacccagc aatttgcgag ttcctttcct
    32821 gacctttttt cttcgatcaa aacgggaata tcttcttttc tgttgatcca tctagataac
    32881 tcgattggct cttcattgat cagcttccat tttttacaag aaagaccctc ttgataagta
    32941 tattttgctg gagaatattc taccggatgt cctgattgat cgataatcac ataactttga
    33001 tcttcaaaaa ccagagctaa aaaaagcaat ttactttttc ttgactgcag ctgctgagtg
    33061 ctggctaatt ttttaatttt tttatctact ttgaaatata aaggtttatc cactacttga
    33121 ttcagttggg atcgcctcct ttttttcatt ataagtgaag gattgaaaaa aacaaatcag
    33181 tttgattgtt cgaattttca attttttatg ttctatttgt taattccttc attttgtaag
    33241 ataatgggca cacgaaacaa aaaaggagcg atcgatgaat gaacaaagaa cgattgaaac
    33301 aagatttcta tgaagcagtc aatgaagaat ggcaaaaaac agcaaaaatc cctgcagata
    33361 aaccagctac aggcggtttc caagatttag ttgacgggat cgaccaactt ttgatgggag
    33421 aaacagacga tctgcttgcc catccagaaa aagtgtcttc agaaaaaatg aaacatttcc
    33481 ttgcatatta tcaactggca aacgattatg accgaagaaa tgagttgcat gctcaaccgc
    33541 ttcaacctat aatcgaaaaa gttgaatcat tgcagtcttt cgacgaattg aataagcaat
    33601 ttccagaatg gctgttggat acattaccat tgccatttaa tctggatgta gatgcagata
    33661 tgaagaatgc gcaaacgaac gccttctttg cttatccgcc ttctttattc cttccagata
    33721 agacgtatta tgcatcagac catcccaacg gtgcacaact aataggcgtt ttctttgata
    33781 tggctgttca gttattagag cttgccggca aagaaaaaag tcaggcagaa gcaatcacgg
    33841 aacaagcagt gcaatttgat aaattgattg ctcctcatgt aaaaagtgca gaagaaaacg
    33901 cagattacag caaaatgtat aatccgcaat cttttgatac atttattaaa tacacagata
    33961 aactggactt gaaaaaactt gtcacgggtt tgattgggac aactccagat aaagtgatcg
    34021 taactgatcc agtgtacttc gatcatttga atgacatcct gacagaagct cattttccgt
    34081 tattcaaaag ctggatgatc attaaaacag tacgttctct tagtggttat ctatcagaag
    34141 aattccgcca agtcagcgga atctattctc gcgtattgtc tggaacagac gaagcaatgc
    34201 ctcagaaaaa agcagcgtat taccttgcct ctggacaatt cgatcaagta gttggcgatt
    34261 actacggaaa aaaatatttt ggcgaagctg ctaaaaaaga cgtagaacaa atggtgaaaa
    34321 aaatgatcgc cgtttataaa aaacgtctag aagaaaatga ctggcttggg gatgcaacaa
    34381 aagaaaaagc cgtcataaaa ttaaataact taggtatcca agtaggctac cccgataaga
    34441 tcccagcatt attcgaccag ttcaaaacag tacctgcaga tcagggtggt actttgcttt
    34501 caaatactct tgttttcagc aaactcacat taaaagatcg tttcagcaaa tggaacaaac
    34561 cagtggatcg ttcagaatgg gaaatgagtg ctgacacggt caatgcttat tatcatccat
    34621 ttcggaatgt gatcgtcttt ccggcagcga tccttcaagc accattttac agtctagaac
    34681 aatcaagctc tgctaattat ggtggaatcg gagctgttat cgctcatgag atttcccatg
    34741 catttgataa taacggcgct ttatttgacg aatatggcaa cttgaacaac tggtggacag
    34801 aagaagatct tacacaattt caaaacaaag cacaagcaat gatcgaagaa ttcgatggtc
    34861 tgccttttgc tgacggaaaa gtaaacggaa aattaaccgt ttcggaaaat attgctgatg
    34921 caggcggtct aagctgtgca ttggaagcag caaaaacgga atcagatctt tctatcgagg
    34981 aattctttgt caattgggca acgatttggc gtacaaaagc aaaaaaagaa taccaacaac
    35041 ttttactgca aatcgatgtc catgcccctg ctaaactccg agcaaacgtg caaccaaaaa
    35101 accttgacga attctatgaa acatttggta tcacggaaca agacgctatg tatctagcgc
    35161 cagaaaaaag agtgcgaatc tggtaagagg ttgtgccaga agtggtcagc ttcaagaaat
    35221 aagaaggaat ttgggaaaat cgcttctcaa atttttgtga catttcggct tatttttcga
    35281 agaagttact tctggaatac catgtattag aggttgtgaa aaagctgctt agtttcaagt
    35341 agtaagaaaa attttgtgaa aatggctttc cacatttttg cataaatttg acttactacc
    35401 gagaaactgg cttttgaaca ccgtttatcg agaggttgtg aaatcagcgt cctgacctga
    35461 gtattagaga aaaaaacgga aaaatagttc ctcatatttt gccgtttgtt gagctaatac
    35521 cgagggtcag ctgattgaac accgtttagt ggagagattg tgaaaaagct gtcctgcatc
    35581 aagtaataag aacagccaat caaaagcagc aaggagaacc tcatctataa aaagatagaa
    35641 ggaagtgaga catctattgg tctcatttcc ttctattttt actttcctca gtcaattgtt
    35701 ttacatcata aaaggagaaa ttccacttat ttttttcgct gtttcatgac ataaacaact
    35761 acaccgatta acaaaattcc tccagctaat gctagcaacg ggttattaaa ttctcccgtt
    35821 tttgggagtc cttgagtgcc atttttttca ctttcttttg ctgtcctatc cggatgagaa
    35881 ggttttccat ttggttttcc atttggtgat tcatttcctg gattttctct ttctggtttg
    35941 tcatttcccg ggggcacatc ggcagtttct cgcacagtga tcgctttttg ctgggtaaca
    36001 gattctgtat gagcagacca tttttcccca tcaaatattt ccgaacgata agtgacttct
    36061 agcgtatatt ctccttttga aggtgctgaa aaaatagcgg tatgattaga aaattgagca
    36121 cttgactgtg tttcaacgat ttggatcttt tctgggaaat aacgcatatc ttcaaagaca
    36181 ggcgttcctt gatttggtgt gaaagttgac acaaaaactg taaaaggctt cagttcaatg
    36241 atatttcctt ctgcattctc cgccacacca tttgcttctt gtataataat cggattattt
    36301 tgttcatttg gttttgtctg atttggttct tgtacgattg catactctgg atattccgaa
    36361 gacggtgagg tttctccgtc aaaaatagca cctacagata atggaagacc atccactctt
    36421 tccttttctg tttgacgatt ccccggttta atctgcatca gtccatgaac atggatactt
    36481 ccattttcat agcgcgtaac aggctgctga ccttctttcg aacatgtatt tagagactcg
    36541 atccaatctt ttgatatggt atgtccaaga gtattttctg attgtttctc tcgttcattc
    36601 caatagtagt tcaacgagtg gtagatttga tcttcgtttt gattcaatgg gcggatctgc
    36661 tctctcatct caagattctc tgttcggaaa gataagatac cagaagcatg gtagtctgtg
    36721 tttcctgctg aagaggtata aagagccaca ttatatgaac cgttattaaa acttgtactg
    36781 ctattgacga taatatctgt tccgctattg gaatcgattc ctttcgcaag attttcgaaa
    36841 gacaaactat tgatcaattc atgagggccc gttaaagaag aaccgcccat tttgaatcca
    36901 ttaccgttac cttctccctc aattcctggt acccagccgt ttcgataagc aactgagttt
    36961 ttgatgatta cttttccgat cgaacctgtt tcatttttag caaaaaggtc ccaaccgtca
    37021 tctgcattat gatacgcgat acaaccgtca aatacatttc cttctcctat tgtcagtttg
    37081 gccgcaaatc catcggcatc ttcaaatcct ggatcggcat tttcaaaaga tgtacagttc
    37141 ttgactaagt tatgcgcggg ccatgcttcg aaaggatcat ttgagctacc gctgatttgg
    37201 attcctgtat ttccattccg ataagcatga atctcttcga tcaaattatg atttccagaa
    37261 atctgtaatc ctttttgcat agctgcacta tttgtaatgt caaaccctcg taaaccccag
    37321 tagtgactga acagtgtcat cccatttcca gttcctttaa aatcaagtac aggacgcttg
    37381 ttttctggat ttttctctgc aatcaactga atcgggtttt ctcttgtccc gttaacgcct
    37441 tttggaatcg tcaatcctct ttcgaaggaa taagttccag gcgccatgac gattgtctgc
    37501 ccagcatatg cgtatctcaa tgcttgtgtc agagataatg gattttgtct gcttccgttt
    37561 cctgcatctg acccttctgg tgttacataa actgtcgaat atttaggttt acggtagtcc
    37621 actgtatgaa gaatctcttt tgtttcataa ctagtcatct ctacgtattc ttctggcgga
    37681 tagtttttat ctggcgtaaa actgaaagta aattcgttcg ttccttccat cagttttgtc
    37741 tgataatcaa attcccgatt cgcagtgata gccaagtttt ttgcgttctt aagcacctct
    37801 cctgttgctt tatttttaat tgtcaataat ccgtcagcat ttgctctaaa ggacatagta
    37861 tgatcttggt ttcctgaatg attactagag gtcacagtgt aaatcggatc aatcaagcga
    37921 gtaggtcttt cttgcccagg aggatctgtc gcaggatctg agtaagcaac ttcgattcct
    37981 tctaccttga tcgtcatatt ccttgctgca gcaaatcctg cataaataac cgattcatct
    38041 gaagcgtata atttttccca gtcatacatg atgtcagaag ccatttcttc tcctgtttca
    38101 ggatcgtaat aatatgcctc taaaccagta ttcgtttttt tcatctctac gtccagttta
    38161 gtaatcgagt tcgtggccgg aaacagattc ccatgaccgt ttccgaatat attataagaa
    38221 cctgtttctt tttccaagaa ccctgctgaa gtctctaaag gtgttgtttc cactgagaca
    38281 ctcccaggag ctggcgcagc ttgcggatct tcagatgata ttcctgtgat tgcccgtgtc
    38341 cccaatccaa gtcgcatcgt atatttgctg ccgctcgtgt tgaccacttc ttgtctatcc
    38401 gagtcccaga catattcgat ccgactgcct agtatggcaa atgaatttga ataaaatgcc
    38461 tgcccaaaca aatgattttt tggtactgcg tctcttacca ttaaagcaaa tccttcttgg
    38521 gcattcgtat aggtccaaga ttctatttcg atcgtcgccc gcatcctaaa gttgatgtct
    38581 ttggggattg cttgataata ataggtcatt ccatctgatc cgcttgactg gaattttccg
    38641 ccgttattcg tggaagagag ccgcacgccg tcttctaatg gttcaatggc atacctacta
    38701 gcacttgtgc tttctccgaa aacaacccct ttccactctt catttgcttc ttcagattgc
    38761 ttttttgtct tttcattttc tgattctttc atcataggat catttccttc ttccgtatcc
    38821 atatcttcac tagttcttgg tatttcctcc attgttgaca tcccttcaat gttcacgtgt
    38881 gcattttctt cgttcacaga ctgttgttcg ttagcagcaa cttcaacgac agaaattaaa
    38941 accggggtac tgagcataag gagattcatc attagcgcac tgtattttat acgttttttt
    39001 aacaagtgta ttcctcccgt aacaaattag aaagcgttta cttaaagtat tacctaattt
    39061 atttttactg tcaataaaaa acaaaattat aataagtgta ttttataaaa agaaaaaata
    39121 taacttaagt tgttgataat aaagagattt attaacggaa aaagaataag tttttttaaa
    39181 ataacgtata aaaaagagca taaaacaaag tcgtttgttt tatgctcttc ttttattatt
    39241 ttgtgctttt tattttatca aatcactttg tttttttata aaatttctgc gcctagtgtg
    39301 gactcaaaat gtctcaatgc ccattcatgt ccaacgggat cgaaacttgc cacggaatct
    39361 ttgaaaatat ggagtttgta tcctagatta tacgcatcga ctgctgtatg caacacacag
    39421 atatctgtac atacgccggt caaataaata tctgtgatct ggcgttctcg caaacggatg
    39481 tctagatctg ttccactaaa agcggaataa tgccgtttgt ctatccaata aacattttcc
    39541 tcttgctcat agtcttggta taaacttttt aaagagccgt acaattcccg tccacccgtt
    39601 cctatcacat tatgcggagg aaataagcgg ttctccggat gaaaggaatc ttttggatca
    39661 tgcgcatcaa tggcaaaaac gacaaaatcc ttttgatcaa taaacttctt tgtatgagca
    39721 gtcagctttt tttcaattac ttgtcctgct gtcccagtag tcagctttcc atcctctgca
    39781 acaaaatcat atgtgtagtc aatcgagatc aatgcgttca tcttagtcct ccttatacga
    39841 gatgtttgac aaattcgatc accatttctg ctgatcgttt gcctgcgtct tcgataaatt
    39901 cgtcaaagct ttgtgtcgcc gagtgatctg ctgtgtcgct cattgcacgt acgatcaaaa
    39961 atgggatatt gaactgacga gctgtttgtc caacagcggc tccttccatt tcgcaagcta
    40021 atgcttcagg gaaattcgtt aagatttctt tgattttatc tggcgagtcg acaaatgtat
    40081 cacctgtaac gatcaatcct tcttttgcgt tcaaattcgt tgcttttgct gctttaacca
    40141 tttcactgcg caaatatgtg cttgcttcat aatatagagg cattcctggt aattgtcctg
    40201 ggttgtagcc aaatcctgtt gcatctgcat caaaataagc tactttgtct gatataacga
    40261 tgtcacctac ttgtaagcct tcaccgattc cgccagctga acctgtattg atcaccatgt
    40321 tcacgccgta ttgttggatc aacagacttg tggtaataga tgctaagact tttcctatac
    40381 cggaacgtac gacgatcact tcgtggttac ctaatgaacc tgaaataaat aaagcgcctg
    40441 cgcgttccca tgataatggt tcgcttaggt tctctctcaa aatttttact tcttcttcca
    40501 ttgcgccgat aataccgatt ttcatctttt taattccttc tttctatata aatgcgattg
    40561 ctaaaaaaac cacacataac attaggataa caataataag agatttcatc aaaaaagagt
    40621 tccatttggt cgtcttttcc cgttcgctga tccttgtttt cgtgattggt ttattctttt
    40681 tgctttcttt acgataaaag ctggcaatct ttttttcttc ttgctgataa gctgtttctg
    40741 cttttcgctg tttttttaat gactcgcttg cttgtgcttg ttgtcgcttg cgaagttcgc
    40801 ttcgcgtaat aagcggtcct ttggccataa gccgatccct ctactttcct ttggtcaata
    40861 gttcccagta ttgaatcgca taaatcgtct ttgcatcaca aatcaactga tctttcatcg
    40921 cttgttgcgc ctcttcaaga gttagatgat acaactccag tacttcgtct tcatcttgtg
    40981 ctaaaggatt ctcgaccttc tctacccctt gtgcatgata aatatgaagg acttcatttg
    41041 caaaacctgg tgaaagatac atcgaagtaa gatggctcag cgacttcgca cgatagccag
    41101 tttcttcttc taattctcta gctgctgtca tttcgggatt ttgtccttct cctggatcga
    41161 tttttccagc tggaatctcc aaaatcactt tttctaaagg ttttcgaaat tgtttgacaa
    41221 gaagcagacg atcttgttcg tcaaaagcaa tgatcccgac accgccagga tgaaatacca
    41281 gttctctctt cgaagttcct ccatctggca aacgaacttc gtctacagca acatcaataa
    41341 tttttccgct atagatttct ttgcgactga ttgttttttc ttcaaattgc tcattgttca
    41401 gcatatcttc tcctgctttc tttgtaatca taactgcttt tttttcattt ttcaattttt
    41461 ctcaaaaact ccttattagt ttaccataga taaaccttag attttctcta aatatagaaa
    41521 atccttcttt agtccgatac tctttctagt agtccgtatg ctaaaataag tatgtaatcg
    41581 aataacgaaa agaattcaat actcaacgat aaatgacatg gagggtttat tatgataaaa
    41641 cgaaattggc cgtggcttct agcattggtc ttgctatttc tctttgtccg aaacaatagt
    41701 ttttcttttg ttctaggact tttattgata ggtgtagttt tagttttgtg gggactcttt
    41761 ggttcgcgca ggaaaaaggg aaaacaagaa gaaattcctg cactgactga cgaacttgaa
    41821 actcactatg aaaaaagcgg tatgacagcg aatgaaattt cattttttcg acaaacaatg
    41881 aatcaaacaa aaaatgagat caatcaattg caaatgaata tgcagcagac agccaaactt
    41941 aaagcaatcg atctccgcca tgatccagtc aaagcagcga aagctttatt caaagaattg
    42001 gtgaaagaac caaaccgact gcatgaagca agtcagtttc tttatacgca tctgccgaat
    42061 ctagttgatt tgacaaataa gtataatgag atcaatgacc atgagatcaa aaacaaacag
    42121 acctatgaaa aactagaaga aagcgcgcag atcatcgacc agctgtcagc tttaatcgca
    42181 caagattatc aaaaattcgt tgctgaggat ctagatgata tcgacgtaga gatatctgtt
    42241 gcgaaacaga gcttaaagcg tgataataaa tatgaaccag aacaaaagga ttaactcttt
    42301 tgttcataaa agaagactcg gaacattcag atgatgtctg gctgtttcga gtactttttc
    42361 taaagtagag acattcatgt aagaatcgag aacagattca acaaggagga attttttatg
    42421 gatcataaac cgactgaaac aaaagatgtt acaccagtta acgatacact tgaagattta
    42481 ttgaacaacc cgttttcaac tccaacagat acgctgacca cttcacaaca agcggagatt
    42541 gatcagctcc aagagcaaca gacagctgct cgtttaattg acaaactacc ggcggaacgc
    42601 caagaacaag ctaaacagct agcagcaaaa atcgatgcta atgatgcaca gtctgtcatc
    42661 agctacggat cggctgccca agcaaaatta agtgaattct cacaatcgat gttgaatcat
    42721 gtgcaagcac aagatattgg tcctgtagga gattccttaa ctgaactgat gtatcgtctc
    42781 caagaagcca atcctgacga actgcgtgcc ggagaaggga acatcttcca gcgtgtcttc
    42841 gggaaggtca aacaatcgat ctatgaagtg acagcaaaat atcaaaagat tggtgcacaa
    42901 attgacaaga tttcagtgaa attagataaa gaaaaagacg gtctgctaaa agataatctg
    42961 atgttagaac agctttacca gaaaaacaaa gactactttg atgcactgaa tatttatatc
    43021 gctgctggag aattgaaaat ggaagaactt caaacaacga tcattccaga agcgatgaaa
    43081 agagcagaag aaactggcga tcagatggat gttcagattg ccaatgatta cacgcaattc
    43141 ctagatcgtc tggataaacg tacgcatgat cttcgcttag ctagacagat cacgatccag
    43201 caagcaccac aaatccgttt gatccaaaac acaaatcagg ccttggctga aaagatccaa
    43261 gcatctatcg ctacagccat tccgctgtgg aaaaaccaag tcgtgatcgc attgaccttg
    43321 cttcgtcaaa aagatgcagt aactgctcaa cgccaagtct ctgaaacaac aaacgactta
    43381 ttgaagaaaa attcagaaat gctgaaaatc tcagccatcg aaacagcgaa agaaaatgaa
    43441 cgtggaatcg tggatatcga gacccttcaa accactcaaa atgatttgat cgaaacaatc
    43501 caagagacat tgcgtatcca aaaagaagga aaagaaaaac gtcgtcatgc agaagtagag
    43561 cttggacaca tggaagaaga tctgaaacaa aaactgttgg atttaaccca atagatcacc
    43621 tttcgcttgt tactaaaaca aacgcccaac aacagtttat tacaactgtt gatgggcgtt
    43681 tttcttatct ttcttctaac ttctccattg gagtctattt ctcattcatc ttgctgtgtc
    43741 catagccata gccaaaataa atgatcagtc caataaccat tacgataccg aacacgatcc
    43801 atgtcacagt ttgcagacga agcatcaata caatacaagt caagatggag acgattggca
    43861 atagcggaac gaatggcact ttgaattctc cagcttttgg tttgccaaac atttttctca
    43921 acttcagtaa gcctagacta acaagcatca aataggcgag cgccatgata ttcgttagtt
    43981 ccgctaatac attcaatggg aaaaatccgg caaagaatac agctgccaca ccagcggcat
    44041 aagtcgcttt tttcggtgta cgatgctttt gatcgatttc tgtcataaac ttaggaagta
    44101 agccatcctt gctgacagca aacagtaaac gagcaagtga atacatcatc gagatcgtta
    44161 ccgtcagtag cgttaaaatt gcccctacag cgatcaccgc gcccactgtt ccatgtccta
    44221 catacctcat tgcaaaagcc actgggtcat tgactcctag ttcagtatac ggaacgattc
    44281 ctgtcaagat cagcgtcacg atgatgtaaa ggacagtagc aatcagtatc gaaccaatga
    44341 ttcctcttgg cacatctttt tgcgggtttt tgacttcctc ggctgccatt gcaacggcat
    44401 caaatcccaa gaaagcaaaa aacacaagag ctgcaccatc tagcacaccg gaaaaaccaa
    44461 aaggcatgaa tggctgccag ttatcaggtt taacgaaaaa tattcctaca atgataaaca
    44521 acgcgatgat accaaatttg acatatacca tggcattatt caaacgtaat gctttcttgg
    44581 cttcaagcga cacgatgtaa gtgacgaata tcactacgag caccgcaatc aagtcaatgt
    44641 atgtaccatt ttccggattg tacccgccag ttaatgcttg tggaagttcg gcccctaaac
    44701 ttttcaaaaa accttgcata tagccagacc atccggaagc aacagaggaa accgctagta
    44761 aaaattcccc gatcaacaac caccctgtca gccaggcagc aaattcacca aatacaacat
    44821 acagataggc atatggccca ccaatcactg gcactcgcga agcaaattct gcgaaactta
    44881 gtccagacaa aatgacaacg attgcagcta agacaaatga aagtgacagt gctggaccag
    44941 cattttgatt ggccgcaacc cctgtcacca caaatattcc cgtaccgatg atcgcaccaa
    45001 ttccaagcat gatcaaatca gacgttttta gttctttttt catctcactc gtatgattga
    45061 gattgatctc tttcttacga aacaaatcca ttgaagttcc tccccatttt aggttggaaa
    45121 acagcgatta aactgttttc atatacccta aaaggatacc acctaaaatg actaaaaggc
    45181 aaccaacaat aacataaatg agctcttttt tcgtttttct ttcgccaagg atgaaaatcc
    45241 cacctaaagt agagataatg atccccattt gtgaaagtga gaagccaaca gctaaaccaa
    45301 gtgatttgac tgttagaagc atgcagatgt ttcctaagcc ccataataat ccacagatca
    45361 tgtttttcca cacaaactga tcgactttaa ctttacggaa agcaaagaag cttgcgccta
    45421 agatcattcc gatactttga ggtaagataa ttgacatcgc atccaaattc gcccagttga
    45481 cgatgatggt atatacacca taaccaatcg tagagaagat caatgctcta aaacccttac
    45541 caaaatcaag cattttatta tctgtatcta tttttccttc gtcatcttgt cgggcagtca
    45601 aatacgcacc gcttacaaga agagctaaag caataatacc gtatacataa tctttcgttt
    45661 gtgtccattc atggaagaaa acggctcccg caatcgtatt caaaattaat tgaaaaccag
    45721 tagacaatgg tagccctaca gaaacaccca tgtacttcat tccatggaac tgtccatttt
    45781 gtccaacact ccaagctaag ccggataaaa atccgatcaa gaaaatccaa ggggtgatta
    45841 caggactaac aacgaaaaag acaactaaag aaaacagaaa tgcaccgatc gtcattccta
    45901 gtgtttgttg attggcatcg ccaccaattt taccacttac taaaccaata ctaccccatg
    45961 ccaacatagg gactaatgct attaaaattt ccataaccaa tctcctttta tttcacatga
    46021 taagaaactt atcagcgaaa acgttaacaa cacaagcact ttttttcgtt tctaacgatt
    46081 ttctaacgtt tttcattata aaaatttaag attgggaaaa ataaagtcat tgttgtccct
    46141 tttccttcag ttgattcagc cgtcaaatgg atacctaatt tttcggccag attttttgct
    46201 aaataaagtc ctaatcctgt tgaatgtgtt ttgctaagtc gaccatttct cccagtaaat
    46261 cccttatcaa agatccgttt caagtcttcc gctgggatac cgatccctga atctttaact
    46321 gaaaggctga ctccttgcgc ttccttttct atgctcacaa tgatgtttcc gtgatccggc
    46381 gtatatttga tggcattact aagcaattgg ttgaagataa aagcgatcca tttagcatcg
    46441 gtcaaaacag tatgatcctc accaacgatc tcgtagcgaa tatttttttg gataaaataa
    46501 tttgcctgac tgcgtatcac aggctgaatg attcctttta gtccatattc ttggatgagg
    46561 tagtcccgcg agaaactgtc gagtcttgca taatacaaaa cttgttctac gtattcatcg
    46621 atttttgata attcattttc tagtaatgta tacttttgat cgtcaatatc gaactcgatc
    46681 gaacgaacta gcaatttaga agcggaaagt ggcactttga tttcatggac ccatgagtca
    46741 atataatctt tttggtcttg ttgattactg attgctgatt gcattacttc ttggtgttca
    46801 cggatcagct gattgatata ttcttctacc agtttttctt cttctgtcct cccaccactc
    46861 aaataatttt gcaaagggga agttttttgt atgtcggcta attttcccca ccatcttctc
    46921 ttgctcaagt aaccacccag cagataaaaa atcagaaaga cgccctcaat caaagctaaa
    46981 taagcaattg tgctcaaatc aactttgatg tttggcgcca gccacatcac aaagatcgtc
    47041 aatgcaataa aaaacagcca tcccaagatc aatgtccact gatctttcaa atatttaaaa
    47101 aaattcatct taaccgctca tcctttcagg gaacgatata tccctgtcct acttttgttt
    47161 cgatatatcc ttggatacct gcctgttcga tttttcggcg taaccgattg atgttgactg
    47221 tcaatgtatt gtcatctaca aatcgttcgt catcccacag tgctcgcagc aatttttccc
    47281 gacttaagat ctttccattg tgcttcatca aaataaataa tagacgatat tcatttttgc
    47341 tcaaatcaat gatctctccg ttgatttcca tacttccgtt gtcaacattc aacgtaatgc
    47401 cattgtggct catcatttca ctagataatt ctgtgtagtt gtaagaacgg cgaagtaatg
    47461 cattgatttt tgcaatcagt acatcgattt ggaaatgttt tgtcacaaaa tcatctgccc
    47521 ccatgttcat agccatgatc atatccatat tcgtattcct gctggagata aaaatgatcg
    47581 gtactttcga tacttcacgt attttttgac accaataata gccatccaaa acgggaagat
    47641 taatatctag taatacaagc tgtggttctt ctctttcaaa gtctgagaac acttgattga
    47701 aatcggtcgt tccaaaggtt tcaaattgcc atttctcaag ttcctccatg atcaattgtc
    47761 gaatgatctc ttcgtcttcg actaccatga tttttgccat aaaaaatccc tccatctttc
    47821 ttcttgctac tacaatatca aagaagccct tgtgaaacaa gttggcttac ctggaaaatg
    47881 tcattttagc aaacgttaaa aaaaactgga aatatgcgat ttaatcgcgt ttgtctcttc
    47941 caagcagctt aaatttatta tgttattctt aataattggt ctattatctg ttatttttct
    48001 ttcgttgttt ttgtctttta aattttcgat aacaccaata accgaaaagc gttagcacta
    48061 gcaatatacc tagaaggagt ataagtaatc gataaagatg gtattttttt gtctgttcta
    48121 tctttgaaga gacttcttct gtaaagggaa ctcgtcttcc tgtcactagt aatcggtgag
    48181 tgttcacggt gtaaggtgta caagtgataa gtgtgactag atcctgcttt tctctaattg
    48241 ctaatgtatt tgtttttgtt ggaaggacaa caattttctc aacgacttca taagcgagca
    48301 tccgaccata cacttcaaga tagaatcggt catcttgctc catttcttca agatccgtaa
    48361 agagtttttt ctcagcaata ccgctatggg cggtaatcac ggaatgtgta ctctctcctc
    48421 cagttggaaa agaggtgcct tgcaggactg tcgctcctct atctaacaaa agatcattcg
    48481 tttcatcaaa taaaggcaag ctaacattga ttttcggaat atagatggct ccgatcatat
    48541 gttgttcgta atattctttt cctggatttt ggacatttct aaccgcttgc tcaaaaggat
    48601 ctttgacttg tcccattcct gggattactg atgtatgagc aagcgtctga tttttctttt
    48661 catgcactgc taattgttgc tcatgttttt cttctttatc gcgttcaagc tgcttttgat
    48721 aattctcgat ccttctttga tccaaataat tgctgagagc atctgctaaa aatggatatg
    48781 taaaaactgc agctccggca agaaacatca ctgccataaa taattgtaat aaaagactga
    48841 tttgggtttg aggtctatta cctattttct ttttcatttt cttcaccttc ttatttaaaa
    48901 aaactgcagc aacctttata aaaccgattg ctgcagctta tttttgttgc ttatacttca
    48961 gacttcattt tagatttacg gtaccagctg tacgctccaa tcatcaaact tattccgatt
    49021 agtaagaatg ccaagagccc gttcccacca gtagcaggaa gtgacccgcg tttcatattc
    49081 ggtactcttt ctggccctgg attttctact cctacgatct gaatttcttc attatagctt
    49141 ccataagaga tgataaattc agtaaaggct gcctcacctg ttggaagtac ataaccttct
    49201 ggcgccatgg tctctttcat ttgataggtt ccataatcta acccttgaac ctcaaagtat
    49261 ccatttccat ctgcgacaaa ttctgttgct tgtccgcttg ttgcccactc aattctatct
    49321 gctcctgatt cataaacagc taaaggcgac tcccctttat aaaatattgc gtattcagaa
    49381 cggtcttcat tccacaattc gaatcttgca tctttaagca attcactgct tgatgcatca
    49441 tatttttcaa actttcttcc acctgttgtg actttctctg gcggctctac tccttcttca
    49501 taatcaaatt catcatttcg tccgatttca ataaccgctg tgttgttatg gaaatcatcc
    49561 gcttctagtt ctgtggaaac cttcaaatta tacgtgatcg ttaaatctcc tccacgtgca
    49621 tctgctaatc tacctaaagt atctactttg gctactccat tttcttctgt caaaatcgtc
    49681 acgacaaacc cgttgcttac tacttctact atataatctt gtccttttgt taaaatcgtc
    49741 tcgccggctc gcacttctat ttcctgatca taataagtta gaccaactgt aggcgtatct
    49801 gtgattttgt aatttttgat aacagcgctt ccgttttcaa ggacagaatc gatgaaataa
    49861 ggaataggtg ctgtgatcgt gtaagaagcc gtttttcctc tttctagatc aatataagaa
    49921 atcgtttctt gttctccagc ttcattaata atcgttactt gtctaaggtc gctttcctct
    49981 acattcatct gtttatctgc ttctctgatt tcgtttttcg gatacaaatg cacatctgta
    50041 ttgtatgtgt ctttccatgt agaaccatcc cacacgccat ccaccatatc aggcatcatc
    50101 actggcatca taacaaccat tggagacgcg attctggaaa tatgagctgg cgaataagtt
    50161 tctaagaaaa gatagacttt atctctagaa gaaggtgctt cttccgtcac ttggacggta
    50221 gagaataccg cttctccagc ttcattcgtt gtttgtttgt caatacttgt cagtcgatat
    50281 tttaaaaacc aactttctgt gtgccgtttt tgaatccatt caatcgcttc ggcagaatta
    50341 agaccgtctt ctcgttccgg tgttaaagga ttatctcgaa tcaaatcgta atatacttcc
    50401 gttacgtcaa acaaatcaaa atcgactcct ggaatatttt cttcaccaaa atccgtagaa
    50461 accaatccgc tattcggtcg ttcttccgga acagatgaga aacctttttt gtgtaatgta
    50521 atcgtcactt cacttggttt ttgtgcgact tcttcggctt tgactagttt tccgttcccg
    50581 aaaatcccta ttcccgcagt aacgagtaac agtacactca ttcccgtgac aatcattttt
    50641 ttattcattt ttttctcccc gttctttttt tattaataaa acagcaccta acaataaaag
    50701 aattcctagt aaagaaatca acgttcttgc ttcattcgtt tgcgggaata cggaccattt
    50761 tcctgattga cctggattgc ttggaccact cggctctttc ggtttgtccg ttgtttcttt
    50821 tacggtctcg ttataaacac gtggtgttgc ggattcatag gcagagactg gaactttccc
    50881 ggattctaat tcagccatct cctgtccgtt aactactaca tattgtggtt ggccttttgc
    50941 atccacccaa aattcaggga tgatgacctc gattctctta cttgcttcat ccatctcgta
    51001 accttccaca ccttttaatt cttcaaaata ataggtgcca gaaggcaaga aacgttgtcc
    51061 tgtcgtaaca aggccctctt tatccgaaat gaatttgctt acatttttgt cattcaaagg
    51121 atcattgtct gctggtttga tccattgatt tttcaagtca ttagcaggag ccatatctaa
    51181 ataatatttc cccccttcta tcatctgata tagagcaaaa acagcacctt ctaatggttt
    51241 tcctttttca gttgttcctc tttgacgtcc atacttgaag aagtatggat ctcttagata
    51301 accgacattt ttaggataga tatgaatctc ttgcagttcc tcggttgatt ctgtcgggtg
    51361 ataaattggc aaaatagcag caattgggat agctgtctga tcgatatcaa catccaatcc
    51421 aacttctgga tcaatcgatt cttcgaaaat caaataaact gcatcccgat cttggttttt
    51481 cttaggtgct ttgatacgtg caatcccgtc tcctaatccg ccaaccgtat ctttcccagt
    51541 tgttaccgaa gtccctattt ggacaagcct ttcttctgtg attagctgac ggatattgtt
    51601 tctgttcgtt tcagcgattt gctggacgaa ttctttagga gtcatgtttt cagcagcttt
    51661 tttttcatga taataatcgg tcatgtcgta aatggcaaat gtcgctccat ttagtggcac
    51721 cgtctgtgaa atgatatctg ctgtttcccc tgcttcctca gagatagcca agccatcatt
    51781 ttcatggtat tcaaattgat cgttataatc gatatctcga atcatccgtt tatgcaacac
    51841 gaattccacg acatcttccc ctgattcttc tgccgacatc gcatgtggaa gaaggactgc
    51901 tgcaagcggt agtaaaacaa gtaattgaag catcaaacac aacagctttt tcattacctt
    51961 gctccctcct ttttagattg tctgacaaac aaaccatagg ctgctcctgc aagcgccatg
    52021 aagaatgcag caagcaggat atagaataat cgtccggatc ctcctgtagc aggcaacgga
    52081 ttttcaggat cgttcccgac actaagctgt aatctgattc gatttgtctc caaaagttca
    52141 tattctaact cttgctgtag atcaggcgtc tctgcttctt cgtttggata atacgaaatc
    52201 tcaactttta gtgtacccgc ttcttttcct ggaactaccc gatcattttc tatgtcaggt
    52261 tcttctcgat aactaatttc taaaataaag taacctggaa gttttctata gctgtcaggt
    52321 gacttcactt ccttgatccg atagacccct tccaacaagt ctgaagcatt gaatagggaa
    52381 gaatcgtttg gatctggtgc caagcctccc tcgatgattt catactctcc tgcactattt
    52441 tgtttctcaa ttgaaaattc tgcgccttca agacgtcggc tattcatact gtcaattttc
    52501 aaaagttcca aatcgattgg cgctagttca tcttctaagg ttacttgtag tacaccatcg
    52561 atgatttcat agccttccgg caagggagca gtttcgtctt cgatgaccgt atcttcaatg
    52621 ataaacttac cttcttcatt cagtgcaaac tggaacactt gatcagatag ccgataccca
    52681 tttggtgcga cagattccga gacctcatat tcaccaatag acagatgcag aggttggtcg
    52741 taatttaaat cgacatactt ttctactcct acggcacgag aatagaagta tccgatccca
    52801 ggcaaacgtt tcgattcttc tggttctaac ggattaccag tgtatgctcg atacagcggg
    52861 aaggaagaat cccccacttt cctgatatcg aaacctgcac catctaatgt atggccttca
    52921 tggtctaatt ttctaactcg gatctcccga taatcaaacg tattgtaagc agtgaatgct
    52981 acccataaac gatcctcttc atctgttgta tacgtgagat attgccaatt ttcttcacct
    53041 gtttgcttga gttggatagt ccctatagca ttatcgtaaa gtcgcaagat ccatgtgtca
    53101 ttttcatcag gttctttgaa accttctggg ttctggctct caatgatttt gtattctgca
    53161 tagttggtag tttcttcact atccttataa acaaatgaat ctggctctcc gattggatga
    53221 ataactttct caccatccac gattacatat ttcccgtctt catctactga atagaacgtg
    53281 agtctccctt tctcttcctc tacttcgttc acaccagaaa gccctttcgc tactggatat
    53341 ccgatttcca gtccgttacc atctgtttca taaagttcaa actctgcgcc attgattggc
    53401 atattactgc cttcaattag tttattgata ttcatgtgga ttggcttgaa ttcatttcgc
    53461 atttccagtt tgacatacaa ctcatcatac tctgtgcctt ctatgttagg ctcttgtaca
    53521 acagaaagct tgtgatattc tccttcataa taggaattcg gatctttacc ttccggtccg
    53581 ccgactctcg aaccagatgt atattcatct acaagctcgt agtgacctaa catctcatct
    53641 tcgttggctg catatttttt gatttggaat tgatacgtct catctactaa ctgataacgt
    53701 ggtggtccag cgatctctct gatccaaaat atgtcgctga ctgctccagt ttcatctcct
    53761 aaaatcggca tcttcgtttc aaagatcgct attccgtccg tggtagtttt acttgtttcg
    53821 attggttcgg cttccccact ctctggattt tggtcatata atgcaaattc gactccagcc
    53881 aacggctcgc cattttgacc cttcttgctg acttggaaat tacggccttt atgttcgtaa
    53941 cgaatggaag aagatgggaa atacatccgt ccagtagtga tatcattctc ataatcctcc
    54001 aggttctgaa tataggccat attgttcact gtgcaaaaat ttccgtcttg agctcccgca
    54061 tcaagtttta cttggtactt gatcctgacc atttcccctt cacctaaaga aatcggagaa
    54121 aatttataag cttggttttc ccgtccgaca tacgttgtcg gagtcgccac tacttctggt
    54181 ggggcttgtc catgacgttc ttcatcccat atttctggct cttggtactt catgccgttt
    54241 tctcctggat ctagatggta aaactgaata tctgccgatc tgccagctcc aaatggtgag
    54301 acattaaaac cagtttcatc ataaagtgtg gcttgctgga tcgttctctt gaaggtagaa
    54361 gagatatcct ccaaggctgt aacaatgtca ttcttgttgt tcgcattgta atatcgcggt
    54421 gttacgccat cttcttctaa atcagcaata tttttcaata catttcgtcc aatagcatct
    54481 agtcgttgtc tcccgctaac gtttccatcg attcctaaac caatggagaa gatacttggc
    54541 gggttctctt gatacttatt tttcagccaa tgatgataag caactgtgtt gatcgcagat
    54601 gacttttctt gcgaagtagg actgccattc gtattgttat tagaagaacc atcaccaacc
    54661 cagtgagtcg ctttattatc tccttctttt acctctccat aacgatagtg tacatttact
    54721 tcatcttctg gacggttaaa gtcagatgca taggtaactg gatgagtaaa ccctgcatta
    54781 gaagtattcc cagaaaactc ctcaaaattt ctgaacaaaa cgtcattatc ttcagcaatc
    54841 ttatcttcca tcacagtcca gttgctccaa gctccattag tgctcgtacg ataacttgac
    54901 tgaatcggtg cataactgaa ggtcggtgtc ccatctccca caacgattag gattttttct
    54961 ggatttctat tttctccgcc attgtcttta tacaatgttt catagccatt tttaagccct
    55021 agtgtaagcg gagttcctcc gattggtgta cgatttattg ctgtattctc acttcccgtc
    55081 aaacgattga tatcatttgt caatggaaag atgtccgaac tgatttgctc atggttattg
    55141 atagctgtac tattatggta aaaattcacc ataccgattc gaatatccag actcgggtca
    55201 gagagcagat ctttactcat ttcgtttact gcctcaatca acgcagcatt tttagtttga
    55261 ctattggtcc cagcggttaa ttcactcata ctcgctgact tatctagaac aaaaacgata
    55321 tcgattggac tgatttcctt tttctcgccc ccgatgacat ctagatagac attgtaaagg
    55381 gttgttgcat cttcaggatg tagatcagat gctgtgctgc ttggcagaac aggttctacc
    55441 cattttttga tgtacgcccc gttataatcc aagtaactgt tttcaaaatt ccgttcattt
    55501 ccccaaagct gaacggtttg agctggaacg tttctatctt cttcgcctgc agttgatcca
    55561 ttattagtag catagtcgta atttcgccag ttcgctcccc cgtttgtata atcactatca
    55621 tcgatcaagt tctctccgtc atatggcgag cctttgtctc cttgatagcg ttcattgctt
    55681 tgtgtccaat ttcctaacac ttttgtatag tcattcgttg taaacttcgg gtagcgatgc
    55741 tgttcgtttt caacttctcc gctaggatag atatattcat aggggtcttg cgtagctgtt
    55801 ggcccaagac gctccaaaat accgttgaat aactggcgtt gaatgcgctg gagtgcttga
    55861 ccgctgggta cgattggttc gtccagcttt tccatctcat tttcttcgct acgttgaatt
    55921 tcagcggaat cttctgtatc agtttcattt tcttgtaatt cttggttatc tattctttca
    55981 tcaaccacca cttgaagagg tagttaccct tcgttcacat cggggatctt ttctgtttca
    56041 aaaatcaatg tgccggtttc tgcttctttt gaataaactt ttccgacata ccattcttga
    56101 ccatcgatcg tctcgacttt taggtcttct ccatcttcat cataggagga tagacctgtt
    56161 ccacgaacgt tttttacggt accaatcccg gcggctgccg catcgattgc taaacgtatt
    56221 ctaccttcat tggcactttc ctttttttca aaagccagat gccattcaag ggtttcttct
    56281 ttttcaatat acttcccttc aatttttgca tagtcctcat ctaagaatac ctcatcctcc
    56341 tttgtttctg ttgactcagc agctacatcc agggtcgtca tatgatagac tgactggaaa
    56401 tatggtccaa atagcaaact gacagttact aactgcaaaa gcttcaattt taaccctttc
    56461 acatccttat actcctttca aaaatatttg tcttctttca caacaatcaa caaaacaatg
    56521 cccatctaat tataatttaa tttaatttta attttaaatc aaatgatatc ctttttagtt
    56581 aaaaaacacc aattatacaa catttattat taaaattaaa ttataaaatt ttataacgtt
    56641 ctcatttaac aaaacttaag ttattaagac aaatgaataa acaactacgc tttcctcgaa
    56701 acaaaaaaat aaagcacaaa tgcgcattta cgcactcatg ctttattcgt acaattaatt
    56761 cagataacgg cagcgcatag gatgccaata acacttccta aaatagctcc tcctaaaatg
    56821 tcagtaggat aatgtaaaag taaaaaaatc ctcgaataag cgatcaaaca agcaaataaa
    56881 aaggctaata ttcctgcaac tggacttaat tcgaacaacg cagctactga taaaaaggct
    56941 agcgctgtat gtcctgaagg aaaagaagaa gtcttcggtt tacttgtgta aaggacaagc
    57001 cgacgatttt tttcataagg tcttttccgt cttgtcgttt ttttgataaa aagcaaacca
    57061 acaaaaaaat agatcaaact gccgataaga atggctagac catattctct agtatcaggt
    57121 atcaagacta aaacagcagc aaggagcaac caaataaaac caccattaga gatattactg
    57181 ataaatttca aaaaattgat ttttcgacta tccgttttcc gttgcttggc gaacttgttg
    57241 ataatactat catcgatttt agcaatcaaa cgcaacatgt tattcctcct ttttaagaac
    57301 cttttcttgc gtacgatgga taaaaagcag gacttgaaaa taaaacaaga aactgaaacc
    57361 taataaagca aaatagattg gtcctgcaaa ccagaatgcg acaagaagga tcaacgtgcc
    57421 tgccaaatag aaaagcgcgc ttttgaaatc attaaaaaac aagaaaaatg cagtaatcca
    57481 agaagcttct ttttgttcca gttgaagcaa gattttgtaa ctaaagagaa gcgcgcttaa
    57541 tagaagcaaa aacaacgtag tatacatcaa tgtatagcca attcccccac cccaatagcg
    57601 gaaaatctga taatcgatca atagaagaag aaaataaaca cttgctaaac tatcttgctt
    57661 tccataaaga gagaagttct cacgaaactt tttccagaat agtgaaccga actttttctc
    57721 ttcatttttt ttgtaatgat aaatcatata cagaactgtt cgacttgcag ttcctaatgt
    57781 gaaaacaggc aagacgcaca ggaaccatag tagctgtaaa tggataagac gtggaatcca
    57841 ttcaatgatt tctaagaaat aatcattggc ttttttacca atcgatcgat tcatcatcct
    57901 tttgaacctc ctgtcaaatc catcccttca atgaaataac gttgtgcaaa aaagaacagc
    57961 aaaatcgtcg ggatcaagac aagtgttgct cctgccatca gataattcca ttgtgtcgtt
    58021 gcttggttct gaaaaacttg caagccaatc tgtaacgtgt atttttcttg atcttggata
    58081 tataacagag gacctaagaa atcattccaa gctgcgttga aggaattgat cgcaatggta
    58141 atcaaggcag gtttcgtcaa tggaagcatc aaatgactcc aaatatacaa atgattcgct
    58201 ccgtcgattt cagcagcttc gatcaattca ttattgatcg ataagtaaaa ttgacgcatc
    58261 agaaatatat tgaacgcatt gccgaagaac gatggaacga tcaggggcaa ataagtacct
    58321 acccagccga tcttggagaa taatacatat tgagggatca tcgttacaaa ccccgggatc
    58381 atcatcgtag aaagaaccaa agcaaacatc agctttttcc caggaaaatc aagcttcgca
    58441 aatccataag caataaaaga atttgaaagg acattaccga tcactactag cacagtgatg
    58501 aataatgtat ttcttgcata gcgccaaaaa ggaaaggcgg caatcgtatc cagatagttt
    58561 tcccatacga ttttttctgg gaaaaaggtc ggaggataac gaacgatttc ttccattggt
    58621 ttcaatgaag taaacaccat ccaaagcaat ggaatgatca aaatgattcc tattactgtc
    58681 atgaggacat aacttagtat tttttttgtt tgccgattca cactggtctt tttgaaataa
    58741 tccatcattt gccgtcacct ccagaataat agacccactt aggtgcaagc ttcaaattga
    58801 caaacgtcag aaccaacacg atcagaaaca ggatcattga catagccatc gcataaccca
    58861 tatcaaaagc tacgaacgcc ttgttccaca tatgcagatt ataaaaaagc aaagaatttg
    58921 caggtccgcc tgttccattt ttcgtcatga cataagcttc ttgaaaaatt tggaaagaac
    58981 cgatcgtaga ggtgatcaca tcgtaaaaaa taataggagt gattaatggc aaagtaatac
    59041 ttttgaactt tccccaaacg cctgctccat cgatttctgc tgattcatat aaagatctag
    59101 gaacattttg taatgtagct aagtaaagta gcattgctcc tccagaactc catattttca
    59161 tcaaaatcaa cgcaggtttc gtccattgtg gatcaaacag ccaagctggt ccagggatat
    59221 ggaaccagcc cagaaatgtg ttgatcaatc ctgcagatgg agaaagcagc tgcatccata
    59281 agatgtagac tgctactcct gataagactg ccggtaaata gaaagctgta cggaatacac
    59341 tgattccttt gattttttga ttgagtactg tggctaaaaa cacactgaaa atcgtcgtca
    59401 gcggtacatt gaagatgacg aaataaacgg tgttgtataa cgatttccaa aataaatcat
    59461 cgtgaacgaa cattcttttg aaatttgcta gaccaatgaa attcatcttg gatgtcaaat
    59521 tataatcggt gaaactacca ataactgaaa aaagcatagg ccctagcata aataccaaga
    59581 acccgataat aaaaggcgag ataaataaat aggcccatct tgcttctttt ttctttcgga
    59641 tagataaacg cttcaaattt tcttgcctcc tctgtaccta gacagtcaaa aatggattat
    59701 tgattttgct tgactaagtt ttctactgct ttttgtgcat ctgccaatcc ttcttttggt
    59761 gattttgttc ctaaaagaat ctggtcaatc tgttcattca ctaatgtcgt gtaatccgga
    59821 gcatctaaag gaactggtgt gatcaccgta tttttaaagt tttcgtccgc catttgatag
    59881 atcatttttc ctttatccgt taggttgtca ttattcacta aattctcatt ggctgtcttg
    59941 ctcgccatga tatcaaaact tttttcgccg aatttttctt gtacttctgg agaagaaaga
    60001 tatttgatga attcataaga ggcctcagga tcttttgctc cgtatggtac ttccaagacg
    60061 aatccgccac cccacgacca atggcctgaa ccttcttctt tttctgggag ctgcatcacg
    60121 ccaaaatcaa aatcatccgg tgcattttcc atcaaactag agtaataatt gatattttgg
    60181 gcacgcatgg ctactaatcc ggaaataaat ggatcagata caccagaccc aaattcggct
    60241 tctaatttat tgatcgtatt tttcccataa taatcttgcc agtcttggat ccactccaag
    60301 gcttccactt tatttttagt atcaatcttg actttttcat ctttgtcaaa ccaactagtc
    60361 ccgttatctg cgtttagcgc ccatacatca gcccctaaat tccataatgg ataaaaaccg
    60421 atgcgtgtaa attcttttcc ttctttttta tctagtttac gtgctgtttc ttctaattca
    60481 tcccaagttg tcggtagatc ttgttcactg attccagctt ctttaaataa ctttttatta
    60541 taaaaaatga cttgtgtatc tgtattgaat gggatcgcat aaggatcacc ttcatattct
    60601 actgtatccc aaagctgcgg ataaaaatcc ttagaagtgt ctttttctac atatttggag
    60661 agattagttg cttgctgtgc ttctgctctt tgggcaacgg aatttatgtc ctgtacaata
    60721 acatcgggtg catttccagc tgttattgca gataaagatt tagtccagat gtcaccccat
    60781 ggctgatact tataatttac atggatctcg ttttgtgatt gattgaaatc ctcaatgatt
    60841 tcttcgatag cttcttttcg tgcaccggat ccccaaaagg accagaaatc aatatttttt
    60901 cttccatcac ttgttttttc agaagaattt gctgcacttg aactggcatc gcttgcatta
    60961 cttgatccgc atcctcctaa taaaaacaat gctgaacttg ccagcaaccc tgtaaacaat
    61021 aattttttca tattttacct ccaaatttta atgtaaccga tgccggtttt aatataacga
    61081 tatcattttg ttctgaaaat aacaatttat aaggtatgat tctaaaaaaa ttattaatga
    61141 taccaatact ttatataatt cgcgagcgct ttctttgaat tttttaatct ttcgtagcag
    61201 aatgagaatg tattaaaaat agattaggag gaattttgat gtttagacac cagaaagaat
    61261 tgcagtttga agcaaaacca gatcgtccga atccattaat cgcgaaatat ctgcaggagc
    61321 tgatcggcgg ccaatatggc gagatgagtg tagctatgca gtacctgttc caaggctgga
    61381 gctgccgagg agaagaaaaa tataaagata tgctgatgga cattgcaaca gaagaaatcg
    61441 gccacgtgga aatgttggcg acaatggttg ctcgtttatt agagggtgcg cctgttgaag
    61501 atcaagaagc agcgatgcaa aaagatccaa caatcggtgc cattatctct ggaatgaatc
    61561 cacagcacgc gatcgtagct ggcttaggac ctcgtcctgc tgacagcgtg ggcaatccat
    61621 ggagcggtgc ctatatcatt gcgagtggca acttgttagc agactttaga gctaatttaa
    61681 atgccgaatc acaaggaaga cttcaagtag cacgtattta cgaaatgatc gatgatcgtg
    61741 gcgtaaaaga tatgctgtct gttctccttg caagagatag ctatcatcaa aatctatggg
    61801 aatgtgcagt gaaagaatta gaagaaaaag aaggttcaat cttagtccca agtactttcc
    61861 cgcgtgacaa agaacgaaaa gacattgctt atgacttcta taacttctca gagggagacc
    61921 aaagtagtga aggttcttgg gctagtggca aagcactgga tggcgaaggc gaatatcaat
    61981 ggttgaaaga acctaagatc gaaggcgctg caccaaaatt agaaccagta acaccaaaaa
    62041 tgtatgggac acctccattc aagaaataaa tatctacccg tagaaacacc cgttttttgt
    62101 tccacacgct ttgtgagcaa aactgactaa agtcattaat cataaccacc cttcaaaagg
    62161 gtggttttct ctagagctat aagctcaaat caccggccag cgcctaaaga cgctggcttt
    62221 catattttat gttcaagcca tattgccttt gccagttttg cccacctctt aaaaggttta
    62281 tgtactactc cttagccctt aaaaggatcg tcttactctc gtacactcag cttatctaac
    62341 gcactatcat gtttttcttg ttcttgaatg tactttttga tggtcgcttc attttgtcct
    62401 acttttgtca catagtatcc ttccacccaa aagtgtcgat acccaaattt atattttaga
    62461 tttgcacaat ctcttgatga tctcctgaat attggctcga tattgattat aaattatttt
    62521 tcttctatac tttggtgtga atacaatgtg gtatttacac atctactttg tacgggctaa
    62581 actatttccc tttattgctc cacccgcata gcaagtggtt ttgtatttca atcgctcggc
    62641 gcgctcaatt aggtctaaag acaataaatc taaaaacccg ctgcttcact gacagaaaca
    62701 acgggttttc agaaaaaaat gaaatgaaaa agatctctta cggcaatcta ttttattttt
    62761 ttgatttttt ataaatggaa aatgcttcaa gaagtccaag aaataaagcc gtataaaaac
    62821 aagaacctat gaaatcttta tttattagat attcaacaga aatcccgata acactagcca
    62881 acaatatatt tatcagaagt gtaaaataag gatgcttttt atagaataga actagtgttg
    62941 ttttcataga ctctcctttc ttcatatttc caattaatca caaattcacg gcattactag
    63001 aaaaattaaa ggggcgcaga agtggaaaaa tactcttcga ctttccctac aaaccaggcc
    63061 atcttgtgtt taataactat accaaatcta aggtacctct aaatctaaat tccatttgtg
    63121 gcggtgacct ccaattttta actcttctat ctcccatcca gtatacataa ccttgatact
    63181 tcgaccactt atatatcgaa cacacaaata cctatccatt gcaggagtac tacctaactt
    63241 agttgctact tgcatctaaa taacagctga aaagatagga cttactctta gtaaagtatc
    63301 tgaactatta atttttaaac tatcattttt atcctcaact acatgcacat ctgttgcaac
    63361 ttcactttct gtctcatcca gataaatgat taaggaatcg ggaattgcaa tatcttcagc
    63421 tgacgctgga atagttgagc taaattagtc atcatatctt tattataaaa taaccaacag
    63481 caaaaaatac aatgaaaaac aaacttggaa ctaatgtatc attaataaat gttgaaaaat
    63541 tcagcaactc attactgtat gattttagca gcccaaccaa catataccct ataaaagcta
    63601 ataagatggt taggaatcct ttagaatttt tactcattca tagacacttc cttaaataac
    63661 ttttattata gaaggtattg taaataataa tattgacaaa aagtgactca aaataaaaaa
    63721 aaccttacat tatactggaa tgaact
//
LOCUS       DACDLM010000008        60802 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.008, whole genome shotgun sequence.
ACCESSION   DACDLM010000008 DACDLM010000000
VERSION     DACDLM010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 60802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60802
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.008"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            8..586
                     /locus_tag="IV356_000525"
     CDS             8..586
                     /locus_tag="IV356_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014243.1"
                     /translation="MNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNT
                     MGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGI
                     YLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKE
                     LMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
     gene            complement(826..909)
                     /locus_tag="IV356_000526"
     tRNA            complement(826..909)
                     /locus_tag="IV356_000526"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(873..875),aa:Leu,seq:gag)
     gene            1292..2509
                     /locus_tag="IV356_000527"
     CDS             1292..2509
                     /locus_tag="IV356_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAP9014244.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            2693..3529
                     /locus_tag="IV356_000528"
     CDS             2693..3529
                     /locus_tag="IV356_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP9014245.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            3605..4753
                     /gene="nagA"
                     /locus_tag="IV356_000529"
     CDS             3605..4753
                     /gene="nagA"
                     /locus_tag="IV356_000529"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HAP9014246.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            4974..6032
                     /locus_tag="IV356_000530"
     CDS             4974..6032
                     /locus_tag="IV356_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014372913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HAP9014247.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            6051..7070
                     /locus_tag="IV356_000531"
     CDS             6051..7070
                     /locus_tag="IV356_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HAP9014248.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(7172..7888)
                     /locus_tag="IV356_000532"
     CDS             complement(7172..7888)
                     /locus_tag="IV356_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAP9014249.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(7857..8642)
                     /locus_tag="IV356_000533"
     CDS             complement(7857..8642)
                     /locus_tag="IV356_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAP9014250.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(8633..9382)
                     /locus_tag="IV356_000534"
     CDS             complement(8633..9382)
                     /locus_tag="IV356_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HAP9014251.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            9680..10204
                     /locus_tag="IV356_000535"
     CDS             9680..10204
                     /locus_tag="IV356_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014252.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            10220..11719
                     /locus_tag="IV356_000536"
     CDS             10220..11719
                     /locus_tag="IV356_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HAP9014253.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(11807..12409)
                     /locus_tag="IV356_000537"
     CDS             complement(11807..12409)
                     /locus_tag="IV356_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP9014254.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            12513..13469
                     /locus_tag="IV356_000538"
     CDS             12513..13469
                     /locus_tag="IV356_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HAP9014255.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(13774..14730)
                     /locus_tag="IV356_000539"
     CDS             complement(13774..14730)
                     /locus_tag="IV356_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP9014256.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            14904..15464
                     /locus_tag="IV356_000540"
     CDS             14904..15464
                     /locus_tag="IV356_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014257.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            15457..16281
                     /locus_tag="IV356_000541"
     CDS             15457..16281
                     /locus_tag="IV356_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HAP9014258.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            16291..16908
                     /locus_tag="IV356_000542"
     CDS             16291..16908
                     /locus_tag="IV356_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HAP9014259.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            16926..17609
                     /locus_tag="IV356_000543"
     CDS             16926..17609
                     /locus_tag="IV356_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAP9014260.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            18292..19575
                     /locus_tag="IV356_000544"
     CDS             18292..19575
                     /locus_tag="IV356_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP9014261.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            19591..20478
                     /locus_tag="IV356_000545"
     CDS             19591..20478
                     /locus_tag="IV356_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP9014262.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            20495..21331
                     /locus_tag="IV356_000546"
     CDS             20495..21331
                     /locus_tag="IV356_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP9014263.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            21334..21957
                     /locus_tag="IV356_000547"
     CDS             21334..21957
                     /locus_tag="IV356_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014264.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            21954..23246
                     /locus_tag="IV356_000548"
     CDS             21954..23246
                     /locus_tag="IV356_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP9014265.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      23605..23702
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            23818..24399
                     /locus_tag="IV356_000549"
     CDS             23818..24399
                     /locus_tag="IV356_000549"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HAP9014266.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            24402..25709
                     /locus_tag="IV356_000550"
     CDS             24402..25709
                     /locus_tag="IV356_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HAP9014267.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            26125..26613
                     /gene="purE"
                     /locus_tag="IV356_000551"
     CDS             26125..26613
                     /gene="purE"
                     /locus_tag="IV356_000551"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HAP9014268.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            26597..27730
                     /gene="purK"
                     /locus_tag="IV356_000552"
     CDS             26597..27730
                     /gene="purK"
                     /locus_tag="IV356_000552"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HAP9014269.1"
                     /translation="MINLVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVS
                     DCPAAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTD
                     LLAITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKG
                     QYVLKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHN
                     NILHETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRP
                     HNSGHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENK
                     PDWQFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            27743..29038
                     /gene="purB"
                     /locus_tag="IV356_000553"
     CDS             27743..29038
                     /gene="purB"
                     /locus_tag="IV356_000553"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HAP9014270.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(29218..29595)
                     /locus_tag="IV356_000554"
     CDS             complement(29218..29595)
                     /locus_tag="IV356_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014271.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            29851..30579
                     /locus_tag="IV356_000555"
     CDS             29851..30579
                     /locus_tag="IV356_000555"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HAP9014272.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            30579..30833
                     /gene="purS"
                     /locus_tag="IV356_000556"
     CDS             30579..30833
                     /gene="purS"
                     /locus_tag="IV356_000556"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HAP9014273.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            30835..31506
                     /gene="purQ"
                     /locus_tag="IV356_000557"
     CDS             30835..31506
                     /gene="purQ"
                     /locus_tag="IV356_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HAP9014274.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            31507..33729
                     /gene="purL"
                     /locus_tag="IV356_000558"
     CDS             31507..33729
                     /gene="purL"
                     /locus_tag="IV356_000558"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HAP9014275.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            33714..35153
                     /locus_tag="IV356_000559"
     CDS             33714..35153
                     /locus_tag="IV356_000559"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010768528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HAP9014276.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            35185..36228
                     /locus_tag="IV356_000560"
     CDS             35185..36228
                     /locus_tag="IV356_000560"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HAP9014277.1"
                     /translation="MANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGFGGC
                     FDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEPLYF
                     LDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFAVGI
                     AEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKKTLG
                     EELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSWPIL
                     PIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGKVIA
                     KEKHRVVFIGEER"
     gene            36225..36803
                     /gene="purN"
                     /locus_tag="IV356_000561"
     CDS             36225..36803
                     /gene="purN"
                     /locus_tag="IV356_000561"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HAP9014278.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            36800..38335
                     /gene="purH"
                     /locus_tag="IV356_000562"
     CDS             36800..38335
                     /gene="purH"
                     /locus_tag="IV356_000562"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HAP9014279.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALVFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            38351..39625
                     /gene="purD"
                     /locus_tag="IV356_000563"
     CDS             38351..39625
                     /gene="purD"
                     /locus_tag="IV356_000563"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HAP9014280.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            39747..40661
                     /locus_tag="IV356_000564"
     CDS             39747..40661
                     /locus_tag="IV356_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HAP9014281.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(40794..42359)
                     /locus_tag="IV356_000565"
     CDS             complement(40794..42359)
                     /locus_tag="IV356_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAP9014282.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(42352..43803)
                     /locus_tag="IV356_000566"
     CDS             complement(42352..43803)
                     /locus_tag="IV356_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP9014283.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(43817..44833)
                     /locus_tag="IV356_000567"
     CDS             complement(43817..44833)
                     /locus_tag="IV356_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP9014284.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            45053..46141
                     /locus_tag="IV356_000568"
     CDS             45053..46141
                     /locus_tag="IV356_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAP9014285.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            46195..47721
                     /locus_tag="IV356_000569"
     CDS             46195..47721
                     /locus_tag="IV356_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HAP9014286.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            47723..48928
                     /locus_tag="IV356_000570"
     CDS             47723..48928
                     /locus_tag="IV356_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP9014287.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            49185..50162
                     /gene="guaC"
                     /locus_tag="IV356_000571"
     CDS             49185..50162
                     /gene="guaC"
                     /locus_tag="IV356_000571"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HAP9014288.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            50426..51850
                     /locus_tag="IV356_000572"
     CDS             50426..51850
                     /locus_tag="IV356_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAP9014289.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            52311..53420
                     /gene="pdhA"
                     /locus_tag="IV356_000573"
     CDS             52311..53420
                     /gene="pdhA"
                     /locus_tag="IV356_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HAP9014290.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            53423..54400
                     /locus_tag="IV356_000574"
     CDS             53423..54400
                     /locus_tag="IV356_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HAP9014291.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            54425..56068
                     /locus_tag="IV356_000575"
     CDS             54425..56068
                     /locus_tag="IV356_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005236379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HAP9014292.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            56076..57482
                     /gene="lpdA"
                     /locus_tag="IV356_000576"
     CDS             56076..57482
                     /gene="lpdA"
                     /locus_tag="IV356_000576"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HAP9014293.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            57644..57919
                     /locus_tag="IV356_000577"
     CDS             57644..57919
                     /locus_tag="IV356_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HAP9014294.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            57925..58692
                     /locus_tag="IV356_000578"
     CDS             57925..58692
                     /locus_tag="IV356_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HAP9014295.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            58860..60689
                     /gene="typA"
                     /locus_tag="IV356_000579"
     CDS             58860..60689
                     /gene="typA"
                     /locus_tag="IV356_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HAP9014296.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLNRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
BASE COUNT        19579 a        10445 c        13360 g        17418 t
ORIGIN      
        1 tttagacatg aatatcttat ttttattgct atttttctta attttccttc taacatatag
       61 gaaatgtcaa aactattatg tgcgtatatt gactgcatta ccgtttttct taaacctgat
      121 tatttatttt ggtaatacaa tgggtcaaag ctttacttac gtcaatggaa ataaaagggc
      181 aatgatttgg agtagtagta acctgaataa tctctttaca gagttaggaa cgaaactgtc
      241 acttttttat ccaggtactt ggatagctac tttagtagtc ttggcattat tactatgttt
      301 aattgttgga atttatttaa gttttgacaa taagaaaact tctatttttt tagttatttt
      361 gatgataatg ggattttgtt caaggttaat tatgggattt tctcccacag tatgggcttc
      421 cggaatgcgg acgtactata tactttatgt tgttatcgcc atcttagtac taatggcagt
      481 taaagagcta atgaaaagca tgagtgtaca aaaaaatgaa tttatgcaat ttggattaac
      541 cgtgcttggt atttgtacct ttataataac ggtgataaac agataatata caaaaaatcc
      601 ctcgctttag tattaggtga gggattttac tcgtttttcg attaattgtt ttaacacttg
      661 caagtttcta cgagtagctt gtttccgacc ttcatatact cacctcaggc tgtttacatg
      721 attgtacgtt ctttttgtaa aggatacagt gatatgtata taatggcata aagaaacgtt
      781 caaacaaaaa aactcgtgaa gcaaaattaa cttcacgagt tgtagtgcag atgatgggac
      841 tcgaacccac acgagctaac gctcacatga ccctcaatca tgcttgtctg ccaattccaa
      901 cacatctgcg taataataac acactaatga tagcgaggtt ttacatagtt gtcaagctca
      961 aaaatgggag gacttattaa gatggagaaa tatgacggag aattttcagg actgggaatg
     1021 atcttaggtg tattgattgg acttgcattc ggacgttttt tgcttggttt tatgctagga
     1081 atcatttgtg gaattgcaat ggattgggca gcgaatctat ggaatgacta tcatgacaat
     1141 taagttctca acgcttgttt gtgttttttt aatacttacg tttttcctaa ataagtggca
     1201 aaattttcta ggatggagta tgatattgaa atagtaaata acaaaaaatt tggaaagttc
     1261 taactttttg aaatgaggga ttggctaagt gatgagagaa tttgaaaaat ccaacaaatt
     1321 agaaggtgtc agttacgatg ttcgcggtcc cgttctagaa gaagcggagc ggatgcaaga
     1381 agagggcatt agtattttaa aattgaacac gggaaatccc gcaccttttg gatttgaagc
     1441 accaaacgaa gtcattcgtg atttgatcat gaatgcccgt gactcagaag gctactcaga
     1501 ttccaagggg atcttttctg ctagaaaagc aattgagcaa tattgccaac tgaaacattt
     1561 tccgaatgtg acgatcaatg atatctacac cggcaacgga gtgagcgaat tgatcacgat
     1621 gtgtatgcag gggttgctgg acaatggaga tgaagtactg gttccaatgc cggactatcc
     1681 gttgtggacg gcttctattg cattagctgg aggcacacct gttcattata tttgcgatga
     1741 agaggcagaa tggtatcctg atattgatga tatcaaatca aaaataacga gtcggacaaa
     1801 agctattgtt atcattaatc ctaataatcc tactggggca ctttatccaa aagaattatt
     1861 agaagaaatc gttgaagtag ctcgacaaaa taacctgatt atttattccg acgaaatcta
     1921 tgatcgctta gtgatggatg gtctagaaca tattccgatt gctacattag cgcctgattt
     1981 gttcgttgtt acgctgaacg gtctatccaa atctcatcgt gtagcaggat ttcgagtagg
     2041 ctggatggtc ctaagtggag ataagtcaca cgtcaaaggc tatatagaag ggctgaatat
     2101 gttgtcctcc atgcgtttgt gttccaatgt attgtctcag caaattatcc aaaccgcgct
     2161 aggcggttat caaagtgtcg atgagctgct cctgccaggc ggaaggatct atgaacaaag
     2221 agaatatatc tataatgcaa tcaatgatat tcctggtctt tcagccgtaa aaccaaaagc
     2281 tgctttttat atattcccaa aaattgatac aaagcgattc aatattttgg atgatgaaaa
     2341 attcgttttg gactttttac atgaacatca tattctactt gtacatggtg gtggatttaa
     2401 ttggaaccag ccagatcatt ttcgaatcgt ttatcttcct aaaatggatg atttgaaaca
     2461 aacagctaag aaaatgagag aattcctagc aacctatcgc caaaaatgat tttaaaaacc
     2521 aaatttttca gtaggagggc cacagacaaa cacactgagg ctctctttct agtggagttt
     2581 tcttaaataa ctaaagtata ttatttagtt gcaagtcttt tcttgaagtt tgcgacttcc
     2641 taaagtaaaa tacgaataga atgcgaatac gcatattttg gggaggatac ttatggaaac
     2701 gttaatcgag tcctttggaa cgatcattaa agagattcga aaagaacaaa aaatgacgca
     2761 aaaaatgctt tcgcatgata tttgttcaca aagtgtatta agtcggatcg aaaataatga
     2821 ggaactgccg aatgtattgg tgatgatgca gatttgtcaa cggctagggg taacgattga
     2881 tcatgtgatg aatctctctc gaaaaactac tcggacaaac gataaattat ttgaactgtt
     2941 ggatagttgt ttccaaaaac gtgattatcg gaagttagaa caagtactaa aatcttctga
     3001 tatttctgaa aatctgtatc aagcaactga ctttcaacgc tattattatt atctcggtgt
     3061 ttgcgaattc acgttgcgtc aaaatatctc tcagtccctt tattatttga aagaagcatt
     3121 aagctactct agccaaaaag aaagaatcca tgtttctgac acagaaatac aactgattag
     3181 ttgtatcgga aaaatatatg gtgtggcagg aaaaacggct gaagcacgct actatttgag
     3241 tcgaagcatc caactgctgc atcaatcagc tgatgaacga tcaaaaagtg aattttcgca
     3301 aattttttat aattatggaa atttcttatt ccatcaaaat gaaatcgacg aagcgttaga
     3361 acaggtgaat caaggaatct attgggctca agagaagaat agctactatt acctcaatga
     3421 tttatttgtg cttaaaagct taatatacaa gcgtaaagaa gaaccagaaa gagcagcatt
     3481 ctatgaaggc ttagcacaag ctgtgaaaca aatttcaaaa aatttgtaaa tggtgtagac
     3541 cattcttgac ttcttctcta aataagagta ctttagaggt agaaaaacaa agggagagaa
     3601 tagaatgaga acttttatct atgctgacaa attcttttta gcgtcaggtg tcaaacatgc
     3661 aggctatctt gaaattaccg atggactttt tggtgaatac accaaagaac tacctgaggg
     3721 agaagtcaac atcattgacc aaagcggcaa atggattgct cctggtttgg tagatacaca
     3781 tattcacggc tatatgaatc atgatgtaat ggataatgat gcagaaggca tcaaagtgat
     3841 gtctgaaggt ctgttatctt gtggagtgac ttcattttta ccaacaacat tgacgtcaag
     3901 caaagaacgt ttaaaagatg tagctgagac aatcggcaaa atgtatcagg aagcaccagg
     3961 agctaaaatc aaaggaatct attttgaagg tcctttcttc acagaagaac acaaaggggc
     4021 acaaaaccca agttatttcg gggatcctga tttggatact ttccatgaat ggcaagaagc
     4081 ttcaggtggt ttaatcaaaa aaattgcttt agcaccggaa cgtcaaggtg tagaagagtt
     4141 tgtcaaacaa gtgactgaag aaggagtagt tgtttctcta ggacacagta atgctacact
     4201 agaagaagcg caaaaagctg ttgaagcagg cgcaagtgta tttgtccatg ctttcaatgg
     4261 tatgcgtgga ttgaatcatc gcgaaccagg tatggtgggt gcgttattat ctttagaaca
     4321 tgtcttttct gaattgattt gtgatggcca tcatgtacat ccaaatgctg cgggaatcct
     4381 aatggaaaaa gcaggacatg atcatgtcgc attaattaca gactgtatga tggccggtgg
     4441 gatgcctgat ggaaattaca atttaggcga atttccagta gtagtaaaag aaggaacagc
     4501 acgtctagaa tctggcaact tagctggaag tatattgaaa ttgaaagaag caattaaaaa
     4561 tgttgtagac tggggattag caacaccaga acaagcagtc atgatggcta gtctgattcc
     4621 agcaatcagc tgtaaaatcg atgatacatg tggaaaaatc gctcaaggac gcgatgcaga
     4681 ctttatcgta ttgaaccctg atatgacatt ggaagcaact tatctagatg gcgtggaacg
     4741 tttccacgca taatataatt taagttaacc ttaaaactaa acttcttaag tttggtttta
     4801 aggttttttt tgtgttctag taaaaatcac tttacataag tttcaaaagt ttctttaatt
     4861 tcctattgtt caataagtaa caatgtaaag ataaaattaa aaatgttaat acgtattagc
     4921 aaaataaaag ctttttttat tgtgaataaa tgaacataat taggaggaga aagatgaact
     4981 tatttgacat ttttcgatcg actttgacag atatgtcgat tgtcagtgca atcacttcaa
     5041 cagtttttat tatattatta gggtttgttt gtagaaaaaa ggggattttt tctgaatctg
     5101 ttggaaaaat tctatcgaaa gtcgtcttaa cagtggcttt gccagcactg gcatttcgag
     5161 ctttcatgca agatatcaat acagaattac tgatgcaagg aatcaatgtc ttgatttggg
     5221 gattagttat ttatattatt cttattctag tttcaaaacc ttttttctta agctataaag
     5281 gggataagca aacaacgttg cgtgtcctga cgatctttgg ttctacgacc tttttcggaa
     5341 cgcctatcgt cagtgcgatt tatggtcctg tcggcgtgat gtattcctca attttcaata
     5401 ttggctaccg aatctttttg tattcttatg gatacataaa aatgagtggc ttgaagatgg
     5461 aagctaaaaa tatcaaagcg atgttcgtca atccaatcat tatcgctact tttgccggcc
     5521 ttttcatttg gctgttccaa gggtatctgc cacaagtgtc agttacaggt gcagaaggag
     5581 agataagcca agtagcgttt ttgcgaattg accagactgc accgtggcta tttcagccga
     5641 tggattattt agctggttta agttcaccat tggcgtggct agcaatcggc gcaacattag
     5701 gtgaagtaag cttcaaaaaa gctgcatctg aaaaaacttc atggtattac agtctagtca
     5761 aagtggtatt tgtacctgca ttgaatatcg tgattctagc agttttgacg gcaacgaata
     5821 ttctaccagt caattttgaa gcactggcaa caatcgttat catgatggct acaccagctg
     5881 caacagtggc agcagcctat gctatcagtt ttgataggga ggcactttta gcctccaatg
     5941 catccttact gtcaactatt tttgctgtgg tactgacacc tgtatggatc gttgtattac
     6001 aaatgattca tggcataggt ttattttcat aagaaatgga ggaagaaagt atgagaatcg
     6061 catgttacgg tgttcgtccg aacgagatag atttttttga aaaattgaat atttaccatt
     6121 atgatctcag tctttatgaa gaactgttga cacatgacaa tatcgtgtca gcaaaggacc
     6181 atgatgctgt attgttgagg ggaaattgta tagcagatga gaccaatctt gcaaaaatgc
     6241 aggaatatgg gattcgttat gtttttacac ggactgtggg agtcaatcat atcgatctac
     6301 aagcggcagc tgattttggt atgacagtag cccgtgtacc atcgtattcg ccaaatgcga
     6361 tagcagagtt atctttgact tttgccatga tgcttttgag aaatactgcg tatacgacga
     6421 tccgaacatc tttcaaagat tttcgagtgg atgagcaaat gtttagtcgt gaaatcagaa
     6481 attgcacagt agggatcata ggaacaggca ggatagggtt gacggaagct gttttgttta
     6541 agggactagg agccaaagtg atcggctacg atattcatca gacagaagct gctaaaaaag
     6601 tattgacgtt ccactcgctt gaagagttat tagccaaaag cgatattgtc agtattcatg
     6661 tacctcatat cccaggtgaa aacgatcaaa tgatcaatga aggattttta gctcaaatga
     6721 aaaaaggtag catcttgatt aatacagccc gtggagagct tcaagataat gaagctattt
     6781 taagagcttt gaaaagcaat catttagctg gttttgcaac cgatgttttt gcaaatgaaa
     6841 cagaggtttt tttccgatcc ttcaagccat gggagacgat tccagaccct gctatccagc
     6901 aattagtaga aatgtaccct agagttcttg taaccccgca tgtaggttca aatacagatg
     6961 aggcattatc aaatatgatt tcgacaagtt tcgagaactt tcgtgaaata atagaaactg
     7021 gaaaaacgaa aaatgaggta tctcttccta aagcccgtca attaagataa gaaaacatgg
     7081 atattcgtca ataaaatgtt taaaaatagt ccaagtaaac agttgttatt tctgtatact
     7141 tggactattt tgtatgggat aattcgatga ctcaacagta atctgtgagc tttttccgcc
     7201 cattctttgt caattcataa caggttagcg gccggccgat ttccaaatat ttgattcttt
     7261 cgttcaatat atcttgttct actaaaaaat tcaaatattt cttgacggat atacgtgaca
     7321 gtgagctttt ttgagccagt tcttttgttg aaaaaatagt atcttctttt agaataaatg
     7381 cacttatttt ttttaaagtc agttttgaca gacctttagg caaatcgatg aatgatggta
     7441 tttcgtgaat gggagtggtg tggttgaata cttgatcgat caatttctga tcggcttttt
     7501 cagtcgtttg gattgtctga gagaaagcaa gatacttttc gatcgccagc tgaaaacgtt
     7561 gcaaagtgaa cggtttgatc aaataatcta aggcaccgta gcggatcaca ttctttatgg
     7621 tttcgatatc atctgcagca gtgatcaaaa tcactgggat atcatttcct tgctgtctaa
     7681 gccaagataa aaaatggata ccactttcgc caggcatgta tacatcaagc agcagcagat
     7741 ctgcgttttt ttgtctgaaa tatttttttc cttcttctac atttctgaaa ctttcgatta
     7801 cgttcatatt agggatgctt tccacaaaag tacgattcaa ttctgcaacc attggatcat
     7861 cttcgattat caggacattt gtcatcattt tgatcttcct tttttggtaa ttctagatag
     7921 acgattgtac cgccatttgt ttgtttggaa aattctaaaa atccaccgtg gcgtttgacg
     7981 attgaatgga tgagattcaa tccaaaccca cgattgattc ccttcgtcga aaaacctagc
     8041 gtaaatattt tttctgagat ttcttctgat atcccgacac cgtcatcgca gacggtcacg
     8101 atgaatactt cagcttctgt gtcatagttt aaatgaatcc ggacctgtcc gtttctttca
     8161 tgtttttgta gcacggcttc ttttgcatta tcaagtaagt tccctaacac ttgcaaaagt
     8221 gaatggatgg agtcatccat ctccatttta gggataaaag aatcgctttc taacagcatt
     8281 tcaacagatt gttctttggc ttcgtttatt ttgcctaata aaaaaccggc aattgcaggt
     8341 actttgatca gacttgagac ttggccaatc tcttttttat aattttgatt tagctgctgg
     8401 ataaaatggg tgacttcttc atacttcttc aaatcaatca aaccagaaat gacatgaagt
     8461 ttattcatga attcatgggt ttgagctctc atggagttta tatattgttt cgtcccccca
     8521 agctcctcca ttaatttcat tacttctgat cgatttcgta aagttgcgac tgctcctaaa
     8581 aaacggtcat tgctaaaaag aggtgtaacg ctagaaatag tttctatccc atttaaatac
     8641 atggattgag tccgaacggt cgtttgatgc tcaatcgtct ctttaaacaa aacgtcatat
     8701 agattatcac tgattttttt cctacttcga aatccaatag ctgctctgtt tggtagaaaa
     8761 tgttttttgc aggtgtattg atcaagagga tagttttatc agaagagatg gctaagattc
     8821 cttcatctac ttcattttcg ataatcgttt tttcacttaa ctgttctgct atttcttgtg
     8881 gttcaagtcc aagcagtact tttttcattt tttgggcaag aaaaacggcg cctatgatgc
     8941 ctacgctaag tccaataatc aatgaaaaaa caatcatttt ttgtccatct ttgacttgat
     9001 tgtcaatcgt gttgtttgtt aagccaacac aaactgcacc aataatctct tgatcataat
     9061 aaatagggac gaaatagcgg aagccgaacc ctaacattcc ttctttttca gagaaaaatt
     9121 cttgtcctcc aatcactttt ttcacatctt catgacttga gaaaggaaga ccgatgtaac
     9181 ttgggtctgc gtgagaatat cgaatgcctt cagggtccat gacaacgata aaatctaaat
     9241 tcgatgcaat catgatttca tttgttattc cttgaatcgc atgtgtcggg tcaccagtct
     9301 gcagcttttt ttggatgagt ttatcattgg caacgatttt agcaatgcta gagattttat
     9361 ctgacacact agatcggttc atcgaaagaa taaaattcct gatcaatatg gcagaaacaa
     9421 tcaaagaaac gaatgtggag aaacaaacga caaggatgat cgtgttctgg agctttaatg
     9481 gttttttctt aaaaaaagga aacataggct acctcgaaag aatttattgt gaaaatttta
     9541 acatgaaaac aaaaatttaa caaattgtca acgataaaca caaccttcct ataaaaaaca
     9601 ccactgagtc ggtaaaagaa gctatacaga attttcaaac attggtatga tagacgtaga
     9661 aatggaagga ggcgtgtata tgataggggg aatcgcactt gagacgattt attggtatac
     9721 attgctgatt tgtgcaggat tggcagtcct attgattatt tttggagatg tattcgattt
     9781 tgatggcccg cttgatccga tgcttattat cccttggtta actttcacaa gcttatttgg
     9841 ttttctaggt gagcgtttaa cagatcaatc atctttattt ttatttattg ctagtggagg
     9901 catatcgata gtgttggtat ttttgcttaa tttctatata ttgatgccga tgaaacatgc
     9961 cgaatcaacg atgtcgtctt ctgaaaaaac tctggaagga caagtagctg ttgtgatcac
    10021 accgatccct gtacgaggta tgggagaaat tcagttgaaa agtgttaccg gttccattag
    10081 tcgtccagct tgtttttaca gcccccaaga acagacagct gagcggggaa cgaaagtatt
    10141 gatcattgag atcaaggaaa gaatctgtta tgtcatgcct tatgaaagca tgataaaagc
    10201 ttaaaggagc gtgtgttaaa tggaaatacc agttgttttt atcgcgatcg caatcgcagc
    10261 tttgatttta ctgatgttgc tgatcgtctt tgtagcgaag taccagacag caaaaccgga
    10321 tgaagcgttg atcatcagtg gaagttattt aggaagcaaa aatgtgcaca ttgatgaaag
    10381 caataacaaa atcaaaattg tgcgtggagg tggcgcattc gtcttgccag tttttcaacg
    10441 ttcgaatcgg atcagtctat tatcgagtaa attggacgtc tccacccctg aagtgtatac
    10501 ggaacaaggc gtaccggtga tgtgtgatgg tacttcgatc atcaaaatcg gttcatctgt
    10561 agaagagatt gctacagcag cagaacagtt tttaggcaag acaagagaag aactggaaaa
    10621 tgaagcaaga gaagtattag aaggacactt gcgctcgatt cttggttcta tgactgtaga
    10681 agaaatctat caaaatcgcg ataagttcag tcaaagcgta caagaagtcg cttctgtaga
    10741 ccttgcaaaa atggggttga tcatcgtttc tttcactatc aaagaggtca gagacaaaaa
    10801 cggttatctt gactctttag ggaaaccaag aatcgcccaa gtcaaaagag atgcagatat
    10861 agcagaagcg gaagctctaa aagaaacgcg tatcaaaaaa gctcaagcag aaaaagaatc
    10921 acaagcagct gaattacagc gacaaacaga gatcgcagaa tcattaaaag aaaaagaact
    10981 gaaattagca acctacaaac aagaacaaga tgttgctaaa gcaaaagcag accaagccta
    11041 caatttagaa agtgcccgag cacaacaaca agtaatcgaa caggaaatgc agattaaaat
    11101 cgtagaacgt caaaaacaaa tcgaactgga agaaaaagaa atcacacgtc gtgaaaagca
    11161 atatgattcg gaagtgaaga aaaaagcaga tgccgatcgg tacgctaaag aacaagaagc
    11221 acaagctcaa aaagtcaaag aagtgactga agccgaagca gaacgattcc gtgtggaagc
    11281 actggcagaa gcggaagcca ataagacacg tttagctgga caagcagaag ccgaagcagc
    11341 actagcaaaa ggaaaagcag aagccgaagc aaaacaaaag atcgccaatg ccttcaagga
    11401 atatggcgaa gcagctgtct tgagtatggt tatcgatatg ctaccgcaat tgatgcgcga
    11461 agcagcacag ccgctaggaa atatcgaaaa aatctctgtt gtcgatacag gaagcagttc
    11521 aggagaaacc agtggagcga accgagtgac aaattatgcc acaaatttgc tttcttctac
    11581 tcaagaaaca ctaaaagcga caacaggact tgacttgaag gaaatcgtag agaatttgtc
    11641 gacacgtggg actactagcc aagtaaatat gtatgaagcg ccaaaagagg cagaacaaaa
    11701 ctcgatgaag gaagaataaa gtagtacact tcaccgttca atcaaaaatg gaggaagact
    11761 ttttaaagtt cttctctcca tttttttatt ttattgcaaa agaaaattag tcctcgctat
    11821 ttttcttttg tttttggatc ttagcttcta tctcttgtaa atttgttctt agcaatcgtt
    11881 ctttcttttg gagttcgacc aaatcttctg atagttcttc cttcttttct gtttcaggag
    11941 gacgaagaaa gaaattgata ccgattgcaa tgaatgtccc tataaaagta tctagtacac
    12001 gttggatagc atacaaagcg gattcgcctt gagggatgct caacgcaatc agcaacaacg
    12061 tagctattgc ggaaatgata ccggaattat tgttaatacc atctgacacg acgatcacaa
    12121 taataactag aataggaagc aagatcaatt ctaccaaaaa atcattgtga aaatagcttt
    12181 tgacaaaaaa ataaatgata gctaatgtac cacctaatgt attgccgatg atcctagact
    12241 ttccaaaaga aacggttgta gtcaagtcct gacgcaaaga aaaaacagca gataatgcag
    12301 caatcatcgg gattcctcgt tgagtcaaat gaaaaaacaa gatacataaa aaaacagcta
    12361 aggcactttt gatcgtacgc atacctagtc gaaaacggcc aaattgcata gagattctcc
    12421 tttttggtct ttttactatc atacctaaac ttttgtctga tagctagttt ttcattattc
    12481 aagtataatt aaaataaaaa agggggaagt aaatgcgtat aggaatgcga acagtcaaaa
    12541 cagtgatcag tgtcttcttt tcgatggtca cagcgggtag cttatcgctg ttgtattggc
    12601 cagctgcagg gatcattgca ttattaagtg taggaaatac caagcgctct acattgcgta
    12661 cgggcatgaa tcgaatcgca gcctttatat tagctacggc aacagcactg ttcagttttt
    12721 ttgctgttgg gtatactatt tttggcttca gtcttttttt attcctgttc atcccgcttg
    12781 cctctcgctt caaattaacc gaagggatag tagtaaattc ggttttggtc actcattatt
    12841 tagtggagga aaacatgtct tggcagctga tcggcaatga agcgggatta atggcgattg
    12901 gattagtatt tgctttgctt gcaaatgttt acatgccaga tcgtacgaag cagctgaagg
    12961 aaaaccaaat acagatcgaa aaagaatttc gaaatatttt gagacaaatg gcagaatttc
    13021 ttttatcaga aaataaagaa gatgtgcaga tcaaatgcga acatttactg acattcattc
    13081 gcgaaagcca agaagatgcc agagaacatc aagaaaacta ctggctcaga cagccgctat
    13141 actacgaaac ttacttctct atgagaagag cacaggccaa tgtgattaaa gacatgctgg
    13201 aaaatctaga gagaatccag caaccagctt attatggaaa acatatctat ggtttattga
    13261 tttatactgc agaaacattt tcagagtcaa atgatggcag acaaatttta acacgtattg
    13321 aagaagttta tgtattgtat cggcaaatgc ctctgccgac tagtcgccct gaattcgagg
    13381 atcgagcaga attgttccag tttttgcagt cttttaaaag ttttattgaa atcaaggcag
    13441 aattctccca acaaaaaatc caaaaataga ggttgtgaat tcagctaata ttcaggtcaa
    13501 aaagctgatt tcacaacctc ttctttaaac ggtgttctcc tgtcaactcc tcggtcacaa
    13561 gtcacaatat tcaacaaaca tgagaagctg ttttttgaaa ttgctccttg tgactcggag
    13621 ctgaacggta ggctcacaac ctctttctta aacggtgttc aaaagctttc ctctgcggta
    13681 ataagtccag ccaaacgaaa aataggagga gctatttttg tttggctgtt cttattactt
    13741 gatgcagaac agctttttca caacctttta aaattacata tttttccata gaacttgcat
    13801 ttgatccaag atttcgatga catcttttgt caagaagaga gagcgattgg gcaagtcacc
    13861 ttcaatcatg tgtaccatat tctttatttc gtaattcatt gcttcagatg tattcccgct
    13921 ttcgatgaat tcctttgtac catctgtaaa taagatctcc gcacgatcag cacgcgggta
    13981 atcagcaatc gtcacataac cgttctcaaa ggcaacgata ccgacttttg gcatttttgc
    14041 ctgaaaagtc aagctgacag cagcaagttc attttctttg ttacgcaaga tagtgacgga
    14101 ttgttcgtcc acgcctgttt caaaaggaac cattgtagag gcaactactt caggttgaga
    14161 gctcaaaaag aaacgagcga aagatacagc atacgtaccg atatccaaca gagctcctcc
    14221 agctaattct ggattgaaga accggttttt agggtctggt tctttgtaac tgccgaaagg
    14281 tgcttggatc atttttaaag cccccagttt tcctgtatcc attattgagc gtaactgctg
    14341 ataaagtggc atgttgaaga ttgtcatcgc ttctgctaag atcaaattct tttcttctgc
    14401 taagcgcata gcgtcagcca gttctttttt attcatcgtg atggcttttt cacatagaac
    14461 gtgtttgcct gcttccaatg ctgccaagat atggtcgata tgctgtctat ttggtacagc
    14521 aatgtacacg atgtcgattt cagcatcgtc taacatttct tgatagcttc cgtaagcttt
    14581 tggaatattg taacggtgag cgaagttttc cgctttttct gaagttctgg aagcaactgc
    14641 tgttagttcg ctcgtctctt gattgaagct ttcggcaaac tcatgtgcga tggtaccaag
    14701 accaacgatt ccccattgat attttttcat ctgaaaacgc tccttcatag ttggattgag
    14761 tttcttgtct gtctattatt ataacaaaaa tcacgaagaa taaagaggag aggacttgaa
    14821 acattaaaaa aaatgaaagc agcgatttaa gaggtgcttt ttgatcaaaa cttaagtaga
    14881 atagttaaaa ggaggggata aacgtgcatc aagtatatat tgatcttatt atgagtgtat
    14941 tattagaaca gtttgaaact gaaaaaaatt ttttagatga atacttgctg atcagtccag
    15001 aacaatggca aaaatggaaa gatggcgaga aaaatctgcc atctgaagcg atgcagaaag
    15061 taaaaaatct tttcactgat tatgaatgga tgctaacgca aaagattttg cgtcaaacga
    15121 ttatttttcc cgaaaaacga aacgttgccg ttgcagagta caagcaaatc aaaacacgca
    15181 tcgcgcaaaa atggcttagc agcaaagcag caaaagtcga gctgatccct ttgaaaaata
    15241 atcagcaggc tggtagatac cttgacttga aagtaagtat tcaatatgat gaatggggct
    15301 atgatgatat tttgaatttt cgtctgccag cagatgttca aaaacagatc gaaggagaaa
    15361 aaatcgaact tctcgattgg gtgaatgaaa atctggaaga aacttacgtt catgaggcga
    15421 atggggaacg tgaagaacaa cgaaaggatt tttcaagtga ataaattttt aggatttgga
    15481 gcagttgtga ttatgatcgc agcaatgggc tatgttattt ttagcgatga tgattcgcat
    15541 gttcaagccg gcaatcaagc agtcgaacga acaagcacca aaacaactgc tagtaaagaa
    15601 aagaacagtc aaacaaccag cagcaaggta aaggacaaag aaacaaaaga tcgtacgtcc
    15661 aaacaattgc cagatgttaa aacagacgat tggaagctag ttttggttgg tccagatcac
    15721 aaattagaaa aagaaattga tgagtctact caattggcat cattaagtaa cggatacttg
    15781 atcgacaaac gcattgctcc agaatatgaa gcatttgcca aggctgctga agcagctgga
    15841 tttccattag tgatggtctc agcttaccgg tctgtatcat cccaacaaca agttttcgaa
    15901 caaaatgtcc aagatgtgat gagtcgtcaa ggtgtatcag aagaggaggc gacaaagatt
    15961 actaaagaaa cgattacgga gccaggatac agcgaacacc acacaggtct ggcagtcgat
    16021 gtcgtcgatc aaaactggta caacagttat ccttctactg tattggatgc aagttacgga
    16081 gatcagcctg gagctaaatg gatcgcagat aatgctgcgc agtatggatt tatcgttcgt
    16141 tatccaaaag gacacgaaga tataactaag atcacatatg aaccttggca cttacgttat
    16201 gtcggtaaag aaaacgctga gtatatcacc aaacaccaat tgacgctaga agaatatctg
    16261 aatgaattaa atgaaaagta ggaattgatc atggcgaaaa aaaagtggaa aaagcaaaag
    16321 cgcaagaata tccgttggcc agcagtggtt gccggtgtag cagtgatact cttagccttt
    16381 gttttttcct tgaagaatct gtcttctcct tttactgata atcagcaaga aaatgaagcg
    16441 caatcccatc agcaatttat tgaacggctt gttccgcatg cccaagaact acaagatggt
    16501 tatggagtgc ttcctagtat cattttagga caagctatat tagaatcaaa ttggggaaaa
    16561 agtaccttgg ctagcaaata caataatctt ttcgggatca aggcttatgg ggatcagaag
    16621 aaagtaagcc tggaaacaaa ggaatttgtt aacgaagaat ggataactat ccaaggagac
    16681 ttcaaagtgt atgattcatg ggaacagtcc atggatgacc atacacaact gttcgtccaa
    16741 ggagtagatt ggaatcctgc gctgtatgaa aaagtgatta cggccaccaa ctatcaggaa
    16801 gccgcacaag cattgcaaga tgcaggttat gcgacagacc ccggttatgc gcaaaaaatc
    16861 atccaggtca tcgagacgta tcaattgaat cagtatgacc ggagatagca aaggagaagt
    16921 ggctgatggc agaacaattt acgccagaaa tcatgacgga attgagaaaa gatatcgtaa
    16981 gagtaccgga aatcatttta gaagcaagcg ggatcaagat atttggaaaa ttgatccgtt
    17041 cgatcatctt tactacggat attgcgatca tacgtaatac aaatgcgaat gcagtaattg
    17101 ctgtgtatcc ttttacacct catccagcga ttactaaaag cattattgag gcagctgaca
    17161 ttccagtttt ctccggtgta ggtggtggtt tgacacaagg tgctcgttct tcctacatga
    17221 gcatgttcgc agaagcgcaa ggttcgttag gggtcgtttt gaacggtcct acgcctttag
    17281 agacagtaaa agaagtttgt cgagtagttg atattccagt tatcagtacg gtaacgtcga
    17341 aatatacaga aatagatgaa aagttagcag ctggtatttc gattatcaat atcagtgcag
    17401 gtaaagaaac tgcagaagca gtacgccatt ttcgtaaaaa atatcctgaa cttcctatca
    17461 ttgcgacagg tggtccaacg gaagaaagta ttgctgagac cattcaagca ggagcaaatg
    17521 ccatcacata tacgccacca agtagcggag agctttttag tcgtaaaatg gaaaaatatc
    17581 gggaaactga gaaaaagaat catgaataac aggtgagaat caaaagacga ggaagagcag
    17641 atagtggctc ttcctcgtct tttgtactcc agtactattt gttcagaatt caaaaaaaag
    17701 agaaattttt ttgttttttt acctgtaatg tacataagaa gagttaaaac cttttgttat
    17761 tattagcatt ctaacaaaaa aatgtcttga tttattgaag cgctttctat agaatgaaaa
    17821 acgaataaaa actaaaaaag gcacccgaca atttagtagc agctaaattg tcggggcttg
    17881 aaaagtcagc gggaactgac caatcaagtt gccatagtca atgcttgtgc atcgacgtgt
    17941 atattgtacc taatttcata cagaattact agttattttt ctgtttttta gggaagagcg
    18001 cacacgaaga agcatgctta tttagctatg tcaaggatat tgggcagttg tctgatatcc
    18061 ttttttcttt gcgtaattat cctcccatca ttgaagcaag aagtgttttt agcgatgaaa
    18121 gaagaatcag cactatctaa tttttcttga aagtattgag ttgttcatcc taggcagaac
    18181 gataaggcaa gtcttggttt ttattcccct tgaaaaagat cgtttaataa atatgttctg
    18241 tataaaaata cagtatattg aaaaataaca atggaagtag aggtgcagag aatgaagaaa
    18301 agaatgagaa tcatcttagc tttaagtgtt atgttattct tcttgacggc ttgtgggcaa
    18361 gaagatgaca aaaaaatcac gctgaacatg gcttggtggg gttcgcaagt ccgacacgat
    18421 gcaacagtaa aagtaatcga gctttatgaa gaaaaaaatc cccatgtgac gatcgattat
    18481 gaattttatg attatgaagg atattacaca aaattaggta cactagcagc atcagatgat
    18541 atctgggaca ttttccaact gaacaatcaa tttcctcaat acatcaatca gattgaacca
    18601 ttagatgaat atgtggagca agggataatt gatatttcta atgcagatga atcctattta
    18661 gcaacgacga cttacgacgg gcaattagtt ggactgtcta acggggtgaa ttcgtttgcg
    18721 attgcttaca ataaaaatat atttgaacaa ttaaatatcc ctgaaccagc ttcaaattgg
    18781 acatgggatg aatttgaaca aatcagctat caaatcactg aagaattagg aatctatgct
    18841 atttcaagat tcgaagattt tatagctggc tgtattattc aaataccaca agttgagaaa
    18901 ggattgaatt tttataatcg ggaagatcta tctaacagct tgggatttga aaatccagac
    18961 tatctaacag attttttcca gctgcgtaaa aatctggtag acaaaggggc ccatccagaa
    19021 ccaggtggtg gagctgcaag tacgacggat ctgtcttttc aggcggttag ggatagagaa
    19081 gcggcaatgg tgtttctatc aagtaaccag ttgacagaaa tattgtcagg ggctcctgaa
    19141 gatatggaga ttcagttgat taatccacct cgcagaaaag cagatggaga atctggtatc
    19201 cctttacgtt cttcgcaaat gctgagtatg gcaaaaagct cagcccataa agaagaagct
    19261 gctaagttta ttgatttctt tcaaaacagt gaagaagcca atgaaatttt aaaaggagaa
    19321 cgtggtgtac caatcatgtc gaatattcga gaacagctcg ctcgtgcaga tgatgcaact
    19381 ttgcaagcga catttgatta tttagaaatg atttccgata tggacaacgg cgaagtgaat
    19441 gtctttgata gtgctttgaa tccggaaatt caagaccaat acaatctttt agttgaaaaa
    19501 gtcatttatg aagaagtaac agcagaagaa gcagcagaga gtctttatga gtttgcgtca
    19561 aacattctag gatagcagca ggaggaaggc atgaaaaaag aaaaactaaa acggttcttg
    19621 gatcaagaca atgtggtcgg ttacgtattt gcttctccat tcatcctagg atttctattg
    19681 ataacagtga taccgatgat cttgtcactt tattattcgt tcaccgatta tcgtttggga
    19741 aatccagtct catggatcgg cttggataat tatataaaga tgctgagtga tgcccgtttt
    19801 ttgaactcca tccgagtcac ttttctctat gtatttgcat ctgtacctgt gaaactgatc
    19861 tttggtctat tgattgctta tcttttaacg aggaatatca aaggaacgac tttctttcgt
    19921 tctttgtatt atgtgcctag tttgatcggt ggcagtattt ctatcgctct agtttggcgg
    19981 gagttgtttt ctaaaaacgg gttagtgaat attttcctgg aacgattagg cgcacctgcg
    20041 ctttcctggt ttagcgatca aaaactggtc atgatccctc ttgttttgat gtctgcttgg
    20101 caattcggtt cggcaatgat catctttgct gcaggtatca aagagatccc aggctcgtat
    20161 tatgaagcgg cagagatcga tggagcgaac aaatggcaga cgttttacaa gatcacgtta
    20221 cctcttcttt cgccgatcat tttgtataac ttggttatgc agacaatcgc ggcgtttatg
    20281 acttttacgc aggcatttat cattacccaa ggtggtccga atgatgccac gaacttttat
    20341 gctctttatg tgtataacca agctttttct tttaattcta tggggtatgc tagtgctatt
    20401 tcgtggatca tgctgttgat tatgggagct gtcacctttc tgattttcaa atcatcaaaa
    20461 aaatgggtcg ttgtgtgaat gagaggagga agaaatgaat aatacagtaa cgaaatggtt
    20521 tcaatacggt tttattttgc tattaggtct agtcatgatt tatccggtct tatggatgat
    20581 cgcaggttct tttaaaacgg atcaagagat tatgagtggt tcgctgaatt tgattccaga
    20641 gacttttcaa tgggaaaatt acgcaaaagg atgggcgggg tttgctggaa tttcattttt
    20701 tactttcttt aggaattcgt ttgtcatctc tgcagtttcg acgataggga cagttctgag
    20761 ctcgacttgt attgcttacg cattatcgag aatcgatttc aaaggaaaaa gattctggtt
    20821 cgtcgtcatg ttagtaacga tgatgattcc tgcacaagtg attttgattc cgcagtttat
    20881 tatttacaat cggctgaatt tggttgggac gtatgtgccg ctgattttac cacatttttt
    20941 tggacaagca tttttcattt accagatcat gcaattcatg gtcagcatcc ccaaagagtt
    21001 agatgaatca gcgattattg acggatgcag caagtatagt gtctttacca aaattatttt
    21061 tcctttgctg aaaccttcga tcatcacgac gatcatcatc cagttttatt ggaaatggga
    21121 cgacttcatg ggaccattga tttatttaaa caagccgaga tcttacacgg tatcgattgc
    21181 catcaaatta tttgcagacg ctggatctag tacgacttac gcgagtatgt ttgcgatgtc
    21241 tacgttgtcg ctgctaccgg tttttctgat tttcttattc ttcaataaat atcttgtcca
    21301 ggggatcagt acaagcggtc tgaagggctg aatatgaaaa agccaataga agagatgttt
    21361 ctttacaagc tcaactacta tgtctgtcgg atttttttaa ccagtcttat cagtaatgct
    21421 cttttcgctt tagttctagg atgtttgttc actttaggat tagtgctgtc tgctcgtgtt
    21481 gtctatctga tttatttttt gatgatgtat ccttcttatt atctatctgt ccattacttg
    21541 gcagaaaaaa aggtatgttg gaggaaagga aaaatcaaac ggatgtgttt catcattacg
    21601 ttgtttcagc tgtttgtcat tatttttgca gttgattggt atttattagt gggaaagatt
    21661 ggagcttggt atctgattcc ttttctattg tgtctgttgc tttttgtatc ccatagtttt
    21721 tttagtacgc taattgatat ctgcaaagaa gataaagcag atagtcttgt ttatttgatc
    21781 aaaaggaata tctggctgtt gtcaaaaaac gtcaaggggt ttctgtggta tttatgcctt
    21841 ttgtatggac tgttctggtg tatacagcat gattttttac tcactgcatt actgtatcca
    21901 gggctgccat ttgtcacagt attttgctta aaagaaaagg agaatgactt taaatgaaga
    21961 aaaaatatgt acaagtcgga cttggtggga gagcgcgttt tttttatgag gcaattgcct
    22021 ctacgtatca tcaaacttgt gaactagtcg gtttttgtga tgtatctcaa acaaggatgg
    22081 attatgcaaa tcggatactt gtgaacaagt atggacagaa aaaagtaaag acatgtatgc
    22141 catcacaatt tgagcaacta ctggatgacg tacggccggc tgaagtcatt attacgtcag
    22201 tagatcgaac gcatcatgat tatatcattc gtgcaatgaa aaaaggatat gatgttattt
    22261 gcgaaaaacc tctgactatc gatgaggaaa aagctcaaga aataataacg gtccaaaaac
    22321 agacgggaag aagcctgcga gtcactttta attatcgtta tgcaccgtat cacacgaaga
    22381 taaaggaact gatagaaagt gatgtgattg gtgatgtgtt ttctatccac ttcgaatggc
    22441 tgttaaatac gcaacacggg gcagattatt tcagaagatg gcatcgaaat aagcacaata
    22501 gcggcgggct tcttgttcat aaatctaccc atcattttga tctagtgaat ttttggttga
    22561 acagccgtcc ccaaaaggta tttgcattcg gtggattaaa cttttatggg atgcataatg
    22621 cggagaaacg cggagtagaa atattttaca gtcgatgcta tggaagcgaa ctagctaaag
    22681 ctgatccatt tgctatagac ctgtcagcca atgaggaatt gcgagaaatg tatttagaag
    22741 cagaaaaaga cagtggatat attcgtgacc gcagtgtatt ttccgatgat atctctattg
    22801 aagatacact aggcgtaacg gtcaaatatg aaactggtgc gattttgacg tattcgctaa
    22861 acgcgtatat gccgtgggaa ggattcaatg tttctttcaa tggcagcaaa ggacggatcg
    22921 aaatgaaagt gatcgaaaag tcttacatca atgcaggtgg agataaaaag gatgaaggag
    22981 cagccgttct tcagtccatc catgtctatc cgatgttcgg tgagccatat gaggtaatcg
    23041 tcgaacaaga agcgggcgga catggcggag gagatccgcg tttattagat gatctatttg
    23101 gtgaagaaaa agaagaagat ccgtggaatc gggcagcaac tcacgtagat ggtattttgt
    23161 cgattttgac aggaatcgca gcaaatcatt ctattgcttc aggaaaagca gtagtgattg
    23221 acgagcttgt cagcttaaaa gaataagaat agatttacgg aaattacttc ccgtagttta
    23281 taaaatcttg ccttattgcc gataggctgt cttttgaaca ctatttattc ggaaaaaggg
    23341 gctatgacat gctttttgtc atgccttctt tttatgtggg ctgctttttt agataggaga
    23401 aaataaaaat aactatttaa acccgaacaa aaaggaataa tgcattaaaa atcattagat
    23461 tttacaaaaa aataagtaaa ccacgttgtc agtttcagaa agtagtgtta gactgttttc
    23521 aatatttgaa acaacatttt ttattcaaat atggcaaact gccttcacgt gcaaaacagt
    23581 tgcaagaaaa tgaatttaca ctattattag ttttacatac ctacttatat atcgtcataa
    23641 tatggatgac agtttctagc cagtaccgta aatgctggac tataagtaaa agattggcta
    23701 tttcaccctt cttttcttat gataaagtgg agggtgtttt tctttaacag aaacatagta
    23761 ggtttttgca caaaagcggt tatttcggta ttaataaatg ataaaggagc aaataaagtg
    23821 aaagaattag ttgaacgtat tcaaaaagac ggacgtatat taggcgaggg cgtattaaaa
    23881 gtcgacagct tcgtcactca ccaagtagac cctgtattga tggaacaaat gggaaaacgg
    23941 tttgcagaag tatttaaaga acaaggaatc acgaaagttg tgaccattga agcttctggg
    24001 atcgcaccag ctttatttgc tgcaagagaa ttagatgttc caatgatctt cgctagaaaa
    24061 gcaaaaagtt tgacgatgga tgaagaatta ttgacagctt ctgtttattc ttttacgaaa
    24121 caagtgacaa gtacgatttc tatttctcgt aaatttttat cttcagaaga caaagtattg
    24181 attatcgacg atttcttggc aaacggacaa gcggcaaaag gattgatcga attatgccag
    24241 caagctggag cgcaagtaga aggaatcggg atcgtcatcg aaaagtcttt ccaagatgga
    24301 cgtcagttac ttgaagaaat gggattgaga gtcgtttctc ttgcgcgtat tgcttccttg
    24361 acgaatggac aagttgagtt tcttgaggag gacgcataat cgtggaaaaa gaaacacaaa
    24421 atggaaaagc tgcggtttta gggctgcagc atctgctagc gatgtatgca ggagcagtag
    24481 cggtgcctct tttgatcggt acaggactag gctttaatca agaacagatg acttatttga
    24541 tttcaattga tatctttatg tgtggattag cgacattatt gcaattgaca gttaaccgat
    24601 ttttcggaat tggcttgcct gtcgttttag gatgtgcgat ccaagcagta gctccactga
    24661 tcttgatcgg aaccaatgaa ggagtaggag ctatctacgg atctattatc gcttctggga
    24721 tctttgttgt gttagtttct ggtgtctttt ctaaaattaa aaaactattc cctcctatag
    24781 taacaggaac ggttatcacc gttattggtt tgactttgat tcctgtagca atcgagaaaa
    24841 tgggtggagg taatgcaaca gcagctgatt ttggtgacaa aacaaatctg ctacttgcat
    24901 ttgtgacgat tctcctaatt gtaggcgtgc aaatgctggc aaaagggttc attcgttcaa
    24961 tcgcggtatt gattggttta gtcggaggaa gcatcttagc tgctttcatg ggaatgattg
    25021 atctgagcgc gattggagat gcgccgttgt tccatgttcc acaacccttt tattttggta
    25081 aaccaacttt cgacgtatgg tcgattttac taatgatcat catttccatg gtcagcatgg
    25141 tagaatcaac aggtgtatat tttgcacttg gtgacattac tgggaaaaat gttggagaag
    25201 aagaattgaa aaagggatat cgtgcagaag gacttgccgt tatcttaggc ggtattttca
    25261 atacattccc ttatactggc ttttctcaaa atgtcggatt ggttcaactt tcgggaatca
    25321 aaacaagaaa acccatctat ttctctgcat tcttcttgat tgttttagga ttattcccta
    25381 aaatcggtgc gttagcacaa atcatccctg agccggtact tggtggagga atgttagtca
    25441 tgttcgggat ggtggcagtc caaggaatcc gtatgctgtt ggaagttgat ttcagcaatg
    25501 ataaaaatct attgattgtt gctgtttctg ttggatttgg gctgggtttc aatgttacgc
    25561 cgacattatt cagtcaaatg ccgcaaacat tgcaaatgtt cactggaaat ggcatcgtaa
    25621 tgagtagcat tacggctatc atattgaatt tgatctttaa tggattgaaa aaagatgaag
    25681 aaatattgga agaagccttc aagaagtaat agagcaaaag aaaggttgtg aaatcagcgt
    25741 tttgacctga ttgttagaga aacaaacgga aaaatagttc ctcgtatttt gccgtttgtt
    25801 tgagctaata ccgagggtca gctgattgaa caccgttgaa ggaagaggtc gtgagcctgc
    25861 cgttcatctc cgagtcacaa ggaacaattt caaaaaaaag cttctcatgt ttgttgaata
    25921 ttgttccttg tgaccgagga gttggcagga gaacaccgtt tatccataaa aaggaatgtg
    25981 acctaacttt tgtcacattc ctttttttta tctttaataa acacgaacaa taaaatgttt
    26041 ttctttgtta acattcgaaa tttctttgac atcaaaaaaa gtgattgtta aaatatgaat
    26101 gtagaaaaac tgggaggaaa aacaatgaca gcaaaaatct ctgtgattat ggggagtact
    26161 tcagattggg aaacaatgaa agaagcatgt caaatattgg atgaattcgg tgtgtcttat
    26221 gaaaaaaagg tcgtttctgc tcatcgaacc ccagatttga tgtttgaata tgcacaaaac
    26281 gctcgaaaaa aaggaatcaa aatcattatt gcaggagcag ggggagccgc gcatctgccg
    26341 ggtatggtcg catcaaaaac aactttgccg gttatcggtg taccggtcca atcacgaaca
    26401 ttaaatggtt tggattcgct tctttcgatt gtccaaatgc ctggaggagt acctgtagct
    26461 actacagcaa tcggaaaagc gggagcaatt aatgctggac tacttgcgat acagatgctt
    26521 tccatgtatg atttagaatt ggaggctaaa ttggctgaaa gacgttcaat gttggctaaa
    26581 actgttatag aaagtagtga tcaacttggt taaacctttg ttgcctggtt caacgatcgg
    26641 gatcgtcggt ggcggtcaat taggtcgtat gatggcgatt agtgcaaaag aaatgggctt
    26701 taaagtaggt gtgctggatc ctgtgagcga ttgtccagcc gcacaagttg cagattggca
    26761 cattgaaagt gtctatgatg acacctttgc gctgaaagag cttgccagaa gaacagatgt
    26821 cattacctat gaattcgaaa acgtcagtgt agaggcgtta aatgcgattt tacccatgtc
    26881 atttattcct caagggacag acttgcttgc gattacgcaa gaccgcctgt tagaaaaatc
    26941 ttttttggaa acgaataaca tcgtgattgc tccttatgca acgatcgtca gtccgacgga
    27001 tatccaagat gcgattgacg ggatcggcta tccttgtgtt ttgaaaacca ctcgaggcgg
    27061 ctatgatggc aaggggcagt atgttttgaa aagtcgggcg gatctagctc ctgccatgga
    27121 ccttttaaga gaaggaacct gtgttttaga agcatggatc ccgtttgaaa aagagatttc
    27181 gatcatggtg gcaggaaatg gtcaaggaga tttcacgact tttccggtcg tggaaaacat
    27241 ccaccacaac aatattcttc atgaaacgat tgctccagcc gcgattgatc aggatgtgat
    27301 cgaggaggct gagcgtattg cccgtgtgat tgcagaagca gtgagccttt caggtgtttt
    27361 aggggtagaa atgtttttaa caaaaacagg cgggctatat gtgaatgaat tagctcctcg
    27421 tcctcacaat tctggacatt attctattga agcttgttct atgagtcagt tcgatgccca
    27481 tattcgaggt atttgtggtt ggccattagg agaaaaagta cgtttgataa gcaatgcagt
    27541 aatggtcaat gttttgggag aacaactgct ggaaagctat cgcttgattg agaataagcc
    27601 agactggcaa ttccatttct atggaaaaaa acaagcaaaa aaaggtcgca agatgggaca
    27661 tatcactatc ttgacagaag acatccagca aacgctggaa gaaatcaaac aaacgaatat
    27721 ttgggattag aggagaaaaa acatgttaga acgttataca cgccctgaaa tggggaatat
    27781 ctggacggaa gagaacaaat accgtgcgtg gctcgaagtc gagattttag cagatgaagc
    27841 ttgggcagaa cttggtgaaa tcccgcaaga agatgtgaaa aaaattcgtg agcatgcatc
    27901 atttgatatc gatcggatct tggaaatcga aaaattaaca cgccatgatg tcgttgcgtt
    27961 tacacgagcg gtttctgaaa cattgggaga agaaagaaaa tgggtccatt atggtctaac
    28021 aagtacggat gtcgtagata ctgcttatgg ctatctcatc aagcaagcaa atgatatttt
    28081 acgggaagac ttgaaacgtt ttacggaaat cattggcgaa aaagcaaaag aacacaaata
    28141 tacagtgatg atgggtcgga cacacggtgt ccatgctgaa ccaactactt ttggattgaa
    28201 acttgccaca tggtattcag aaatgaaacg gaacatcgaa cgatttgaac atgcggcaaa
    28261 aggagtagaa gcaggaaaaa tctcaggagc agtgggaacg ttcgcaaata tcccgccatt
    28321 tattgaagag tatgtatgta aacaattggg gatccgtcca caagaaattt ctactcaagt
    28381 tctccctcgg gatctacatg ctgaatattt ctcagcgatg gcgcttattg ctacaagtat
    28441 tgaacgtttt gcaacagaga tacgcggatt gcaaaaatcc gaaacacgtg aagtagaaga
    28501 attttttgcg aaaggtcaaa aaggttcttc tgctatgccg cacaaaagga atccgatcgg
    28561 ttcagaaaat atggctggtc tagccagagt ggtgcgcgga cacatggtca ctgcctatga
    28621 aaatgtcaca ttatggcatg aaagagatat ttctcattct tcagcagaac gaatcatctt
    28681 gcctgatacc acgattttat tgaattacat gttaaatcgt tttggcaata tcgttaaaaa
    28741 tctaacggtc tttcctgaaa acatgaagcg gaatatgtct gcaacatttg gtttgattta
    28801 tagccagcgc gttatgctga aattgatcga taagggaatg acaagagaag aagcttatga
    28861 tcttgttcag ccaaaaactg cgtacgcttg ggacaaccaa gtgcagttcc gcccgctgtt
    28921 agaagaagat ccaaccatca catcggtatt atctaaagaa gaaatagacg atgcctttga
    28981 ttatcatcat catttgaaaa acgttgacgt gatattcaaa cgagtaggtt tggaataaag
    29041 aagagtgagt tgcaaaattc aattaaaata gaatagcaaa aataaccaaa aaagaagcag
    29101 atccgttagc ggttctgctt cttttagttt attatatttt cttatcaata ataggaacct
    29161 gattttaaaa gcggctacct ctttaccgtg cctctttaca tacaaaaaat agaggaatta
    29221 agcgtaaatg gcttggctat tataactaaa atgctggtta tggagatgtt gcagcaagtt
    29281 ttcgagaaaa gcgtattcca tctcttgtcc attgaataag atctggatac gataatgatt
    29341 tttgaaacgc ttctgttcat gaatctgact gattgaaagt tcgcctttgt gttctgtctg
    29401 ataaagaaaa gtccttttac ggcattcagc acagcgcttg gttgctcggc ggatttttcg
    29461 gaatgtataa aaactagtat ctttattgca taaataaacg tctttgatcg acagcaaatc
    29521 attatataga caggaacgtt cttcagctgt taattctgat aaaaaaagct gaccttgttt
    29581 tattgcatct tccatcggca agtgcctcct cgaacccatt atccaaattt ttagttaatt
    29641 ctaatatacc atcattaagt ataaatgtaa acgcttgttg atggtataag attttcgttt
    29701 ctgataaaac acgaacatta aaagaatcta atgccttaaa tgtacatatt tttgttgatt
    29761 tataaaaaga tgattgctaa aatttaaagt gaaaaaacga acaaaaaacg atgtatttgc
    29821 ttttaatgta aataaaaagg agagacgtac atggagaaga aagaactttt gtatgaagga
    29881 aaagccaaaa aaatatatct tacttctgat gagaacttga tttggataga atatttagat
    29941 caagcaactg cgttgaatgg cgcgaggaaa gaccagataa gtggaaaagg agaattgaat
    30001 aatcaaatca caagtgcaat tttccgttat ctgactcaaa gaggaataaa aaatcatttt
    30061 attgaacaat tgtctaaaac cgaacaatta gcaaaaaaag tacaaattat ccctctggaa
    30121 gtggttatcc gaaatattgc agcaggaagt ttctcaaaac gtctaggtgt tcccgaaggt
    30181 aaagaattca tcaaaccaat cattgaattc tactataagg atgaccagtt ggatgatcca
    30241 tttatcaatg aagagcatat ctatttctta caacttgcaa agccggaaga aatcagtgag
    30301 ctgaaagccc aagcgttggc tattaatgaa attttgaccg aattatttgc taaggtcggt
    30361 ttggttttag tagatttcaa gctagaattt ggccggtcga atggacaaat tttgcttgcg
    30421 gatgaagtaa caccggatac ttgccgatta tgggatgaac gtacgaatga acatatggac
    30481 aaagacgttt accgcagaga tctaggtgat ttgatcccag tctatcaaga agtatataac
    30541 cgtctatcgg aactaactga agaaaaggag cgagtatgat gtatttcgta aaagtatatg
    30601 taacctataa agattcagtg ttagatcctc aaggggaggc agtaaaaaaa gcagtccatc
    30661 gtatgggata tgaaacaatc gaagatatcc gaataggaaa atactttgag atacaacttg
    30721 ctgatgcaga agaaccaatc gatacagtga ttgaaacgat ttgtgacaag ctgcttgcaa
    30781 atgtaaatat ggaaacatac cgatatgaaa tcaaaaaaat ggaggaagta taacatgaaa
    30841 tttgcggtca tcgtttttcc aggttcaaat tgtgacgcag atatgttatg ggcagttcgc
    30901 gagatcatgg gcgctgatgc cgaatttgta cggcatgatg agtcctcttt agaaggattt
    30961 gatggggttt tactgccggg aggattctcc tatggtgact atttgagatg cggtgcgatt
    31021 gctcggtttt ctacaatcat ggaagaagtg attcgttttg ctgaagaagg gaaaccagta
    31081 ttcggtacat gcaatggatt ccagatattg acagaagcag gacttttgcc aggtgtactg
    31141 agacgaaatg agtctttgca ttttatttgc aaaactgtac cattgaaagt caaccccaag
    31201 acggccttta cttcagagta tgaagccgac gaaataatct atcttccagt tgctcatggg
    31261 gaaggaaatt atttctgtga cgaagaaaca cttcaagaac taaaaaaaaa taatcagatt
    31321 gcctttactt ataatgacaa catcaacggc agcgtggaaa acattgcagg gattacgaac
    31381 aaagcaggga atgtgttagg aatgatgcct catccagaac gtgcagtaga agacttgcta
    31441 ggatcagaag atgggaaacg gttctttgct tccattttaa aaaacttcgg aaaggtgacc
    31501 gtatagatga aaacattgaa agaaccgaca gctgaagaga tcaagaaaaa aagaatctat
    31561 gccgaatggg gattgactga tgaagaatat cgaatgatcg aagaagatat cttaggaaga
    31621 atgcctaatt atacggaaac tggactgttt tctgttatgt ggagcgaaca ttgttcctat
    31681 aaaaattcta aaccggttct acgcaaattt cctactagtg gacctcatgt gttgcaaggc
    31741 cctggagaag gcgcaggcat cgtcgacatc ggtgatggac tagcagttgt cttcaaagca
    31801 gaaagtcaca atcatccttc agccgtggag ccttatgaag gagctgcgac aggagttggc
    31861 ggaatcatca gagatatttt cagcatgggg gctcgtccaa ttgcgttgct agattcattg
    31921 aggttcggcg aattagataa tccaagaacg aaatatttac tagaagaagt agttgcaggt
    31981 atcggcggat acggcaattg tatcggcata ccgactgtag gcggcgaaat tgcatttgat
    32041 ccttgttatg aaggaaaccc attagtcaat gcaatgtgcg taggtttgat tgaacacaaa
    32101 catatccaga aagggcaagc cgctggcgtc ggtaattcga tcatgtatgt aggtgcaaaa
    32161 acaggtcgcg acggtatcca cggagcaact tttgcctcag aagaatttaa tcaagaagaa
    32221 gaacagcaac gttctgctgt acaagtaggc gatcctttta tggaaaagct gctgcttgaa
    32281 gcgtgtttgg aattaatctt gcatcattcg gattctctaa taggtataca ggatatggga
    32341 gcagcaggac ttgtttcatc tagtgcggaa atggcttcaa aagctggctc aggacttata
    32401 ttgacattag atgaagtccc acaaagagaa actgggatga caccttatga aatgatgtta
    32461 tcggaatcac aagaacggat gttgatttgt gttaaatcag gagaggaaga aaaaatccaa
    32521 gaactatttc agaagtatga tctagatgca gtcactatcg gtaaagtaac agacgacggg
    32581 caatatcggc tatatcatca aggagaagaa gtagcaaatc tgccagtcga tgcattagct
    32641 gaagatgcac cagtttatca taaagaaatg aaagaaccag ctcgaatcgt agaatttcag
    32701 cagttagctc cttatcagcc agttatcgaa gaacctggac aagtattgct tgatctgctg
    32761 cagcaaccga cgattgcttc aaaacgttca atctacgaaa cttatgattc acaagtacaa
    32821 accaatacag ttgtccgtcc aggaagcgat gctgctgtga tgagggttag agggacgaat
    32881 aaagcgttag ctatgaccac agactgcaac gcgcgctatc tgtatttgga tccaaaaatc
    32941 ggaggacaaa tagcagtggc agaagctgct agaaatatta ttgctagcgg tggtaagccc
    33001 ttggcgatca ccgactgcct gaactatggt tctcctgata aaccagaagt tttttgggaa
    33061 ttatcgactt cagctgacgg aattgctgct gcgtgtgaaa cgttaggaac tcctgttatt
    33121 tcaggaaatg tctctttata taatgaaacg gatggtcaag caatctatcc aacaccaatg
    33181 attggtatgg tcggattgat tgaggatcat aaacatatca ctactcagga attcaaaaaa
    33241 tcaggggatc taatctatat attaggtaag acgtttgcag attttgatgg cagtgaatta
    33301 caaaagatgc agcttggaag aatcgaaggt gtgatccgaa actttgatct atccattgaa
    33361 aagagaaacc aagagttagt attgacagcc atccaaaacg gattgattga aagtgctcat
    33421 gactgttcag aaggtggctt ggcaattgca ctggcagaat cagctttcaa acatcagcta
    33481 gggatatctg tacagtttga attgtcctct gctcaattat ttgcagaaac tcaatcaaga
    33541 tttgtgttga cagtcgcacc ggaaaataag acacgattcg aagaaatgat gggagatgct
    33601 gctgttttag caggtaaggt gacggatgaa gcgataatcg aaatttcagc aactgacggt
    33661 cagatcaaaa tagaaactgc agtagcaaga aagtgctggg aggatgcaat cgtatgtctt
    33721 atgaagtgaa gagtttaaat gaagaatgcg ggatcttcgg tgtttggggt catccagacg
    33781 ccgctagtgt ggcatacttc gggctccata gtcttcagca tcgaggacaa gaaggtgcag
    33841 gtatcgtgtc caatgatcga ggaaagctta aggggcatcg agatttgggg ctgctttctg
    33901 aggtattcaa agatcaaaga aaattgcagc agttaacagg agaagctgca atcggacatg
    33961 tacgttatgc aacagcaggc aatggaagtg tggacaatat tcagcctttt ctattcaaat
    34021 ttcatgatca gtcgatcggc ttagcgcata atggtaactt gatcaatgct cgttccctta
    34081 gaaaagagtt agaggaaaat ggggcgatct tccattctaa ctccgatacg gagatattga
    34141 tgcatttgat ccgacgaagt gaagaaacag attttttaaa taaattaaaa agtgctttga
    34201 atgaagtcaa aggtggcttt gcctatttat taatgacaga aacggcaatg attgccgctt
    34261 tggacccaaa tggttttcgt ccattagcaa tcggacaaat gaaaaacgga gcatacgtga
    34321 ttgcctcgga aacttgtgca ttagaagtta ttggggcacg ttttataaga gatgtccagc
    34381 ctggtgagat agtgatcatc aatgacgaag gaatccagat tgattgcttt acgaaggaca
    34441 cgcagctttc tatttgttcg atggaatata tctattttgc cagaccagat tcaaacatcg
    34501 cagggatcaa tgtgcatact gcacggaaaa atatgggacg gaatttagcg aaagaatcgc
    34561 cagtaaaagc agatatggtc gttggcgtac ctaattcttc tttgtcagcc gcaagcggtt
    34621 atgcggaagc tagtggaatc ccttatgaaa tcggattagt aaaaaatcaa tacattgccc
    34681 gaacatttat ccagccaacg cctgagctaa gagagcaagg tgttcgaatg aaattatctg
    34741 ctgtacgagg agtagtggaa ggtaaaaagg tgattatggt cgatgattca attgttcggg
    34801 gtacgacaag cagacggatc gtccatcttt tgaaagaagc aggggcaaaa gaagtccatg
    34861 tgaggattgc ttctcctcct ttgaaatatc catgttttta cgggattgat attcaaacgc
    34921 gtaaagaact cattgcggca aatcacacga ttgatgaaat caaagaatgt atcggtgcag
    34981 attctttagg ttttttaagt gaagagggtc tgatcgaatc gatcggtctg gaaaaagatg
    35041 ctccgtattc aggattgtgt atggcttatt tcaacggaga ttatccgacg ccgttatatg
    35101 actatgaaga aaaatatcag gaatcactaa aagaaaaagt atcgttcttt taaaagcaga
    35161 ccaagaaggg agtatatgaa ttcaatggca aatgcatacg caaaagctgg cgtagatgtc
    35221 gaagctggat atgaagtagt agaacggatc aagaagcatg tcaaaaaaac ggaacgttta
    35281 ggtatgatgg gcgctatagg aggattcggc ggttgttttg atttatcggt ctttcaatta
    35341 aaagagccag tccttgtctc ggggaccgat ggcgtgggga cgaaattagc agtggcaatc
    35401 gaagcagaca aacacgatac aatcgggatc gactgcgtag cgatgtgtgt caatgatatc
    35461 ttagcacaag gcgcagagcc gttatatttc ttagactact tagcaacggg gaaaaatgat
    35521 ccgttacgtt tggaaaatgt agtaaaaggt gtagcagatg gatgtgttca aggaaatatg
    35581 gcgctgattg gcggagaaac agctgaaatg cctggtatgt actcaggtaa tgattatgat
    35641 ctagccggat ttgctgtagg gatagctgaa aaatctcaat tattgacagg agaaacgatc
    35701 aacccaggag atgtgttgct tggaatagca tctagcggga ttcattcaaa tgggtactct
    35761 cttgttcgca aaattttctt tgagcagcag cagttttctt tatcatcaaa actgccagaa
    35821 ttgaaaaaaa cacttggcga agaattgctt gagccaacga aaatctatgt ttcttccttg
    35881 cttccgctga tcaaagaaaa gaaaataaaa ggagctgcac atatcactgg tggagggttt
    35941 gtagaaaata tcccgcgaat gttaccagaa tctatggctg cacaaatcaa acttggctca
    36001 tggccgattc ttccaatatt cggctgttta caaaaatatg gtgaaattcc tgagatggag
    36061 atgtatgaaa tcttcaatat gggcatcggt atggtcctgg cagtcgaaga atcgaaagta
    36121 aaagaaatag tacacgaaat tgagcaagct ggcgaaaaag tttatgaaat cgggaaagtg
    36181 atcgccaaag aaaaacatcg tgtggtgttt ataggagaag aacgatgaga atcgctgttt
    36241 ttgcttctgg aaacggaagc aactttcaag cgctagccga ttatctatcg aaaaaaggat
    36301 tggaatcttc gattgactgg ttgttttgtg atcagcctga agcatatgtt ttgaaacgtg
    36361 caactgcgtt gagtgtaccg gcagattgtt tttcacctaa agaatttgat tcaaaaaaag
    36421 agtatgaaga agcaattttg cataaattga aagaaaaaaa gatcgatttg atcgtattag
    36481 ctggatatat gcgaatcatt ggaccggtat tgctgaaaaa ttatgataaa agaatcatca
    36541 atatccatcc gtctctttta cctgccttcc ctggtttgca tggcatacgt gatgcctttg
    36601 aagctggagt aaaagaaacg ggtgtcacaa ttcattatat cgaccaaggt gtagatactg
    36661 gaccaatcat ccggcaggaa aaagtgagaa ttgaacagga ggacacgttc gattctttag
    36721 aagaaaaaat ccatagagta gagcatcgaa tctatccaga agtgattagt gaaattattg
    36781 aaaatggagg ctatctgaaa tgacaagagc attgatcagt gtatcagata aaactgggat
    36841 tgtagcattc gcccaaggtt tgattgaaca aggagtagaa atcatttcaa caggaggaac
    36901 aaagcatgcg ttggataaag ctgggatcaa aacgctttcg atcgaagaag tgacagggtt
    36961 tcctgaaatg atggatggcc gtgtcaaaac acttcatcct aaaatccatg gtggtctttt
    37021 aggaagacgc gatctcccta gccatatgga ggcaatggaa acggaaaata tccaaccaat
    37081 cgactttgtt tgtgtcaatt tatatccttt caaagaaacg attatgaaac cagatgtcga
    37141 aatagcagaa gctattgaaa acattgatat cggtggtcct agtatgctcc gtagtgcagc
    37201 aaaaaaccat gaatttgtca cctctgttgt tgatccatct gactatgaag aagtactttc
    37261 agaattacgt cagtatgggc atacttcact ttctttcaga caaaaactag cggcaaaagt
    37321 ctttcgtcat actgcggcat atgatgcact gatcgctcaa tacttaacgg attgggtgga
    37381 agaaaaagaa ccggaaaaat tgacacttac gtatgaacga aaacaaacgc ttcgttacgg
    37441 tgaaaatagc catcaagccg ctgcctttta tcagtccgct cttctggaaa aatattcgat
    37501 cgcagcagca aaacaactcc atgggaaaga actttcttat aataatatcc gagatgcaga
    37561 tgctgcgcta cggatcatga aggaatatga cgagccaacg gtagtcgcct tgaaacacat
    37621 gaatccttgt ggtattggga cagcatctac gattttagaa gcgtgggaag cagcgtatga
    37681 agcagatcct gtttcaatct ttggtgggat catcgttttg aatcgagaag tagatctgcc
    37741 aacagcagaa cagatgcata agctgtttct agaaatcatc attgcccctt cttatacaca
    37801 agaagctttg gaattactgc aaaaaaagaa aaacatccga ttactgacag tagactttgc
    37861 gcaggaagaa aatcaaaatc gagaagaaac ggtctcagtc ttaggtggac ttcttgtaca
    37921 agatcaagat ctggcaatag aaaatgaaga agagtggaaa gtcgtgacaa aacgtaagcc
    37981 gactccagca gaagcaaaag cattagtgtt tgcttggaga gctgtcaaac atgtgaaatc
    38041 taatgcgatc gtactggcaa acgaacgtca gacagtagga atcggagccg ggcagatgaa
    38101 tcgagtcggt tcagtaaaaa ttgcgattga acaagcgcaa gagaaaatgg aaggtgcagt
    38161 tttagctagc gatgcttatt ttccaatgga tgattcggtt gaatatgcag ccaaacatgg
    38221 tataaaagca atcattcagc caggaggaag catcaaagac caagattcta ttgatatggc
    38281 gaataaatac gatctagcaa tggtctttac tgatgttcgg cattttagac attagagagg
    38341 agtcggataa atgaacattt tggtgatcgg tgcaggtggt cgtgaacatg caataagtaa
    38401 aaaactttta gccagtccga aggtggatac ggtgtattgt gcgccaggaa atccggggat
    38461 gacaaaagat ggtatcaatt gtgtcgctat cagtgagcga gatcattcag cgttaatcca
    38521 ttttgttaag aaagaggcta ttgattggag tatcgttggt cctgaagttc ctttgttaaa
    38581 tgggatcgtc gatgatttta tggcggaagg attgaaaatc ttcggtccga caaaagcagc
    38641 agctctgatc gaaggttcga aaagttttgc taaacaatta atggatactt atcaaatccc
    38701 gacagctaaa tccagaagtt ttgaatgtta cgaaaaagca gcagcgtata tcaaagaaaa
    38761 tggtgcgcca atcgtagtga aagcggacgg cttagcagct gggaaaggtg tagtcgtggc
    38821 taccacagtg aaggaagcgc tggatgcggc agaacaaatg ttgaaccagc atcgatttgg
    38881 ggatagtagc aaaaaaatcg tcgtagaaga gtttttggca ggagaagaat tctccctttt
    38941 ggcgtttgtc cgtaatacca aggtgtatcc gatggtcatt tcgcaagatc ataagcgggc
    39001 atttgataac gataaagggc caaatacagg cggaatgggt gcttattcac cagtaccgca
    39061 aatttcaaaa aagatgattg aaaaagctgt ggaagaagtt ttaaaaccag cggctttggg
    39121 aatgaaagaa ctaggacgct ctttcacggg tgttttatat gcgggtttga ttgctacgaa
    39181 ggaaggacca aaagtgatcg aattcaatgc gcgtttcggt gatcctgaaa cgcaagtcgt
    39241 tctttctcgg ttgaagagtg actttgcgca agtaatcgat gatttattag agaatcgtac
    39301 agtagagtta aagtggcagc aagaaggata caatgtaggc gttgtggttg cagctgccgg
    39361 ttaccccgaa gaatatgaga caggaatggt tctaccagat tttctggaag aagagctttc
    39421 tgtttactat gctggagttt cctcaaataa cggcaaacta gttggagcag gaggacgtct
    39481 ttatttagta gaagcatacg gtgagacgat caaagaagca cagaaaaaaa tttacaccgc
    39541 gttaatggat aaaacgacag atggaacatt ttatcgtaca gatattggag aaaaagctgc
    39601 caatagcgaa ctgatcgtga agtaaatcag ctgcttccat ttataaaaaa tacaacaaac
    39661 ataatcggaa gcgccgattt tagtgaagcc ttttcataaa gagtgtggta cacttttgtt
    39721 gtgtatataa ataaggagga gttcagatga aaaaaattca attaggtact tctgatcaga
    39781 aagcagctgc agtgatctta ggctgtatgc gtatcaacaa tgcggaagat ccagtaaaag
    39841 tgattgagac agcttatgaa aacggcattg atttttttga ccatgcagat atttatggaa
    39901 acggtgaatg tgaagaaatc tttgcagatg ctctagcaaa aacatcaatc aaacgagaag
    39961 atctttttat tcaaacaaaa tgtggaatcg ttccaggtgt gatgtttgat ttttctaaaa
    40021 aacatatcat tgaatctgta gaaaaaagtt tgacccgtct gaaaatggat tatgtggatg
    40081 ctttacttct tcatcgtcca gatacattgg tagaaccaga ggaagtagct gaagcgtttg
    40141 atgaattgga acggtcagga aaagttcgtt attttggcgt cagcaatcaa aaaccaatgc
    40201 aaatcgaatt gctgaaaaaa tatgttcgtc aaccattagt agctaatcag ctgcaatttg
    40261 gcttgaaaca tactggaatg atcgatcaag ggattcatgt caatatgaca gatgaagcaa
    40321 gtatcgatca tgacggtagt gtacttgatt attcccgatt gcatgatatg acgatccaag
    40381 catggtcacc ataccagtat ggattttttg aaggtgtatt tatcgggaac gaaaaattcc
    40441 ctgaattaaa ccaaacatta gaagaactag cagctaaata tcaaacgaca ccaactggct
    40501 tggcttctgc ttggatttta cgccatccag ccaatatgca agtgatcgcc ggtacgatga
    40561 acgtagggcg aatcaaggaa atcgctcaag cttcagaaat taatatgtct cgggaagatt
    40621 ggtacgaatt gtaccgtgct gctggaaaca ttttacctta aagattgtca taagcaggtc
    40681 aaaagggcta taaattaaaa agacagaata acttgaaagc tgttttcagc ttcgagatat
    40741 tctgtctttt tttattgcaa atggaaagag tatcattgta cggatttcgt ttattagtta
    40801 tttttgtttt taaggaaaag ctgtgtccga tattcttttg gagaaatccc ttgttttttc
    40861 ttaaataaat aactgaaata gttagggtca ttataaccaa tttcaaaagc aatatctgaa
    40921 atacgatagt ctgattgctg caataatttt tttgctaatt cgattctttg ttctgtcaga
    40981 taatcgatga atgtttggtt aaacgattga gaaaaaatcg tactgaaatg agagggactt
    41041 aatgcaactt gttgagcgac ccaagttaag gacatatctg gatcggtaaa attttctttg
    41101 ataaaatcca atgcatggtt caaaattggc tgatatttgt tccttgaagg ctgtgagggc
    41161 agagcagtta agaaagaaat gaacatataa actgtcgaac ggtaaagcga gtcgtcggcg
    41221 ctgattgcta agcgttgact ggtggatgtg caatgaacca tttcttgcgg gattttcttt
    41281 tctttcaggc agacatgctg gagtagctta gtcaagacaa ataaacgata taatcgtgtt
    41341 cgagttggtg tgccttgtgg tttcgtcaag tgttcgatgt acttagatac ttcgtttttc
    41401 gataatgaag acaaatcaag tgagaggtca aagtaaaaga cagaatcaac tggaagtttc
    41461 gcttcttgaa tcaaatcctc atagctgata atttgttctt taagggaact ggcggtttca
    41521 agtatcatct gcgtgatctc aaaagatgca ggtaattcgc tgattctttc tgcgacagga
    41581 ccaatggcga cagaaaaatt atttttttgt cccttttcta attcatggac caacgtttgg
    41641 gctacctgat aactggtctc gatcacattt tcttcaagag aatcaactat taaaaatttg
    41701 atgaatcgag aggaaacagc agagaagatc acttgttgat tctccctaaa taaaaacttc
    41761 aaataatcac tgagatgagc gtaatcttca aagtctgtac tgacttggtt tgctgctaat
    41821 aatacggtca tttttttccc tgctaaagag cgattgaaag attcagcaag tttcaatgtt
    41881 tcactgatcg taagtgagcc tttgaacaaa ccgttcaaga aatgattttt tttcaattcg
    41941 aaaacaagat cagaagaagt gtgcgtttct ttttgctgca aatctaaagc agttactgct
    42001 ttttctattg cttgtttcaa ttcgctactt ttaatcggtt taagcagata atcatctgcc
    42061 tgtacctgga ttgctccttt catataatcg aaatcgtcga atccactaat aaatatgaga
    42121 cgagtccaag gaagtagttt ccttgcttct tttgaaaaag tcaacccgtc catgaaaggc
    42181 atttggatat cagtcagaat gatgtcgggc tgtaagtcga taattgaaga cagtgccatc
    42241 tcaccatctc cagcttcgcc gacataagtg attggataat aagaaccaag gacagttatt
    42301 tgttcccgca agttattgcg aatgaggtat tcgtcttcga tgataaaaac tttatacatg
    42361 tttgtttcct ccaattgttt tgggagatag agggatcatc agtgtgacag ttgttccttc
    42421 tcggtatttg ctgtcaatcg tgataggttt ttgatcattt ccgtaataaa gaaggagacg
    42481 cttgtttacg ttgtaaagtc cgtagccgat actgaaatct gaatcgatcc ctttggctaa
    42541 ctctttacgt atttctgcca gtttttctgc agggatgcca atcccgttgt ctataacttt
    42601 gaattggatc atctcatcaa ttttgcatgt ggtaatacga ataaatcctt tgtgacggac
    42661 gtacttcgtt ccatggtata cagcattttc aatcaatggc tgcaagatca tttttaaaat
    42721 agaaacagga aaaagtgttt ctggtatatc gatcttatag tcaagcatat ggccgtatct
    42781 tatttttaag atgactagat aatcattgat atggctaatt tctttttcaa gaggaatcca
    42841 gtcttgtcct ttgcttaaag acgtacgaaa aaagccggaa agtgcatggg tcatagtcag
    42901 agcttcttca aagcagtctt gttcgatcaa agaaataatg gcatccaaac tgttataaat
    42961 aaaatgggga gtaatctgag cttgcaatac acgaacttca ctttgtgcta aatggtattg
    43021 tttcaaagcg ttctcccgta aagactggtt tagatcttcc gccattttat tcatgctagc
    43081 ggtaagtgtt tgtaattcca gtgtttccgg cagggttaaa cgaaagccaa ggttccctga
    43141 agaaagttgt tctgacatct cgatcagctg attgatcggt tcttggacct ttctctctaa
    43201 aaagcgacga ttctttttcg catagaaaaa aatggtacta agaactccaa gttccactat
    43261 tgttaataga atgagcgagc ggacaagtgt cgtatttttt ttgcttgcta agtcgatctc
    43321 cacacgaaca aaatcttgta agatatctga cagcagttga gtgacagaat ctacctgatt
    43381 gatgatctct tcattggtat ccataaaatc ttttgccaag atattattga tcagctcgtt
    43441 ttgataatct tccagtgtat cgatcgtacg tagcgataca tctaacgtac taatttcttt
    43501 aagtgtattt gtattatttt tgatctctcg aatatcattc ctaagttctt ctaggatatt
    43561 ttcctcattg aactcatcta cggttacttg gccagaaatc aagtcccaca tactttccaa
    43621 aactttttga tcaaccttca aagcaattgc atctgctttt tggatatttg cgatcgtctg
    43681 ttgataaatc aaaagctgtt gcgaatataa cagtatgctc agtagcaaag ggataacagc
    43741 aaatagaagc atggctttgt ttgcttgggc aaaaatctgt tttatgctta aattttttgt
    43801 catgatactt ctccagtcaa taatttctgg ttgggatgtt agctatattc tgctgggaaa
    43861 agacagtctc ggaaataaaa atatctttag gtaatgtttt tcctgtttga atatttccaa
    43921 aataacgagt aacggtattg gctacatacc agccgacatc aggtttacac tcgactacac
    43981 aattgacgat tcctgagcgt agcttctcga tcatatcttc ttgtccatca atagttacaa
    44041 tgatcaaatc ttctccaggt ttgattgatg tttcttttat cgcagctaaa gcaccgtgag
    44101 tcatttcatc actatggctg tataatacat cgatttcgga taaatcattt gtttctaaat
    44161 atcgtttcat ctggtctttt cctttcatcc gaataaaatc accgacaatt cggtgaacaa
    44221 tagtcatcgg aggtttatgg tcgatggttc catctttttt tagggttggt ttacgattga
    44281 ttgattccaa aaatccttcg gagcgtagct tggtcggtgt ggagttctct gaaccagcaa
    44341 gttctaggat tctgatttcc tgtttctttg aatttgtgaa gtgattgctg acaaataaac
    44401 ccgcccgatt tccttctgct ttgaaactgg ggccaatgtg ggtgacgaaa agctcgggat
    44461 cattcgtttg aatatgtctg tcgacaagta tgacagggat ccctgctcgc tttgcttctt
    44521 ttaatacaga gtcccacccg gattcttgca aaggagtaaa aatgatcata tccactttat
    44581 aggcaatgaa cgtccgtata tcttggattt gccgttcctg attcatgtag ccatttcggt
    44641 agagaacttg gtaatcttct ttttcaagcg cagtgataat tgattcagta tgctttttcc
    44701 gccagctact ctccgttcct gattgcgaaa aaccaacgac tagtgggtca ggtgcttcct
    44761 ttgtattagg tgtacacccc atcatttggt aagcgattac aacaagggct aaaaaaaata
    44821 aaacacgttt cactttaaat cactccatct ggatttgtta gtactatctt atcagataaa
    44881 agggaaaatc aaagtcaaaa ggaatcaatc gaaaaaaatc caagaaactt aaaaaaatcc
    44941 aagacaaaaa aagtacacct aaaaaattta aagtaaatcc cataaaaaaa tcaatgttaa
    45001 cgctttcttt attagctata ctcggtgtat caattgaaat gggggataaa aaatgaaaaa
    45061 caaatttaga aagattgttg ggactatcgc tattttgacc gcaagcattc tattaagtgc
    45121 gtgtggcaat tcaggatctg cagatgatag tacggggtat gtaggaatcg ctatgccgac
    45181 caaatcagca gaaagatgga tcgctgatgg gaacaacatg gtctcggaat tagaaaaact
    45241 gggttataaa acagatcttc aatatggaga agataaagta gaaaatcaag tagcacaaat
    45301 agaaaatatg attacaaaag gggtagatac acttgtgatt gcttctatcg atggttcggc
    45361 tttaactgat gtgttagcta aagcaaaaga agcagatatc aaggtgatcg cctatgatcg
    45421 tttactgatg aattcagaaa atgtcgatta ttacgcgact tttgataatt ttggagtagg
    45481 tgtatcgcaa gcagcttata ttgaagagca cttaggattg aaagaaggaa aaggaccatt
    45541 cacgattgaa ttatttggtg gctcgcctga cgacaacaac gcactaatca attacaacgg
    45601 agtgatgtct gttttacaac catatatgga caacggtcag ttggtcgtgc catctggaca
    45661 gacgagtttc agtcaaatcg ctacgcttcg ctgggatggt tctacggcgc aagcaaggat
    45721 ggataatctg ttaagcgcaa attatactga ccaaacattg gatgctgttt tgtcgccata
    45781 tgatccaata agtttaggaa tcatttcgtc attaaaaggc gtggggtatg ggagtgaaag
    45841 taaaccttta cctgtgatta ctggacaaga tgcgacagtt gctggcgtta aatcgatcat
    45901 tgccggggaa caaacacaaa cgatctttaa agacacacgt atcttagcaa aaaatacgat
    45961 tgaaatgatc aaagcaatca gtgatggaga agaggttccg gtcaatgata ctgagactta
    46021 tgataatggg gtgaaaactg tccctacgta tttagcaaat acagtatctg tcgataaaga
    46081 taattatcaa gcagagctga tcgacaccga ttattataaa gaatccgatc tgaaaaatta
    46141 agaggaacca aacaaggaac taaagagatc taagtcagag agaggataag aattatggcg
    46201 gattgtattt taaaaatggc agatatcacc aaaaaatttt ctggaatccg agcgttagat
    46261 tgcgtgaatc tgatgattga acgtggggaa atccatgcat tgtgcggaga aaacggagcg
    46321 ggaaaatcaa cattgatgaa tgtcttgagc ggcttgtatc catatggctc ctatgacggg
    46381 gaaatctttt atgatggaaa gctgtgtcaa tttaaagatt tgaaagatag tgaagaaaaa
    46441 ggcatcgtca tcattcatca agaattagca ctaagtcctt atctttcaat aaaagagaat
    46501 atttttctcg gaaatgaaca agcagaaaga ggcgtgattg attgggaact gacagaaaag
    46561 aaaacatatg aactgctgaa taaagtcggt ttgtctatcg acccgaatct tctagtatcc
    46621 cagattggcg tagggcaaca gcaactagtt gaaatagcta aagcattatc aaaatccgtc
    46681 cgtctgttga ttttggatga gcctaccgct gcattgaatg aagaagaaag cgcgaatttg
    46741 ctgagattga tccgagagtt gaaagagcaa ggtgtaacct ccatcattat ttcacataag
    46801 ctgaatgaaa tcgtggatat cgcagatcga atcaccattt tacgggatgg acagacgatt
    46861 gagacactag aaaatgaaat gatcagcgaa gagcatatta ttcgcggaat ggtgggcaga
    46921 gatttagttg atcgttatcc tgaaagaaaa ccggatattg gagaagttta ttttaaagta
    46981 gaagactgga cggtctatca ccctcttgat cacgagcgaa tcataaacga ccacatcaac
    47041 ttgcatttga aaaaaggaga gattgtagga atagctggac tgatgggagc gggcagaact
    47101 gaattcgcta tgagtctatt tggacattct tatggaagca agatatccgg acgtatatta
    47161 aaggaagggg cagagatatc agttaagacc gttccttcag ccattgcaaa cggactcgct
    47221 tatgtctcgg aggaccgaaa atctttagga ctgaatctgc tgatggatat tcgggaaaac
    47281 gtgacgctga gcagtttgga taaaataagt caaaaaggag tattagataa agaaaaagaa
    47341 gtaactgagg cagaaaattt ccggaaaaag atgcgtataa aaacaaactc catccatcaa
    47401 attgtcagta gtcttagtgg tgggaatcaa caaaaagtcg ttttatccaa gtggctgatg
    47461 acacaacccg atattctttt tttggatgag ccaacccgtg ggatagatgt tggggcaaaa
    47521 tatgagatct acacgattat cgaagaaatg gcagcaaatg gcaaagctgt ctgtcttatc
    47581 tcttctgaac ttcctgaaat attagggatg tgtgatcgaa tctatacgat gaacgaagga
    47641 cgtattacag gagaagtctc gcgagaagat gcagatcagg aagtcttgat gaaattaatg
    47701 acgaaagaag aggtgggtta agttggaaca ggcaaaaaat cttacggata aaaaagagaa
    47761 aaaactaaat ttgaaaagta gagcagctga tctttttggt cgctacagca tggtgatcat
    47821 tttagcggga ctacttattg cgtttcaatt gatgacggat ggtattttct ggcgtccatt
    47881 gaatataact aaccttgttc tgcaaaatag ccatatatta gtactagctg cagggatgtt
    47941 attagttgtg ctcttaggtc atgtggattt gtcggtaggg tcagtgatgg cgtttgttgg
    48001 tgcaattgcg ggcatgatga tggtcaatcg ccaaatgaac ccgtggatga cagttatcgc
    48061 atgtcttgca gtaggcgggc tgatcggcgc atggcaaggt ttttgggtag cttatgcagg
    48121 gataccggcg tttatcgtga ctttagcagg attgctgatg tttcgtggac tgacacaagt
    48181 tgttctagga ggccaatctc tagcaccttt tccagctgtt ttccaaaaaa tgtctacggg
    48241 ttatttacca gacttaagcg aaggaagcag ccttcacttc ttgacattga ttttaggaat
    48301 gatcatcacg atcgtgttag ttgttggtca atggcgaaca agaaatcgtc ggaaaaatca
    48361 tttatttgaa gtggaatctc caacagcttt cttggtaaag gcggtattta cagcagtcgt
    48421 tgtactagga ataacttata tctttgcctc ttatcaaggg tatccgatta ttttgatcat
    48481 tcttggtttg atcgttgcag catatgggtt tttgacaaat aaaacagtag caggtcgaca
    48541 gatttatgcg acgggcggaa atcgaaaagc ggctgaacta tcagggatca aaacaaagcg
    48601 aatcacgttc tgggtattcg tcaacatggg agtcatggca gctttagctg gattagtttt
    48661 agctgctcga ttgaatgcgg caacacctca agcaggtaca tcgatggaac tggatgcaat
    48721 ggcggcagta tattttggtg gtgcttcgac ttccggcggc attggaacaa tcatgggtgc
    48781 gattgtcggt ggcttggtca tgggtgtatt gaacaatggc atgtcgattt taggcgtcgg
    48841 ggtagactgg cagcaggcaa tcaaaggatt gatcttgctt ttagccgttg tgctagactt
    48901 gtataataag aaaaaacgaa caacgtagga gaacgccggt tattcagaaa aaagactgtg
    48961 acaagacatt tgtcacagtc tttttttcgc taaaagcgaa cattcattgt ttcgtttgta
    49021 tagactaaaa ataatatatg tttttttacc attcgtataa attctctttt tgctcttgat
    49081 ttttttgctt aattgagtta aattacatag ggcgctaaaa aaagccttga ttaaattaat
    49141 aatgttcgtg ttttgctgga tgtgaacatc aggaggataa tgtaatgaaa gtatttgatt
    49201 acgaagatat tcaattaatt cctaataaat gtatcgtaaa tagccgttct gaatgtgata
    49261 caacggtcac attaggtaaa catacattca aaatgccagt agtgcctgcc aacatgcaga
    49321 cgattattga tgaaacaatc gcagaattct tagcggaaaa tggttatttc tatatcatgc
    49381 atcggtttga tgaagcagct cgaattccgt ttatcaaaaa aatgaaaaag cgtggattga
    49441 ttacctcgat cagtgttggc gtcaagaaag aggaatattc ctttatagag aagttggcag
    49501 aagaatcgct aaatcctgat tatatcacta tcgacatcgc gcatggacat gctaactcag
    49561 ttattgatat gattcagcat attaaaaaat atttgcctga aacttttgtg attgccggta
    49621 atgttggtac accggaagcc gtccgtgaat tggaaaatgc gggcgcagat gcaacaaaag
    49681 tcgggattgg tccaggaaaa gtatgtatta caaaaatcaa gacaggcttt gggactggag
    49741 gctggcaact ggcagctctt agatggtgtg cgaaagcagc tcgcaagccg atcatcgctg
    49801 acggtgggat cagaacacat ggcgatattg caaaatctgt ccgttttggt gcgacaatgg
    49861 tcatgattgg ttcattgttt gccggtcacg aggaatctcc tggcgaaaca aaagtcgaaa
    49921 atggaatcgt gtataaagaa tactttggtt ctgcttcaga attccaaaaa ggcgaaaaac
    49981 gaaatgttga aggaaagaaa atctggatcc aacacaaagg atctttgaaa gatacactag
    50041 tggaaatgca acaagacctt caatcatcta tttcttatgc tggaggaaga gatctggaag
    50101 ccattcgaaa agttgactat gtcatcgtga aaaattcgat ttttaatgga gacacaatct
    50161 aaaaaataaa taaaatatta ggatgttgtg aaaaagttgt cctgcattaa gtaataagaa
    50221 cagccaaaca aaaatagttc tttatatgtt ttgtttggct ggaattatta tcgcagatac
    50281 aagcttttga acatcattat tcagaataag ggactgtgat aagatttttg tcacagtccc
    50341 ttatgttttg caaaaaaagt ttttcttttt tctcgtaaat tcggtaaaat caaaagaaaa
    50401 aatagacaat agaaaagaga agcttatgtg ggaaaaagta gagaaaaaac aaggaccgat
    50461 ttatcgtcaa attatggaac agattatgag agaaatcgaa aacggaagga tcaatcctgg
    50521 aagtcaactt gaatcagaac gaaaactagg gcaacttttt ggtgtgaatc gttccaccgt
    50581 tgtccatgca ttggaagagc ttagggagct tggggtacta acgagcaaac gtggcagcgg
    50641 atggtttgtt aatcagactg aatgggggaa attcgctgtt ccaagaatcg attggcggca
    50701 aatgatctct cctcgttatg agcagacgga ctggtatgag caaaaaataa gagaagcaaa
    50761 gcagatccaa aaaacatcgt ttcttgattt atacgctagc gagatgccag atgagctttt
    50821 gccgaatttt gagtttcctt cttattctct tgaagaaatc ttagcggaag aaaaagaaat
    50881 ggatctttta ggctatactc cgttacgtaa caaaatcaaa cggtatttgg aaagtaaatt
    50941 tgaattggca ttttccccca accagcttct tgtgactggt ggcggtcagc aagcaatctt
    51001 tttgatttta caaacgattc tttcagctgg agaggggata gctgtagagt caccttcttt
    51061 tttttaccga ttacctcttt tcaaagcttc aggaacgcgt ttatttggga taccgatgga
    51121 tgaagaaggg atcgacttag aaaaactgaa agaatcgatc cataaaaata aattgaaagc
    51181 agtgcttatc aacccgaatt ttcaaaaccc tacaggaaaa gtgatgagtc aaaaacgacg
    51241 agaaaagcta gtagaattgt gtcgacagta tcggcttcca attattgaag acgatgtatt
    51301 tacggatctt tcatttctaa accaagaaga agtccttcct atacgaacga ttgatccgga
    51361 taatgtgtta tacgtcggtt cgttatctag ggttttagga aaaacaacga aaatcggttg
    51421 ggtgatagga cctgagactt ttatctcgca actagctcaa gcgcaagaaa tgatggagtt
    51481 ttcgatgaat atccttacac aaatcacagt ggctaatgta tttaatgaag caattgattt
    51541 gaaaatgcaa gatgtaagaa aaaagttgaa agaaaaaagc cgactgataa gcgcttgggg
    51601 agattcacaa tcgtttttca agcttcattc aattttaggt ggttactatg cctggattac
    51661 ttgggatggg aaaaaactag accccgaact agcagaaaaa gtagtagata tgggtcttgg
    51721 aattgcacca agtctacttt ttgggcaaga tataaatgga atcagaatca attacagtag
    51781 gctggatgaa aaccaaatac cgttgtttta ttcaaagatg aaaattctag aaaagtggtt
    51841 aacagaataa tttcacaaag taaatagatt aaagaatata acagcttgga tttaaatttc
    51901 aagctgtttc ttttttttcg gaaaaagaat acgatataaa gaaactaaga aaaaaccatt
    51961 atttgtacgt ccgttcacga tgtgtaaata aaataaatgt ttgcaacaaa actgtataac
    52021 accaacgttt ttaaatagaa acagatggtt gtaagtttga ttagaaaata gaaaaaatgc
    52081 agatgaaata taaaacgctt tccttattgt gattttattc actaatgctg ttaatatgcg
    52141 gattggcata atttcctttc atcgtgaaaa tttgtgcttt tagcttgtat ttctcataaa
    52201 tccatgataa tttattaatg aagacggtta aatagtgata cagttttatt cactgtttca
    52261 atcgcagaat gaagagattt tcttatagat gagagaggaa tgtgtgacaa atggcaaaca
    52321 aaaaagcacc gatcgacttc caagcactgc tagatgaagt caatgcagat ttcccagtat
    52381 atcaagcact tgatcaagat ggaaacgtag ttaacaaaga tttagtacct gatttatccg
    52441 atgatgaact cgttgaatta atgactcata tggtatggtc tcgtgtatta gaccaacgtt
    52501 caacagcgct gaaccgccaa ggacgcctag gcttttttgc accaactgct ggacaagagg
    52561 caagtcagct ggctagtgct tacgcatttg ataaagaaga tgttcttctt ccaggttatc
    52621 gggatgtacc tcaactagta aaacatggtt tacctttatc tcaagctttt ttatggtctc
    52681 gaggacatgc tgcaggtaat tcttatccgg aagaattgaa agctctacca ccacaaatta
    52741 tcatcggtgc acaatatgta caagcagccg gtgttgcatt aggtttgaag aaacgaaaca
    52801 agaaaaatgt cgtcttcact tatactggtg atggcggttc atcacaaggt gatttttacg
    52861 aagcaatcaa tttcgctggc gcttaccatg caaatgccgt attttatatc caaaacaacg
    52921 ggtatgcgat ctctacacct cgtgaaaaac aaactgcagc aaaaacactt gcacaaaaag
    52981 ctgtcgcagc tgggattcct ggtattcaag tcgatggaat ggatccgctt gcagtatata
    53041 ctgtatctaa aatggcacgg gaatgggcga tcagtggaaa tggaccagtc ctaatcgaaa
    53101 cactgactta tcgttatgga ccacatacac tatctggtga cgatccaacc cgctaccgta
    53161 caaaagacac agatgacgat tggcagaaaa aagatccatt gatccgcttc cgtaaatatt
    53221 tgacggaaaa aggactttgg tctgaagaaa aagaagaaca agtcatcgaa gcaactaaag
    53281 aagaaatcaa agcagctatt gctgaagccg acaaagtacc aaaacaaaag gtttcagatt
    53341 tcttgaaaaa catgttcgaa gtatctccac aatcaatcaa agaacaaatt gcaatttatg
    53401 aagcgaagga gtcgaaataa tcatggcaca aaaaacaatg atccaagcaa tcacagatgc
    53461 cttagcactt gaactagaaa atgacgagaa tgtcgttgtt tttggtgaag atgttgggaa
    53521 aaacggagga gttttccggg caactgaagg attgcaggaa aagttcggag aagaccgagt
    53581 attcgatact cctttagctg aatctggaat cgcaggattg agtttcggtc ttgcgttaga
    53641 aggatttcgt ccagttcctg aaatccaatt ctttggtttt attttcgaag caatggacga
    53701 agtagtagct caaatggctc gtacaagata tcgaatgagc ggcactagaa atctacccat
    53761 cacaattcgt tcgccatttg gtggcggtgt tcatacacca gaattgcatt cggataattt
    53821 agaaggtttg atcgctcagt ctcctggtat tcgagtagtg attccttcca acccttatga
    53881 tgcaaaagga ctattgattt cttctattag aagtaacgat ccggttgttt tcctagaaca
    53941 catgaaacta tatcgctcat tccgagaaga agtgccggat gaagcttacg aagttccttt
    54001 ggataaagca gcagttactc gtgagggaac agatgtatct attatcacat acggagcaat
    54061 ggtgcgtgaa gcaatcaaag cagcagacaa tcttgcaaaa gaaaatatat ctgttgaaat
    54121 cattgatctt cgtacagttg cgccattaga tgtagaaacg atcattcaat ccgtggaaaa
    54181 aactggtcgc gtagttgttg tccaagaagc acaacgacaa gcgggcgttg ccgcgcaagt
    54241 agtttctgag atctcagaac gcgctatcct ttcattagaa gccccaatcg gacgagtttc
    54301 tgcacctgat acagtcttcc catttggaca agcagaaaat gtctggttgc caaatgcaaa
    54361 agatatcgaa gacaaagtaa aagaaatcgc ggaattttaa gaaaagaagg gacgaaacaa
    54421 agtcatggct tatcaattta aattgccgga tatcggtgaa ggaatcgcag aaggtgaaat
    54481 cgtcaaatgg ttcgtcaaac caggagatac gatcaatgaa gatgatacat tactagaagt
    54541 tcaaaatgac aaatcagtag aagaaatccc gtcacctgtt acaggaacgg ttaaaaatgt
    54601 gattgttcca gaaggtaccg tagcaaatgt tggggatgta ttagtagaaa tcgatgcacc
    54661 aggacacgaa gacaatgaag gggacagtgg tgtagccgca gaatcccaaa ctccagctaa
    54721 accggctgct gaacccactg ttgatacaga atcagctgga tcgtcaagcg aaggagtctt
    54781 ccaatttaag ttaccggata tcggtgaagg aatcgcagaa ggtgaaatcg tcaaatggtt
    54841 cgtcaaacca ggagatacga tcaatgaaga tgatacatta ctagaagttc aaaatgacaa
    54901 atcagtagaa gaaattccgt cacctgtcac agggacagtt aaaaacgtga ttgttccaga
    54961 aggcactgta gcaaatgttg gggatgtatt agtagaaatc gatgctcctg gacacaatag
    55021 tgcaccgtca actagtgcgc catcagctga agcaccaaaa gaaaaagtgg aaacatcagg
    55081 ttcagcaagt gtcgttgaag ctgccgatcc aaataaacgt gtattggcta tgccatctgt
    55141 tcgtcaattt gcccgtgaaa aagatgtaga tatctcacaa gtaactgcaa ctggaaaagg
    55201 tggcagagta acaaaagagg acatcgaaaa cttcttggca ggtggtccaa gcagtgcacc
    55261 agcgaaatca gaagcgccag aagcggcagc accgaaagaa gcagctcctg cagcagaaag
    55321 caaaccagct gcaccagcaa aaccattcaa gtccaactta ggagacttgg aagaacgtgt
    55381 agcaatgacg ccaacacgta aagctatcgc taaagcaatg gtcaacagta agcatacagc
    55441 tccacacgtg acattgcatg atgaagtaga agtgtctaaa ctatgggata atcggaaacg
    55501 atttaaagaa gttgctgctg caaatggtac gaaacttact ttcttgccat atgtcgtgaa
    55561 agctttaaca gcgactgtta agaaataccc agtattgaat gcatctatcg acgatgcaaa
    55621 ccaagaaatc gtttataaac attactacaa tatcggtatt gcaactgata cggatcacgg
    55681 actatatgta ccaaatgtga aagatgcaga ccgcaaagga atgtttgcta ttgcagacga
    55741 aatcaatgag aaagcaaaat tagctcatga cggcaaacta tctgcagaag atatgcgcaa
    55801 tggaacaatt acgatcagca atatcggatc tgtaggtggc ggttggttta caccagtcat
    55861 caactatcca gaagtagcta ttttaggtgt aggaacgatt gcacaacaac caatcgtaaa
    55921 tgctgaaggc gaaatcgttg tcggtcgtgt gatgaaactg tcattaagtt tcgatcaccg
    55981 tatcgtagat ggagcaactg cgcaacaagc aatgaataat atcaaacgtc ttttagctga
    56041 tccagagcta ttaatgatgg aaggatgata aacaaatggt agttggagat tttgctgtag
    56101 aattagatac agttgtaatt ggtgcgggac ctggtggcta tgtagctgcc atccgcgctg
    56161 ctgaaatggg acaaaaagta gcaatcattg aaagagagta tattggcggt gtttgtttga
    56221 atgtcggctg tattccttca aaagcactga tagctgcagg acaccattat caagagtcac
    56281 tagattctga aatgtttgga gtaactagtg aaaacgtcaa actagatttt gcaaaaacac
    56341 aagaatggaa agaaaacaaa gttgtccata cgttgacttc tggtgttggt ttcctattaa
    56401 aaaaacataa ggttgaaaca atcgaaggag aagcgttctt cgtagatgat cacacactac
    56461 gcgtcattca tccagattca gctcaaactt attcgttcaa taacgcaatc atcgcaacag
    56521 gttcccgtcc aatcgagatt ccaggattta aattcggagg acgtgtgtta gattctactg
    56581 gcggattagc attgaaagaa gtacctaaga aatttgtgat catcggtggc ggtgtgattg
    56641 gtgccgaatt gggcggagcg tacgcaaact taggagcaga agtaacgatt cttgaaggct
    56701 caccacaaat tttaccaact tacgaaaaag atctagtaaa attagtagaa gatgatttca
    56761 agaaaaaagg cgtaacagtc gtaacgaatg caatggcgaa agaagcagtc gataacggtg
    56821 acagcgtgac agtgaaatat gcagtggacg ggaaagaaga atccgttact gctgattatg
    56881 tgatggtcac tgtaggtcgt cgtccgaata cagatgatat gggcttagaa caagcgggtg
    56941 tcgaagtagg agaacgagga ttgatcacgg tggataaaca aggacgtacg aacgtaccta
    57001 acatctatgc catcggtgat atcgttccag gggcggcatt agcacacaaa gccagttatg
    57061 aagcaaaaat cgctgctgaa gcaatctctg gcaaaaaagt agctgtagat tataaagcaa
    57121 tgccggcagt agccttcact gatcctgaat tggcttctgt aggtatgacg atcaaagaag
    57181 caaaagatgc tggtatcgaa gcaaaagcat ataaattccc attttcaggg aacggtcggg
    57241 cattatcgct tggtaaaaca gaaggattca tccgtctagt tacgacgatc gaagataacg
    57301 tgcttattgg cgcgcaaatc ggtggagtcg gcgcaagtga tatggtctct gaattagctt
    57361 tagcaatcga atcaggaatg aatgctgaag atatcgcctt gacgattcat cctcatccat
    57421 ctcttggcga aatcgtcatg gatgcttcgg aattagcatt aggtttacca atccatattt
    57481 gatttgaata atacaggcga aacgcaactg aaaaatcagt tgcgttttgt tttttagaat
    57541 tatcaataat attattatgt aaacttaaaa atatgacaac ttcttggttt attaccactt
    57601 cctatgctac actgaagagg aatatgaaat aggagagttg aagatgcaag aatatcagta
    57661 tccacttgat ttagattgga caacagacga aatggtcatt gtaatgaaga tgtgggaaga
    57721 tctggaacgt gcgaatgaaa aagggataaa caatgaagct tttttgaaga cttatcagca
    57781 gtttaaaact gttgtcaaat ccattggtga ggaaaaacga ttgggacggg aatttgaaaa
    57841 agcttccggt tattctttat atcgtacagt gcagcaagca aaaaaaaatc caaacaaaac
    57901 tttgagaatg aacgggtgag ataaatggaa cagatgattg atcatatcaa gtcctggctt
    57961 gaagaagctg gtgagaaaat caaatcttct caacaaacat taacaatctc gcaaaaatca
    58021 aatcgaacgg atctagtaac aaatgtcgat cgaaacatcc agaattttct aatcgaaaaa
    58081 atccattcct ttgatccaga ggcgaaaata ttggcagaag aagaagggtg taatcaatta
    58141 tcggatctcg atggaagagt ctttatcatc gatcctattg atggcacctt gaattttgtg
    58201 attgaagggg aaaatttttg tattatgctc gctgtttatg aatccggcgt tggaaagctt
    58261 ggtttcattt atgacgtgat gagaaatgaa cttttttggg gtggaaaagg aataggcgtg
    58321 tataaaaatg atgagccatt gcctagacca gcaaataaat ccttatcgga aggcttactt
    58381 ggtgtgaata gttatctttt cggtcataat aaatatggaa tccgagaaat tgcggaaagc
    58441 agcatgggga cacgtatgta cggatgcgct ggtcttgaac tagtggcaat cttgaaagga
    58501 aaccacattg cttatatttc aaaccttagc ccttgggatt atgcagcggg aaatgtctta
    58561 ttggaagagt ttggtatggt aacaagcggt ctttttggta ctcctttgac atttgaaaaa
    58621 agggaatact atttagcagg gacttcttgt gcatatgcag aaatcgcaga ccttttgaaa
    58681 aaagaaggct gaaaaaaagg tagaaatcat tcacaaaaat gataaaaacg agcaaaagat
    58741 taattttctc gaaaaaatga aaacatttta ctatatttca tgaaaaaagt ctgctataat
    58801 tagcagtcga gtaaaatttg ccctgtcata aagaaccaat aaaaaaggag ttagttacat
    58861 tgaattatag aaacgatatc cgtaacgtcg caattattgc ccacgttgac cacggaaaaa
    58921 caacattagt tgatgaacta ttaaaacaat cagatacatt agacgcacat acgcaattgc
    58981 aagaacgtgc gatggactca aatgcgctag aaaaagaacg tggtatcacg attttagcca
    59041 aaaacacagc tgtagactat aaaggtattc gcgtaaacat catggatact ccaggacacg
    59101 cggacttcgg tggcgaagta gaacggatca tgaaaatggt tgacggcgtt gtgttggtcg
    59161 tagatgcgta tgaaggaaca atgcctcaaa cacgttttgt attgaaaaaa gcactggaac
    59221 aacatatcac accaatcgtt gtcgtaaaca agattgacaa accttctgct cgtcctgagc
    59281 atgtcgtaga tgaagttctt gaactattca tcgaattagg agcagatgat gatcagttag
    59341 actttcctgt gatttatgca tctgcactaa atggtacgtc aagcttgtca gatgatccag
    59401 cagatcaaga accaaccatg gcacctattt ttgatacaat tattgaaaaa atccctgctc
    59461 ctgtcgataa cagcgacgaa ccattacaat tccaagtttc attacttgac tacaacgatt
    59521 atgtaggtcg tatcggaatc ggacgtgtat ttagaggaac aatcaaagta ggagaccaag
    59581 tagcattaat taaattagac ggaacagtta agaaattccg tgtaacgaaa ttatttggtt
    59641 tctttggact aaatcgtcta gagattcaag aagcaaaagc tggagacttg attgctgtct
    59701 caggtatgga agatatcttt gtcggtgaaa cagttactcc tgtggatcat caagatgcgt
    59761 tacctatcct tcacattgac gaaccaacat tgcaaatgac tttcttagtt aataattcac
    59821 catttgccgg tcgagaaggt aaattcgtaa ccgctcgtaa gattgaagaa cgtttgatgg
    59881 cagaacttca aacagatgta tccttacgag ttgaaccaac aaactctcca gatgcatgga
    59941 cagtttctgg tcgtggagaa ttgcatttgt ctatcttgat tgaaaacatg cgccgtgagg
    60001 gatacgaatt gcaagtatct cgtccagaag ttattgaaaa agaaatcgac ggtgtaaaat
    60061 gcgaaccgtt tgaacgcgtg caaatcgata caccagaaga atatatgggt agtgttatcg
    60121 agtccttgag cttacgtaaa ggtgaaatgc aagatatggt ccatacagga aacggacaaa
    60181 tccgtttgac attcttaaca cctgcccgcg gtttgattgg ttattcaact gaattccttt
    60241 caatgacacg tggttacgga atcatgaacc atacttttga ccaatatctg ccaatgcttc
    60301 ctggtcaaat tggcggacgt caccaagggg cgcttgtttc gatcgataca ggaaaagcaa
    60361 cgacttattc tatcatgagt atcgaagaac gcggtacagt cttcgtagaa ccaggtacag
    60421 aagtatatga aggaatgatt atcggggaaa acagccgtga taatgatttg actgtcaaca
    60481 tcacgaaagc aaaacaaatg acaaacgtac ggtctgctac taaagaccaa acatctgtca
    60541 tcaaaaaacc aaaacaattg acgttggaag aatctttgga attcttgaat gatgatgaat
    60601 attgcgaagt aacaccagaa agcattcgct tgagaaaaca aattttagag aaaaatgctc
    60661 gtgaaaaagc atctaaaaag aaaaaataat ctgtaaaagg atgaagagag aaaccagctt
    60721 gttataaaaa aggctctttg tcaataagga ctgatgagtt gtgcaaaatc aaatctgagt
    60781 cagaatgaac cacattctgg ct
//
LOCUS       DACDLM010000009        60347 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.009, whole genome shotgun sequence.
ACCESSION   DACDLM010000009 DACDLM010000000
VERSION     DACDLM010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 60347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60347
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.009"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..107)
                     /locus_tag="IV356_000580"
     rRNA            complement(<1..107)
                     /locus_tag="IV356_000580"
                     /product="16S ribosomal RNA"
     gene            26..169
                     /locus_tag="IV356_000581"
     CDS             26..169
                     /locus_tag="IV356_000581"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014297.1"
                     /translation="MEKEAFDLHVLGTPPAFVLSQDQTLIKSSNNLAIVKLNLFASIL
                     LAC"
     gene            complement(629..1939)
                     /locus_tag="IV356_000582"
     CDS             complement(629..1939)
                     /locus_tag="IV356_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAP9014298.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1951..3369)
                     /locus_tag="IV356_000583"
     CDS             complement(1951..3369)
                     /locus_tag="IV356_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP9014299.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3609..5177)
                     /locus_tag="IV356_000584"
     CDS             complement(3609..5177)
                     /locus_tag="IV356_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HAP9014300.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(5181..5591)
                     /locus_tag="IV356_000585"
     CDS             complement(5181..5591)
                     /locus_tag="IV356_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HAP9014301.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5588..6511)
                     /locus_tag="IV356_000586"
     CDS             complement(5588..6511)
                     /locus_tag="IV356_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HAP9014302.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6508..7386)
                     /locus_tag="IV356_000587"
     CDS             complement(6508..7386)
                     /locus_tag="IV356_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAP9014303.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7373..8710)
                     /locus_tag="IV356_000588"
     CDS             complement(7373..8710)
                     /locus_tag="IV356_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAP9014304.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8713..9816)
                     /locus_tag="IV356_000589"
     CDS             complement(8713..9816)
                     /locus_tag="IV356_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAP9014305.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9890..11398)
                     /locus_tag="IV356_000590"
     CDS             complement(9890..11398)
                     /locus_tag="IV356_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP9014306.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11364..12056)
                     /locus_tag="IV356_000591"
     CDS             complement(11364..12056)
                     /locus_tag="IV356_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAP9014307.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(12078..13052)
                     /locus_tag="IV356_000592"
     CDS             complement(12078..13052)
                     /locus_tag="IV356_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP9014308.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13352..14224
                     /locus_tag="IV356_000593"
     CDS             13352..14224
                     /locus_tag="IV356_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP9014309.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14682..16880)
                     /locus_tag="IV356_000594"
     CDS             complement(14682..16880)
                     /locus_tag="IV356_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP9014310.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEIEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            17112..18104
                     /locus_tag="IV356_000595"
     CDS             17112..18104
                     /locus_tag="IV356_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP9014311.1"
                     /translation="MVTIKDVAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            18164..19585
                     /locus_tag="IV356_000596"
     CDS             18164..19585
                     /locus_tag="IV356_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HAP9014312.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSLPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19578..21077
                     /locus_tag="IV356_000597"
     CDS             19578..21077
                     /locus_tag="IV356_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009224330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HAP9014313.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            21116..22510
                     /gene="uxaC"
                     /locus_tag="IV356_000598"
     CDS             21116..22510
                     /gene="uxaC"
                     /locus_tag="IV356_000598"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HAP9014314.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22669..23352
                     /locus_tag="IV356_000599"
     CDS             22669..23352
                     /locus_tag="IV356_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HAP9014315.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23354..24190
                     /locus_tag="IV356_000600"
     CDS             23354..24190
                     /locus_tag="IV356_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAP9014316.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            24201..25955
                     /locus_tag="IV356_000601"
     CDS             24201..25955
                     /locus_tag="IV356_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9014317.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(26231..26572)
                     /locus_tag="IV356_000602"
     CDS             complement(26231..26572)
                     /locus_tag="IV356_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAP9014318.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26640..28811)
                     /locus_tag="IV356_000603"
     CDS             complement(26640..28811)
                     /locus_tag="IV356_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAP9014319.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            29022..29879
                     /locus_tag="IV356_000604"
     CDS             29022..29879
                     /locus_tag="IV356_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAP9014320.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            complement(29950..30807)
                     /locus_tag="IV356_000605"
     CDS             complement(29950..30807)
                     /locus_tag="IV356_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP9014321.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30792..33494)
                     /locus_tag="IV356_000606"
     CDS             complement(30792..33494)
                     /locus_tag="IV356_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAP9014322.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33507..34796)
                     /locus_tag="IV356_000607"
     CDS             complement(33507..34796)
                     /locus_tag="IV356_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HAP9014323.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34946..35992
                     /locus_tag="IV356_000608"
     CDS             34946..35992
                     /locus_tag="IV356_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP9014324.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35994..38147
                     /locus_tag="IV356_000609"
     CDS             35994..38147
                     /locus_tag="IV356_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAP9014325.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(38620..40071)
                     /locus_tag="IV356_000610"
     CDS             complement(38620..40071)
                     /locus_tag="IV356_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP9014326.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(40068..41792)
                     /locus_tag="IV356_000611"
     CDS             complement(40068..41792)
                     /locus_tag="IV356_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP9014327.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(41785..42399)
                     /locus_tag="IV356_000612"
     CDS             complement(41785..42399)
                     /locus_tag="IV356_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAP9014328.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(42744..44201)
                     /locus_tag="IV356_000613"
     CDS             complement(42744..44201)
                     /locus_tag="IV356_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP9014329.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(44242..45162)
                     /locus_tag="IV356_000614"
     CDS             complement(44242..45162)
                     /locus_tag="IV356_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP9014330.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(45174..46121)
                     /locus_tag="IV356_000615"
     CDS             complement(45174..46121)
                     /locus_tag="IV356_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP9014331.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(46600..47319)
                     /locus_tag="IV356_000616"
     CDS             complement(46600..47319)
                     /locus_tag="IV356_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAP9014332.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(47368..49014)
                     /locus_tag="IV356_000617"
     CDS             complement(47368..49014)
                     /locus_tag="IV356_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAP9014333.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            49193..49783
                     /locus_tag="IV356_000618"
     CDS             49193..49783
                     /locus_tag="IV356_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP9014334.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            49875..51380
                     /locus_tag="IV356_000619"
     CDS             49875..51380
                     /locus_tag="IV356_000619"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HAP9014335.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(51464..52816)
                     /gene="celB"
                     /locus_tag="IV356_000620"
     CDS             complement(51464..52816)
                     /gene="celB"
                     /locus_tag="IV356_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAP9014336.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(52816..53334)
                     /locus_tag="IV356_000621"
     CDS             complement(52816..53334)
                     /locus_tag="IV356_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014337.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(53350..53676)
                     /locus_tag="IV356_000622"
     CDS             complement(53350..53676)
                     /locus_tag="IV356_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HAP9014338.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(53689..55668)
                     /locus_tag="IV356_000623"
     CDS             complement(53689..55668)
                     /locus_tag="IV356_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAP9014339.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(55689..56003)
                     /locus_tag="IV356_000624"
     CDS             complement(55689..56003)
                     /locus_tag="IV356_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HAP9014340.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            56171..56464
                     /locus_tag="IV356_000625"
     CDS             56171..56464
                     /locus_tag="IV356_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HAP9014341.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(56542..57654)
                     /locus_tag="IV356_000626"
     CDS             complement(56542..57654)
                     /locus_tag="IV356_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP9014342.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            58041..58220
                     /locus_tag="IV356_000627"
     CDS             58041..58220
                     /locus_tag="IV356_000627"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014343.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            58414..58584
                     /locus_tag="IV356_000628"
     CDS             58414..58584
                     /locus_tag="IV356_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP9014344.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(59008..59973)
                     /locus_tag="IV356_000629"
                     /pseudo
     CDS             complement(59008..59973)
                     /locus_tag="IV356_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="collagen binding domain-containing protein"
     gene            complement(60010..60347)
                     /locus_tag="IV356_000630"
                     /pseudo
     CDS             complement(60010..60347)
                     /locus_tag="IV356_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340556.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT        17967 a        12375 c        10567 g        19438 t
ORIGIN      
        1 tctttttccg gtggagcaag ctccggtgga aaaagaagcg ttcgacttgc atgtattagg
       61 cacgccgcca gcgttcgtcc tgagccagga tcaaactctc ataaaaagtt cgaacaatct
      121 tgcgattgtt aagctcaatt tgtttgctag catattgctt gcttgttaaa aatgtttatt
      181 gtcttgaatt gaatcaagac gccctacaca tttggtttgt cttactttgt tcagttttca
      241 aaggtctact tcatcgagag tgtttcccga ttcatttttg gctgccgtag caacttttat
      301 atcatatcag agagacaaac gattgtcaac tcttttttaa aagttttttt cgatttcgtt
      361 tttcgaaatc tttcagcaac tcatttatca taacttatcg tttgttattt gtcaagaact
      421 tttttgaagt ttttttcgat agaatcaagc ttcgcaagtg gttcttttta acgacttagt
      481 tatcttatca cgtctaaaaa catgtgtcaa ctcttttttg gaattttcat aaaatgtttc
      541 aatgaagcgc gacaacgttg tttaatatat cattaaaaaa aataaaggtc aagctaaaat
      601 attatttaag cttgacctta ttataatttc aacgattgtc aaaagtattg tttgcagctg
      661 tgttgccagt ttctatagat aaatcacagc ttttgaaaca taagttttgt actgcttcga
      721 ttcgcccgaa ttcttttgca gttatttggc aatgagaaaa gcagacatct tctataggct
      781 tttcaggaaa tgctactaaa tcaaaagctc gggaaggaag tgagtaacct ggagaaaggc
      841 atgcctgtac gtttttgatg tgtatgtctt tgactttcgt catttgcttt gattcaggta
      901 tttcttcagc cactgcttgc caactttctg gcatttgagc aaggtcattg ctattttttc
      961 tattgtattc attatgccag tccattatcc aagaaaaagg aaattgtaca tcaatcatat
     1021 tcagattttc taccctgata ttttcgatca ctccccctct ttcttttgaa gatttcattc
     1081 gaataccaca gtctgactga aaaaaatcga tatcgtgaat atatacgtca ctaactccag
     1141 cactaacttc gctaccaata gttacaccgt atcctgaacg gattttacat ctagcaacct
     1201 cgattcttga tgattttcga ttgactcttg caccattgcc atctctgcca gacttaatag
     1261 caatacaatc atcaccacag gccaaatcac attcatagac acgcacattt gttgaagaat
     1321 caatatcaat cccatctgta cttggtccat cattgttgcg gatgattact ttttctacta
     1381 atacatcgtt agaataagtg atttgcaagt tccaaaaacc tgatttctga aaaatcaaat
     1441 cacgaacaac aacatgttct gcatgataca gtaaacaagc gcgtggacgt ttaatagcat
     1501 aatccgcaat ccaacgaagt cccttttgat cgtattcagc tcttgtcccg cttttttgat
     1561 cttttcccca atacagctcc caccaatggt ctccttgacc gtcgattatt ccttttcctt
     1621 ctataagaat atctttcgcc gagagaacat tcaaaatcgc tgctggccat ttcatttcta
     1681 cgccggctac tcgtgtatcg atttctggaa atgcttcgat atctgttctc cccttgagga
     1741 ctgcaccttc ttcaaagata agatgactct tatcttttaa aaaaagggct ccgactaaat
     1801 aaatgccttt tggaataaat acaggtaagt gttctttcgc accttgatcg attgcttttt
     1861 gcagtattat tgtatcatct tgttgagtgt cgtttgtttt aaagttcaaa gcattgataa
     1921 tccctttttt tgtccgcaat acgtttctcc ctatctttca ttgatttttt tcaattcttc
     1981 accaataaat acagtttttg aacgattcag tgggtaacct actagcaaaa tgattgcgga
     2041 tacaaataag cagaatgctg gtaacaagtt tgccatcgta taaatccttt cttgtactaa
     2101 aactgattgg atggctccac ctgttgtaga cgattggtaa ccaatgagtg ccagcataaa
     2161 tccgcctacc gctcctgcac atgcttgtcc tacttttctc gcaaaagaat ttactccata
     2221 tactgttcca tcttctctta agcctgtctt atattgatga taatcaatca cgtcagtaat
     2281 gaatgcccag accatcaaat tgaataaacc agatcctaaa gtagcgataa ataaaagaat
     2341 cagatatacc catgcatttg ttatatgaag gaaatacatc agcaagtaca tacatgaaga
     2401 agcaagtaac gcaaatacgc ttgcttcctt tttaccaaat aattttgtca gctttgtagc
     2461 aaatggtgct aaaactacta ctgttccgta agtaaataaa agagcaacag acattgcttg
     2521 tttattatgg aagtaatcat tgaataaata agtcatattc gtcccagcta aaatctgatt
     2581 gatcacaatg aaaatgtcaa caatgactaa aataatcagt gctcgattag ctaacaaacc
     2641 ttttaccaac tgagaagcag atactttttc gtttttgaca actcttactc tttcagtagt
     2701 caatttacaa gttaacatat atgcgacaaa tgctattgca gcacatccga ttgaaatcca
     2761 aaagaaatga ttccctgaaa cgacttgttg tccactcttg ttatgggtat acattaaaat
     2821 cggaatgaag aatcctgtag ttgatccgcc aatcgcagaa ccaatgcttc ggaacgtgga
     2881 caacgaggtg cggtcattag gatttgagct aattgctgct gccattgctc catacgggat
     2941 attgattgtt gagagaaaaa tcccataaac aatgtatgaa acaaaaatat aagcaatctt
     3001 caccgtcatt ggaagatgtt ggacgaatgg caaaaacaaa atgacagtca ctaagcaaaa
     3061 tggatacttc atttttctga tccaaggaat aaatcggcca gtttctgtta actctgagac
     3121 atcacataat cttccaacca tcacatcagc aaacgcatcc aaaattctcg aaatcaagaa
     3181 taacgtacct acgattgccc ctgaaacgcc aagaacattc gtataataaa tcatcaagaa
     3241 actattgact aaacctaaaa taaaacagtt acctagatca ccgaacatgt agcctatctt
     3301 atcggaaatc ccaaattcct ttttttcttt ttttattgta tttgctgtaa cagcattttg
     3361 tgaaagcatt tgaattcctc ctacctcttc tagtaaacgt tttcaaaatt ataactcttt
     3421 ttttcttgtt tttatattca caatgttggc tttttattgc attatcttga cagataaaaa
     3481 acaaaaaata atctaaaaac attgatgcat aagattgata acttttttta cataacaata
     3541 tatacaaaca aaaaaattca ctaactagtg aaaataagtt agtgaacctc atttattaaa
     3601 gaattaaatt acagatgatc ttttccatca tacttgaaaa actcaaaatc agcataactt
     3661 cctctttttt tatttagatc atgcactgct atcccgataa aatttccagt aaaccctcct
     3721 gagagtatac acatgttttt ttgcggacct actttcttcc attcttcagt tgatacgtct
     3781 ttcaaatgaa actgtgctgt ctctttcttt acagtgactt tcaaaaaagt cttcttttct
     3841 gtgagtggaa tcgtccaatc ttctatttgt gctactccgt tttctgattc tatcatacgt
     3901 aggcattttc ccttgtcctc attccaagta acataacaat aaatataatt ggattcattt
     3961 aagtacagta ccagtccagc catctgatta aaattattag gcatgtattc aaatgctgtc
     4021 tccgcatcaa aagtaaaatc cgtttgccga atagctaaca aatgatgttc gaaggtagat
     4081 tgaagagatt caccggaaat cagacgtaaa aaacctggtc tacattttgt atcacaccaa
     4141 tcagcatttg gcaaaatgcg tctggcattc cagttcttct ttagctctcc ttcaaatgta
     4201 tccataaact gatgatcttt ttcttgttgt acctcttcat ttgtctcaat cattatttct
     4261 tccatcggag ttgtctggct atctttaagt cttaaccaat cgtcggacgt ccaatacact
     4321 tcttgaatag cggtttctct tcccaaaata gccgcaccgt ttaatggtct ggtacaaaga
     4381 tatgtcatgt accatcttcc tgacggggtt tgtactaagc tcccatgtcc tgtacattgc
     4441 aatgtagaag caggtttgtc actagctgtc agcataggaa aaccaggatc aagctcgtaa
     4501 ggaccagtaa tattctttgc tcggcaaact gtaactgaat gtcctcttcc tgtaccgcct
     4561 tctgccgtca tcaaataata atacccgtta cgaaaataca aatgtggtgc ctccgttttc
     4621 gctaattctg tacctgcaaa tattttatag atgggaccat caagcttctt cttctctgca
     4681 tcatattctt gtaatacgat accgctggat ttattcggtg tgtccagacg ataatcccat
     4741 agttcattga caagccattt ttttcccgtt tcaagatcat ggaacaaaga aggatcaaag
     4801 ccgttactat ttaaataaat tggttcggac caaggacctg tgatctcaga tgcagtgatc
     4861 aaataattgt ggacatcttt aaacggacgg cctgcacttt tgacatctgt gtaaacaaga
     4921 taaaacaatc catcagcata actgatctgt ggcgcccata tacttccatt tgtaggattt
     4981 ccttgcaaag atacttgagt ggtcaaaata tccgttgtat gtgaccagtt gactaaattt
     5041 ttcgactcat atactcggat tcctggaagc cattcaaaag aggagacaat aatgtaatac
     5101 cgctctttca ctcttaatat attaggatct ggattgaatc ctcttaaaat aggatttttc
     5161 actttgatag tctgcatgat tcaggctcct tttctcattc ttactcgata taaactgaat
     5221 gccccagctg cgaaataaaa aaatgcaaaa ggaaacgcaa taaactgagt gccaatcaac
     5281 aatatgaatc ctgttataaa atacaaacca gtggcagttg ttaagtattt tcctttagca
     5341 gtcaaaaaca atgctactgc taaaaaagca agtgaaataa acaacacaac ggcaaacaga
     5401 ccagtcatgt cctgtaataa tccaaatgta ttttctaaag acaaagttga atgatctaca
     5461 gcaagcgact gataactttt tttaaactct gacgcagaca tattacttaa agtaactgct
     5521 aacccgccaa agaaaatcaa agatagactg ccaccgacca ttcctagcaa tagttcccat
     5581 tttcttttca tttctgaacc ccctgctttt ctaaatgtat ccattcaggt cttttgatcg
     5641 atgtttcata attgttatta cgttcagaga atttgacagt ctgttcattt ttcttgtcat
     5701 cccaattatc ccaaccagtt gggtgaacat gcccacctat cttacacgct tcaaataaga
     5761 catttgcata cggacgccac ggtcttccta aatagacgtt tctagtatca ggttctgcag
     5821 tcaaggtaca gctttcaaaa cgataccctg ttttttgatt tttcggcgta gatgctgctg
     5881 tgatgtatcc aggattttta ctggctaagc tatggatatg acactgatga aaaacggcat
     5941 ctgccccacc aaatatgaaa tccaccgttc cttcaatcca gcaatattca taggtctgac
     6001 gacaatactc aggattggca gaagccggtg tacaaaaagg agtaccatct ttttgcaaat
     6061 caggcaacgg acccgtgcat aaggtatcct gataaccaga tagtcgacag ttttttaaag
     6121 atacgcgatc tcctgaattg aataaagcaa cagcctgtcc taccttttct cctggacctg
     6181 ctgtattttc gatgtgaaga ttttctaata cgacattcga tccttctaag aaaaaagtag
     6241 cacttcggaa agtccctaac tggctaccgt caagatactc ctgttttgca aaacgattac
     6301 cggagataac tactgttcct gctcccacaa gtttaaaatt ggataatctg ctttctatat
     6361 attcatcata tcttccttct tttactatca agacctttgg atggctatcc ggcaggcctg
     6421 ccaaataatc gattccttct tggatagttt caaaatccgt cggggtatct atagcattct
     6481 ttccaattat cagtttgtct ttcatcctca taaatgctcc cttatgaatt gtttccaaat
     6541 atttctcatt tcttgtgttt ccatatgacc gcctgttaaa gaaaaagaag aaaagttttc
     6601 tggactaccc attgattgat actttttgtc cagccctttt ctcagcttca gtacgccttc
     6661 gtccaagcac atcgtatcgt tttttccaac taagctaaga cgagggcgcg gagcgatttt
     6721 ttcttggatt gctaacgttg tataagctgt caatagattt ggcacatagt aataaaaccc
     6781 atgatgatct aggcggcgat gtagcaaaag tatttcgatg tccacctgtg ccgctagatc
     6841 aatacaaact ttgacacgag aatccaatgc tgtcacccac cagcttaata agcctcccat
     6901 agaaagacca atcgttgcga gccgttgagt atctgtgtct tcccttgtct ccaaataatc
     6961 gatcaagctg atcacatcat aaatacgcat tccccataac gtttttcctg ttaataaaaa
     7021 ttgtttgaac aactcgcttt cagaaatacc tccgcgttct tcaaatcccc aagcatcaat
     7081 cgaccaaaca gcatatccca ttcctgtcag tacttctgca aaagatggag aagctaagta
     7141 aggagcacca tggatcaatt cacttttccc gactgaaaaa tctccgccgt gagaatgcag
     7201 gtaaaggacc ggcggaaacg gtccttcttt ttctggataa gcatagaggg ctggtactgt
     7261 ttccaattca tttaagtaca attgatagta ttcaagcata aaaccgtttt gtttttctcg
     7321 gtataatcgt tttccactag gggtatgtct gctagatgga gcacctaaaa aatcattcaa
     7381 ctgcataagc aaagttttta cgaacaacca gttcatccat attttctgat tgatttgatt
     7441 ggaatttctc aatactgatt tctttagtat tttctaatag aaatgctggt ccctcgtgat
     7501 tttcaatcga catctggtta aaggaaacct tacccgcaaa gccaatataa aatccttgtc
     7561 tgctcatttc ctctattcct gtcatcatag caggaacacc gggaactgca tcttgggcca
     7621 tcgagacatc gatattgtca aatgtgattt cttgtatgaa ttgttccgct aatccataaa
     7681 taaaacctgc agaagcatgg acattccttg ccgtgatatt cgaaaaatgg atccttctga
     7741 atgctggtgt ccgttcatct atcggataag cctttttttc ccatacatac ggttctttcc
     7801 ctcgcggacc acagaaataa taaagattca gtataaatgg acacatcaca ttatccatga
     7861 ctatattgga tactcgaata tcttcaacga tcccgcctcg acctcgtcta gatttcaatc
     7921 gtattcctcg atcagtttct tggaagatac aatttgaaat ggtaatatta cgaatactac
     7981 cactcatttc acttcctaat acgacaccgc catgtccatg gaccatcgtg caatttgtga
     8041 tcgtgatatt ttcgcaagcg atcctttcgt acgtatcttc agtccctgcc ttgattgcaa
     8101 tacagtcatc tcccacgtca atatggcaat tactaatacg cacatttttg catgattctg
     8161 gatcaattcc gtctgtattt ggtgaatccg ctgggttcaa gatcgtcaag ttatcaaacg
     8221 ttgcattact gcaaagaatc gggttgatcg tccaacttgg tgactggatc aatttaatat
     8281 ctttcacagt aattcgatga cagttatgga aactcatcaa tttaggacga ggataagcga
     8341 gattatctgg ttcatttcta aaagtatgcc accatttttt tccatttcca tctaatgtac
     8401 cgaaaccagt gacagagatg ttctctacat tttgagcata gatacaggaa gcataaactt
     8461 ttcgatggac tccttcccaa cgtgaatgaa caacaggata atcttttgga tcgtcagaga
     8521 atttcagaac cgctcctgcg cttaaatgaa gttcgacatt gctttttaaa aataaagctc
     8581 ctgttagaaa ttcacctgct ggaacaacta cggtcccgcc tccgtcactt gctgcagcat
     8641 caatggcttg ttgtattgct tcagtattca attcatcaat tgatgcgcca aatgtcaaaa
     8701 tatcatacat atttataatg cctccacttc aatcaatgct tgcaagaatg caccaacgcc
     8761 tttttgatca ttacaaataa ttggttcact gatgtagtaa gcatatgaac catctcgctg
     8821 atctgctccg cctaaccctg ctacttgaca gtttttattc aagttcagcc agccttcttt
     8881 tgtttccaga acaaattcat caagtaatcc ttgatgtgat ttcttcactt gtggaagcca
     8941 ttcttctttg ttcagcagtc ccaaacgtat tcctttagcc attgcgtaaa caaacatact
     9001 actgccggaa gcttccagat aatttccttt ccgttttgtt tctgttgtta cttgatacca
     9061 tgtcccgctg ttttcttctt gatatggaag taatgcagcc agtgtctttt ctagaatttc
     9121 tttcagcaaa gaacaatctg tttcttcatg aagtaattca taggtatctg ctgcagccat
     9181 caaataccag ccaatcgatc ggctccaaaa atgatgggat agacctgttt ttggatcagc
     9241 ccatggttgg accttctttt catcccatgc atgaatcagc aaatttgttt ttggatcgaa
     9301 tagatgttta taactgattt caaactgtct caaaacatct tggtaatctt tttcttcact
     9361 aaaattctgg ataaattcag cataaaaagg agaacccata tataagccat ccaaccaaat
     9421 ttgataagga taaatttctt tatgccaaaa agctccttcg gatgtgcgtg gatggtttgc
     9481 caactgctgg gaaaggagtt ctgctgcttt tttatatttt tcttcgcctg tttctttgta
     9541 caataaaaag aaaagctttc ctgtatttac atggtcgata ttgtattctt caacgctgta
     9601 gccacggatc gttccatctt cttgcacgaa atagtcgata ttgtctttta tgaaatcaaa
     9661 ataaattttt tcttgggttc gttcccaaag taattggaac cctttaagta cgacgccata
     9721 gtcataagac cattttcctt tataccactt ttcttcatat aagcgaggtg ttctttccat
     9781 gatacttttt gctaatttct ttgaccagtt ttccattatt tgctctcctt taaaaattaa
     9841 aataggattt gggacaaata ccaagaagta tttgtcccaa tcgtctatat tactgtgccg
     9901 ctgctttgta tgcttcctcg tactcttgtg tgattcgatc gcctccttgt gctttccagt
     9961 cttctacagc ttttttgaat ccatcttcgt caagctgtcc catgatgtat tgcaccgtag
    10021 catcaatgac gattttttca atttctgatc ctacttcatt gttcgtcggt gaatccaatg
    10081 gcacagaagg atccattaca gcaaattctt cattttcttt gatcaattga ttagagaatt
    10141 ctttttcagg gtctgtatct ttgaaagaga acgtcacttc actaggacga gagcttgata
    10201 acggttgcac ctcttgttgc caaagatcca tatcgataaa ttcgatagaa ccatcatcat
    10261 tcaattcata atgcgttcct tcgataccgc cagtcatcaa tttatacaca tcttcttcta
    10321 aaagatcatc aacaaattga agtaatttct tcaattgtgc ttcgtctttt acttgagatt
    10381 tgggaaatgc tagcaagccg ccaataccat ttccttctga ccaaacatga taaccgccgc
    10441 cttcaccatc tgagatcttg tttacaggca ctaattccat atcatcttga ataccttgac
    10501 ccatcgtctt cagattcttg atatccacca ttccagtgta gattccagtt cttccttgtg
    10561 caaattgttc ttgctgatca gtcttttggg taactgcaaa gtcttgtgcc aaatagccat
    10621 tctcaaatag atctcttgaa aaattcaaag ctttcatata ctcttctgta tcaaattctg
    10681 gagtgaattt gccattatcg tctacagccc agccatttgg tgctccaaaa taagaagtga
    10741 aaagtttaaa gctggtataa cgaatatcac taggcgcacg atcgccaaaa ccaactgtgt
    10801 cgtccacacc atttccatca ggatcgtttt ctgtaaattg tttagctact tcataaagct
    10861 catccatggt agttggaaca tctagtccta gattatccaa ccagtctttt cgaatgacta
    10921 agccagcacg agcgtagtct ttttgtatcg gtacgccgta caaggcaccg tcgatactcg
    10981 cagcttcgat tctatcttca gaaatttgac ttaaattttt atagtctttt aaatattctg
    11041 atacatccca gaatacgcct gattttaacg cattgcggac agaagagttt ttcaacatcg
    11101 caatttgaag tgtaacgata tctcctagtt catcagaagc caatgcagtt gttaatcttt
    11161 cttcttttga agcatcagga atccagttga atgtcagttc cgtatcggtt ttttcttcga
    11221 tcaagttcac aatcgtgtct gtaggcggtg aagcatgatg caaaatattt aaccaagtga
    11281 ttttagcttt tccatcttct gtctctgaag aactgttact tgaactgctg ccgcatgcgg
    11341 caagtgctag aattcctgca aaactaagac ctaattttac gagcgttgct tttttcataa
    11401 attttctcct tcactgtttt aataatattt ttgttttctt ctgttttttc tgtatatgag
    11461 ttcttccatt ccaaatggca aaatatagaa tttgctgtcc acgtgactgc ggaaaagaag
    11521 agactgccac cgataaaggt taaaacacct ggcattgttt ggatgatcat cagataaatc
    11581 cctaccatac ttaatatcaa cactaatgag taatgaagat gtgagaatcc gaataaaaat
    11641 gccattttca ttttgaaaaa atatcctttc caatcataat gagccatgat tgggaaaata
    11701 tagagtgctg agagcacata tatgaacgca gcaatataca aagcgatcct aagataccaa
    11761 ttgtgtatga aagaaagatc cacaagtaaa acaatcccga tggcgccata tatccagctc
    11821 atcagcaagg tttcacgata gttttcttta aaatatgtga agtacgtttt cgtcaaagga
    11881 aacgtttctt ttgagcgcag ccattttcta atcactgcaa ccatcgcata cgatgcagga
    11941 ccgaaagtaa aaactcccaa acctgcgatg actaaaccgc cccacagaaa attcaaataa
    12001 accaactgta aaatacgatt tagccttccg tttattttat ctaatgactg cagcatatct
    12061 ttccctctct ttctatctta gtaaacgccg tcttctccta gctttttggc aatcttatta
    12121 gctaaaatta ccataaacaa tcctacgacc cctttaaaca atcccattgc tgtactgaaa
    12181 cttaactgtc cattcttcaa tccagctgta taaatatagg tgtcgaaaat ttctgcaacg
    12241 cttcgattca atgaattcaa taacaagtac atatgctcga accctaagtc taatgtctga
    12301 ccgattttta gaatcagcaa ggtaatgatt actggacgaa ttgccggcaa tgtaacatgc
    12361 catgttttgc gtaagcgtcc tgctccatcc atttctgcag cttcatacaa ctgtgtatcg
    12421 actgcagtta tcgctgaaag gtagatgatc gtagaccagc ccaactcttt ccagatcact
    12481 tgtccgatat atactgtgcg tgtccattca ggggatgtta gaaaactgat tttttcaaat
    12541 cccattgttg caaggaattc attcaatacc cctccgtcaa cattcaaaaa tacataagta
    12601 atcgaaacaa tgattaccca agacatgaag tgagggatgt aaatgatcgt ttgaatcccg
    12661 tttttcaatc gtttgttcgt tacttcattt aatagtaaag acaaaatgat tggcatcgga
    12721 aaaaacacga agatatttaa tccgaacaag atcaacgtat ttcttaataa tgtaaagaat
    12781 gtcggttctg taaacaaacg aatgaaatgt ttgaaaccga cccaaggact tcccattatt
    12841 cctaaaaatg gttgataatc ttgaaaagca ataacgagtc cccccatagg aagataccta
    12901 aaaatcaaga aataaaggac tcccggcaga atcatcacat ataaaaattt attcgttttg
    12961 attcctgcaa ttattttttt tcgtcttctg agcttttctt cttttttcga tagcgtcagt
    13021 tgaaatggtt cttgtttctt tacactttcc ataagcccct ccttagtttt gtgaatgttt
    13081 gctgcttatg acttcatgat agataactat ctgaattacg tatataatca tttttaccgt
    13141 aagtaaaaac gcttacatag caatgatttt tgtgctatac aaaacgataa agtgtatttt
    13201 ttcacaaata aactacgcat agcaaacctt ctattttttt ctatctgaca cttagcatag
    13261 gaaatgatta tatacgtaat ctttcaccga tgataaattg aacatataga aacagaaaca
    13321 tttaatttat tttgaggagg agcctatcta tatgaaaaag aaagtctcta taggagaaag
    13381 aagttttaca cttttcaaca atacgtttct aattttgcta gctttgatct gtatcgttcc
    13441 ttttttaaat atcatcgcta catcttttgc ttctacacaa gaagtcgtcg cgaaaaagtt
    13501 tatccttttt cctactacct tttctttaga cgcgtatcgc tacattcttt ctacgccgac
    13561 catttttaga gcacttgctg tttcgattgg tgttacaggt gtcggaacga tcgtcagtat
    13621 gtgtgcaact tcactgatgg cctacggtct ttccagaaag tatttgtttg gtcgaggttt
    13681 cgtcaacttt cttgttgtat tttctatgtt gttcagcggg gggatgattc caacgttctt
    13741 agttgttcgt tctctagggc tggtcaattc ttactgggcc atgatcctgc ctgtggctgt
    13801 taatgcaatg aatatgatca ttatgagaaa ctttttccaa gccttgccgg atagtttgga
    13861 agaatcagca aaaatggatg gttgcacaga ttttggtgta tttttcaaaa ttatgctgcc
    13921 attagcgtta ccgtctattg ctactatctc gcttttttat gctgttactt actggaacac
    13981 ttatatgact gctattttgt atatcaacga ttcatctaaa tggccgatac agattctttt
    14041 acgccaaatc gtcattgtat caagtgggat gcaagcagaa agtagtgccg ttgatgtgat
    14101 tccaccagca caaacagtta aaatggctgt tatcgttatt gcaacagtgc ctatgctgat
    14161 tgtttatcct tttgttcaga aatattttgt caaaggagca ctcgtaggtt ctgtcaaagg
    14221 gtgattatgt actgaacgca aaatggtagt tgtgtcagaa gtggtcagct tcaagaaata
    14281 agaaggcatt tacgaaaatt gcttcttaaa tttttgtgaa atttcggctt atttttcgaa
    14341 gaatctactc ctggaacacc gtgtatcaga ggttgtgaaa gagacgttca gccttgagcg
    14401 atgataaaaa ctctcacaaa cattgcgacg agtaacccac aggagcaata agaagcgatt
    14461 ttgaaaaata gcttcccata tttcacaaaa ttatgcctta ttgtcgatag cctgtctctt
    14521 gaacgccatt tattcgtaaa aaagaactgt gacaagactt ttgtcacagt tctttttgcg
    14581 tgcttagcct tgaaatttaa ctatccataa atacaaatac tagggttatt ctaacttctt
    14641 ttattgcttg aatcagtcca caagaaaaac agcctcttga ttcacaaata tttttttcga
    14701 tattctcccg gcgtaatcga ttccttcttt ttaaagaaac gaataaaatt ttgcggattt
    14761 cgatattgca atctttctgc aatctctttt acggagaggt tagtctcttt caaccatttt
    14821 tttgctacct ctaaacgatg attttgaaca aaatcaccaa atttttctcc tgtttccttt
    14881 ttaaatacat tacttaaata gttagggtta taatgcaacc tatcagcgat cacatctaaa
    14941 gacagatcac gatcatattc tgtgtagacg atatgcataa tattctccga caaattttta
    15001 aattcatgat cagtgattgc ttgagagcat tctgtgattg gcagaactaa ttgttctaaa
    15061 acaagttttt ctagttcttt gggatgataa ttgttcagtg cttttacata aatttgtttc
    15121 atgttatcaa agttttttga atctactccc aataactgtc ctaattgaac gagttcattg
    15181 atcaagcgga ccgaaactac ttcccgactc aaaggatttt tattttgtgc aaacaatgca
    15241 tcaatcaatt catgtactaa attcttcact tcctgatttc cagaacgaat ggcttcaaac
    15301 aatcgatttt gttcttctat cggatatcta ataagtgttt tttcatgagc agcaggaacg
    15361 atttcctgat aaaaaataat tgaacttgga ccagtattta cacgataata cagggcttct
    15421 tttgcccgat caaccgattg cttgctttca ttcagcgttt cgaaccggtt actgatgcct
    15481 atactgatag ttaaattcaa gtattctttt acacgttttt gaatgagtcg gcaatactcc
    15541 atgacttttt tgcttgcttc tgcatcatct ttatccattc gataaatagt ggcttgcatt
    15601 tcttcattca aaacgatcgg cagcattcga ttttcctttg gcacaatttc cgtgatcatg
    15661 ttgttgatcg ctaaaagtag caaatcacgc tccccaccgt gactatcttc taacagatcg
    15721 atttgaacca aagctgtata atagcagtca ttttgagaac tataaccaaa ttgctgcaac
    15781 cgctgatcta gttctcgcct ttctactcga tttctaaata aactaagtac aaatagcgtt
    15841 tccagctgtg gcttttgggt aactaagtgt gcacttaacg cttctttttc tcctatgatc
    15901 cgactgactg attgagcgac caaatctagt tctttcccac tgaatccttt tgatttaaga
    15961 ttcagacgtt cctgtatttg agaaatcgga cgggcaaatc tgtccgaaaa taagtaggaa
    16021 agaagaccaa tgagtcctac cagtgttaaa gacactgcaa ctagcccgat tctcagattg
    16081 cggatcattg cgccaattgc actagagtca acttctaatc tgtaaatcca attattataa
    16141 tctgatttca gtactatata cgttttatct ttttctctta tcactttcag ctgattgtaa
    16201 tctagatcca cgtccgttaa tacagttggt tgctctttat tttttactgt ctgagtagta
    16261 aaaaggttgc caacttcgtt ttcaatagaa agtatgtctt ctccactttc accaacaact
    16321 tgttctattg tatgtttctc tatcgtagca attcccaatg catatttttc tttttcaaac
    16381 attggcaaag aaatcaccat ttcgattcct ttgtttttct tttgccaaaa taaattattt
    16441 ttgttattta tgtacttctg ttgatacttt tcaatttcct cttcggtcag ttgactcaac
    16501 gatccattga ttactcccca tttaccagcc aaactgacta aatcataatt attatcatcc
    16561 ataacaatcg tttctataaa atttagttct ttcctgattt cagaataagt ggagtaatct
    16621 gtatatgtca gcggatgctt gaatatgtcc gagaaatttt tggtcgaacc atacgtagaa
    16681 aacgaatatt caatcgttct aattttccat tcaacgttag ttttaacttg cctgagcaaa
    16741 ttctttttgt ctgttaaata actcgattcg atcgattcat aggtattctg gtaaatgaat
    16801 aaactaaatc ctatgacaag tacggctcct aataaaaaca tcggtaaaaa tattttataa
    16861 aatactgtac ttttcttcat tttcttcctc tcctcctttt aaaataaaag gctttcattt
    16921 ttctgtaaaa ttgatactca tctaattaaa tgagcattcc ccgctttcaa gaatagcata
    16981 attaaaaata aaaatccaag taatttttaa cgtgtgcaat cttttcatat caaagatcta
    17041 ttgacttatc gtagttatcg taatatgatg aatgcgttaa caaaaagtga aaaagtaagg
    17101 aaaatgatgg aatggtaacg atcaaagatg tcgctaaagc agctggcgtt tctcatacga
    17161 cagtttctcg tgctttgaat aacagcagtt taataaaaaa tgaaacaaaa caaaaaatac
    17221 gacaactagc taaggaaatg aattattcgc caaactatag tgcaaaaggt ttagtgaatc
    17281 aaaaaaaata tctaatcgga ctatttttct caagtttgca taaaggaact tcatcaaatt
    17341 tcctagcaga ttccattgca ggcatccatt cagtattaga cacaaattac agtttatctg
    17401 ttgaaagtat cgatgttgtt gatttaacag aaatcaacct gcaacgctac gatggactga
    17461 tcgttatgag tcaaagtgat gatgatcagc ctttcatcga ctatctcaaa gaaaaagaat
    17521 ttcctttcgt tgttgtcaat cgtcacatca atgatccagc ggttatcaac gtcactgccg
    17581 atgatgcggc cggtgttatg caggcagtag attacggtat tggatgcgga catacgaaga
    17641 tcgcttatat tggcggaaag aaaaattttc gttcgacaaa agaacgggaa aaaggggtat
    17701 tgaaaagtct aaaaaaagcg agcatccctg tcaatccagc ctatttttta acaggagatt
    17761 acagcttaga aagcggcctc caaaacatgg aatacctatt atcactttct gacctgccta
    17821 ctctggtttt ttgcggcaac gacgacatag cgattggtgc attgagagct gtacatttag
    17881 ctggcctccg tgttccccag aacatttctc tgatcgggtt cgatgattct ccagtcgtct
    17941 cctatctcaa tccgccgctt accaccgtac gtaagccttt gaaagaaatg tgtcaagaag
    18001 gaacaaagct tttactagat ttgatcgaag gcaggacgat cgaacaatct aaaattgagc
    18061 tctccacctt gttgatcctt cgtgagtcga tcaattactt gtaaactaca agtaatttta
    18121 tataaaaatg ttaacgtgtg cataacacag aaaggaagtt tatatgaaaa aactgacaaa
    18181 agaattagtg aaaaaaaacg aagcacctgt aaaagttctt cagtttggtg aaggcaattt
    18241 tatgcgtgga tttattgatt ggcagattca gcagctgaat aaccaacaat tgtttaaagg
    18301 taatgttgca atcattcaac ctttagaaca aggtcttgga aatatgatga accagcaaga
    18361 taatttatat acggtcattt tacaaggact cagcaatggc gaaatcgttg atacttccga
    18421 gattatcacc gtagtagaac aaatgatcaa tccttatgat gaatgggatg cttatctatc
    18481 tctagcagaa aatgacgact tggcctatat cgtctccaat acaacagagg caggaatcca
    18541 attcgtggag actgataatt taacagatac tcccccacag agcctcccgg gcaaactgac
    18601 agccttttta taccgacgtt tcaaattaaa caaagctggc tttaccatca ttccttgcga
    18661 actgattgac agaaacggcg aacgtctaaa agaaatcatt ttacgctacg cagaaaaatg
    18721 ggatttagaa cctgcttttg ttgagtggtt agaaaaagaa aatgttttct gttgtagttt
    18781 agttgatcgc atcgtcccag gttatcctcg cgaagatgca ggtgttttca atcaacggca
    18841 taactatgaa gatcaattga tggtcaaagc agaaccattc atgctttggg tgatcgaagg
    18901 gcctaaagaa ttggagaatc aactaccatt caaacaggct ggcttgaatg tcatcatcac
    18961 agatgatatg actccttatc gtgaacgtaa ggtgcatttg cttaatggac cgcatacagc
    19021 gatggtccct cttgctttgt tggcggaatt ggaaactgta gaagaagtaa tgaaagatcc
    19081 tttattctcc gcatatgttg atcagttatt caatctagaa ttgattccta tgctttcttt
    19141 acctaaagat gaattagcca tttatgctga ccaaatcaaa gaacgtttct tgaatccttt
    19201 tgcccatcac aaattagaag cgatttcatt aaatagtgtt tcaaagttca gcacccgtct
    19261 gcttccagtg ttcaagaagt atatcgaaga acaaaatcag gtaccaccgt taatcactgt
    19321 ttcactagct gcgctacttc ttatgtatcg aggcgatcaa gtaaagccac atgatgatga
    19381 aaagacgata agcgaattta ctgatgcttg gtctgataat ggaacagcta ttcctcgatt
    19441 attgcaaaac gctgcgcttt ggggagaaga tttgtctcaa ataccgaatg tgacagatac
    19501 agttcaagaa atagctgcaa agatcgatca aaaaggtgtc cggtcagtat tacaagaaat
    19561 gaaaggaacg atggtccatg cttgaaaccc tgcaaccaac aatgaaatta aatcgacgag
    19621 acagtgtggt cgtcgcatta acccctattc caaaacaaac acaactgacg attgatcagc
    19681 aaacgatcac cactcttgaa gatatcccgc aaggtcataa gattgcattg ggtgatttga
    19741 aagctggaga caacgtgatc aaatatggct atccaatcgg tcatgtgacg acagacgtaa
    19801 ctgccggtca atggctgcac actcataatg taaaaaccaa tctttctggt gaattggatt
    19861 atcgatatga aaaagatgtc catccaagtc attacctttt tgagaaccga acatttcaag
    19921 gttacttgcg aaaaaatgga aaagtaggga ttcgtaatga tttgttttta gtacctaccg
    19981 ttgggtgtgt gaatggcatt gctgaactga tcgtcaaaca gttcaaggaa aaacatccag
    20041 atctgggaca gtttgaccat attacgattt taaagcatcc ttatggctgt tcgcagcttg
    20101 gaaaagatca tcaaaatact cgagaaattt tagcggacgc agtaaatcat cccaatgccg
    20161 gaggagtttt agtatttgga ttaggttgtg agaacaatac agttcctgaa ttcaaaaaaa
    20221 ttttaggtga atatgatgaa gaacgagtga aatttctagt ggctcaagat gtttacgatg
    20281 agatcgaaca aggtgtggct ctattagaag agcttttaac agcggcggaa aatgaccagc
    20341 gcatatcagt cccgctctct aagttgaatg tcggtttgaa atgcggcggt tctgatggtc
    20401 tatcgggaat aactgctaat cctttacttg gtgcattttc tgactacttg attgctcaag
    20461 gaggcagcac gatcttaaca gaagtgccag aaatgtttgg cgcagaacaa gtattgatgg
    20521 cacgagcgga aaatgaagaa gtttttgact caatcgttga cttgatcaat gacttcaaac
    20581 agtatttctt gtcttacggg gaaccagttt acgaaaaccc atctcctggt aataaagcag
    20641 gtgggatcac tacattagaa gataagtctt taggctgcac gcaaaaatca ggaagctctc
    20701 ctgtcgttga tgtgctacaa tatggcgaaa aaatcagaaa accagggctt agtttattgc
    20761 aagctcccgg gaatgatctt gtagctgcct ctgctcttgc ttcatccgat tgccagttgg
    20821 tcttgtttac cacaggaaga gggactccgt ttggctcata tgtcccaacg gtcaaggtat
    20881 ctacgaatac aactcttttt gaacgcaaag gtcattggat ggattttaat gcaggcgtct
    20941 tattagaaca accaatggaa gtaatcttag aatcgtttgt tcaaaaaatc atcgctgtag
    21001 ctagtggaga agaaacgaaa aatgaacaaa atgacgttcg agaaattgcc atttttaaaa
    21061 acggagtaac actttgattt tcataaaaca gtataaaaag aaagaaggaa gatttatgtt
    21121 tttatctgat gattttttat taaaagacga ttgggcgaaa aagctttacc attcctacgc
    21181 aaaaaacatg cccattattg attatcactg tcacttagat ccaaaagaaa tttacgaaaa
    21241 caacaatttc agcaatctga cagaagcttg gttaggaggc gatcattaca aatggcgctt
    21301 gatgcgagct tgcggcgtgc ctgaagaaaa aatcacagga aatgcttctg attttgaaaa
    21361 atttttagct tggtgtcaaa ccgtaccaaa aattatcgga aatccgcttt acagttggtc
    21421 acatcttgaa ttgaagcgtt tcttcggtat tgacttgttg ataaatgaag aaaatgcaga
    21481 gaaaatttgg acacaagcaa atgaaatttt ggcagctcct gattttcgcc gtcgggaaat
    21541 cgcaaaaaaa tcgaatgtag aagtgatttg tacaacagat gatcccgcag acgacttgca
    21601 ctatcatcag ttgcttgctc atgaagaacc agatttgaag gttctacctt cattccgtcc
    21661 agataaagca ctcaatattg aaaaagaagg atttaatgca tgggtcacac tactggaaga
    21721 agcagctgac caaacgatca ccacctatca agaactgata gaagtcttag ggcagcggat
    21781 agaatacttc catcaacatg gatgtcgtgt ttccgaccac gctttagaca tcttacgcta
    21841 taaagaagcg gatgaaacag tattagaaga gatttttcaa aaagcacgag ctaacaaact
    21901 attatcttca gatgaaatcg atgcttatcg tacagaaaca ctgatacatt tgacccactt
    21961 ctatcattct cataattgga cgatgcagct gcacatccat gcttatcgta actgtaatac
    22021 acaaatgttg gaaaaattag ggcccgatac cggctatgat ggaatgaatg atctttcttt
    22081 gactattcct ctgcaaaaat tattgaaccg tgcagaagaa acggatcagt tgccaaagac
    22141 gatcctttat tcattgaatc cgaatgacta tcctgcgatt ttagctttga tgggctgttt
    22201 ccaaaaagaa cagaatggaa aactgcagtt aggttctgga tggtggtaca acgatactcg
    22261 agctggtatg cgcgatcaat tgacacaatt tgctgatggt agtgctttgg ggaattttgt
    22321 cggcatgctg acagattcaa gaagtttcct gtcctacact agacatgaat atttccgtcg
    22381 tgttctttgt gaatttttag gcgaaatggt catgcgagga gaagcacctg aagatgaaca
    22441 acttttagga agtctagttc aagcgattag ttatacaaat gctaaaaatt actttggctt
    22501 ttttgcctaa ttgattaata gtaacagtaa cgaatcaaaa acaggatagt gaaataacgg
    22561 aatccgttta tccacgtttt agagaagaag acggaccaaa tttgctccgt cttcttctct
    22621 tgctgttctg cttcattgcc tataaacctt tatgaaagaa gagataacat gcctactatc
    22681 catattgccg gtgattctac tgcggcagaa aaagatgaaa acaagcgtcc cgagacaggt
    22741 tggggagaaa aaatctctgc ttatttttca cccgagatcc agatcaataa ccaagcaaag
    22801 aatggacgca gcaccaaatc atttatccag gaaggaaggt tagcccgtct agcttcacag
    22861 tttcagccga atgatttctt atttgtacaa tttggacata acgaccagaa aatccaagaa
    22921 gaaagaggta cgcttccctt cggtagctat ttaaaaaatc tgcagatatt ttttgaatgc
    22981 gcaaaaaaag cgaacgtcca aatggtctta ctgacatctg tgacgcgacg agattactta
    23041 gaaaacggaa cattgaatcc agatatactt ggagactatc caaaagcgat gcgtgcattt
    23101 gctgagaaac accatattcc tcttttagat gtgttctcaa gatcacaaga attgttccag
    23161 accttctcaa aagaagagac aaaaaaattc tacctgcatc ttatacctga tacttgtaaa
    23221 aattacccag aaggactaaa agacaatacc cactttagtc cagaaggcgc tgataaagtt
    23281 gcccgaataa ttgttgaatt gataaaagaa tcccgtctgc ctcttgctaa ttatttacaa
    23341 aaaggagttt gagatgtttc cattaaattt aggcatccgt gcccacgatt tagatgttcg
    23401 aaatcgtgaa gaaatcgttc aaaaagtatc acagcttcac ttgtcccata tccaatttgc
    23461 accacaaaaa gcatttcctg aacaacttaa attaactgac atgacacttg ggagtgctgc
    23521 ctattttggt gaatacttcc aaaaaaacaa tatcgaactt tccattttag gatgctatat
    23581 caacctatcc agcaaaaatc aagaagttcg tgcacaagca ttggcaactt tcaaacagca
    23641 aattgctctg tgctctgcct atcaagccaa gatgattgct acggaaaccg gtagtgtctc
    23701 tgtcggttac acaaaagaaa attttactga agaagcttat cagatcgcca gaaattctat
    23761 cattgaatta gtcgctcatg cagaaaattt tggcgtaact gttgctgttg aagcagggat
    23821 caatcatcca atctataact atcagttagc taaacgttta atcgatgaag tagcttcacc
    23881 aaatttaaaa atcattttag attgtgcgaa tttgatgcat aaagaaaatc atgctgatca
    23941 ggaaaaagtg atccgaggtg ccttggacaa tttacatggt tatattacag cgcttcatct
    24001 caaagactat atcatggaaa atggaaagat ccgcatggta cctgttggca agggctgttt
    24061 agatttccgc ccggtactgc attatatcaa atatgagcgt cctctaatgt acgccactct
    24121 tgaagctact cctgagattt atgttcctga agcaatagaa cacttgcagt ttatttacca
    24181 agattgttaa ggagaagatt atggaggaac gaatacagaa aagttatcaa aaatatcatg
    24241 caaatgcttt tcagacattg ctgcatcttt atcagggaaa ttattggcgt tttgccatgt
    24301 caggactctt ttttattatc aaacatcttc catcttggtt aatgccgatc gctattgcca
    24361 atgtaatcaa tgcagcttca tcgaaagatt cttctcagtt gcaggccatt tatttcaacg
    24421 cttttttgat ggcttgtctg attggtcaaa atatattgac gaattatttt catgtaaaat
    24481 accatagcac ttcgatccgt caagtagaag ctggactaag agcgaccctt atcaagaaaa
    24541 tccaagaact atctattcct tatcaaaaag aattgcaatc tggacgaatc cagtcaaaga
    24601 tcatccgtga tgtagaagct atccaaacgt tgtcctctca agtatttgtc agcggattaa
    24661 atatcgctgt caatttattc gtagctttag gtatcacgct ttataaaagt cctgttgttt
    24721 tcatgttttt cttattgact gttcctctcg ccgcattcgt tactctcttt ttccgtaaaa
    24781 ggatcagaca gtccaactca gacttcaggc aagaaatgga agagacttct gcaaaagtga
    24841 tcgaagtgat cgaattagca ccgattgctc gagctcatgg gttagaaaaa cacgaaacaa
    24901 ctcgcttaaa taagcatttt actcaaatct atgaaaaagg attccactta gatatcctgc
    24961 aatctgtttt cggatcagtc agctgggcta gttttcagat atttcagctg atttgtttga
    25021 ttttcactgg gatattagct ttacaagggc gcatccaacc cggcgatgtc gtgatgtatc
    25081 agacgtattt cacgacgatc gtcaattccg tttctggaat gatcacgctg attcctacga
    25141 tttcaaaagg catggaatct atcacttcta ttggcgaact gttgattgct ggcgatgtag
    25201 aaacttatca cggtaagaaa aaaatccaac atttggatgg aaattttcgt tttgaggatg
    25261 tttcttttct ttatccggac tcactcaaac cgattatcga tcatttttct ctagaggtga
    25321 aagctggaga aacaattgct tttgttgggc catctggctc tggaaaatct acactcctta
    25381 acttattgat tggatttatc cagccgactt caggaaaaat ttttctagat gatcagcctt
    25441 tggatgaact ggatatgcga agtgtgcgaa attatttagc cgttgttcct caaaccactt
    25501 tgttgttctc cgcttcgatc aaagagaaca tcacttatgg cttgaaaaac gtatcaaaag
    25561 aacgtttaga tgaagtcatc gaagctgcgc aactttcttc actgattgac cagcttcctg
    25621 atggtctgga taccttagta ggcgaacatg gcaacaagct gtctggtggc caaaagcaac
    25681 gtatctccat tgcacgagcg ttgatacgtc agccaaaaat cattttgcta gatgaagcaa
    25741 cctcagcttt agataaccag tcagagaaaa aaatccagca agccctgaat tacctgacag
    25801 aaacacccac tacttttatt gtggctcatc ggctttcaac gatcaaagag gcagataaaa
    25861 tcgttgtgat cgatgaagga aaaatcgttg aaataggtac ttacgaaaaa ctgttagctc
    25921 aaaaaggcta tttctaccgc ttgaaaaatg aatgacaaaa aataggagct atgacaagac
    25981 ttttgtcgta gctcctattt ctgaataaac ggtgttctcc tgccaactcc tcggtcacaa
    26041 gtcacaatag tcatcaaaca tgagaagctg ttttttgaaa ttgttccttg taactcagag
    26101 ttaaacggta ggctcacgac ctcttggtaa atggtgttca agagacagcc tatcggcaat
    26161 aagaagcaat tttgtcatcg ctcaaggccg aacgtctctt tcacaccctc tgttgtttca
    26221 taaaatagtt ttattcgctg taaaggtcgc gaactggtgt catgatgata cggttcaagt
    26281 cattgatgat tgtactgaag ccttgctctt tttgcatcaa gtcattgatt acttcttctg
    26341 attggatttt cacagccatt tcttgtgctt tcattgcatc ttcgtcgctg aactcttgtc
    26401 cactcatttg tttttcttgt aattcgattt gcatcgcttg gaagtctttg aacagtttgt
    26461 gtgcttcttc gtttgcttgt actttctcgt acgcttcttt caacgctttg aattctggta
    26521 attcacggat ctcacgttcg atttgattcg cgctatcgta gatgtttgac atgttatgcc
    26581 ctcttttctt ttagtagtta ctctctattg taacatgggg ttattcgttt tcaaaggggc
    26641 tactctcctt gatatttccg ccagaggtct ttagccgctt caccaattcc ctgaacgcct
    26701 tctttcacca tatcgccgaa gtttttcagc ccttcttttg cttgttcacc atattgattc
    26761 aagttatctt gccaatttcc agactctcca ttagaatttc ctgtgtttcc aacttgatct
    26821 gcagctacca cttgtcctcc tgtggcatag gcatctgcta cactaaatcc tgtttttgaa
    26881 gtatacggaa ggatgccttc tgccgctgat ttgaagactt tcccgacaac atttccactt
    26941 gtcccttcca aatagtgcag cttgctggat tcttcgtaac ccatccatgt cgaaatcact
    27001 acgtctggcg tgtaaccgat catccattgg tcatttgctt ttgtggcatc gaaattagtt
    27061 tctgtggttc ctgttttccc tgctatcgta taacctgcag gattcgcagc agccgctgtt
    27121 ccatttgaaa atgtaccaag aagcatgctg gtcatttcat cggctgtttc ctttgatatg
    27181 acctgttttg gttttttgtt tgtgttatcg acgatcaccg ctccagtcga atcaacgatt
    27241 ttcgtgataa gatgcggcgt atacatctga ccatcattgg caaatgcact gtaagcaccc
    27301 gccatgatca atggagatac tcctttttcc agtccaccaa gggctaagcc ataatactta
    27361 tcagattttg ctaaaggcag gccgaattct tctgctttat catatccttt ttgtaaaccg
    27421 atctcatgca aaagccatac agtaggcaaa ttcaaacttt gtgcaacagc ttgatacatc
    27481 ggtacttctc cttggtatgt cccgtcaaaa ttatgcgcat cgtaataact ttgcggttcg
    27541 tctttcaaga tactggaagg cttgtatcca gcttccagtg ctggtgtata tacgcttaat
    27601 ggtttgatcg ttgatcctgg tgaacgacgc atctgtgtag caaagctgaa tcctctaaag
    27661 acatgatctc ctcttcgtcc tactagtgct tgtacaccac ctgtattcgg atctaaagct
    27721 actgaagcag attggaccat ggcaccatct gaagcatttg ctgggaataa tgcactgttt
    27781 tgataagtag cttctaattg cttttgataa tcctgatcta aagctgtata gattttatag
    27841 cctttattca tgacatcttc ttcatcaaga ccatactcgt taactgcttc atcgatcact
    27901 gcatcaaaat aataaggata acgataacca gaatctgaat tatcgtatgt gtcattaaga
    27961 tacgcgctga tatctgtctg gctttctgct tgttcttgtt cttttgtgat ttttccgttt
    28021 tcttccatta cacttagtac tgtgtttttc cgatcattcg cattttttgg gtgatcgatc
    28081 ggattataaa taccaggacc tttcagcatt cctgccaaag tagcagcctc agacagcgta
    28141 acattcgttg catctactcc aaaatacttt ctggaagcgt cttggacacc ccataccccg
    28201 ttgccaaaat aggcattgtt aagatacatg gtcaagattt cttctttgct gtacttcttt
    28261 tcgatctcga ttgccaaaaa taattccttc gcttttcgat caaacgtttg gtctaatgtc
    28321 agatacgcat ttttggcaag ctgctgagtg atcgtacttc ctccgccccc tgatgttccg
    28381 ccagacaaga ccattcggac tgctgcacgg gcaatccctt tgatatcaaa cccgtgatgc
    28441 tcgtaaaaat tcctatcttc tgtcgagatt actgcatctt ggatataggg agaaatcgcg
    28501 tttaattcta catatgttcc tttttgggcg tacagtgtgc cagcttcttc gtttttctta
    28561 tcataaatga ctgtcgattg gcttaatcct gattttaacg tttcgacatt tgcttgtttt
    28621 gctaaaataa agaggtagat acttgtcact aagacacaga tcaaaccaat cagcaaaatc
    28681 aatttgttca catgatattt tttccagatg cgctttcgcc atcgatggaa ttgtccgaga
    28741 tatggtctga tccaacgcca aaaactgatc aaagcagctt ttatcttttc taaaatgctt
    28801 tgaaaatcca tttgcttctt ctcctgtcta tttgattcaa tcgtcttatt ttaccatagt
    28861 gaaagagtgt tttcttcctg cttaagttgt agttcaatat gtttttttac gttagtgcaa
    28921 gtagagtaac ataagaatga acagaaaaat gtaagttttt tcttaaatat gttttaaaaa
    28981 tggtacaatt agtctgcgat tgcactgaaa ggagtacact tgtgaaaatc acgatcactt
    29041 tacctatgaa ccatcctgaa acaacaattc gcgacttgct tgaaaaggaa tggttagttc
    29101 ctagaaaggt tcgacacttt ttgcgtatac gtaaaaacgt ttggatcaat caacaacctg
    29161 ctttgttcca tcatgaagta aagggcaatg accagatcac attgttattc gaagaaacag
    29221 attataatta tcaagaagtt caattaggag atgcgaagca catccgtgtt ttatatgaag
    29281 atgagcattt gattatagtg gataagcctg caggaatgaa gactcatcca aatgaaccga
    29341 cagaaaacag taccttactc aatcatttag ctgcttatct cgacactaaa cagcaacgac
    29401 cttacgttgt ccaccgcttg gacaaagaaa caagcggtgc cgttttattt gcaaaaaatc
    29461 catttgtctt gccgatactt ggaagaatgt tggaacaaaa aatgatctat cggagatatc
    29521 aagccatcgt atggggagaa attgccaaag atatgaccat caccaataaa attggacgag
    29581 atcgccatga tcggagaaaa agggtcgtag atgataaaaa tggtcagagc gccttgacac
    29641 atgtcactgt caacaaagta ctttctgaac aaacacaagt ctattgtgtt ttggaaaccg
    29701 gacgtacaca ccagatcaga gttcatttag ctcataaggg acatccgatc gttggagacc
    29761 ctctctacca aaatagaaca gctgaacgac tgatgctcca tgcattagaa ctgcacatga
    29821 tccatccatt tactcaagaa aaaatagtcg gtaaagcttt acctggatta tgggaataga
    29881 aataaaaaag aacagagtct tatcagcaga taatgataag actctgttct ttttgtgtaa
    29941 tttgtctgct tacttttgat gttcgtgttc tgctaacagc aaactaccga taatcccact
    30001 ttcattcggc agtccccaac gaacgatata ttcacttact tgaggtgttt ccatataacc
    30061 acccatcaat tcaacaaatt gctgacggat tttttgaagg agatgatcct gattcattac
    30121 cccaccgcct aaaataatct tttcaggtgc taacgtcaac gtatagttga tcagtgcttg
    30181 agcaatataa taagcctgaa tagcccaaac aggatgatct tgcggcagat cttgcccttt
    30241 gatccctgtg cgtgcctcaa tagacggtcc tgctgctaat ccttctaaac aatctttatg
    30301 ataaggacaa gtaccttcat aatggtcatc tggatggcgt ttcacccaaa tatgtcccat
    30361 ttcaggatgt gcgatccctg aaaaaatttc ttcattgatc acgacacctg caccgattcc
    30421 tgttcccacg gtaaggtaaa tacaactatt ttttccttgt gctgctcctt gcttcaattc
    30481 cccatatgca gcagcattga catccgttgt ccaagcagca ggaatattgt agcgttcctt
    30541 gattgtgcca agaaaatcga attgtgccca cccttttttg ggagttgcca aaacgtatcc
    30601 gtaattatct tttgttttgt cgataccaat cgggccgaat gagccaatcc cgattccctt
    30661 caattcataa cgatcaaaaa attcaaatac ctgatccaat gtttcttctg gtgttgtggt
    30721 agggatactt aatttttcta aaatttctcc accatctgaa accgcacaca caaattttgt
    30781 tccgcctgct tctattccgc catacattcg ttttcctcct cgaatccgat tgtccgaatc
    30841 tcataaggtt ggattattgg gacaaccgct tgcttcgttg gttcttcaag cagattcaat
    30901 atgacagttt ttccattgtc tttagttatt tccaattttt ctaaatgact agacatattg
    30961 aaacctctta ctactacttt atcactaaac ttgctgcgtt tcaaagctgt aattgcaaac
    31021 gtttcacttt ttatcgttaa atattgttgt tttgaaatca atgttccttc atgatgtttg
    31081 atttgttgag tggaaaaagg aatctgtgct gcgtatgcat gcaaataagt agagaatttt
    31141 tcttctggtc catgtagttc aatgctgtaa ttgaaccgat gctcacctag acactgtgct
    31201 tctggtgttg gaaaatatcc ccaatcgcct agttctccca cactgcgaag tagcgtcact
    31261 gcgatttgtc cgtcttctgt tacttcatat tcattcaaac caaagtttcc gactgttaca
    31321 ccgtactctt catcatgaat attgacaaat gcttgctgat gttgcggatt cgtggggttt
    31381 tcccaacttt tagacacatg gtttgggcgc ttcaccactt caaaaatact atctgcttcg
    31441 tgatgttcca catgtaactt tgtaggaaac aagacacgta agcgatgatc tttcatctga
    31501 ttgtcgagag tcgtttcaaa gtcgattttt ttactatctt ttctgattgt catgattgtt
    31561 tttatttgaa ggattcgttt ttctttggat cgttctgctt ttcgataacg aaattccaca
    31621 accatctgct gttctttttc taaacgctcg tctgcagaaa cagggatttc catttcctgt
    31681 agaatactta tttttgctat ttccggtgta tctactaata cttttacttc agagttttct
    31741 ttgttactgg ataggattgg ctgatcacag aaaggttgtt taaagatata ctcatttcct
    31801 atatcgccga tatcttcaaa aatatgcaga ttattcaact ttcgtttgtt tttgcgatct
    31861 tccattgtaa tggtaccatt tttttcaatc gtcaaatgta gagggccgtt ttcgatgatt
    31921 cgtccactct gatgaatcat tgtttccttt tcttctgctt tcgcttcccc ttctacaagc
    31981 gcgaatgttt cccaagaaaa tgctggcatg ttttctaatg gtaaagtcac tttgatcatt
    32041 cttgccatat atggcacacg gaaacggtct ttcggcaaat cataaccaaa ttggacagtt
    32101 tcttcagata aaatagctgg tatagtggcc ccactttttg tttctacatg atacttacgt
    32161 ttaggcaaat tttctaactc ttgatatagt tgttcaggta ttccttcagc gaatcttttt
    32221 ctttctaatt cgatggttat ttctgcttca ccagttttat ccattcctgc agtatttaca
    32281 atgacaaatg gaaagctgtc ttttgggaat ccggtcgtat cgattgctgc ggtcagctgt
    32341 tctaaggaat cttgtgcaag atactttcca acttcatctg ctttttcaaa acgaggtatc
    32401 atttcccgat ggacagaatc gactgaacaa ccgcaaatac tgtcgtgagg atgattttgc
    32461 attaatgtct tccaagcata atctaattga tcatggggat agtttccact aacttcataa
    32521 gccatcgtcg caagtggttc tgtaatattt tctagctgtc gctggacctt ggtattccat
    32581 tgttttaagt aaacccgagc agatgctgta ttggctaaag tataccagcc atccgtttct
    32641 tgacttgtca attctccttc tactgagcct aagtcttctg gcacatcttt ttgaactgct
    32701 tccagatagt cagtaaaatt agaatgaata aactcgtaat ctggaaacag ttcatttgcg
    32761 agatggattg cttttgatat atctttttgt accggttgat gatcaacacc attcatcatc
    32821 aataagtggt tcgtagaggc atattgttct gcatccgcta atttttgctt ccaaaaggca
    32881 agagctgctt ctttttctac tggaatctca ttcccgttgc tataccaatt ggcaaatagc
    32941 agaccaaaga ttgctgtttg atcaggtcct ttccaccaca tctctgagta ttgggaagaa
    33001 tagttttctg cttccaaaac ttgattatca aagccaattg gttttacacc acggccaaac
    33061 gctgctgctg aaataccagc ttgtttcatt aattgaggcg tctgtcccat atttccaaat
    33121 gtatcgggaa aatagcctaa catgacaggg gttccccatt tacggctttc ttccatgcca
    33181 atcagcatat ttctcacgtt cgattccgag ctgataagaa aatcatcttg caagatataa
    33241 aatggtccaa ttctcaattt tccttcattg attgcttgtt ggattgcctg tcttttttct
    33301 ggccttactt gaagatagtc atctaaaata atcgtttgcc catccaaatg aaaactgttg
    33361 aaggacggat caacttcaaa tagctctagt agatcgtcta tcaattcaat cagtcgcatg
    33421 tgatgctgtt cgtaagccat gtaccattca cgatcccagt ggctatgaga aatgatatat
    33481 actttctttt tcatttacga tacctcctac ttttctactc taatatcaaa gtaatccatg
    33541 actaattcgc aaaacatcat atttgcccaa gaaaaccatt ctctcgtata attttcagga
    33601 ttgttcacat cgaatccttc gtgcataagg tgtgttcctg cgtcagttgc tacaagtaaa
    33661 ttcaatatcc gctctttttc agatttgtct gacgttgtca ttccttccat agctaatgca
    33721 atcggccaaa cgtatttttc tggcgtatgg gaggatccaa ttccttttgc gtactttcct
    33781 tcatagaaat atggattttc tttactcaac aatgttcttc ttgtttgcag ataatcttcc
    33841 tcttgttcag aacaatatcc caagtaaggt gcggcgatca gattgggcac attactgtca
    33901 tccatgactg tggcgtttcc cattccatct acttcatatg cataaatcgt ttgccctttt
    33961 tgattaaccg ttcgtccgtg attctgaatc ccctcttgga tctctttctt caatttctgt
    34021 gtttgctgta caatttcttt atcatcgagt atcgtttgaa aaatttcttc cacataacct
    34081 aacacgacca ccgcaaacat attggatggt accagatatc cataacggca agtatcatcg
    34141 ctaggacgga aaccagacca tgtcattcct gtaaaagctg tttttgcacc tcgcccgtca
    34201 ttgatcagcg tatcttcttt tcttgtcgtg tctcgtacaa atgtataagg agagtgttca
    34261 tgatcttgct ctgttttgaa cacgtccaag atttttttga taccttcaat aaaagattga
    34321 ttgaattgat cagtttttcc tgtatttttg taaagaagat aggccaactg tattgggtag
    34381 cataaagaat caatttcata ttttctttcc cagatccaat cgttcatttt tgtatgatct
    34441 gtttggtggc cagcaccgtt agcttcttcg ttgaaggcat tcgcatatgg atcgatattg
    34501 atataaaaaa attgcttttt gactaacccg ctgatcatgt cagctaattc ctcatcttct
    34561 tttgcaatca ctaaataagg acgaacttgt gcagtagagt ctcttaacca catcgctgga
    34621 atgtctcccg tcaataaaaa ggtggttccg tcattttgct ttttgactgt tgtcaacaga
    34681 gtattggcaa atgctgctgt aaaattcttt gcccagtccg catggatatc cccacatttt
    34741 tgtgtgatat cttccataaa tttctgcacc gattttggta tatctttata agccactaat
    34801 aaaaccttct ttctatttga tatatcttta aagattatac ttcatacagc caattatgtc
    34861 tacgctttca aaaaatatct ttttatttac tttttcatcc attatggtat tatttgaata
    34921 tgatatatca ttaagaggtg tttatatgaa tcaaccattg taccagacaa tatttaatga
    34981 tttgcaaacg gctattttaa ctggtgaatt acctgtagac agccaactac caactgaaaa
    35041 agaactttca cgtacctata aagtaagcag aatcacttcc aaacgtgcat tgactgaatt
    35101 agagcaatta ggacttattt atcgcgttcg cgggaaaggc agtttcgtta aatccgcttc
    35161 tccggaacag attcttgctt ctcctacaaa aacacgacgg attctgtttc ttcttccata
    35221 tgtcgctgat ttgtctgttg gtgattttag caagggattg aaccctgtga tgcaagataa
    35281 acagattgat gtcatgatga cgacgcttga ctttctacaa aataaaacag caaaagagct
    35341 aatcaatgaa tttgacggat tgatttatta tgctcttgat acagaacaac atcttgactt
    35401 actttttgag ctttcattga aagaattccc tgtcgtcata ttagataaaa aaatctatga
    35461 gttacctttt cctaccgttc tttccgataa tttccaaggc ggtgcgcttg ctgcctctta
    35521 tttgatcgaa cagggacatt caaaaatcgc ttatttgttt ggtacgcaga ctcatccaca
    35581 atccgttcga cagcgttacc ttggttacct tgaagcattg gacaaagctg gtttgacttt
    35641 ccacacttca ctggatgaca aaagcgcgac attagatgaa ttgctttctt atatcactaa
    35701 gtatgaagta actgcttttg tttgtgaaaa cgatgttgtc gctatccaga ccatgaatct
    35761 cttgagacag catggttatc atatccctga agatttttca attatcggat ttgatgatat
    35821 ccaagcagca gctcttgttg acccgccact gacaaccatc gcacaagatt ttgaacagtt
    35881 aggtaagctt gcgggagatg ctttggtcac ttggttagag acaaaagatc gaccatccga
    35941 tagtaaattt ccagtttcat tcatcaaaag acaatcaaca aaggagaaat aaaatgaata
    36001 tcggtcaaat agatactaga catgcaacag cgaatcagcc aaatttctct aatgggaact
    36061 gccagcctta tactggcgtt ccttttggga tgaattattt tgcaccgcaa actacggatc
    36121 aaaacggcag ctggtggttt catcctgatg accgcgtttt tcaaggctac cgtcttaccc
    36181 atcaaccaag tccttggatg ggtgatttca gtcatatgct gtttacgccg atcaatggaa
    36241 aactacagga gaacaccctt ttccatgctc aaagttctta ccgcccagaa gaaagtatat
    36301 tttgcccgac tcatctgtcg atctgtcaat tacgttatgg catctgttct acattgatac
    36361 ctagcatgta tggcggaatc ttatctattg attacagcaa aaatgacagc ggtttacttt
    36421 tatcctttcc gggacgccat cagctctttg ttatagatcc ttacacagtg gaaggaaaaa
    36481 tcacacattt tgctggttca gaagatcctg atttttcttt ttattttata ttgagatttg
    36541 aatatccttt aacaattgat gagttagctg tttccaacaa aaatagcgac tcgatcccgt
    36601 tgtattttga acagacaaaa aaacaaacta tccgatttgg gacatctttt atcagctcgg
    36661 aacaagcagc ttataacctg gaactagaac aaaaccaaag caaagagact taccttgctc
    36721 acagtcaaga acaatggcag tcctattttg atcgtataca gctcacacac catgatcaac
    36781 aacaattgcg gacgttttat cataatttat atcgggtgtt tttatttcca caaacatttt
    36841 atgaaattga tcctagtggg caaaaaatcc actatgatac gactagtcga tctataaaac
    36901 ctggtgttct ctatacaaat aatgggtttt gggatacgta taaaacggtt tatcctcttt
    36961 attctttgat tgctgtagaa aaatacgaag aaatgctgga aggttttttg aacagctata
    37021 gagaaagtgg ctatttgcca aaatggctgt ctcctgatga acgtggactt atgcctggga
    37081 cattgatcga tgcggtcatt gcagatgctg ctgtaaaaga tatccgacga gacttgatgc
    37141 ctgaatttct aacggcaatg gaaaaaggtg ctacggttca aagcaaacat ccaaattatg
    37201 gacgccaagg aacagaagat tacttgacat atggctatgt tcctaatcac taccacgaat
    37261 cagtcaatca cacattagac tatgcttata gcgatttttg tattagccaa gttgccaagg
    37321 tactagaaga agaggaaatg acgaagaaat atcagcagca atcattgaac tatcaaaata
    37381 tctttgacta tgagtcagga tttatgcgtt caaaagataa agatggcaag ttcagagaac
    37441 cattttcagc taatcgttgg ggacaagatt atgcagaagg aagtgcttgg caaagcagct
    37501 ttgctgttta tcacgatttt tcaggactga tcggaaaata tggtggcagt gagagatata
    37561 aagaaaaact cattgagctg tgcaatcagc ccccaacgtt tgacccagga ggatatggtt
    37621 ttgagatcca cgaaatgagt gagatggccg cgatagaatt tggacaatta gctatttcaa
    37681 accagccaag ttttcactat ccttacttgt tcagttatat aggacaacct gaaatggcac
    37741 agccactgct taaacagttg atgactcaga ccttcgacga ttctccaatg ggttaccctg
    37801 gagatgagga caatggaagt atggccgctt ggtatatctt caatagtctg ggattttatc
    37861 ctgtcacgcc tggaaccggt gaatatgtta tcggtatgcc attaattgac aaggctgttt
    37921 tgcttttgtc aaatggaaag gaattgacga ttgaagcaac gcctaatcgg ccgcagcaac
    37981 aatttatcca taaaatcaaa cggatggaca aagaatatac gaaattatat tttacccatc
    38041 aagatttgct gaaaggcggc acgatctctt accaattagg gatcatccct caccctaaga
    38101 aatatcaagc aaaagatttg cctttttcct tatcaaacta taattaacaa gaggttgtga
    38161 aaaagctgtc ctgcatcaag taataagaac agccaagcaa aaatagatcc tcatattttt
    38221 cgtttggttg gtcttattac cgcagatgca agcttttgaa caccgtttat tgagaggttg
    38281 tgaaatcagc gttctgacct gagtattaga gagacaaatg gcaaaatagt tcctcatatt
    38341 ttgccatttt ttgagctaat accgagggtc agctgattga acaccgttta gtggagaggt
    38401 cgtgaaaaag ctgtttagtt tcgagtatta agaaaaattt tgtgaaaatg gctttccaca
    38461 tttttgcata aatttggctt aataccgaga aactggcttt tgaactccgt ttatcgagag
    38521 gtcatgaaaa agctgccttg cctcaagtaa taagaacagc ccaaaattag atttctagac
    38581 aattttttat aagttatttc attacattgg ctttttcttt tatgattctc cactgttttc
    38641 tcggtactct ttaggggatc tgccgacgat tttcttgaat aatttagaga aatacgtggt
    38701 gttgttgtag ccaatctcac ttgctatctc attgatgttt tgattactgt gcaaaagcag
    38761 ttgtttcgct ttttccatac gtaaatggtt caaataagct gaaaaacttt ttttcgtttc
    38821 ttttttgaac agctgtccta gatacatgac atttaaatgc aggttttctg acacttcttt
    38881 gagtgtaagt ggttcttgat aatgctggtg caggattacg attacttttt ccacattgtc
    38941 actgtacttt ttctgtctct gatgcttttt gatgaatgac agaagtagct gctgaagttc
    39001 ttgcaccgtt tttgcctgat ggattttttc gattccttgt aaatattcct catcttccag
    39061 atcaatcaat tcccgttgaa tctccataaa cagtaaaaaa ctggaatatc gtatatcttc
    39121 cggcatcatg gctgctaact gaaactgttc aaaaaaatca gtgatcattt tttgagcgac
    39181 ttccaattgt ttattttgca gcacgcgtct gaaacttgaa aaatcgatgg tttgatcttt
    39241 tgtttctgct tgtactgcgt aaaaaacatg ctcgtcttta tctccataaa attgatgcaa
    39301 ctgtagattg tctttcgctt gttggaatgt ttcagggatt ttgtccaaag aatctgtctc
    39361 ttccccgata ctgatcagcc attcctgatc aggaaagttt tcttgaacaa aacaacagaa
    39421 gccatcaact tcatctgcct ccaacaacaa cgtgatcaat acacggtctc cgtaatttcg
    39481 ttgatagtaa aagatttgtt gccgttcttg caaccatcta ttgataagag tatcatgagt
    39541 tcttgccagt tgaatcaata ctatcctatg ctgcttctca cttatttgtc ctattatttc
    39601 ttcttcactt atttcatcca attcttcatt caaccattga ctgaataaca gttcttgata
    39661 gatttcttgt tgattttttt gttcattttg ctgatctaac cgtgttttga ttttcttgag
    39721 gctttcaacc aattcgaact tattcacggg tttcatcaaa taattcacgg cgcctaattg
    39781 catacctcct ttcaaataat cgaattcttg gtatcctgat aaaatcataa attcaaaatt
    39841 atgacgttct ttttgagccg cttcaataaa ttccagtcca tttatttctg gcattgtcac
    39901 atccgttact actaaatcaa tctgtcgctg ttcaagtaca gctagtcctt ctttggcatt
    39961 ctctgctgtt gctactattt gaaagcctaa actttgccaa tcaattatct tttttaaccc
    40021 attcaaaatc atgtattcat catctaccaa taacacttga tacacgctca tccctccttg
    40081 aatgtaatag aaacggtcag tccacctgtc tcattattct caagcgacat ataataactg
    40141 ctgccgaagc tggcacgtaa acgttcattc acgttttgca gaccgataga accgtgaagt
    40201 tccactttag gatgagacag tttttcttca atctgtttta gccgtttttc agtcatccct
    40261 tttccattat ctttgatgat gatccttacc cgtttgcctt cctgcaagac tttgacactt
    40321 agcgcattat cgaatcgagt aaaatcaata ccgtgtttaa aataattttc aactaatggc
    40381 tggatcacaa atttaggtac ttcgatcttt tccaaatcag gatcgatcat aaaatgatag
    40441 gctactcgat taggataacg catttgatac aaatagacat atttttcgca aaagtccagt
    40501 tcttctttta aagtgatcgt tttctcttga ttcgtattgt ttcgaagcaa agcggaaaac
    40561 gcatacacaa catctgctaa ttcttcactt ccttcgctga ttgcatacat tcggatatat
    40621 tctaatgtat tatataaaaa gtgtggattg atctgtgctt gaagcgcccg catatgtgcg
    40681 tcttgctgtt tgatttctaa tttgtagatg tcttctacaa actgattgat gctatccaac
    40741 atttcgttga taccgattga aagttccttc agttcatatt ccgtgtttgt tatgtcgatc
    40801 cgcgtctcta aattccctgc tgctgtttga tccatggcct gcatgacgat agatacttgc
    40861 tgtgaatatc gtttgaatgt tttataaaga aagataagca gtatattgtc taaaataatg
    40921 ataccaatga tcagcggggc aagatttttt cccgtttcga tttttacact ttttttatct
    40981 agtacagcta atatacgata atcatcagac agttcttggt gttgaacaaa attgtttttt
    41041 tccagatcgt caatcggcaa ttgtgaattt ttcttcagac tctctgtgat gatcatttct
    41101 tgtctttcaa acgtttcttt agctatttta ttatcatgga atgtgtatag tcgatttgtc
    41161 gttccagaaa tcatgtataa agagagtcca ttgaatgacg ttagattttc taaaatcata
    41221 tctagttctt tcttttgaaa accaataaaa atacttcctg actcagctcc tccttgtgtg
    41281 ataggcaact tgatataaaa ggcgtctagt aattttggtg tccccttttt tatttcccca
    41341 cctttgtttt ctctagaaga ttcataatac tccggtagtt gattcaacac gatatatatc
    41401 gcacttagtt cttcataatt tgcgtagaga tctttgattt gatttgggaa agaaactaat
    41461 tcatcggtac tgttttgctg ttcgtataca tacatcagat actgatctat gggttttgtt
    41521 aagtaggtcg tcacattttc gatcttttcg gaattcccta caagctggtt tttgatgatc
    41581 ctactcaagg ttgttttatc attcagcatt ctgcttgtgc tttgaacggc atcacttgtc
    41641 atgttttctg cctgtttttg attttgttcc caagtatgga tactaaaaat aacggtagca
    41701 gtcatcgtta caccgatcat gataaccgcg tatttccgca acagacgatt tagtaaggtt
    41761 ccttttgaaa atagaatccg aaacttattc ataactttcc aactgtttat ctaattcttc
    41821 acgccaatgt gttgtcatcg taccattcca aaccgtcaaa agaccaatga caccaaacag
    41881 gatcaatcct ttgaattgcc aagtcacgcc taaaattata ccgctaccaa taattatttt
    41941 tagaaaagac gaaaagctgg aaaaaaccga aataaaactt agctttagca gattaggaac
    42001 agagatcgta tattcactat ctaaaatcat actgtattga taagtagcaa ataggcagag
    42061 caaggcaaaa agtaaaataa aatcaatagc taaaaaaatg agccctttga tttgaacaga
    42121 taaatataaa ttgtaactca ataaagcagt accagataaa aataaactaa atagcagatt
    42181 gcctcttaaa aaatttcttt tatatatatt ccagcctctt tttattgtga tttctttata
    42241 ctcgaatccg tacaaataaa atagttcatt gactgttttc catgccgcac ctaatccaaa
    42301 gatgatcccg ccggcaaatg tatatatcca gaaatacaag gttagtttta taatgaccca
    42361 gatccggata aataactctt ccaaaacctt ccctaacata tcttctcctc caaacattaa
    42421 gtttatactt tctcattata caaaaaaagg ttgggcaatc agcaccttga cctgattatt
    42481 agagaaacaa acggaaaaat agttcctcat attttgtcgt tttgtgagcg aataccgagg
    42541 gttagctgat tgaacaccgt ttaccaagag tttgtgaaat agccgcttag tttcgagtag
    42601 taagaaaaat tttgtgaata tggctttcca catttttaca tatatttagc ttaataccga
    42661 gaaactggct tttgaacacc gtttattcgg aacaagaggt tgtgacacgt cttttgtcac
    42721 aacccctttg tctttattca ttattattct tgtcggaact catcatattg tttttgcatt
    42781 tctttcaata ccttatcata gccagccttg tccaaagcgt ctttcaattt cggtaatgtt
    42841 tcatctggat caacagtccc tgtattcaat ccatctaaat attgattcat gacattagaa
    42901 atattactta attctgtttt gacactgtca gtgttgaagc tgaatcctaa aatcggtgaa
    42961 gtttctgcat cagcaatcga ttgatcacgt ttggcaatca tgtcatccgt aatagactct
    43021 tgtgtatata gaatcttgtt gtttcctgta ttccaagcag acatatgtgt atttggctga
    43081 taaccatcta gcaatttgat tttatcatct gaaccatcga ctttttccca tgcttctccc
    43141 tcgatccccc aaacaagccc attcaataat tctggatcac tgttaagcag ccctagaagt
    43201 tctactgatt tttctttatt ttttgaagta tttgatacga caaaatttgc catttgtgct
    43261 tgagctgtag attttagtgg aacagtaatt gcttttgaga caagttcttg ttttgctgca
    43321 tttgtcaaaa ttgtatcgcc ataatcatac ggtccttgtg tttctccacg cattagccaa
    43381 gtatttcctt ctagtggata atccttattg ctcgttgcag cgtcacttgg aatgagtcct
    43441 tgtttgtacc agctatgcat tgtacgtaac agtccgatat acgtttcatt atcgtattgg
    43501 ttgatgattt tcgaatcatc tccatccaga tcaatagcaa atggtaacgt attccctaaa
    43561 ggataatcaa agttcccttg gactttgaag ccttgtccaa tggcaaaagc tgccgtgttt
    43621 ggttcttttt catggaattc cttcaagact ttttctgcat cagcgtaaga ttggattcca
    43681 tcaattgaaa gatcgtattt atctagtaaa gctttgttaa aagtaagtac ttgttgagca
    43741 aagacatttc cattgactgg gaaagcatat aattttccat tgaccagatt tcctttaata
    43801 tatgcttcat ctaaatcatt ataagctttt tcagcgtact taggcgctaa ttcagtcaaa
    43861 tcagcaaagg ctcctttttg ggcattggaa acatagttgt tcgcaaaggc gatatcataa
    43921 ttttccccgg aagaaatgat gacgttcatt ttcttttcgt aatcgcccca gccaatgtaa
    43981 ttgatattga cttttacacc gatctctttt tcgattcgtt tgtttgctac ttccatcaat
    44041 tgatcgaaat tatctggttt atctccgatt tgatacatct gcaaagtgtc cgaattgcta
    44101 gcttctgcct ggtctttaga accagaacct ccgcatgctg ctaatgttcc caacaacaac
    44161 gctgaaacac ctgtaaaggc tagtttcttc cataacttca tttttcttcc tcctaatttt
    44221 atgatttata tttttgtttc tttattcttt tactccgccg attgttagac ctttgacaaa
    44281 atgcttctgg aaaaatggat agctgatcgc aataggcaac gtcgagatga ctacgatcgc
    44341 cattctggca gattctcctg gaactgaggc taatccgcct gtcaattggc ttcctgctcc
    44401 tgaattttgt gtcagatatt gaatattact ttggattttc atcaaaagat actgtagtgg
    44461 aactagctta tcatcttgga tgtatagtaa agcattgaac cagtcattcc agtaacccaa
    44521 tgcggcaaat aaactgattg tcgcaatacc tggaacagct aacggtaaaa cgatctgaac
    44581 aaatattcgc agttcgctag ctccatcgat ccgtgccgat tcaataatcg aatcagagac
    44641 cgaacgttta aagaatgtgc gcatcacaat aatattgaag ggactgacag ccattggcaa
    44701 gatcaatgcc caaatcgtat cttttaactg aagaagattt gtcataacaa gataattggc
    44761 caccatccct ggtgagaaca acatcgtaat caaacaaaaa acggtaaaaa aacgacggaa
    44821 tggaaagttt gaccgtgaaa tcgcataagc atataaagaa gtagccgtgc tattgatcag
    44881 tgtacctaaa acagtaacaa gtacagtgac gaaaagcgct tggaaaattt tatcctgcat
    44941 ctggtcgaac aagtacgtat aaccaaatat actgaacttt tctggccaaa aactgtaccc
    45001 gtgagtcgac aatatggact catcggtaaa agagatggcg ataacaaata taaatggcaa
    45061 aatacaggaa atagcaaaga gtgcaatcat tatattagag aaaaaattag ccgtcttatt
    45121 gaaagagcgg acttggactc tctccacttt cttttttttc atttttttcc tccttagaat
    45181 aatgcagaat cgctatcaaa acgtcgggcg atcgtatttg tgatcatcaa caagacaaag
    45241 ccgacaactg attggtaaag tcctgcagca gccgtcatac caaaatctcc tgtggatgtc
    45301 aggccattgt agatatacgt atccaaaact tgagtcacat catataatgc accggaattc
    45361 ctaggaatgt tataaaacag gccaaaatca gctcggaaaa tgtttcctac ggctaaaatc
    45421 gttaaaatcg tcattagtgg aataagttgt ggtatcgtca catgtttgat ctgctgccat
    45481 ttgctagctc catcaaccat agcagcttca taataagtcg gatcgattcc cataacagat
    45541 gcaaagtaaa taatgctgtt ataaccaatc cctttccatg taccaatgaa caccaagata
    45601 aacggccaat atttcggttc attataccaa ttgacagctt ctcctccatg tccagtgatc
    45661 cactgattga atattccttt gtcaggactt aaaaaagcgt aaacaaagta actgataatg
    45721 acccaagata gaaaataagg tagtaaggac atcgtttgat aaactttaac gagtcgttta
    45781 tttctcaact cgctcataat gattgcaaat acgactgaga tcagcagatt caaaaggata
    45841 aatgctacat tatataaaat tgtattttta gtgatgagaa atgcttgatc cgaagaaaat
    45901 aaaaatttga aattttccca acccacccaa ggactttccc tcaagctagc caagaaccca
    45961 tctgctgaaa tatgaaaatt tttgaatgct acgacattcg ccattacagg tatgtaaaag
    46021 aaaaaaatca tccaaagcat acccggtaca gccatcagga caagtgcttt ataacgccat
    46081 agattcataa aaaaatgatt gaaccccttt cgttttttca tctaaaaacc cctttcgatt
    46141 cattcgcaac gtaattatag cgctttcaat aatgagaata aataaacaaa gtatagggaa
    46201 aatgaaacaa agtataggag aggttgtgaa atcagcgttt tggcctgagt attagagaaa
    46261 aaaacgggaa aatagttcct catattttgc cgttttttga gctaataccg agggtcagct
    46321 gattgaacac cgtttatcag aggttgtgaa ttcagcgttt tggcctgagt attagggaga
    46381 tcgtgtcctt actatctaac tctgagtcac aaggaacaat ggggactgta acaaaagtct
    46441 tgtcacagtc ccttattccg aacaaacggt gttccagaag tagcttctac ggaaataagc
    46501 cgaaatttca caaaaaagcc atccgaaagt cagacggaca agtctgcttt tcagatggcg
    46561 ctacaactac tctgcttatt cttttagcta tccattcaat tatttttctc tcacttgttc
    46621 tagctcttct ttggtcatgg gtcgatattg ccctttattc aaatctttag gcagccaaaa
    46681 ttttcccata cggattcttt ttaaatataa gacttctttt cctactgctt tgaccattcg
    46741 cttaacttgg tgaaactttc cttcatgcaa aatcagacgg ataattgaag tttctgtctc
    46801 ttgatctact tgatcaattt ggagttttgc cggcaatgtc tgctcatcgc catcaataat
    46861 cagtccttct gcaaataaac ggatatcttc ttctgtcatt ataccgctaa cctcagctag
    46921 atattctttc tccacatgtt ttttaggtga tagtaactga tgggcaaaca ccccgtcatt
    46981 cgttaaaatc aagaggccct ctgtgtcttt atctaatcgg ccgactggaa aaagatcttc
    47041 ccgataatcc tggtcttcca ataaatcgat tacggtttga tcatgattat cctgagtagc
    47101 agaaatgact cctgcaggtt tatgcaaaat gtagtaaaaa tctttttgat acgtaatgat
    47161 ttctcctaaa taagtaaccg catcttcgaa ttcatttact tgcgctttat cgcttttcac
    47221 cacttgtcca ttgacttcga tcgttccttt tttgattaat cctttgactt ctttgcggct
    47281 gccaagtccc atatctgcta aaaacttatc taaacgcatg cgtttccccc atttcaaaag
    47341 agcatcaatc tagctcttct gattcactta ttttattttt aatttatgtc gtaaacgcgc
    47401 tattcctggt cctagtagtc tttctgccaa gcggattttc aaagctaaat aaccatacac
    47461 taaagcccct atacctgcta ctacaagaat caacaataga gactggaatt tgctatcttc
    47521 gtttaaaaaa gcaccaaaaa tcatctttgt gatccacgaa gccaaaagca taatcaaggt
    47581 aagaataaag atcagcaatg tcctgcgcca gacaaaactt ggtttaaagc gggctacttc
    47641 atggattctc tttaagatca aggtacaaga cacagcaaat ccgatcattg tcgccaataa
    47701 agggccgtat acttcaaata aacgaatggc tgggtattga agaaggagtt tcactagaaa
    47761 cccaataacc aaataattaa ttgccgcctt gttttcaaac attccttgca gcatgttgga
    47821 aactagcata tatagtccta ggaagagtcc tacaaaactt gcttggatca gtacattact
    47881 tcctagagaa tccggtgtat aaaataatgt atttagcgga taggcaagta acataacacc
    47941 aaatgtcgcc ggaaacataa aaaatgaaaa caactgtaaa tttccgcttg tcaattttgc
    48001 cagacctact cgatctttca acgtaacagc ttctgtaatc aacggtaacc cagtagacgc
    48061 gatcgatgtt gccaatgcaa taactaccat cgtcaactta tctggattgg cactaaaaat
    48121 cgaaaaaaga tccagtaact gtgcattgga atactcggtg gatgcagaca tgatcttcat
    48181 aaaagtgaac tgatcgacta atttgaagat cgttacccct gaacccacaa taataaacgg
    48241 aatcgcttct ttaacggtat ctaacaacaa ttccttcgtt gcaatattta ttttgttttc
    48301 gctgtagtga ataaacgccg atgtatacgc ttgatgtttc ttcaaaaaat acaaaaggac
    48361 aagaatactt gctagcatac cgataaatgc cgcgaaagtt gattgcgtga ccgccgtcac
    48421 atagtcacca tccatgactt tcatgatgat gaatgtagcc aatagcatat aaaaaatacg
    48481 tgccacctgt tctacaatct gcgacagcgc ataaggcatc atttcttgat tgccttgcaa
    48541 ataccctcgt atcacactca tacaaggaaa aaccaataca gcgatactca aagaacgcat
    48601 cgttggaatc agttcttctc cgccaccaga agcatgagct agccaaggag aggcgatgta
    48661 catgaacaaa gcaaacaaca ggcctaaccc gcccatcatc tgtaatgcac ggataaataa
    48721 tcgtcgtgaa gtgccatatt cattcaatga attatagcgt gcagtttgtt ttgcaatcgc
    48781 agcaggtatt cctgctgtag agatcagtag aaacaatgca tatatattgt atcccatatt
    48841 gaataatcca ttggcagcct tagcattttc gcccatccaa gcataccagg gaatgatata
    48901 gacagcgcct agcaatcttg aaatgatatt actggcggtc atccaagcag agcctcgtgc
    48961 cattttttct tgcggtgtta attgatctaa tgctggtttt ctttgattat ccatcggtca
    49021 gattccaact ttctacaaaa cattactatc attttaattg gtaaaacaga aactggcaat
    49081 cgattttata taacttttat aagaacaatt gtttttttga attcggtttc gtttttttgg
    49141 taaagtaaag aaatatacag ccttttatgg ctaacattta taggagatat caatgacaca
    49201 agaaataaaa aaactacccg ttatattttt aggtcttttc tttatcacag ttggattgaa
    49261 ttggttcttg ctccctcacg atatagcttc cgccggagtg ggcgccatcg gacatttagt
    49321 tgaaacggcc ttttctatcc aacgctcagt tactgtttgg agcatcaatc ttatgatgct
    49381 gcttctagcc gctgtcctat taggaaaatc agtatttttt aagactgtag cgggaagtct
    49441 gctttttcct gttgttttag agattgttcc aaaagtggaa atgatctcct cacatttctt
    49501 ttcactgatt tcaggaagtc ttttgttcag tcttggggtt tacacattgt acacagtcgg
    49561 ggcctcaaat ggcggtataa cgataccgcc gattattttc cacaaatttt ttcggcttcc
    49621 aatgccgcaa ggacttttac ttaccaatag tcttatcgtc tttttgaatt attatgtttt
    49681 tggattgttg gagacactat tcgttctcct atctattaca gtcagttcat tgtttatgaa
    49741 aatactcatc cgcttgtccc ctgtgtcaag aaaatttgaa taaagctgga ttttgtcata
    49801 gcggaaacaa acgatatatt aaaaagagtg tgctataata aaccaagaaa ttgaataaag
    49861 cgagggatca atcaatgagc ttctctttag aagacatccg tcatttacta ttaaaagaaa
    49921 atctattaaa agaatttgtt tcaacaagag gctggcatct tgatgtacca gaaaaagctg
    49981 aatttcttca gttaagttat gattcaagaa aagctgatgc ttctactttg tttttctgta
    50041 aaggaatgaa tttcaaagaa gaatatttgg attcagcaat cgaacagggt attcaatatt
    50101 atgtatcaga acaaccatac gaaaattcag cagtaggaat catcgtaacg gatatccgta
    50161 aagcaatggc gcttcttgct atggcttttt acgactatcc gcaaaataaa ttgaaagtga
    50221 tcggattcac tggaacaaaa ggtaaaacaa ctgctgcgta ctttacaaaa gcaatcttgg
    50281 atcacacaac aaataaaaaa acagcattgc tttctactat gaatacaacg ttagatggca
    50341 aaacatattt caaatcccat ttgacaacgc ctgagtcatt agatttatat cgtatgatgt
    50401 cagaagcagt tgaaaatggt atgactcatc tagtgatgga agtttcttca caagcttaca
    50461 aaacacaacg cgtatacggc ttgactttag atgtcggaat cttcttgaat atctcgcctg
    50521 accatatcag tccgatcgaa catccgacat ttgatgacta tttctattgc aagcgacaat
    50581 tgatcttgaa ttcaaaaaca gttgttttaa atcatgaaag tgactatttt gatttactta
    50641 gggaaacagc cgatctattc cagattccaa cgatcactta tggtcgttcg gaagaaagca
    50701 attatcaagt gatccgttca gataaaggta ctcacggttt tactttatct tctcatgaag
    50761 atcgcttagc tatctgcgat actgcttatg atattttgct ggctggagga ttcaaccaag
    50821 aaaatgcagc cagtgcgatc attgccgcag cactaacagg tgcctccagt caagatgcac
    50881 aagacggatt aaaagaagct cgtgtaccag gccgaatgga tcaattgatc caatccaatg
    50941 gagcgcatgt ctatgtggac tatgcacata attatctaag cttgaaaaca ttgctgaaat
    51001 ttgccaaaaa tgaacatcca gatggccgtg taattgttgt attaggcagc ccaggaaaca
    51061 aagcaatctc ccgtcgacat gattttggaa aagtgctatc agaaacagct gacatcgcct
    51121 ttttgacggc agatgaccca gcatttgaag atccgaaaaa aatcgcggaa gaaatcaatg
    51181 aagcaattac taatccagat ttgatcgttc attatgaaat ggatcgtcct gaagcgattc
    51241 gacgcgcttt agcagaaagc gctccgcaag attcagtcgt tattgcggga aaaggcgtgg
    51301 atccctatca aaaaatcaat ggtgtagatg aaccttatga aggggattat gcaatcgtga
    51361 agcggttgat tgaagaataa tggtatttat atactagtgg tttcccattt ctaagaaaaa
    51421 aagggactgt gattttttgt cacagttcct tttttcttag aaatcatttt aacttttcac
    51481 tagctaattc tgctgccttt tctctttctt catttaataa tttattatca tagaatttga
    51541 taaatgggaa ccagataatg aatgcgatga ttgcacaaat gactgctaac acagcagctt
    51601 tccaatcacc accactacca acaaatgctc cgatcccgac tggtgaaggc cacggcatct
    51661 gtgcaagcat cggtttgacg atttccagcc gaatggcaaa ataagcgagt gtagcagaag
    51721 ccatcggagc taagaaaaac ggaaccgcta aatagggatt gtagacgatt ggcatcccga
    51781 aaatgattgg ttcattgata ttgaataatc ctggtacaag tgaggctttt cctaacactt
    51841 tcagctgatc agatttcgcg aggaatgcaa taaagatgat caatcctaaa gtcgcacctg
    51901 atccaccaac ggttacataa gaattgttga attctcctgc caacggataa tttgcgcctt
    51961 gtgcgttagc tgccatatta gctaatacga tcggggtcaa gaaagaagtg atgatattcg
    52021 ctccatggat ccctacgatc cacaatgcat ggatcaagaa ataaatcacc atgacaccaa
    52081 gccatgtatt cgtcaactgc gtaacaaacc caaatgggat agcaatcatt ttgaagatat
    52141 ccgttcctag tgcaactaat aatccattga tgatcatcac cacaaacgca atgacaaatg
    52201 ttgggatcag agcagtgaaa gaacgagaaa ctcctggcgg aacaacatct ggcattttta
    52261 tgacccaatt tctcttgaca cacatacaat acaattcgac cgcaataatc gacataataa
    52321 tagctgtaaa gattcctgaa gttcctaaac gttcgacaaa agagcccatc ctaataccat
    52381 ttactacagt ttctgtctca ttgatagaag caatcaagct gattttacca tcagtcatga
    52441 tcaattcagg gatacacata aagaatgcaa aaacagatag taatgccccc gtgagcggat
    52501 taacatttaa tttttgttca tctcgttcaa ttgacgttaa ttcataagca aacacaatgg
    52561 caaagtaaat agataaaatc cccatcgtca ttgtattgac gatcatgtac aagtcactaa
    52621 ctttgaaaaa agttgcatta aaaaatcctt ctaaaaatgg gaacggtaat ggcaaaatat
    52681 ttaaaaccaa aaacatcgag cctacaatcg tgaaaggaat agaagccatc cccgctgcca
    52741 tgacagcccg aacgatttta agttgcgcaa ttttccccat aggtcccatc aggtatttct
    52801 gcaaaaaatc aaacattagt tattctcctt tcctaaatat aacgcttttt catattgttt
    52861 aatacggata tactgttggt cttggttgag tgaaattttc tttaaacgat actgtataaa
    52921 tgcactggca aaaataccgc ttacaacaag aatgaaaaca aataactgtc ctccattgtt
    52981 atttgccata aaaggataca agaatgtaaa tcctgaggta aacaacactg gaatcactaa
    53041 taaattaaag acactctgga acaaaaaata ccactttgtc catggaacgt tcgtttggtg
    53101 ttttcgataa agctttactt gttctcctac tgcaggcaaa atagctaaaa tcagaatcat
    53161 cggtaaacta cttcctaaac ttttagctga tagaagcaga atcatccatt gcatgttcat
    53221 gaaaaagaaa aaggcagtca ggtaacgtac gattagataa cgattgaaat acatgttttt
    53281 caaactaagt tgcttttttt ctaattcgat tttccttttt actgtatcct gcacaatgat
    53341 ccttcctttc tatttatttt tttgatacaa ataattcatt tcctgtgcaa cttccaataa
    53401 tgtcatcgtc gtcatcagat gatcttgtgc atggaccatg ataatttcca tttctatttt
    53461 tgtcccgctg gcatattctt tcagaagttg agtttgtgac tgatgcgcat gaagaatctc
    53521 ttcatttgct tgtcgcaact tctcttctac ttcttcaaac atctctttac gcatcgagcg
    53581 aaatgcttca tgtatcagtg tccgtgcatt tccgctatgg aaaatgatat caaaagaagt
    53641 cacttgtagt gtttcactgt ttattttttc agccatctgt tttcctcctt attcgatcag
    53701 tttgataaat ttactgctga aattctcaaa aataggttca gctaagattt cctgctgtac
    53761 ttttagctgg tcaactaacc taacgattgc tttagtcacg accgtaattc cttcattttc
    53821 gacataagaa ggcgaaacta aaaaaacaaa atgaatttct tgatattgat cccactgcat
    53881 cccagaagga atcaatgcaa cggctacctt tgtttcgatt ccaactggaa cagcgggatg
    53941 tgggactgcc actgtatcac tgaatatgat ttgtcccata ttttcacgtt gctggatctg
    54001 ctttcgcatt tctcttatat atccttcttc ttcatttatg ctcagctttt gcagcaaatc
    54061 atgaagaatt tcttcctttt tcggttcgta cgtataagtc ttgaaaaatt tttcagacaa
    54121 ctgttcggtg taaatctgct ttttttgctg tagagaaaat gctggtatcg gtctatctga
    54181 ggaatgatag ggtatagatt ctccaactac ctttcgtatt ttacgaacat catcttcatt
    54241 caaaaaaata ctgacatgta aaactggaat tttgaaaaac attgtcgaaa gatcaataga
    54301 agaaataatc aggtcgattc cttttaaagt tgtttcattg atctcataat agccttttac
    54361 acttaccact gtaatatttt taccgaattc actgactacg cgattcttta atagttgggc
    54421 actgccgtaa cccgttgcac agataatcaa tgcatgtagt ttatgcgcag ctctttcttt
    54481 ttccaatgcc gccatgagat gcaaagccaa ataggcccat tcatcttcat tgatggtata
    54541 gtttttcaaa gccggcatgt tgctgaaatg cctttttact gcgtcaaaga ctttgggatt
    54601 ttctttcttt atctcctcag tcaatgggtt ctcaatgcga atacctcggc tcaatcgaat
    54661 catcatcggt gacaaatgat cgagtagtcc attgaaaagc tggagatcct ctactaatga
    54721 aaaatgaaat tcctgagaca atcttttcag aactttcgct aattcctttg atagttcctg
    54781 atcattttga ttttctttgt gattcgactt agccatgaga tgtaatgtca aataagcaat
    54841 ttcttcttcg ggaaacgata cacctgcgat tacctcaata cgttgaacga tccgctgcgc
    54901 cacttgatac tctactcgct tagaaacttc ttgttcgatg cctaattcct tgatttcaaa
    54961 cccttctcgg agccgtttga tccccaaagc caagtgtaaa gtcagattct gtatgataaa
    55021 atccgaaact tttaacttag cttctcttgt ttcatcgaga atgataatga ctagctcttc
    55081 aaaactgatg tctgggaaaa aacggctttg ccctaaatat tctttcaatg aatttccata
    55141 atggtttcca aaaaaagtat ccatgataaa atgccgtcga tttctttctt ccccttcgat
    55201 ccatgtccct tgaccatgct tagaaacgat ttttagtgaa tatggaatca atcgctcctt
    55261 gatttcttgc atgtcctttg tcaaactgga acgactgata taaagctctt ctgccaaatc
    55321 atccataaaa agaatggcat cttccaaaag caattggttc aatatatact tttgtcgatc
    55381 ttcggactca taaaatcctt gcggttctct agcatatcca ggtactattt cttgccgact
    55441 caaaaacaag tcaaatgtca gtctttgtaa aatatgcagt tggtagccat aacctggttt
    55501 agcaatgatc ttacctccgt ttttttctac taactctttg atccgctgca agtaattacg
    55561 gattgtccga tcagataata acaattcaga agctaaacgt tgactggtga catactcctt
    55621 cttgtgatca atcaaatatc tcaacagcaa tttttccttc tgtttcatta tcatccactc
    55681 ctattccatc atatgttctc ttcgatcacc tctgctaact tctggatgcc tgtagggatt
    55741 gggacatacg cttggaaagg gatactaaca acaggctttc caacagattc tcctaatttt
    55801 ttgaatttat ccaaaaacat cgtcgtttgc gggctgatca gaaataaatc aaaatcacta
    55861 ttcttaatca tattatcgcc ttctgtagct gaaactgcat ctacgagtac ctcttctctt
    55921 ttttgcttaa agaaatccgt tgtctttgag gccatcatcg aggatgacat tcctgccgca
    55981 caaataatca atgctttttt cataaatcaa tcactccttt tatttttata aaccaagcat
    56041 atcttgtaag cgttttctat tcaaaatata tatttccgta gcattgcgga aaaaatgtgt
    56101 atcatatctt gaataataat ttctggcacc gtgatatact agtgatagaa ttttttcagg
    56161 aggggattta gtgagtatca cagtgaatat tttgtataca agtacaaatg gacaagccag
    56221 aaaatttgca gaagaaatgg tcgaaagaaa cattgtcaaa gcgattcgtg cagaagaagg
    56281 aaacgagaaa tatgactatt actttccact agaagatcca gaatctcttt tactgatcga
    56341 ccgttggaaa gatgaagaag caatcgaaaa gcatcacaaa tccgaaatga tggctcaaat
    56401 aaacgaactc cgtaaaaagt ataaattaaa aatgaaagtc gaacgtttca ctgatttacc
    56461 gtaaaaagat acacatggaa tgatagcaat ttatcatcca tgtgtatctt cactttttcc
    56521 ttatttttta ttcgatctca tctaatgatt caaaccgtgt ttttctctta tttttcggat
    56581 aagtatttca gtcaccccaa tatacatgat tcctaaacat accccaagga tattctcaaa
    56641 aatgcggatc gttactgctc ctggaacccc gaataaactg gcagtgattg ccaaagcacc
    56701 aaaagaatta aaaactgttt tatatctata ggtagaacaa acacctaaag ctagaccacc
    56761 taatataccg acccagttaa aaggaataaa ttggctgata ccaataaata aaacacatcc
    56821 aatcaatgag ccaatgattc ggtctactgc tcgttctttg aaaccaatcg acatcaatcc
    56881 atagctagat acaatagaag aaaatgcaaa ccctgcccac atcaatcgct gaaaagggac
    56941 atactctcct gcaacgatca aaagactaat gccaaatgca tagatgagca tccaaatttt
    57001 ttcctgcgaa tacatgcctt tcaaaaaaat ctctttaaac aagcttttgt ctttgttctt
    57061 ttctcgatgt tttctgtaaa ggagaactga aaaccaacaa aaaaacaaaa ataataagct
    57121 acttgtttgt gtaaagaaat tcttgttcaa cgaatcttta ggtaacgaat aaacaataaa
    57181 gagatatgaa aagccgtaca aagaagcatt ccccattttg ggatcactag cggttgccat
    57241 taatatgctg cttagtaaaa taaaatgaat caacatgccc ataactgacc atttgatcag
    57301 ctggacatac ggtgctacta atagtgagaa catgacgatt gctaaaccta tgatcgaatg
    57361 ggaaatctta taaccaaagt caacaaaacg aatactcatc aacatacaga ataaaaccac
    57421 agcgtatggt ttatgcttcg attcaaataa tgttgtaatt ataatgataa aacaaatggc
    57481 aaacaatacg atgaataatg atcgtaaaaa caatgaacaa atatacatgc acttttcttt
    57541 tttagaagct gcttctcgta ttttttgttt taaaataaac ggatctagtt gtagagactg
    57601 ataaaaatcc acctgttgtc gtcctttctt tttactttta ttttttacag tcatctatga
    57661 caggttgtaa atactatgga acatcatatg gcgttgtcat tttcttgtca actatttttc
    57721 ctattcatgt ttttataaaa aaacatatcg ttttcttgta tgattaaatc accacaaaat
    57781 aaacaactga gagaacgata tgctttatga atggttctat caaaaaaatt ctgagatcaa
    57841 tagacaaaaa tttgatgatt acagaggtct cttacgaaac cttacagaag aaaaaaacat
    57901 tgatcgttgc tgcagttctc ttccctgctc catgtgtctg tagaaattgt ggttctgctg
    57961 tggtagatgg aaataggaaa ttaatggtgg tgaaaaacaa gaagaaggaa accattgtcc
    58021 actttgaata atataatcat atgccaatgg ttatacgcct aaaaaagcag cgctatacct
    58081 gtaaaaactg tcgaagccat tggaacgctc aaagttattt tatccgtcca aggcactcga
    58141 tttcaaatca tgtcagacat aaaatcactt ctttactgac tgaaaaagtg tcgttatttt
    58201 ttatttcgaa aagttgttag gtatctttga caaccgttat tcgcacattg aaagagttga
    58261 gaagctattt accaaagtct tccaaaagaa ttctgtcttg agtgttgagg gttgtgaatt
    58321 tcgttctcac gtttccgttg aggataaact gagttttatt tccgcggatg gcgagacaga
    58381 aaaattaatc gagaaaattt acctacacaa aaaattcctc gattaacaaa ctatttcctt
    58441 agctgcacta atcctaaaga aatagaattc ttagttacag acatgaacgc cacctacttt
    58501 cagctcacca aacatgttct accaaatgcg aaattggtga ttgatcgatt acttggtttt
    58561 tccacgcctt tcaaggaggc gtaaccttta ttcacgagtt ggttgaagct ttccgagaca
    58621 aaagacccga cttgtttttc tccttattga caaagagcca ttaaaactag agaaaaaatt
    58681 acaactgatc gctgattatt tgtagaaaga aaatcaaagt attacccaat aaacttgagt
    58741 cattaggcaa aaaacactgc gaaactcaag aatgattttc gcagtgtttt tgtatatttt
    58801 ttattaacta gtattactac aaaggtttat ttttcacttc tcaacgcagc acaaaattgt
    58861 ctttacttat ttactggttg ggttcaacct tctctactcc gatactaata tttgtttgta
    58921 taccccttct aaaatcggta gtttccattc aattgatggg tactagttga ttttaaaaac
    58981 tatgcttatt caatttttta ttttagctca tatatttcgt ttctttctaa attttatact
    59041 gatgaaaaca agtagcacac ccaatattga caatataaac tggctaatga tggtttctcc
    59101 agtttttgga agatgcttat ttccactgct tgttggattg tttcctctta tatctgagct
    59161 atcagcaact tttctattct cttttgttaa aaagatcgcc acttcttgtt ctttttcgat
    59221 cttgaaagtt actggtgtcg catccaattc ataccccgtt ggcgcttgag tttctaccag
    59281 ctgatatgct cctggtgcta agccatctat cgccagtttt ccatctgctc ctgtggttag
    59341 acctgactgc agaacggttc cattggcatc ttgtaactca aaaacagctc cttgcaggac
    59401 ttctccgctt tggtcatcga tctttgtcaa cacgacaccg cctggtgtaa gtcgattttc
    59461 tttcgtcaat tctaccaccg ctgtctgact tctttcgatc tcaaactcga ttggtgtcgc
    59521 atccaattca taccccgttg gcgcttgggt ttctaccagc tgatacactc ctggtgctaa
    59581 gccgtcaatc gccagttttc catctgctcc tgtggttaga cctgactgca gaacggttcc
    59641 attggcatct tgtaactcaa aaacagctcc ttgcaggact tccccgcttt ggtcatcgat
    59701 ctttgtcaac acgacaccgc ctggtgtaag tcggtttgct ttcgtcaatt ctaccaccgc
    59761 tgtctgactt ctttcgatct caaactcgat cggtgtcgca tctaattcat accccgttgg
    59821 cgcttgagtt tctaccagct gatatgctcc tggtgctaaa ccgtcaattg ccagttttcc
    59881 atcttctcct gtagttagac cggtttgtag cgtttctcct tctcggttct gtaactcaaa
    59941 aacagctcct tgcaggattt ccccgctttg gtcatcgatc tttgtcaaca cgacaccgcc
    60001 tggtgtaagt cggttttctt tcgtcaattc taccaccgct gtctgacttc tttcgatctc
    60061 aaactcgatt ggtgtcgcat ctaattcata ccctattggc gcttgagttt ctaccagctg
    60121 atatgctcct ggtgctaaac cgtcaattgc cagttttcca tcttctcctg tagttagacc
    60181 ggtttgtagc gtttctcctt ctcggttctg taactcaaaa acagctcctg caggatttcc
    60241 ccgctttggt catcgatctt tgtcaacacg acaccgcctg gtgtaagtcg gttttctttc
    60301 gttaattcta ccaccgctgt ctgacttctt tcgatctcaa actcgat
//
LOCUS       DACDLM010000010        57159 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.010, whole genome shotgun sequence.
ACCESSION   DACDLM010000010 DACDLM010000000
VERSION     DACDLM010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 57159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57159
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.010"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(59..187)
                     /locus_tag="IV356_000631"
     CDS             complement(59..187)
                     /locus_tag="IV356_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAP9014345.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="IV356_000632"
     CDS             complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="IV356_000632"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAP9014346.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(1674..2729)
                     /locus_tag="IV356_000633"
     CDS             complement(1674..2729)
                     /locus_tag="IV356_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAP9014347.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="IV356_000634"
     CDS             complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="IV356_000634"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HAP9014348.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="IV356_000635"
     CDS             complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="IV356_000635"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HAP9014349.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="IV356_000636"
     CDS             complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="IV356_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HAP9014350.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="IV356_000637"
     CDS             complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="IV356_000637"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HAP9014351.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="IV356_000638"
     CDS             complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="IV356_000638"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HAP9014352.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            10491..12050
                     /locus_tag="IV356_000639"
     CDS             10491..12050
                     /locus_tag="IV356_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HAP9014353.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(12161..14092)
                     /locus_tag="IV356_000640"
     CDS             complement(12161..14092)
                     /locus_tag="IV356_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAP9014354.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="IV356_000641"
     CDS             complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="IV356_000641"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAP9014355.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(15021..15773)
                     /locus_tag="IV356_000642"
     CDS             complement(15021..15773)
                     /locus_tag="IV356_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP9014356.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(15932..16141)
                     /locus_tag="IV356_000643"
     CDS             complement(15932..16141)
                     /locus_tag="IV356_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014357.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(16152..17480)
                     /locus_tag="IV356_000644"
     CDS             complement(16152..17480)
                     /locus_tag="IV356_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014358.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            complement(17845..18432)
                     /locus_tag="IV356_000645"
     CDS             complement(17845..18432)
                     /locus_tag="IV356_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HAP9014359.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="IV356_000646"
     CDS             complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="IV356_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HAP9014360.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(20012..21301)
                     /locus_tag="IV356_000647"
     CDS             complement(20012..21301)
                     /locus_tag="IV356_000647"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HAP9014361.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(21455..22387)
                     /locus_tag="IV356_000648"
     CDS             complement(21455..22387)
                     /locus_tag="IV356_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014362.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(22544..23203)
                     /locus_tag="IV356_000649"
     CDS             complement(22544..23203)
                     /locus_tag="IV356_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HAP9014363.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="IV356_000650"
     CDS             complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="IV356_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HAP9014364.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(24244..24534)
                     /locus_tag="IV356_000651"
     CDS             complement(24244..24534)
                     /locus_tag="IV356_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014365.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            24944..26749
                     /gene="glmS"
                     /locus_tag="IV356_000652"
     CDS             24944..26749
                     /gene="glmS"
                     /locus_tag="IV356_000652"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HAP9014366.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(26821..28176)
                     /locus_tag="IV356_000653"
     CDS             complement(26821..28176)
                     /locus_tag="IV356_000653"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HAP9014367.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(28200..29369)
                     /locus_tag="IV356_000654"
     CDS             complement(28200..29369)
                     /locus_tag="IV356_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014368.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(29366..30253)
                     /locus_tag="IV356_000655"
     CDS             complement(29366..30253)
                     /locus_tag="IV356_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HAP9014369.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="IV356_000656"
     CDS             complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="IV356_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HAP9014370.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            34320..34841
                     /locus_tag="IV356_000657"
     CDS             34320..34841
                     /locus_tag="IV356_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAP9014371.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(35540..36105)
                     /locus_tag="IV356_000658"
                     /pseudo
     CDS             complement(35540..36105)
                     /locus_tag="IV356_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36284..36940)
                     /locus_tag="IV356_000659"
     CDS             complement(36284..36940)
                     /locus_tag="IV356_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014372.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="IV356_000660"
     CDS             complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="IV356_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HAP9014373.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(38477..39475)
                     /locus_tag="IV356_000661"
     CDS             complement(38477..39475)
                     /locus_tag="IV356_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HAP9014374.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="IV356_000662"
     CDS             complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="IV356_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HAP9014375.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(40491..41222)
                     /locus_tag="IV356_000663"
     CDS             complement(40491..41222)
                     /locus_tag="IV356_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HAP9014376.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            complement(41226..42491)
                     /locus_tag="IV356_000664"
     CDS             complement(41226..42491)
                     /locus_tag="IV356_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HAP9014377.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="IV356_000665"
     CDS             complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="IV356_000665"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HAP9014378.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="IV356_000666"
     CDS             complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="IV356_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HAP9014379.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            47833..49335
                     /locus_tag="IV356_000667"
     CDS             47833..49335
                     /locus_tag="IV356_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP9014380.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            49337..50074
                     /locus_tag="IV356_000668"
     CDS             49337..50074
                     /locus_tag="IV356_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAP9014381.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="IV356_000669"
     CDS             complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="IV356_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HAP9014382.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="IV356_000670"
     CDS             complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="IV356_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HAP9014383.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="IV356_000671"
     CDS             complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="IV356_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HAP9014384.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="IV356_000672"
     CDS             complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="IV356_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HAP9014385.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEEKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(55574..56740)
                     /locus_tag="IV356_000673"
     CDS             complement(55574..56740)
                     /locus_tag="IV356_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HAP9014386.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMRLMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYRDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            complement(56756..56983)
                     /locus_tag="IV356_000674"
     CDS             complement(56756..56983)
                     /locus_tag="IV356_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HAP9014387.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
BASE COUNT        15681 a        12459 c        10029 g        18990 t
ORIGIN      
        1 taaaaagact aagaaacaat aacaaaagtt aacacttctt agtctttctt tagcacgtct
       61 atttattaaa gattttaggg ccttttctca tgtttttacg atcattctta ggtgtttcca
      121 tttgtttgga tcggcctcca ccttgtttct ttttgatcaa ttctttcatt ttttcttttt
      181 ggtccatttt tattctcctt taacgaatga agcgactaat tcgatatgat gggtttgcgg
      241 gaaaagatct acaggctgaa ctttcttcac ggcataacct gcttctgcaa ataacttagc
      301 atctcttgca aaagttgccg gattacatga gatatagacg attcgttctg gtgacatttc
      361 gattgctgat tcaataaaat gatgatctaa tccttttcgt ggagggtcaa ctacgatcac
      421 agatggtttg atcccttttt cttgccattt tttcataact ttttctgctt ttccgacttc
      481 ataatgaaca ttttcgattt tattatttaa agcattgaac tgtgcatctt caattgcttc
      541 tggaataact tccatcccat acaccttatc cactctgtct gctaaagaca agccaatcgt
      601 acctattcct gaataagcgt cgatcacaat gtctttttta tctaactcgg caaactcgat
      661 ggctgtttgg tacagatact ctgcttgttg agtatttact tgataaaatg actttgctga
      721 gattcgatag gtttttccta atagctgatc ttcgatatag tctctgccat ataaaacttt
      781 ttctttgtct cctaaaatca catttgtttt ttcttcattg atattttgga tgaccgaaac
      841 cacttctggc aattcttcat gaatagcttc agcaatttcc ttggatttaa agaatttttc
      901 tttacgagta actaaaacga ccatcatttc atgggaataa tgaccacgac ggataatgat
      961 gtgacgaagc tgtccttcat ttttttcttc attatatcct cgtacttgga accgttgcaa
     1021 gatatctctg actactttga ttgcttgatc gatgacagga tcttggatat aaaaatcttc
     1081 gatagggact agatcatggc tattcttttt gtaaaaaccg gtggctaact gtccatcgat
     1141 acggcgaaca gggatctgtg ctttattacg gtagccgaat ggttctgcca ttccgaccgt
     1201 tggaagtaca ggaacttctg gcatcttagc aatcttcgcc attacatgct ctacttgttt
     1261 ttgtttgaag acaagctgtt gttcatactt caaatgggct aaaggtgcga tacctatgcg
     1321 aagtaatgca ttgttttcta caggctgacg atcaggtgat tgtgtaataa atgtttcgac
     1381 ttttccatat ccaaacttat tgcctgcttt tactactagt atttctactt cttctccagg
     1441 gagtgcattt tcgataaata atggataacc atcgattttt gctaccccca ttccttcata
     1501 actcaagtcg acgatttcga ctgtatatcg ttcgtttttc tttactattt gctgttctgt
     1561 catattttgc tcctttaagc ctatttttca atcctactga actctactat aaatcagcta
     1621 attacacaac taaaaccggc actgacctta ctacgttcag caccggcttt tgattaattc
     1681 ttttgattag gtgtttcgtc tgctattttt ccgtcaccgt cgatatcttc atccgttaaa
     1741 cgttcgactt cttttacgaa ttctttgctg acaacctcta attcttcttc atctgtacct
     1801 gtgattgctt catcaggaat ctgatcggta ttggcaaaga actcaatgtg ttgatgaaga
     1861 ttttggaaat gcatcggtgc ttccccgccg tattcaccat ctaagttgat cattactggt
     1921 cgattgatat catcttctgt ttcaacgaac aaactgcttg ttttggtata gattattctt
     1981 ggatcatcga catgtcgacc gccattcagc atgagtgctg caatatgcaa gatctcaaag
     2041 atatttgctg tcttcacaat gattaaagaa aacttcccat catccaattt ggcatctggc
     2101 gcgatctgtt cgaatcctcc aacagagttc gtcagcccta ggaaaaacat cgaagcattt
     2161 ccgatatatt ccccttcatc atacttcaag cgcattttga ttggctttac tcgagggagc
     2221 atctctgctc ctttcgcaag ataagcaaga taaccaaaaa tactctttag ttctgatgga
     2281 acttcataag tcaattctgt caaatagcca cctgcagcga tattgatgaa gtaactgtta
     2341 tcagaaaggc cgatgtccat ttttacggtt tggtgttttt ttatcacttc tgctgctgct
     2401 ttaatattat ctctaggaat ttttaatgct cgagcatagt cgttcgttgt accagctggg
     2461 atgatggcca ttttaggacg gtgttcaagc ggagcgattc cattaaccac ttcgttgatt
     2521 gtgccatcgc caccagctgc cactactaga tcaaaaccta gttctgcgac tctacatgct
     2581 tcattcttgg ctgaatctgg ttctggtgta gttgcatagg cgctggcttc aaatcctgct
     2641 tcttctaatg cctgtaggat atccgccaaa ttttttttca ataattcttt tcccgaggtg
     2701 gggttataaa ttacgcgtgc ttttttcatt ttcagcctct atcgtttcgc taattcatct
     2761 ttaagtagct tattcacgac accaggattt gcttgtcctt tagttgcttt catgatttga
     2821 ccgactagga agccaaccgc acgatctttt ccatttttga aatcatcgac agattgttgg
     2881 ttgttatcca aaatttcatt aatgattggc agtagtttgt tcggatcaga taattgcacc
     2941 caaccatttt tttcaactac ttcttgggct tctccgccat ttgtgatcaa ttcacggaag
     3001 acttttttgg cgatttttga gctgatcgtt ccatcggcga tcaaacgaat cattcctgct
     3061 aagttctcag gtgtcaattt tgtctcagct aattccagtt tctcactgtt caagtaagca
     3121 gaaacttcac ccatcaacca gttagatgct tgcttggcat ctgcaccatt ttccaaaaca
     3181 gcttcaaaaa aatcagacat ttcttttgta agtgtcaata ccattgcgtc atactctgga
     3241 agtccaaact cacggatata gcgttcgcga cgagaagctg gcatctcagg caaactagct
     3301 tttacttttt gaatccattc gtcatcgatc acgaatttcg ggatatcagg ctctgggaag
     3361 taacgataat cactagaccc ttctttgaca cgcatcaaaa ctgttttatt cgttgtttcg
     3421 tcaaaacggc gtgtttcttg ttggatttct cctcctgaaa gaagaacttt tgcttgacgt
     3481 ttttcttcaa aagctaaacc ttttttcacg aaagataaag agttcaagtt tttcaattct
     3541 gctttcgtac cgaactcttc ttgtccataa gggcgaagag aaatattggc atcacagcgc
     3601 atagagcctt cttccatttt cacatcgctg acttctgtaa attggataat tgatcgcaat
     3661 gcttctagat aagcgtatgc ttcttctggt gaacgcatat cagcttcaga aacgatttcg
     3721 atcaaaggcg tgccttgtcg gttcaaatca acgtaagaat aaccgccaat accatgcatg
     3781 ttttttccag catcttcttc taaatggaca cgttcgatcc ggattttttt ctttttacct
     3841 tctacttcga tttcgatcca tccgtcatga ccgattggtt gatcaaattg ggaaatttga
     3901 tatgcttttg gattatctgg gtaaaagtaa tttttccggt caaaatgagt atctttagag
     3961 atttcacagt ttaatgccaa agctgctttc atcccgaatt ccagcgcagc tttattcatt
     4021 actggcagca cgcctggata accccagtcg atcacgtttg tattgctgtt tggttctgca
     4081 ccaaaatgag ctggcgctgg agagaaaatt tttgagttgg tttttaactc gacgtggact
     4141 tctagtccaa tgactgtttc aaaattcatt cgtctttccc tcctaaaata gctggttgtt
     4201 gtttatggaa ttctgttgct tgttcaaacg catatgccgc ttgatacatc gttttttcat
     4261 caaaataatt accgatgatc tgcaatccaa ctggtaatcc ttctgataaa cctgccggta
     4321 cagacatacc tggaagtcca gccaagttga cagggatcgt taagatgtca ctcatgtaca
     4381 ttgtgattgg atcgttaatg ttctcaccga ttccgaatgc aactgttggt gaagatggcc
     4441 cgatgatcaa gtcataatct gcaaagactt tttcaaaatc tcgtttgatc aatgtacgga
     4501 cttgtcccgc ttttttgaag taagcgtcat aataaccagc acttaaggag aatgtaccta
     4561 acatgatacg gcgttttact tcttcaccga atccttctga acgtgagttg acatatacat
     4621 catctaatga tttcacattt tctgagcgat aaccgtagcg gataccatcg aatcgttgca
     4681 agttggaact tgcttctgat gaggcaatga tataataaac agccacaccg tattttgaat
     4741 gaggcaagct gacttcttcc acaacagcac ctaatgaacg gaatgtttct gctgctttca
     4801 atacagcttc ttttacgcca ggggccacac cttcgcctaa gtattcttta ggtaaagcaa
     4861 tcttcattcc tttgatgtcg cctgtcagtc cctctgcaaa atcaggaact gaaacgcctg
     4921 aagaagtacc gtctttttcg tcataaccgc tgatagctgt caatgctaat gcattatctt
     4981 tcaccgtacg ggtcattggt ccgatttggt caagagatga agcaaaggca atcaaaccaa
     5041 aacgtgagac acggccataa gtaggtttca tccctacgat gccgttaaaa gctgctggtt
     5101 ggcggatact tcccccagta tcactaccta aagaaactgg aatttgtcca gctgcaactg
     5161 ctgctgcaga accaccagaa gagccaccag gtacttttgt tgggtcccaa gcattttttg
     5221 ttttcttgaa ataagaagtt tctgtacttc cacccatagc aaattcatcc atgtttagct
     5281 taccaacagg gatcatatct gcttgataga ttttatccat gaccgttgca tcataaattg
     5341 gttcaaaatt gtaaaggatc ttagatgcag cggttgtcaa gatatctttt gttacgatat
     5401 tatccttgat accaattgga ataccagcaa ggacgttgct ttcatcaatc cctttttcat
     5461 ctaaagcttt tgcctgttcc aatgcttttt cttcgttcaa tgtaatgaat gcttcgacct
     5521 caggctctgt ttctttgatt cgttcaaatg ttgcttttgt caaatcttgt acagtgattt
     5581 ctttcgatac aagcatatga tgcagttctt ctagagaacg attgtgtaat tctgtcatta
     5641 tgcgccagcc tccccattat cgatgattgc gggtactttg ataaagccgt cttctgtttc
     5701 cggcacattt ttcaataatt catcgcggtt ccatccagct tgcgcccgat cttgtcgcat
     5761 cacgtttact gtttcaacca cattcgacgt aaatggaaca ccttctgtat ctacttcttc
     5821 cagcatttca accatatcga tgattttacc taattggtcg gtaaaacttg caagttcttc
     5881 atctgcgaac gcaagttttg ctaatttggc aacgtgtttc acttgttctt cactaatcgc
     5941 catactaccc cttctttcta aacgagttaa aaactttgct ctctatttta acacaagagt
     6001 gccgtgtctg aaattgttta ttgaaatttg tctgaaaaaa ctcatttttc attcttctac
     6061 tgagcgactt ttagccaatg catctgccat ttgatcttct gtccaaactt cgattcctaa
     6121 ttcttgtgct ttggtcagct tgctgccagc atcttctcct gctaccacga tatccgtttt
     6181 tttcgatacg ctaccagtca ctttcccgcc aagattttcg atcgtctctt ttgcttcttc
     6241 acgagtaaat cgtgttagtt taccagtaag gactactgtt ttttctttaa aaggagactc
     6301 gacttcttgc aattgggcat ttcgaagccc tttgtattcg aaattgacgc ctgcttgttt
     6361 taattcattc atcaattcat ggacttcttc gttactgaaa taagtgacta cactgtcggc
     6421 aatgatatca ccgatcgtat caagcgcaat aatcgactca tagtcacttt tactcaatgt
     6481 ttctagatca ccgaaatgtt ctgctaaaat ttttgctgct ttcgctccga catgtcggat
     6541 tcctaacccg aaaatcaacc gctcgaccga attatctttg ctgttgtcga ttgctgtcaa
     6601 aatattattt gctgattttt cttttatttt gtccaacgtc aataactctt cttctgtcaa
     6661 tttgtaaaga tcagcaacat ctgctactag ttttttatca tacatctgtt ctagtacgcg
     6721 cggccccaac ccatcgatat tcatcgcatt tcttgaaaca aagtggttca aaccttcttt
     6781 catttgagca gggcatttag gattgatgca ccgtaaggct acttcttcat ccaaatggac
     6841 aagttcactt ccacaaactg gacaatgtgt aggcaattgg tattcttcgc tgtctttagg
     6901 tcgtttatct aacacgactt gcgaaacttc tgggatgatg tctcccgctt tataaatcag
     6961 aactgtatct ttcaagcgga tatccttcaa cttaatataa tcaccgttat gcaggctggc
     7021 acggcttact gtcgttcctg ctactcggac tggtgtcatg atagctgttg gcgttactac
     7081 ccctgttcga ccgactgtcc attcgatgtt ttcgattagc gtttcaactt cttctggcgg
     7141 aaacttgtaa gctgctgccc atctcggtgc tttgacagta aaaccaagtt gatcttgtag
     7201 cgagaattca ttcactttga tgacgattcc atcgatttca tagggcaaat ccacacgttt
     7261 gtcatgatat tcttcaatgt atgaccacac ttcatcaatc gaatgacata gacgtttttc
     7321 ccgattcgtg tggaatccaa ttttttctag ctcttctagc gcatcatact gggtttttgc
     7381 ttgcatagga ccgaaatcag ctactgtgta taaaaaagtg tccagatttc ttttcgctgt
     7441 gattttagaa tctaactgac gcaaagaacc agctgcggcg ttccgaggat tcgcaaagat
     7501 atcttttccc tctgcttctc tgtcttggtt caattggaca aatgaccgtt ttggcatgaa
     7561 acattcgcct cttacttcga tgttcattgg ttcttttaat ttgattggga ccgaccggac
     7621 agtttttagg ttttcagtga tgttttctcc tacagttcca tccccgcgag tcgcacctct
     7681 cacgaaattt ccatcttcat aacgcaaaga aacggaaagt ccatctattt ttagttcaca
     7741 gcaatagtca actacacgtc ccactgcttt ttgtacacgt tgatcaaaag ctatcagctc
     7801 ttctttgctg aaaacgtcgt tcaaactgta aagcggaata tcatgagtga ctttttcaaa
     7861 accttctaat acttttccgc ctactcgttg agtgggagaa tcagacgtga tcaaatcagg
     7921 atattgttcc tcaattgcta ctaattctgc gtattcttta tcataaacat agtcttccac
     7981 tgttggttta tcttctacgt agtattcgcg agaccattgg ttcagtcttg tacgaagttc
     8041 ttctgctcgt ttagcagctt cgtcaatcgt catttcatgt tccatcattt accctccact
     8101 actaagcttt ttcaattggc gcaaaggcag ccaaaagacg ttttactcct tgacttggga
     8161 aagccacatc tagttctaga tccttcgacg tcccgcttac tcggacgact gttcctagac
     8221 cccatttttt gtgtttgact ttatctccag gtttccagct gttattttcc cctccagtag
     8281 cacttttaga gggaacaacc gctgtctctg gctgtttata gctatatgct gtttttttag
     8341 cgaatacagg tgttttttta ggcgtaggac gcatgccttc gatttccagt aactcctgat
     8401 cgatttcttc tacaaaacga gaaggtcggt tatattgcgt ccgtccatat aatgttctgg
     8461 agaaagcatt tgttaaatac aacgcttctt ctgctcgcgt gatccccaca tatgcgagac
     8521 ggcgttcttc ttccagttcg ctttcttcca tcaatgctcg agataaagga aaaaccccct
     8581 cttctagacc aatcaggaat acaactggga attctaatcc tttggctgca tgcaaagtca
     8641 tcaatgtcac ttgggaagca tcttcttcta aattgtcaat atcggaaaca agtgccagat
     8701 catttaagaa gaccgttagt ttttcttctg gtgcatcagc gtcttcttca ttttgctgtt
     8761 cgaattgttt gtcgaattct tgtgtgaccg ttaaaaattc ctccaagttt tcgatgcgtg
     8821 cttgtgcttc taatgtattt tggattttta agtcttctag atatccgcta cgatccaaaa
     8881 cctctttcgt caattctgtc actgtcaagt atgggatcat ctgagtgact tcttggatca
     8941 tctctccaaa tgcacctaat tgctgtcctg cttttccacc gatatttgcc agatccacat
     9001 tttgcgctgc ttcaagcagt ggccattcat gaagagaagc aaaactgcgt agtttttcga
     9061 tagatcctgg tccgatgcct cgtttgggcg aattaacgat acgctcaaaa ctgattgaat
     9121 cttgaggatt tgccagcaca ttcaaatacg ctaaaatatc tttgatttct ttacgatcgt
     9181 agaacttgtg ccctccaacc attttataag gaatatttgc tttcaacaga gtttcttcca
     9241 ttacacgaga ttgtgcgttc gtccggtaca agatggcaaa gtcgccgtaa ttccgatgat
     9301 tgcttcgaat ctcttcttgc atccgatcta cgataaaacg ggtttcgtct cgttcattat
     9361 ctgcacggta gtaagtgatc ttgtttcctt ctttgttttc tgtccacaag ttttttggtt
     9421 ttcgattgct attgttttca atgacttggt ttgctgcgct aaggatgttt ttcgtggagc
     9481 gatagttttg ttctagcaaa attactgcag catctggata atctttttca aaatccaaga
     9541 tgttctgcat atctgcaccg cgccagccgt aaatactttg atctgcatct cccacgacgc
     9601 acaggttcct aaatctacct gccaataaat tgactagcgt atactgtgcg tgatttgtat
     9661 cttggtactc atctacatga atataatgga atttgttttg ataatatgtg agtgaatcag
     9721 gatgttcttc aaataatcga atcgtattca tgatcaggtc gtcaaagtcc atacattgat
     9781 tatattgaag ctctttttgg taagcagcat aacattttgc cgcaatctct tcgtaataac
     9841 tgccttgcat ttttgcaaaa tcctgagggg tctgcaggct gttttttgct tgagagattg
     9901 ttcctaatat acttcgagga tcatattttt tcggatcaat gttcagttct tttagtatcc
     9961 gtttcatcaa ggtcagctgt tcagaagaat cgatgattgt aaagttccgg ttatacccga
    10021 taaaatcaac atctcttctt aaaatacgca cacacatcga gtgaaaagtc gatacccaga
    10081 catcttcgcc tccagatgcg agaatcgcat tgacacgttc tttcatttct tttgcagcct
    10141 tattggtaaa agtaatcgct aggatgttcc aaggattgac ttctttttcc tcaatcaaat
    10201 aggcaatgcg gtgtgtcagc actctcgtct ttccacttcc tgcacctgcc attagcagta
    10261 atggtccgtc agtgtgaaga acagcttctt tctgacgggg gttcatcccg tttaataatt
    10321 cagctttgga tgacattaac aacatccttt cttttatcaa tcttgttaat tatagcattt
    10381 tcttggcttt cattaaacta gctagttcaa aatcatttgt ttctttttat ggatttttcc
    10441 ttgtcaattc gttgatttcg cgctaaatta aaagaaagcg aggcgtttga atggaaaaaa
    10501 aaggaaaaat caagaaatta gataagactc agatatattt tattctaaaa ggaatatttg
    10561 ttggactgct gacaggaatc gtcgttagcc tgtttcgatt atctatcgaa aagctaagcg
    10621 atttagttcg aagtatctat gaaatgagtc gggaacagcc gatttactta attggcctag
    10681 ctatttgctg catccttgca gcatttttcg tgggttatct ggtcaaaaat gaaccggata
    10741 tcaagggaag cgggattcca caagtagagg gacagcttcg cggggaatta tcaatgaact
    10801 ggttctctgt tttatggaaa aagttcattg gcggtgtact ttcagttggt gcgggccttt
    10861 ttctaggtag agaaggacct tctatacagc ttggcgcatc cattggacaa ggagctggac
    10921 aattgtttcg gagtccatct tcagaagaaa agattttaat ttctagcggt gcaagtagcg
    10981 gacttgcagc agcattcaat gctcctatcg caggattact ctttgtttta gaagaaatcc
    11041 atcactcctt ttctccactt gtttggctga catcatttgc ttcagcaatc actgctaact
    11101 tcgtctctct ttactttttc ggcttgagac ctgttttata tctaggtgac cttccttctt
    11161 tgccgttgaa atattatggt tccttagtga tcttaggagt acttctaggc atcttaggtt
    11221 ttatttatca gaaggtcttg ctggctttgc caaaatttta caaccgattg cctttaccag
    11281 cttattttca cgggttcgtt cctttcttgc tgattttgcc aattggttat ttatggccta
    11341 gtactctagg cggaggcaat caaatcgttt tagcttttgg acatgcttcc ttgccaatca
    11401 ttatgattat cggtttgttt gttcttcgat tcgttttttc catgatttct tacggtggtg
    11461 gtcttccagg ggggattttc cttccgatat tgacattggg ggctttaatc ggtagctttt
    11521 atggaaacat tatggttgat ttcgggatgg atccaatcta catcaaggat tttgtcgtta
    11581 ttgccatggc tggttatttc acagcgattg gaaaagcacc gctgacagca attattttag
    11641 tgacagaaat ggttggctct cttaatcatc tgatgccttt aggattggct gctcttgttg
    11701 cttatatcgt caatgacctt ctcggcggta atccaattta cgaatcatta ttggaacgtc
    11761 tacttggaaa tactcagacc gcctcactaa aaggtgcaag gacaactttt gattttccag
    11821 taacggcaga gagttcttta gacggattaa tggtacgaga cttcaattgg cctaaaaata
    11881 tgctgctaat ctctatacgc agaggaaatc aggaaatctt gactcacggt gatacgatca
    11941 tgaatgtagg agatattttg gttatcttga ctgatgaagc aaacttgcca agaatcaagc
    12001 aggaaatcga ggctaaatct tctatcacaa atttgaagca atcattttaa cgaacatgga
    12061 aaaactattt tacaacaact attcatctac actacttgat tctatatgat tctataaaaa
    12121 aagaagagac tgggaaaaac cagcctcttc ttttttattt ctatgcttct gctgctgcag
    12181 gagcttttct caataaacca taaatcacac cagatacgac tgctccgata gcaataaaca
    12241 ccaaatacat gaccgggtga ctcagtaaga atacaacgaa aatcccgcca tgaggagcca
    12301 gtaatttgat cccgaaagct ccgactaatc cgccagttaa agcagaacca ataataaaac
    12361 ttggaatggc acgaatcggg tcagctgctg caaatggaat cgatccttcc gtgacaaacg
    12421 atagtcccat cacgatgttc gtcaaaccag catcttgatc tgttttgctg aatttattct
    12481 taaacaaacg tgtagcaacg aaaattgcca atggaggtac cattcctcca gccataacag
    12541 aagccatcac gacacttccg ccagttgcaa cagtcgtagc taaagttgct gtaccaaaca
    12601 cataagcggc tttgttgatt ggaccgccta aatctgccgc catcattcca gctaataatg
    12661 caccaagtaa agcagcattc gaaccactca tacttgtcaa gaaaccgttc aatgcatcat
    12721 tgattgcttt catagggaca ttgaccagca acatcaagaa accagtaatc agtaagccaa
    12781 acactggata aaagaggatc gttttaattc catccaatga ttttggtaag ttcttgaata
    12841 atttacgtaa aaatacgatg acataaccag ctaagaatcc accaatcagt gcacctaaga
    12901 atcctgcacc gcctgtatta gctaatgcac cagcagcaaa tccaacgatc aaaccagggc
    12961 ggtcaccgat acttgaagca ataaatcctg ctaataccgg cagcatgaaa ccaaatgcag
    13021 cttgtccgat ttggttgaac cagctagcag cttgattgta attccctaga tttgataatt
    13081 gatcatgtgg cacgccaata aattggtcga tcatgaaaga aagcgcaata gcgattcctc
    13141 caccaataac gaaaggtaac atgtgtgata cgccgttcat caaatctttg taaattcttt
    13201 gtccgatagt accatccgca tttccttctt ctgaactgct ttcttttcca tcaccatgga
    13261 atactggtgc agtaccacta agggctagat tgatcagctc ttctggttta cggataccat
    13321 cactgacagg acgattgatc agttcttttc cgtcaaagcg attcatctct acttttttgt
    13381 ctgctgcaac gattacacct tctgcacggg cgatgtcttc agcagtcaat cggtttttga
    13441 ttccttctga accgttcgtt tcgactttga tctccacacc catttctttc gcttttttct
    13501 tcagagcatc ttctgccatg taagtgtgag cgatccctgt tggacaagct gtaacggcaa
    13561 caacgaattt tctttctgga tgagcagaag cttctgcagc ttgtgtttct tgttctgctt
    13621 tttcttctgc ttctttttgc tcttcagctg tttggaacaa gtcttggact tcttctggtg
    13681 tatttgcttc ttttaatttt cctacgaaat ctgcatcaat cagcaatcga gatagtgctg
    13741 ctaatgcttg caaatgtgtg tcgtttgcgc cttctggagc tgcgatcatg aaaaacagat
    13801 aagttggctg tccgtctaag gcttcataat ctactccttt ttggcttttt gcgaataaaa
    13861 ctgttgcttc tttaactgca ctgtttttcg cgtgaggcat ggcgattcca tcaccaagac
    13921 ctgtagaagt ttgtgcttcg cgggctagaa ttccttcttt atatgtttcg atatcggaaa
    13981 tccggccggc atcaaacatt ttttggacca tttcatcgat tgcgcctttt ttatcagtcg
    14041 cttgcaaatc catgatcatc gcttctttga ccattaaatc cttgatattc atgattatcc
    14101 tccttgaaac taatcaattt ttgtgatttc aacttctggc agcaactcat caatcaattc
    14161 gcgagctgcc aagtcatcag aaaaagctgt tgcgcttccg caagcaactc cccatttaaa
    14221 ggcttcgatt ggatctttcg tacggctgta agccccaata aagccggcaa tcattgaatc
    14281 ccctgcacct actgaatttt tcaatgggcg aactaataca ttcgttttat aagttccttg
    14341 ttccgtgaag agcaaagcac cgtctccagc cattgagatc agcacattct gtgccccttc
    14401 agctagcaat tttttaccat acggaatgat ttcttctaca gattggaagg ttgtattgta
    14461 aagctcagct aattcgtgat tgtttggttt gatcaacaat ggtttcttaa caagtgcatt
    14521 ttttaggtca tcacctgttg tatcaatcac gaaatctgca cctttttctc gaatgatatc
    14581 aatcagttct tgataaaatc cttttcgcag gctagccggc gcgcttcctg acaatacgac
    14641 gatatctcct tgtcctactg ttcctaatgc ttgcttcaac tcatcgattt cttcatctga
    14701 aatagatggg cccaaaccgt taatttcagt ttcagtatct gattttagtt tgatattgat
    14761 tcttgtatct tcttttacgg ttgtgaacaa agactggatt tgttcttttt caagccactt
    14821 cgaaataaat tcgccagtga accctcctaa aaaccctagt gctgtagatt gagaatcgat
    14881 ccgtttcaaa atacgggaaa cattgatccc ttttcctcca ggtaacttga agtcttcctt
    14941 cattcggttc aaatcgccta gttttaaccc atctacgcgt acgatataat caattgatgg
    15001 attaagtgtt actgtgtaaa tcattgtatt gcctccttaa ttgttgtctt ttcacggaat
    15061 tcattaacga attctaatgg acaacgctcg gttatgatcg tggctgcttc caaaggtgca
    15121 acagaggtga aggacaactg gttgaatttg gtatgatcaa tcaatacaaa tgtctcttcg
    15181 gaatttttca tggctaaacg tttaacagct gcctcttctg ggtccggagt cgtgaatcct
    15241 tgttcaagat gggcaccgtt cattcccata aatgctttat taaaatgaaa attttttagt
    15301 tgttctatcg cattagatcc taaaacagca ttagttgcca gctttatcgt tccacctaaa
    15361 ataatggtag caagctccaa atcaactaaa tttgccgcat gttgaacgga atttgtcact
    15421 actgtgatct gttttccttg cagaaaagga atcatttcta acgtagtaga gccagcgtct
    15481 aaataaatga catcttcgtc attaatggtt tcagctgccg atttggcgat ttgctgtttt
    15541 tcgtgaacgt ttttgagtga tttttcactc atattctgct caaaattcaa taattgctct
    15601 ttcttagctc cgccatgaac tctttctaga aacccactat tctccagctc ttgtaaatca
    15661 cgtcttatcg ttgattcaga agcattaaaa aggtttacaa gatcttgtga tttcacgatt
    15721 ttctgctgtt caagcaagtc taggattttt tgtctacgtt cctctgtaag cattttcacg
    15781 atcacctcaa tacaaataat agcatatttt ttttctactc gcaatataaa tcagtcaaaa
    15841 acgttcataa aaattataaa tcagtcaaaa aaaaataaaa aaccagtcaa aaagactggt
    15901 tttttatttt tttgtctatc atcaagccgt tttatcgttt tttattttcg cttcttgttt
    15961 ttttcatata aacagaagca ggttttcttt ccttatgaag aagataataa taaagtccca
    16021 tcccgccaaa catgaccaaa aaaccgatga ctgatcgaat aggaaaatta ggaacaaaaa
    16081 agagacagac ggataataat gatgccggaa ccattattcg ataatagagt tgtttatcca
    16141 ttttcttcac ctcatatttt ttgtaaagta atcaattgtt ctaattctcg gtaatctaaa
    16201 aattgcacac gcagatgctg ctcacctttc ttgacatcga attggatact tcgccgcttt
    16261 ttctttattc gtttgaaggt aacatcagag agtctatgtt tgatttcctt taacggtaat
    16321 tctgacaggg attctgaagg aacatagatt cttaaggata aaagatactc ttgatatttt
    16381 tcatctgtta cctctacttc tagatattcc ctaatataat aacaataagc ttcgattcca
    16441 ttatccaaag caacagtcgg atcgataact ttatagcaca tcatgcgcga gcgattctcg
    16501 tcaacccaag gaaaatacgc ctgagcattt agtgttccgc gaacacgcct ttctttataa
    16561 tctccttgtt gaatatcata actttttgtt acaaaaaatg aagcattctt tttaggaaca
    16621 ggttgcattt gtgcattctg atactggaca gattggatcg tatggtcagt gtaaatgtat
    16681 tcaacgaatg gcggtttcaa taaaccgaca ccattgtccc aagcaagatg atcaaaccca
    16741 agctggtccc taaaatagga ttgaaacatt tgattgtttg gcttttgcca gttaaagggg
    16801 tctcgataaa gctggataca tatgacttcg ttttctaatt ccttcacttt ttctacttgt
    16861 tggatgtcga gaaaaatcgg tttagggatg atttgatgat aatagcgact ataatacatt
    16921 tcccaacacg aagtgaaaca taaaccttgg taaaaaagat cgtatcctgg aaattggttg
    16981 caatcgacta ctacttcccc gttttgttgt ttcattttag gtaaatgttc gatttcatcc
    17041 tttttctcaa acaatagccg ttgagagatc tgttttgtat tgtgatagat aaactcgcta
    17101 taagctcgca tataggcgaa caccccatga gcaatcattt ttttctgaat gaagtctcga
    17161 atcaaaaatt gcttttcttt gaaaacagag atagacaata cattttttat caataattga
    17221 ttatcttcca agcgaaaact acattcgttc tcgtcatttc ctacaactaa ccaactttcg
    17281 tctcttaccg atgctagcat tattttttct tgaagctttc gaagatcata cggatccgct
    17341 tgttgtgtga aagagcggat aaatgttggc tggatcaaca gacgtgtcaa aatagcccaa
    17401 tcgcttattt cctgtttttt ttcttcttca tttaagtctg tgagctggat agtcatcaat
    17461 aatttatctt cgccaatcat tttctcacct ctttaaaatc tttttataat ttaattataa
    17521 ccaacgataa agaaaaacta aaactttatg tcttagaaac caatttggac gattacatga
    17581 tagactaagt aaaaagaaac aaagaggtgt ttacaatggg gttgaaattt gaacgtacag
    17641 ataatttaga taaacttttc gaatcatttg ctgtcgatcc ggaaaaaaca gttgcaccaa
    17701 aagaagagat cgatcgattt ctaaaaccac agccacaaaa tgaaaagaaa aaagacaaga
    17761 aacaaaagta agttaagctc aaaaaaagac ttaccagcca aacttttatg aaagagtttg
    17821 actggtaagt cttttttatt ctttttatga ttcaattgct tgttcgattg ctgcccacgc
    17881 ttcttctttt ccctgttttg taacggaaga aaagagaata aacgtgtcat tgcgatcaaa
    17941 atccaacgct tttttgattt cgctctcatg cttgttccat ttaccacgag ggatcttatc
    18001 tgccttagtg gcaacaacaa ttacagggat atcataatac ttcaaaaatt gatacatctg
    18061 gatatcttct tgagaaggct tatgacgcaa atctactaaa gaaacgaccg cacgtagctg
    18121 gtctctagtc gttaaatatg tctcgatcat ctttccccat tttgctcgct cagttttgga
    18181 tacttttgca tacccatatc ccggaacatc gacaaaatgt aatgcgttct cgatcaaata
    18241 aaaattcaat gtctgggtct ttcctggctt accggaagta cgggctaaat tctttcgatc
    18301 aatcaatgtg ttgataaaag aagatttccc tacatttgat cgtcctgcca gagctatttc
    18361 tggcaattgt gtatctggat attgttttgg tgccactgca cttatgataa tttcagcttg
    18421 atggactttc atggtctctc tccttaacaa ggtgatgaat aaagcaagcg gctgtcgcaa
    18481 aagccaaaat gacttttacg gcagcctctt ttcatcaacc cgcttttttc tctgaatctt
    18541 tatagattac tgttggctca ccagacaatt cagctgcttc ttttgtgata atcacttttt
    18601 cgatgttttc atttgaaggg atatcaaaca tcacatccat catgatttct tcaatgatgg
    18661 aacgaagtcc tcgagcaccg gtattgcgtt cgattgcttt tttcgcaatg gctctcaacg
    18721 cttcaggttc gaattcaagt tcggtattat ctagagaaag aagtttttga tattgtttga
    18781 ctagcgcatt tttcggctca gtcaagatcc gtaccagatc atctgttgtc aatttctcta
    18841 aagctgccat aacaggtaat cgtccgataa actcagggat caatccgaat tttagtaaat
    18901 cttcaggaat gatatgctgc atgacacttt cgtcttcaga aagtttttgg ttttgtgtac
    18961 caaatccaat cgtcttttcg cccatacgat tcttcacaat cgtttcgatg ccatcaaatg
    19021 caccacctac gatgaacaat atgttcgtcg tatcaatctg aataaattct tgatgtggat
    19081 gtttacgtcc tccctgaggt ggcacgcttg caacagttcc ttctagaatt ttcagcaagg
    19141 cttgttggac accttcgccg gaaacgtcac gagtaataga tacattttcg cttttacgcg
    19201 caattttatc gatctcatca atatagatga tccctttttc tgcacgttcc acattgtaat
    19261 cagcagattg aagcaattta agcaaaatgt tttctacatc ttcccccaca taaccagctt
    19321 ctgtcaaact tgtcgcatct gcgattgcaa aaggtacatt caatgttttt gctaatgttt
    19381 gtgctaaaaa tgttttacca gaccctgtag gtccgatcaa gcagatattg cttttttgca
    19441 gttcaacatc atctgtgttt tcttgtgctt gctgattgac acgtttatag tgattgtata
    19501 cggcaacagc taacgagcgt tttgcgcgat cttgtccaat cacgtagtta ttcaatactt
    19561 caagaatttc tagtggttta gggacttcag tgaattcgcg tacagcttct tcataaaatt
    19621 cttcatcaat gatttcttta cataggtcga tacattcatt acagatgtag acccctggac
    19681 cagctacgat ctttttcact tcttcttggg ttttcccgca aaaagaacag cgtacggtct
    19741 cattgctact tggattgtca tacatggtct tcacccctta acttgcaaaa agtatgcaag
    19801 aaactatcaa agactttaca gtcttttact atcataacat agtttagtaa aaagaaaaag
    19861 tgtttaacaa aggatcaact gacctatacc tttgcatttt ttactcttaa caaaaaataa
    19921 ggaactgtga caaaatcgtg tcacagtccc ttatttcgaa taaacaattt tctagaagta
    19981 gcttcttcag aaatgattta ttacttgatt tctattcttt cgcttctgtc gctgtacctg
    20041 tgatcaattc gattgctttt ttcattgtca catcatgttc cagcatatct tctgtcaaca
    20101 cgcgtttgat ttgttcgatt ggcatgttgt atgtttctga taattcttgg atttctgcat
    20161 tgatttcttc ttctgttgct tgaagatttt cagcagctgc aattgcttcg atcacaagat
    20221 ttgttcttgt gcgcatttct gcttcacctt cgaattgttt atgcaagtct tcttctgtag
    20281 aaccagttaa ttgatagtac atttcaggag agataccttg acgttgcatg ttgttcaaga
    20341 attcgtccat tgaacgatgt acttcatcat gaaccatcac gtgtggcaat tcaacgattt
    20401 ctgcgttttc aacagccata cggatcgctg cttcatcttt tgcatcgtcc gctgcttttt
    20461 cttttgtttc tactaattct ttgcgatatt tttctttcaa ttcgtctaat gttgatactt
    20521 cgtcatcaac atcttttgcg aattcgtcat ctaattcagg cacttctttt gcttttactt
    20581 catggattgt cactttgaag actgcttctt ttccagcaag atcttctgct tgataatctt
    20641 ctgggaaagt tacatttaca tctagacttt cacctgattt atgaccaact aattgatctt
    20701 caaaacctgg aatgaatgag cctgaaccta attcaagtga gtaattttcg ccttttccgc
    20761 catcaaacgc ttcgccatct acaaagcctt cgaagtcgat tactactgta tcgccatttt
    20821 cagctgcagc atcttctttg ataactaatt cagcttgtgc ttcttgttca cgtttgatac
    20881 gtgcatccac gtcagcatct gttacttcac ggtcttgttt ttcaacaact agatctttat
    20941 attgtcctaa ttttacttct ggtttcactg ttacttcagc agtgattacc cagtcttgac
    21001 ctttttccat gctttcaaca tcgatttttg gttgagaaac aggatcgatg ccagcttctt
    21061 tgacagcagc ttcataagct tctggtaata cagcattcaa tgcatcttca tataaagctt
    21121 cttcaccgta catacggttg aatacttgac gagaaacttt ccctttacgg aatccaggta
    21181 cgttcaagct ttttttcact ttattaaacg cagttgttaa tcctttttgg atttcgtctt
    21241 gcgcaatcgt aaattttaaa acaccatcat tcgtgccttt tttttcaaat gttgcagtca
    21301 tttaattccc tccgagttta gaaattcatt ttatacatca aaaacgtttc atgcatacct
    21361 ttaaatagta cactaaccct ttcaaattgt aaacatattg aatggataga atccttgttt
    21421 ttcataacat ttttatcttt ttcactgata aaatctaatg gaagaagatc atttgctgca
    21481 aaattttttc tctttttttt aaaaaatctt gtttttcatc ttctgtacct tcatacatcg
    21541 tttttcctgt acacgcctct acagtcagtt gaaaccagcg cttcgggtct tcgatgtatg
    21601 tatcatagac aggataaaca attgcagatt gcaacgtgaa ttcttcattt aacacggaac
    21661 taagcagcgc atcttcatta ccgtaacgat ctgaaaatac acataattgc tggtaacttg
    21721 cctgctgctg cggctttggc agatcttttg gtatgacttt gactaacttt tcttcaatcg
    21781 tcaaatagaa aacaggatgg cattcgttca attgcctaag tgtctccagt aattttgccc
    21841 ttgctaaaat atggacctct ggcgatacaa taagtttact cgctgtttgg ataaactcat
    21901 gataaggaag ctgttcgatc tcatcaatag acgcaagctg acgtgcaggt tccaacgaag
    21961 gaagttcctc cgatttattg tggagtgcct tgatcttctg cctctccatt tgtccggata
    22021 attcttctgc aaattggatt ttttcaatga cccgctgctc gaaagcttca taaaaatctg
    22081 tacttgctat caattttcta gcatataaaa aatcttgtgt actgattaac aagtcaaaat
    22141 aaaattcagc aaactcctca ttttgaagat actgtttttc atgcaagagt gcttgcttca
    22201 atgcttcttt tttctcgtcc aactcgtaaa gacaaaaaac aagcaggcta ttagcctcaa
    22261 agctttcttt caactcgtaa gctcgttgaa ataattcttt tgcctgctga tattgctggt
    22321 ttgctagtgc ttgttgtgct actcgcatta aattctcata tttttctgga aaatcaatcg
    22381 gcttcacgca gtgtcctcct cttgctcatg ttcagctcat gttcaatagt agcaaaacaa
    22441 aaaaagcatg acaattaaaa ataactgaag caccctctaa aagctagatt ttagatctga
    22501 cttttagaag gtgctttcaa ctgttactgc tttttattgc tcatcagctg ttgacttcct
    22561 ggttgaatgc tttgatcaga ttgatcgtaa caacacttgt attagtgaaa aaatcgccta
    22621 gatgttgctt tttctgatta aagattgctg gaagataccc taacatcagc aaaggaaatt
    22681 ttagaatgaa ccggcaagca ccttctctaa ctaaaacggt tgaccagcta agttcttctt
    22741 catcaaagct gatgactcga ataccaaaga tcattttccc aatcgtttga ccatgattga
    22801 atttcgtcaa taaaataaaa tacgctagat aaataagtaa ggctgtgaat ccgtagatac
    22861 tcagataaga atctgaaaaa ttaagccaac ctagattttt ggcaatacca agtgttaaac
    22921 gcgtaatagc tccgatacac aaaagatcga ccaagaaagc aaacattcgg ataaaaaaac
    22981 ctgcatagaa atacttagga aaatcatttg cttttggcgg ttcatttctt gtgtccgtat
    23041 actttttcca tttacgttgt ttctttttga tttcttcggg cgtcaaaggc tctctttcaa
    23101 aagagctcag taccttttgg gaaaagttgg agtcaggtcc tacagcaggc tgctgttgct
    23161 tatctttttc ttgttcctta ttttcatttg aaagctctga catgcttact cacctccgta
    23221 ataatacatt gcttttggtg attccgctgt ccctagattc tcaagaacgg ataagatctg
    23281 actagtctca gaaggcttca atccctggaa ttctgctagt ttacttccta accatgtact
    23341 agcaaaccca gatggcgtgg aagaatattc tactagttcc gcatcttcaa gctgttgttc
    23401 ctttcgcata gcttttaaag catcttcagg aaatcccaat tcatcgacta aacctacttc
    23461 ttttgcttgg acaccatcat aaatccttcc atcagcaatt tttttgactt cttcttcaga
    23521 tttattccgt ccctcgctga cgattgctac aaaacgacta tatgcgctgt cgatatatgc
    23581 ttgaagcacc gcttcttctt cttttgtctc tggtcgcgtt cctgaaccca tatctttcaa
    23641 cgctccgctt ttaactgttg tatcttccac acccagtttt tctagaagtc ctgaataatt
    23701 caatcctgac atgatcacac caattgagcc ggtcactgtt tcttctgttg caaagatttt
    23761 atctgcttga gcagaaatat agtagccacc gctagctgcc atgtttttca tgctgacata
    23821 cattgggata tcatgttctt tacgaatcgt atccaatttc ttagcgattt ccgcactttc
    23881 gtagacaccg ccaccaggag aatttacttc taaaaagata cctttgactg ttggatcttc
    23941 ttcaatcgcc ttcagttgtt ccataaaatt tttatgattg taaccttcag aagcaaataa
    24001 acctgaagac cctcccgcag caatcgttcc atctactgat aattttacga ttttttgcgt
    24061 actgtctccc tcttccaaca catttgaagc tagttcttca tccccatata accaactgtt
    24121 caatccctca atttgatcgt tttcctgagg cttagtcaaa ctagctgaaa ctaacgaaac
    24181 cacaaataat cctgcagcaa tcagaactgc tgcccaacgt ctcttattca ttctttctcc
    24241 tttctaatac aagtttttta tgacgatcac agtttctgac tgctcagaag tgtcgaaccg
    24301 ctctgctttt tcttcccgcg catacccgga aaacgactct tttgtcaatt catcttctac
    24361 cgtaaactca cgagcttcag caacttccaa ggcatcaggt gcgatttctt ggatgctatc
    24421 ccagccagta tctaaaaata ttttcgtatc atctgataca ccagctgatg cttcgaattt
    24481 ggacaattgt ttttttaaca ttcccagtgt catgatctca atttttgaat ccatttttac
    24541 tcctcctcta tccgattact ttctattgta ccgaactcct gaaaaagatg atagataaaa
    24601 acccattatt ttttgacata aaaagagcat ttgacaaagc atttgatata taccaattta
    24661 ttttttattc tttttttgtt gacaagaaca ttcgcaaaag gttatgattt taaatgtttc
    24721 cagataaaaa acaaaagagg aggatagtta taccttttag gatagcgcca ggtctgtgta
    24781 aacagatgac gaggagaggg tttatcgaaa gattcggcgg atggccctag ggactgcact
    24841 ctacagaaaa tccacaaaaa atatctgcaa agataaaaca aaaggatttt cctgcagctg
    24901 gaagcattca tacgaattca ttatagaaag taggatgttt tttatgtgcg gaattgttgg
    24961 aatgattgga ttaaaaaatg taacaccagg attgattgac ggtctagaaa aattagaata
    25021 ccgtggttat gattcagctg gtatctttgt ctcagatggc acaactgatt atctggtcaa
    25081 agcacaaggc agaattcaaa atttgaaaaa caaaataaat attgatacta caggaaatat
    25141 aggtattggt catacacgct gggcaactca cgggcaacct tctgaagaaa acgcccatcc
    25201 acatacttcc caaagtggac gcttcgtgct cgttcacaat ggcgtaatcg aaaactttga
    25261 agaacttaaa attgcttatt tagcaaatga ccactttatt ggtgagaccg atactgagat
    25321 tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca acgcaagagg cgtttttaaa
    25381 agctttgcgg gtcatcaaag gttcttacgc tttcgctttg attgatcgga cagcacctga
    25441 tgttatttac gtcgctaaaa ataaaagtcc actattaatc ggactcggcg atggattcaa
    25501 tgtgattgcc agcgatgcaa tggctatgct tgctcatacg aaggaattcg ttgagattga
    25561 agatgaagag atggttaccg tcacatcaga aaaagttatt attcaaaatt ttgcaggtga
    25621 catcgtagaa cgttcttcat tcgaagcaca agtagattct tcagatatcg agaaaggtac
    25681 ctatcctttt tatatgctga aagaaatcga cgaacagcct attatcatgc gtcgtatcgc
    25741 tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat caaaagctgg tcgatacatt
    25801 gtctgatagc gatcgaatct atatcgttgc ttgcggaact agttaccatg cggggttagc
    25861 aggtaaacag actctggaaa aattgacaca gatccctgtt gaggttcatt tagccagtga
    25921 atttggctat aacacacctc ttctttcaaa aaaaccattc tttattttct tgagtcaaag
    25981 tggcgaaaca gcagatagcc gccaagttct ggtaaaaatc aaccgtctcg gctacccttc
    26041 acttacgatt acaaatgttg ctggttctac tctttcgcgg gaagcatcct ttacactgct
    26101 attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa gcttatactg cacaaatagc
    26161 tgtactaact ttattagcca aagctatcgg tgataaaaaa gaatttgaaa cttctcttgt
    26221 attcgatatc actcatgaat tgagtttagt tgctaatgcg atggaatcgg tcatcgccca
    26281 aaaagattat ttagaagagt tggcagaagt atatctcagc gatacaagaa atgcctttta
    26341 cattggacgt ggcgctgact acaacgtttc tcttgaagct gctttgaaat tgaaagaaat
    26401 cagttatatc caggcagaag gttttgccgc tggcgaattg aaacatggaa cgattgcttt
    26461 gatcgaagaa ggaacaccag tgattggaat catcagtgaa gaagtgactg gtgcgcatac
    26521 tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa acactagtta ttgtctcaga
    26581 gggattagaa aaggaaagtg accagctggt gctaccaact gtccaccctt atctaactac
    26641 tctaaccaca gtcgtaccga ctcaattact tgcatattac gcaacgctat tacggggatt
    26701 cgacgttgac aaaccacgta atttagcgaa atcagtgaca gtagaataat aaaagaacaa
    26761 ggaccagtgt cagacatctg acactggtcc ttgttctttt attttttatg aaaatatctc
    26821 ttaatccagt ccgatttctt ctttgactac tgccgcgatt ttatcgacat agtaattaac
    26881 tttctcatca gtaggcgctt ctgccatcac tcgaagtaat ggttctgtac cggaaggacg
    26941 aactaggatt cttccttctg atcccatttc agcttctgcc tcttcaatca cttttttgat
    27001 tgccggaaca tccatcgcac cgtttttatc acttactcgg atattcacta atttttgcgg
    27061 atagattgtt acctctgctg caagctctga taatttctta cctgtctgtt tcatgatatt
    27121 cagtaactga attcctgaaa gcatcccatc tccagttgtg ttaaaatcta agaaaatcat
    27181 gtgcccagac tgctcgccgc caaagttata atcgtttttg cgcatttctt ctacaacgta
    27241 acgatcacca acttgtgtaa cgacatcttt caaaccgatt ccttccaccg ctttgtggaa
    27301 tcctaagtta ctcatgacag tcgtaacgat cgtatctttt ttcaatcgat ttttttctgc
    27361 caagtattta gcacagataa acatgatttt atcaccgtcg acaatgtttc caagttcatc
    27421 caccgcaata atacgatcgc catcgccatc gaaagctagt ccagcatctg ctcctttttc
    27481 aacgaccatc tcagctaaac gttctggatg ggtagagcct acgccatcat tgatatttaa
    27541 cccgtctgga tttgtgccca tggtataaaa atctgtttca agatcggcaa acaaacgatt
    27601 aacacttgtt gaagttgctc cgtttgctgc atcgacacaa atggtcaaac cggaaaggtc
    27661 accgttgatc gtttgtacaa ggaattgaga atatttcaat aagccttctg gaaattcttc
    27721 tacagttccc aatccttcag ctgatggacg aggcaattca tccacttcag catctaataa
    27781 tgcttcaatt tctagctctt ggtcatctac tagtttaaaa ccatctgcac cgaaaaattt
    27841 gattccatta tcttgtgctg gattatgaga agcagaaatc atgacccctg cgcttgcttt
    27901 ttgcaaacgt gtcagataag caacacctgg tgtagagatc acacctagct ggaacacttc
    27961 gatacccacc gataaaagtc ctgaaatcag cgcttcttct aacatttgac ctgagattct
    28021 tgtatcccgc cctactaaca cgcgtgggcg ttttccttct tcttcatgct ggcttaggac
    28081 ataacctccg caccgtccca gcttaaatgc aagttctggc gtaagttcct tgttggcttc
    28141 accgcgtacg ccgtctgttc caaaatattt acccatagtt gtaaaattac tcctttaact
    28201 taattttctg aggaatttgt tctgctcatt tgtgttgatt cgcttgtttc tgatgtttct
    28261 tctgtacttg tggtcgagct gcttgtccca gattccgaac tggaagaaat ggttgttgtc
    28321 gatggttccg ttcctgaatc agcagatgaa atacttctac tcgtacttgt attttcttgt
    28381 gtccgactgc tcgtcgaagc agagctactg cttgacgttt gcaacacggg tgtaatctcc
    28441 acactaactg attcgggctt gatacttaac ccctcttcta ctggtatttc aattttacga
    28501 gttgttcgat gattgatacc tgagacattg atcggtacag caatactgtc accgatcgat
    28561 gcaagcaaat cgctagagcc gcttacttct gcttccagtt ttgaaaaact gaaatcatag
    28621 ctttctaccc cggcagctgg tgttccttgc tgtatcccat aaagtcgtac cgacttgctt
    28681 ggcttgatcg aatcagctct cactgttact tgcactggat cagagacgat acttaatact
    28741 tcccctgctg cattcagcgc ctgtattggg acctcactat taatcccatc atctgtgacc
    28801 atcgaagcgt ccacatcagc tactactcgt ttgatttctg ccaatgtttt gtcacctgta
    28861 gtgatagaga cttttttagg actaacggaa gtatcatcaa gttcatatcc agatggtgtg
    28921 aacgttgaag gaatcaacgt ttccacatcg aaatctttta ttaccttttt ctcaaccgtt
    28981 actgtaatag tcgatggttc gatctttgct gtgacagcac tgctcaaatt ttgaattttt
    29041 agcggaacct catgtgttcc ttcgcccagc ttagtgatat ctgctgtgac gcggaacatc
    29101 cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt ttgcactgga aagtttgaca
    29161 gtcactgcat tttcatatcc atggatatag tagcgctttg aatcataaga aatcttgatt
    29221 ggcaccccag taactgtttg attatacgct tcatttccag aaagcgtatt tggaacggac
    29281 tggccatttg cattgaagta cagcgcaata ctgaacagca atgcaataaa actgtaaaga
    29341 atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc tcccttagtc ataccgtcta
    29401 ggaaagattg aatcacgttt ttcttgtttt ttgttttctc ttcagcaatc agttctctac
    29461 gcaaaattgc caaatattct tgctgggata agccagccat cagttcatta tctaatgtaa
    29521 tgctgacatc cccagtttct tcagagacaa cgatggtaat cgcgtcgctg acttcgctta
    29581 taccgacagc tgcccggtgt cgagtcccga attcttttgg aatcaacata ctttctgata
    29641 gaggaagata ggcgcttgct actgcgatct ttccttcttt tacaataact gcaccgtcat
    29701 gcagcggtgt attaggaata aagatattga tcagcagctc tccagtgata tctgcatcta
    29761 atgcaattcc tgtctcaata tactcatcta atccagtatg ccgttcgata gtaattagcg
    29821 caccgatttt tcgcttggac atatattgga tggctttgtc aaaagacaag atcatcttct
    29881 catcttcctg ctgttcgctt tttgattgtt tgaaaagcga actgcgtcca agatgttcca
    29941 gtcctctccg gatttccggc tgaaaaatca cgatagcagc tatcaccccg tacgtaatga
    30001 cttggttcat cagccaagac aaggtgtgca gaccaatgat ttccgctacg attcggataa
    30061 caataaaaat agctacacct ttcagaagct gaatcgcttt tgtgcctcgc agcagttgga
    30121 tcagtttgta tacaagatac cagacaacca gaatatcaag tatgttcacc aaaaaattca
    30181 gagagaacaa gtcaccggaa aacatttgct gccaatagtc caaattaaaa agttccccga
    30241 tttgaaatga cataaaaagc ctctcttctc ttttgagatt tcctctctag tatatcatat
    30301 gttttaattt tagaggctga tctgctcgta tttttcttga gaaaaacgca taattttcag
    30361 gaaaattgca agtatgcgtt ttatttttct ctgcaataaa tatttttaaa cttcagagaa
    30421 ttattcatta tattttttct gttatttttc ctttttttct tttgtagctt gttccatttt
    30481 tttacgtcgt tctgctctgg cagctcttct ttcttctgct tcaaggtccg tcgttttttc
    30541 ttttctagtc ttaacgggta catcgataga ttcctctggt tcaagtcgtt tcttgatttt
    30601 ttctaattct cccgtcagtg cagcatagtt gtaaaaacgt gttttagcgt cttggatagt
    30661 cttttcaaat aaagcttttg caagatttgg atttgcgttc tctagcgagg aaaagcgaac
    30721 ttgtttcctc atgaaatcag gcatagcaga gaaatcaggt tttttgtagt ccaaagtcat
    30781 tgggttcttg tttttttcga ccattgcagg gttatatcga tataatgacc aatagccaga
    30841 agaaacagct tcttttgctt ctttaagcga ttctttcatt ccaccaagca aaccatgtgt
    30901 gatacaaggc gtataggcaa tgattaaaga aggtccagga tacttttctg cttcttcaaa
    30961 agcctttatc gtctgcattt gattggcacc tgaagcaatt tgcgccacat aaacatttcc
    31021 atatgtcatc gccatcattc ctagatcttt ctttgaagca tactttccac tagccgaaaa
    31081 tttagcgatt gccgaagctg gtgttgcttt tgaggtttga ccgccagtat tggaatagac
    31141 ttcgttatcc aaaacaagaa tattcacgtc tgctccgctg gcaagtacat gatcgatccc
    31201 gccaaaacca atgtcgtaag cccatccgtc tccaccaatc atccattggc tgttttttac
    31261 gaatagatcc tttctcttgt atatatcctc cagttcaggg acaattgatc gttcgctttc
    31321 gatcgcagct tgcagttttg ctgctctttg ctgcgttcct tcgctctcaa acatgtgtac
    31381 caaccagtct tccatcaatt ctcgtagttc ttctgatact tttggcaata cttctttgat
    31441 tgaacttgcc aaagcctcgc gacgagtctg tgccgctaga agcataccat aaccaaattc
    31501 agcattatct tccaataaag aatttgacca tgcaggccct tgaccacatt cattggtcgt
    31561 ataaggagaa gcaggagaag caccgcccca aatagaagaa cagcctgtcg cattcgcgat
    31621 catcattcga tcaccgaaca tttgtgtcaa taattttaca taaggtgttt cgccacagcc
    31681 tgagcaagcg cccgagaatt caagaagcgg ttgattgaat tgtgtagaca agacagtatt
    31741 ctttcctttg actggatttg ctttttgtct taatgtcatt gcaaaagccc aattcacagc
    31801 ttgttctttc tgttcttcat aaggcttcat cactaaagct ttttcttttg cgggacaagc
    31861 ctctacacac agaccacaac ctgtacagtc ttccactgaa acttggatac ggtattttac
    31921 gccgtctgcg cctcgcattt ctctcacgat aaatccttct ggcgcttctt ccatttcctc
    31981 ttcatctgct aaaaatggac ggatggcagc atgaggacaa acaaaggcac attcattaca
    32041 catcgtacag cgatcactaa tccactcagg tacttctaaa gcgacgcccc gcttttccat
    32101 agaagccgtt cctaaaggca tttcgccagt tgtcattcca tttgctacaa gtgtaccaac
    32161 agagagttga tttccttcct gtgcattcac tggttcaagt atttcttgta tataaccagt
    32221 gttcctttta ttgatttttt caggcatctc caacgttctc caatggtctg ggatcgcgac
    32281 ttgatgaagc agttcggtcg tccgatcgat tgcttgtatg tttttttcta cgatagccat
    32341 tgatttatgt ccatagcttt tcagggcttc ttcttttagc agcggaagca cctcatcaaa
    32401 aggaatgatg tcagctaatt taaaaaaagc cgtttccatt gccgtattga tccggcgtcc
    32461 caaaccgact tcttgggcca atctcatggc attgatcgta tagaatctaa tgttattttc
    32521 agccaagtaa cgttttaatt ttaagggcag atgcgtttct aattgttcgt cgctccaaag
    32581 agtattcaat aaaaaaatgc cacctggctt caatcctttg accaagtcat agctatgcag
    32641 gtaagctggt gtgtgacagg caacaaggtc cgcatgctcg acaagatacg ctgaacgtat
    32701 cggcgtatct ccaaaacgaa gatgagagac agtcagaccg ccagattttt tcgaatcata
    32761 ataaaaatag ccttgcgcat atttatcggt gtgatctcca ataatcttga tagctgattt
    32821 atttgctcca actgttccgt cagatccaaa tccccaaaac ttggcctgga atgtttgcgg
    32881 ttctgtcaaa tccagacttt cctttggttc caaagattga taagtcacat catccacgat
    32941 ccctatggta aaccgttttt tgcgtatgct tgggtctttt ttcaattcat caaaaactgc
    33001 tgagatttgg tcgggagtca catctttaga ccccaatccg tagcgaccac caataacagc
    33061 cgggcgaagt tcagaatcat ataacgcact ttgaacgtct aataagagag gttctccacc
    33121 tgcccctggt tctttacttc gatcaagaac agcaattgtt tttactgtat gaggcaactt
    33181 ttgcacgaat gtttccactg gaaaaggacg ataaagatgg atattcaaaa aacctgtttt
    33241 ccgtccgttt gcattcaagt aatcaatcgt ttgttcaatc gtctgtgcaa ctgatcccat
    33301 agaaacaatg acttcttccg catcgtctgc tccgtaataa gtcaccaagt cataagaagt
    33361 tcctcgtaat cggttgatct ctttcatata tttttgaacg atttcaggta atttatcata
    33421 ataggggttg atcgtttccc gttgttgaaa atggatgtct ggattctggt tcgtaccact
    33481 aacagtcgga tgattgggat tcatccctcg tttacgaaat gaagctaatt tctcctgatt
    33541 gatcagagga gctaattctt catattccaa aacttcgatt ttttgaatct cgtgactcgt
    33601 acggaatcca tcaaagaaat tcaaaaaagg tacttctcct tcaatagaag caagatgggc
    33661 aacaggtgct aaatccatca cttcttgtac actgctttca gctaacatag caaatcctgt
    33721 ttgtcttgca gccatcacgt ctccgtgatc tccgaaaata ttcaacgcat ttgtcgtcac
    33781 tgcccgacta gcaacatgga aaacacttgg cagtagttcc ccagcaatct tgtacatatt
    33841 cggtatcatc aaaagcagcc cttgagaagc ggtatatgta gttgtcagtg caccagtttt
    33901 caatgatcca tggaccacac cagctgctcc tgcttcggat tgcatttcta ctacttttac
    33961 tggttgaccg aatacatttt cttttcctgc tgctgaccat tgatctacta attcagccat
    34021 ggtcgaactg ggtgttattg gatatattgc agcaatctcg gtaaatgcat aagaaatata
    34081 tgcggctgcc gtattgccat ccattgtttt catttttcgc atgattcatc atccttgttc
    34141 atattctctc ttattatctg ttccattata acgtaaaaca ttccattttt tcttttattt
    34201 ataaaaatat ttcacatatg tctatttgaa ttggtcatct aatttttaga caaacagtct
    34261 aaatcgttgc ctttttttgt cagacatgta taaactataa gcgaaagagg tgttttaaca
    34321 tggatatatc agtgattgat gcaacgaaaa caaatacaca aaaaggaatc ctttatggtt
    34381 catcgaatgc tcctaaaaaa atggtcgaat tcatcaacct atcttgtccg tattgccgac
    34441 aatggtttga agaatcttat gagctattag aagaagcagt ccaaagcggg caattgcagc
    34501 gagtgatcaa attgttcgat aaagaaaaag aaagcttgca gcgaggaaac gtgatgcacc
    34561 ggtatctcac aatcagcgat ggtcaaaaag cgatcaaaga gatcaaacaa atattcgata
    34621 ctcaagacga gtggaaacat ctttctctcc aagaagtagc ggattttgca gtagataaac
    34681 taaagctgac agaacaaaaa gacgaacagc tgagccaagc tgtcatcaac gaagctgagc
    34741 aagcacatat tcgatttgtt ccgactgtca tcttgggtaa agaaatcttt gatgaatcta
    34801 tttcaataga ggaattaaaa gaattgatcc aaacaaaata aaaaaataag gagcgtagga
    34861 caaaagtaaa gaacactttt gtctcacgct ctaaacacct ataaacggcg gaagcagaag
    34921 caactccttc ttatttcttg gagttaaacg cttctgtccc agcctcctta ttccgaataa
    34981 atggtgtcca aaagcttgca tctgccagat tatctcattt cttatgacaa gctgagcaaa
    35041 ttatctccac caaataattt attcatattt ttgacttgcg catactaact aattcttaaa
    35101 ttttcataca aaatttctca aattccctta acgagtaata tttatgtacg gtgattcaca
    35161 ctagtatccc aatcactttt taagttatcc cgatttcaat tctacttcaa aaatagttgc
    35221 ttttatgtat gctgttagtt gattagatgg tcgtttgttg agctaggtcg tttattttaa
    35281 acaagttgtt tctttagctt atacctatct cgtctaccaa acgcaagatg gcaaacacaa
    35341 atgcatacgc atctgtattt gccactttga ttcgtataaa gctaacaact cctaactcct
    35401 ctcatttaat agttgctctc ttttttattc agatacattt ttgctgatca cagcctagta
    35461 tttcaatggt tttgaacact aaaccaaatt gttccattac aacattcact ggctgatgaa
    35521 atggattaat agatttcgat tattcaaagc gattttctat tggtggattg tgttcccaac
    35581 taacaagacg gattccaaag tcattatata actcttcaag agttaaccct ttcctgttcc
    35641 caatagatgt atctctccca cgctcgatat aaaatatgga gtttcgaatg ccaagacctg
    35701 gcaaatcttt ccttgttaca gttacactgc tactaacttc cccatataaa atccagctcc
    35761 tccaaaatga taatatattt ttcgaccatc atctaactca tgtaacaata attgttgtgc
    35821 cctcttgtca ctcgccaaat gcaaacgcca cgtgcgatac catgccatgc tacctgcatc
    35881 tgcagaaaat ccatcaaata atgcaacaat tgtatcttct atcacaatcc tttccccatc
    35941 tacttcatat tctaatctaa aatcaaactc ccctcgggta atcgcaggtc ttggtggctt
    36001 aggacccaat attattctac ttaaaaccgc attcgttccc agatgaaaca cagctataac
    36061 aacaataatg attaatattt tgtttctatt tgataaattt ctcattattc gcaaatcacc
    36121 tctacattct cacatactag ttcgtaatac tcctttaata tcaaaatatc tactgatcgt
    36181 aataatattc gctatgaatt cctactactc gtataagaaa ggccaaatca tcagctttta
    36241 cttgctgatg atttggcttg tttctattta tcgtaattgt tttctaatca ccaaaattgt
    36301 taacaatcgg ttcagatatt tcccaattca ctagccttat attatattga tttaacaatt
    36361 cttcttcatt tattgtattt tgatcaagcg gaccaaattg ttctaataat tctttgtcat
    36421 gtaaaatatc ccttctagta atgcctcttt ccctttcaat gaaagaagca ctaggaaaag
    36481 tatgattata accattcaac ctatctccca tgtaataatt agcaggtcct ggaaaataaa
    36541 atatttgctt attatcacta acttctaaca gcaacactaa atcttctccg ctggctaaac
    36601 gacttgtcca tctacgatat ctccctatgc cttcgttcat tccaaatcca tcaaattcaa
    36661 ctattaacgt gtcttctatc acatgtaatt cttcattcaa ttcatactca agtctaaaag
    36721 gaaattctcc atatgtaatc tctggcaatg gtggtgctgg agttctccaa ataaatacaa
    36781 taactgtgaa tagaaaaaat ccaacgatcg atataaatgt tatgagacct gctcgaagta
    36841 aaacccgata taataaaaat gctgtatttc gctttgctat atctagaaaa ataaaaagta
    36901 ctgcaatcat aatgatagta aaagttgtaa aaaaacgcat ttttgccctc cctttataaa
    36961 catcgattct caaattctaa accaaatctt ggtagttcaa gttcaggtat aacgtattcc
    37021 aaccatacat ctcaattact atttatgaac ttatgattat cactgaataa atcactccat
    37081 ccccttgtta aaacttctac attaattaca cctggttgtt ttcgactagc taatccaatg
    37141 aacttatcaa ccatccttat ccaccaacca cgagaatctt gaccagaagt aagaagagca
    37201 gttctcaagg atgatcgagc agttccttcc agttttttaa ttaatcaggc cagttataga
    37261 taaatacttg atcttatcta tatcaggact tctatattaa gcaaaaattt atgtacaaaa
    37321 ctaaaatctt cattcagttg tctccccgct ttttatacga ttgtattaaa aacaatagaa
    37381 gcctttccaa attatgttac tccagtaaag atggaattat agtttgacgg aagaaaagca
    37441 agtataactt ttaaaaaaaa ctgatacatt cgcatctcct gcttcatgta tcagtttttt
    37501 ctttggatta aactgcttct tcacgcagtt tttccgcaaa ttcatttatt ttgcgaattc
    37561 ggtgattaat tcccgatttt gatatcgcac ctgagggaat catttcccct aattctttca
    37621 agctgacctc tggatgttga agccgaagtt ctgcgatttc ctgaagtttt tcaggaaggg
    37681 catgtagacc gacctttgct tcgatcaatt cgatgttttc gatttgttta gaagccgcat
    37741 caatcgtctt gttcagattt gctgtctcac aattgactag acgattgacc gaatttctca
    37801 tatcccgtac gattcgaaca tcttcaaatc ggagcattga gttggttgca ccaatcaatg
    37861 ttaagaaatc agcaattttt tctgctcctt ttaaataaga aatatagcca ttgcgccgtt
    37921 caagcgttcg agcatgtaga ccgtaataat ttaacatatc gcaaatgtct tggttatgct
    37981 gttcataaat agaaaatatt tccaaatgat aacggctcgt ttccggatta ttgactgaac
    38041 ctgaggccat aaaagcacca cgtaagtaag aacgcatttt ttgcgaattt cccataatct
    38101 cgtccgaaac gtgtccattg aacatcatac catccatgat atcaagatcc atcaacacat
    38161 cttttgtgcc ttgcttcaac cggacgatat agacattgtt cttttttaat ttcatttttt
    38221 tacgaacgag tagctcactt cgtacctgat aatgatcttt caaaagagaa tagatacgtc
    38281 tggcaattgc agcattttct gtttggacgt tcaaaataaa ctgctggttc acaataccta
    38341 aagagccgtt cattcgcagc aaagcagcta attccgcttt cgcatgttct cgatgaactt
    38401 ccaaaccagt tagttctttc ttcacatctg cagcaaatga catcctattc tcctcctttc
    38461 tccaacaata aattgcttaa tattttgaac cgaaaactaa acggaacaat tcttctacta
    38521 ctttgtctcc atcgtggaag acaccaccat ctttcaattc caaaaagtcg gtggaaatca
    38581 ctcgacatcc ttcatttctc aatccgttga agtcgtgtgc gacttgtact agatactcat
    38641 catagatctc tgggtccata taatcttcag gcactttttc cgtattgacc aatactgtat
    38701 cgataaaagg ctgattcaaa tgcttgtgta aaacacgtat atgatcggca tctgtgaaat
    38761 gttccgtttc ccctttttgg gtcatgatat tacagatata gacggtttca gcagttgtct
    38821 tgagcattgc ttcgccgatt tctggtatca ctaaatttgg aaggatactg gtgaataaac
    38881 ttccgggtcc caaaacgacc atgtcggcgt ccataattgc tgaaacgact tttcgagccg
    38941 ctttggcttc acttttatca tttgtgttgc agacatacac acggtcaatg gttttacggt
    39001 cgatcgcgat tttagattct cctactgcag tcgttccgtc tttaaagaca gcatgcaagg
    39061 tcaaaggagt ttctgaagaa ggataaacat gtccatctac atgcatcatt tttgctaata
    39121 attgaatcgc ctcataagtg cttccccgca tctcggaaac tgcggcaatg atcagattac
    39181 cgatcgtatg attggctaaa aactgatctt cctttttgaa acggtattgg aaaatatctt
    39241 catagaattg tggcatatcc gataacgcca ctaagacatt tctcaagtca ccaggaggag
    39301 ccatagcgat cgattctctg attgcaccgc tgcttccccc atcatctgca acagtcacta
    39361 ctgctgtgat atctgctcct tgatttcgca aacttttcag gataactggc agaccagtgc
    39421 caccgccgac cactacgatc tttggttttc ttatccggta ggttttcatt ttcacgaccg
    39481 gttcaccgtc tctttccttt tatccttgtc ccgatgtgtc acattgactt tatagttttt
    39541 ccctaaagca tttgccaaac gttcagtcaa tgccacagaa cggtgttgac cgcctgtaca
    39601 gccgattgca actgtcaagc tgctttttcc ttctttaatg tatccaggca atacagtttc
    39661 cagaagatcc aaaaatttat ggtagaatga ttgcgtttca tcaaaggaca tcacataatc
    39721 atagactggc tgatcttttc cggtcaatgg tcttagttcc gggatataat gagggttggg
    39781 caaaaaacgc acatccatca caatatccga atcgatcggc aacccgtatt taaaaccaaa
    39841 tgatacaaat tcgatccgaa atccttggtc tccctttgat ttgaatgact cattgatttt
    39901 ttcacgtaat tgtcgtggtg tcaatgtcgt cgtatcaatg atcacggaag cttgggcttt
    39961 caagtcgtct agtatcgccc gttctttacg tatcccttca gtgatcaaac cgtccatcgc
    40021 cattggatgt gctcgtcttg tttctttgta gcgagccact agttcttcgt ctgaagcatc
    40081 taaaaataag atagaagtgt cgatgaagtt cgtattttcg atttcgatca gcatgttttg
    40141 gatttcttca aagaaggaac gagaacgtaa atccactcct aaagccattt ttgtgacttt
    40201 gcctgattct ttgattaatt cccagaattt tggaatcaat cgaggcggca tattatcgat
    40261 acaaaaatag cccatatctt caaaactttg gatagctact gttttccctg caccgctcat
    40321 acctgttatg atgactaatt gcaaattatc tgtcataatt acgaactcct ctcacattgt
    40381 gcatagtaaa attatatcat tccgggcgta tcattaccag ttttcttttt cttttacaaa
    40441 aagatttgga ccaaatatct tttaggatat ttgccccaaa tccaattttt ttacttttcc
    40501 gatgctgtat ccaatgcctt gcttctttca gctagcgctc gttcaatcgt ccgatctgct
    40561 aaaatagatt gggcatcgat cactggataa tggttatctt cagcaaattc atgcatcaat
    40621 gacaattctg tgcaacctaa gataactttt tcacagttta ggcgctctac cgcttcttct
    40681 aagatttcgt aatatagctc ttgattcaaa taatccgatt ccttgatctc atgatagatc
    40741 agataattga ttttttcttg aagaacagta tcaggaatca ctgtttcgaa tccaagattt
    40801 ttgacttcgc gttcatagat tccagctttc atacttcctt ctgttcctag aatcgctact
    40861 ctccctgtcg tatgctgacg gacaagttca tttgctgctt ctcttggcat atgaaggata
    40921 ggaatatccg ttgccgcttg taattcttca aaaaagtagt gtgcggtgtt acaagtcaac
    40981 acaatgaagt tcggctgcaa taaattttgt ttctcaatat catccagcag aaacggcatt
    41041 ggattttctt ctgatcgatc taaaatataa gctgtacgat caggaactgt tgcatgattg
    41101 aataagacat aattcaaata ttcttgatct tttgtagctt tcgttcggtg gttgatcaag
    41161 cgaacaaaac tttctgtcgc catcgtgccc attccgccta aaatactgaa aaaattctcc
    41221 atgaactagc cttctttcac atgaaaatac tttttgaatc ttggaatata gttatggaac
    41281 atatatttca tcaacaacca gcgcttgatt gaccggtctt tttcataaaa cacagtagta
    41341 ccgtaacgat tttctttgat catttgctca gctagttttt tgtcttcatt ttcccgagca
    41401 tattctaaaa agattttttt gggcacaccc atccataatc ttgctttatc tgattgattc
    41461 gttccatagg tcgtttcaac aaagggtttg ttaaacactc gatcttctgt gacgaaacga
    41521 gccagattca agccgttcaa tgtcacaaag aaactgctac gaccttgtct caaattgatt
    41581 tcaaataatt tatattctcc atctctagga tcatacttca tatcgaaatt ggcaaagcct
    41641 gtatattcga ttttttccaa aaatgcctta atggtttgat agattttttc gttataatct
    41701 ggcatgatca caacgtaatt accaatcgat gctggtgtag gatcttctaa cagtggatga
    41761 ccaagacaca tcatccgaac ttgatgatct tcatctacat acgcatttag cacacgcata
    41821 ttactatcat cacccgggat aaaatcttgt acaatcattt cacttttata accggcttcg
    41881 tatatccggc ctaaaattaa atcgaactct tctctagtct ctaaaataaa agcttttttt
    41941 cttccttcaa attggacaga aagatactcc acactgtttg caggtttcaa agcaactggg
    42001 aattcaaaag gcaattcctg ttccaaatgt ccatttacta acatttcttc tctgacgatc
    42061 aatgttttag gatacggaag atcatattct tcacaaactt cataaaagct tactttattg
    42121 atcagtcttt caaataaaga ataatcaata tatggacaga taaaatattc tgacagctct
    42181 tgtttatgtt gggagatcaa ttctgcatat ccatcaccac aagcaatcaa aagatatttt
    42241 ttactcttat cagaatatct ttcttttgcc aaacgaagca tcgtctcgat aaacacaggg
    42301 tctttatcaa atcctggaat aacttctaca ttgacaattt tactgtagcg ggtaggggct
    42361 aactgatccg aagcatatgc ttggcagatt ttgccgtatg cttcattaaa agaacgtgcc
    42421 ataccataaa cgttcatgtc gcttcctaat aatataggga taaattcttc attttcaata
    42481 ctgttcatca ttatctctca cttactcata atctcttgtt tttcttttcc aactacacaa
    42541 ggaatatcat accataaaga aaaaagcaat caaaggaaac tcctccgatt gctcaattct
    42601 tttttgaacg gattgaactt ataggaagtt tttgtctata ccaatcagtg tagaaagaac
    42661 taccatgtaa tgattctaga acactgatat taataaaaca agcaaaaatt cattttttta
    42721 tgttttttta actatctcag ctatctatcc tctttatacc attatttttt tcaaatagtg
    42781 acctgtataa ctttctttta cgttaatgat ttcttctggt gttccagtcg caaggatcgt
    42841 tcctccacct tctccacctt ctggtcctaa atcaatgata taatctgctg ttttgattac
    42901 atctagattg tgttcaatca ctaaaactgt gttaccagca tctactaatc tttgtaatac
    42961 atgcaacaag cgggcgatgt catcgctatg aagtcctgtc gttggttcat ctagtatata
    43021 gaaattcttt ccattagaga ttttgtgcaa ttcactggca agtttcatcc gttgtgcctc
    43081 accaccggac aatgtcgttg ctggttgccc catcgtcaca taacctaagc caacatcaac
    43141 aatcgtttgc agtttgcgat gaatctttgg aatgtgcttg aagaattcta cagcatcttc
    43201 tactgtcatt tccaaaatat cagcaatgct ttttcctttg taatgcactt ctaatgtttc
    43261 agagttatat cgtttgccat gacatacttc acaaggaaca tagacatcag gcaaaaagtg
    43321 catttcgatc ttaataattc catccccgcg acaagcttca caacgaccgc cttttacgtt
    43381 gaaactaaaa cgccctttct tataaccccg catttttgcc tcgttcgttt gagcaaataa
    43441 cccacggata tcatcaaata cacttgtata agtcgctgga ttacttctcg gcgtccggcc
    43501 gattgggctt tgatcgatat cgatgatctt ttcgatactt tcgtagccgg aaattgtctt
    43561 gaatttacct ggcttagcag aattcttatt taatttttgc gctaacgatt tctttaagat
    43621 actattgacc aatgtactct ttccagaacc agacacacct gtgactgcta caaattctcc
    43681 taatggaaat tcaacactaa tatttttcag attgttttct gaagcaccag tgatcttgat
    43741 tgctttccca ttacctttac ggcgttcttt tggtacaggg attgattttt tccctgaaag
    43801 atatttccct gtcaaagaat tttcatcatt agctacttct tcaggagtgc ctgcagccac
    43861 gatttgtccg ccttgttctc cggccccagg tccgacgtca atcagataat ctgctgccca
    43921 catcgtatct tcatcatgtt cgactacaac gagggtgttg ccaagatcac gcattttctt
    43981 taatgagcca atcagtcgat cgttgtcgcg ttgatgcaat ccgatcgatg gttcatctaa
    44041 aatatacaaa actccagaaa gattcgatcc aatttgtgta gccaatctga ttcgctgcgc
    44101 ttctccccca gataatgttc cggaagcgcg actcaaagtt agatagtcta gtcccacatt
    44161 ttccaagaat gaaagtctgt catttacttc ttttaaaatc ggtttggcaa ttactttctc
    44221 ttgttcagat aacgttaagt ttgagaagaa atctactgct ttttgaatag acaactcatt
    44281 tgtttgcccg atattcgttc cattgatttg aacagataga gcttggggat tcaatcgata
    44341 acctttacat gtctgacaag ttaattctgt catataaaga cgcatttgct cacgcgtgaa
    44401 atcactgttc gtatcatgat aacgacgctc gatattcttc aatacccctt cgaaagtcgt
    44461 ttctacatcg cgaacgccac caaaatcatt ttcataatgg aaatggaaaa gatcatctgt
    44521 cccattcaag atgatatcct gatgctcttc cggtaattct tcgaatggtg tatctaaatc
    44581 gataccgaaa ctttcacaag cctgcgctaa catttgagga taatactgag agctgattgg
    44641 attccatgga acgatagcac cttgactaag tgtcttcgtt ctatctggaa tcactaaatc
    44701 ttgatcgact tctaatttga cacctaaacc atcacagtct ggacaagctc caaaaggcgc
    44761 attgaatgag aacagtcttg gttctagttc gccaacagta aatccgcaat aaggacaggc
    44821 atagtgttcg ctaaacaaca tttcttcttc accgatcacg tcaaccagag catagccgtc
    44881 tgccaatcgc agagccgcct ctaaagaatc aaatagacga gaacgaatcc cttctttcac
    44941 aatgatccgg tcgatgacga tcgcgatatc atgttttttg tttttctcca gctcaggcac
    45001 ttcacttaaa tcatagatct caccatcgac tcgaacgcgg acgtatccct ctttttggat
    45061 tcgttcgaat atttttttat gttgtccttt tttctttacc acgatcggtg ccaacacttg
    45121 gatctttgtg cgctcaggca aagccattac ttgatctgcc atttgatcta ctgattgact
    45181 ggtaatctcg atatgatcgt tgggacaaat cggatgtcct acacgtgcaa acaacaagcg
    45241 taaatagtca ttgatttccg tcacagtacc tactgtcgac cgaggatttt tacttgttgt
    45301 tttctgatca atagaaatcg ccggactcaa tccgtcgatg ctatctacgt ccggcttatc
    45361 catttgtcct aaaaactgac gagcataagc agaaaggctc tctacgtatc tccgctgccc
    45421 ttcagcgtac agcgtatcaa atgctaggga actttttcca gaaccggaca aacctgtaac
    45481 gaccacgaat ttatctcgtg gaatcgttac atctatattt ttcaagttat gggcacgtgc
    45541 accgtgaatc gtaattttat cgttagccat gttgtcctcc tactttgaag cttttaattc
    45601 taaaatcata tctcgcacat tagcggctgt ttcaaaatcc aatgctttcg ccgcattttt
    45661 catttctttt tctaatttca tcaataacgt atctttttct tctttcgtca tttcttcata
    45721 cgagacttgt accgcttctt ttgtatcatc ttccgattct ttcgtaatag aaatcaaatc
    45781 tcggatttct ttaatgatcg tttttggaac gatcccatgt tcttcattgt acttctgctg
    45841 aatcgtacgg cgtcttgatg tttcatccat cgctagacgc atagaatctg ttactttgtc
    45901 tgcgtacatg attactttac cttcttcatt ccgagcagct cgtccaatcg tttggactaa
    45961 ggaacgttca ctacgtaaaa agccttcttt atccgcatcc aagatagcaa caagggaaac
    46021 ttcaggtacg tctaatcctt cacgaagcaa attgattcca actaacacat caaattcacc
    46081 taatcgaaga tctcgaatga tttctgttcg ttccagcgtt ttgatatcac tatgcaaata
    46141 tttgactttg atccctaatt ctttgaaata atctgtgagg tcttctgcca tttttttcgt
    46201 caatgtcgtt acaaacaccc gctggtcttt ttcgactcgt tcatttattt cgcctactag
    46261 atcatcgatt tgtcccatga ttggacgaac ttcgatcact gggtcaagca gccctgtcgg
    46321 acggatgatt tgttggataa cggtatctgt ttgttcatgt tcatatggtc ctggcgtcgc
    46381 agagacataa atgatctgat tgacatgttt ttcaaactct tctaaccgaa gtggccgatt
    46441 gtctaaagca gatggcaaac ggaaaccgta atctactagc atctgttttc tcgctcggtc
    46501 accattatac attcctctga cttgaggcat ggttacgtgc gattcgtccg ccacgatcaa
    46561 aaaatcttca ggaaagaaat ccaatagcgt ataaggcggt tcaccttctt tacgtccgtc
    46621 catatgccga gaataatttt caattcccga cgtgtagccc atttctaaca tcatttcaat
    46681 atcgtaattg gttcgctgtt ctaaacgttg agcttccaga agtttgtttt catttcgcaa
    46741 gacagttaaa cgctgttcta attccgcttt gatattcgct acggcatgct ccatatgttc
    46801 atcattcgtc acaaagtgag tcgccgggaa gattgccacg tgttccgttt ctcctaaaac
    46861 ttcacctgtc agtgcattga cttctcggat acgttcgacc tcatctccaa aaaactccac
    46921 acgtaaggca cgttcatctc ttgaagccgg aaaaatctcc acgacatcac cgcgcactcg
    46981 aaaacgaccg cgctgaaaat ctatatcatt tctttcgaat tggatactga ctaagtcacg
    47041 aatcaactga ttgcgatcta gttctgctcc ctgtcgaatc gaaactactt gtttttggta
    47101 ctcaaaaggc gaacctaatc caaaaataca tgaaacggat gcaatgacga tcacatcatt
    47161 tctttctaat aatgaactag tagccgaatg tcgtaatttg tcgatctcat catttacact
    47221 tgaatctttt tcgatatacg tatcgcttga aggcacataa gcttcaggct gataataatc
    47281 ataataagaa acaaaatatt caacagcatt gttagggaaa aattccttga attccccgta
    47341 cagctgacca gccaatgttt tgttatgggc aataattagt gttggtttat tcactttctc
    47401 aataagattg gaaatcgtat atgttttccc tgttccagtc gcacctaata agatttgtgc
    47461 ttttttcccg ccgactacgc catccactaa ttggttaatc gcttcaggct gatcaccagc
    47521 cggttggtat ttcgagacaa gctcaaagtg tcgggaggta tctctctcaa tcattcttcg
    47581 tcctcctttt cattcattcc ttttcatttt acgaccaata aaaagaaaag gaaagcaaag
    47641 gcattcctta ctaaaaaatt ataccacacc gaacatactt tcgccacttt tttatcttat
    47701 tatgcatgtt acgttttata acataaaatg ttagaaactc gcattttttt cattttttcg
    47761 agcttacagt cttgtctgat tcagcacttt tcgcctataa taataaaata ttggaaattt
    47821 aggaggttga ttatgaaaag aaagcattta tttcactcat ttgttttctt aatgacagga
    47881 cttgtgacac ttgcgtttgg acatgttgca caagctgaca acactacaac ggcagagtca
    47941 agcacaagcg agacaatgca aaaaatagag cccaaaaaag acgtatacgt aattgccagt
    48001 gactctgctt ttgctccatt tgaatttcaa aacgcaaagg gcgagtacga aggcatcgat
    48061 gtaaaattga tggaaaacat cgccaaactg caaggattta acatccgaat ggactaccgt
    48121 ggtttctctg ctgctttgca agctttggaa tcaggacaag cagacggaat gattgccgga
    48181 atgactgtaa cagatgaacg aaagaaaagc tatgattttt ctgattctta ctttgatagc
    48241 gggatccaat tagctgtcaa aaaaggagat acttcgatca agtcttatga agatttgaaa
    48301 ggaaaaacag tcggagcaaa agttggtacc gaaagtgctg aatttttaag cgaccatgaa
    48361 tctgaatatg gctattctat caaatatttt gatgctgctg atcaattgta cgacgggtta
    48421 aaagttggcg caatcgatgc aatgatggat gattatccgg taatcggtta tgcgatcaaa
    48481 caaggacaag aattggaaac accgatcaaa aaagaatctg gcggaaaata tgcatttgcc
    48541 gttaaaaaag gacaaaatcc tgagcttctt aatatgttca atgaaggatt gaaagaatta
    48601 aaaagaacag gcgaatacga taagattatt aaagaatatg tagcggatgg ttcagaaact
    48661 tccagtgagt cttccactgc tgatgaatca acatttcttg gacttatcca aaacaactat
    48721 caagcattgt tgaaaggact ttggagaaca attctcctaa ctttgatctc ctttgctttg
    48781 gctatagtaa tcggtgtgat ttttggatta ttcagtgtag caccaatacg cgctcttcgc
    48841 acaattgcta gtatttatgt cgatatcatc cgaggaattc caatgatggt tcttgcgttc
    48901 tttattttct ttgggttgcc tggtatcgtt ggatttacga ttcctgactt ccttgctggt
    48961 gttatcacct tgactcttaa cgcaagtgct tatatcgcag agattgttcg aggcgggatc
    49021 aacgccgttc ctgtcggaca aatggaagct tccagaagtt taggtctttc ttataatcgg
    49081 acaatgcaaa aaatcatttt gccgcaagcg atacgcatca tgatcccatc attcgtcaat
    49141 cagttcgtta tctcattaaa agacacaacg atcatttccg caatcggtgt agtcgaattg
    49201 ctgcaaactg gtaagatcat tgttgcacgt acaacacaaa gtacgtatgt ttacttgatc
    49261 attgcgatca tgtacttgat tttgatcaca gcattgacaa aattagcaaa agttttagaa
    49321 aagaaggtga agtaagatgg cagaaaaaat cttagttgag catttagtca aaaaatacgg
    49381 cgataacaca gtattaaacg acatcaatgt gtccatcaac gaaggagatg tcgtctgtat
    49441 cattggccct tcaggttcag gaaaaagtac atttttgcgt tgcttgaatc gtttagaaga
    49501 accttctgac ggtgaaatta ttattgacgg cgcccacttg atggataaaa gcacagatat
    49561 caacttggtg agacaacata tcggaatggt attccagcac tttaacctat tccctcatct
    49621 ttctattttg gaaaacatca ttttagcacc gatggacctg aagaaagaat ctagagaaga
    49681 agcagagaaa aaagcaatca aattgctgca gacagttggt ctagaagata aaaaagatat
    49741 gtatcctgaa atgctttccg gtggacaaaa gcagcgtgtg gctattgctc gtgctctagc
    49801 gatgaaccct gacatcatgc tttttgatga gcctacatct gcactcgacc ccgaaatggt
    49861 cggtgatgtc ttgaacgtca tgaaaaagtt agcagaacaa ggtatgacga tggttatcgt
    49921 tacgcacgaa atgggcttcg ctaaagaagt ggccaatcgt gtcatgttca ttgacgacgg
    49981 aaacttttta gaagacggaa cgcctcaaca aatctttgaa aatccgcaaa atgaacggac
    50041 aaaagatttc ttgaataaag tattaaatat ttaataaaaa ccaaaaatgc ccggtcgctt
    50101 catgacgacc gggcattttt agtttcttgt tttttcactt aactgtacca gccgcatcgc
    50161 ttgttctcct gcacaaacaa gcaatcgctc tacctgttcc atcgcataag aaagtaccat
    50221 cggttcattg acgatatcaa gtacatagtc gataccacct tcagaaacta tgatgattat
    50281 cttattctaa agctggcttt tttgttggta caaacatgac aactacaaaa aaaccaggcg
    50341 aacgtatgat tgttcgtctg gtttttaatt attaatgact tagcgttttt actagaaata
    50401 gaaaatttgg gcaagtctac tttatatttt tactagaaaa actacttccg ctttttcccg
    50461 ccaaaagcat ctttaaactt atcgaagaaa ccgtcttctt gctgttcttc aactttgatg
    50521 ccgccagctt cagcgaatgc acgtaatgct tctctttgtt gttcatttag atttttcggt
    50581 gtgatcagtt ttactttgac atgttggtcg cctgttgcac caccacgtaa cttcggagcg
    50641 ccttttccac gtaaacggaa gttcgtacct gtctgtgttc cagcagggat cttcaatttc
    50701 acatctccat ggacagttgg tacttggact tcatccccca aagctgcttg tacaaaactt
    50761 aaaggcaatt catagtaaat ttcagaacct tcacgatcaa agatatcact ttcttctaca
    50821 cgaaaaacca catacaaatc accaaatggt ccgccgtttt ctccagcttc tccttgacca
    50881 gctaaacgca tttgttgtcc ttcttctaca ccagctggta cattcacttt aactgaatgt
    50941 gctttcttct catgtcctga gccatgacag gttggacaag gttctttgat ttctttccct
    51001 gtgccatgac aaacatcaca agtttgacgg ctcatcactc gtccaagtgg cgtttggcgt
    51061 tctacattga tcgtacctgc accatgacat ttatgacaag tagttggttg tgtgcctggt
    51121 tttgcaccgt ttccaccaca agtatgacag atttcttccc gattatactt gatttctttt
    51181 tctacaccaa aaatcgcttc ttcaaaagac aagtcgaccg tatattgcaa atcagcacct
    51241 tgacgaggcg catttggatc gactgaccga ccgcctcctc caaagaaaga gtcgaagata
    51301 tcttcaaaac caccgaagcc gccaccagag aagccgccga atccaccaaa tccgccacca
    51361 gctccaccag caccgtaatt tggatctgtg cctgcatgcc cgtattggtc gtatgcagcg
    51421 cgtttttgcg ggtcacttaa aatctcatat gcttctgata cttctttgaa tttttcttcc
    51481 gcatcaggtt ctttattgat gtcaggatgg tattttttcg aaagcttacg ataagctttc
    51541 tttatttcat cttctgatgc tccttttgag agccctaaga cttcataata atcacgtttt
    51601 gttgccatag gctttcctcc tattggttct catcattttc acgtcgcttg ttatcatatc
    51661 atattttgtt tgaaacaaaa accgatactt caaactattt ttcaaaagaa aaagccaaag
    51721 tagcaacttt ggccttctct cgaaattcag tgaactgatt atttatcgtc gccatcgact
    51781 tcttcaaaat cagcatcaac gacatcatct gctccgcctt gagctgcttc tggattttct
    51841 tgagcttgtt gttgtgcagc ttgttcgtat agtttaacag tcaagttttg aacgatttcg
    51901 ttcaatgcat cgcgtttagt tttcatttcc tcgatgttgt ttgcttcaac agcggctttt
    51961 aattcgtcac gagctgtttc tgcttttttc acttcttctt cgtccacttt gccttctaat
    52021 tctttcaatg ttttgtccac agagaatagc aatgcgtcta catcattacg taggtcaact
    52081 tcctctttac gagctttatc tgcttcagcg tttgcttctg catctttcac catacgttcg
    52141 atttcttcgt ctgttagacc tgaagaagat ttgatcgtga ttttttgttc tttttgtgta
    52201 cctagatctt tcgcagatac atttacaatc ccgtttttat caatatcgaa tgttacttcg
    52261 atttgtggaa taccacgagg agctgctgga atatctgtca attggaatct tcctagagtt
    52321 ttgttgtcag cagccattgg gcgttcacct tgtaatacat ggatgtctac tgctggttga
    52381 ttatctgccg cagttgagaa tacttgtgat ttacttgttg gaatcgttgt attgcggtca
    52441 atcaatttag tgaacactcc acccattgtt tcgataccta atgacaatgg tgtaacgtca
    52501 agtaaaacaa catctttcac atcaccagtg atcacgccac cttggatagc agcacccata
    52561 gcaactactt catcagggtt aactgatttg tttggttctt ttcctgtttc tttacgtact
    52621 gcttctacaa ctgcagggat acgagtagat ccaccgacta aaataacttc gtcgatttct
    52681 gattgtgaca gacctgcatc ttttaacgct tgacgtactg gtacttttgt acgttctact
    52741 aagtcagctg ttaattcatc aaattttgca cgtgtcaatg tcatttccaa atgcaatggt
    52801 ccagattctc ctgctgtgat aaatggcaag ctgatttgtg tgcttgatac gccagataaa
    52861 tcttttttcg ctttttcagc agcgtctttc aagcgttgta aagccatttt gtcttgagac
    52921 aagtcaatgc tgttttcttt tttgaattct gctaccatgt agtcgatgat tttgttatca
    52981 aagtcgtccc cacctagatg gttgtcgcca gctgttgaca atacatcaaa gacaccgtct
    53041 cctagttcaa ggatagatac gtcaaaagta ccgccaccaa ggtcgaatac taagattttt
    53101 tcgtcgcgat ctgttttatc taaaccatag gcaagagcag ctgcagttgg ttcattgacg
    53161 atacgttcta cttctagacc agcgatctta ccagcatctt ttgttgcttg acgttgtgca
    53221 tcattaaagt aagctggcac agtgataact gctttttcga ctttttcacc taaatagtct
    53281 tctgcgaatc ctttgatata ttgaaggatc attgctgaga tttcttgtgg tgtatatgat
    53341 ttaccttcta catctacttt gtaacctgct tcaccgatat ggcgtttgat tgatgaaatc
    53401 gtatttgggt ttgtcacagc ttgacgtttt gcaacttccc ctacttggat ttctccattt
    53461 ttgaatgata caacagaagg tgttgtacgg tttccttctg ggttagcgat gatttttgct
    53521 tcgtttcctt ccaatactgc tactgcagag ttagtcgtac ctaagtcaat accgataatt
    53581 ttactcataa ttaacgtctc cttctttaat tgaaagtgta agttttatat ccgcacaatt
    53641 attgtgcaac aatgaccata gttggtctta acacgcgatc atgtaatttg tagccttctt
    53701 gtagtacttc tacaatcgta tcggctggtg tatcttcagt cgctggaaca gtttgtactg
    53761 cttgatgaag attaggatca aaggcttctc ctttagcagg gattttttca attccttctt
    53821 cttccagtgc gttacgcaaa ctttccaaga ccatttccac gccttttttc aaacctgccc
    53881 cttgatcatc tgacacttct gtggctaatg cacgttccag gttgtcaatt gatggaagta
    53941 attttttggc taaatcttgt gaacggtatt tttgtaattg ctcacgctca ttttttcctc
    54001 gatttgccat atttgcgatt tcagcacgag cccgcaagta tttatcttcc atttcttcta
    54061 actcagcttt taatttcgct gtttcgaatt cttccgcttc agcttctgaa atacccgaat
    54121 cttctgcagc ttcgacatcg atttccggtt ctggctgagc atctgtcatt tctttatcta
    54181 gttcttcttg attttctttc acgatacagt cttcctttca ttattcagtc agctgtttga
    54241 ttgctcttac taagaaagag agaacgatca gctgcaaata gcttcgttat tcacattacg
    54301 agtttgacaa gtcaagcgag cggtagtaat cagcaagttt agctgctagt tctcttcgat
    54361 aaacatcgac tagaccgaac atccgagaat aaggcatact agtaggccct aacaaggcta
    54421 ttgtacctct tccatgacca tctatctcgt aacttgcttg aatcatactc atattctgca
    54481 ataaatcatt gcctaattca gcaccaatct tgatatgaat attgctatcc atcggagtga
    54541 tcatttgtgt aagtccgtct gagtctttca taaaagaaaa catcgatttg aactgatcaa
    54601 gatcttgacg gggctcataa tccaagagat tcatttgtcc actgacataa accttttctt
    54661 caaaaacatg accaagaacg gtgtcaaata actgagacat cccttctgtc gtctggaaat
    54721 atttatgaag aatcatcgga atctccgtac gaagtttatg gtacaccgtc atcagaggat
    54781 ctccgactag acggtcgttt acaatctgta ccattttttc tagttcctga cttcccatat
    54841 attcgggaag agtgaacact tggctttcta cattccccat atctgttacg acgatagcaa
    54901 taatctgtcg attattcaag ggtacgatac gaaagccagt cagtcggcgg tcttttattt
    54961 caggtcccaa tgaaaaagtc gtatagcttg tcagctcaga taatatctca gcagattgct
    55021 taataatctc attgatttca tgaaattctc tgcctagaga ctgacgaatc agcagcaaat
    55081 catcttctgc tacgcgagca ggttttaaca aatgatccac gtaataacga tagcctaaag
    55141 cagatggaat ccgcccagaa gaagagtgag tcttcaacag caatccttca tcttctaatg
    55201 ctttcatatc attgcgaatc gttgctgagc tggccttgac tccctcagac attaatgttt
    55261 tggaaccaac gggcacgcca ctactcgtat agtgttggat gatcagacgt aaaatgtcgt
    55321 tttgtcgctt tgttaacatc ttcctcacct ctcattagca ctcatatatt ctaagtgcta
    55381 attcacttat aaatatagca agaagccctt ctcctgtcaa gagaaagact ccatttttta
    55441 gcactctaaa cacaagagtg ctaattctaa ataattgatg taaatccagt tatatcaata
    55501 cttcaatacc tcattgtcaa actttctaaa ctttttcttt tcaagtttcg ataaaaaaca
    55561 aatattcttc aaactatttt tcaaataaaa agcgctcaaa cacattgttc cccaaaaaag
    55621 tccctcttgg tgtcaaataa acacggtctt cttcattaac aagtaaccct tcttgctcta
    55681 attcccttag cacatcaccg tacaccgatt caattgtttt ttgatagcga tcatagaaat
    55741 gttttttagt aatccctgtt ttttttctta gtcctaagaa catttcttct tctatttgat
    55801 tttttcgtgt caatttttct tcttccaata ccgggcgttc atttgctcgt aatgggcgta
    55861 aatagtgttg gattggtcct ttgttgcggt aacgaatatc tccaagataa ccgctagcac
    55921 cagctccaaa cccaaaatag tggtcattgt tccagtacat gaggttatgt tgagattcat
    55981 gtccggagag cccaaagtta cttatttcat attggtgacg tccatgcttt tccattgctt
    56041 caatcgtctc ttcaaacatt ctggtttccg tttcctgatc aggcagttcg agtcttcctt
    56101 gtcgtaccca gttcatgaac attgttttgt tttcgaggat caatgagtac aaagaatagt
    56161 gaggcagatc caaagccaaa gctttttcca aagtatcccg atatccttct agtgtttgtc
    56221 ccggtaatgc ataaatcaaa tcgatgctta cattggtaaa attttctgct tctaaaaatt
    56281 gcattgtttg atacacatct tctgcagtat gtttacgtcc aatttttttc aataagcgat
    56341 tgtcaaatgt ctgcactccc atggataaac gattgacgcc atagtttttc atcacttgaa
    56401 gtttttcacg ggtcaaatca ccaggattcg cttctacagt aaactcatta ccattttgaa
    56461 aaggcaggat ctctctagca cctgataata gtcgatcaag ttgtttagca gataaagaag
    56521 ttggtgttcc gcctcctaca taaagtgttt ccaaattcgc tgtaggatga ctttccagca
    56581 ttaatctcat ttcattcagc agcatttcca catactcatc tactggctgc ccttctaaaa
    56641 aaactttatt aaagtcacag taatagcaga tatgctcgca aaatgggata tgaatgtacg
    56701 cagaaacctt gttttctgcg ggatttattg tttctatcat tgaaattctt tctccttacg
    56761 tcgaaaagtc gtgcctgttt tcgaccttct taaaatcgcg ttcaagcacc aactcattga
    56821 aataagccgc atatttagaa tcaaggaaac ctagctctaa aaatgcttgc ttattgtcat
    56881 cggagctaca cggtgctttt acagcctctc gataaacggt aatcgcaaag ctgaccttcg
    56941 gcattaagtc aaaatctgca aaaatatgaa aagctatttt cacagattcc tccttaagtg
    57001 ctcagaccac aacgctttgc ttacaacctc tcatatacgc atactaaacg tatttggcga
    57061 acaaatccac taaaaaatcc aagaatcgac ttcttggatg atttttttac actcatgatt
    57121 cttcctaaac aattttgtcc ttattttatt cataaaaaa
//
LOCUS       DACDLM010000011        55759 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.011, whole genome shotgun sequence.
ACCESSION   DACDLM010000011 DACDLM010000000
VERSION     DACDLM010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 55759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55759
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.011"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..547
                     /locus_tag="IV356_000675"
     CDS             <1..547
                     /locus_tag="IV356_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HAP9014388.1"
                     /translation="KIYTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSI
                     CSIPYNNIEEIIEKDAISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIV
                     PQNVSKGVVFDRLESIYNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKAD
                     YVTVSNDKDGVSQAFERILTI"
     gene            828..2048
                     /locus_tag="IV356_000676"
     CDS             828..2048
                     /locus_tag="IV356_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HAP9014389.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2045..4765
                     /locus_tag="IV356_000677"
     CDS             2045..4765
                     /locus_tag="IV356_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP9014390.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            4749..5693
                     /locus_tag="IV356_000678"
     CDS             4749..5693
                     /locus_tag="IV356_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP9014391.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(5762..6772)
                     /locus_tag="IV356_000679"
     CDS             complement(5762..6772)
                     /locus_tag="IV356_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP9014392.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(6952..7296)
                     /locus_tag="IV356_000680"
     CDS             complement(6952..7296)
                     /locus_tag="IV356_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAP9014393.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7289..7723)
                     /locus_tag="IV356_000681"
     CDS             complement(7289..7723)
                     /locus_tag="IV356_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HAP9014394.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            7861..8598
                     /locus_tag="IV356_000682"
     CDS             7861..8598
                     /locus_tag="IV356_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9014395.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            8591..9802
                     /locus_tag="IV356_000683"
     CDS             8591..9802
                     /locus_tag="IV356_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9014396.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10009..10788
                     /locus_tag="IV356_000684"
     CDS             10009..10788
                     /locus_tag="IV356_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HAP9014397.1"
                     /translation="MEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAAL
                     SREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLKT
                     MLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHGD
                     VNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDEM
                     LEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            10858..11520
                     /gene="trmB"
                     /locus_tag="IV356_000685"
     CDS             10858..11520
                     /gene="trmB"
                     /locus_tag="IV356_000685"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HAP9014398.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(11618..13372)
                     /gene="ade"
                     /locus_tag="IV356_000686"
     CDS             complement(11618..13372)
                     /gene="ade"
                     /locus_tag="IV356_000686"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HAP9014399.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            13504..14433
                     /gene="cpaF"
                     /locus_tag="IV356_000687"
     CDS             13504..14433
                     /gene="cpaF"
                     /locus_tag="IV356_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component"
                     /protein_id="HAP9014400.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            14390..15439
                     /locus_tag="IV356_000688"
     CDS             14390..15439
                     /locus_tag="IV356_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HAP9014401.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            15436..15714
                     /locus_tag="IV356_000689"
     CDS             15436..15714
                     /locus_tag="IV356_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HAP9014402.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            15689..16159
                     /locus_tag="IV356_000690"
     CDS             15689..16159
                     /locus_tag="IV356_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HAP9014403.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16176..16478
                     /locus_tag="IV356_000691"
     CDS             16176..16478
                     /locus_tag="IV356_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014404.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            16495..16866
                     /locus_tag="IV356_000692"
     CDS             16495..16866
                     /locus_tag="IV356_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HAP9014405.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            16838..17197
                     /locus_tag="IV356_000693"
     CDS             16838..17197
                     /locus_tag="IV356_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014406.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17369..18376
                     /locus_tag="IV356_000694"
     CDS             17369..18376
                     /locus_tag="IV356_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP9014407.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            18401..19585
                     /locus_tag="IV356_000695"
     CDS             18401..19585
                     /locus_tag="IV356_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HAP9014408.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20022..21605)
                     /locus_tag="IV356_000696"
     CDS             complement(20022..21605)
                     /locus_tag="IV356_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP9014409.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22183..22326)
                     /locus_tag="IV356_000697"
     CDS             complement(22183..22326)
                     /locus_tag="IV356_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HAP9014410.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(22549..23028)
                     /locus_tag="IV356_000698"
     CDS             complement(22549..23028)
                     /locus_tag="IV356_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAP9014411.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23101..23385)
                     /locus_tag="IV356_000699"
     CDS             complement(23101..23385)
                     /locus_tag="IV356_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014412.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(23463..23657)
                     /gene="ssrS"
                     /locus_tag="IV356_000700"
     ncRNA           complement(23463..23657)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="IV356_000700"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(23729..25015)
                     /locus_tag="IV356_000701"
     CDS             complement(23729..25015)
                     /locus_tag="IV356_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HAP9014413.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25153..25824
                     /locus_tag="IV356_000702"
     CDS             25153..25824
                     /locus_tag="IV356_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HAP9014414.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            25790..26278
                     /locus_tag="IV356_000703"
     CDS             25790..26278
                     /locus_tag="IV356_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HAP9014415.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26291..27238
                     /gene="prmA"
                     /locus_tag="IV356_000704"
     CDS             26291..27238
                     /gene="prmA"
                     /locus_tag="IV356_000704"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HAP9014416.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27239..28003
                     /locus_tag="IV356_000705"
     CDS             27239..28003
                     /locus_tag="IV356_000705"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HAP9014417.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28236..30449
                     /locus_tag="IV356_000706"
     CDS             28236..30449
                     /locus_tag="IV356_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HAP9014418.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            30460..30906
                     /locus_tag="IV356_000707"
     CDS             30460..30906
                     /locus_tag="IV356_000707"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HAP9014419.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31077..32336
                     /locus_tag="IV356_000708"
     CDS             31077..32336
                     /locus_tag="IV356_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HAP9014420.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(32425..33372)
                     /locus_tag="IV356_000709"
     CDS             complement(32425..33372)
                     /locus_tag="IV356_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAP9014421.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            33766..35058
                     /locus_tag="IV356_000710"
     CDS             33766..35058
                     /locus_tag="IV356_000710"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HAP9014422.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35073..36842
                     /gene="aspS"
                     /locus_tag="IV356_000711"
     CDS             35073..36842
                     /gene="aspS"
                     /locus_tag="IV356_000711"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HAP9014423.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            36951..37826
                     /locus_tag="IV356_000712"
     CDS             36951..37826
                     /locus_tag="IV356_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP9014424.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38092..39975
                     /locus_tag="IV356_000713"
     CDS             38092..39975
                     /locus_tag="IV356_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAP9014425.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40050..40334)
                     /locus_tag="IV356_000714"
     CDS             complement(40050..40334)
                     /locus_tag="IV356_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAP9014426.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40324..41058)
                     /locus_tag="IV356_000715"
     CDS             complement(40324..41058)
                     /locus_tag="IV356_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HAP9014427.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41187..41810
                     /locus_tag="IV356_000716"
     CDS             41187..41810
                     /locus_tag="IV356_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HAP9014428.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42002..43123
                     /locus_tag="IV356_000717"
     CDS             42002..43123
                     /locus_tag="IV356_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HAP9014429.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43130..46258
                     /locus_tag="IV356_000718"
     CDS             43130..46258
                     /locus_tag="IV356_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HAP9014430.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46277..49471
                     /locus_tag="IV356_000719"
     CDS             46277..49471
                     /locus_tag="IV356_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAP9014431.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(49617..50324)
                     /locus_tag="IV356_000720"
     CDS             complement(49617..50324)
                     /locus_tag="IV356_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAP9014432.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            51089..51487
                     /gene="spxA"
                     /locus_tag="IV356_000721"
     CDS             51089..51487
                     /gene="spxA"
                     /locus_tag="IV356_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HAP9014433.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            51819..52472
                     /locus_tag="IV356_000722"
     CDS             51819..52472
                     /locus_tag="IV356_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HAP9014434.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            52698..53696
                     /locus_tag="IV356_000723"
     CDS             52698..53696
                     /locus_tag="IV356_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HAP9014435.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            53872..55680
                     /gene="pepF"
                     /locus_tag="IV356_000724"
     CDS             53872..55680
                     /gene="pepF"
                     /locus_tag="IV356_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HAP9014436.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
BASE COUNT        18324 a         9658 c        11582 g        16195 t
ORIGIN      
        1 caaaatatat acaaatctcg gaagttatga atctcagaat tataaaaata aaatgaaaaa
       61 aatttttcac gaggtaggga gtgaattttc tatcaaagag ctaaactatg agcttgagta
      121 tgaaaaatct atttgttcaa tcccttataa taatattgag gaaattatag aaaaggatgc
      181 tatcagcatt tacaaatttt ttatttttat tcctaatcgt caattgaaag ctaatatatt
      241 taaccatttg aaaaagatgc taaatgtgtc tgttactgaa tcggcacctg taaatattga
      301 aatcgtacct caaaatgtat ctaaaggtgt ggtgtttgat cgtttggaat caatctacaa
      361 tttaaagaaa cctttgagaa tcgcgatcgg agatagttta aatgacttat ctatgtttga
      421 aagtgcagat attagttttg caatgggaaa tagtcatcaa gaaatcatga aaaaagctga
      481 ttatgtcact gtttcaaatg ataaagacgg agtatctcaa gcatttgaaa gaattcttac
      541 catataaact aattaaggta gtatagaaca tagaattcta aatacggaaa aatggagcat
      601 aaattccagt acaaatagta cttcttcagt gtcaaacgaa gcgaatataa catagatatt
      661 taggattgtg acaaaaatca tgtcacaatc tttttttcga ataaacttat tttttgaagt
      721 cggccattta tcgtaatttc tttgcataat acgaacaaat tttcggttat tgatgaaaaa
      781 aaacattgaa aatggtatga taaaagaaaa aaaggaggaa atttttaatg gtgaaattta
      841 tccatgcggc agatttacat atggatcggt catttgaagg actgacaact cttgataaaa
      901 ctgtacagga aaaactattg aagacgaatc tgaccgtttt atcaaatatc attgaacagg
      961 caataataaa taacgttgat tttgttttac ttgcaggaga taattttcat caaaatcgtc
     1021 cttcattaaa aatacagaaa catttttcag aacagatgaa acggttagaa aagaaccata
     1081 tacctgtatt tataatattc ggaaatcatg atttctatca aaaagagcgg tattggttct
     1141 cctttcctaa aaatgtccat ttatttacat ccgaaacggt agagacaaaa aaaataacga
     1201 taaaaagtgg agaaactgtc tctctcagtg gatttagtta tcgtcaaccg tggattcaaa
     1261 aagacaaagt gatggaattt ccttctagag aactcacaga ttaccatatt gggttgtacc
     1321 acggggaacc tggcgtctct caaaaaggaa actatgctcc tttccaaccc tcaaagatgc
     1381 aagaaaaggg atacgattat tgggctttag ggcatatcca tgtgccaacg gtcttaaatg
     1441 aaaagcaaac aattgtttat ccaggtgcgc ctcaaggtca tactaaaaag gaacaagctt
     1501 ctacatctat tctactagtt gaattaagta aaggaagttg ccaaatacat ccgattaaag
     1561 tagcagaggt ctattggaag acaaaggaaa tatcattgag gaaagcaaga acgacaaaag
     1621 aggtcattgt tcacattcgt cagcagcttt caaaagtaga ggatggattt agtttaattg
     1681 agataaaatt aaaagattat gaccatctca atacagatgt tttggaacgg atacaatcag
     1741 gagagctatt agactatttg ttagaggaat tctcagatag gataaatgat ttctttattt
     1801 ggcgtatttc tctcatagag aatacttttt atacgaagac cccacttgct gcttctgcta
     1861 aattgatgga acagttattt caatactatc agacacctca agatttccaa caaattttaa
     1921 atgaagtata tagtcatcaa gaagcggcta gaatattgag cgaactgccg gaatatcaag
     1981 aagaaacact tgaaaaagcc aagcagctgc ttaatcaaga ttttttattt gaggaggatc
     2041 aggaatgaag attttaagga tcgagattgc tgcttttgga aaatggcgtc aaaaaagttt
     2101 tgacttttat tcaggcaatc agctgatcta tgggggaaac gaagcaggaa aatcaacgat
     2161 ttatcaattt attcaagcaa tattatttgg tttcccttca aaaggccgta aaaaaaagga
     2221 ttatacacca aaagacggct cagcctatgg cggcaaaata tggcttaaac atcctgtata
     2281 tggtgaattt gctgtcgagc gctacaagca gcaaaatcgc ggaaaatcga aggtgtggct
     2341 gggggatcaa gtgggaagtg atgagttact agaaaaactg atcgcacctt tgacgaaaga
     2401 gttattccag caggtattta ctttccagca agagcagttg atggaactag atcatttgag
     2461 agaaaaagag ctacatgatg cgctgatttc tttaggcatc acgggcagtt ctcaagtatt
     2521 ccaaaagcgg caagaatatt atcagaaagc acaacaatta ttcaagaaaa aaggccaaaa
     2581 attactaatc aatcaaaaat taaatgaatg gaaagagctg caagaaaaaa ttcatcaaaa
     2641 acaagaacag gaagcttatt ttggcaagtt gatccaacaa gaacaggaat acgagtcgca
     2701 acagcagcag ttattggcac aattaaaaga ggcgaacaaa caattttcat tagccagaca
     2761 gcaagaactt aatttttctt tatatgaaga atggcaatct ctcaaaaaaa acagcactac
     2821 aggtcttcct gatgagcaac ttcttttaga tctggagtct ttctccaaac ggtatcagca
     2881 aacaaatgag cgtttggaag aattagaagc aacactggaa aagcatagcg ggatggatca
     2941 gcagtcagcc agatattatt tttatttaga gcaggagcag gaactaaaag atctccagca
     3001 acttcaattt acagcggaac aattaaacga agaatggcaa agattacaaa ttgagactag
     3061 agaaacaaat tcagaattga agattttgga acaaaggtgg cattggcaga aaaatccgtt
     3121 accggaagaa tttttatatg aagaagaatg gaagcatctt ctggctgaag aaagaaggat
     3181 tgctgatcta gaaagccaga tttctgtgcg tctccaaata gctaaagaac agcaagagat
     3241 gattgaagca gaagtgaatg acttggaaga gacctatcca gcattattac aaaatcagtc
     3301 agagatagca ccagtctctt catctaaacc gtatatgctg atggctggcg gagcaataat
     3361 cattgcaggt atatttgtac caatgccctt gaaagtgatc cttttactaa ttggtgcagg
     3421 catgattggc tatttcttct acaaaaggca accaaaaatt aaaactaaaa atgatttctc
     3481 tgagataaaa ggaatgtggc aagaaaaact aggacaactt gatctagcct tagctcaatt
     3541 agctgaagca gaagaaaaac aaaagagaac tggagaagaa aaacagattc ttcagcaaga
     3601 agtatatcgt tttgcggatc atcggcactt aggaaagatg gatacgctca aactcatgaa
     3661 agaatatgga caggaagtca tagattatca gaaattatat ggcgtatttg agcggaaaca
     3721 taaaagagaa caggaaatac aagaaaaact acgacaaatc gaccaaaaat ttgagtttgt
     3781 taaagaatgg ttaccgatac aagataagac aatttcagaa aaaatggtat tgctttcccg
     3841 ttttatacaa gagatggaac agatgaaatt tgccagaagc tatcagcaaa atactttatt
     3901 gaagcaagaa atcaatcaat tgaaaaagaa acaaaaagta tggatacaag aatacagcga
     3961 acaattgact caagcaggct tatcttatcc ttcggaagta cctgtctttt tacaaaaagc
     4021 caaacaagcc gaacagcaga tgaaaagata caatgaatta tcggaaatgc ttactccact
     4081 atttcctgaa gagctgacaa aagagaaatt atctgtaaga ctgcgccaac tgaaagaaaa
     4141 gcaatcccaa ctccagcaag aagaaaaaga agcaagtgaa aatcggcaac gactccaact
     4201 tcaagtagaa gagttgcaaa gagacggcac attggacgaa ctttatcaac aagctagccg
     4261 gcaaaaagca aaattacagg aattactgga ggaatgggga gcacttgaaa tcgccgggac
     4321 attcttaggt gatctttcaa cagagatgag tgaaagacaa ttaccccagt tgttaagagc
     4381 agcaggtgat tatttaggta ttttaacaaa aggaaattat cagaagatat tactgaaaaa
     4441 tgatacactg actttaacag acggatatac agaatttccc atctatgagt tatctacagg
     4501 tacgaaagat cagctgatta tggcgatgag atttgcttac ctctcattag aagctaaccg
     4561 ttcgatatgc ccgatcatca ttgatgatgg ctggcttcat tatgatcatc agcgaaagta
     4621 tcaattagct gaacttttag ctaaatttgg agaaaagtat caaataattt gtttttcttc
     4681 tgataaagaa atggtaagct attaccatga gatgaaccaa atcgtaaaac aattagaagg
     4741 agcaaataat gaaaaaaatt cgtgatttag taatcgatga gcagtttgaa caatttgtcc
     4801 tgatcaaaag tgcagatgta agaatcgcta aaaacggaaa aaaatttatt gcttttactt
     4861 tccaagatac ttcaggtact atcgatggta aatactggga tgcttcggag gaggaaatca
     4921 ataaatttac agccggcaca gtcgtttttc taaacggtaa aagagaggtt tatcaaggaa
     4981 accctcaagt aaagattctt catatgcgct taacaagggt agatgagcca ggagagccta
     5041 gtttatacat ggaaagagcc cctttgaaga aagaagaaat ggaagaagaa atcaatcaat
     5101 tgttgtttga gatcaccaat gcgcattgga atcgtattgt tcgctatcta cttaataaat
     5161 atcaaaaaca attttttgag tttccggcag caaaaagaaa ccatcatgca tttgccagtg
     5221 gattagctta tcatactttg acaatgcttc acttagggaa atcaatcgcc gatgaatatc
     5281 ctgagctgaa tcgagcattg ttgtatgctg gtatcatttt gcatgattta ggaaaggtga
     5341 ttgaactttc cggtcctatg tcgacagaat atacgcttgc aggaaatttg atcggtcatc
     5401 tggtattgat tgacgaagaa ataactaaag cctgtcttgc gttgaaaatc agcgaagctg
     5461 acgaagatgt tctcgtatta cgtcatatgg ttttagcaca ccatggctta ttagaatatg
     5521 gctcacctgt acgtccaaga ataatggaag cagaaatatt acatcaaatc gacaatatcg
     5581 atgcttcgat gcagatgatg ttgacttcga ttcgtcaaac agaaccagga aaatacaccg
     5641 atcggatttt cggtatggac aaccgaagtt tctatgtacc aaaagattta tagcaaaaat
     5701 ttattttttt cattcaaaac aaaaaaagcg agacataagt cttcgctttt tttgttttct
     5761 tttattttga tgaatcagtt gtttcttcag ttgaagattc ttttgttgaa tcagttgatt
     5821 ttgtgtcaga actctttgtt gaagctgtag tttcacttga gtctttcgta cttgatgaag
     5881 ttgttgtgaa tgcactcaac acattttcaa aggcatcatc tttgattttt acatttgcat
     5941 cttttaattc ttcaccgatt actttagttg tgaatgcatt gtcacttagt ttagtttcag
     6001 tagcgatatc ttttagttga tctttgtatt tatccatgtc attgccttta ttttggtttt
     6061 tcaccatttt gacaacgtag tattctgtcg cataagaagt aggatttgtt gtagtaataa
     6121 catcggagat ctcaccgtct ttcaatttga aagctgcttc ttttacttct gcaggaatag
     6181 ttgttgtcgt tgagtcgaat ttaactttac cgccatcttc ttttgtctct gtatcagttg
     6241 atttgtcttt ggctaattta gagaaatcat ctccatcatc cgctgatttt ttcacatctt
     6301 ttgcttcatc ttcacttgat aatttgatga tttgtgcttc tacttctgga tggaaagatt
     6361 tccaagcagt tttcaaatcg tcatctgtaa tatctacgtg agctttcaag ccagcttcaa
     6421 aagctaaatt gttacgaata tattctttat aagtatcttt cgtatatcca gcagcttcta
     6481 attgtgattc aaaagtatca cctaatgatt tcgcttgttt gtcgtattct gcatccactt
     6541 gcttatcggt tactttatcg ccatatttgt tattgaatac tttataaatg atcatccgtt
     6601 gtactaagga ttggttcgat gattcaagtt ttgcttcatc atagaaatca gatacagtga
     6661 tcgttccgcc tttcatcgtt gcgatatctt tattagtatc gcctgaacaa gctgctagag
     6721 ttaaaacagc caacgcacta gtagctgcca aaataattga tttttttttc attaaaattt
     6781 gcactcctgt aattagttat tatttttata tattaactat accatatccc atttccttta
     6841 aaaacgttgt cgtggtagtt tcaaacaaaa ttcaaaattt catcacattc ctaggaaata
     6901 cgcaaacttt tctcacttat atagttaaat ctgttgagaa aataatcatt attatatttg
     6961 ttcaggatac tctggcagat cagcttttag tttttctact tgttcattga tttgtgtgat
     7021 acgtggttcg gcttggaatt taaaatcttc gatatctttt ttgattgctt cttggaaagc
     7081 aggaatcaca gattcagctg tttcttttgt ttcgatcaat gcgcttttaa aatgattcag
     7141 gctgttattt aaatcatttg tcagagttgt tgcttcttcc aattcttcga tcagtttctt
     7201 tcttgtttca ttcccgctcc tgggcgccaa taacagacct ccgacagtgc cagcagcagc
     7261 tccaaataac agtcctttga aaaagttttt aatcatcgca ggacacctgc tttacgattg
     7321 tttcttgaat agcttttagt tcttccgatc cataactatc ttgatgattg acaaagtgaa
     7381 tagaaaaatc atcctctttg ctgtagcgag ggactaaatg gatatgtgaa tgaaaaacag
     7441 attgataggc tagttcacgg ttgttattca agatattaag acctttcatt tctggaaaag
     7501 ctttttccaa tgcttgagca atcttaggca cacgcgaaaa aacctctcct gcaagttcgg
     7561 gatcatattc aaaaatatct gctacatgac gtttaggcac aactaatgtg tgtcctttcg
     7621 ttgcttgaga gatgtctaaa aaagcataga ccttgtcgtc ttcatatatt ttatagcttg
     7681 ggatttcttg attgatgatt ttgcaaaaaa tacagttttc catataaaac atcctttcta
     7741 taaagaataa atacttcagc ttaactttac cataagttaa agctattgta aggaaaaaaa
     7801 caaaataccg tcattttctt cgtggtataa taaataaaaa taaatggcgg aggaaaaaga
     7861 atgagtttaa ttatcgatca tgtcacaggg gggtacggac atctccctgt gttaaaagat
     7921 atcagtttcg atgtacagcc tggagagata gtagggttga ttggactgaa cggagcaggg
     7981 aaaagtacga ccatcaagca cattatcggt ctgctggaag cttcaaaagg aacgatagaa
     8041 atcaatcatc tatccttaaa gaaaaatacg gaagaatatc gcaaacaaat tgggtatatt
     8101 ccagagactc cttctttata tgaagaattg acattgagag aacatatcga agtcactgcg
     8161 atggcctacg atatacctat ggatatagca atgaaaagag cagaaaagtt gttggagact
     8221 tttcggttat ctaatcgtct tgactggttc ccagctaatt tttcaaaggg aatgaaacag
     8281 aaagtgatga tcttatgcgc ctttttgatc gagccttctt tatatatcat cgacgaacca
     8341 tttttaggct tggatccact agctatcaat gcattgcttg aattgatggt agaaatgaaa
     8401 aaagaaggag ccggtatttt gatgtctacg catattttag ctactgcaga aaaatattgt
     8461 gatcgttttg tggtcttaca taacggagag atacgagcag acggttctct tgagatgttg
     8521 agaaaagaat ttcagctgcc ggattcttct ttggacgaaa tctatattgc tttaacaaag
     8581 gagcaggcac atgagtagtt tttttcaaaa acgtttagca agacatcaaa agaaaatgat
     8641 gaaatatatg cgttatgtat tgaacgatca ttttgtttta gtttgtcttt tcttgattgg
     8701 cggtgtggga ttatattatt ctaattggtt gaaaaccctg cagccaccgt ttgcaattgg
     8761 agggctcata atctctgtat tttggatgct ctgtttattc gtgggtaaga tggctacttt
     8821 tgcagaggca gcagatattg tttttttact tcctaaagaa aaagaaatgc aaacctattt
     8881 ggaacgagct tttcgctatt cttgcatttt tccgttgatc tttttgatat tggcatgcgg
     8941 attggccatg ccattagtgg tggttagtac ggagcaatcc ttttcgatgt ttttcgtcta
     9001 tctgatcata ttatggagtt tgaaattcag tcatctgcaa atcaagagag cagaattgtt
     9061 tcgactagat caacaagtta ttcgttattg gaaattaggc tggttttttt cttctctgat
     9121 ctttttgttt ctatcatttt attggctaat atgggcagga atagcaggtg cattagtaca
     9181 ggcaagtcta tattactggt ttttgtggaa gcaacaagaa aaaggattgg attgggagaa
     9241 aatggtgcat gtagaagaac ataggttgca tcagatctat caatttatca atttattcac
     9301 agatgttcct gaaattacgg caaagatcaa aagaagacgc tatttggatc ctatattgac
     9361 tcatattaaa agagaatcaa aaaacactta tctttacttg tttgcaagaa gattggcaag
     9421 aggttctgat tttagtggtc tttatttccg attagtaatt ataggtgggt tattgattgc
     9481 cggagtagtc gacttttatt ttagtctgat tatcggtttc ttatttttat atttgatcgg
     9541 tttccaactg ttacctttag cgaaccagtt ccgctatatg gttctcgttc agctttatcc
     9601 aatccataag aatcagaaga agcaggcgat tcagtatcta ctcacatggg tattaattat
     9661 cgcgtcggtt atttttggtt tgattgctgc agtcgtatta gatgggcagc agcgatgggt
     9721 tccgctagcg gcttatttga ttgttactat gctctttgtt aaactatatg taccaactcg
     9781 tttgaagaag atgtcagact gaaaacaaag ctgtgtaggg taaaaatgag aatgaaaaat
     9841 agagcgttga cagtaagaat gctgttcgtt ctattttttt tgagaaaagc tggttttttg
     9901 aatggcaatt aaatgaaaaa gaacgtatat gtgcttgacg tgtagtgttc aggcgactag
     9961 aataataagt actgcaaaac aaagagtaag aggacgggag aatgcatgat ggagtttcag
    10021 ttagaccaag agtggcggtt acgtcccatc aaaggcgaca caggaaaaac atacataggc
    10081 atgcgtgatg aggacaaagt ctttattaaa cgaaacacga ctccgatgtt ggctgctctt
    10141 tcaagggaag gaattacacc aaaacttgtt tggacaaaac gaacggggaa tggcgatact
    10201 ttgacagcac aagagtggct ggaaggtcgc ttgctgactc ctaatgagat tggtcaaaga
    10261 aacgacgtga ttgatgtttt gtaccattta catcattcaa attctcttaa aaccatgctg
    10321 acccgtatcg gtggtcgtgt catgacgccg gagaagatgc tgcaaaaata tgaaaaagaa
    10381 ttaccggaag aactccagaa aaatcaattt ctgcaaattg tccatcgttt tcttcgtgag
    10441 cagatcccgt caatagataa ggaaaactta tcagtagtac acggagatgt aaaccatcgt
    10501 aattggttag tatgtaaaaa ttatttatat ctagtcgatt gggattcaat catgtttgca
    10561 gaccctgcgg tggatattgc aacgatttta ggaaattatg tgccactgtc tagctggaat
    10621 cagtggctga tcagttatgg catacgcccg actgacgaaa tgcttgaaaa atttcattgg
    10681 tatgcggcca tgaatttgct ccaagaaatc accagatatt gcaaacgtga agatcatcga
    10741 cggatgaacg aagaaatttt acaattaaaa cgaattttca gtggctgagg tttggcccaa
    10801 actctgcgga gatttggcca gaccttttta attagaggaa aggaatggag ataaataatg
    10861 cgtgtccgaa atcgtccggg agcagcggaa atgttagcgg ctcacccgaa ttttgtaatt
    10921 agtgatccaa cattgtggaa gggaaaatgg aatgaattgt ttgaaaacga tcatccaatc
    10981 cacattgaga ttggtatggg gaaaggccag ttcatcactg gaatggcaaa agcccatcct
    11041 gaaatcaatt atattggagt agaaatgcag gtcagtgttg tttcgattgc actagacaag
    11101 ttgatcgaac aaccgcttcc taacctgaaa cttctacatg tggatggatc agcgttgaca
    11161 gagtatttcg ctgacagcga agtagatcaa atctatctga atttttccga tccatggcca
    11221 aaaaaacgtc atgaaaaacg gcgattgaca tataagactt ttcttgctgt agatgaacag
    11281 attcttcgtc caaatggaga aatccatttc aaaacagata atcaaggatt gtttgagtat
    11341 tctctggcaa gtttttctca atatggcatg atcctcaaac aggtatggtt agatttacat
    11401 caaagtcaat ttgaaggcaa tattatgacg gagtatgaag aaaaattttc ttcaaaaggt
    11461 caacgtattt atcgagtaga agctcaattt caagataaga ccaaaaagaa aagtctgtga
    11521 aactaacttt ctgctttcat aaaaacatta atatccataa ataaatccca gaaaatgaac
    11581 attacagatg taatgtattt tctgggattt atttgattta aaatgtattt atttcatcgg
    11641 tttttccaca aggtggaatc aattggaagc gagaaaatga aaataatcct ttgtcggtga
    11701 tcttcaattc gggtatgaca gataatgtta agaaagaaag tgtcaaaaaa ggatcaaagg
    11761 ttttagctgc tcctagttga tgtgctttag ttattaattc attcaactgt tcatagacga
    11821 tcgaaaaagg ttcctgtgtc atgattccgc ctataggaag agaaacacaa gctatttcct
    11881 gctgtttgtt gacaacggtc atcccgccac ctttttgaat caaaagatta gcagcataca
    11941 gcatatcctc gtcgtttgtc ccaacgacaa ctagattatg cgagtcatgg gcaatcgttg
    12001 tcgctatcgc tccttgtttc agctgaaatc ctttcactat gcctaatcca atgtttcccg
    12061 tttgatggtg acgctcgatc accgcaatct ttaattggtc tttttcgatt gaaggaatga
    12121 atcgttcgcc ttgtcggtcc actttttcta ccaaatcttt agtcactaga ctattcggga
    12181 taatttcgat cacatgggct tgtgaagaag aaagaagcag ctctaacgaa tgtggattta
    12241 atggttgagc gtttagtttt ggcagacaac acgtatatga atttgaatga tcagcaaata
    12301 aatggtcttg gagttgccca gattgaacaa ctaatgttcc cttatagaaa acttcatgaa
    12361 ttggcagctt ggtaagatcg tctgttaaga agaaatcagc ttgataccca ggggcaatcg
    12421 cacctagtgt tttcaaatca aaacattctg ctgcattcaa tgttgccatc tgaatggctt
    12481 gtaatggatc gattccaagt gcaatagctt gacggacgat atgatcgatt gatccttctt
    12541 ttactaaatc attgatcagt ttatcatcgg tgacaaagaa gcatcttctt gaattttcag
    12601 gtgtgatcgc cggtagtagc gatgccagat cttttgcaac ggtcccttct cgaaccatta
    12661 aatacatacc aagatccaaa cgttctttag cttcttttgc agttgtagct tcatgatccg
    12721 tccgaatacc tgctgcagga taaacattta actcttccat gccgatacca gctgcatgcc
    12781 cgtcaatttt tttcttatgc tggtgcatca attggatctt ttctaggatg tctgtttcat
    12841 tatttgctac tgcttgatag ttcatgactt cagctaagcc taaaacttcg ggtttttgta
    12901 aaaaaggggc taattttttt gcatttaaat ttgcaccatt ggtctcaaaa ggggttacag
    12961 gtacacaaga aggtagcata aaaaagatat tcatgagtgt ttgtcttgca tcttctatca
    13021 taaactcaag acctgtactc ccagcaatgt ttcctatttc atggggatct gtcactacag
    13081 tagtaactcc atgaagcaag gatacttttg aaaattcgct tggtgataaa agtgagcttt
    13141 cgatatgcac atggccatcg atgaatcctg gcactagata ttgcccatta gcattatgta
    13201 cgctttttcc ttcgtattca ccgattccta cgatcattcc ttcgcagatt gctacatctt
    13261 tttccatgat ttctttcgta aagacgttga cgatcttagc atgcttgatc actaggtcag
    13321 caggcttttt tttacttgct acttcgatat atttccttaa tgttgtttcc aatggagtgc
    13381 ctcccaagat aaatttttat aagtataaca taaattcggt ttttgccaat atttttttgt
    13441 aaattcattt tatttgaaac aaaaagatca aaaagacgta tgttttttgt ggaggggaga
    13501 ataatggaaa taaaacgatt atcggatcaa atgataagtg aaagttttgc caaacatgcc
    13561 caagacgtat atatattgcc agcttcagaa gtattttaca tctattttcg ctatggaaaa
    13621 aaacgaacat tctggaagaa agtctcttcg gcagatggac agcaactgat ctcaagattt
    13681 aagtatttgg gacagatgga tatcggagaa aaaagaaaag ctcagttagg tgcatttact
    13741 tattctttag aaaaacagga agttcgtctg cggttgtctt ctgtaggaga ttaccttcaa
    13801 cgagagagtt tagtgattcg gctattatac ggtacttttg aaacacccca tcgttgcttt
    13861 agttctcgag attttgcaac tattttacag aaaaccgtca gacgtggatt ataccttttc
    13921 agcggaccag tcggatcagg caagacttct ctaatgtatc ggttggcttt ggaagaaaaa
    13981 ttgcaagtga ttactatcga agatcctgta gagatagaag aaccgttttt tctgcagcta
    14041 cagatcaatc cgaaaatagc acagacttat gatacacttt tgagactcgc attacggcat
    14101 cgtccagact tgctaatcat tggcgagata agagatgaat caactgcaca tgctgcggta
    14161 agagcagcac taacagggca ccgggttttt gcaaccgtac atgcacgcaa tcttgaaggt
    14221 acattggtca gaatccatga actgacaaag aaaaaagaag agctatctga atgtttagct
    14281 ggtgtcattt atcaagaact tttggaagat gccaatcacc atccttctgt tttatggagt
    14341 tatcaattta tggaggaaga atcagtaaaa aaatcatggg aggaaagtta tgaagaagct
    14401 caggaaaata tttggcagtc agaactattc taaaggatta acaagaagcc agcaaaacca
    14461 gtttgcacaa accatgggag aactgctttt atctggtttt agtctgcaag aatcccttta
    14521 tttattactc acgatccgtt cgtttccacc tgttattttg gcaaatatcc aacatcagct
    14581 aaaggaaggg caagcgttta gtgaggtact ttcgcaaata ggatatggag cagagcaact
    14641 ggtacagatc gagttagctg aacgtcatgg gaatctgccg acaactttgt tggaaattgc
    14701 caaacagttt cggcttgttg aaggatttcg caatgatttg aaaaagctgc ttgcatatcc
    14761 gatgctattg ctcacctttt tgctaggtat cttgtttagt atgcggttgt tcgttttgcc
    14821 tcagcttatt ggttcaggaa tggtcatgca agagcattgg ggtattcagc tgatacaagt
    14881 ctttcattgg tatgttctac tattcatcct agcggttact ctattggctt tactagtaag
    14941 gtatcgtctg atgaagttgt ctcctgttga tcagagtgaa tggataagca gacaattatt
    15001 gattggaccg atatattcct tgtatcaatc ggcttatttg tcactagaga ttggaaagct
    15061 ttttcatgaa ggtttcgaat taaggcaaat catagtctgc ttaaaggaaa cgaaacaaga
    15121 aagtctgatt cagcatcttg cctctaagtt gattcaagga ttggaggcag gtatgtcatt
    15181 ggctgagcag ttccagaatt atcgttttct atcagaagaa ttcagtaaaa ttgttttaca
    15241 gggagaggca aagggaagtt taggtaaaga actgattttt tacagcgaat ggacaagaaa
    15301 acagcttttc aaacgtcttc atcactggat gcattttatt cagccaatca tttttttggg
    15361 cgtagcggct ttgattttat tagtttatgc cgctgtttta ttacctgttt acggaagcat
    15421 agaggaggtt ttgccatgaa aaagagaaaa atatcttatt atagcggttt tacattgatc
    15481 gaaatgctaa tcgtcttact gatcatcagt gtattagtgt tgttgttcgt ccctaatttg
    15541 tcgcgttata ggaatcatgt agaccaagaa agtcgtgaag cgatcatcca gttggtagac
    15601 acacaaaaag agctctatgc gcttcaaaat aatggaagag ttcctactgt ggaggaattg
    15661 ttgaatgaag gctatatcaa acgagaacat gcagaaatct atcagcggcc ttgaaggtaa
    15721 ggttttagca tcaggatata cgttgtttga atcactctta ctgattttat tacttacaac
    15781 gatcctttct tttccagttc tcgcattttc tgcatggaag aatgaattgg cagtctatca
    15841 atttttcggc caatttgaaa aacgaatcta ttctacgcaa aaaatcgcta ttgtgaatca
    15901 gatccaaaca ggcttttatt ggaatagtga agagaatcaa atcatttttc atgttccgaa
    15961 tccagataaa ataaattggg aagtattaga tattcctgat gagattacct tgaaacgcca
    16021 tgcttctatt acttttgctg ctagaaccgg gaatgaaagt tcactaaaag cttatcaatt
    16081 ttattgggaa gaaaaagagc ggacgattac gtatcaattc cagataggga gtggtcgcta
    16141 tacaaaaaga attgaataaa acaggatttg ttttgttgga gtcccttaca gcgcttatga
    16201 tcgcttctgt ctgtgtctac ttagtgagct ttggccagct gtttttgctt caggcagaaa
    16261 agaaaagtgg ggaggaactg ctatttattc gaatgattta tgaagatatc aagacgcagc
    16321 ggatgtatca caaaagacca gagcgaaggg aagaaatgat cccatacgat atccaaattg
    16381 tcgataataa tggagtaatc gaaaaagtgt ttgtcaatat ggagaaagaa gcgatcagta
    16441 ttgaaaaaac aagtaattcc agcatttacg ctgattgaat gtctaattgg actgatgata
    16501 ttgagcagtc tattgctcac attcaatctt ttgattcagc aaaccatcca agtaagtgaa
    16561 tttttgcagc gtaaagatca aaaagagtgg ctaatatttt tagcacaatt agaagaagaa
    16621 ctcaagagca gtcacaatgt ctctgtgaaa aatcagcaac tgcactacac gatcgaggat
    16681 aaacagtata tcatcgaaag atatcaggca atgatacgta aaagaagaac ttccggcgga
    16741 catcaaccta tgttaacaag tatcactgag cttcaattat tggaaaaaga acacacaatt
    16801 tctttttatg tacactttga aaatggagaa gatggatatg ccatatggac aaaaaacgat
    16861 cagtagaaaa tgttataagg gctctatttt attttctgtc ttgcttttat ttcttttatg
    16921 tacgttttta ttgatggcag cattagaaag ctaccgtttg tcaatggatc ttaatatacg
    16981 aatcaaaaat tattatatag caaaaataat gaagcagatg gctttatcgg aacagtctac
    17041 gcttgccgaa agttcggaag gagtttttta ctacacaact ggatctgtaa catatcagtg
    17101 ggtacaacag tccctattct tagaggtgga agtctcaccg tttatctttc ggttcacaga
    17161 agaagtaaaa aatgatacag atactagtac agaatgatgg aatgttcgtg aaaacgccct
    17221 cttttctgtt ataacactgt ttttaataaa aaaatgtttg ccgtttcaca aataaaaaac
    17281 agtgaaaacg attgaaattt tgtcaattgt tcgatagaat taaacaggtg aaaaaattgt
    17341 tataatatat ctagaaatga ggtgcaccat gttaccagaa aaaatggaac aagggtttaa
    17401 tcaaaacctg gaagctattc agcttttaca gaatgcattg ggaacttcct ttttagaagc
    17461 ctatgtcgaa aatgcagaaa atttaataga tgattatcaa gtacgtgtgg tggatggagt
    17521 gccgacaaaa gagacaacgc aacggatcac agctctttat gaagagttga agaaactttc
    17581 tttcgagcca gaagaatggc gcagactgtc tcaattactt ttattgaagg gcagccagac
    17641 agaacatttg caggcgaacc atcaactcac tcctgatagt atcggttttt tatttgtttt
    17701 tcttattgaa caactataca caaataaaaa agcaccggtt aagattctgg atattgcggc
    17761 aggaatgggc aacttgttat taacagttct tttaaaccta tcgaatgcgg ggtaccaaac
    17821 agaaggaatt ggtgtggata ttgatgatac attgttggct gtcgcagctt ctacaagtga
    17881 tttgacacaa gcaaatgttc aatactttca tcaagacggg ttgcaggaat tattaataga
    17941 tcctgtcgat tttgcaatca gcgatttgcc aatcggttat tatccgaatg acgaaaaagc
    18001 aaaagagttt ttaacaagta ccgaagaagg ccatagttat gcacatcatt tattgctaga
    18061 gcaatcaatg aaatatgtga agccggatgg ttttggtttg tttttgatgc cgagtggatt
    18121 tttagaaacg gatcaaagtg aagaaatcaa aaaatggttt aaagaagaag gttatcttca
    18181 aggaatgatt caattgccag atgaattgtt ccgtaataaa caatcgcaaa aaagtatttt
    18241 gatcttacag aaaaaaggac cacaagcaca acaagtaaaa gaagtcttgc ttgtgaaact
    18301 tgcttcatta aaagaaccag agaaggtgac ggaatttttc aacgagttta aaaactggaa
    18361 atcatctgct ctgtaatcat tcaacgagaa ggagagtcat atgtctaaaa caattgcaat
    18421 caatgctggg agttcaagtt tgaaatggca attatatcaa atgccagaag aaaccgtagt
    18481 tgcgaaaggg atcgtcgaac gtatcggttt acaagattct atttttacca tcaagtacgg
    18541 cgataatcaa aaattcgaac aaatcatgga tatcgaaaac cacgaagtag cagtaaaaat
    18601 gctgttagat cagttgattg aactgcaaat tttaagctct tatgatgaaa tcaccggagt
    18661 agggcaccgt gttgttcacg gaggagaaac ttatggggat tcagtagtga tcgatgagaa
    18721 agtaatggac cgcattgctg aattagcaga atttgctcct ttgcataatc ctgcaaactt
    18781 aatggggatc aaagcgttta aaaagatttt acctgacatt ttgagtgtgg ctgtattcga
    18841 tacatctttc cactcaacaa tgccaaagca aaattattta tatagcttac cggtgtctta
    18901 ttatgaagat ttcaaagtaa gaaaatatgg cttccatggc acaagtcatc gttatgtgtc
    18961 ggaacgtgcg gcaaaattat tgaacaaacc gatcgaagaa ctaaaaatca tcacttgcca
    19021 cttaggaaat ggtgtatcga tcacagcagt cgatggaggt aaatccatgg atacttctat
    19081 gggattcaca ccattagctg gggtgacaat gggtacacgt tcaggtgata tcgatccagc
    19141 tgttctccca tatttaatgg aaaaattaga gattgatatt gatgaaatga tcaatgtttt
    19201 gaacaagaaa tctggtctgc taggcctaac aggattgtct agtgatatgc gtgatcttga
    19261 aaagaactat gaaaaagaac atattcgttt agcttatgac attttcgtgg accgcatccg
    19321 aaaatacatc ggcggttatg tgacaacgat gaatggtgtt gatgcaattg tctttactgc
    19381 tggtatcggc gagaatgacg gacatgtacg tagtgaaatc atcaaaggta tgtcttggtt
    19441 tggttgtgaa atcgatccag cgttgaatga attgcgtggt gaagaagtag atatctctac
    19501 aaaagaatca aaagtaagag tattagtgat cccaacagat gaggaactaa tgattgcccg
    19561 tgatgtggag cgtctgcgcg gctaagccaa agcattcgtt aggataaaag atgaaacgca
    19621 tgcaagaggg aattcttgca tgtgtttttt ttgcggagaa gaccgcaaaa tggtaattta
    19681 acttcaattt cccttctttt ttacaggatc ttcttaggga attttgcttg gaaaagtggt
    19741 caaaagggaa aagactggca ttttatttat tgattttcag gaaaatccca atattttatt
    19801 ttcattcatc tttataaggg acattacata tgtaaaaaga aaaaacattt ttagatcagc
    19861 ctcgtgggct gtcgacttta ttcttcgctt tatgtttagc tagaaaaccg atccgaaaca
    19921 ttcattgatc gaataataaa aacttgattt tccacctgta ctttgcctga atcgtgaaag
    19981 cacaggtatg aaaatcaagt tttttgttgc gaaaaaacgt cctagtcaat cagttggccg
    20041 agcggctggc ggctgatctg ctcctgatca ataacgagtg cttcttggaa gtgttgctgc
    20101 aaaaagtagc ggtcatggct gactgctagg agcgttcctt gatagtcttg cagcatttct
    20161 tcaatttctt ctcgagcata gctgtcgagg tgattggttg gttcatccaa aatcaggacg
    20221 ttgatttttt ctaaaaagag tttcagcaac gccaaacgga ttttttcacc accggataaa
    20281 tctttgatcc gtttacccac atcgctttga taaaagccac ttttggctaa ttgccgtcga
    20341 gcgacttctt cgtttccagt caatgtgatg gcgtaagcca gcaaacggct atcgggatcg
    20401 gcaaactgca gctgctgcgg caaataaccg atttgcaagc tactacctaa tttgatggtg
    20461 ccaccgtaag gcttttcctc accgagtaat aatttgagta aggttgattt tcctgcacca
    20521 ttgtcgccga tgatggctaa atgatctcca cgatagactg caaaactgct gtctttgaat
    20581 agtacttgat cagcgtactg ctggtgcaag ttttgaatga tgaaaacttc tttgccagat
    20641 tttccaccat tagacaagct ttgcagccga tttttcgggg gaggtggcgg tttgacgagt
    20701 gtcagtttcg ccaggcggcg ttccagttct ttggcttttt tgaagaagga ctcattgtct
    20761 ccttcatgtg cccactgacg aaaacgacga atcatgactt tcaaccgctg gacttctttt
    20821 tgctgcagtt cgtaattttt tgtcagctca gccaagcgag cttctttcaa gactcgaaaa
    20881 cggctgtagt ttccgggata ctcaatcaat gcaccttctt ccagttccca tgtttttgtg
    20941 gtgacttgat cgagaaattg ccgatcatga gaaacgacca gaaccgattt ttttgtattc
    21001 tgtaaatagt tttccaacca gcgaatactg ttaagatcta aatgattggt cggttcatcg
    21061 agtaaaagta aatcggcatc ggctgctaaa attttggcta aagcgacttt aactcgttcg
    21121 cctccgctaa gttctgttaa ccgtgcttcc tgacggtgtg gaatccctaa gccttgcaag
    21181 atcgctgcaa tccggtcttc taatacgtaa ccgcctagtt cttcaaagcg atgctgcagc
    21241 tcaccgtaac gggccagaca cttctctaag tttgtatctg gttctgtcat caatgcttcg
    21301 tagcgactca tttgctgttt gaggtcctgt atctcagcgg cagaatggag caagtagtgg
    21361 ttgacggtcg cttcggaaac tgtaagttct tgttcgaccg tcccgatctt taagcctttt
    21421 ttgcgactga taacaccgct gtcgacacct tctctgccgg tcaagatttg taaaaaggtt
    21481 gatttgccag ttccgttgat accgactaag gcaatttttt caccagcttc aatttgacag
    21541 gataaatcct caaataatgg attcccgccg attgtttttt taatagaaat tgcttgtatg
    21601 atcatgatct ctctccttga gaccactcaa aaaggccatg gttatccatg gcctgtgtta
    21661 tttaaactca gattatcatg agaaaaatac cttgagatgg ccattgattt tacgtgaatt
    21721 caactgtttt ggacaaactt gtcccgtcaa cagcaactgt aaaaccaatt gcatggctaa
    21781 atgcgatatg gtatcgttgg taattttcat tacttgttat tttagtcatg cgcatcatag
    21841 tattttccct ccttcgtgta gttgtctttt ccagtgtacc tgaaagtgtc agaaagttca
    21901 actagcgctg acatttactt aatatttatc gatgtgtaat tctgtcagag agcttttttt
    21961 atctgactga gggtaatgtc tcgtggacca catcattgta ttctgagcta aaccagcgtt
    22021 caggcgaaat catatggtgt ttgataaaaa actttgtcta catgacttcc ttttgccatt
    22081 tgcttaatac cgttgcatta aacagctctt ctctttggaa atctcaccaa catcgcgttc
    22141 aggagtatcg ttgtggttgc aatggcaagc ggtagccttt catcaattct tgaatgattt
    22201 accgaatgta gcacttgcct tctcgcggta cccgaacccg aaataaaatt ttagtttggc
    22261 gataaaatcg gtatccgcca tcgatacttc atattttttc gtatcagatt catcggaaac
    22321 ttccacattg acgaaccaat aagctttggc atgcttaggt cgttttaaac cacaccaggg
    22381 cgactaatcg ccctggtgtt cacttttttt tattttactt gaactcattg actgttttcc
    22441 ctttatttta aacattataa agaccgatga gtgcttgccg cgtcttttgt ttttatcacg
    22501 gttttttgtg caaaaaaacc tgccgatagt tggcaggtcg tctacgtgtt aagctttggt
    22561 gtggtcttta gctggcaatt ggttttctaa atcagttcgg acaacaagca catcgcaagc
    22621 tgcgtttcta ataacatatt cagaaacaga accaataaat aaacgttcta cagcattcaa
    22681 tcctgtggct cctaacataa tcaaatctac ttgattatct tctgggattt ctctggcaat
    22741 aatttgtttt ggtgagccat attctacgac agaggttaca ttattcaagc cagctttctt
    22801 cgcattgctt tcataatctg ccaatgtttg ctttgccatt tcagtagctt gttctgcaag
    22861 cattccatca aaggatgaaa cggtttggaa agaacgtgtg tcaatgacat gtgctaatag
    22921 aagttctccg ttatttcgga tagctacatt gaccgccttt ttaaaagcta attcagcttc
    22981 atcagaacca tctacggcaa ccatgatttt tttgtattgt tgtaacataa gcattcactc
    23041 ctcaagtcaa tcgtattgta ctcttttatt gtagaacact ttagggaaaa agagaattat
    23101 ttactgcttt ggttcagcaa ttttttttgc aaatcggata ctgaaggtgg cagaaacaat
    23161 aattacgatc agtaaaaaga ccaaggcaat aaagcgttga ttgaaaaaag ctgttaaaat
    23221 acccattacg cctaaaacag catatgcagc tccgtaaaat tgtaggaatc cttgattttt
    23281 atcatttttg ttgatcaata caaaaaagat atcctgttta ttaaataaat aatagctaac
    23341 gaataataat actaaagtgg cgataatcat taaaatccta atcatgaaca aatcctccaa
    23401 aataagcaac aaatagaaaa agcaatttgc caagagcaaa ttgctttatt ctttaaaaga
    23461 tggtaatctc cgttaatgcc gttgtttgtc ctgtagtatt gatcccgcga attcaagcag
    23521 gtgggtccca tggtcgtagc ttcgaactac caaatgataa ggcatgttac cagcagtgac
    23581 acaagacggg tcccaagata tcaataaaaa tgttcggtca acacacaaag aggacaattc
    23641 gaacatcaca gatttcccac ctctatagta gcatatgaat ttaaaaagag caatgagaga
    23701 gctcgcagaa acagaaccgt tttcttgtct agttttttgg aggatgcttt ttccactctt
    23761 ttatacggta atactgttga cccagagcct gttcatattt ccctgtatct tttggctgat
    23821 aatactgagc attcttcagt ttatctggta aatattgctg attgacccaa gcctgatcaa
    23881 aatgatgagg atactgataa cccacgccac ggttgagtga tttcgcacct ttgtaatggc
    23941 tatctctcaa atgatcagga acatctccag ctttgccctc tcgaatatca gcaagtgctg
    24001 catctaatgc catgtaggca gaattggatt ttggcgacaa gcaaagatcg acgacgacgt
    24061 ctgctagtgg gatacgtgcc tcaggcaatc ccaatttttc agcagctaat acagcgttca
    24121 ctgtacgagc cgcagcagca ggattaccta aacctatatc ttcataaccg ataaccatca
    24181 gacgccggca aatacttgcc agatcacctg cctcaactaa acgggcgaga taatgaagtg
    24241 cagcatccac atcacttcca cgaatcgatt tttgaaaagc cgaaataacg tcataatgag
    24301 catctccatt tttgtcatgg gtaagagctt ttctttggac acattcttca atgatcgaca
    24361 gtgtaagatg aatccttcct tctttatctg aaggagtcga tagtgtagcc agttccagcc
    24421 cattcaatgc actccgcaaa tcgccgttcg ttgcacgcga aaggtgaaga agagcatctt
    24481 cgtctaactg gattgcttgt tgtccaaggc cgcgttcttt atcccttaaa gcatgttcga
    24541 ctgccaactg gatgtcttgt tctgttaatg gtttgacttc aaagatctgt gtacggctgc
    24601 ggatcgctgg attgatggta atataaggat tctcagtagt cgctccgatc aagatgattc
    24661 ggccactttc taaatgagga agcagaaaat cctgttttgt tttatctaat cggtgtactt
    24721 catccaataa gaggatcact gtaccactca tttttgcttc ttccgctaca acttgtagat
    24781 ccttttttga atctgtagcg gcgtttagca tgcgaaatgc ataattagta gagccggcga
    24841 tcgcacttgc gatactcgtt tttccagtac caggaggtcc atatagaatc atggaagaga
    24901 gcatgcgagc atcgaccatg cggcgtatga tttttccttc cccgactaga tgctgctgac
    24961 caacgacttc atcgatcgtt cgaggtctca tgcgataagc caatggctgt tgcataggat
    25021 tttcctcctt cttgttttta cgtcccttaa ttatatcata tttagcaaga tgcctagaaa
    25081 gaacagcctt ctgttgtttt gttttcatag cttatccaac taatattgtg tatgataaag
    25141 taggtgagaa aaatgacgga taaacaaaag atagatgaat ttttttggaa taaaacgacg
    25201 ccagaagtgg cacgggattt attggggatg tatttggagc atgacacacc agaaggaaga
    25261 ttagctggat atattgtaga cgcggaagca tacctaggtc cagaagacga ggccgcccat
    25321 agctatggtt taagaagaac accgcgtgtg cgggcaatgt atgaaaaacc aggtacgatc
    25381 tacctttaca cgatgcatac tcatcggatt ttgaacatca ttactcagcc agaagggatt
    25441 cctcaaggag taatgatacg tgcaatcgaa cccgccgcaa tgattgatca aatgagtaaa
    25501 aatcgtggcg gaaaaactgg tccagatatc agcaacggtc cgggaaaatt agtggaagca
    25561 ttagcaattc ctcaagaact ttatggtcag tctatagcag atagttcgtt acgcttagtt
    25621 tttgagaaaa aaaagacacc aaaaaagatc aatgctttgc ctagaatcgg tatcccaaac
    25681 aaaggtgtat ggacagaaaa gccgttgcgt tttgttgtgt cgggaaatcc ttatatctct
    25741 ttacaaagaa aaaaccaaat cgagaaagat tggggttgga ggaaagaaaa tgaaaaagaa
    25801 ggatctatta acatatttag atgaaataat tgaaaaacaa gtgacagact atgatgtagc
    25861 tttagattgg gatacaaaaa atcatacgat cgagatcgtt gttcgcttgt ttgcagaaaa
    25921 taaagcacaa tttgagattg atgatgcaga agggatcgtt tcgcaagaac caattatcga
    25981 atttgaagac ggcgtacttc tttttaatcc tcagaaatct gtttttgatg aacgcaatta
    26041 tctagcagta atcccttatg aaggaaaaaa agggttggca aaatcagtag ctgattcttt
    26101 agtggaatat ctaaatgaag tattagctca agggcaaagc gatttgcttg attttttgga
    26161 tgaagacgat gacgaagctg tattcgagct tcactgggat aatcagcaac tagcagaatt
    26221 agtagaagta aaacagcaaa atgaagcaga tacttattta ccgtacccaa gttattaagg
    26281 agtgacagat atgaaatgga atgaagtaaa agtagaaact gaaagtgaag cagtcgaagc
    26341 agttgctaat attttgatgg aggcaggggc gagtggtgtc gcgattgaag attctttaga
    26401 tgttgaacat tttcagtcgg atcaatatgg tgagatttta gataaaaatg attttacatc
    26461 gctgaaagaa ggcgcactag tcatggctta ttttccggaa acgactttct taccggaaat
    26521 cttgcctttt atcaaagatc gtatcacaca attacctgag tttggtctag ctattggaaa
    26581 aaataaagta acagttagtg aagtagagga aagcaactgg gcaacagcct ggaagaaata
    26641 ctatcatccg gtgcgtatta cgcgaatgct gacggttgcg ccaagctggg aaaactacca
    26701 gacagaagat cctctagaaa aaattatcac actagatcct ggtatggcat ttggcacagg
    26761 cactcatccc acgacttcct tgacattgac agcactagaa acagtcttgc gtggtggtga
    26821 aacattgcta gatgtgggaa ctgggtcggg cgtgctaagt attgcagcaa aatatcttgg
    26881 tgcaaaagat gtctatgcct ttgatttaga cgaagtagcc gttcgttcgg cgaaagaaaa
    26941 tatggatatg aatgaaatag ccaaagatgt ccatgtatca gctaacgatc ttttgacagg
    27001 aatcgagatt gaaagtgatg taatcgttgc gaacatttta gcagatatca tcttattgat
    27061 gatcccagat gcttggcgtt tactgaagca aacaggcacg ctgatcgttt caggaatcat
    27121 tgaagagaag aagcaaatgg ttctggatgc catgttagaa caagggttta tcgtggatca
    27181 aattttccag caaaaagact ggtatgcaat tattttgaaa aaaccagagg tggaatagat
    27241 gcagcggtat tttttaaaag aatcatatga atcaaaagac tattttgttt tagaagggga
    27301 aaactatcac cacattgtac gggttatgag gatggaaccc gaggatgaag tttttttggc
    27361 attcaatgat caaatagcca ttgttgcaga aatcacggag attactgaag aggctgttta
    27421 tctgaaagaa attaaaaaag aagaaaatca aaaggaactg ccaagttcga ttaccatagc
    27481 gagtggctat cctaaagggg aaaagctgga ttggatcgtt cagaaatcca ctgaattagg
    27541 agcgcaagct tttcttggtt tcccggcatc agcctctgtc gttaaatggg atgcaaaaaa
    27601 acgtatgaaa cgacaacaac ggcttgaaaa gattgctcaa gaggcagcgg aacaatccca
    27661 tcggcagatc gtgccatcag tagagttatt ggaaacgaaa caagatttat ttgagcggct
    27721 agatgattat gacgtggtct tggttgctta tgaggaatca gcaaagcaag gcgaaaaatc
    27781 aaatgcagcc aaaattctta gtgaaacaaa accagatagt cgaatcttag ctgtctttgg
    27841 accagaaggt ggattatccc gcgatgaagt cgattatttt gtagaacaca aagggatact
    27901 ttgtggatta ggaccaagaa tccttcgtac agaaacagca cctctttatt tattaagtgc
    27961 tgctagctat caatgggaat taatgaatcc ttctttcagc taacgttctt cattaataaa
    28021 agagtatcga cagaaagaat tgaaaaaata gtcaacaatt tgtataatag aaacaattat
    28081 ttatacaatg gatacgaaaa atcgtttgaa aaagctttta aaaagcgaac atttccgtaa
    28141 aaaaacgtat aactgcacgg attttgggac aattatcaaa cagatatttg tcccgattcc
    28201 cgttttaccg aaaaaagaaa gggggatcga ttcctgtgac aaaagaagaa attttaacgg
    28261 gacccggtgt cataaagctc gttagtcaat acatgggtcc cgaacatgta gcatttgttg
    28321 agaaagcatg cgaatacgcg actgctgcac atgacggaca gtttagaaaa tcaggcgaac
    28381 cctacattat tcatcctatc caagtcgcag gtatattagc agatttaaaa atggatcccc
    28441 atacagtggc tacaggcttc ttacatgatg ttgttgaaga tacagaaatc actttagaag
    28501 atctgagaga agaatttggc gatgacgttg ctatgttagt ggacggcgta accaaattag
    28561 ggaaaataaa atataaatcc cacgaagagc agctagcaga aaaccaccga aagatgctgc
    28621 tagcaatggc tcaagattta cgagttatca tggtcaaatt agctgataga ctacataaca
    28681 tgcgtacgtt gaagcacctg cgagaagata agcaaagaag gatcgctcag gaaactttag
    28741 aaatctatgc gcctcttgca catcgtctag ggatcagccg gatcaaatgg gaattagaag
    28801 atacagcact tcgttatcta aatccaaaac agtattaccg tatcgtccac ttgatgcaga
    28861 cgaagagaga agaacgtgaa aaatacgtaa gtggtactgt tgaagatatt cgaatagcga
    28921 cagaagagct ggggattttt gcagaaatct atggacggcc aaaacacatt tattcaatct
    28981 atcgtaaaat gaaagatcag aaaaagcagt tcaacgaaat ttatgacttg ctagctattc
    29041 gagtgatcgt agattcaatc aaggattgtt atgctgtatt aggagcaatc cacacaaaat
    29101 ggaaaccaat gcccggcaga tttaaggatt atattgccat gccaaaagct aatatgtacc
    29161 aatctttgca tactaccgtg atcggtccgg caggaaatcc ggtagaaatt caaatccgaa
    29221 cacaggaaat gcatgaaatc gctgaattcg gggttgctgc acactgggcc tataaagaag
    29281 gaaaaaatga aaaagtagaa ccagatggta tgacgaaaca attaagctgg ttccatgaga
    29341 tactcgaact tcaagacgaa agctatgatg cttctgaatt tatggaaggc gtaaaaggag
    29401 atatctttag tgataaagtc tacgtcttca caccaaaagg agacgttact gagttaccaa
    29461 aaggatccgg accattggac tttgcataca gtatccatac agatatcggt aacaaaacca
    29521 ctggtgcaaa agtaaatggc aaaatggtgc agcttgatta caaattgaaa aacggagata
    29581 tcattgagat catgacttct ccaaattcat ttggcccaag tcgcgactgg ttgaaattag
    29641 ttgctactag caaagcaaga aataagatca aacgtttctt caaagcccaa gatcgagaag
    29701 aaaatgtgat caaaggccac gaatccgtgg tcaaatgtat tacagatcta ggatttacgc
    29761 ctaaagatat tttgacgaag aacaaactgc aagaagcact cgatcgtttt aattatcaaa
    29821 cagaagatga tctctatgca gctgtagggt atggagaagt tagccccttg acgatggcca
    29881 atcgtctgac tgaaaaagaa cgtaaagaac aaaaaatcga gcagcaaaag caagaagcag
    29941 aagaaatcat gaatcagccg aaaaaagaac ctgacaaaat gaaagtacgt catgaaggtg
    30001 gcgttgtcat tcaaggggta gaaaacttac taattcgtat cagtcgctgc tgtaatccga
    30061 ttcctggtga tgatatcgtt ggttatatca ctaaaggcag agggatatcc attcatcgtc
    30121 gagattgtcc gaatgttcag cctgacaaac caaatgtagc agaacgtttg attgaagtcg
    30181 aatgggaaga tacatcgaat acacgaaaag agtatgatgc agatttggaa atttacggct
    30241 ataatcgttc aggcttattg aatgatgtac ttcaaacagt caatgcgcta acgaaaaatc
    30301 tcaacagcgt tgaagcacgg acgaataaag ataaaatggc gacgatccat ttgacggttg
    30361 gtatccagaa tttatcccac ctaaagagta tcgtggataa aatcaaagca gtacctgatg
    30421 tctacagtgt acgccggacg aatggatagg aggacagata tgagagcagt tgttcaacgg
    30481 gtaagtaaag ctgctgtgtc agtcgatcag caagaaattg gaaaaattgg ctacggccta
    30541 cttgttttat taggcattca tgaaaccgat acgcaaaaag atgtggacta tctggtaaaa
    30601 aaaattgcac aaatgcgtat ttttgaagat gaacaaggaa aaatgaatat tagtgtagaa
    30661 gatgtgggag gacaaatttt aagtatctct caattcacac tgtttgcgga tacgaaaaaa
    30721 ggaaatcgac caagctttgt ggaagccgca cgaccagaaa cagctattcc tttatacgaa
    30781 tcattcaatg aaggaatcag aagtcgcggc atcacagtcg ctaccggaca attcggagca
    30841 gatatgtcgg tttctctcgt caatgatgga cctgtaacga tcattattga ttctaaaaac
    30901 aaataaagta atctggtttt cactagtaaa aactatgaaa cacgtcgctt aagttagact
    30961 gataaactct aacttaagtg gcttttttgt ctgcaaaaag cgcttctttt gtcagcagtc
    31021 ggaaaaaaag ttaagcttaa attatacaag ttatttttta taggaggttg ctgaagatga
    31081 aagaagtacc agtagtagat atcaaaatca cagatttaaa aaaattgtat caaaaaggat
    31141 acaacatgtt ggaggagtta cgccatgaag cggacgctcc cgtcgtcaaa gcaaagattt
    31201 tcaataaaga agctatcacg atctacggat catcagcagc aaaagtattt tatgatccaa
    31261 ggaatttcaa acgaaaaggt gctatgccaa aattagtatt gaagacactt tttggtcaag
    31321 gtggagtaca gactttggat ggagctgctc atcaccatcg gaaaaatatt tttatggatc
    31381 taatgacacc ggaaagaatg gaagattatc atcgtatctt agataagaat ctgacacaag
    31441 cacttgaagc acagcatggt caatttgaac tatttgattt aagtaagatg gttttcttta
    31501 catctatttg cgagtgggca ggtatcaatt tatcagcgat ttctaaagat gaggtcgaaa
    31561 aattagcaga atatcaaatc tctatgatca gcggaacgtt tacttctccg attgatcaca
    31621 taaaaggtgt cgaaaatcgc aaaaaatcag aaaaatgggc gcaaggcttg attgaagaag
    31681 ctcgacaaaa tcctgtggct ggaaaagaaa atgtggcatt atatgctttt gccaatgcca
    31741 cagatttaga tggtcagctt ttacctctgg aagtggcagc tgttgaatta ttgaacatca
    31801 tccgtccaac ggttgctcta actgtgtggg cggcattgat gggacatgca cttttcagta
    31861 gaccagattt gtatcagcaa ttaaaaaatg acttttcgac gttacaagat ccgtttattc
    31921 aagaaatgag acgctattat cctttcttcc caatgctacc tgcgatttcg ctgaaagaag
    31981 tagaagtaga tggttatcgt ataccagaag gcagttgggt tattttagat ttatatggaa
    32041 cagaccatga tgaacgaaca gttgaagcgc cagattcctt tatgatcaaa cggtatgtag
    32101 ggaaagcaaa agatatttcc tataaagaag aatatgagat gattgcacaa ggcgggggaa
    32161 attttcgaca aatgcatcgc tgtgcaggag aatggatcac tcttcatagt ctacgtgtgt
    32221 tttccgatca gctagtaaat aagtttgagt tctctgtacc tgaacaagat tggacgattc
    32281 cattcaatca gtttccgact tatccgaata gccgagcgct actttacaag aattagatta
    32341 gcataaactt atcgaaaaaa aggaagatca aacagtgctg atcttccttt tttcatatta
    32401 ctataaattg ataaggtcaa ttgatcaaaa tccacgaaat gcttcatcaa tggtttgata
    32461 atcttcattg gataaatgca aatctaaagc ttggacattg tcagatactt gctctggacg
    32521 cttagctcca ggtataacta cagacactcg tggattcttc atgtaccaag ctaaaacaag
    32581 ttgcgcagga gtggcttggt atcttttagc aatggggcga agtacatcga cagcggttaa
    32641 aatttctctg aaacgttctc cttggaaatc tggatttctt tttcgaggat ctccttcacc
    32701 aaattgtttt tcctcaccaa gttcatattt tcctgtcagc aaaccggaag caagaggaaa
    32761 atagggaaca aaactgattt tgtttttttc aagataaggg aataattctt tttcagcctg
    32821 ccgatggatc aaactgtatt tatcttctac tacatcgaca tatccatctg cattcgcttc
    32881 tttcaattgt tctaacgtga agtttgacac accgactgct cggatttttc ctgcttcttt
    32941 taattcgtgc aatgtagcaa ctgattcatt ttttggtgtg ctttcatccg gaaagtggat
    33001 ataaaaaatg tcgatgtaat cagtttgcag acgttttagt gcatcttcca ccgattgttt
    33061 gagaaactca ggagaattat caaatgttcg ccctttattt ggtacatgag cagcttttgt
    33121 agcgatgacg acacgtgagc gatcatattc tttttccttc agtacctcgc caatcagttc
    33181 ttcggaacgg ccgtttccgt aagcataagc ggtatcgatc aaattgatcc cgctattcaa
    33241 agctgtacga actacttgtt ttcctgtctc atcttccaaa ccgtcaaaaa gattatgtcc
    33301 tccaacggca tttgctccta atccaagctg ttctgcgtag acttgtgaat gtccgattct
    33361 tatttctgcc atagctgatt cctccttttt gtctagtcta aaacaaaata ccaaaaagct
    33421 gaactaaaac gtttttgtga ggggaaatag tcagatatct cttgactttg agactggttt
    33481 ttagtaggtt ataagtaata tcgaatgtca atgaaagagc gagtaagttt ttgaaacttt
    33541 acaagagagg atcatcgagg ctgaaaatga tctaaagttt cattagccta aagacactct
    33601 ggagatggac gagtgaaaag ccgtcccgcg tacgagcgtt attcgtaaga ggaaagagaa
    33661 atctttcaaa attaggtggt accgtgtatg aatttcattc acccttgttc atgatgaaca
    33721 agggtgattt ttttatttac atagctaaga aagggagaga aaactatgag tttccaaaga
    33781 ccaaaaggaa caaatgatat tttgccaggc gaatcagaaa aatggcagtt tgtcgaagaa
    33841 acagcacgtt tattattcag agattatcag tataatgaaa tgcgtacacc gatttttgaa
    33901 cactatgaag tgatatcccg aagtgtaggg gatacaacgg atatcgtttc aaaagagatg
    33961 tatgattttt atgacaaagg ggaacgccat gtgacgcttc gaccagaagg tacagcacca
    34021 atcgttcgtt cttttgttga gcataaattg ttcggcccag agtatgcgaa accgttcaaa
    34081 actttttata tgggaccaat gtttcgctac gaacgccctc aaaaaggacg gttacgtcaa
    34141 ttccatcaaa tcggagtaga agcatttgga tcagaaaacc ctgcaactga tgtggagagc
    34201 atggtgatgg cacttgattt cttcaaacag ttggggatca cgcaaatccg gctagtcatc
    34261 aattcattag gtgataaaga aacgcgtcaa gcctatcgtc aagcattgat cgactatctt
    34321 ttaccttttg aatcagagct gagtgaagac tctaaacgcc gccttcatga aaatccatta
    34381 cgcgtattgg acagtaaaga caaacgagat caaaaatttg tggcagaagc tccatctatc
    34441 ttagattatc taagcgagcc tgctcaaaaa cattttgata ccgttgtttc catgctggat
    34501 gcattggctg ttccttatga aatcgacagt aatatggttc gcggactaga ttattacaca
    34561 catacgattt ttgaaatcat gagtgacgca ccaaaaatgg gggcacaagc aacgatttgc
    34621 gcaggcggac gttatgacaa tctagtggaa gaactaggtg gtccttcaac acctggcttc
    34681 ggatttgcaa tgggtatcga gcgattactc ttgactatgg aggcagagga agtagttatc
    34741 cctgcattta atgagttgga tgcttacgtg gtcgcactcg gagacgaaac aaatatcgaa
    34801 gcattgaaag tggtccaagc gattcgaaac tttggttttt cagctgaccg cgacttcatg
    34861 aaccgtaaag caaaagcgca atttaagaca gcagataaag cgaatgccaa attagtattg
    34921 gtgatcggtg aagatgagct tgctagtcaa acgattaatg tcaaagcaat ggcaagccga
    34981 aaagaaaaaa gttttccatt agaagagata tatgaacatt ttgatgaagt ctatgatgaa
    35041 atgactttat tcgagtagga ggaaaaaaat aaatggcaca aagaacgatc tattgcggat
    35101 tagtttccga acaacaatta gaacaaacag ttacattaaa aggatgggta caaaaaagac
    35161 gagaccttgg gggagtaatc tttatcgacc tacgtgatcg tgaaggaatc gttcaaatcg
    35221 tctttaatcc tgaaatcaac aaagaagcat gggaaatcgc ggataaatgt cgcagtgaat
    35281 acgtgatcga agtgactggg gaagttagaa gacgcggaga aaatgcagta aatcctaaaa
    35341 tggccactgg tgaattcgaa gtgattgcaa gtgaaatcgt gattttgaat caagcaaaaa
    35401 ccccgccatt tcaaattgaa gatgatcaag caatcagtga cgaaatacgt ttgaaatatc
    35461 gttatttgga tctgcgtcgt ccaaaaatga ctaaaaacat caaattaaga aatgcgacaa
    35521 caaaagcgat tcgtcattat ttagatgata atgactttct cgatatcgaa acaccttacc
    35581 tagggaaatc tacaccagaa ggcgcaagag actacctagt tccttcacgt gtccatgctg
    35641 gacatttcta tgcgttgccg caatctcctc aattgtttaa acaattgctg atgaatgctg
    35701 gattcgaccg ttattatcaa atcgttcgtt gtttccgcga tgaagattta cgtggagacc
    35761 gtcagcctga atttacgcaa gtagatattg aaacaacgtt cttaacagca gaagaaatcc
    35821 aaacttacac agagggattg attgcgaagg taatgaaaga agttcgcggt atcgaagtca
    35881 cattgccatt tcctcgtatg acctatgatg aagcaatggc tcgctacggc agcgacaaac
    35941 cggatacacg ttttgatatg gaattgatcg atctaagcga tacagtcaaa gaagtagaat
    36001 tcaaagtctt ccaaatggct cttgaaaacg gcggtgtcgt gaaagcattg aatgctaaag
    36061 gcgctgcaga tcgctactca cgaaaagaca tggatcagtt aggtcaatat gtaggacaat
    36121 tcggagctaa ggggcttgca tggctgaaag tagaagaaga cggattgaaa ggtccaattg
    36181 ctaaattcat gggagaagca acagaagcaa tcattaaagc aacagatgca aaaccaggtg
    36241 acttgctgat gtttggcgca gataaaagtg aaatcgtcgc tgctgcatta ggtgctatcc
    36301 ggacacgttt aggaaaagaa ttaggactaa ttgatgaatc gaaattcaat ttcttatggg
    36361 taactgattg gccacaattt gaattttcag aagaagaagg tcgatatgtc tctgctcacc
    36421 atccattcac gatgccaaaa gaagaagata tcccgttatt ggctgaagac cctgcaaaag
    36481 tctatgcaga agcttatgat atcgtcttga acggttatga actaggcgga ggttctatcc
    36541 gtattcatac tcgtgagctt caagaaaaag tactagaaac tctaggcttt acaaaagaac
    36601 aaatggaaga acaatttggt ttcttgttaa cagctttaga ttacggattc cctccacatg
    36661 gcggtattgc attaggattg gaccgttttg caatgttatt agccggagaa gataatattc
    36721 gtgaagtcat tgcctttcct aaaaacggaa aagcagcaga tgtgatgagt gatgcaccaa
    36781 gtatggtttc gcctttacaa ttgttcgaat tgaatattga tgtaacgaat atagaagaat
    36841 agccgataaa aaggtaaaaa ggatttgtcg aatacgcttc ttttgacaac cttgatttaa
    36901 ttgaaaaaca ctttataatg aagccataac atataaagcg gggcttttcc atgaaaaaaa
    36961 cattcgaaaa ttgggcttat catgattaca cgaccaagct ttcggtatct atcgtttatg
    37021 cgttgatcgc atcagtcgca ttgaatttct tttatcagcc aggacatatt tattcaagtg
    37081 gtattactgg tctagctcag attttgacga ctttgtcaaa atcactgata ggattcgaag
    37141 taccggtatc aacaactttg tatttactga atataccttt gtttgtattg gcgtggttaa
    37201 aaatcgggaa gaagtttaca attttcactt ttatcacagt cactttgacc tccctttgta
    37261 tccatatttt accggaaaca gtcctatcta ccgatccaat catctgtgcg ttgtttgggg
    37321 gggctgtgat gggactaggt attgggctag cgttgagaaa cggcctatca tcgggcggtc
    37381 tagatatcgt gagtatcacg attcgtaaaa aaacaggaaa gtcgattggt tctatttcga
    37441 tctacttcaa tgcattgatc gtttttgttg ccggaattct atttggctgg caatatatgt
    37501 tttacagtac gttgtctatt ttcgtcagtg gaaaagtaac tgatgtcgtt tatactaaac
    37561 aaaagaagat gcaggtaatg atcgtaacga aacatccaga aaaagtagta aatgaaatcc
    37621 aaaactgtat gcgtagaggg atcacgatca tcaatgaagc agaaggtgct tataagcatg
    37681 ataagcagac agtattgatg acgatcgtta cacgatacga actgcctcta cttagagaag
    37741 caatgaaagc ttctgatcca caagcttttg taagtattgc agaaaacgtc cagatacttg
    37801 gtcgtttcta tgaggatggc atttagatcg agtttgacaa aaattcatga aatactgctg
    37861 tagacagacg ttcgtttgtc tgcagttttt ttctaccata gtagaatcag caaagaaaaa
    37921 ctgctttttt atttgaaatt ttcttaaagt tgaaaaaaag catgtttatt tttttaaatt
    37981 tatgggatga tagaaaaaaa tagtagagaa aggacacgat tctacttgct attttcactt
    38041 aatacccgta tattacgaat gaaaaaagtt tatgaaaagt tggaatattg aatggaaaaa
    38101 caaaaaaggt taaaaaacag ccgctacatc actgggtttg atgggctccg ttcattagct
    38161 gtggtgggtg ttatcttcta tcaccttctg ccaactagta tgaaaggcgg ctatttgggc
    38221 gttccgattt ttttcgtcgt atctggttat ttgatcacgg atctgctgcg gcaggaatgg
    38281 gaacaaaatg gaaaaatcaa tatttggcaa ttttatgtca gaagaatgaa gagactctat
    38341 ccggcacttg tttttatgct tgtgacagct tcggcttata tcactttgtt tcagcgaggg
    38401 ctgttaaaca atcttcgagg agttgtggtc agcagcttac tgtatgtcaa caactggtgg
    38461 caaatcaata acggtttatc ttatttcgat cgatttgcta atgagtcacc gtttacgcat
    38521 atctggtctt tagcagtaga aggtcaaaac tatttggttt ggccgatctt gtttgtattg
    38581 ttgatggtat ttgttcgtaa aagaaaatgg atcttttata ctgtgttagg tacatccttc
    38641 ctctccgcca tcttgatgat gatcttgtat acaccaggag gcgatccaac ccgtgtttat
    38701 tacggtaccg acactcgtct gttttctata tggttgggaa gtgcgcttgc gtttgtttgg
    38761 ccaagtacgc gtttaaagaa aaacatcccg aaacaagcga aaaatattct gaatatcgct
    38821 ggaggaatct cgcttttggc actgattctt tgcttcttct ttttagatga tcattacaat
    38881 ttcatctatt acggaggaat gctcctagtg agtctgttat gcgtagtgct agttgcagtg
    38941 acagcacacc ccggagcaag tttgaatcga tggctgacaa atccagtatt tacttggatt
    39001 ggcaaacgaa gctatggcat ttatctgtat cagtttccag ttatgatttt ttatgaagca
    39061 aaggtgactg atattgccga tcatgttttg ttgcatactt tagtggaaat cacattgatt
    39121 ctaatcatca gtgaactttc ttatcgatat gtggagcgtc cgctagcacg ttttgattat
    39181 ggtcgtacat tccaagtgat gaaaggatgg ttcagcaaac cgatcatcag taagagcaaa
    39241 ccatgggttg ttccaggcac attacttgta gcaattgcac tcgttggttt cgttacggca
    39301 ccgaaaaacg ctgtaacagc cgatcaaaaa caactgcagg caaaaatcgc tgaaagtaaa
    39361 aaattagcag aagaaaccag aaacaattca gaaaacacca ctagttcggt tgaccaagcg
    39421 atccttgata agtacgagtt gtccaaggca caagggaata aggcacaaaa attagaacta
    39481 acggcatttg gtgattcagt tatgttggat gctgcaacgg atctacaaga actttatcca
    39541 aaagtagtgg tagatggaga tgtcggacga caattatatg ccagtgtacc gtacattgaa
    39601 aaattaaagg aacaagattt gttgaaagac actgttctga tcggactagg aacgaatggc
    39661 tcattctcgg aagctcagtt tgatagtgtg atggatgcaa tcggtgatcg aaaagtatac
    39721 tgggtcaatg tccgagtacc gacgaagcgc tggcaaaatg acgtgaatgc gatgcttgaa
    39781 cagatgacga aaaaatacga caatatgacg ctgattgatt ggtacagcta cagtaatgac
    39841 catagtgact ggttttatga tgatcaagtc catccaaatc ctgaagggat gacacattac
    39901 attcacttag tcagcgaagc cttgctagga ggaagttcaa gtacgaacag cagtgagaca
    39961 aacgtgacag aatgatagct acaaaaaact tcaggcaaaa acatttgttt ttgcctgaag
    40021 tttttttata tttaccgtgt ttttaacatt catatagatt caggaagcaa aacggttgag
    40081 tgtgtctgta aataacgttc tttttgtttt cgggtgagtt ttttgaatgc agcttctgct
    40141 tttgttgctt cgcttcttga agaaaatact tctgcatgga tcatcttaac aggtcttctt
    40201 ttttgaagac gagtatattt agcaccagta ccattgttat gttcctctaa tcgtctagaa
    40261 agatcggttg tatatccacc ataaaatgtc tgatctttac agaataatac gtaaaaataa
    40321 tgttcatttg ccatagagca tctcacgaat ctctgcagtg tattctccat ccatattgta
    40381 agtgatcaat ggtggagcga ctttgaatcc gtctaatttg ccttctttga ttccttcaac
    40441 taacaaaata tttgcctctt ttccaggttt tgggtaaaca aattggatcc ttttaggtgc
    40501 aattcgatag tcttccatga cctgaatgat ttctaagaac cgatcaggac gatggaccat
    40561 agtaaagcgt ccatttgttt ttagtagctt acttgaaata tcgatcactt cttctaacgt
    40621 cgtatgaatc tcatgacggg cgattgccag gtgtttatta gggttcgttt tatttgttgg
    40681 cagccctttg aaataaggtg gattacagac gactaagtca caagaattat gtcgaacgac
    40741 agataagctg tctttcagat cgatggtgtg gacagtcatt tgttcattta aatggttaag
    40801 cgcgatacta cgtcttgcca tgtctgctag acgaggttga agttcgatag cgtcgatagc
    40861 cgcctgggtt cgtttactta aaaaaagtcc aactgcgcca tttcctgcac aaaggtcaac
    40921 aatcttccct tttttaggta cacgggaaaa gtgagcaagc agcacagcat ctaaagaaaa
    40981 agaaaacact ttggaacttt ggataatctt gatatcttct gcgtataatt ggtcgattcg
    41041 ttcgtcttcg tgaagcatgg attccctcca aaatgaaaaa aatagtcgtc tgtattatac
    41101 tatttttatt aaaaagaacc aaggtggctt gtcaaacctc tattttttat gcatactatg
    41161 accataagaa gggaaaggaa gagactatgt tttatcgatt tatgcgcggg gtagttcgag
    41221 tactattagc cttagttaat ggaaatgccc gctatgagaa taaagaagtt ttaccgcaag
    41281 atgagaatta catactagtt gctccccatc gtacttggtg ggacccatta tatctggcgg
    41341 tagctgcagc acccaaggaa ttcagcttta tggcaaaaga agaactgttc aaaaatccag
    41401 ttctgcgatt tatattaact cgatccaatg cttttccagt taaaagagaa aatccaggac
    41461 caagcgtcat taaaacacct gtaaagattt tgaaatcgac aaatttgagt ttgatcatgt
    41521 ttcccagtgg gacaagacat gctacagaac ttaaaggcgg aatggcattg atttccagaa
    41581 tgtctaaagc gaaaatcgtg ccagctgtat atcaaggtcc gttgacactt ggggatctgt
    41641 tcaagcgtca gagagtgaca gtgcgtttcg gcgaaccaat cgacttatca gatatcaaga
    41701 aaacggataa agaaggtatg gcggagatcg aacgacgaac acaagcagct tttgacaaat
    41761 tggacaaaga agtgaaccct gatttcaaat atgaagtcaa aaaaaaataa aatgataagt
    41821 ttatgcgtgg gcggtctttt gaatctactg tcctgttcag ttcagacttt ttcaatgaaa
    41881 acgagggaga gacgtcaagt ctgccctctt tttgcgttcc aatatgtaaa atagaagaca
    41941 ggtgtcatgt aatggatcaa agtgttataa taattagaag gacatttttt gaggtgattg
    42001 aatgcgtttt ttacatacag ccgattggca tatcggaaaa aaactacaag gttatgactt
    42061 gattgaagac cagcgtcatg tactatcttc tatactagat atcgcgaaag aagaaaaagt
    42121 agaggcaatc gtgattgccg gagacttata tgataggagt gtcccagctg ttgatgccgt
    42181 agaattatac aatgaattga tggtcgattg gaatttaaag gaaaagatcc cgatttttgc
    42241 tatatcagga aatcacgata gcagtacgag actttcagcg ggtacgccat ggttcagtta
    42301 ttcgaactat tttttgcgaa cacagctagc agaagcattt gaaccagtcg agtttaaaaa
    42361 cgtacaattt ttctttcttc cttactttga accaattgca gcgagattat attttgaaga
    42421 tgacaatatc cgaacgatca agcaagcggt agccaaggtg atagataaaa tgcaggagct
    42481 atttgattca gaaaaaaaac aagtattgat tagccatttt tttgtaatgg gaagtgtaaa
    42541 atctgattcg gaaacgaaaa tcgaagtagg cgggttggat tcgatccctg gtgaactact
    42601 tacaccgttt gattatgtag cactaggaca tttgcataat caagctgctt tgagacagga
    42661 taatgctcgc tatagcggtt ccccattgaa attctcttta tctgagatca accaaaaaaa
    42721 aggcgtatgg atcgttgacc tgacaacagg cctggagttg aattttaggg agatcgaacc
    42781 cctgcatgat attgaagaaa taacagcgag tttcaaagaa ttgctggatc ctgcctttta
    42841 tcagtccgtc aatcgggaga attacatcta tatctatctc actgatagaa cgatcatccc
    42901 gaatatgatg aaccagcttc ggcaaatata tcctcgtatt ttggggattg aacgggcaaa
    42961 cggtcgagca gaacaaacaa agcgcaaacg aaaagtacta gaaatgaaag atcctcaaaa
    43021 attagcagaa gcatttttta gtgaaatgac ggaagagcag ctaactgcaa accaagaaaa
    43081 atggctcgga gaaacgttgc aagaaatcat ggaaatggaa tgatcaagaa tgaaaccgaa
    43141 aaaattacaa cttaaaaatt ttggtccttt tatcaatgag accgtagatt tttcacgttt
    43201 gacagaagca ccgctttttt tgatcagcgg gaagacagga gctggcaaaa cgacgatttt
    43261 tgatgggatc accttcgcac tttttggtga aacttccgga agacttcgct ctggaaaaga
    43321 gatgcgttct ttgtttgcta caccagacga agaaacaagc gtgacttttt cttttgaaca
    43381 tcagcagatg agctatgaaa tcgaacgaaa accagaacaa gttttagcaa aacgaaaagg
    43441 aaacggaaca aaaaaacagg cagccaaagt aacgttgacc atttttgatg ggaaaggaaa
    43501 agaaataaaa caaatcacaa aacgtacaga agcagatcag ttgatcagag aactgatgaa
    43561 tctcgatgcg aaacagtttt ctcaaatcgt tttactaccc caaggagaat tccgtaattt
    43621 tttggtttca tcaagcagtg ataaagagac tgttttacgt catttattcg gtactcaatt
    43681 tttccaacag ttcaatgagc gattaaaaga aaaagcaaaa caacagcaac aaaaattgga
    43741 tcatttagag caagagctgc atcttctgca aaaaaggttt gttttagtca aagaagagga
    43801 accagcagca gggtttgaag ccgttttagc ccaatggaca aaccatcagg caatactcga
    43861 aaaacaaatc acggaagaaa aagaagctct aacggaactt caggaaaaac aaaagcaact
    43921 agaaaattcc tactatcgtt ttgaaagctt gaaaaaaagt tatgaagaaa aaacgatatt
    43981 aataaacaag caaaaggaat tagctgctca aaaagacgaa atagaggaaa agaaacgatg
    44041 gattgggtat tatgaattta cgcaacgatt agtcgaacca atccagcgcc tacaagaaat
    44101 aaaagttgaa aaaatagaac tgtcacaaaa aagtagtgag caaacaaaga aactagcgat
    44161 gactacgcag aattatgaag agtggcaaaa aaatgaagca aaccgcgtac gccgacaaac
    44221 aaaaatcaaa gaagctgctc aaaaactgca aaacaaacag atgatggtgc caattgtcga
    44281 atccttacgt agtaaaaaac aagacgcaga acaattaaca atttcattgg ataaagaaga
    44341 attgaatgcc gagaagctgt atcaaaatct cgctatctat caggaaagaa ctcgaattct
    44401 tcaagaaaat ttactggatc aggaaaaact gcaagaagat cgtcttgctt ttggacagtt
    44461 aaaatatcta gatgaaaagc agcaagaaat agaaaaacaa aaagcaaaag acactgggtc
    44521 gctcgcacag ataagagaag aactcaaaaa agcaactgaa gaaataacaa aaaatagtca
    44581 gctattgaaa gaacagacag aacaagcaga acagctgaaa agccaatggg caaagcagca
    44641 aattgctcgt cttcagcttt ttttgcgtcc aggggagcca tgtcttgttt gtggatcaac
    44701 ggaacacccc atacaacaat taaaacacga acagccaaat aaggaagata tcttaaaagt
    44761 agaacaacaa ctggcagaag ctgagtctgc tgtagaaaga actcagcaaa tcattgccaa
    44821 aagtgaagca catgaaaata atcttcaaca acaattatca gatttagaac aaaaaatcat
    44881 ggcaacgaat atacaattgg ctgaacaaga agaacacttg caacaggctt tgaaaaaggc
    44941 atttcctgag ataacagaac aaaaaacaaa aacaactctt gtagtaatcg aacaatcttt
    45001 agatagacga aaaagcaaga tggccaatgc aagaatagag ctggaagaaa taagacaaca
    45061 agcagaaaag ctcgaacaac aattagctgt ctacaaacag cagcagacag aaaaaaataa
    45121 tcagctccag caactgcaag gagaaatcaa aagtttagaa caacaattgc aagatacgga
    45181 tagtaactgt ttagaagagg agatacgacg acttgaaaaa cagttagaag aagactcgaa
    45241 tcaactagct gttgagcaga aagcaggagt gcaattgttg caagatcttc atacgcttcg
    45301 gacacagctt gatcttcaac atgaacaaat agaaaaaata gatgaaaaaa tagaaaagga
    45361 acaagaaaga atagctaaaa agttagaaag ccagtcgtat ttttcaacaa ttgaagaaat
    45421 ctgtgcattt gcacaacagc aagcacaata taaagaaaac caacgtacag ttacttctta
    45481 tcatgaagag caattagtga cagctgaccg gctgcgtcaa ttagaaaata tccagctaac
    45541 tgagacattc ccagatacag aagagatcag ccaacagtta gaagaaataa gacgtatgat
    45601 cgaaataaag caagaaaaga tatacggttt acaagaacaa aaaattagta atcaaaaaat
    45661 ctacgatgaa tgtctttcga tttatcacac aagccagacg aaattagatg agcttacgca
    45721 attacagcag ctttcgcaaa cattcaacgg agaaaatcct aagaagacta gtttggaacg
    45781 gtatgtgctt caggtttatc ttcaagaagt gttacaagta gcaaatgatc atctccaacg
    45841 tttaacgaaa aatcgttatc aatttgagct agcggatacc attggcagtt atcgagggaa
    45901 aaccggatta gaaatcaata tctatgatga tcaggcaggt atgtctcgaa gtgcgcatac
    45961 cctgtctggc ggtgagagtt ttattgcagc actttcttta gcattagctc ttgccgatgt
    46021 gatccagaca caagctggtg gtgtagcaat cgatgcattg tttattgatg aaggatttgg
    46081 gtcattagat gaagaagctt tggaaatggc aatggaagct ttagaaacga tcgaaagtga
    46141 aggaagaatg atcggcatca ttagtcatgt aagagaattg aaagaacgag tattacaaca
    46201 aataagaatt gatacagaag gtagcggaca aagcaaaata cgctatcaac ttggataaaa
    46261 agggagattg gtaactatga aatggagtat tccagaaaaa gtcattgcac gtggacgtca
    46321 atacttgcaa gaaggccgag tgttatcggt tgtccctgac caagaagaaa acgtgtggca
    46381 tgcagaagtc ttgggcagtg aattgtatat ggttgatttg gatggtacag caaaagagat
    46441 agattactgc caatgtccct attgggagga acataaatat tgtaagcata cagttgctgt
    46501 ggaactttat ttacggtcga aaaatctatc tcgtatcatg aaaaaagacc agccaatgct
    46561 agaaccggta aaagcaacaa gtgagggaga aatcattgca aaaggttttt ctcgtctaaa
    46621 aacacaaaac aatcctcaag cggtgcaacc tttgattatt gaataccaag tagaaacgat
    46681 tgagactaat cagtatcacc cagagctttc tattttggca ctttacttgc gtatcggttc
    46741 attggcatca ccgaaaaaaa catatatcgt aaaaaacatc tatgattttt tacaagctta
    46801 cacagaaaaa gaaacttaca ctgttaataa acagtaccag tttcgtctag ataaacgggc
    46861 gtttcaaaaa gaagatcaaa aaatactcac gcatcttgca ggaagtgctc agacgcatca
    46921 attattaggt acgaacggct tacaagtcaa aggaaaacta gataaaagat atctgcttct
    46981 cccagtagaa caagcccgct tcctgttaga gcagatgaat cagactacac gtttgcatct
    47041 gcagataaat gaacaaaacg atcaaggaat acaattttcc gatcaaaaca aacctttatc
    47101 attcaaagtg gaaaaatttg gagaagatta tttgctgcaa gcattgaatg attttgattt
    47161 tttctttatg cattatcagt ggggagttat ccaagggaca ttttattctc tgacgaaata
    47221 tcaacaaacg gtttatcaaa cttggaaaca attgattcgc cgattggaga aaccagaagt
    47281 agtgttcaag aaaaaagaat taccgtcttt gtttaaagag attatccctc tgctgtcaga
    47341 gatcggcgac gtagctattg cccctgcagt agaagaggaa gtagcagata tccccgtcga
    47401 atttattttc tttttccgaa aagcaaaagg aaaaatccaa gctcgagtcg atttcgtcta
    47461 tggcgaagtc atctattcga ctgacccgaa gcatgaggtc tcgacagaac aggcttttca
    47521 ggtgttacgt gacacagtag aagagaaacg agtacttgat ctattcagaa tgtatcgcta
    47581 ccagaaaaat gaaactggtt atgaacgtcc attgccaagc ggggaagaac tatatgcctt
    47641 tttccgcaca gaactatctg tcttccgtca gtttggtgaa gtcagacttg gaagaaaatt
    47701 gcgagagttg tatttagatg cgcataaaca tcaaccgaaa atcgaagtaa ccgagaccgg
    47761 ttcatggctc gatattcgat tcgatgtgac agggatagag gagcaagaaa tcgatcatgt
    47821 cctgcaaagc ttgctgagaa atgatgcttt ttatacatta gaaaatggtc aggttctttc
    47881 ttttgattca gaagaatttc aacaaacaag ccaagtgttg caacaattac gggaatcgat
    47941 acgtacagaa gaaggaacga tccatgtacc taaaaatcaa ggattgatca ttcaaaatca
    48001 attggaaaaa agcaatgcta cttttagtga atcgttccaa acgatggtac aagatctcat
    48061 tcatccagaa agataccagg cacagcttcc caaaggattg aatgcaacga tgagagatta
    48121 tcaaaagcaa ggttttcgat ggttgaagat gttaggtcat tatcagtttg gcggtatttt
    48181 agccgatgaa atgggacttg ggaaaacact acagacaatt gcctttttac tttcggaaaa
    48241 agaagaacgg aaaagcttct ctgctttgat cgtagcgcct gcgagcttaa tttacaactg
    48301 gcaggcagag gtgagaaaat tcgccccttc tttaagtatc caagtaatca atgggaataa
    48361 aaaagaacgt gaagaattac tggctaaaga cacagatatc cgagtgactt cttatgccag
    48421 cttaagacag gatctagcta attatcagtc gcaaaaaatt gattatttga ttcttgatga
    48481 ggcacaaatg gtcaaaaata gcagtacgaa aactgcacaa gcattgagag aattagctgt
    48541 acctcagcgg tttgcactga gtgggacacc aatcgagaat aatttagaag aattgtggtc
    48601 attgtttgca acgattatgc caggattttt cccgactaaa acaaaattca gggaacttgc
    48661 cgcagaagaa attgcgcaaa tgattcgacc gtttatttta cggcgagata aacaaactgt
    48721 gttgaaagac ttgccggaaa aaacagagat gaatctatat tctgcactta cagaagaaca
    48781 aaaaactgtt tatttagctt acttgcgtca aatgcgtgaa gaaatcacat caatggattc
    48841 tgaagcattc aagaaaaacc ggatcgggat acttgctggt ctgacaagac tgcgacaaat
    48901 ttgctgcgat cctcgtctgt ttattgaaga ttaccaaggc ggttccggca agctcgaaca
    48961 agtaaaagat ctactggtag ctgccaaaga gaacaaacga agagttttgc tgttttctca
    49021 atttacaggg atgctgacta tcttgcaaga agagttagcc gagctaggga tctcgacatt
    49081 ttatttaaga ggcagtacga aaccacaaga tcggttaagt atggtagacg catttaatgc
    49141 tggcgaaaaa gatgtttttc tgatttcctt aaaggctggg ggaactggat tgaatctcac
    49201 gggagcagat acggtcatct tgtatgacct ttggtggaat cctgccattg aagaacaagc
    49261 tgctggacgt gcacatcgga tcggacaaaa aaatgtggta gaagtgtggc gtatgatctc
    49321 tgaaggaacg attgaggaac gcatggattc actccagcaa gaaaaacgcg aactgttcca
    49381 aaaagtgatc caaggtaatg aagaacagtt gacgaaactg actgaagaag acatccgcat
    49441 gattttaagt gtaggagaaa tcgaggagta agagactcga aaaagcgttc agtaatgggt
    49501 aagaaagcct ttctaaagaa gcgattgttt atttgattta aaaaatagca aggaggctgg
    49561 gattccattt tatcccagct tccttgctat cattttttta tttctatttt taaaggttat
    49621 acaaagattg tcttcattgt ctctaacagc tgatcaaaag aagaaatctc gatatcgcaa
    49681 attggagtct gttcaatttt gcgttctcga tggttgaacc aaagcgcttg ccagttagca
    49741 ctttttgcac ctagaacatc attgtcgtaa ttatcgccaa cgtataaggt ctcttctgga
    49801 agcatatgaa attctttctc agctagctga aaaatctctt tttctggttt ttggaaacct
    49861 gttgcttgag aaatgagcat attgcgggaa ggaatccaat tgttcaattg aagttgcttc
    49921 agtttttttg tctgatggtc agtcggccca tttgtgataa ttcctaatgg gacattcttt
    49981 tccttcaaga aatcgagggt ttttttgacc tcctcatgca agcagatatt atcaagttct
    50041 tcctcgtaaa ttttttgaaa taagaggcca tcttcttccg taatatgagg gtagtctaaa
    50101 tcttttagtg attggctgat ccgatgtgct cgcatatatt ctagtgtcca atctcctgcc
    50161 attacttttg ggaagttttc atcactatga tggcggaacc ggatatatag tggatgcata
    50221 tctgcatctg aaacaagcgg aacgactctt ttgaccgcgt ttcgaaatgg ctgctgctga
    50281 tcatacatcg tatcatcaac atcaaacaca actgatttaa tcaaaatttt acacgccttt
    50341 cggttttcat tgattttttc acaaatcctt gactattgta acagaaaaaa ttgtctaaaa
    50401 aagctgataa ataaaggttt ttcttactat atttctattt ccttgacaga ataaggtttt
    50461 tatatttcag tttttttcac taaaaatcgt gaaacacgtc aataagtttg atgaacaaat
    50521 taatcattat ggtagaagtc gattgattta ttttaatgca atctctgtgg aattttcgaa
    50581 agatttattt ttttaataca gtctcaatat aactattcaa acataaaata acgttatttg
    50641 atttatttgt ttatagtaaa ttttatttag taatcattgc tttaaaatac tacgcttata
    50701 taacagagaa aataagcgtt ataataaaga acagtattat ttaaaatgac agaaaacatt
    50761 actattaaag aaataaaaaa cataaaaaat cttaagaaat cggtttcatt tagcttttga
    50821 gataaaataa tagtacagtt ttatacgctg tttcatatgt ttagaaaatt tgaattagat
    50881 ttgaaaactc taatttttaa atgataaaaa aagcgagaat gctggtttta ctgtatatta
    50941 accttagata actttcattt ttttaaaaaa attatgaaaa aaaggtagct atttaaaagt
    51001 tgattatgta taatagaaac agatgggaga ttattatgat cttctgttac aaaaaagtga
    51061 ttcttatcac gaaaaggagt ggtgcacgtt gttaacatta tatacttccc caagttgtac
    51121 ttcctgcaga aaggctcgtg cgtggttgca agaacatcag attccatttg ttgaacgtaa
    51181 tattttttca gaaccattga acagttctga attaaaagcg attttacaaa tgacagaaga
    51241 cggaacagaa gaaatcatct cgacacgttc caaagtattc caaaaactga acatggattt
    51301 agatgatctg ccgttacaag aattattgga acttgtgcaa aacaatcctg gattgcttcg
    51361 ccgtccaatc atgattgatg ataaacgtct gcaagttggt tttaatgaag atgaaattcg
    51421 tcggttccta ccgcgcgatg tacgacaatt agaattacgt caagcacaat tgatggctgg
    51481 attatagaag gataatacga aacttggaaa agactattac aaagatagtt tttccaagtt
    51541 tttttgtttt tacaaaaagt attcttgatt agatgtataa aaaggtagta gaagatgatg
    51601 attgcacgaa aaatagagag ggaaaattag ctgaaaagtc ggctatatag tattcgtctg
    51661 ccaaaaatgt tatagttaaa taagatagct tgaaaggttg aaaaatccgc tggttttatt
    51721 aaattcgctt aacagcgaga ttttttttct ttacatttaa gctgatttcg ctacaatgaa
    51781 tctatattaa acattgtggc aaagtgaggt gtagcaaaat ggaaatggaa catattaatg
    51841 aaaatacgat ccgtgtacta attggtcatg aagatttaga ggaacggggc gtttcatttt
    51901 tggatttact tggcaatcac aaagaaatcg aaaatttctt ttatagtatt ttggaagaag
    51961 ttgatatcga agaggagttc cgaggaagcg aagctgtcac tttccaagtt ttgccaaaag
    52021 gagacggatt agaactgttt atcagtaaaa atcttccgga tgaagaaatt tctcaatcag
    52081 aagattctac tgttgattca gaagatgtga gtgactttct tcgtcagcag attattggca
    52141 gcgatccgga ggaagaatta tctggaagcg ccctagaaga acaggaaaga caagcaactt
    52201 ttgcttttga agattttgaa caagtgatcc aacttgcaac agatgtcgaa ctagagtctg
    52261 cttggactga tttgtattta ttcgaagagc gctattacct agtcgttcac ttctggatgg
    52321 aaaatctcaa ccaagcggat gtagagaatc agattgctcg aattttggag tttgctgaaa
    52381 agagcgatcg tacaccagaa acattgaatg aatatggaca atgtctgatg gcgcgtaatg
    52441 ctatcgagcg aacgaaattt tattttgtat aaatcagcat tatagtaaga gactgtgaca
    52501 aaaattgtgt cgcagtcttt ttttcgtata aatgtgttca aaagcttgca tctgcggtaa
    52561 caagcccaac caaacgaaaa atattgggaa ctatttttgt ttagctgttc ttattacttg
    52621 atgcagaata gctttttcac gccctctttt ttcgtgtaaa taaattctta gacgtaaata
    52681 agttcagagg gagaaaaatg ctgcttgcaa tgaatgaata taataagtgc tgttttgcta
    52741 aacatgcaga aaaaggaaag aaatattatt gtcgtggctg tcgaaaaaga gtgattttga
    52801 aaaagggaaa gaaaaaatgt gctcattttg cccatcaaaa atcagataac tgttcggtct
    52861 ttagtgaaag agaatcaaaa gagcacttac agttaaagga atgcttcatg gattggctgg
    52921 gacagtcagt agaaccagta tttttggaag cctatttgcc gaggttgcgg caaaggccgg
    52981 atattttgtt ggcgaatcta gcaatagaaa tccaatgttc tagactgtct caccagagat
    53041 ttattgaaag aacccaaaat tatttgaata acagttacca agtatggtgg atacttggta
    53101 attcttttct tggacaatcg caattctcat tgatagaaaa aagttgctgc tactataata
    53161 gaaaaagagg agtgcattgc tggaaagctg atctcaagaa acaaaagctt tatttgtatc
    53221 atcatattac agagactgta tcagggcata tttccttttg cagtagctgc tggacttttt
    53281 ctagtaggga ccttaaagaa atattcacta gtaacgaaat taaaatgaac caaatgaaaa
    53341 aaatagaaaa agtgagtgaa gatgggaaga aatggctgac acgccaactt attcacaagc
    53401 aaaagaatac agtatccata caagaacaat gctacttgcg tcataaacat cttttgcatc
    53461 tatcatcgtg gatctatcaa aaaagtcggt ttttctttta tttacaagaa caggtttttc
    53521 tttatcgaat gttgtacgaa gaagccttgg aaaaccagaa agttcctgat ttcaactcat
    53581 ggctttgcca aataaaagaa cataaaaggg aatggctttt tcctatgatt gatgaagaga
    53641 tggtctatca gcagtttttt aacgaatgca tacacttgtc ttctttgaaa aaatagtaag
    53701 tataaaaata ggctaggaat cggttttcta tgtaaaacaa gatttagtta tgctaaaatt
    53761 gatggaagca gacacatgaa tgagtagaaa agttagatgc tgtgacatgt ggatgttaga
    53821 ctatgatcta ttttgataga tagagctaag ggaagaaaag gagtggattt catggaagta
    53881 aagcagttgc caaaacgaga agaattgcct gaaaatttaa cttgggactt gaccaagatc
    53941 ttttcaagcg accaagagtt tgatgagaaa tatttggaat tatcagaaga gttaaaacaa
    54001 tctgaaaaac acaaaggaac acttgatcaa ggcgcttctc aatttttaaa tgcgattgaa
    54061 ttcgtattga gggtttatcg ccaaactgaa gtcatttatg tatatgcgca ccttaaaaac
    54121 gatcaagaca ctggaaatac agattaccaa gcgctttatg caagagcaag cagtctgttt
    54181 tcgaaagtta gtgaagccgt ttcctggttt gaaccagaaa tattgcaatt gtcagatgac
    54241 cagatttggc aatatttcaa agaagaacca aaattggaag tctatcgcca ttatatccag
    54301 caaatagtag ataatcgagc ccatgtctta tctgctgagc aggaatctct tcttgctgga
    54361 gcaggtgaaa tctttgatgc ttcaagtgat acatttgctg ttttgaataa tgcagatcta
    54421 gtttttccaa cgattgaagg agaaaatggt gaaatagtcc aattatctca tggcgtgtat
    54481 ggtcagttgc tagaaagcac ggatcgaagg gtgcgcgaag cagcatttaa ggggttgtac
    54541 agtgtttacg aacaatttag aaatacattt gcttctactt taggcacaca tataaaagga
    54601 cataatttta aagcgaaagt ccgtaattac agctctgcca gagaagcgtc tttgagcaat
    54661 aatcatattc ctgaaagtgt atacgatact ttggtagacg tggtaaacaa gcatttgcct
    54721 ttgttacatc gatacatgga attacggaaa cgtttattag aagtggaaaa actgcacatg
    54781 tatgatcttt atacaccggt cttaggggaa gctccaatta cctttacgta cgaagaagca
    54841 aaagaaaaag ctttagaagc actgaaacca atgggtgaag aatacatggc catcgtagaa
    54901 aaagcattct ctgaacgttg gatcgatgtt gtcgaaaata aagggaaacg aagcggtgct
    54961 tattcttcgg gaagctatga cacaaatcca tatattttat tgaattggca tgatacgctg
    55021 gatcagctat ttacgcttgt ccacgaaatg ggacatagtg ttcatagtta tttcactcgt
    55081 tcgaaccagc cttatgtgta cggcgactac tccatctttt tagcagaaat tgcttcgaca
    55141 acgaatgaaa atatcctaac ggagtattta ttggaaacag aaaaagaccc tcgtgtacgg
    55201 gcttatgtac tcaaccatta cttggatggg tttaaaggaa cagttttccg ccagacacaa
    55261 ttcgctgaat tcgagcattt catgcatacg gaagatgaaa aaggtgtgcc attgactagt
    55321 gaatacctaa gtgatagtta tggtaaattg aatgcaaaat attatggtcc agcagtcgaa
    55381 gaagacccag aaattaaatt cgaatggtca cggataccgc atttttatta taattactat
    55441 gttttccaat actcgactgg cttttctgct gcttcagcac tggcgaagaa aatactaaac
    55501 caggaaccag aggcactaga gaactacttg gcttacctaa aagcaggtaa cagcgattat
    55561 cctgtggaag taatgaaaaa agcaggagtt gatatgacac aggctgcata tattgaagat
    55621 gcaatgtcga tgtttgaaca acgtctaaat gaattagaag aattgatcga tcgtttataa
    55681 ggctttctat ttttgatttt ctcgaataga aacgaaaaaa atacgtcggc tctcttgtaa
    55741 gggagtcgac gtatttttt
//
LOCUS       DACDLM010000012        53279 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.012, whole genome shotgun sequence.
ACCESSION   DACDLM010000012 DACDLM010000000
VERSION     DACDLM010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 53279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53279
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.012"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..1486)
                     /locus_tag="IV356_000725"
     CDS             complement(<1..1486)
                     /locus_tag="IV356_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014437.1"
                     /translation="MPEIEGIFSPKIGKKQLDFSSFPSVNRDYNLGDEVQILNIDFKE
                     LDFAVAVSNKPKALERVKKIYQENDQNIKNMIKKYRRDNSKVEDVLFNGTAKHDLNVY
                     MALGVALYCNSINQTDILVNIVRNSYQKILKISSETNPYYAMKYLGDNLLNDKKLMHN
                     TEELLSNLAAINFLFKTGSEDYFIDNVLKGAYGTAFYPLYNMKQHKAEQKDNKLEIKK
                     MKELLGIGFVKPNSKVTIASLATTNNDGKIVNGFDDSDIDILSKSYFSLYGDFADLMG
                     IDSYLVNNFEIKGSELNDIVYFVLISLYAIDQNTEYRQIDYLLVFYSLLYQFVLTRLF
                     KNAKEELILNSDYEIAKQIASIRKENKSEVIKLRKELSIASKENGRLESLVKSAKKEE
                     ELLKQEIKELKGIRKEFEQLRFENKVLKQLQEQEHRQSLNGKTEEPSLSEMIAYLKHK
                     NILLVGGHVNFQNKLTELLPNIKMFDVSENNGKILKNLNTCDAIF"
     gene            complement(1506..2399)
                     /locus_tag="IV356_000726"
     CDS             complement(1506..2399)
                     /locus_tag="IV356_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014438.1"
                     /translation="MRTHYIYLEDKIVDEIPAKSREQARKLFIEKYKEINGDSEVPKV
                     VVTVRKRQTKKRSTFHVSPDIYNLIERHRSEDNISISQYIATVIDELISGKYDYAFDF
                     EDEKDYKSVAVFQSDFEKLKNYAGRRNVNFARLLEEFYSEELGVGNEYKRETYAKLSH
                     KLSQALKEVTEVKAELDAKLEEVKKYQTERKNNMKNQVEFDEQKEFEKARKRYNKIMN
                     ELSYEHLTVHEELSEGTEKYTIADMVNEVETLLASFFENGHVNDEWRKEEPKRVNAYI
                     ARLKRFIDKYKENSDKFSKDK"
     gene            complement(2654..2974)
                     /locus_tag="IV356_000727"
     CDS             complement(2654..2974)
                     /locus_tag="IV356_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014439.1"
                     /translation="MKKKIVEGNVGVIILKDSTDYAKSMALKDEKVARMDKDLVEFLM
                     DDTERLKGDQFLSLMKDKGLNTYGLFDYKKLAIEWVKEGEIFFIEEWEGTENLVLHQY
                     LLKA"
     gene            complement(3007..4125)
                     /locus_tag="IV356_000728"
     CDS             complement(3007..4125)
                     /locus_tag="IV356_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014440.1"
                     /translation="MGNNSIYTPEMQNKIKRLVGLGWMTRGKLDSFSTIKYLLMDIYR
                     QNKQTGIHFLGYDKPEDAPFFVPSSAYRASTSGSMYNLDLFEEGAKMIEYDFNEAYSR
                     IMRNYPLPSNTYLKAKYNTDQAILRAINRPKVRPYENLKTYMFFLVNFEGTAKEGTYA
                     NPKSQSMFADYGENPKTANEPIWLSEIELTLILDYYDIKEMEVLDSHTFLTKKGLLKE
                     YFERIEPLKTDPDTLKLYKNLRTKVFGAIGQKSLREGETSTFDKYSMYNRAYSSMVAG
                     VFRDRMVRYEQKYVHSAYGLLKIRTDGLYFRSEVPEFEELYKLGVVKKKVHTISKEEV
                     EKALEFKNKGFENKGSFGNSKDEVKGVVIDDDFEFDFD"
     gene            complement(4154..4948)
                     /locus_tag="IV356_000729"
     CDS             complement(4154..4948)
                     /locus_tag="IV356_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014441.1"
                     /translation="MVAKKNTLKEASEKYQDMKRRGLIPKDKKGIWREFVKEVSSDRS
                     GGDFVGRYTAKGYSKRLRITVEYGTNESATELKQRYLDTRREASKKYNDFKSRGLIPK
                     KKKGIWREFFKEEDSNRNKGDFIGRYTAKGYTKNLGIKVEYGTGESSWELRNRYLNTL
                     LEKYKAELLELFDVNDFIEMAEKYGHEEGFMINDIMVIDNFTDLLALAKKARDLRETQ
                     MYLFRNKNGRNRRTESSEIEDYYDAFTHDLGAFVDEISGVMNKYRV"
     gene            complement(5001..5354)
                     /locus_tag="IV356_000730"
     CDS             complement(5001..5354)
                     /locus_tag="IV356_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014442.1"
                     /translation="MISENLSYENNKHLVKENKKVEDYKNMYIEMKKSPLCIQYKNDN
                     WKQVVEFVKPHSIRRVRRGKKKSELVNSGRAVIRVITKDYPVEYGDYILRLSYHAFVV
                     LKEEHFNEFFNLKSK"
     gene            complement(5456..5713)
                     /locus_tag="IV356_000731"
     CDS             complement(5456..5713)
                     /locus_tag="IV356_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014443.1"
                     /translation="MINEDFRSENKMIDISLIEKLLFSNKYTAKELATRWQISESAIK
                     AYRQNKGSVGWRDWKGISIGKAEDIMKREGLRSYTTSEKDK"
     gene            complement(5716..5940)
                     /locus_tag="IV356_000732"
     CDS             complement(5716..5940)
                     /locus_tag="IV356_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014444.1"
                     /translation="MNQRRRKRLEEISERLSELKDELEVIQEEEYKENIPKNLQGSER
                     YEKAEESVDQLEEAVDGLSDILELIEDIAS"
     gene            complement(6113..7156)
                     /locus_tag="IV356_000733"
     CDS             complement(6113..7156)
                     /locus_tag="IV356_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyhydrolase"
                     /protein_id="HAP9014445.1"
                     /translation="MKKFLVGILFTMGLVLLSPSVSAESSISMYRMYNPNSGEHLYTR
                     SVGERDNLKRYGWHYEGVAWQAPTSGTPVYRLYNRYNGEHFYTVDAGERDKISHTGWT
                     YEGVAFYSYNGANRVPVTRLYNKYVNWHHYTLDQNEKNVISKQGWKIEGTGWYAMPNS
                     VPNPTPAPSTEKVLNVPVVWQGNTMLCEGASLLEGLHYKGVATNQSLTSFVNYMPKAN
                     DNNPYHGYSGEWRHNVNGTYQGMMADPVVKWAKNVGGNAVNITGSGTNGIKNEIRNGN
                     PVVTWITYNYATPEFKQMPWGRAVWNGHVVLVDGFRNGAYHVVDPVFGAKWINASTYE
                     RAFNVTGMAVAVR"
     gene            complement(7335..7589)
                     /locus_tag="IV356_000734"
     CDS             complement(7335..7589)
                     /locus_tag="IV356_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3034 family protein"
                     /protein_id="HAP9014446.1"
                     /translation="MKKEELIDIFQIVERANNMGIMFFDRISLKMDLSVAHQEFNLRL
                     KALLNSDDVNFAHDVVGIQNHIDRENKRMGDEFLPRYSSL"
     gene            complement(7779..7994)
                     /locus_tag="IV356_000735"
     CDS             complement(7779..7994)
                     /locus_tag="IV356_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014447.1"
                     /translation="MKRDVFELYVLERLEDGMMAQEIIDEIDDMISRFGQLELNDGNK
                     NSVVLKKFWLNNFSYKDFIKEKANTLY"
     gene            complement(8046..8960)
                     /locus_tag="IV356_000736"
     CDS             complement(8046..8960)
                     /locus_tag="IV356_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014448.1"
                     /translation="MNNNEKILHVLDSFEIIQEELKKYRDVLEQRYDFVNQQKSNHMD
                     FILNMNDLKKKLVERKEQEKLIKAYFELGEKEVKNAMELNEERRVLDQLLEQLLVMFQ
                     KGRIDEDLIEEGLRKYPSNSGIGIVLKAIDEEEIEAFIPPEDFESAMEYIKYYSQGIT
                     AFREFDPEDVIHDLNNLKEWCESYGVDDSGLDYLISIMEIEEEMPDKPDPTDILELIH
                     EARNPIAYISRGYTVLEYYKPYISAMNHLRRVLREKREYRSVLNATNRLEKAVSELDA
                     YYREHYLQAGGMPRNTKANISRYIKKAE"
     gene            complement(8960..9859)
                     /locus_tag="IV356_000737"
     CDS             complement(8960..9859)
                     /locus_tag="IV356_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HAP9014449.1"
                     /translation="MWTVTLPFQPVSAPRPSARRNAADETNDVAEKRISTYYDKKYLD
                     YLKKIKSFIEDQDLLDDEFYSIVNDPMGAIMEVDFYYQIPKSYKKVYNIMKTTAPDLD
                     NLVKSAMDGIFNISAIRDSHITGLIAFKYNVANEGKTVVRIKRYSEFEWDTSEGLNGD
                     IWEATFDFKPVATPRPKSKFRGNGIITYYPKEYNDYLENIKNTLKEKDLVNDQLKKVM
                     NAPMGVIAQIDYFYQVRKDKKKLDSLMRTSQPDIDNLVKGTLDGIFNKEIGIKDSRVV
                     GLIAFKYNTFEKSKTNVRLQEMG"
     gene            complement(9859..10446)
                     /locus_tag="IV356_000738"
     CDS             complement(9859..10446)
                     /locus_tag="IV356_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014450.1"
                     /translation="MENNNDIRHFSIGERVTTVSELSKDYRDKEGTIISLNKNRRGVW
                     QYVVDLGDGVTVECKDSQLIRNNGSHSIEKAILVYPKVSSKIMNDWLLGKFGEYNKKE
                     IAEVIGKSYPTVLGYLKKITSKEAKIEDVLTVRELQSLIEYRNKQITNPEYLRKEDGL
                     LKQLEQVNKIRKMQKVAPLSLDTFKKIYLKEIKKD"
     gene            complement(10611..10802)
                     /locus_tag="IV356_000739"
     CDS             complement(10611..10802)
                     /locus_tag="IV356_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014451.1"
                     /translation="MVVNKEKVRKYVTLKIASVKYLEKRAKEEERARGKKVTVSELLE
                     ELIENDQTIRRAFTNRSIR"
     gene            complement(10875..11777)
                     /locus_tag="IV356_000740"
     CDS             complement(10875..11777)
                     /locus_tag="IV356_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014452.1"
                     /translation="MLLTLLGYLCLILAFFGAIAIIIGQFQTNNPIMRNIGIGIVIVT
                     FIVFNATKIFGSNDKQFGISGVNNSYAPDSLGRVVIDGTFENVTSYKNVSLTVKEDGK
                     KASDDVLATIKPSQSQFEVFYTVKENSPVHKLTLVFNVDGEEYYKDVKINKTSTKKII
                     ESAKKEVATEESTTESSSTVEAELPDKIDFDPEKVKSFESVSGSMADRFNTEVFKAIK
                     TVKLDTEKQMINVTLFNSVESMDQDKKVTVARELGKRVIGLYRGTAKPDSDGADLPVH
                     VVYEDGKVFGDSTANEALTIKLAK"
     gene            complement(11794..12270)
                     /locus_tag="IV356_000741"
     CDS             complement(11794..12270)
                     /locus_tag="IV356_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014453.1"
                     /translation="MPKRKEKKIPVFLSVSEMLSLQILLRKKIETIDEEVRNKRAMHE
                     QREALRERIHYFDDIHTKIYEARTNHEDESKLGLAQQRILEWLNTNTDQEPLRVISNL
                     FEFGTKHWFNAVEKDADLQEAFDTLSKDSKSMRDLLITYLNEHEFEQTKTKKKNKE"
     gene            complement(12286..12885)
                     /locus_tag="IV356_000742"
     CDS             complement(12286..12885)
                     /locus_tag="IV356_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HAP9014454.1"
                     /translation="MREKNKNSSRYLVATVVFVCVLIFLFDFLQIGKSIIGNTLSAKE
                     MVALGGLYEGHLFPNIFISIVSHINLYHLISNLLFLVVLEEALNDQYEWLTLLIVLII
                     SGFLGSLVPFLLQSNIVSMGLSGGIFGWIALFAIAYIHFDSKEHLLLSVFVLLIIGIL
                     LVSTFESGEANVLSHVIGFVCGMILGFILKNVSLIKQKN"
     gene            complement(12889..12942)
                     /locus_tag="IV356_000743"
                     /pseudo
     CDS             complement(12889..12942)
                     /locus_tag="IV356_000743"
                     /inference="COORDINATES: protein motif:HMM:NF019230.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(13593..14132)
                     /locus_tag="IV356_000744"
     CDS             complement(13593..14132)
                     /locus_tag="IV356_000744"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014455.1"
                     /translation="MNKRRILWLIAGMYLCIAVSGFTICRIINQLKNAIVYLGEIGYL
                     EDLKAGLQIMSWILFVLTVALVILTCENFSTIKKQIISNHNQETVKSGLEVDPEEEVT
                     EQAIKEQEEIDKKEIMSIYLSSGESFFHEIDSLKLSSQEIIDRWQNMSLDGELIVEDS
                     EGWSAYKKDEIVAITILFV"
     gene            complement(14271..14750)
                     /locus_tag="IV356_000745"
     CDS             complement(14271..14750)
                     /locus_tag="IV356_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014456.1"
                     /translation="MKTDLTRQAEKCLWHETNRMGVFGCFEVTIGWDGRERVDYITYS
                     VDNTVRCYEIKVTLSDLKSKAKQTFIGDYNYLVVTSDLWEKMLQDDTLMRKYYKQGVY
                     VFNEKYPSMISVKKARKQKVSLGTRSTVLESMVRSMNREVKKLYKVKPFWEIVEIPE"
     gene            complement(14747..15205)
                     /locus_tag="IV356_000746"
     CDS             complement(14747..15205)
                     /locus_tag="IV356_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014457.1"
                     /translation="MLTILKLYREGFNEKVSIGESIEYRGDKYIIIRILKINKHYFSK
                     SISLTVRVLVQKVGDLSDYYNCKREVIVDNRYDQSKDDKRIIKIGDIVFPEKGIAYEV
                     VSINSFRYEFVDLVVEYSVRLIVPWSKEEINEALKDERKSTFKVLEGEKK"
     gene            complement(15217..15846)
                     /locus_tag="IV356_000747"
     CDS             complement(15217..15846)
                     /locus_tag="IV356_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014458.1"
                     /translation="MIIVSSFLRWLTPYKYTDEVVVKRAKKKDKKAVLTPKQMLDHGI
                     LGVKVLEVNKPFESNSAREKLLGAEADVAYFYHDKSKHQIAIKFNPKSAWRYQARDDL
                     KRRKLRPMLYPEGKEAFDRTHIVPIGFHGTESDNRLLVGWNSNQNRVQINKFEKKVRK
                     FNERKTILWFADICKQPDGTAKWEAVIFDENGKKVMSETWHDKAKFVWQ"
     gene            complement(15843..17219)
                     /locus_tag="IV356_000748"
     CDS             complement(15843..17219)
                     /locus_tag="IV356_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAP9014459.1"
                     /translation="MAMKLLEKVKNRAEKAESILLDKEPNIKLNGKFSVNMLNTKAKD
                     PTDAIFGIKPDGTIAHFCISDTPHMLVAGTTGSGKSVLLNEILVTAICHAMPDELKLG
                     IVDPKRVEFGRYKKLPYMLADPITDMDEAYEFFEYLVILMNERYKLMEKAGVQNITQY
                     NKYAEKHGIEKFPYVILLVDEYSQLVGTHKEVEGLIVQLGQMARAAGIHVILATQSPR
                     STVVTGIIKANFPSRVCLMVASDLESRIVLDEGGGESLSPKGDMFIKLNGGNKIRAQG
                     AYISNEEIEAIFDHLRNTMPEPEYVDYRAIVAESRGEGGEDEDFGGIGKAPVRKSAKR
                     NLNTPLANSSSKEPSIEKKSTFALKLEKNKEEKEKQGAKTLEKLQAEKLEKVLKALDK
                     VDPEPQTSNNTNNEQPISSKTKPKTTDPKVSVKVTITTDNSEKKQVNGTTSPIMQKML
                     KAKKQVHK"
     gene            complement(17299..18561)
                     /locus_tag="IV356_000749"
     CDS             complement(17299..18561)
                     /locus_tag="IV356_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014460.1"
                     /translation="MSEKSIELKEYKRSDGEKYYPVANFSKSVYLVGRALVVSAIGIY
                     ILHWVTKVVQLLVDTLVSILVSLNDVNGTDDLGLKEMFKELLNAFFPNYLSYSYNVQS
                     FFAKLHLVDISILVLEAGTVFFVGYLVTLMFRHHYGEQRPFFDDMESRRLKREALEAM
                     DVKYDPNKIIGDETNNKKRKRNKTQLESDVLSTLKNIKISVHTRRDLSVNEDIREYIV
                     KIPQPKGKKVRETVLRQIQDLGSILTRATRGRAKFGEKEDEVSGDYFIFRASVNIERE
                     RKERVSTKNKETEKSTASIAVSNSQFAFPINLFADNSKNIQNQTEKARKYAETQKQSL
                     ELYLSSADVPASLTDMHVGNTSIEYLFTLSRTRKIQLSSMKEEIETYLHISGVIVRIN
                     AGRIQITLPLGENDRIPIDVPSMINSVF"
     gene            complement(18595..18921)
                     /locus_tag="IV356_000750"
     CDS             complement(18595..18921)
                     /locus_tag="IV356_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014461.1"
                     /translation="METISINGLDKSVANRIKKGNGYYLLKKGKYSVARELETMSIVY
                     VAKNHFDVEQAIFDPDSEIGKCVELSEKTVSTKGAMIIEREMLDEIRVIIPKDTQMCE
                     DSISDD"
     gene            complement(18941..19810)
                     /locus_tag="IV356_000751"
     CDS             complement(18941..19810)
                     /locus_tag="IV356_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HAP9014462.1"
                     /translation="MKKKKFSRSLLGILVLVAVGLSGKGYFQNNSTQEHDFQIKSSVQ
                     VGNKADSESKEFLGIRYDPNKYPNNIVNINDGKYTLTKEDHEALSEKGSQTFWVNYAD
                     LDQLGRAGNVEALITYDAVNSHSSKNVERPSFKSSVHIAGEYKDGVFDQERDTWVGKD
                     SNNEITQLEGYKGYLYNKSHSLAWSLGGDMEVHNLTLGTRAQNVGKNDQNGGMAYSET
                     IVRDAIYKNKNEKVLYKVDPIYKGNELVPRGSHVEAFSVNDNGKTVNLNVYVFNNQKG
                     ININYQNGTWVRD"
     gene            complement(20041..20847)
                     /locus_tag="IV356_000752"
     CDS             complement(20041..20847)
                     /locus_tag="IV356_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014463.1"
                     /translation="MRGDQTMSATTDMALEAVIKDNTGNVENVEDFSDIAINLSAWIS
                     AVGEENIEFEIKNMDDLKAKFPFIASKLSQFAEDKSWNELVSFSEKIYDITQEDECVS
                     WEMNNQYKKIDAFVKSRIEGTAFEFEGIDTAENWLNKESFIKSIADDLEKQWSKEDYA
                     EYLKTERDTEVKEKLTEVCLDEHIDPNIVKQEDYEVVIDKVPTDFEEVVKYIVEEALS
                     QYSSDEEVDEETVRTRVWQLVFDDKDYKYLSDQNSVNWSVRLLIDQNDIE"
     gene            complement(20935..21735)
                     /locus_tag="IV356_000753"
     CDS             complement(20935..21735)
                     /locus_tag="IV356_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014464.1"
                     /translation="MVGISKTALDSLAKLFSSRFDSAEFVEYLSQNESGKTLIETMKK
                     DYLNENDFPTWTNIEDATWDVVCTIYSPWVTIADFVLDKIGGDTYPDAKSLATSDFKT
                     FYGYLIGLIGNGIDLKVTPKQTPEEIEKEKGEVQMAYANDREKVKLLEGKLSEEELGK
                     MVQEINEDSNYFPELKVYQNDEDFFNEMFSNSPWEAVSKTNLGEWNFQDDLVAFSNDG
                     YLRSYSESEYRAELKTYETDILMSYLNLLESGQGELRDKVEELLKEEL"
     gene            complement(22074..23153)
                     /locus_tag="IV356_000754"
     CDS             complement(22074..23153)
                     /locus_tag="IV356_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP9014465.1"
                     /translation="MKNKILLFLTLICTLVLTIYPANQLYHQFKTKENVAEIQEKIEK
                     KQTPSKEEVAKKVEQIKSNSGNQGLDNTQKTDGGSFDIGEAEGKVNPYTGDVFSKNQT
                     KDFEPSTYSGAVGYVYIPKINVLELLFLGASQEHLYRGVAQMSATSLPLSGKGHQTVI
                     AGHRGGYTSPQFLYVDQLVAGDHIYIDYLGEKAVYTVFRTDVIRNYGQNSTLTDIPDL
                     DMLTLYTCHPYPQNYDRLLVRSLRDEKAKYITPQVTVGNTAYADAIDSEYVSDKTETV
                     TSSNDLFEDVDRANKELDGNNDLNIPEQGSVEMQDRTFAEKASSIFTGITNKHQKMLL
                     VIWTVIGALASLNVLILLIKEFRKA"
     gene            complement(23143..24000)
                     /locus_tag="IV356_000755"
     CDS             complement(23143..24000)
                     /locus_tag="IV356_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP9014466.1"
                     /translation="MKKKNIKLIILKIGMLLCLGVGLYPVITQAYTYYQTQQTLNSYK
                     EKYDEASEKENEEVFKRYSEVNRKRKDTEQTSVTIPEDNNNIPSNGNLQKDKLGELVG
                     EILIPKINVDLPIYDGVNDFQLSAGAGILTGTDYPTGGIGNHSVISAHSGIPNKKYFT
                     DLELLKLGDKFFIDISGKKLAYQVDRIKIILPTEFEDLLPVAGKDYVTLMTCTPVGDN
                     SHRLLVRGVSIPYQKSIVEKEKKKEDLKVKAQMNWYPIVVVGVLLIIAVIVIIKKIVA
                     KRRGMKNEE"
     gene            complement(24075..25910)
                     /locus_tag="IV356_000756"
     CDS             complement(24075..25910)
                     /locus_tag="IV356_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAP9014467.1"
                     /translation="MKSKKIFSNLMLFGTLLGVGLGASSISSSLGLGGQVAYAQQNYN
                     YQGTGTIHIHKVTNTNGDGNPVSDIDNKGKEIALPNGVKPLEGVEFSYVKLTKDEAKS
                     LGWTDSDTTKGQHIDDAKARLLLNKKYSEVSRMKTDSQGNIDIPIQVNTDDLTDNLYL
                     IVETGTVKGVVEEAYPMIVNVPELNGSDDQYFNYDVHVYPKNYFQLNSAELDKKDEDG
                     KALAGTVFELRKDDGSDQVVGTYKTDSTGKLTVDGLELGDYYFLETDLGTDANKTTYL
                     LDGKKFKFSVKRGETAKVVLDVTNYKRPVITKVIDKETVDTGEDVQYTLKPSIPGNIG
                     NYEKYVVKDVLGAELTYDSSEVIEGMTLDTDYSIERDGQTTNYVFTESGMDKLQKQFD
                     AGDRFFTILMNAHTNSKAKMDTPLKNDVSTIYNNGYEPEDETPVDHAYTIIGDHQFIK
                     TDGDTSKALSGAKFVVKNKIDPNKVTYLKQDPTTKAVTWIADKSKATEFVSGSDGKFQ
                     IEGLQYTYDVDFDKQGNPTITDKKINDYALEEVVAPSGYTPTRNDVPFVVSNDDASSE
                     VTDIKNLKTPETVRTGGIGTVVFLVVAGVAGTGLYVVYKREQHKA"
     gene            complement(25959..28349)
                     /locus_tag="IV356_000757"
     CDS             complement(25959..28349)
                     /locus_tag="IV356_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HAP9014468.1"
                     /translation="MKHEKTIILKSKIIYCFATLVMVLSTLIMPFSAIRAEADVTKPT
                     SAKFTETGVKTDGYIRVNMPNHPNEWMISSQFKDSHGNIGYCMDSELPSPTGSGAGSL
                     KYKGAGSDEFYRMFKGGFPSKTAKELGAGNDTEAWYATQLVSWVLAGNFKVSQIVWSH
                     PNHTAAETARVKKAFEKIYDYAKNGKDTPNTEFSITASKTADEGKYHTFTYKTASNKT
                     GNAKLTFTSAKPAGMKIYDADGKEITNNTVKLNSSFTIKVPVTTPSGTLSFKGTANVS
                     TTNPFTFDGRGVYQDAVVMITTSETKDSKSLSAKWTRAVGQVTVKKVDQDGNALKGAE
                     FTLTDNNNAKSVKTTGDDGLATFDLQQGLTYSLEETKVPEGYQGSFKKDGITVNTDGQ
                     EFSYTATNTIKKGKVKVKKVDQDGKPLANAEFTLTDDSSQTQAEKTDENGLASFDIVA
                     NKTYSLEETGVPTGYTGVFKQEGITVKDDGQTFEYTATNTLKKGLVKVHKVDQDGKPL
                     ANAEFTLTDEKGATQVEKTDENGLASFNIVANKTYSLEETGVPVGYTGAFKQEGITVK
                     DDGQTFEYTATNNLKKGVVKVHKVDQDGKPLADAEFTLTDEKGVKEVKKTDATGLATF
                     NIIANKTYNLEETKVPTGYTGAFKQEGITVKDDGQVFEYTAKNTLKKGVIKVHKVDDQ
                     GKALANAEFTLTDDKGVKVVQKTDSNGLATFNIVANKTYKIEETQNPNGYTGKWSKEG
                     ITVADDEQTFEYTVINHLVPETVRTGGIGTSAFLLVFLIAGLSMVLLYYREQHKAK"
     gene            complement(28619..29866)
                     /locus_tag="IV356_000758"
     CDS             complement(28619..29866)
                     /locus_tag="IV356_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014469.1"
                     /translation="MNMKKNSLAMVLFASAVLAGLSVPVTSHADEWTANTPDQIQITT
                     GQSSYAFKKGDTIWSTVEKLKSLGYKTTVAEFAELNNVDLAKGEQRTIPIGRTFNINK
                     DTLTVKEADGEVVSQTVQKDKPDPVENTEQENKKSETTKESEPTANTSDKTETSASSV
                     DGASSSNTNNSTSEKEASQGTSESSTTEADTGTSTNNSQSTSNDANESTSTSSSDQSQ
                     TGSSDETDSSTSPSKPEQPTNVVLGVPFISQGNTMLCEGTSLLEALHYKGVATNQDLM
                     TFVKSMPLSPDNNPNNGFSGEWRHNVDGTYQGMNPAPVVSWGVANGGNVVDISGSSVQ
                     GLKDEIVNGNPVVAWVTYAFEPAQHKSMFWGDAIWNRHVVAVDGFKDGFYHVVDPVFG
                     ASWINAGSFETAYNVSQLAVSVR"
     gene            30259..30675
                     /locus_tag="IV356_000759"
     CDS             30259..30675
                     /locus_tag="IV356_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014470.1"
                     /translation="MNKKRKLSVLITLVSMLAILSGILSIKIFNQINTSANTKNEIVI
                     ENTSNSKEISTTKNKDKSDETTTKNYLIKTVYFDERKTAILKDEEGSELKLPITVSDK
                     FNGTFSLQTAEGSPDNLKVGQTIILGKDEELYSFVK"
     gene            complement(30692..31429)
                     /locus_tag="IV356_000760"
     CDS             complement(30692..31429)
                     /locus_tag="IV356_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014471.1"
                     /translation="MADRKLEKLLEETWDPKEFSEFFMENFETDLAVIVKDALREQGY
                     PETANYININFTLYTENRGTWDFWANLANKELSDKSDTGIRNFFESNRDDYMYANNQN
                     KLNFRVEFDETPEEFIERQPPKENVAKVLEDRWNSDEIVSTISEQDGQYEPLVEAVRE
                     ELRLNKFPDVQNIDVSQIEINVNITNRLDYDSWADIALEKYIYSTLKEFIENRMNIMY
                     LQHPQYLNFGVEIATPLEEWKMEQGLD"
     gene            complement(31847..32410)
                     /locus_tag="IV356_000761"
     CDS             complement(31847..32410)
                     /locus_tag="IV356_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014472.1"
                     /translation="MQNHEITTAKKAIGILSIILILCCVVLFQKKNAYDNNVKELEDL
                     KSKQIEVVKNNQKVKAMQEAQYKELGNAEIKEQSRKFFNLFYNWNSWEKYTKNMKEIQ
                     KEFPQIVKSSPVDISGTMVGTGNSPISSYTADYYTTNQKGKMVELITQTRNTPTTATT
                     TIWRGVTSIGENQLFYLEDLDSYVRAE"
     gene            complement(32397..32924)
                     /locus_tag="IV356_000762"
     CDS             complement(32397..32924)
                     /locus_tag="IV356_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014473.1"
                     /translation="MNSKTKDAIIISLLSGMLLAMLVGILYFNKQNQDIEAEKHSVQI
                     ENELTFFKEVKPNEVDGLQRDLENDIQEMFKGSDRSKFANQSGEEFLRKLFIVTGKPP
                     VTNESSEQEKIEYYKPFTFKLTNFGIKTSSSGLYEALTDFEVQYNGKKVYDTTLTITL
                     NNDKKVTGGAFYAKS"
     gene            complement(32949..34280)
                     /locus_tag="IV356_000763"
     CDS             complement(32949..34280)
                     /locus_tag="IV356_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HAP9014474.1"
                     /translation="MVQFTGIAMSVITINPQVLHADGIATYDAQFNCTTEGSGSGTDS
                     DGNDTGSGAVTGDVAKNIEDIYKYMNGEYGLSGASIAGILGNWKQESGIDPRTVEGYY
                     GDGQREVDFIKQFTDGLMGIGYGQWTAGRHTALVDWSKKNNGGSWWTTEAQLDFMFKG
                     DGGFVGILKDYALNASDDVVENAVTFHKNWEISADSESAVIAVRGENAKEIWKYMKSK
                     GMDGAKDESKINKISGGSSTGDGSNNSSSSASGTVEDACATTDDANSGSGSIGKEGKI
                     NGKKGQVIANMTYEEALKKYGKAITLPKFKEPDWSTSPFQGELQGQCTELTWAYMSQL
                     YDGNQPTLGNGGYVWESYKSAGAKVTNKPIVGYAFSALDGWLWAVGSAGHTGVVIAVF
                     DDGSFLCANFNVPPTQAPTRGVSVTLIDGVDGSDNVHFFSGVGKAKFEIEK"
     gene            34406..34882
                     /locus_tag="IV356_000764"
     CDS             34406..34882
                     /locus_tag="IV356_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014475.1"
                     /translation="MTDKTSDLPKLDPKISQVKSKKDGKTKNAVKETSSLLLDIPMSS
                     FDEILDANTDETSVKIASHVGMNSQNDYFYNLLNSLRKLEDKKNQVIASKAPDLTTDL
                     DAEIIQIKQDERSVKSLLKTYFDGFDKELAPYSQAILTKPIQAPHISISLQKKSDD"
     gene            complement(34997..35229)
                     /locus_tag="IV356_000765"
                     /pseudo
     CDS             complement(34997..35229)
                     /locus_tag="IV356_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321015.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(35232..35549)
                     /locus_tag="IV356_000766"
     CDS             complement(35232..35549)
                     /locus_tag="IV356_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014476.1"
                     /translation="MKREEYKQRLNELLEEDETLTHGSPDEILYMIDNMVIFGGYELG
                     NRSVDHNILEFDDVSWEEILDWGILAVPETKTYISDTMVPFFEELDYKRLPKNENHIL
                     GGN"
     gene            complement(35564..36395)
                     /locus_tag="IV356_000767"
                     /pseudo
     CDS             complement(35564..36395)
                     /locus_tag="IV356_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36448..36777)
                     /locus_tag="IV356_000768"
     CDS             complement(36448..36777)
                     /locus_tag="IV356_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014477.1"
                     /translation="MKLEGSLQNRMMEGSTTNKEIVVGMGATELLYTDRNPYTVIEVK
                     SKNRILVQADGAINKATFPDQEWEYSRNPEGQILELVKTKNGWKVLKEDIHFYIGDRE
                     KYYDPSF"
     gene            complement(36905..37150)
                     /locus_tag="IV356_000769"
     CDS             complement(36905..37150)
                     /locus_tag="IV356_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014478.1"
                     /translation="MKEIEGIKKRNQERLELLNENRNRNRMFSYYESMRCLNKSRSEI
                     IESSKYKQLMEERVSLIQEIETESIFPDHSPKVRFYN"
     gene            complement(37241..37528)
                     /locus_tag="IV356_000770"
     CDS             complement(37241..37528)
                     /locus_tag="IV356_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014479.1"
                     /translation="MVEVEFGSKEWFEELNSMIKFPEKFTFYYNKRDNIIQVALLETK
                     GRLENTRWSMIKPSALRFHPKDLTAVVAVKEVQDSQEYYEVVKNLKDIWCK"
     gene            complement(37718..37900)
                     /locus_tag="IV356_000771"
     CDS             complement(37718..37900)
                     /locus_tag="IV356_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014480.1"
                     /translation="MAVNKILQVLIIDEFGGGEWFDVQSIDFEEEVVVIENIYGEVYS
                     YSLEGENVEDLRLIGE"
     gene            complement(37937..38737)
                     /locus_tag="IV356_000772"
     CDS             complement(37937..38737)
                     /locus_tag="IV356_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014481.1"
                     /translation="MSKDLRELKLRKKQYNQYFSSLLNKHIEEGLDHDFGKDEYCLYC
                     ERYNEKMSEYLQLKKEIQKLEKKVHAWKYKDSRSGYVESQNKPRKKKQAYVLKMVNGE
                     ELIVLAYSEEEVRELVETPVRKKVETINEIDDSQYNSIYIETSHGGYKKLATFLRSSK
                     VGIISKKDISAVTDSFCTLSVPKAYFQYDSKRFERLEKFCRPYTVLKTKKFNKTKRVS
                     IQLPTGQISLGEKDYLIKVGKELIIKVPEHLFKENFEIRETLVWKEEK"
     gene            complement(39355..39615)
                     /locus_tag="IV356_000773"
     CDS             complement(39355..39615)
                     /locus_tag="IV356_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014482.1"
                     /translation="MAYENLQLVVAEVSGDIYLTKVKDGIMDTNYRRVATDDVLSSST
                     EWFRKNEESAVHFEGIDGNIHSLFYTKDKEKAKKILDILKGR"
     gene            complement(39806..40174)
                     /locus_tag="IV356_000774"
     CDS             complement(39806..40174)
                     /locus_tag="IV356_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014483.1"
                     /translation="MWNNKLKTGLLLIVISCAMMVGMIIQREQSYFEVSANNVIERCH
                     YGQHFWTGEVRENIDREYVQRIVWDAYSIKDYPKSLTSRLFYSEKDNQKLSNLMMKKV
                     RKLAQNYLEEKEGNSPIDKN"
     gene            complement(40336..40866)
                     /locus_tag="IV356_000775"
     CDS             complement(40336..40866)
                     /locus_tag="IV356_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014484.1"
                     /translation="MSQNIGAVKQLIEKDLETTVQRLAERIHFANYQTISNWSSRNRN
                     PEEIPMKFFYRIGKEYGVDPIKIFEKTMIYYYHGTPNEVLEHLLEEAEEKSSILEISQ
                     NDKAIQVKCVDPTGKIIVGFDIERKSKIDFITQLTKINNLNILTLRPDHEQLFMSFKK
                     QLKEIQKRYNKVFSNA"
     gene            complement(40882..41247)
                     /locus_tag="IV356_000776"
     CDS             complement(40882..41247)
                     /locus_tag="IV356_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014485.1"
                     /translation="MSSLKDDYIQAKQEYEKIQMLKSEKVELFLTQKLAEDHIANLDA
                     KTLEEYDQQFNQTHHNIILLVDQAKRRLEKAEYELLDQGIICLDKGIRRYYSAELKKQ
                     NVDRHALKHEILELIMQRI"
     gene            complement(41253..41996)
                     /locus_tag="IV356_000777"
     CDS             complement(41253..41996)
                     /locus_tag="IV356_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014486.1"
                     /translation="MKEISANEAHIPQKNQVGIYKVLHGEGIYKIQLLTGYNNGANGK
                     WLKAKSIRELKTEVEKIRLGLTREEISRLSENSSFVIQKEKEKHLLHRELIIEKYYDV
                     DLPDQLRIIDEFSEKKWKSEIYPSLIQYKASGKPMYNYTGFLNYTQYKYAFRKLKGIK
                     QADIALYEMKKMDRLKLIQELVQNTWNQAIVELEKENGKILTNEYLIVNEIEELIGLF
                     SCENGEVFLKSSPIYSILDSPYQFIQVRR"
     gene            complement(42127..42849)
                     /locus_tag="IV356_000778"
     CDS             complement(42127..42849)
                     /locus_tag="IV356_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014487.1"
                     /translation="MKSTKWKIVLLSTAALITLTACGTTNSADNNKDTKSSSTVVTKN
                     SSTSASTTISSMTENNAEKYQKYEDINKGQKPEEVYTDFINTVKNDEDYGNDPLQNKN
                     LTIVLYKPDCPDCQKAESKIMQEIKEGFSYAPTLMHDITINKPAYEYHAVAVDITDGV
                     PEWIQNIPGLADENNQYHTPTVAVVTPKKVNGTLYWDVMGMTTNTTDEMIESTTKYYM
                     DLGAYKLYQQSEPVMDDQSKVK"
     gene            complement(42855..43100)
                     /locus_tag="IV356_000779"
     CDS             complement(42855..43100)
                     /locus_tag="IV356_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014488.1"
                     /translation="MKKIINQPTNHLIIEGVIFVTMYFTVGNGISNTIIQKNPQYLLF
                     SLYAWIVQMVWVSILMLLFYWIVRVILLVLNKRKKDR"
     gene            complement(43111..43695)
                     /locus_tag="IV356_000780"
     CDS             complement(43111..43695)
                     /locus_tag="IV356_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014489.1"
                     /translation="MDLKQSFYIWLYPDNPMSIMADIFVVSILLYLFYLIFFHNLIGY
                     MILDWKGMFDIERKPFANNQTYTVFESGDWEENEVDVIHEIGLALSGIQDADVLVSIT
                     TDTGYNAYEVFYLMYFIWRDGQEIINGRAEKTIISNTEISFCMGEGEMIVYKDGSANI
                     KTAFGDIDTSIKELREYVQNPYNFQYLAGRINLV"
     gene            43817..45400
                     /locus_tag="IV356_000781"
     CDS             43817..45400
                     /locus_tag="IV356_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014490.1"
                     /translation="MFILDDEIKKVKNPRIIPLLEEVRSSFYQGNYRSAIAVNYSALV
                     LDLIDKLSDLANIYEDITSKKILEDIARLRKSDPNSPKWEMELLEKAYSSTELIDSYE
                     YEDLKYIKDQRNYSAHPVVTYNGNTWELRDITKETCQDVIRKSYEIIFLKNPILGKKV
                     TIEIIQYASRIHAMSVTPEEFHSALKNSYLNKLSEKAKENLCKTAFKFVFQLPYGNEE
                     ADRDRESTFRLLNALIFDNKEFYLKILKEEISKYRFTAESREEINKSLGENQQITYTK
                     GVFLLTFIATHPELQHDFSDETIQNLQISINDFKPKQQVLTEIEYYYRLRSLAVLGSN
                     NEELQNHLNSLLDPILQQKMRVSSLPSSTLETIYNQYLYFGEKEMFIDFMIEHLTDAS
                     SFRLADKDMEVLPWIYNKLNQEQFNKLLYNLNGNNQFYKNSNFPPFISNLLDFYNQKF
                     QVNLRKHYSGLLYPNAVTMDQGFQLKDKELKNLYELAESKSDMYLDIIDNIINKSEDY
                     LRKEINSEKELLNYVHKIK"
     gene            complement(45657..45992)
                     /locus_tag="IV356_000782"
     CDS             complement(45657..45992)
                     /locus_tag="IV356_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014491.1"
                     /translation="MKQYLNEWKAIEGSLVTQRIKELPDCLEKDHLFQIREMLKKEQF
                     DPDQFLVVEYPTIGVYCCNHINDGKYFIIQEYGGQLTPFYTTWEMSEEGINNFPCESI
                     EDSISHTEC"
     gene            complement(46167..46661)
                     /locus_tag="IV356_000783"
     CDS             complement(46167..46661)
                     /locus_tag="IV356_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014492.1"
                     /translation="MNKLPEKNRVFRLKGDLSQFKIDENGQFFVWMRHEHCWCNPFEL
                     KKENEIRTKIANGEWDYLFRWEDESFIANDMDHAFVSFLDNTWGTWYDCYLEKLGFQN
                     IDIDAIECLKEVDQKYEEEPYYLLQQKLANNSVFQVEIWENEDGTYEGLAQEIPFSDR
                     KSSI"
     gene            complement(46658..46885)
                     /locus_tag="IV356_000784"
     CDS             complement(46658..46885)
                     /locus_tag="IV356_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014493.1"
                     /translation="MKPNIKILDRIFLGRDTEVILIQHEEGFEVSIGIQKLQKPHYCN
                     QLYKNFTDEEKARVFFNEVKGMREQYEVVEA"
     gene            complement(47052..49022)
                     /locus_tag="IV356_000785"
     CDS             complement(47052..49022)
                     /locus_tag="IV356_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014494.1"
                     /translation="MEIMGRSQLLNFKKKRKTKKEQKTRNSKVVNNTFVSDLTSLVGY
                     QFTPSYIRTGKRWGTIVKLVNTYGMNRNYGFGWMVKAIPEVRLEGVKAYLIEADKPVS
                     QKDQQEIMHENVGGSTNSYENNLEGKNSDAEISKTVMRIMDLNTASLLDSMANKIIDW
                     KLEILLVSDSPNKISEQLIKLQRLYDEKMYGLKLMSYGGDQRDLFDRLLSEPIGNVYE
                     YTSMSSDFAGNDHAIRKGLDDANGWAIGTMSTSYASGVAFMALDDSFTSKVLVASHKN
                     ATIKGYDEKISASSLWGQLIANNAMANHKRTFHIVLNKFDYFGDPTGRTFVAKPSLNS
                     VIEKVNLAEEGLNSLELFGNQKDIGDLYRRNLDKLTQIFYLLAGRTLDSATRVLLKKE
                     LGNFYISQKLWDINYEERSKLLVNSSDTMPVLGDFISYLTNAETKAKKSGTEKEVDRI
                     IVLKDTLRTALDSFSRMFNQRTTLKEIGKSDKLQFYYNLGDLRAEINVMEAQFLNTFD
                     FITSQAKKDDIVMIHGFDKLSIETVGLIKKRLTMLEEDGIRLAFLFDTIGSGEDNEYK
                     EDIETADIFNTDGKIYQSFESDFNYTIIGKMTSGELMKYEKKVAPARKGEDDQKLSVD
                     LRQYLTTGRSNKFQIRRPVDLTNNFVIGEFIL"
     gene            complement(49037..49903)
                     /locus_tag="IV356_000786"
     CDS             complement(49037..49903)
                     /locus_tag="IV356_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014495.1"
                     /translation="MADNSNYGFKHNLHQKPSETIVRVEWLEKHVNSTYSVTAKRLIV
                     SAIVVAVVVLGSIVYLVSDTIKLKFIFVPTLLMIIGFLILISQYMFIDPSSGSLISGS
                     IRLFKSVVNSARVSMGKKKPFRGTEILKVKQDGTIVYRDGSVALMFNLDGATSLTAFP
                     EEVMAQESKSIQYQNTRDRSLAEIKITSSQPQNTERQTRNMKIQKRNARSNKAVFDII
                     DQQERFVSEYIDGVKTTVIQYLILKSQSKMVLDEGVERLENYTSRGLYYSVTQLSAKQ
                     TKEILSDIYALK"
     gene            complement(49893..50126)
                     /locus_tag="IV356_000787"
     CDS             complement(49893..50126)
                     /locus_tag="IV356_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP9014496.1"
                     /translation="MREEKIVYPVIQNNQENMTSSQHLQEAQLVYQVNELPQTNETMS
                     KSISLIGLLIVAIVITVGVYRKLNVKGSISDGR"
     gene            complement(50138..52294)
                     /locus_tag="IV356_000788"
     CDS             complement(50138..52294)
                     /locus_tag="IV356_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014497.1"
                     /translation="MAKFKDITESINYVAETVPVVALSLKPQLLEVYKKEEKEAKAKK
                     AKAKVWKEFDALLTKDLPKKNYMVIEDVQKLNSEGVIDEDDAILDSEKYVVLLKSSLN
                     YVADLPEKFKEKLLAGVRFMDSSGQLLVIPDDPNVFESEVEEATDFYSAVEQLEVATN
                     GLERIAETFNSSEEVEFEAVAEDVPDEKEALFVDDNKPTEAENQEVSIEETQIQTETY
                     QQPKIDEKPESQSDKENYVYEAEKITSESDVPKNLDADFLEKNFEQIIADKFQPVVLD
                     EINDPVDLNEEMLSIPELKPLLFLAKESMNARISIANNKINSELNKTKEQLILKGKQM
                     LADELLRIEDATSLNGQNQFTNTLSVAKESYEAEASKIDDLVMEKSNIIRKDYDMAKQ
                     AYLDAELKKLEQRYDAEHLPEVKQQEDEYRKATEESLDQQYQEAIESIKNDALKQSQE
                     AKEVVVERIINSLKPEIEKSLTDVQEKTLEIVEKTKSENEAEFHDTKEKTTDVVVKYF
                     ANKEEVEKQVANNTKELETKLVEQQKTIEEYKDRMKEVKDLAEGYKLNSEKLAEQSEA
                     LREDLSRSRSDLAQMAEKTKSLAVATENQSSSKRDFTSKKMATIIAVAAMACGTILGS
                     SYFISHNNQQAQAQTQTSISRVENSIGTNTNSASTNSSYEATPTTEFKVGKDVVISID
                     GKTTKAEVISIDGEKAVVKTPDGNQYKIQAHLSDNN"
     gene            complement(52314..52535)
                     /locus_tag="IV356_000789"
     CDS             complement(52314..52535)
                     /locus_tag="IV356_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014498.1"
                     /translation="MVFDREKMLAHANEVLMSSLKGTELAKIMNMNVNQFYDYRNGSK
                     KIEKARLETLIKFEKAYVYMLDKQKRTID"
     gene            complement(52645..52983)
                     /locus_tag="IV356_000790"
     CDS             complement(52645..52983)
                     /locus_tag="IV356_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014499.1"
                     /translation="MFDSIKNLVSGMTPDMKTLVQVVLYFLAFVFSLKPGFTAMKFFG
                     DAKWGDGLKYVGAIIAIFIIPVITTVMLYTMGTKTGNDLNQKANIISALIPVVGIYLV
                     SKFPKNEQLG"
BASE COUNT        15392 a        10557 c         7079 g        20251 t
ORIGIN      
        1 gaaaaatcgc atcacacgta ttcaaatttt taagtatctt tccattattt tcgcttacat
       61 caaacatttt aatatttggt aatagttcag ttaatttatt ttgaaaattt acatgtcctc
      121 ccactaaaag aatgttttta tgttttagat aagctatcat ttcagacagt gaaggctctt
      181 cagttttacc atttaatgat tgtctatgtt cttgttcctg caattgcttt aatactttat
      241 tttcaaacct cagctgttca aattcttttc tgattccttt taattcttta atctcttgct
      301 tcaaaagttc ctcttctttt tttgccgatt tgactaaaga ttctaaccga ccgttttctt
      361 tactcgcaat acttaattct tttcttaatt tgattacttc agatttgttt tcttttctaa
      421 tacttgcaat ttgttttgct atttcataat cagaattcag gatcagttct tccttagcat
      481 ttttaaacaa ccgagttaaa acgaactgat ataacaaact ataaaaaact agcaaatagt
      541 caatttgtcg gtactcggta ttctgatcaa ttgcatatag agagattaaa acgaaataca
      601 caatatcatt cagctcgcta cccttgatct caaaattatt gactaagtaa ctatcaatac
      661 ccatcaagtc tgcaaaatct ccatacaaag aaaaatatga ttttgacaat atatctatat
      721 ctgaatcgtc aaacccattt actattttcc catcattgtt agtagttgct aacgaagcaa
      781 tagtgacttt tgaattgggc tttacaaatc ctatacctaa tagttctttc atctttttaa
      841 tttcaagttt gttatccttt tgttcggctt tatgctgttt catattgtaa agcggataaa
      901 atgctgttcc gtaagcacct tttagtacgt tatctataaa ataatcttca gaacctgttt
      961 tgaatagaaa gttaatcgca gccaaattag ataacagctc ttcagtgttg tgcatcaatt
     1021 ttttatcatt taataaatta tccccaagat atttcattgc ataataaggg tttgtttcgc
     1081 tacttatttt taatattttt tgatagctat tcctcacgat attaaccaaa atatctgtct
     1141 gattaattga attacagtac aaagccactc ctaatgccat ataaacattc aaatcatgtt
     1201 ttgccgtacc gttgaataaa acgtcttcaa cttttgaatt atctcgtcta tactttttga
     1261 tcatattttt gatattttga tcattctctt ggtatatttt tttcactcgt tccaatgcct
     1321 tgggtttgtt ggaaacagca acagcgaagt ctagttcttt gaaatcaata tttagtatct
     1381 gtacctcatc acctagatta taatctctat ttacgctcgg aaaactgctg aaatctaact
     1441 gttttttacc tatttttggc gaaaatattc cttcgatttc tggcaaatgt aatcacactc
     1501 tctccttatt tatctttaga aaatttgtca ctattctcct tatatttatc aataaacctt
     1561 tttaatcgag caatataagc gttaaccctt ttaggttctt cttttcgcca ttcatcgttt
     1621 acgtgaccat tttcaaagaa agaagctaaa agagtttcca cttcattaac catatctgcg
     1681 atcgtatatt tttctgtacc ctcactcaat tcttcatgaa ctgttaagtg ttcatagcta
     1741 agttcattca taattttgtt atagcgtttt cttgcttttt caaattcttt ctgttcgtca
     1801 aattccactt gattcttcat gttgttcttc ctctctgttt gatatttttt cacttcttca
     1861 agtttagcat ctagttccgc tttaacttct gtcacttctt taagcgcttg ggataactta
     1921 tgagacaatt tcgcataagt ttctctcttg tattcatttc ctactcccaa ctcttcggag
     1981 tagaactctt ctagtagtct tgcaaaatta acatttctcc tgccagcata gttttttagc
     2041 ttctcaaaat cagattgaaa gacagcaaca cttttgtaat ccttttcatc ctcaaaatca
     2101 aaagcatagt catactttcc tgaaatcaat tcatcaataa ctgtagcaat atattgagag
     2161 atagaaatat tatcttcact tctatgtcgc tctataagat tatatatatc agggctgaca
     2221 tgaaacgtac ttctcttttt tgtttgcctt tttctaactg ttacgaccac ttttggaact
     2281 tcactatctc cattgatctc tttgtatttt tcaataaata attttctagc ttgttctcga
     2341 ctttttgccg gaatttcatc tacaatttta tcttctaaat aaatatagtg tgttctcata
     2401 cattcgtcct ctatcttctt tactctcaat cttcatgatc ttagttctta ccttgtttac
     2461 tcttaaacct ttcaaaaaaa tctagtcaaa atcaaacttg aaatcatcgt ctatcacaac
     2521 acccttaact tcatctttag agttcccaaa ggaaccctta ttttcaaatc ctttattttt
     2581 gaatgatgat ggttatggaa aacatccttt gaaattctga caagcataac tagtcagaac
     2641 tgttttactt agattaagct ttcaaaagat actgatgaag aactaagttc tcagtacctt
     2701 cccattcttc aataaaaaat atttctcctt cttttaccca ctctatagct aatttcttat
     2761 aatcaaataa accatatgtg tttaagcctt tgtctttcat taaactcaaa aactgatccc
     2821 cttttaatct ttctgtatca tccatcagaa attcaactaa atctttatcc atgcgtgcaa
     2881 ctttttcgtc ttttagtgcc attgatttag catagtcagt tgaatctttt agaataataa
     2941 cacctacatt tccttccaca attttcttct tcatatttac ctcctaccat cttttccaaa
     3001 gagtatttag tcaaaatcaa actcgaaatc atcgtctatc acaacaccct taacttcatc
     3061 tttagagttc ccaaaggagc ccttattttc aaatcctttg tttttaaatt ctaaagcttt
     3121 ttcgacttct tctttggata ttgtatgaac ttttttctta actactccaa gtttatacag
     3181 ctcttcaaac tctggtactt cggatctgaa atacaatcca tcagtccgaa tttttaatag
     3241 cccatatgcg ctatgaacgt atttctgttc atatctaacc atacgatctc taaatacgcc
     3301 tgctaccatg gaggaatacg ctcgattata catactgtat ttatcgaagg tgcttgtttc
     3361 tccttctctt aatgattttt gtccgatagc accaaatact ttcgttctaa gatttttata
     3421 aagcttcaac gtatcaggat cagtttttaa tggctcgatt ctttcaaaat attctttgag
     3481 taatcctttt ttcgtcaaaa atgtgtggct atctaggact tccatctctt taatatcata
     3541 ataatcaagg ataagtgtta gctcaatctc cgataaccaa ataggctcat tagctgtttt
     3601 gggattttcg ccataatccg caaacatcga ctgtgatttt ggattagcat atgttccttc
     3661 tttggctgtt ccttcaaaat taaccaaaaa gaacatatac gtttttaaat tttcatacgg
     3721 tcttactttt ggtctattta tcgctctcaa aatagcttga tctgtattat attttgcttt
     3781 caaataagtg tttgacggca aaggataatt tctcatgatc ctcgaatagg cttcgttgaa
     3841 atcatattcg atcatctttg ctccttcctc aaacaaatcc aagttataca tgctaccgga
     3901 ggtactggct ctataggctg aacttggaac aaagaaaggt gcatcttccg gcttatcata
     3961 acccaaaaaa tgtattcctg tttgcttgtt ctgacggtaa atgtccatca aaagatattt
     4021 gatcgtacta aaagaatcta attttcctct tgtcatccac cctaatccga caagtctttt
     4081 aattttattc tgcatttcag gtgtgtatat gctattgttt cccatttatc tgctcatctc
     4141 cggctttttt attctagacc ctatatttgt tcattacacc acttatctcg tctacaaagg
     4201 ctcccagatc gtgtgtaaag gcatcgtagt aatcttcaat ctcactcgat tcagttctcc
     4261 ggtttcttcc gtttttattt ctgaatagat acatctgcgt ttctcttaaa tcccttgctt
     4321 ttttcgcaag tgctaataaa tccgtaaaat tatcaataac cataatgtca ttgatcataa
     4381 aaccttcttc atgaccatac ttttcagcca tctcgataaa atcattaaca tcgaacaact
     4441 ccaataattc tgctttatat ttctctaaca atgtatttaa atagcgattt ctcaattccc
     4501 atgagctttc accagttccg tattcaacct tgatccctaa attcttagtg tagccttttg
     4561 ctgtgtatcg tccaatgaag tctcccttat tccgattgct atcttcttcc ttgaaaaact
     4621 cacgccaaat tccctttttc tttttaggaa tcagacctct gctcttgaaa tcattatatt
     4681 tttttgaagc ttcccttcgt gtatctaagt acctttgctt cagctctgta gctgattcat
     4741 tcgttccata ttcaacagtg atccttaatc gtttgctata gccttttgct gtatatcgtc
     4801 caacaaagtc accgccactt cgatcactac tgacttcctt aacaaattct ctccatatac
     4861 cttttttgtc tttcggtatt aatcctcgtc ttttcatatc ttgatatttt tcagaagctt
     4921 cttttagagt attctttttt gctaccatgt catcacctcg caatttagtt aactttatac
     4981 acgtctacaa aaaaatatga ttacttactt tttaaattga aaaactcgtt gaaatgctct
     5041 tctttcaaca caacaaaagc atgataactt aaccttaaaa tataatctcc atattcaact
     5101 ggataatctt tggttataac tctaattacc gctcttccgc tatttacaag ttcacttttt
     5161 ttcttccccc ttcgtactct tcgtatacta tgaggtttta caaattcgac tacttgcttc
     5221 caattatcat ttttatattg aatacacagt ggtgattttt tcatttctat atacatgttc
     5281 ttataatctt ctactttctt attttcttta actagatgtt tattattctc ataagacaaa
     5341 ttttcgctta tcatttaata tttcccttcc tttttttgca ttatatttag caaacattca
     5401 ccatttgaat ttgacatagc tttaagacag atattttatc ttttcaaaca ttaagttatt
     5461 tgtctttttc agaagtggta taggatcgaa gtccttcacg tttcattatg tcttctgctt
     5521 ttccaatgct gatccctttc caatcacgcc atcctacgct tcccttattt tgacgatagg
     5581 ctttaatagc tgattcggat atttgccatc ttgtagccag ctcttttgcg gtgtacttat
     5641 ttgagaaaag taacttctct atcagtgaaa tatcaatcat tttattctca ctcctgaaat
     5701 cttcattaat catctctagc tagctatatc ttcaatcaat tctaatatgt cggataaacc
     5761 atcaacagct tcttcaagtt gatcaacgga ttcttctgct ttttcatatc tttctgatcc
     5821 ctgtagattt ttaggtatat tttctttgta ctcttcttct tgaattactt ctaactcatc
     5881 ctttagctcg gaaagtcgct cgcttatttc ttctaacctt tttcttcttc tttggttcat
     5941 caaaatcacc tcttcgcata atctctacga ttttaatata ccacttttgt gtactacatt
     6001 caatattttt tgttatagat tcgtattaca aaaatttcct ctaaaaaaat aagagcctat
     6061 ttaccatttc agtaattaag ctcttatttc atttagttga taattctatc aattaacgta
     6121 cagcaaccgc cattccagtc acattaaatg ctctctcata cgtgcttgca ttgatccatt
     6181 ttgcgccaaa tacagggtca acaacatggt atgcaccatt tctgaagcca tccacgagaa
     6241 ctacatgtcc attccatact gcacgacccc aaggcatttg tttgaactct ggcgtagcat
     6301 agttataagt aatccaagtt acaaccggat taccattgcg aatttcattc ttgattccat
     6361 tcgttcctga accagtgata ttgacggcat taccgccaac gttttttgcc catttaacta
     6421 ctgggtcagc catcatgcct tgatacgttc cattaacgtt atgacgccac tctcctgagt
     6481 aaccatgata aggattattg tcattagctt ttggcatata gtttacaaaa ctggttaagc
     6541 tttgatttgt ggctacacct ttgtagtgta aaccttctaa taaagaagct ccttcgcata
     6601 acattgtatt tccttgccat acaacaggaa cgttcaacac tttttcagtg cttggagcag
     6661 gtgtaggatt tggtacactg tttggcattg cataccagcc tgtaccttca atcttccaac
     6721 cttgtttact aattacgttc ttttcatttt gatctaacgt gtagtgatgc caattcacgt
     6781 atttgttata taaacgtgtt acaggaactc tatttgctcc gttgtaggaa tagaacgcaa
     6841 caccttcgta cgtccatcct gtgtgtgaaa tcttatctct ttctccggca tcaactgtgt
     6901 aaaaatgttc accgttatac cgattataca aacgataaac aggagtacca cttgttggag
     6961 cttgccatgc gacaccttcg taatgccatc cataacgttt cagattgtct ctttctccaa
     7021 cgcttctagt gtatagatgc tctccgctat tgggattata catacgatac atggaaatag
     7081 agctttctgc tgaaactgaa ggtgataata atactagccc cattgtgaat agaattccta
     7141 ctaaaaattt tttcatttga ttttacccct tttcattttt tattgtcatt attgcatgaa
     7201 aattattcgt aagattgcca attacataaa cgattgtttt aagatcataa tcgttgttgt
     7261 cttaaattca ttcctccttt ccaattcaag agtacctatc aataatgaca catactcttg
     7321 aatctttcgc caaatcataa acttgaatat cttggtaaga attcatcacc catacgtttg
     7381 ttttctctat ctatatggtt ctgtatacct acaacatcat gagcgaaatt aacatcatca
     7441 gaattcaaca aggcttttaa tcgcagatta aattcttggt gggcaacgct taaatccatc
     7501 tttaaagaaa tacgatcaaa aaacataatt cccatattat ttgctcgttc aacaatttga
     7561 aatatatcta ttagttcttc ttttttcata actgctcttc cttcctttaa cttgttaatc
     7621 taacttgctt acaaatatat cctaccacat ttgtgtacta tccgtcaata tttttttgtg
     7681 tataaatgtg tattataaaa caaataattt tacacaaaca aaaaagagcc taactgctct
     7741 tagcaataag ctctcatcac tgctcctcgt gaatttagtc agtacaatgt atttgccttt
     7801 tctttgataa aatccttata cgaaaaattg ttcaaccaaa atttttttag cactaccgaa
     7861 tttttgtttc catcattcaa ctccaattga ccaaatctgc tgatcatatc atcaatttca
     7921 tcaattatct cttgtgccat catgccgtct tctagacgtt ctaatacgta caattcaaaa
     7981 acatcccttt tcattcaaaa tgcccctttc aggttacctt ttgccatttt atgggctaac
     8041 tccgcctact cagctttttt tatataccta ctgatatttg ctttcgtatt tcttggcata
     8101 ccacctgctt gcaggtaatg ttcacgataa taagcatcta gctctgaaac agctttttct
     8161 aatctattcg ttgcattcaa cactgagcgg tattcacgtt tttcccttaa tacacgtctt
     8221 aaatggttca tcgctgatat ataaggctta tagtattcca atacagtata tcctctagaa
     8281 atataggcaa ttggatttct agcttcatgg atcaattcta aaatatctgt tggatcaggc
     8341 ttatccggca tctcttcttc gatttccata atactgatca agtagtccaa tccggaatca
     8401 tcgactccat aactttcaca ccattctttt aggttgttca agtcatgaat aacatcttca
     8461 ggatcaaact ctctaaaagc agtgatccct tggctataat attttatata ttccattgcc
     8521 gattcaaaat cctctggcgg tatgaaagct tcaatttctt cttcatcaat cgctttcagc
     8581 actattccga tacctgagtt tgaaggatat tttctcaatc cttcttcaat taaatcctca
     8641 tctattcgtc ctttttgaaa catcaccaat aattgttcta acagctgatc taaaaccctg
     8701 cgctcttcat taagttccat tgcattttta acttcttttt caccgagttc aaagtaagct
     8761 ttgatcaact tttcttgttc ttttcgttca actaatttct tcttcaagtc attcatattg
     8821 agaatgaaat ccatgtgatt actcttttgc tgattgacaa aatcatatct ttgttccaaa
     8881 acatcccgat atttctttag ttcttcttga attatttcaa agctatcaag tacatgaaga
     8941 attttttcat tattattcat cagcccatct cctgtagtct cacgtttgtt ttcgactttt
     9001 caaaagtatt gtatttaaaa gcaattaacc ctacaaccct gctatctttg atgcctattt
     9061 ccttgttaaa aattccgtcc aatgttcctt tgactaaatt atcaatatcc ggctgtgaag
     9121 tacgcatcag tgaatcaagc tttttcttat cttttctcac ttggtaaaaa taatctatct
     9181 gagctataac ccccatagga gcattcatta cctttttcag ttgatcattt accaaatctt
     9241 tctctttaag cgtattcttg atattttcca aatagtcgtt gtactctttt ggatagtaag
     9301 tgataatccc atttcctcta aatttagact ttggtcttgg cgttgctact ggtttaaaat
     9361 caaatgtagc ttcccatata tctccgttca atccttcaga agtatcccac tcaaattctg
     9421 aatatcgttt gatcctcaca actgtttttc cttcgttcgc cacattatat ttaaaagcaa
     9481 ttaagcctgt gatatggcta tctcgtatag ctgagatgtt aaaaatacca tccatagcac
     9541 tttttactaa attatctaaa tctggcgctg ttgtcttcat aatgttatag acttttttat
     9601 agctttttgg tatctggtag taaaagtcca cttccataat tgcgcccata ggatcattta
     9661 caatcgagta aaattcatca tctaataaat cttgatcttc gataaagctc tttatttttt
     9721 tcaaataatc aagatacttt ttatcatagt aggttgaaat ccttttctct gctacgtcat
     9781 tagtttcatc agcagcattc cttcttgcac ttggtcttgg tgcagataca ggttggaacg
     9841 gtaaagttac agtccacatt agtctttttt gatctctttc aaatagattt ttttaaaggt
     9901 atcaaggctt aaaggagcta ccttttgcat cttccggatt ttatttactt gttccaattg
     9961 tttcaataga ccatcttctt ttctaaggta ctcaggattt gttatttgtt tattccgata
    10021 ctcgattaat gattgaagct ctcttactgt taaaacatcc tcaatttttg cttctttact
    10081 cgttatcttt tttagatacc ctaatactgt tggataagat ttgccgatca cttctgcgat
    10141 ttctttttta ttgtactcac caaattttcc aagcaaccag tcattcatga tcttacttga
    10201 tacttttggg tatacaagaa ttgctttttc aatggaatga ctgccattat ttctgatcag
    10261 ttgactatct ttacactcaa ctgtaacgcc atcacctaaa tcaacaacat attgccaaac
    10321 gcctcttcga ttcttattaa gagaaataat cgttccctct ttatctctat aatcctttga
    10381 taattcactt actgttgtaa ctctttcccc aatgctaaaa tgtctaatat cattattgtt
    10441 ttccacttat tatccctcca atattgctgg ttatctcttc ctctgacaag gaactatata
    10501 tcgtataaag aattttaaca ttattcggaa tgagtgtaaa gaaactttat ataaaaagag
    10561 tgatttagtc taagaccaaa tcactctttc tttttttatt aattatattg ttatctgata
    10621 gacctattag taaatgcacg tcttattgtt tgatcattct cgatcaattc ttctaacaac
    10681 tctgaaactg ttactttctt acctcttgct ctttcttctt ctttagctcg cttttctaaa
    10741 tatttaacag aagctatttt taaagtcaca tactttctaa ctttttcttt atttactacc
    10801 atcagctatc atctccaagg tgtcacacct atatattatt ggtgtgacac catttgttta
    10861 ttataacttt ctggctattt agccaattta atcgttaatg cttcgtttgc tgtagaatct
    10921 ccaaaaactt taccgtcttc ataaactaca tgaactggca aatctgcacc gtctgaatct
    10981 ggtttagcag taccacgata caaaccaatt actctttttc ctagttctct tgcaaccgta
    11041 acttttttat cctgatccat agattcaact gaattgaata aggtaacatt aatcatttgc
    11101 ttttcagtat ccaatttaac agttttgata gctttgaaga cttcagtgtt aaaccgatca
    11161 gccatagaac cagaaacaga ttcaaacgat ttgacttttt caggatcaaa atcaatttta
    11221 tctggtagtt ccgcttcgac agtagaactt gattcagttg tactttcttc tgtagctact
    11281 tcttttttcg ctgattcgat aatctttttc gttgatgttt tatttatttt tacatcttta
    11341 tagtattctt ctccatcaac gttaaaaacc aatgtcagct tgtgtacagg gctattctct
    11401 ttaactgtat aaaacacttc aaattgtgat tgagacggct taatagtagc gagaacgtcg
    11461 tctgatgctt tcttgccatc ttccttcact gtcagcgaaa catttttata actcgttaca
    11521 ttttcaaatg ttccatctat tactaccctt cccaaagaat ctggagcata actattatta
    11581 actcccgata taccaaattg tttatcgtta cttccaaaaa tcttagtggc attaaacaca
    11641 ataaaggtta caatcacaat tccaatgcct atgttacgca taatcggatt atttgtttga
    11701 aattgaccaa taattatagc gattgcccca aaaaaagcaa gaattaaaca taaataacct
    11761 aacagggtta atagcatgat tcatcacaac tttctattct ttatttttct ttttggtttt
    11821 cgtttgttca aactcatgct catttagata agtaatcaat aaatctcgca tggatttgct
    11881 atccttactt agcgtatcaa acgcttcttg taagtcagca tccttctcta cagcattaaa
    11941 ccaatgcttc gttccaaatt caaaaagatt actaatcact cttaacggtt cttgatcagt
    12001 attcgtatta agccattcaa gtatccgttg ttgagctaat cctaatttac tttcgtcttc
    12061 gtgatttgta cgtgcttcat agattttagt gtgtatatca tcaaaatagt ggattcgttc
    12121 tcttagcgct tcacgttgtt cgtgcatagc ccttttattt ctaacttctt cgtctattgt
    12181 ttcaatcttt tttcttaaca gtatttgaag tgataacatt tctgagacag acaaaaacac
    12241 tggaattttc ttttcttttc tttttggcat ttttagcact cccttttaat tcttttgttt
    12301 gatcaatgaa acgttcttta gaataaatcc caagatcatt ccacagacaa atccgattac
    12361 atgtgacaag acatttgcct cgcctgattc aaaagtagat accaataaaa tgccgattat
    12421 caataataca aaaacactta gtaataaatg ttccttgcta tcaaaatgga tgtatgcaat
    12481 cgcaaataaa gcaatccatc caaaaatacc tccactaagc cccatactta cgatgttgct
    12541 ttgtagcaga aaaggaacta agcttcctag aaatcctgat atgattaaaa cgatcaataa
    12601 tgttaaccac tcatactgat cattcagtgc ttcttcaaga actactaaga acaataaatt
    12661 agaaattaaa tggtacaagt taatatgaga aacgatagaa atgaatatat tcgggaacaa
    12721 atgtccttca tacaaaccac ctaaagcaac catttccttt gcactcaatg tatttccaat
    12781 tatacttttt ccaatctgta aaaaatcaaa caggaaaatc aatacacaaa caaaaactac
    12841 agtcgctact aagtatcgac tactattttt gtttttttct ctcattcgct acttcctttg
    12901 ctttagtaac tgccgattct ccatattctc taaaaagagt cgacgttagc tttcctctcg
    12961 gaatattgta tttttttaaa atttcagttg ttgaaagatt tttttcaaag tcttcaataa
    13021 tttgtttatg aagatttatt ttagccaaat cattggttgt caaaacaggt tctttagctt
    13081 gaatatcgcc ttgacgaatt aacctttgaa ttttattttt gctttttaaa aaaggatatt
    13141 tttcaattaa agggtcaatt gcattccctt catcaatcca cttccctatt tcttgataaa
    13201 ctctcttttg aaattttttc ctcagctcaa tcgggttcgg aaaaacattg tgcttaaagt
    13261 cgtgtgatac taggcttttt gatttgccta attcatcagc gacctcttgc atcgttattt
    13321 tgttttcgat atagcgttgg acaagagcat tatatttttt gaggttatta tcatttattg
    13381 tcatgttctt acctacgttc attgttaatt ttttggtatt tttctgtttg tgtattgtga
    13441 tttttaaaag gtatttccta aaacgttaaa ttttgataat cggttaaatt ttactatttt
    13501 atcaatttct gcctgtgacc acggctctat tgaacacatt tggtacgtca ctagcatatc
    13561 aacatattca gattatctag tggtatatat tactatacaa acaaaatcgt gatagctaca
    13621 atctcgtcct tcttataagc tgaccaacct tcactatcct caacgattaa ctccccatct
    13681 aaagacatat tttgccatct atcaattatt tcttgactac taagtttcag cgaatctatt
    13741 tcatgaaaaa atgactctcc actagataaa taaatactca ttatttcttt tttgtctatt
    13801 tcttcctgct ctttgatcgc ttgttcagtt acttcctctt ctgggtctac ttctagacct
    13861 gatttaacag tctcttgatt atggttagat attatttgtt tttttattgt tgaaaaattt
    13921 tcacaagtta atataactaa cgcaactgtc agaacgaata aaatccaact cattatttgt
    13981 agtcctgcct ttaaatcttc tagataacca atttctccta gataaacaat cgcgtttttt
    14041 aactgattta ttatccgaca aatagtaaac ccagatactg ctatgcaaag atacattcct
    14101 gcaataagcc acagtattct tcttttattc atttagctta tcctccgttg aaaagacact
    14161 ttaagagtat gtgtacccca tcgcatattc ggatcataat ttttcatttg ctgtatcctc
    14221 ctcataatca gttaatacta tatatgaata gatataatat tccttactca tcattccggt
    14281 atctctacta tctcccaaaa tggttttact ttatataatt tcttaacttc acgattcatc
    14341 gatctaacca tgctttctaa tacagttgat cttgtaccta gcgaaacttt ttgtttcctt
    14401 gctttcttaa cacttatcat gctaggatat ttttcattaa acacgtatac gccttgttta
    14461 taatatttac gcatgagtgt gtcgtcttgt agcattttct cccacaaatc actagtaacg
    14521 actaaatagt tataatcgcc gataaatgtc tgtttcgcct tgcttttcaa atcggataaa
    14581 gtaactttga tctcataaca tcgaactgtg ttatctactg aataagttat ataatctact
    14641 ctttctctgc catcccaacc gatagttact tcaaaacaac caaatacacc catgcgattt
    14701 gtttcatgcc ataaacactt ctcagcttgt ctagtaaggt ctgttttcac tttttttcac
    14761 cttctaaaac tttgaatgta ctttttcgtt catcttttaa tgcttcatta atttcttctt
    14821 tactccacgg aacgatcaat cgaacagaat attcgacaac caaatcaaca aattcatagc
    14881 gaaaactatt gatagacact acttcatatg ctatcccttt ctcaggaaag acaatatctc
    14941 ctatttttat tattcgctta tcatcttttg attggtcgta tcgattatcc acaataactt
    15001 ctcttttgca gttataataa tcactcaagt ctccgacttt ctgaactaga actctaactg
    15061 ttaaactaat agatttgcta aaataatgtt tgttaatttt aagaatgcga ataataatat
    15121 acttatcacc tctatattca atggattcac caatacttac tttttcgtta aatccctctc
    15181 tatatagttt tagaatagtt aacacaattt tcacctctac tgccaaacaa atttagcttt
    15241 atcatgccat gtttcagaca ttactttttt accattttcg tcaaatatca ccgcttccca
    15301 ctttgctgtt ccgtccggct gtttacaaat atctgcaaac cataggattg tttttcgttc
    15361 gttgaatttt cttactttct tctcaaattt attgatctga actctatttt gattgctgtt
    15421 ccaacctact aataggcgat tatctgattc tgtaccatga aaaccgatgg gaacgatgtg
    15481 ggttctatca aatgcttctt ttccttctgg atagagcatt ggtctaagtt tcctacgttt
    15541 caagtcatct cttgcttgat accgccatgc cgattttgga ttgaatttaa tagctatttg
    15601 atgcttgctt ttgtcatgat aaaaatatgc cacatctgct tcagcgccaa gcaacttttc
    15661 tcttgcacta tttgattcaa acggtttatt cacttctaaa accttcacac ccaaaattcc
    15721 atgatcaagc atctgtttag gagttaacac cgctttttta tcttttttct tagctcgttt
    15781 cacaactact tcatctgtat atttatatgg cgtaagccac ctcaaaaaag aactgacaat
    15841 gatcatttat gcacctgttt tttggctttt aacatttttt gcatgatagg tgaagtagtt
    15901 ccgtttactt gtttcttctc agaattatcg gttgtgatgg tcacttttac tgaaactttc
    15961 ggatcagtag ttttcggttt agttttagat gaaatcggct gttcattatt cgtgttgttt
    16021 gaggtttgcg gttcaggatc aactttatct aatgctttta aaactttttc taatttttcg
    16081 gcttgaagtt tttctagtgt tttagctcct tgtttttctt tttcttcttt gtttttttca
    16141 agttttagag caaacgtact cttcttttca attgatggct ctttagatga tgaatttgct
    16201 aaaggtgtgt tcaaatttct tttagcagat tttcttacag gagctttacc aattccacca
    16261 aaatcctcgt cttcaccgcc ctcaccacga gattcagcta cgattgctcg gtaatcaaca
    16321 tattctggtt ctggcatagt atttctaagg tgatcaaaga tcgcttcaat ttcctcgttg
    16381 ctgatatagg ctccttgcgc tctgattttg tttcctccat tcaacttgat aaacatatct
    16441 ccctttggac ttaggctttc tccaccaccc tcatctaata cgatcctact ttctaaatca
    16501 cttgctacca tcaagcagac tctagatggg aaatttgctt taataatacc tgtcacgact
    16561 gtagatcgag gtgattgtgt tgcaagaata acgtgaattc ctgccgccct tgccatttgt
    16621 cctaattgaa cgatcagccc ttcaacttct ttgtgtgttc caactaattg cgaatattca
    16681 tcaaccaata agatcacata gggaaatttc tctattccat gtttttcagc gtatttgtta
    16741 tattgtgtga tattttgaac gcctgctttt tccatcaatt tgtagcgttc attcattaag
    16801 atcacaaggt attcaaaaaa ttcataagct tcatccatat cagtaattgg atcagcaagc
    16861 atatagggta attttttata acgcccaaac tctactcgtt ttgggtctac tatccctagc
    16921 tttaattcat caggcattgc atgacagata gctgtaacaa gaatttcatt cagtaatacc
    16981 gatttccctg atcctgttgt tccggcaact aacatgtgtg gcgtatcgct gatgcaaaaa
    17041 tgagcaattg tgccatcagg cttaattcca aaaatagcat ctgtcgggtc tttagccttt
    17101 gtgttcaaca tattgacact gaattttcca ttaagcttta tattaggttc tttatctagc
    17161 aaaatagatt cagctttttc ggctctattt ttgactttct ctaacaattt catagccatt
    17221 tctattcctc tcttttctcg gtacttttct gtttgtgaac tggtagtttg tattttctgt
    17281 ttctatttgt gatgtcttct aaaacacgct attgatcatt gatggtacat caattggaat
    17341 acgatcattt tctcctaatg gtaaagtaat ttgaatacgc cctgcgttga tccgcacgat
    17401 tacacctgat atatgcaagt aagtttcaat ttcttctttc attgagctta gttgaatttt
    17461 tctggtacga gataaagtaa acaaatattc aatagatgta ttcccaacgt gcatatctgt
    17521 tagacttgca ggtacgtcag cagaagatag ataaagttct aaagattgct tttgagtttc
    17581 ggcatatttt ctagcttttt cggtttggtt ttggatattt ttggagttat ctgcaaagag
    17641 attgattgga aaagcaaatt gtgaatttga aactgcaatg gatgctgttg atttttccgt
    17701 ttccttgttt ttggtactta ctctttcctt acgttctctt tcaatgttta ctgatgctct
    17761 gaagatgaag taatcacctg aaacttcgtc ttctttttcc ccaaatttag ctcgccctct
    17821 tgttgctctt gtcaggatcg accctaaatc ttgaatttgt cgtaaaactg tttctctaac
    17881 tttcttccct tttggttgcg gtatttttac gatatattct cgaatatctt cattgacact
    17941 tagatcacgt cttgtatgaa cagaaatttt gatattttta agcgttgata gcacatcgga
    18001 ttctaattgc gttttgtttc gttttctttt tttgttgttc gtttcatctc ctataatctt
    18061 gtttggatca tacttcacat ccatagcttc tagagcttct cttttcaacc ttctactttc
    18121 catatcatca aagaatggtc tttgttctcc atagtgatgc ctgaacatca aagtaaccaa
    18181 atatccgaca aagaataccg ttcctgcttc taatactaaa atagagatat ctaccaagtg
    18241 tagctttgca aaaaagcttt gtacattata tgaataactt aaataatttg gaaaaaacgc
    18301 attgagtaac tctttaaaca tctcttttaa tcctaaatca tctgttccgt taacatcatt
    18361 taacgagacg agaatactta ctaaggtatc tacaagcagt tgtacaacct ttgttaccca
    18421 atgcaaaata tatatgccaa ttgcactaac taccaatgca cgtccaacca gatatactga
    18481 tttagaaaaa ttggctacag gataatattt ttctccatcg cttcgcttat attcctttaa
    18541 ttcaatggat ttttcgctca tctgaatatc tccttatttt ctttctgatt ttggttaatc
    18601 gtcacttatg ctgtcctcac acatctgcgt atctttagga atgattactc tgatttcgtc
    18661 taacatttct ctctcaatga tcatcgcccc ttttgtacta acagttttct ctgataattc
    18721 aacacatttc cctatttcag aatctggatc aaaaatagcc tgttctacgt caaaatgatt
    18781 cttagctaca tacacgatac tcattgtttc taactctcta gcaactgaat atttaccctt
    18841 cttcagaaga tagtagccat ttcctttttt tattcgattt gcaactgatt tatctaatcc
    18901 attgatgctt attgtttcca attcttcacc ttctcaattt ctaatctctt acccaagtac
    18961 cattttgata gttgatgttg attccttttt gattgttaaa tacataaaca ttaaggttta
    19021 ccgtttttcc attatcgtta actgaaaaag cttcgacatg agaaccacga ggaaccaatt
    19081 cattcccttt ataaattgga tcaactttat acaatacttt ttcattctta tttttataga
    19141 ttgcatcacg tacaatcgtt tctgagtaag ccatccctcc attctgatca tttttcccaa
    19201 cattttgcgc tctcgttcca agtgttaaat tgtgtacctc catatctcct cctagcgacc
    19261 atgctaatga atgacttttg ttatagagat aacctttata gccttctagc tgagtgattt
    19321 cattgtttga atctttgccg acccaagtat ctctctcttg atcaaatact ccatccttgt
    19381 attctcctgc aatatggaca gaacttttga aagatggacg ttccacattt ttagatgagt
    19441 gagaatttac agcatcatag gtgatcaacg cttcaacatt tcctgctctt ccaagttgat
    19501 ctaaatctgc ataatttacc caaaaggttt gactgccttt ttctgataat gcttcatggt
    19561 cttcttttgt cagtgtatat ttcccatcat taatgtttac gatattattt ggatatttgt
    19621 ttggatcata acgtatccct aaaaattctt ttgattcact gtctgcttta ttacctacct
    19681 gaacactact tttgatctga aaatcatgtt cctgagtgct gttattctga aagtaaccct
    19741 tgccactaag accaaccgca actaaaacca aaattcctaa caacgatcga ctaaacttct
    19801 tctttttcat accatcattc cttttattgt gttatcataa taagataaat atataataaa
    19861 ctatattgta aattttgtca aatgtatttt tatttgttcc cactataaac cttgatatat
    19921 agccaattta aaaaaggatg acaaaaaatt atcaagttaa aaaaataaat tttgaaccaa
    19981 attattttta ataaaatagc tagttttttt atcaaaaaaa tagagctttt cagctctatt
    20041 ttattcaata tcattttgat caattaataa tcgtacactc caattaaccg agttttgatc
    20101 actcaaatat ttataatctt tgtcatcaaa aaccagttgc caaactctgg tacgaacagt
    20161 ttcttcgtcc acttcctcat ctgaagagta ttgcgataat gcttcttcaa ctatatactt
    20221 tacaacttcc tcaaaatcag taggaacttt atcaataacc acttcatagt cttcttgttt
    20281 tacgatattg ggatcaatat gttcatccaa acatacctca gtgagttttt ctttcacctc
    20341 tgtatctctt tctgttttta ggtactctgc atagtcttcc ttagaccatt gtttttcaag
    20401 atcatccgct atacttttaa taaaggattc tttatttaac caattttctg cggtatctat
    20461 accttcaaac tcaaaagctg ttccttctat acgtgatttg acgaaagcat caattttctt
    20521 gtattgatta ttcatttccc atgaaacaca ctcatcttct tgcgtaatat cataaatttt
    20581 ttcggaaaaa ctaactaatt cattccacga tttatcctcg gcaaattgac ttagtttcga
    20641 agcgataaaa ggaaattttg cttttaagtc atccatattc ttgatctcaa attcgatatt
    20701 ttcttctcct acagctgaaa tccatgctga aagattgatt gcaatatcgc taaagtcttc
    20761 tacattttcg acatttcctg tattatcttt tattactgct tctaaagcca tatcggttgt
    20821 tgcactcatg gtttgatctc ctctcataat agagcaaaaa gccggcttaa ccgacttttt
    20881 gcatggtacg ttttgtttgg tagttttctg cttgtgttta tgttgaaata atccctatag
    20941 ctcttctttt aatagttctt caactttatc tcttaactct ccctgaccac tctctaatag
    21001 atttaaatag ctcatcagaa tatccgtttc atacgttttt aattcagctc tatactcact
    21061 ttctgaatat gatcgtaaat acccatcatt gctaaatgca actagatcat cttgaaagtt
    21121 ccattctcct aaatttgttt tactcactgc ttcccatgga ctattactaa acatttcatt
    21181 aaagaaatct tcgtcatttt gatatacctt caattcagga aaatagttgc tgtcttcatt
    21241 gatttcttgc accatttttc caagttcttc ttcagataat ttaccttcca ataattttac
    21301 tttttctctg tcatttgcat aagccatttg aacctctcct ttttcttttt caatttcttc
    21361 aggtgtttgt tttggcgtaa ctttcaaatc tattccattg cctattagac ctattagata
    21421 accatagaac gttttaaagt cacttgtagc aagagatttg gcatcagggt atgtatcccc
    21481 tccaatttta tctaaaacaa aatcagcaat cgttacccaa ggagaatata tcgtacacac
    21541 tacatcccat gtagcatctt caatattcgt ccatgtcgga aagtcatttt cattcaaata
    21601 gtcttttttc attgtttcga tcagagtttt tccactttcg ttttggctta gatattcaac
    21661 aaattctgca ctatcaaacc tgctactaaa tagtttagct aatgagtcta aagctgtttt
    21721 tgatattccc accattacta cacctcctat taatatttta cgatgacttg tttttcattc
    21781 acaaataaga ttttctacat cttatctatt tctttatagc ttttccatac attatttcta
    21841 aatacaacca ataaccctat taaattaagc ttttgagttt atcttttcta ataatattct
    21901 gataaatatt ctgataaaaa aatttgttgt atttttttct tgactttttc tttagaatta
    21961 agatcagttt tgattttatt taaaagtgaa tctagctcta ttcaaaataa aaaagagatc
    22021 aataatagta tcaatccctt tttactgtac tctatcaatt tttataatct tcattatgct
    22081 tttcgaaact ctttgattaa aagaataaga acatttagac ttgctaatgc tcctattaca
    22141 gtccaaatga ctaaaagcat tttctgatgt ttattggtaa ttcctgtgaa tattgaactt
    22201 gccttttcag caaatgttct gtcttgcatc tctacgctac cttgttccgg aatattaaga
    22261 tcattatttc catctaattc cttgttggca cgatcaacat cctcaaataa atcattagaa
    22321 gatgtaacag tttctgtctt atctgaaacg tactcgctat caatggcatc agcgtatgcg
    22381 gtattgccaa ctgttacttg tggcgtgatg tattttgctt tttcatctct tagacttcta
    22441 actaataaac gatcgtagtt ctgaggatat ggatgacaag tataaagtgt taacatatct
    22501 aaatcaggaa tatcagtcag tgttgaattc tgaccgtaat ttctaataac gtctgttcgg
    22561 aaaaccgtat aaactgcttt ttcaccaaga taatctatat aaatgtggtc tccggctact
    22621 aattgatcaa cataaagaaa ttgtggtgac gtataaccgc cacgatgacc tgctattact
    22681 gtttgatgac ctttacctga taaaggtaga ctagtagcac tcatctgtgc cacacctcta
    22741 tataaatgtt cctgtgaagc gcctagaaac aaaagctcta gcacatttat ttttggaata
    22801 tagacataac caaccgcccc tgaataggta gatggttcaa aatctttcgt ttgatttttt
    22861 gaaaaaacat ctcctgtgta aggattgacc tttccttcag cttcaccaat atcaaatgat
    22921 ccgccgtctg ttttctgagt attgtctaat ccttggttac cgctgttcga ttttatttgt
    22981 tcgacttttt ttgccacttc ctcttttgaa ggagtttgtt ttttctcaat tttctcttgg
    23041 atttccgcca cattctcttt tgttttgaat tgatgataga gctgatttgc aggataaatt
    23101 gttaaaacca aagtgcaaat aagagtcaaa aaaagtagta ttttattctt catttttcat
    23161 tcctcgtctc tttgctacta tttttttaat aatgactatc acagctatta ttaataaaac
    23221 ccctacaact acgataggat accagttcat ctgcgccttt acctttaaat cttctttctt
    23281 cttttctttc tcaacaatac ttttttggta aggtatgcta acccctctaa cgagtaacct
    23341 atgagaatta tctccaacag gtgtacatgt cataagtgtt acataatctt ttcctgccac
    23401 aggaagcaaa tcctcaaatt cggttggtag gattattttt atccgatcta cttgataagc
    23461 aagctttttc cctgaaatat caataaaaaa tttatcacca agtttgagca actctaaatc
    23521 tgtaaaatat tttttattag gaatgcccga atgagctgat ataacagaat ggtttccaat
    23581 cccaccagtt ggataatcag ttccggttaa tattcctgct cctgctgata gttgaaaatc
    23641 gtttacacca tcataaattg gcaaatccac attaatcttt ggtataagaa tttcacccac
    23701 taattcacct aatttatcct tctgaagatt tccatttgac ggaatattgt tattatcttc
    23761 aggaatcgtg actgaggttt gttctgtgtc ttttcgtttc ctattaactt ctgaatatct
    23821 cttgaagact tcttcattct ccttttcaga agcttcatca tatttttcct tataggagtt
    23881 tagtgtttgt tgagtttggt agtaggtata agcctgagta attacaggat atagacctac
    23941 tcctaaacat agcaacatcc caatttttaa gatgatcaac ttgatattct tctttttcat
    24001 gctcatacct acttttcaca cactttttaa aaagaaaccc tagagccaaa aacactctag
    24061 ggaattttat ttcattaagc tttgtgttgt tctcgtttgt agacaacata tagccctgtt
    24121 cctgccacac ctgcaaccac tagaaatact actgttccaa ttccacctgt acgaactgtt
    24181 tcaggtgttt taaggttctt gatgtctgtt acttcgctag aagcatcatc attcgatacc
    24241 acaaatggaa catcatttct agttggtgta tatcctgaag gagcaacaac ttcttcaaga
    24301 gcataatcat tgattttttt atctgtgatt gttggattac cttgtttatc aaaatctaca
    24361 tcataggtat attgcaagcc ttcaatttgg aacttaccgt ctgatccgga aacgaattca
    24421 gtagctttag atttatctgc aatccaagta acagctttcg ttgttggatc ttgttttagg
    24481 taagtaactt tattcggatc aattttgttc ttcactacaa attttgctcc actcaatgct
    24541 ttgcttgtat ctccatctgt tttaatgaat tggtgatcac caatgattgt ataagcgtga
    24601 tcaactggtg tttcgtcttc gggttcatat ccattgttgt agatcgttga aacatcattc
    24661 ttaagtggtg tatccatttt agctttacta ttagtatgag cgttcatcaa aattgtaaag
    24721 aagcgatccc ctgcatcaaa ttgtttctga agcttatcca tacctgattc agtaaagaca
    24781 tagtttgtcg tttgtccgtc acgttcgata ctgtaatcag tatctaaagt cattccttcg
    24841 atcacttctg atgaatcata agttaactct gcacctagaa catctttgac aacatatttt
    24901 tcgtaattac caatattacc aggaattgat ggtttcaatg tatattgaac atcttcgcca
    24961 gtatcaacgg tttctttatc aattacctta gtaattacag gtcgtttgta gttggtaaca
    25021 tcaagaacta ctttagcagt ctccccacgt ttaacgctaa atttgaattt tttaccatct
    25081 agtaaatagg ttgttttatt agcatctgtt cccaagtcgg tttctaggaa ataatagtca
    25141 cctaattcca aaccatctac agttaattta cctgtgctgt ctgttttata agttccaaca
    25201 acctgatcag atccatcatc ttttcgcaat tcaaaaacag ttccggcaag agcctttcca
    25261 tcttcgtctt ttttatcaag ctctgctgag tttaattgga aatagttttt aggatagaca
    25321 tgtacatcat aattaaagta ttgatcatct gatccgttta gttcaggtac gttaacaatc
    25381 ataggatacg cttcttcaac tacacctttg actgttcctg tttcaacaat caaatacaag
    25441 ttatctgtta aatcgtctgt atttacttgt ataggtatgt ctatattccc ttgtgaatca
    25501 gtcttcattc tacttacttc actgtatttt ttgtttagta ataatcgtgc tttagcatca
    25561 tcaatatgtt gaccttttgt agtatcacta tccgtccatc ccaaggattt agcttcatct
    25621 ttagtaagtt tcacataaga gaactcaacg ccttcaagag gttttacacc atttggtaaa
    25681 gctatttctt tccctttgtt atcaatatct gagacagggt tcccatcccc attagtattt
    25741 gttactttat ggatatgaat cgttccagtt ccttgataat tatagttttg ttgtgcatat
    25801 gctacttgcc cccctagtcc aaggctagaa gagattgagc ttgcgcccaa tcccactcct
    25861 agcaaagtac caaatagcat taaatttgaa aaaatttttt ttgatttcat acgtcagcct
    25921 tcttttttca tatttacttc ttttccatta acactttttt attttgcttt gtgctgttct
    25981 cgataataca gtagcaccat actcaatcct gcaattagaa atacaagaag gaaggctgat
    26041 gtaccgattc cgcctgttct tactgtttca ggtacaaggt gattaattac tgtatattca
    26101 aaggtttgtt catcgtcagc aacggtgatg ccttctttag accatttccc tgtataacca
    26161 ttagggtttt gtgtttcttc gattttgtac gttttgttgg caacaatatt aaatgttgcc
    26221 aagccattgc tgtccgtttt ttgtacaact tttacacctt tgtcgtctgt caaagtgaat
    26281 tctgcgtttg ctaatgcttt cccttgatca tccactttat gaactttgat cacacctttt
    26341 ttcaaagtgt ttttagcagt atattcaaag acttgtccat catctttgac ggtaattcct
    26401 tcttgtttga atgcgcctgt gtaacctgtt ggtacttttg tttcttctaa gttgtaagtt
    26461 ttgttcgcaa taatgttgaa cgtagccaga ccagttgcat ccgtcttttt aacttctttt
    26521 acaccttttt catccgttaa ggtgaattct gcatctgcta aaggttttcc atcttgatcg
    26581 actttatgaa cttttactac accttttttc aaattatttg tagctgtata ttcaaaagtt
    26641 tgcccatcgt ctttaacggt gataccctct tgcttaaatg cacctgtgta acctactggt
    26701 actccagttt cttctaggct atacgtcttg tttgctacaa tattgaagct tgcaagtcca
    26761 ttttcatctg ttttttctac ttgtgttgca cctttttcat cggttaaagt gaactctgca
    26821 tttgccaaag gttttccatc ttgatcgact ttatgaactt ttactaaacc ttttttcaaa
    26881 gtgtttgtag ctgtatattc aaaagtttgt ccatcatctt taacggtaat tccttcttgc
    26941 ttgaatacgc ctgtataacc agttggtact ccggtctctt caaggctgta ggtcttgttt
    27001 gctacaatat cgaagcttgc aagtccgttt tcatctgttt tttctgcttg tgtttgggat
    27061 gaatcatccg tcaaggtaaa ttcagcatta gctaatggtt ttccatcttg gtcaaccttt
    27121 ttaactttta ctttaccttt tttaattgtg ttcgtagcag tgtaactaaa ttcttgtcca
    27181 tcggtattaa cagtaatacc atccttttta aatgaacctt gataaccttc aggaactttt
    27241 gtttcttcta agctgtatgt taagccttgt tgcaaatcaa acgtagctaa cccatcatct
    27301 ccggttgtct taacagattt agcattgtta ttgtcagtta gagtaaactc cgctcctttt
    27361 aaagcatttc catcttgatc aactttctta actgttacct gaccaacagc tcttgtccat
    27421 ttagcactca aagatttaga gtcctttgtt tctgaagtag tgatcataac tacggcatct
    27481 tgatacacac ctcgtccatc aaaagtaaaa ggattggttg tgctaacatt agcagtacct
    27541 ttaaatgaca aagtaccact tggtgtagtc acaggtactt taatagtaaa acttgaattt
    27601 aatttcacag tgttgttagt aatttcttta ccatctgcat cataaatctt cataccagct
    27661 ggttttgctg atgtaaaagt gagcttcgca ttaccagtct tatttgatgc tgttttatat
    27721 gtgaaagtgt gatattttcc ttcgtcagct gtcttagaag ctgtgataga aaactcagtg
    27781 ttgggcgtat cttttccatt cttagcatag tcataaattt tttcaaatgc tttttttaca
    27841 cgagctgttt ctgcggcggt atggtttgga tgtgaccata caatctgtga aactttaaag
    27901 tttccggcta aaacccatga aactaattgt gttgcatacc atgcttctgt atcatttcct
    27961 gcacccagtt cctttgctgt ttttgatgga aaaccacctt taaacatacg atagaactca
    28021 tcactgccag ctcccttgta cttcaagctt ccggctccac ttcctgttgg ggatggcaat
    28081 tctgaatcca tacaatatcc aatatttcca tgagaatctt taaattgact tgaaatcatc
    28141 cattcatttg gatgattcgg catattaacc ctaatataac cgtctgtttt tacgccagtt
    28201 tctgtaaatt ttgcacttgt cggttttgtg acatctgctt cagctcttat tgctgaaaaa
    28261 ggcattataa gcgtagataa caccattact aaagtcgcaa aacaataaat tatttttgat
    28321 tttaaaatta tcgttttttc atgcttcatc tctcgttact ccttctttat accagttagg
    28381 cgaagaaaat gagccacgat atgtcggtgt ggtaatgacc ttcgcgccca ttcctaagtt
    28441 aaaatcacca cacctattaa tcactttttt cgttgaaagc aagctgtttc aacgctctag
    28501 tattcatagc atcacccctt ttagttctac caaccatgag caacaagttt tctaagtagt
    28561 taagcaagga caaataaaga ctatacttaa ctacttagta tataaacgat ctcttttatt
    28621 aacgtaccga aaccgctaat tgagatacgt tatatgctgt ttcaaatgat cctgcattaa
    28681 tccaacttgc cccaaacaca ggatcgacaa catggtaaaa accgtcttta aatccatcaa
    28741 cggctactac atgtcgattc caaatagcat cgccccaaaa cattgattta tgttgagcag
    28801 gttcaaaggc ataagttacc cacgctacta caggatttcc atttacaatc tcatctttta
    28861 atccttgtac cgatgaacca gaaatatcta caacatttcc gccattagca acaccccatg
    28921 aaactacagg agccggattc ataccttgat aagttccatc cacattgtgt ctccattcac
    28981 cagaaaaacc attatttgga ttattatcag gagatagtgg cattgattta acaaaagtca
    29041 ttaaatcttg atttgttgca acacctttat aatgtaacgc ttctagcaaa gatgttcctt
    29101 cgcaaagcat tgtgttacct tgactaataa atggaacgcc tagcacaaca ttagttggtt
    29161 gttcgggttt acttggtgaa gtagaactgt cagtttcatc acttgaacct gtttgtgatt
    29221 gatcactaga agatgtactg gttgattcat ttgcatcatt tgatgttgat tgtgagttat
    29281 ttgttgatgt tccagtatca gcttccgtag tgctactttc acttgttccc tgtgatgctt
    29341 ctttctcact tgtagaatta tttgtattag atgaacttgc tccatcaaca cttgaagcac
    29401 ttgtttctgt cttatcagaa gtgtttgctg ttggttccga ttcttttgta gtctcggatt
    29461 ttttgttctc ttgctccgta ttttcaacag gatcaggttt atctttttga acagtttgac
    29521 taactacttc gccatctgct tccttaactg ttaatgtatc tttattgatg ttgaaagttc
    29581 gtccaatcgg gatagtccgt tgttctcctt ttgccaaatc aacattgttc aattcggcaa
    29641 actcagcaac agtagtcttg taacctaagc ttttaagctt ctctacagtt gaccaaatag
    29701 tatctccttt tttgaacgca taacttgatt gtcctgttgt aatttggatt tgatccggtg
    29761 tgtttgcagt ccattcatca gcatgtgagg ttactggtac tgataacccc gcaagtacag
    29821 ctgatgcaaa taaaaccata gcaagcgaat ttttcttcat attcattcct tctttttgtt
    29881 tttattttct gtttgtgatc gcaatgcttc tattccttct tccgttataa tataggtttt
    29941 gtcacccact ttcttgaacg aacctttagg caaacgattt ggataatagt tgattatgtt
    30001 tgtaacataa tttctacctt tacccaaaat tagacttgct tcccttgcgg tatacaagtt
    30061 gtatttgtct aggttcaatt tctttttatt tgcgatttag acctacccct ttcgcaaaat
    30121 ttattttata ataatagtac cattgcacta tcataattgc aataattttt tggggtttat
    30181 cttcatttaa tagcctaaaa aggcttatta gataaggaat atctaactaa tcaaaacaaa
    30241 aaaggaagtt aagaagaaat gaacaaaaaa aggaaattat cagtattaat tacacttgtt
    30301 tctatgttgg ctattcttag tgggatcttg tcgattaaaa ttttcaatca aataaataca
    30361 agcgcaaata ccaaaaacga aatagtcata gaaaatacat ctaattctaa agaaattagt
    30421 actactaaaa acaaagacaa atctgatgaa accactacta aaaattatct aataaagact
    30481 gtttattttg atgaacggaa aacagcaatt ctcaaagatg aggaaggatc agaattaaag
    30541 ctacctataa cggtatccga taagttcaat ggaacgttct ccttacaaac cgctgaagga
    30601 tcacctgata atctcaaagt tgggcaaaca atcattcttg gtaaagacga agaactgtat
    30661 tcatttgtaa aataaaaaaa tggagcaaag gctagtcaag cccttgctcc attttccatt
    30721 cttcaagagg tgtagctatt tcaacaccaa agtttaaata ctgtggatgc tgtagataca
    30781 tgatattcat tctattttcg ataaactctt ttaacgttga gtaaatatat ttttctaatg
    30841 ctatatctgc ccaactatca taatcaagtc tattggtgat attgacgttt atttcaattt
    30901 gagaaacatc aatattttga acatcaggaa acttattcag tcttagctct tctctaaccg
    30961 cttctactag cggttcatat tgtccgtctt gttcgctaat tgttgaaact atttcatctg
    31021 aattccaacg atcttccaat acctttgcta cattttcttt aggcggttgt ctttctataa
    31081 attcttcagg tgtttcatca aactctactc taaagttcaa tttattttga ttgttagcgt
    31141 acatataatc atctctgttt gattcaaaaa agttacgaat tcctgtatct gatttatcac
    31201 ttaactcctt atttgctaag ttagcccaaa aatcccaagt tcctctattt tcagtataca
    31261 aagtaaaatt aatgtttata taatttgcag tttcaggata cccttgctct ctaagagcat
    31321 ctttaacaat caccgctaag tcagtttcaa aattctccat aaaaaattca ctaaattctt
    31381 ttggatccca cgtttcttct aataactttt ctaatttacg atctgccatt attattctcc
    31441 cccactttac tttcttatat ctaaaactgc ttaaaattaa gagctataac ttatcataga
    31501 aggtttttta tgatttattt aagtctacaa ttctatattc taattatcat ctagaccatt
    31561 ttcttatgtc aaataaacca tatatattgt ctttaatagt tttatttgac tttttaagaa
    31621 agtatttact tttgactttt tttacgtttt acaacatata cgtattgtaa tgttcagctc
    31681 aatttattat aatcaaaatg aattgattaa taaaaattct gaggttcggg ttttttatca
    31741 attcttttct gtttgtgttt gtgatgaaac aatccttttt cggtaggttt tgttatcatc
    31801 gtcagcacaa agagctaacg ttggtaccgt tagctctttt tttattttac tctgctctta
    31861 catagctatc taaatcctcc aagtaaaaca attgattttc tcctatgctt gttactccac
    31921 gccaaattgt tgttgttgct gttgttggag tatttcttgt ctgtgtaatc aattcaacca
    31981 ttttaccttt ttgatttgtt gtatagtaat cagcagtata gctagatatt ggactattac
    32041 cagtacctac cattgtgcca gagatatcaa caggactaga ctttactatc tgaggaaatt
    32101 ctttttgtat ttccttcata ttcttcgtat atttttccca tgaattccag ttgtaaaata
    32161 aattaaagaa tttcctactt tgttccttga tttcagcatt tcccaattct ttgtattggg
    32221 cttcttgcat agctttcact ttctggttat tcttgactac ttcgatttgt ttacttttaa
    32281 ggtcttccaa ttctttgaca ttattatcat aagcattttt cttttgaaat agtaccacac
    32341 aacaaaggat caaaattatg gaaagtattc cgatcgcctt tttagcagta gtaatttcat
    32401 gattttgcat aaaaagcacc cccagtcact ttcttatcat tatttagtgt gatggttaat
    32461 gtggtatcat acactttttt tccgttgtat tgaacttcga aatcagtcaa tgcttcatac
    32521 aacccactac tagatgtctt aattccaaag tttgttagct taaaagtaaa aggtttatag
    32581 tattctattt tttcttgctc gctactctcg ttagtaactg gtggcttacc tgtcacaata
    32641 aataactttc gcaaaaattc ttcacctgac tgattcgcaa atttgcttcg gtctgatcct
    32701 ttaaacatct cttgaatatc attttctaaa tctctttgca atccatccac ttcatttggt
    32761 ttaacctctt taaagaaggt caattcattt tcaatttgca cactgtgctt ttcagcttct
    32821 atgtcttgat tctgcttatt gaaatataga attccaacaa gcattgctaa tagcatacca
    32881 gaaagcaaag aaatgataat tgcatctttc gttttactat tcatctctgt cgccctccat
    32941 tcaaattttt atttttcaat ttcaaattta gctttgccta caccgctaaa gaaatgcaca
    33001 ttatctgacc catccacacc atcaatcaaa gttactgaaa cacctcttgt tggtgcttgg
    33061 gtaggtggaa cattgaaatt agcgcacaaa aatgatccat cgtcaaacac cgctataact
    33121 acacctgtat gtcctgctga tccaacagcc cataaccatc catctaaagc actaaacgca
    33181 taacctacaa ttggtttgtt cgtcaccttt gctcctgccg atttgtagct ttcccaaacg
    33241 taaccgccat ttcccaaagt tggttgattt ccatcatata attgactcat ataagcccat
    33301 gttaattcag tacattgtcc ttgtaattca ccttgaaaag gtgatgttga ccagtctggt
    33361 tctttaaatt ttggtagcgt gattgctttc ccatattttt ttaatgcttc ttcataagtc
    33421 atatttgcta ttacttgacc ttttttaccg ttaatttttc cttctttccc aattgatcca
    33481 gaaccagaat tagcatcatc cgtagttgca caggcatctt ctactgttcc tgatgctgaa
    33541 cttgatgaat tattcgatcc atctccggta cttgaacctc cggatatttt attgatctta
    33601 ctttcatctt ttgcaccgtc catacccttg cttttcatgt acttccagat ttcttttgca
    33661 ttttcaccac gtacagctat tacagctgat tcggaatcag ctgaaatttc ccagttttta
    33721 tgaaaagtta ctgcattttc tactacatca tcagaagcat ttaaagcata atcttttaat
    33781 attcctacga atcccccatc acctttgaac ataaagtcca attgggcttc tgtagtccac
    33841 caagaaccgc cattattttt cttagaccaa tcaactaatg ctgtatgtcg cccggctgtc
    33901 cattgaccat agccaatacc cattagacca tcagtaaatt gtttgatgaa gtcaacttct
    33961 ctctgcccat cgccgtaata cccttctact gttcgaggat caatacctga ttcttgtttc
    34021 cagttaccta aaatacctgc aatactagca cctgataagc catattctcc attcatgtat
    34081 ttgtaaatat cttcaatatt tttggctaca tcacctgtta cagcgccact tccagtatcg
    34141 tttccatcgc tatctgttcc tgacccacta ccttcagtag tacagttaaa ttgtgcatca
    34201 taagtagcta tcccatcagc atgtaacact tgcggattta ttgtgattac actcattgca
    34261 atccctgtaa actgcaccat taacgtaagc aacgtggcaa tctttctctt agattttttc
    34321 aataactacg cccccaaaaa gtgtactttt ttatgttatt atgataatat aataacataa
    34381 attaatagaa aggaaaagct aataaatgac tgataaaaca agtgatttac ctaaactaga
    34441 tccaaaaata tctcaagtta agagcaaaaa agatggaaaa actaaaaatg ctgtaaagga
    34501 aacatcctcg ttactacttg atattccaat gagttctttt gatgaaatac ttgatgccaa
    34561 tacggatgaa acttctgtta aaattgcatc tcacgttgga atgaacagtc aaaatgatta
    34621 tttttacaac ttgttaaaca gcctaagaaa gttggaagat aaaaaaaatc aggtaatcgc
    34681 ttcaaaagct cctgacctca caaccgattt ggatgctgaa attatccaaa tcaaacaaga
    34741 tgagcgatca gttaaatcgc tactgaaaac ctactttgat ggttttgata aagaactagc
    34801 tccttatagc caagcaatcc taactaaacc aatacaagct ccacatattt caatttccct
    34861 acaaaaaaag agtgatgact aaacagtcat tactcttttt tagatttctg gtaagcgctg
    34921 atcgcaaaaa ccatcaacaa tattgactca aaaaatatgt tcattctttt ctcttttttc
    34981 cattatagat ttccctctat tccgttaaat tgaaagtcac accgattact acaaagatta
    35041 acatgaccac attcaaaaac attaaaagat atgctgataa tctcatcatt tttttagttc
    35101 acttactggt aatctaaacc tttgagtgat tgcactggaa ataccatatt caccaattac
    35161 aagcaaaaaa tacgcaataa tttcagttcc acctagatag atcagtaaaa taagtaagtc
    35221 acttaacatt gttagtttcc tcccagtata tgattttcat ttttgggaag tcttttataa
    35281 tccaattcct caaaaaaagg aaccatagtg tcactaatat aggttttagt ttcaggtact
    35341 gccaaaattc cccaatcaag aatttcttcc catgatacat catcaaattc taaaatatta
    35401 tgatcaactg acctattacc aagttcatat ccaccaaaaa ttaccatatt atcaatcatg
    35461 tatagaattt catccggcga accatgagtt aatgtttcgt cctcttcaag cagttcgttt
    35521 aatctttgtt tgtattcttc tcttttcata cttttatccc ttcttactca tttttttgaa
    35581 ttttaacatt tttaatccaa gtctgcttgg tatctctgta gtagtcatgc gcttttattg
    35641 tcgccttaac ttttcttatt tctccaacat cccattcatc ataataaaga aatttatttg
    35701 tcttccaaat caatgaatta tggttttgat cttcaaataa atgcaggtaa acattgcccc
    35761 attgtgtatc tatggtgacg gtattggtaa gtttcaaatc caattccaat cgttgagcga
    35821 ttgtaccaat aaactcaccc tcttctctac gcttcgcact taaaatctcc tgttgtcttt
    35881 tgctgtattc ttctagcttc aactcaataa ttccttcatc attgattaca gaaaattctt
    35941 ctacaaaaac tttttgagtt ttgtattgtt cttgtttttc cttaaaaaaa ccaacctaat
    36001 aaaggatcat aagtagctcc ttgatgatgc agttcatctt tgatcgtata gctatttttc
    36061 tctataacca cgtaaatata acccttttca aagccataac gatcaaaatt tttctgagat
    36121 tctttctctc ttgcgatcct tatttttcga tcagctcttt ttttatttaa aacatttagc
    36181 ttagttctat attctggcgt aaaggatttt tcagttacaa caagaaatcc atcaccatcg
    36241 cacttaaaac atgtgccata ggtaattttc cccatagaca taaacttgta ctgacctgat
    36301 ccgctacaac gatagcaagg gatttttttc ttcatgatta tagttccatt tttatccggt
    36361 tgcgatttgc tgatgatttc ttcttgactg aacatcctcc atactccttt ctgagcgagg
    36421 ataaaacctt gctcatcttc aggttgttta aaaactagga tcgtagtatt tttctctatc
    36481 acctatataa aaatgaatat cttctttaag cactttccat ccattttttg tcttaactaa
    36541 ctccaatatt tgaccttcag gatttctgct atattcccac tcttgatctg gaaaagtagc
    36601 tttattgatt gctccatccg cttgaaccaa aattctgttt ttgcttttta cttcaattac
    36661 tgtataagga tttctgtcgg tatatagaag ctcggttgct cccattccaa ctacaatctc
    36721 cttgtttgtt gtactgcctt ccatcattct attttgtaag ctaccttcta atttcattta
    36781 agatcaccct ttctcaactt atctacaaat tcaccataca taccgataca cattttgtaa
    36841 ataaattaat tttataaata gataaaaaac gatgcctatt tagcatcgtt tcatttgtta
    36901 atgtttaatt ataaaatcgg actttaggag aatgatctgg aaaaatagac tctgtttcta
    36961 tttcttggat gagagaaact ctctcttcca tcaattgttt atactttgat gattctataa
    37021 tttcacttct agatttattt aaacacctca tagattcata ataactaaac attctatttc
    37081 tatttctatt ttcatttaac agttccaatc tttcctgatt tcttttctta ataccttcta
    37141 tttctttcaa ataatttatc cccttccata ccaattatga tgccacattg gatgaaataa
    37201 tcacatacta tttttgacca aataactggt caatttagaa ttatttacac caaatatcct
    37261 tcagattttt tactacttca taatattctt gtgagtcttg aacctctttt accgctacaa
    37321 ccgctgtcaa gtctttagga tgaaatctaa gtgccgatgg ttttatcata ctccatcgag
    37381 tattttctaa tcttccctta gtttcaagta aagctacttg aatgatattg tctcttttat
    37441 tgtagtaaaa agtaaacttt tctgggaact taatcattga gtttaactct tcaaaccatt
    37501 cttttgatcc aaattcaact tctaccattt tcctatctcc tttaatttca tttttcgtct
    37561 attgttaatt aattgcattg cgttccttta tactagttag ataatcgttt atttcagcta
    37621 tatttttgtc tgcataccat tttggataaa gcatgtaagc atgactatct ttacatgcta
    37681 ttaattttta tctccatttt gatatttctg cttttttcta ctcaccaatc aaccgtagat
    37741 cctcaacatt ctcaccttca agcgaatatg agtatacttc gccgtaaata ttttctataa
    37801 ctacgacttc ttcttcaaag tctatggact gcacatcaaa ccattctcct ccgccaaatt
    37861 cgtctatgat taatacctgc aatattttat ttactgccat ttcaatttcc ccttatacca
    37921 ttctatgtct tccaaactat ttttcttctt tccataccaa ggtttcacgt atctcaaaat
    37981 tttctttaaa taagtgttcc ggtactttta taattaactc ttttcctact tttatcagat
    38041 agtctttttc acctaatgag atttgaccag tcggtaactg tatcgaaact cttttagttt
    38101 tattaaattt tttagttttc aatacagtat acggtctaca gaatttctct aagcgttcaa
    38161 atcttttact atcgtattgg aaataagctt taggaacaga taaagtacaa aaactatcgg
    38221 taacagcact tatgtctttt ttagaaatta tcccaacttt agaacttcta aggaaagttg
    38281 ctaatttctt atatccacca tgacttgttt caatatagat gctattgtat tggctgtcgt
    38341 ctatctcatt tattgtttca acctttttcc tgacaggtgt ttcaacgagt tctcgaacct
    38401 cttcttcact gtacgctaat acaattaact cttccccatt taccatcttt agaacatacg
    38461 cttgcttctt ttttcttggc ttattttgag attcaacata accagacctg gaatctttat
    38521 acttccaagc atgtactttt ttctctaatt tctgtatctc ttttttcagc tgtagatatt
    38581 cagacatttt ttcattgtaa cgttcgcaat ataaacaata ttcatctttt ccaaaatcat
    38641 gatcaagtcc ttcttcaata tgtttattca acaaactaga aaaatattga ttatattgct
    38701 tttttcgcaa tttaagctct cgtaaatctt tagacatttc atttttcctt tccaattatt
    38761 agtgccgttt cacaatttgt aattgactaa acacaataat taatttgtaa gctaacacca
    38821 attacaactg ttagtaattg ggttagtctc tatcagatta tctggtgaat ttttttatta
    38881 aacaaatttc atagctttca aaaatcgctt tgcttgaaaa ggtgttattc tacaaacctt
    38941 attcgccaac tttcaatctg ataaagcaat ttgccaatga acaatgaact tcttaggaat
    39001 cgttctatta ttaaacaatt agtgaattgc tcaaagttct aatcactccc tctcttttat
    39061 tatacacact aatgtgtata atatcaataa ttttcttttc ttttttaata gaatatgtaa
    39121 tctatcaaat attgatacaa catttgtaac gatgctgttc gtgatcaaat tgttagcaat
    39181 actcatttca acaaggaaat atcgttctta gaaaaattct gcacttctta attatgaagc
    39241 agtcatattt tattattatt aaaattgttt agctatttaa ttgactagtg gctaaaatta
    39301 tagagaccaa gtatttactt ggtctcacat tctcttatat cattggttaa ttaactacct
    39361 tcctttcaaa atatcaagaa ttttttttgc tttttctttg tcttttgtat agaacaaact
    39421 atgaatgttt ccatcaattc cttcaaagtg aacagcagat tcttcatttt ttcgaaacca
    39481 ttctgtcgat gagcttagca catcatctgt agcaactctc ctataattcg tgtccataat
    39541 tccatctttt acttttgtaa ggtatatatc cccactaact tctgcgacta ctaattgtaa
    39601 attttcgtat gccatatttt cttacttctt tcttttttag ttgcttaatt ctactagata
    39661 acattgatta ttcagagact tcaagtaaca catctgacca tgtttcaagt tagttatctc
    39721 tgattttagt gatgaaatat agttcaccta aaaaacaatg ctccgaaaaa agctaattcg
    39781 aactctatat ttttttgcag tgtcatcaat ttttgtcaat tggactatta ccttcttttt
    39841 cttccaaata gttttgtgca agtttcctta cttttttcat catcaaattc gagagttttt
    39901 gattatcttt ttcgctgtaa aataatctac tcgttaaact tttaggataa tctttgatag
    39961 aatatgcatc ccaaacgatt ctttgaacat actcacgatc tatattttct ctgacttccc
    40021 cagtccaaaa atgttgacca taatggcatc tttctattac attgttagca gaaacttcaa
    40081 aataagattg ttccctttgt attatcatgc caaccatcat agcgcaggaa ataactatta
    40141 ataacaagcc tgtttttaat ttattattcc acatgcaaat tccacatcct tctctggata
    40201 aaaatctcct tgacactttt aaattacttt tttaaatata accaccaaaa caagatcatg
    40261 ctgataaatc caagtgtata caagataata aattctttgt taattatcca aaacactctg
    40321 atttctttta gcttttcacg cattagaaaa caccttgtta tatctttttt gtatttcttt
    40381 caattgtttt ttaaaactca taaacaactg ttcatgatct ggtctaagtg ttaaaatatt
    40441 taaattattt atctttgtta attgagtaat aaaatctatt ttagattttc tttcaatatc
    40501 aaatccaaca ataatctttc ctgttggatc aacacatttc acttgaatag ctttgtcatt
    40561 ttgtgatatc tctaatattg atgatttttc ttctgcttct tccaaaagat gttccaacac
    40621 ttcgttaggt gttccatgat agtaataaat catggtcttt tcgaaaattt ttatcggatc
    40681 aacaccatat tcttttccga ttcgataaaa aaatttcatt ggaatttctt ccggatttct
    40741 gttcctgctt gaccaattag agatggtttg ataatttgca aaatggattc gttcggctaa
    40801 cctctgaact gtcgtctcta aatctttttc tattaattgt tttacagcac caatgttttg
    40861 tgacatttac tttctatccc ttcaaattcg ttgcattatc aattctaaga tttcatgttt
    40921 taacgcatgt ctgtctacat tttgcttttt taactctgca ctataatatc ttcgaatccc
    40981 tttatccaag catataattc cttgatctaa tagttcatat tccgcttttt caagtcttct
    41041 ctttgcctga tcaacaagca aaatgatatt gtgatgtgtc tgattaaact gctgatcata
    41101 ttcctctaaa gttttagcat ctaagttagc aatatgatcc tctgctaatt tttgtgttaa
    41161 aaataattcg actttctcag attttaacat ctgtattttt tcatactctt gttttgcttg
    41221 gatatagtca tctttcaagc tagacatgta actcatctcc ttacctgtat aaactgatac
    41281 ggactgtcca aaattgaata gattggtgat gacttcaaga agacttcacc attttcacat
    41341 gaaaataaac caattaattc ttcaatttca tttacgatca gatattcatt agttaaaatt
    41401 ttcccatttt ctttttctag ttcgacaatc gcttgattcc atgtattttg cactaactct
    41461 tgaatcaatt tcaatctatc catttttttc atctcataca gggcaatgtc agcttgttta
    41521 atgcctttta atttgcgaaa ggcatattta tattgtgtgt agtttaaaaa gcctgtgtag
    41581 ttatacatgg gctttcctga tgccttgtat tgaattaagc ttgggtatat ttcagatttc
    41641 cactttttct ctgaaaattc gtcaataatt cttaactgat caggtaaatc aacatcgtag
    41701 tatttttcaa ttattagttc ccgatgaagt agatgtttct ccttttcttt ttggattaca
    41761 aaagaagaat tttcactcag tctacttatt tcttcccttg ttaacccaag tcttattttt
    41821 tctacttcag ttttaagttc acgaatactt tttgccttta accacttccc atttgcaccg
    41881 ttattgtaac cggtaagtaa ctgtatttta taaattcctt caccatgaag caccttatat
    41941 ataccaacct gattcttttg cggaatatga gcttcatttg cactgatttc tttcattacg
    42001 cattctcctt tataatctag ttaattagct tgtgtgtttc gagtagttga gtaagaacgt
    42061 ttgtttcaga aatcatttat ttgttatcac ttaattttaa aaaaataggg cttacgccct
    42121 aaagaactat ttaactttgg attgatcgtc cataacaggt tctgactgtt gatataattt
    42181 atatgctccc aaatccatat aatatttagt tgtactttca atcatttcat cagttgtatt
    42241 tgttgtcatt cccattacat cccagtatag tgtgccatta actttctttg gtgttactac
    42301 tgcaactgtt ggcgtatgat attgattgtt ctcatcagcc agaccaggaa tgttttgtat
    42361 ccactcaggt acaccatcag taatatctac agcaactgcg tgatactcgt aagctggttt
    42421 atttatggta atatcatgca ttaatgttgg agcataacta aatccttctt ttatttcttg
    42481 catgattttt gattctgctt tttgacaatc tggacaatca ggtttgtaaa gaacgatagt
    42541 cagattttta ttttgcaatg gatcattccc ataatcttca tcatttttta ctgtattaat
    42601 aaagtcggta taaacttctt ccggcttttg acctttatta atgtcttcgt atttttgata
    42661 cttttcagca ttattttcag tcattgaaga aattgttgtt gatgccgatg tagagctgtt
    42721 tttagtaacc accgtactac tagactttgt gtctttgtta ttatcagcac tattagttgt
    42781 accacatgct gtaagagtta ttaatgctgc tgttgataac aatacaatct tccatttagt
    42841 tgatttcatt ttattcacct atcctttttt cgtttgttta acactaaaag aataacccgt
    42901 actatccaat aaaacaacag catcaatatg gaaacccaaa ccatttgcac aatccaagca
    42961 taaagactaa ataataggta ttgtggattt ttttgaatga ttgtatttga gatgccattt
    43021 cctacagtaa aatacattgt tacgaaaata acaccttcaa ttatcaagtg atttgttggt
    43081 tgattaataa tttttttcat atttttactc ctaaactaaa tttattcttc ctgctaaata
    43141 ttgaaaatta tatgggttct gcacatattc cctaagttcc ttaatacttg tatcaatatc
    43201 accaaaggct gttttaatgt ttgctgaccc atctttatat acaatcattt ccccttcacc
    43261 catacagaaa gaaatttcag tattagaaat gattgttttt tcagcacgac cattgataat
    43321 ttcttgacca tcacgccata taaaatacat aagataaaat acctcataag cgttgtatcc
    43381 agtatccgtt gttattgata ccaaaacatc agcatcttgt attcctgata aagctaatcc
    43441 aatttcatgg atcacatcaa cttcattttc ttcccaatct ccactttcga agacggtata
    43501 ggtttgattg ttagcaaatg gttttctctc tatatcgaac attcctttcc aatcaagaat
    43561 catgtacccg attaaattgt gaaagaaaat taaataaaat aaatacaata agatgctaac
    43621 tacaaaaata tcagccatta ttgacatagg attatcagga tataaccaga tgtaaaacga
    43681 ttgtttcaaa tccatttttc catcatctcg ctccatatat ttatgctatc atgataacat
    43741 aataacataa atttgtctcg ctttttaata tttttttatg gtaaacttgt catacaaaca
    43801 aaaaaaggag atttatatgt ttatattaga tgatgaaata aaaaaagtta aaaatcctag
    43861 aattattcca ttattagaag aagttcgaag tagtttttat cagggaaatt atcgttctgc
    43921 aatagctgtc aattacagtg cgcttgtttt agatttaatt gataaattat ctgatttagc
    43981 aaatatttac gaggatatta cttctaagaa aattttagaa gatatagcta gattaagaaa
    44041 aagtgatcca aattctccaa aatgggaaat ggaactacta gaaaaagctt atagttcaac
    44101 tgagctaatt gatagctatg aatatgagga tttaaaatat attaaggatc aaagaaatta
    44161 ttcagctcat cctgtagtca cttacaacgg taatacttgg gaattaagag atataacaaa
    44221 agaaacttgt caggatgtta tacggaagtc ctatgaaatt atattcctaa aaaatccaat
    44281 attaggaaaa aaagtaacga tcgaaattat acaatatgca agtcgcatac atgctatgtc
    44341 tgttacccct gaagaatttc actctgcact aaaaaatagc tatctaaata aactaagcga
    44401 aaaagcaaaa gaaaacctat gtaagacagc ctttaagttt gtttttcaat taccttatgg
    44461 aaatgaggaa gcagatagag atagggaaag tactttcaga ctacttaatg ccctaatttt
    44521 tgataataaa gaattctatt taaaaattct aaaagaagaa atttcaaagt ataggttcac
    44581 agctgaatca agagaggaaa ttaataaatc acttggtgaa aatcaacaga tcacatatac
    44641 aaaaggggtc tttttactta cttttatagc tacccatcca gaattacaac atgatttttc
    44701 agacgagaca attcaaaatt tacaaatatc aataaatgat tttaaaccga aacaacaagt
    44761 actaacagaa atagaatatt actaccgttt acgttcactt gcagttctag gaagcaacaa
    44821 tgaagaatta caaaatcact taaatagtct acttgatcct atacttcagc aaaaaatgag
    44881 agtttcttcg ctaccatctt caacattaga aacaatatat aatcaatatt tatattttgg
    44941 tgaaaaagag atgttcatag attttatgat cgaacatctt accgatgcta gttcattcag
    45001 gttagcagat aaggatatgg aagtattacc atggatttac aataaattaa atcaggagca
    45061 atttaacaaa ttactataca acctaaatgg aaataatcaa ttttacaaaa acagtaattt
    45121 tccgcctttt atttctaatc tgttagactt ttataatcag aaattccaag tgaatttacg
    45181 taaacattat agtgggcttc tatatccaaa tgcagtgact atggatcagg gttttcaatt
    45241 aaaggataaa gaattaaaaa acctgtatga attagctgaa tcgaaaagtg atatgtatct
    45301 agacataata gataatatta ttaataagtc tgaagactat ttaagaaaag aaatcaattc
    45361 cgagaaagaa ttgttaaatt atgttcacaa aataaaataa tttcttataa cacaagatgc
    45421 acttttatag cgtatattta ctttcaaatt aaactaatta gttatattct cacaatagca
    45481 tttaataata aatatactgt cgcttgattt atatatttcc ctcttctttc tttagaatct
    45541 ctctttattt tgatataata aaatagaaat cgcaccaaac aatgaaatgg cggaaaacat
    45601 ttcattgaaa aaaggattga acataatgtt caatcctttt ttatagttat aatcaattaa
    45661 cattcggtgt gtgaaattga atcttcgatg ctttcacatg gaaaattatt gattccttct
    45721 tcactcattt cccatgtagt atagaaagga gttaactgtc ctccatactc ctgaataata
    45781 aaatattttc catcattgat atggttacaa cagtacactc caatagttgg atactcgact
    45841 actaaaaatt ggtctggatc aaactgttct tttttcaaca tttctcgtat ttgaaacaaa
    45901 tgatccttct ctaagcaatc aggtaattcc tttattcttt gcgttactaa tgacccctct
    45961 atcgctttcc attcatttaa atattgtttc ataacaattc attcctttta tgttaactat
    46021 ttttcctagg aaattgtttt aaaacgccac tctcccagaa aacgtaagat ttggttagct
    46081 agaatatacc ttccagctaa ccacaatttt ccattactat attgtaagct tgctttcact
    46141 tcataaaaat tgctgatata ctcttttcaa atcgaactct tcctatctga gaagggtatt
    46201 tcttgcgcta gcccctcata agttccatct tcattttccc aaatttctac ctgaaatact
    46261 gaattattgg ctaatttttg ttgcaagaga taatagggtt cttcttcata cttttgatcg
    46321 acttctttaa gacattcaat agcatcaata tcaatatttt gaaagcccaa tttttctaga
    46381 taacaatcgt accaagtacc ccatgtatta tccagaaatg agacaaatgc atgatccata
    46441 tcatttgcta taaaagattc atcttcccac ctgaagaggt aatcccactc accgtttgca
    46501 attttagttc tgatttcatt ttcttttttt aactcaaaag gattacacca acaatgctca
    46561 tgtcgcatcc aaacaaaaaa ttgtccattc tcatctattt taaattggct gagatcacct
    46621 ttcaatctaa atacacggtt cttttctggt aacttattca tgcttcaacc acctcatact
    46681 gttctctcat acctttgact tcattaaaaa aaactctcgc tttttcttca tcagtaaagt
    46741 ttttatacaa ctgattacaa taatgaggtt tttgaagttt ctgaatacct atactaactt
    46801 caaatccttc ttcatgttga attaggatta cttctgtgtc tctacctaga aatattcgat
    46861 ctaaaatttt tatgtttggt ttcattattt aacctccgct ataattattt cactcagtaa
    46921 ggtttcgctt tatgaaattt ctatagttct cttttcacaa aacgtaccat gttctctaag
    46981 actgttttta gtctcaaata tacatgtttt ttcttatcct ttccttatac actcaaaatc
    47041 aaagataaaa cttaaagaat aaactctcca ataacaaaat tattagtcag atccactggt
    47101 ctcctgatct gaaatttatt acttcttcct gttgtcaaat attgtctcaa atcaacagaa
    47161 agtttttgat catcttctcc ttttctagca ggagcaactt ttttttcata cttcattaac
    47221 tctccactgg tcatctttcc aatgatagtg taattaaaat cactttcaaa actttggtaa
    47281 atttttccat ctgtattgaa tatatcagct gtttcaatat cttctttgta ttcattgtct
    47341 tctcctgaac cgattgtatc aaatagaaag gcaagacgaa ttccatcttc ttcaagcatt
    47401 gttaatcttt ttttaattag cccaacggtt tcaatagata acttatcgaa gccgtgaatc
    47461 ataacaatat catctttttt tgcttgtgat gtgatgaaat caaaggtatt taaaaattga
    47521 gcttccataa cattgatttc tgctcttaga tcacctaagt tatagtaaaa ctgtaatttg
    47581 tcacttttac cgatttcttt tagtgtcgtt ctttgattaa acatcctaga gaagctgtct
    47641 aatgctgttc tcaatgtgtc ttttaataca ataatacgat cgacttcttt ttcagtacca
    47701 gattttttgg cttttgtttc agcattagtc aaatagctaa taaaatcccc aagaactggc
    47761 attgtatcac tgctgttcac caaaagtttt gaacgttctt cataattaat atcccaaagt
    47821 ttctgactta tataaaagtt acctaattct tttttcaata aaactctagt tgcagaatct
    47881 aatgttctgc ctgctaacaa ataaaaaatc tgagttagtt tatcgagatt ccgtctatat
    47941 aaatcaccaa tgtccttttg attaccaaaa agctccaaag agttaagacc ttcttcagcc
    48001 aaattaacct tttctattac actgtttaac gaaggtttgg caacaaatgt tctaccagtt
    48061 ggatcaccaa agtaatcaaa tttatttaag acaatatgaa aagttcgttt atgatttgcc
    48121 attgcattat tagcaatcaa ttgcccccaa agtgatgatg ctgagatttt ttcatcatag
    48181 cctttaattg tagcgttttt gtgtgatgcc actaaaactt tacttgtaaa agaatcatcc
    48241 agtgccataa aagctacacc acttgcgtag ctagtagaca tagtgccgat agcccatcca
    48301 ttcgcatcat ctaaaccttt acgaattgca tgatcatttc ctgcaaaatc cgaactcata
    48361 gacgtatact catagacatt cccgattggt tcacttaaaa gtctatcaaa cagatcacgt
    48421 tgatctcctc catatgacat aagctttaat ccatacattt tttcatcata caaccgttgg
    48481 agtttaatta gctgttcgct gattttatta ggagaatcgg atactaatag gatttctagc
    48541 ttccaatcaa taattttatt tgccatgctg tctagtaaag atgctgtatt caaatccata
    48601 atccgcataa cagttttgct aatttcagca tctgaatttt ttccttctaa attattttca
    48661 taactattcg ttgatccccc aacattctcg tgcattattt cttgttgatc tttttgtgac
    48721 actggcttat ctgcttcaat tagataggct tttacccctt ctagtctcac ttcaggaata
    48781 gctttaacca tccaaccaaa tccataattt ctattcattc cataagtatt cactaatttc
    48841 acaattgttc cccaccgctt acctgtccta atgtaagatg gtgtaaattg ataaccaact
    48901 aaagatgtta aatcactaac aaaggtatta ttcactacct ttgaatttct agttttttgt
    48961 tcttttttag tttttctctt ttttttgaaa tttaatagtt gtgatctacc cataatttcc
    49021 atttaatctc tcacctctat ttcagtgcat aaatatcaga taatatttct tttgtttgtt
    49081 tagctgacaa ctgagtgaca ctataataaa gtcctctact cgtatagttt tctaaacgtt
    49141 ccacaccttc atccaatacc atcttagatt gagatttcaa gataagatat tggattactg
    49201 ttgttttcac accatcaata tattctgata caaatcgttc ttgctgatct attatgtcaa
    49261 agactgcttt gttactcctt gcatttcgtt tttgtatttt catatttcga gtttgtcgtt
    49321 ccgtattctg aggttgagat gaagtgattt tgatttcagc taaggaacga tctctggtat
    49381 tttgatattg tattgatttc gattcctgag ccataacttc ttctggaaaa gcggttagtg
    49441 atgtagcccc atctagattg aacattaatg ctacactccc atctcgatat acgattgttc
    49501 catcttgttt cacttttaaa atctctgtgc ctcgaaatgg tttcttttta cccatagata
    49561 ctcttgctga attaactact gatttgaaca gtctaataga accagaaatc aatgaaccac
    49621 tagatggatc aataaacata tactggctaa ttagaataag aaatccaatt atcattaata
    49681 acgttggaac aaaaataaat ttcagtttaa tcgtatcaga aactaagtaa acaattgatc
    49741 caagaacaac gactgcaaca actatagctg atacaattaa tctttttgct gtaacagaat
    49801 aggtgctatt gacatgcttt tcaagccatt caactctgac aattgtttca gaaggttttt
    49861 gatgtaagtt atgtttaaat ccatagtttg agttatctgc catcagaaat acttcctttc
    49921 acgttcaact tacggtaaac acctacagtt atcactattg caacaataag caagccaatt
    49981 aaagatattg acttgctcat tgtctcgttc gtttgtggta gttcatttac ctgatacacg
    50041 agctgtgctt cctgtaagtg ctgagaagag gtcatgtttt cttgattgtt ttgaattact
    50101 ggataaacta ttttttcttc tcgcataata gccctcctta gttattatca gataagtgag
    50161 cttgaatttt gtactgattt ccgtctggag ttttcacaac tgctttttct ccatcaatag
    50221 aaatcacttc agccttagtt gttttcccat caatactgat gacaacatct ttcccaactt
    50281 tgaactctgt agttggtgtt gcttcatagc tactatttgt tgaagcagag ttcgtatttg
    50341 tcccaatcga attttccact ctcgaaatag atgtttgagt ttgagcctgt gcttgttgat
    50401 tattatgact aataaagtag gacgatccca agatcgttcc gcaagccatt gcagcgacag
    50461 caatgatagt agccatcttt ttacttgtaa aatcacgttt tgaacttgat tgattttctg
    50521 tagcaactgc taatgatttc gttttttctg ccatttgagc tagatcactt cgggaacgag
    50581 ataagtcttc tcttaaagct tcactttgtt ctgccaactt ttcgctattt aatttataac
    50641 cctctgctaa atctttgacc tctttcattc gatctttata ttcttcgata gttttttgtt
    50701 gctctacaag ttttgtttct aattctttcg tgttgttagc tacctgcttt tcaacttctt
    50761 ctttgttcgc aaaatatttg acaaccacat ctgttgtttt ctcttttgta tcatggaact
    50821 cagcttcatt ttctgacttt gttttttcga caatctctaa agttttttct tgcacgtctg
    50881 ttaatgattt ttcaatttct ggtttcaatg aattgataat tcgttccacc acaacttctt
    50941 ttgcttcttg gctttgtttc aatgcatcgt ttttaataga ttcaattgct tcttggtact
    51001 gttgatcaag actttcttca gttgcttttc tatattcatc ttcttgttgt ttaacttctg
    51061 gtaaatgttc agcatcatac cgttgctcta gtttctttag ttcagcatcc aaataagcct
    51121 gtttcgccat atcataatct ttacgaatga tattggattt ttccatcact aaatcatcaa
    51181 ttttagatgc ttctgcttcg tagctctctt tagcaaccga tagtgtattt gtaaactgat
    51241 tttgaccatt taatgaggtt gcatcctcta tccgcaaaag ctcatcggct aacatttgct
    51301 ttcctttgag gatcaattgc tccttcgtct tatttaattc actgttgatt ttattattag
    51361 caatagagat acgagcgttc atactctctt tagctaaaaa cagcaatggt ttcaactcag
    51421 gtatggatag catctcctcg tttaaatcga cagggtcatt aatctcatct aaaactacag
    51481 gttgaaattt gtcagcaatg atctgttcaa aatttttttc taaaaaatca gcatctaagt
    51541 ttttcggtac atcactttca gatgtgattt tttcagcttc ataaacataa ttttctttgt
    51601 cactttggga ttcgggtttt tcatcaattt ttggttgttg gtaggtttct gtttgtattt
    51661 gtgtttcttc tatgcttact tcttggtttt ctgcttcggt tggtttgtta tcatccacaa
    51721 agagagcttc tttttcatct ggtacatctt ctgctacggc ttcaaattca acttcttcag
    51781 aagagttgaa ggtctcagca attcgttcta atccattagt agctacttct aattgctcta
    51841 ctgcgctata gaagtctgta gcttcttcaa cttctgattc aaacacatta ggatcatccg
    51901 gaataactaa taattgacca ctactatcca taaaacggac acctgctaat agcttctctt
    51961 taaatttttc tggtagatca gctacataat tcaaacttga cttcaataga acgacatact
    52021 tttcagaatc gagaatagca tcatcctcat ctataactcc ctcactgttg agcttttgta
    52081 catcttcaat taccatataa tttttctttg gtaaatcttt ggtcagcaac gcatcgaatt
    52141 ctttccatac ctttgcttta gctttttttg ccttcgcttc tttttcttct tttttgtaca
    52201 cttcgagtaa ttgtggcttc aaagagagtg caactacagg aactgtttct gccacataat
    52261 taatagattc ggtaatatct ttgaattttg ccattattgt aaaactcctt ttttcagtca
    52321 atagttcttt tctgtttgtc tagcatatat acatatgctt tttcgaattt aataagcgtt
    52381 tcaagtctgg ctttttcaat ctttttactc ccatttcgat aatcatagaa ctggttaaca
    52441 ttcatattca ttatctttgc cagttcggta cctttcagac tgctcattaa tacttcgttg
    52501 gcgtgagcta acattttttc tctatcaaaa accatcttac atttactttc ttccctcact
    52561 tctaaactac gcttggagcg tagttttttg gtaaaaagta aattgaacaa atcggcatat
    52621 tatccaaatt tgttcaattc acttttaacc taactgttca ttttttggaa attttgaaac
    52681 tagatagata ccaacaactg gaataagtgc tgatatgata ttagcttttt ggttcaaatc
    52741 attacctgtt ttagtaccca ttgtgtaaag cataacggtt gtaattacag gaataataaa
    52801 gattgcaata atcgccccaa catattttaa tccatctccc cattttgcat caccaaaaaa
    52861 tttcattgca gtgaatcctg gtttcaacga aaaaacgaat gccaagaaat acaaaacaac
    52921 ttgtactaaa gttttcatat caggcgtcat tccgctaacc aaatttttaa tagaatcgaa
    52981 catataaaaa cctccttttt aatattttta ataagttaat tatatcatcg acaaatctta
    53041 tttgttcact tgtcaatgat ctaactaaga aaaagacgtc tcgatattta catctttatg
    53101 ttatcataat aacataaatt ttcgatgatt aaaagagatt ttccattaaa ttatttcact
    53161 ttttttattg gctaaaaatg ctggtttatc aagtttttgt ttagataata attctgttct
    53221 ttaccagcga gagtataaaa tattttgtgt aaatgaaaaa atccatacaa aaaaggaag
//
LOCUS       DACDLM010000013        49398 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.013, whole genome shotgun sequence.
ACCESSION   DACDLM010000013 DACDLM010000000
VERSION     DACDLM010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.013"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            200..2734
                     /gene="secA"
                     /locus_tag="IV356_000791"
     CDS             200..2734
                     /gene="secA"
                     /locus_tag="IV356_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HAP9014500.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPHHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKSFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            2860..3961
                     /gene="prfB"
                     /locus_tag="IV356_000792"
     CDS             join(2860..2922,2924..3961)
                     /gene="prfB"
                     /locus_tag="IV356_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078989099.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HAP9014501.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRGLFDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            4066..4752
                     /gene="ftsE"
                     /locus_tag="IV356_000793"
     CDS             4066..4752
                     /gene="ftsE"
                     /locus_tag="IV356_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HAP9014502.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            4736..5629
                     /locus_tag="IV356_000794"
     CDS             4736..5629
                     /locus_tag="IV356_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9014503.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            5781..7229
                     /gene="cls"
                     /locus_tag="IV356_000795"
     CDS             5781..7229
                     /gene="cls"
                     /locus_tag="IV356_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAP9014504.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWVLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            7566..8423
                     /locus_tag="IV356_000796"
     CDS             7566..8423
                     /locus_tag="IV356_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HAP9014505.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            8538..9458
                     /gene="pstC"
                     /locus_tag="IV356_000797"
     CDS             8538..9458
                     /gene="pstC"
                     /locus_tag="IV356_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HAP9014506.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            9458..10342
                     /gene="pstA"
                     /locus_tag="IV356_000798"
     CDS             9458..10342
                     /gene="pstA"
                     /locus_tag="IV356_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HAP9014507.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            10357..11163
                     /gene="pstB"
                     /locus_tag="IV356_000799"
     CDS             10357..11163
                     /gene="pstB"
                     /locus_tag="IV356_000799"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAP9014508.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            11179..11937
                     /locus_tag="IV356_000800"
     CDS             11179..11937
                     /locus_tag="IV356_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAP9014509.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            11950..12627
                     /gene="phoU"
                     /locus_tag="IV356_000801"
     CDS             11950..12627
                     /gene="phoU"
                     /locus_tag="IV356_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HAP9014510.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            12865..13896
                     /locus_tag="IV356_000802"
     CDS             12865..13896
                     /locus_tag="IV356_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAP9014511.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGKLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGW
                     LFFFTSIFIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLLNISILFVV
                     IGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYLTRP
                     YRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSM
                     TNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLF
                     FLTVRRLKR"
     gene            13893..14660
                     /locus_tag="IV356_000803"
     CDS             13893..14660
                     /locus_tag="IV356_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAP9014512.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            14760..16328
                     /gene="liaX"
                     /locus_tag="IV356_000804"
     CDS             14760..16328
                     /gene="liaX"
                     /locus_tag="IV356_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HAP9014513.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            16628..16945
                     /locus_tag="IV356_000805"
     CDS             16628..16945
                     /locus_tag="IV356_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HAP9014514.1"
                     /translation="MKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVAF
                     GSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDEW
                     SDF"
     gene            16945..17295
                     /locus_tag="IV356_000806"
     CDS             16945..17295
                     /locus_tag="IV356_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HAP9014515.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            17462..18400
                     /locus_tag="IV356_000807"
     CDS             17462..18400
                     /locus_tag="IV356_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HAP9014516.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            18415..19245
                     /locus_tag="IV356_000808"
     CDS             18415..19245
                     /locus_tag="IV356_000808"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HAP9014517.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            19289..20314
                     /locus_tag="IV356_000809"
     CDS             19289..20314
                     /locus_tag="IV356_000809"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAP9014518.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGIGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            20329..21267
                     /gene="galU"
                     /locus_tag="IV356_000810"
     CDS             20329..21267
                     /gene="galU"
                     /locus_tag="IV356_000810"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAP9014519.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            21392..21832
                     /locus_tag="IV356_000811"
     CDS             21392..21832
                     /locus_tag="IV356_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HAP9014520.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            21835..22437
                     /locus_tag="IV356_000812"
     CDS             21835..22437
                     /locus_tag="IV356_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAP9014521.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(22496..23602)
                     /locus_tag="IV356_000813"
     CDS             complement(22496..23602)
                     /locus_tag="IV356_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAP9014522.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            23812..24813
                     /gene="ccpA"
                     /locus_tag="IV356_000814"
     CDS             23812..24813
                     /gene="ccpA"
                     /locus_tag="IV356_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HAP9014523.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(25150..27495)
                     /locus_tag="IV356_000815"
     CDS             complement(25150..27495)
                     /locus_tag="IV356_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAP9014524.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAK
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            27774..28676
                     /locus_tag="IV356_000816"
     CDS             27774..28676
                     /locus_tag="IV356_000816"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HAP9014525.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAEKGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQTFDPEVFPELLAEEVIL"
     gene            28889..30664
                     /locus_tag="IV356_000817"
     CDS             28889..30664
                     /locus_tag="IV356_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HAP9014526.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(30730..32316)
                     /locus_tag="IV356_000818"
     CDS             complement(30730..32316)
                     /locus_tag="IV356_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HAP9014527.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVSQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQNEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHAALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQLLQETVEEIE"
     gene            32566..32790
                     /locus_tag="IV356_000819"
     CDS             32566..32790
                     /locus_tag="IV356_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HAP9014528.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            32932..34683
                     /locus_tag="IV356_000820"
     CDS             32932..34683
                     /locus_tag="IV356_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP9014529.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            34683..36467
                     /locus_tag="IV356_000821"
     CDS             34683..36467
                     /locus_tag="IV356_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9014530.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFLAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     VLTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGI"
     gene            36793..37644
                     /locus_tag="IV356_000822"
     CDS             36793..37644
                     /locus_tag="IV356_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP9014531.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTITIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELFQVIQKKYKDTFGCVEKIADFLAETFNYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            37698..39449
                     /locus_tag="IV356_000823"
     CDS             37698..39449
                     /locus_tag="IV356_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP9014532.1"
                     /translation="MAKPSTNKLEGIEMGKYQELARKIVENVGGKENINGLTHCITRL
                     RFKLKNEEKANDEILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAV
                     STEKMRPFDMLIDGISGCFQPFLAILAAGGMIRGLTAFLVFLGAFDRGSGTFVMFDNI
                     GDSVFQFMPVIIGLTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSG
                     TIFEAPIYQTVFGIPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFF
                     TVLITMPLGFLLVGPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWA
                     IVPMGLMQFSVNGWQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVG
                     ITEPAIYGFTLPRKKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGD
                     LTDVINVLIGIAIAMVVSFTLTFFFWKDEAGETDDIQKKSGKEIVKTPIQGQIAPLNA
                     AKDAAFAQGTLGRGILIYPEKGEVRAPFDGTVMTLFPTKQAIGMVSETGLELLIHVGL
                     DTVQLEGKYFESLVQQG"
     gene            39453..39623
                     /locus_tag="IV356_000824"
     CDS             39453..39623
                     /locus_tag="IV356_000824"
                     /inference="COORDINATES: protein motif:HMM:NF012578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014533.1"
                     /translation="MKQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGET
                     VGPDDALITALT"
     gene            complement(39663..40565)
                     /locus_tag="IV356_000825"
     CDS             complement(39663..40565)
                     /locus_tag="IV356_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP9014534.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQAIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIHDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            40796..42199
                     /locus_tag="IV356_000826"
     CDS             40796..42199
                     /locus_tag="IV356_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAP9014535.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEENGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKEEGIEVQ
                     DELARELSGNTHIMEEV"
     gene            42199..43632
                     /gene="ascB"
                     /locus_tag="IV356_000827"
     CDS             42199..43632
                     /gene="ascB"
                     /locus_tag="IV356_000827"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAP9014536.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDAFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEKGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYASRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            43777..44703
                     /gene="trxB"
                     /locus_tag="IV356_000828"
     CDS             43777..44703
                     /gene="trxB"
                     /locus_tag="IV356_000828"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HAP9014537.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            44917..46644
                     /locus_tag="IV356_000829"
     CDS             44917..46644
                     /locus_tag="IV356_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HAP9014538.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAEKVASYE
                     AIIKKMTEE"
     gene            46716..47009
                     /locus_tag="IV356_000830"
     CDS             46716..47009
                     /locus_tag="IV356_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAP9014539.1"
                     /translation="MPDTQKSKVEKVSQLFKMLSDPTRLKILLYLKDGEQNVTAITQA
                     VEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHVLDILNQTLKHVEHQ"
     gene            complement(47101..47961)
                     /locus_tag="IV356_000831"
     CDS             complement(47101..47961)
                     /locus_tag="IV356_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HAP9014540.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLRQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            48053..48481
                     /locus_tag="IV356_000832"
     CDS             48053..48481
                     /locus_tag="IV356_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAP9014541.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            48643..48819
                     /locus_tag="IV356_000833"
     CDS             48643..48819
                     /locus_tag="IV356_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HAP9014542.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            48846..49292
                     /locus_tag="IV356_000834"
     CDS             48846..49292
                     /locus_tag="IV356_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HAP9014543.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
BASE COUNT        16012 a         8660 c        10596 g        14130 t
ORIGIN      
        1 gaaaacttgc agcagctact gacagctgcc gcaagttttt ttgagtttcc tcctctttta
       61 gatgaaatat gaataaatta tgaagttctt actttaatac gcttaagata tttcaattat
      121 ctataactaa tgataaaatg aaaagtaaag tctacatagt ctggataata cacagaagga
      181 aaaggagatt acacaacgca tggccaattt gattcgttca cttatcgaaa acgataagaa
      241 agaactaaaa cgtttagata gcattgcaaa aaaagttgaa gcatacgctg accaaatggc
      301 agcattaact gatgaacaat tacaggcaaa aactgctgaa ttcaagggca gataccaaaa
      361 aggagaaaca ttagatcaat tacttccgga agcttttgca gtcgtccgag aagcagcaaa
      421 acgtgtattg gggttatatc cacaccacgt acaattgatg ggtggaatcg tgcttcacga
      481 tggaaatatc cctgaaatgc gtactggtga aggtaaaacc ttgaccgcaa cgatgccagt
      541 atatctaaat gctctgactg gcgaaggggt acacgtagtt accgtcaatg aatatttagc
      601 aacccgtgac tcgacggaaa tgggcgaact ttataatttc ttaggattaa cagtggggtt
      661 gaatatcaac tcaaaatctt cggatgaaaa acgcgaggct tataattgtg atatcactta
      721 tagtacgaat aatgaattag gatttgacta cttgagagac aatatggtcg tttaccgcca
      781 tcaaatggta caacgtccgc tgaattatgc cattgtcgat gaagttgact caatcttgat
      841 tgatgaagcg agaacgccgc tgatcatttc agggcaagca gaaaaatcca cagctttata
      901 tacaagagca gacaacttcg tgaaacgttt gaaagaagaa gaagattata aaatcgatgt
      961 acaatcaaaa acaatcagtt taaccgaagc agggatcgaa aaagcagaag aaacattcgg
     1021 tttggataac ttatacgaca ttgaaaatac tgcattgacc catcacttgg atcaagcatt
     1081 gagagccaac tatatcatgc ttttagatat cgattatgtt gtccaagacg gaaaagtact
     1141 gattgttgac cagttcactg gtcggatcat ggatggacgc cgttattcag atggacttca
     1201 ccaagcaatc gaagctaaag aaggcgtaga gatcgaagac gaaacgaaaa ccatggcgac
     1261 gatcactttc cagaactatt tccgtatgta caagaaactt gcgggaatga ctggtacagc
     1321 taaaacagaa gaagaagaat tcagagaaat ttataacatc caagtatacc agattccgac
     1381 aaatcgtccg gttatccgtg atgatcgtcc agatttgctt tacccaacat tacaaagcaa
     1441 gttccacgct gtcgtgcaag atatcaaaga tcgctaccgc aaaggtcaac ctgtgttagt
     1501 cggaactgtt gcggttgaaa catctgagtt attatcagat atgctgaatc aagaacgtat
     1561 tcctcatgaa gtgctgaatg cgaaaaatca ctttaaagaa gcagagatca tcatgaatgc
     1621 tggtcaaaaa ggtgctgtga cgattgctac caacatggct ggtcggggaa cagatatcaa
     1681 gttaggactt ggggtaagag aacttggtgg tctagcagtt atcgggacag aacgacatga
     1741 atctcgtcgt atcgataacc agcttcgagg acgtgcagga cgtcaaggag accctggtat
     1801 gtcacagttc tacttgtcat tggaagatga tttgatgaaa cgattcggtt cagaacgaat
     1861 caaatctttc ttagatcgga tgaagatcgg tgaggaagat gctgttatcc aaagcaagat
     1921 gctgacgaaa caagtagaat ctgcacaaaa acgtgtagaa ggaaataact atgacacacg
     1981 taaaaacgtc ttacaatacg atgatgtgat gcgtgaacaa cgtgaagtaa tctataaaca
     2041 gcgacaagaa gtaatcatgg aagaaaaaag cttatccaag ccactaatga acatggtcaa
     2101 acggacaatc agtcgtgtag tagatgcgca tacacaatta gagaaagaaa attggaattt
     2161 ggaaagtatc atcgattttg ccggcagtac tcttgtccat gaagatagta ttactcttgc
     2221 agatatcgaa ggaaaaacag ctcaggagat caaagagtat ctaaacgaac gagcacaaga
     2281 agtatttaat accaaagcgg ctcaactaaa tggtccagag caactgttgg aatttgaaaa
     2341 agtcgtgatc ttgcgtgttg tggactctaa atggacagac catattgatg caatggatca
     2401 attacgtcag tcaatcggct tacgtgctta tggacagaac aatccattag tcgaatatca
     2461 aacagaaggc tataagatgt ttgaagatat ggtaggcgcc atcgagtatg aagtcactcg
     2521 aatctttatg aaagctgaga tccgtcaaaa cgtacagcgt gaacaggttt ctcaaggaac
     2581 agcttctcac tcagaagacg gagatgccaa agaaaatagt aatactagcg cgaaaaaaca
     2641 gccaatccat gtgaacaagg tcggaagaaa tgatccttgt ccttgtggaa gcgggaaaaa
     2701 atataagaac tgtcatggaa aaaatgcaaa ctaatttctg acagcaggat tggtgagaca
     2761 aattcttttt ttaagaattc gtctcacctt ctttctgtta tttgctgatt ctgttagact
     2821 agatataatg aaaaaagtat agtgaaagaa ggaaaaaaca tggaaatatc cgaaattcga
     2881 aatctcctga cagaaatgca ggaaaaggtc acaagcttca ggaggtctct ttgacttaga
     2941 ccagctggaa gaagacattg cggaagcaga agcaaaaatg gctgaacctg gtttttggga
     3001 tgatagcgaa gctgctcaaa aagtgatcag tgaaaacaat gcaaataaag aaacttatga
     3061 tcaattccat tctcttgctg aagaactgga agaaatcgaa ttgatggtgg agatgttgca
     3121 ggaagaacct gatgcagcca tgcaagaaga agcagaaaca cgtatcaatg cgctagatga
     3181 aaaaatgaag acatatgaat tatctatgtt gttagatggt ccttatgatc gaaacaacgc
     3241 catcgttgaa ttgcatccag gggctggcgg aacggagtcc caagattggg gcagtatgct
     3301 tttacgtatg tatacacgct gggcagagca gcatgggtat caagtagaga cactagatta
     3361 tcaagcaggt gatgaagcag gaatcaagag tgtgacccta ctgatcaaag gacacaacgc
     3421 atttggttat ctgaaatcag aaaaaggtgt tcatcgcctt gtacgtatct cgccttttga
     3481 ctcagcgaaa cgacgtcata cttctttttg ttcggtagat gtgatgccag agcttgatga
     3541 aacgatcgat atagaaatca atccagatga tttgaaaatc gatacgtacc gagcaagtgg
     3601 tgcaggtggt cagcacatca ataaaacaga atctgctgta cggatcactc acttgcctac
     3661 aggaacagta gtagctagtc aggcacaacg ttcacaattg aaaaaccgtg agcaagcgat
     3721 ggggatgtta aaagctaagc tttatcaatt agaagtggaa aagaaagaac aagaagcagc
     3781 tgcacttcga ggagaacaaa aagaaatcgg ctggggttca cagatccgtt cttatgtttt
     3841 ccatccatat tctatggtaa aagaccatcg gacaaacgta gagacaggaa atgtccaagc
     3901 agttatggac ggtgaccttg atttatttat tgacggctat ttaaaaatgc atctacaata
     3961 agaacccatt gttaaattga aataaaattg taagattttg caagcatgtt gaaacattgc
     4021 catgctataa tagctaaaga ctgaaaaaga tatggagaga acgccatgat tgaaatgaag
     4081 gatgtaatga agaagtactc aaatggtacg accgctatcc gcaatctctc aattgtcatc
     4141 gaacaaggag agtttgtcta tgtggttggt ccgtctggag ccggtaaatc tacattcatc
     4201 aaattgatgt atcgagaaga aaaagcttca aaaggaactt tgaacgtcgc aggtcatgat
     4261 ctaatagcaa tcaaaaaccg cgaagttcct tatctacgca gagaaatcgg cgtggtgttc
     4321 caagactata aattattacc aagaaaaaca gtatatgaaa atgttgcgta cgctatgcaa
     4381 gttatcggca gaaaacctcg ggatatcaaa aaacgagtaa tggaagtgct ggaccttgtt
     4441 ggtttgaaac acaaagttcg agtctttcct agcgaattat ccggtgggga acagcaacgt
     4501 gtctctattg ctcgggcaat agtgaatacg cctaaagtac ttatcgcgga tgaaccgaca
     4561 ggaaatctgg atccagaaaa ctcatgggaa atcatgaaat tattagatcg gatcaatgcc
     4621 caaggaacta ctgtcgtgat ggctacacat aacagtacga tcgtaaatac gattcggcac
     4681 cgagtaattg ctatcgaaaa cggccgcatt attcgagatc aagcggaagg ggaatatgga
     4741 tacgatgatt agaacctttt tccgccattt attagaaagt atcaagagtt tgaaacgtaa
     4801 cggctggatg acagttgctt cagtcagtgc ggtaacgatc acattgactt tagtcggtgt
     4861 attcatggca gttatcatga acgcaactaa attagctcaa gatatagaag gaaacgttga
     4921 tgtctctgta ttcgtagata tcggtacaaa agacgaagag atgaaaaagc tagaaaaaga
     4981 attgaatgac ttagatcatg ttaaaaaagt tgaattttca agcaaagaac aggaattgaa
     5041 aaaaatccaa aacgaaatgg gtgattcctg gaaattgttt gaaggtgaca ataacccgtt
     5101 atatgatgtg tatgtagtaa gtgctactga tccttcttat acaaaacaag tagcagaaga
     5161 agcagcagat ttgaagaatg tttctcgttc tgattacggt ggagcttcct cagatcggat
     5221 tttccaaatc gctggtgcag ttcggacatg gggattagtt gcagcggcat tgctgctgtt
     5281 cgtagcgatg tttctcattt cgaacacgat tcggatcacg attttgtcta gacagcgtga
     5341 aattcaaatc atgcgtttag tcggtgcaaa aaatggatat attcgctggc cgtttttcct
     5401 tgaaggtggc tggatcggtc tgatcggtgc gattcttccg attttgatca tcacatttgg
     5461 ttatgcatgg tttttccaat tgatcaatcc atcattatta cgttcccatt attcattgat
     5521 tcatccacaa aatatcgttt ggaaaatcaa tcttttaatg gtcggcattg gtgtgatcat
     5581 tggttcactt ggctcgatca tttctatgag acgtttcttg aaattctaat accacaatat
     5641 aaataaaatg agaaagttgg acagtttcgt tccagctttc tttttttatt ggctaggaga
     5701 atagaaggaa gcggcttttt tccctttact ttaaaaaaca acttgggtat tcttaagttg
     5761 gtagaagaag aggtgaagcc gtgaaaatta tcgttgacaa tttttttacg atccttttga
     5821 ttatgaatat tttgctttcc tttatcatcg tttttcgaga aagaaaggaa actgctcaaa
     5881 catgggcatg ggtgctcgtt ttgatgttca ttccagttgt aggatttatt ttatatattt
     5941 ttttaggaag agggatttcc aaagagaaaa tctttgattt gaagatccaa gggaaaatcg
     6001 gtaagaacct ggaaattgaa gaagacaaac aggcattgat gcgagggctt tatcctcatc
     6061 cgcctactgg acaagtagat gtgaaacaat tgatctatat gctcacggta tttgaaagta
     6121 cgctctatac gactaaaaat gaaatcactt tatttacaga tggtcgtgaa aaattcgatg
     6181 cgctgattga agatatcaag caggcagaag accatatcca cttccagtat tatatttatc
     6241 gcagtgatgc attaggtgaa gaagttcgag atgcattgac agaggcggca agacgagggg
     6301 taaaagtcag agtccttctt gatgcatggg gttccacaca agtttcttcc agcttttttc
     6361 agaatttgaa aaaagcaggc ggagaagtcg catttttctt tcctctattt gttccgtata
     6421 ttaatcctcg gatcaattat cgcaatcatc gtaaaatcgt agttattgat gggaaaatcg
     6481 gatatacagg tgggttcaat gttggaaatg aatatctagg attggtaaag aaatttggtt
     6541 attggcgaga caatcatttg cgtatttacg gagaagcggt gtataccttg caaaaccgtt
     6601 ttttgatgga ctggaattct cagcatacaa aagaagtagg ctattctccc aaattttttc
     6661 cgtccattca ctctactggt gatatagctg ttcaaatcgt gacaagcgga ccagataccg
     6721 aacatgaaca aatcaaaatg acttatttga aaatgatttc gttagccaaa cgggagatat
     6781 tgatccaaac gccttattac ataccggatg gatcgattca tgaagcactg aagttggctc
     6841 ttctttcagg cgtaaaagtt catatccaaa tacctaacaa accagatcat cttctcgttt
     6901 actgggcaac gtattctttc gctgcagagc taatcgagta tggagcaagg atcgaaacat
     6961 atgagaatgg atttattcat gcaaagacga tgattatcga tggtggcatt gtttcagttg
     7021 gctcagcaaa tatcgatgtt cgttcatttc gcttggactt tgaggtcaat acactggttt
     7081 atgatgaacg aatggcttca cgtgtaagaa aagctttttt tgaagactcg aaaatttcta
     7141 cgcatctcac aaaagaaatg tatgaaaacc gaggaataat catcaagatg aaagaaggat
     7201 tagcaagatt gatttcgccg ctcctttaaa acataaaaag gacatgagaa ccatcaacag
     7261 atggagatct cgtgtccttt tctaacgggg ccatttctga gagtacgtca gaaatggaga
     7321 aagcgtctcg catgagcgaa attaactttg gggtatctct tgttttttgg ggaaagcaag
     7381 aaataagcta atatatgcta ttaaaagaga cacatttcaa agccagtata gcatagaaac
     7441 ttttaatgag atagtttttt ttacaattat gagaatttat tttgttattt aatgattttg
     7501 attcgttttc atcaagtaat gaaaatgata aaataaacat actttaggat taaaggagat
     7561 ttctaatgaa aaaacttaaa ttattcttac caataatagg attagctatt cttttatcag
     7621 gctgttcaaa gtggattgat cgaggagaat ccattacggc tgttggctct tctgctttac
     7681 agcctttagt agaaacagtt gctgaaactt accagacaga aaatcctgga aaattcatca
     7741 atgtacaagg gggcggaagc ggaactggtt tgtctcaagt acagtcagga gcagtcgaca
     7801 tcggaaactc tgatttgttt gcggaagaaa aatcggggat cgatgcctca gcattagtcg
     7861 atcatcgagt agcagttgtt gggatcactc ctattgtgaa caaggatatt ggcgtaaaag
     7921 acatcagtat ggaaaacctg aaaaaactat ttacaggcga gatcaaaaac tggagtgaag
     7981 tcggtggaaa agatcagcca gtagttatat tgaaccgcgc ttcaggaagc ggaacccgta
     8041 gcacgtttga aaaatgggta ttggacggag aaacagctgt tcaggcacaa gaacaagatt
     8101 caagcggaat ggtgcgccag atcgttgccg acacacccgg tgcaatcagc tatgttgctt
     8161 tttcttatgt ttccgatgat gtagatacgt tgaatgttaa cggtgtagaa ccgacagatg
     8221 aaaatgtgac aacgaacaaa tggacgattt gggcatatga gcatatgtac acaagagatc
     8281 atccaaaaaa actgacaaaa gaatttttag actatatctt atctgatgaa gtacaagata
     8341 acatcgttgg agaactaggt tatatccctg tttctcatat gaaagtcgaa cgtgattggc
     8401 aaggaaatat cgttaaagag taatctttac acaaaattta caaacttagc taaactttta
     8461 catgttatta aaaccaaatt gatgttcaat ttgtacactg agtgagtatg ttaaacctga
     8521 ttaaggggga gtcatctgtg gaagatgtga aaaaagtatt attaacaaaa tcaaaacgtt
     8581 caaaaatgga acagcgtgga aaattcatca gttttttatg tatcgcgctg atcgtgttgg
     8641 ttgtattatc tattttttat tttgtagcta gtaaaggatt ggccaccttt tttactgata
     8701 agatcaatgt atttgatttt ctgtttggta cagattggaa tccaagccaa atcggagcaa
     8761 atgggaaacc aatggtaggg gcattgccta tgatcacagg ttcgtttatt gtgacctttt
     8821 tatctgctat cgttgccacg ccatttgcca ttggtgcagc agtattcatg acggagatct
     8881 ctcctaaaaa cggaacgaag atcttacagc cggtcatcga gctgcttgta ggtattcctt
     8941 ctgtcgttta tggttttatc ggtttatcag ttatcgtgcc ttttgtcaga agtatttttg
     9001 gcgggactgg gtttggtatc ttagctggta catttgtgtt gttcgttatg atcttgccga
     9061 ctgtcacaac gatgactgtt gatgcattaa aggcagtgcc acggcactat cgggaagctt
     9121 cattagcgct tggtgccaca agatggcaaa caatctacaa agtcgtgcta cgagcagccg
     9181 tgcccgggat tttaacagca gtcgtttttg gtatggctcg tgcgtttggt gaagccttag
     9241 ctatccaaat ggtcatcggt aatgcagcat tgatgccaac aggtcttact actcctgctt
     9301 ctacattgac gtccatctta acaatgggaa tcggaaatac aatcatggga acagttgaaa
     9361 ataatgtgtt atggtcatta gcgctgatct tgctattgat gtcattattc tttaatatcg
     9421 tgatccgtat gattgggaag aaaggagagc tgaaataatg aacgcaaaac gctcagataa
     9481 aattgctaca ggtgttttat atatagtttc ggggatcatc gtattgattt tagcagcttt
     9541 actactttat atcttagttc ggggaatacc gcacatttca tggtccttct tgaccgaacc
     9601 ttccaaagcc taccaagaag gcggtggaat cgggatccag ctatttaact cgatttattt
     9661 gcttttgatc acgatgatca tcagttttcc tatttcttta ggtgcgggta tctatctttc
     9721 agaatatgct ggaaaaaact ggctaacaga tgtgattcgc acgtcgattg aaatcttgag
     9781 ctcgttgcct tctgtcgttg tcggtttatt cggtttcttg gttttcgtta ttcaattcca
     9841 gtatggtttc tcgattattt ctggtgcatt ggctttgact gtattcaact tgcctctttt
     9901 gactagaaca gttgaggagt ctttacaagc ggtccattac acacaacgag aagcaggatt
     9961 ggccttaggt ttgtcacgct gggaaacagt gataaaagtg gtggttccag aagcgacacc
    10021 agggattttg actggtgtga tcctaagttc tggaagaatt tttggtgaag cagctgcatt
    10081 gatctatacg gctggacaaa gtgcacctgc gttagatttt acgaactgga atccattaag
    10141 tgtttcaagc ccgatcagca ttttccgtca agctgaaaca ttagctgtcc atatttggaa
    10201 gatcaataca gaaggcacga tgcctgatgg tgtttctgtt tcggctggcg cttctgccgt
    10261 gttgattatt gctgttttac tgttcaactt cggcgctcgt gcgattggca aacgattata
    10321 ccgaaaaatg acttcagcct aaggagaaga agcaaaatga aaaaatataa ctggaatgaa
    10381 acaaatgtca tcaccatgcc aaaagagaaa gaagtagcac tatatacgga tgatctacat
    10441 gtctggtatg gcgacaatga agcaatcaaa ggagtggatc tggaatttga aaaaaataag
    10501 atcactgcac tgattggtcc ttccggctgc ggaaaatcta cgtatcttcg ttcgttgaat
    10561 cgaatgaatg atgggatcgc taatacgaaa atcactggga aaatcatgta tcaaggcgta
    10621 gatattaatg cgcctcaagt ggatgtttat gagatgcgca aacggattgg catggttttt
    10681 caacgtccta atccgttcag caagtcgatt tatgacaata ttacatttgc tttgaaacag
    10741 cacggcgaaa aaaacaaaaa gaaattagat gaaatcgttg aaacaagctt gaaacaagct
    10801 gccttgtggg accaagtaaa agacagcttg gacaaaagtg ccttggcttt atctggcggg
    10861 caacagcaac gtttatgtat tgctcgtgcg atcgcgatga aacctgatat cttgctgcta
    10921 gacgagccgg caagtgcttt ggaccctatt tcgacaggaa cggttgaaga aacacttgta
    10981 aacttgaaag aagactatac gatcatcatc gtgacgcata acatgcaaca agcagctcgt
    11041 atcagcgact atactgcctt tttctattta ggaaaagtaa tggaatatga caaaactaac
    11101 aagatattta ccagaccaaa aattcaggca accgaagatt atgtgtccgg tcattttggt
    11161 taagacggag gcctcaacat gacaaaagag attatttcat ctaaagatct tcatctgtat
    11221 tatggaaaga aagaagcact aaaagggatc gatctaagct tcaatcaagg ggaaatcact
    11281 gcgatgatcg gtccttctgg ttgcggaaaa tccacttatc tgcgttcttt gaaccggatg
    11341 aatgacctga ttccgaatgt aacgatcacc ggaagtgttt tatataaaga caaagacatc
    11401 tatggtccaa aaacagatgt tgttgaacta agaaaagaaa tcggcatggt attccagcag
    11461 ccaaacccat ttcctttttc tatctatgaa aatgtcatct atggattgaa attaaaaggg
    11521 gaaaaagata aaaaagtcct tgatcaagta gttgaagaaa gcctgaaggc agcgtctgtt
    11581 tgggatgatg tgaaagacaa attgcataaa agtgctttat ctttatccgg tgggcagcag
    11641 cagcgtgtat gtatcgcacg tgttttggca gttaatccgg aaatcatctt attggatgaa
    11701 ccaacaagtg cgcttgatcc tgtttctact gggaaaatcg aaagtatgct gttagaatta
    11761 agagagcggt atacgatgat catcgtgacc cataatatgt ctcaagcttc acgtatttca
    11821 gataagacgg cattcttttt agatggtcac ttgatcgaat acaatgatac gaagaagata
    11881 ttcatgaatc cagaaaaaca agagacagaa gattatattt caggtcgatt tggataagga
    11941 ggaaacggaa tgctacgtac acaatttgaa gaagaattgc tgaatctcca taatcagttc
    12001 tacgaaatgg ggatgatggt gagcagcgcc gtgcacaagt cagttcgtgc atacatcaaa
    12061 cacgataaaa tcttagccca agaagttatc gaaaacgata taaatatcaa taacatggaa
    12121 acacgcttgg agaagaaaag ttttgaaatg atcgcattgc aacagccagt tacaactgat
    12181 ttgcgtatga tcattacggt catgaaagct agctcggatt tagaacgtat ggccgatcat
    12241 gcggtgtctg ttgctaaatc cacgattcgc gtaaaagggc agacgagaat accggaaatc
    12301 gaaaaagaga tctccgatat gtccgattat gtgaaaaaaa tggtggacaa cgtcctagtt
    12361 gcttatgtca aaacagacga aaaagacgca cgtacgatcg ccaatatgga tcaaagagtc
    12421 aatgactatt tcaatcgaat ctataatgca acaatcaaaa atatgcagga aaatcctgag
    12481 acagtcatca gtggaacaga ctacttgaat gttgccagtt atctagaacg gatcggagac
    12541 tatgtgacaa acatctgtga atggatcgtc tacttggcta cagggaaaat cactgagtta
    12601 aatacgaacc acaatgagat tttctaaact gaagctgtga ttatgccgtt tgtttaggaa
    12661 aagaggttgt gaaatcagcg gttgtgaaaa agctgttctg catcaagtaa taagaacagt
    12721 caaacaaaaa atagctcctc atatttttcg tttggctgga cttattaccg cagatgcaag
    12781 cttttgaaca ccgtttattc gggaaagggt ttgtgacaaa acatgtcaca aacccttttc
    12841 atcatttcat agaaaggata aagaatgcaa aaaaaaatta gcatcatcac tatatttttt
    12901 atttgtgtgc ttacttcatg ggttattcag catcaagccg ctttatatga agtacctgtc
    12961 atcgagatag aaaaagtacg aataaaagag gatcatcaat tgattacagg aaaactgatg
    13021 aacacggatc aaaaaggaga atcgatttat ttatcggttc cttatcaaaa aaatcaaata
    13081 gaaacagcaa atataaaagc gagacaaatg tatctagtcc aaatgcatgg agatgaatgg
    13141 cagctagtag caaaaaaaaa tgatggctgg cttttcttct tcacaagtat cttcattggc
    13201 gccatgttgc ttattggtgg aaaacagggt ctatttgctt taggaagtct catcatcaat
    13261 atcgttttac ttttactttt gttgctcatc tttactaaaa cagaagggat ttctctatta
    13321 aatatatcta tcctgttcgt cgttataggg atgattatta gcatattggc tttagatgga
    13381 tggaatagaa gcagtataat caaaatttca gctgcagtta cgagtgtttt tttagcattt
    13441 tttatttgtc ttttgacaat gaatcattgg aaagaccaag gactgcgcta tgaggaactg
    13501 aattatctga cacgaccgta tcgttctgtt tttctttcta gcgtactgat tggaacagct
    13561 ggaggaacac tcgataccgt tatcacagtc attgcgacat tagaagaatt gactaagcga
    13621 caaccagaaa taacagcgaa acagttatgg ctttcaggaa ggcaagtggg tcgagatgtg
    13681 attggctcga tgaccaatat ccttttgttc gtctatatca gtgggtcagt tccatcgctt
    13741 cttttatatt taggaaatca atggtcgttc aaagaaacga tagaacagca tttatcattg
    13801 gaatttttac gcgtcattgc tggcagctta ggaatagtat tatcgatccc tatctcggtc
    13861 ctcttttttc tgactgtaag gaggctgaaa cgatgaatgt acttattata cttgttggga
    13921 ttttagcaat cagcgtgcta cttattggcg gtacgcaagg tatgtatatt cttttaggct
    13981 tattcatcaa tttagggatc tttttcctgt tgttattcgg ttatcatcag aagtggccga
    14041 tactggcatt gtcggtcata ggatttttat tgattgctgt ggttatctta ttttttatca
    14101 acggttataa tctaaaaatg cgtgcagctt ttgtgagtat actgatcttt ttattttgtt
    14161 tcctactatt gcttcctatc actgattttt tagcaatcca aggttttaca tcggtagaac
    14221 tagaagaatt atctggctta gataagactt tagcgattga ttttagatta cttacgagat
    14281 cgttgcttct gattagtctt agtggtgctg ttttagatgc gagtgtagca atttctagtg
    14341 ggacattcga agtatatcag gcaaatccgc aattatcttt ttaccaattg cgccattcta
    14401 gtttcgctat tgctaaaaaa atattggcgt caacagtaat gacacttctt tttgcattca
    14461 tgggaagttc tttagcgttg atcctctggt ttattgattt agacattcct tttcagcaag
    14521 tgatcaatga aaaatcattt gttctagaat atacgatggc tattcttacc acattgtccg
    14581 cactacttgt tcttccttta acctgcgtga ctacagcata tctctttaca aaaaagaaag
    14641 aacaactcaa gatggagtaa aagttacaac ttaagtccta tgacattttt actgaatcag
    14701 tgcataatat ggatgtaagg aaaagcttgc aaacaatttt gcttaaggag gcaatttcca
    14761 tgaaagaaag agaacgtatt ttagatttag tgaaaaaagg aatcctttcg actgaagaag
    14821 gcttagattt attagaaagc atggcaactg aaaaagacga aaagcaaatc aaaaaagaag
    14881 cagacaaggt aactgctagt cataaagaaa aagatcaggc aagtcaattg atcgataaac
    14941 ttgaaaacgg cgaagaagaa atttctgagc cagttgatcc aaaggaaaga gaaagacaag
    15001 atcaagaaaa cttagaaaag atcttagatg aactagcaac tgaagcgaat aaaacttcgg
    15061 cgcgtctaga tgaagtaaat gctcaattcg ctgacaataa ggcagcacgc aatgagaaac
    15121 aggaagcatt gatgcagctg aatacaaaag aagaattagg cgagttgaca gaagaagaat
    15181 tagcacagcg tcagacgtta gaagcagaaa tcaaagaatt agaagctagt ggcgatacac
    15241 tgttagaaga acaattgaaa ttagaagcag aattaaaaga tatccgtaag aatcaatggt
    15301 ctgagaaaaa agaaacgttt actgataagt ttgaattgcc agatgattgg aaagatcaag
    15361 caacagatac actgaatcaa gtaggcgaaa aaatgtcaga agctggatca cagttaggca
    15421 aattcttgaa gaaaacattc caaactgttt cagaaacagt gaatgacaac atggaatgga
    15481 aagatgtcag cttacgtgtc cctgggattg cgacaacgaa atttgagcat gaattttact
    15541 atgaagctcc tgcagcaagt atccttgata tcaaggcagc aaacggaaac gtgacgttaa
    15601 aaacgtggga cagcaacgat gtgaaagttg aagctaagat caaactttac ggaaaaatgg
    15661 gtgctgaacc atttgaagca ttctctgaac ggagccagat tgaggttaat gaagatcata
    15721 tctccttcca aattccaaat aaacgtgtgc gtgcagacct tgttttctac ttacctaaac
    15781 gagtatacga ccacgcagct attaaacttc taaatggcaa catcatgatt gaaacattgg
    15841 aagctaaaga tatttataca aaatctacga atggtaacat catcgtggac caattaactg
    15901 caacgatgct ggaagtagaa ggtgtaaacg gcaatatcga tattcgaaac gggaacatct
    15961 tagattctat tatcgaaaca gtaaatggta cagtgacatt tggtgcgaca gcagaaaacc
    16021 tttctgtgtc tttggtaaat ggtgatgtac gtcttacgat taaagaagat aatttgaaaa
    16081 aagtagaagc aagttcagtg aacggaaatg tcaaagtcgc tttaccagat ggcatcggtt
    16141 tggaaggaca tgctaaaaca agtcttggaa gtatcaacag ccgtctgtcc aattacgaag
    16201 tagttcgtga gaaaaaagaa cggacaaacc aaatgttgca attccgtcgt gtttcagatg
    16261 gtgaaatcgc gcaagtgcaa ctttcaacga caacaggaag tatctattta aaagatacag
    16321 ataaataaag aggttgtgaa agagatgttc agccttgagc aataagaagc gattttgtaa
    16381 aatagcttcc cctattttac aaaattgtgc cttattgccg atagtctatc tcttgaacac
    16441 cgtttaccaa gagattatga acctgccaat tatcgccgag tcacaaggaa taatttcaga
    16501 aaaagctcgt cacgttttat gaatatggta atttgtgacc gagaattttg cagaaagaca
    16561 ccgattaaga agaaggttgt cacaacgatt ttcttcattt aaaatagtag aacagaggtg
    16621 agacatgatg aaaaaaaagt tgacaaaatc taataaaaat gttgttttga cagggacttt
    16681 agcaggaata ggagaataca tcgggattga tccgactgtt atccgtgtgc tttatgtatt
    16741 cctgagctta gttgcttttg gaagtccaat tattttatac attttattag ctttgattat
    16801 cccatctgcg cgttctgcac gaacaaacta tggacataac aatgcatatt atgaaaaaaa
    16861 caattatcgt gaacaaactc gtgaacaaac aaaaaaacgc aaagaagcgg aaaaaatcga
    16921 tgatgacgaa tggagtgact tttaatgtcg tactttcaac gtattttagt taatacgtta
    16981 acattcatat cattggctgt tctttttcct gcgatggtcc atgtgagcag tatttggacg
    17041 gccgttcttg ccagcttcgt attgtctgtg ttgaatatgt ttgtcaaacc gattttgacg
    17101 atactgtccc tgccctttac attagtcaca ttgggattgt ttacgtttgt tatcaatgca
    17161 gcgattctta aaatgacctc cttttttgtg ggagcagaac attttagttt ttcttcattc
    17221 ggtgcagcgt tgttagtagc tatcttgatg tcgcttgtca atgtaattgt cagcgaacat
    17281 aacagtagaa aataaaagaa agctgtgccg aactatcggc gcagtttttt tatttagaat
    17341 caggaatgcg ttttctatta cattggtaat taaataaaaa cgtttttttt aattggtagt
    17401 acttttggct agacaatgat aaaatgatag agaacactct aatagaaatg aggtagcatg
    17461 aatgtcagaa gttgtaaaag ttagccaatt agtgaaaaaa ttatctttgg aaatcgtgac
    17521 aggcgacgag aaaagcttag accgtgtcat cgtaactggg gacatctcac gcccaggact
    17581 agagttgact ggttatttta attattattc ccataatcgt ttacagctat ttggcagtaa
    17641 agaaatcagt tttgcggaac ggatgatccc agaagagcgt ttgatcatca tgagaagatt
    17701 atgtagtgaa gatatgcccg catttattat ttcaagagga ttaccagctc cagaagaaat
    17761 gatccaggca gcaaatgaaa atgggatagc tgtactgcgt tctcccatct caacttctcg
    17821 tttattagga gaattatcca gttatttaga tggtcgcctt gcccctcgaa caagtgtcca
    17881 cggtgtttta gtggatgttt acggattagg tgtactgatt caaggtgaca gtgggatagg
    17941 aaaaagtgaa acagcgttgg agttgatcaa acgcggccat cgattgatcg cagacgatcg
    18001 agtagatgtt tatcagcaag atgaattaac ggtgatcgga gaaccgccta aaatcctgga
    18061 acatctgatt gaaatccgag gaatcgggat cattgatgta atgaatcttt ttggtgcgag
    18121 tgcggtacgt ggctctatgc aagtccagtt ggctgtttat ctggaagcat gggcaaaaga
    18181 taagaaatac gaccgtctgg gctctgaaga cacgaccgtt gaaatcgcgg aagtgggcat
    18241 tccacaaata aaaatccctg tcaaaacagg acgaaacgtt gcaatcatca ttgaagtagc
    18301 cgcgatgaat ttccgtgcac gtacaatggg ctttgacgca acgaaaacat ttgaagaaag
    18361 attaagtcgc ttgattgaag aaaactcagg caacgactag caaggagtga caatatgtta
    18421 gcacaaatca atcgagttgc ttttgagctt gtagggattc ctatctactg gtatgcattg
    18481 atcatcgtat caggtatcat tatcgctatg tggcttagca gcagagaggc tgttcgggta
    18541 ggattaaaag cagatgatgt gacagatttt atgttgtggg gattgcctat ctccattatt
    18601 ggcgctcgct tatattatgt tttatttgat cttccccagt atatagctga tccaatccaa
    18661 atattcaata tccgttcagg aggcttagct atttatggcg gactgattgc aggcgcgatc
    18721 acgctgtatt tttttactaa atatcatttt atttctttgt ggactttttt agatatcgct
    18781 gcaccaagtg tattattagc acaggcaatc ggtcgttggg gaaatttcat gaaccacgaa
    18841 gcatatggac cagacacgac gcgaagcttc ttagaaagtc tgcatttacc gcaattcatc
    18901 attgataata tgtatatcga agggatctat cgtcaaccaa catttcttta tgaatcactt
    18961 tggagtttga ttggatttat tttgcttttg tttttacgaa agaaaccaca ccttttgaaa
    19021 aaaggcgaag tccttttatg ttatctaatg tggtatagtt tcgggcgttt ctttattgaa
    19081 ggattacgta cagacagtct ttacttttta ggtgtgatcc gtatttctca attattatct
    19141 gctgtgttat ttgtcggtac attgattcta tttatttggc gcagaaaaaa aggaaattta
    19201 ccggattatg accgctcatt aggaaaaaat caacaaatta tctgattttt agagcgttaa
    19261 aaatgaaaaa aatttcagga gtggtaaaat gaattataga gtagcggttt taggaccagg
    19321 ctcttggggt actgctttgg cacaagtcct cgccgaaaac ggacatgacg ttcggatttg
    19381 gggacatcgt gcttcacaag tagaagaaat caacacccaa cacacgaatc aacgttattt
    19441 accagatcat tatctacccg attccatcca agcattcacc aatatggaag atgcagtaaa
    19501 agacgcagat gcggtgctat tcgtcattcc aacgaaagca atacgttctg ttgcaaaaga
    19561 actagtgcct aaattgaata caaagccagt gatcatccat gcaagtaaag gattagaaca
    19621 gggaacacat aaaaggatct ctgacatctt gttagaggaa atcccagcag aaaaaagaaa
    19681 agctgttgtt gttctttctg gaccaagcca tgcagaagaa gtagcaaaac atgacatcac
    19741 tacgatcaca gctgcaagta cagatgcaaa agcagcaaaa tatgtacaag agctgttcat
    19801 gaataattat tttcggatct ataccaatcc tgatgtgatc ggtgtagaga tgggggcagc
    19861 tttgaaaaat attattgcta ttggtgctgg cgctattcac ggcttagggt ttggcgataa
    19921 tgcaaaggca gcaatcatga cgcgcggatt agctgagatc agccgtttag gtgtagcaat
    19981 gggtgccaac ccgctgacct ttatcggatt aagcggaata ggcgatctag tcgttacttg
    20041 cacaagtgtt cattctagga actggcgcgc aggcaacttg ttaggacaag ggcagcccct
    20101 agaagaggtg ctagccaata tgggaatggt cgttgaaggt gtgaatacta cccaagcagc
    20161 gatggaacta gcccaaatga tggaaatcga aatgcccatc actcaaacaa tctatgaagt
    20221 gctgtatgaa caaaaagaaa tcaaaacagc cgcaaaagaa atcatgttac gtgatggaaa
    20281 aaaagaaaat gaattctcat taacaatttt ttgaaggagc gaatgtatat gaaagttaaa
    20341 aaagcagtta ttccagcagc aggattagga acaagatttt taccagcaac aaaagctatg
    20401 gcaaaggaaa tgttgccaat tgttgataaa ccaacaatcc agttcatcgt tgaagaagcg
    20461 ttgaaatcag gtatcgaaga catcttgatc gttacaggaa aagctaaacg accaatcgaa
    20521 gatcactttg attcaaatat tgaattagaa acaaacctaa gtgaaaaagg aaagaccgaa
    20581 ttattgaaat tagtagaaga aacgacagat gtcaacttgc atttcatccg tcaatctcat
    20641 ccaaagggtt taggacatgc cgttcttcaa gcaagagcct ttattggaaa tgaaccattt
    20701 gtcgttatgc taggcgatga tataatggaa gacgaagtac cattgacaca gcaattaatc
    20761 gatgattacg aacgtactca tgcttctacg atcgccgtta tgcaagttcc tcatgatgaa
    20821 acttcaaaat acggaattat caatccagga gaagtattgg aagatgggtt atacaatgtc
    20881 aaaaactttg ttgaaaaacc agatccaagc aaagcaccaa gtgatttagc tattattgga
    20941 cgttacttat tgactccaga aatttttgat gtattgtccg agcaacaacc aggagccgga
    21001 aatgaaatcc aactaactga cgcaatcgat acattgaata aaacacaacg cgtatttgcc
    21061 cgtaaattca caggtaaacg ttacgatgtc ggtgacaaat ttggttttat gaaaacaagt
    21121 attgaatatg gtctaacaca tccagaagta ggtgcacctt tacgtgagta catcctgtct
    21181 ttaggtaaaa cattagaagc agaaggaagc aagatcgatc ataatccaaa aggaataaca
    21241 gaaatcaaag aagaaaagaa aaaataaccc ttttttctaa cgagcttcag ctgctaattg
    21301 aataaaaagt agttgaagct cgtttttatt tgtttaaaaa acacgaaaat gctatcctta
    21361 tagaaaagag agacaagaag ggagtttgat catgtcagga ggagaaattg caggattgat
    21421 cgcagcaatc gcctttgcga tacttgtcgt ttttatcgtt cgtgtgttgt tgcaagtttc
    21481 taaaacttta gaaaaagtag atcagactgt agcagaagca aatacgacga tcgaaatcgt
    21541 cacaaaagac gtagatcttt tgtctagaca agtagaaggc ttactggtca aaagtaatga
    21601 actgctcttg gatatcaatg gaaaagtcgc aacgatcgat ccattgttca cagcagttgc
    21661 tgatttaagt gaaagtgtat cagaacttaa tcattctagt aaaaacatcg cgacgaaagt
    21721 cggcggaatc ggtaaaacga cagctaaagc gacggttgcc ggaaaagtcg gtgggacagc
    21781 gatgaaattt tttaaaaaca aaaaacatac tgaaacgaca ggaggaaaat aaaaatggct
    21841 aaaaaaggtg gatttttatt aggtgcagta gtcggaggca cagccgcagc aatcgccgcg
    21901 ttattgttag caccaaaatc tggtaaagaa cttcgggatg aattagctgc ccaagcggat
    21961 gatttgatgg atatggcttc agattacaca gatatggcga aagaaaaatc gactgagtta
    22021 acaggtattg caaaagaaaa agcgcaagat ctttctcaac aagcaggtga tctagcaggt
    22081 agtgtcaaac aaaaagtaag tgaatcagca gatgaagcag gaagtgaatc tgacgatatc
    22141 ttgttaaatc ttaaagaaca atcagctgac ttatctaatc gtttcaaaaa aacggcagaa
    22201 gatatgaaaa aacctgcaga tgaattagga agtattgcta aagatacttc agaagatatc
    22261 atgattgatg taaaagacgc tgctggtaaa gcaggagata ctgtcaatga aggaatgtca
    22321 gaagcaaaac cagttgcaga tgactcaaaa gaaatgatga aaatggcaaa agaagatgcg
    22381 aaagaagcta aaaaagaaat aaaagataca atgacagatt catctacaaa tcactaaaat
    22441 cacaaattta tagaataaaa aggtgggagc ggactagctc tcaccttttt tactcttatt
    22501 tttctaaaac aagtaattct tttggtgtag tcgtgaatgg cacacagcca tcgcttgtca
    22561 catatacaca gtcttcgata cgtaccccta ctttttcagg aatatagatt cctggttcaa
    22621 gagagaagca catcccttct tcgattacta agtcatttcc ttctacaagg gaagggaatt
    22681 cgtggacggt tgttccgatc ccgtgaccta aacggtgatt gaaatattcg ccgtagccat
    22741 agctgttgat cacgtttcgt gcgatttgat caagttcacc tgctgtcaca cctggacgga
    22801 cggcttcttg tgcggcaagc tgtgcttcaa gagtgatgtt gtagattttt tcttggaagt
    22861 cggttggttt ttgataagca attgtacgag tagcatcact gcaatagcca ttccaaacaa
    22921 cgccaagatc gaataacaca agttcattcg gtgaaatctt cgtatttcct ggtgtaccat
    22981 gagggcttgc agcatttgct cctgcaagga ctaatgtgtc gaaagacatt tgtgaaacac
    23041 cttgtttttt caattggtat tcaatttctg caatgatcgc ttgttcagtc acgccttctt
    23101 tcactgcttt aaagccaatc tcaaatgcaa catcggccca tttaccagct tcgatcagtt
    23161 tgtctttttc ctctagagtt ttgatcagtt gtagacgttg gatgatggaa gttagatcag
    23221 tgtaagaatc cgttcccgtc aagatatcag agatagcatc gaagcgctcg acagtcaagg
    23281 cgttcttttc aatccctaca ttgccaggct gaccatagcg agcacgaagt tcttttccga
    23341 tgatctccca agggttttcg ctgtctaaat agccacggac atcatacgcc caactactgt
    23401 tttgagcatc ttcaacttcc aaagcaggag tgaaaaggaa aggatcttgt tcaagaggga
    23461 taaaaagagc tagtacacgc tcatgaggat cactttcgta tccggaaaag taagcgatgt
    23521 ggccagggtc gctgatataa gccaattcga cttggtgttg tgccatccat tgacgtagtt
    23581 cattgatttt tacgttattc atttggcaac ctactttcta aattaatttt gtattcaata
    23641 attgtaccac tgatttatta aaagaccaac gttctaaaaa ctgaaaaaag taaaaatttt
    23701 catgaaaaca gagataaaac ggttgcaatt cttgagatta tttgatattc tattttagaa
    23761 atgtaagacg tattttcaga aaacgtataa aatatgaata ggagaacaca aatggaaaag
    23821 caaacaatca ctatctatga tgtagcgaga gaggcaaatg tttcgatggc tactgtttca
    23881 cgtgtcgtaa atggcaatcc aaacgttaaa ccagcaacaa gaaaaaaagt cttggaagtt
    23941 atcgatcgct tggattatcg tccaaacgca gttgcgcgtg gcttggcaag taagaaaaca
    24001 acaacagttg gtgtaatcat ccctgatgtc agcaatatgt tctttgcttc tttagcacgt
    24061 ggtatcgatg atgtggcaac aatgtacaaa tacaatatta tcttagcaaa ttcagatggc
    24121 aacgaccaaa aagaagtcaa tgtattgaat aacttactgg ctaagcaagt ggacggcgtg
    24181 atcttcatgg gtcaccatat cacagacgaa atccgtggag aattttcacg ttcaaaaact
    24241 cctgttgtat tagctggctc tattgatcca gatgaacaag taggtagcgt aaacattgat
    24301 tatgtatccg caacaaaaga tgcagtaaac aaattggcaa aaagcggcaa taaaaaaatc
    24361 gcttttgtca gtggtgcgtt gatcgatccc atcaatggac aaaatcgtct gaaaggctat
    24421 aaagaagcat taagcgaaaa taacctacca tatagcgaag gattgatctt tgaagcacaa
    24481 tacaacttca aagatggtct atctctagtc gatcggatcc ataatagcgg tgcaacagct
    24541 gtctatgttt cagatgatga attagccatc ggtattttgg atggtttatt agaccgtggc
    24601 gtgaaagtac cggaagaatt cgaaatcatc acaagtaaca attcactact gacagaagta
    24661 gctcgtcctc gtttaacaag tatcacacaa ccattatacg atttaggggc ggtatctatg
    24721 cgcctattga cgaaaatgat gaataaagaa gaagtcgaag aaaaaacgat tatcttgcct
    24781 tatggaatcg aagaaaaagg atctacaaaa taataaaagg acaaccattc agaggttgtg
    24841 tgcctgccgt ttaactctgc gttacaagga gcaatttcaa aaaacagcat ctcatgtttg
    24901 atgaatattg tgactcgtga ttcggagttg gcaggagaac accgtttatt tgggaaaagg
    24961 ggttatgaca aaattttgtt ataatccttt ttttgtgtct taaaaaagag agaaagtggt
    25021 tgaaattaca tttatcgtat ataaaacaat ccgtgtatag atgctgcatt ttgttcacca
    25081 ccatcaaaaa aataagggac tgtgacaata ctattgtcac aatcccttat tactgtgtat
    25141 tctattaaat caatcatctt tctcatctga ttctttagtt gcttgattcg ctcttgcata
    25201 agctgaagcg gtgttccagt aatctgtata gttttcatcg gtaccgccaa cgccaaattt
    25261 aaaggcgctt ttcttcggtc catttttcgc ccatagcgat tcaactgttt ttcctggtgt
    25321 ttggatggat tttttattga cagtaacttt tccaggtgtt tgaccagtaa atccagatac
    25381 ttttttcttc atcacatcag atgataattc gaatttctca tcagtgccaa aaatgtcagg
    25441 ttttgcttgg taagcttgat tgatcagatt ggcaagataa ttagccgaac gtatccttgc
    25501 tttgctgtcc attccagtat tgtcatcgtg ccctgcccag ctactgatgg taatagacgg
    25561 agtagagaca attagccatg aatctcggta ttcattggta gaaccagttt ttccgaccca
    25621 atctgctttt cctagatttc cgtttaagct tgagatggca tctttgaatg gtgtagtgat
    25681 ttttgcattg atcacactac gcatcatgtc attcatgatc gatgccgttg cttccgaata
    25741 gatccggaca gagttgcttt cgtgtttata aattacattt cctgcgttat ctgtgatgga
    25801 atcgatgata tagccttctt catagacgcc gccgtttgct aaagcctgaa atccgttggt
    25861 ctgttgaagc gtcgtgacat ctactgtacc taaaggagca gattcaacgc cccaattgtc
    25921 atttgccggg tagttcatct ttgccaagta gtgctcgtaa gcatattgtt tcgatccacc
    25981 ggaattcaac acatcttgat ataagtgata agccgggata ttgttggacc attctagtga
    26041 ctcacggacg gtttggaagg tgttcgatcc ttcgttagta gcattgacga ttttctcgcc
    26101 agcattttct ccttcttgcc aagttgttgc ataatctgat acacgggatt ctgatccgat
    26161 aagccccatg tcgattgcag gtccataaac aagaactggt ttgattgatg agccagcttg
    26221 acgttctgta tcgaaggcat ggttattttg attctgactg taattccgtc cgccaacgaa
    26281 tccgtagatg cggccagttc tgttatccat caatacattt ccggtttcta cttgactgcc
    26341 agcaccatca tctaacatgt atccataatt ttcaacgcca ttttgcaatg cagcatagac
    26401 atctttatcg attgtcgaat ggattgtata tcctttattt tggatcgttt gctgtgcctt
    26461 ttgataataa gcgtcactga ccgatgaatc agacatatca gcgttgtctt tttcagccaa
    26521 ttgttgtgca atgattcttg ttgcttcatt catcacagta taatacaaga attctctgtc
    26581 agtctgttct gcgatttgtt gtggtagaaa gtcttttgta aggtcatagg cttttgcttc
    26641 ttcgtattgt tctttcgtaa tttggccttc acgatacata ctgaataaaa caaaatcttt
    26701 tctggcaagg ccggcagaaa gatcttcttt tagcgcgcct gtgttcgtgt atggactata
    26761 cgtgatcggg ctttggggta atccagcgat ataagcagct tgcggcagcg tcacatcttt
    26821 tgcatctaca ccaaagattc cttttgcagc ttcctggact ccagcaatgt tttgtccctt
    26881 attattacga ccaaatggtg agacattcaa atacgtagca atgatctcat cttttgaaaa
    26941 gtatttttct acttgtgcag aaagaatgat ctcgtttgct ttacgtttga atgttgtttc
    27001 atctgtaagg atctgctgtt tgactaattg ctgtgtcaaa gttgatccac cagaagagcc
    27061 aataccagta gcttcagata ctaatgctcg taaaacagct ttaggaacgt aaccttggtg
    27121 tttatcgaag tattcatcct ctgtgctgat aattgcagtt ttcaataaag gtgaaatctt
    27181 atcagatgaa atagtcgtgc gcatcagatc tgtctggatt tttgatatct ctgtattatc
    27241 tgcataaaca atctttgacg tttctgtaat gtttcctagt tctgtctgca gtgctttttt
    27301 agtcggcaat tgtgtgtctt cgacgagata ggcaaaatag ccagcgccta ttccaatacc
    27361 tagagctgcg aacatcaaaa gaagaacagt aataaaaaca gtcaatgatt gaaaaactct
    27421 aaaaataatc ttaggaacaa accatttttc tttttttctt ctattctgtt tttttcgagt
    27481 atttttgcgt ggcaaaaggg tcacctcaac taatggtttt atttcgctaa ttatagcaaa
    27541 taatagaaca aaaaaacaga caaggctgtt tttggcagga atttcttttt taaaagagtt
    27601 aaaacgtgag aaaatgatct ttattataaa agagttctta agcttttctt tagagaaaat
    27661 ttcagttact atggagaaca gggcaaagaa aaatcaatca ttttctttgt atatcatctt
    27721 accaatatat aggaattgtt agtaacaatt gcctttcaag gaggaatcca tccatgttat
    27781 taggctcaca cgtcagcatg agcggaaaga aaatgctgtt aggagcagca gaagaagcag
    27841 ccagttatgg atcttcgact tttatgatct atacaggcgc ccctcaaaac actagaagaa
    27901 aagccatcga agagatgaat attgatgccg gaaaagcgta catggcagaa aaaggtctaa
    27961 caaatatcgt cgttcatgcc ccttatatca ttaatttggg gaatacgatc aaaccagaaa
    28021 tgtttccttt tgccgtccaa tttctgagag aagagattgt tcgtgcggaa gctttaggcg
    28081 ctactcaaat tacacttcac ccaggtgctc atgtaggggc aggaacagaa gccggaattg
    28141 ctagaattat tgaaggcttg aatgaagttt tgacaaaaga acagacggca caaatcgctt
    28201 tggagacaat ggcaggtaaa ggtacggaaa tcggtcgaac atttgaggaa ttagcgcaaa
    28261 tcatcgatgg agtaaaattg aatgaaaaat tatccgttac ttttgacacc tgtcatacga
    28321 atgatgccgg ttataatatt aaagaagact tttcaggtgt aatggaagag tttgataaga
    28381 tcatcgggtt agatcggctt aaagtactcc atatcaatga ttctaaaaat ccgcaaggtt
    28441 cgcataaaga ccggcacgcc aatattggtt ttggaacaat cggattcgac acgctgaata
    28501 agatcgtcca tgatccaatg tttgacaata tttcgaaaat cttggaaact ccctatgtag
    28561 gcaaagataa aaagaaagct tacgcaccat atggaaaaga aatcgccatg ttcaaagcgc
    28621 aaacattcga tccagaagtg tttcctgagt tattagcaga agaagtgata ctctaagatt
    28681 ttctatctga cagcagcaaa aaaggaccag gcacattgcc ttgtcctttt ttgtttaaga
    28741 aacaaaggag tactttttgc agtctttttc atcatgcatc ttctcccccc tctttttaaa
    28801 tttagacaaa caaggtatac tggtagaaaa gtaaaaaaac gaaaagtttc acaagcaagt
    28861 ggcaaaacgt gattggaagg acgaaaagat gctgaacact ttaaaaccct tgatcaacca
    28921 actaaaaaag aaacatacat actttattct tggcatagcc ctattattta caattattcg
    28981 tttgtattta tatagtaaag caatctatgg aacagacatg tcggcaacct atgatgacca
    29041 gctgctgatt cgctatgctc aaaatatttt ggacggtaaa tggctagggg agtatacgac
    29101 tacaacactt tccaaaggaa tctcctacag cttattttta gtacttgcac ataaactgca
    29161 tctttcttat gcagttttgt tcggcatgtt cagtattttt gccagtatat tggttgcact
    29221 cgcgtttaaa ccgattgtga agaacaagta tcttctttta agtatctatt tttatttttt
    29281 gttttctccg attagtttta cacatgaata ttccactcga acatatcgta atgccctcgt
    29341 gattccggct gttgagatca ttatcgcttg tttattagct atttattacc gcaaatacgg
    29401 ttctagcaga aaattgctgc catggttttt agggctttct gtcgcttttc ctttcttttg
    29461 gttcattcgc gaagattcta tctggcttct tccttttact gtagtagctt tgggtatcag
    29521 tttcgtccag atcttgctag ggcaagactt ttctttcaaa gaagtaaaga agttaaaaaa
    29581 acgactcttt cttctctcga aacgggaatg gctgaaactt tcattgtttt tacttcctat
    29641 agttggcttt tccatcgtct atcaatggat cgaatataaa aatgagacaa catacggtat
    29701 tgcaaccatc aatgaccgtt ccagtggaga atttggacgt ttgatgaaac aactgatccg
    29761 aatagatgat gaaacgaact tgaataaaga aaacagtgag atatgggtct cacatgctgc
    29821 actaaataaa gcattagccg catctcctac attccatacc gtttctaccc gtattgacga
    29881 attatatacg actcacgcgt ggactcaagg tggaaaagta aaagaattac ccggagatat
    29941 catcttttgg gcattgcgag atgtggtaag cgaatctggt tattaccaaa acaatgcaaa
    30001 agaaaccaat gatttttgga aaaaagtcaa ccaagaatta gaagaagcct atcacaaggg
    30061 aacaatcaaa aagaaaaaag agttctatct gatgggatca ggagatggaa agacgatgag
    30121 tgatctgcca atcgtattcg atttccttca atcaggatac gcttatgcat ggcgatataa
    30181 agatttccat caaggaggaa attatagttt cggaacgcaa gaacaagtca aacaggctca
    30241 agaattatta aaccttccgc taatggagaa ttggatcgat agtaatgaac cgagaacacc
    30301 taatttccaa ttaacaaaat cagcaaaagt cgcgaatgtc atcataaaaa tttaccaagt
    30361 tctggctatt cccgtgctga ttgcttcaat agcagggata ttacttatga tactaggaac
    30421 cgtatttgca aaagctgatc gtgcctatta tagttcctct ttgattgtgg tcaccggatt
    30481 aatactgaca caattggttt ttcttttcgg tgtctcatgg ttttgttctt atgcgccaga
    30541 aaaaaaggac tattttttaa gtgtctacac tggtgcaggc gtgccattaa cgcaattcat
    30601 cgtagtaaca agcatgctag ttttcagtaa attaaatctg aaaaaagctt tatcttctaa
    30661 ataaaaagac ccttggtagc tagattttta acctaactat caagggtctt tgtgtggaaa
    30721 aatcagtttt tattcgattt cttctaccgt ttcctgcaaa agctgttcat attttttgtt
    30781 tcctttatat aaatcaccaa tcgtccatgc caacaggaga aggacaagaa caatgattac
    30841 ataagcgatg tgatcagcca atgctagttg agcggaagtg gcttgctcgc cgaagaaact
    30901 ttcgatctgt cctggtaatc ctcgtaagtt caagtaagtt agactaatca cagagaacca
    30961 gccaagaagt tttacgatga atgaattttt aaatcggcta cccatctccg cttggctgtt
    31021 ggtcatcatc agtaaaggaa tcatcgaaaa cggcaacgca aaagccaaga acacctggga
    31081 ttcattcatt aagttattca aagcggcatg ttcttcgatc gttccttttg tacttgtaaa
    31141 caaaacacaa atcaatacag gaatcacaga aagcaatcgt gtgaccagtc ttcttagcca
    31201 aatcgggata cgcatatgga tgaatccttc catgatgact tgaccggtca acgtaccagt
    31261 aatagtagag ttctggccag aagcaagaag tgctacagca aataaagtgg acaagatacc
    31321 agattttgct acagcaatca aaataccatt gctcatagct gatggatcag ataaagcttc
    31381 atacagacca aaaaaggaag gatcttggac agaaccggtt ttgaagacag cgacacccat
    31441 gatcaatagc agtgcattga ctagaaaagc cattgacaac tggatattag aatcccaagt
    31501 agaaaaacgt acagcttgtg ctacatcttc ttcgttttgg tgatcgatct tccgagtttg
    31561 tgaaactgct gaatgaagat ataagttatg cggcatgact gttgcaccaa taatccctaa
    31621 agctccagtc agcggagttt cgccgccgat gaccggtgag tctgagaatg tatgactgtt
    31681 agggataaag ccagcaaata aactgtgcca atctgggtta gacaagccaa cttgatagac
    31741 aaaaacgaat aaaatgacga aaattaagca gacaaccagt gcttcgatct tacgaaaccc
    31801 gacttttgtc agtagtaaga gaacgaaaac atctaataca gtaataaaga cggcaatcac
    31861 caatggaata tcaaaaagta agtagagggc gattgctgca ccaatgactt ctgcaatatc
    31921 tgttgccata atggctaatt cagtcaagat ccataaaatg acacctaatg tcttacttgt
    31981 gcgtgctcgg attgcctgtg ccaaatccat ttggctcacg attcctaatt ttgctgccat
    32041 atactgtaaa agcatagcaa tcagactaga catcaaaata actgacatca ataaatattg
    32101 gaaattttgt cctccggtga tcgaagtaga ccagttaccc gggtccatat acccaactgc
    32161 tactaacgca ccaggtccag agtaagcaag aagtgtttta aaaaaacttt tcccctttgg
    32221 tacatcaact gttccattta cttcagctaa agataaacca tttgtatgtt caataagtcg
    32281 atgcttatga aattgtttat tggattgatt attcaagaaa aaaccacctt tcctatttat
    32341 ctacgattac attctacacc tcaaaaagaa aaaattaaag aaaaagattc ggtacgccta
    32401 atttttttca tggcgcgtct tgctagatga cgaaagaaat tttgttctcc tctaaaaaaa
    32461 ccactatttt ttgcatgaaa ctaaagaata cgcctttctt ttttcaataa actttagtaa
    32521 aataagtcat tgagagcaat tcggaaatag aaaggagaga tttatatgtt atcaacaggt
    32581 attgtcgtac ttattgctat tattgctttg ctaatcggcg cagtaggtgg ctttttccta
    32641 gcgcgtaaat atatgaaaga ctatttagaa aaaaatcctc ccgttaatga ggacatgttg
    32701 cgatcaatga tgatgtcaat ggggcaaaaa ccatctgaga agaaaattcg ccagatgatg
    32761 cagcaaatga agaaccaagg gaaaaaatag gttctgaccc aacgactttt tacgggctga
    32821 ttttttcagt ccgtttttta tttcgtaatt tgttagacta ttcagattat tcagcaaaaa
    32881 agacaagcac agacaatcct aggctcttga taaagacaaa ggaggagtaa aatgtcgatt
    32941 tttagaaaat taggctggtt ttttcgtcag gaaaagaaac attatttaat tggggttttc
    33001 tcgctattcg cagtggcctt ggtacagtta gttcctccaa aagtgattgg gatcatcatt
    33061 gatgagatcg ccgataaaaa tttatcaata aagatcattt tcgggtggat cttcctattg
    33121 attatcgctg cttttttaca atatcttttt cgttatatct ggcggacgaa tatttgggga
    33181 agtgcagctc gattggagaa agaacttcgg cagcagttat tcaaacattt tacagaaatg
    33241 gacaatctct tttaccaaaa atatcggact ggggatttga tggctcacgc aacgaatgat
    33301 ttgaatgcga tccagaatgt agcaggagct ggtatcttga cctttgcaga ttcagtgatt
    33361 acgggcggaa caacgatcat tgcgatgatt ttgtttattg attggcgctt aacactgatt
    33421 gcgctgattc ctctgccttt gctggccgtc acttcacgag tgctggggtc aaaactccat
    33481 gatgcttttc gtgattcgca agaagctttt tctagtatca atgataagac acaagaaagt
    33541 atcactggga tcaaagtcat taaaacattt ggacaagaaa aagaagatct agcggatttt
    33601 gaagaaaaga ttgaagatgc aattattaaa aacaaacgag tcaatttttt agactcctta
    33661 tttgatccat tcattacctt gattatcggt ctgtcttatg ttgcaacaat tattttaggt
    33721 ggaaagtatg tcttggaagg cacgatctcg atcgggcaga tggtctcatt tattagttat
    33781 atcggtatgc ttgtttggcc gatgtttgcg attggtcgat tgttcaacgt attggaaaga
    33841 ggaaatgctt cttatgatcg cgtcaatgaa cttttgcatg aaaagacgca tatcgtggaa
    33901 caactgggtg cagtgcagac cccggcaaaa ggcgagctga atgtagctat ttcctctttt
    33961 aattatccga aagaagaatc accagcatta gaacaaatca agtttgcgat ccaagaagga
    34021 gaaacattag gtattgttgg gaaaactggt gcgggaaaaa cgacgatcat caaattactg
    34081 atgcgtgaat acgatgatta tcaagggaaa atccaatttg gcggacgttc gatcaaagaa
    34141 tattcattga atgctttatt aggatcaatc ggctatgtgc ctcaggatca cttcttgttt
    34201 tcgatgacca ttcgagataa tatccgtttt tctaatccaa aactttcaga agaagaagta
    34261 gagcatgcgg cttctttagc atttatcaac aatgaaatca aggaattacc aaaaggttat
    34321 gataccttag ttggagaacg tggagtctct ttatctggcg gacagaaaca aaggatttcg
    34381 attgctcgag cattgatcaa aaatcctgaa ttattaatat tagatgatgc actctctgca
    34441 gtagatgcca aaacagaaga agctatcttg cataatttaa aagaaataag aaaagagaaa
    34501 acaactatca ttgcagctca ccgtttaagt agcgtgatgc atgcaaaaga aatcattgtt
    34561 gtcgatcaag ggaaaatcat tgaacgagga acccatcatg agctgcttgc actaggcggc
    34621 tggtatgaac aaatgtggga gaaacagcaa ttagaagcga agatagaagg aggcgaggcc
    34681 tgatggatga aaattatcaa tcggaatgga caaaatcgat tccacttaaa gaacagaaaa
    34741 agatcatcaa acgactgatg aagttcgcca aaccttttag aagaacgttc atcgttgcta
    34801 tcttatttgc gtttgctttg tctgtgatca atgtcctatt gccaaggatc atccaaactt
    34861 ttatggatga tcatctggct aaacagtcgg ctacgacaca agttattttg ttttttgctg
    34921 gtatgtactt atttggagtc atagtaaaaa gtatcatttg gtttttccaa tggtatttgt
    34981 attccatggc ctcattgaag acctatcagt atattagggt aaaattattt gaaaagctgc
    35041 atacactagg tatgcgttat tttgatcaga caccggcagg atcaaccgtt tctcgagtga
    35101 cgaatgacac agaaacgcta tttgaatttt ggtacgtctt tttgatggta ttgactggga
    35161 tctttgcagt cgtttcttca ttccttgcca tgtttcaaat caatggagaa attgccttgt
    35221 ggactttggt gtttttgccg attttaggaa tcgtcatctg gtattaccag aaattcagtt
    35281 ctcgtattta ccgaaatatg cgggaaaaat taagtcagct gaacacgaaa ttgaatgaat
    35341 cgatttccgg catgcgtatt atccagcagt ttcgccaaga agctcgttta gctaaagaat
    35401 ttgaacaagt gaacaatgag tatttagaca cgcgttatgc gatgatcaaa acgaattcga
    35461 ttctgttaag tccgatcatc aattttctat atgcattggc gattgcgttg gtgttgactt
    35521 tgtttgggat cgatgcgttg cattctcccg tagaagttgg actgatctat gcatttacga
    35581 cctatgtcca gggatttttt aatccaatgt ctcaaatgat ggactttttg agcatcttca
    35641 cagatgggat ggttgctggt agtcgtatct tgaagattat ggatacggaa gaatatgcac
    35701 cacaacaaaa ccctggagca gatcaaatga ttacttcagg taagattgag tttcgcaatg
    35761 taagcttttc ttatgatgga gagcacaatg tattaaacaa tatctctttt gttgctaatc
    35821 cgggagagac cgttgcatta gtgggacaca ccggaagcgg aaaaagctcg atcatcaacg
    35881 tattgatgcg gttttacgaa ttttatgaag gtcagatatt gattgatgat catgacattc
    35941 gagaatatcc aatggaagag ttacgtaaga aaatggggct ggtcttgcaa gatgctttct
    36001 tgttttatgg ggatatcgca ggaaatattc ggatgatgaa tccagctatc acagacgaac
    36061 agatacgcca tgcggctgag tttgttcaag caaacaaatt catcgatgaa ttaccaaaag
    36121 gatatcactc aaaagtgatc gaacatggtg ccagctattc tagtggacaa cgacagctga
    36181 tcacttttgc gcgaacaatc gtgactgatc ctaaaattct agtattggat gaagcaacag
    36241 caaatatcga tactgaaaca gaaggattga tccaagaagg attggcaaaa atgcgtcaag
    36301 gacggacaac gattgcgatt gcccatcggc tgtcaacgat tcgagatgca gaattgattt
    36361 tagttttaga caaaggtcat atagtagaac gcgggaatca tgaaacactt ctagcgcaaa
    36421 atggtttgta tgcagatatg tacaaactgc aaagcagtgg tatataaaag atgttgtgac
    36481 agtagaattt tgacctaagc actagagtga aaataaaaca tagcttctca tatttttcat
    36541 ctgtgagagt tagtgtcgta gtcaccagat ttaaaaaaag attcgacagc tagtcagaag
    36601 tgcctaatag ccactaagaa agcgttgaca aaagcatttg ctttcgataa tataaagaaa
    36661 acgatacaac ttggatagtg attgcctgat gcaagctaaa cctgatgagt ctcccatggt
    36721 ttcatggacg gctttttggg tttttctttt tgttttggat acagccctat acatcatgga
    36781 aaggagcaaa acatgctgat tgagaaagta ctgaataaca acgtcgtaat aaccagggat
    36841 gaaagaaatc aggaaatgat cgtgatggga aaaggtttgg cattcaaaaa gaaagtgggt
    36901 gacccgattt ttgactcatg catcgacaaa aaatttcagt tgacaaatga cgggctttca
    36961 caacagttcc aagaattggc acaagcgatt cctcttgagt acttagaaat ttcttgtgaa
    37021 atcattgaat atacaaaaga ggctctacaa gtccagttga atgattctgt gtatattgca
    37081 ttgacggatc atttgtatac ggctatcgaa cgtcacaaaa tgggaatatt tgtaccaaat
    37141 gtattgctgt atgatatcaa acaactattt cctaaagagt atgccatcgg gaaaaaaaca
    37201 gtgaagaaaa tctcggataa ataccacatc aagttatcag aagatgaagc cggatttatc
    37261 gcattgcatt tagtcaatgc acaaggcatt caaagccagc aagacaatac ctacctgttt
    37321 actataacaa tacaggatat tctaaatatc gtccgctatt actataagat tacatttgat
    37381 gaagattcag tccatttttt tcgattcgtc acacacttac gtttttttct gacacgcgtc
    37441 ctagatggag aaaaatcaga agtgggagaa gtttctgagg aattgtttca ggttattcaa
    37501 aaaaaatata aggatacgtt tggttgcgtt gagaaaatag cagacttttt agccgagacg
    37561 ttcaactacc agatgtccac ggacgaaaaa atgtatttaa cgatccatac tgcgcgttta
    37621 gtgcatgaga atcgttgtaa ataaaaaaag gaggataaat taacaagaac gtatgaaata
    37681 agggtagtga cattcagttg gctaaacctt ccactaataa attggaggga atagaaatgg
    37741 gaaaatacca agaattagcg agaaaaatcg tagaaaatgt cggcgggaag gaaaatatca
    37801 atggtttgac acattgtatc acaaggcttc gtttcaaatt aaaaaacgaa gaaaaagcaa
    37861 atgatgagat cttgaaaaat atggacggta ttgtaacggt aatgcgagcg ggagggcagt
    37921 atcaagttgt cattgggaat catgtgccag tcgtgtttga agaggttata aaagcaggaa
    37981 accttacttt tgatgaggct gtttcaacag aaaaaatgag accgtttgat atgcttattg
    38041 atggaatatc gggctgtttc cagccattcc ttgctatcct agctgctggc gggatgattc
    38101 gtggactgac agcattcctt gtcttcttag gcgcgtttga ccgcggttct ggcacatttg
    38161 ttatgtttga taatatcggt gattctgtat tccaatttat gcctgttatt atcggtttaa
    38221 cagctgcccg taaatttaaa gtaaatgaat tcgtagggat gttgcttggc gcagcattaa
    38281 tgaatcctag cttgtcgctg gaagctttga gtggtgcagc agaagcacca ctaacgacca
    38341 tattttctgg cactattttt gaagcaccta tttatcaaac agtattcggc attccctgga
    38401 ttgcgcgtaa ctacgcttct tctgtcattc ccattatctt tattgtgttg ttagctagcc
    38461 aaattcagaa accaattaaa aagttagtac ctgagatgat cgcgaatttc ttcgttccat
    38521 tcttcaccgt tcttattaca atgcctttag gttttttact cgttggacca gtattcacat
    38581 tcgcaactga tattttaatg gctggatttg aaacactttt agcactttcg ccagttattt
    38641 atggagcaat cgtaggcttc ttctggcaaa ttctggtgat gtttggtctc cattgggcaa
    38701 tcgtaccaat gggattgatg caattttctg tgaatggttg gcaaaatatt atgacacctg
    38761 ttgcagtagt gtcttttgga caaactgcag cacttaccgc actctacttt aagcttagaa
    38821 atccaaaaga caaagcaatt gcaataccag ccattgtttc tggtattgtg gggattacag
    38881 agccagctat ttatgggttt acattaccac gtaaaaaaat atttattttt acctgtgtcg
    38941 gtggtgcgtt agggggcgcg tatagtgggt taatgaattt aacttcttgg aatcaaggtg
    39001 gactaggcat ctttacaatt cccaactata ttagaccaga tggtgattta acagatgtga
    39061 ttaatgtatt gattgggatc gccattgcga tggtggtatc ctttacgctg acttttttct
    39121 tttggaagga tgaagcaggt gaaacagatg atatacagaa aaaatcaggt aaagaaattg
    39181 taaaaacacc gatacaagga caaatcgctc cactaaatgc agcaaaggat gcagcttttg
    39241 cacaaggaac actaggtcga ggaatcttga tctaccctga aaaaggagaa gtacgtgccc
    39301 cttttgacgg aacagtcatg accctgttcc cgacgaaaca ggcaattgga atggtttctg
    39361 aaacagggct ggaattgctg attcatgtcg gattggatac tgtgcagttg gaagggaaat
    39421 attttgaaag cttagtgcag caaggataaa gagtgaaaca aggcgatctg ttgctacgct
    39481 tcgacaaaaa gaaaatcgaa aaggaaggat acagtttaga aacacctgtg atcgtcacca
    39541 attacacgga ttatttggat attttggaaa accaagggga gacggtcggg ccagacgatg
    39601 cacttatcac cgcactgacc tgaacggtta ggtgaagaat ggactaggct taactattct
    39661 ttttattcca cttctttatt ttcaaaattg aaaggctctt tcatgatggc tgagctgata
    39721 gggcgtttat cgaatttttg accgacagaa attagatgga ctaaattctg ttgataattt
    39781 tctgcaaaaa cacaactata taacacgtct agaagataac aaattgatgt attgatcgta
    39841 aaattaccaa tttttgaata cagtcgctcg cgtgtcgtaa gtcgcaaagc ggctgtactc
    39901 attgcagata gcgttgaatc accgatactg gtcaaagcta aaattggaac atgattttgt
    39961 ttcaatattt ctgcggtacg aaggatcaca ttgttttcac ccgtataaga aatcagaatc
    40021 ccgcacatat cactcgtgca attgtacgct tcatagaatg attcaccaaa agtggtgaca
    40081 atcgtgacat ccattttgat gcgcttcatt ttcagcatga aatcttgaga aatcaaagta
    40141 ttcgagttac tggcgaaaat cacgattttt tttgcttgaa gcattagttg tttggctttt
    40201 tgcagttggt catgatgaat gagagaaagt gtatcatgaa tcgtcatctg ttctaaagaa
    40261 gccattttat ttgcgatcgt cataataccg tctgtggtgg aaaaaggaag attcgcatct
    40321 acgtcttgaa aattcccttc aagataggct gtttcagcta aaaaagcatt acgaaaactg
    40381 acccagccat caaaacccat tttttttgct acacggatga gtgtagaggg gtggacataa
    40441 catcgctcag caatcgcttg gatggtcatt tcgccaagtg ctggagaatc gcttaagaga
    40501 aactggatca cttcattttc tgaaggagaa aaggagattt ctttgatttt ttcacgtaat
    40561 aacatgtaga taccttcttc ttattttttt acgtaaatta taactttttt gaaaatgatt
    40621 tgtaaacgga tttatactat ataacttaaa atagacattt tttgacaaga tatttacaaa
    40681 aatccactag aaaacagtaa attttgtaaa tgttactgga aagaaacaga tttctattgt
    40741 ttgttttgtt tacaaaaaag ataatgaaag tgtaaaaaag taaaggagtg agaacatggc
    40801 aaaaggaatc aaaatcgcta cgattggtgg aggcagcagt tacacccccg agttgatgga
    40861 aggatttatc aaaagatatg aggaattacc gatacgagaa atctggctcg tagatgtaga
    40921 agaaggaaaa gaaaagcttg agatcgttag tcagatgtct cagcgtatgt gggatgcttc
    40981 tccgtatgaa gtcaagatct atgcaactct ggatcgggaa gaagcattga aagatgcgga
    41041 ttttgttacg actcagtttc gtgtcggtca attagatgca cgaatcaaag acgagcggat
    41101 ccctagttat tatgggatga ttgggcaaga aacaaatggt gctggcggga tattcaaagc
    41161 ttttcgtacc gttccagtcg ttttggcaat cgttgaggac atgaagcgtt tatgtccaaa
    41221 tgcttggctg atcaatttcg cgaacccaag tgggatggtg acagaagcag ttatcagata
    41281 tggcaaatgg gataaagtga ttggattatg caatgtgcca gtgatggcga tgatgacaga
    41341 accagcaatg cttggcaaga aaaaagaaga gctgatctac aagtttgccg gtctaaatca
    41401 tttccattgg cacaaagtag cagataataa aggaaatgac cgcacggcag aattgattga
    41461 tcgtttatac gatgaagaga atggattacc gaaaaatatc tttgatatcc cgtttttcaa
    41521 agaacaatta aaacaaatga acatgatccc ttgtggctac caccgctatt actatcgtga
    41581 agaagaaatg ctggaacatg ctttagaaga atatcaaacg attggtacaa gagcgcagca
    41641 agtgaaagaa acagaagcag agctatttga attatacaaa gatccagaat tagaccataa
    41701 acctgaacaa ttgcaaaaac gaggtggcgc ttattattca gacgctgcct gtgaaacgat
    41761 tgcttcaatc tatggaaata aagaaacaca gatcgtggta tctacaaaga atgatggagc
    41821 tgttcctgac ctgccggcag attgtgtagt agaagtcact gcctatgttg gcgcacaagg
    41881 agcgagaaat gtagcgtttg gttctcttcc tgctgctgaa agaggctggt tgcaagtaat
    41941 gaagaatatg gaattgctga cgatcgaagc agctgtgact ggtgattatg ggacagcttt
    42001 acaggcgttt acgatcaatc cacttatacg atcaggaaag acagcaaaac ggatcatgga
    42061 tgagttgttt attgcacacc agcagtattt accgcaattc aaggagacaa tcagccgatt
    42121 aaaagaagaa ggaatcgaag ttcaagatga actggcaaga gaattatcag gtaatacaca
    42181 tataatggag gaagtataat gggattcaga aaagattttt tatggggcgg tgctacagca
    42241 gccaatcaat gtgagggcgg ttatgatgaa ggtggacgcg gactagcaaa cgtagatgtt
    42301 gtgccaatcg gaaaagaccg ttttcctgtt atcaccggaa agaaaaaaat gtttgaattt
    42361 gatgaggatc atttttatcc agcaaaaatt gcaatcgata tgtatcatcg ttataaagaa
    42421 gatattgctt tgtttgcaga aatggggttc aagacttatc gaatgtccat cgcctggagt
    42481 cgtatttttc caatggggga tgagaaagag ccgaatgaag ctggcttgaa attttatgag
    42541 gatgccttta aagaatgcca aaagcacgga attgagccac ttgtgacgat tacgcatttt
    42601 gattgtccaa tgcatttgat caaagaatat ggtgcgtggc gttccagaga actcgttggt
    42661 ttttatgaaa atctgtgtcg agtcatcttc aatcgctata aaggacttgt caaatattgg
    42721 ctgacattca atgagatcaa tatgatcctt catgcaccat tcatgggcgc agggctgtat
    42781 tttgaaaaag gagaaaatga agaacaaatc aaatatcaag cggcacatca tgagttggtt
    42841 gcaagtgcca tcgcaacgaa gattgctcat gaagtagatc cggagaacaa agtaggctgt
    42901 atgctggcag caggagcata ttatccatac acttgcaatc ctgaagatgt ttgggcttct
    42961 agaaaatcag atcgagaaaa ttatttcttc attgatgtcc agtcacgagg agaatatccc
    43021 gcttatgcat tgaaagaaat ggagcgaaat ggcattcaga tcgaaatgga accaggggat
    43081 gccgcattgc tgaaagaaca tactgttgat tttatctctt tttcttatta tgcttcccga
    43141 gtttcgacta ccgacaacga actcttggaa cagactgcag gaaatatctt tgcttctgtc
    43201 aaaaatccat atctgcaagc aagtgaatgg gggtggcaaa ttgatccatt aggcttgaga
    43261 ataacgatga atgatattta tgatcgttat caaaaaccat tgtttattgt agaaaacggc
    43321 ttaggtgcag tcgatacgcc agatgaaaat ggttatgtgg aagatgatta ccgaatcgat
    43381 tacctggcag cgcatatcca ggcgatgaag gatgcagtag aactagacgg agtcgatcta
    43441 ttaggctata cgacttgggg atgtattgat ttagtatcag ctggtaccgg tgagatgaag
    43501 aaaaggtacg gattcattta tgtcgatcgt gataaccaag gaaatggcac attagcccgt
    43561 tcaaagaaaa aatcattcaa ctggtataaa aaagtaattg attcaaatgg agaaaatctt
    43621 tcgaacgatt gatcaatgat ttataaaagt ctattgtttt tcagcggatt tttcgagtat
    43681 aataaagcta ttcgagaaac gcaagcagaa caatagactt tttttcgcat tggctgtaaa
    43741 gtatgcttac ttgattaagt aaaggagaat ctacatatgt atgatgtaat cgttattggc
    43801 gcaggtcctg ctgggatgac tgctgcttta tatgcttcac gttcaaactt atccgtattg
    43861 atgatcgaac aaggtgcccc tggcggccaa atgaacaata cggcagaaat cgaaaattat
    43921 cctggattcg attcgatcat gggccccgat ctagcttata agatgtatga aagtgtctca
    43981 agatttggga cagaaaatgc ttatggaatc gttcaagata tcaaggatca cggcagccat
    44041 aaagaagtca tctgtgaaga taaaagttac gaaggaaaaa cagtcattat cgcaacagga
    44101 tgtatccacc gtaaattagg cgtacctggc gaggaagaat ttgctggacg aggcgtttct
    44161 tactgtgcag tctgtgatgg tgcgtttttc cgtaacaaac gtctagtagt catcgggggt
    44221 ggggactcag cagtagaaga agccatctat ttgacacaat ttgcttctga agtagtgatc
    44281 gtccaccgta gagatgaatt acgtgcacaa aagatcatcc aagaccgtgc atttgcaaat
    44341 gaaaaaattt cctttatgtg ggatacagtc gttgacgaaa tcgttggaaa cgaaatggta
    44401 gtgacaggtg tgaaagcacg taatgtcaaa accggcaatg aatttgattt agcagcagac
    44461 ggagtattca tctatgttgg actggatcca ttaactgcac cttttagaga agcaggtttg
    44521 acgaacgaag ctggctggat tccaacagac aacgaaatga aaacgaatat gccaggcgtt
    44581 tttgccatcg gagatgttcg tgaaaaagat ttgcgacaaa tcactacagc tgttggtgac
    44641 ggcggtattg ctggacaaca agtgtataaa tacttggagt ctttagaaga aacaacagca
    44701 taagtttaaa aagagtagaa gaacgggttc aattgttctt ttactctttt ttttcgcgtg
    44761 aaatttactg aatctgattt atgcgaacac gtccaacacc ttttgataaa agaatccttt
    44821 cttgatttaa gcgttttttg gtcctcatac tttcatatct aataagtgaa tgctatactt
    44881 attaagaacc atatttcaga aagaggtgtt attttcatgt cttgggaaca agtgtatgaa
    44941 caatgggtac atgaagaaaa tttagaagaa aacttaaaaa aacaattaaa tgatctgggt
    45001 gaagatcctg aaaaacttga agatgctttt tatgcaccgt tggaattcgg tactgcaggt
    45061 atgcggggaa tcttaggacc tgggatcaat cgaatgaaca tctatacggt aagacaagca
    45121 acagaaggac tagcacgttt catggataca caaggtgaag aaacaaaacg ccgaggtgtc
    45181 gctatcgctt atgactcacg ccatcagtca ccagaatttg caatggaagc agccaaaaca
    45241 ctagcacatc acaatatccc gtcttatgta ttcgaaagtc tgcgtccaac accagagctt
    45301 tcttttgcag ttcgtcattt gaagacgttt gcgggaatca tggtaaccgc atctcacaac
    45361 ccagcggctt acaatggata taaagtctac ggagaagatg gcggacaaat gcctcctgca
    45421 gacgcagatg cattgacgaa atatgtccgt gaagtcagca atccgctaaa agtcgaagta
    45481 ttatctgacg aagaagctaa acatagcggg ttgatcacga tcatcggaga agaagtggac
    45541 gctgcttatc tagaagaaat caaagcagtg acgattgatc gtgaattggt tgaaacaatg
    45601 gggaaagatt tgaaacttgt gtacacgcca cttcatggaa cagggaaaat gttgggcgaa
    45661 cgtgcgttga aacaagctgg attcgaacaa ttcgtactag ttcccgaaca agctgtggca
    45721 gatccagatt tcactacggt caaatcgcca aatccagaag aacattcagc ttttgaatat
    45781 gctatacgac ttggagaaaa agaaggagct gacttgctga ttgcaacaga tcctgatgca
    45841 gaccgtttag gcgcagcggt tcgtttgcca gatggttctt atgaagtatt gactgggaac
    45901 caaatcggag cattgtttgc tcaatatatt ttggaagcac atcaatcaag aggcacttta
    45961 ccagaaaacg cagcggtatt gaaatcaatc gtttccagcg aattgcctac agcaattgcg
    46021 gaacactacg gtgctaccat gttcaatgtg ttgacagggt ttaaattcat tgctgaaaaa
    46081 atccaacaat ttgaagaaga ccattcacat acttttatgt ttggattcga agaaagttat
    46141 ggttatttag ttaaaccttt tgttcgcgat aaagacgcga tccaagcatt gcttttatta
    46201 gcagaagtag cagcttacta taaaaaacaa ggcaaaacgt tgtatgacgg cttgcaaacg
    46261 atttttgaaa cctatggcta tttcgcagaa aaaacgattt ctgtgacaat gagcggacaa
    46321 gaaggttctg cgaaaatctc tgctttgatg gaaaaattcc gtaaagaagc accgacagaa
    46381 tttgccggag caaaagttat tcaaacagaa gactttaaag aattgacgag aacagaccgt
    46441 gaaggaaacg tagaaaaact aacaacaccg ccatccgacg tattgaagta tacattggaa
    46501 gaaaatggct ggatcgctat ccgcccttca ggaactgagc cgaaaatcaa gttttatatt
    46561 ggtgtaaaag gaagctctac agaagacgca gccgaaaaag tagcctctta tgaagcgatt
    46621 atcaaaaaga tgacagaaga ataaaaaact tgagactgat ggaaaaagtg gtaaacttta
    46681 gaagtcagtc ttttttcaag ttggaggtga atggattgcc agacacgcaa aaatcaaaag
    46741 tagagaaagt cagtcaatta ttcaaaatgt tgagtgatcc cactcgtctt aaaattctgc
    46801 tatatctgaa agacggggaa caaaatgtga cagcaatcac ccaagcagtg gaaatggagc
    46861 agtctgctgt atcgcatcaa ctacgtttat taagagaaaa tcatgtcgtc aagtctcatc
    46921 gcgagggaaa agcgattttg tatagtcttg atgattctca tgtactggat attttgaacc
    46981 agacactcaa acatgtggaa catcaataac gataggtgaa aatagataaa cgctggagtg
    47041 tgacaacgaa gaaatttcgt tgtcacactc cagtgttttt taagaaaaag acaaaaatga
    47101 ttaatcgctt ttttctgttg tttcagttcc ataataacta tgatcttcta ggtctaaagc
    47161 attcaaaata agcgaagccg tttcttcaat agataaagat gccacattga tcactacaca
    47221 tcctagtttt tcataaagat cattcgcaaa atcgagttca gctctaattt tttcgatatc
    47281 ggaataagca gtatcagggt ttaatccgta agagcgcatc cgttctttac ggatattatt
    47341 taaaatatct gggttattcg ttagtcccac gattttttta ggatcgattt cccacagctg
    47401 tttgggaata tgtgcttggg gaatcaaagg taaattagca acttttaaat ttttatttgc
    47461 taaaaacaag ctcaaaggcg ttttggaagt tcgggatacg cctagcaaaa cgacatctgc
    47521 ttctaaaaaa ccacgaggat ctttcccatc atcgtatttt acagcaaatt ccattgcttt
    47581 gatccgtttg aaatagttct cattcaataa atggagggca ccaggttgcc gaattggctt
    47641 gataccagtt aaacgttcaa tttctgatat cggtggcgtc atcacatcga aactaaataa
    47701 ttgatgttct tcacaaaaag aacgtgttat ctcgatcagt tcttgattga ttaatgtatg
    47761 caggacaagt gctttttctt ctaatgcatc ttgcaatgcc tgccttaatg ttttttcatc
    47821 tgtcacgaac gttctgcgga ataggttgaa ctcaacggta ggatactgag ccatagtagc
    47881 ttgcgctagt tttgtcgcag tttctccagc agagtcggag atgacaaaaa aagtaacgat
    47941 ttctgtagaa tcggaagaca tggataaaac ctcacttgca ttttttttat gtttattata
    48001 ccatactcta gaatgcgtac ttcgtaatca ttttgatttg gaggaataag tcatgaaaaa
    48061 acagacattg atcgaacaat cattagaaac attgaaaaat aacggtttta aatatactaa
    48121 aaaaagagaa gcattgttaa cttatttagt gaagcgtaac cgctacgtat ctgctaaaga
    48181 agtttttgac tatatgaatc aggaattcaa aggggtaagt tatgatacga tttaccggaa
    48241 tctccatgat tttgcagaga tcgatttact ggaagaaacc gatttaaatg gtgaaatgaa
    48301 gtttcgtttt cattgctgtc agggggaaat cggccatcac catcatttta tctgtacagt
    48361 gtgcggaaca acgaaagaaa tccatatgtg tccaatgaat tatttcgaag aacagctagg
    48421 tggatgcacg atcgaagggc atagattcga gattttcgga agatgtgaaa attgtcaata
    48481 aggatttaaa taaaataaca tttgataatt taaaaaaaaa gcaagatttc cttgacggtc
    48541 aaaacagcat tagatataat atttacagga cagtcttgtt ttttgagata tatttcaata
    48601 acaattacgg ttacttttta agctcggagg gagggaatta acatgtcaaa aacagtcgtt
    48661 cgcaaaaacg aatcacttga cgatgctctt cgtcgcttca aacgttccgt gtcaaaagcg
    48721 ggtactttac aagaatctcg taaacgtgaa ttctacgaaa aaccaagtgt aagacgcaag
    48781 aaaaaatctg aagcagctag aaaacgcaaa aaattctagt tctgtgatga attggagttg
    48841 gtagtgtgtc actactaagt agattaaacg atgacatgaa agcagcgatg aaagcgaaag
    48901 ataaggaatc tttacaagtc atccgaatga tcaagtcatc tatacaaaac gagcagatta
    48961 aagaaggtca cgacttgaca gaagaagaag aactaacggt gttgtctcgc gaaatgaaac
    49021 agcgacgtga ttctttgcat gagtttgaag aagcaggacg tgacgattta gctgaaaaag
    49081 taaaaagtga aattgtaata gtcgaaaaat atatgccgga acaactttcc gacgaagaaa
    49141 ttcgacaact tgttcaagaa gcaatcactc aaactggtgc ttcatcaatg aaagaatttg
    49201 gcaaagttat gggtgcaatt atgcctaaag tcaaaggaaa agcagatgga aaccaagtga
    49261 atgcgattgt gaaagaacta ttacaatctt aattttatca tttaaactgc ggacagtgat
    49321 tgtccgcagt tttttgtgtt cgtaaaaaaa gaactaaaaa acagctagaa gaaagaataa
    49381 gattctttct tctagctg
//
LOCUS       DACDLM010000014        49161 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.014, whole genome shotgun sequence.
ACCESSION   DACDLM010000014 DACDLM010000000
VERSION     DACDLM010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49161
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.014"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            212..604
                     /locus_tag="IV356_000835"
     CDS             212..604
                     /locus_tag="IV356_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP9014544.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="IV356_000836"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="IV356_000836"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HAP9014545.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="IV356_000837"
     CDS             3165..4775
                     /locus_tag="IV356_000837"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HAP9014546.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="IV356_000838"
     CDS             5067..5936
                     /locus_tag="IV356_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HAP9014547.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="IV356_000839"
     CDS             6101..7372
                     /locus_tag="IV356_000839"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAP9014548.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /locus_tag="IV356_000840"
     CDS             7369..8664
                     /locus_tag="IV356_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HAP9014549.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="IV356_000841"
     CDS             8763..9026
                     /locus_tag="IV356_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HAP9014550.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="IV356_000842"
     CDS             9471..9920
                     /locus_tag="IV356_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP9014551.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="IV356_000843"
     CDS             9977..11395
                     /locus_tag="IV356_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP9014552.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSISTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="IV356_000844"
     CDS             11395..12255
                     /locus_tag="IV356_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HAP9014553.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="IV356_000845"
     CDS             12429..13202
                     /locus_tag="IV356_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP9014554.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="IV356_000846"
     CDS             13349..13714
                     /locus_tag="IV356_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HAP9014555.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="IV356_000847"
     CDS             complement(13862..15070)
                     /locus_tag="IV356_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP9014556.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="IV356_000848"
     CDS             complement(15089..15367)
                     /locus_tag="IV356_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014557.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15560..16216
                     /locus_tag="IV356_000849"
     CDS             15560..16216
                     /locus_tag="IV356_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAP9014558.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            complement(16658..17455)
                     /locus_tag="IV356_000850"
     CDS             complement(16658..17455)
                     /locus_tag="IV356_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HAP9014559.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="IV356_000851"
     CDS             complement(17452..18636)
                     /locus_tag="IV356_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAP9014560.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="IV356_000852"
     CDS             complement(18661..19908)
                     /locus_tag="IV356_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virion core protein"
                     /protein_id="HAP9014561.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="IV356_000853"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="IV356_000853"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HAP9014562.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="IV356_000854"
     CDS             21888..22202
                     /locus_tag="IV356_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HAP9014563.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="IV356_000855"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="IV356_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HAP9014564.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="IV356_000856"
     CDS             22887..23531
                     /locus_tag="IV356_000856"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HAP9014565.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="IV356_000857"
     CDS             23546..23875
                     /locus_tag="IV356_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014566.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="IV356_000858"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="IV356_000858"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HAP9014567.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="IV356_000859"
     CDS             24863..25687
                     /locus_tag="IV356_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HAP9014568.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="IV356_000860"
     CDS             25680..26027
                     /locus_tag="IV356_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HAP9014569.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="IV356_000861"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="IV356_000861"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HAP9014570.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="IV356_000862"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="IV356_000862"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HAP9014571.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="IV356_000863"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="IV356_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HAP9014572.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="IV356_000864"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="IV356_000864"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HAP9014573.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31684..32451
                     /locus_tag="IV356_000865"
     CDS             31684..32451
                     /locus_tag="IV356_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9014574.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="IV356_000866"
     CDS             32441..34483
                     /locus_tag="IV356_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9014575.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="IV356_000867"
     CDS             34764..34913
                     /locus_tag="IV356_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HAP9014576.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="IV356_000868"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="IV356_000868"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HAP9014577.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="IV356_000869"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="IV356_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HAP9014578.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="IV356_000870"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="IV356_000870"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HAP9014579.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            37921..39189
                     /gene="dltD"
                     /locus_tag="IV356_000871"
     CDS             37921..39189
                     /gene="dltD"
                     /locus_tag="IV356_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HAP9014580.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39330..40412
                     /locus_tag="IV356_000872"
     CDS             39330..40412
                     /locus_tag="IV356_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HAP9014581.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40412..41215
                     /locus_tag="IV356_000873"
     CDS             40412..41215
                     /locus_tag="IV356_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAP9014582.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41285..42025
                     /locus_tag="IV356_000874"
     CDS             41285..42025
                     /locus_tag="IV356_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAP9014583.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42036..43040
                     /locus_tag="IV356_000875"
     CDS             42036..43040
                     /locus_tag="IV356_000875"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HAP9014584.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43085..44929)
                     /locus_tag="IV356_000876"
     CDS             complement(43085..44929)
                     /locus_tag="IV356_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014585.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
     gene            45141..45659
                     /locus_tag="IV356_000877"
     CDS             45141..45659
                     /locus_tag="IV356_000877"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAP9014586.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            45787..46470
                     /locus_tag="IV356_000878"
     CDS             45787..46470
                     /locus_tag="IV356_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HAP9014587.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            46779..46852
                     /locus_tag="IV356_000879"
     tRNA            46779..46852
                     /locus_tag="IV356_000879"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:46813..46815,aa:Arg,seq:tct)
     gene            47011..47370
                     /locus_tag="IV356_000880"
     CDS             47011..47370
                     /locus_tag="IV356_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HAP9014588.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            47493..49124
                     /locus_tag="IV356_000881"
     CDS             47493..49124
                     /locus_tag="IV356_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HAP9014589.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
BASE COUNT        15807 a         8509 c        10224 g        14621 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgattt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt agtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtat ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcggaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcattcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg agcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    39241 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    39301 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    39361 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    39421 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    39481 aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt
    39541 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    39601 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    39661 acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt
    39721 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    39781 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    39841 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    39901 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    39961 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    40021 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    40081 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    40141 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    40201 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    40261 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    40321 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    40381 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    40441 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    40501 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    40561 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    40621 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    40681 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    40741 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    40801 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    40861 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    40921 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    40981 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    41041 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    41101 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    41161 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    41221 aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg
    41281 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    41341 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    41401 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    41461 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    41521 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    41581 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    41641 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    41701 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    41761 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    41821 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    41881 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    41941 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    42001 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    42061 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    42121 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    42181 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    42241 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    42301 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    42361 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    42421 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    42481 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    42541 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    42601 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    42661 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    42721 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    42781 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    42841 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    42901 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    42961 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    43021 tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta
    43081 ttttttatac aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag
    43141 tatctttttc ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc atcatcatta
    43201 agtcaaaacg ttcctgatca tctaattctt ctgtgatgcc tcgactaaat aggtttgtat
    43261 cgtaatgtgc actatgttcg caacaaatga cgaaatgttc ctcttgttcg tgtatcgaca
    43321 aataaatttt tcgatacagt ggattttcga tggcatgagt ttctctaaag gaatgctcta
    43381 aagcgtggat caaaagttga gccagatcgt catcgttgat aggaagttct tcgggaagat
    43441 ctgcttggaa ggttatctga atattccgtt tggcagctaa cttctggtaa cgcgctaaga
    43501 taagatttgt cacctggtgg ttgcaaaaag aacacagcat ttcgaaattt tttgcttctt
    43561 ctaatatctt ttccacatag tttttagctt ttgtttggtc cgtatgcatt aaatcttgca
    43621 gattctccat ctcttggaca aattccaggc gaagtgtatt tacttcttgg atatgctgtc
    43681 gaagctgctc ataatgttgc tccaacaaat catttttgat ttttaagaaa tctacttgtc
    43741 tccgatcttt gtcggtattt aagatgtgat cgattagatt gtagctgata ataacgatta
    43801 gaatgataat atataaaatc gtagaccaat tgatcgttgt ttgatagata cctaatgccg
    43861 tttggatgta aatcaagcaa tggataatgg ctaccaagac gatccaaggt gtacaagcta
    43921 cataaaaacg gttattctta tatgcttcgc caatgcatgc aagtgaagtg actaaagtgc
    43981 ttataacact agcaatatta gcaatcggca ttaattcagg aagttctgca ggagtaaaag
    44041 ttgcataaag cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa attccgtacc
    44101 attttttata gtaaaacatt cggctccaat agtagcagat gatgaaagct gacgttaaga
    44161 taataaataa atgagataaa aaagaatgaa cgaatggttc aaaaagaata ccacttaaaa
    44221 tatcttctga tacagcttca aatcctaatg ccaaagcaaa gcaacttaag agaataagtg
    44281 agtattcaag acgtttttgt ttatacatca agtagatcgt atagaaaaag gtccctatag
    44341 cgataaaaac agcgattatc atcgtcaata cttgcggcac tgattgtgaa taaataaaac
    44401 taatcaatgg tccagttgtt cctagataaa ctttcggtgg cagtccagca tagttctgat
    44461 aaggagatga gactgtaagg gtcaattttt ttccgatata atttgctggt aaatctatca
    44521 cagccaatga gagtccggga ttgctttctt cctgataatc tttccgttgg tataaaatct
    44581 tttcgcctag atatacagta atccattgat ggtttccttt gattagtaaa tttgcttcgt
    44641 ccaacggttt ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc acggtaggaa
    44701 tcgtacgagt gtacttgctg tcaaacttaa aatcaggatc atcttttgta tagaaaaccc
    44761 acgaatcttt tatttctttc atttgattgc tgtccgcagg agaaaaaata aaataaaaga
    44821 aataagcaat tcctgttaaa aataacaatg ataatataat gattatgctc cactttatac
    44881 gtaaataaaa agattctttt ttattatata tgttattaaa aaaagacata aaggtattcc
    44941 tttctaaaac ttgtaatgtt agggtaaacg ttttttaaac taacgtcaat tatttataat
    45001 aaaaaatgag ataaagatga ggaaatagaa ttagaaacat ataattatta aagggaaaca
    45061 tttttacagc tataatttga aaaaaattta tcgttattat atgattaaga aggattgaat
    45121 aaagaaagaa gttgaaaacg atacctgatt acaaaaaaat aacttttata agttctataa
    45181 cgttgattat atttttaatt cttattcttc tcgtcgtctt ggttccccga atttttggtt
    45241 tgactcctta tattattgag gacaaagaaa tgagtccata ttatgcacaa ggaaatctga
    45301 tatatgtacg accgaaaaat acaaatgaga ttttagtcgg agatattatt acatattatg
    45361 aaaattcagg aaaaaaaatc tcgacgcgtc gcgtaatagc cgttgaaaac aaccacgaag
    45421 atttttatac aaaagctgat acaaagactt atattgagcc tggagtagta aaaaagagaa
    45481 atattatcgg tagtcccatc tttcagattc catatattgg actagtcctt tcaaaaacgg
    45541 catttgcatg gattcagggg ttattcttta cgattgcttt ttgcctaaca ggaatcacag
    45601 catggaatac ctttgtagag ttgaaaaaga agcggagacg aacacagaaa tttttgtaag
    45661 aatgttaaaa acataaatgt attccagaga tccaacgact cttctgaaca tgaaacacga
    45721 gaaaacactc atgcagcttg tagatttagt cagttgttcg tataatgtgt gaagaggagg
    45781 agtagtatgc gcaatgaaat gatgcatcgt cctgtagtca aagaagaact attggatttt
    45841 atgcgtaccc agcaaaaaaa attaccgggt gagctaggca aactggaaga agaagctcat
    45901 gtagcagaag taccagttat tccccatgaa acagttgtat ttttgaaatt tttacttgga
    45961 cagcttcagc ctgaacgaat cttggagatc ggagcagcta tcggtttttc atcaagtgtc
    46021 atggccacga caatcggaga aaacgctcat gttacgacaa ttgatcgttt cgatgtcatg
    46081 atcgagaaag ctaaaaaaaa ctatgaacgt ctaggactga cagataaagt gactttgctt
    46141 gaaggtcaag cagcagatat cttgccggag ttgtctggtc cgtatgactt tatttttatg
    46201 gatagtgcaa aatcaaaata tattgaattt ttacctgaat gcttacgttt gttaagaaaa
    46261 ggtggcgttt tgatggtaga tgacatcttc caaggaggaa cgatcttgct cccagatgaa
    46321 gagattcccc gtggcaaacg agctatccat cgtaaattaa atgaatttct tcgtgttgtg
    46381 atggatcatc ccgatttgac atcgacaatc ttgccattag gtgatggtgt gatcttaatg
    46441 acaaaggaat cagaaacaat cgagttgtga tacatgatta tggcagcctg tagataatcg
    46501 attgaatcga gggctcaatt cgaacttgat gtaaaagttt ctatatttgt aagtcaatta
    46561 aaggatacag gaaatctaaa taaacaggag tagcatgaag tcaatgtagc tcctgttttc
    46621 aattgataac cttagaacag ctgaaggaga atgtctcgtt ttaaaagatt gatttagtag
    46681 ttgggccaaa ataattcatt atttgctaat taaataacta tttcgtattg acagaagcaa
    46741 tttaattatc tataattatt gatgttccgc tgattcttgt catagtagct cagctggata
    46801 gagcatccgc cttctaagcg gacggtcggg ggttcgaatc cctcctgtga cgctaaaaaa
    46861 ccgttagaaa ctgaggtttc taacggtttt tctttgtttt ttgtgccaat attgtttgtt
    46921 ttcaaaggca aataaaataa aaaaacatcc ttatcgagta caattataag gagcaaaaaa
    46981 ataaaactca tcagaaaaga ggaagaagat atgacgatac tatctagaat tttagtgact
    47041 ctagttgcaa ttgaattttt ttatatcatg tatatcgaaa cggtgagaac tgattctgac
    47101 acgacaagta gggtttttaa aatgagtaaa gaagagttaa gcagaaaatc tgttcaaaca
    47161 ttgtttaaga accaaggagt gtacaatgga ctattaggag tgggactact ttatggagct
    47221 tatctttctt ccgcatctaa agaaatcaca agtatgctat taatatctat tttttttgtt
    47281 gcattatatg gcagtttgac tagcgatcgt tggattttac tcaaacaagg tgggctagct
    47341 ctgttggcat tgctttctat tttcttataa atatagaaaa aataagaatt tatctaacag
    47401 gaaactttgt gaaaaatatt actttatctc atgaaatatg atattctaat gaatggtatt
    47461 ttagaaaatt tcatgaaaaa ggagttagat aggtgttcaa aaattatgtt tcctcactaa
    47521 aaaaagaatt ttcaggttat gatctttcaa gatttcagaa agatcttttg gctgggatca
    47581 cagtagctgc tgtagcattg cctttagcct tggcttttgg ggtatcaagc ggagctgatg
    47641 cggccgcagg tttgattacg gctatcattg ccggtatcgt tattggcggt ttatcaggcg
    47701 gtttttatca aatatcaggt ccgacaggtg cgatggcagc tatcttgatg tctattgcgg
    47761 caacaaaggg aatgcaaggt gtattgcttg ctactttttt agcgggtcta tttttacttg
    47821 cagcaggact tttccgatta ggaacactga cttcttttat cccagcaccc gtaattacgg
    47881 ggtttacttc aggtattgct atcattattg cattaggtca gatcgataat ttatttggtg
    47941 ttcactcgga aggtacaaac gttattgaaa aactaagtag ttatcaaacg ataggatttc
    48001 cgataaacac agcctctttg atcatgggag ggctagtcat tttagggatg tttatctatc
    48061 caaaaaaatg ggcgaaacga atgcctagtt cgctgctggc tatcattttg gcaacagcag
    48121 ttatgctatt gttccattta ccagtagcaa ctgtgggtaa gattccacaa acattgatca
    48181 gtagtaatcg tttgaatatg ggagatttta gcttttctgc cttgcaacaa gtggcagttc
    48241 cagctattag cattgcttta ttaggaatga ttgaaagctt gctatgtggt gcttcggctg
    48301 gccgaatggc aaataagccc ttagatagca atcaagaatt aatggcgcaa ggaattggaa
    48361 atctgttgct tcctttcttt ggcgggattc ctgctactgc ggccatcgcc cgtacaagcg
    48421 tggccatcaa atctggtgca caaactagat tagctggtat gatacatgca gttgtcttac
    48481 tgctctccat gcttgttttt gcgccagtga tgtcacagat tccaatgcca gcacttgcag
    48541 gtgttttgat tgtgacggct tggcgtatga atgaatggga aacgatcaag gagctattta
    48601 ctaataaata ttggtcagca gttctattgt ttatccttac gatgatttgt acagttatct
    48661 ttgatttaag tattgctatc gtgatcgggg tgatcggcgg ctgtgtattt tttgttgtca
    48721 aaagcgctgc tatcacgatt tcattagaaa cgatcgattg gcaaagaatg gggctgccag
    48781 aaacggaaaa gctgaataac tggacagtag tgtatattag tggtccactg ttttttatgt
    48841 cttcagaaaa actcaaaaat aaattggaag aactaaatca tcacgatggt gtcattttct
    48901 ccatgcgagg cgtaccaagt attgatttga cggcacgtgc agtttttgat gaatttcaag
    48961 aaaaagcaga gcaaagagga caaacgatta tctatacttc cttgcagcca gaagtagaaa
    49021 aacaactttc tcacttgtgg gaacatacat tcacgcatca acatcaaaca gttgctcatg
    49081 cgttgacagc tttacatgcg aaatatactg caattagcca ttaaaacaat gaaaaagaac
    49141 agacaagact gtaaactgaa g
//
LOCUS       DACDLM010000015        48169 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.015, whole genome shotgun sequence.
ACCESSION   DACDLM010000015 DACDLM010000000
VERSION     DACDLM010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 48169)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48169)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48169
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.015"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(23..388)
                     /locus_tag="IV356_000882"
     CDS             complement(23..388)
                     /locus_tag="IV356_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014590.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYAVCIIKRDK"
     gene            complement(563..2698)
                     /locus_tag="IV356_000883"
     CDS             complement(563..2698)
                     /locus_tag="IV356_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP9014591.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(2781..4436)
                     /locus_tag="IV356_000884"
     CDS             complement(2781..4436)
                     /locus_tag="IV356_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAP9014592.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(4438..4752)
                     /locus_tag="IV356_000885"
     CDS             complement(4438..4752)
                     /locus_tag="IV356_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAP9014593.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            4922..5182
                     /locus_tag="IV356_000886"
     CDS             4922..5182
                     /locus_tag="IV356_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HAP9014594.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            5196..5510
                     /locus_tag="IV356_000887"
     CDS             5196..5510
                     /locus_tag="IV356_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur reduction protein DsrE"
                     /protein_id="HAP9014595.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(5995..6549)
                     /locus_tag="IV356_000888"
     CDS             complement(5995..6549)
                     /locus_tag="IV356_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HAP9014596.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(6675..8603)
                     /locus_tag="IV356_000889"
     CDS             complement(6675..8603)
                     /locus_tag="IV356_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HAP9014597.1"
                     /translation="MDNEMISQLQFDRIKKEIQARAIGNYSKKRISDMTVSTNLQTVL
                     DRQEETREARLILESSQHVPFMGLPRIDALTEQVKKGLILQPTDLIEYADFLRSSRMI
                     TKFFDKNQYQTPLLFAYSKHLPDLINVEELIDQKIKNNKVSDDASRNLRKVRKQLQLI
                     EKEIQSKLLKFLRHPKNKEMIQEAMIVQKGEYYTIPIKASYKNKIDGTIIDESNKRTT
                     VFIEPTVISKLNEHYQLLKAEEISEEYQVLAALTGAIAENEEVIDLLIETITVLDIIF
                     ARAKFSREINGSTPRINKSEHIIIKQGRHPFLPEHAVPLDVEIGKDYRGLIITGANAG
                     GKTVVLKTVGLLTLMAMFGMQVPAKEGTELAVFDEIFVDVGDHQNLENALSTFSGHMQ
                     NIAAILKKIKRNTLVLLDEIGSGTEPNEGAALAIAIMESMYEQGALIIATTHYGEIKK
                     FAGDHEDFVPAAMAFDREALRPKYQLRVGETGESQALWIAHKMDMSMKLIHQAERYLA
                     EKAYRTQKKEFLPKTAVTNRKENKKERQLFAKGDRIFVNEYQKEALVYEDIGEDTIDV
                     YLDKKIIHVPRQRVRLVRSAEDLYPTGYDLDSLFIDYKTRKRQRDLERGSKKAHKVLV
                     KEMRKRQEERRVNDENSK"
     gene            complement(8909..9625)
                     /locus_tag="IV356_000890"
     CDS             complement(8909..9625)
                     /locus_tag="IV356_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAP9014598.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(9626..11449)
                     /gene="glpO"
                     /locus_tag="IV356_000891"
     CDS             complement(9626..11449)
                     /gene="glpO"
                     /locus_tag="IV356_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HAP9014599.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(11463..12959)
                     /gene="glpK"
                     /locus_tag="IV356_000892"
     CDS             complement(11463..12959)
                     /gene="glpK"
                     /locus_tag="IV356_000892"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HAP9014600.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(13095..14555)
                     /locus_tag="IV356_000893"
     CDS             complement(13095..14555)
                     /locus_tag="IV356_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP9014601.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(14545..15840)
                     /locus_tag="IV356_000894"
     CDS             complement(14545..15840)
                     /locus_tag="IV356_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAP9014602.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVKEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(16172..16849)
                     /locus_tag="IV356_000895"
     CDS             complement(16172..16849)
                     /locus_tag="IV356_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HAP9014603.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(16879..17970)
                     /locus_tag="IV356_000896"
     CDS             complement(16879..17970)
                     /locus_tag="IV356_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HAP9014604.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(18071..18505)
                     /locus_tag="IV356_000897"
     CDS             complement(18071..18505)
                     /locus_tag="IV356_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP9014605.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(19089..20546)
                     /locus_tag="IV356_000898"
     CDS             complement(19089..20546)
                     /locus_tag="IV356_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP9014606.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENL
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIEDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(20543..22438)
                     /locus_tag="IV356_000899"
     CDS             complement(20543..22438)
                     /locus_tag="IV356_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP9014607.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPITLLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSPVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(22496..24271)
                     /locus_tag="IV356_000900"
     CDS             complement(22496..24271)
                     /locus_tag="IV356_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP9014608.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARLPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYLVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESSEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(24321..25817)
                     /locus_tag="IV356_000901"
     CDS             complement(24321..25817)
                     /locus_tag="IV356_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP9014609.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     EIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRIWKEEDCAPVMLDGDEQYLQANTVDYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(26011..27633)
                     /locus_tag="IV356_000902"
     CDS             complement(26011..27633)
                     /locus_tag="IV356_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAP9014610.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESINAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTVPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(28083..29396)
                     /locus_tag="IV356_000903"
     CDS             complement(28083..29396)
                     /locus_tag="IV356_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAP9014611.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCILMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLLGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFMGFMWILNVK"
     gene            complement(29641..29865)
                     /locus_tag="IV356_000904"
     CDS             complement(29641..29865)
                     /locus_tag="IV356_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014612.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(29885..30253)
                     /locus_tag="IV356_000905"
     CDS             complement(29885..30253)
                     /locus_tag="IV356_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAP9014613.1"
                     /translation="MIQKTRVMLYVNDVEMICRFFVEKIGAEISETIELPEEFKSIVL
                     SISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETIYENMEEPGEITDNNGVLT
                     FNFSDPEGNYFVIGKAESSD"
     gene            complement(30449..31159)
                     /locus_tag="IV356_000906"
     CDS             complement(30449..31159)
                     /locus_tag="IV356_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014614.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGDESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(31177..31673)
                     /locus_tag="IV356_000907"
                     /pseudo
     CDS             complement(31177..31673)
                     /locus_tag="IV356_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(31710..32162)
                     /locus_tag="IV356_000908"
     CDS             complement(31710..32162)
                     /locus_tag="IV356_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003331879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP9014615.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(32297..32902)
                     /locus_tag="IV356_000909"
     CDS             complement(32297..32902)
                     /locus_tag="IV356_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAP9014616.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(33352..33972)
                     /locus_tag="IV356_000910"
     CDS             complement(33352..33972)
                     /locus_tag="IV356_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP9014617.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(33974..34843)
                     /locus_tag="IV356_000911"
     CDS             complement(33974..34843)
                     /locus_tag="IV356_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HAP9014618.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANKAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(34866..35273)
                     /locus_tag="IV356_000912"
     CDS             complement(34866..35273)
                     /locus_tag="IV356_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAP9014619.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDRHKLAELYEQVGLKFSELHENDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(35292..36581)
                     /locus_tag="IV356_000913"
     CDS             complement(35292..36581)
                     /locus_tag="IV356_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP9014620.1"
                     /translation="MSVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINDQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     ILLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFINATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(36608..36910)
                     /locus_tag="IV356_000914"
     CDS             complement(36608..36910)
                     /locus_tag="IV356_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP9014621.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(36935..39028)
                     /locus_tag="IV356_000915"
     CDS             complement(36935..39028)
                     /locus_tag="IV356_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAP9014622.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLEEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(39517..40245)
                     /locus_tag="IV356_000916"
     CDS             complement(39517..40245)
                     /locus_tag="IV356_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HAP9014623.1"
                     /translation="MGLCLFALPTQGFAVAGGHGGGTSSGRSSGRGSFGGRSYGGSYF
                     GSRSYGRDSYGYYGPSTGPSSYEQTGFLALAVLSVGGVSAFSIVKNKRQKKRLKSEIL
                     SRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFAEHQKVLQKNKAD
                     GVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLISGSKTQRQYFSQ
                     IWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(40391..43012)
                     /locus_tag="IV356_000917"
                     /pseudo
     CDS             complement(40391..43012)
                     /locus_tag="IV356_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298916.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
     gene            complement(43126..44457)
                     /locus_tag="IV356_000918"
     CDS             complement(43126..44457)
                     /locus_tag="IV356_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP9014624.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRVMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKANFGQLNELVPFGFAGMIASFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKNAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQSGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFVGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(44423..45901)
                     /locus_tag="IV356_000919"
     CDS             complement(44423..45901)
                     /locus_tag="IV356_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP9014625.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLKNPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(46206..48041)
                     /gene="tdc"
                     /locus_tag="IV356_000920"
     CDS             complement(46206..48041)
                     /gene="tdc"
                     /locus_tag="IV356_000920"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAP9014626.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEQVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     EQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKEIAKAMEKKLNEIIQ"
BASE COUNT        13759 a        10360 c         8045 g        16005 t
ORIGIN      
        1 gagtgtaaca taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgtattcaa
       61 aagatttatt tacttttttg tatagatttc gattgttcca cctagtcaat acaaatgagg
      121 taatcaggaa actgaaaaaa atcaatacaa aaaagccgat taagaaatac agcattttct
      181 tttctgataa aaaagcgtac aaggaaaaat ccttggctct ttctggtctc gttaatggga
      241 aaaagaccca tataaaagga agaacaacga tcatccatcc taaaagagcc actaacgttt
      301 gccaaatctt taaccagtaa ttaccttttg aaaaatactt atctttcacc aaaattgatg
      361 caacttcttc tcttgttact tttttcatat cctcacctca cgtttttttg ttacgacgta
      421 ggagtttacc atacatttca tttcttttca cataaagtgt tcctaaattt ttcctaagaa
      481 aaagaacaaa acatttctca tcagcaaatg aaaaatattt tgttcttttt atcagttgtt
      541 ctttttattt tttatctctt aattatgttg ctctttccaa tacgacaatg cttttcattc
      601 ctctagatat cgccgtgtac atttgtctgc gtcttctttg ctcatctcca tcgttttcaa
      661 atggatataa gattacatga tcaaattcca gtccttttgc tagactcaaa ggaatgattt
      721 ggcagttttc taatccatat gaattttttt taatcgattc ttgtagcgtt tgggtttcct
      781 cttctgtttg ggtgataact gccgcttttt ctccttttag agaaaccaaa atctcagcta
      841 gtattttcaa caattcttca gaggatcgaa aagagcggta ttcgggttct tttccttgcg
      901 gtcggatcga tacgatgtcg atcttctctt gatccacagc ataggttttg aaaagctctg
      961 tgattgctcc gctagaacgg taactatttc taagatcata ccgatggatc ggcagatggt
     1021 agtcatcgaa acaacgcata atatcagcaa aagtagtgga agaattaaag attgcctgat
     1081 tctcgtcacc tactaaagta aagtgagttt ttggaaataa ttcgatcaat agacctaatt
     1141 gtgccagggt ataatcttgt acttcatcaa tcaatagata gcgaaatgct ggtacattta
     1201 ccttttcaac aagtaaatga cgaatagcta atataatgac tgcttcatca acagtacgtg
     1261 tgggttgcca agcataagct gagccatatc gtttttcata aattctttca aacaactgat
     1321 gctcatccac ccatgccatt tcttcgattt gtctggttat ttttcgatat tttttttgta
     1381 aaagtttcct tgcataagct acaatacttt gttccgaatc atcagaaatc aatttaccga
     1441 ataattccaa ctgcctatct tctgtcaacg agagtacctg attctgcaca gcaggacttt
     1501 ttgcttgttt caaaagatga ttcttccatt cgctcatcag tgcctttttc gttgcttgaa
     1561 gcctatcgat caatttagga tgagcaggaa ctttctcata tattttttcg atcgtttttt
     1621 tagaaaggac tgtttttcca tttttagtaa gtccacggat aaaattcgga tgatctaaaa
     1681 acaaaggatc tgattgtttt agattatcga taaacttttt gctacgcaaa cgttctgtct
     1741 gctccgatac attttctccc gtgatacgtt tgaaataagc ctcttcacct tctatttcct
     1801 ctgctgaaag ctgtgaaacc agctgtatga tggttagatt cagtggattt ctttcaccta
     1861 atgatggtag gacattcgaa atatagtcga taaaccgatg attaggtgat agaatcagca
     1921 agtcatcgga tgtcatcgta tctcgatata aatagagcag atacgcaata cgctgcatga
     1981 tagcagaggt tttaccactt cctgctacgc catttaccaa gatattttga cttttcacat
     2041 cccgaatgat tgtgttttgt tccgattgga tcgtagcagt gatagccttc atttcattgg
     2101 tctcatcttg gcctaagact tctaataata cgtcatcttg aatagctaca gacgtatcaa
     2161 aaaacttgac caaacgatct ctttccaaaa gaaattgtcg tctttcttta ataaccgtat
     2221 cgattttatt ttgacgaacc gtataagaag atggaccaat catgttattg taaaaaagtt
     2281 cggcaattgg tgaacgccaa tcataaacaa gattttcatc tgcatcatct gtgaaatttg
     2341 ctgtaccgat ataaaaggat tcttttggct cattatccag aaagtctaca acgacttttc
     2401 caaagtaggg acttttcaat aaacgttcga tctttgctag ctgattttct gcgtttttct
     2461 gtttgatatt catctgatcg atttctctat ttttcatttc aatcatcgaa aaagtatcca
     2521 ggttatctaa gtaactgtca aaattcaatc gaagctcgcc agccatttct ttcaacgact
     2581 ggtttccttc tatttttgcc gtatccatcg attcccgcag ttcgtttttt ttatcaatta
     2641 gcttttgata cacgttcttc agatatgctt cttctaactg tttttgtgtg ttgaccatac
     2701 acattctcct ctttttttaa agtggtggaa ccgattagtt tacctctttt aagagtcgaa
     2761 tgcaagcttt ttaacgagta tcatttgtta ggatatatca gttcttcagg tcggacagtt
     2821 tgatataaag aaaatgcacc atcaaggttt tttacgtggt agccagactg cttcaagatt
     2881 ctttccgcta gatagctacg taatccgcta tgacagctga cgatatattc ttgttggctg
     2941 tctaattcat ttaatcggtc ccgaagttca ttcaaaggga tatgtttggc ttccttgaat
     3001 ttgccctttt ccaattcttc tgctgttcgc acatctaata aaatttttcc ttttgctagt
     3061 tctgtcggca attcatgcca ttgtacggtt tcactaagcc cttctgcaat gttcattgct
     3121 gcatatccta gcatgtttac tggatctttg gctgagccaa atggcggtgc atacgtcaat
     3181 tctaattccg gtaaatcgaa gatcgtcaaa tgccctttga ttgctgttgc taaaatatcg
     3241 atccgtttat ccacaccttt tgccccaaca ccttgtgcac cataaatctc gccagtctct
     3301 ggatggaaga tcaacttcag taaaatatct gttgcttctg gataatagct tgcatgatct
     3361 tttcctgata catgaatgac ttcaaaagac agttcgtttt ctttggctgt tctttcactt
     3421 aaaccggtgg atgcggcagt cattccaaac gttcgtataa ttgctgttcc aataccgcct
     3481 tgatttcttc gagaaattcc ggaaatcgtg tccgcaactt gtctaccttg acgattggct
     3541 ggtgaagcaa gagaaataag tgcatctttt ccagtgattt gctgttttac aacgatagca
     3601 tcccccaccg cataaatatc aggaatattc gtttgataac gttcgtctac taggataccc
     3661 ccgcgtatgc ctaattcgat tccagcggtc actgctagct ggttatcagg acgaacacca
     3721 atggataaaa taactaaatc agcagggatg gtacgcccat catccagtcg caatcgtttc
     3781 ccgtggtctt caaatccagc gacagcatga gaagtaatca cttctactcc ttgatgagac
     3841 aattcttttt ctataaaagc tgccatttct tcatccagtg ttggaagaat atgtggtgct
     3901 tgttcgatca ccatgacttc taaacctctt ctttttaggt tttctgccat ttccaatccg
     3961 atgaatcctg caccaacgat cacggcacgc tttggctgtt tttctaatgc atgcatcact
     4021 ttatcgatat ctggtacatt tctaatagaa aaaacattgt cggcttctgt tatccctgga
     4081 atcgatggaa caactggttt tgcaccagga gataaaacca atgcatcgta ctgttcaatg
     4141 tgtttttgac cctcatgtac gacttctacc gttttgtttt cgggaaagat ggctgtcact
     4201 tcatgatttg gacgcacatc taaacaaaaa cgagcggata atgattctgg cgtttggaca
     4261 agaagatttt cccgttcact gatttctccc gaaagataat aaggcaagcc gcaatttgca
     4321 aaagaaacat acggtccttt ttcaaaaaca acgatttctg catcttccat taatcggcga
     4381 agccgtgtag cagcagacat tccacctgct acacctccga caataacgat tttcatctta
     4441 tttccctcct actgttcgat caaaccattg attcatgcca ccacgtacat tcactacatc
     4501 ataaccagat ttctttaatt ctttagctgc ttgtttactc ctcatccctg attgacaaat
     4561 cacatagacg gtcttttctt tgtctccatc atatctgttt atactttgta atggaacatt
     4621 tttagctcct tttatatgcc cgccccggta ttctgcaggt gttctaacat caagtaacgc
     4681 tggattttcc aaaagctttt cctttaattc tgggactgtt atcgatttta ttgattgaaa
     4741 tagcaaattc attttctgca cctcatttac atttttataa atacctcatg gggtatatta
     4801 aacaggagct ttattaatat gtcaaccaga atgactcttc atttttttca ctacttttta
     4861 tatttgcata aaataccgat aaggggtatt atctaattat aaaaatagag gagaatgtgt
     4921 tatggagatt gataataaaa atatcctgaa ccgtttgaaa cgtacagagg gacaaattcg
     4981 tggtatccaa aaaatgatcg aagacgaaaa agaatgtatg gatgtcatca ctcaattaag
     5041 cgctgttcgt tctagtattg atcgcgtaat gggcatgatc gttgcagata atctgaaaaa
     5101 ttgctttgag aaacctgata gtaatccaga agaacaagcg gctaaactag aacaagcgat
     5161 caagatgatt attaaaaagt aaaggaatga tttcaatgaa agtcgttttc catattgatg
     5221 aattagaaaa atggtcagaa acagggaaaa acgtaaaaaa cctgataaaa gcttctccag
     5281 aaacgacgat tgtcgtatct gtaaatggca tcgcgattac cggttatcta gactctgcca
     5341 atgcagaatt cttagatttg caaggagtcg tttttcacgc ttgcgccaat gctatgcgtg
     5401 ctaatcatat ttcagaaagt tctttacctg aacaagtaat cgttgtacca gcaggtgtcc
     5461 ttgatttagt tgaactgcaa tcccaaggtt atgcttatat caagccttag tcagtagagg
     5521 ttgcgacaga agtgatcagc ttcaagaaat ttcggcttat ttttcgaaga agctacttct
     5581 ggaaaaccgt gaatcaaagg ttgtgaaaac gctgtcctgc atcaagtaat aagaacagcc
     5641 aaacaaaaat agcttctcat atttttcgtt tggttgggct tattaccgca gatgcaagct
     5701 tttgaacacc gtttaaggaa gaggttgtga aatcagcggt ttgacctaag tattagagaa
     5761 aaaaacggga aaatagctcc tcatattttg ccgttttttg agctaatacc gaaggtcagc
     5821 tgattgaaca ccgtttacca agaggttgtg agcctaccat ttaactccga atcacaagaa
     5881 ataatttcaa aaacaacttc tcctgttttt ggtttggttg gcttattatc gagaagtagc
     5941 tactgggagt ctatttatca aaaaaaggaa tgcgacatag gtcacacccc ttttttattt
     6001 tctttgaaac atctttcggt actcgacagc atacaagaca aaagattgta aaagaccgta
     6061 agtgatgacg gcaaaaatga ctctcaccca cagcgttggt aattctggga aaagcagcaa
     6121 aaggatcatg ccaacataga tgacagcagt cgctactttg ccataccact tcgctccact
     6181 taatttgata tttttagata gcccgattaa tccagctaca aacataaagc cttcttttat
     6241 caagaataga ccaaacaaca gccaaagcca cggtcgatac catgccatag acaaaatcag
     6301 aaaaagttgt gtcaatttat ctgcaaacgg atcaagcacc ttccctaagt ctgttacctg
     6361 attatatctc cgagcaatga ccccgtctag ataatcagac aaacctgaga caacaatgac
     6421 cgctcctgct atataaaatg actgtctcag cacaaaataa agataaatcg gcagcaaaaa
     6481 aatacggaat atcgataaaa gattcggaat cgtttgtatt tctttacgcc agtctgtgct
     6541 taatttcatt ttatcgccct acctcctcag cactcttttc tttttatttt agcttacacg
     6601 gggaataaaa ccaatgattt cactgttttt atttttcttt acagccactg atattatgag
     6661 ctaatttgag ataatcactt gctgttttca tcgtttactc ttctttcttc ctgtcgtttg
     6721 cgcatttctt ttactagtac tttatgagct ttttttgatc ctcgctctag gtcacgctgc
     6781 cgtttacgtg ttttataatc gataaacaga ctgtctaaat cgtaacctgt cgggtacaga
     6841 tcttctgctg aacgcaccag acgaacacgc tgacgaggca cgtggattat ttttttgtct
     6901 aaatatacat caatcgtatc ttcacctata tcttcataaa ctaacgcttc tttttggtat
     6961 tcattgacaa atatccgatc accttttgca aagagctggc gttctttttt attctccttc
     7021 ctatttgtaa ctgctgtctt aggaagaaat tcttttttct gtgtccgata ggctttttcc
     7081 gccaagtaac gctctgcttg atggatcaat ttcatcgaca tatccatttt atgagcaatc
     7141 cacaaagctt ggctttctcc tgtttctcca acccgcaact gatatttagg acgaagtgct
     7201 tcccgatcga aagccatagc agccggcaca aaatcttcat gatctccggc gaatttcttg
     7261 atttctccat aatgggtcgt ggcaatgatc aatgcccctt gctcatacat agattccatg
     7321 attgcgatcg ctagtgcagc cccttcattt ggctctgttc cactgccaat ctcatctaaa
     7381 agtaccaacg tattcctttt tatctttttc aaaatagcag cgatgttttg catatgacca
     7441 gaaaatgtac tcaacgcatt ttctaaattt tggtggtcac cgacatcgac gaaaatctca
     7501 tcaaagacag caagctctgt cccttctttt gccggaactt gcataccgaa catcgccatc
     7561 aaagtcaata aaccgactgt cttcaacacg actgttttgc ctccggcatt tgctccggtg
     7621 ataatcaagc ctcgatagtc tttaccgatt tcaacatcca atggtaccgc atgctcaggt
     7681 aaaaatggat gtctgccttg cttgataatg atatgttccg atttattgat tctaggtgtg
     7741 cttccattga tttctcggct aaattttgcc cgagcaaaga tgatatctaa caccgtgatc
     7801 gtttcgatca ataaatcgat cacttcttcg ttttctgcga tagcaccagt caatgccgcc
     7861 aggacttgat attcttcact gatttcttca gcttttaaca actgatagtg ttcattcaat
     7921 ttagaaatca cagttggttc aataaaaacc gtcgttcttt tatttgattc atcgataatc
     7981 gttccatcta ttttattttt atagctggct ttgataggaa tcgtatagta ttcgcctttt
     8041 tgaacaatca ttgcttcttg gatcatttct ttgtttttcg gatgacgcaa gaatttcagt
     8101 aattttgact ggatttcttt ttcgattagt tgtaattgtt tgcgtacttt acgcaaatta
     8161 cgtgacgcgt cgtcactgac tttattattt tttattttct ggtcaatcaa ctcttctaca
     8221 tttatcaaat caggaagatg tttgctataa gcaaacaaca agggtgtctg gtattgattc
     8281 ttatcaaaaa actttgtgat catccgactg cttctaagaa aatccgcata ttcgatcaaa
     8341 tcggttggct gcagaatcaa cccttttttg acttgttctg tcagtgcatc gatcctcggc
     8401 aaccccataa atggaacatg ctgactgctt tctaagatca agcgtgcttc tcttgtttct
     8461 tcttgacgat ccaagacagt ttgtaggttt gtcgagaccg tcatatcgct gattcgtttt
     8521 ttgctatagt ttccaattgc tcttgcttgg atttcctttt tgatccgatc aaattgtaat
     8581 tgactaatca tttcgttgtc catattctct ccttttcttg aagagatacc tgtcccaaaa
     8641 taaataaggg cctagagata aataaaagga tagaacacag cttaaaaaag tcatgtccta
     8701 tccttattag aatacaaaga tattgttttc ctgacaggta ccgtttcata agcacaccaa
     8761 ataaactttg tttattggct attcgactta ctgattagat accagctaca ctcacaaaac
     8821 ataccccatt cttctaggtc ttatttattt tccacttaac tatagcaaga cacattttgg
     8881 ttgtcaaact ttagtatgtt ttatagattt acaccattaa tgaatagaca cctaccgcga
     8941 taattgctcc gatcattgga cctgcgattg gtacccatga atatgcccaa tctgaagttc
     9001 ctttattagc tattggcaat accgcatgtg ctaatcgagg accaaagtcc cgagcagggt
     9061 tgattgcata tcctgttggc cctcctaatg aaagaccgat ggctaagatc aatccaccta
     9121 cagcgaatac gttcgttcca ggtgcaaatt cgttttgtcc aaaagctagc aacccaagaa
     9181 ctaatacaaa tgtaccaatt aattctgtga tcacatttgc tggataattc cgtatagcag
     9241 gacctgttgc aaacgttcct aaaatcgcgc tttcatcttt cgttgcattc caatgtggca
     9301 aataagaaag ccaaacaaga atggcccctg caaaagctcc taaaacttgc gcaatgatga
     9361 aaggaacgac aagattccaa ctaattgccc ctgtcatcgc catagctaga gagactgcag
     9421 gattcaaatg agctgggccc atgaatccag aaatatagac agccattgtt acagcgagtc
     9481 cccaaccaaa tgcgatgaca atccagccag aagcctgtgc tttacttttg tttaaattca
     9541 cagccgcaca cacaccatct ccaagcaaaa ctaggatcag tgtcccaata aactccccca
     9601 tgatttgagt catatcactg ttcatttatt tctccccctt tagttcccgc agatctgatt
     9661 ctgcaatcaa tgcttctaaa cgtttagtct gttgcgcctt ctcctcttct gtccattcaa
     9721 aatatccagc aattgcatcg atcacaggtt gcttgatctc atcaagctga tctcgttcaa
     9781 acaacagatg atttgtacga cgaatgagat aatcgcctgg ggccaaaacc atttcttctt
     9841 ctaaaccata acgtaaccga gctgactcag cgagactcaa accaggataa ggtgccattt
     9901 cttttgctaa ttcaaagata cgtcgggcat tagtcccgta aaaatcagcg atataagtag
     9961 catcttcttc ctctaaaccg gctgctactc cttcttttgc taattctgtc actgtttctt
    10021 ctaatttagt tggatcgaag tttccacctg aaatctgata ttttttagag tcgatttctt
    10081 tcgtctctat tccgtattct tcttttaata attggcgtat caatcgcaaa gctccttctg
    10141 ccatcttacg gtaatcggtg attttcccac cagataaagt cagcaaacca tctggttctc
    10201 tttctaaaga actacctctg gaaatcgtag aaggtgcttt ttcatcacgg ctgttttcca
    10261 aatggttcaa cacgtcttct acttcagcac gagaaacttt gttttcctta tattcactta
    10321 ctgtatcgac aactttattg aagctcttgt ctgaaatcga tccattatct ccaccattgt
    10381 aatcagaacc agaattacca atcaacagtg gacgaagtcc tgcccagctt gcttcgatat
    10441 cattcaatgt gatatttgct tctggatagc gatgattgat cacatccaat agataatcta
    10501 catcttcttg tgtgactttc ggatccgtaa aatctccttg gtaatccgta tctgtcgtac
    10561 caaagtaagt cttgttttct cttggaatag caaaaaccat ccgcccatct tgctttcctg
    10621 tatcgaagta tgtgggttgc ggtacaggca gttttttcgc atctacaact aaatggatcc
    10681 ctttagttgg acgcatttta ggagagactg gacgcgtaaa attcaagttt cgtactttat
    10741 ctacccaagg accactcgta ttgatcacta attttgcttt gatttcgatc acttcatctg
    10801 tcagcaggtc acgagctttg acgccaacga tttgatcgcc atcatataaa aagccaaccg
    10861 ctttcatttt acttactaga taagccccat cttcggcagc ctttttgata ttatcaatca
    10921 ctaaacgggc atcattgttg cggaaatcta gatagacacc cgcgcctttt agcccttctt
    10981 ttttcaaaaa cggttctctt tccaatactt cttctggtgt cagcgtataa ttctcatatt
    11041 tggttcctgt cacatttgcc agtttgtcat aaaggtccat tgctactttg accgagaaca
    11101 tattgaaggt tgttgctcct tcgccctcat agattggcaa aagcattgga tctggttttg
    11161 ggatgtgtgg ggcaatactt tgtacgactg cacgttcacc aactgtgtca gctactactt
    11221 ccacatcaaa tgtcttcaga taacgaatac cgccatgaac aagtttggtc gagcgagagg
    11281 aagtcccttc tgcaaaatcc tgcatttcga tcaatcctgt tttgattcct gatgctgctg
    11341 actggactgc cacaccggca ccagtgattc cgccaccgat gatcaacaga tccaattctt
    11401 cttgctgcat tttttgaatg ctatcttgtc ttgtcttgtt tgaaaacata tggatttcct
    11461 ccttattcaa atgcttgggt agcttttact gcttttttcc aaccgttgta aagtttttct
    11521 cggcgctctt cctccatttg aacttcaaat agcttgccag cttcataaaa ttcgcggatc
    11581 tcgtctgtat ctttccaata accgacagct aatcctgcta aaaatgctgc ccctagcgcc
    11641 gttgtttcca agttttctgc tcgttggatc ggtacattca agatatctgt ttggaattgc
    11701 atcagatatt cattgtttgc tgcaccgcca tctactttca atacaggaat cttgattcca
    11761 gtgtcatctt gcatcgtatc gatgatatct ctcacttgat aagcaatcga ctgtaaagta
    11821 gctttaatga tatcttcttt tgtcgtacca cgtgtcaagc caaacatagc ccctcgtgct
    11881 gcctgatccc aataaggagc acctagccca acgaatgcag gaacaacata aacctcatct
    11941 tcgcttgtag agcgtttcgc ggcgtcttct gaatcgctag ctttttgcaa catttgaagt
    12001 ccatctctca gccattgaat cgaagaacca gccacaaaaa tacttccttc taaagcatag
    12061 taaacctttc catttatgcc gtaaccaatt gtcgtcaata aattattttt ggataattgc
    12121 ggtttttcac cggtattcat gacaataaat gaacctgtac cataagtatt cttgaccatg
    12181 cctggttcga atgccatttg tccgaataat gcggcttgct ggtctcctgc catccctgaa
    12241 attggtgctt cgcttccata aaaatgataa ccttgcgtat aaccataaac ttctgagtta
    12301 gaagtgactt ttggtaacat cactcgagga atatttagta aatctaaaat ctcctgatcc
    12361 caatctagct gatggatatt gaacaacatc gtccgactgg cattcgagta atcagtaaca
    12421 tgtgcttgtc catcggtcag tttccatact aaccaagaat cgatcgttcc aaacatcaat
    12481 tcgccttttt cagctcgttc ttgcgcgcct tctacatgat caagaatcca gcgtatcttc
    12541 gttgctgaga aataggcatc gatcactaac cctgtttttt cgtggaaaaa ttcttgatag
    12601 ccttcatttt ttaagttatc tgcaattcca gctgactgtc tggattgcca aacaactgca
    12661 tgatagattg gacgtcctgt atctttttcc catattactg ttgtttcacg ctggttcgtt
    12721 atgccaatcc cagcaatctg atttggtttg atccctgatt cgatgaacgc tccggcaata
    12781 actgactgta cagaattcca gatttcattt gcatcatgtt ccacccaact ttcttgcggg
    12841 aaatattgcg tgaactcttt ttgagaactg ccgatgtgtc ttcctttctt gtcaaagata
    12901 attgctcgtg agctagttgt accttggtca atcgccatga tatacgttga ttctgtcatt
    12961 gtgattccct ccattatatg caaacgcttt ctttaactac tcttatcata ctactgtttt
    13021 aaaaaaagaa actgtcaaaa ttttattctt tttttctttt tttgacagtt ttttattatg
    13081 aagctatttt ttaatcaatt cttttctttt ttcagcgtct ctattcttct tttcaatcga
    13141 ataatgtcgt aaggtgacgc aaattctgac agataatatt cacactgttt tttgtttctc
    13201 tggcaaaatg tgatcaccaa atcatattct ttaccttctt cataacttcc aatctcaata
    13261 ccgccgattc ccctcagttc tctgatcaga tattgttgaa aagcaatacg ataaatcggc
    13321 agactttcta aatcgattcc aatcactact ggttttgcaa tataaaaatc gatcatcaaa
    13381 agaacattgg catactggat catcaggtaa ctaagctcac tatcttcagc tcttttcctc
    13441 ggcaattgct gcaccgctgt ttcctgtaat ttcgccagta actgtgttaa ggaatgcccg
    13501 agcattttct gctgctgttc caaaagccga tcacgctcat agacttcgat ctttccaaca
    13561 aagaaaaacc attcattgtt gatctgggaa atttggtagc ctactgcctt ttcttctttg
    13621 attttcaaac gacgaggacg ataatgccat aacatcgttt cccgaatgta agtatctaaa
    13681 acagcggttg gtaacttttt gctccgtgtc aaatcatact gataaaatat ttcttcgtct
    13741 actatcgaaa aagaaacaaa aaagctgtaa aacatcattg tttcgtatac attcagttct
    13801 gctgctgttc gactaagatg catcacgatg attggatcga ttgcttgata aagccggtcc
    13861 gactgataga gtaatttctt ttctttcaaa gttgcgtacg tacttttttc attcaatagt
    13921 ctttttttcg taatcccgag ccagcaagca atctgtgctt ctgctgatgc cgtaaacgtt
    13981 gtttctaata cacggtccaa tcctagaatg aacggtcttt tttctggtgt attttgcaaa
    14041 aaaagcggtc gctgatcttc cgggatatat tggaatagtt cataataaaa atatcgtatc
    14101 tgtagctctt ctccgtataa ttgaccgttt ttgatttgta atccaaattc ctctaagagc
    14161 tggttcaatt ctttgatctt tcgaaaaaca gaagactcac tgatattaaa cgctgtcgct
    14221 aatcgaacga tggatacttg ctgatgttct aataaataga cgagcatctt aaacttcaag
    14281 ctttcctgca ataaaaacaa tagaattttt tccaaactta catcttcgtc caacacaagc
    14341 agcgcctgat actcatttcg ctgtacttct actttttttt ccatcattcg gccaatcaat
    14401 tcaatatctt ccaaatattg atcaaacgag gcttttgaca gttggacatg ctctctcaaa
    14461 ccattgatag aggctgttcc cccttgcaga acaaggtttc gcaaaatcag gatctgtaac
    14521 tgctcttttc tttctaataa tgcttcaatc ttcataggca gtattcgcca cctttgacca
    14581 caccatatct ggcacacggt attctggctg gaaaaatagc tcatgttctt ctaactgttc
    14641 aaacgtccat ccttctttta ctgcaattgt cagttggtca agaaggtgga acatctcttt
    14701 tttgctttgg agctgtgctc caagaatctt tttttcagaa tcaaatagaa atttgagttt
    14761 aactttgctt tgatttattg ctgtaagctt gtagtctacg tatcctgttt caattttttg
    14821 gggataaaaa atgctctctt cttctgtcaa acctacgctt cctaagaaat agccaaacca
    14881 ctgattgccg actggacgat aggttccctg atcctttgtc tgtgagccac taattgtctt
    14941 gctgacattt cgtgctgtac ggacagcgtt atttactaga gaaacataca ttttttcatt
    15001 tgttggacga aaagttactt ggatcgcatc gccaatcgca taaacgtctt tttgagacgt
    15061 ttgcaagtag tcatctaccc agatcgttcc atcatcattc aatgttaatt gttcttccca
    15121 catctgattg tcggggcgag aatgattagc cagcaaaaca agatcatagt tctcctttct
    15181 tttttccgtc tctacaatag cggtttcatt ttcggtcaaa gacacaactt gttcttctaa
    15241 aaaaagtgaa agcccttgat ttttcatttc ctttactaac ggttctgtca tttcaggatc
    15301 tagataacga aaaagaattg actttcggct ttcgtaaaga tggatttgtt tttttcttga
    15361 tgccaaccct tcagctattt cgattcctgc ttgtcctgca ccaataattg caattttctt
    15421 tgcattcatg atcttttgct gaagagccgt tacgttttgt atctttttaa ctgggtgaat
    15481 aagcgttgat tctgcagaaa tatttcgaaa cttttgattt gaaccagtcg ctagaatcaa
    15541 acgatcaaaa tccaattttt ttcctcctgc taaaacgact tttttttctt tcaatcctat
    15601 tactgtcttt tctgtgtaaa catggattcg atagcggtca gtcagttctt ctttcgtgat
    15661 ccaagaaagt tgtttttcac tggtaacctt tccttttaat atcaaattga acccgctggg
    15721 aatccatcct aacttcgatt gcttttcaat caaatatatt tcacttgttg gcatcaattg
    15781 gcgaagataa atagccgcat gaatccctgc aaacgacccg ccgacaatta caatgttcat
    15841 ctgcattcct ctttcttata aggtgttcta ctgctaactt ctcaatcaga aaacacagta
    15901 ttcataactc gctttcaacc ttatgataca tagcgatgca gcagaatcaa ccctctccat
    15961 cataccgtgt tctaggtctg cttctcaata atgtactagt ggacctaatt gaagagtatc
    16021 atttctgaag agatgtttca aaaaatgtac tcttataaaa gaaaaaaact cgccttttac
    16081 gtacctctgt ccaaatagga aacagaaaag aacgaaaaga cgagttttag cgtgtgtaat
    16141 gtaatagtta gaatagacac atcatttatt tttaattctt taatgcttca acaactgctt
    16201 cgcctaattg atgagcagat tgaggatttt gccctgtaag aagccgccca tcaatttgaa
    16261 ccacttctga aaaagctgct ccagactgat agtttgctcc tttttctttc aaagcatctt
    16321 ctgctaagaa tggtacttca ttcgttgtac catttgcttc ctcttcttca ttactgaacc
    16381 cagtcactgt acgtccagct aaaatagatt ttccagactc atctgtaact ggcaacaatc
    16441 ctacaacacc gtgacaaaca gctgagacca gcccttcatt tcgatagatt tgtgaagcga
    16501 ctttcccaag atctattgct tctggaaaat cccacattgt tccgtggcca ccagcataat
    16561 aaaccgctgc ataatcattt gcatccacat catcaggacg taaggtattt cccaaggccc
    16621 gatttctgaa atcttcatct tcataatagg cccaatcgat ttcatccata ttcaaaacac
    16681 tttgcggttc taaaggtaca tatccgcctt taggactgac aaaatctgca tcgatcccat
    16741 tttttactaa tacatcataa aaatgagtca gttcacttaa ccacaaacct gtaggacgct
    16801 cgatcttttc gtacttttct acatttgtta atacgatcaa tactttcatt ttcccatcct
    16861 ctttctataa aaattgcgtt attgataacg tgctttcaag aaattatata atgggcttgg
    16921 caaataaagc tctttatatg cttcttcaaa aggtttcgtt acaaattcat cctcacggtt
    16981 ttccaataat ttctctgccc agtcaggatc gacgatcatt tgctgtccaa ttgctgcaag
    17041 ttctgcatat ttcaatacct gctctacatc ttcgcgattg cggatcccac cgacaccaac
    17101 taaagggatc tttccttgaa tcgtgttatg gaccacttca agaatcgatt tatcgttgta
    17161 tttatcagaa cgagctattc gatcatacat atttaatgaa acatgcagat aatctagttt
    17221 tgactcacgt aatcgttcaa gaagccagat cgtgtcttca aaacggatac ctggtgtttc
    17281 atattcttct ggtgagaaac gataccctac gatgaatggt tttttagcat attgttcaac
    17341 cgctgagaaa accgttgtta ataattcttc aataaaacga taacgatttt ccaagctacc
    17401 gccccattga tcctctcgtc tattcgaatg cggagagaaa aattgttgga tcaaatacgt
    17461 atttgctcca tgcaactcga ttccatcaaa tcctgattca atcgctctac gtgtggcttt
    17521 gccaaatgct tggattgttt caacgatttc ttcttcactc attgctcgtg gtgtttccgc
    17581 atcaggacgt tttgctgcaa ctgcacttgc agatacaggc tgttctccag ataaagttgc
    17641 tcgacttgtc attcgtccac cgtggaaaat ctgaataatc gcttttgcgc cttctccttg
    17701 gattgctttc gctagctcac ttaatcgagg aatcatttca tcatgagcga tgctgagttc
    17761 acctggccag ccttttccga tatcttggac atttgcagca ccagtaataa cagcaccaag
    17821 acctttagaa cgttgtttat aataagtgat ctcatcttcg gtgatcactc cattgaaaaa
    17881 gctgagttgt gtcgtcatag gcgacagcat caatcggttc ttcaattgaa ctcctgaagg
    17941 taaagtaatt gattgatcaa attgtgacat tgtcattcct cccataattc gctctgatta
    18001 acctatcgag aatcatctat cattaaacca ctcgattagt tgtacatgca actaatttgc
    18061 ttaaaaaatt ttattttttt tgtaacttat ctgttgcatc attcattgtc tgggctaatt
    18121 ctttacttgc ttcatttccc aaaactgctt tgtatgactg atgaagttct tcccagctac
    18181 catcgacttc cttagcaaat tggcgtcctt gttctgtaag ataaactaat gacaagcgac
    18241 cttcgctaac tgttttgacg tatcctttat attctaattt ttcaacaaaa cgagcaatcg
    18301 ttgatggggc ggaatagagc atttgtgcaa tatctttttg tggtattcca tctttttctt
    18361 ttaatatcaa taaaataaaa ccataagttg gtgccagacc tgtccttcta aacgcttcat
    18421 cagctaattt attcaacatg cgatctagct ttttcacgct aaagaaaaga cattcatcta
    18481 acgctttttc aattggcttt tccatttcat cccctccatt ggcgtacata tcatagtatg
    18541 atttttattt tttgtcaaaa aacacggaat aatgtccgcc tcctctgtct agatttgaaa
    18601 aaaagaagta gccatcttca aagaatttcg gcttgttttc gacaaaactc cttctggaac
    18661 accgtgaatc agaggttgtg aaaaagtcgt ttagttttga gtatgaagaa aaattttgtg
    18721 aaaatggctt tccacatttt tgcataaatt tggcttaata ccgaaaaact ggcttttgaa
    18781 caccgtttat atcagaggtt gtgaaaaagc cgtcctgcat caagtaataa gaacagccaa
    18841 accaaaatag ttcctcatat tttgtcgttt tttgagctaa tgccgatggt cagctgattg
    18901 tacaccgttt attgagaggt cgtgagcctg ccgttgaact ccgagtcaca aggagcaatt
    18961 tcaaaaaaca gcttctcatg ttttatgact atggtgactt gtgatcgagg agttggcagg
    19021 agaatactgt ttattcgtaa agaaggggct gtgacaagac ttttgtcaca gtcccttatt
    19081 tccttttatt ataggatttc gccatttgat tggatgactt gtctgtacca atcaaatgat
    19141 tttttcttta accgtttctt tgtgccattc ccttcgtcat cttgatcaac atagatatat
    19201 ccataacgtt ttgacatttg tgaagtagaa gcgctgacga tatcaatgca gccccacgac
    19261 gtataaccaa ataaatctac tccatcttcg atagcttcct tcatctgctc aatatgctgc
    19321 ttcaaatagt caatgcggta atcgtcttga acggttccat cttcttctac tttgtctata
    19381 gctccgagtc cgttttcagc tatgaacagt ggtttttgat acctatcata taattgattc
    19441 aaagcaattc tcaaaccctt aggatcaatc tgccagcccc attcacttga tggaagatac
    19501 ggatttttaa ttcctccagt tattaagttt ccttggaccc cttccaaatt ttctggatga
    19561 gcactgactg cactagacat gtagtagcta aaagaaacaa aatcaacagg gtaggctgct
    19621 aagatttctt catcacctac ttctattttt aagttgacac ctttttcttc aaacattcgt
    19681 tgcgtatacg ctggataata tcctcttgct tgaacatcac taaagaacaa agaagttctt
    19741 tgctgctcaa ttgttttttg aatatcatcc ggatcacaag aatacggaac aagaagctga
    19801 tagctgatca tacaaccgac ttgtgaacct ttgataattt catgacaagc ttttgtagct
    19861 aaagcacttg ctataaactg atggtgtgca ccttggtatt tcgcttgttc caaatgggga
    19921 tggttttctt caattactcc tacgctaaca aaagggtgat gttttacaca gttgatctca
    19981 ttgaaagtca tccaatattt tactttattt ttatagcgtt tgaatactgt ttcagcgaaa
    20041 cgaacgtaaa actgaataag ctttcgatta ggccatccac catattctgt aaccaaatat
    20101 aacggcattt cataatggga aagagaaacg actggctcaa tcccatattt tagacattcg
    20161 tcaaacactt gatcataaaa aaataatccc gcttcattgg gtgtttcttc atcaccatga
    20221 ggaaaaattc ttgtccatgc gatagacatc cgatagcatt taaaacccat ttcagcaaat
    20281 aaacggatgt cttctttaaa gtgatgatag aaatcatttc cgtgtctttt aggataataa
    20341 tacttgctgt tgggatcctg cgccgctttt acttgctgat gcgtcatcat atgccattga
    20401 tctgtccatt tttctttagg taaatcgctg tcgaatgtat acacatcaga cacagataat
    20461 cctttttcat ctacatccca tgcaccttca cattgattgg ccgctgtcgc tccgccccat
    20521 aaaaatcctt ctggaaattt tttcatatcg atccccctaa acttgctagt tttcttgttt
    20581 gattattttt cttatgacta gtaatgatat ttttgaatct actactattt gtaacaataa
    20641 ccattgtggt cggatcatat ccctctttga ttaattcttg caaatctact tccatcaata
    20701 aatcgccttt acgtactttt tttccatcag atactgcact ttgaaagtat ttgccattta
    20761 aattcactgt atcaataccg atatggatca gtatctctgc tccttcttca ctgactaccc
    20821 caattgcatg tttcgttgga aaaactgttg aaacttcccc gtttacagga ctgtagattt
    20881 ttccgtccgt tggaatgatc gcaaaccctt ctcctaaaga tccactagca aatgttggat
    20941 cgtttacttc agataaatca attatttcac ctgctgcagg agtacttaac actatatcct
    21001 ttgaggattc ttcttcgatt tcatccttgt agccgaaaag aaaagttagc atacaggaac
    21061 tgatcatcgc taagaaataa ctagcaacta gccaaacaaa tccttcacca atataaatcg
    21121 ggaaagacaa aatacttctt gtagcaactg ccaaagcacc ggctcctgcg gcaccagcta
    21181 ctccaccaaa tatagctcca catatacaag caatgtaaaa tggtcgttta tatttaagag
    21241 tcacaccata aacagcaggt tcagtgattc caaataatgc tgtgataaat gcagataaag
    21301 ataaactttt tactttctta tttttcgttt tcaaaaatac cccaagtact gctcctgctt
    21361 gcgcagctac ggcagtcata catgctggac ctagcgtatc acgaccgtag aaagaaagat
    21421 tgttggtcat tactggtaca agtccccaat gtaacccaaa aatcactaac acttgccaaa
    21481 atccgccgat aacagcacca gataaaacag ggctaaagtt ataaacagct aaatatccag
    21541 ctgcaatcag ctgacttgca taatctgcaa ttggacctac aactaataaa gtaattggga
    21601 ccatcacgat gatacaaatg aatggtgtca ataaatttcg aatactttcg tgcaagcttt
    21661 tgcgaatctt aggctcaata taagaaagaa cccatacagc taaaattgct ggaataaccg
    21721 tacttgtata tcttgctaga atcacgggca tccctagaaa tcgcaaggtt atgctatcac
    21781 tatatgcact gacaatcgta ggataaacga gagctgctgc aataaccata gcgatgaaac
    21841 gatctgtatt gaactttttt gcagcagtat atgccaaaaa tataggcaag aaatagaaaa
    21901 atgcatcagc tgctgcattc aaaatgatat aagttcctga ttcagtagtt aataaattca
    21961 aactcgtaca taaggcgagt actcctttga tcaaaccact tcctgccaag acgcctaaag
    22021 tcggggcaaa aacagcggcg atcatgtcta taaaagagtt taaaatgcct tttttctcag
    22081 ttcctctctt tccactagat gcatcatctt ctagtttcat ttgtttggat aatacgtcat
    22141 acacttcatt tactgcattt cctactacga cttgaaacat tcctccagct tcgactacag
    22201 tgatcacacc ttctagttgc tctaccttct ccttatctgc cttcttatta tcttttaggg
    22261 taaagcgtaa ccttgttgca caatggtaaa cattgctgac attttcttcg cctccgacaa
    22321 atcggacaat atctttcgct aattgtgaat agtccatttt tacttccccc ttgttaatta
    22381 atgccgtagc aatccttctt acaagataag tatagttctt agaaaacggt ttctccattc
    22441 aattagtacc ccttctaata gcgaacgaaa ctgtacaata gtgtgtatgg tttacttagc
    22501 cgagcaaatc actcactgct tgaaagaaaa caagtatatc gtttctctta tagtcaaagg
    22561 agacaaaaaa aacacgcttg atcttccttt gctgatgtat aagtggtatc tcaagctgat
    22621 actctgtgat ttttgtttct acttggcttt tgataagaca gcacaacaaa gtctcggcat
    22681 ttaacggaag cataactagg tcagaactag gagagattag ttgctgaatg gaatctatct
    22741 ttttatggat ttttatttga ttttcttctt tgtagtaatg atcaagcagt tttgttttct
    22801 ttttttcttc aactatggtc agcttttcac gcaaaatctg ataaatctcc gaagattcaa
    22861 actcatctag aacactaggt agataaatca aatcatccca ctcaaaaata agctcttgct
    22921 cagtagtcaa aattgcatca tattccgtta ttttgtttga ttgatttttg aaaagataca
    22981 ctggttctat ccggcattct ttgatccaca tgttcatact ttgttgaatc tgttttttta
    23041 gtgtattcaa aatactaatt ggctggttac taacaatcag tatctcccct tgttttcgaa
    23101 aaggattcaa cgcttcggca agatacaaaa ccaaataagc gctttcagct aaattgggac
    23161 gtaattgaaa atgtattggg aagaaacgcc gaattaaata aatttctaaa ggataacggg
    23221 agatgatctt ttgtacaaaa tgattcatgg tattatgtcc ggcatccatc ctcgttttca
    23281 tttgtttgat atgggttagc aaaaattctg tttcatggaa caataacgaa acaggaagat
    23341 ctaaaaaacg aataatcgtt tgctcaaatg ctcttagatt cttctctatt tctttgtttt
    23401 tttcatcatt aatcatcaaa taatttaact ctaatagtcg attttcaatt gcttgttttt
    23461 cttgattgga aaaagaatag ggtagttctg atgataactt ttttgtgagg gtctctacca
    23521 tcggaataaa taatgtatac ctgtttgttt tttctaaaag ttcttctctt cgaagaatgg
    23581 tcaaaacgag ataccgagaa aatcgtatga agtcctctcc tgaaacaata taattatatg
    23641 atataagaac ctcttttaat gtcttttgga cagtcggcat gatattggaa aaaattgtac
    23701 tgatttgttg aggcaacctt gcgtgttgga tcaccgtttc tgttccaaca agagataaga
    23761 aaattctttt tgaattttct tcagcaatga tttttagtcc ttttgtcgac gaaacttcca
    23821 gttctaattt aggattgcgc tcgatccaac gcaaaatcgt ttttatttgt aatgatacgg
    23881 ctgtttttga aagaaagaaa atgtctgcta tcttttgcat actgacatac cctttttgaa
    23941 acaataagta cgtcacaata gttgaagctc ggaaatccat gctggaatag attttatgtt
    24001 tcgtcacctc ttgtatgatt tgctgtttag tttcagattc aattgattct aaaaaataac
    24061 ctgaacgttt atttgactgg ataatgattt tcttctcgta gatagcaagc atatttttga
    24121 tttcagtttg gatcgttttc ttgttggtac ctaaagcttc agctaattct tcgcttgtta
    24181 tccaatgatt cttatttctt aatactacaa gaatttggag ttgtcgttta tttaagtcca
    24241 tttgcttaca cctcctcttt gttataaaca tacaggaaaa acctctcaaa tgacaatagt
    24301 cacttgcaga ggtttaaaaa tcatttgaag aaagatctat attcaaggtt tttaccatta
    24361 gactggataa tttgtttata atattcaaaa ctatcttttt tcaatctcct aaagcttccg
    24421 ctcccatcat tttgtctatc cacataaata aagccatatc gcttcctcat ttcccctgtt
    24481 cctgccgata cgatatcgat tggtccccac cataagtaac caatgatttg gcaaccatct
    24541 tttattgcct cagcaatttc ctgaagatgt atttttagat actcacaacg ttttggatcg
    24601 tggattcgat tcaattcatc tggtgcttca tctagtccaa tgccattttc aactatgaat
    24661 aatggtaatt cataacggtc tgtcaattca ttcatgacat aacgaaaccc tagaggatca
    24721 attggccaac tccaaggttc gggagatttt tccttcaaaa agggattatc gaaaccattt
    24781 gctccgccag tatctacgcg catttctgct tcttttttat agacagcgct acgataataa
    24841 ctaaatgcaa tataatctac cgtgttagct tgcaagtact gttcgtctcc atctaacatt
    24901 actggtgcac agtcttcttc cttccatatc ctgtaaatat aagctggata atgccctcgg
    24961 cacatgacat cggagaaaaa ccatgaattg cgtttaaatt gcagtgaacc aaatacattc
    25021 tctggatcac agtcatatgc ataagtcgct aatgcagaaa agctacacat aatacccatc
    25081 ttagcatttg gatcgatttt ctttaataat tgagtagcac gggcgttcgc tagaaacata
    25141 tgatgacagg cttgataaat ctcttttttt gttagtgtag caatgggttc aagtttatct
    25201 ctagcaggga atgtaaccaa tccagcagct gcataaggca tacgaaaagc attattgatc
    25261 tcattaaagg tcatccaata tttcactttc ccttggtagc gttcaaagac ggtctgcgca
    25321 taaaattcaa aaaagtcgat taattttcga ttttgccacc ccccatactc tcctaccaat
    25381 gctaaggggg tttcataatg actaagagta attactggct cgatatcata tcgatttaat
    25441 gtattgatta gtctgtcata aaatacgaga ccagcctcat ttggcttctg ttcgtctcct
    25501 cttggaaata ttcgtgccca tgagatgctt gttcgaaaag cttttaaacc taactccttc
    25561 agtaaacgaa tatcctcttc aaatcgatga taaaaatcaa tcgcttcatg agaaagataa
    25621 tggagtgatt cgtctaaagc aatctcccaa atcttttttt cttcattcca ctgaatacta
    25681 ggatgctggt tcatgatccc gataagcgta tctgtcacat taggtaattt gccgtcttcc
    25741 aaccatgcac cttcacattg attagcagct actgctccgc cccataaaaa attttctgga
    25801 aatatttcct gatccataac tatctctcct cgctatcaac aatttcttac ttgaagtata
    25861 gctcgattca tcaaaacaag atattctaac tatttcggca gaagagaaga aaaaaattga
    25921 atgctactct tcatttttaa tatttatata taacaaatac ataagacgat ccccgaaaga
    25981 aaacactcgt taaccatcta agcaaacgat ttattttact tccaacacaa atgcttcata
    26041 aggtcgtaaa tcaactttgc cgtctggtaa ctgtttcaga ggataatttg acacaataac
    26101 ccttaaagct tcacgtggaa cagtgaacgt ctgcttttca ctggacatat tacaaataac
    26161 gagccattgc tggtcttcat atatgcgaga ataggcaaag acatgctcag gcgtcttttc
    26221 cactaattca tagtctcccc agacgatgat gtcatgtttt ctacgcaaat cgatcaattt
    26281 cttgtacata taaaaaacag aatcttgatc tgctaacgct tcttctgcat tgatttcttt
    26341 ataatttgga ttgactcgaa gccatggaat tccagtagta aacccagcat gttcacgggc
    26401 gttccattgc ataggcgtcc tagcattgtc tcttcctttc gcattgattg attccaagat
    26461 ttcctctttt gtaaatccag aagaaatcct ttcgttatac atattgattg tctcaatatc
    26521 ttttgcttcc gcgatatcat cgattgggca attcgtcatg cctaactctt ctccttgata
    26581 gatataaggg gtgcctttca tcatatggag caagatagca aacatcttgg cactttcttt
    26641 tcgatacaca tcgtcatttc cccaacgaga aacaattcgc ggaagatcgt gattattcca
    26701 aaataaacta ttccatcctt catcacctaa agatgtttgc catttggata atactttttt
    26761 cagttcagag atactcaagg gtttcaaatc ccatttgtct ttgccttctt gctgatctaa
    26821 tcctatgtgt tcgaattgga agaccatgga taattcattt cttttaggat tggaataaag
    26881 tttagcgatt tcggtagttg ctccccatgt ttcgccaaca gtcatcagat ttttgtcacc
    26941 aaaagttgct tgattcattt cctgaagata ctcatgcagt ttaggtccat tacttgtgat
    27001 ttctttatcc ggttctttgc caatcatatc gatcacgtcc atacgaaagc caccaatacc
    27061 tttatcgatc cagaaattca tcatttgata aatctcttgg cgaacctgtt tatttttcca
    27121 attcaaatca ggttgacgct tgctatacaa gtgcagaaaa tattgccccg ttttttcatc
    27181 caactgccaa gcagaaccac tgaatattga gcgcaatcta ttaggctctt ttccattgac
    27241 cggatcacgc caaatataat agtcccgata aggattttct ttatttttac gggcctcaat
    27301 gaaccacgga tgttcatcag aagtatgatt caccaccaga tccatgatga tacggatatt
    27361 tcttttcttt gcttcttcaa tcagttcttc catttcttcc atcgtaccga attctgccat
    27421 gattgcttga taattactga tatcataccc attgtcatca ttcggagact cgtatactgg
    27481 agaaagccaa attgcatcaa tacctaaata cgccagataa tccaacctgg aaataatccc
    27541 ccgcaaatct ccaataccat cttgatttga atcttgaaaa cttcttggat agatttgata
    27601 aacaactgaa tggtgccacc atttttgttc catgattttc ctcctataaa tggatgtttc
    27661 tattttttgc ttaatcattt attttagtct ctctcactaa aaattgtaac gctttcaaat
    27721 agctattgca ccttgttatc ggtaacagaa taaaacaaaa aaacagctga ggaaattccc
    27781 tcaactgttt tttgaaagga ttgatttatt cagggaagaa tgctgatttc acaacttctt
    27841 tataaacggt gttcactcag ctgtccctcg gtattagctc aaaaaacggc aaaatataag
    27901 aaactatttt tttcgttttt ttctctaata ctcaggccag aacactgatt tcacaacctc
    27961 tttataaacg gtgttcactc agctgtccct tggtattagc tcaaaaaaag gcaaaatatg
    28021 aggaactatt ttttcgtttt tttctctaat actcaggcca gaacactgat ttcacaacct
    28081 ctttatttca cattcaatat ccacatgaat cccatgaata caaagaacag accatacatg
    28141 atgggagata cttcttttcc tcttttagct gctaacatgg taattggata gaagataaaa
    28201 cctaatgcaa tcccatctga aatactataa gtcaaaggca tgccgatcaa gatcaagaat
    28261 gaagggatcg caatctctaa gtttccccat tcgatttgtc gcaaagattg tgccatcaat
    28321 actcctacca taatcaatgc tggtgcagtt acttgtgaag taacaactga tagtaatgga
    28381 gaaaagaaca agcctaacaa gaagaaaatc cctgtagtaa tagctgtgat acctgaacgt
    28441 cctccaacgg cgataccagc tgatgattct acaaatgcac caacaggaga agtacctaat
    28501 aaggaacccg caagcatagc tgttgaatca gaagctaaag ctttccctac acgaggcatc
    28561 ttgttgtctt tcatgaaacc tgcttggttt gctaatccaa ctaaagttcc tgctgtatca
    28621 aagaaagtca caagcaagaa tgtcagcact acgacccaca tttgaagaga attgatgtcc
    28681 cctacatgtt ttaatgcaac taaaaatgtt ggtttcaaac ttggtgctgc ggcaacaatt
    28741 tcagaaggca ttggaatcaa acctgtgacc agacctaaaa tcgttgtagc tgccatcccg
    28801 atgaagatgc cacctggtac acgccgaaca agcaagatag cagttacgac taatccaaaa
    28861 atcgtcaacc aagtagaacc aacgttgagt gatcctaatc ctactaatgt agattcattc
    28921 gaaacgatga tcccaccttc gctcagacca aggaaagcaa taaatagacc gataccgcca
    28981 gaaatcgcat atttcaaatc tgctgggatc gcatcaatga tcatttcccg cagcttgaag
    29041 attgtgatca aaataaaaat caaagaagca acgaatacgc cggctaatgc tgtttcccat
    29101 ggaatcccca ttcctaaaca aacagaataa gcaaaaaaag cattgatccc aagagcaggt
    29161 gccgttccaa ttggataacg ggctaatacc cccattaaaa tacagccgat cgcactggct
    29221 aatgcagtcg cagtaaacac tgctccttca tccattccag aagcacctaa tacagttgga
    29281 tttacaaata agatataagc cattgagata aatgttgtaa atcctgccag tacctcacgt
    29341 tttaccgtgg tgttcaattt ttctatttcg aagtaggaaa gtattttttc cttcatcttc
    29401 catcccccta aatccgaaca ttataaataa agtccgttaa aatttcgatt tattaataaa
    29461 acaacgtgtt ttatcatata ctaaaacaaa acataagtaa acaaaaaatt cggattttaa
    29521 gcaaaatccg aacgttccat ctgattaaat ccctttatct caaagttcat gaacattcac
    29581 tttggattac aagaatttct ttattgtgtt aataaagttt cttcattcta gtctcaaaaa
    29641 tcaatagtgt gatttgattt taccatttcg tttctgttct tctttgatga attcttttgt
    29701 atcgacagga ttcagattat ttagtccgcc aaaacctgta tcgaccattt ttccccagcc
    29761 ttttgtcttc ttttttcctg atttgagatt ctttgctcga agcttctcac tatgttttgc
    29821 tcgccgatac ttcaaataac cttctaatct tcccattaga tccactgttt ctcctccttt
    29881 ttattcaatc agacgactca gcttttccta taacaaaata attgccttca gggtccgaaa
    29941 aattgaaagt caagacgcca ttgttgtctg tgatttctcc tggttcttcc atgttctcgt
    30001 agatagtttc aaattcatcc gtaaaaaata ctaaagaagg cggtggtcct aatacctctg
    30061 gtgaaaactt ctgcacaaat acttttggga atacgcctaa ttctaattct tttgagatgc
    30121 tgagtacaat actcttaaat tcttctggca attcgattgt ttcagaaatt tctgcaccaa
    30181 ttttttctac aaagaatcgg caaatcatct ctacgtcatt gacataaagc atcacacgtg
    30241 ttttttgtat catcgtttga cccttctttc tatttgattt tctttcctgt ctataaactg
    30301 attccattat atcacgaaag cgcaaacacc ttgtgtttga tactattcaa gaaaaataaa
    30361 gcaatagttt ctaggattgc tttcctccac aaactttttt tacaaaaaaa aaacggcaat
    30421 gaatgccgct cttcttattt cgattctttt ataattctgc ttctgattca tctttggtta
    30481 gtgtgtgtct aacactagtt acgccaaatg tttgatcgat tttttccttc aacgcttcga
    30541 ttgcctgtgc gccacgtgcc gcttgttcag cattgatgga ttcaatgacc agcaccgctg
    30601 cttgtgtttc ttccgtcagc atcgttcttt gggcttcacg ccagttgaga cagcgacaga
    30661 tcgctccttg ttcatcatag tagatgattt cttccggaag tgccggagca tcggaatctg
    30721 cacctaaagg caggaatgat tcgtcacctt gggcttttcc taaatgcaga tttcctgcga
    30781 tcttttcgat atcttctccg ccgcaaggta cgccaaaaga caaggaaata ctattataga
    30841 tatctacaag cggattgatt gggaaaaatt cccgttcttg atttgcacgt ttcagtaaag
    30901 cttcaataga agaacgtgca ccttttttag tcttgaatgt ggtaaatgcc tgacgccact
    30961 gagcaatgac ttcgttttgg ctgaatgttt cttctgtaag gtaatttctt gcttcttttg
    31021 ctgcctcatt caataattga tgatacgttt cttcactttc ttttgttacg tggttatcga
    31081 taccatttac ggataagatt tcgatggttg cttcaggaaa tacttcccag aaattggtat
    31141 ccactattac ttttttcatc tgttcacacc tcttgattag aataattgct tgatgaatag
    31201 atagtctgtt tggggatcat ctcccatata aaaaacatgt tcgctgtatt tgataaatcc
    31261 ttttttacga taaaaagcga gcgcaacatc gttgtgttcc caaacaccga gccaaatggc
    31321 tgttttttgc ttttcttttg ctttttcaat agctgtatct agtaaaaatg taccgatacc
    31381 ttgatgttta aatttttttc gtacatagat tcgctcgatt tctaaaaaat gatcagccat
    31441 ttcctcagat tgactcgttc ctgtatttag tttcaggtaa cccgcaggct cttgatcgat
    31501 actcactagg aaaaaatctg tttctttatc ttttagctct tctgtaagtt tttctagtgc
    31561 ataagcttgt gtcaagtaat cagctaaatg ctccggtaat tatcttttcc aaatgtatct
    31621 gtaaatgttt cgatactaat ttgttgtagt aagtctacat ctgaaggcgt catttttcga
    31681 atttcgtatt tattcacggc ttcttccttt caatagatcc ttttattgcc ttttttgaca
    31741 aaattccaat cttcgctaac attcttgcat actttattta aaagatattc caattgtttt
    31801 gcttcttcgt cagaaagacc atttaatgcg actgcattgg agtagttgtt ttctcgaatg
    31861 atgaaaggat agatttctgc tcctttttta gtcggataga gtttcttgat ttttttattt
    31921 tctttatctt ccaaacgttc gatcatccca ttggattcta atttcttgat tgctcgggca
    31981 gtcgttgtac gatctacttt gatcatttct gctagttttt cttggatgat tccaggattt
    32041 tcgcaaatac gtactaaata aagatactgt cctcttgtta aatcgacttc tttgaattcg
    32101 atattgctaa tagagtctag cgctcgggca atcattccga tgtctcgaag gatttcagcc
    32161 atttcatccc acctttattt tgtttgtaag actagtttac ctctttttgt tgcaaatgca
    32221 actattttta ataaaaaaat caagttcttt tttaataact agtaaagtat attcttttct
    32281 tcttttacga aaaagctcaa tcacaataga tctggttttt gttttctaaa ataagtaact
    32341 gtttcttcgt tgttcgcttt tctgatagct ttggcaactc ttctatacta aaaaatccca
    32401 tgttggaagt ttcattattc tcaataaact tggcctcttc accgtggatc gcacaagcaa
    32461 aaacaagttt ataatactga aaaagctgtg gaatatcttt ttgtttattc gtatcaaaaa
    32521 ctgctcgcaa ctgagtagtt tctactgtta atcctgtttc ttcatagact tctttacgca
    32581 cattttcttc aggagacaat cctatttcag caaatccacc aggaagtgac cattctttcg
    32641 tccgtttatc ttcgattagt aggaccttgc catctttttt gatataggca cgaacatcta
    32701 cttttggtgt tggatgtcct tctccaatcg ttgtgagcgc ttttatttct tcgaaagttt
    32761 cttttcctat ttcactgatc agttccaatg aaatcgtccg gatctcctca aaacgctctt
    32821 tatcaaatac atcttttcca taatatagac cagcttgaga aagtgcgagt agtcttttgt
    32881 attgagccaa cttcttgttc attctcttcc cttctttttt agcaaatgta tgactatgta
    32941 atcaagtata gaagactggt ttaattacgg caaataaata taatgaaatc tgcaataaat
    33001 aaaagaatgt taaaaaactc gagaacaaaa gacattcgac ttctctgggg ctgtgaataa
    33061 atggcgttca aaagcttgca tctgcggtaa taagccccat caaacgaaaa atatgacgag
    33121 ctattcttgt ctggctgttc ttattaattg aggcaggaca gctttttcac aacctcccca
    33181 ctaaacggtg ttctcctacc aactcctcgg tcacaagtca caatattcat caaacatgag
    33241 aagctgtttc tttgaaattg ctccttgtga ctcggagctg aacgacaggc tcacgacctc
    33301 tcggtaaacg gtgttcaaaa gccaattttt cgatattaag ccatttcttt gttacttatt
    33361 gtcattgatt tctttttcta atttatccaa tagtggagtg taatccactt gagtatagtc
    33421 tgttacatca aattcatata gtgttcctaa ctggaatttg tcatattttc ggtcggcgat
    33481 gatctttttg aatgcttctt tcgtaatatg attggtccct ttcgttcgat cttccaatac
    33541 gtcaccatag tgataatgat ccatgatata gctcaaatga cgatctgatt cacgatcacg
    33601 tttgtaccga cgttgccata acacttcaaa gtctgctgtt aggcgaatcg tgatcacctg
    33661 atatccgtat ctatctgcta attcttggag tcgtgctttt tgcttatcac taaaaggata
    33721 ctcggacaca atcactttct ttcctgcttc catatacaaa tcaagtgctt tgtaatagaa
    33781 aggataaact ttcgtccttt cttgttccgc ccgttcttcc aaattgttaa acccgatgga
    33841 ttctgcatag tattccttga tttcatcgag cgtgatggca tacatatctg gaaatcgttc
    33901 ccgtagttta ttcataagat atgtttttcc tgtaccagga ctaccagcca gaagaatgaa
    33961 atactttttc atctcattta tttcctaagt taattggact ttccaagttc ataaacagtc
    34021 caatcttatg cttgacaatt tcttttactg ctttatttgc tggaatcaca ttatggcgaa
    34081 gagacttgtt gatttctgtt tcactaaagg tttctttagc tactttcgtc cagttgacta
    34141 aaagctccgt tccaacattg aatttgcgga tcccgttatt gatcaattca ggataatctt
    34201 cttctttcac acctgttcct ccatggataa ctagggggac atcaactact gcatcgattt
    34261 ctttcagcaa gggaatgttt acttctgttt ttgatttgaa ttgtccatga ttcgtaccga
    34321 tagcaatagc taatgcatcc acgcctgtag cttctacaaa tttcactgcg tcttccggtc
    34381 ttgtatatac cttgtcattt tcagcgacat ggattccttc ttctgtaccg ccgattgttc
    34441 caagttctcc ttctacggaa acaccgtgcg catgggcata ttctactact gcttttgtct
    34501 tcaagatatt ttctttgaaa ggtagatggg acccgtcata catgacagaa gtatatccgc
    34561 tatcgattgc ttctttgata tcatcaaagt ctcgggcgtg gtctaagtgt aagactgcat
    34621 caaccatttc ttcttctgca atagctgtca ttacattgac taacacatgc atgccgatat
    34681 atttagcggt atcgacactt gtttgaataa tgattggcga acccatttct tttgctgcgc
    34741 ctagcatggc aggaagcatt tctaggttat gcgtattaaa agctccaact gtaaaattca
    34801 actcttctgc tgtttttgtt acttctttca atgttgtata catcttttat tgccacctta
    34861 tctttttatt tgtttccttt gatcgttact tgttttgcaa tttgtcgcat ctcatccatt
    34921 ttgcccatgt agtaatcgat cccttgatca tcaccagcac gagcagcatc tgcacgcttc
    34981 tggttataga ggctcatcag ttttttatac ccatctccga tcgtctgttt attttccaag
    35041 ctcttttcta aatattggat ggcttgatcg ttctcatgca attcagaaaa tttaagtcca
    35101 acttgttcat aaagttccgc taatttatgc ctatcttggg tagtggaaat ctcttgtttc
    35161 aattgtgtaa tctctgattg aatcttttcg gtcgcttctg gcgatagggc tttttcttct
    35221 tttgccagaa cttttttcgg ttctttttct tttttcttaa aaaatccaaa catcattttc
    35281 cctactttca attaaaacgc tttcaaaact gggcttaaga tccaggcata taagagtgct
    35341 gcggctactg tatctacatc ggttgctgta gcattgatga atcccatcga attaaagatc
    35401 gttactagca aagcgggcaa taatgtaata aagaaaccat gagcaatacc gccaatgatc
    35461 gctcctcggc gtccgccaac tgcgttgcca aatatccctg ctgtccctcc ggcaaagaaa
    35521 ttggttagca taccaggtaa aatcatcgct aagccgaaca tgggcaaagt aaacatggca
    35581 ataatcgtac caatcgttgt cgtaatgaaa cctaaaatga cggcatttgg gctataagga
    35641 aagaaaactg gacaatctaa ggcagggatc gcatcaggaa ctaatttcat agctatccct
    35701 cgaaatgccg gcacgatttc acctaacagt agacgtacac cagctagcaa tatatacaca
    35761 cccactacga attggatggc ttgtaaaaag gcaaacatga tatagttttg atctcctgat
    35821 aattcagaag cgaatggttc gcctgcaaat aaaacagtga tgatatatag cgggaccatc
    35881 acgaccatga cagacaaata agtatcttgc agaaattcga aatgtgtcgg caacttgata
    35941 tcttcgatcg actttttatt ttcgcctttc tcaccaaaaa gcttagcaac accggcttca
    36001 aataagtacc cgatcgtaca aaaatgacct aaagcaatat catttgatcc agtgatttta
    36061 cgaatgatcg gttgcgctac tgccggcata gcaatggcga aacaagctcc gataaaacca
    36121 ccgaccaaga tcaatacgat ccctcgcaga ccggcaaaat agccaaagac tgtcgtcatc
    36181 gttgccatcc ataaaattgc ttgaccagtt aaaaaaatgt acttccattt tgtgaaacga
    36241 gccaaaataa tattgaatac aaaaatggct aagaacgtca gtgcaatatc tctacctaaa
    36301 cccaaatcat tcattgcttg atcattgata gattcaatag aagggatgat cccttgcata
    36361 tgaaatcctt cagtaaagat tttcccgaaa taagttaaac ttccaacgat gatgctcgaa
    36421 ccggcactca atacttgaaa tcctaggagt gtttttaacg tgccagagat gacttgtcct
    36481 gctgatttct tctgcagtag tagacccaac atagcaatca atgcaatggt gatcgatgcc
    36541 tgagtcaaaa tattttcgat gataaaattg ataacgctca tgtttttacc ctcttttctt
    36601 tttgtattta gataactccc ttatcttgca gaactggggt gattttttct tcaatttcat
    36661 tttttgaaac aatatttttc aaatagatca tcgccgtttt aggatcaact gcgaactttt
    36721 cgaactgcga acgaaaattt tctgctgtga tgatcacatc tggtttcatg gaaactgcgg
    36781 aagaaatatc acaatggtcc agtttggctt ctactcctaa tttgttcaaa acatcctcag
    36841 cagacatctg tgctgcaaaa ctacttccta aacctgcgcc gcatacgaat aaaatgttca
    36901 atttgttcat ctttgttctc ccccgtatca tttattattt ctcaactact gaaaaaagca
    36961 gttgtttgaa atcttcgata tttgtgcatt caatcaatcg atccaacttc tcttcgttgt
    37021 tgatcaattc aattagttct ttcatgatgt tcagatggga gtaggagtct actgctgcca
    37081 aacaaaaaat aatctttact ggatccattt caggattacc gaaatcgatt ggttgctcaa
    37141 tcgtagctac gctgactcct aatttattga ccccatcttc tggtcgggca tgggctagtg
    37201 ccatgtgttt gccaatcacg atatacggtc cgtaatcatt cactgcacga atcatcgctt
    37261 cgacatagcg ctcttcgaca atgttttctt taaccaatgg tctagcagct agttcaatcg
    37321 attcctccca agtagtggct ttttctttga tcatgatatt gctgtccgtc aaaatatctt
    37381 ttaacatagg ctggatctcc cttttgttga tttctaaatt gtttgtttcg aataattttt
    37441 ctaacttgcc atagatgatt cgatctactc ggccaccact ttctttcatg acatctatta
    37501 tttgagtgaa taactccgtc gattcatgac tgttaggctc taaccgctgt agttcttcat
    37561 ttcttttcaa aaagtcttct ataaccaaga tattcgtctc agttaaaatc ggatcgacaa
    37621 ctaaaagcgg cttatttcga taattcaatt gaaaggtgct gaaaaccaga ttgacatcca
    37681 atttatctac taattcgatt tcttttgaac ttaaaactgc agtaatctcg atctgaggaa
    37741 acttttcttt cagattctct gctaacagat ttccagtagc catcccatgg ttacagacaa
    37801 cgactgattt ataaacataa ttcaagtctc gcttgattac actggcgatc gtcgaaaagt
    37861 ggatgacaag aaaagctatc tcgtcctcca gtatcttgcc accaattact tcttcgatcg
    37921 taggaacaaa atgagtgact gcgcggtaga ttgggaaata atttgttcgg atgttttctt
    37981 tcaatggatt catgacttgg atatgattct tgattcttac aatcagtgca gccatgtgct
    38041 tatagagatt ttcgaataag gcttcttcct ttagatggaa aggtacgtgt gtctcgttct
    38101 ctacaaattg gatcaattgg atcgttagta attgagcttg tacccactcg attgaattgg
    38161 agatatctct agcattgaac gtctcaatag tgaaacgaag ataatttctt tctacttgcg
    38221 ggacattgtc caattgaaat tcctcgatca tgtggtcaat aaatgcagaa aagctactgt
    38281 cttttatttc tgtatttttc caattaatgg cagagataaa ttcatgtttc ctgattcgct
    38341 ggatccagat caatgtaaaa agcaggattt gttttttata aatatcatct tcttgtttca
    38401 acaacttatt ggaatagatc tcctgtattt ttttgatttc ctccaaagga aaataatgga
    38461 gaaagatttt ttgagccggt gttaattgtg catcttgatt cataaagaag tcggtcattc
    38521 ccagattctg attgataaaa tcatagatca tcgtacggat agatcgttct gaacctttat
    38581 aaaccagtcc ttgctttcca taactgacga tctctatccc ataactgacc agtgttgctc
    38641 gtaaccgtct catatcttca tctaatgtac ttttagagat ttgaaattct tcttcttttt
    38701 tgtttagatg gatcgggatt cggctgtaag caacggctaa aactagatca aaaatacgtt
    38761 cgcgccgatt caaaaagccg tctttcacat cttttatttc agtttctaat cgagcttgct
    38821 tttccttttc cagcttcaac aaaaaacctt tgttgcgaat tgtacggatc tccggaagct
    38881 ttttactgct caaccagata ttcgcttcaa gaacttcctg acgaatcgtc cgctgactga
    38941 cattgaactc acttgctaga tgttttgctt ttactggata ttgggctgtc atgattctgt
    39001 gaagtatttc aattgttctt gttttcatag aaatgatctc cttctgattt caagtatatg
    39061 gttccgctta cataataaaa agtagatatt tctgccactt gaagtggaaa gaaagtaagc
    39121 aaagcaaaca aaaaataagc catatgcttt ttcatctcct caacgaaaaa gacatacgcc
    39181 tattattaca aaaattttgc ccatctatac aaaaaagagg ttgtgaaaaa gctgtcctgc
    39241 atcaagtaat aagaacaact aaactaaaat agtgcttcct attttttgtt tggttgttct
    39301 tattatcgca gatgcaagct tttaaacacc atttagtgga gaagctgtga cagagatgtt
    39361 cagccttgag cgataagaag cgattttgaa aaatcgcttc ccatatttta caaaatcgtg
    39421 ccttattgcc gataggctat ctctggaaca ccgtttattc agaaaaagga gctgcgacaa
    39481 ggcttttgtc acaactccgt tcataaatat ttcctgtcaa tccagcataa tcggttgaat
    39541 aaaatcggct tgccatcttt tttctttctc agaaaaatca aaataccata tctgagaaaa
    39601 atactgtcgt tgtgtcttac ttcctgagat caatcgccca tcttttcgat cgactgaata
    39661 atcacagcat ctgaaatcaa ttcggatggc aaaactattt tcgtggatct gtcgataatt
    39721 tcctacttcc tgaatagtta tttttttagt atgatttctt acaccgtctg ctttgttttt
    39781 ttgcagaact ttctgatgtt cggcaaacag cttgtctgta taacagcttc tggctttttc
    39841 aggagtttct tcttcccaag cggattggat cttcatgaat atcttttgga tttccaaaaa
    39901 ctgtgctttc ttttctttag ccgttcctga catgcgggac aatatctccg atttcagcct
    39961 tttcttttgt cttttattct tgacgataga aaaagcagaa acccctccta ctgacaaaac
    40021 agctaatgca agaaaccccg tttgctcata actagaagga cctgtacttg gaccataata
    40081 cccataagaa tctctgccgt aagaacgact gccaaaataa ctgcccccat atgaacgacc
    40141 gccaaatgaa cctctgcccg aacttcgacc gctagatgta cctccaccat gaccacccgc
    40201 gacagcgaat ccttgggtcg gcagagcaaa caaacatagg cccactaaca aaatgattgc
    40261 taaataattg attttttcat tgtcttcctc gttatctttt attacaaaaa actattttta
    40321 tcatagcctt gctaaaagga agagtcaata accagatgca taaactgttt ttttagcaat
    40381 tttgtcttat ttagtcattg agtaacatcg gacagatgta tgtgtcggca gtccataatt
    40441 cctctatctt cagcatgaac aagcttgcag acaagagatc tgcgcttcct ccaggagaga
    40501 tttggttttc ctgacaaaag tgcaacagtg ctgtaaatgg acgatttggt aaagcacttt
    40561 gactagcagc atgagcaagt ttttgcattt ccactaacgt tttctgatca ctgcgatgca
    40621 atacgcatgt gtcatctagc gaactcatca aaactaacaa catatgcatt tgtttctgta
    40681 catatgaatc attatctagc tccttagctg cttggattgc aagcctgata tgcggatacc
    40741 ctaatatcgc ttcttcatat gcaccattta cgccatattt ttgcttcacc ctatgaccat
    40801 gagtggtttt tttatgacga tattttgtat caggaaaagc agcaagcttg ctgacatcat
    40861 caagtatttt cgataaagaa aaaggctgtt ccatactgat tttttgtgca atgacactga
    40921 tcaatagccc cattgcccaa atcgctcctt tatgggtatt gatgccattt gtagcaatca
    40981 gcattgcctt ttccgctttt cgcccaatct cagcaattct ttctcttaac tcctgatcaa
    41041 tagcataatg ccatgctatt tgagccattt cttcaaaaaa aggagttagc gtcttagcag
    41101 acttatccaa aatgcgccga ccttctttta cggcttttgc gatcgtatgg aaattatcat
    41161 ctcctaaaac catatcagct gcctgtttgc ttacttcact acctttgatt cccatagcga
    41221 ttcctatatc ggctcttttc aaagcaggtg catcatttac gccgtctccg gtcattccga
    41281 cgatttctcc atttttctgc aaagctttca cgattcgcag tttgtgttct ggtgtcgttc
    41341 gagcaaagac gtcgactttt ggtacttgtc gaatcaactc ttcttcagac ataagatcca
    41401 aatcgatccc ttctaaaact ttagcagtat gttttaagcc aatttgttcc gcgatcgctt
    41461 ttgctgtatc tttgtgatcc cccgtaatca ttttcactga gattcctgct tgttggcatt
    41521 cctttacagc tttgactgca ctttcttttg gcggatcaat caacccagca atccctgcaa
    41581 aagttaattg ggttaaagac tcatgcgtga gttcctgttt cgaatctact tttttgtaag
    41641 caaatcctaa aacacgctga ccttttttcg caaacgctgt ggctgtttga ccccatgctt
    41701 cttattctga agaagaaaga gttgatttag ccaataatac ttctggcgca cctttgacgt
    41761 aaatcacccc tcctttttcc tccgcatgca tcgttgccat atatttgtat tcagagctga
    41821 acggaatttt tgcttctatt tttttcaaag gcagatcggc tgtttcggtg tggcgaatca
    41881 gtgcaagttc tgtcggattg ccacttaaat tttctgtttt ctgttcttct ttcgtcttta
    41941 attcctgaca atttttcata ataaacagta cgcgagtttc ttcctttgct gctacatcca
    42001 caactgtcat ttcatttttt gtcaatgtcc ctgtcttatc tgaacagatc actgtcatag
    42061 aacctaatgt ttctacagaa ggcagtcctt tgatgatcgc cttttctttt gccatttcat
    42121 gtactccgac agataggatc atggtcaaca cagctggcaa tccttcgggt accattgaca
    42181 ccaccaaagc gatcatagct gaaagaagga tatgccaatc catgccatag cggaatgttg
    42241 taaaaacaac taagaacaag atcaaacaaa gaatgccttg aaaaatttgt ttgttcaatc
    42301 ggttgatctt cttgatcaga ggcgtcgttt gttgttcgac cgattgcagt gcttgattga
    42361 ttttaccgat ttctgtcgtg tttcctgttt ctacaacgac accgactgca gaaccagatt
    42421 gtacaagcgt tcctgaaaaa gccatatttt tttggtcacc gattgattct tctgctgcca
    42481 aaacggaatg atttttttca gatgcttctg attctcccgt caaaatcgat tcttctacta
    42541 gtagatcatg tacttcgatc aaccgaacat ctgctggaac gacgtctccg gcacgtaaga
    42601 caatgacatc tccttttact agttctttcg cagggatttt ttcttgcatc ccgttcgata
    42661 gtactatcgc ttcttgtccc atcagctgct tcaaaccatt caacgattct tctgcttttc
    42721 tttcttgcca ataactaacg agtccgttga cgatcactac gaataaaata atacttcctt
    42781 cgatgtattc gctcgaagca aatttcaaaa aagaggcaat gatcaacacg atcatcagca
    42841 gatcagtaaa gtgttttgct atttttttcc atcgttttgt ctgctgtctt gcttctatct
    42901 cattatatcc ttgatcagtc aggcgtttct gccgttcttc ttgcgacaag ccttctgttg
    42961 atgtttgata gtttttcaat acatcttcta ccgtcaatct gtaccagttc atcctatccc
    43021 ctcctgttta attgatactg ttattatacg cagggaagtt ttttcaggcg tatcgattat
    43081 ttcagggggg tctgaaataa ttcgttttgc agaatgtatc tgggcctaac tgatatttct
    43141 attgcttatt cttttatata caaaatttaa gaatacaaac cagataacca ataaaaaagg
    43201 aataaagcgt gtcgtgcttt cgaataacaa gctgaaagca attgaagtaa aaaacaccaa
    43261 caaagcaaga tctttatatc tttgtgtagt gttccgtttc ttttctttaa taaattgaac
    43321 atgtgcacac aagatcgaag accacacaaa tagaaaacaa ctcgttgtca tgcctgccaa
    43381 aagctgaaaa aacaatcgac tatcagctac aaaaaaatgt agacaaagac cgacaaaaaa
    43441 taacatccct gtaattaaaa taccgtgtaa aggtacgcct ttcttagaaa gcgcacaaaa
    43501 ccaatggggc aaacttttct cttttgctgt ttgatataaa atcctgctag tactgtagac
    43561 tgcactattt gctgaggaca aagaagcaac caaaatcatt agattgacaa ttgctgctcc
    43621 gctttggcaa tggatcactt gcagcatagt cactaaagga ctttctttta aatctaaaca
    43681 atgccatgga acaacaaata aaatcgacaa aatcgttcct atatagaaaa agaggatacg
    43741 ccaaggcaga cagttgattg catttttcaa attcttttgt gggtcactcg tctcaccaac
    43801 tgttaatccg atcatttcaa ttccagcaaa actgaataaa accataggaa atgaagcaat
    43861 cattccagca aagccaaacg ggactaattc attgagctgt ccaaaatttg ctttgattcc
    43921 aatagactgg gtatgaaaat ctgagacact caatcctata cccaataaga taaaaaggaa
    43981 aatccccaag atcttgatga ttgagaaaaa agattccaat tcaccaaacc acttgactgc
    44041 aacaaggttg actgccatta agatcattag tgcgctacct ccgcttatca aagctggtac
    44101 atgtacaaac cagaaatgga tatacaatcc tattgctgtt aattccgcaa gtccagctcc
    44161 aagccagcaa agccaataag tccaattgac aaaaaatgcc cactttttgc ctaaataata
    44221 gtcaacgaaa tcactgatag agttaaatgt actatttgct aaaaataaat cacccatgac
    44281 ccgcatcaaa ccataaatag ccaaaccgca tatcaaataa acgagaataa cagctggccc
    44341 tgctgatgca attgcctttg ctgaacctaa aaataatcct gttccaattg cgccacctaa
    44401 tgcgattaac tggatatttc gattagttag agtccgtttc attgccggtt tttccatcaa
    44461 gttcaccttt ttctttttca agcagcatgg cgacttcctg ttcccaagaa ggtttcttta
    44521 ttttttcaat acagagtggt actacaaaca aaatgacact gatggctgtg actgcaatta
    44581 gattgatcca tgtcccagct ttcatcgtca gtccgacaga aaatccgatt gccgcaaata
    44641 aaacaataac gacagtccaa actccaagat tgctcttttt ctcttttttt ccaattctaa
    44701 atggtcgatt caactttgca tgtgtataac gcaatctcaa aactgcgatc cccatgatga
    44761 catagacgat acagtagata acagtagttg aatttacgag catcaaaaat gcttgattga
    44821 cgccaggaat cagcaaataa aaaagtgcaa agattgagat aatgacagac tgagtcaaaa
    44881 taacggattt ggatacgtca aattgattcg tcttccaaaa attgaatttt ggtggatacg
    44941 caccttttct agcactttct gtcactgtct ttgctggtcc tgaggcccaa gcagataatt
    45001 ggactgctac accaatgaag acaagtaaac taaacagatt cacaataaga tgtggcaaac
    45061 caagaatttg gcaataaatc gaaatagatt gcgcgatatt attcaattcc atttgtcctt
    45121 ttggtacgac atttgctaca actaaagcat tcaaaatatt gacgaaaaat ataaaaatta
    45181 acgcggcaaa tactccgcga atatacgttt taactggatt tttcaaccga gtgatataca
    45241 cagaggacat ttcgatacca gtaaaaataa acatgatcgg cgcaaaataa acaaatgagg
    45301 atgcagtcgt agtatctggt attaatttgt cccatgaaaa actgcctaat gttccggttg
    45361 gtacgatccc aactttgatc cacgcagcaa accctaataa gagcatcatc gtcaaaggca
    45421 cgtacaatcc taaccaaaca ccgacttttc cgccgatttt tgccatatca aatttcaaat
    45481 tcaaaaaagt gatgatccaa taaacgacta aaatgacaac taatgtaaat ttgctgttca
    45541 aaccaagcgg cacattatcg ataatattac caaacaacgg agcaagtgct gaagcgacca
    45601 tcaccatccc aggaaacatt tggacccata acagccatga gacaacgaac ccccattttt
    45661 ttcctagagc attcgatacc caaagttctg gaccaccttt ttggggaaac attccggcaa
    45721 attcaccaga gatcaatgag attggaaaag cgtacaataa tactgcaacc agcatgtaaa
    45781 aaatcatcgt ccagctcgtt gctgctacat ctggaatatt tcgtacactt gctacaaggg
    45841 cgcaggtcat tccgataaag gtcatggtcg tgatttgctt tgatgaacca gtatctttca
    45901 tctttattcc ttctttcaat agcgacatat gtttttgttt tcttttattt ttgttcaaga
    45961 acagaaatga caaggtttca tcgattcagt acaaaaccca gtatcaccga aacatccatt
    46021 gaacgatctt agtgaactgg gtttgataca tgaaacgaac gatccaactt atagaacgtt
    46081 ttataaaaaa gaatatcttg gcgaggaata tatgaaaaac agggggaaat acaattgttt
    46141 tgatgaagca aataattgtc tgttctccat atgtctcttg ttattctttc acacaaaaat
    46201 cagttctatt ggatgatttc gtttagtttc ttttccattg ctttggcgat ttcttttgta
    46261 taaaaattga aaattcgatc atcattcaaa taaggagtca tgatagccgc acgtagcaga
    46321 gtgattttct gttctttttt ccattcttct ttcgttagac ccattctttc aacaaaacga
    46381 atcggagaat caccgtaatc ttcttgtgta aatgtagtat gagaagtaat aaaccgttca
    46441 ccataaacat cgccatccat ataagaagac cgatcgaaca ttttttcatt taattcattg
    46501 atagcgttca aatctgtaca gccttgttct ttgaataccc aattgaccat attaaaatca
    46561 ggatgattca atggatagac ttcgattgtt tttcctttaa cagtaaaagt cagatgatcg
    46621 agaaattctc tgaatctttg agctgcctcg attgaagccc caatcaattg accatatccg
    46681 gtcacattca atggcaatac acgatgtgct gtccagactg cggcggcggt tgctccagct
    46741 tttgatcctt ccaaaatata agctcctaac atatctggag cctttactga tttttcaaac
    46801 acatatggcg cgaaataaga aatgatattt ctcatatttt tatgtttgat tacgattcct
    46861 ccagcagcat aagggacata gcccatctta tgaggatcta tcgtgacaga atccgcttct
    46921 gaaatagctc tgaacccttc atatacctct ttgtcaatcg ttacgcagtg gtggaaaaca
    46981 tgatgttctt caaagaattc agctaaggaa gcatacggca caaattctcc tgcttcgttt
    47041 agaaacagtg aacgcgcata gccgccatat gcggcatcaa catgtaaata gaaatagatc
    47101 ccttcatctt ttaacctttc tcttaattgg acgattttat ctacactgtc tacttgacct
    47161 tcttctgtcg ttcctacgac agcaaccaca cctagaattg ggattttttg ttcagctaat
    47221 tcacgaattg ttttttccaa agcattaata tccattcgat aatcctcttg aactgggata
    47281 gcaaccatct gatctaagcc tactccgcaa atatctaacg ccttcatcca agaatagtgt
    47341 tttgtttgag gcaccagcca tttccctaat ctttggatat tttttccgct acgggaagaa
    47401 gctgctttga cctcatccat ttcttcgtcc gtaaagcttt cggtcatttc caaaatttct
    47461 tcaacagata aattcaaaag ttcccactca gacatttttt tcacttgttc aggcagcact
    47521 tccttgacag ctaaaggaat cgatttgatg cagcgggcgt accataatcc ttcaagatta
    47581 gcaatagaac catctgctgc aatgtgtccc catccgtctg tcatattgaa taatgaagca
    47641 aaatcctgtc ctacttctgc ttccatttgc gaagttgcca tagaagattc caatgcaaca
    47701 ttatttgggt tccacagcat cgcatagttg taagctaata aagcaggcat caatgtttca
    47761 gcattcattt gtccccagta acggcctgct gaatgccatg ggatcgatcc tgcgcgtaat
    47821 cgctgactga cttcatccaa gacctctatc atatggtcgc gggtggctag ataatctgga
    47881 gtgagcttat ctccttcgct aattgcaggc atatctgaag gaatataatt ttctctccat
    47941 ccaagatgtt catctaccat cttgttcaac aacattttat aaactggtcc attttcagct
    48001 ttgtcgccta taaagacggc cttgatatcc atatctttca tttttcttcc ctccatattt
    48061 tgttggtcaa tgtctcgcag atacatgtgt ttatctgtaa cacctcttca ctatagcgcc
    48121 aaaaatgaga aatttttttt tataacatca aatccacgta gatttttac
//
LOCUS       DACDLM010000016        45201 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.016, whole genome shotgun sequence.
ACCESSION   DACDLM010000016 DACDLM010000000
VERSION     DACDLM010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 45201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45201
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.016"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            162..803
                     /locus_tag="IV356_000921"
     CDS             162..803
                     /locus_tag="IV356_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP9014627.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            834..1538
                     /locus_tag="IV356_000922"
     CDS             834..1538
                     /locus_tag="IV356_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HAP9014628.1"
                     /translation="MKKNMDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKG
                     EETKIEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSE
                     HIINGKQEDIEFHFVHMNSKKENLVVGVMYQLMEQEGWLYNQENGESWNLEKHEHWVN
                     PDVFFPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQDFLLPFDGQYARPNNRPI
                     QPLNGREIYYFEEFEQ"
     gene            1535..2437
                     /locus_tag="IV356_000923"
     CDS             1535..2437
                     /locus_tag="IV356_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP9014629.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQLG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     LDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2595..4301)
                     /locus_tag="IV356_000924"
     CDS             complement(2595..4301)
                     /locus_tag="IV356_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin/fibrinogen-binding protein"
                     /protein_id="HAP9014630.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIAELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFHRLSQTELEPKAIQRQFQGIGFDTAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKNFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRDGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTEYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            4491..5114
                     /locus_tag="IV356_000925"
     CDS             4491..5114
                     /locus_tag="IV356_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014631.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIRQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            5564..6613
                     /locus_tag="IV356_000926"
     CDS             5564..6613
                     /locus_tag="IV356_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP9014632.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDVLIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVA
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            6610..7491
                     /locus_tag="IV356_000927"
     CDS             6610..7491
                     /locus_tag="IV356_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9014633.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            7494..8264
                     /locus_tag="IV356_000928"
     CDS             7494..8264
                     /locus_tag="IV356_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP9014634.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCKEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            8543..9397
                     /gene="aroE"
                     /locus_tag="IV356_000929"
     CDS             8543..9397
                     /gene="aroE"
                     /locus_tag="IV356_000929"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HAP9014635.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            9575..10657
                     /locus_tag="IV356_000930"
     CDS             9575..10657
                     /locus_tag="IV356_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAP9014636.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGGIDRISVPVDGSWNYG
                     QSDYAGSILEIDNQMNQSAITDFLNK"
     gene            10774..11184
                     /locus_tag="IV356_000931"
     CDS             10774..11184
                     /locus_tag="IV356_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAP9014637.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            11358..13586
                     /gene="topB"
                     /locus_tag="IV356_000932"
     CDS             11358..13586
                     /gene="topB"
                     /locus_tag="IV356_000932"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP9014638.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            13724..14041
                     /locus_tag="IV356_000933"
     CDS             13724..14041
                     /locus_tag="IV356_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014639.1"
                     /translation="MKKVHSFLNYLMGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAY
                     SPTLILSTLTAGAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQ
                     YFG"
     gene            14201..14437
                     /locus_tag="IV356_000934"
     CDS             14201..14437
                     /locus_tag="IV356_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAP9014640.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            14434..14832
                     /locus_tag="IV356_000935"
     CDS             14434..14832
                     /locus_tag="IV356_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HAP9014641.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(15499..16443)
                     /locus_tag="IV356_000936"
     CDS             complement(15499..16443)
                     /locus_tag="IV356_000936"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAP9014642.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(16739..17683)
                     /locus_tag="IV356_000937"
     CDS             complement(16739..17683)
                     /locus_tag="IV356_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP9014643.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            17904..19118
                     /locus_tag="IV356_000938"
     CDS             17904..19118
                     /locus_tag="IV356_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP9014644.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            19140..21155
                     /locus_tag="IV356_000939"
     CDS             19140..21155
                     /locus_tag="IV356_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HAP9014645.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(21238..22611)
                     /locus_tag="IV356_000940"
     CDS             complement(21238..22611)
                     /locus_tag="IV356_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAP9014646.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(22637..22921)
                     /locus_tag="IV356_000941"
     CDS             complement(22637..22921)
                     /locus_tag="IV356_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP9014647.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(22923..24938)
                     /locus_tag="IV356_000942"
     CDS             complement(22923..24938)
                     /locus_tag="IV356_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAP9014648.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKTLLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(25117..25422)
                     /locus_tag="IV356_000943"
     CDS             complement(25117..25422)
                     /locus_tag="IV356_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HAP9014649.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(25511..26542)
                     /locus_tag="IV356_000944"
     CDS             complement(25511..26542)
                     /locus_tag="IV356_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HAP9014650.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            26749..27624
                     /locus_tag="IV356_000945"
     CDS             26749..27624
                     /locus_tag="IV356_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP9014651.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(27776..28618)
                     /locus_tag="IV356_000946"
     CDS             complement(27776..28618)
                     /locus_tag="IV356_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP9014652.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(28710..30587)
                     /locus_tag="IV356_000947"
     CDS             complement(28710..30587)
                     /locus_tag="IV356_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAP9014653.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(30584..32005)
                     /locus_tag="IV356_000948"
     CDS             complement(30584..32005)
                     /locus_tag="IV356_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAP9014654.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(32008..35397)
                     /locus_tag="IV356_000949"
     CDS             complement(32008..35397)
                     /locus_tag="IV356_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAP9014655.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNEVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            35654..37045
                     /locus_tag="IV356_000950"
     CDS             35654..37045
                     /locus_tag="IV356_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP9014656.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNGRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(37118..37765)
                     /locus_tag="IV356_000951"
     CDS             complement(37118..37765)
                     /locus_tag="IV356_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP9014657.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(37773..38459)
                     /locus_tag="IV356_000952"
     CDS             complement(37773..38459)
                     /locus_tag="IV356_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9014658.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(38465..39538)
                     /locus_tag="IV356_000953"
     CDS             complement(38465..39538)
                     /locus_tag="IV356_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAP9014659.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            39760..40434
                     /locus_tag="IV356_000954"
     CDS             39760..40434
                     /locus_tag="IV356_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP9014660.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            40439..41779
                     /locus_tag="IV356_000955"
     CDS             40439..41779
                     /locus_tag="IV356_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP9014661.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(41928..42914)
                     /locus_tag="IV356_000956"
     CDS             complement(41928..42914)
                     /locus_tag="IV356_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HAP9014662.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            43638..44669
                     /locus_tag="IV356_000957"
     CDS             43638..44669
                     /locus_tag="IV356_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP9014663.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            44778..>45201
                     /locus_tag="IV356_000958"
     CDS             44778..>45201
                     /locus_tag="IV356_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HAP9014664.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQI"
BASE COUNT        14016 a         8159 c         8596 g        14430 t
ORIGIN      
        1 gaagagaata atctcttctc ttttttctat tatatataga ttttctctat tttttggtaa
       61 gggagctgtt tcaaaaatgg taaagagcgg aaatgttgcg aatatcagtt atttaatgat
      121 atgatattcg gaaaaagaaa tctcaaaggg aggtaacttt tatgggattg aatgaattta
      181 ttttaggatt gaacaattta gagacgatca caagggcacc tggatttttt aaatatacag
      241 agcatacagt tgcagcacat tcgtatcgtg tagcatctat tgcgcaagtt ctaggagaca
      301 ttgaagaagc gaatggacaa ccgatcgatt ggaaactgct ctatgaaaaa tcattgaatc
      361 atgactacac agagcgtttt attggtgata tcaaaacgcc ggtgaaatac gcaagcaaag
      421 agttaagagg gatgctgcaa acagttgaag aaaagatgac ggacgaattc atcaaccaag
      481 agattccagc tgagttccaa gaagtttatc gccgtcggtt gttcgaagga aaagatgaaa
      541 ccgtagaagg agaactatta gccatttcag ataaggttga ccttctttat gaatcttttg
      601 atgaaatcat caaaaataac ccggaaaaag tttataagga gatgtttatt gaggcagtga
      661 ctacgattaa aagctttgaa catcggcctt ctgttcagta tttctttaaa gagatatttc
      721 cggaactatt gaaccaggaa ttttatggaa aagaggcgtt tttagaaacc gtctcaacga
      781 ttgtaaagaa agaagaaaaa taaaaatgat atgagatgca gggggaagta tagttgaaaa
      841 agaatatgga tgtcgaatgg ggctattctg gagacaaagg tccggaaaat tgggcgagtt
      901 tatgtgattg gtttgcgaga ggtgcggaat ttccattgca gtcgcctatt catttgacca
      961 agggggaaga aaccaaaata gaaggagaca cgctttcctt tcattatcaa aagcaacggt
     1021 ttactgacaa ggaattcaaa aacacgattc atttagtacc ttttgaccaa ctcagttatg
     1081 tagagttcaa gaaagaacgc tattatttga cagatattca tttccacttg ccttctgaac
     1141 atatcatcaa cggaaaacag gaagatattg aatttcattt tgttcatatg aacagcaaaa
     1201 aagagaatct agtcgtgggt gtcatgtacc agctaatgga acaggaaggt tggctgtata
     1261 atcaagaaaa tggggaaagt tggaacttag aaaaacatga gcattgggta aatccggatg
     1321 tgttctttcc ggagcaaaaa agccatttcc attatattgg ctcattgaca actccgccta
     1381 ccagcgggcc aatccaatgg tttgtaatgg atcatgtagg aaaactgaac caagattttc
     1441 ttctcccctt cgatggtcag tatgctcgac cgaacaaccg accaatccag cccttgaatg
     1501 gaagagaaat ttattatttc gaggagtttg agcaatgaat atccagcaga tgaaatacgt
     1561 ggtcgctgta gcaaacaatg gtagtttcag agaagcggca aagaaaatgt ttgtctccca
     1621 gccaagtctt tcagctggta tcaaagaatt agaaaccgag ttagggatca cgctgtttac
     1681 tcgaacgaat cgaggggcat atttaacaga agaagggcaa gacttcttaa atcgtgccga
     1741 gaaaatattg gtccagcttg atacattaga aactcactat ctaacgagtg aaaagagaga
     1801 caatttttcg atcgctgccc agcattatga tttcttaggt cctttgaccg cacagctact
     1861 cgaggaattc aaagacgaga tcaaacaatt tcggatcatg gagacgacaa cagcgagagt
     1921 gatcgaagaa gtcaaagagc agcacagtga gatcggcatt atttatatga atgagcataa
     1981 tcaagctggt atcagaagat atttacaact aggagagcta agtggccgca gcattggaaa
     2041 attcaaaacg catatttttt taaggcaagg acatccatta gctgaacacg cagagatcac
     2101 caaagaagaa ttgttatctt atcctcaagt tcgttttaca caggatggaa ataatttccc
     2161 gtatttttat gaagacctta tcgagatcct tgatcaagaa acagtgattt atacgagtga
     2221 tcgaggtact ttgatgaata tcgttcttga aactgatgct tacgcttcag gatctggtat
     2281 tgtgattgga gggattcgcg agcatttgcg gttaatccct ttggcagaag gcgaactaaa
     2341 tgaattttat atcatttatt cggcgaaacg tccgctcagt gaaatcgctc aaagatttat
     2401 caaagagctt actcggttac tggaccagca gagctaagaa aagcagatga gaacgctgtt
     2461 tattgaacac cgttaatcaa aaaagagggg ttgtgacaga attttgtcac aactcctctt
     2521 tttgtagcaa acaatttata actaattgct gttgtgggaa agtacgcaaa tatgattcta
     2581 gaaacactca ttgattacct gttttgtttc atagctgtaa ttttttcttc ttctggtgtc
     2641 acgataatcg tcttttggtt ttcataaata acataaccag gcttggcgcc atttggtttt
     2701 cggatatgct ttacctgtac aagatcaacc ggcacttggg cagagtatcg gtattttgaa
     2761 aaataggcag ctaactcggc agcttctgta attgtttcat cggagggctt gtcactttta
     2821 atgatgacgt gcgaaccggg tatatttttt gcatgaagcc aatattcggt ttttttagct
     2881 gtcttcattg tcagctggtc attttgaaga ttgtttttac caacaagaat gagcgttccg
     2941 tcagaagaaa agtattgatc aggctgagat ggtttcttac gtttttgttt ttttaagttc
     3001 ttctttttca ggtatccttc tgaagtcaat tcttctttga ttgcttcgat atccattggg
     3061 ccggcaattt ccagttgaga taagacagat tcaagatatt ggatttcatc tttggcttct
     3121 tggatttgtt cgccaatcag cttaacagcg ttcttcagct tttggtaacg atggaaatat
     3181 ttctgtgcat tttgatttgg tgtcaatgcc ggatctagtg ctattttgat tggccgatct
     3241 tcttcataat aattaggtaa aacaacttct tttgcgccgc gtggtacttg tgtcagaaaa
     3301 gtagtaagta gttcgccatc tctacggtaa ttctcagcgt tttcggattc tttgagtgtt
     3361 tgttcacgtt ttttcaattt atttttattt cgttttagtt cattttcgat ttttcgaatc
     3421 agttctccgc cttgttgttt tgcccgatct ttctctgctt tttcgtgata atagctatct
     3481 aataattgac tgagtgttgg ataagctgtt acagcagatg cctgttcgga caatacctga
     3541 taagcaatcg gtgtgaaaaa atttttattt tccgtttcgt aaaaagtagg aataggctga
     3601 tggctgatgg ctgagaaaaa ttcgtcccat acaaccatct tttcattagg acgttccagt
     3661 aatcttttgg tcagctcttg agcggtatcg aaaccgattc cctgaaactg acgttggatt
     3721 gcttttggct ctagttcagt ttgggaaagc cgatgaaaga ttttttcttt ctcggagcta
     3781 aatgggttca agacctcttg ttttggcgga gcaacatatt ctacaccagg aagcaaagaa
     3841 cgataagtgt tttgagagct tccaatgtgt ttgatcgcat ccagtatttt tccagtttct
     3901 cgattaacta agacgatcgt actatgacgt cccattaatt cagcgatcaa tatgatattt
     3961 tgtagatcac ccaactcgtt tcgtttagca aagtggaaat ggatcactcg atcattttcg
     4021 atttgttcga tgtcttctaa aatagcgcca tccaaatatt ttcgaagcat catcacgaag
     4081 ttaggcggat tatcaggatt ctgataatcg atttgggtaa tctgtacacg agcataactt
     4141 gggtgcgcag ataataataa tcgatggttt ttgccgcgtg aacgaatcac cagcacgatt
     4201 tcattttcat aaggctgatg gattttcgag atccggccag atagtaacgt ttcacgcaat
     4261 tcgttgacca tcgcgtgggt aaatacacca tcaaaggaca tggttcattc ctcatttctt
     4321 ttcataagta tattcattat aacgaaaaaa agaagaaaaa ccaatttggc cgaatagtaa
     4381 agtaaaagtc tagaaaaatc ttggactaat tacataaaaa acagtgtttc tatcgttgaa
     4441 atccaaattt ttaggtataa taaaaaatag gagaaaaagt agaaaagaag gtgtttgtta
     4501 tttgggaagt agttaaatcg agagtacaag aaatgaatga acatttctca gtgtcattcg
     4561 cagaaaatcc aagtaagtat tttcgacgtc ttgtgtttct gctcatctta tcattgctgt
     4621 taacagttgc aatgttttta ttgccggaaa aaatccgaga agagcaagta aatagtctcg
     4681 tttattcgtc cataccaacc agcaaattga aaccttttga ttacagcaaa gctgatcaga
     4741 aaatcagaca aagccgggcg atatcggtga tgttcagcaa accgaacggg aaaacctatc
     4801 aggacatgct tgatgttttt aatgatcctg agcttatgga agaattgaat cgaccgatct
     4861 tttattatcc gatcgtttat gatgtacatg aactggaaca aaaatataac atacgaacgg
     4921 atgaagtgac atttattttt tttgatggag gaaaagaagc aaatcggata actgcgggta
     4981 agggaggaat aactgatttt gataaggagt tgatccctga actgaatcga cttccgttag
     5041 ccaatatcaa acaattagaa gaagaattgg atagaacggg agtaacttcc caaaattccg
     5101 agattgctaa ttgagacatt ggcgcgatga aacggtgggt ctatatagcg ctatttttaa
     5161 ttatcagaac aagtgatgtt tgatcttcaa aataacaaat aaaaaattaa aaaatatagt
     5221 tgacgaaatt caaaaattcg attagactta aatcaattct taaggaaagg gtgacctgta
     5281 atgaacttat caaaacgtat ttcagcagaa aacaaaaaaa attggcgcag ctggcgtaga
     5341 taagttgtat taatggtgag actttcccat agatacaact ttttagagtg catttctaaa
     5401 gcttgtatct atgctagaca tgaacattga ctgccgcata gattagaatc tatgcggttt
     5461 tttgtgtaaa gacaatgacc gctttggcca ttgtcttttt ttgtagactg gatacttgcc
     5521 taattataat aaataaaaag attgactttg caggaggaaa aaaatgaaaa acaaacgatt
     5581 aataacagtt gtagtaatta ttttagttta tttagcaggc gcatttattt atggaaaagc
     5641 ctcaggcgaa aaagaaagta cttcgacgaa ccagacaaaa aaaacaacag ttgttggggt
     5701 attgcaatac gtgagccatc cggcattaga tgagatttat cgaggaatca aagatggtct
     5761 gaaagaagaa ggattaaaag aaggagaaaa tcttgagatc aaatttcaaa atggacaagc
     5821 cgatcagagc aagctagcca caatgagtca acagctagta caatctgatc cagatgtctt
     5881 gattggaatc gcaacacctg ccgctcaatc attagcaaac acgacttcat cgatcccagt
     5941 tgtgttaggt gctgtaacgg atcctgtggg ggctggatta gttgcttctt tagagaaacc
     6001 tggtggtaat gtaacaggtg tttctgatca gccgcctgtt gcttcacaaa tcaagcttgc
     6061 ttctgatttg ttgccaaatg caaaaaaagt cggaatcttg tatgcttctt cagaggataa
     6121 ttcaaaatac caagtagcac aagcagaaga agctgcaaaa aaagaagggt tagaatcagt
     6181 aaaatatgcg gtgccttcca ctaatgagat tgcacaaacg gttcaagtga tgagccgaca
     6241 agtcgatttt atctatgttc cattagataa taccattgcc aatgcgatgc aaacagtggt
     6301 aaaagaagca aacaaagcaa atatccccgt cattccatct gtggatacaa tggtggaaca
     6361 aggtggacta gcaacaatcg ggatcaatca atatcaatta gggcttcaaa gcggtaagat
     6421 ggcagcagaa cttgcgagtg gaaaagaaaa accggaaacg acgcctgttt atacatttga
     6481 tcaaggggat acagtgatca atcaatctca agctgatcgc ttaggaatca ttgttcccca
     6541 atcgatgaag gaaaaagcca aaatcattac agatgactcg cagcaagaaa catctaagga
     6601 ggatgacaaa tgatcgtatc agctatttca caaggcatgc tttgggcaat attaggatta
     6661 gggattttca tgacttatcg gatcttagac tttcctgata tgacgacaga agggtccttc
     6721 ccattaggtg ctgctgtctg tgtgacagct attactcatg gggtagcgcc gattgtagct
     6781 acattattag gagtaggtgc tggcatgata gcaggactcg ttacggggtt actttataca
     6841 aaaggaaaga taccggttat tttagcaggg attttagtga tgtcaggatt gaactcagtt
     6901 attttgtttg tgatgcgaac accaaatctt tctttattga atcatccgat tctacaagac
     6961 agcttccatc gctttgggtt acctgattac tttgacacag tccttcttgg cttcatctct
     7021 ttgggcatct tgattgctgt actgctattc ttcttcaata cagatttggg tcaaggctat
     7081 attgcgacag gagacaacga aacgatggct cggtcgttag ggataaaaac cgatcgtatg
     7141 aaaattttag gtttaacttt gtcgaacggt gtcattgcat tatccggtgc gctgattgcc
     7201 cagaacgacg gatatgcaga tgtaaataaa gggattggcg taatcgtcat cggtcttgct
     7261 tccatcatca tcggtgaagt gatcttccaa gaattgacgc tagcagaaag attgattgct
     7321 attgttgtcg gcagtatcat ttatcagcta ttgattttag tagtaatcaa actagggttt
     7381 gacacgactt atctgaagtt gttctccgct atcatcttag ctatttgtct gatgatcccg
     7441 caattgaaga aagcactgaa cttaaaaacg ggttttgaga aggaggcata gtaatgactg
     7501 atatattgac aatcaaaaat ggcagaaaag tcgtaaacaa tggaatgaat gaagagaaag
     7561 tactattgga tgaaattaac cttacaatca gagaagggga cttcatcact gtccttggcg
     7621 ggaatggtgc tggaaaaagc acactgttca atacgatcgc tggtacgctt caactcagtc
     7681 aaggatcgat ctcttttaaa gatcagctga tcacaaaaga ttcagaagaa aaaagagcac
     7741 gattcctttc tcgagttttc caagacccca agatgggaac ggctcctcgg atgacagtag
     7801 cagaaaattt gctacttgca caaaaaagag gtcaaaaacg gaaattccgt ttacgtaact
     7861 tgaaaaatca aaaagaagat tttttcagac tatgtaaaga agtcggtaat ggcctagagc
     7921 aacacttgga tactccagcg ggtgaattat ctggtggtca acgccaagca ttaagcttgc
     7981 tgatggcgac gatcacagct cctgagttac tattattaga tgaacatact gcagctttag
     8041 atcctaaaac agctaaagca ttaatgcgat taacaaatca gcggatcaat gaacaaaaat
     8101 tgacttgtct catgatcacg catcgaatgg aagacgcctt gaaatacgga aatcgtctga
     8161 tcgtactcca aaaagggaaa atcgttcaag atatttctga aaaagaaaag caacatttga
     8221 caatgggcga ccttttgcag ttctttgaag aagtagtgga ttgatttcga cagaaaaatt
     8281 cctttcagta gaaggacttg aaaactcatt gacatcttcc tttgattcat cctatactta
     8341 aaacaataaa caattaaaca tatttgggtg ttttgtagga tcacgtagtc aatgatttta
     8401 acaattaaat agaatattct ttgctctgac aagtaaacga tgagaaaaga atttgctact
     8461 ttgccaccta gacgtttcgt actttttcgt atcaaacgct aagtggcttt ttttattgaa
     8521 gtaagaacaa aggaggaata agatgatttc tggacaaacc aaattagctg ggctctttgc
     8581 tgatccggct tctcacagtt tatccccatt gatgcacaat actgcttttg aagcaaacaa
     8641 catcgatgcg gtgtatttag ctttccaagt aaatccaatg aatttgaagc aagcagtcga
     8701 aagtattcga acttttgata tgttaggtgt aaatctttcg atgccgaata aaacagcggt
     8761 tattccttat ctggatgagg taagccagga agcgcaattg atcggagcag tgaatacgat
     8821 cgtgcacgaa aagggtcgtt tgattggcta taataccgat ggtgcgggct tcatgcaatc
     8881 cgtgcaagaa gctgggattt cgatcaaaaa gaaaaaaatg actctactgg gagctggagg
     8941 tgcagcaaag gcagtcactg ttcaagctgc gttagacggc gctgaggaaa tcgtagttta
     9001 taaacgaaac aaccaaacat tcgctcaagt aaaagaaaca ttcgaacaac tcagctatcg
     9061 aacttcttgt aagataaaag ttcgtgactt tgccgatacg catcaattaa gaaaagactt
     9121 gaaagaaagc tgtcttctag tcaatgcaac agatatcggg atgggaaaga aaatcaatca
     9181 gtcaccgctc ttagatataa gcatgatgca tgagaatcta gcggtttttg atttgattta
     9241 tgcacctaga gaaacacgtt tattaaaaga agcaaaaaaa gtaggagcaa aaggatacaa
     9301 tggacttggc atgttgatct accaaggagc aatcgcgttt gaattatgga caaaggaaaa
     9361 gatgccgatc catgtgattg aaaagctgtt tgattaaaaa aggataatag ataaagatct
     9421 tttattctcg cataaacggt ctcaagaaaa gtaatccttt atgtatcgaa gcatttattt
     9481 cgttattttt tattaaatta tcaaaaaatg ataggctttt gtcgattggt tatcgtatcc
     9541 tttatttatc agtaagaaac gaggaggaac cacaatgagt cggatggatc gctataagga
     9601 catccataag aaggcgaaac ctctgaagcg ggatacgggg agtatttttg ctagaagaga
     9661 acgaaaacga acgcgtatgg aaaatgagga agatgctacc cgtatttatg aaagagagca
     9721 gcattcattt gaacatttga accaatacga gcaacagata tacagagatg caccaagagc
     9781 agaagaacaa caaaaaaata aaaaattttt caatcggcaa aagaagaaca aaccgttaaa
     9841 acctcgaaga aagcgatcgt ggaaaaaaat cattctatcg attttgcttg ttttgatcct
     9901 ttattcaggt atctcatttt ttattggtaa atatgtagct gaacatgaca caagcttaga
     9961 ggcagcgact tcagaaacct ttcatgggca aaaagcgacg aatggtgcgc ataatatttt
    10021 gatccttgga agtgatacac gcggagaaga tgccgggcga gccgatacga tcatggtctt
    10081 acagttggat ggtccttccc ataagccgaa actgatttct tttatgcgtg acagcttcgt
    10141 tacgatccca ggggtaggac aaaataagat caattcagct tatgcatacg gaggagccga
    10201 tctagtgcgt caaactttag tagaaaattt tggaatcgat tgtcaatact atgcgaaagt
    10261 cgatttcaaa tcgtttgaaa aagtgatcga tgccttattc atgaacggag tgaagatcga
    10321 tgcagaaaaa gatctgaatc tggatggtgt agatattaaa aaaggggtcc agaagatgga
    10381 tggacatgtt cttttgcagt acgcacgttt ccgaatggat gaacaaggag actttggccg
    10441 tgtcagacgc caacagcaag taatgaacgc tattttcagc caattgaaga atccattgaa
    10501 tctgatccgt gcaccttatg cagctggtgg cattgatcga ataagtgtgc cagtagacgg
    10561 ttcgtggaat tatgggcaaa gtgattatgc tggcagtatt cttgaaattg ataatcaaat
    10621 gaatcaatct gctattacag attttttgaa taaatgatca taaaaaagat caagaagaag
    10681 ctgcgcaagg cttttgtcat gaatcaatca aacgattcac tcgtaaaaaa cgctttctta
    10741 tggtagattt aaccaagaga ggagctgttt acattggata tctatctgaa cttcaaaaat
    10801 gagtcgcgtg aagccatcgc tttttatgaa aaagtttttc agactgaagc atcaggtatc
    10861 accacatacg gtgaaatgcc tggaatagaa caaatgaact tgccagaaga agcaaaaaat
    10921 ctaatcacga atgcacggct gaacatttat gatacattag ttatgtttgc agatacgcca
    10981 gaaggaattg gtcctgaatt agttgtggga aataatgttt ctttagtcat ccagacaaga
    11041 aatgaagaag aaacgaagcg cctatttgaa agcttagctg agggtggtaa gattgagatg
    11101 ccactggatg ctgttccgtg ggctcagttg tatgggatgg taactgatcg atttggcatc
    11161 aactggcaga ttaaccaaga gtgacagcta aagatgaata ttttctggaa acatcaagca
    11221 gcaaacggat catcgtttgt ttgcttgatg tttttgtgtc tatttcgact atacggtatc
    11281 ttttttttat tgccagatgc gaaaatatgt tccataatag agaagtccgc aaaaaattaa
    11341 gtaacggagg tcagaagatg aagacggtga tactagctga aaaaccttca caagcaaaag
    11401 cctatgccga aaccttccaa cagcaaaagc ggcatgaagg gtattatgaa atcagcgatc
    11461 cattgtttgc tggtgaagta accatcactt atggttttgg acatttggta gatatggttg
    11521 ctccaggagc ttatgaagag cgttgggcaa aatggtcttt agaaaatttg cctattttcc
    11581 cagaaacctt ccgttacgaa gttccaatgg acaaacgtgc acaattttcg atcgtaaaac
    11641 gagaattgca gtcagccgat accatcatta ttgcaacaga tggtgatcga gaaggtgaag
    11701 ccatcgcgtg gtcgattatt cgacaagcaa acgcattttc taaggaaaag aactatttac
    11761 gtttatggat caattctctt gaaaaagaag caatctatga aggttttaag aatctccaac
    11821 ctggaaagaa ctattttcca aaatataaag aagcgcaagc aaggcagaac gctgattggc
    11881 tgattggaat gaatggaagt ccattatata gcttgctact tcaacgaaaa gggattgatg
    11941 gcagtttttc tcttggtcgt gtacaaacac cgacactcta tatgatttat cagctgcaag
    12001 aagaaatcaa acacttcaaa aaagaaacgt actttgaagg agaaggttta attacgacaa
    12061 acaaagggca gttttctgga aaaatcgtac caaaaaaagc atttaaaacc caagaagagt
    12121 taacgaagga aatagaaaaa cttggagcgc atttaggtaa gcaaaacgga cggattcttg
    12181 aagttacgaa aaaggaaaag aggttgcata gtccacgttt attttcgcta tctagtttgc
    12241 agacaaagat gaatcagcta atgaaagcaa gtgccaaagc tacacttgat gctgctcaag
    12301 gattgtacga aagcaagttt ctaagctatc caagaacgga ttccttttac attacagaaa
    12361 atgagcatca gtatctggtt aaacatctgc aaaattataa aaaattttta ggaatagaag
    12421 aagtacagac aactgagatc aaagcaaaga aacgatatgt cgatgcgaaa aaagttcaag
    12481 aacatcatgc aattattccg acaaagacga ttccgactcc tgcacgcttt gcgaagcttt
    12541 ccaaattaca gcaagcaatc tatttgcaag ttttgcgcac tactgtggct atgtttgctg
    12601 cagattatat ctacgaagag acgaccgtaa tgacgggcgt acagcaatta aagctaaaaa
    12661 gcatcggaaa gatcccatta cagcaaggtt ggcaggaaat cttacgcatc aagtcaaaaa
    12721 agaaagaagc tcagactctt cctcctatcg tagaaaatga agaagcagaa gtagaactga
    12781 aaagtatgga gaaagaaaca caacctccaa aaccctatac cgaaggaacg ttgatcacag
    12841 caatgaaaac tgcgggaaaa acgctggata atgatgaagc gcaagaaatt ctcaaagaag
    12901 tagaaggaat agggacagaa gctacacgag ccaatatcat tgaaaatctt aagcagaagc
    12961 attacatcga agtcaataaa aacgaaataa ctgttacgcc aaaaggaatc actctttgta
    13021 aggcagtagc caatgaacca ttactgacga gcgcagaaat gactgcgcgc tgggaagggt
    13081 acttgagaaa aattggtaaa caagagggga caccatctgt ttttttagag aatatcaaaa
    13141 aattcatcct acatttattg gcagaagttc ctaatcaaat cgacaaggta gacttttcag
    13201 atgagattag cgggacacgt cagataaaag cgatggagaa gaaaaacgat caattaggaa
    13261 gatgtccaaa atgtaaaaag ggaatagtca tgctttatcc taaaatcgct acatgcttga
    13321 atccggaatg cgacttcaaa ttgtggccaa cagtagctaa aaagaagctg actaaaacga
    13381 atctcagaga tttgctttca aaaggaaaga caagtaaagt tgtcaaaggt tttactggta
    13441 aaaaagggaa attcgatgca gttttagtat taaaagaaga tatgacaatc ggtttttctt
    13501 ttccatggat cgaaaacagt ggaacaaaag cagttgatgg aaacaaagaa acatcaagaa
    13561 aaaataatga aaacgaagta gagtaaatga aaacaatgaa atagcggaat atttattccg
    13621 aaaagtgaga atataaatac caataaaact aaaaaatatc agtgaatcaa gcaaaaacgt
    13681 tggggtaggc tgattttata tagatagcaa ggagtttttt tatttgaaaa aagtgcattc
    13741 atttttaaat tatcttatgg gagcaatcac gattgtggct gtgtaccaag catttctaaa
    13801 gtatcctgat tacgggacga agttgttgtc attgacgcac aatcaaacag catattcacc
    13861 aacgttgatt ttatcgactt tgactgcagg agctaaaagc gctacttatt tttttcataa
    13921 aacgacaagc atgctaaagc gaaagaaaca gcgaaaacaa ttgttggtgg tggtagcggc
    13981 tatgatcatt atttattttc taccagttat tacacaagta tttcatcaat attttggtta
    14041 agaatacgag agtttgtgac aaaagtcatg tcacaaactt ttttctttgt cattttttcg
    14101 taagaaaaag caaaataaaa gtatatacat tgattaaaag tatatacttg gatataatgt
    14161 acttactata gaatgagaat ggtatagagg gtggcgaaat atgaaaaaaa tgaaaaagta
    14221 taaaattaga aaatctggca atagcgatgt aacaactatc ccaccagaag taaaagaatt
    14281 catgggtgtg cagacaggtg acgcaatcag ttatgttttt caatctgatg gttctgtacg
    14341 aatgatcaaa gcacaagaag aacctgatat tgattcatta gttgattcga tcatgaatca
    14401 atatgaagac gcgttaaaag atttggttga tttatgaggt atctttcgac taaagaaatt
    14461 atcaaaatca acgcgaaagt tattttacgt cactcgccag gcgaaatgat cggtgtaaaa
    14521 gatgcaaatg cattagatat ggccgtcaaa cagccttcac aagcagtatt caatcaagaa
    14581 ctctatcctg aaatctatga aaaagcggcg attttagcaa ttaatttagc taaaaaacat
    14641 ccttttcata atggcaataa acgaactgct cttgttgcca tgttgttgtt tcttcaattg
    14701 aataattgtc cagttgcttt ttctcgtcaa gaagctgttg attttatcat aatgattacc
    14761 actagttcat tggatttcga ttcactaaag tccaagataa ccagttattt acgacaaacc
    14821 gcaataaaat gaacgaatta aaaactttat ttctcaatta gatcagcatg tcattaagga
    14881 atatgctgat ttttttatgt ttaatcatac aaaatagttt tttcataaaa atatggaaaa
    14941 tatggattaa ttttgaaata attgatttaa aaggaataca aaagagtgaa tagtaggaaa
    15001 tagtggttta gaactagtgg gctgattttt tatatatttt agtttacata atatatatta
    15061 tacaaagtag atttaaaaaa tgataaacct ctctcgaacg gttttttatc aaaaatcgtc
    15121 atttttccat caaaatctgc ttatgcaaaa ttataaaaaa attttgcagt ttttcttact
    15181 ttttttgtcg tttaattgaa tgataaaaac cagtttcttt attcagttaa tcaaatatga
    15241 acgaattaga tatgaatcat tgtatttgcc gttgcggaag gattttttaa ttaaccacag
    15301 ataaacattg ataacgattc gcttattgta atcaacagat taaatttcat atgttcatat
    15361 gtacggatac attttcggac cgattaattt taaccattct gtttatttgc ttacctatta
    15421 gatatcaata aaaaactgct taacagctat ttcagctgtt aagcagtttt aggattttta
    15481 gttcatattc attgtttctt ataatacagt gttcaatact tctcttaaag cacttgttga
    15541 tttgctgaac attgcttttt cttcttcgtt gattgataat tcaacaactt cacgaacacc
    15601 attttcgtca acgattgatg gcacacctgt aaagatatct ttttcgtcgt attcaccagt
    15661 taaataagca gatacaggca atacagcttg ttcgttattc aagatagctt ttacgatacg
    15721 tgcagtactc ataccaatac catagtaagt tgctttttta cgatcaatga tctcataagc
    15781 agcattacgg actttatcag caatcacatc taattcatct tgggcaatac gatggtcttt
    15841 ttctacaatt tcaaacactg gtttaccacc gacagttgta tgtgaccatg cagcaacttc
    15901 tgaatcacca tgttcaccta agatatagcc gtggacgctg cgtgggtcaa cttttaattt
    15961 caatgcgatt tctttacgga aacgagttgt atccaatgtt gttccagtac cgataacacg
    16021 tgatgttggc agaccagatt cgttccaagc gatatatgtc aaaatatcta ctgggtttga
    16081 agcaacaacg ataataccgt cgaatcctga tcccatgatt tcttttacga tttggcgcat
    16141 gattgacgca tttgttttaa ctaaatctaa acgagattga ccaggttttt ggttgatacc
    16201 agctgtgata acaacgatat cagcatcttt acattcttca tagccacctg accatacagc
    16261 cacattttca tcgccccaag ccataccatc taaaaggtcc aatgcttccc cttctgcttt
    16321 ttcttgattc acatcgatca atactaattc attagagatt ccttggttga tcattgcata
    16381 agcgatactt gttccaacaa aacctgtacc gacgattact actttacgac ttgttttttt
    16441 catgaataaa cagctccttt tcataactat ttgttacttt catgaaaagt atagtcttgt
    16501 ttattcattt tatcaacatg ttaattataa tagttgttat tataattttt gatggaaacg
    16561 aattcctgaa tacgcataac agataaatga caaatgttta cacctatatc ccctgataat
    16621 acaaccaaaa gtttagaact gaaaataaat ccaaaaaaat tcgctgcaac gatataataa
    16681 gacagcaatc gcacctaaaa caattttcct tcatatgctt tagtgaaaga ttttcttctt
    16741 aatgtttatt tctccattca ttgggagtac atgttgaata cttcttgaat aatttgaata
    16801 aagaagtcgt ttgtttatat ccgatacgat tagcgatttc ttccaacgaa aaactcgttt
    16861 cttgaatcag ttccaacgca aagtcgaatt ttttctttag aaccagttct tgaaaggaag
    16921 catcaaaata cattttcaat ttattactaa gatagaccgg attgtagcca aaatgagctg
    16981 ctgtttcttt taacgtacaa gaagtaaaat gcttatcgat ataatctaat actctaagca
    17041 tctcattttc tgcgcatcca tctgctgatg aaaagctttg ttgttctaat aaatgagtca
    17101 attcgatcag taatagtgat gtatagagat ttaacgaacg gatcttatga ctgtatgtat
    17161 caaaataaat caacagcata ttttcaatca aatgcgtcaa acgacttgtt tttccgccgc
    17221 gaaaatgaat gaattgtgta tgttcccctt tttcttttga tgcatttatc aaaaaagaag
    17281 aaagtagatt atttgtgctt gccaaatgat tcaatatctc tgtagataag gtttcttctt
    17341 ttaataagat gttgattaaa atatcctctt gccctgtgta ttcgattctt tgagtagctt
    17401 ctttatcaat gatcaccacg tcactttctt ccatctctat cctttctcca ttaataattt
    17461 gtaaacatgt accgctatac atataattga tttcaacaaa atcatgtgta tgctcgggaa
    17521 cttccgcata tcgacggtgt ttactgatat gaatatttcc ctgttgaaat agatcccctc
    17581 ggtggatttt tggcggtgtc tgaagatggt aagctaagtt taaatcattg atattcattc
    17641 cttgttcacg ctgcagagtt tcgattgatt cttcgttacg caaaaaaaat gtctaattca
    17701 gctagttcca attgactccc tcctttttgt aagcggtttc tttcgcttat tagttcacgc
    17761 tgtactgcta ttatatgcaa agctattttt ggtttcataa agactttcta tggttgggac
    17821 atgaacttcc tgtgattccg ctattgagag aataaccact tcatactata tttttgataa
    17881 gcgcttacaa aaatgaaagg aacatgctta tgaataaaaa gatgatgaaa ttttctctgc
    17941 tgtcagtctc tcttattttg acttctgctg gtgcagtcac gtctgcaatt cccagtatgt
    18001 cagctactta tgccacgcgt tctttatctg ctgttgaatt attaacgact gctccctctt
    18061 ttatggtcac tatttttgtt ttgattagta gttttattgc taggaaaatc ggacaaaaac
    18121 aaactgtgat catcggatta gtgattgcat cgatttgtgg tatcctcccc ctcttctcac
    18181 aaagttacag tattgtctta gcttcaagag ctggactagg tattggcttt ggattgatca
    18241 attctttggc agtcagcatg attgctgcct tttatcacgg agatgaacga gcctctatga
    18301 ttggttttca aagtgcattt caaggatttg gtgcagcttt aatgacattt gttgcaggac
    18361 agctagtaca gttcggttgg caatatacct ttttagtcta cgccatcagc ttacctattc
    18421 ttgtcttgtt tgttttgttt gttcctacac ctgaaacaac tgaacttcaa tcgcatggca
    18481 cagccccaac aagacaagta atcaaaacga atcctaaaat gattagttat ggtatttttc
    18541 tcttgctggt catcgtggta tataatgctg tatcgattaa attagccaca gtcctgacga
    18601 cttattctct aggaaacgaa actaatgcag cgaatatctt aacaatcatg caattggcaa
    18661 gtatggctgc cggagtttgt tttggctggc ttcagacaaa agcacatcgc tatatgctta
    18721 cactttcttt actactgatg ggaatcggct ttgtattgat tgccactgtg ataaacctgt
    18781 atgtgattgg gtttggtgcg atcctaacag gaatttcttt ttcgttattc attccttact
    18841 tattcaacca agtaagtatc caagcgccca agtacgcgga gagtttcaat acttcaatct
    18901 tattggttgg cgctaattta ggtactttca ttgcaccata tggtttgctc tttctctctt
    18961 ttgcttctct tgggagtaaa acacttgctg ttttcgtcaa tggcagtatc ttgctgttga
    19021 ttagcgcgct tattagcctt ctagtagtac acaggacgaa tagaaagaca gtgataagag
    19081 tagatgaaga aataaaagaa caattgacaa caaaataaat ttgatggagg tcgtgtaaaa
    19141 tgacaaatga aaaacataaa gatagatggc tttggtatcc tggagacttt gagatccgcc
    19201 atggactgct acaaaatttc caacgggaag aacgaggttt tgactggcca gcgtactggt
    19261 acatggatga ttgccatcgg aacgtcaagt ttaagagata ttactttctt gatcaacctt
    19321 ccatgtttaa agtgacgatc caaggagttg ggtatgtaga aattaatgga caaaaacatc
    19381 catgtggaaa atggctgact tgtccagctg gtaaagcaaa aattcgtatc tttgtaggac
    19441 atacatcagg gctaccagcg atgtttatcg agggagacga agtaaaatca gatattggct
    19501 ggacagcaag taattttatt gaagaatatc cagctggctg gagtccgctt tatgtcgata
    19561 tcgcaaaaga tccaaatcaa atctattatc aaaaagaatg cgtccatcca gtcactgaaa
    19621 cggagattgg cggaggaatc ttattcgatt ttgggcgagc agtgaatggc tgtgtagaac
    19681 taatatctct ggatgaccat atcgaatcta tcactctatg ttatggagag tccgatgtag
    19741 aagctatgga tatcgattat tgctactata agcaaatagg aatgacaaga aaaatgaaag
    19801 ctcgtaaacg cgcttttcgc tatttgttta taccagaggt ttctactgga atggttcaac
    19861 ttcaagtttt tcatgaattt ttatctcttt cgaaacaagc tgctttttca agcgattctt
    19921 ctttactgaa tcagatctgg tcagtatcag aagaagcctt caagttatgt agtgatttgt
    19981 tttttatcga cggtatcaaa cgagatcgct ggatttggtc tggagatgcg tatcaatcat
    20041 tcatgatcaa tcaatatctt ttttttgacg aggaaatcaa taaacgaacg atattagcat
    20101 taagaggaca aaatgaaatc aagcagcata tgaatactat cgttgactat tcgatcttgt
    20161 ggttgattgg tatcgaaaac cactatatga tgacgaaaga ctatgaattt ttacgcatcg
    20221 tctaccctaa gatgcaatca ttaatgagat acttgatgga gcaaacgaat gaattagggt
    20281 ttatttatgg gagagcaaaa gattggatat ttattgattg gtctgaaatg gataaagaag
    20341 gaacgcttgc tgcagaacaa gtcttattac tgaaagccta tcattccatg atcacttgcg
    20401 gagatatctt agctgaaaca tatggagaga acgaaaatta tcatactcat ctctatcaag
    20461 aaaaatatca actattgaaa caaaacctat ttgactactt ttgggatgaa gaacttggcg
    20521 cttttatcga ttgctatgaa tctgggagaa gaaatgtgac gcgtcatgcg aatattttcg
    20581 ctgttttatt cgattttgct aacaaagacc aacagcaatc gatcttaaag aatgtcttat
    20641 tgaatgacac tatcacacag attactactc catatttcaa attctatgaa caagatgctt
    20701 tatgcaaact cggacagacg aatatcgtct accaaacgat tcttgattat tggggaggga
    20761 tgttatctca tgatgcggta actttctggg aagaatacga ccctactcaa acaggaaatg
    20821 aaaagtacag tatgtatgga gatccttatg gaaaaagctt atgccatgca tggggagcaa
    20881 gcccaatcta tcttttagga cgctatttta tcggtttgta tccaacaaag ccaggttatg
    20941 aagaatttat gatacaacct aatctagatt catttgaaac actgaattgt acgctaccta
    21001 tcaaagatgg aaagatttcg cttgaaaaaa caaaagataa gatcgtgatt acttctgata
    21061 gaacaggcgg aacagtgaaa atgaatggta aaagttatcc tcttctagca aaacagccac
    21121 ttgtcttaac aagctattca aaaataaatg cataaaacaa aaaactgctt gcgacatatc
    21181 agaagacttt aaatcttctt ctgatattgt ccaagcaatt tttattttga agtttgctta
    21241 attctgttct ttagaaacaa tgtttgttct ttttccggca aaaagaaagc tagataatac
    21301 gacaagtaaa aagaaagcga tgattccaac tgtcaaggct atttgaccgt attctcctag
    21361 tttcccaagt acaagtcctg gtactagata atcagtatcg gcaaatgtag aagaagcgat
    21421 tttaagatct cctaatactg gaaggataaa taatggcagc caactaatca ataagctatt
    21481 gaaagcagaa cctaataccg cccctcttct accgccagtc gagttgccga agacaccaga
    21541 agcagctccg cagaagaaat gtcctactac cccaggaatg ataactgtag tttgcaagcc
    21601 tatcatagca aacatggata gtgttcctac aaagaagcta acaaaaaagc caattaatac
    21661 agcattaggt gcatatggaa aaacgatagg aacatctaat gctggtttag aatcgggtac
    21721 gagtttttta gcaatccctt ggaatgctgg aacgatttct gccaacacca ttcgaacccc
    21781 ttgaaggacg ataacaaacc cagctgtgaa tgttccagct tggatcagtg caaagattac
    21841 agcgttgtct ccattgctta gttctctttc aacaaatcca ggaccagcta acaaagcaag
    21901 tgcgacatat acgatcgaca tcaagagcat gatcgataca gtagaatctc gcaaaaagct
    21961 gaaactttta ggaatcttta tgtcctctgt agaacggtct ttgtttccaa aaaactttcc
    22021 gatccatcca ctagaagcat aaccgatatt tccggtatgc cctaacgcaa cttgattgtt
    22081 tccagtgatg ttcttcataa acggttgaca aagagcaggc gtaatagtta atagtgttcc
    22141 ttcgaagacc ccgcctaata agatcatcca caaatttgca gtaaaccccg cgcttactaa
    22201 aatgactgct gttagacaag aaacataaag cattgcttga cctgtaagaa aaatgaattt
    22261 atatcttgtg aatctagcaa gtaaaatatt cacgatcatc cctactagca tgatcaaagc
    22321 agtaggtgta ccgtattgtt gcaaagcaat cgccactact gcttcattgc taggaactac
    22381 tccttgagta tgcagagctg tttggaacat cgaagcaaaa ggggttagtg aattactgat
    22441 taaaccagca ccgccgatca gtactaggaa tccgacaaat gttttgatag ttccttggat
    22501 cacttctgaa aatttcttct tctgaagaac gagaccaagc agtgcaatca aagaaacgag
    22561 gatggagggc tgactgacga ttgacacaaa caaattcaac aatttatcca ttgatagttc
    22621 ctcccttgaa tcatttttat tcttttgaca agatcttcgt tactttttct tttacttctt
    22681 cgctgtcaat gatcgattgc aaaggtacga gcttttcatc aggtatagaa gttagcgtat
    22741 ctttcaaaga atgctcaatg aagaaataat cagccatatc gctagataca cttccaacat
    22801 ccgtatgact tacttcaaac tcgtccacat ctgctccaag atctgcaagt gcttgtttga
    22861 tgttcatctc taccataaaa cttgttccta atccactttg acatactgca aaaattttca
    22921 tatcattcgt ctccttttct tatgatcgct aatatttctt cttttgttga tgcgtgtaat
    22981 aaatcttgaa gattttgttt attagaaagt agctttgtta aatttgccaa agcccgaaga
    23041 tgtgcctcat tatcgatagc agctaaacag atgaacaaac taatgggatg ggctggatta
    23101 tcaagcagat ccacaggttg ttgaagtttc agcaaagaca tccctacttc gtttacgcca
    23161 tcttctggac gagcatgagg taatgcgatg tgatcgccaa tatggataaa cgcaccatac
    23221 tgctccacgc gctcgatcat agctttgata taactttctt ctattttatt ttctgataat
    23281 agcggctgtg cggcaaatgt gattgcttct tgccagtttt ttggttgatc cgataattgg
    23341 atcatttctt ctgttaataa ttcagatagc ataggacgtt gatcctcctt cttttctaaa
    23401 agtttgttca ttttacgatt taatacttga tagagctttt cttcgtctac gccttctttt
    23461 aattcgatat aaggcagtag cgccgacaac aattcttggg cagaaggcat tgaaaatcct
    23521 ggtatcagcc aatctctttg tacttgattg atcagctgat ttttttccaa gtcagtcatg
    23581 attggatgca gaacatagag agactttttc ttatcagtaa gtgtgagagg tacagtagaa
    23641 aaaataatat cgtaagaagt ttcgtcaacc tcgtgtaagc ggtcagctga attagtctct
    23701 gtaaaaaaga tcatcgggaa taattgctga agttcacttt ttaagatcaa tgaagagcta
    23761 atgccacttg gacagacgat cacggctctt atttttctat ttctttcttc tgcgtccgct
    23821 tttctgatct ctccgccaaa tagtatagtg aaaaaaccaa tctcttcttc agggatgctc
    23881 ttccctattc gtctttctaa cggaagtaat gtttttcttg tcatttcgta gatggaagca
    23941 tattgatgct taatttgatc gatcatcaca ttaggtaaat aaaaagaata ggaaatacga
    24001 aaataggcag ggaccaagtg ataaaagaca ttcatcaata attcacgaaa cgaagcaaat
    24061 tctacggcca tcaggaattc catgcgatgg atgacttctg aagaacattc cagcaaaaaa
    24121 tcaagtgcag gctcctggac atctccttca acgatcgatg ctaagcaaag agagaaaaat
    24181 ataatctccg aattttgatg ttcggaatag ccaaggccag tcaatacttg tcgactaatg
    24241 tcagtgactg caagagaagc caacagttca gcatctttta ccagttccat ggatgttttt
    24301 ccaattcgaa tggttgtcaa actcaaataa taagctaatt catccattcg atttggtgcg
    24361 aatcgaagat ctgatagtga aatcgtttta tctagcaaat ctctaacttt ggcgtaataa
    24421 tcaatggaaa gggttgcggt taaatacgtg agcccaaatc ttccagcaag tgactgcatc
    24481 aaacgagcag tgcgattttt tgcttctctt cttaatattg cttctgaccc tagcagccta
    24541 aaaccagttt tcctagtata cgacagctga caatcttcca cttctaattc atttcttatc
    24601 tttttgatat ctgacaggac tgtcccttta gaaacctgaa gaaaatcttg aaaatgaaaa
    24661 acagaaacag acgttgcagt cgaataaacc atcaaataaa gaagatctct tcgctcttgt
    24721 tcggtataca cagcttcaaa tcgagtaata tccaaaaatt tttctgccca gtcgattgct
    24781 cggaatttct ttatacggat acgggtatca tccacatatt cggcaaaagg agttaattgt
    24841 ttgatcgcct cgcttgtatt tacttcgatg atctctgctg ctttttctag actgatttct
    24901 cttggtgttt tcaggagata actaattttg tagttcacag cgctgttcac ctcctactta
    24961 tattctagta tggtagcgct tttaaatcga ggggtgtttg gtacaactta cagttggatt
    25021 ttttttacga ctgtaccgaa cgatttctat cgaatggata cagaaaaaaa gcaggtgacc
    25081 aaatgtctcc tgcttttatg aattgatttc gtccgatcaa tgatgatcat gtttattttt
    25141 tgaggtcagt tcttcaaatt tttctttgac atcttcaacc gctttttcga tatctttttc
    25201 aaagtgattg ggctcattag gctttgtttc ctcttctaca gaatttgaac cagataaagc
    25261 tgtttcttta ttttctgttt caccagagtt tgtgccagct aatgattctt ctttgtcttc
    25321 tgtttcacca gaattagttc ctgctaaagc cacttcttct tctgttttag gggccattga
    25381 acctcttaat cgtttgtgtt tttcaccgtc ataatttgtc atgttggttc ctcctagtag
    25441 ttctatactt tttcatcgta caataagaca gtttatgcgt caaaaaacaa acccgattct
    25501 tacaaatatg tcatattttt ccttctgatt cttgaatgct tttgattcct tcttccaaaa
    25561 ttttcatttg taagattgtt tcttcatctt tgatgacttt ttctgcgcca ttaactaatg
    25621 tctcgtaaat cccttcgtag acacggctgt aatcaccaac ctcggaaatt actttttctt
    25681 catgataact cccttgttca tctatatagg tcaatacacc ataatgttcg ggcaaatcga
    25741 taccaaagtc ttcatgatca ggcatgtaaa acattttcag atgttcttct tgtcgatctt
    25801 ttgtttgttt cacgaacatc cctttttttc cgtaaacgac gaaacttgga cgttctttga
    25861 tgcggaaata actggatttt atcgaaattt tcatatttcc atagaaaaaa tccagatcga
    25921 agtaatcatt cattcgtcct ttccctaaaa gttgacgtac atcatagctg atatcatctg
    25981 gttcgccgaa ataagaaaga acttgatcta ctgtatgaca agcatgtcca tataaatagc
    26041 tgttcgcagt agaaaattca tgcgtatttt ctggtacttc cggtctgaaa taatcataat
    26101 gcatttctac ttctaaaata tcccctaatt ttccgctttc gattactttt tggactgtca
    26161 agaagtcaga atcgaaccgt ctgttttggt aacattggat aaatagacct ttttcttttg
    26221 ctaatgcaaa taactcttct gcttcctttg acgtttctgc aaaaggtttc tctactagta
    26281 cattcttacc atgttcgagt gccatttttc catattcata atgaaattga ctaggtgtag
    26341 tgatgacaac taattggatc tcaggatcat cccaaagatc agacagctga tcagtatatt
    26401 cgatgtcttc gaatgttttc cacactggtt cagatgggga aaaaattttt ttgatattga
    26461 ttttgttcgt aagttttctt gaaaaaggca aatgatagcg atttgtactc tttccattgc
    26521 caagataagc gattgtaagc atgagtggtg cctcctttta ttgatgtttt cagtatatcc
    26581 tagaaaagcg cagaaagtat ttataatagc tattctggta aaaaagttca gaaaaacact
    26641 tgttatcatt cggtttggtg aaattaatgt tcaaagtaag gataaaaatc aaaaagatag
    26701 tagcggaacc aagtgtttat cagtaagata gaatttggag gtcagatcat gcttattgaa
    26761 gaaaaactaa caaaacaaga gttgtttacc acgacagaga aacggattgt cgattacatc
    26821 cgtaggaata tcgaagctgc agtctacatg acgattgaag aattagcaaa agctacgtat
    26881 acttcccatt cagctatcat tcgtttatgc aaaaaaatgg gattcagcgg atttaaagaa
    26941 ttccgtttcg agctggggcg ggaagttcat caattgattg ctcagttcaa tcaaacgatt
    27001 gatcctaatt ttcctttttc aagtgaagat agcactcagc aaattgcaaa gaaaatggcg
    27061 gatttatcga tccagtcaat aaaaaaagca caattgcaga ttgaacatga agatttagat
    27121 caaatcggta aagtattgaa caaggcacag cgaatctttc tttttgcaaa aggtgattct
    27181 caaatcacgg caaggaaatt ccagaataaa atggtcaagt tgaataagtt tttgatcatg
    27241 gctgaagaat acagtgattc ttcttggaat gcagccaatt tgactagcga ggattgcgcc
    27301 atttttatta gctacagcgg tcgcatccat cattatgaac gaataatgac ctatttgaag
    27361 catgtagagg cccctacctt gctgattacc ggaaatcagc attcagaaat ggccaaacag
    27421 gctgatatgt gtcttgttat atcgcaggag gaatatgatt ttgctaaagt agcgactttc
    27481 tcctctcaaa ttgccttcga ttacgtatta aatacgttat tctcagtgat atattctcaa
    27541 aattttgaag agaatatccg caacttgaaa aacaaacaag aattgatgca aaaaggcctt
    27601 cttaaagaat atcggaaaac ttaagaaaag atcctcattt agtaataaga aagatagtgt
    27661 ttgataggct ctctttgata tcatcataaa aacaggctga agttttcttt ttcaaacctc
    27721 agcctgtttg tttacggaac gattcgaata gatatattat agaaatgagg aatagctaac
    27781 ttctgtttct tattttgaac gattgacgaa aaagatatat aagaaggagg aaaatcagta
    27841 tacatgcagc taacaatcca tacaggaaaa atcgtttgtt ctcggatact ttctgtactt
    27901 ctttttgaac ttcttttgca tgataaggaa cccggtgccc tctgacaagt aagcgatgac
    27961 tgttgaccat ataaggtgta caagttagga gtgtcacgaa atcctgccct ttttcgattc
    28021 tcagatcttt tgtatcagtc ggttctaccg tcttgatctg atcgacttga taagcgagtg
    28081 tccgtccatt gatttcgata tagaaagaat cacctaaagt cagtttcggt aagtctgtga
    28141 acaactttgc ttgaggcagt cctcgatggc tggaaataac ggcatgtgta ttttctcccc
    28201 ccgtaggata agacgttcct tccaataatg aggcaccttt ttctagcagc acagtattcg
    28261 tttcatcaaa aattggcaaa tggacattga tctcagggat cgtcaaaata ccgatcgtat
    28321 gtttctcaaa ataggttcta tcctttttcg caggttcttt tttcttagta aagggatctg
    28381 cacctggatt tccaccttct tttgctaatt gctggttttt ctttgtcatg ttttcttgga
    28441 ttttagccat gacttcttca ttttctttga ccgcttgttg ctgataatga gagatgatct
    28501 gctgatccag ataattattc agcgcgtcgc taacaaatgg ataagctagt atccctattc
    28561 ctgagagaag caagaaaagc atcagcagat ctagaagttt ccttttcttt ggtttcattt
    28621 gtgttctcct tgtgatgact gtttgataat aaaagaaaaa ggagcatttg cgtaatccgc
    28681 tgctcctttt tccaattctt gcaaaaagac taaatctgac tgtgcttgcg tctagcaaag
    28741 tacagtccag caatcagtag aaggactact cctgcaccga tatacacata gattccctta
    28801 ccgcctgttg aaggaagtgt acctttgtgt ttatttggta ttttttcagg agaaatcaac
    28861 tgtcctgctg ttacataaga ttgttcatcg atagtaaatg ctacacggtt tgttaatgga
    28921 acatattttt ctggcgcttt cgtttcttcc agatagtacg tgccatattt tagacctgtc
    28981 acatcgatta aaccgttact tgtggttgta aaaaccgttg ctgattcttt cgccgatacc
    29041 cagctgacgg cttttgtgga tgggtcgatc gataaatatt tcgctgtgtc actatcttga
    29101 tcacgaacga cgaattctgc tccagcaagt gtttggtctg atgtaacgtc accatctact
    29161 ttaacaaatc gtttgccccc agtaacgaca tcgactgacg gtggtgtttg atcatttgta
    29221 tgcccgttat cgacatttgc ttggttagaa aatcctttgg ttggatctgc tttttcgttc
    29281 aaatgcatat agtaaacgaa tttcaatgta ccgccaggag ttaatgaagg aatataattc
    29341 ggatcaactg aaaccgtgaa tccgtctgtt tgctcagtga cagaataatt tactgggtcg
    29401 atttctttat ttccatcata taaggcataa gcatacgttc ctgaagaatc attatcaaat
    29461 gttaaagcag cgtcatgagt atcgataagt ttgaatgttg tgtacttgtt ttgcgttcct
    29521 tctttatcag cgatacctaa tgggatattg acagaaatct catattgaat tttttcaccg
    29581 attgcgacat cttttccatt caattgaggt gttgttttat caactttaga cgtatcattt
    29641 ttgatggtct tttctactgg tgtttggcta tttgccagga tctcaaaagg cgtgattgtt
    29701 tgcttttcaa tcatttccgc attatcagga gcttttactt cttctaaatt atattttcca
    29761 acttctaaat gattaacgat caactggcct ttttcaatag atgcctcggc aaagtcattg
    29821 ttgccgatgt cataagaatg accagtaatg aaatgtttgg ctttggtttg atcagttgtc
    29881 caagtgtaca atccatctgt gacactttgg atgtattttt tgacgcttgg tgttccttct
    29941 tctttagaaa taataaattc tgctccattt agtgcttcgt tttcggcagt accgattttt
    30001 gtaactttca acgttccatc attaccgact gtatttttag ggtagagatg gatagtatct
    30061 agttcttctg tcccgtattt ataagagcca tctgcttgtt tgatcatctc atatacaggg
    30121 aaagctaaaa ccatgtttgc ggcagctgac actccgtctt ttggttcttc tttgatcgtg
    30181 tagactgcat ctttcccatt ttgtttttta ggtaaagata aagtgacatt tccatcagca
    30241 tctgtcgttc ctgaagcaac tggtgtacca ggagtcaaag actggactgc ttgttttgct
    30301 gcatccacgg acgctccttt atctcgttgc gcataaaatt cttgagtgac gttataaact
    30361 gaaaatgaaa tatcggctaa tccttggtat tgatcgaatt cgctcatttc tttcccgctg
    30421 ttttggatta aaggatcggg taaatcagtc attttctttt tatgaaggat gacttgagct
    30481 gctgtctcct ctgcaaacac tttttttgcg ccgaagctgt ttgtgagtaa tggtaaaata
    30541 aggaaaagga ctcctaacat aacgtttatt tttttatgat ttttcatttt ttcactcctg
    30601 ttcttttttt gataaacaac cagattgcaa agcttgcgaa taccatacca acaacgccta
    30661 aaagtgtatt tttcgtttcg tttgtttttg gaagaaatgg acggctattt tcttttttat
    30721 tgactacttt caatatactg tccgcctctt tatcctcaga aagaaaagtt gaaatggtaa
    30781 acggaatttc tgtttcactt aaaatataac cagaaggtgc ttcgatctct tttaatcgat
    30841 aacttcctgt tttcaacccg gaaattgaaa aagcgccatt tttatcggaa atcaggtgaa
    30901 gcgcatctga ttcgttcttt gtccacttgt atccgttggc tgtttgctgg aggtaatttc
    30961 ctgctttgtt tttaataagg aatactgcgc cagctaatcg tttatctggt ttatttgtct
    31021 cgattttgac aaattgctta ctccctgtat atacagagac tttctttgta ctgacaccaa
    31081 aaccaaaatc cagtgttccg ttgttgttga tttccttgtt cgcctgtgct gtactgctta
    31141 gctgcatctg ataagaaatg gtcagttttt ttccagcata tttttccaac gaagggatcg
    31201 aaaataaaac atcaaatccg tgaggtttct tgtgtatgac aaagccttct gtcagctttt
    31261 ctccattcga tgaaatcgtt aaactattag gtaaaaacgt taatgcttca tccgcactat
    31321 ctgacaattc gaacttttga tagtcaagga tatttacagg aattgtcgta tgcaaggaat
    31381 aagtgatttt ttcaccaatc gtaaaatcat ttctaggctc ttctaatacc ttctcaaaag
    31441 gtggatcagg gtagtcgttt tcttcatttt taggatacaa atggatagtt gaaagttttt
    31501 gattgttttg tccatgtaca ggaagaacaa ctaccatatt ctctgccttt tctttgacga
    31561 cttctggtac tttggattca atgaaaagat acgctttatc tcttttttct tgatctttag
    31621 cggccagaga aaaagaagcg ataccatctt cgttgttaag agttgtagtt gttgcttctg
    31681 cggtaaacat accggaagac gcaccgtttt ttgcgatctc tgcttgtgct tcttctaccg
    31741 ttttgccctt ttcccgtaga tggtaaaaag aatctgtgac atcataaact tggaatgtga
    31801 caccatttaa tcctcgatac gtttgtaata aagctttttc ttgtccgtca tttggatgat
    31861 ttttcggcag ttgcccgttt gggaaaagca atttgtgtaa agtaatctga accatttctg
    31921 tttctgtttc tgttgctacc tgagtaaaag ctggtttaaa tagtaacaag aagagacaca
    31981 tactaagcca accaagtttt ttcatattta gctgccccct ctttcttttt tcaaaaaaag
    32041 ataccaaata gaaaacgcac aaccaatcat ccctactaga tagattccta aacggccaat
    32101 tcctcccgtt tcaggtaatg gtacttttgc ctgattcgtg atgtctaaag aaatctggtt
    32161 gtttttggct cctggtgaca gaacagattc atgatcttgt ccatccactt gaattgaccc
    32221 atcttcgtgt ataactatag taactggctc ttttagacct tggtatcctt ctggtgtaaa
    32281 agtttcggtc agcgtataag ttccaggttt taaattttcg aatagaaagg tatctgtttc
    32341 ttgtccatct tttggcgatt ctaagtccat ttctggtccc tgcagtctga attttgctcc
    32401 ttttaatgtc tgtccgttgt cttctttttt gtgtaccgtt agatcaaacg cttttagtcg
    32461 attttgatga gtgagcgtcc atacattatt tgtcatctcg gtattttttc ccgtgtaaat
    32521 gatttttcca tatttatcga tttggaattc ataatttccc ggcgaagtat catatccggc
    32581 aggaccagct gtttcaacga ctcgatattt accaggtgtg agtgaatcaa aactggcaag
    32641 acctttttca ttcgttgttt ggctgtcaat tggctgataa gtaccatttg cttctttttt
    32701 ctgtagggaa aatgctgctc ctttaagatt tatctctttg tccgtccctt gcatcgcata
    32761 cttacgtact gctacaggaa cttcaacaaa aggattttca atagtcaact ggatcgtatc
    32821 atcggaagta gtgactgttt ttccatcaat ggttaccgta ccatcagaag cgatcttgat
    32881 ttcccaagta gtctttttgc ttaatccatg cccttctgga gcttttgttt ctgtcagcgt
    32941 ataggtcatt tctttttgca atttgacatt ttctggaaga gaataggttc cgtcgccatg
    33001 atctgttagt aaagtatcaa tagaatctcc tgttaatttg aaaacagcgc caataagatc
    33061 cttttcacct gtagaggaat ttttcgttat tttcaagttt aacggtgtga attgtttagt
    33121 atttttccat gtcattgcat ctatttgttg agaatcgtat cctggtacag gtaattcttt
    33181 gattgtttgg taactgaatg cttgaccttg attattgtat tgaggtagtg ataatatctc
    33241 ttgataactt tctccgctat ttgcagataa tttgtcaatg tctgcacgtt cccacgtatt
    33301 tgttgtatct ttagctggtt taatgattcg aatatatccg tttttccaag ctgcagcatt
    33361 tgtcgtatgt tcccgttgaa tctcaaaagt aacttgatct ggacgatcag ctagattgtt
    33421 gtcaaattct tcccataact ttttgatgtg aagactgact ccgggagctt tagcagatgg
    33481 tataccgaat tcagctaatt cattggtatc aatgtttggc tggaaagttg tcctgccgtt
    33541 catttgatac cagaaatttg gatggaagtc ctcattttct gtttggattc tcacttggta
    33601 atggatttgg atttcttggt cttttcctaa atagatctga ttgctcttga tggtatttcc
    33661 ttctatggaa atagatggag tgaccgttgt aggacttgtc cccacactct tgactgaaag
    33721 tgtaccaggc tgataaatga atggttctgc gattggatca tttatttgtc cattgcttac
    33781 agttgctgag atctgtacag cttttttggc taggtattca gagatatctg ttgcatgatc
    33841 agctgattca tagtaaagat cgcctttttc atctgatgaa accatttgtc gcatacgaga
    33901 ctctacttct gcttttgaga gaccagctgc cggatcgctt tgaagttgga tgccaagacc
    33961 atgtatttcg attcctcgtt ctttgagtgc catcgcttct ccgatggttg cgataaacgt
    34021 actgtcgatt cttctggata gattgttttg gtcaggtgca tcatagattc ttgagattag
    34081 agaagtattt cccggccgat cttgcgtatt agaaaactga gttccgtaat aattgctgct
    34141 tgattgtgcg tgtacccgct gtactttata ggaaaatgtt ggtacaccat ccgtcagcaa
    34201 aacgatcact tttttatgtc catttggaac ggatagcatg cttcctgcat ctcttagtgc
    34261 tttttgtgta aaagtaccac catttgtccg tgaaggtgta atggatttta cttcattttt
    34321 cactgaatca aatgaaccca tctgtactgc accgttactg tagctatatc cttcgcttga
    34381 gtagccgaca tatcccatat tgattttgtc tgtgataccg ctatctgcta aagtatcgac
    34441 aaaacgatcg acaccaatct ttacttcacc gatccgatta ttgtcgttca tacttcctga
    34501 ccagtctacg accaatacga gatcaagagg cgtgatatct ttttgtacat ttccacgagc
    34561 attcaaataa acatcaaaca atccgggtgt acttgtttcc tttgcatact ttcgtatcgc
    34621 atagtctgct tgattaccgg ttcctccata ttcgatatac gaatgggtcc gatcattagg
    34681 atctccattc caagaattta taccatccca ttgatttgtt ccgtttttat tgccttgatg
    34741 atcaagaaca tttgtatttc ctgtaggttg ccaactggct ttaggataag tgccctgatc
    34801 atctgttgta tattctgtag gaatcgtttg attagatggc acactcacag ctggcaagga
    34861 taatgtaggc aatgtaaatg ggctgacaga attttcgttt tcttttgatg attcttcttc
    34921 tatttcgtct ggctttggta ctgacacatc tgtatctttc ttattttctg tctcatcaat
    34981 aatgtcatat tctttattat cgacgatcag cttgtttgcc tggctgtggt aaagtgctgg
    35041 atcgattgga aaactcagat cgatagtttg tttagtgttt gatgagattt ccaacgtaat
    35101 tttcccgcta tttacctgat aagcatagcc atctccttct tttctttcca catcacttaa
    35161 gtaattttcg actagaccaa tttctttttc tatcttttca gcactggtgt tattcgcatt
    35221 tagcttgatg ttcagtgctt tttttccaga ctgatccgaa atgacttcag ctgaaattgt
    35281 ttctaaaact gttggatcat ctgtagtgtc tgctattgca gataatggca caaagtttga
    35341 taaactcaat attatcagca tgaaaataac tttcagtttc ttccctgtgg tcgtcatttt
    35401 tcccctcctt tttctttttt tctgttttga cgtgaatagt gaaaattatt aaaataaaca
    35461 ggcgttacat aattttattt attttaatat gataattatt atacgaaggg cgctaaaggg
    35521 aatcacacca attttcatac caattggttt catttatgaa gttgattcct tcgattaatg
    35581 agcgtttcat tgaaagaaaa gggttgaggg agaaaaacat atgatcaggt tgttggaacg
    35641 aaactataga aagatggaaa aaatcattcg aattctgtcc atttctgaca agtggatgac
    35701 taaaaaagaa cttgccaaac gaattggtag ttcagaatct acatttgtaa ggtatatcga
    35761 agagatcaaa atccgctggg gaacggatgt aacgattcaa tcttcacaaa aattggggta
    35821 tcgtcttgaa catttgaatg taccagctta tttaaatgtt ctgatggaaa tgtcgcaaag
    35881 ttctacaaac ggtcgtttat taaatgagat tattgtcaat ccgggtaaaa cgattgagta
    35941 ttattgtgaa aaaatttcca tcagccggtc ttcttttaca cgtaagttga aacaatgcaa
    36001 tcaaatttta gaaagctatt tattaaaagt gatcgttgac caaggttttc agttaactag
    36061 ccttaaaagt gagctccagt tgcgtatctt tgttaccttt ttctttttaa gttactacgg
    36121 aagacgcacg ttgccatttc caatcgaaaa aaagaagatc aaagaaatta tggtcaagaa
    36181 taattgtcag atgaatttgt ttcaggaaga aagcccatat gagcaatctt tctttattat
    36241 gtattttgtt gtgcatctca tgagagaatc ccaaggaact ccatttgaat ggaaagctgg
    36301 agactcttat gtacagttga taaatatcga taaaaaagac ttcttaatct tgaaaaatct
    36361 cttaggaaaa ttgaagtaca gcagctatat aaaagtagtg aactattttg tcaatacgat
    36421 tttttcagaa ttttcggaga aagaaaaaaa tgaaatcagt gagcagatac gaaaaaatat
    36481 gtcctactgt tcgttttcat ccgctgattg caaagaaaaa aacgaagaat atgttgttca
    36541 attattaacg caaatttatt ttttctcccg tattttccca tacgatacga ctcatttgac
    36601 gatccgtgca acttactttg cacagcagat gcaacaccgc cagatacgtc tatatgctgg
    36661 atttcgtgca gaacttcaat tttattccac tctactgaat cagaatctga tttattattt
    36721 atctagctat atcttttgga tgcttatcgg taatcctgaa attcaccatt atacttctga
    36781 taaaaaaata ctgattatca gcgacttaag tcttcgacat agtcaatata ttgaagaata
    36841 tatcagtgat attcttgctg tgcataaaat tcactctgag acaactgcta ttactgaaga
    36901 tcagctgtcg aaatacaatc ttctcgagta tgatctgatc gttacgaatc aacccatttt
    36961 gaatgcccat gttcctcata tattgattga tgatagtgtg tcattcgcaa atgaagaaga
    37021 actcatccgc ttattcgagt tatgaataat caaaaaacag ctatgtataa accaccctga
    37081 taaaaatttc aggacaaata cacatagctg tttcttttta ttgtattcct tcagcaatcc
    37141 aacgagattt atagcgaaag tcttttaaca actcttcttt tgtccaatta tttgcaatga
    37201 gatccgtcaa agtgttcatt acgagggtca tggaaaagta taggaaacta actgcttctt
    37261 ccgacgattg aatggagaaa tgattgattc ttaataattc cagccatttt tcgttcattg
    37321 gagaatcagc cgatagttct ctacgtttgg ttgtctgctg atcatttcgc tgggttaaca
    37381 agtataacct ttgccaatag atactttcgt gatctaagtc gcagcaccac tctaaatatt
    37441 tttcgatccc caaaaagaaa tgttgtttgt tttcgctaat gaattttaag atatcttgat
    37501 ggactatgtg agaactgctt ttgatcgtat acaaataagc atcttccaaa tcttgaaaat
    37561 atttataaaa agcaccgcgc gacatcccca tcttgtcaac gatttctgag actttgactt
    37621 ggctgatgtg ctgtgagcaa aatatctcca gtaataggtc atcgattctc tgtttctttg
    37681 cgttcgataa attgaaaaaa gtttcttttg gcatccacat ctctccttta tctctgatta
    37741 tacgtggata gcccttcatt gtcatgaagg attcattcct tctttttctc ttcttctgtc
    37801 aagtacccat cttccattcg ataaacgcga tcactccatt gaatcatacg gacatcatga
    37861 gtaaccataa tagtcgcttt ttgtttctca tgagcttctt taactagtaa tttgacgact
    37921 tcatatgcat gatctgtatc caaactagct gttggttcgt ctgctaagat caagcttggc
    37981 tcattatata aagcgcgagc aattgccact ctctgtcttt ctccaccaga aaggtcttta
    38041 ggataactat ttttaagtga ctggatatct aaagattgca gcaaggaatc gatttttgtt
    38101 gaatcttctt tttttgaagt aacttggtca actagttcaa attgttcctt taccgttaaa
    38161 aaaggaatca aattagagct ttggagaata aatcctattt ctttaaagcg taaatctgct
    38221 cgtttttttt ctggaagctc agttagtgag tgaccgttga tcactatttc tccggaagtc
    38281 ggtgtttgca atcctcctga aatggtaagg aaagtacttt tacctgaacc agaaggacca
    38341 atgatgctga cgaattctcc ttcctttaca taaaaatcaa ttgctttcaa agctgagacc
    38401 tttgtatgac cagaaccaaa tgttttggta acttttttca tcgttaatat ttttttcatt
    38461 tttattaacc tcctattgct gtaattgggt ctactttggt tatcgtacgt atcgaaaaca
    38521 atccgcctag cattgcgaca atgatcaaaa tcccactata tagcaaccat tgtgaccaaa
    38581 aaacagcaaa aggcatcgcg cttggtaaaa tcagactagt caaataagca aacaaaagag
    38641 caagcagaac gcctaccacc ccaacaataa aggactgtgc tactaaagat ttagcgatga
    38701 agaaattttt gatcccttgt gctttcatta ctccaaaaat agcagtcttc tgaagtgtca
    38761 tcacgtacat gaaaataccg accacggcag caaccactaa gaacaaaaag tatatcatcg
    38821 catttaaggt catattttgg gcagaatagc caggaatact ttcaatgaat gtcccaatag
    38881 ttaataactg tagacccttc gatgcttttt ctttcgaaat tttagctgaa tcctttatta
    38941 cgatcccatt gatcggctgt tcttcttcag aagcaaacgg ctgttgtcca tacttcaaag
    39001 cagtccacgt atctagggac gcatagatga cgggagaaac tgtgtaataa gtttcaggaa
    39061 agataccgac aatcgtcaaa ggatcgtcgt aactgccaat tttgatcgta tctccaattt
    39121 tatagcctga atcagccaga ttttgagaga tgatgatttc attctttgtt ttaaattcat
    39181 gccctttcgt gagttttggt aataaaaatg cttctttcgt tgtgccgaaa actgtaacat
    39241 tttctttgtt ttttcctttg attgctccgc tgtacaatcc gattggtgct ttctctcctc
    39301 cttcaatgta tttcagatct cctcttgtta attgtgaagc tgcaaatact tgatttgcat
    39361 cctccgacaa aacaatctct tgtgcgtccc aatcatcgat tgctttttta aactcttctg
    39421 aaagtccatt cgctagtcct gacaacatga atacgacata cgcaatcaag aacataatac
    39481 cgacgatcaa gccatatcgt aatttagaat agcgaatttc tttgatagct agaaacattt
    39541 gtttttcctc cctatgatag attgatagtg acaaaatgtc acttgttgaa tagtgtaact
    39601 ctaaagtgac aatttgtcac ttgtgttgtt tttttcttat caataaattg tctaagacat
    39661 ctttcgataa aaccttaaca tgagtcataa aaaatttatt taagccttat ttatgctttc
    39721 catgataaac taaagtgacc aaatcaatga ggtgggaaaa tgattaaact attagtagta
    39781 gaagacgata aagtattatc caataatata aaagaaatac tcgctgcaat cggcgagata
    39841 acacaagttt atgatggtag tgaaggactg ttcgagttgg aaagtggagt ttatgatctt
    39901 gcaatcttgg atttgatgat gccggaaatg aatggatatg aagtgttagc aaaaatacgg
    39961 aaagaaaaaa tacagactcc agtattgatt ttgactgcaa aagatagttt ggaagataag
    40021 attgaaggat ttgaacgagg tgcagatgat tatctaacaa aacctttcta tcgagaagaa
    40081 ctgatcatgc gcgtgaaagc attattgaaa cgctcgctag gtctctttga tgaaaatgtt
    40141 ctgaagtata aggatatcag ttgtgattta aaaagcaatg aagtcttgta taaagaacaa
    40201 gttttgccca tacaaggaaa agagtttgaa ttgctcgttt attttttaca aaataaggga
    40261 atcattttga caaaagagca gatatttgac cggatctggg gatttgattc tgatacgacg
    40321 attacagtta ttgaagttta tatgagcaac ttacgaaaac atctgcgaag tactggattg
    40381 gataaagaaa tcaaaacctt acgtaatgtc ggttatatac tgcaaagggt gtgatgcaat
    40441 gaatggagat attacacgaa agcaacgtag tcgctttttt gcgacaaatg tagcagcatt
    40501 tgcttttatc ttttttcttt tgggattcat tactttacag atattaaacc aatctgcata
    40561 cagagaaaca gatctgtcat tagagaaaat aaattttgat tctcgaacag tacaattaga
    40621 gatacaaaga tatcagcaag gcgatccctt tttaaacccg actcaaacgg aacaaaacag
    40681 aacaaacatg gaacagccat taatggaacc atcaaatgac cgttttaaca ctcaagtgat
    40741 cttgtggtct aaaaatggtg agatattgaa taaagcagct attggtgggc gtttcaacca
    40801 aatcaaagaa ttaaaaatgg atacgaaaaa tctgaatacc atccaaaata ttgaattaaa
    40861 tgaagacagt ggctcatctg ccctctcttt ccgttcgatt acgaaaaaag cggagacgaa
    40921 tcaagatggc gttgcctaca tccaaatttt agaaaataca aatcaaatca agaattcatt
    40981 agcgactttt cgcacgatta tgattttgtg tatgattgtt ttttggattc tctctattgg
    41041 tatcagttat tacttgtcta gtctaagcat gcgccctatt attctttctt ggagaagaca
    41101 aaaagaattt gttgagaatg cttctcatga attgcgcaca ccgttaacga ttattcaaaa
    41161 tagtttggaa catcttttta ccaagcctaa tcatactatt attgaagaat ccgaaagcat
    41221 cgctcaagca ttgtcagaga cgaggcgcct cactggattg acttcggatt tgctgacaat
    41281 cgctcggaat gattctgatc agcagctgct ttcaaagcaa atgatcaata cacaagaata
    41341 tatcgaacaa cttgttaaac catttcaaga gatggccatc atagatggaa aagagtttat
    41401 tctccataac gatgcaacat tagaagtacc aattgatgaa aaaaaaatcc atcaagtttt
    41461 ggttattttg ctggataatg cattaaaata tacgaatcca gaagataaga tcattttgga
    41521 ttcatctgtt aaccataaag aatggctgat tcacgtaaag aatactggcc cttctatcag
    41581 tgaagaagat caagcaagga tttttgatcg attttatcgg gaagatcaat ctcgggcgaa
    41641 agagactggc ggatacgggc ttggcttggc aattgcaaaa caggtaatcg aacagcatca
    41701 tggacagatt tctgtatcca attatcttcc acaaggagtc gattttaaag tccaattgcc
    41761 gttgaagcct aaaaaataat gcttatccct aaaaaagggc tgtgacaaaa atcttgtcac
    41821 agcccttttt tgttgcgaat aaacggtgtt ccagaagtag cttcttcgga aataagccga
    41881 aatttcttta agctgaccac ttctgtcaca acctctttag cttacgctta cgatttttta
    41941 ttgcggtctt caatgtgtac atcaccgctt gtgtcaatat ccaattcttc tcggctaaca
    42001 tcttctgtca ctttttcaac atcttcatgt tcttctttat gaatcccaac ttcttcacga
    42061 ataactgtat gtttgcttac atctacttgc tcttctttga ttgggatagt aatcgtgtca
    42121 tcttccaatt tttcgtctgt tccctgtgaa gattgatctg ttactggttt gcgttcgatg
    42181 acgatttctt cacgtttgac cggtacttct accgtttcag tatcgttgac cacatgtttg
    42241 tggatgtcga cttctccagt tgtcacatca tgtgtattta catctaattt ttcttctttt
    42301 agttgaattg tatcatcatc tagatttggt ttgcgatcga tgtcttcagt cttgcttgta
    42361 cccattgtat cagtctcgcc aggtacgtcc atcggatcag ttcctggtgt catattcaat
    42421 ggatccgttg tattttgaaa gcctgtcgtg ccacctacgt ccattggatc tgttccagtg
    42481 ccagtttcta atccagtccc cattgtgctt gctgggctaa cagtatcttg tgtatccatt
    42541 gtatcttctg ttgtttctgg ctgacgatag ccttttactg tgatgacaaa ttttccatca
    42601 gaaatatctc ctctatattg atataaagga tcattttctg gtgtagccgt ctcagaatca
    42661 taggtatcaa aagaaaaagt atcttttatt ttttcccata aagaacggtc ttcttcacca
    42721 tccatccgat tttcatctgt ttcaacatct ataccagaca atccgtcaaa tcctagtcta
    42781 gatgctgctt catcagtagt ataaataacg atatcatctc gttcataccc ttcgttacgc
    42841 aaccgttcaa ttactgataa tgcttcttcc ctcgtactat agcttccgat gaccgttaaa
    42901 tttttctctt ccatgtaaat tcctcctagc aaatagattt atgattggta tattgttact
    42961 tataaattta ttctatagga gacgattgtt ttctacaaat atttagattg gaatttgatt
    43021 aaaacaattt aattgaaatt tgaaaacatt tatgttaatg aaagtcatat tctaataaaa
    43081 tgtcatttgt ttctatatga atttttatga aaaatttcat ataatttcca ctcgttgtga
    43141 tggtttaatt tatccaatcc atcaataagc aaacaactta tataaaaaag gattaattct
    43201 caatataatt gctcctacca tagaataaat cttcatgtaa agtaatgaag taccaactat
    43261 ttctaatact tctttaagaa ttatcccaac aatatcgtta gacaaaccat tattgaataa
    43321 atggagagcc aatcgattct gaaaaaatgt tttctaattt ttcggaaata aaagaaagag
    43381 cctcctgcca ttagaacgaa ccaaatccat ttcattgctc atgaagtaac cacatagcta
    43441 aaaagaggat aaatcaatta aaagatcaaa agaatgactg cactaataaa ataactaaaa
    43501 atgtatcttc ttacttcata tcttttagct agtacttagt taaaaatttg cttcctaaga
    43561 tcaagacaaa ctgtctatct tcatttgatg aaatgcggta aaatatagaa aatgaacact
    43621 attggaggga atttgtaatg gacagcaaaa ctagaaaaca actgcaagaa aagttaaagc
    43681 aacgtacaca cttgctccct tccgtctttc aacagttttt agaagaaaat cgttcttccc
    43741 tttcattagg cagtcgctat gaatacgcaa aagattttca tctgtttact gattatttga
    43801 gaaaagtatt ttctgaagaa gtggatgatc agctgattat ccatttagaa aaacaagatt
    43861 atcagaattt cttagctaaa atctatcgac atactcgttc gttccaaact acagcgaacc
    43921 aagaaacgga gcaattgttt gaaaatagct attacgggat ttcaaggaag caatattcat
    43981 taaatcattt tttacgattt ttgtatcaaa aaggactgat tgaagaagag atttctcttt
    44041 tgggtacaag tttaccggaa acaaccaaag cagctccgcg atatatcgat gcagaacttt
    44101 tcaaagattt tgagcatttg tttatcccga ttgaaggctt tcaaacaagc agagaagcta
    44161 gctttgaaga aaagaataga ccgaggaacc ttgcaattac tgccattctt ctgtattgcg
    44221 gattaaagat ccatgaagta gtagaactta aacgtaaaga tgtatctttg accaagcaga
    44281 ttcttaatct gaatagaaaa gaaaacagac tgaataaagt accaatacca aaagaagcga
    44341 tgccatttct ggagaactat tttaagttaa cagcacaaaa tacggacgaa aattcttttg
    44401 tttttcgttc ctcacatgat cagcaaattt ctcctcggac tattcgccaa attttgagca
    44461 aaattacagt atataaaaac gtatcgccag aactatgcag aaaaacatat cgttattatg
    44521 cagaactata tttagatgat gctgacgcgg taaattattt atgtggtaat cgatacctct
    44581 catcccattc ttttcaagat atctgggaaa agatggttga tttttcttat cacgaattag
    44641 cggcattcgt tcgggtttct tccatataaa acaaatgtat gatctttttt tcacaataaa
    44701 ctatgttatt atataaagga ttatgttacg attatcttga atttgtatat tacttaacaa
    44761 aagataatgg agtgtgaatg atggagacca taacgtattc ccctttgaac ttatttacga
    44821 attttcaaga agctgcagct aacttttccg agaccccgat tatctttgat gagccacttt
    44881 cagctttccc agaattagga cttgaaacaa cttacaaaaa atgctgcgaa agtgtgttga
    44941 aacgggctta tcaattggct catcttggag tgaaatccgg agacaaagtt attatttata
    45001 agagttccgc ttttgacaca taccttctag ctgtttctgt gtcttacctt ggtgcagtgc
    45061 ctgtcatgac ttcttatcat ctaccaacaa caacaatgga agtatttatc gatcgtttag
    45121 aagacccttt cattttattt gatgatgaga caaaaaagcg agtgagagaa atttcaaatg
    45181 gaacaaaatc aaaacagatt c
//
LOCUS       DACDLM010000017        44050 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.017, whole genome shotgun sequence.
ACCESSION   DACDLM010000017 DACDLM010000000
VERSION     DACDLM010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44050
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.017"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            259..597
                     /locus_tag="IV356_000959"
     CDS             259..597
                     /locus_tag="IV356_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014665.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(802..1041)
                     /locus_tag="IV356_000960"
     CDS             complement(802..1041)
                     /locus_tag="IV356_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
                     /protein_id="HAP9014666.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(1017..1364)
                     /locus_tag="IV356_000961"
     CDS             complement(1017..1364)
                     /locus_tag="IV356_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF159 family protein"
                     /protein_id="HAP9014667.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(2096..2677)
                     /locus_tag="IV356_000962"
     CDS             complement(2096..2677)
                     /locus_tag="IV356_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP9014668.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(2860..3486)
                     /locus_tag="IV356_000963"
     CDS             complement(2860..3486)
                     /locus_tag="IV356_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP9014669.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(3508..4839)
                     /locus_tag="IV356_000964"
     CDS             complement(3508..4839)
                     /locus_tag="IV356_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HAP9014670.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(4994..5395)
                     /locus_tag="IV356_000965"
     CDS             complement(4994..5395)
                     /locus_tag="IV356_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAP9014671.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(5481..5687)
                     /locus_tag="IV356_000966"
     CDS             complement(5481..5687)
                     /locus_tag="IV356_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014672.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(5782..7284)
                     /locus_tag="IV356_000967"
     CDS             complement(5782..7284)
                     /locus_tag="IV356_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HAP9014673.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(7302..7757)
                     /gene="argR"
                     /locus_tag="IV356_000968"
     CDS             complement(7302..7757)
                     /gene="argR"
                     /locus_tag="IV356_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAP9014674.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(7855..8472)
                     /locus_tag="IV356_000969"
     CDS             complement(7855..8472)
                     /locus_tag="IV356_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014675.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            8693..10066
                     /locus_tag="IV356_000970"
     CDS             8693..10066
                     /locus_tag="IV356_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAP9014676.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLILSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            10141..11253
                     /locus_tag="IV356_000971"
     CDS             10141..11253
                     /locus_tag="IV356_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HAP9014677.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(11325..12962)
                     /locus_tag="IV356_000972"
     CDS             complement(11325..12962)
                     /locus_tag="IV356_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HAP9014678.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(13130..13738)
                     /locus_tag="IV356_000973"
     CDS             complement(13130..13738)
                     /locus_tag="IV356_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP9014679.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(14122..15273)
                     /gene="queG"
                     /locus_tag="IV356_000974"
     CDS             complement(14122..15273)
                     /gene="queG"
                     /locus_tag="IV356_000974"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HAP9014680.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(15292..16044)
                     /locus_tag="IV356_000975"
     CDS             complement(15292..16044)
                     /locus_tag="IV356_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014681.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(16185..17135)
                     /locus_tag="IV356_000976"
     CDS             complement(16185..17135)
                     /locus_tag="IV356_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAP9014682.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(17136..17975)
                     /locus_tag="IV356_000977"
     CDS             complement(17136..17975)
                     /locus_tag="IV356_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAP9014683.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(17972..18718)
                     /locus_tag="IV356_000978"
     CDS             complement(17972..18718)
                     /locus_tag="IV356_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAP9014684.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQPVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            18956..20326
                     /locus_tag="IV356_000979"
     CDS             18956..20326
                     /locus_tag="IV356_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP9014685.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(20381..21277)
                     /locus_tag="IV356_000980"
     CDS             complement(20381..21277)
                     /locus_tag="IV356_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP9014686.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(21558..22235)
                     /locus_tag="IV356_000981"
     CDS             complement(21558..22235)
                     /locus_tag="IV356_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAP9014687.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(22326..23231)
                     /locus_tag="IV356_000982"
     CDS             complement(22326..23231)
                     /locus_tag="IV356_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP9014688.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            23406..24830
                     /locus_tag="IV356_000983"
     CDS             23406..24830
                     /locus_tag="IV356_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP9014689.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMED"
     gene            24876..25907
                     /locus_tag="IV356_000984"
     CDS             24876..25907
                     /locus_tag="IV356_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAP9014690.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            25914..27101
                     /locus_tag="IV356_000985"
     CDS             25914..27101
                     /locus_tag="IV356_000985"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HAP9014691.1"
                     /translation="MEIKRSLNTKFAEIFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            27257..28639
                     /locus_tag="IV356_000986"
     CDS             27257..28639
                     /locus_tag="IV356_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAP9014692.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            28611..28997
                     /locus_tag="IV356_000987"
     CDS             28611..28997
                     /locus_tag="IV356_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014693.1"
                     /translation="MRRTAKKFIDYNEYRDRPFGLKWGTAFAMEELVNGIKKNEEEAR
                     KQPLPKQQMTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYF
                     MIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(29197..29865)
                     /locus_tag="IV356_000988"
     CDS             complement(29197..29865)
                     /locus_tag="IV356_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HAP9014694.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(30054..30851)
                     /locus_tag="IV356_000989"
                     /pseudo
     CDS             complement(30054..30851)
                     /locus_tag="IV356_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(31132..32511)
                     /locus_tag="IV356_000990"
     CDS             complement(31132..32511)
                     /locus_tag="IV356_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAP9014695.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            complement(32686..33855)
                     /locus_tag="IV356_000991"
     CDS             complement(32686..33855)
                     /locus_tag="IV356_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAP9014696.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            complement(33830..34981)
                     /locus_tag="IV356_000992"
     CDS             complement(33830..34981)
                     /locus_tag="IV356_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAP9014697.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            complement(34941..36302)
                     /locus_tag="IV356_000993"
     CDS             complement(34941..36302)
                     /locus_tag="IV356_000993"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HAP9014698.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            complement(36299..37300)
                     /locus_tag="IV356_000994"
     CDS             complement(36299..37300)
                     /locus_tag="IV356_000994"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HAP9014699.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            complement(37316..38011)
                     /gene="dapD"
                     /locus_tag="IV356_000995"
     CDS             complement(37316..38011)
                     /gene="dapD"
                     /locus_tag="IV356_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HAP9014700.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            complement(38017..38733)
                     /locus_tag="IV356_000996"
     CDS             complement(38017..38733)
                     /locus_tag="IV356_000996"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HAP9014701.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            complement(38730..39611)
                     /locus_tag="IV356_000997"
     CDS             complement(38730..39611)
                     /locus_tag="IV356_000997"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HAP9014702.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            complement(39614..40414)
                     /gene="dapF"
                     /locus_tag="IV356_000998"
     CDS             complement(39614..40414)
                     /gene="dapF"
                     /locus_tag="IV356_000998"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HAP9014703.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            complement(40401..41660)
                     /gene="lysA"
                     /locus_tag="IV356_000999"
     CDS             complement(40401..41660)
                     /gene="lysA"
                     /locus_tag="IV356_000999"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HAP9014704.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            complement(42146..42709)
                     /gene="efp"
                     /locus_tag="IV356_001000"
     CDS             complement(42146..42709)
                     /gene="efp"
                     /locus_tag="IV356_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HAP9014705.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            43137..>44050
                     /locus_tag="IV356_001001"
     CDS             43137..>44050
                     /locus_tag="IV356_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HAP9014706.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNHTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIY"
BASE COUNT        12276 a         9179 c         7922 g        14673 t
ORIGIN      
        1 tatataacac taagtaacgc aaaattcccc tttgtaaact atctagaaaa ttgttttgtt
       61 taaagtatat cttattggat ataaatagaa ataaattgta gccagttcat tttttcttta
      121 actaaaaaaa taatccaaga aacattgaac ctatggatcc aaaagctacc caaatactat
      181 agctaacccc ccgctacctt caattttgca gataaaacgc tttgggagaa aatttcaaag
      241 acaacaggcc atcctatcat gcccgattat aaacaaaaag ctggctattc cttttgctct
      301 gacaaatttc aattgggaaa gttcacgaaa ctagcaggtg aagaagtttc aactgttcgg
      361 atcaaagaat gcccgcttca aatagaaaca ttggttcaac gaatttcaac tagacaagac
      421 tttgctattg tagaacgtga gatcgtagct atttttgtag aagaagggat tttacatgat
      481 ccaactcata tcaatgtgga taaatggcaa cctcttatct ataaattcag agaatataca
      541 actgccaacc agtcgttaac tttgaatttt agattccaag aattcaaaga gtcataatga
      601 taaacatcgt taggtataaa taaaaaagac tcgcagcacg agtaaaaaac aaatagaagc
      661 tatacattag aaaggtcgac tgtgacccta tagatgcagt atatgcagct tatgagcatt
      721 tcttctgttc tctttgtttt tgggatctgt gctgaagtct ttttcgtttt ttgccgctct
      781 ttctttgaaa aatcgattat gttatacctt ctccattact aattcaggca tctgctgagt
      841 aatgattttt cgcgcaaaag aaatatctgt tacccaaggt tcgatttgtt cttcagtcaa
      901 gacaagcggc attcggtcat ggattggtgc gactgtgcgg ttaggttcag tagtcattat
      961 gattgattct gccatttttt catcctgatg gctacgataa aaaccgccaa tatacactat
     1021 tttttcctta tttgaaaaca taaatttgtc tttttcttca ttccactcat tgggaaaaca
     1081 caacgatttt gcaaaaatgg ttgatgaaag gtcttttttt cttctactgt ctctgcacgg
     1141 gcattaatca tcaattgtcc ttttttaaat ccggtaaatc cccacttcat gatttccgga
     1201 gtgaggatgt tttcttcctc ttttcttaac gtcacaacaa gatttgacgg aaaaacttct
     1261 ccagctgcta attctgctgc ctgcttcggt tgtttcgtct gggcttctcg ataataattc
     1321 tgaaggagct ctgactctag atcaaaaaaa taacgaccac acatcctaat ccctcccaat
     1381 ctttttttct atcatacact gcaacaagaa gttcgcacca acaaaacgct ttcaattttt
     1441 gtagaactaa aaaagttgtg acaagtgaca aactctccag tgaatggtat tctcctgcca
     1501 actcctcggt cacaagtcac aatattcaac aaacatgaga agctgctttt tgaaattgtt
     1561 ccttgtgact cggagtgaaa cggcaggctt acgacctctg ggtaaacggt gttcaaaagc
     1621 cagtttctcg gtattaagcc aaatttatgc aaaaatgtag aaagctattt tcacaaaatt
     1681 tttcttaata ctcgaaacta agcgactttt tcacaacctc ttccttaaac ggtgttcaaa
     1741 agcttgcatc tgcggtaata agcccaacca aacgaaaaat atgagcagct atttttattt
     1801 ggctgttctt attacttgat gcagggcagc tttttcacaa cctctccact aaacggtgtt
     1861 caatcagcta accttcggta ttagctcaaa aaacggcaaa atatgaggaa ctattttgcc
     1921 gtttgtttct ctaatactca ggtcaaagcg ctgatttcac aacctctaat acacggtgtt
     1981 ccagaagtag cttcttcgaa aaataagccg aaatttcaca aaaatttgag aagcaatttt
     2041 cgtaaattcc ttcttatttc ttgaagctga ccacttctgt cacaacctct aattattaaa
     2101 gaaccttttg cgaagttaac aatctttctt tgatcaattg aaaattctgc ctaagtagtg
     2161 atagatcctg tgtgactttc aacaataaga tacttccctg gatttcagca atcaacgctt
     2221 tggcttgacg gtctgcttct tcatcggaca gtttttcttc agaaagtgcc aggatatttt
     2281 gtttcgtata cttgacccat tgattgacta attctagtag caacagacgg tattcttcat
     2341 ccactgtact caactcaata atcaaattac ctacaggaca gccatgataa gtgatctgtg
     2401 tctcatgatc agcgaaaatc cagtccaaca tttcttctaa tgcttcttct ggctgttttc
     2461 cagcatttaa gatgtcttcg aacaattctg tctgccatac gtccatatgc gcatggatca
     2521 ccgctagaca aacttctttt tttgaagaaa agtaataata aaattgacct tttcctgtat
     2581 cagaagctgc tagaatatct cggattgacg tttcatgata gcctttttta taaataagat
     2641 ctttggtcgc ttccaagatc ttttcctttg ttttcaatga tattctcctt tttcatttct
     2701 catagtccta tattatacag taaattcatc attttttctt cttaatcgtt taaaaaagac
     2761 tgtgccaaat tatctgacac agccctcact ataaaactgt tctcatatag ctagatgttc
     2821 attgattcaa gaactgcgag gacaaaagca attcctatct tatgatagtt gctctaatac
     2881 ttcctctgtt gtcatcactt gatctgcaat aaagccaaag ttcgtcaacg ctgcatccat
     2941 tgcttcttgg ccaggagcac caattgcatc tgtcgctacc acaacattga atccactctc
     3001 taccaattca cgcatatggg aatcgctaca caagtttccg ttcattccac caagaattac
     3061 tgtgtcgatt ccattttttc tcaattggag cgccaaatca ttgctttctg gtccaaagat
     3121 tttatgagga gagctgatga tcgtattttc atccaaataa ggtttcaatt cttcgataaa
     3181 atcggctcct gaaccttctt ccactgattc atattgactt tttctagcaa acatctgctg
     3241 ctcaagcatc atatgttctc ctgcaccgcc aaattgccat ttatggtcat gtgggtaaaa
     3301 ataatgagga gaaataaaga gtttgtatcc tttttctttt gcttgtttta ccatttcaat
     3361 catattttcg atcgtattgt atttttctaa gatatctttt gtcaaaccaa agccaccgcc
     3421 tgctggtttc aagaactcga cttgcgggtc agtgagaact actgctgtat ttttattatt
     3481 gaacatggtg gattctccat tcgttattta ttttaataca tcatttagag cttcactcat
     3541 tgtcggatga gaatagattt gatctctcaa taacgtataa ggaagttttc cattcatagc
     3601 tagcgaaatc aagttgatga cttcatgaga atcttccgca tagatacttg cccctagaat
     3661 caagtcagtt tcagggtcga ctaaaacttt gaatacacct ttaggatctt ctaatacttg
     3721 tgctttaggg acaccgcttg tcatatactt gaataatttg taattgacgc cttgtgcttt
     3781 ggcttgtttt tctgttaaac ctacattgga taaagtcgga gtgataaata cactgtaagg
     3841 cacagctttc cggttattcg ttgttcgttt attctcgccc ttcaactgat ccataatgat
     3901 tcgataatca tctagagaga tataagtgaa ctgcaatccg cctttgacgt ctccaatcgc
     3961 ccaaatgttg tctgcatctg tacgaaggta ttcatccaca gcgattgctc cgcgatctgt
     4021 tagtttaaca tctgtatttt ctaatccaag tgatgctgta cttggttttc ttccagttgc
     4081 agccaaaact tttgacgctt ggattgttac ttcttggcca tcttctgtaa aggtgacggc
     4141 agctgttgat tcttggtctg ctacttgatc tacagataca cctagatgga attcgattcc
     4201 cgcatttgtc atgtcttcta aaatcatttg cgcgatatct tcatcttcac gtggaagaaa
     4261 ttcagaatgg gcatcaagaa cgacaacttt agatccgtat tcattgaaca ttgatgcaaa
     4321 ttccaagcca atatatccag ccccgatgat cactaatttt tccggtaatt gttcctgatc
     4381 catcgcttgc gtagaatcaa tcaagtagcg acttgtattc aatcctttga ttggtaaaat
     4441 gattggttca gaaccagtat tgatgaaaat ccgttcgcct tcaacaatca ctttttcacc
     4501 attattcgtc acttcgattt gatggttaga aagaaaacgt gctgtaccgt ccatcactgt
     4561 cccagttgcc tcatcgctga tcatatgata atttttggcg cgaagcatgc ccgtcaattt
     4621 ttctttccga gcaacagcct ctgtaaagtc gattcctctt tctccattga aaatcaatga
     4681 tttagaagga atacagccga tgttgataca tgttccgcca tacatacgtg ttgacttttc
     4741 aacgactaaa accgattcac cttttgaagc taacgccttc gctaaagtct taccgccctt
     4801 tccaaaaccg atcacaatat tttgatattt ttccatcatt tttccctcgc ttctttttta
     4861 cctaccgatt ggtacaaaaa tatgataacc gataattgtc tattctccaa atcatctgct
     4921 ttatttgtca aaaaaaacca gacaaaaagc ggtcctttca cgtttttagt ctggttcgat
     4981 ttcctttatt cttctaaaca atcgttactt ctacatcgat atttcctcta gttgctttgg
     5041 agtaagggca gaattcatgc gcatcttctg caattttttg ggcttcttct tcgctgatgc
     5101 catcgatatg cacttctaat actacaccga tctgatagcc gccatcatct aaattataaa
     5161 gagagacacg tgcttttact gtggactctg ctgtcattcc tgcttctttg atcatatgtt
     5221 gtaccgcccc attgaaacaa gaagcataac ctgctgcaaa taattgttct ggatttgttc
     5281 cttctgcatg gattcctgga ggagtgattt tcatatgcat cgagccattt ggtgcctcga
     5341 cttctccatt gcgcccgcca tggttgatca ttgctgtttc gtatgctttt ttcattgtac
     5401 tgctcctttc gattgaccat ttgctacttg gctataatta tagtgtatga caagtaaggc
     5461 gctttctaca aaaattctgc ttattcgaat accagaatgc cgtcttctac tatttttcca
     5521 aaaaacaaaa aaatactact cgtgaacaac agcgtcatat ttgttccaaa ataaatagca
     5581 atcttttcta cataatcttt tatatgattg attttaagat acatatatac cagaaagttg
     5641 accccataaa ccaatactgt taaaaaaata accatattcg ttaccatttt ttcctccttt
     5701 tgctggtctc cctaccagca ctcgatttaa ccataccact ttttttgccg tccaagcaac
     5761 tagcctttca aaaagactgg tttattctgc tgttaatgat tcaagatcag aaaaatgtcc
     5821 gaataatttt gctaatttta ctaacgccaa cttgttcttt ccgaattcat cattttctat
     5881 ctgtaatact agtaacggct catgtaagct taaacggatc aaaaaccagc cgtttccgta
     5941 tggctcttct agatcatatc gaataccttc ttcattttcc gggtcgaagt tcatcccttt
     6001 ttcttcttcc aacagtcgct tcatttcttc taatatcttg tttccttgtt cgcgtggttc
     6061 atcgctgaac aattttaatc ggatttcttg tacttctacg ggctgtttca actctttgat
     6121 ttgttcatct aatgtgatac cttttctttt taattctggc aaaagcatca ggatctttgc
     6181 gatgacatat gcaccatcat ccagaaaata gttttccttg aatgcagcgt gtccgcttgt
     6241 ttcgatggct agctgtgtat ctttcccaag acggttaagt tctaatgctt tattgattac
     6301 atttcgatag ccggaaatat aacgaacttg gatgcctcct ttttcttcaa tgaatctttg
     6361 tagatgagaa gaagtagggg aattcgtcac gattcttgtt cctggatgct cttttaatac
     6421 gattgtactt aatactgcga tcaaattatt tcgattgatc actgttccag aagcactgac
     6481 aactgcagaa cgatccacat ctgtatcgaa aatgatccca agatctgctt catttgctaa
     6541 aacagcctgc ttgatacttt ccatcgcttc tttattatca ggatttggga tatgattagg
     6601 aaatcggcca tctggttcca aaaattggga acctgttgaa tccgcaccta agctattcaa
     6661 tactttttca gcaaagaatc caccagcacc atttccggca tcaacaatga ttttccaacc
     6721 atttagtggt ttgctttcta gtgttccaat ccccttttta atttttgtga ctaaatcttg
     6781 cgcataaggt gtcaaaaggt ctgctttttc tacgcttcca gtttgttcgc tttttatttt
     6841 ttgctgctgt gataggataa aagcaatatc ttctttttct gctcctcctt ctgaggtaaa
     6901 gaattttatt ccattataat aatagggaag atggctagca gtcagcataa ccgcagcatc
     6961 gcacgagaac tgttcaaatt gagtggacat aaacatagca ggcgtagtag ctaattcgaa
     7021 atcgatgaca tgtatccctt gttctttcag actttggatc aacgcctctt tcagtgctgg
     7081 tccgcttatc ctactgtcat gaccaatccc aatcgtccat tttttatttg gatcggttga
     7141 tttcttcttt ttctttatcc agtttgctag tccccagccg atctttttta ccatgtctgt
     7201 cgtcaagttt acttcatatc cttcaactgg taatgcgatt cctcgaatat ccgatccatt
     7261 ttgcagcgct ttcatatctt tcatataaaa gtcctcctca tttattccct cattttttcc
     7321 agcttttctg caaatcgctg tgcttcttct tctgagcggc aaataataat gaatgtatct
     7381 acaccggcca tcgttccgac aacttcaggg taagccactt catctagcca attcgttacc
     7441 acatcggcac catttcgttc agtcaatacg ataaccatga actgaacaga ctggatacgc
     7501 aaaacctcgc gtctaattgc tgtacgcaaa cgttcttcat ttaaagaaac agatggctgg
     7561 ttaaataatg tatagcgtac tattttgttt tcattttgac tttttactaa cttcatttct
     7621 cgaatgtctc gagaaatcgt tgcttgagtc acatcggcgc ctgcttcatg cagccgcgca
     7681 agcagctctt cctgtgtccc aataggttgt tctgtaatga tctggcggat cagtgcttgt
     7741 cgctgtttct ttttcatatt agacacctct caatgttgat tatagcaaaa gataagtaat
     7801 atttcttcat attttggtat tttttacttt tattttttgt tttcattcag gttgctaacc
     7861 tttttctatt ttaacacgca aaatcgtctt cattttttca ggtgctgatt ttcttggatc
     7921 gctgatgtaa atctctttgt gttctttaga agctctttca tagccttctt ttgcgatgaa
     7981 tgcttctaat ttctcaaacg ttgctggttc ttcggcatag ggcccgacgt gtaagatttg
     8041 ggcacaaaga ccttcttcca tctttttgaa tactacttgt tctttcaagt cttccggaag
     8101 tttgctagaa cgctgaatgg cttcttgtgc tatcgcttct gtaacaaagt caggctgtcg
     8161 gatcatcaat tgataagaaa aatgttcttt tttcatcact ggttcatgca aatacttttc
     8221 ttgcagtccc cattgtcctt ccagtggata gacagtatac atctgataat caggaatcag
     8281 ccaatttttt ttaggcgaca tgcgtattgc atagctgact gcatatagac aggctactct
     8341 tcgtttaaag tcttcctgat tcgggtcgcc gatccctctg atgctaaaga atgatttttt
     8401 aggaacctct agtatttgcg ggcttttttt catactatag ctcttgtctt tacgccattc
     8461 aattttttcc atttttcttc ctccgcgaaa ttccatttag ttatttatta tcatacctct
     8521 ttttgagtga cttggctaat cgtgttgaca ctatttttca gtttgtgcta gaataagtga
     8581 agtaaataaa tcgtacagat aacacgtttc ggcgtgtcga gagagaggcg gtttctattt
     8641 ttataataga aatcactctc tttttttacg aaatttttta gaggtgatgt aaatgacaaa
     8701 acaaaaacag ctgcttttag tacctgcagt aattgcaaca gggatgatgt cttttgcggg
     8761 cgtattgatc gagacggcca tgaatgtaac tttcccaact cttatcagac agtttgattt
     8821 aacgactgca caagtccaat gggtaacaac gatttatctt ttgatgattt cgatcattgt
     8881 tccgctgtct acttatttga atcgcaattt tagtctcaaa aaactctttt tagcttcaaa
     8941 tctgcttttc ttggcaggta taatgatcga tttcttctct cctaccttca tggtcctatt
     9001 gtttggtcga ttgctccaag gtgcagcgac aggtatcgct cttccgttga tgttccatat
     9061 tatcttgaca tttgcccccc tcaatcgacg aggcgcgatg atgggtgtcg gtactttgac
     9121 aacggccatt gctccagcaa ttggccccac ttatggaggc attatgactt cacattttac
     9181 atggaatcat atcttcctgt ttcttgtgcc cgttttgatt ctttctttga ttatcggctg
     9241 gtttgctatt cccgagatgg cagtacaaaa aagtggttat ttggattgga taagcgtttt
     9301 aggaatttgt cttttgttta gtggaagtct aacatttttg agtacgttgg gaacagtttc
     9361 cagctggatt gctttaatca tcggcggtat tggctggttc cttttttact atcgaagtaa
     9421 aaaagtggag catccactga tccgactgtc tattctttca aataaaacat tccgcttgtt
     9481 tttgattggc ttcttagttt atcagttttt attacttggt gtatcttttg tcttgccgaa
     9541 tttccttcag atcgttcaag gaagtagtcc ttttgtcgct ggattagcga tgcttcccgg
     9601 cgcagcggtt ggtgctttgc tttctccttt ttccgggaaa atgctggatc aatatggtcc
     9661 gaagaagcca atttttgctg ggctgattct ttctttgatt ggttggctag cattattcct
     9721 actcatagga cacgcttcag tgggtgtatt gattgcttgt catgtgtttt atatgatcgg
     9781 tatcggatta tcttacagca atatgatgac caccggaatg aatgcactga atgaagaact
     9841 acaaggagac gggaacgcaa tgttcaatac cttgcagcag ttttctggcg ctgtggctac
     9901 ttcattagta gcggtcatta tcaattacgt ccagcatcat acttcccata actatgaagt
     9961 gtctactaca ttaggatcaa aagcagcatt aggcgtcttg ttgctgttgc ttctcgtaag
    10021 ctttgctcga ttcgcctatt atctgttctt tgctaaaaaa gcgtagattc catatacggc
    10081 aggtgttgca tctgccgttt ttttgtgtga aaatggttgt ttgtaaaagg aggctttttt
    10141 atggaaaaaa ttgccattat cggtggcggg atcattggta tgaccctagc cagttactta
    10201 gatacatcaa aattcaatgt tgctttattt gatgaaggga caggacaggc aactaaagct
    10261 agcgctggga ttatctcccc ttggttgtcg aaacgcagaa acaaacaatg gtatcgtctg
    10321 gctaaagacg gcgctgcttt tttccctaaa cttataaaag atttccaact tgatcaaacg
    10381 atttacgcac aatcagggac acttttgctt cgacctgaaa aagatttagc tgaattggct
    10441 gttcttgccg agaaacgaaa agaagaagcg ccagaaattg gaaacatcga atggctttca
    10501 cctgaacaga catctcaagc acttccgtta ttgaaaccag cagtttcact gcgtatcagt
    10561 ggtggtggtc gtctggatgg aaaagcatat ttagaacatc ttggtcagcg tttagcacaa
    10621 aaacaaatgg agcagatcca ggcaaaagtc actttgcata agaagagcga ttcttggctc
    10681 atcaagggac cgtttggaga atacacagct gatcgtgtaa ttttgacacc tggcccggca
    10741 cttaagcctt tattacaaga attaggctat gctgcagata tacgtccgca aaaagggcag
    10801 ctcttagcat ttcagacatc ttataagatg agtcaagact ggcctgttgc tatgcttgac
    10861 ggagaagctg atttcattcc tttcatggat ggaaagatcc ttttaggtgc tacccatgaa
    10921 aacgatcaag gctgggattt ggctcctact agcgaagctt ataagggatt gactaagagt
    10981 acagaacagt tcttgactga tccagatcag ataaaaaact ggccatacga gttccgtgta
    11041 ggtacccgtg cttatacgtc agatttttcc ccatttttcg gcgtactgcc agatgatcca
    11101 agcttactgg ctgctagcgg tctaggctct tctggcttga ccacaggtcc ttatatcggc
    11161 tatctattag ccaacttctt aaatactggt cattggccta cggaagatta tcaaaaggac
    11221 atctccacct atattacgaa aaatccatca tagaaaaaca gctttttcaa gtaaggatcc
    11281 cgagcgatat tgcgcatgga ttacttcttg aaaaagctgt tattttagtt caatttctga
    11341 atcaaattct ccaaactttc ttttgcttca tctggcaaga gatcttttcc tatctgagct
    11401 tcaatgaatc gtaaacgaat atcaagtcgt tgtttcacca gatttttata ggacgtatcc
    11461 tcaaaagaaa caggaaaatc tggtataggt aaatagtgga tgtcttcaaa tggaccaaac
    11521 gacttgaatt ctgccgtttg ttgcacgatt ctttcaacga ttgacaatgt cgtttcaggt
    11581 ttgatttttt tatcatcgaa atatccagta ttcaggacat agcaggctgt ttgctgtttc
    11641 aaaaacaact ctcgaaaagc ttgatagtct tccctaagag gatagacacg gaaaggatta
    11701 gcaaatggtt caatgactag ctcatctagc tgtctttttg tagtgatatt ttccgcgtct
    11761 gatcgttttg ttgctaatgt tgcaccaaaa gacgctgcta aaactgggtc attgatcttg
    11821 ataattggcg gaagcgaatc atctttcatg atccaaaaaa cagcatcgat cttttcgcta
    11881 agatgatcga ctcggtcggg tgtcgcataa cgtgatttga ctgtccgccc atttccgttt
    11941 cgtatatctc ctgttactag gactttttct cctttacttg tacatgtcac gcccacattc
    12001 tgacaagtaa ggaaagaaga aatggccgga tcatcagacg gatagtcttg tgttttatca
    12061 aagtaagaag gttccaaggc agtagcaaaa ccattttttc gagaaataac gaaagcatcg
    12121 tcatgcaaga tcgaaacaga gtgaccttcc gtatgttttg ctaaggtaat cgttgatttt
    12181 ccagaaccgg acaacccaaa tacagccatc gtataggtct ggtcattact agcatattgt
    12241 ttcatcccac cgtggcaggc aataaagcca ttgcgatttc ccaatgccca agcaagcgtc
    12301 aaagtcgctt tttttaattc tccaaagtaa cgtaatccta gcacagccgc tgtattatgg
    12361 agagcatcaa acaaaatgag tccatttgga aatgtttcat gtgtccattc gggatcacaa
    12421 aagatataaa gatctccctc atcaaaggaa acagactttt gataagtctc taagatcttc
    12481 gaattcgctg gctgaaaatt cagcaaataa gaatacaaat tgttctcaaa tccttctgga
    12541 atcagcaaat gactttgcac agaaaattct tcagataggc caacgattac ttttgtatgg
    12601 taaaactggc gcttgcgact ttgatacaca gcttctctta aaattttctc gtatttgctt
    12661 tgttccttgt ctaagtcctc aaagatccgc cgagcacttg ctgttcttcc cacaatgctt
    12721 ccatcattga atactagtgt cctaacatca gctggtaaat ctagttcttc agcatgtgag
    12781 attgttaaat ctgtgatgat cgttcctgga ctcccttttg ctagttgata agctgtcttc
    12841 ctatcaaaaa cttcatgaac attattaccg taaaatgtcg tttctacaat cgatcgaata
    12901 ctggataaca gtggatttcc acttgtgatt tcgtttaatt cgagactctc ttttgtactc
    12961 atggctcctc ctcattccct aaacaaaaaa acgttttctt tattatacat tattcgagtt
    13021 tttatttgta ctgctgcgct gtgggaagca aacgagttat ttttcacaca aaaaaaccga
    13081 gaacttgaat aaacaagttt ctcggtttca tcattttcct tttatcggct tagtaccagc
    13141 cgtttgctaa ccagaatgtt ttagcagcat cccatgaacc ataacgagat gttacatatt
    13201 gttctgctac acgttcttga ttggcagctg aatagtcgcc gtttaagtat gaagcatcta
    13261 attgataacg gccgatgtaa cgtccgttag tagctgtgta tgaaccgcct gattcttttt
    13321 gtgcgatcca ttcttttgca gagcttgaag ttggcgctgt tgcagcagct ggggcagcag
    13381 gagctacttc aactgtttca acaggtgcaa cgtatgtatg ttcttgcgtt gctgtttcag
    13441 ttgtagatgc tgtattttct gttgttttgt tttctgttgt tgctgaagaa tcatttgaag
    13501 ttgggattgt taattgttca ccaacataaa tgcggttgat gtttgcgatc gaattttttt
    13561 cagcaattgc atcgatcatt gagttgtctc ctgcaaattt ttgtgagatc ttagataatg
    13621 aatcacctga ttttactgta taaacttcat cagcgtgagc atttgtagtt cctacaaaca
    13681 ttgcagtagc accagcagca aaagttgtac ctaaaacaat tttcttaaat gaattcatat
    13741 taaactcctt tttttctccg ttttttattc tttcgacgct attaacttta tcatttagaa
    13801 atatttcata ggtaaaagaa acatgacatt taatgacaaa ataacgaatt atttaatatt
    13861 tgtaacattt aaacaaatat ttttttgata caaaaccata aaagccttgt tgtataagca
    13921 aagtaatcgt ttttctatgt ttttttattt ttgaatgaaa aacgcagatt ctgtaacatt
    13981 cactgcaata atccataaaa aaaagcaaaa aaatttttga tttttatcaa attctcttaa
    14041 aaaaatgtaa aaaatacaaa aaaaccagta attgttacaa caattactgg acaaaaactt
    14101 tgaataatgt taactatttt tttattttaa ctttctccgc aataatttct gggcatgttc
    14161 caattcgttt ataacgactt cttctgtttc tttagctaat atttcatcta atacatcaag
    14221 ccatttttcc ggttcttttg ttcctagacg tccaatagcc caagctgctg ttcctctgat
    14281 gacagggcgg acatctgtta aacattctga aatctcaggc aatgccgttc gatcacctag
    14341 attagctaaa gcaatcaatg cgtttctctg caaaggtttc ttcccacgcc atgaaccagc
    14401 taaatgccca aattgctgtt tgaagtcttt attagacatc gaaagcattg gctttaattt
    14461 tggatatatt tcgtctactt ttggttccat ctcttcatga aaatgaaaat cttttccttg
    14521 attgtaaggg cagactaact ggcagatatc acatccataa atgacatttc gcattttttt
    14581 acgatattct tccggcatca tcccttttgt ctgagtttga taagacaaac atcgctgggc
    14641 attcattctt ccgtcaccaa gcaatgcttt tgtcggacaa gcagtcacgc agcgcataca
    14701 gtcaccgcaa ccaaattctc ctggtttatc aggctcaaat acaatattag taacgatctc
    14761 accaagatag acaaatgaac cgaactcttc agtgatcaac aatccgtttc gtccaataaa
    14821 tcctaaacca gctcgctgtg ctacagcgac atcgatcagt tctccagtat ctacttgcgg
    14881 agctagacgc cattcctctt ctttttgcca tttttctgct cttgtttgga tgaattcgat
    14941 caatcggttc aaacggtctc tgagtatatc atggtaatcg atcccccaag aagcacgagc
    15001 aaactgcccg cgtttttcat ccctaggcac ttcttcatgg atcctagtag gatacgcaag
    15061 tgcaatggaa atgatcgatt tcggctgatc aaatgtcatt tctggataaa gacgctcatc
    15121 gatatttgga tgttcaaagc cagaagtatg gccagctgct ttttgttctt ccaacgattc
    15181 ttttaatgaa tcaaaaggtt ccgccgtggt gaacccgatt ttgtcaattc ctaatcgttt
    15241 gctttcttgt atgatttctt cttttaatgt catggtcttc ctcgcttgct gttaacggct
    15301 gtataaccca taatatagtt tttctttttt cagctggaca aactggatct gctgatcggc
    15361 aatcttcttt tcttccatcc atttttttct tgcagcaaat acttcccaat aatttgttga
    15421 aattaatttt cttttgttat ctaatgcatt aaaaaaattc aatgaaactg gttttgtact
    15481 taacagttca tggagcctta cctcttccca tggcgaaaac tcagacagat cgcgggaata
    15541 caatacttct tcatagagat ttttttgctg tgtgtacgtg aatgtttgcg ggattttccc
    15601 aggcctagca atttctacta gacgattata aaacatattc attaatttgc tgttggcaat
    15661 aaattgactt ttataatagg ccgactggat ctttttgatt actccttctg ctttgatgac
    15721 tgaaaataat gcaggccatg ctttgacggt tatttcgtcg ttttgtttaa ctaatacgcc
    15781 aggtgtgaag ccgactggag aaaggaacac aaaataaccg ataccggtat tttcatctaa
    15841 aggctgaaat tcatcaaaca accatttgcc tatgtacagc tcttcatctg gttctgttgt
    15901 ctcattttga tttgctatga ataatttagc taattctgct tcaagaaatt gaaggtcttg
    15961 atccttgtcg gtattttcct gctggctgat caatcgaaag acttcttctt taatcgtata
    16021 tttatcttta cgtgtaaaat tcatagccac accttccttc cttactctaa ctataacgga
    16081 atttcttcaa aaaaggtatc tgtacgacga aaaacagcat aatttttttt catatctctt
    16141 ataaaaaatg caaggtctgc tcctcaagct agaccttgca cttttcagct ttcttttgtt
    16201 tgtgacaaac cttcatggat cgtttcaata ttccatttca tcatctgata gtaagaatct
    16261 ccttgttctc cttcttttgc tatggaatca gtgaacagtt tatcatagat tttcaaaccc
    16321 gtttcttttg ctacccgttc catgcttctt gagtctacac tggtttccac gaataaaacc
    16381 ggtacttctt ttgctcttat ctgatcaatg atcgctttca tttgatcagg cgtaccttga
    16441 ctttctgtat tgatctccca tatataagct gctggcaaat catatgctcg tgaaaaatac
    16501 ttgaatgccc cttcacttgt tactaataat tttttgttct cttcgataga agcaaaactt
    16561 tccttcgctt gtgtatctaa ttcttttagt ttttccacat atgcttctgc atttttttta
    16621 tagagtgtcg cattttctgc atctttttca gagaatatac gtgcgatttc ctccacatat
    16681 tttattccgt tagataggtc tagccaagca tggggatctg cttttgtatg ttcttcaccg
    16741 ctagttaaat aaagaggttc tacatttttg ctaactgcaa aataatcttt tccttcttct
    16801 tttttagccg tttccatcaa gttatcgaac cagctgttac ctgtttcaag attcaaaccg
    16861 ttgtataaaa taacatctgc atcgcttgcc tttttgatgt cttctggtag tacttcatat
    16921 tcatgcggat ctgttccgac tggtacgata ctgtggatat ctatttgatc tgttccgacc
    16981 tcttttgcca tgtccgccaa gatcgaattg gtagccacga ctgacaactt ttctttactt
    17041 ccttcatccg cttggtcaga agcctgcttt ccgcaaccgg ctaataccaa gaaactaact
    17101 gccaagatta aaaagagtga tttttttgtt ttcatctatc tgcttccttt ctgaaataaa
    17161 attccttttg ttggagaaaa taaaaaagca aggataaaaa atgcggtaca tgctaacacg
    17221 atcgtagctc ctgatggcca attgtaacta taactgaaaa acacaccgac aactgcactt
    17281 agcataccga ttcctgcagc tgtaatgatc attttcagta aatggttcgt tagcaagtaa
    17341 gccgtggcgg ctggtgtgat caacatggca atcaccaaga ttgttcctac tgtctgtaaa
    17401 ctgactacag ccactaatgt caaaaagaac atcaaaagat aatggatcag cgatgtgttc
    17461 agcccataag cttttgccat tgtcggatcg aatgatgtga tcttcaattc tttataaaag
    17521 aaaaagacaa atatcaagac gattccacta acgagtgctg tcagcaacaa atcgctttcc
    17581 ctaacagcta agacattccc aaataaaata tgatacaaat ctgtcgcact ctgggcatat
    17641 gaaatcaaga taatccctaa tgcaaaaaag gagctaaaga caattccaat cgctgtatca
    17701 tttttcaatc ggctccgctg agtcacgaaa ccaatcactg ctgctgttag catcccaaaa
    17761 gcagtggctc caaagatgta actaaaacca aacatataag aaatggctac acctggaaga
    17821 actgcgtgag agatagcgtc tcccatcaaa gacatccctc gtaaaataat aaaagaaccg
    17881 atgactccag aagcaagtcc tacaagcatg gaagtgacca aagcgtattg caggaattga
    17941 taattcatta atccatcaat aaaggattgg atcatttttt ctctcctcct tttactaaat
    18001 gtctgatgat ctcaccatag gccaattgaa ggttcttcga tgtaaagact tcttgtactg
    18061 gaccggaagc gatcagctgt ttatttaaaa gaataacctc atcgaaatat tcttctactt
    18121 tatgaagatc atgatggacg atcaaaatcg tttttcctga attcttcaat tcctgcaaga
    18181 tgtcaaagat ctttcgttca cttaacgcat caatccctac gaatggttca tctaaaaaga
    18241 tccattctgc tccttgggct agagctcttg caataaaaac tctctgaagc tgtccacccg
    18301 atagttcgct gatctgtctt ttggcatatt cttccatccc tacttttttc aaagcttgtc
    18361 ttgcacgttc tttttctttt ttcccaggtc tttgtccaat tcgtaaagat ggatatgttc
    18421 ctaaaagtac aacgcctaat acatcaattg gaaaggaaag atccaattca cttcgctgtt
    18481 ccacgtaggc tattttttta cggactgagt ttaccggctg tccagaaaag gtgactttac
    18541 cagtagtagc tggtatcaac tctagcaaag atttcataaa tgttgatttt cctgcaccgt
    18601 ttggtccgat aataccggta attttttgtg gatttatcgt caagttgata gttttcaaaa
    18661 cagttttccc ttgataagcg gctgaaaggt cttgaattac aatggccgta cgttccaaat
    18721 cttacactcc tttttaggtt tacctaactt tttatttaaa tatagtttaa ctaaaatgga
    18781 aagcattttc aagtagaatg atgaaaaagt ttttttcgaa ttttcctcgc attttatgaa
    18841 aattttctgt agaatcacat caagagttca ataaggctaa cctaataatg aaaaacatgt
    18901 gttgaaacgt ttgattattt tttcttgttg actcaacaac gaaaggagtt tttgtatgga
    18961 agaagaaaag ttaactcgaa gtcttagtgc ccgtcatatc caaatgatcg cactaggtgg
    19021 aacgatcggt gtcggtctgt ttatgggtgc ctcctcaacc atacgttgga cagggccctc
    19081 agtgatggga gcctatgcga ttgcaggatt ctttttgtat ttgattatgc gtgctttagg
    19141 cgaaatgctt tacgttgatc cttcgactgg ttcttttgca aattacgcga gcgagtacat
    19201 ccatcctgtg gctggctact tgaccgcttg gagtaatatt tttcaatata ttgtcgtagg
    19261 aataagtgaa gtgattgctg taggatctta tatgaattat tggtggcctg atttgccggc
    19321 aattattccc ggaatcattg tcgtcttgtt tcttatgctg gcaaatctta tttctgtcaa
    19381 ggcgtttggc gaattagaat tttggttttc gatcatcaaa gtcataacga tcattttgat
    19441 gatcattgca ggtcttgggg taatcttatt tggatttggt aatcatggtc aggcagtagg
    19501 gatttcaaat ctttggaaaa atggtggatt cttcactgga ggcgtcaaag gatttttctt
    19561 tgcattatcg atcgttgttg cttcctatca aggaatcgaa ctgatcggaa tgactgctgg
    19621 tgaagcagag aatcctaaaa agacgatcat tgaagctgtc cagtccacta tcggtcgaat
    19681 cttgattttt tatattggtg ctatttttat cattgtgagt atctatccgt ggaatcaatt
    19741 gagtgagatt ggttcacctt ttgtacaaac tttttctaaa gtcggcatta catttgctgc
    19801 aggactgatt aattttgtcg tgattacagc ggcattatca ggttgcaatt cagggatttt
    19861 cagcgcaagt cgtatggtct atacacttgc cataaatgga aagatgtcta aaaaatttct
    19921 gaaactatct cgtcacggtg cgccttttta tcctgtcgta gcaatctcag gtggaatctt
    19981 aattggtctg atcttaaatt atcttctacc aatgttcatc aaccagtcag aaaatatttt
    20041 cgttttcgta tacagctcaa gtattttgcc tggtatggtt ccttgggtag tgattttgat
    20101 cagcgagatt cgcttcaaaa agaagcacgc agataaaatg catgatcatc cttttaaaat
    20161 gccactatct ccttatacga attatgtgac acttgctttt ttagctatcg tattgatttt
    20221 catgtttatc aatcctgaaa cgagaatctc attgattatt ggactcgttt tcttgcttta
    20281 catgacgatc cattactttg tacgcgaaaa aagaaccgga aaataaaaaa agaacgaagc
    20341 ttcaccttag tggaagcttc gttctttttt attgctttta tcaattcaat tttagcgtct
    20401 caccgggagt caggaaataa ttctccatgc tcatcccatt cagcgacaag atcgtttcta
    20461 ctggtacgcc agttcgttcg gctatttgat ttggaccttc tccttccaaa actacggttg
    20521 tcgcagcctg tgaagtcgcg ctgttggtat tagtttcaga ggaatctgtt gtgtcttgtg
    20581 ttgttcgagc ttgcatttca gaagcttcta ccgactctgc tgtctcagaa tcagaagatg
    20641 ttgtgtcttg tgtgcttgtt gactctgctt gaagagaggc gctagtctgc aaataaatat
    20701 cggaaatctt agcgacatga ttcgtataat tagccgataa ttgattgatc aaagtatcta
    20761 agtctacacc gtctttattt tctgctgcct gatacgctgc acgtaatttt ctgatccctt
    20821 cgtcggagat tgcttgaagc tcacgtgctt tttggttagc aactgctgat aaaccagcta
    20881 ttccctcttg atttccctga atttctgtct ggtattcttc aatcaatgca ggcgtctttt
    20941 cttcgatctt tttcgaataa tcatttacga ttgcttgaag ttgctctggc aaaccatttg
    21001 ctgttttttc ttcagaagtt tgtgtctctt ttgttttagt tgatgactca cttgtttgtt
    21061 tcgtctctgt tttctttgtc gttgtttccg ttatggtcgt acttttcgct tctgacgaat
    21121 tttttccatg aaaatataga cccgcaactc ctcctgctat gatcaaaaac acggcaactg
    21181 ctgccccaat catgatcatc cgcttacgag ctgcctgttt ttgctgtctt cttcgggtca
    21241 tccgaacatt ttctccccac tcattttcat catacatttt tttcaccacc aatttttatg
    21301 tataatagcg ttatcaaacg cttcatattc ttattgtagc aaataattgt cgctgtgcac
    21361 atttttatct ttgttattta taagaaaatt tcaccagttg agatgattcc aagattgtcc
    21421 gtcgatttct ccttgcagct gcattgttcg ttcgtctatc tcagccatca gtttctttat
    21481 ttcatataag agcgcacggt cttgatattc tgatttttcg cttaattcat ctaattgttg
    21541 gatcagccaa tcatttgtca taatgaagtt cctttcattt cttgcagtgt aaaggtcaag
    21601 tcttcgatct gctcttttgc ctcagtcagt gcttctacga tatatgcttg tttttcagat
    21661 tcttcttcct gcattttctg attttcctgt actctttgaa taaaccagtc aatccgctga
    21721 gtcagcgatg gtttgccttc caatgagaga tactgctgat aagcaattag cttctcccaa
    21781 cgtttttcct gggataaata cataaattgt gctaaaacga atggcggaag ataggtcata
    21841 tggaatttat ttgcgattcg ctgatacggc ctcaaaaatt cggaaatcgt atattcttct
    21901 tttcctccag cttggtattc tttttccgcc acacctgttg tcaatacgat tcctagttct
    21961 ttccctttta atacatgtgc tgctcgttcc aagacattat cttgccaaat ttttaaatga
    22021 gcaggagaac tataccagta aaacggaaac tggaaaatga tccgatcatg ctgggccaag
    22081 agctgtagtt cagtctctat atctattttt ccgtctggat aacttgattc caaatgatgc
    22141 caagtagctg gtaaaccagc agaagcttct ttgaaaaatt gctgatttaa agattcttcg
    22201 atcgttggat ggctaatgat gataagtgta cgcatccctt ttcctccttt ttagtcttcg
    22261 ctttacagtg tagcataacc gccacaagtt tcttttgccg atgcttgtca ttttaaccag
    22321 actaatcagg ttgtccaaga aactgcggtt tgtttttcca actgtttttt caaggtatcc
    22381 aaagcaatat tcttaaaatt ttcgtttttc atacgtttac gatagttcgt agccgtttct
    22441 ccggtactct ttttgaacat tcggctaaat acgactagac tattgaaccc tacttgatag
    22501 gcaatacttt ccacggattc atccgtcaga gaaagaagaa acgcccctcg attgatccgt
    22561 accccgatca aatattcctt gatactggtg cccatatgat ttttgaatac tcgcgacaaa
    22621 tggctccgat tgaccgctaa atgctgggcg atttcctcaa cagacaattt ttcagcataa
    22681 tgtgcctcga tgtatttgac tgtttcaaca gctaaagagg aatgaacctt ttgtacacct
    22741 ccgctgacct ttccgccatc ttttaaaagg actgataaaa aacggtaggt taatgctgtt
    22801 aactgtaatt cattttccaa ggtttcttcc gtatctttca tgcattctaa aataatgtcg
    22861 atatattttt gtatgtcaga agagaccatc gtgtattggt cttctctgaa aagcgactgc
    22921 cgaatgattt cttctgcagc actcccacca aatgaaagcc agcaatacat ccacggatct
    22981 tctccatctg ataagtaaaa cgtcgagtct cctggacgaa tcaagaacag atcacctttt
    23041 ttcaattgga attgttgatt tttcacatga taagatcctt tgccttccat cacgacatgc
    23101 aggatgtaat cattgcgaat agcaggacca aaagaatgaa acggcatcgt tttagagaaa
    23161 ccacaaaaat caaaatacaa ttctttttct acttgttgat gttccttttt taaaaaaatc
    23221 gattgctcca cgtctatccc tccttactcc tttagtataa tgcaacaaaa agttaaataa
    23281 aagtcacaga aatatattaa aaaggaagcg atttcttgtt aagtttaagt cattaaaaga
    23341 tctttgttat tcgttgtaac cggtttactt agtattatat attgaacagg agaggaatac
    23401 agattatgaa aagcaaaatg atccaacgtg tgtcctacgc tttaggcgct tttggacacg
    23461 acacattcta tgttacatta agcacttatt ttatggtatt cgtgacaagc cagatgttcg
    23521 caggaacaga taaggcaacg aatgcaaaaa tgattgctac agttacaagc ttagttgtag
    23581 gtatccgctt agttgaaatt atttttgatc ctttgattgg tggcatcatc gataatactc
    23641 gtacaaaata cggtaaattc aaaccatggt tagttatcgg cggcgttgtt agttccgtac
    23701 tcttggtagc aatctttacc aatttctttg gcttagctac tcataatacg actttattta
    23761 tcatattatt tgcaatcgtt ttcatcttat tggatagttt ttattcattt aaggatatcg
    23821 ctttttggtc aatgattcca gctttgagta cggaaacaaa ggaacgtgaa aaatttgcta
    23881 cgtttgctcg tttcggctct tctctaggtg caaatggtac tactctagtc gttgtcccta
    23941 tcgttacttt ctttacctat cttgttactc ataaacatat tgaaggcgct tcaggctggt
    24001 tctggttcgg tgtgattgct gctgttattt caggcggtac tgcgattatc actgccttgg
    24061 gcacaaaaga agtcgatact gcgatccgtc agcaaaatga aaaagctggg atcaaagatg
    24121 tgttcaaagc agttgctcaa aatgatcagt tgatgtggct tgcccttgct tatatcgctt
    24181 atgcgattgc caatgcagca acaactgccg tattattcta cttcttcaaa tatgtacttg
    24241 gccaaccaac tgaattttgg atcgttggtc tagttgctgc cttacttggt ttagtagctg
    24301 ttccactatt cccaatgctt acacgcgtca tctctcgtcg ctacgtttac cttggaggga
    24361 tcgcaatgat gatttcttct tactttttct ttacgatcgc aggttcaagt ttgccaatcg
    24421 ttatcatcgg gctagtattg ttctacttcc ctcaacaatt gattttctta tccgctttga
    24481 tgacgatcac agactctgtt gaatatggtc aatggaaaaa tggtatccgt aacgaagctg
    24541 ttactctatc aattcgccct ttactagata aaatcgctgg tgctttgtct aacgggatcg
    24601 tagggtttgt cgctatcgct tctgggatga ctggtaatgc tactgctgct gatatcactg
    24661 ctcatggcgt aacgactttc aaagcttatg cattctatgc tcctgctgct ttgatgattt
    24721 tctccgctat tatttttgct tggaagatta cattgacaga gaaaaaacat gcacaaatcg
    24781 ttgagaaatt ggaaaacaaa ttggctccag ctgatacaat ggaagattaa cttcacgatg
    24841 cagtagttcc ttcccattaa gaaaggatct tgaaaatgaa gattacagaa aaagattttg
    24901 gccaaggtta tcacttgata accttggaga acaaaaacaa gctagcactt tctatctctg
    24961 atttaggtgc tagaatcgtc agtttaaaat caaatgatcg agaattagtt ttgggatttg
    25021 acaccgctga agaatatatc gaaaaagatc cgtatatcgg tgcttctatc ggtcgcaccg
    25081 cagggagaat cgaaaatggc cgcttttctc tcaatggaaa aacttaccaa ttagccacag
    25141 atccaaaaac tggacataat ctgcatggtg gtgctcctgg atttgaatta aaaaaatggt
    25201 cttatgtcat tttgaatggc gaaaatgaag cttctgtcat ttttactact acaagtcccg
    25261 acggagaaca tggttttcca ggtacaatgg atgtggaaat ccgctatact ttgacaaaag
    25321 ataatatctg gcgagtgacc tctcgcggca ccagtgacca agatacttta ttcaatccga
    25381 caaatcatgt ttacttcaac ttgacgggag atgcttctca gtcaatcgat caacatgagc
    25441 tttggctcaa tagcgaagct tatgctcctt tgcgaacaga tagtattcct ataggggtaa
    25501 aagaaaatgc tgcaggaagt gctttcgatt ttcaaatacc taaaaaatta gcgtccgttt
    25561 ttgctagtga tttggatcaa aaaaatcttg ttgacggaat cgatcatcca tttttcttaa
    25621 aagaaaccgg cttgggtaaa gaagccgctc gcttgactag ccccgataaa agaatccaag
    25681 tagatattgc tacagatgct tctagtgtgg ttattttcac tgcaaatttc ggcacagaaa
    25741 caccagaaat gcgcaaccga aaactggcac atcacggtgg catcacattt gagactcaaa
    25801 cagctccagg tgcagagcgc ttctcagcat ttggttcgat tcatttaaaa gccggatcag
    25861 tatttgaaac agtgacagaa ttcaaaatca aaacaagaaa ggaataactc atcatggaaa
    25921 tcaaaagaag cttaaacaca aaatttgccg aaatattcgg acctaaaaaa actacacaat
    25981 acttctcacc aggacgcatc aatttgattg gtgaacacac agattacaat ggaggccatg
    26041 tcttccccgc ttccatcact tatggaacgc aaggtgtagc agcacctcga gacgataata
    26101 aaatattagt ttattccaca aactttgacg atatcggtgt cattagtttt actttagatg
    26161 agctagaata tgataaaaaa gcaaactggg caaattacgt aaaaggaatg gtccttaaat
    26221 taaaagaagc tggacactca atcgatcatg ggtttgagtt attagtggaa ggaacaatcc
    26281 ctaatggtgc aggactttcc agtagcgctt cattagaatt attagtaggt gttgtattag
    26341 aagatctgtt tgatttaaaa acagatcgct tggaactagt ccaaacaggt aaaaaagtag
    26401 aaaatgaatt catcggtgtc aattcaggta tcatggatca gtttgccatc ggcttcggtg
    26461 agctagatca tgcaatctta ttagatacaa atacgctgaa atacgaaatg gttccagtga
    26521 aactagatgg ttatgcaatc gtcatcatga atacgaataa gcggcgggaa ttggcagatt
    26581 caaaatacaa tgaacgccgt agcgaatgcg aagaagcctt ggcacgtttg caaaaaactt
    26641 tgcctatctc ttctttagga gacttagatg aagaagaatt tgaatcaact attgaccaaa
    26701 tcggcgatga tacattgata cgcagagctc gccatgccgt ttctgaaaat cagcggactt
    26761 tgaaggcaaa agctgaatta gaagctggga acttagaagc atttggtcaa ctgttaaatg
    26821 attctcacca ctctcttcgc tatgattatg aagtaactgg gatcgaatta gatacactag
    26881 tagatgctgc tcaaaaacaa gaaggtgtct taggtgcacg aatgacagga gctggatttg
    26941 gtggctgtgc gattgctctt gtcaaagaag aaaatatacc tgccttcaaa aacaatgtct
    27001 atgatgaata catgaaagtt gtcggctatg ctccggaatt ttatgttgca cacattggaa
    27061 atgggacaac aaagatcgat ccagaagctg ttcatgtttg ataaaaaaat caacgatctc
    27121 agctaaaaac aaatagataa aaataacctc tcagcaattt ccaaatgtga gccttttgct
    27181 cgtatttgaa aattgctgtt ttttattgac acggaaagag aacgtgtgtt ctaattgtgt
    27241 tgaagaggtg attgttatgt gggcgaatca aaatccggta tttgtttatg aaaaagaacc
    27301 ttcaagagat attttatgta ttgactgcaa atctttttac gcctccgtag agtgcgttga
    27361 aaaggatctt gatcccctta caactaaatt agtagtcatg tcctatccgt ccgattcgac
    27421 agaaacacgg ggtagcggat taatcttggc ttccagtcct gcagcaaaaa aagcttacgg
    27481 catcaccaat atcagccgtg ccagagatct tcccttcccc tatccaagtg atttatatat
    27541 tgttgcccca aggatggcct attatatgga aaagaacaga gaaatcaatt ctatctataa
    27601 aaaatatgca gacgaagcga accatcatgt ctattccgtc gatgaaagct tccttgatgt
    27661 aacaaatagc atggcactct ttggtaaaac aaatgcgtac gacatggcta aactgatcca
    27721 taaagatgtg tttgagcaga ccggaatcta cacgactata ggaattggcg ataacccgct
    27781 acttgctaaa ctagccttag acaatggctc aaaagacgga aagcaaatgt ttgctgaatg
    27841 gcgttatgaa gatgtaccag aaaagttatg gaaaatctca gatatcactg acttttgggg
    27901 aatcggcaaa cgaacagcaa aacgtctgaa acaaatgggt atacattctg tttatgattt
    27961 agctcacgcg gattattatc acttgaaaag caagctaggg gtcatcggta ctcagcttta
    28021 tgcccatgct tggggcatcg atcgaagttt tttgggacaa gaatatacac caaaatcaaa
    28081 aagtatcgga aatagtcaaa tcctagatag agattataca agacgagaag aaatcgagat
    28141 cgttatcaaa gaaatggccg accaagtcgg cactcgcttg agacgatctg cagcaaaaac
    28201 acaagtagtc agcttatggg taggatactc tttaggctat cttgatccaa atggcaagac
    28261 cgggtttcac cagcaaatga aaatcgaagc gacaaatgct agcagagatc tagcagatgc
    28321 tttattgacc attttccacc agcattacca ctaccaggat attcggcgtg taggcgtgaa
    28381 ctgttccgac ctcgtatacg cgacaggttt acagcttaac ctttttgaag atcctgaaaa
    28441 gcagataaat gaagcgaaag ttgattttgt tgtcgatacg attagaaaaa aatacggctt
    28501 tcaatcaatc atccatgcgc atagtctctt gcaaggagga cgcgccatcg cacgtagttc
    28561 tctcgttggc gggcatgcag gtggtatgag tggattagaa ggtggaaaag atgagacgga
    28621 cagcaaaaaa attcattgac tataacgagt atcgagatcg gccatttgga ttaaaatggg
    28681 ggactgcttt tgcgatggaa gaactagtca acggtatcaa aaaaaatgaa gaagaagcac
    28741 gcaaacagcc tcttcctaaa caacaaatga cattgcaaga aatcgatagt atactgacag
    28801 aagccttttt atctcgtaaa gcagtaatca ttcagctcaa tttaaaagat gaatttggaa
    28861 gactcttgga tgaggtcgaa gggcacttca ttggtgaagc ctatgaagat tactttatga
    28921 ttgaccatca gccgatattg tgggaagacg tacggtatat tgagttaaag gaaacaaaaa
    28981 aatggtttgt gacatgagag gttgtgacag aagtgatcaa cttcaaaaaa taagaaagga
    29041 tttttcgaaa attgcttctt aaatttttgt ggaattttgg cttatttttc gaagaagcaa
    29101 cttctggaac aacgtatatt agatatcaga ggttgtgaaa aagtcgctta gttttgagta
    29161 acaagccaag gcgctgattt cacaacctct gtctatctat ccatctattc ggtaagattc
    29221 atgcatgacg tcttctttat ttagtatgta gagccctttt tcttctgacc attcaacata
    29281 aatcagctgt tttacatctg catagccttc tttcttcaag ttctccataa gccatgcttc
    29341 agtcaattga ttggactgaa gcactttatg ctgaatttgc ccttcatcta caagcaggat
    29401 cgataaagct ttgtcttcat ctgatttttt caatacactc atttgaccgg cattctctag
    29461 gataacatgt ttggcatttt caagaaaaaa gcattcttgc tgtcttaaga ttgctcgcaa
    29521 ctgctccatc tcgatatggt tatttgtcaa ctctgtcatg ttgatgacgc cgtctttgat
    29581 tagaacagat ggctcgcctt tgacccaacg attgaccttt tcattttttt ggacgatacg
    29641 ttcgatacca taaatcatta ctgcccaaag cgcaatggca aataggacat gccctacatg
    29701 gacattgtca tcataggttg attcttctaa gatcccacct aaaacaagcg tatagactaa
    29761 atcaaacggt gtgatttctg acatggattt cttcccaagc aaacgtacca ctaataataa
    29821 accgatcaac ccgaacacca gtttcattgt aattgaaaaa atcatttttt ctccccctaa
    29881 ctatctgtta attaaattat atatgctttc tcacgaacac gcatggaata tacaaggaag
    29941 aaatgtatcc ttttactaaa aaaaggactg tgacactgta gtgaccccca aaagttagac
    30001 ttttttggag tggagaaatc cactcctttt ttttatgctc taaaatgata tttttacaca
    30061 accgttacgg ttgttttacg aaattggacg agactttgcc agtttaattt ctgttttatc
    30121 cgttcattat tgtagtaata gatatagcta tcgatggctg attttaattc ctcgaaacag
    30181 ttataaactt tcccgtgaaa aatctcttgt tttaataagc caaaaaaatt ctccataagt
    30241 gaattatcta agcagttccc tttccgagac atgctttgaa agattttgta ctccttcaat
    30301 ttgtttctat aagctttcat ttgatacgcc caaccttgat ctgagtgaaa cgtacgacga
    30361 tagggacaat cgttagtggt ctggatagct tcctccaaac cttccattac cgctaatgca
    30421 ttgggctttt cagagatacg ataggataaa atctcactat tgaacatatc cataaaagga
    30481 tctagataca atttcttttg acggataatg cctttggcat ccacttcatg gtatttaaat
    30541 tcagttgtat ccgtcgtgat tttctgatgg cagatactgg tgtagaaacg acgatggatc
    30601 cgatttttgg ctactgctcc aacttttcct cgataagaat tgtagcgacg tgatttacgc
    30661 gtgtatgccg ttacttttat tcctagcttc ttgatcaagc gctgaacttt ctttttattg
    30721 atagagaaac cgcggtttct tagttcattg gtcatccgta aacagccata atccttgtgc
    30781 ttctcccgaa ttttaagcat ttccgcttca atctcttgat ctggattttt acggtccaat
    30841 cgcctttgcc atccaaataa tcatgaacga tctttaattt aagttcaaaa gtatatttaa
    30901 ccataaaaaa taccgacctc caaaagttag attttttggt ctaacttttg ggggtcggta
    30961 cacaaatcgt gtcacagtcc cttttttgaa aataaacggt gttcaaaagc ttgcatctgc
    31021 ggtaataagt ccagccaagt taaaaacata agaagctgtt tttacttggc tgttcttatt
    31081 acttgatgca aggcagcttt ttcacaacct cttttcaaat atttcgtttt cttattctac
    31141 aaatggttct tctcctaacg cttgttgagc ggctagattc aacatgctcc attgtcggtc
    31201 aaagcctggc tggaagaaga agtcagcttc tgctagttct tctaaagtca gtttgttttg
    31261 gatcgctagt gccaatacat ttccttgacc tgtaacatca taggtagata atactgctcc
    31321 tcctagcaat tgatgggtca ttggatccga gaataattgg atggacactt ttggatttcc
    31381 ttgttcttct ggtacatatt ttggtcgtaa cgtatcttca taataagaca ctcgtacatc
    31441 tactcctgct tttgctgctg taaagctatt caatccgctt gctgcaaaat gatagtcaaa
    31501 gacacttaat gcagaggaac ctacgactcc gccgaacggt ttgtttggta cttcttcaaa
    31561 aagatgtttt actacataac gtgcttctct acgtgcaaca gtcgctaaag cgatcggcat
    31621 ttttttgcgt gctgggatag aataagcaag tgtagcatct cctactgcat acacatctgg
    31681 aagattcgtt tgcaagtatt catttgtttg gatccagcca cgttcatcta agtcgacgat
    31741 cccttttaac cattctgtat ttgccttcac accggcagct tgaatgacta gatctgctgg
    31801 gatttctttt tcacttgttt tgattgcctc aacttttccg ttaccagtaa aagcttcgat
    31861 ttttgcattt gtcaaaactt caataccgtt ttcatttagg tgttgttcta aaatatctgt
    31921 catctcagca tctaaataag tgcctaaagg tctatcgatc acatcaagca atacgacttc
    31981 tttcccagct tttcggcttg cttctgctgc ttcgatccca atgtaacccg cacctacgac
    32041 agcgattttt ttaatagccg gatcatttaa tttttctttg attttggttg cccaattgta
    32101 tccacgcatc aagtagacat tttctagatc tgctcctggt actggcagat tgtttggttt
    32161 gacaccagaa ctcaaaatca atttgtcata aggatattct tttgtttcgt tatctgatgc
    32221 gctagtaacc gttactgttt ttttatcggc atcgatcgtt tttacttcgt gattatttaa
    32281 aatatgaaca ttggattgcg gaaagttttc tggtctgaaa ttacgtacat catttacatc
    32341 tgttaccttg tcttctaaat acagctccat accacatgac atgaaggaaa tatagtctcc
    32401 tgcttcaaat agcgtgatat ctacattttc accgtatcgt gtcaatagtt ccaagatcga
    32461 ttgatgccct ccatgagatg cacctacaat gacaactttg attttttcca ttgatgaaac
    32521 ctccttgaat attcttttaa aatcattcta aacaatttaa acttaacatt acattagtta
    32581 tgaatcaaaa gaaacgcgtt catttgaact aaatttaaaa aacaatcgtc tccttgcaga
    32641 atataccgca aaattaacga ttgttttttt gataaaatct atgaatcact gttctgttaa
    32701 aaagtctttg atccgtttgc aggcctcatg taatttttcc atgctgctag cataagaaat
    32761 ccggatataa ccttctcctt ctgggccaaa tgcaattcct gggatacacg caacttttgc
    32821 ctgttccgct aattctacac aaaactgcca agagtcagtt tgaatggcag ctgggagttt
    32881 gcaaaacaag taaaatgcac cgtttggctg ggtcacttca aatcctaaag gcgccaattg
    32941 ctggaccaga tagtctcttc gtgtttgata ttgctctttc atattctcgc tatctttcac
    33001 cccatttatt agcgcttcag ccgcagcttt ttgcgacatc gttgtagcgg cagtcaccag
    33061 atattgatgg actttaatta gttcgtcaat aagggctttt tgagcaaaaa taaagcccac
    33121 tcgccaacca gtcatcgcat gtgacttgga taacccgctt atcacgattg tttgttctgg
    33181 aagataagta gctatggaca tatgcgttcc actataagtc aattcagcat atacttcatc
    33241 acttataaca aataccggat atttttttaa aacctcagcg attgctttca attgttttgc
    33301 agacaatgtc gtcccagtag gattgttagg atagtttaaa atgactgctt tgacagctga
    33361 tccatattgt tcaaatgctc gttcaaattg ttccggctga cagacaaacc ctgtgtcaga
    33421 agtatctatc gggatcaatt cagcaccagc tagttccact aatggctgat atcctgaata
    33481 agcaggcgct ggaataagaa ccttgtctcc ttcttccaaa acagataaca acgcagaggc
    33541 aatcgcttcc gttgcaccaa ctgtcgtcaa aacttccgtt tgcggatcat aagttaatcc
    33601 ataacgctgt tgctgaaata tacaagccgc ttcccgcagt tcctctaatc ctctcattcc
    33661 ggtatagtga gaaaagtctt cttcaatcgc tgctattcct gcttgcttga catgttcagg
    33721 agttggaaaa tccggttctc ccagggtgag tttgatcaca tctggtatcg acgatatttg
    33781 ctgatcgaat tgtcgtattt ttgatacttc tattctagaa agcctaggac taaatcgatt
    33841 ggataaattc atcattattt actcgctcct cttttgaact gctatcgatt tttacaagaa
    33901 gattttctgt aaaaagaatc gttttgtacc attctacacc attttctaaa acatccatat
    33961 caaaatcgaa cgtcggatca tgtaaagcag gggtatcacc gacacctaaa aagaaaaata
    34021 cacatggata ttgttgcgta tatatgccaa aatcttcggc ttgaagaact ggagcatcta
    34081 attcatgtag tttgtttgaa tctaacagtg ctgcatataa gcctctatgg ttgattacag
    34141 ctggatagcc gtcattatag cgaaaagaaa tagtagctgt agagtgaaac tgttctgcta
    34201 aatggtctaa tcccctcttc aaataatttt gcatatctga actgtaagaa cggatacttc
    34261 cggatacaat aacttctcca gctaaaacat ttcggatcgt tccaccttgg atttggccaa
    34321 atttcattag atgattccac tctgccggta attgccggtc aaaatcataa acattcttca
    34381 aaaatcgtac agctgcctcc agactatcga ttcctttttc actagaagca atatgtgcag
    34441 actggccttt aatgataatg tctgtttcac tgctttgtgc catcaaaggt cctggtcgag
    34501 agaaaacttc tcccttagct agtccaggcc atagatgaaa gccaaatatt gcttgtactt
    34561 catatttatc caacaatcct gactgaataa cgctttgtgc gccaccggaa atttcttctg
    34621 atggctgata gatcagtact acattataaa taagatcctc aatgtgttta gttataaagt
    34681 cagtcaaccc taaaagcatc gccatatgtc cgtcatgacc acatgcatgc atataacctt
    34741 catgcttaga agcaaaagag agattcgttt cttctttgac tggcagtgca tcgatatctg
    34801 ttcgaaaagc aatcgtttct tcttgctgat tatcaaaata aaggagtagt cctgtttcgc
    34861 cgatttcatg gataacggcc tcgctgtttt ttacttgttc atataaatat ttttttgtct
    34921 tgaattcatg aaacccgatt tcaggaattt gatggagtgc cattcgatat tctttcagca
    34981 tccgtattca ccatcccttc atagataccc ttcactactg tttcatattg attattcggt
    35041 acaccgatga tcagattcaa ctcctgtgct ccttgtgata agatcgatgt gcgaatttct
    35101 aatttgttca atatcgataa cactttccca gataatccaa tcaattcttt atgcggaccc
    35161 ccaacgacag agatcaaagc taagtcttcg atcacgacga tttcttccac gccaagtgtt
    35221 tcttttaatt ctttcgtgat gagaaataac ttatcggcaa tcgcttctgc tgagacgatc
    35281 actccgatat tgtcgatccc tgaaggaata tgttcgattg atatctcatg tttagcaaaa
    35341 atgctcattg ctttccagat aaacccgatt tcatcggaca tatgacgttt gaataaagtg
    35401 atggaaagaa aatccttgcg tccagctatt cctgtcagtc cattttcctt ttctatttcg
    35461 tgatttgata tttttgtccc ttgagcgaaa ggatcattgg tattttttat ttggatgggg
    35521 atatcagcct cttgaactgg gaaaacagct gcttcatgaa gaacgttagc ccccatataa
    35581 gccatctctc tcagttctct aaaagagatt tcctcgatga ttttaggatg atcgatgatt
    35641 cgcggatcag ccatcatgat tcctgaaaca tccgtccaat tctcataact ttccgcttgc
    35701 aacatcttcg ccagtatcgc gccggtaatg tcgcttcccc cacggcccaa taatttttct
    35761 tttcctgcag ggttcgcccc gtaaaaccct ggaacaacca ttttcggata tcttttaaat
    35821 gcttttgtga tttcctgtgc tgttttttcc tgatcgattt tcccatcata gtcaaagaaa
    35881 atcaggtctt ttgcgtcaat aaactggtaa ccaagatact cagccatcag ttgagcagtc
    35941 agatattcac ctctacttac taaataatct tcagttatct tttcgtcttc cagttgtttc
    36001 tgtatgcgtg ctagttcatc ttcaataggt aactgcaggg caagaacatc tcttacttga
    36061 atgaaacgat cacaaatcct tttccaaagg ggtgtccaat caacatgatg ctgaaggtaa
    36121 gcataaatca aataaagtaa gtctgttact ttgtcatcat ctgacgtacg tttgcctaaa
    36181 gcagaaacaa cgatcacttg gcgattggga tctgaaagaa caattgtacg gacttttttg
    36241 aattgctctt catgagacat cgatgttccg ccgaatttcg ctactttcag cgtattactc
    36301 atcttgccac ctccgctatt ttctgcatta aagctgcagc aatctgtacg gcattcgcag
    36361 cggctccttt gcgtatgtta tcggcagtcg tatagaacaa caatccgttc tctaaagaag
    36421 tgtcttttct gatcctccca acataaacca tatctgttcc tctagcaaga atgctcgtcg
    36481 gatatttatg tgctgctaga tcatcttcta attgaatccc tggaaactgg ctgagacact
    36541 ctctaatttc ttccgtcgta aactcttttt gcagttgaac tgccacagag actccatgtc
    36601 cattttcgat tggcacacgt acgcaggttg ctgatactgg caaagcaggc tgatgcagaa
    36661 tcttacgggt ctcatttatc attttctgtt cttcttttgt atacccattt tccaaaggct
    36721 gatcgatttc cggaatcacc gtttggctaa tattataagg atacaaaact ggttcctcgt
    36781 cattttgcgt acgatgaaga tcttcaatgc ctttttgccc ggaaccagaa actgcttgat
    36841 aggtcgaata attgactcgc tggataccaa aggcttcttg taaagcttta agcggaagta
    36901 ccgcttgaat ggttgaacaa tttggatttg caatcagccg attcaatgta tagtcttcca
    36961 gattgacctc tggaacgatt aatggaatat ccgaatcttc ccgccatgct gaggaattat
    37021 ctatgacaaa tagtccctga cttcgtgcga ttggcgcaaa ctctttggat acagaagcac
    37081 ctgcagaaaa tagcgctaaa tcatatcctt caaatgaagt ttctgtcaat tcctgtacag
    37141 tgtgtttctt tttcttgaat acacaaactt taccggctga acgttttgaa gctaataatt
    37201 tcaatcgtcc tactggaaaa tcatattctt ctaacacttt gagcatcgtt tggccgacta
    37261 atccggttgc ccccacaata caggtatcta tttcgcgcat ttttctccat ctcctctata
    37321 attcgcgtaa cgcagcaatc aatgctgtat tttcttttgt ctgatcatca cttattttta
    37381 atacacgtgc aggtattcca ccgacaacag tttctgctgc cacatcttct aaaaccactg
    37441 ctcctgctgc cacgactgca tcttttccga tatggacacc ttcaacaatc actgcattcg
    37501 cacctaccag tacgccgtct tctacgataa ccggtttggc cgatgctggt tcgatcacac
    37561 ctgctaagac agctcctgca ccaatatggc agtttttgcc cactgtcgct cgtccaccta
    37621 agacagcacc catatcaatc atcgtgtttt caccgattac tgcaccaata ttgataatcg
    37681 ctcccatcat gatcacggca ttgttgccga ttgacacttg atctctgata atagcacctg
    37741 gttcgatacg agcattaatt tttttaatat ctagcaaagg aactgcgctg tatcttgcag
    37801 cagtttcgat ttcgatttca atgatttttt ctgattcagc ttctaaaacc ggagcaatcg
    37861 tctcatagtc accaaaaaca acgaagctgc ttccttcacc aaaaacttta ctttctttaa
    37921 attcgattgg ctcggttaca ttcagataga ctttcacagg cgtcttttta gatgccgttt
    37981 gaatgtagcg gatgatttct tgagcttcca cgttttttac acccctttgt ccattaataa
    38041 atcttctaat ttgtaataac ctggtgactg atctttcaac cagtccgctg cttctactgc
    38101 gcctgcagca aagattcgat tagaaaaaga ttcatgtttg atcgtaaata tttcatcagt
    38161 agcagcaaac aatacatcat gttcaccagg taaagaacct gcacgaatac tgtgtacacc
    38221 aatttggttt tcttctcttt ttttcccttg ccagttgtat acgggctgca gcttttgcac
    38281 ttcttggatt gtttgaagca gcatatttgc agtaccagat ggtgcatctt ttttacgact
    38341 atgatgtttt tcaatcagtt cgatctgcca gccttgcaac attgcagctg cttgcttgat
    38401 tagttgattc atcaccatga tgccgaacga aaaattagca ctatacatca caggtacatg
    38461 tttggcatgt tcttttattt cttggaactg tgattgtgta taacctgtcg tgccaatgac
    38521 taacggaagt tgatatgata agctatacga aaggattttc tctaaattat ctggatgaga
    38581 aaaatcaata agcagttctg gcagttccgt aaaagcaagc gtagttgctt ctttaggtgc
    38641 cgtccgtaaa agaaggaccg tatctcctct ttcttgtgca acttcttcga ctctatttcc
    38701 catctgtcca ctgccaatca gtccgatttt catttttcaa ccgtcctttc ttttaacaaa
    38761 agctgagcta attgtttctt tttctctttt gaaagagaaa ctaaaggcag gcgtagaggt
    38821 ccggaaggta agtctaataa tgacatggct gctttgacag gaataggatt ggtctcactg
    38881 aacaaggcat ggatcagttc aagtgcattt aattgctttt cttttgcttg ctgccatctt
    38941 ccgtcctgcg tatcttttac taattcatgg actattttag gttggatatt cgcccataca
    39001 cttattacac cgcttcctcc tacactcatt actggtagga tcaaatcatc atttccactg
    39061 taaaggaaga attcttctcc aatcaaccga gcggcatcca tcacataagc catatctcct
    39121 gaggcttctt tcaaaccaat gatattagga tgttctgcta aatttactaa tacatggatt
    39181 ggaatcgaca tgcctgttct agaaggaaca ttatacaaaa taagcggaat cggtgaggct
    39241 tctgcaattg ctgtaaaatg agcagctagt cctgcatcac ttgttttgtt gtagtaaggg
    39301 gtgatgacca aaagtgcgtc tgcccccaaa gaagcaaaat gcttcgcttt ttcaatcgtt
    39361 tctttcgtat tattcgttcc agctcctgca atcaccggca cacggccagc cactttcttt
    39421 actgtcagtt gaaggatctg ctcctcctca gattgtgtga gcgtagaaga ttctcctgtt
    39481 gtacctaaaa ctaataatcc atctgtttgt tcatctaaat ggaattggat caatttttcc
    39541 aaaccagcat aatctactga tccctcttca ttcatcggcg tgatcagcgc cacgatcgaa
    39601 ccttttatca tcttcattcc tccaatattc ttgtccattc atgaactgct gggccagcca
    39661 tttgtatcgc atcctcacca gagatcatca agtctccttg ttccaagtga acaactacct
    39721 gatctgctga aattttccca gtttccttag caaccacata agaggcacag caacctgtac
    39781 cgcaagcaag tgtccaacct actcctcttt cataggtacg gacgatcaat tcttgttcat
    39841 tgactacttc tacaaagttg acattggttt tttctttgaa caaaggatga tgacagatca
    39901 gttcacctct ttttctccag acttcctcac gcgcattttc aacaaaaaca acggtatgaa
    39961 tcgttcctaa aaataaacta gtgatcgtta ctttttcacc attgatctct atttcctggt
    40021 tttttattgg ataagtttga ttagctttga ttttttccgg agaatcatct ggcactccca
    40081 tatctacgct gcaataaaaa ggtgagggat ccaacaccgt aatttttctt gtgcctgcta
    40141 atgtctctac gttgaattcc tgttcattca tcatgttctg atcatttacg tatcgagcaa
    40201 aacagcgaat gccatttccg cacatcggcg cgcggctgcc atctttgttg taatagatca
    40261 tttccaacgg atcgattttt acggcgatca atccgtctat atcatatttt tcttttgtgc
    40321 ataaagaagc ggctaattga ctataatctg tgtcttctgc gtaatctaat aagataaaat
    40381 catttccgca gccattatat ttatgaagga tcataggaaa cttcccccct tagtagatca
    40441 gaaaatgctt gtctgcgaac aatcagtctt gattggccat tattgacaaa aacaactgct
    40501 ggtcgtgtcg ctcgattgta gttgctgctc atcgagtatc cataagctcc cgtggaataa
    40561 acagctaaaa gatcacccga ttctgctttc ggcaaataag cttctttaat taccacatcg
    40621 cctgattcac acatttttcc tgcaatcgtc actttctctg ttttttcttc cgacagtttt
    40681 gctgctaaat cacaatcgta ttctgcctga tacagagctg gacggatatt atctgtcatc
    40741 ccgccatcta caaagtaata ttttttatgt ggtgtctttt tgatgaaacc aatcgtgtat
    40801 agtgttgtac cagcttctcc aacaatactt ctacccggtt cgatcagtaa ttgacgaatg
    40861 gtcagttttc gtttttccaa agcttcttcc gtatattcaa tcagtttttt tagtgcctct
    40921 tcgactggga tcggctgatc attttgtgta taacgaatcc caaaccctcc gccaagattc
    40981 aaggaaagag gttggtcaaa atcggttaag taattcgtca atttgtcgat ttcagctaac
    41041 caagcagtaa catcaaaaat ttgtgacccg atatgagcat gaaatccttc taactctaga
    41101 tagctgcttt cttttatcaa ctgaagggct tgttggcact ctttactttc atagctcatg
    41161 ccgaattttg aatcaatatg cgcagtgacg atatattcat gagtatgtgc ttctactccg
    41221 acattcaacc gaagcatgat acagattttt tttaaatagc gttggcttaa ttctgctaat
    41281 aattcaactt ccatcaaatt atcggcaaca atatgcaaca aatcattttc aagtgcatag
    41341 atcagttcct ctggcgtctt gttgttacca tggaagtaga tagtatctct aggaaaatca
    41401 gcttgcaaag cggtatagat ttccccacca ctgacaacat ctagcccgaa tccatattca
    41461 cgaactaaat gcagcatctc aatcgtttgg aatgctttag aggcgtaaag cacttttgta
    41521 tcaaaacgtt tcgatacaaa gcctcgcttg aatgacagca tcgtttgtct catcttttct
    41581 tcatcataca catacagagg tgtcttatac ttttctgcca atgtgcttgc tgtgactccg
    41641 ccaattatca attctgtcat tttttcattc ctcttttcac tttttttccg tttttattgg
    41701 aatttcattt gataaagatt tgaattttat tggaataata ttaaacaaaa ttttctgaat
    41761 tgtctagtat atttcgaaat atttttttaa aaataagaat aaaaatggtt ataaaaacaa
    41821 aatacccgaa ctattagaag ctatttatac ataaaaacat aaattcaaca ctatttagtg
    41881 atgaaaaaat attttcgctt caatatagtt cggaatagtt cggatatttt caattttatg
    41941 aatcatttca atttcttcat aaataagtgc agttttttct ttctctagct tttgccattc
    42001 atctttcaaa atataaataa aatcaaatac ttttttattt ttcaatttgc tgattccaca
    42061 aaaaacctct tgaaaggcag atccgatgat ctgcctttca agaggtcaag ctctgttttc
    42121 aaattcttat caatccgtta gcgaattatt ttgacgcacg ttttacataa gaaccttctg
    42181 ctgtattgat ttccaacaat tcatctgttt cgatgaagtc aggaacattg actactaagc
    42241 cagtttccat tgtcgctggt ttacctgaac cagtgactgt tgcacctttg atggaaggtt
    42301 gtgtttccac aacacgtaat acgacagttg ttggtaattg aacgccgatg acttcgctac
    42361 cgaagaattg gatttttact tccatgtttt ctaggatata tttcatttct tcttctactg
    42421 tttctacagg aatttcatat tgctcatatg tttccaaatc catgaagaaa gctgtatcat
    42481 ccatcgtgta caaatattgt acaggttttg tgtcgatatg tgctttttca aatttttctt
    42541 ctggtctgaa cgttgtgtcg tatgttgcac ctgaacggac atctttcagt ttcatacgca
    42601 taactgtatt tcctttacca ggtttatggt ggcttgcatc cagaacttta atcagtttgc
    42661 cgtcttgtac gaaagtcata ccggctctta aatcacttgc tgagatcatt atttttgctc
    42721 cttcttttct ttatcataat caactttatt gtatcagaca accggccaga aaactagagt
    42781 attctctatc ttttaaggtc tcatgcctat ttgtcagaaa aataaacacg ggtaaacgat
    42841 gctatcgaaa tatttttttc tttcaagcct ttgactttta ttttttttca tgctatcgtt
    42901 aataaaaatt ttacttggag ggatacacat gacagtcagc aaccaaaaac aattgaatcg
    42961 ttgctgttgt atggtgcata aaagcagcat actatttgtc atgtctatta attgcccttc
    43021 atagaatgag taccaggtaa cttatctttt tatctactca atttttctct atgtctttca
    43081 aggagctgat ttaatagtca gctccttttt ttattatctt tttttaggag gcccatatga
    43141 ttatctcgac aattacagaa gctattggtt ccacaccgct ttatcgcttt gacaatcagc
    43201 actattctat gcctaaaggt tctgctattt atgcaaaact agaatattta aatcctggag
    43261 gaagtatcaa agatagattg ggcagttatt tgatcaaaga aggatttgcc caaggaaaaa
    43321 tcaatgaaaa aacgacgatc atcgaaccaa ctgccggaaa tacaggaatt gggatcgctc
    43381 tggccgcact cacatacaaa ttaagaacgg tttttgttgt tccagagaag tttagcttag
    43441 aaaaacaaca attgatgaaa gcattgggag caaagatcat ccattctcct agtgagcaag
    43501 gaatcatcgg tgccatcagc aaaagtaaaa aacttgcaga ggagatatca aacagctatc
    43561 tgcctcttca atttgaaaat aaagataatc ctgctgctta ctatcatacg ttagggccag
    43621 aaatctttca tgaaatcaaa gaaaatatcc atagttttgt agcaggaatt gggagtggtg
    43681 gaacctttgc tggaacttct acctttttga aagaaaaata tcccgacatt cgaataatcg
    43741 gtgtagaacc agagggctct gtgttaaatg gtggtgatcc agcccctcac gaaattgagg
    43801 gtatcggtgt agaattcatt ccgccgtttc tttctcccct ttcaatcaat cagatcgaga
    43861 caatctctga tgtagaaggg tttaaccata ctaggcagtt agcacgagaa caaggactat
    43921 tagttggaag ttcgagtggt gcggcttttg cagcagcatt aagagaaatt cgtcgtttac
    43981 cacctggtca tcgtgtcgtt acgatttttc cagacgcagc agaccgctat ttatcaaaaa
    44041 acatttactt
//
LOCUS       DACDLM010000018        43589 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.018, whole genome shotgun sequence.
ACCESSION   DACDLM010000018 DACDLM010000000
VERSION     DACDLM010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 43589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43589
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.018"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            160..840
                     /locus_tag="IV356_001002"
     CDS             160..840
                     /locus_tag="IV356_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAP9014707.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            930..1964
                     /locus_tag="IV356_001003"
     CDS             930..1964
                     /locus_tag="IV356_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAP9014708.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            1978..2313
                     /locus_tag="IV356_001004"
     CDS             1978..2313
                     /locus_tag="IV356_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014709.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            2297..4777
                     /locus_tag="IV356_001005"
     CDS             2297..4777
                     /locus_tag="IV356_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014710.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            4833..6392
                     /locus_tag="IV356_001006"
     CDS             4833..6392
                     /locus_tag="IV356_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP9014711.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            6389..7753
                     /locus_tag="IV356_001007"
     CDS             6389..7753
                     /locus_tag="IV356_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP9014712.1"
                     /translation="MKIVIIGASHEGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            7924..8994
                     /locus_tag="IV356_001008"
     CDS             7924..8994
                     /locus_tag="IV356_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9014713.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            9009..9677
                     /locus_tag="IV356_001009"
     CDS             9009..9677
                     /locus_tag="IV356_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9014714.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            9697..10275
                     /locus_tag="IV356_001010"
     CDS             9697..10275
                     /locus_tag="IV356_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP9014715.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            10676..11587
                     /locus_tag="IV356_001011"
     CDS             10676..11587
                     /locus_tag="IV356_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP9014716.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(11965..12882)
                     /locus_tag="IV356_001012"
     CDS             complement(11965..12882)
                     /locus_tag="IV356_001012"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HAP9014717.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELDKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            13084..13521
                     /gene="zapA"
                     /locus_tag="IV356_001013"
     CDS             13084..13521
                     /gene="zapA"
                     /locus_tag="IV356_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HAP9014718.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            13579..14127
                     /locus_tag="IV356_001014"
     CDS             13579..14127
                     /locus_tag="IV356_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HAP9014719.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            14242..16602
                     /locus_tag="IV356_001015"
     CDS             14242..16602
                     /locus_tag="IV356_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HAP9014720.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKIENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNTYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            16689..17003
                     /gene="trxA"
                     /locus_tag="IV356_001016"
     CDS             16689..17003
                     /gene="trxA"
                     /locus_tag="IV356_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HAP9014721.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            17185..18963
                     /gene="uvrC"
                     /locus_tag="IV356_001017"
     CDS             17185..18963
                     /gene="uvrC"
                     /locus_tag="IV356_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HAP9014722.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMVKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            19108..20007
                     /locus_tag="IV356_001018"
     CDS             19108..20007
                     /locus_tag="IV356_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9014723.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            20000..21262
                     /locus_tag="IV356_001019"
     CDS             20000..21262
                     /locus_tag="IV356_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9014724.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPIRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            21423..23321
                     /locus_tag="IV356_001020"
     CDS             21423..23321
                     /locus_tag="IV356_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HAP9014725.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(23651..24370)
                     /locus_tag="IV356_001021"
     CDS             complement(23651..24370)
                     /locus_tag="IV356_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HAP9014726.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLVEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            24707..25039
                     /locus_tag="IV356_001022"
     CDS             24707..25039
                     /locus_tag="IV356_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014727.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            25026..27029
                     /locus_tag="IV356_001023"
     CDS             25026..27029
                     /locus_tag="IV356_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HAP9014728.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            27048..27518
                     /locus_tag="IV356_001024"
     CDS             27048..27518
                     /locus_tag="IV356_001024"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HAP9014729.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            27539..28123
                     /locus_tag="IV356_001025"
     CDS             27539..28123
                     /locus_tag="IV356_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HAP9014730.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            28138..29124
                     /locus_tag="IV356_001026"
     CDS             28138..29124
                     /locus_tag="IV356_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HAP9014731.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            29114..29425
                     /locus_tag="IV356_001027"
     CDS             29114..29425
                     /locus_tag="IV356_001027"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HAP9014732.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            29447..31228
                     /locus_tag="IV356_001028"
     CDS             29447..31228
                     /locus_tag="IV356_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HAP9014733.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            31221..32597
                     /locus_tag="IV356_001029"
     CDS             31221..32597
                     /locus_tag="IV356_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HAP9014734.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            32604..33239
                     /locus_tag="IV356_001030"
     CDS             32604..33239
                     /locus_tag="IV356_001030"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HAP9014735.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            33269..34624
                     /locus_tag="IV356_001031"
     CDS             33269..34624
                     /locus_tag="IV356_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HAP9014736.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(34816..36210)
                     /locus_tag="IV356_001032"
     CDS             complement(34816..36210)
                     /locus_tag="IV356_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAP9014737.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            36302..37273
                     /locus_tag="IV356_001033"
     CDS             36302..37273
                     /locus_tag="IV356_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HAP9014738.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            37270..38052
                     /locus_tag="IV356_001034"
     CDS             37270..38052
                     /locus_tag="IV356_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HAP9014739.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(38221..38592)
                     /locus_tag="IV356_001035"
     CDS             complement(38221..38592)
                     /locus_tag="IV356_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAP9014740.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            38726..39169
                     /locus_tag="IV356_001036"
     CDS             38726..39169
                     /locus_tag="IV356_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAP9014741.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(39212..40021)
                     /gene="yidA"
                     /locus_tag="IV356_001037"
     CDS             complement(39212..40021)
                     /gene="yidA"
                     /locus_tag="IV356_001037"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HAP9014742.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(40040..41407)
                     /locus_tag="IV356_001038"
     CDS             complement(40040..41407)
                     /locus_tag="IV356_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP9014743.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(41391..42221)
                     /locus_tag="IV356_001039"
     CDS             complement(41391..42221)
                     /locus_tag="IV356_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HAP9014744.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLEDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            42384..42821
                     /locus_tag="IV356_001040"
     CDS             42384..42821
                     /locus_tag="IV356_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HAP9014745.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            42897..43517
                     /locus_tag="IV356_001041"
     CDS             42897..43517
                     /locus_tag="IV356_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HAP9014746.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
BASE COUNT        14278 a         7488 c         9251 g        12572 t
ORIGIN      
        1 ttaataaaaa aggaagaata ttcatgtaaa cgattttatt gtttttttct cttttataca
       61 aaaagggtca taatttcaag taagcggatg aattcatgag gattttttgc atactgtctc
      121 tactatactt aggtcactaa gaaaaaggag tgatttatta tgaaaaagaa catgattggg
      181 acattattac tttcaacact tcttctaggc ggcttggcaa caccagcttt tgctgagggt
      241 caagcgactt caaaaggaga tattaccttt actgaaccaa caaataccgt ggagcctctt
      301 aaccctactg atccttcaaa accagtagag ccagcagatc cggaaaatcc agcaactggc
      361 cagacaggtc ctttaacact ggatgtagtt cccgaattgc catttggtac acacgagatt
      421 gaaagcggaa caaaaacgta tcaagtagac gcttcaaaaa acgatacacc ttatctccaa
      481 gtatcagatc gtcgaggtgt aggtgcagat ggccaagcac aagggtggaa cgtgacagtt
      541 tcggtttcag attttgtaaa cggttcacaa gttttgcaag gcgctgaatt agattttgga
      601 acatccactg ttaaaagtac gtcagataac gaatccactg gaccaactag tcaaactgta
      661 actgggttga gtaaagcaag tgcagcgaca ccaatattta cagcagcaaa agatcaaggt
      721 ctgggaacat ggctttctgt ttatgatcca gcaaatatca cactgaaagt gccgaaagca
      781 gcagctggaa cattcacggc tgatttgact tggaacctcg tggctggccc agtagcatag
      841 agtatgaaat aaattcaaca aactgcggtg aaaatactat aggtgaagga ttttttaccg
      901 cagttgttgt tgaaaggatg tggtggacaa tgaatcaaag taaacgactg tttgtttcgt
      961 ttttttctat tttaagtcta tttttcattt ttccgtcaat cagccaagca aaggattcag
     1021 caggagactt tggaatcaaa ccggtatttc cagagaacca aatagataaa gcaatcggtt
     1081 attttgattt attagtggca ccggaacaaa atcagacact agaagtaatt atcagcaatt
     1141 cttcagatga agaacgaaca tttgaggtct ctgtcaatcc ggcggtaacg agtgatggtg
     1201 gaacgatcga ttatagtcaa aaaaacccaa cgttagatga gacattgccg tttgatgtcc
     1261 gtgacgtttt gctcattgcg aaaaaggaaa tcaatgtatc agcacatgca gaaacaactg
     1321 tacctataga agtgaaaatc ccagcaaaaa gctttaaggg acgtgtatta gcgggtattc
     1381 atgtttcacc taaagaagaa gctgaaacag aaaatgctac agaaggagca caaatcaaaa
     1441 atcgtattgc ttataatctc gcagtcgttt tacaagaaag tcaagagacg atagaaccgg
     1501 atctgaaact tttatcagga gatttggacg aggtcaacgc aaagccaact gttcagcttc
     1561 gtttccaaaa tcctcagcct aggattatca gcaatttgat atttacgagc aagatctttt
     1621 atgaaaatca gctttatatt gaaaatacgt ctaatgcatt tttagttgca ccaaattcga
     1681 attttcactt gaatcttgat ttagctggtg ataaagcaaa agccggcgat taccgcgcag
     1741 aaatcatagc aaaatcaggc gacagtaatg aatggcgatt tacacaaaac tttacgatca
     1801 aaaaagaaaa agcacaaaaa gtaaatgaaa attccgtttt tgcagtacaa gaacaatctt
     1861 tcccatggct ttatgcagga ttggttgctg cagttctagt gttatggttg attttgctgt
     1921 ttttgtgggt ccacaagaaa aagaaaaaag gagaaacaac atgatgaggt gatttcgttg
     1981 aaaacatcga tcttattggg agggattatt gcaagtttgc tgttcttcag ctggcaagag
     2041 ccagtccaag cagataccaa aagttcaggt acgattacat tttatgatct aagtccaatt
     2101 ccgcatccaa gtggttcagt caatggcgca tcaaaacagc agacacagct accgatttat
     2161 aaagaatcta atcaacatgg cgtattcccg gagacgaatg aacaaaagat ccgttttctt
     2221 tatttgatca ttggtataga attatggctt cttgcgtggt tgttgttatg gagaagaaag
     2281 gaaaaggagg atgaacatgt tgctacaaaa taaattttca ttttttcgct ccttcttttt
     2341 tacttcgctt tttgttttaa gtatatttat cttttcacct tcggcagaag ctgttggagc
     2401 aacgcctcct gccatttctt atgatccata cacgtatgaa aatatcgtac ctccaaatgg
     2461 tggacgtagt gcagtcaatg gcgggaagct tgtccaacta actggggcta accaattgcc
     2521 taaattgact gctacttatt tgaacgatgg ttcaaatgat ccttggaaag gtggcacggt
     2581 ccgttttcat tgggaaagcc atgtgaaact aacaaatgta cttgatttgg tgaatatcac
     2641 tgcacaagga tttgcatttg tggcgatcat caatttgccg gaacatgtat caagcagtga
     2701 tgtattaaaa gcaattgact ggaacaacgc ctacttgtat attgccggtg cccccatcaa
     2761 ggttactagc ggaagtttat tatcagcagg aagccatacc ttgcgttttg ggatggggtc
     2821 gtgggataca aatactctat tgacagatat tattgctatt attacgcgag gcgaattcaa
     2881 cgtggacgat atcccgcttc aatttgatgt tacagctaat gtcgcgaaga tgacagaaaa
     2941 cggagataaa tatgatacga gtccaaacaa aattttgacc aagggtaaat tacaaccttc
     3001 tatgtctaaa aaggccgttt tttctgttga tttttatgat tcgaataata ttatccaaga
     3061 tcgtatgttc aattcgattt tagctccagc tgcaggtaga ttttatccta aattaactgg
     3121 cggaaacttg aatccaggag catatgcatt ttctgcaagt gcagagataa atacgtggaa
     3181 tagttacatc tcaccaagtg attcaacagg aaaatataat acatttgctg ataccacaga
     3241 atacgtggat ggaaataacc agaaccttcc aggctctacc aatagtcgga cattgacgat
     3301 ggggctgact gaaggacgtt ttgatcagtt gccatttagt cgctttgatc gcgtagtcaa
     3361 ctattttaca ggaaaaaacg ttacacaagg agcaatactg actcatactc cagcaagcac
     3421 aagtggattg aatcagacag ccaatatcgt gtacagtggg aaagatgcgc aaggcggatt
     3481 gctttctcct gttgctttaa aggtattgga gcagtacaag ctagacggaa cggttttacc
     3541 aacaaactta acagccgata gtcagtgggg aaagctcctt tcttctgcat cgtaccaagt
     3601 cacggccaat tggtcagcaa ctgaactaaa aaagggttcg atccattaca ggctttattc
     3661 gaaaggaacc caaaaattag cgacaggatg gacagatcaa cttttccaaa cgatccaatc
     3721 aaataacggg ggtgtaaata cagctacttc tacactacct gcattggctt cagggcaata
     3781 ttattttgat tatcgcttgg tggacgatgt acttactaac atgtatccgt cttttgcgta
     3841 caaatggcag tctgaacaag ctggaatcac cactcttcct caaataacag tggctaattt
     3901 tccatctgtg agtgcagata gtcagctaaa aaaccttagc agacaacctg agacaggaga
     3961 tcccctgtct gctctatcag gagatacgat tcaagaaaat gtgacattca cgttaacaaa
     4021 atctggggat gcgataaccg acaaaaaaat cacgatctca cttcctgaaa atactactta
     4081 tatcaatggt tccttaaaat taaatggtac aactatcgca gataccggca ttcaacaagg
     4141 agtttctgtc ccagcagatc tattgagcaa aataggagat accattcatc ttacttacaa
     4201 ctatcaatta aatactgtag atacttcttt acaatccgtc agcatactga caaaggcagc
     4261 tgtactttcc agcaatatta cattagcaga tggtgctaag cttcctaacc cagttgtcca
     4321 aacatctgct aaaacaattc ttgtccccaa acaagaatta acattagtta atgtaccaga
     4381 tgattttaca tttggtaacg atctccccaa accgttgaag acaagttatt atgaatcaaa
     4441 aggcgatttt tcttttgatg tgcgggatac tcggcttcca agcacgtctc cttggcaact
     4501 gacaggtaca ttgacttctt tatttaagaa tgatcaaggt caagaattaa gcggaacaaa
     4561 attatacttc aatcattctg gatcaaagca attgattcag caaggtcaaa acacgttgat
     4621 ttatgagagt gatggaacag ctaaaggaga ggttctcgtt gactttcccg ataccgatgg
     4681 tttactctta gaggtaaata gcagtacgaa tgctcaacct ggcgcaacgt atcaaggcat
     4741 ggtcacatgg gaactgacag ctgggccaac cagctaagtg attagaattt gtatggatct
     4801 gtgataactg tcacagatcc tctttttcaa ggatgagaag gaaacttctg ctgttaaaat
     4861 cagaaatgct tgaaggagtg gacttggaac ttttcagttt gcttgaaaaa aatgaacaac
     4921 ggcaaatcaa acttttccaa cttttattag aggaaaaagg agaggtttcc gttaataacg
     4981 tacttacccg cttatcagtt gatcgggcta ccttgaaaga agatctgttt tatttacaag
     5041 ctaacttgga aaatatcaaa caattggaaa ttgttatcca agaagggaat attttattaa
     5101 tcagacatgg aaatatagca gcagtcgatg tttattatca ttgttacttg cgctattcta
     5161 caaaatatca gatacttctt tatctgttgg aaaatggctc atttgatcgg cagaaacttg
     5221 tcatggaact taatatcagt tcggctactt tgtctcgcag agtgaaggaa ttaaatgatt
     5281 ctttaaatga gtttcatctg aaaataaaaa gcgggcggct gaccggtcca gaaagtcaaa
     5341 ttcgttattt ttatttccaa ttattttggt ttggacgtcc ctatcttgaa aacaaaaaag
     5401 aatacagtga tttatcagga aacacttttt tagatctgct gcaaaaagag tttagttttg
     5461 ctattacaga agaaggacga ttgaaatttg aaatatggct ttccattatg aagaagcgaa
     5521 tgcgctgtac gaaaaaatcc aaaccagatt atagcaatct tcctgttgga ttgtttcaaa
     5581 cgacacaatt tttattggac ctccatacat ttttgacccg ttacttcttt caatatgcct
     5641 ttccttggaa tcaaaatgaa acgttggttt tttatctttt catgatcagt aactttacat
     5701 tagatacaca taactcgcat gtccaggagt ttttgataag cgaaaaatac aaagacgacg
     5761 tagtagctca attgaatcga acgtttaaac aatcgataga agaatatttc tctttttatg
     5821 tttttccaga agagatttcg caaaagattg cgttgacagt gatgcaaaat cacgctcatt
     5881 ttgcctattt tagaggatgg atgaatattt ttggccaaga aggattaaaa cagcggttaa
     5941 ctgaagtaga agataaacaa ttcctggttt tatgtgaaag attggtcaga caaacatttg
     6001 ctattgttga ttttactgaa gtagacgagg aaaatgcccg ctttgaatta tttgctcgct
     6061 atgcatctat tttacggacg ctgatcaagc agttagaatt acgtctgcaa attgcttatg
     6121 atcttcctta tgaaaggcta atggcggata tcgtgaaaga aatcatccag gaacaattgc
     6181 tgaatacgat caaatatgat ttagtcgaat acgagaaaga aaagcagtat gatatcattt
     6241 tgactagcca attgaaagag tacccgtcac agaagtccgc taaagttttt gtattcacta
     6301 gcaacgaata taattatgat ttcccctatt tgaaccaatt tttaaaagaa tgttatttag
     6361 aaaaattgaa tttaaggatg aataaaacat gaaaatcgtg atcattggtg cttcccatga
     6421 aggcatcaca gctgccctaa atctaagaaa acttcaaccg aaagcagaag ttttactgat
     6481 cgatgaagat cataaagatg gactaggcta tgtttcaaat ggaatcaacc tttatttaaa
     6541 aggaaagata cgtagtttag ctgaagttgc ccataacatg cggactcttc aagaaagtgg
     6601 ggcaaaactg atcaccgaat ggagagtaac tgaacttgat ccagacaaac atcagctcat
     6661 cctcgcatcc aaagaaggaa aaaacgagac cataacctat gataaattaa tcgtagcgac
     6721 aggttcctct cctgtcacct tgtataaaca aattgaagct gaaaatgtct acacctataa
     6781 aaatctagtg caatctaagc aagtacttgc cgctttaaaa gaagcaaaag aagtagtgat
     6841 cttcggtgct ggttacattg gattggaatt agcagatgct ttgagaaata aaggatacat
     6901 tattcatcta gttgattata tgccgaatgt tttatcaaga tatttcgata aggatatgat
     6961 caacagtttt caaaatcagc tgcaaactaa gcaaataaat ttttatccaa atgaattctt
     7021 gatcgattgg aaaaaatcag aagagaaagt agtatccgta caacttctgt ctcaaacaat
     7081 aaaggcagat atggtcattt tttctgccca aactcgtcct aatacgacat tgttaaaaga
     7141 aaaagtggct ttgtatgagg atgagactgt gatagtcaat gaatatctgc agacaagtga
     7201 tccggacatc tatgcgattg gagatatcgt cccagtcagt tttgacaaaa ataaacggca
     7261 tctcttttta cctttagtta ctcgagctgt acatatggca agagcagtag cgctaacttt
     7321 gagtggtcag ccaaccgctt acgacctcag acaaaagata acagcagcag tcattataga
     7381 ctacttttta ggaactgtag ggctgacaga agatgaagcg ccattcttgg aacaaaatac
     7441 cggttcgtgt tcaggagaat ttgatctatt tccacaatac gacgaagaaa acaaaacagt
     7501 aaatgcaaag ctgatctacc atccggatac attagaaata attggcggac agctgataag
     7561 ccaagaattc ttattatcag atttgaacct gcttgcggat atcgtgaaac acaaaactac
     7621 gattccacag ctagcagttg aggattttgg atttctgtct gaatacacct ctcgttttca
     7681 ctacctcaat gagttagctt ttaaagtact agctaagaga gcaaatagca atagagtaga
     7741 taaaagactg tgagaaatat cacggtcttt tattgtgtgg ggatataata aatattaatc
     7801 aatcgagaat aaaaaattca tataatgaaa tagcggaaga attttttgag cataatattc
     7861 gccaaaaatt tatcaagtga taaaattgtt gtataaaatg attatttcag gaggaggagt
     7921 taaatgtttt tagcattaaa tgaaattatg cattcaaagt tacgttatgc gttagttgca
     7981 ggggtgatgt ttttgatcgc ctacctggta ttttttttga ctgggttagc ttatggctta
     8041 gctcaagata atcgaacagc agtcgacaag tgggaggcag attcgattgt gctttcgaaa
     8101 gatgcaaatt caaatctagg gatgtccatg attactaaga agatagcaga agaagtcgaa
     8161 ggtgggaaag tggcgtatct tgcccaaaca cctggagtcg tgactagtaa agacagtaca
     8221 gaagaaggaa aaatcaatgt tagcttcttc ggtatcgata aaaatcaatt catcatgccc
     8281 aatcttgttg aaggaaaagc ttttgataac gatgatgagg cagtaggcga tattagtttg
     8341 aaagaagaat atggtctagc cataggagat acagttaagt tatctggtag tgacaagacg
     8401 tttaaactaa ctggctttac ggatcatgcc aaattcaatg tctcaccagt tctctataca
     8461 accatcaatg cttaccaaga aatccgcttc gaaaaagaag atacaagtga aaatgcacgg
     8521 attaacgcaa tagttgtcag aggtaaaatc agtaatttac ctgaagattt agaacagatc
     8581 aaaatttcta aattcatcaa tgaattacct ggatataatg cgcaagtatt gacttttgga
     8641 tttatgatcg gatttttgat cgttattgcg gctattgtga tcgggatttt catttatgta
     8701 ctgacgatgc aaaagattaa tatctttggt gtaatgaaag cacaagggat cacaggagga
     8761 tttattgcgc gttctgtagt ggcacaaaca ttcattttat catttgttgg tattcttctt
     8821 ggtctattag gaacagtggg aacatccctt gttctacctg atgcggttcc attccaaagc
     8881 aattggctgt tttttggcgt cattagcttg ttgatgttag tagtagctgt gttaggcgca
     8941 ctattttctg ttcggacaat cgtaaaaatc gatccgttga aggcaattgg ataagaagga
     9001 ggaagaacat gaaagcaata gaatttaaag aagtagaaaa aagtttccaa gatggcgacc
     9061 aagtagttaa agcattgaaa gaaacaacca tgagtatcga taaaggggaa tttgttgcaa
     9121 tcatcggtcc ttctggttca ggtaaaagta cttttttgac tttggcaggc ggattgcaga
     9181 cgcctagcag tggctctgta tttatcaatg atcaagaatt cagtaatcaa aaagaaagcg
     9241 aacgcgttaa actacgtttt aaagaaattg gctttatttt gcaagcttcc aatctggttc
     9301 cttttctgac agtaaaaaag cagttattat tagtagataa gattaaacat gaacatcgtc
     9361 aaaaagaagc aaacgaatta tttgagcagc ttggcgtgga taagttgatc aacaagtatc
     9421 cagaagaact atctggtgga gaacggcaaa gggtcgcaat cgctcgtgca ttgtacaatg
     9481 atccgtccat tattctagca gatgaaccaa ctgctagttt ggattcagaa aaggcacgag
     9541 aagtagtcga tatcttggca aaagaatcaa aagacaaaaa taaagcaacg atcatggtta
     9601 ctcacgatac acggctgatt gacaaatgcg atagaatatt tatgatggaa gatggtgtat
     9661 tgaaagaaaa agaataacca aaaagcaggt ggaaaaatgg tccatcgata caacaaagat
     9721 acacagcaaa aaattttgaa agaagcgact gacttgttta tgtccaaggg atatctcggc
     9781 acttcaacaa gagaaatcgc acaaaaagtt gggatcaccc agcccaatct ctatcattat
     9841 ttcggtgata aagaaaaact atatacggca gttttagaaa accacttaaa agatgttgga
     9901 aaagctttga gagaaatcgt tcaaacaagc gaaacgggat ttcaagtaac cttgacaaaa
     9961 atggcgcagt ttttgattga gacacatctg gtcgatttgt ttctgatgct tcacgatctt
    10021 gaaagcaatc tttcaaagga aacaagagat catcttttct ttctatggaa gaaaaattat
    10081 cgtgaacctt ttgaagaaat cttttcagca aaccaatctg tgctaagaaa tgggatttca
    10141 aaagaaatcg cagcaaggca ttttttctta gtgttagcac cttacatcac tcggtcgaaa
    10201 agacctgtgg aagaaccgct aaatgtggcg caattgatcg atttatattt gaatggtgta
    10261 ttaggagaag cgtaaagctg ttatataggg agaaaatagt taggtgaaga agcaagatat
    10321 gacgaagatc gttatatctt gcttctttat ataggtagtt tttcataaat acaaatttgt
    10381 tattctctca tgattatcag ggtatatttt tatttattat gtcggtgttc caggaagtgt
    10441 tttaatttaa taacgaagaa attaattgtt tgtagaatga aggaaactat ttattgggta
    10501 gatgaatcac cacgaatagt caaaaggaga tttcaggata tgccaaaaat gaaaaaaatc
    10561 attttagcag taatgttatt ttctacggtt atatctttta cagccccttt tttgcttact
    10621 taagctgatt ttaagttttg gcccttagtc tggatctacg aggtgagagt caagaatgaa
    10681 aaaaataatt ggagcttttg tatttgcaat cattatcatt attatctgtt ttcaaataga
    10741 tgtttttggt caaaaaaaga tagttggaca aacggtcagc agtacgaaca gtacggttac
    10801 aaagacaaag gaatcatttg atgatacaga acaagagaca ttaatcaaaa tcggaaaaaa
    10861 tgaccgtaca ctatatacag atgactcgct aactacccca cttgcaacta taaacggcgg
    10921 agagctggcg gagtttcttt ctgaaacaaa aaatgcttat cagatcaaga caaatgatgg
    10981 ctatactgga tatttagccc tcgaagatgg aaccaaagtc acaaagaata tacaaacaaa
    11041 accggaagag ctatctgatg cagtgattgt attagatcct gggcatggcg gaaatgatac
    11101 tggggcatta agcaatgatg aacaaacaga agaaaaagat ataacattaa gtacagccat
    11161 aaaagtaaaa aaggcgctag aggatgctgg agcaacggtt tatttgaccc atactacaga
    11221 tgaattagta cagcttggag atatatgcga ctacagtgaa gaaaaaaagg cagatgtctt
    11281 tatcagttta cacgcagact ctacggaata tgcgaatgaa gcaactggaa tcacgacata
    11341 ttattactat ggacaagagg aaacattagc acagacaatt gctgactcct tcactgatct
    11401 gcctctggat tcaagaggaa tctccactgg gaactatcaa gttcttcgag aaaatcttca
    11461 accttctatt ttaatcgaga tgggttatat gaataatgat agtgatttaa aggaattagt
    11521 aacagacagt tatcagcagc agattgctgc aagtttgaca caagcattga ccacttattt
    11581 tcagtaataa ataagcccag ccaaacaaaa atagctcctc atatttttcg tttggccggg
    11641 cttattatcg cagatgcaag cttttaaaca ccgtttaagg aagaggtcgt gagcctgccg
    11701 ttcaactctg agtcacaagg agcaatttca aaaaacagct tctcatgttt gatgactatt
    11761 gtgacttgtg accgaggagt tggcatgaga acaccgttta agaaaaaggt tgtgaaatca
    11821 acgttttgtt ctgagtatta gagaaacaaa cggaaaaata gttcctcata ttttgccgtt
    11881 tgttgagcta ataccgagga tcagatgatt gaacaccgtt tattcggaac aagggactgt
    11941 gacatgactt ttgtcacagt tccattattt ttttagtagc ttcaaagctt tttctgtatt
    12001 ggcaaaatga agtttggcat atttttcaag cataggcatg ccgcctttct ccaatagttt
    12061 tgccgctact tggtcagatt tcgttccagc tcctgacgga agggtgattc cagcttcagc
    12121 tgatgctttg tctaactctt ccaaaaagct ggcacgactg atgatagaag cagcagcaac
    12181 agctaaatga tattgttctc ctttagtaac gaagtacagt ttttcttgta attgattttt
    12241 ttctaaacgc gcatattttt taaaatttgc ttccggcgta aactgatcga tcaaaatcgc
    12301 ttctggtttt tctggctcga ttttttttag cagcaaatgg atcgcttgat tgtgcaaagc
    12361 gactttcatc cgaacggcat tgtattttgg ttggatctca ttgtattttt ctggagataa
    12421 gacaagcagt ttatagggga tggttttttt taagatgtca gcaagctgga tgatttggct
    12481 atcttttaac tcttttgaat ctctaacacc aagtttacgt aattctgcaa gctgatcacg
    12541 tttcacataa gcagcacata ctgttagcgg accgaaatag ctgccatttc cgacctcatc
    12601 actacctaaa acggataatt gactgatatt ttttggcaaa gaagaggctg tttttgctgg
    12661 cttggcttgt ttatcctgtg cctcccccca tttatcagct tctattgctg cattcgtacc
    12721 ttgaaacatc acttttccgg atgtataagc ggtaatggtc gtcccgtctt tttttgcagc
    12781 aaagctagta taaggaatct gtttatttaa caaataagag cgatagtatg ctttcatttg
    12841 actaagttgg tcgtttgttg ctttgataat gacgttgctc ataaaattct cctcgttttt
    12901 atacataaaa ctataccgca actcacgact tttcgttttc taagagattg cgagacatag
    12961 cattttttta aagtttatca tataatagtt aagtatgtga aaaatatttg tggagaacgg
    13021 tgaaagaacc aacttcatgg tacactaaat aaaactttca tcaaatagga ggaaatgatt
    13081 cgtatggcgc acgaaaaaac acgctacaaa gcggtgattg ccaaccaaac atatactatt
    13141 atcggacggg aaaccaagca tcatatggat atcgtaacga agctgatcaa tgaacagtta
    13201 gcagaattga aacaattatc accacaaatg gataatgaac aagcagcaat cttgatggct
    13261 gtcaatgcgc tttcggatca attgaagaaa caagaaagaa tattggagct ggaagaagaa
    13321 acagcagaat taaagaaaaa aatgatcaaa tttacagagc ttgaaaatcg tgtgaaacgc
    13381 attgaagcaa tcgagaacga agctcgggaa gtattgaaag aaaatggtca agcagatcat
    13441 accattaaaa atcatgtgga agcacaacag attttaaacg agaaacgaaa aggacaaatt
    13501 aaacaaaaat cttctaatta agatcctttt atcaaaataa gaaaaattta aaaaagttag
    13561 aagagaaagg aacgtagcat gctgagtttg ctgattttat ttttattgct aattgcgttt
    13621 ttttctggag cacgtcgcgg gtttgctttg caaatcatat tcgcgattgg atatgtattg
    13681 tcatttattg ctgcccagca tttttacaaa ccattagcaa gtcatttgga attatacatt
    13741 ccatacccag ctgtcacccc aacatcaaag ttagcatttt ttgatcaggt atttgccttt
    13801 cacctagatg aagcttttta tgcaggaact gcttttctga ttattttgct aattggctgg
    13861 ctgcttaccc gatttgtggg ggtttttgtc catggattga cgtatgtgcc gatcttgaga
    13921 caggtagact ggattgcagg aggcatcctg tcactaatca tggcttacgt tactatattt
    13981 ttgattttgc agttacttgc ctttgttcca ttagatgtgg tccaaaatca attcggcgag
    14041 catagtttcg ctcgttttat cgttgagaga acgccatttc ttaccaacaa gatgtatgag
    14101 ctttgggtaa cgaatatttt gaattaagga aaatagtgct ggaaaatatt tcgttttttg
    14161 tacagagtag tttatttaag aaggctgcgt agcgtatgtc cggcacagct cttttttcat
    14221 agtgaaagat aaggtgataa aatgaataac cgaatccttg aaacattgga atttgaaaaa
    14281 gtcaaacaga tggtcagaca atttgtagtg actgcacaag gaaaagaaga actggcagaa
    14341 ttggtaccag tgagtgagaa acaaacgatc acaaactggc ttcaagaaac tgaggatgga
    14401 ttgaaagtgc aacgtctgcg aggcgggatc cctataccta aaattgaaaa tatccgtccc
    14461 catatgaaac ggattgagat cggagcagac ttgaatggag tggagcttgc acaagtttcc
    14521 agagtattgt ctacgacaag cgaattgaat cgtttcattg atgatctttc tgacagtgaa
    14581 atcgaatttg cacgtttgta tatgtgggca gatcagttag tcacgatccc tgttttgagc
    14641 cgccgtttaa aggaagcaat cgatgaagac ggacgcgtga ctgatgacgc ttctcctgag
    14701 ttaaagagca taagacagaa cattcggcga agtgaacaag ctgttcgtga acagttagat
    14761 gggatcgtcc gtgggaaaaa tgcaaagtat ttaagtgatg cgatcatcac catgcgaaat
    14821 gaccgctacg ttatcccagt caaacaagaa taccgcggtg tatttggcgg tgtagtccac
    14881 gatcaaagtg cttcaggtca gactttattt attgaaccaa aacaagtggt ggatttgaat
    14941 aatcgtttgc gtcaatacca aatcgctgaa cgaaatgaga ttcaacgtat tttaagtgaa
    15001 ctttctgctg aacttgttcc ccatcgtcaa gaaatcatcc acaatactta tgtgattggt
    15061 aaaatggatc tgatgaatgc aaaagcacga tttggtaaag aagtaaaagc catcgtgccg
    15121 ggaatcagtg aagacaatca tgtcgtcttg aaacaagcaa gacatccact gatcgatcag
    15181 gaaaaagtag tttctaatga catcacaatc ggaaaagact atcaagccat cgtcattaca
    15241 ggacctaaca caggtgggaa aacgatcacg ttgaagactt taggtctgtt acaactgatg
    15301 gggcaagcag gattaccgat tcctgcaggt gaagaaagtc aaatcggtat ttttgaggaa
    15361 gtatttgcgg atataggaga cgaacagtcg attgagcaaa gtctatcgac cttttcttct
    15421 catatgacga acactgtaga tattttatca aaagtcaatg aaaaaagtct ggtattattt
    15481 gacgagctcg gtgcaggaac agatccgcaa gaaggtgctg ctctagcaat cgcaatctta
    15541 gatgatcttg gtaaaaagtc tgcttatgtg atggcaacaa cgcattatcc tgaattgaaa
    15601 gtttatggat ataatcgggc aaatacgatt aatgccagca tggagtttga tgtggataca
    15661 ttaagtccaa cgtatcgttt gctgattggc gttcctggac gaagcaatgc gtttgaaatc
    15721 tctagccgat taggtcttga tacagaagtt attgatgaag cgaagcagtt gatgaatgat
    15781 gagagccaag atttaaacga aatgatcaca gatttagaga atcgccggaa aatggcagag
    15841 accgaatatc tggaaatgcg tcattttgtt tctgaggcac aagaacttca cgatgatttg
    15901 aaagaagctt acagctattt ctttgaagaa cgtgaaaaag aaatggaaaa agcaaagaaa
    15961 aaagcaaatg aagtcgtgtc agaggcggaa gaaaaagcag aaaaaatcat tgctgatatt
    16021 cgtaaaatgc aacagcagat tgggcaagga aatgtgaaag agcatcagtt gatcgatgca
    16081 aagacccaat tagcaaatct acatcaagaa gaaactttga agaaaaataa agtattgaag
    16141 aaggcgaaag aacaaaaaac gttgaaaccg ggagacgaag tgttggttac gacttacggc
    16201 caaagaggga cgcttttacg taaaaacggg aatcagtggc aagtagaaat cggtatatta
    16261 aaaatgaatg tgtccgaaga cgagctgacg cctgttgctc ctcaaaaaga gccgacacaa
    16321 cgagttatcc atgctgtacg atctgaatct agtagtcacg tgccgaatca attggacctt
    16381 cgaggaaaac gatacgaaga agcgctaagt gaggtagatc aatatttgga ttctgccatt
    16441 ctagctggtt atcctcaagt gactattgtc cacggaaaag gaacaggcgc acttcgcaag
    16501 ggaattactg attatcttaa aaaccatcgg agcgtcaaaa gctttgagtt tgcaccggca
    16561 aaccaaggcg gaaatggtgc gacaattgtt aaatttaagt aaagcttact aaaggtaagc
    16621 agatggttcg ctatccaagt atagaaatgc tatactagtc atagatttta aaaatggagg
    16681 tctttgatat gtcacaagta attacagata agacatttaa tgaagaaaca gataaaggac
    16741 ttgtattgat tgatttttgg gcaacttggt gtggtccatg tcgtatgcaa gcaccgattt
    16801 tggatcagtt ggaacaagaa tatgatgaag aagaattcag aattgctaaa atggatgtgg
    16861 atgaaaatcc agaaactcct caacaattcg gtatcatgag cattccaaca ttaatgttga
    16921 aaaaagatgg tcaagtagta gaaaaagctg ttggtgttca ttcaaaagaa caactacgtc
    16981 aaatgatcga tcaatattta taaaaactta cagcaaaaat aagctgaggg tgggactgaa
    17041 tccagttccg tcctcggttt ttttgcggtt gagttaaggt tattcaaatt aatatttttt
    17101 gagtataatt acgttgtcag gctggattgt ttttttgaca gacatgctat aataacttta
    17161 attgaatatg aaggggagta ccagatgaac gaacgaatca aaaacaaatt agctttactt
    17221 cctgatcagc ccggctgtta cttgatgaaa gataaaaatg gaacgatcat ttatgtcggc
    17281 aaagccaaaa tattaaaaaa tcgtgtccgc tcatatttta ctggtagcca taatacgaaa
    17341 acggaacggc ttgttagtga aatcgaagac tttgaataca tcgttacaga atcgaatatc
    17401 gaagcattgc tcttagagat caatctgata aagaaaaatg atcctaaata caacattatg
    17461 ttaaaggatg ataaaaccta tcctttcctt aagataacga atgaaaaata tccccgtttg
    17521 gtgattactc gtaaggtact aaaagacaaa gcactgtatt ttggaccata tcccgatgtc
    17581 ggtgcggcga atgagacaaa gaagatcctc gatcgattat ttcctctgag aaaatgcaaa
    17641 cctagtcaga cgaaggagcc ttgtctttac tatcatttgg gacaatgcct gtgtccttat
    17701 tatttcgacg tagatccgaa agtctatacg aaaatcgttg atgaagtgaa aaacttttta
    17761 aacggaggac acgaaaaaat cgagtcagag atccatcaga aaatggaaaa agctgctgaa
    17821 aacatggagt ttgaaaaagc tgcagaatac cgagaccaga tccgtgccat tgagacaatc
    17881 atgactcgcc aaaaaatgac aaatactgat ttactggatc gagatgtatt tggttatgcg
    17941 attgataaag gatggatgtg tgtccaagtg tttttcgtaa gacaaggaaa gctaattgaa
    18001 cgagatgttt caatgtttcc tttctataac gaagcagaag aagatttctt gacttacctc
    18061 ggtcagtttt atcaggaaaa tgagcatttc attcctaaag aagtcttgat tcctgatacg
    18121 atcgacaagc ccagtgtaga agctttgtta gctacgaaag tgctgcaacc aaaacgagga
    18181 gaaaagaaaa aattagttga attggcgagt aagaatgcct cagttgcttt gaatgaacgg
    18241 tttgatctga ttgccagaaa acaggaacgg acgatcggag cagttgaacg tttaggaaac
    18301 gcgatgaata tcccgacccc aatacgtatc gagtcttttg ataactctaa tatcatgggg
    18361 acgaatcctg tggctgcgat ggtcgtattc attgatggaa aaccggcaag aaaagaatat
    18421 cggaaatata aaataaaaac agtcaacgga ccggatgatt atgcatcaat gagagaagtc
    18481 atctatcgca gatattcgcg agtgattcgc gaagggttgc ctttacctga tttgatcttg
    18541 atcgatggag gaaaaggaca agtagatgtg gcaaaagatg tcttagaaaa tcaattagga
    18601 atcgatattc ctattgctgg catggtaaaa aacgataaac ataaaacaaa tgagttgcta
    18661 ttcggtacag atttggctgt agtaccgctt gagcgaaatt caccagagtt tttcttactc
    18721 cagcgaatcc aagatgaagt ccatcgattc gcaatcactt tccatcggca gctacgcagt
    18781 aaaaacagtt ttgcttcccg attagatgaa attgaagggt taggaccaaa acgaaaaaaa
    18841 atgctgctta aagagttcaa atcgttgaaa aatatcacag cagccacgac agaagaatta
    18901 caagaaatcg gactgccgaa aaatgtcgca caaaacgtat ttgataaatt acatcaggaa
    18961 tgaggaaagg gcactttaca aagaaagtaa agtgtcctat cattttatgt acaacaaaaa
    19021 gagcgtttac gttttgttgg taaataataa atcgcttacg tctggtgtct aaggatatat
    19081 gtgatttctt gaagaaggag tgaagaaatg ttagaagtca aggatcttgt taaaactttt
    19141 gggaactaca cagctgtcga tcatgtctct ttccaaatcc ccgatggaaa aatcatgggg
    19201 ctaattggcc aaaacggggc tgggaagaca acgacttttc gtttgatctt ggattttttg
    19261 acacaagacc aaggagaagt gttatggaat ggccatcatc ttggggagaa agattatgat
    19321 gtcatcggtt atcttccgga ggaacgggga ctttatccga aagtaacgat tcaagaccaa
    19381 ctgctttatt ttgcagaact tagagggaaa tcaagaaaag agattgaacc aaaaatcgac
    19441 ttttggatgg aaaaatttca ggtaaaaggg aaaaagacgg ataaagtaaa atctttgtct
    19501 aaaggaaatc agcaaaaagt ccagctgatc gccacgttaa tccatgaacc taaattgatc
    19561 attttggatg agccattcag cgggttagat ccggtaaatg ctgaattgct aaaagatgga
    19621 atattggaat tgaaaaaaca tggttcatgt gtcatttttt ctagccacaa tatggataat
    19681 gtagaaaaaa tctgcgatca tttgatcatg ttgcgaaacg gaaaaatggt tttgaatgga
    19741 aaagtacatg agattcgtga atcatttggc cgtacgaagt tattcttgga atctggttta
    19801 agccaacagg aagtagaaga aatcgaaggc gtgaaaaaag tgatccttca tgaagacaat
    19861 acgttagaga ttaccttaga agatcctgaa gctgggaaag aaatctttac tcgtgcgact
    19921 cagttcggct acattcctat gtttaaccag caaccgccaa ctttggaaga gattttcaaa
    19981 ttgaaagcag gtgaaatcga tgcgtaagtt ttggattatt accaaagatg tctatttaaa
    20041 aaatgttaag tcgatttctt tcttgatcat gatattagtc ccttttatca tgctgggtat
    20101 catttatgta gcaggaaact ttgctcaaca aaatagtgat gtcaataaaa tcggcgtatt
    20161 ggctgataat gagcaaatca gtcagcaaat gagccaagtc aaaacagatg attttgagtt
    20221 caaagcagtt gattctgaag aaaaagcaca aaaagagctt tcggaagaaa aaatcgatgc
    20281 gtatttagta gtctcaactg agaatgataa gataaatggg atgctttata gcgaaaattc
    20341 attaggacaa agtacacaac tactgataca acaacaactg actggcttgc aatcgatgct
    20401 tcgagcgagt caattaggca tttcaccaga agaagtagct agcttgagcc aacaagcaag
    20461 tttgactcga caaaaagtca attttgattc aaaaggaaaa atgacagtcg gagaagataa
    20521 ctcgacagtc caatacgtcg taagttatgt agcaacgatt gtcttgttca ttattatttt
    20581 gacgtatgcg cagatcattg cacaagagat cgcttctgaa aaaggcacgc ggatcatgga
    20641 agtgatcctg tccagtacga ctgcacaaaa gcatttttac ggaaaattaa caggtgtttt
    20701 acttgttgca ttaacgcaaa tggcattata cggtattatt tttggtatag gatacagtca
    20761 attcaaagat atggaaatgg tcaaaaatat attagacggt atctcattgg ataacttgat
    20821 tggaccattc ttgtggtatt ctcttctatt catgatcttt ggcattttga ttttttctgt
    20881 tttagcagct ttatgtggct ctttggtcaa caaagcagaa gatacagcaa aagcaatttt
    20941 gccagtgact tatctatctc taggcggata catgcttgga ttgatactag gagcttcaga
    21001 tccaaacaat atcgttattc ggatcacttc gtatattcca ttcttatctt catatattat
    21061 gccgattcgc ttagcaaatg agacagtcgg tatgggtgga gcattgattt ccttgttggt
    21121 acttgtagcc gtaacattct tattgatgat cttgtctgca aacatgtaca aatcgaatgt
    21181 actcgtttat agcgaaggcg gattatggag ttcattgaaa caatcgattt caattatgag
    21241 gaatgaacga aaaaaagcat aaaacaatcc taaaatacag aaggaagctg gacatctatt
    21301 gttcccagct tctttttgta tagacctatt ttatttattt tactatattg gatatatatt
    21361 cattgaaaat agtgtataac aactttataa tattgagtat accaattttt ggaggcgttt
    21421 taatggaccg ttatttagat ttactttcag aaaaattccc ctcaacggag gatgtcatca
    21481 cggaaatcat caatctcgaa gcaattttgc agcttccaaa aggaacagag ttatttttga
    21541 gtgatataca tggcgaattt cctgcttttg atcatattct gcgtatcggt tcaggaaatc
    21601 ttaaagaaaa gatcaaagac cttttttctg aacaaatgac ggaaacggat atcagccaat
    21661 tcactatttt tacggcttat ccagaatatg cattaacgac tgattggtac aaagaacaag
    21721 ataaatcgca gctgatccat catttgatcg atcttttacg gtttacgaca gtcaaatata
    21781 cccggtcaaa agttcgaaaa ggattgccga aagaatatag ctatatcatt gaggaactct
    21841 tgtatatcga tgaccgtatc aatggaaaaa aagactatgt aaaaaaaatc attgaacaac
    21901 ttgttttgat gaaggaagaa gaaaaatttt taacgaaact tgcacagacg atccaaaaat
    21961 ctgtcatcga tcatttgcat atcgttggag atatttttga ccgaggaact caagcagcca
    22021 aagtgatgga tcgaatcatg gatttttctt ctgtagatat ccaatgggga aatcatgata
    22081 ttttgtggat tggtgcgtat tgcggctctg aggcatgttt actgacactt ttacggattg
    22141 cagcacgcta taattattta tttgaattag agaaagaata tgggttgaat ttacgtccat
    22201 tgttttcttt tgctcatcaa acttatcaga agaatccagt atttgcgcct aaaaacagta
    22261 aaaatctatc cgaaagagag caagaagaat tagaaaaaat ccatcaggca ctttctatcc
    22321 ttcaattcaa atcagaacat cagttattgg atcgtcgacc tgaatttaaa atggacgatc
    22381 gtaaattgct ggaaaaaatc gactatgaag catcaacgat tgatttagaa ggtcagctct
    22441 atgagttgaa aggaacttgt tttcaaacga tccagccaga tgatccaaaa aaattcttgg
    22501 aagaggaaca aaaagtgatt gatagtttga tgtattcatt ccagcactct ttgagaatgc
    22561 aaaaacatat gacgtttttg atcgaaaaag ggggaatgta tctcacgaac aatcagcatg
    22621 tgctgtttca tggctgtata cctgtagacg agaagggaca gctcttagca tttgaattag
    22681 accaatctta tcgcggaaaa gaactgctgg gcttttttga aaaacagata actgaaagcg
    22741 caaaagatct gactgcaaaa gaagatttag caaccgattt gatttggtat gcgtggagtg
    22801 ggccattttc gcctttattc ggcaagagta aaatggcgac ttttgaacgt tattttctca
    22861 cagagcctca tacgcacgtc gagaaaagca atccttatta tcacttgcga gatgaagagt
    22921 ggttcagtga aaaaatttta gcagaattcg acacaaaaga agaagggtca gcaatcatta
    22981 atgggcacac gccagtaaaa gtaaaaaaag gggagtcacc gatcaaagca aatggaaaag
    23041 tatttgtcat tgacggaggt ttatccaaag cttatcaaaa aacgacagga attgccggtt
    23101 attcactatt atgcaattct tatggtttcc aaatcgtgac acattatccg tttttgccta
    23161 ttgaacaaca atttgcaaaa aaatccgacc aaacaaatgt gaaaaaagta atcgaacagc
    23221 aactaccacg caaactcaat cgtgatacaa caaaaggtat ggaactgcag cagcagatta
    23281 cccagctcaa aaggctgttg gactatcgaa aggacgattg agaagaattc cagtgaacat
    23341 tgttccatag actggagact gagacaaaag tcgtgtcgca gtctcttttt ccggataaac
    23401 ggtgttcttc tgccaactcc tcggtcacaa gtcacactat tcaacaaaca tgaaaagctg
    23461 ttttttgaaa ttgctccttg tgactcagag ttgaacggca ggctcacgac ctcttggtat
    23521 aaacggtgtt caaaagccag tttctcggta ttaagccaaa tttatgcaaa aatgtgaaaa
    23581 gccattttca caaaattttt cttaatactc gaaactaaac agctttttca caaccccctc
    23641 agaaagtcta ttaaaattca ttcacaaaga aatcgaataa gcgctgttca gatggatgta
    23701 cacggtgggt aagttccgga tgccattgaa caccgaggat tttatgcata tcatctttgc
    23761 tttgaaccgc ttcaacgagt ccatcgttag aaaaagcgat ggcttttaat aaaggtgaaa
    23821 gatctttgac tgcctgatga tggtaagaat tcacaaaata tggatcgggg agaaggttgc
    23881 ttaacaaact gtctgaaaca atcttgactt cgtgagtcgt aaattgcggg gcagtgggct
    23941 gttgttcatg ttttactgac cactttggat ataatgaaag atcttgataa agtgtacctt
    24001 ccaaaacgac attcaatagt tggagtcccc ggcagactgc aaaaattggt tttctttgtt
    24061 tcaatgcttc caagatcagt gcctgttcaa attggtctcg ttgaatattt gtttccgtta
    24121 gctttggatg aggatcttcc atgtaaagtt gtggactgac atcttgacca cctgcaagaa
    24181 taagtttgtc gatttgtcca atcagttgag gagctgaatc tggagacatg actggcagaa
    24241 taagaggcaa tccttgagca tctaaaactg catccacgaa tccttgcggt gtatagctca
    24301 cttgatttcc ttggaaagta tctgttgctc gaatcagttg atttccggca atgccgatga
    24361 ttggtttcat ttgtattccc cctaaagtag acttattgta acaaggattt aaaaaaaatt
    24421 aaactatgta agacttgccc ctatacttat ctgttcttgc tgtgttacta tctgtaaaga
    24481 gaaatttcgt gtgaaattca tgacgatagt tgaaaatatt gcttaatttg ttataataaa
    24541 aagtaagcag aaataaaaag gttgggcgta agcttcaagg atctagttct tcaaggggtg
    24601 agaaggacat tttattgaag gggcctgcct atactaagtt atctttagag gtacatactt
    24661 tcaatgaaaa aagaaagcat gtacctcttt tttaaatcga aaggaagtga agcaagtgtt
    24721 agaagctttg gaacaaatcc gaaaagcaga agaagaaaat gaaaagcgtg ctcaaacact
    24781 gcggcagcag ctgaagatct atgcaacaga aaaagagcag gaattggaaa cgatccaaac
    24841 aaactatcga caacaactaa aacagttggt ggaagaaaaa gaacaatttg aaatacaaga
    24901 attagaaaaa gaaaaaatga aattgaaagc agaagcagac aaggtgcaag caactttgaa
    24961 agatcaatat caaaagcatc agagtcaagc gatcggtgcg atcattgaaa gggtgaaaga
    25021 aacttatggc cgtcactaag atggaaaaag tgaccctcat ttcagataaa agaaatcagg
    25081 agaggatttt acaagcagta caaggaatcc aaaacgttga aatccgggat ctgtatcaaa
    25141 atagaacaaa caaccagtgg gtggagaagt attttccaga taccacgatt attgataaag
    25201 aagcaaaatt aagcgcttta ggtaatcggt tgaaagacat ccaagaagct atccaattca
    25261 tacaacacca cggcgatagc cgtcaaaaga aactccattt gaaacgtcaa gaactttcct
    25321 tacaagattt ggaagccaat tattccgaag aaaatttcat aaataaattg aaagaagtcc
    25381 ttgatttaaa agaaaagtgg gaacaactaa ctgaagaacg tgatcgttta gaagaagagg
    25441 aagaatggct tcttcattgg caacagctgg atattgctcc aagtatgtat gcaagtaaga
    25501 cgaccatttt tgagatgggg actgtgagtg cagcaaattt tgaaagtttc aaggaagaac
    25561 tgagtaagct tgatgacgtt tatatggaag aaatagatta tacgccaaaa caagtttatc
    25621 tttcgtatgt tgctttaaaa aaatcagttg ctgttataga agaaattgct gggaaatacg
    25681 ggttcaataa agaaacgtat ccttatgaac aaaatcctaa agaaaaactg caagagacca
    25741 agcagcaatt atccattgtt cacgagcagc aaaagaagat aacgacagcg ttaggtcagt
    25801 gcagtggcta tatccaagaa tttgaatggg tagaagaagt cacacttgcc gttgcagaac
    25861 gagaaaaaat aaaagaacgg tttatccatg cgacttatct gatcgttttg caaggttggg
    25921 tagatgcaga agaaaaacag aatttgctgc atgtgttaaa cgaaaccgta tcagaagaag
    25981 atatatacgt cagtttcgaa acaccaaact cagaagagat tcagcaggaa gtccctacta
    26041 aattgaaaaa ccatccgctt gtcgaacctt ttgaattgct gactgaaatg tacagtctgc
    26101 caaaatatga agaagtagat ccaacacctt ggatgacacc attttatctt gtcttcttcg
    26161 ggatgatggt cgcagatgtt ggttatggtt tgctgatgct cattgggaca atactagctc
    26221 aaaaactact tgttctacca cgcgggatga aacgtttcgt aaaattcttt gagattctct
    26281 cgataccatc gatcatctgg ggattgatct acagttcatt tttcggacag tcattaccaa
    26341 aagaactgtt tggcatccgc ttgcctttcc caatcctatc tacgacggat gacgtcaata
    26401 cgattttgat tttatccgtg attttcggtc tgatacagat tttggttgga ttatttgtgg
    26461 cagcaaagga aaatatcagg agaaaagatt acttgagtgc tgtcagtgat ggatttgcct
    26521 ggcaagggat cctaattggg atcgttattg cgttggttgg tgccatgttg ataaaaaata
    26581 cagcatttgt ttaccttggc gctgggctat cgatcattgc tgccttatgt atcttgatcg
    26641 ttccgattat ccaaacgccg tctaaagtca aaggtgctgc caaaggtgcg tataatcttt
    26701 acggactgac cggctatatc ggtgatttag tcagttatac acgtttgatg gcattgggta
    26761 tttcaggcgg aagtattgga gcggcattca atatgctagt tgctttcatg ccgccagctg
    26821 ctcgattcag tgtagggatc cttttgatca tcgctttaca cgcactgaat atgtttttga
    26881 cactgctaag tgcctatgtc catggcgcac gattgcagta tgtcgaattt tttgggaagt
    26941 tttatacagg aggcggacgt gcctttgatc cgctgaaaac ggcggaaaaa tacgtcaaca
    27001 tcaatcacaa gaaaaaaaac aataaataat tggaggattt ttatataatg atggattact
    27061 taattagtca aaatggtgga atggtatttg cggtattagc gatggcaaca gcgacgattt
    27121 tttcagggat cggttcagct aaaggtgttg gaatgacagg tgaggcagca gcagcattga
    27181 caacaagtca acccgaaaaa ttcgggcagg ctctgattct gcaattgctt ccaggcacgc
    27241 aaggtttgta tggattcgtt attgcctttt tgatttttat caacttagga aatgacatgt
    27301 cagttgtaca aggactgaac tttctaggtg cttctctgcc gattgctttt acaggcttgt
    27361 tttcaggtat tgcccaagga aaagtcgcag cggcaggtat tcaaatttta gcgaaaaaac
    27421 ctgaacatgc tacaaaagga atcatttttg ctgcgatggt tgaaacatac gcgattttag
    27481 gtttcgttat ttccttccta ttagtgttga atgcctaagc ataaaggagg aaaagcagat
    27541 gaacgccatt gaaaaaatca tctctcagat gaacgaagca gcagagcagg aaagagcggc
    27601 gttagaacaa gaagagcgaa tgaagatcga tcaaaacttt gaacaaaaac gtacgcaagt
    27661 tgaaacagaa catcaaaaac aaaaagaaaa acaaatcgaa ttactcgaaa aaaaataccg
    27721 tcagctaagg aatcgccagc aagtagaagt acgacaagaa aatttgaatg cgaagcagga
    27781 atttttaaga cgattgtttg cagatgcggt aactgaaatg gaaaattggg atgaatctga
    27841 acaaatccag tttatcaaaa atgcattgta ttcattacct ttgacaggaa aagtagcatt
    27901 cattgctgga gaaaaatcag cagcctatct ttctcagacg ttgttggatg aatggaacaa
    27961 tgaacttccc tttatgatgg ttttaagtga tgaaactgtt gctgatcaag cgggttttct
    28021 gataaacgat caaggagttc agtataattt tcttttcagc agccttgtac aagatatcca
    28081 aggaacgatg agttttgaga ttgccaatca attattcgaa taaggaggga tcagtgtatg
    28141 gaataccacg aactaaatcc cttgattcgc ggaagagagc ttgaactttt gtccaatgag
    28201 acatttgaac ggatgattca aacaaattct gtcgaagcac ttggtgaaat attgaaatcc
    28261 acgatttaca gtccatatat ttatgacgga tatgaatatg acttcgaaca gaatctttta
    28321 aaggagcaga gccgtctatt tcgctggtta aaggaatcag caccggagcc tgaaatcgtt
    28381 tggatctata cgatgcgtta tactttccat aatctgaagg ttttgacaaa agctgagatg
    28441 acaaatcaaa atctggacca tttgtatatc gacgatggat tttattcatt agaaaccttg
    28501 aaggatgcca ttcatacgca agtttcaaat gaacttcctg aaagcattat ggacagtata
    28561 cgagaagtac gtgattattt tgaagagtct accattcttc agggaattga cgtgatttat
    28621 gatcgacagt ttttgacaga gcagcgacgg cttgccgata agctaggata tcaagaattg
    28681 ctgacagaag tcattgcttt tattgacttg accaatatca caacgatggc tcgaggaata
    28741 ttgcagaaaa gaacatatgg gttcatgacg acggtacttt ccagctcggg aagtatcgaa
    28801 aaagaagtat ttttgaactt tgtagataaa gatatggaag attacacgaa ttttctatta
    28861 gagacagatt atgctgattt tctgcgccct gtcatccgtg agggaaatat tgatctcgta
    28921 aagcttgaac agttgaaaga tgattatcta agttcattgt atcaagaagc acaaacccag
    28981 gctttcggac cactgccact actagccttt ttgaacgcaa aagaggtaga aagcaaaaac
    29041 cttcgtttac tggttatcgg caaaagaagc catttcgaat cagaaacaat cagaaagcgg
    29101 gtgagacaag tctatgacgc ataagatcgg tgtagttggc gacaaagatt ctgttttgcc
    29161 attcaaattg tttggctttg atgttcgtta tggtacaacc aagcaaaccg ttcgtcaggc
    29221 aattgaagaa atggcaaaga atgagtatgg cgtgatttat gtcacagagc aatgtgcagc
    29281 attgagccca gaaacgatcg aacgttacaa ggaacaaatg atacctgcta tcgtattgat
    29341 tcccaatcat caaggatcat tagggatagg gctggaagaa attcaaaaaa acgtagaaaa
    29401 agcagtaggt caaaatatct tatagtatga aaaggagata gaaattttgc aaattggaaa
    29461 aatcataaaa gtctccggac ctcttgtaat ggctgagaac atgtctgatg ccagtatcca
    29521 agacatgtgt ctagtgggag atctaggagt tatcggagaa attatcgaga tgcgtggcga
    29581 tgtggcgtct attcaagtat atgaagagac ttctggaatt ggtccaggcg aaccggttcg
    29641 ctctactggt gaagctttat ctgttgaatt aggaccaggg atcatttcac aaatgtttga
    29701 cggaatccaa cggccattag atacctttat ggaaatcaca caaagtaatt tcttagggcg
    29761 cggagttcaa ttgcccgcat tggaccatga gaaaaaatgg tggttcgaac caacagtaga
    29821 agccggagaa acggtgagtg ctggagatgt tatcgggatc gtagaagaaa caaaagttat
    29881 aaaacataaa atcatggtgc caaatgggat aaaaggaacg atcaaaacaa tcgaaaaagg
    29941 ttcattcact attgatgaaa cagtatgtgt cattgaaacc gaaaatggtg acaaaaattt
    30001 gacgatgctt caaaaatggc cagtaagacg tagtcggcca atcaaagaaa aattaaaccc
    30061 ggatgcaccc atgatcactg gacagcgagt gattgataca ttcttcccag tgacaaaagg
    30121 aggagcagca gctgtacctg gtccttttgg tgcagggaaa acagtcgttc agcatcaaat
    30181 tgcaaaatgg gccgatgtgg acatggttgt ctatgtggga tgtggcgagc gtggaaatga
    30241 gatgacggat gttttaaatg aattccctga attgattgac cctaatacag gagaatcgtt
    30301 gatggaacgt acggtattga ttgctaatac atcaaacatg ccagtagcag ctcgagaagc
    30361 ttctatctat acgggaatca caattgcgga atatttccgt gacatgggtt atgacgttgc
    30421 tatcatggca gactccactt cacgatgggc agaagcactt cgtgagatga gcggacgttt
    30481 ggaagaaatg cctggtgatg aaggttatcc agcttatctt ggttcacggc ttgcggaata
    30541 ctatgaacga tctggaagag tcattgcatt aggatcagaa ggtcgcgaag gaagtataac
    30601 cgcaatcagt gctgtatccc cgtctggagg ggatatttcg gaaccagtca cacaaaatac
    30661 attgcgggtc gtaaaagtat tctggggtct tgattccagt ttagcccaaa aaagacattt
    30721 tccttcgatc gattggatac aaagctattc tctttattca acagaagtag ggaagtatat
    30781 ggatcatatc cttcaagctg actgggcatc catggtcacc gagggcatgc gtattttgca
    30841 ggaagaacag cagctgaatg aaatcgtgcg tttggtaggg attgattccc tttcagataa
    30901 tgaccgtctg acattagaag tggcaaaatc cattcgtgaa gattatttgc agcaaaatgc
    30961 ttttgatgat gtcgatacat tcacttcaag agagaaacaa ttcaaaatgt tgaagatgat
    31021 cttgaccttt ggtgaagaag gacgccgtgc gttgtcgtta ggtgcttatt taagtgagat
    31081 catggacggt accgtatcga ttcgtgaaag gatcggacga agcaaatata tcccggaaac
    31141 agaattagaa aaactagatc aaattattgg tgaaatcaag caaacgatgc aaacgatcgt
    31201 ttcagaagga ggcatgagca atgattaaag aatatcgtac gatcggtgaa gtcgtcggtc
    31261 cattgatggc ggttgaaaaa gttgctggtg tcaaatatga agaattaatc gaagtccgta
    31321 tgcaaaatgg cgagattcgt cgtggacaag tattggaagt ccaagaagat aaagcaatgg
    31381 tccaaatatt cgaaggaaca agtggtatca atttacgtga ctcttctgta cgatttttag
    31441 gccatccttt agaactaggt gtatcggaag acatgatcgg tcgagtattc gatggtttgg
    31501 gacgaccgaa agataacgga ccagagatcc tgcctgaaaa gcatttggat attaacggag
    31561 aagtaatcaa tccagtagct cgggattatc cagatgagtt tatccaaaca ggtatctctg
    31621 caatcgatca tttgaataca ttagttcgtg ggcaaaaatt accagtattt tctggctctg
    31681 gtcttcctca taaagaatta gctgctcaga tcgcgcgaca agcaacggta ctcgattcat
    31741 cagatgattt cgccgtagtc tttgctgcta ttggaatcac ttttgaagaa gctgaatttt
    31801 tcatggaaga ttttcgtcaa acgggcgcaa tcgaccgttc tgtcatgttt atgaatttag
    31861 caaacgaccc tgcaatcgaa cgtatcgcta ctcctcgtat ggctttgact gctgcagaat
    31921 atcttgctta tgaaaaggga atgcatgttt tggttatcat gacagacatg accaactatg
    31981 cagaggcatt gcgagagatt tctgcagcac ggcgagaagt tccaggaaga agaggatatc
    32041 ctgggtatct ttacacgaac ttagctactt tattcgaacg agcaggaaga atccgcggac
    32101 taaaaggatc ggttactcaa attccgattc taacaatgcc agaagacgat aaaactcatc
    32161 caatccctga cttgactggt tatattacag aaggacagat catcttgact agagagcttt
    32221 acaagagtgg gattcagcca ccaattgatg tactcccgtc tctttcgcgg ttaaaagata
    32281 agggaactgg acccggaaag acaagagaag accatgcagc tacgatgaat cagctttttg
    32341 cagcctatgc acaaggaaaa caggcaaaag aattagccgt agttttaggt gaatctgctt
    32401 tatctgatgt agacaagatc tatgcgaagt ttgctgagcg gtttgaaaaa gaatatgtca
    32461 atcaaggatt ctacacgaac cgttcgatta ctgaaacact tgatctaggg tgggaactgc
    32521 tatcgatgtt gccaagaacc gaattaaaac gaatcaaaga cgacatgctg gacaaatatc
    32581 tgccagaagg gaagtgagtt ctgatggcac gattgaatgt gaatccgacc cgcatggaat
    32641 tgactcgatt gaaaaaacag ttgacaactg ccacaagagg gcataaatta ttaaaagata
    32701 agcaagatga actgatgcgt caattcatcc tgttgattcg aaagaacaac cagctgcgtc
    32761 aagaaatgga agagtctatg acagaagcaa tgtctgattt tgtattggca aatgcttcga
    32821 tcacggaacc tttcatcgaa gaattatttg ttttgccggc ggaaaacgtt gatttgtcta
    32881 tcgtagacaa aaatatcatg agtgtaaaag tacctgtgat gaattttgaa tatgatgaac
    32941 agctgacaga cacacctttg gaatacgggt atttgaattc cagtgccgaa ctggatcggt
    33001 caatcgatcg gtttactacc ctgcttccaa aacttttgga actgacagaa atcgaaaaaa
    33061 cttgtcaact gatggcgagt gaaatcgaaa agacacgtcg gcgagtcaat gcattagaat
    33121 atatgacgat ccctcaatta gaagaaacga tctattatat tcgtatgaag ctggaagaaa
    33181 acgagcgcgc agaagtaaca aggttgatca aagtaaaaaa tatgggtacc actgactaag
    33241 tggtatcttt ttttaaaaga ggaaaacgat gattaaacaa agcaaacaaa taaagaaacg
    33301 tttgccggct gttcagcttc tcgcattagg attttttctc ctgattttag ttggcggcgg
    33361 cctacttacc ctaccatttt ttagtaatag tgggcatggg acaaatttta tcgatgcgct
    33421 tttcactgca acttctgctg tctgtgtaac gggattgaca acattgaata cagcagagca
    33481 ttggaacagt gctggtcaat ttttgatcat gcttttgatt gagatcggcg gtcttggttt
    33541 tatgatggtt ccgattctat gctttgcatt gataaagaag aaagtcagtc tcagcacacg
    33601 tattatatta aaagaagcgc tgaatctaga agaagtatca ggtgtgatga agctcatgct
    33661 ttacatccta aaattggcct ttgtgatcca attgattggt acggttgctt tatcttttgt
    33721 atttgtgcct gaatttggct ggttgaaagg tatctggtac agtttgttcc atgcaatctc
    33781 tagtttttgt aatgcagggt ttgatttgtt aggagacagt ttagccaatc accagcaaaa
    33841 tgtttatttg atcatggtgg tatctgcttt gatcatttct ggtgggttag gcttcatcgt
    33901 atggcgtgat ttactggaat atcatcagaa aaagaagatg acgattcatt caaaaatcgc
    33961 attaaccgtt acaggtaccc ttttattagg cggattcgtt gtgttctttt tcacagagcg
    34021 caatggggca acgctagtgg aagggaatat gtttcaacga ttggcaaaca ccttttttat
    34081 gagtgtgaca cctagaacgg ctggatatta ttcagttgat tacctccata tgagccatgc
    34141 aggtctgatt ttaacgatgt ttttgatgta catcggcgga acatctgggt cgacggccgg
    34201 cggattgaaa acaactacgt taggtgtgtt gctgatccag atgcgttcga tgttgaaagg
    34261 acgtacgaga gcggaagcat ttggccgtac catccgacaa ggcgcagtgt tgcgggcact
    34321 tactttattt tttgttacgt tgacgttgtg tgtagtcgcc atcatgattt tatcggtgac
    34381 tgaaacgata cctaaaactt ctggcatcga atatattgct tttgaggtct tctctgcgtt
    34441 tggtacagta ggtcttacga tgggattgac gccagacttg actgcaatag ggaaattgat
    34501 cattatagcg cttatgtaca ttggacgagt tggtgtattg actgtggtct tctctctgat
    34561 gacaaaagca caaagaacac aatcaaaata caaatatcca gaagaaagtg tcatgattgg
    34621 ataatttcat cttctgacag aaacctagtg atttagtaaa ataagaaaat aaaataattt
    34681 ttcttgcttc ttggatactt taagtgcaaa atgttcgttt attttttgag gcactacccg
    34741 ttgttgaacc tcgggtagtg cctctttttt attgaaagga atcaataaga tttgattcct
    34801 ttatttatca ataggttata attcatattt ttttattttt tcttttacga tacttagtcc
    34861 agaagctaaa atttcaaggt tattagagga tagggaaatt cgaacgaatg catctggttg
    34921 cgcacgtgta gtaaagcgtc tggaatgata aagtcggata ccgttagcaa gaaagtcatt
    34981 ctcaattatc ttagggtcaa tctcaggatc aactggaaga attcgatagt aagggacacg
    35041 attcgttggt ttttctactt tgaaaagaga atcaaaaagc tgattggctc tttttgtaag
    35101 acttaattta gtttctaaga tcctatttgc ttcatttgaa tggaggattt gagtgatgac
    35161 ttccacatct aatccagaag ttttcacatt tatattaaaa attgcttgtt ctatcttgct
    35221 ttggacatgt actggaacta caagataagc aactcgcaat ccagaacaaa taaattttgt
    35281 cattccagct aagtagattg tttggttagg taataaattt tggaaaggag gaatgatcgt
    35341 atgttgatag taagttgtta aaaatgaatg gatatcatct tcaataaccc atagaccttc
    35401 tttttcaatc acttcggcta attgctctcg tcttttgtga gagatttgaa accctatagg
    35461 attattacaa gaaggcataa gaaagacacc atgaatcttc ttttttctac attcctgaat
    35521 caatatatca ggtcgcattc cttgctcgtc aaaatcaatt ggaacgatct ctaaatgata
    35581 taactgagcc aattcaatga aattagcgta tgtatatcgg tctgttgcta ttctatcacc
    35641 tggagagaaa agtgcagaaa gtgtgatagc caatccattt tgaacaccgg aaacaataga
    35701 tagagattct aaggacggaa tgactccttg agtttttaac caatttgctg cagtagtcaa
    35761 ttgaaaattt gtgcctttgg gatcttggta attaagcaaa ccaacaagat ttgggttatt
    35821 actagttgat tgaataaacg ggacaacgaa tttattacat tcttcaaaag aactaaccag
    35881 accaaaatca atgatatgtt cggttacttc attggtagag atggtgatgg actcaaagac
    35941 attgggagaa ataaatgtgc cacttccaat attcgtatac agcaaacctt tctcaattcc
    36001 atatttataa gccttgccaa cggtagtaaa atttaaatct aaataatcag ctagctctct
    36061 ttgggagggt aactgagtgt ttttctgtaa tttattcttt aaaatatctt gttctaattg
    36121 ttgaatcaac gatcgataat aaggacgctt caatttttgt ttgtctggtc gccaagttaa
    36181 cgggtaattg tcataagaat taataggcat tttctccact ccttaaaatt gtataccata
    36241 caattttacc attgattgta ttgattttag aagttaatct tttgtgagga gggaattgtc
    36301 tatgaaaatt attaattttg aggaagtagt agcttctttt agttttgaag aagcgattca
    36361 agtaatgaaa aaatgttttt ttgattatga aagtggtaaa atcagccaaa atcctcgatt
    36421 ggtggaaatt ttacctgacg gaaaaggcaa aaatatgttt gcgatgatgc ctgcttattt
    36481 gggggagaac agatattttg gcacaaaagt cattaccgct tttccggata atcatcagta
    36541 tcatttacct tctcatttag gagagatttt cttgtttgat gctcaaaacg gactacccaa
    36601 agcattgata aacgcaaatg cagtcacctg gattcgaaca gctgctgtat ctgcgctggc
    36661 aacagattac ttagcaaatc cgcatgcaga aacacttgct ttaattggag ctggtcaaca
    36721 agcattgtcg catttgactg cgatttctac cattcgtccc atcactacag tgtttgttta
    36781 cgatatttta gaagaaagac gaaatacttt tatcgctaaa gctaaaaaac agtatcctaa
    36841 aataacgttt ataaatgcaa tatcagtaga agatgcagta cgtccagcgg aaatcatttg
    36901 tacgttgacc tctagtaaag aggcatttct tcaaaaagag tgggtaaggg aagacgcaca
    36961 tatcaatgct gtgggcacat ttactcctga tacaagagag ataagtacat cgttgatgga
    37021 aacttctcaa atctatgtag atgattactc agctgcctta acagaaagcg gggacctgct
    37081 tatagccatg gcagaaggag atttagagga atcttgtatt gttggtacat taggcgaatt
    37141 agtttctgag aaaaaaacat tttataaagg agaatcgagg ccgacgattt tcgacgcagt
    37201 tggtctagct attgaagatc tttgttgtgc agaatatatt tataacaaat tagagaaagg
    37261 ggctttaaaa tgaacttaga ttattacgta gttgatgcat ttgcagatga ggtgttcaaa
    37321 ggaaatccag cagcggttta tgtgctagaa gaatggctgc cagaaggtac gatgcaaaaa
    37381 attgccattg aaaacaattt atctgaaaca gcatttacag tgaagaaaaa ccaagaattt
    37441 gagcttagat ggtttacgcc agatcgagaa atcgatcttt gtggtcacgc gacattagca
    37501 acagcatttg ttttatttaa ctattacaaa atacctgatg aaacgattaa attttctact
    37561 caaagcggta atctatttgt gacaagaatt aaagattatt attacatgga ttttcctagt
    37621 attatgccga aaaaagtgcc gatattgtct gaatatgaag aagcgattgg ggctaagatt
    37681 aaagaagcct acttagcacg tgatttattt ttcgtattag aagatgaaaa aacggtggct
    37741 aaattgcagc cagattttac agctatcaaa aattttgaat taggaatagg agtcatcgtg
    37801 acagcagaaa gtgtgcaaaa agactttgtt tctagaacct tctttccaaa attaacaatc
    37861 aatgaagatc cagtatgtgg atcagcacat tctaatctta ttccttattg ggcagaaaga
    37921 atgaataaaa caaaattgtc agcttatcaa atgtcatcaa ggggcgggga tctagaatgt
    37981 gaattaaaag aagatcgtgt gataatagga ggaaaagcag ttttgttttc taaaggtacc
    38041 tcgtttattt gatttctttc aaatgaatta aaaataaatt ggtggagagt ggcaacctta
    38101 tagctacaat ggttgttaaa aaaagacgca aactttttca atttaatgaa aagtttgcgt
    38161 ctcattttaa ttattggtgt ttgtttttta ttcaatcaag agtaaaatgc cccatactaa
    38221 ctatcctcgg atgacttcga ttttataacc atcagggtca atgacaaagt agtaagaagg
    38281 cgcagtgcca ggtaatcctt ttaagtcagt aatctcaaga ccagcagctt tatgttgctc
    38341 gtgtaatttt tctagatcat cagctgctat agcgatatga ccatagccgt ctcctagatc
    38401 atacgcacca tgatcatagt tgtaagtcaa ctctaattca tagtcatccc caggaagtgt
    38461 caaataaaca agtgtaaatt tgttttctgg aaaatcacgg cggcggcttt cttcaaaacc
    38521 aaatgccttt tgataaaatt cgattgatgc ttcaagatct ttcactcgaa cacatgtgtg
    38581 agccattttc atagattcat ctctcctttt ccttttactc aatcataaca aaaagaagta
    38641 aggaaatagt tgatttgtgc ttgttcatga gaaatttctc atgtaaaatg gatagaaaat
    38701 aaaactgtta aggtggaaac tattcatgga taaaccaatt tttggtgaaa aaaagcaatt
    38761 tgctgattat caaacccgtt atgcagcata tattgtcata gaaagagatc agcagattgc
    38821 agtaatcgag gctccaaatg gtgctttttt tcttcctggc ggggaaattg aaggagaaga
    38881 gacgaaagaa gaagcgattg tccgtgagct gatagaagaa atgggaattg tggcagaaat
    38941 ttcttcttat ctgggagaag ctgatgagta tttttactcg aattatcgtg caacttatta
    39001 ttataatcca ggatatttct ttgttgctga ttcttggaag cgtataggag aaccaactga
    39061 aaagaccaat aaaatttggt gggtgagccc tcaagaagcg cttgtgaaat tgaaacgtgg
    39121 tagccaccga tgggcagtcg agagatggat cgaaaaaaat aaaaactgaa agaaagcgag
    39181 tagatcagct ttctctcagt ttttttattt attacagtac atattttttg attgcttcag
    39241 ctacaccgtg ctcgtcgttt gatgaagtga tgacatttgc tgcttctttg acaagagaaa
    39301 cggcatttcc cattgctact cctagaccag catattcaat catggataag tcgttctcgt
    39361 tatctccgat agccatgatt tcatcttgat caataccaag gtgctgtgcg agattcgcaa
    39421 ctgccgcacc tttacttgct tctttattta gtacttcgaa gtaatagggc gcacttttga
    39481 ccgttgtgta tttatcacgg aaagtttgcg gtaaacgcgc aattgctgca tctaaaattt
    39541 ctggttcgtc gatcatcatc attttgacga tgttcatgtc tggtgtcatt tcttcaggtg
    39601 ttcgatattt tagcggcatc ttgactaaac ttgcttcgtg gatcgtataa gcgctgatat
    39661 ctcgattagg cgtgtagatc gctttgtcat cgatcgaatg gagatgactg ccgacacggc
    39721 gtgccattac ttcgatctct aggaaatctt catgtgtcag tccgtgacgg gcgatgattt
    39781 tacctgattt cgtttgttgt acgagtgccc cgttataagt aataacgtaa tcattatctt
    39841 gaaaaaggtt caactcgttt aactgttcct ggacacctgg taagggacgg ccagtgcata
    39901 aaacgatcga aacacctttt gcaacagcag cggcaatcgc ttcttttact tcttttgtta
    39961 cttctctttt ctcatttaat aaagtaccat cgatgtcgat agcgactagt ttgatagaca
    40021 taatttcctc caatatattt taatttattt caatcaatgc gccattacgg atatggctgg
    40081 caaattcttg ataagtttcg tcaaataaat cataatgatc acgcaaggac ggatcaacca
    40141 tttcttttgg aaagaaaaat cgctcatctc cttgttcttg tcccgctaat gcagcaacaa
    40201 gctgactaac ctgtgataat tctatcaaag ttccgtcatt tcgcaaaatc tcgatttgtg
    40261 tgcgatgtct gccttgttct gggcgataaa aatcataagg tagatcgtag ctagaattca
    40321 cagcagtgta ataaacagga ttatatccga ccttttctac taacaaagtg agttcttgga
    40381 ctaattttga atcccggttg ccagaaaaag tagcagattt cagtggttta cgattcaaaa
    40441 aacgtttagc taaatcattt aaaataggat cagcagattc agaccattga gtaaagtaag
    40501 tgcccaagac cccatcatca agtttgaggt attcttctaa agtaaagctt ccgtcaagaa
    40561 atggcagaag taattgagaa tggagttcaa aactgctggc atcttcttga tacaactcgt
    40621 gtgcgcgatg aagcagatgc tccaaaatta cttccatacc acgggaaaca ggatggaagt
    40681 acacttgcac atacatttga tatcggctaa cgatataatc ttccactgca tgcatgccac
    40741 tcatggaaaa agcgatcccg ccttcataag gacgaatcac acgtaatatt cgggtaagat
    40801 caaatgttcc atattctgtt ccagtgaaat aagcatcccg aagcaaatag tccattcgat
    40861 ctgcatcgat ctgactagaa atcatttgga caacttgtgg gttggggtaa gttttttgga
    40921 tcacactagc taccttttca ggaaaacctt cttctactcg gttaagaatc tgatacactt
    40981 ctgtttctgg agaagtgatg atctctacag tgatggcttc atgattcgta tggaagatat
    41041 gttcaaatgt atgagagtaa ggaccatgac cgacatcatg caacagtgcc gcacataaag
    41101 tcaccagccg ttcctgatca tcccagcctc cgttgcctat tttttctttt gaaaaatttc
    41161 gagaaaagat atcgcagatt cgtcttgaaa tctcataaac gcctaatgaa tgagtaaaac
    41221 ggctatgttc tgctccgtga aaagtgaaag aagaagtgcc taattgttta atgcgtcgta
    41281 gacgttggac ttctttcgaa ttgatcaaat ctaagattac ttgatgctgg acatggatat
    41341 agttatggac tggatcacga aaaacttttt ccataggcag catttgatat ttataagggg
    41401 ttgtcataat gtagctcctt tatgttatta cgttgttcca ttctctggat ttggttgttc
    41461 cattgctcca gctggatttc tttttttagc cagtcggtag aatcctgtaa atcacttgca
    41521 gaatacagct tttcaaaagc ttttgcaaat gcttctttga cttcttttac aaaaaggggt
    41581 tggtcaagca gttcttcaag tgttgccatt gtagcaggat ccactgcagg atagccattt
    41641 gtaccaaagt cttcttttaa agcagattga taaaatcgct tcatgacttg cccacgtttt
    41701 tcctgattac cgttgacact taagtacatc ataacagaaa tcccattttt gatccgacgc
    41761 tgagcgatac cggcaaattt tttgccatgg atgcttaaat cataagttcc aggacaataa
    41821 gaatgggtga tttcgaatgc ttgtatcggt gcctttggaa aagcgtattt agtcaatagg
    41881 agcatttgct cgtaagcgtc atctatggtt attttttttg tgtcactttg ggggaaaatc
    41941 aaagaaatat tcaaaattcc ttcatctgat acgatcccta atccacctga atttctgatc
    42001 actggagcgt aacctgcatc ttccagtgtt tggatcccgt cacttagaaa aggagttcga
    42061 acatccttca tacctaagat gactgtgcag tcatattgcc agaaatgtaa aaagatttgc
    42121 tggtgttctt tagaatattc cgttaatata tctgttaatg caaaagggga aaagtcgttt
    42181 ttttgataaa tgtgctgatc tagtcgaatc gcagggttca ttcaaccggc tcctttgtat
    42241 aaattcatat tttctacaat attatactct aaaatcaaag agttgttttg gaaaaaaggt
    42301 tttctgtaaa aatggacaag ttggttgaca aaacaaaaga aactaggaac aatgtagcta
    42361 tgagaagtaa aggagaatga ataatggaat tatcacaagg aacaccgatt tcaatcaaat
    42421 tgcgtacaaa agtaaaacag caaggggaag tgcaagattt ttattttgat ttgaaagggc
    42481 aaatggtgac aattggcgat acgctgtaca tacgttataa agagattcag gaggagacgg
    42541 gcgatgagat tcctgtaacg atcaaattag ttccagatgg tcatgtacag ctgatccgtg
    42601 caggagaaat gcggatgcgt ttgaaatttg gctataaaga acggttagaa acatcctatc
    42661 gaacaccata cggtatgatc cagattgcta cttttacgaa agaactgcat gttagtttga
    42721 aagaccgtcc cacagcaggg aaggttcgaa tcgattatga tctgttcatg ggaccggaaa
    42781 aaatcggcga atattatttg accttggatt ttacagcgta aatataaaag aaaagtttga
    42841 ttttttgtgt ctgattttgt atgataagga gtagactgtg aaaggacgtg tcctgattgg
    42901 aaattagtgt atttgaaggt gcaaacaaaa gcgaattatc aatgatcgaa gtagcacacg
    42961 cgatcttaga acaacgtggc gatgtcatgg atttttctga tttagctaac cagatccaaa
    43021 actatcttgg gaaatcagac agtgaaattc gtgattcact cgcacaattt tatactgact
    43081 tgaatattga cggcagcttt atctcattag gggataatcg ttggggcttg cgttcatggt
    43141 atgctatcga ttcgatcgat gaagaagtaa accatggaat ggacgaagag gatgaagata
    43201 ctccacgtcg ccgtaaacgc aagaaagtca acgcctttat caatgatgat gaagacgcga
    43261 tcgattacaa tgacgatgac ccagaagata cagatctgac agaagaagat gacgatgatc
    43321 tgtttgatga cgatgatgat gaagatgaag aaatcgctgc ttataattct gacttgcaag
    43381 aaatcggagc agatgacccg acagatgatg aagaagactt gccaggaaat atcgaagaag
    43441 atttaagtat catagacgaa gacgatgatg atgaagatta tgaagaggaa gaattttctg
    43501 actctgaaaa agaataaaca ttattttctt acgagaggtt gtgacagaga cgatcagcct
    43561 atcagaataa ggaggtgtga cacgatttt
//
LOCUS       DACDLM010000019        41494 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.019, whole genome shotgun sequence.
ACCESSION   DACDLM010000019 DACDLM010000000
VERSION     DACDLM010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.019"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(1273..1938)
                     /locus_tag="IV356_001042"
     CDS             complement(1273..1938)
                     /locus_tag="IV356_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP9014747.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            2064..4100
                     /locus_tag="IV356_001043"
     CDS             2064..4100
                     /locus_tag="IV356_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HAP9014748.1"
                     /translation="MIIKKKFTVLLTIIVTGIMSGFALVSINKQVLYRTNEFFHQTDT
                     YTPIRLPQHFIGQEEYEQLIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLE
                     MTLYYQGDVKSSHEKVPYSNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLF
                     TDRFNQAFHTDYATNIFEDFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLL
                     MNKEISLLLNNDFSLHQVLWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYV
                     FLFSGIYGISLISLLLVEKIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFS
                     SSQLAVSHEPPKEIAGEDYHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSI
                     LVNVSDYLNEENEQFGRGIKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRH
                     TDLKNDLAQITEYYQEISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSM
                     YLERNILSGEIYPPLKIKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLS
                     RSFHYLIQIFLLTFFSFFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNL
                     IKWGTTSVIFLFLIEREPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            4104..4742
                     /locus_tag="IV356_001044"
     CDS             4104..4742
                     /locus_tag="IV356_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9014749.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            4770..5198
                     /locus_tag="IV356_001045"
     CDS             4770..5198
                     /locus_tag="IV356_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014750.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            5655..6566
                     /locus_tag="IV356_001046"
     CDS             5655..6566
                     /locus_tag="IV356_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP9014751.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            6783..7220
                     /locus_tag="IV356_001047"
     CDS             6783..7220
                     /locus_tag="IV356_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014752.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            7315..8199
                     /locus_tag="IV356_001048"
     CDS             7315..8199
                     /locus_tag="IV356_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAP9014753.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            8423..11590
                     /locus_tag="IV356_001049"
     CDS             8423..11590
                     /locus_tag="IV356_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014754.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            11610..12155
                     /locus_tag="IV356_001050"
     CDS             11610..12155
                     /locus_tag="IV356_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HAP9014755.1"
                     /translation="MNRIWNKSHRNNCSLLMILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKIQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILI"
     gene            12183..12638
                     /locus_tag="IV356_001051"
     CDS             12183..12638
                     /locus_tag="IV356_001051"
                     /inference="COORDINATES: protein motif:HMM:NF023225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
                     /protein_id="HAP9014756.1"
                     /translation="MKLKKAYADQSDGRNVIKANLQNPNASYMFGLTTSVEIYKKETK
                     EPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKGAWKEKRWNLHTDFEITD
                     DAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFILKERRKKK"
     gene            12635..13393
                     /locus_tag="IV356_001052"
     CDS             12635..13393
                     /locus_tag="IV356_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAP9014757.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            13894..15093
                     /locus_tag="IV356_001053"
     CDS             13894..15093
                     /locus_tag="IV356_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP9014758.1"
                     /translation="MLFTSGPDRAFERLMQEKPGFDHYDGGGADAPEDCGTCRFYRPD
                     WKYQFCQFAECPYQPGKLTDYAAVKFTVKGANNAMAVFRVEKNKGYTVMSNHHLRNKN
                     LTLKAKGLLSQMLSLPEDWDYTLKGLSYINRESIDAIRTAVWELEKAGYIRREQGRDA
                     KGKMADMVYTIYEQPVLENPVLENPTSDNPVLENPTSDNPASENPTQLNKEVQRTDLS
                     KKEKIITDGQSTHSIPIPSPTPAPMEGEAAATPPERKRTGKDEAVRIYREIILENIEY
                     AYLIQDRSIDREQLDEIVDLMLETVCTARKTIRVAGDDYPAELVKSKYMKLTGEHIRF
                     VLDCLRENTTKVRNIKQYLRAMLFNAPSTISNYYTALVAHDMAQPDWGKPKSGLPDYS
                     CGEGESL"
     gene            15115..15327
                     /locus_tag="IV356_001054"
     CDS             15115..15327
                     /locus_tag="IV356_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HAP9014759.1"
                     /translation="MKQGALIFDERTDRYDIRFDLADYYGGLHCGECFDVMIGGKWRP
                     TRIEMAENWYLVGIRADDLSGLRVRI"
     gene            15402..15878
                     /locus_tag="IV356_001055"
     CDS             15402..15878
                     /locus_tag="IV356_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HAP9014760.1"
                     /translation="MQEEVTQKTIALSMKTGKLTAQVLQAALKKYLQHRAKGKNTLHH
                     GQQSLKQLKKHGADLSNIEITEANIGAFKPCAKKYGVDFTLRKDKTTQPPHYVVIFKA
                     KDADNLDLAFREFTAKTLSKEQRPSIRKVLSAVKQKAAAQTKQRAKEKIKERGLEL"
     gene            15875..17683
                     /locus_tag="IV356_001056"
     CDS             15875..17683
                     /locus_tag="IV356_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003819036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HAP9014761.1"
                     /translation="MKPDVKKLLILNLPYLIFVYLFAKCGEAYRLAAGADLSGKLLHF
                     ADGFAAAFANPLPSLHLFDLCIGIAGAVIVRLVVYCKSKNVKKYRKGMEYGSARWGTA
                     KDIAPYIDPKFENNILLTQTERLTMTGRPKDPKTARNKNVLVIGGSGSGKTRFFVKPN
                     LMQCFPTTDYPTSFVVTDPKGTLVLETGRMFQQAGYRIKILNTINFSKSMKYNPFVYI
                     HSEKDVLKLVNTLISNTKGEGEKSAEDFWVKSERLFYSALIGYIWYEAPAEEMNFSTL
                     LEMINASEAREDDPEFQSPVDLMFERLEQKDPDHFAVRQYKKFLLSAGKTRSSILISC
                     GARLAPFDIREVRELMEDDEMELDTIGDEKTVLYLIMSDTDTTFNFILAMLQSQLINL
                     LCDRADDVYGGRLPVHVRLILDEFANIGQIPNFDKLIATIRSREISASIILQSQSQLK
                     AIYKDAAEIISDNCDSVLFLSGRGKNAKEISDALGKETIDSFNTSENRGSQTSHGLNY
                     QKLGKELMSQDEIAVMDGGKCILQLRGVRPFLSEKFDITKHPRYKYLADADKKNTFDV
                     DRFLTITRRKRQQVVTQDEVFDLYEIDLSDEDAAAE"
     gene            17760..17975
                     /locus_tag="IV356_001057"
     CDS             17760..17975
                     /locus_tag="IV356_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugative transfer protein"
                     /protein_id="HAP9014762.1"
                     /translation="MAFFNSAVTTLQTIVIGLGGALCVWGGINLLEGYGQDNPGAKSQ
                     GVKQLVAGGGVALIGVTLVPLLSGLLG"
     gene            18067..18930
                     /locus_tag="IV356_001058"
     CDS             18067..18930
                     /locus_tag="IV356_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014763.1"
                     /translation="MISEIIEEWIKGILMDGITGNLSGLFDTVNAKVGEIAADVGRTP
                     QAWNSGIFNMLHSLSETVIVPIAGAILALVMCYELIQMITEKNNMHDFDSSMFFRWIF
                     KSAFAILIVTNTWNIVMGVFDATQSVVNQSAGVIIGQTSIDFNTLIPDLESQLEAMSV
                     GALLGLWFQTLVVGLTMNILSICIFLVTYGRMVEIYVVTSLGPIPLATMGNAEWRGMG
                     QGYLKSLLALGFQAFLIMVVVGIYAVLIQNIGSASDISGAIWGCMGYTVLLCFCLFKT
                     GSISKAVFGAH"
     gene            18961..19503
                     /locus_tag="IV356_001059"
     CDS             18961..19503
                     /locus_tag="IV356_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methyltransferase"
                     /protein_id="HAP9014764.1"
                     /translation="MFISTYNIIYADPPWRYDCKNVQGAAENHYSTMSIDELCALPVE
                     RLASKDCLLFLWATFPMLPEALRLIKAWGFSFKTVAFVWLKQNRKSLTWFYGLGRWTR
                     GNAEICLLATHGKPKRRSASVHQFIISPIEQHSKKPDVTREKIVELAGDLPRVELFAR
                     QKTPGWDVWGNEVECDLILT"
     gene            19517..19939
                     /locus_tag="IV356_001060"
     CDS             19517..19939
                     /locus_tag="IV356_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HAP9014765.1"
                     /translation="MAYVTVPKDLTHVKSKVVFGLTKRQLICFSGALVIGVPLYFLTR
                     DYLTNSAAALLMVFAMLPGFLLAMYERHGQPLEVVIMQIIQCCFIQPKERPYQTDNTY
                     TALVRQYQMEQEVKAIVQKGNPKRNRKNKADPRPAKRN"
     gene            19869..22268
                     /locus_tag="IV356_001061"
     CDS             19869..22268
                     /locus_tag="IV356_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HAP9014766.1"
                     /translation="MSKKEIPRETEKTKLTRAQRKEIDAVIRKYKGDGRPHTAQQSIP
                     YEVMYPDGVCRVSPGVFSKCIEFADISYQLAQPDTQTAIFEKLCDLYNYVDASIHIQF
                     SFLNRKVDPVQYAKSFEIAPQGDDFDDIRAEYTGILQKQLANGNNGMVKTKYLTFTIE
                     AESVKAARARLKRIGFDLLGYFKSMGAVAHVMDGWERLNLLHGVYHPDGEIFNFDWKW
                     LAPSGLSTKDFIAPSSLCFGNAKTFGMGGKYGAVSFLQILSPELSDDMLADFLNTESG
                     VLVNLHVQAIEQTKAIKTIKRKITDLDAMKIAEQKKAVRSGYDMDILPSDLATYGEDA
                     KKLLTKLQTRNERLFQLTFLVLNVADTKQKLNNDVFQAAGVAQKHNCPLVRLDYQQEQ
                     GLASSLPLGVNQIKIQRSLTTSSVAVFVPFVTQELFQGGAAMYYGINAKSRNMIMLDR
                     KQARCPNALKLGTPGSGKSMSCKSEIVSVFLTTPDDIFISDPEAEYYPLVKRLHGQVI
                     RLSPTSKDFVNPLDINLNYSEDDNPLALKSDFVLSFCELVMGGKNGLEAIEKTVIDRA
                     VRVIYRPYLADPRPENMPILSDLHKALLDQHVPEADRVAQALDLYVSGSLNVFNHRTN
                     VDIGNRLVSFDIKELGKQLKKLGMLIVQDQIWGRVTANRSQGKATWYFADEFHLLLKE
                     EQTAAYSAEIWKRFRKWGGIPTGATQNVKDLLSSPEIENILENSDFITLLNQASGDRK
                     ILAERLNLSTEQQKYIDNSEPGEGLLIFENVVLPFTNPIPHNTQLYKIMTTRLNEVAG
                     V"
     gene            22300..24291
                     /locus_tag="IV356_001062"
     CDS             22300..24291
                     /locus_tag="IV356_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006060479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HAP9014767.1"
                     /translation="MKELKAKAKVTQAMTRDGLTLENQATGEVENISSREAEQDLSAP
                     GPGGTADKLLERADAIHDGHKAKKAAKQAGAVAAEGDAALHRPSARLQLSEEERADPD
                     LQPYIRKSDKRADKLDKARAAIPKKRVPVKETVFDEASGKAKTVLHFDKQDKGPPSLK
                     PNPAGRPVSEVFLFGHGKIHEVEHENVGVEGGHKGEELAERQAGKAIRSTIRHHRLKP
                     YWDAEKAERRLLSANAEYFYQKSLRDNPEIAQAASNPISRFWQKQQIKRQYAKAARTA
                     GQTAGAAAQGAAKTAGASTKAAKAAAKESERAASFVARHWKGALAVLVLGLLMLLIIG
                     GLQSCTAMFGSAGSGITASSYFSEDSDMLAAEDAYAELEAELQDYLDNYEATHDYDEY
                     HFDLDEISHDPYVLISILSALHDGIFTIGEVQGDLSMLFDKQYILTENVVVETRYRTE
                     TDTWTDAEGNTHTDTYQVPYDYYICYVTLENFDLSHVPVYIMDEETLSFYSLYMSTLG
                     NRPDLFSGSQYPNASTLTPPTYYDVPPEALEDATFAAMLKEAEKYIGYPYVWGGSSPS
                     TSFDCSGFISWVINHSGWNVGRLGAQGLYNICTPVSSSQAKPGDLVFFKGTYDTPGVS
                     HVGLYVGNNVMLHCGNPISYTNLTSNYWQSHFYSYGRLP"
     gene            24314..24565
                     /locus_tag="IV356_001063"
     CDS             24314..24565
                     /locus_tag="IV356_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HAP9014768.1"
                     /translation="MATKLDRIEKDIQKTKSKIAEFQKQLRELETQKTEQENLQIIQL
                     VRGMNMKPEEFAAFLRSGAMQAAPAATPYHEQEDNAHEE"
     gene            24555..25784
                     /locus_tag="IV356_001064"
     CDS             24555..25784
                     /locus_tag="IV356_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HAP9014769.1"
                     /translation="MKNKTRRISRILPALLAVMLCVTAFPVTALAGGNDPAPAPLPEA
                     TTEPATGGLEPETDETGTATDGTETEAEKDTGPLTGKDITDLFSALFGSKVSIAATDD
                     GIQITTGTDKKEPEQTGTVTTNGGRLNVRTGAGLDKTAFTQLPNGTTVEVVGTDGDWI
                     KILLPERIGYVHSDYMTVSEKEVAATGEGGFSLSIDPEEIASLLELFNGGGASAALSP
                     DGNLSLIDDIGSAAKNGKQFITVETKNGNVFYLIIDRDDEGKETVHFLNQVDEADLLT
                     LMEDGETVTPAAVCSCTTKCKAGAVNTNCPVCKTNLTECSGPEPQEPQPEEPEAPEEE
                     PKGGAGGLIVFLLVALAGGGAALYYFKFKKPKAETTGSDDLGEYDFGEDEDLEDEEPE
                     TEFDPEADFVSEQEDEE"
     gene            25781..27862
                     /gene="topB"
                     /locus_tag="IV356_001065"
     CDS             25781..27862
                     /gene="topB"
                     /locus_tag="IV356_001065"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP9014770.1"
                     /translation="MTYKLVIAEKPSVARSIAGVIGATEKHDGYLEGNGYLVSWCIGH
                     LVSFADAGRYDERFKKWRYEDLPILPETWQYIVPDDKKQQFDVLCSLMQRPDVTGLVC
                     ATDAGREGELIFRFVYQMAGCQKPFERLWISSMEDSAIKDGFAHLKPGGDYDPLYQSA
                     LCRAKADWLIGINATRLFSVLYHKNLTVGRVQTPTLKMLVDRDAKITDFKKEKYHIVH
                     ITAGGADAVSSRFSDAAEANTVKAACAKAQAVCVSVTREKKTEQPPKLYDLTTLQREA
                     NRLFGYTAKQTLDYAQALYLKKLLTYPRTDSQYLTDDMLPAVESLVSGLWELVPFAKG
                     LNLSPQFDRILNSKKVSDHHAIIPTAEFVKQGFGTLAESEKKLLSLICCKLLCAVAGP
                     HIYEAVTATFTCAGQEFTAKGKTVLSPGWKEIERRFRSSLKTDADEDAEAVRELPELC
                     EGQTFADVAASVTEHFTTPPKPYTEDTLLSAMERAGAEDMPEDAERKGLGTPATRAAI
                     LEKLVQMGFVQRKGKQLIPTKDGINLAVVLPEALTSPQLTAEWENRLTEIAKGQADPD
                     EFMDGIETQARELVQTYSCISEEKQKLFQAERVPIGTCPRCGEAVYEGKKNYYCGNRA
                     CQFVMWKNDRFFEERKKAFTPKIAAALLKTGKVKVKGLYSVKTGKTYDGTVLLADTGG
                     KYVNYRIEHRS"
     gene            28011..31931
                     /locus_tag="IV356_001066"
     CDS             28011..31931
                     /locus_tag="IV356_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HAP9014771.1"
                     /translation="MNEVFSIQVHNRQFLEQGKQGVWLDLPTTTETLQAALRDVGITA
                     DNPQDFFINGYSCPEDRHLAIPYDMVLAADVDELNFLAARLGQLDAAEIAELNAALQN
                     PRGGFENIGQIIDYTENVDYYVHLPDVRGDGQLGDYYLNRSGMVDMPEEWKAGIDTAQ
                     FGRHIAQQEQGVFTQYGYLVRSGDEWQRVHEGQPVPEEYRVMHYPQPEADREEPQAQQ
                     PEASESPDKAPPPVIPIMLDGMNSKERMKVITDRLETGVQELFESSRYMAYLSAMSKM
                     HDYSLNNTLLIAMQGGSIVAGYNRWQDEFDRHVKRGEKGIKILAPAPFKVKQQMEKID
                     PATQQPVIGADGKPVTEEQEVTVPAFKVVTVFDISQTEGKDFPMPYISELTGDVQQYQ
                     DFFAALERTSPYPISIEPISDGAKGRCFYAKQRIAINEGMSELQTLKTAIHEIAHAKL
                     HAIDREAPAEEQAARPDRSTREVQAESVAYTVCQYYGLDTSDYSFGYVADWSSGRELS
                     ELKASLETIRATASELITEIDGHFAQLQQEREARQEQEAVTVDVTPEAAAPAQAEEEQ
                     APALDPAAEPLVTVLWSESPQLKDGQQMPLHEADALFARLDAAYPAEAGYDKTAFRID
                     CIFQGEPDSYEGRQDFGDRDGSLIEHIQSYHQFYAQDENWKKHVIATTGIEGWEQDKA
                     HRDMLLGEFVPYMKLHCSLAQMEQTAQGRLQSGETLTPEETAYLGALLSYVQECRPML
                     NQGQYQLPEPPKLADFDQSLQDYKAQVQAEIAQEAAAAGMTVEEYAAAGYEAPQQDTF
                     SIYQLRGGEETRDYRFEPYERLQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNID
                     HPADFRGHSLSVSDVVVLHQNGQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNEN
                     MIDGIINNTPPEPQPEEPEQLSFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAAR
                     RAKEAMSFSDYRPGSATAEYRHYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLA
                     ENMNKGYEITARVPSVLIAGPSNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGM
                     GGISADDPQAVSKLEKKLEKLEASQELMKAVNAYYRKHGTLDGCPHLTERGIENLKAD
                     MASGWHYEKKPFQSWQLSNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVA
                     NRLQIFFEGKPDAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEK
                     PSALQLAARREKEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            31932..32876
                     /locus_tag="IV356_001067"
     CDS             31932..32876
                     /locus_tag="IV356_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014772.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            32880..33083
                     /locus_tag="IV356_001068"
     CDS             32880..33083
                     /locus_tag="IV356_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014773.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMPVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(33383..33619)
                     /locus_tag="IV356_001069"
     CDS             complement(33383..33619)
                     /locus_tag="IV356_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP9014774.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(33802..34173)
                     /locus_tag="IV356_001070"
     CDS             complement(33802..34173)
                     /locus_tag="IV356_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014775.1"
                     /translation="MSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECICVQSI
                     SYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAACSKRM
                     RRRKEAERQRKRYWKPTHLEL"
     gene            complement(34170..35498)
                     /locus_tag="IV356_001071"
     CDS             complement(34170..35498)
                     /locus_tag="IV356_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAP9014776.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            complement(35459..35788)
                     /locus_tag="IV356_001072"
     CDS             complement(35459..35788)
                     /locus_tag="IV356_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HAP9014777.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            complement(36046..36417)
                     /locus_tag="IV356_001073"
     CDS             complement(36046..36417)
                     /locus_tag="IV356_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP9014778.1"
                     /translation="MANIEDCPGFETFGADVKAARQAKRVSRKAMAEKINIDWRYLAN
                     IENDGAIPSLPVVIQLIKACGLPVERYFNPEIMREESELRQRVSHKLKLCPEEYLPII
                     EGAIDSAILIEKPKKNETEDV"
     gene            36562..36747
                     /locus_tag="IV356_001074"
     CDS             36562..36747
                     /locus_tag="IV356_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAP9014779.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            37690..38349
                     /gene="vanR"
                     /locus_tag="IV356_001075"
     CDS             37690..38349
                     /gene="vanR"
                     /locus_tag="IV356_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HAP9014780.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDLEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFESDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            38352..39695
                     /gene="vanS"
                     /locus_tag="IV356_001076"
     CDS             38352..39695
                     /gene="vanS"
                     /locus_tag="IV356_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HAP9014781.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPDFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQARSRKSGRNGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLTSTL"
     gene            39866..40672
                     /gene="vanY"
                     /locus_tag="IV356_001077"
     CDS             39866..40672
                     /gene="vanY"
                     /locus_tag="IV356_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-B/VanY-G family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HAP9014782.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGRR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            40685..41494
                     /gene="vanW"
                     /locus_tag="IV356_001078"
                     /pseudo
     CDS             40685..41494
                     /gene="vanW"
                     /locus_tag="IV356_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance accessory protein
                     VanW-B"
BASE COUNT        11616 a         9542 c        10338 g         9998 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgaggacta cctgtattag tcctcttttt
       61 tgaccagatt ttgaccagtc tattttacat tctaatatat tcatatgagc taattttatg
      121 attaaatggt aagtgtttcc ttgtttgttt tagtttaaac tagtgtgtaa tttaaaaatc
      181 tatatggaag ggtctgtggg gtaatactta aataaaggct aggaacctga taacatcaag
      241 gttcctagcc tttttataat aaaatgaagc gaaaataatt tcttttaaag agccgagatt
      301 atcagctata taagagtgaa tttgatgcaa aaaacagagc cgaaacagtc ttggtgttcg
      361 tagctctgct tatatgtttc gaatttaaga caaagagttg gcaaaagatg ttgataagga
      421 agataagata actgtgttat ataaactagg taactaactg taacaagcta attttaagag
      481 attcttatta gaagacgttt aggaatataa ctaagaaaat gattatacag gtaattgtca
      541 tttcaataat gttttctaat tttcgcgtct ttgttttaag aaaaaggcca gaatcagttg
      601 gaaaaaagtt cgtacgatag tgaagagggg caaaatttcc tactaatatt cccactaaca
      661 agagataaaa cggccaggtt ggtgtgattc ctctataaaa aaatgcccat gctaccgaaa
      721 tcccatagat taacaactga acaattttta caatgaaaaa attgttctgc cattactcaa
      781 agtctcttcc tccttgtatc gtttatttgt ttcattttat cattatgata ggcgcttgaa
      841 caatccattt tgtattttat tgagtactct tggataaact accagcgatt atcatattta
      901 tttatgttac tgtaagccat catataaaag taaatgagca gatcatagaa atataaaaaa
      961 gaactaaaat tgatctaaat tatgtgcagc ttgactacgt accaatctat attacttact
     1021 agattggtcg ttaatctatt cggatcgaat gagcaaaata tttttgtgaa tgtccatcct
     1081 tgattatgat tccaaaaaga atcattggga ggctgtggcg taaatattat actataagcc
     1141 agaaatacct atcattctga acttttttat ttaggaactt tcatctcaag gctttttcaa
     1201 ttaatttgta cccctgtttt ttggataaga tcatgtgcat tgattttttc tatctctacg
     1261 ttcatctcct acttaatgcc tatctggctc ctgagggctt ctttttaagg cgtcgtcata
     1321 gtcttggctg aggatttctt ggtaatctga gggaatggct tcccaagtga gcaggcgaac
     1381 gttcatgacg tgttttcctt tgtgtttgat tacagcatgg tttttctctt tttctacctc
     1441 tccagcgtga aaagacagcc atgtaccatg gccaaagata tcattacata cccaacgttc
     1501 gatggaattg tccacgtatc ctacagggag tgtggtatag ccgatttgtg gtttcaaaaa
     1561 aggattgaat cgatcgatcg tttcattttt gtattgataa ttgataagaa aaagatagac
     1621 caaacaaaag acgagcagaa agaaagatag tgtctttttg agtgagaagg gttgttttga
     1681 tgaataagat ttcttgttaa caagaggttc atctggcaat gttggttcta ttgattcggt
     1741 agctgattca atagaaggaa aatcaatcgg cagacctaaa gtatgatgta aaagtgacag
     1801 catttcaagg tctggcattg tacgagaatt ttcccaacta gaaatcgttt tatcggaaac
     1861 accaattttt tcgcctaatt ctttttgcgt aagcttacaa tttctgcggt aagttcgtat
     1921 tttttctccg gtgttcatct tcttctcctt tcgattctac agtatataga tttattctac
     1981 atgacctata cacttgatag atacgttttt ttgatgaaaa acggtatgat tttatcaaag
     2041 aatcatttaa gtaagggaga gtggtgataa tcaaaaaaaa gttcacagtt ttactcacaa
     2101 tcatagtgac cggtatcatg agtggttttg ccttggttag tataaataaa caggtactct
     2161 atcggacaaa tgaatttttc catcaaacag atacttatac tccgattcga ttgccacaac
     2221 attttattgg gcaagaagaa tatgagcagc taatcatggt atttgaaaat gtctcatcag
     2281 aaactgagct ttcttatatg aaaaaaacag taaatgaatc caatgaagta gatacatctt
     2341 ggaacttcaa gatacagcca aagcttgaaa tgacattgta ttatcaaggg gatgtcaaat
     2401 cttctcacga gaaggtaccc tattctaata cctcctttcg cgtaacgtcc attgaagaat
     2461 cgatcaaaat aaaagatttt gaaggtgaat ttttcttgat gacgagagaa aaagaagcct
     2521 atgaacggtt catttcacta ttcactgatc gattcaatca agcatttcac actgattatg
     2581 ccactaatat ttttgaagac tttgaaaata gctattcgta ttcggttatt tcaaatacag
     2641 acgtatataa ttatcgagtg tatttaacta ttggattgat tcttttattc cttttgttat
     2701 catccttttt cttattgatg aataaagaaa tcagtttatt gttgaataat gacttttcat
     2761 tacatcaagt attgtggtgt ttattgggga aaaagaaaat cattattaca ttcataattg
     2821 caggaatcat tggtggtttt atttttatgt attataagga gcaatttctt tatttgttcc
     2881 agatgtacgt tttcttgttc agcggaatat atggtatctc tttgatttct cttttattag
     2941 ttgaaaaaat cgcttcgtta agagaagcgt tcaactatat ccaatacatt ctttttacat
     3001 ttggattgtt gttttctctt cttttgaccg ttgccaatgt cgaattagca actatcgttt
     3061 tttcttcttc acagttagct gtttcccatg aaccaccaaa agaaatcgct ggtgaggact
     3121 atcatgtatt ttatccagta accatcggga aaaaccacgt ggattttatt tattccaatc
     3181 gttttgcatc agcagcagat caggaattat atgaaacttt gaataaaaac ggaagtatat
     3241 tagtcaatgt atcagattac ttgaatgaag aaaatgaaca gtttggcaga gggataaaaa
     3301 taaatctgaa ttatcttaag aaatttcctt tgattgatgt ctctggaagg ttgatccaaa
     3361 taaccgaaaa agaaacgcac cctgttatat tgatccctga acgatataga catacagatt
     3421 taaaaaatga cctggcgcaa ataacagaat attatcaaga aatcagtgaa aaagaaccga
     3481 aatttctatt tataaaaaac aatcaaccca tttatacatt tattccttct atcccctgga
     3541 tcgaacatta tccggttgtt gaaatactga cattgaaaaa cagtatgtat ttggaaagaa
     3601 atattctcag cggagaaatc tatccaccgt taaagatcaa gataggctct ttgtcgaaag
     3661 aaaggttatt tgagctgatt gaagaaagtc agttacgtga taacttgcag ttatcatttc
     3721 cgtatactca gactgaagag atagctgtca aagtgttaag cagatcattt cattacttga
     3781 tacagatatt tttactcact ttcttttctt tcttcttgtt gagctatgtc atgttatgca
     3841 tatattttgt ctacaattgt cggaaaatcg ctatctttcg ttcaagtggt tattcgctct
     3901 ttgaaacgta taaagatttc ttcatgatga acctcatcaa atggggaacg acaagtgtaa
     3961 tcttcctttt tcttatagaa agagagccta aatatctttt taatattttt ttctttagct
     4021 tcattgattt tattctttca gttgttttta ttttgtctac agaaaagaaa agtcagttat
     4081 tgctgatgaa tggaggttaa caattggagc cgttgatagt gataaaaggt gcgaaaaaaa
     4141 tcattcgaaa caaaacgatt cttcatttgg atcgtttcac tgcggatgct ggggatcttg
     4201 tgactgttgt tggagaaagt ggagcaggta aaagtacgtt attgaatata ttaggattga
     4261 atgatcagtt cagttcagga caattctatt tgttcgatca agagacgaaa caattaactg
     4321 ggagagagaa gcgcttgata aaaagaaata ccatatcttt tctttttcaa gattttgggt
     4381 tgattgaata tgaaacaatc gattttaatt tagatattgg attgaagttt tcgaatttaa
     4441 atgtttcaga taagcgaaca gcaaagtatg aggcattgaa aaaagtaaat ataaacaaga
     4501 agctaagtac gcctatctac acattatctg gtggtgagaa gcaaagaatc gcctgtgcga
     4561 gagtcttatt gaagaatagc aaaatcattt tagccgatga accgactggg tcattggata
     4621 aaagaaataa ggataaagta gttgaaatct tatcgcaaca agcttcccaa ggtacgttag
     4681 ttatcgtagt cacgcatgat ccatatctga ccaaaatagg aaacaagaag atcatgcttt
     4741 aaaaatcaaa aaggaaagga tgtcgtttta tgaaaaaagc agttattatt tgtgcactag
     4801 ggataggttt tgttggagga aacgctatgt catctgaagt ggaagcaaat tcagttcacg
     4861 gtgaaatcta ttacaaatct ttaaagccag gagagattca ttttgatgct aaaggtaata
     4921 ttattaagtc aaatttacca gtagaccggg aaatttctag aacagcaatt aatcatagct
     4981 ctggaagatg ggtttattat agtgatacaa cttgtacgag aaaaacaggt cattctaacc
     5041 actatagtcg tgtctataat cgtcacggtg caaaagcgaa agttggaaac tctattcgat
     5101 cagcaaatgc aacaaaagga gtatgggcct atgcaagtgc gacaggaaat agaactgaca
     5161 cattctcatg ttggtacaat ccaaccggtt ggtattaagt atccaaaagt ttatataaaa
     5221 tagaaaaaac atataatgaa acagcgttaa aagttatttt tggtagtttt aatatattca
     5281 tttttagttg tataaaaata tatcataata aaaacaacaa aaaaatgtct ggaaaatcga
     5341 acataaaagt gtctgatttg aatatcccag cagcggaaga agaaaaacaa aatcgataac
     5401 atttgttcta agaattagtt acgttaaata cggaacgcaa gatagacttg aaaaacggta
     5461 acaaaagaag tagtatatta aggtgtgatg tgctacttga catttattct gctgagcgaa
     5521 ctttctggat tgtgtagcct tatatctatt caggacgtat cgagcagatt agtaaaggtg
     5581 ttcttgatga ttttcatctt gaacaccttt gtttttagca attcgcaaaa aacgaaaagt
     5641 aggagaattg ataaatgaaa aaaagatttt tagcacttgc catcgtacta ggcactggct
     5701 tattgtcagg ctgtacgaat gccggtgaaa aaacagccgt tagttataaa ggcggtacaa
     5761 tcagcgaaca agaagtaatg gatagcttga aaaaaatgca aggagcagat tccgctgtgc
     5821 aacagttgat cgtttatcaa gtatttgaag ataaatatgg agatgacgta tcaaccaaag
     5881 aaatcgattc tcaatatgat caaacaaaga aacaattggg tgattcattt gattcacaat
     5941 tgaaatctgc aggttacaca gaacaaacat tcaaagacag tatcaaacaa agtctagcct
     6001 ttcaagaagg tctaaagaaa catatcaaat tgaccgatga agatttaaaa acggcttggg
     6061 aatctttcca tccagaagtg gaagctcaaa ttatccaagt agcaagtgaa gatgatgcaa
     6121 aagatgtgaa gaaagctgct gataagggag acgatttctc taaattagcc aaagacaagt
     6181 caactgatac tacgacaaaa gaagatggcg gaaaagtgaa atttgattcc actactacaa
     6241 cggttccggc agaagtcaaa gaagcagcct ttaagttgaa agatggtcaa gtttctgatg
     6301 tgatcacttc taccaatgct tcaacttata ctacggaata ttatgtggtt aaaatggtga
     6361 aaaaccaaaa caaaggcaac gacatggata aatacaaaaa agaattgaaa gaaattgcaa
     6421 cagacacaaa attaagtgac agtaccttcc agaataaagt aattggcgaa gtattgaaag
     6481 acgctaatgt aaaaatcaaa gacaaagact ttgaaaatgt tttgagtaca ttcacttcag
     6541 attctagtac agcaagtagt aaataagcgg tataaataaa aaatatgaac tatttaaatc
     6601 aataaaactg ttcatctaaa tctttttatt agaactaaat caacagtagt ttaattacta
     6661 cttgatttag ttctttttat tttaaaaatt ttttttactt agaatccagc gaccctagat
     6721 atttttctgt ataatcttaa ataaagaaaa caatatcaaa aaatgcacgt agaagtagat
     6781 aaatggagtg gttttgcaaa tttcttttat ttctagaagt tattcacgta tacggatttg
     6841 tttttctcac aaataaaaag gcaggaagta caatggatca tttgtatata aaatatattc
     6901 atcaattttc cgttttggtg ttaggcacac taattatagc ggggattgtc gcatttatta
     6961 ttcaaggccg tgacatatta acagtacatc aagagttttt cagttatgca tttggtattc
     7021 ctctgatcgc tataaggtct gataacaaaa agtggaagaa acgctattac attctcttgc
     7081 tatttttgtg tttttatctg ccacctaaga tttttacttt attaggtata caatgcctat
     7141 cattttcttt tatttcctat atcattgttt taattttcct cagtttcata gtatggatgt
     7201 tttatcttgt caaaaaataa atgaatgttt catgaacagt acttcatcac agcctaattt
     7261 ttttctttat gctatcgtta tattaaagaa atcaatcaga agggaaagaa agtgatgaaa
     7321 aaagttttat tagtggtaaa ccccagttca ggcggtgaac aagcaaagga atttgagcaa
     7381 ttagcgatag caaaattgga atcggtgttt gatgaagtgg tcgtcttgca tacaaaaaaa
     7441 gcaggggatg caaaaaactt tactcgcgaa gcggctacgg aagggtatca tagtgtgttt
     7501 gtcatgggcg gagatggaac agtcaacgaa ggaatcagtg gaatcgctga acaagaacat
     7561 cggccaaatt tcggattttt cccattgggt acggtgaatg acttggctcg agcattaggg
     7621 ataccgctag aacctgagga agcgatcaat catttttcga ttgaatcagt caagccattg
     7681 gatattggaa aaataaatga cgactatttt atgaatgtcg tcgcaattgg ctctatccct
     7741 gaatcaatca atgatgtaga tgcggagaag aagacgaaat ttggaaaact agcttatttc
     7801 atgtcaggaa tcaaacagtt agcttccaca caatcctact cgtttcacgt agaagttgat
     7861 ggaaagaagg aagaaattga gagcagtacc ttgctgatag gactaactaa ctcagtcggc
     7921 ggttttgaaa cattacttcc aaatgcaaaa gtggatgatg gtaagctcca tttggtttat
     7981 ttaaaagatt cttctttgat cgatacgctt aaaacattgc cagacctatt aaaaggagta
     8041 gatgaatcta cgaaaaatct agcctacctt acttgtgagc aattagttgt gtcattagct
     8101 gatgaggaag aattgacgac gaatgttgat ggagatgaag gggataaatt acctgtgaca
     8161 atcaaagtat tgccctcaca tttacaggtt tattgttaaa atggaggttg tgaccgagga
     8221 gttggcggga gaacaccgct tgttcgggat aagggactgt gacaagactt ttgtcacagc
     8281 cttttttttg tacaaaaaag aaatttacac ctaatagaaa aatttttcca taaaaataca
     8341 tattttaaat atgaaagtac aattggaaat agattaaaac gataaaataa aattgtcaaa
     8401 acgtcagaga ggatggtgga gaatgaatca atgtgtaaaa aagctgattg cgtcgatttt
     8461 gtttgtcttc cctctcttga tggtgacatc cgtttttgcc gatgtagaga aaacaaacga
     8521 atcaacgcaa tcagagaatc aaagttttga caagactact ttttcagaag aatcgattac
     8581 ttctgaaact acagaatctc aaagtgaggc ttctactaat aaaaggcaag aagaaaataa
     8641 gacaagtgag acctcagaag tagctgaaca aacgtctgat agcagtgaag cggcactggc
     8701 aagagctgtt tcagcggatg ggtacagcga agctgccaca acagaagaac tggcgcagct
     8761 tctcgcagac gaatcagtaa ctaagatccg actgattcag cctttgactt tagacaggga
     8821 attagagatc aaacgagata tcgttattga ttttggtgga ttcgctcaca atttcggcac
     8881 acaccatatt tatatcaatg agatacctca gtcgatcgag ttccagaatt ttaaaggaac
     8941 agctgcacat ccaggtggat tgacaccaaa tatcgatgga aatgccatta tcattgctta
     9001 tatgaccgat ttttggggaa gcagatatca ttttacggga gaaataaaat ttaccgggac
     9061 acttgatttg tatgatgggt ccaaattagg actgatttac gctcctcgtg caactgtcac
     9121 attagatggt gtttccggtg tgttggatgt ccaaccagtg aaggaaggac tgaatgccgc
     9181 tccgggtaaa gcctattttt gtagaagcta tcaattgaat gtgatcaatg gtagtcaact
     9241 ttatggaccg tatctaggga aattctacgg ttttctagat tcaggagatg agactggtag
     9301 tggaaaaaca gcgccaggaa tccatatctt aagcggttca aaggtctctc ttgattatga
     9361 tcgggcagat ggcgttagcg atgaaggaga ggcagtcgat acgctacctg gtaatgtcat
     9421 gtttgaagtc agtggttcgg gaagcgaatt ttcggtaaat acaaagatca atattaccaa
     9481 tgacaacaat cgcggaatca tccaaatgag aggttcagga tcgaaagtca ctgtatcgaa
     9541 tggtgggaaa atcaccatca atacagcaac tacgggcgga tttcgcttgc aaggagattc
     9601 tagtcaaatc catgtatcaa gtggtggaca aatctcggtc aaaatggctg gagatgacga
     9661 tcaacccggg aacaatggga tgcgttttgt aggaaaaggc ctttctttga tcgtagaagg
     9721 agccggatca gttatcgaca tcgataagca gagtgggcgt tccagcgcag ttcgttttga
     9781 gaatggtacg caaaagctga cagtaaccaa tggaggctca ttgagggtaa gaaatacagg
     9841 tgatggcaaa tcttacgtga acagactcaa tcaaggaaat caagcgatcc aattttatga
     9901 cgcttctggt tttctagaaa gtccaggttc agctgatttt acagtcactg gagaaaaatc
     9961 aaatatcgat atacgcgcag attccggagc aactgtagat acaactggag atattgattt
    10021 aaattttacg gcaggtgaaa aaacttattt agtcatggtc gggaaaacag gggaagataa
    10081 gaccggcatc atcagtgggg atgtgttgaa tgtggactta gaatctccta cctattttga
    10141 tttccaaaac aaacggattg gaagcgagac caatggcata ggcggctggg tattccaagg
    10201 aaatggagat tcttctttaa agatcgccca ttcagaaatc gctttatggc gaaaaacagg
    10261 cgcaacattc gataactttg aaaaagaccc ggattatttt tctgatatga cagacttatc
    10321 gatcaatggg accgacttag gcaatttcgt atcaagccct agtgcaggtt taacaaatga
    10381 atttgctcag acaggtgccg gaatgaaaaa ttataatcga atcagtgcca ataatcagct
    10441 cccgatgatt gaatccttaa gagtgccaac gaatgcagat aaaaaaatct atgggcatgt
    10501 cgttgttccc gaaggtgtcg aggcaaagcc aagagatgct tggacaggcg aagtagaagt
    10561 gactttacgt attacttacg cagatacgac gaaatcatct gtagaaatta ctgctctcac
    10621 gcaaggacaa acagatgaaa atgaaggggc aggatataac ccatggggag aaggcgaaca
    10681 aggcggcttg ttcgaagttc aagtacccaa tgatgagaga ttaaaaacgg aggatcaagt
    10741 gcaagttgtt gctgctaaaa aagtaagagg tggccaagaa gtgacagaac tggactctgc
    10801 caaaacgaca gtcgatgtga ttcctcctga acctgctaat ttaagtacca cattgatcaa
    10861 tgcagcttct cgcacgatca caggtacagg tgaagcagga gccttggttt cattgaaaaa
    10921 aaatcaagct gttttgtcag aaacaactat tgatgataca ggggaatttg ttctttctat
    10981 cccagaaaat caactttttg caggagatgt attagaaatt gtattaaacg accaagcagg
    11041 agaagctact gctaagggtg tgcagaacaa gccaagtacc aacgatgaaa ttgggaatca
    11101 caatccaagt gatacgccag ttgtttatca tgatgccccg ccttttgcac ctgctacgaa
    11161 gatcgtagta gaaggtggtc tctcatttct tgccccttcc aaactcgatt ttggtcagat
    11221 caaagcaact ggtttgacac aagaagcatt tggccaaatg gatatacagg aaaaattatg
    11281 gatttatgat cagcgagaaa cgaaaaatcc gtggatctta acgataaaat tatctcagcc
    11341 tttcacaaat gatgcaggat tttctatgca ggatgtccta tatttcaaga aaggagagga
    11401 gtatcaatta gtgaatgaag aagaactgga aattgtcaga ggacaaaatt caacgaatgt
    11461 gcaagcagat tattcagaat atttaaataa cggtcgggcg tttaaacttg tcttaaccaa
    11521 agaaaatcag atagctggta attactcagc agagataaca tggacattag cagatgcgcc
    11581 gacagaataa agatcaagga ggatgattga tgaatcgaat atggaataaa agtcatcgaa
    11641 acaactgctc tttacttatg atccttctcc ttggattcat cctttggcag acacctgtcc
    11701 atgcctccga attcaatttt gcggtagatt ttgaattacc ggctaatcag attgataaga
    11761 acaaaacata tataaatgta aggatggagc ctgggaaaat acaggaaatc ccctacacgg
    11821 tctttaaccg aacagataaa tcagtaacag ttgagacatt gatccactcc gctacgacga
    11881 attcaaacgg tgtgatcgaa tatggagaat caaaaagtaa atttgatgaa acattaagtt
    11941 atgatatgaa aaacttagca aaaacagtgg gagaaataac tgttcctcct caaagtgcgg
    12001 tcactgagac actttcactg aaagcgccag aaaaagagct ggctggtgtg gtcgcaggag
    12061 ggatcacgtt tcaagaaaaa aaagagaacg tttctaacaa aagtacagtt ggtgtcgtca
    12121 atcagttttc tcaagtgaaa gcaatcttga tttgaaatag cgaaaaagag tcttccccag
    12181 atttgaaatt aaaaaaagct tatgcggatc aaagcgatgg aagaaatgtg attaaggcga
    12241 atcttcaaaa tccaaatgct tcttatatgt tcggcttgac tacatcggtt gaaatctaca
    12301 aaaaagaaac aaaagagcct tacctttcaa taaaaaaaga aaaaatagat gtagcaccca
    12361 atacaaattt tgatttactt gtcccattag aaggaaaaaa attagctccg ggacattatc
    12421 aagcggttgt gaagggtgct tggaaagaaa aacgctggaa tctccatacc gattttgaaa
    12481 taactgatga tgcagcggac caattgaatg aaaaggatat tgatttaaaa aatcagccag
    12541 aaacatttga ctggcgatgg ctgatacttg ttggagtcat tcttattggc ttatttgctg
    12601 gattatttat tttaaaagaa agaaggaaaa agaaatgaaa aaaacaattg cattaagtac
    12661 cgttctagct ggaagtctat tattatgtac acaaagtgtt tttgctgaga ataagagctc
    12721 agccactaca gaaggaacga tttctgtgac caaaccagat gctgcaaatc ctgaagacgt
    12781 tgttccagtt cctcctgttg atccaaatga tcctgatact ccttttacac ctgacgaacc
    12841 aaatcaggga acatccggat tactgacgat tgaccaagct ccagatcttg attttggaac
    12901 aatcaagtta ggtacagcaa aaacagtata tgctgcatta caaagcggaa cggacagtac
    12961 tggagcacaa acacaagtac agaatttcgt acaagtaacg gataaaagcg gaaattatgc
    13021 cggttggaaa ttatcagtca aacgaacaga atttattggt acaacatctg atacgaataa
    13081 actaactggt tcaaaggtga aattcaaaaa cgccgtgatt cgaaatagcg caactaatag
    13141 cagtggaatg ccatctaccg tttctggaac tggcgctgaa ggaatcgaaa tcccagcaga
    13201 tcaggcagta gatctagtaa ctgcaggagc aaatgaaggg attggcacat ggatttattc
    13261 attaggagag aatgtggaac aagggagaca atcagtggaa ttatttgttc ctgtatccaa
    13321 ttatgctgta gacaactacg tttcaacatt cacatggtcg ttaacagatg ctcctacaga
    13381 agaggaagcg taaaatcata tcaacgattt cagggagtgg agccgattca aggcccactc
    13441 cctgaaatct gctatgctta cgtctcagct cttattcatc aactcgaagc agttttttgg
    13501 aagtcatgga aacgttcctt tgtcttttca aagatctttc gaccaacgag taaggagtca
    13561 ccgttgaaaa attctaacac ataatgagca gaatcaattt tctgcaattg cgataagttg
    13621 atacagtaag attttaaaag taaaaatttt aggttatcgc tgaaagcccc ggaaatacgg
    13681 gcatttcgca ggatatgaga actcaattta ctaccaattt actactttcg gattgagccg
    13741 catatatgct gaaccatact gctaataccc gccaccccaa atacggcaca tcataaattg
    13801 aatacgacac cgtaaacgcg gcgttcctct ttcccgtcat gggagaacag gacgccgctt
    13861 ttttatgccc aaatagagaa aggaggcgac gccatgctat ttacttccgg ccctgaccgg
    13921 gcgtttgaac ggctgatgca ggaaaagccc ggtttcgatc actacgacgg cggcggggcg
    13981 gacgcgccgg aggattgcgg cacctgccga ttttaccgcc cggattggaa atatcaattc
    14041 tgccagtttg cagagtgtcc ctatcagccg ggcaagctga ccgactatgc agcggtcaaa
    14101 ttcacagtga aaggagcgaa caacgctatg gcagttttcc gtgtggaaaa gaacaaaggc
    14161 tatacggtga tgtcaaatca ccacctgcgg aataagaacc tgaccttaaa ggccaagggc
    14221 ctgctgtcgc agatgttgtc cttgccggag gattgggact ataccctaaa aggactgtcc
    14281 tatatcaacc gggaaagcat cgacgcgatc aggacagcgg tatgggagct tgaaaaagct
    14341 ggatatatcc ggcgtgagca gggccgtgac gcaaaaggca aaatggccga tatggtctat
    14401 accatctacg aacagccggt attggaaaac ccggtattgg aaaatccaac atcggataac
    14461 ccggtgttgg aaaatccgac atcggataat ccggcgtcgg aaaatccaac gcaattaaat
    14521 aaagaagtac aaagaactga cttatcaaaa aaagaaaaaa taattacaga tggacaaagt
    14581 acccattcca ttcctatccc atccccgacc cctgccccta tggagggcga ggcagcggct
    14641 acgccgccgg aacggaaaag gacaggaaag gatgaggctg tacggattta tcgggaaatc
    14701 attttggaga acatcgagta tgcctatctc attcaggaca ggagcattga ccgtgaacag
    14761 cttgacgaaa tcgtagacct gatgctggaa accgtctgca ccgcccgaaa gacaatccgt
    14821 gtcgccgggg acgactaccc tgccgagctg gtgaaatcca agtacatgaa gctgaccggc
    14881 gaacatatcc gctttgtcct tgactgtctg cgggagaaca caacgaaagt ccgcaatatc
    14941 aaacaatacc tgcgggctat gctgttcaac gcccccagca ccatttccaa ctactacacg
    15001 gcccttgtcg cgcacgacat ggcacagccc gattggggaa agcctaaatc cggcctgccg
    15061 gactattcct gcggcgaggg cgaaagcctg taacgagaaa aggaggacga ccctatgaag
    15121 cagggcgcat tgatttttga cgagcgaaca gaccgttacg acatccgctt tgatctggcc
    15181 gactattacg gcggcctgca ttgcggggag tgtttcgacg tgatgatcgg cggcaaatgg
    15241 aggcccaccc gcattgaaat ggccgaaaac tggtatcttg tcggcatccg ggccgacgac
    15301 ctttccggcc tgcgggtgcg gatttgacct atatctacct gcggcgtctg gtggttccgc
    15361 cttagacgcc gcttttgact ttctgacaag gagggatgcg attgcaggaa gaagttactc
    15421 aaaagaccat tgccctgtcc atgaaaacgg gcaagctcac ggctcaagtg ctgcaagcgg
    15481 cgctgaaaaa gtacctgcaa caccgggcca agggcaaaaa cacgctgcac cacggccagc
    15541 agagcctaaa gcagcttaaa aagcatgggg ctgatctctc caacattgag atcaccgagg
    15601 ccaacattgg agcgttcaag ccatgcgcca agaaatacgg cgtggatttt accttacgaa
    15661 aagataagac cacccagccg ccccactacg ttgtgatttt caaggccaag gatgcagata
    15721 accttgatct ggcgtttcgg gagtttaccg ccaagacgct ttccaaggag cagcggccct
    15781 ctatccgcaa ggttttgtcc gctgtgaagc aaaaggcggc ggcccagacc aagcagcggg
    15841 ccaaggagaa aatcaaggaa agggggctgg aactgtgaag cctgacgtaa agaaattgct
    15901 gatcctgaac ctcccgtatc tgatttttgt gtacctgttt gcgaaatgcg gggaggcgta
    15961 ccggctggcc gctggtgctg acctgtcggg gaagctcctg cattttgcgg atggttttgc
    16021 ggcggctttt gccaacccgc tgccaagcct gcacctgttt gacctgtgta tcggtatcgc
    16081 cggtgccgtg atcgtgcggc tggtggtgta ctgcaagagc aagaacgtga agaaataccg
    16141 caaaggcatg gagtatggca gcgcccgctg ggggacggcc aaagacatag cgccttacat
    16201 cgaccccaag tttgaaaata atatcctgct cacccaaacg gaacggctta ccatgaccgg
    16261 caggcccaaa gaccccaaga cagcgcggaa taaaaacgtg ctggtgatcg gtggcagcgg
    16321 ttcagggaaa acgagatttt tcgtgaaacc caacctgatg caatgctttc cgaccacgga
    16381 ctatccgact tcgtttgtgg tgacagatcc gaaaggcact ttggttctgg aaaccggcag
    16441 gatgttccag caggcgggct accgcattaa aatcctgaat accattaact tttccaagtc
    16501 catgaagtac aacccctttg tctacatcca ttcggaaaag gacgtgctaa agctggtaaa
    16561 taccctgatt tccaacacca agggcgaggg ggaaaagtca gcggaggatt tttgggtgaa
    16621 gtcggaacgg ttgttttatt cggccctgat cggctatatc tggtacgagg ccccagcgga
    16681 ggaaatgaac ttctcaacgc tgctggaaat gataaacgcc agtgaagccc gcgaggacga
    16741 cccggagttt caaagccccg tcgatctcat gtttgagcgt ttggagcaga aagaccccga
    16801 ccattttgcg gtgcgccagt acaagaaatt cctgctgtcc gcaggcaaga cccgttcttc
    16861 catcctgatt tcatgcggtg ccagacttgc gccctttgac atccgggagg tacgcgagct
    16921 gatggaggac gacgaaatgg agctggacac catcggggac gaaaagacgg tgctgtatct
    16981 cattatgagc gatacggaca cgacctttaa tttcattctg gctatgctcc aaagccagct
    17041 aatcaacctg ctttgtgacc gggctgatga tgtgtacggc gggcggctgc ctgtccatgt
    17101 acgcctgatt ttggatgaat ttgccaacat tggccaaata cccaatttcg ataaactcat
    17161 tgccaccatt cgaagccgtg aaatatcggc ctctattatt ttgcagagcc agtcgcagtt
    17221 aaaagcgatt tacaaggacg ccgccgagat catttcggat aactgcgata gtgtgctttt
    17281 ccttagtggg cgcggcaaaa atgccaagga gatttccgat gcgctgggga aagaaacgat
    17341 tgacagtttc aacaccagcg agaaccgggg aagccaaacg tcccacggat tgaactatca
    17401 aaaattagga aaggagttga tgtcccaaga cgaaattgcc gtgatggacg gcggcaagtg
    17461 tatcttgcag ctacggggtg tgcgcccgtt tttatcggag aaattcgata ttaccaagca
    17521 tccccggtac aaataccttg ccgacgccga caagaagaat acctttgacg tggacagatt
    17581 tttgactatc acgcgccgga aacggcagca agtggtaacg caggatgaag tattcgacct
    17641 gtatgaaatc gacctgtcgg acgaggacgc cgccgctgaa taaacagcgg cttttttcat
    17701 tccaacaaca aaatcaaaaa atcattatga gccggaaacc ggcagaaaga ggtaaattta
    17761 tggcattttt taattccgca gttactactt tgcagactat cgtgatcgga ctgggcggcg
    17821 ctctgtgcgt atggggcggc atcaatctgt tggagggata cgggcaggac aatccggggg
    17881 caaaatcgca gggtgtcaag cagcttgtcg ctggcggcgg cgtggccctg atcggtgtca
    17941 ctctggttcc cctgctgtcc gggctgctgg gctgatcctg gcctttgtcc ctgtccaaac
    18001 ccttaactaa tcgcctccgc gtcctcccgg ccagaccggg agggcgcggg aaaggaggtg
    18061 ctacccgtga ttagtgaaat cattgaagaa tggataaaag gcatcctcat ggacggtatc
    18121 acgggcaacc tgtccgggct gttcgatacg gtaaatgcca aagtcggaga aatcgccgcc
    18181 gacgtgggac gaaccccgca ggcatggaac agcggtattt tcaatatgct gcacagcctg
    18241 tcggaaaccg tgatcgtccc catagccggg gccatactcg cccttgtcat gtgctatgag
    18301 cttatccaga tgataacgga aaagaacaat atgcacgact ttgacagctc catgttcttc
    18361 cgctggatat tcaaatccgc gtttgcaatc ctgatcgtaa cgaacacatg gaacatcgtc
    18421 atgggcgtat tcgacgccac ccaaagcgtc gtcaatcaaa gcgccggtgt gattatcggg
    18481 cagacatcca ttgattttaa caccctgata ccagaccttg aaagccaatt ggaggctatg
    18541 agcgtgggcg ctcttttggg gctgtggttc caaacccttg ttgtgggcct caccatgaat
    18601 atcctttcca tctgcatttt ccttgtgacc tatggccgca tggtggaaat ctatgttgtc
    18661 acgtcgctgg ggcctatccc ccttgccaca atgggcaacg cggaatggcg cggcatgggc
    18721 caagggtatc tgaaatccct gctggcgctg ggcttccaag cctttttaat catggttgtg
    18781 gtgggtatct acgcggtgct gatacagaat atcggttccg cttccgacat atccggcgca
    18841 atctggggct gtatgggcta tacggtgctg ctgtgcttct gcctgttcaa gaccggcagt
    18901 atatcaaagg ccgtattcgg ggcgcattga tcccaaaatc caagcataca caggaggaac
    18961 ttgtttattt caacgtacaa catcatttac gctgacccgc cgtggcggta tgactgcaaa
    19021 aacgtacagg gcgcagcgga aaatcactat tccaccatga gcattgacga gctgtgcgcc
    19081 ctgccggtgg aacggctggc gtccaaagac tgcctgctgt ttttgtgggc cacattcccc
    19141 atgctgccgg aagctctgcg gttaatcaaa gcgtggggct tttcattcaa gaccgtggct
    19201 tttgtatggc tgaaacagaa ccgtaaaagc cttacatggt tttacgggct gggccgctgg
    19261 acaaggggaa acgcggaaat ctgcctgctg gcaacacacg gcaagccgaa gcgtcgttct
    19321 gcctctgtcc atcagtttat tatcagcccg attgaacaac acagcaaaaa gccggatgtg
    19381 acccgtgaaa aaatcgtaga gctggcgggc gatttgcccc gcgtggagct gtttgccaga
    19441 cagaaaaccc ccggctggga cgtgtggggg aacgaggtgg aatgtgacct tatcctgacg
    19501 tgaaaggagg tgccaaatgg cttatgtaac cgtccccaag gacttaaccc atgtgaaaag
    19561 caaggttgtg tttgggctta ccaaacggca actgatctgt ttttccgggg cgctggtgat
    19621 cggcgtcccc ttatattttc tcacccgtga ctatcttacc aacagcgcgg cggccctgct
    19681 catggtattt gccatgctgc cgggcttttt gcttgccatg tacgagcgtc acggccagcc
    19741 ccttgaagtg gtgattatgc agatcatcca gtgctgcttc atccagccaa aggagcgtcc
    19801 ctatcagacc gacaacacct acaccgccct tgtgcggcaa taccagatgg aacaggaggt
    19861 aaaggccatt gtccaaaaag gaaatcccaa gagaaaccga aaaaacaaag ctgacccgcg
    19921 cccagcgaaa agaaattgac gcggtaatcc gtaaatataa gggcgacggc aggccccaca
    19981 cggcgcagca gagcatcccc tacgaggtca tgtacccgga cggcgtgtgc cgggtatcgc
    20041 ccggcgtctt ttccaagtgc attgagtttg cggacatcag ctatcagctt gcccagccgg
    20101 acacgcagac ggctatcttt gaaaaactgt gcgacctgta taactatgtg gacgcctcca
    20161 ttcatatcca gttttctttc ctcaatcgga aagttgaccc ggtgcagtac gccaagagct
    20221 ttgagatcgc gccgcagggg gacgacttcg acgacatccg ggccgagtac accggcattc
    20281 tgcaaaagca gcttgcaaac ggcaacaacg gcatggtaaa gaccaaatac ctgacattca
    20341 ccatcgaggc cgaaagcgtg aaagcggcgc gagccagatt gaagcgcatc ggctttgacc
    20401 tgttaggcta tttcaagagc atgggggccg tagcccatgt gatggacggc tgggaacggc
    20461 tgaacctgct gcatggcgtg taccacccgg acggcgagat attcaatttt gactggaagt
    20521 ggctggcccc gtccggcctc tccaccaagg attttattgc cccgtcctcc ctgtgcttcg
    20581 gcaatgcaaa gacattcggc atgggcggca aatacggcgc ggtaagtttc ctgcaaatcc
    20641 tgtccccgga gctgtcggac gatatgctgg ccgacttcct caatacggaa agcggtgttt
    20701 tagtcaatct ccatgtgcag gccattgaac agaccaaggc gatcaagacc atcaagcgca
    20761 aaattaccga ccttgacgct atgaagattg cggagcagaa aaaggccgtc cgcagcggtt
    20821 acgatatgga cattcttccc agcgaccttg ccacctacgg cgaggacgcc aagaagctgc
    20881 tgacaaagtt gcagacccgc aatgaacggc tgttccagtt gacgttcctt gtcctcaacg
    20941 tggccgacac caagcaaaag ctgaataacg acgtgttcca agccgcaggc gtggcccaaa
    21001 agcataactg tccccttgtc cggctggact accagcagga acagggcctt gcaagcagcc
    21061 tgccgctggg cgtcaatcag atcaagatac agcgcagcct tacgacttcc agcgtggccg
    21121 tgttcgtccc ctttgtgacg caggagcttt ttcagggcgg cgcggccatg tattacggca
    21181 tcaacgccaa gtcccgcaac atgattatgc tggacaggaa gcaggcccgt tgccccaatg
    21241 ccttgaagct cggcaccccc ggcagcggca aatccatgag ctgtaaatcc gagatcgtca
    21301 gtgtgttctt aacgacgcct gacgatattt ttatttcaga cccggaggcc gaatattacc
    21361 cccttgtcaa acggctccac ggacaggtaa tccggctgtc gcctaccagc aaggactttg
    21421 tgaacccgct ggacatcaac ctgaattatt cggaggacga taacccgctg gccctgaaat
    21481 ccgactttgt gctgtcgttc tgtgagcttg tcatgggcgg caagaacggg ctggaagcca
    21541 ttgaaaagac cgtgatagac cgggctgtgc gcgtgatcta ccggccctat ctggcagacc
    21601 cccgcccgga gaatatgccg atcctgtccg acctccacaa agcgttgtta gatcagcatg
    21661 tcccggaggc tgaccgggtg gcgcaggccc ttgacctgta tgtgtccggc tccctgaacg
    21721 tatttaacca ccgtaccaac gtggacatcg gcaaccggct tgtgtccttt gacattaagg
    21781 agctgggcaa gcagctcaaa aagctgggga tgctcattgt ccaagaccag atatgggggc
    21841 gcgtcacggc caaccgaagc caaggaaagg ccacatggta ttttgccgac gagttccatt
    21901 tgcttttgaa agaggaacag acggcggcct attctgcgga gatttggaag cggtttagga
    21961 aatggggcgg cattccaaca ggtgccaccc agaacgtcaa agacctgctt tcctccccgg
    22021 aaattgaaaa tatccttgaa aacagcgact tcattacgct gctcaatcag gcgtccgggg
    22081 atagaaaaat ccttgcggaa cgcttgaatt tgtccaccga acagcagaag tacatcgaca
    22141 attccgaacc cggcgagggc cttttgatct ttgaaaacgt ggtgctgccc tttaccaacc
    22201 ccatcccgca caacacccag ctttacaaga ttatgacgac ccgcttaaac gaggtggcgg
    22261 gagtatgacc cggcgacgcc acaaaggagg tgaaccacca tgaaagagct gaaagccaag
    22321 gcgaaagtga cgcaggccat gacccgcgac gggctgacgc tggaaaatca ggccaccggc
    22381 gaggtggaga acatttccag ccgggaggcc gaacaggatt tgtccgcgcc ggggccgggc
    22441 ggcaccgccg ataagctgct ggaacgggcc gacgccatcc atgacggcca taaggccaag
    22501 aaagccgcga agcaggccgg ggctgtggcc gccgaggggg acgctgccct gcaccggcca
    22561 tccgcccggc tccaactgtc ggaggaagaa cgggccgacc cggatttaca gccctatatc
    22621 cgaaaatcgg acaaacgggc cgataagctg gataaggccc gcgccgccat ccccaagaag
    22681 cgcgtcccgg tcaaggaaac cgtctttgac gaggcaagcg gcaaagcaaa gaccgtcctg
    22741 cactttgaca aacaggacaa ggggcctccc tccctgaaac ccaatccggc aggccgtcct
    22801 gtttccgagg tttttctatt cggccacggg aaaatccatg aagtcgagca tgaaaacgtg
    22861 ggtgtggagg gcggccataa gggggaggaa cttgccgagc ggcaggccgg aaaagccatc
    22921 cgcagcacca tccggcacca caggctgaaa ccctactggg acgcggaaaa ggccgagcgc
    22981 aggctattgt ctgccaacgc ggagtatttc taccagaaat ctttgcggga taacccggag
    23041 atcgcacagg cggccagcaa ccccatttcc cggttctggc agaaacagca gatcaagcgc
    23101 cagtacgcca aggccgcccg gacagcgggc cagaccgcag gcgcggcggc acagggcgcg
    23161 gccaagacag ccggggcctc cacgaaagcg gccaaggccg cagccaaaga aagtgaacgg
    23221 gcggcctcct ttgtggcccg ccactggaaa ggggcgctgg ccgtccttgt gttggggctt
    23281 ttgatgctgc ttatcatcgg cggcttacag tcctgcaccg ccatgttcgg cagcgccgga
    23341 agcggcatca cggcgtcctc ttacttttcc gaggatagcg atatgttggc cgccgaggac
    23401 gcctacgcgg agctggaagc cgagctgcaa gactatctgg acaactacga ggccacccat
    23461 gactatgacg aataccattt tgaccttgac gagatcagcc atgaccccta tgtgctgatt
    23521 tccattctgt cggcgctcca tgacgggata tttaccatcg gggaggtaca gggtgatttg
    23581 tccatgctct ttgacaagca atatatcctg acagaaaacg tcgtggtaga aacccgttac
    23641 cgcaccgaaa ccgatacatg gacggacgcg gagggcaaca cccatacaga cacctaccaa
    23701 gtgccgtatg actattacat ctgctacgtc acgctggaaa acttcgacct gtcccatgtg
    23761 ccagtctata tcatggacga ggaaacgcta agtttctatt ccctgtatat gtccacgcta
    23821 ggaaaccggc ctgatctgtt ttccggcagc cagtacccca acgcctccac cctgacgccg
    23881 ccgacctact acgacgtacc cccggaggct ttggaggatg ccacctttgc cgccatgctc
    23941 aaagaggcgg aaaaatatat cggttatccc tatgtgtggg gcggcagctc tcccagcacc
    24001 agctttgatt gcagcggctt catttcgtgg gtaatcaatc atagtggatg gaacgtggga
    24061 cggctggggg cgcagggcct atataacatc tgcacccctg tttccagttc gcaggccaag
    24121 cccggcgacc ttgtattttt caagggaacc tacgacaccc ccggcgtgtc ccacgtcggc
    24181 ctgtatgtgg gcaacaatgt gatgctgcat tgcgggaacc cgatttccta cacgaacctt
    24241 acttcaaact actggcaatc ccatttttac agttacgggc gtttacctta acgccagaaa
    24301 ggagctttca attatggcaa ccaaacttga ccgcatcgaa aaggacatcc agaaaaccaa
    24361 gtctaagatc gcggagtttc agaaacagct tcgggagctg gaaacgcaga aaaccgaaca
    24421 ggagaatttg cagatcatcc agcttgtgcg cggcatgaac atgaagccgg aggaatttgc
    24481 cgcgttctta cgcagcggcg caatgcaggc cgcccctgcc gcaacccctt accatgaaca
    24541 ggaggacaat gcccatgaag aataagacca gacggatttc ccgtattctc cccgcacttc
    24601 tggccgtgat gctctgcgtc acggcctttc ccgttaccgc ccttgcaggc ggcaatgacc
    24661 cggcaccggc cccgctgccg gaggctacaa ccgaacccgc tacgggcggt ttggagcctg
    24721 aaacagacga aaccggcacc gccacggacg ggacagaaac cgaggccgaa aaagataccg
    24781 gccctctgac cggcaaggac atcaccgacc tgttttccgc gctgttcggt tccaaggtga
    24841 gcattgccgc cacggacgac ggcatccaga tcaccaccgg caccgacaaa aaagaacctg
    24901 aacagaccgg caccgtcacc accaacggcg gcaggctgaa tgtccgcacc ggcgcggggc
    24961 ttgacaagac cgcgttcacc cagcttccca atgggacgac ggttgaggta gtcggcacag
    25021 acggcgactg gattaaaatt ctcttgccgg agcgcatcgg ctatgtccat tccgactata
    25081 tgaccgtcag cgaaaaggaa gtagcggcta ccggcgaggg cggtttttcc ctctccattg
    25141 acccggagga aattgcttct ctgctggaac tgttcaatgg cggcggggcc agcgccgccc
    25201 tgtccccgga cgggaacctg tcactgattg acgacatcgg cagcgccgcg aaaaatggca
    25261 agcagtttat caccgtggaa accaaaaacg gcaatgtgtt ttatctgatt attgaccggg
    25321 acgacgaggg aaaagaaact gtccatttct taaatcaggt ggatgaagcc gatctgctga
    25381 cgctgatgga ggacggggaa accgtcaccc ccgctgctgt ctgctcctgt accacgaaat
    25441 gcaaggccgg ggctgtgaac acgaattgcc cggtatgtaa aaccaacctg accgagtgca
    25501 gcggcccgga gccgcaggaa ccccagccgg aggaacccga agccccggag gaagaaccca
    25561 agggcggcgc gggcggcctg atcgtgttcc tgctggtggc gctggcgggc ggcggtgcgg
    25621 ccctttacta tttcaagttc aaaaagccca aggctgaaac caccggcagc gacgatttgg
    25681 gcgagtatga ttttggggag gacgaggatt tggaggacga ggaacccgaa accgagtttg
    25741 acccggaagc tgattttgtg agtgaacagg aggacgagga atgacatata aacttgtaat
    25801 cgcggaaaaa cccagcgtgg cccgcagcat tgcgggcgtg atcggggcca cggagaaaca
    25861 cgacggctat ttggagggga acggctatct ggtgagctgg tgcatcggac atctggtgtc
    25921 ctttgccgac gccggacgct atgacgagcg tttcaaaaaa tggcgctatg aggatttgcc
    25981 cattctcccg gaaacatggc agtacatcgt ccccgacgac aagaaacagc agtttgacgt
    26041 tctctgttcg ctgatgcagc gccccgacgt gaccggcctt gtgtgcgcca ccgacgccgg
    26101 gcgcgagggg gaattgattt tccgtttcgt ctaccagatg gcgggatgcc aaaagccctt
    26161 tgagcgcctt tggatttcct ctatggagga cagtgctatt aaggacggct ttgcccacct
    26221 gaaaccgggc ggcgactatg atccgctgta tcaatcggcc ctgtgccggg ccaaggccga
    26281 ctggctgatc ggcattaacg ccacccggct tttttccgtc ctgtaccaca agaacctgac
    26341 tgtgggccgc gtccagacgc cgaccttaaa aatgctggtg gacagggacg ccaagattac
    26401 cgatttcaag aaagagaaat atcacatcgt ccatatcacg gcgggcggcg cggacgcggt
    26461 aagcagccgc ttttccgacg ctgccgaggc aaacaccgtc aaggcggctt gtgcaaaagc
    26521 gcaggccgtt tgcgtttccg tgacgcggga gaaaaagacg gaacagccgc ccaagctcta
    26581 tgaccttacc accttgcagc gggaggctaa ccggcttttc ggctataccg ccaagcagac
    26641 ccttgactat gcccaggcac tgtatctaaa gaagctgctg acctatccga gaacggatag
    26701 tcaatatctt accgacgata tgctgcccgc cgtggaaagc cttgtgtccg gcctgtggga
    26761 gctggtgccg tttgccaagg gcctgaacct ttccccgcag tttgaccgca tcctgaacag
    26821 caaaaaggtg tccgaccacc acgccattat ccccaccgct gaatttgtga agcagggctt
    26881 tggcactctg gccgagagtg aaaaaaagct gctgtccctg atctgctgca agctcttatg
    26941 tgccgtggcc gggccgcata tctatgaggc cgtcaccgcc acatttacct gtgccgggca
    27001 ggagtttacc gccaagggca agaccgtcct ttcccccggc tggaaagaga ttgaacgccg
    27061 gttccgttct tccttaaaga ccgacgccga cgaggacgcc gaggcggtgc gggagctgcc
    27121 ggagctttgc gagggccaga cctttgcaga cgtggccgcc tctgtcaccg agcatttcac
    27181 cacgccgccc aagccctaca ccgaagatac gcttttgtcc gctatggaac gggccggggc
    27241 cgaggatatg ccggaggatg ccgagcgcaa gggattaggc acaccggcca cccgcgccgc
    27301 cattctggaa aagctggtgc agatgggctt tgtccagaga aaaggcaagc agctcattcc
    27361 caccaaggac ggcatcaatc tggctgtggt gctgccggag gcgcttactt ctccccagct
    27421 tactgccgaa tgggaaaacc ggctgaccga gatcgccaag gggcaggccg atcctgacga
    27481 atttatggac ggcatcgaga cgcaggcgcg ggagctggtg cagacctatt cctgtatcag
    27541 tgaggaaaag cagaaattgt ttcaggccga gcgtgttcct atcgggacgt gtccccgctg
    27601 tggtgaggct gtctatgagg gcaagaaaaa ctactactgc ggaaaccggg cctgccagtt
    27661 cgtcatgtgg aagaatgacc gattttttga ggaacgcaag aaagcgttca ccccgaagat
    27721 cgccgctgcg ctgctcaaaa ccggcaaagt caaggtaaag ggcctctatt ccgtaaagac
    27781 cggcaaaacc tacgacggga cggtgctttt ggctgatacc gggggcaagt acgtcaacta
    27841 ccgcattgaa cacaggagct aaaggacagt aacacagcaa gcatagggag tgtggctaca
    27901 ctcccggtaa aatcccccgg ccgcgtccct gccgggccgg ggatttttgc ttgttgggga
    27961 agtccccaac cccctatttt ttgaaacaga acagagaaag gagtgaccgc gtgaacgaag
    28021 tattttctat ccaagtccat aaccggcagt ttttggaaca gggcaaacaa ggcgtctggc
    28081 tggatttgcc caccacaacc gaaacgctgc aagccgccct gcgggatgtt ggcattactg
    28141 ccgacaatcc gcaggatttt tttatcaacg ggtattcctg cccggaggac agacaccttg
    28201 ccattcccta tgacatggtg ctggccgccg acgtggacga gctgaatttc cttgccgccc
    28261 ggctgggcca gcttgacgcc gccgagatcg cagagctgaa cgccgccctg caaaatcccc
    28321 gtggcggctt tgagaatatc ggccagatca tcgactacac cgaaaatgtg gattactatg
    28381 tgcatcttcc cgacgttagg ggggatggac agttgggcga ctactacctg aaccgttccg
    28441 gcatggtgga tatgccggag gaatggaaag ccgggattga tacggcgcag tttggacgcc
    28501 acattgccca gcaggaacaa ggcgttttta cccagtacgg ctatctggtg agaagcggcg
    28561 acgaatggca gcgcgtccat gagggccagc cggtgccgga ggaataccgg gtgatgcact
    28621 acccccagcc ggaagctgac cgggaggaac cgcaggccca gcagccggag gcatccgaaa
    28681 gccccgacaa agcgccgccc ccggttatcc cgatcatgct ggacggcatg aacagcaaag
    28741 aacgcatgaa agtgattact gaccgtctgg aaaccggcgt acaggagctt tttgaaagta
    28801 gccgctatat ggcttactta tccgctatgt ccaagatgca cgattacagt ctgaacaata
    28861 cgctgctgat cgccatgcag ggcggttcga ttgtggcggg ctataacagg tggcaggatg
    28921 aatttgaccg ccatgtgaag cggggcgaga aaggcattaa gatactggcc ccggccccgt
    28981 tcaaggttaa gcagcagatg gagaaaatcg acccggccac ccagcagccc gtgatcggcg
    29041 cggacggcaa gcccgtgacc gaagaacagg aagtgacggt tccggccttt aaggtggtga
    29101 cagtctttga catcagccag accgagggca aggattttcc catgccctat atcagtgaac
    29161 ttaccggcga cgtgcagcag tatcaggatt tctttgccgc gctggaacgg acatcaccct
    29221 atcccataag cattgagccg atttcagacg gggccaaggg ccgctgcttc tacgcaaaac
    29281 agcgcattgc catcaacgag ggcatgagcg aattgcagac cctaaagacc gccatccatg
    29341 agattgccca tgccaagctc cacgccattg accgggaggc ccccgccgag gaacaggcgg
    29401 cccggccaga ccgcagcacc cgcgaggtac aggccgaaag cgtggcctat accgtctgcc
    29461 agtattacgg gctggacacg tcggactatt cttttggcta tgtggccgat tggagcagcg
    29521 gcagggagtt atccgagctg aaagcctccc ttgaaaccat ccgggccacg gccagcgaat
    29581 tgataaccga gatcgacggc cattttgccc agcttcagca ggagcgcgag gcccggcagg
    29641 aacaggaggc cgtcacggtt gacgttaccc cggaggcagc ggccccggcg caggccgagg
    29701 aagaacaggc cccggccctt gatccggcag ccgagccgct tgtgactgtg ctatggagcg
    29761 aaagccccca gctaaaggac ggccagcaaa tgccgttgca tgaggccgac gcgctgtttg
    29821 cccgtctgga tgcagcatat ccggcagagg caggctatga caaaaccgcg ttccgcattg
    29881 actgtatctt tcagggcgag ccggacagct acgaggggcg gcaggatttt ggagataggg
    29941 acggttccct gatcgaacat atccagagct accaccaatt ttacgcgcag gacgaaaact
    30001 ggaaaaagca tgtaatcgct acaaccggca tagagggctg ggagcaggac aaggcccatc
    30061 gggatatgct gttaggcgag tttgtcccct atatgaagct gcattgcagc cttgcccaaa
    30121 tggaacagac ggcgcagggc cgcttacagt ccggggaaac cctgacgccg gaggaaacgg
    30181 cctatttggg ggcgcttctc tcttatgtgc aggagtgccg ccccatgctc aatcagggcc
    30241 agtatcagtt gccggagccg ccgaaactgg ctgacttcga ccagagcttg caggactaca
    30301 aagcacaggt acaggccgag atcgcgcagg aggccgccgc agccggtatg accgtggagg
    30361 aatacgcggc ggctggctat gaagcacccc aacaggacac cttttccatc taccagcttc
    30421 gaggcgggga ggaaacccgc gactatcggt ttgagccata cgagcgttta caggccgcag
    30481 ggctggccgt ggacagtgcc aactatgacc ttgtttatac ggcaccgctg gataaaagca
    30541 cgtctttgga ggatatttac cgcacattca acatcgacca cccggcagat tttaggggac
    30601 acagcctttc cgtttccgac gtggtggtgc tgcaccagaa tggacaggac accgcccact
    30661 atgtagacag cttcggctat atggaagtgc cggagttttt gcgggaaaat cccctgcgta
    30721 ccgccgaact gtctacggag cagaacgaaa acatgattga cggcattatc aacaatacgc
    30781 cgcccgaacc gcagccggag gaacccgaac agctatcttt tgaggatgtg gcagttgctt
    30841 ccggccagac acaggaggaa cccccggagg ctgcgccccc gcaaacggct gtccgctatt
    30901 atcccatcaa tgagggagcc gcccgccgcg ccaaggaagc catgagcttt tctgactacc
    30961 ggcccggcag cgccacggcg gaataccggc actatgtcga tcaggccgtg gaaattgcgg
    31021 agcgccagaa aaagcgtgtg gagccagagt atcacgaaaa gatagacagc ctccttgaca
    31081 cctacgcccg caagctggcc gagaacatga ataagggcta tgagattacc gcccgcgtcc
    31141 cctctgtcct gattgccggg ccgtccaatt tcccggtacg ggcgaaagaa aagcagaacg
    31201 ccgccagtga ccgcaacatg gaggaatttc agtacattca gggcttgctt gacaaaatcc
    31261 gcagcaccgg catgggtggt atcagcgccg acgatccgca ggccgtttcc aagctggaaa
    31321 agaaactgga aaagctggaa gcgtcgcagg agttgatgaa ggccgtcaat gcctactacc
    31381 gcaagcatgg gacgctggac ggatgccccc atctgaccga aagaggcatt gaaaacctga
    31441 aagcggatat ggcgtcgggc tggcactatg agaaaaaacc gttccagtcc tggcagctct
    31501 ccaacaataa cgccgagata cgccggttaa agggccgcat tgaggaattg acccgccaaa
    31561 aggaggcggc ctatgtggga tgggagtttg acggcggcac tgtggagatc aaccgggtgg
    31621 ccaaccgcct gcaaatcttc tttgagggga agccggatgc tgctgtacgc gacgagctga
    31681 aaagcaacgg tttccgctgg tcgcccaagg ccggggcatg gcagcggcag ttaaacgaca
    31741 ccacaatccg cgtcgctgac cgtatcaagt gcatccagcc cctttccggc gaaaagccca
    31801 gcgccttaca gcttgcggcc cgcagggaga aagaaaagcc ctctatccgg gcgcagctca
    31861 acgcggccaa gaccgaacag gccaagcagc caccggcgcg ggaaaaatca aagggattgg
    31921 aggtagagta aatgcagaag tttgaaaatg tggacgttct ggccgcgctg gaacagatca
    31981 tgcggcagaa caccgcgttt tatcaaagtg actttggcat tgacaaagac attatcaggc
    32041 gggatgccgc cagcgatcag gccgcagaca agaccctgct ctggatgtcc cggccctccg
    32101 ggacgtactg tttccgggaa cgtgatgttt tcctgaaaga cacccgacag tacaacacat
    32161 ggaaatttta cggggagcag acccgtgaca agatactggc ctacgcggtg gagctgaccg
    32221 gcacacaggg cggcactatc cggggcaatc tctatgagct ggactatccg cagcatttcc
    32281 ggcacgtcat tgaaaccgcc cagccggtga gtgtgaaccg gctcttttat gagcatggca
    32341 cccgtgacat cccggagagc cagcgttttg acggaagccc tgaccgggta ttgggaaact
    32401 ttttgtacta tgaggcccag ccccatgacc cggctgtgct gcaggaggcg ctacggacgg
    32461 agcagcacag ccgggggcgg gccgtccccg gcgatttcaa agtccacgtc accgctttgc
    32521 atgacagccg gattgaaacc gaggcccggc gtattgtgga cagcctgaaa gatctgtccg
    32581 cgcctaacag ccccaataaa acgcatttca tggtggagat ctccccgcac tttgcggcga
    32641 ttgcttccac caaggataat gaccggctct ttgccatgct gccctataaa tccctgtgtt
    32701 ttaccgggat gaaaggcagg catggcgtgt atgccgtgat taaccgggac gagcgccggg
    32761 atgtgagtat tcgcaggccc cggccctcta tccgcaagca gctatccgac agcaaacagg
    32821 ccgccagccc aaaaaaggcg gcggccagaa ccaaaaagaa tgaattggag gtataaggaa
    32881 tgatgcactt taccgtggag gaagaaaacc tgatctgtat gtaccacaat gcagaccggc
    32941 gcagaacgat aaacaggctc accgccgtca tgccggttat ggatggggat atgcgggcgc
    33001 aggcccagca gaccctttcc aagctggaac gcatgacgga tgccgactat gacggccaga
    33061 agttccactt cacagacgaa taacgaacag cagacgccgg gcgcggcggc catgtggtcg
    33121 cttgcgtccg gcgtcttttc tttttgccta ttcctacgca tttagaaccc ggtattgtcg
    33181 gggataggat gaagtattcg cttgcccctg caaacatgcg ggagaagcct tgcagcgggc
    33241 ggttttcaat cccttaaatg cgtaggttgc agctataatt agacccctga aacagatata
    33301 gccgcgcagc gggtgtatct gtttcagggg tgtgcaggtg atagccgcaa agcggcgtaa
    33361 gagggtgcag ccctcttgcc gtctatctct gttccagcgg gaagctcggc aatgcttcca
    33421 gcagtttcag ggaaatgcgc tgccgtatat cttcgtcaat gactttcttc tttttgccgt
    33481 ttgcctgtct gatctccacc gtggaaagct cgttgatgta gtcagcataa tgggccaaca
    33541 ctttttccgt ggcccacctc tcaccggcaa cggcggcttt gatcgtttca tagtccagca
    33601 gcttttcttg tccgtccatc ctgatacccc cgtcagactg attttttcta tgataccata
    33661 ttcggaagca tggaaccaga gaaaacggcg cttttctgct ggtaaattct acgcatttag
    33721 aacagcactt cggcggggat aggataaaac acccacatac cccgctgacc atgccggaaa
    33781 agccttgaaa tataagggct tttacagctc taagtgcgta ggtttccagt atcttttccg
    33841 ctggcgctcg gcctctttgc ggcggcgcat ccgtttggag caggccgcgc agtatttggc
    33901 ccggttagac ttcggcgtga acgtggcccc gcactcacag cagcgtttca cttcgtcccg
    33961 gtctttggtg atctcggcat acagggccgc atccagcggg aggacagcgg ccttaaacca
    34021 gcggcacaga agcgaatagg aaatgctctg tacgcaaata cattcttcgc cgtcgtccag
    34081 caacaggcag ttgccgtcac aatagttgca gcactcatgc gtcagcttcc gggccttgcg
    34141 atattgaggg taattcattc gtggaatact catagctctt gcgtccattc ctttcccggc
    34201 gtcatacgca aaatgccgtc cacattctgc ttgatgatgc cgtattcctg catctgcttt
    34261 ttcgcttcgc cgtacttctc atacagccgt tccttttcct cggccaatcg cttgtactcg
    34321 gctttcaggg cgtacagatc ggggagcttt ttcacaccct gtccctttag ggcctttgcc
    34381 gcagcttcat acaaaatcaa cgtgctttca tgctcacgcc ggaattttgc cttatccgct
    34441 gcattgcggt attccatagc cacgggccag agctgcttgt aggtagaaat attctttatc
    34501 agcaccgcca tatccgcaag ccggtgttcc atagctttga gggtagcggc ggcctcgtcg
    34561 ctggcggcgg tgatctcggc cactttgctt tccaaatccg ggtaggtgtc tatcccatgt
    34621 tcagtcagga aattcaaagt ctttgcggcc tgcttcaaat tgtggagctt cgcccacctc
    34681 tcatagcctg ccgactgctg ggccttaatg ttgttttcca gatcaatccg caaagaaatc
    34741 cccttgcgct ctttgggcgc tctggtgata acgcggcctt tgatacgctc tttgatggct
    34801 tcctcggtgt aggcttcccc caatgtcttg cagcgggtaa agcgttcctg tccgggagcg
    34861 cggaaagaaa taaactttcc cggcttgatc tcatagccct gcgcctgcat gagccgcagg
    34921 aaatcatcaa aatcttttgc ctgcgggata gcggcgtcaa tggctgcttt gagcttcgct
    34981 ttccagctcg tccctttccg ctgggcgtcc cactcggcat agctcttgcc cttactctgg
    35041 ccgggcttca ccacggacaa tccgttttcc ttgcacagcc tgtcgctggt gcgccggata
    35101 taggcatagc tctgtttgtt ggaaatgtac ttgcgctgat ttaccatatc cacggcacag
    35161 aaaataatgt gattgtggac gtggccctta tcaatatggg tagtcagcac atagggatat
    35221 ttcccttgca gcacttcctc ggcaagctgc ttcccgatct catgggcctg ttccggcgtg
    35281 gcttcgccgg gggcaaagga ttgtatcagg tggtggccca gattattgcc cttttggtat
    35341 gcctgcgcca gcagcatttc aaattcaatg tccgctgttt cataagagca ggcaaaggag
    35401 gccaccagca gcttgccgtc agttttgtcc gggttctcga tgtagtcaag ggcttttttc
    35461 agcgttgact tgataggatg tatctttgta actgccatat ctgcgccagc gcccccttta
    35521 tatcctcgat gtcctgtgcg tacaccggcc ccataccgtt cagcctcttt gcaatctgat
    35581 tgacgttgac gccgatcttc tgtatctcgg cggtctgcgc ccggatgtcg ctggtgtcca
    35641 tgttgacgat atagccgtca atgagcatct tccgggcgta ggctgaaaag ttcttcgtat
    35701 gcagcagcgc cattttctgt tcaatcatag cccgttcctc cggcgtcaca gggacgcgca
    35761 gcacgatttt tcgctttctg tttgccatgc ttcaccgtcc tttccattca ggggtttggg
    35821 gatttcccca acaagcaaaa cggacgcggc ccggcaggga cggggcaggc cgtttttccg
    35881 ggagtggcta cactccctat gcttgctacg ttactgtttc tccactaaca agacgtttcc
    35941 aaagccccaa actacccgca aaatagccct ctggaaagaa aaaagtgcaa aaaaatagaa
    36001 gctacgctgt gcagctcccg ctaaaagtaa aacagaggat gccagttaca catcctccgt
    36061 ttcattcttc ttcggctttt caattagtat ggcgctgtca atcgcgccct cgatgatcgg
    36121 caggtattct tcggggcaga gtttcagctt gtggctgacc ctttgccgca gttcgctttc
    36181 ctcccgcatg atctccgggt taaagtagcg ttccacagga agcccgcagg ctttaataag
    36241 ctgtatgaca accggcagac tgggaatggc cccgtcgttt tcgatgttgg caagatagcg
    36301 ccagtcaata tttattttct ctgccattgc tttgcgcgaa acgcgctttg cttgccgggc
    36361 cgctttcaca tccgcgccga aagtttcaaa gccgggacaa tcttcaatat tcgccatatc
    36421 gcacctccca cttacattgt atatttcata ctctgcccgt ggaatgttgg tatatgcacc
    36481 tttcttaaag tttatatttc acattttgtt tcttttattc ttcgagcaaa agaattataa
    36541 tgtaccctgt ggaggtgtac tatggactac atgacgttga aagaggcagg cgagaaatgg
    36601 ggtgtgcccc cacgatggat aaactactat tgtgctgcgg gacgcatccc cggcgctgta
    36661 aagatggcga cgatctggct cattcccaaa actgcggaaa agccgattga caggcgtaca
    36721 aagaaaggaa aggcggttac tgaatagtat aatgaaaccg gcgcattttg gatatggttt
    36781 tgaagagaga gaaagcatgg tattttgtca cggaaaaact ataagatgat agatggcagg
    36841 ctgctccaga ccgataaaaa gtattctcat ctgaaacaga aagaaaagat ttacacatgg
    36901 atgtatgaag aagcgaaact ttatcatgac agaaatggaa aatgcccgaa acaaagacga
    36961 ggaagctgct gctgtatcag ccgtatatgg tagaattgaa aaggccggca tctggattct
    37021 ttatggtgaa gtctccagac attggataac tgctggtcta atgcgccttt gagtatgggg
    37081 tgattgattt taataccggg gaggtacggc tttttgagga aaatattctg ggatttacat
    37141 ttggcgatta ttacatttcc tgtaactgca aggacacgga tgatgaagat atgaggaata
    37201 tagacttgct gattttctac tgtcttgaac ggtattagga ctgaatctgc tgcgcggagt
    37261 gcggcaagag cgaccggagg gagtacacac aggccctgcc tgtgtgaaaa gccataccgc
    37321 aaggtgcatt cgcaaaaaag aggccgcgca ttttgctgag gcttggggtg tccccaacaa
    37381 gcaaaacgag aacgccgcag gcgggcaagt ggtggatcag aatatccgta aaggatattc
    37441 tgatccattg cttgccagta ttatcgggat gttttgacaa ccgctgtaat cgaaacatcc
    37501 caaacattaa gaaggtgtta attattatta tcttgattta attcgtttaa accaataata
    37561 tagatacata caccatgaaa agaagcgagt atcccaatga cggatgatta aaatccgaaa
    37621 agaaatcgct ttgaaactac agggaaacta cagactgtta tgttatcttc ttaaaatgga
    37681 gggattttta tgtcgatacg aattctactt gtcgaggatg atgatcatat ctgtaataca
    37741 gtaagggcgt ttctggctga ggcaggatat caggtggatg cctgcacaga tggaaatgag
    37801 gcatacacca agttttacga aaacacttat caactggtta ttcttgatat tatgctgccc
    37861 ggtatgaacg ggcatgaact tttgcgtgaa tttcgtgcga aaaatgatac tcccattctg
    37921 atgatgacag ccctgtcgga tgacgaaaac caaatccggg cgtttgatct agaggcagac
    37981 gactatgtaa caaagccatt caagatgcag attttactaa agcgggtgga agccctgctg
    38041 cggcgcagcg gtgcgctggc aaaggaaatc cgtgtcggca ggctgacact tctgccggag
    38101 gatttcacgg tactttgtga cggtacagag ctgcccctga cacgaaaaga atttgaaatc
    38161 cttttgctgc tggtgcagaa caaaggcaga accttaacgc atgaaatcat tttgtcacgt
    38221 atatggggat atgactttga gagtgatggc agcacagtcc acactcatat caaaaatttg
    38281 cgggccaagc tgccggaaaa tatcatcaaa accattcgcg gtgtaggata ccgattggag
    38341 gaatcataat aatggaaaga aaagggattt tcattaaggt tttttcctat acgatcattg
    38401 tcctgctact gcttgtcggt gtaacagcaa cactgtttgc acagcaattt gtgtcttatt
    38461 tcagagtgat ggaattacag caaacagtaa aatcctatca gccattggtg gaactgattc
    38521 agaatagcga taggcttgat attcaagagg tggcagggct gtttcactac aataaccaat
    38581 cctttgagtt ttatattgaa gataaagagg gaagcgtact ctatgccaca ccaaatgcca
    38641 atacatcaaa tagttttaga cccgactttc tttatgtggt acatagagat gataatattt
    38701 cgattgttgc tcaaagcaag gcaggtgtgg gattgcttta tcaagggctg acaattcggg
    38761 gaattgttat gattgcgata atggttgtat tcagcctttt atgcgcgtat atctttgcgc
    38821 ggcaaatgac aacgccgatc aaagccttag cggacagtgc gaataaaatg gcaaacctga
    38881 aagatgtacc gccgccgctg gagcgaaagg atgagcttgg cgcactggct catgatatgc
    38941 attccatgta tgtcaggctg aaagaaacca tcgcaaggct ggaggatgaa atcgcaaggg
    39001 aacatgagtt ggaggaaaca cagcgatatt tctttgcggc agcttctcat gagctaaaaa
    39061 cgcccatcgc ggctacaagc gttctgttgg agggaatgct tgaaaatatc ggtgactaca
    39121 aagatcattc taagtatctg cgcgaatgca tcaaaatgat ggataggcag ggcaaaatca
    39181 tttccgaaat actggagctt gtcagcctga atgatgggag aatcgtaccc atagctgaac
    39241 cgttggacat agggcgcacg gttgccgagt tgctgcccga ttttcaaacc ttggcagagg
    39301 caaacaacca gcggttcgtc acagatattc cagccgggca aattgtcctg tccgatccga
    39361 ggctgctcca aaaggcacta tccaatgtca tattgaatgc agttcagaac acgccgcagg
    39421 gaggcgaggt acggatatgg agtgagcctg gtgctgaaaa atgccgcctt tttgttttga
    39481 acatgggcgt tcacattgat gatactgcgc ttccaaggct gttcacccca ttctatcgca
    39541 ttgatcaggc gcgaagcaga aaaagtgggc gaaacggttt aggacttgcc atcgtacaaa
    39601 aaacgctgga tgccatgagc ctccagtatg cgctggaaaa cacctcggat ggcgttttgt
    39661 tctggctgga tttaccgctc acatcaacat tgtaaatatt taaaacttaa atgattttga
    39721 ccgacaggta taaccctgcc ggtctttttt tgctgctaca ggaaaactac agactggcta
    39781 cagggaaagt acagatgcgc ttgccataat aacaatcgta ccagccacaa atcgtagttt
    39841 tattgcaaag gaggcattcg atcaaatgga aaaaagcaac tatcattcca atgcggatca
    39901 tcacaaacgg catatgaaac aatccgtgga aaagcgggct tttctatgtg cgttcattat
    39961 ttcgttcaca gtctgcacgc tgtttttggg gcggagactg gcttccgtat tggaggcaac
    40021 acagataccg cccatccctg caactcatac aggcagcagc actgacgtag tggagaattt
    40081 ggaggaaaac gctcttgcca ccgccaaaga acagggagat gaacaggaat ggagcctgat
    40141 tttagtgaac aggcagaacc ccatccccgc acagtacgat gtggagcttg agcaactatc
    40201 aaatggtgag cggatagata ttcggatttc tccctatctt caagatttgt ttgatgccgc
    40261 aagaactgat ggagtttacc cgattgtcgc atccggatac cgaacaacag aaaaacagca
    40321 agaaattatg gatgaaaaaa ttgccgaata taaggcgaaa ggctacacct ctgcacaggc
    40381 taaagcggaa gcagaaactt gggtggccgt gccgggaacg agcgagcatc agcttggtct
    40441 tgctgtggat atcaatgcgg acggaattca ttcaacaggc aacgaggttt atagatggct
    40501 ggatgaaaac agctatcgtt ttggttttat tcgtcgctac ccaccagaca agacagagat
    40561 aaccggtgtg agcaacgagc cgtggcatta ccgatatgtt ggcatcgaag ctgccacaga
    40621 gatgtacaac caaggggttt gccttgagga atatttaaaa ccagaaaaat gagaaaagga
    40681 tgttatggac agaaaaagat tgacacagcg tttcccgttc ctgcttccaa tgagacgggc
    40741 gcagagaaaa atgtgctttt atgcgggaat gagatttgac ggctgtcgct atgcgcagac
    40801 gataggggaa aaatcgcttt cccatttgct ctttgaaacg gattgcgcat tatacaacca
    40861 caataccgga tttgacatga tataccagga aaacaaggtg ttcaacttaa agctggcagc
    40921 aaagacctta aacggcttat tgataagacc gggggaaacc ttttctttct ggtggctggt
    40981 acgccatgcg gacaaagata ccccctataa agacggcctt acggtgacca atggtaaact
    41041 caccaccatg tcgggcggcg gtatgtgcca gatgagcaat ttactatttt ggatgttcct
    41101 gcatacgcca ttgacaatta tccagcgcag aggtcacgaa gtaaaggagt ttccagagcc
    41161 aaacagtgac gagattaaag gggtggatgc aaccatttca gagggctgga ttgatttaaa
    41221 agtgcgaaac gataccgact gcacctacca aatatgagtg accttagatg atgagaaaat
    41281 catcggtcag gtgtccgccg acaaagagcc ccaagcatta tacaaaatta caaatggcag
    41341 tatccagtat gtccgtgaaa gtggcgggat ttatgaatat gcccaggtta aacggatgca
    41401 agttgcctta ggtaccgggg aaataataga ttgcaagctg ctttatacaa acaaatgcaa
    41461 aatctgttat cccctcccgg aaagtgtgga tatt
//
LOCUS       DACDLM010000020        39913 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.020, whole genome shotgun sequence.
ACCESSION   DACDLM010000020 DACDLM010000000
VERSION     DACDLM010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39913)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39913)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39913
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.020"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(35..370)
                     /locus_tag="IV356_001079"
                     /pseudo
     CDS             complement(35..370)
                     /locus_tag="IV356_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(467..919)
                     /locus_tag="IV356_001080"
     CDS             complement(467..919)
                     /locus_tag="IV356_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014783.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            complement(926..1474)
                     /locus_tag="IV356_001081"
     CDS             complement(926..1474)
                     /locus_tag="IV356_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAP9014784.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            complement(1519..1851)
                     /locus_tag="IV356_001082"
     CDS             complement(1519..1851)
                     /locus_tag="IV356_001082"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014785.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(1865..2095)
                     /locus_tag="IV356_001083"
     CDS             complement(1865..2095)
                     /locus_tag="IV356_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014786.1"
                     /translation="MCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQKGYPYGPTN
                     LKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(2317..2859)
                     /locus_tag="IV356_001084"
     CDS             complement(2317..2859)
                     /locus_tag="IV356_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014787.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VDQEAQKIDAIKIYYVRSAY"
     gene            complement(2880..3971)
                     /locus_tag="IV356_001085"
     CDS             complement(2880..3971)
                     /locus_tag="IV356_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAP9014788.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(3979..6189)
                     /locus_tag="IV356_001086"
     CDS             complement(3979..6189)
                     /locus_tag="IV356_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014789.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(6205..8733)
                     /locus_tag="IV356_001087"
     CDS             complement(6205..8733)
                     /locus_tag="IV356_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAP9014790.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            complement(8785..9195)
                     /locus_tag="IV356_001088"
     CDS             complement(8785..9195)
                     /locus_tag="IV356_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014791.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            complement(9208..9426)
                     /locus_tag="IV356_001089"
     CDS             complement(9208..9426)
                     /locus_tag="IV356_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014792.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            complement(9423..10415)
                     /locus_tag="IV356_001090"
     CDS             complement(9423..10415)
                     /locus_tag="IV356_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP9014793.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            complement(10494..11405)
                     /locus_tag="IV356_001091"
     CDS             complement(10494..11405)
                     /locus_tag="IV356_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP9014794.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            complement(11424..11768)
                     /locus_tag="IV356_001092"
     CDS             complement(11424..11768)
                     /locus_tag="IV356_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014795.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            complement(11788..12344)
                     /locus_tag="IV356_001093"
                     /pseudo
     CDS             complement(11788..12344)
                     /locus_tag="IV356_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(12425..12925)
                     /locus_tag="IV356_001094"
     CDS             complement(12425..12925)
                     /locus_tag="IV356_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014796.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            complement(12926..13471)
                     /locus_tag="IV356_001095"
     CDS             complement(12926..13471)
                     /locus_tag="IV356_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014797.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            complement(13468..14724)
                     /locus_tag="IV356_001096"
     CDS             complement(13468..14724)
                     /locus_tag="IV356_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAP9014798.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            complement(15085..15396)
                     /locus_tag="IV356_001097"
     CDS             complement(15085..15396)
                     /locus_tag="IV356_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014799.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            complement(15419..16729)
                     /locus_tag="IV356_001098"
     CDS             complement(15419..16729)
                     /locus_tag="IV356_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HAP9014800.1"
                     /translation="MYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLV
                     RMLIDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGH
                     LLSEVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLIKTLDWVYDQSPN
                     MLIAGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEE
                     MIICLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDME
                     ARNRVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYL
                     MTFGEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYD
                     FTVKEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            complement(17343..17795)
                     /locus_tag="IV356_001099"
     CDS             complement(17343..17795)
                     /locus_tag="IV356_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014801.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            complement(17797..18162)
                     /locus_tag="IV356_001100"
     CDS             complement(17797..18162)
                     /locus_tag="IV356_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014802.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            complement(18261..21062)
                     /locus_tag="IV356_001101"
     CDS             complement(18261..21062)
                     /locus_tag="IV356_001101"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HAP9014803.1"
                     /translation="MYQADGKKIKEITLKKINGKVQAEIKDLDPGKYVLKEIKAPKGY
                     VLSDEAIEIVVEPGKTVNATAKDQVIKGTIDLVKVANKDLVDSTNPDNKPKLAGIEIT
                     LTSKTTGKVVKTVVTDNDGYATFGKNTVVFDTYILSETKGKEGYKLFEPLEVTISENG
                     QTFHYVLEDKVIEQRLKVVKVDQETGKVIPLANTEFKIFDTLANRYVTMEIPNDTETT
                     DIFKTNEKGFFLTNGTLTYGKDRYRLEEIKAPVNYVLNQNPLVFSITNDTEPIKVIHF
                     ANRQARKSVKLFKYEEWNKKKTPLAGVNFTLYNGKNQAIGEYTTDQNGEILVKGLVAD
                     DYYFLENAPLESFQPNTDKQAFTVAFKQNAPDDGETLVVSVRNYLIPPKLETQASNKA
                     DGEKVVDPLETIVIKDSVSYTNLFVGKEYTISGVLMNKATNAPILQDGKEITSTLAFI
                     ADKVNGTKDLEFVVNASVLKGQTIVVFEKLFRDGIEVAAHADINDEAQSVKVNNPTVH
                     TTAVFEDGLTVADPTGLFTLNDTVEITEILPGKAYLVKGILMDKATGEPLLVHGNTVE
                     TSVGFIAKAENETVIVPFTFDLTGINGREIVVFESLFRNDEELANHKDINDKGQTVRV
                     TNPSVRTTATHKPTGLKEVNPLTKVTITDAVKYHDLVVGKTYTVNGVLMDKVTEKPVL
                     VDGKEVTSTLTFVAETTDGTVNLDFILDARALRGKEVVVFEDLFREGVLLASHADITD
                     NDQTIKISNPTITTKATNKNGGKEILALPNQTVLEWVKVDGLAIGQIYRLIVQGYLTP
                     DGTPFEGTHAEKVFAADKEMMEFLFEFLVDGRNLAGKGLSFAEWLQAKTEDEKETFEE
                     VAKHNVDLTNKDQTVQIVEAPKPPQPVKPEQRVKPATVVPMLPKTGEQTSSILMVLGL
                     VVLVIALGITLYKVRKAKD"
     gene            21126..21650
                     /locus_tag="IV356_001102"
     CDS             21126..21650
                     /locus_tag="IV356_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014804.1"
                     /translation="MIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISII
                     SFWDKILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFW
                     EFLCDQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDE
                     RYFESYKLEKVKNT"
     gene            complement(21801..24410)
                     /gene="clpB"
                     /locus_tag="IV356_001103"
     CDS             complement(21801..24410)
                     /gene="clpB"
                     /locus_tag="IV356_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HAP9014805.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQPNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(24661..25707)
                     /locus_tag="IV356_001104"
     CDS             complement(24661..25707)
                     /locus_tag="IV356_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HAP9014806.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            complement(25718..25990)
                     /locus_tag="IV356_001105"
     CDS             complement(25718..25990)
                     /locus_tag="IV356_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HAP9014807.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            complement(26025..26933)
                     /locus_tag="IV356_001106"
     CDS             complement(26025..26933)
                     /locus_tag="IV356_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HAP9014808.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            complement(27065..28297)
                     /gene="pepT"
                     /locus_tag="IV356_001107"
     CDS             complement(27065..28297)
                     /gene="pepT"
                     /locus_tag="IV356_001107"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HAP9014809.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYILNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPPPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            complement(28312..29433)
                     /locus_tag="IV356_001108"
     CDS             complement(28312..29433)
                     /locus_tag="IV356_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HAP9014810.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            complement(29430..30131)
                     /locus_tag="IV356_001109"
     CDS             complement(29430..30131)
                     /locus_tag="IV356_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HAP9014811.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            complement(30275..30715)
                     /locus_tag="IV356_001110"
     CDS             complement(30275..30715)
                     /locus_tag="IV356_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAP9014812.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            complement(30844..31770)
                     /gene="dnaI"
                     /locus_tag="IV356_001111"
     CDS             complement(30844..31770)
                     /gene="dnaI"
                     /locus_tag="IV356_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HAP9014813.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            complement(31770..33143)
                     /locus_tag="IV356_001112"
     CDS             complement(31770..33143)
                     /locus_tag="IV356_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Replication initiation and membrane attachment"
                     /protein_id="HAP9014814.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            complement(33166..33657)
                     /gene="nrdR"
                     /locus_tag="IV356_001113"
     CDS             complement(33166..33657)
                     /gene="nrdR"
                     /locus_tag="IV356_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HAP9014815.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            complement(33969..34301)
                     /locus_tag="IV356_001114"
     CDS             complement(33969..34301)
                     /locus_tag="IV356_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAP9014816.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            complement(34353..34982)
                     /locus_tag="IV356_001115"
     CDS             complement(34353..34982)
                     /locus_tag="IV356_001115"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HAP9014817.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            complement(34946..35782)
                     /gene="mutM"
                     /locus_tag="IV356_001116"
     CDS             complement(34946..35782)
                     /gene="mutM"
                     /locus_tag="IV356_001116"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HAP9014818.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            complement(35827..38472)
                     /gene="polA"
                     /locus_tag="IV356_001117"
     CDS             complement(35827..38472)
                     /gene="polA"
                     /locus_tag="IV356_001117"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HAP9014819.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            complement(38598..39281)
                     /locus_tag="IV356_001118"
     CDS             complement(38598..39281)
                     /locus_tag="IV356_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HAP9014820.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            complement(39274..39759)
                     /locus_tag="IV356_001119"
     CDS             complement(39274..39759)
                     /locus_tag="IV356_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HAP9014821.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
BASE COUNT        11346 a         8603 c         6361 g        13603 t
ORIGIN      
        1 cgtatagttt tagtattctt attttttatc accagtaacc aattgagaac agccctaaag
       61 cagaatagtc ttttatctca aaacgcttaa tttcaggctt aggaatatga ataatctttt
      121 gagtatattc tttctctttt aatcttactg aagaaatacc actgcctatc ttttttacaa
      181 atatttcatt tggtgtacag actaataaaa caatatttgt aatcaatcct tgcactaaag
      241 aattaaaagg aagactattt aaaacagggt gtgcataact ataacatgtg aagtagttat
      301 tttgaacttt aacttttaaa aactttaaaa ataatcttat ttgttcttct aaacaatcat
      361 ctatactcat ataatcactc cactaattaa tctccccaaa aagacacagc attaagagat
      421 ataccaacac aacagtgcaa ataactctac atcttccttc gcaaccttat ttcaataaac
      481 cataaaaatt attttttaat agaaactgaa aattaaaact agaaaaagta gttttaccga
      541 atgtaagagc atcatcacca tcaatataga aatacattct tttccagtta catttaattt
      601 ttaaacaaaa ttctccccaa aaaggaactt tttctagtga aaacttggta atctctttgt
      661 aattaattct tgttaaagaa taattaaaca cttcattttt acttgttatt ttttcattga
      721 ctataactag ttcatctggt aaaaaaatta accaacaaac atcgacaaac agtaaatgat
      781 ataatccatt tccacctcca agcatattca atactggtga acatgcctta gaaacacgaa
      841 tatagttatg gtttaaatag atattttctt taaacattgc ttgtttaaaa gccatatgct
      901 cttgttctaa acttttcata aacttttact ctaatgcaca gctagcagca gctgctgcaa
      961 ttcctgctac aatatttacc ttagctaact ctttagctgc agcttttcct aattgttttt
     1021 ctgcaatttt taataataaa tccgcagctt tttcaaaatt aaaagctttt aatgcttcaa
     1081 taaaatctcc ctgcgtacct atagcccaag ccactcctcc tccaggaaga gaattaatgg
     1141 ctacacatcc agcatatcgt ttccaatcaa ctttctccat tctaggaaca ataatatgtt
     1201 cataaaagac tcttgctgct cttccttgtt cgttatcttg actgattcgt tcacgaatag
     1261 caccaaaatc ctttatatgg tatacaccat gttcgtctaa aaaaccaact gtatcaaaat
     1321 aaaaagttaa ttcatctact aatttattct ttatttctaa atcaactgta ttcacttttt
     1381 ctgtggcata cacacttgtt ccagtactaa caaaagtact taaacctaat aagaaaacac
     1441 ctaaaacacc aaatatttta attattcttt tcataatttc tcctccataa aaaataagtt
     1501 actttttaaa tatcttgttt atgaattcat tccccaaagg ccttttaaga ttgatacagc
     1561 agtccgttca cttcttttag acttgtcata caagtctttt aaatgatccc atatcagact
     1621 agtttgtcta tctagcttca atccattaaa cgctaatgaa cggttcattt tttctattac
     1681 tttagataaa gctacagaaa tttttatacc ttcacaacgc gcatcttgga tttcaataat
     1741 agtatcatca attagttttt gaatttcttg cctatcaaca tattcaatct tagaaagaga
     1801 atcttttaaa gctactaatg attcaacgat ttcttttttc tcttcagaca ttttcttcct
     1861 ccttctagtg acccgtaaag ccatgtagag cagagtccat tgaaccagta attacactat
     1921 ctacaacgcc attccaattt actctacatt ttccattttt cagatttgtc ggtccatacg
     1981 gatagccttt ttgacattca atgttcggat tataccagat aggattatac cattcagccg
     2041 cagaagcaga ttcagtcgat acaaacaatc ccacaccaac aaatccaata cacatcacac
     2101 tatagccaat tagttttttc atctcgtatc catctcctaa aaaatagaat agttcttata
     2161 gttattcata agacatattt tttccgtttt tgttttatcc tttctgtcct ataacaactt
     2221 ttttcaagta aagaatgaca tagtttttct taaaaaaaca gtctgttttt ttctatttct
     2281 tcggtgtata ataaatatga gtgttcattt tttattttaa tacgcactcc gtacataata
     2341 aatcttgatc gcatcaatct tttgagcttc ttgatctact ttcaattgaa gtaatacaaa
     2401 ttgagtaacc ttattcattg tttcttctcc aaataacaaa tattgatccg gattctctat
     2461 atcttgtgtc acctggtaaa gtttcccagt tgttttcatt tgtacatgcg ggtctacatc
     2521 aatactattg tctttaatac aacgatctgt catatagtcc ctcacagctt gattgcgttt
     2581 ataaacatct gtgaaattac tccattttct agcaaaatct tttaagaaat tttttgtcat
     2641 ttcatctatt tgcatttgtt gcgctgtctc gtcttctaat gaaccaattt gactgttact
     2701 ttcagtactt tgaagagttc cacttgtttc ttttactgct tcgattgttt cttctgtcgt
     2761 tctcaattgt gttttttgtt tttcagaaga aaaccaatga caaccagtaa gacctatcaa
     2821 acataaccaa ctaaatacta aaattatccc ttttttcacg tttctagtca ctgcctttct
     2881 tatttcacct tacgaaccag actacgaatt tttgtttgat tgtacgtgcg ttgataccga
     2941 gccataatcc gtccttgctc ggcattctgt tccacactag agaaatgttg tccgccatat
     3001 gaaacatctg ttataattcc ggtgtgacca tagattccag gagacaatgc accacctgct
     3061 tgccaattca ccacatctcc tgcttgtaaa tcacttggtt ttgggttcat gattacttgc
     3121 caaccatagg ttgtccagtt ataatcttcc cctattaaca tcgcaaacat gtgtccagaa
     3181 cccattaact gtgggccacc taattgagat acataccatg ccgtaccacc ataacattcc
     3241 ccattattta cggatcgtcc aatgatccga tccaaaacct tcgcattgcc tttacttttt
     3301 cctgcaataa gcgaagtttt ttttgttggt aggctattcc aatgcttgat cgcaaaagta
     3361 tcatattccg ttaagttata ggacgttatg atactcattg ctcctcgata atacggactc
     3421 ccttcggtaa tacctgctgc cgcatagcct ccacgaccta gaatcaataa acaacttcca
     3481 ggatctttat tgcccacaca ttgattaaag ttgctttggc tcgccaccat aaagccataa
     3541 tagtcataac aagcttttaa gttcggaaac ttcatataga aaccaccttc agaaccacca
     3601 attccacgtg cagaaccttg tgggtaggga caaccaggaa accaggtaat cccaaaaaag
     3661 ttcgtatcgt ttcttccaga ttgtgactgt ccataagctg attcatagcc taattgagaa
     3721 agaatcacac tcggtaataa ctgatacttt acagctgcac caactgctgc ttgcgcatgt
     3781 tcatctgtga ttggaccacg tcctttaatc tctgaaaaaa tcggtaatcc ttcggtatat
     3841 tccccattaa aagcgacagc tagacctgta gcttctcctc catgctcaga aagttctcct
     3901 gaaaaaaaga atggcaatag aaaaaaggga agaataaaga aaagaagaca acctagacac
     3961 cctttcttca tttcttcctc atcctttctt cgataatggt ttttggactg ttcgtccttt
     4021 tggtaaagta aaatcagttc ctggttttgc gtccaaaatc ggcagtgttt taggatcctt
     4081 ttctattttt tccgattgct ctgttggctt atctaaagaa gaaaatgcag gttgtaacga
     4141 ttttggtgcg gaaatcgacg gtttactttc agacgaacgt tgccccggtt gttgcacaga
     4201 acgatttcct gatagagtgg ctaccgacga attaggaaca gagtattggt tcaataactg
     4261 ctgcattgct ggataactcc catttttcgc ctgatttttc acttggcgaa tctgttgtga
     4321 aagagaacca gcagctgtta attgtggcac gggtactttt ccagaaggca acggaatcga
     4381 ttgaccaaca aaagcgatac ctttatttaa caatggtttt ctttgattat tcccttgttg
     4441 cttactcaat tgtgccaatg attgtacctg ttgttttggt cttactgaat tcatggacga
     4501 atttggaatc aaaccatttg aaagaccaga attccactct gttttcgatt tggtagaaga
     4561 catttcaggc tctaccccat gataacgaac atgacgacca ctataaggca aggcttgatt
     4621 tgaacgccca cctagttcaa agggattaac cacttgcctc ccttttaccg attcttgtgg
     4681 tgtacgtttt tgttgaaact tttgaaatcc atgtatcgct gcagaagcga gtggattcgt
     4741 tgctcgatac acattccctg ctaatcctgc acctttgatt gccaaatttt gtccagcagt
     4801 tgatagttga ccaggcagtt gtttcatttg agacaaagaa tgacttgcta tgtttttcgt
     4861 gttgtttata gtttgatctg cagctcctaa ccctagtttc tttaataaat ctttccgttt
     4921 tacaatgagt aaaattgata ggagtgcttt gacaaacata tttcctaaaa aaccaaaaac
     4981 agtattcatt ggaattaaat cgtctactat gttatagatc aaaaatgcca ccaaaataat
     5041 cacactgtaa aaagattttt gaaacatcaa gcccaaaaag gactttaagg tattcatgag
     5101 catataatca aatactggaa caaaagaagc gagtaatgaa aaaggaatca caagtaataa
     5161 acacaacacc aacatttgaa agataaaacg aatcatgcca atcactacaa gtggtaatcc
     5221 aatacttaga ttaagcaatg gcaccataga accaacgact gctttataaa cagctttagt
     5281 tggttgaata tagacacgat aagccttctt tttccctcta tcttctcctg cagcagtggt
     5341 cacttttgtc tcaatatcag ataattcttc acttgacgct tccttggcta gaaattcttg
     5401 tggttcaatc tctgcttgat acaattcttc taaatttgtt gtcccataat ttaacaatat
     5461 atacggatca acaacagccg ctttataata aagttggcgc actttttgaa tggcttcctt
     5521 ttgtgtcgtt ggcactaaaa caccattgac atcttttgtc gccaattcat ctagactatt
     5581 tgtagcagaa aaaataaagc cttctacctc cacggacaaa tcatttaacc ctttggtaaa
     5641 agcttctcct ttactaggta cgttactacc atagccaaac caaaccattg aaaaaatgac
     5701 aacgaagaga aatcgaataa acaccatttt tgcgtaatgt ttccctctaa atatacgaag
     5761 agtaaataga tataacacat acaagacgac aatccccgca ccaataggat cgtatatttt
     5821 tgaataaata gtatccgaaa aagtgaaaaa ctggtgaatt aactcgttca ttgcagctcc
     5881 ttcatagagc ttctcaatga caaaatcaag gccttgccaa atcaatttac ttaaactaaa
     5941 gaacatattc gtcatcattt ttagaaaatc tgtgccattt gccccaaata acattttgcc
     6001 taatgaaaat tcactatcag ataaataaga agaaaaggta tcaatatgaa atttcccaat
     6061 ctcatagatc gattgatcca cctgcttttc tgccgcatac accaatccac caacaaaaag
     6121 cagtccgaat ccaatcgtta aaaaaaacaa aacgcaccat ttcttttcct tatgctttat
     6181 ataagccatt gtttcacctc atttctattg catgattaac gtatcctgtt cttctacttg
     6241 agagtgactt gttttttccg ttgtttgtaa tgcagcggtc atttcttcaa acaaactgtg
     6301 tacattgagt tttcctacac gtccataggg atctaacatc caacactgtc ctttaatcat
     6361 gtggctcatt tcagctaagt tcgcttcatt tacttccaaa cgtaaatgat tcaaaatctt
     6421 ttctcgctca ctgtcttcat caaaagcaaa gacgacacca aaattccctt tttctttatc
     6481 tgaacctaag tcaccaataa attgtgtatc taacactaat tgattcatct gggaacgccc
     6541 cacacgtgcc attgctgcaa taatactacg tcctgcgttc gaattattaa atacccatgc
     6601 ttctgtaaaa taaatcgctg ttttcttact actatctcgt tttccaaaca tttcacaaaa
     6661 acgacctaaa ctaatcatca aacacaaaga ctttcgatcc gcatctgtat atagttctgg
     6721 tcggacattg tcatttggta atttcaaatc ttggatctct aaaatcgttg ttttggcatt
     6781 aaagtctaat cccgggtttt ctccataaga aaatcctaaa cgtaaaatcg aatcttctac
     6841 cgtcaagcgt aaaaactcac catattctcg aacctctttt tgttccattt gttctaaata
     6901 gtcgaccaca tgcatcaagc caacttgttg tccggcttct ttttgaacta aaacttcttg
     6961 gattcccttt aataccgccc cttttaaaag gtgattggta cctaacggac ttaactcatc
     7021 aatcatatcc tgggctactt gtttcgcatc tactcgggat aaacaaacaa ttggatctaa
     7081 tacaccataa ttacggggat ttgtagcatc taacgtgaca taactcattt tttgcaaatg
     7141 ttctacaaac aaagggtaat gtttctgata atacgggtct tgaatgagtt tcgtaaacca
     7201 tttgcgcttt tctcctttgg gatccacaaa taaactttgt acattcataa acgaactata
     7261 caaaaagagc aagccaacta aaaaggtctt ccctttaccg gtttttccag ttactgctac
     7321 atgaggcgca tcaaacaacg cacctttgat tccttccgca atggctagaa gattcaaaaa
     7381 gacaaaacga tttgacgcat aaattaattc ttctaatggt gttttttctc ctcgagaacc
     7441 accatcccct aatgtatctt gccgaccaat ataccagccg gattccatac ctaattctga
     7501 tactgctgaa aacaaccatt cgccaactgc ttctacagtt gttcggtgct tccaatgtaa
     7561 ctgccgtccc aatggttgcc ctaataaaca tttatagaac aattctcgtt gatcattttt
     7621 tgcacggtgg atatggataa tcgtatgaag ttgttgaata accgttgcac tattttgacg
     7681 aacttcttca accgtttgac cgtatacaat aaaacatgcg atccaatcga cgacaggttg
     7741 cccattatct actcgttgct ttaaatgttt tactaatcct cgaacagtta ataagcgttc
     7801 actaggttct tcatcatttt gaaccaattc cttatgctct gttttgaacc gttccgatag
     7861 ccaattcagt tttaaaccaa tacctccctg tcctttcaag cgtggatagt gaattttcat
     7921 tcgcaattct gctgggaaag aaagatcctg agcaaattga aatagatcac aatttctcat
     7981 attttcaggt gtttccccaa taggcaacaa tgctaaataa ctactcccta actcatcttc
     8041 taattgaaga aggcctttat gttccttcgg tatacgtaca tacgttcctt gattgtcttt
     8101 cagtacttcc caattatttt gttcttctac tttgtgagcc attcctcgaa tatattgcag
     8161 acgattgaga tacaacagct ctttttttac taagggacga atagaaaagc tataaagtaa
     8221 ttgtgtcact tcttttacat aaggatcact ttcagaaaac aaagtttcca aatcatctac
     8281 ttctaatcca aataagcgtg ctaaacttcc tgctaaatct aaccagatta gatttattac
     8341 atcatgaaaa ctctccaccg ttgctttttc tttgactttg attcctaaaa taaatgaagg
     8401 acgatagact tgaccttctc gttccaacaa tgtcactgtt tcttttgcat aatacgcacc
     8461 aattgcttga ctatcgggag aaaatccctt tcctaatgtg tcaaacttcg tccgtaaatt
     8521 cattgttcgt ggatacatca ccaactccac atcttcataa tctgctaaaa gcaacagtaa
     8581 acgagccatc atttctttta tttcctgtgt cttttttggt gtgttttttg aaattgttcg
     8641 tggaaaaaca tgatagtagg cccagataca atcctctcca tttaacaaac aatttttctt
     8701 gaatgctttt actggttctt ttacaagcac caatgaattt cacctcccaa taaaaaagga
     8761 acaaccagtt gattgtccct ttttctaatc ctctaaataa acatacttat tcacaaaaag
     8821 taattcttcc aatgcattgt ttgatacctt gtcccagtta taatacacac aatcaccatt
     8881 catcatacga atcatataac aaaaccaatc ccataaataa aaatgcactt tttttccatc
     8941 aggttttagt tttgccagtg ctaacacaca taaatagggg agtcctatat aaaaaacaac
     9001 tcctgctggt ggaaaaaaag aaatgaccca accaataaat gaacgtaaaa ataaatattc
     9061 aaagattacg accaacaaaa aagttgctgc attgactaat gcaactggaa atggaagacg
     9121 ccaattgctt gtaatctgtt gtacgcgata aggttccgca taaacaatcg aataatcata
     9181 aggttcccaa tccacttcac tatcctccta atccataaat aatttttcaa tgattttacc
     9241 aaacgcatca aatacacgtg ttggatcatt taagaagaaa taaactgcgg cacctgctgc
     9301 gatagatatt aatgcatttc ctacttttga tttcataaaa tttcgcaatc ccagataaac
     9361 aaccaccatt attaaaaaat agccaccttg cgttaatata aaatctacaa ttcccttcag
     9421 tgtcatttcc gttcttctcc tttcctatcc aaccaattat gtgttaattt ttcaacataa
     9481 tactgatttg tttttttcgt aatgacaatc gtcatttgtt ctttttgtaa aagtgacgta
     9541 tcaccatctc gaaagacgac cgttgctttt acaataaaag gttttttcgt ttctttataa
     9601 cgcaatactt tcatctctac ttgatcaact ttagctgttt gattgagtcc ttcaggttct
     9661 ttcatcatgt atgacatatc ttttgcattg tttttcgcat acttatctaa gaaatcttcc
     9721 acaaatcctt caacatcttt cgcttccgac gcatcaaccg tttcgtataa tgtgtcatca
     9781 taagtaatca ttcgttgttt ttctgtattc tttggtagtg ccgtaaaata aggataagca
     9841 ataatacgac agcccttgtt tgaaatagaa aagggaagat tgagtacttg tgtgattgtc
     9901 acacttgttt ctttcttact ctctggattc atcgagcgaa tatcataagt tactttataa
     9961 ctagcagttg gaatggtttc aatttctttt aatccaataa acgaagcagc agttaatttt
    10021 cgaacacctg aaacacttcc tggttcttga ataaagtttt gtgcataaaa ctcttttttt
    10081 aatgtttctt gacgttgttg ttcttgttca tgattatcga atgtattcat atacaaagca
    10141 acaaaacgat tcataaagga ttcaatttca ggtgtgtacg ttaattctga ccgactttgt
    10201 acttctttct tttgtaattg ttggatttca tctttcaaaa acgacacttg aaccttcgtt
    10261 ttcatggatt gaaaaaatgc caagccccct gaaaaacaaa gaaataaaac caaacaccaa
    10321 atccatttca ctgctttttt tgaatggatt ttcttttgct tcggtacttt ctctgtataa
    10381 actttttctt tccgccgtag ttgtcgtttt ttcataagct actccttcta gtatgttttt
    10441 actagtacgt acgattgaca acgataagct tgtttttctg aaaaatagtc cattcaatta
    10501 ccctcatttt ctattccttt tctctttctt ttatatccaa caaatccagc aatacttgtc
    10561 aacactcctc ctagaacaga aagtgcaaca tgtatttctt caccagtctt tggtaagact
    10621 tttgtttttc catctgctgt tttgatttca atattgccac ttggaagttt ctttacagga
    10681 atcgacaaat cctttaccaa attcccttca ctatcttgga ttaatggaat accatctttt
    10741 acaccaacaa ttgtttgatc acctgctact tttaatgggg tggttggtgt tggaatatgg
    10801 gtcaattcct ctacattact agtgacaatc ggtacactca ttccttgaga agtattcgtc
    10861 gtaatttcac cgcttggggt taccgatact gtgacttctt ttgctggaac aataggttta
    10921 ttttcttttg gaattgcttc tgatttttca acaggttgtt tcggttcttc tttttgttct
    10981 tcactggtag acgacatcgt tggctgttcc gtacttgacg aatcagtatt cttttcagaa
    11041 gaactggttg ttcctgattg ttccggagtt gtgactatac ttgaatccgt tgttgttgaa
    11101 ctatgcacac cttcttcttc gatcgaatca gtcggtaaag ttgattcagg aaactctggt
    11161 tctggtgtca ctggctcttt ttcaggtttc tctgactgca attgttcagg ttctgctggt
    11221 ttttccgttg ttcctccatt tagctctgtc tcaacatctg gtaatccttc ccctggcaat
    11281 gtttctacaa tttctgactt aggtgtttct acagtttcat ctgcataaac caatgaactc
    11341 cctaattgaa acgaaaataa tgaaattcct agtgttgtta cgactgctaa tgttgttttt
    11401 ttcatgatta ttcctccaat tttttatgca attcgtgttt tgttcataga cgccgcacta
    11461 atattatctg aacgataaaa gaactcccgt ccgttttctt ctaacccaac atatggatta
    11521 tttttgaata attgaatcaa tagttcactg gtgttgtatt ttggatagtt tgcaaaaaaa
    11581 taatactgtg cttgtcgccc atccgaaaat tcaacaagta attcataacg ataccgcttc
    11641 aatccttttc gttgttttaa aggatctcta taccaacttg tccatcgttc cattcgtgga
    11701 tagagataga cacgatacac atagaacaat gccataccac ataccaccaa aaataataat
    11761 cgccacataa aaattccccc ttttcttcta cctttcttga atcatcgaac attcataccc
    11821 tctatagaga tttgaaaaat ccatcatcaa ttgttcatat aaacgttgtt gcaaatagcg
    11881 attgtttcga atacataatt cttcatagcc atcaatcact tgatcttctt tttcatagca
    11941 tcttgtagct ctatgacgct cagcttgcat gacataacca aactctgcac catatcgttc
    12001 tactgttaat aactgttgac tacgcaataa tgcaatataa caatcacaaa aatgttcaac
    12061 cgacatttga tttttctcac gtttgtgaaa taggtattct ttagaaagca cattattcgt
    12121 taaacaatct gataaatagc gataatctgg cggtcggtta ttttcatctg tgaatttttc
    12181 ccataataaa ctgattttta ttcgttcagc ggctagatag tcttgttcgc gtggataaaa
    12241 ttcatcaatc gcacaaagtt ttttatcacc tgaataaaca aatccatata atgcgaaacg
    12301 aactcttcct tttcaattgg ctctcctaaa aattccagtg acataccatc ttctccttcc
    12361 taaaaaaaat aaaaaagcag aaaccgattt ggcttctact tttctttcct tttatagctc
    12421 ttttttacgg aagaatccgc aaatgacatt ttttcaaaaa atcaatcggc acaagttcac
    12481 gaaaacttgg agcaattttg gatagaatca cttccccatc ttgtaaaata caatcataaa
    12541 aatcatcagt tacttgatac ttacgcttct tacaataatt gataaaatag tagcgatcat
    12601 tttctatttc cattcgttgt tctactaagc gcatacgaac atcatcatag aaataagcca
    12661 caaatcgccc ttcaagttca tgtttttcaa tgggatactc ttctggtaac aatctatttt
    12721 ttcgtcgttt atacattgct ggatacctta gaagaagttc atctaaacgt ctgtcagtat
    12781 atggtaactg acgaatcaac gattctaatc gttctttata cagatagaat aattggcgca
    12841 agcaatagtg taccgcctct ggattttcta atactgttgg atcacgtgac caatacgcac
    12901 caacataaat cataattttt ttcatttaga caatcacacc agcaatacta atgaccgatc
    12961 cacaataggt agaacaagtg gcatagcgac caatttcctc taattctatc tcaatctctt
    13021 ctaaagaaag atatgtctgt tcttctgttg gctggcgact catttcccaa gtgacagtca
    13081 ccaatgaaat ttcttccata agaggttttt cgctgctaag tgctgccaca cagttttcat
    13141 atatcttcat tttatcgcag ccttttttaa ccgctaaaat cgcaggtatt ggcaatgaaa
    13201 atcgataaaa gcgaatgaat tctagccttc ctttccttcg gctaaattcc aactcttcga
    13261 gttcttgttc gtatccctta cgaacttcta ataagcgtgc aatttcttgc cagttctctt
    13321 tttcctgata acgtccagct tttaccgctt gttcaatata aggaactcga aaacgaaaat
    13381 aagacaaatc aaccatcttt tcatttaatg cttcgattgc agcctttaaa tccaacaggc
    13441 gcagccattc tgttgtcgta tatgcattca tgcaattttc cctcctgacg ttcccatcca
    13501 ttctagatag ttttgttgct cgtcatttag ttcggcatta tcaatccctt cttgtacaaa
    13561 gtctcttcct aaaatacgat ctgcttcttg taacaacttt aatgtcggag ctacttgttt
    13621 caaaaaccag cgttctgaac gatctaatga gaatttttct ggctttactg taaaatccaa
    13681 ttcttccatc gaacgaaata attttgccca tcgtttatca acaatccgtg catcactttc
    13741 cagtctatcc caaacaataa gttttgcatt aattaaacca acgccaatct ctcctaaacg
    13801 tttcggtgaa tcacctaaaa taaatgcttc tactgcttgt gttgctttct cattggctaa
    13861 ccgtaactca tatcgattat aaataccata tttcgttaat gcttctaatt ctgaaatttt
    13921 ttctcggttc gcaatttcaa aacgtttctc ataaaaatta aaaaagagag gactctttcg
    13981 cgatccaaaa tacaaagata atccttcact tcgaaaatag ccatcatcta aaaaacaacc
    14041 gccaatattc tggaatctct taaagtccat ttctaataaa cctgcttttt gtttttctag
    14101 taattcaaag agatcgaaat gttcttccgt ttccaatccc caaagttcat ctaacgcaat
    14161 atcgaatcgg ctacattgca cacgtgtata accagcttcc aactttcctt gatttttcca
    14221 aatggaatat agccatgttc gccaatctgt ttgttgttca cgcatgactt cctcatattc
    14281 ccggcaacct tgtcctgaaa attgcacaag tacattttct gttacagttc gttttgaatg
    14341 ccagaacacc cagatattcc cacgaacaga aagacagtca aaaagataca agcccgttgg
    14401 acgtgtttca aattctgtca gatccattcg taatacacgt tgaatcactg ttttgtagtc
    14461 tgtcccaaaa aaggaaagac gcaaataatc aatcattgct cgaagatcta ttccgctttt
    14521 catatacaat cgaaagcgtt ccttgattcg ttgttcaaaa tcctctggga tttttctttt
    14581 cccttgttcc atctttctaa tgtaatcttt tgagcagccc atcaattgcg caaatcttgc
    14641 ttgtgatagc ggctttttat ctccacttat attatgaatt gcacttaact tctttctgta
    14701 gctttttagc tcaatcggtg tcattttctc gctcctttta taaaataaca aaatcgattt
    14761 tttttaaccc tttagaaaca ccgatatatc aactagtccc cctcgttttt tgggaaaagt
    14821 agtacaactg ctgaccttag ataatcactt gatacaaaag ggtttataaa acttttttct
    14881 atgtgttatg ttatttctgc cccccatatt atatatcggg gggctttaca caaagaggcc
    14941 gtgcgcaagc gcacgacctc tttgtgagct gcacacgctg ctagcgagtg cgcattatag
    15001 gcccatgctt cgcagcctta atgcgcaccg ccaggcagag tgcggctacc agactacgtc
    15061 tagagccctc ccgatagata ataactacaa aattaaatga tctaattttg ttatttcact
    15121 atatttttca ggagaaaaaa cgcgataaat tgacaaagtt aaatcctctt ctaaatctac
    15181 tcgataatga tacaatcgag tcaatcgttc tatatctttt ttcgttagca atacttgatt
    15241 aataactttt cctgtaaaaa cacgttcttt gcgcaaaaag cggtaatcag ttacttgttc
    15301 aatacgattc aaccaatcat aaaacgttct ggaagaaaga gaaggattaa tcattcgtat
    15361 tgctgtagct actctataat aacaactctc tgccatttaa cttcacctcc ttagttgatt
    15421 acaaaatatg cgcatcagaa aaacttgttc cttttggatc ttttgctaaa tacatttggc
    15481 gctctagttg ttcttgtaac aactgattat catctcccat cgtttgatct tgactatcct
    15541 cttttactgt aaaatcatag acaatcattt cagtaaattt ctcaaattct ttgataaagt
    15601 gataatcttt gtaaacaaat ggcgcaaaaa actctacagg tacatcaaat cctggaaaag
    15661 catatccacg accaggttga tctttgttgt aaaatggctt atttttaaaa tcttctccaa
    15721 aagtcattaa ataaccaatg ggagacaatc gaccaacaga aatacggaat gttaaattat
    15781 cccgaacacc acttggaaaa tattctgcat ctggtcgttg cattgctaaa ataatgtaca
    15841 tccctgcttg acgacccttt aatactaatg gctgaatcaa tttatcgact ctatttctcg
    15901 cttccatatc caacgaacca taaaaagctg cccattcatc aaaaaagata aaatgcggtg
    15961 gtaacccata ataagcataa tttttccctg gttcatattt aggatctttc atggttttca
    16021 tataggcata ccgttgattc atttctttta atgcatttcg taaacaaata atcatttctt
    16081 catttatttt gtaaaacaca tgtcctttga atacatcgac gtcacctaat gctgctaaat
    16141 ctgccgcttt tccatcgcaa atatctactg tcccaacact taaacaagct tgaattaaag
    16201 aatacaataa ataggttttc ccaccaccga ttgcaccagc aatcaacata tttggtgatt
    16261 gatcatatac ccaatccaaa gtttttatta aatgaatacg tccattttct gctatacatt
    16321 gatcaatagg aatccgacca gaatctgaaa ggaatacata attgattcgg gctttttctc
    16381 gttcttcacg aattaaatca cgcaaaaata cttcagataa caaatgaccc atttttaaaa
    16441 atcgttcgtg aaaacgccca ccatctaaag gaaaagaaac cactaattct tgtttctttt
    16501 gataaaaata aacttttggt aatctcattt tttcccttgt ttgtttctca ctaacttgtt
    16561 tctttgtata aacaaaccga ttgtcaatta acattcgaac aagtaactga cgccaataaa
    16621 cagaggcaaa atatccttct tttagtcgcg accaatgcat caaccctaaa attaacccac
    16681 taaccagcaa caaatacaac acaatactta ttccaggaat aagatacatt tgccaattcg
    16741 aaaacgtact taaacgtgga taaaatactt tccaactaaa ccaacctaac agaatcaaaa
    16801 atggaaacaa aaagaaacca taatagcaaa accataaata acgattgaaa tagcgaattc
    16861 gccgaccacg atacttgaaa aaatgagctt tcaattgtca cattcctcct ttctgttttt
    16921 acttttcctg tgctaaaaac ttttgacaaa aagcaactaa tacaggaata tcacatttag
    16981 taaaaaaaca taatcgaaaa agatttaatc gatttttata agggtgtgca cacatattac
    17041 atattcgtac tatacgaatc caaatcactt cctgatgatc ttgtttccac tggtacggta
    17101 atgaaaaacg aacaagatca cgtaaaaaca tacactgccc aataaccgca caaatatatg
    17161 catttgtttg tacaaaaatc gttggattgt ctccaaaata ctcaatcaat tgttggatat
    17221 tttgataaca agcacaatct ctcaaagtat ttgattggtt ttatctgaat tcaaaatctc
    17281 cccttccttc tatcttagat aaaaagaata ggaagactcc ttcctattct ttcaaaaaaa
    17341 ccttattttt tctctttttc cttagaatca acacttggtt gtttttgatc taaacctttt
    17401 tcttgtgatt gtttcatatt aggattattt gttggagctt ctactttctc taatcctttc
    17461 gcataaatca ctaaatctga atattcacga ttgccatctt gtgctggaat atataccaca
    17521 tgatattctg gatcaattaa tttcacagga tcacgtcgtt taaaaccagt caaatctaca
    17581 tctgctggaa atttaactcg tcgtgcaatc tttggttcat ctggatttcc aaaaactaat
    17641 tgtgctcgct gtgatcgaat ttctcccgta taatcgcctg tttcattatc aaatacacga
    17701 tcagactctt ctaatgcgcc aaagcgtacg gctcctaaac aagtttcatc taatgcttct
    17761 gtaatgtcat aattatttgg aaattttaat cccatcttac aaaacctccc caatttttac
    17821 accagttaaa aagacaccaa catcttgata gccagttgtt cgacgctctg tttgtcccat
    17881 atcatttgtt tcacgactat tcactcgttc tttacgaaaa acaaaataag cttcttcaaa
    17941 tgaaatacgc acctcttttt ctggtaatcg taatctttta tcctcttcag ctgtgagata
    18001 aacaaaaaaa gcaggctgtt cttctcgcga acactctgct tgtaattgaa catatcgccc
    18061 agacacacca ttaatttcct ttggtggatt aggttcccgt gaacccaata aaaatacttg
    18121 acctaaaaac tctttcttca tacgcaatgc tttttctgcc ataaagtttt tcctcctctt
    18181 aaaaaccaaa ataaattcta aatatttcta cattacaatc aaacaagcgg ttaaaaatcc
    18241 taaccgcttg ttcctcatga ctaatctttg gctttacgta ctttataaag tgttatacct
    18301 aaagcaatga ctaatactac taatccaaga accataagta tactacttgt ttgttcacct
    18361 gtttttggca acattggtac aacagtagct ggtttaaccc gttgttctgg tttcactggt
    18421 tgcggtggtt ttggcgcttc cacaatttga accgtttgat ctttgtttgt tagatctaca
    18481 ttgtgtttcg ccacttcttc aaacgtttct ttctcatctt ccgttttcgc ttggagccat
    18541 tccgcaaaac tcaagccttt tcctgcaaga ttgcgaccgt ccactaagaa ttcaaataag
    18601 aattccatca tttctttatc ggccgcaaag actttttccg catgagtgcc ttcaaatggt
    18661 gtgccgtctg gtgttaagta gccttgaaca attaagcgat agatttgacc aatcgcaaga
    18721 ccgtctactt tgacccattc aagcacagtt tgatttggca aggccaagat ctcttttccg
    18781 ccatttttat tcgtcgcttt cgtcgtaatg gttggattac tgattttgat ggtttggtca
    18841 ttgtcggtaa tatctgcgtg agaagccaat aatacgcctt ctctaaacag atcttcaaag
    18901 accacgactt ctttgcctcg caacgcacgt gcgtctagaa taaagtctag attgactgta
    18961 ccatccgttg tttctgccac aaacgttaag gtacttgtga cttcttttcc atctactagc
    19021 actggttttt ccgttacttt gtccattaga acaccgttga ctgtgtatgt ttttccaacg
    19081 accaaatcgt ggtatttcac agcgtctgta atggtgactt tcgttaatgg attaacctct
    19141 ttcaagccag tgggtttatg tgtagccgtt gtacgtacac ttgggttagt tactcgtacc
    19201 gtttgccctt tgtcgttgat gtctttatgg tttgctagtt cttcatcatt tctaaaaaga
    19261 ctttcaaaca cgacgatttc acgaccattt atacctgtca aatcaaaggt aaatggtacg
    19321 atcaccgttt cattttctgc tttggcaata aagccaacac tcgtttctac cgtatttcca
    19381 tgcacaagca agggttcacc ggttgcttta tccattaaga tccctttgac caagtatgct
    19441 tttcctggaa gaatctcggt aatttcaacg gtatcgttta aggtaaacaa tcctgttggg
    19501 tctgcgactg tcaatccgtc ttcaaagaca gccgtggtat gaacggttgg attattcact
    19561 ttcacacttt gggcttcatc gttgatatcc gcatgtgctg caacttcaat gccatcacgg
    19621 aaaagttttt caaaaacaac gatcgtttga cctttcagaa cactagcatt aaccacaaat
    19681 tcaaggtctt ttgtgccatt gactttgtct gcaataaagg ccaaggtact tgtgatttct
    19741 ttgccatctt gtaaaattgg cgcattcgtt gccttgttca tcaatactcc tgaaatggtg
    19801 tattcttttc cgacaaacaa gttggtataa gaaacactgt ctttaatgac gatcgtttct
    19861 aatggatcaa ccactttttc accatcggct ttatttgacg cttgtgtttc tagttttggt
    19921 ggaatcaagt aattacgtac agaaaccact aacgtttccc catcatctgg cgcattttgt
    19981 ttgaatgcaa ccgtgaatgc ttgtttatct gtatttggtt ggaaactttc taatggggca
    20041 ttttccaaga agtaatagtc atcggcaact agacctttca ctaaaatttc cccgttttga
    20101 tcagtggtat attcaccaat tgcttgattt ttaccgttat acaaggtaaa gttcacacct
    20161 gcgagcggcg ttttcttctt gttccattct tcatacttga ataattttac acttttccgt
    20221 gcttgacggt tcgcaaaatg gatcactttg atcggttctg tatcattggt aatcgagaac
    20281 actaatgggt tttgattcaa aacgtaattt acgggggctt tgatttcttc caaacgatag
    20341 cgatcttttc cataagtaag tgtaccgtta gttaggaaaa agcctttttc attggtttta
    20401 aagatatccg ttgtttctgt atcatttgga atctccattg tgacataacg attggctaaa
    20461 gtatcaaaaa tcttgaattc tgtattagca agtggaatca cttttcctgt ttcttgatcc
    20521 actttcacca ctttaagacg ttgttcaatt actttatctt ctaaaacata atggaaagtt
    20581 tgcccatttt cagaaattgt gacttcaagt ggttcaaata gtttataccc ttcttttcct
    20641 ttggtttcag aaagaatgta cgtatcaaag acaacggtat ttttaccaaa agtagcataa
    20701 ccatcattgt ctgtcacaac ggttttcacc actttgccag ttgtttttga cgtcaaagtg
    20761 atttcaatgc cagctaattt tggtttgtta tctggattcg ttgaatcgac taaatcttta
    20821 ttagcaactt tcactaaatc aatggttcct ttgatcactt gatcttttgc ggtcgcattg
    20881 acagtttttc caggttcaac aacaatttca attgcttcat cagaaagcac ataacctttt
    20941 ggcgctttga tttcttttaa aacatatttg ccaggatcaa gatctttaat ttctgcctgt
    21001 actttgccgt taattttttt caaggtaatt tctttaatct ttttcccatc tgcttgatac
    21061 aaaccataga ccgcattttc taaagaagct gcacctttat cgtggaatct ttattaggga
    21121 ttgcattgat tttcatgcca caagtcattt tgaaagtttt caaacttaaa ataccagcag
    21181 caatcgtttt gttttactgg tttttcttgt tcatctctgt ctttttaggc acagggatgc
    21241 atttgatcag tatcatctct ttttgggaca aaatcttaca tgcggtgagt ccaatggtcc
    21301 tgacagctct tggctatgga ttgattggtt acttgatgaa agatgctgag atatcaaaaa
    21361 ccagtccttg gttgttcctc ttattcggct ttgcgtttgc tggactttgc ggcgtgtttt
    21421 gggagttctg ggaattctta tgcgaccagt tcttaggcat gaatcttcaa cgttttgctg
    21481 cttctgatgg cacactgttt gtcggacgag cagcattgat ggatacgatg ggcgacttgc
    21541 tgacaaatac gataggtgct gccttaatgg gattgtttgc atggtctcaa agtaaaaaag
    21601 atgagcgtta ctttgaaagt tataaattag aaaaagtgaa aaatacctaa taaaagaggt
    21661 tgtgacagaa gcgggcagct tcaagaaatt tcggcttatt tttcgaagaa actacttctg
    21721 gaacactgtt tatttgaaaa aaggaggtct gacactagtt gtgtcagacc ccttttttct
    21781 tttatagtct caatggaaga ttagacgatt tcttctagct cttctgtttt gaaatgaagt
    21841 tgtccatcaa gtaaagtaat cgttactttt gatttaggca taacatgtcc tgcaacgatt
    21901 tctttagcta gtggtgtttc tacttcctta gtgataaatc gtttcaatgg tcttgcacca
    21961 tatgctggtt cataagcatt ttcagcaatc cacgttttgg cttcatcact gattgtcagc
    22021 aggatttctt gatgttccag acgttgtgcc aattgcgcca ccattttgtc aacgattcct
    22081 ttcacgttgt ctaggctcaa tggtgtaaat aaaatcgtgt cgtcgattcg gttcaagaat
    22141 tctggtttga agtttccacg taatagcgtg ttgacttgtt cagccactgc ttctggaatc
    22201 gttccatcag cagtcacgcc ttccagcagt aactgtgaac cgatattgct ggtcatgatc
    22261 agaaccgtat ttttgaaatc tactactcgc ccttttgaat cagtcaagcg tccgtcatct
    22321 aggacttgta acaagatatt gaagacatcg ggatgcgctt tttcgatttc atccaacaag
    22381 acgattgtat aaggatttcg tctgacagct tccgttaatt gaccaccttc ttcgtaacct
    22441 acatagcctg gaggagctcc gactagacga gacacagcat gtttttccat atattcactc
    22501 atatcgatcc gtaccatatg atcttctgag tcaaacaagt tctcagctaa cgctttcgct
    22561 aattcggttt ttccgacacc agttggtcct aggaaaagga aagaacctag aggacgattt
    22621 gggtcttgca atccagcccg tgaacgaatt accgcgtcac tgaccgcatc aactgcttca
    22681 tcttgaccaa tcactcgttt atgaagtgtt tcattcaatt taattagttt ttctcgttca
    22741 ccttctacaa gtttcgttac ggggataccc gttaatctgc caacgacttg agcaatctca
    22801 ttttcggtaa cggactcttg aaccatctta atctcgctgt cttttgcttt agcttctaat
    22861 tccttcaatt ctttttctaa ttgaggtatc gtaccatgac gcaatacagc agcgcgttct
    22921 aaatcatagt tattttctgc atcttctaat tcgtgttttg ctttatcgat ttcagcacgt
    22981 tttgctgaaa cagaattgac ttcttctttt tctgtttccc actgcatctt catcgcattt
    23041 gcttcttcac gaagttcagc taattcttct tgcaaatttt tcaagcgttt tttacttgca
    23101 tcatctgatt cttttttcag tgcagcttct tcgatttcca actgcatcaa acgtctagta
    23161 acttgatcta attccgttgg catagagttc atttctaccc gaatcgttgc actggcttca
    23221 tcgatcaaat cgattgcttt gtccggtaag aaccgatcag taatataacg gtcagataaa
    23281 gtagctgctg ctactaatgc gttgtcatgg atgttaacac catggtggat ctcaaaacgt
    23341 tcttttaatc cacgcagaat actgatcgta tcttccactg ttggttcttt gactaatacc
    23401 ttttgaaagc gacgttccaa cgctttgtct ttttccatat attgacggta ctcatctaaa
    23461 gttgtggcac cgatcaaatg taattcaccg cgagcaagca ttggtttcaa cagatttccg
    23521 gcatccatac ttccttctgt ttttcctgcc cctacgatat tgtggatttc atcgatgaac
    23581 aagaggatac gtccatcact ttttttgact tctttcaaga ctgcttttag tctttcttca
    23641 aattcaccac ggaattttgc tccagcgatc aatgcaccca tatctaatga aaaaatcgtt
    23701 ttatctttta aattttcagg cacatctttg cgtacgatac gttgagcaag cccttcaacg
    23761 attgccgttt tccctacacc gggttctcct atcagaacag gattattttt tgtttttcgt
    23821 gaaagaatac ggatgacatc acggatttct tcatcacgac cgatgattgg atccattttt
    23881 ccgcttttga cttgctgtac taaatcaacg ccgtattttt ctaatgcttt gtattgttct
    23941 tcttggtttt gtgaggtcac tctttctcct cctctcatct cttcgatgtt tttacgcaat
    24001 tctttttcag ataatccgtt tttattcaaa taaacagtta acggataatt ttttaatttc
    24061 atcaacgcta aaataacgac ttccgttgaa agaaactcgt cgccgaagct ttcacgtatt
    24121 tggtctgctt cattcaataa tcgaaagaaa ttctggctga ggttttgtcc atattggacg
    24181 tttccaccag aaacaactgg atactcatcc agtagacgat caatttcatg ttcaaaagat
    24241 tcgacatcca atccggcatc cgtatagaaa tttcgaccaa aatgattagg ttgtaaaaag
    24301 attttccata catgggcaat gtcgatatct tgatgttttc gagtgaccgc aatctgttga
    24361 gcttcagcaa tcgcttcttg aagcgtcgta gtcattttct caatattcat acaggtatac
    24421 cctcctaatt aaaggtaaga tcacttattt ctttgatctt tacaaaaact attatatcgc
    24481 tttggtcaat tttggtcaaa atatacacat agttttttga ctttttttct cgacttatat
    24541 aaatcttaaa aaaacaaaat tgattgtatg tatataaaaa aagagccaaa caaacgtaaa
    24601 attatcttat ccataacgtt tttctttgat ttgataaaaa gggtagatct tataaaagac
    24661 ctacccttga ttttctttat tctctttttt tacttctatt atttcttctt tgatcactct
    24721 tcgccgttca gcaatcacat acacaaatcc atagagaaat ggcaagataa aggaactgaa
    24781 acgatacagt aaaagcgaag aaactgcgtc aactgttcca acaactggtc tgaataataa
    24841 caaatagaca aattcaaagg aaccaatacc agcaggcgta ggaataaccc ctgaaagcac
    24901 tactgcaaag ctgataaacg aaatggtcag tagaaaatct attttaggat ggttttcaat
    24961 cagaatcaaa taaggaagta cataccaaaa tacaagtttt aacatattcc atagataaat
    25021 ccgcaatagc gcagtcctgt cttggataat ggtttggacc gtttccctta aagagtagat
    25081 ctgctgattg catgtatcca cccatttccg caaacgctca cttttaaata acttattcga
    25141 taagctgaca aaaaatattt gaacattcaa gctgacggac atcgccaata aaaaggcaac
    25201 aatcacgatc gtcaaaagga taccagcgat gataaaccag atcattgatg gaccattaga
    25261 ataaaaaaga gagaattgga tgaccaagcc agctaatgca taagtgatca ctgccagttt
    25321 gtacataatc atatggagtg ctgtcacccc tgctccctgg gatagcttca ttcctttttt
    25381 gttataaaaa taaatctccg agatcagcgt tcctgtacca aacgaaacga ttcggtaaaa
    25441 cgcaatatag ctagaggtca agaacccatc tttcgttgta aaattcggcg cgaaaggttc
    25501 agcaatttct ttgattgagc gcccttcagc gatttggtaa actgtcccta atataacagc
    25561 cgctgccaaa acaacaacac tggtagacag caattcggca aagatatctg caaatgattg
    25621 attgattaaa taataaataa tggcaaaaat cacaatcagc aaaagcagat tcagaatgat
    25681 tttagttttc gttcctttag acgacatctc ctgctcctta atggaaaaaa taaatgagaa
    25741 tcaaatcaac aagtacacct gcagcgaatc ctatagtaaa cttctttttc cgagttttat
    25801 gatggaaaac ttttcgagag atcaatcctc ccaaaccacc gcctaacagg ctgacaaata
    25861 tcaaattatt ctcaggaaca cgccagccgc tagttctagc ctgatgttta tcatacccca
    25921 tcagacaaaa taagtaaaaa ttcacaatga aaaggtaaaa ccacaaagga ttgtgtaaca
    25981 atacatccat tactcttctt ccaactttct gttaactact atttctaagc tttttcttct
    26041 ttctttggtg aataaactgt taatcctttt gatacaacag ataattcaac tggaagatca
    26101 tctgtcgtgt ctccatccgt tcgagtgccc acagattttt cctgcgcttg gattttcatg
    26161 cgtttggctg tgaaataagt aatgccgggg atcgtataga atttgcctct catgattcta
    26221 ggcaaataaa aaataaatcg gaaaatatct aaggaaggta cgatcgttac atgaaatttt
    26281 ccatcatcta gggtcgctga gtcgtcaaaa tttgtaaaac cgcccacgga gttagacatc
    26341 gtgactgtca acagttggga ttttcctttc caatgctcct cgtctgtttc taaatccaaa
    26401 tgatattttt tcttcttcag caataactta aaaaacttct tgataaagat ccacgagccg
    26461 taacgctgtt tttcttcttg actgatccaa actgctgtat ctgctaagat tccgattgtc
    26521 agtgtagaga taatgacttc atcattgact tgaccatagt ctattttccg tacattgcct
    26581 tccaggatca cgtcagcagc ttcttctttt ttgaggggaa tctcaagaac acgtgcaagg
    26641 ttgttgacag ttccacctgg aagtaatccg acatggtatt gagataatgt tttttggaac
    26701 gcttggacga tatgatgaat cgtgccgtct ccacctataa ttactaaagt atcagcttct
    26761 atggcttctg ctttcttgac taattccgca tcatcaatcg atgggccagt ttcagctagt
    26821 tctacatata attctggctg cttttctttt acataatctt gaaaccagcg tgctaatttc
    26881 tcaccctcat ctttccctga acttttgtta taaaaaacta gcagcttttc cattctttac
    26941 ctcctattta ctcttcaaaa aagagggcgg gacaaccaat tccattgtcc tgccctttag
    27001 ccttagacag atgacattcc atcattggga cgaacgcctt gtcataagct gttctttttc
    27061 gattttaact ctttgtgttc aattctgcaa tttttacaat cacgtctgtt gctttttcca
    27121 ttacttgtaa agaaacaaat tcgaatcgtc cgtgcatatt ttctcctccg gcaaatagat
    27181 ttggcggagg aatacccatg taagagattt ttgaaccatc tgttcctcca cgaactggtt
    27241 cgatcactgg agagatacca agctcgatca ttgcttgttt cgctaattcc acgatgctca
    27301 tatctttttc aatgatttct ttcatgttgt aatattgatc atacatatct actttgattc
    27361 gttcttgatc aaatcgctga ttcaactctt cttggatatg tgtgatttgt gctttgcgtg
    27421 cttcgaattt ttcacgatca tgatcgcgaa tgatataact catagaagct tcttcaggat
    27481 tcccatccaa tgccatcaaa tggaagaaac cttcgtatcc ttccgttttt tctggaactt
    27541 catcggctgg aagctgatta tgaaaatcga ttgctaactg tagagcattg atcattgtat
    27601 cttttgccgt ccctggatgt acatttttcc cttggatcgt aatatttgct tgagcagcac
    27661 taaacgtttc atactgcaac tcacctaaag gaccaccatc gactgtataa gcaaaatcta
    27721 catcgaattg ctcaacatcg aatttatccg ctccgacacc gatttcttca tcaggaccaa
    27781 aagccacttt gatggtaccg tgagggatag aaggattatt gatcaagatc tccattgcag
    27841 tcatgatttc cgcaatccct gatttgtcat ctgctcccag taatgtactg ccatctgttg
    27901 tgatcaatgt gtggccttca taatttttca aatttggaaa atcttttgta ttcaatatat
    27961 agcgttcttc cgcatctagt acgatcgtag actcgccatc atagttttca atgatttgtg
    28021 gattgactcc tactgcatta aaatctgctg tatccatgtg ggaaataaat ccaatggaac
    28081 gcacttcatg atcaacattg cttggtaatg ttcccataac gaatccgtta tcttcattat
    28141 agaaaacatc agctaagcct aactcttcta attctttttt caattcttgc gcaaaagcaa
    28201 cttgtgtctg agtcgatgga gtcgttttgc ttgttgcatc ggagcgtgtt tctgttttga
    28261 catatcgtaa aaaacgtggc aaaagatttt cgtacatagt attctctcct tttaattaaa
    28321 ttgaaatggg tttgtatttg tttcagaaac gaaaaagtta atatcccaat tttcttcttg
    28381 tttccaagat tcaaatttct cgataaatcg ttgcttgcat aacgattcaa tataatgacc
    28441 gggatcaatt gcaatcaacc cagcgctttg catatcatga gccgtatgat aatagatatc
    28501 tcccgtgata tagacatctg ctctttgggc gattgcttgc ggataaaatt tttcaccgct
    28561 tccaccgcaa atcgcaatgc gcttcacaga ggattttgca ttttttggct ggactattct
    28621 cagtccatct agttggaacg cttcttttac ttgttctaca aatgcctcta tagaaatttc
    28681 ttgcggcaat tcacctactc gtcctaaccc aaacatttcg actggttcat ctatagcgaa
    28741 aagatcataa gcaggttcct cataaggatg agctgaccgc atggcttgaa tcacttgttt
    28801 ttcgatagtt tccggcaaaa taacctcaac ttttgcctct tgaacttgtt ctgtcttccc
    28861 tactttccca atcgctggtt gtgcaccagc ttccggagta aatcgaccgt gtccaatcga
    28921 ggtaaaactt gtaccggtat aatcaccttg tgtaccagca ccagctgcag ctaatacttc
    28981 acgcattttc tgtgcatgat ccacaggtac ataaacggcc agttttttat aatgaatctc
    29041 atgagtcttt actaaataac tctccacttc aataccgaga agttcacaaa accagtcatt
    29101 cagtccatcc caaataatat ccatgttcgt gtgtgctgca tagacggcaa tatcatgttt
    29161 caacaaatct gcatacattt tttcttgtgg ctgatcagta accagccgtt ttacaggacg
    29221 aaagattgga ggatgtttag caatcagcaa atcgattttt ttcttgattg cttcttcgac
    29281 cacttctgga cgaacgtcta atgtcatcat tactcgttgg attggcttat ccaatgttcc
    29341 gatatgcagt ccgactgggt ctccttcttc agctagccac tgaggacaat agctttcaaa
    29401 cttttggatg aaagtgcgtc cgctgattgt catggcttta aaacctcctc aatcatttgg
    29461 atttcctgct cgatttgttt ttgacgtgcc tcttgattag ctgcttgttt gagctgttca
    29521 cggatagctt ttctttgttg aagctctctt gtccattttg atttgaagat ctcacttttc
    29581 tcttcaagca gaaatggccc gaacatcagc tccatttcat tgtaagtaac tggtttttgt
    29641 tctttttcgg ctacaatgat ttcatatatt tttttatttt cttcaagtat tttttctgat
    29701 tggattttat actgattttc ttgcagccaa gatcgtaatg tacgctctcc gatgtttggc
    29761 tgaaggatca aacgttcttg tccgcttaag cgttgattca acttgccagc ttctaggata
    29821 tctcggatca gtgaacctcc catacccgca atcgtgacag ctgtaatacc atcttgtggc
    29881 tggatagcat ctagaccatt tgcaaggcgt acggtgatac ggtcttctaa tccatctttt
    29941 ttgacttgct tacgtgctga ttcataagga ccttgaacga cttcaccagc aactgcatat
    30001 tcgatttttc ctcttaatat caatgcaacg ggtaagtaag cgtgatctga tccaatgtct
    30061 gctaaacgag cggattcagg gacaaagtca cccactgcgg ctaagcgctg agataaatct
    30121 aaatggttca tagcttcact ccttctagat aattatagca ttttccaaat aaaataagga
    30181 gactaggaat aaaaaaattc ccatatctcc ttaaaaaata taccttttcg ttctataaaa
    30241 caacattttc ttatttttga aaaaatgtta ttggttattt gttcaatgaa acatcaataa
    30301 tcgaatctcc aggaacttgc ggtgggatag acatcgtcat gatcggcatc tcaactaatg
    30361 taaattggac tttgtcaccg attttcaatt catttatgtc cacgcttatt ttttcagcag
    30421 tagcatttaa gatcactccg tcattgctga atgacgttcc catattcgct ggatcttctt
    30481 tggccatgac atcgacgagt ttcaactgaa gcgtttcttc ttctgcttct acttgagtga
    30541 tactttcaat cgttccgaca aatatgcttt gtctctccgt tttcgtactg cttgttttta
    30601 ctgtttgacc cgcatcaatc gaatcaacag aacctgtgtt gctatctgcg ctaccgcagc
    30661 ctgctaaaag aaaaaataga ccaactacag atatactaga aaaaatagcc ctcataaaaa
    30721 atcctccgtt taagtttctg cattacttgt tgcggtgatt gtctccggtc atttctgtcc
    30781 atataatgat tcgctgacct gcttttacta ctaggtcaaa tgtcagttgg acttgtcaac
    30841 tgttcaacca ttgcgtcggt tgcgaccagt catttcgatt tcttttgtca aataacgtat
    30901 gcgttccatt atccgtttcg cttttagcgg ctcttcatct ccacgttgag tgacggacaa
    30961 atgctgttcc aattcatcca ttgtaaaatt cgatgagaag aaggttggta actgttcctg
    31021 catccgatat tgaaggataa caccgaatac ttcgtctcgt atccaactac tcatcgcatc
    31081 tgcaccaatg tcatcgatca tcaaaatagg tgaacgtttc actgcatcta acttttctgc
    31141 cacttgatct tttccgattg cctgtttcat ctcaacggca aatgtcggaa aatggactag
    31201 cgtcgtggtg aatccagcaa tcgctaattc tctcgctgtt gctcctaata aatatgtttt
    31261 tccaatacca aaacttccta ctagatacag tcctttatga tacccttttg gatcagcagt
    31321 atatttctct acaaaatcta gggcttctaa gctcgcatat cctcgtccat ctgtacgttc
    31381 aaagttttca aaagaagccg attgaatatc ttttggcata tccattgctt ttactcggct
    31441 tctgatttct tcttgtcttt gccgtgctaa caatgcttcc gttggtacat aagtgacatc
    31501 cacataatga aaattcaacg tcagcttcgg ctcatagccg ggagcgatca tcgttggatc
    31561 gtttttttga tatttacgct tttcttgcac gaattcatac aatttagcgt aacttttttc
    31621 aatatccgct tgtgtcaatt cttcttggtg tgcgcttaga aaagcttgaa catccgcatc
    31681 atttaagact tcagcgatca tttcagcata cttttcttga taattgcgtt tgctgatgat
    31741 cctcttcaat tctttgccta cgtcttccac tagatatcac cctccttttt tgccaggtat
    31801 tctttaaaac ggcggtcaat ctctgctttt ttctcgctgc tgatctgttt ttcatctttt
    31861 ggctggttga cccaatcagg aagcttttcc cgtcgaacat ttcgcttgcc agtttgataa
    31921 tttgtttgct tcttttgttt tgattgtttt gcttgattac ttatttgccg aatgtgctgg
    31981 atcgcttctt ctgctgtggc gattttcttt tgtgcccatt catttgccac tgtatttaca
    32041 taactggcat ttaagctagc attattcttg atcactagta cataattcag caaaacattg
    32101 atcacgctac tggaaagacc tgattgagaa acaagatctt gcagtaacca gttttcttgt
    32161 ttagaaacat atccgccttt ttctgacttg attgcttcca gatatttcat cggtggaatg
    32221 ctctgtgctt cttttatcag ctgaagcgct gcgtttgtca aatgttcgtt tgacgagggt
    32281 tcattactgt tttcagaaac cgcaactgtt tcttttgttt gcttcaccgg acgtctctgc
    32341 attgccaaaa tggctttttg cagttctttt tcagatactt tttgttcact aaagtcataa
    32401 gattgactga tcagttcgcc aagtgtcaat tcatcgaaac cgtaaagctg atgatacatg
    32461 tcgacttgtt tgatgattgg atcatcaaga cttgcaatat gtttttttgc cagccaatca
    32521 ttcaaaaact gccaatcgaa tgtcgaatct gcttcaagta atgctactga ttcagattct
    32581 tcaaaagatt tattcagcga ttcgatgttt tcttgattag cagcgtacac tgcttcattg
    32641 aagcgataaa catctaaaaa tttttttgtg attttttgat atccctctgc tgtatgcctt
    32701 ttaggttcaa agaattgggt aagcttctgg aatcgtcgtt caccaacttt ttccagaaga
    32761 agaaaagcca gaacagagtc tttgaaaaat gctttaggaa tgagtggttc taacagctca
    32821 taaataaaac gaggtcccag atcactatct tctttaaaat aaacatccag taagccgatt
    32881 ccttctagct tttttcttgc atcataaaat tgcgggatac cgcagcctag actactaagc
    32941 agatctgcat gcatcccttc aggacctttg ccagattctt gagagatttc tgataacagg
    33001 gtgaaataga tactcaaggc ttctccgccg attagtggct gataaagata cagcaaggcg
    33061 ttcttgctgt cttctctcag cggagccgct tttcttcctt ggtaaatatt ttttggttga
    33121 agctctttcc aagcattttc caaggaaatg cctccttttt gtttcttaat tgttttcttt
    33181 attattctct ttattatttt cttttgcttt atccacgata tcttgcaact cttttaagaa
    33241 aacagacata tctttgaact ggcgataaac acttgcaaaa cgaatataag cgatttcgtc
    33301 taaatcaact aaatcttcca tcacatattc accaattaga ttcgtcgata cttcgttttc
    33361 tccgagactg cgtacgcggt tttcgacatg gttgacgatt tgttccattt gttccatagc
    33421 tacaggtctt ttttctgctg aacggatgag tcctcttaaa attttatcgc gattgaactc
    33481 ttcgcgttcc ccgtttttct tgattactaa taacggagca gcttcaattc gttcaaatgt
    33541 agtgaatcgg aacgaacaat tctcacattc gcgacggcga cggatcgcac gtccatcatc
    33601 tgcttgacgg ctgtcgatta ctcgtgaatt attatgttga catctgggac atctcatttt
    33661 gtctcacctc ttgcatcgca ttttatataa aggatgtgtc tttctttaca actagttgta
    33721 ttataacacg aaacaaatca caaacgcgac tgtcctaccc aaaaaacacg gatataagaa
    33781 caattttttc tactttcatg cgtaattgtg tcccctgtcc ttactaaatt tcaattttcc
    33841 aatactgatc accttgatta ctgagaaata acttacacaa aagctgattt agtcatctag
    33901 cacaaaaaac ttgaagcaga tgaacacctt ctcatctgct tcaagtcaca tctcgatttt
    33961 ttactatttt ataacttctc ttcgattcct gtatagtgtt tcattcgctg ttcctcgatt
    34021 ttttgctcat cgggaatgtg gtcactttct gggagcggtg ttttactacg atcaggtgtc
    34081 ggattttttc gttcttgagt caaatcttgc cgcttcgctt cttcttctgc ctgctggtct
    34141 tctatttcat cgattcttgc ttggtactgc ttttcttttt cttctgctgt ttctgattgc
    34201 gtacgacctt catcgattag attttcttta ttgagcatct cgccgatttt ttcttttgcg
    34261 ttacctacga ctttatcctt ttgatttttt aatgatccca tcgctatccc tcactttcta
    34321 tatactcagg atagcaaaat tgacacagat actcaaagaa agcgattagc aaaaagccaa
    34381 ttttcgattt gtcccacaag tttttctttt gttccattgt tgtcgaacaa aatatccgca
    34441 cgctgctttt tttcttcgat tggaagttga ctactaattc tctgctgcgc ttgttctagc
    34501 gtcagttgat tacgtttcat caaacgctga agctgagttt ctggcgtagt ataaacgaca
    34561 gctactgcat ccatatagtg gtcataatga ccttcgtaga gcaatgggat atctacaatt
    34621 actaaaggat gattggaact tagagaggcg atttgatctt ttatcgcttt tcggataaac
    34681 ggatctaata gctgatcaag tttttgccgt ttttcctttg atggaaaaac aatcatccca
    34741 agtttccctc gatctagttg cccatcaggc tgcaatacct cttggccaaa cactgataca
    34801 attttcctca gagcaagcgt tccaggctca acagtttctc tggcaatcac atcgccatcg
    34861 atcaaaggaa atccatgaga ctgaaagact ttggctgccg tacttttacc ggtagctatt
    34921 ccacccgtca aacctaaaac aaatcctact ttgcgatttt tagcctttga caattcggac
    34981 aatagtgcgt ccccctttgt gccacttttg ttttcacgat cggcgttcca caacgtatac
    35041 atggtttgcc agtttgctga tagacatgca gtgctacttg aaatccgcct gattctccta
    35101 atgcattcaa ataactgcga atcgtggtac ctccggcttc tattgcacga tccaaaacat
    35161 caatgatcga tagacgtaat tgttctacct ctttggggcg cagtgtgttc gccggttgtt
    35221 ctggatggat cttcgcttcc cataatgctt catctacata aatattacct agaccagtca
    35281 ctagacgttg gtctagcagc aatggcttga ttgctttgtg ggactttttc agtccatttg
    35341 cgaaatctgc taataagaag ctatctggca aaggctcagg tcccaatttc atgattcctc
    35401 ggtaagttgc acttgctcct ttttcgacga ttgtcatacg accaaatttt cgtacatcgt
    35461 tgtagcgaag ttggcttcca tcctcaaaaa agaaaagtac atgcgtatgt ttatcgattg
    35521 gtgtattttc tttcgtaaat tgatattttc cttccattcg caagtgtgag atcagttcac
    35581 aatgatcgag atgaaaaatt aaaaacttcc ctctacgtcc aatggattgg atggtttcgc
    35641 caacaagaga agcctcaaag atgggtgtct ctggttgctc gatgatcttg ggccacaaga
    35701 cctgaacttt ttgaatcgtt tttcctacta ctaaccgttc caatccttta cgaacggttt
    35761 ctacttctgg taattctggc attttttctt ttcaccttca ttatattgct ctgtcttaaa
    35821 caatgtttat tttgcttcgt accacgtttt tccccaactg ctgtcagtga tcagtggtac
    35881 atgaagagaa acagcttgtt ccataacttc cttcaccaat ttatctaatg attcaagttc
    35941 tttttccggt acctcgaaga caagttcatc atgaacttgt aacagcatcg tagcttgaag
    36001 acctgtttct tttaatcgtt tatccaattc gatcatcgcg attttcaaaa tatcagcagc
    36061 acttccttgg attggtgtat tgatagctgt tcgttccgca aaagaacgga tattgtaatt
    36121 tcttgaattg atgtctggca gatatcgacg gcggtgatac agcgtttcga cgtagccttg
    36181 gtcttttgct tcgcgtacga ttctttccat atattctttg acacctgggt atttttcaaa
    36241 gtacgtatcg atgtattgct gtgctgcttt tcggctgatt cctagatttt gtgaaagtcc
    36301 gtaatcagag atgccataca cgataccaaa attcactgct tttgcctgcc tacgcatatt
    36361 tggtgtgaca tcctctgcct tttcgattcc aaatacacgc atcgctgtgc tggcatggat
    36421 atcttgacct tctaggaagg cagctttcaa atgttcatca tttgagatat gcgcaagtac
    36481 gcgtaactcg atttgtgaat agtcagaaga ataaatcagc cagtcttttt ctctaggaac
    36541 aaatgcctga cgtatctttc tcccttcatc taatcgaatc gggatgttct gcaaattagg
    36601 atcaacagag cttaatcgtc ctgtttgggt caatgtctgg acataacggg tatgcacttt
    36661 tccatctgat tggatcactt tcagcagtcc ctcgacatag gtagattgaa tttttgcaat
    36721 ttgacgatag gtgaggatat cctctacgat tggtgcttgt tcacgaagct gttccagtac
    36781 atctacggct gtggaatatc cagtttttgt ttttttgata acgggtaatc ccattttttc
    36841 aaataagatc actcctaatt gctttggtga attcaaattg aattcttcgc cggcttcttc
    36901 gtagattttt tgttcgatct ctcttaagcg agcagagaac tcgcccttca tttcttgtaa
    36961 gcgagtcgca tctactttga tcccgcttat ttccatctct gccaaaatga tagacaatgg
    37021 cagttccatt ttccggaaaa gatcttcttg gtttttttct gccagttctt ggctcaattt
    37081 tggtgtcaac gcattgattg cagctacttt tcgcgctaaa tgagcaaaaa agagttcctc
    37141 ttcttctggt aaaccttttt tcgccccttt gccgtataca gcttcatctg attggatatc
    37201 gttgtatccg taatgagcag ctattccttc gatatctgtg cttttttcat tcgtatcgag
    37261 aaggtatgca cctagcaaga catcaaaatc gattcctttc gtttttccag tatagcggtt
    37321 taaagcaaca taagttcgtt tcgcatcata tacttttttc agccgagtcg gatcagtgat
    37381 ccaagaatgg aacgctcggt tttcgaatac agatagatcg ttcgtgacat aaattttctt
    37441 ttctgtcccc cacgctactc cgacgatttc ctctgtatga taattgtcgc ccatcatttc
    37501 cacgtacaac gccatatccg tagtaaacat ttcctctttg aattcatgaa cgacttcaaa
    37561 caaaatatca tccattttta cttcttcttc tacgatattc aatttagaaa ggaactgatt
    37621 gaaatccatt tctttataaa acggaacgag tttatcgaga tttttccctt catacttcaa
    37681 tgagtcgata gagacatcca caggcgctga agtattgatg gtcgccaatt ttttcgataa
    37741 gaaagcctgc tctttgtcat ttatcagatt ttctttcatt ttgctttgct tcatttcatc
    37801 gatatgttca taaattcctt cgactgagcc atattgtttc aatagcttga tagctgtttt
    37861 ttcaccgatt ttagtcacac cggggatatt gtcagaggca tctccggcta gtcccttcat
    37921 gtcaataatc tgttttggcg tcaacccatc atatttttcc gctacatgtt ctggtgtata
    37981 gctttcgata tcgctgacac cttttacagt gatatccact tttacttctt tactagctaa
    38041 ttgagtcaaa tcccgatcac ctgaaagcac gacgacatca aattgatctt tgtctacttt
    38101 ttctgccaaa gtaccgataa tatcatctgc ttcataattg ggcaattcgt aatactgtac
    38161 ccctagtcct gtcaacaaat cacgtatata tggcatttgt tctttgaatt cgccaggtgt
    38221 tttggatctt ccacctttgt actccgcata catttctgtc cgaaaagtcg tttttcctgc
    38281 atcgaacgca accagaacat gagtcggttg ctctttttgc ataacatttt caaacatcgt
    38341 attgaatgca tagattgcat ttgtatgaag accgtttcta tttttgaaac gttcaagaga
    38401 attgtgaagc gcaaagaatg cgcgaaaagc cacactgttc ccatcaacga gtaataattt
    38461 attttttgtc atcttcttaa ctccttactg taaagttctt attcattcta acaaagaatc
    38521 ctgcggaatg cgaaaagaaa aagcgggacc ataccaaata attcggtata gccccaactg
    38581 atgaattttt ttctttttta gttgttccgt ccaaagattc tcagaaacgc caagaacaag
    38641 ttgataaagt ccaaatacag cttcaatgcc atgaatacag caattccact atgtgctgtt
    38701 ccgtttgtct ggacatagat attacggatg ctttggttat cataagctgt aatccctgca
    38761 aagatgacga ctaacagtag ggagatgaac agctcaacta cgctacttct caaaatgaag
    38821 atgttcaaga ctagtgcaat gatcactccg attaaagctg cctgtcctgc tcttccaacc
    38881 ccgctaagat ctctttttgt tgttactccg acaacagaca tccccatgaa catcaaagta
    38941 gctgtcaaga aagcttgcgt tactgttcca atatcgtagt atgcaagagt aaccgctaat
    39001 gttatgccat tcaaaagaga gtaggcaata aatccaccga ttgctaagct cggattcttt
    39061 tgtgctttta cgcctagaac cattactaaa atcagttcaa cgatccacag acccacaaag
    39121 cctagtggaa aattattgat aaaagttgct aattgcaaag gaaataccca aagagccaag
    39181 taagaagtga ctgcactaag ggcaagtccc atacctaaaa atccataaac ttttgcataa
    39241 aaacgattga tacctgacat tgatgtactt ggattattca ttcaattcac cttcactttc
    39301 gattgctatt tccaattcag gaacttgtgg cggttggacc ataacgacag catccaacac
    39361 acgatcttcg ttcgtattct ccgcttctac agaaatcgtc accacatcct tcatcttatc
    39421 tacttttatg acctcaaact gaaaagtcag tgtttcataa tggaaaaccg gttcaataaa
    39481 attgacagaa aaattgacaa catgtgatcc tggtccagga agatgctttg aaattgcact
    39541 tgtgatgatc cccatcagca tcactgatgg aacgattggc tgttgatatt ctgttttttg
    39601 tgcaaagtca tgttggatat acaaaggatt tgcatcattc gtcaatccca aatacagcaa
    39661 aagctggtta tcttcaatag attctgttaa ggataacgag tcgccttcct cgatttcatt
    39721 tattgttttt cctagttttc tcggcttacc tatgttcaag atagaaaccc tccagtttat
    39781 ttttaatcat acattattgt accaaaagta gcgtaaaagg caagttctgc tcccttgatt
    39841 taacagattc ctatagttta cagaggtcgt gaaaaagctg tcctgcatca aataataaga
    39901 acagccaaga aaa
//
LOCUS       DACDLM010000021        38341 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.021, whole genome shotgun sequence.
ACCESSION   DACDLM010000021 DACDLM010000000
VERSION     DACDLM010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38341
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.021"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..340)
                     /locus_tag="IV356_001120"
     CDS             complement(<1..340)
                     /locus_tag="IV356_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014822.1"
                     /translation="MTNEKNESIGLNAIKRKNKTQRPENIVPENSEALNNTTDSGKIL
                     EQSKKRLTTKDLPKSIRMPLDTHTAISTIATIEDKKIYETLNKIVEFYINNMNPANKK
                     IVKNSIKAVQN"
     gene            complement(354..1160)
                     /locus_tag="IV356_001121"
     CDS             complement(354..1160)
                     /locus_tag="IV356_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP9014823.1"
                     /translation="MTKVLTTGNFKGGVGKTTNAVLTAYTLSNKGYKVLVVDLDPQAN
                     ATELLFATMTNVYKIKPEFKETLFVSIQNNKISNSLISVKENLDLLPSFTDLEKYIDY
                     LAELYDDDYSKDTHFSNLLNEIKENYDFIIIDVPPQLNKFTNSALVASDYVIVILQTQ
                     ERSLKGAEKYIEHLIQLNNDYGTEIDILGLLPVLVQNGNDLDLDIIEDAESLFGKSNI
                     FNTKIKTMQRLKRYDRTGITDNPKDIHDKRVQQVYESVSDEVIQRINLLG"
     gene            1589..2632
                     /locus_tag="IV356_001122"
     CDS             1589..2632
                     /locus_tag="IV356_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HAP9014824.1"
                     /translation="MSEFKYYKSKEIYREKYYQMPKVFFTNEKYLNLSNDAKITYMLL
                     KARFDYSVQNKWVDSEDNIYFIYTIEELMRLLNCREGKISKIKKELESAGLLKQKKGR
                     IKKANGKIETTPNLLYLGKPEVTSEDVFKINEEERLIPNPVNAKIANTEKTDEIKDIP
                     VNAKIANTEKTNDTNDFSVTAKIADNILYSNNSLDTNRHNIDTDKDQLQDQLLLENFV
                     DIMTDSSFDTFIPTNVLKLIKTFSNSYSEAQQTVKTIHNAKHKAQESKNTIIVYEEIE
                     YFGIDADKGLYMTLLKAYQKQKTEKVDNLQNLIFIYVKNWFAEKAIPAKLAHEQTTET
                     DSLPAVNLENWLD"
     gene            3506..3898
                     /locus_tag="IV356_001123"
     CDS             3506..3898
                     /locus_tag="IV356_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgR"
                     /protein_id="HAP9014825.1"
                     /translation="MELKPRNLKQITCEFVLFNRQHIKFSNRTIKRKITDFSGKEIIL
                     YAKKLSSEQELACFFDQIKAVYVDGKIVACRGCSELPLIVSNHVFSKMKARQKLLRES
                     KIRYREMQKEETKKRKSVACKKYKRISA"
     gene            4695..5081
                     /locus_tag="IV356_001124"
     CDS             4695..5081
                     /locus_tag="IV356_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014826.1"
                     /translation="MNRIRFGKSNKNEFSSIFKVNVGIALVFFPLGIWGGMRVQCEQS
                     YFDNTIDEVYFEYDLATHRNYNPKESHEVSLRRVQYLTWDLYPLLKYPESVTSKLFYI
                     DKRNNEKVEKAWVTLLKLQKIALEEK"
     gene            5105..5302
                     /locus_tag="IV356_001125"
     CDS             5105..5302
                     /locus_tag="IV356_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014827.1"
                     /translation="MEWLKNEKELFQFLSDMKRKNQVANLDNYIKWIKDQSVQIKQDR
                     ESSNLNIKIAVTDKQNNILIY"
     gene            5313..5585
                     /locus_tag="IV356_001126"
     CDS             5313..5585
                     /locus_tag="IV356_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014828.1"
                     /translation="MIEEKKKVLYSNKPEFKKLVMQYAKKNIGRSITYDTFIKWLDKY
                     GYDLSQYDTCWQAVFKSLLQRNFQIDIAYRKTKECQLITVFQLNKS"
     gene            complement(5697..6116)
                     /locus_tag="IV356_001127"
     CDS             complement(5697..6116)
                     /locus_tag="IV356_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014829.1"
                     /translation="MKKSHIITLATIFLLCVAAFFFFTNSPKNNKHITASTATTESTI
                     KTETVYPYLNELKQLQGSDIEILGKTQITTVLFQNKNIAVLTTENNKEIQLPLIVTDK
                     KNNLFEIPSLTYSKKNLKVGEVFGLAKKDNHYLAYKL"
     gene            complement(6162..6404)
                     /locus_tag="IV356_001128"
     CDS             complement(6162..6404)
                     /locus_tag="IV356_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014830.1"
                     /translation="MNITNIEELKEWIETNLVTKQEAIKITEQSPKGFQQSVRTNVIK
                     PFYESKEGKGPSVVRLYLKSDIEAYAKQLKEKKQKP"
     gene            6555..7451
                     /locus_tag="IV356_001129"
     CDS             6555..7451
                     /locus_tag="IV356_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP9014831.1"
                     /translation="MKLLKVLAVGVTVGGIALAINQEKVSAAEWTPRTVQQISADIAK
                     TNGKEYTIVYGDTLSGIAQATNQTVQSLAEKNSIANVDLIYAGNKLIFDGNVVTVQNP
                     QGETIAQTVVQDSDKIDPTKPVGQPVQDTTSNATNSADQSVAPTTPAGDSGANTPEQP
                     VQPSTPSDNGNQGGTVTPNPDQNQGGNNNQDNQGNQGGDTGNNGNQDNQGNNNGNNNN
                     GNNNGGNEGGDVTPPQPVEKWTVWYSASDEANAAHNIEKGTKVFDTEAEATAWIDQYA
                     DGLLAQGITSNSYGVSSFLVQE"
     gene            7705..10824
                     /locus_tag="IV356_001130"
     CDS             7705..10824
                     /locus_tag="IV356_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HAP9014832.1"
                     /translation="MILGALAMFLGFGLSSQSVNADNITMKPGEKGDIYYDASNVYTM
                     HGTKHGQPWSDATAAMAVSPNNGATDRIVFCIQPGVPFINTNNPDYEAVAVTDIPKDA
                     QIASVIWNTFYAFGTNFTNEDRIVTQAVIWELLPQYGIKVDSISGIPDFQAKKQKLYD
                     GIKEYKRLPEFNNKTIDLTFGETKKLTSSVDLNSFETQVSNSAKVNWNIAADGKSVDV
                     TPTDPNVTGGSISFKRSYMEGTPIALEKTGSQTVYLPSVKDPNNYSVNFRIQTVGDIT
                     IKKVDKETGEVVPNTQFKVEFSGKGAPSAQTVTTDKNGLATIKGINHGVHVKATEIAV
                     PAPYVLGSAIGDSDVVEGDVVAGQTVTLTQRNQKAKGQILIEKSGVETGKDMWNANYT
                     LAGNVFEIHEGNETGTVVRTITTDDKGHAETGKDLPLGTYVITEKTASNGFANTFKPV
                     TVKIEYANQTTAVIVKGAEGTNQEVVGSTLLTKEDAETGKETQGRATFDGAQYGLFHK
                     DGTPVKWSENFKPTTSKGNKLEGDEVKFELSDEEQQASVEHLALGDYYWQELVAPEGY
                     QIDNTKREFSITYKDQETKVIETQSTSQENVIKFSLDGFKYVDSKSGDTKTGYNGIDF
                     TLTPIDPTKGEQRKVTTETDENGYDGYWAFNEVPYGDYKMSEVKAPEGYKTIKDLIIN
                     SKFDAEKREYTFTITEDGQKEPIKTLTVPEAKINEGSNVIHLSKLFLTNKVKEMPTIR
                     TKATVDGEKTFTPSKETPMQDVATITNVEKGVEYTNKIKLWRIVNDDYDNAKVVWEGS
                     HDFVAEGDKVEDVIKQMVDTSKDDNTVSYVFTEELFIKDGAKVAEHNDLTNKEQTIRP
                     VEPELPTIETLFVTKDGGKTFDPTKDQTLIDEVKATVPKEDIGQTFYYVTQFHKIDKN
                     GKVTVVGTDESEHKAGEMTYEFKAVYNYKANTLKDGEKLVATHIAYTDKEHKNEYAKH
                     FDLKNEKQTLTAKTPVTPATPTTPQKSIPQTSGSLVNIGSLIVLGIAAVAGAALYVTT
                     KKKVNKNEK"
     gene            10873..11910
                     /locus_tag="IV356_001131"
     CDS             10873..11910
                     /locus_tag="IV356_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAP9014833.1"
                     /translation="MFLGKGEINIVKKIIKALPLLWLLSSLILAICGFYGYTVLLRPE
                     NTIKQAQQITHPIQSEKEIKEIQQTTIGKATYNENQIQPVTPTDYAEAQLSYEALVNQ
                     WGIGSLYIPSSGIYSKILAGMSNDNLMVGLGTYYPNQLLGKGNYVLMAHNLVQGGGVL
                     RNLPQSSVGSTIYATDFSKIYEYEITTNKIVNQSEGKLLDIPQEGDSPLMTIFRCEGG
                     LHTANRALIQARYVRSYSAENGSHDIKQALGLETTRNKTVNKQRLNDQQATSTNRTEA
                     AKESITPDKDTKKAKQTNKIEWRFTEKKAIYSNFQVFSILVFQLANAYPILIGLVFLV
                     GLSSCILLNRI"
     gene            11997..13523
                     /locus_tag="IV356_001132"
     CDS             11997..13523
                     /locus_tag="IV356_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAP9014834.1"
                     /translation="MKKKHISKVASAVLLSQMLLTTPLQVLADEQLSTTTSQSSTMNN
                     QSEESTSSSDEQTGTSTTQTATDSTESSADQSTTEDTTTSSTDTTSTTESSEKPTEDS
                     TTDSTSTTESSSESKPDETKPSETKPSESKPEKPNTGSSTNESQTQPTTEPSNNQQAP
                     SVAPNNQAKATNEGQQAKPAESESKPYHQTPTAPIQELVPSSKETAEGNIHFEKDESV
                     ESFVRKIGEPARKVGQENDLYASVMIAQAILESASGQSQLAQAPNYNLFGIKGTHNGK
                     GVSFATQEDLGDGTLYTTQATFRQYENYEDSLNDYAQLLKEGLTGNSQFYSGVWKTNA
                     KTYQEATKFLNGRYATDTKYDQKLNGLIETYHLTDYDKEVAGPQLSKEGYIVPVKNYT
                     ISSPFGTRGGEFHRGLDLAAAQGEPIYASKAGTVVKAEFHPSWGNYVAIEHEDGTTAL
                     YAHQQEYQVKVGDKVKQGQIIGYVGSTGNSTGSHLHFELCLDQSLSQSQLVDPETVLF
                     "
     gene            13702..14109
                     /locus_tag="IV356_001133"
     CDS             13702..14109
                     /locus_tag="IV356_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014835.1"
                     /translation="MTNRNEGITIYLTIGKEVKLNFDSENNLSSIRLSINKVAELFGN
                     KVVNEESIFYVSTVALVTKSNYKTFISVVGGKQVISGDAVYEEVMIDQERTSNKRGNK
                     NVYEQGYFEFFVSEEDKIPKEKLILPYNVKKRR"
     gene            14133..15287
                     /locus_tag="IV356_001134"
     CDS             14133..15287
                     /locus_tag="IV356_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HAP9014836.1"
                     /translation="MNITVKELGEPIELEDYLEEYKFQVIFLLKNMTFIDRKDNRVRQ
                     LFNMELIRAETKWYSFYQKNHRPPDYNFLQEEITSFGVNRLPMFDRRNEGRVNDELSV
                     DNFVHYHIQQLKLEKILSPAFFEKNDLRFMERYAKNKAKAYFNERDQYIKGYESFRIS
                     RNKIMQRAGYEQLKYEFVSDNMVQGYFKEEVAKMAANDERVAEFVFDEGKSLMRNLTQ
                     KMSRGGVSIVNGSTKAVTNQIKKQRTTGKQRYNQLKKHGALEHIDVSKTDLKPLANEL
                     KKYKVDFAVKRNKETGKIHVFFKAQDRDTLNLALENVLQKFTNEKEQNREQQQEKPNK
                     DIEKSSVDDKDKDKSLTKKLDKLEDKAQEINQQREQLKENTKNKTKGQER"
     gene            15362..17158
                     /locus_tag="IV356_001135"
     CDS             15362..17158
                     /locus_tag="IV356_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HAP9014837.1"
                     /translation="MVYFSIPQNTDSSWINVVNEAFDKFLEPKTFTISPFTFSKIAMK
                     GGAIIAVIVLLIDLYIISGKKNLRMGEEHGSAKWGTSKDIAPYVDKKFKNNLLFTNTE
                     RITIETKLKKNKEYERNNNVVVVGGAGSGKTRFYVLPNLLQMHSSYVINDSKGGILSD
                     TAAIMQQNGYRIKVFNLNTMKNSDGYNPFHYIRRTEGDCEIDILKVVNNLMKNTSDPN
                     KKGGDSFWDDAQRSFLAAIFHLLILKGKPEEQNLGIVADLVRRARVKEDDEEYISSID
                     LVFQELEQEQPSCFAAKQYQNFKMAAGKTAKSILISLGVRLSPFDVPDIRKLTSTDTL
                     ELDTIGDRKTVLYIILPDTHTTMNFLASMIYQQLFDTLVYKADNVYNGSLPIPVRCLL
                     DEFANTGQIPDFENVIATTRSRGISVDVILQNLTQISKKLYKDSWETIIGNCDSFLYL
                     GGNEQSTHKYISTQLGKETIDVVTYNESRGTTGSFTKNSQKQGRNLLDPNEVREIKGG
                     KCIYMLRGTKPFLSDRFKLERHPLFKKLKETPSGYMYQSPLDQEEFIANNDPIDFELS
                     KNVDMKEFLKHTEIETYDFEDEEIETINLDEL"
     gene            17175..17375
                     /locus_tag="IV356_001136"
     CDS             17175..17375
                     /locus_tag="IV356_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014838.1"
                     /translation="MGTFNAIIDILSKYAIVGGGLYAVWGAVVLGGALKDHNGPQMQS
                     GIWQIVGGALIVAAAALFKTIV"
     gene            17404..18255
                     /locus_tag="IV356_001137"
     CDS             17404..18255
                     /locus_tag="IV356_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014839.1"
                     /translation="MMDGFLTWCVESILEVISFSSKTSHLTSNLENFSPQLYKYSTTI
                     LDSVSKPIAFSILALFFALELQRISNRVETNGGGQTGFEMIFKSLVRLGLCKLAMDQV
                     SLIMRAIMDITGYMTDKINHLGMGNKEVSDMLDAKKILAPILKEGLMFKVGVSTVLII
                     ALLITIGSIVIVQVVVNMRFIELYAFLAMSPIPIATFPNDEWSSIGKNFLKSFTATAL
                     QGTLIFMVMQFYPYLLSSAFSDITNSGSASETFLMTLIGIIGNSVLLIFAVMATGRWS
                     KSITNAM"
     gene            18520..18891
                     /locus_tag="IV356_001138"
     CDS             18520..18891
                     /locus_tag="IV356_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HAP9014840.1"
                     /translation="MAIRVKVPKEIKDYQEKLMGGMSVRQLVFFVLAVLISVGVTAYC
                     VLVLHMSVDAAGYIVIPLLIPIVAFGWIRKEGMPLEKYGKIILNYYSKTGIRIYQTKE
                     RSNLNDFRKKRFQKVKETTKK"
     gene            18839..21289
                     /locus_tag="IV356_001139"
     CDS             18839..21289
                     /locus_tag="IV356_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAP9014841.1"
                     /translation="MILEKNDSKKSKKQPKNKQAKKVLKILAKQKKQRGKNQRRDAPP
                     LSSQRSLTYKAMYENGVCELKEGLYSRTFKFSDINYAIADQSEQELTFSSYCELLNSC
                     DSDTSLQISIINRSKDKKQFEKDLSYELVDDGLDVYRKEMNHMISNKIKYGNSSLQKE
                     KYITFNQRAKTLEQAIPALNRLQGDLEDQFSEMGCEVEELSGIERLRVVNDILRPNKK
                     LHFEYEDLLFSGLTTHSAIAPDSFDFKYRKDRFKMGDYYGQVLYLRNYPAELSDKLIT
                     NITDIPTNLQITLHIEPLDQQKGLDLVKTKLSFMEQQKIDEQKKAARSNYDPNLIPME
                     LRRSMDEAQELLDQMQGDNEKLFSFTFLVMAVDKDERKLDDTIEQILTAGRKNDCEFA
                     KLNYLQEEGLNSTLLWGNNFVPIHRTLTTASTAVFIPFTAQELMQPNGKYYGLNSVTK
                     NLVTLDRRKLKAPNGFILGTPGSGKSFATKKEMTAVLLSDPDAEVIVIDPEREYTPLA
                     EALNGEVIQISAGSKNHVNPMEINNDYADDDDPVILKTDFVLSLCEMLVGGNIGLSPT
                     QKTLIDRSCRFAYKKYFENGSGMPTLKDFSNILKDQPEDEARQLAVELELYTEGSLSV
                     FSHQTNVDTSKRFIVFDVKDLGKQLRSMGMLIILDQIWNRITSNRNAGRRTWVYIDEI
                     QLLFSNEYAENYFFELWSRARKWGAIPTGITQNVSTLLSSLNAERMLSNSDFVLMLNQ
                     SQRDRERLGELLHISSRQKKYITNAKEGAGLMYAGDSMIPLYDEFPKDTNLYKVMSTK
                     IEDVYKYQNEQREQGTTV"
     gene            21286..23133
                     /locus_tag="IV356_001140"
     CDS             21286..23133
                     /locus_tag="IV356_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HAP9014842.1"
                     /translation="MNTDFRERIIRKQKTAKKFVVNRDNNQFKKKIVSTDYTKRAKKA
                     NHSGKIKSSRGTSYLIKKDSAKNVVKDVNSKAQKNGVEQGNATAELETSKTIGRGIKN
                     STKATKTVAKTTTKVTKKSKELIQTKASKKEVLTVVKKGSKKGLVNTSKAAKDTVINE
                     IQEFRGDSESQGINEAIQLKDFIDTGISGAKKTKKAANTAKKSSKALTKFGKSSYKYT
                     QRIAEIGIRRVQQVLSKEVAKALIAKLAIPLTLAVLILSIVTAVISTVNIFNFGAGDC
                     DTSANYDNITTKDIESNAKSIYSIIRKEIPESTPQGISGALGAMQFESQLNPSAVNPS
                     SGATGIAQWLGSRLTSLKEFAHKKGKKETDLGVQVEFLLSELNSSYYQSSKKILAMTD
                     VHEACKEWVMKFEGLSQDSSQWYLDQRNSYADHWYATLGTSDPIAEGTISNGADSELN
                     TLTCDLESDGGDIMEIAKSWLGWFHYDQIHPAPDLGTDLKNPNKNGRTDCSGFVWLVL
                     NKAGYKVPANMQWFTGSMASDARGSHQYLKQISETEAKAGDIVIVNQGAGAGSNGHTG
                     ILTEKWRGKDTKIIQEGGNGDSVNIEAFGTSFMSLLDGGDVVLARPIKK"
     gene            23153..23782
                     /locus_tag="IV356_001141"
     CDS             23153..23782
                     /locus_tag="IV356_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014843.1"
                     /translation="MLNRKSATITIFVLIVSVFSLSIGLNIKQELTVKTANSKIAALE
                     KKNDILKRETKDQKSRISKLEDENNKMIETQIVNKDGDVYKEFTNIATKYFKSRFNYD
                     PKTYKESKENVRDLISEELYKKFSENQLTYGDSNNVSSRLDNLKIYSGSLINQKTITG
                     LLIVDYESKLGETDWFKNSEIYTVQYDIHAKKLTKIQSLGSVLRGDMIE"
     gene            23775..24149
                     /locus_tag="IV356_001142"
     CDS             23775..24149
                     /locus_tag="IV356_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HAP9014844.1"
                     /translation="MNKKIFSICVLIFTVSIIFLADHSYIKYIEAQNDPVYLDESNQE
                     KIVFYRNDCRDCEKIMPYLIRHNFLYHDLTFVNMNNKENKRYIKEYGLTSVPTIISLK
                     QRYVGTDISKIKTLVMSKGDDF"
     gene            24149..24382
                     /locus_tag="IV356_001143"
     CDS             24149..24382
                     /locus_tag="IV356_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2968 domain-containing protein"
                     /protein_id="HAP9014845.1"
                     /translation="MARKSLTERIQQKKEEATKLEKRIQEDQYKLEKLTKQIRDLEAE
                     QVLAILDNHKLSVKDLNKILSKQPDNNNFINHN"
     gene            24455..24841
                     /locus_tag="IV356_001144"
     CDS             24455..24841
                     /locus_tag="IV356_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014846.1"
                     /translation="MLIAKRILASIVAIPCFLLSIIVIAVNIISIPILLVIQILKKVV
                     ILFITLVWIGFIGLFIYGLSSLGFSETISMFTVPTIGILILTLILSIFTFISDKIPNF
                     LGIVSSFFLSIPKFLWGAEETEEAEE"
     gene            24862..25929
                     /locus_tag="IV356_001145"
     CDS             24862..25929
                     /locus_tag="IV356_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014847.1"
                     /translation="MFSKKKYVQFIEQRDIELPDTPVEIYRGIYLLEQENDRLTDKHT
                     KGSTLILLTDKKGNELNRRLIQLPIEQGIETILTNLLIEPTSNKKQSSSKSQMILNDI
                     EEPKIKNKKKTVNYQTVFFLFTTNLAKKIYMALIIVLFLFFTSFFVLNNHSSTSTDSQ
                     SYHELLKKKDYEKIIKQYPEKENELVEKLYSEKNSKELKELAEKSDSQIALFYWDFLN
                     EHWQAVTTMKNVTPNETIQAMRGYAYLKQGKLDEAELINKEIDNQTLKDQIYQFKKQE
                     AYKALHEKDIEKAEKINKEINDSELSEDIKVAKSMVNLLQKYEKDRSDSKLSEDERKE
                     AENNYKLWSENLKQLGGNDNA"
     gene            25922..27502
                     /locus_tag="IV356_001146"
     CDS             25922..27502
                     /locus_tag="IV356_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014848.1"
                     /translation="MHNKKKFLVVGLFSAVLLGGAVTYGMYSQQPHNETEKTEQTTKS
                     ESSKHKSKKSAWEESVKGKEDKKEKNKHSTKKADDILAVIADTPLIKQQPNQNKNNLI
                     DRLAVALDDQTKKEADRQEKLIIKDKKSVDEPVLVDLSYKPQLEDTKPSNKENGKTEN
                     NKDENSELDKGNDTKPDNSLPDPLPVPEPNPLPDPTPSPDPNPIPTPDPDPDPEPDPT
                     PDPEPSIDEQINQSKEELNDSRKQADELNKQLTQVKDSLDNLQSIGASTEKNVDKAAL
                     QWQKVADLVNEYNQLTNEIKKLIEEDGTVLTINYDLYKETYEKLNQKVTEVKTAQKEA
                     NNTTNEINKNVEQATDTLNNLEETKKEYQNKQKDVSEVDSNVNSAINHAQSNEQVASA
                     VQDEINQAAQSNEQLNETNKTVGEQLNQVDPIESQTDIASAKEQTADINNQAEEQNNN
                     VDDMMNDFYNLPKPSDSEEPSVPENTDQNQDSTSQPQNIDNASVSQNKIENEQVSEKT
                     LPVTNQNSNQSEIEDIQK"
     gene            27521..28552
                     /locus_tag="IV356_001147"
     CDS             27521..28552
                     /locus_tag="IV356_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014849.1"
                     /translation="MSYKDSEAKKNNKTAELLSQAEEGIKEVLSSDKYKNFLRVMSKF
                     HNYSLNNTLLILMQNPNATHVAGYKTWKNSFNRQVNKGEKSIKIIGGRPYKRKVEEIK
                     NGQKEEKEVEGISFFPVSVFDVSQTSGEPLPQLMNELSGEVKNYPELYVALKQSTNFS
                     IEFADIQGGTKGYCSPLEKKIVLNNGMSQAQTIKTLIHEITHADLHAPEFDKNSSIKT
                     TKSTKEVEAESTAFVVCEHYGIDTKDYSFPYLAAWSSDKELKELKNSFEVILKQADNL
                     IQKIDKNLAELQKEVTKEKEEKQSTLSLSDQLEEFEDKAKSLNEQRDKEKLINKIRQP
                     KEQKDVSTL"
     gene            28634..28969
                     /locus_tag="IV356_001148"
     CDS             28634..28969
                     /locus_tag="IV356_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014850.1"
                     /translation="MKQYLDQWNIIEGALTEERINEIPDCLEKDHLFLIRRMLQKENF
                     EPNNFIVVEYPATGIYCCNHINNDQYFIVQEEKNKLVPYYTTCDMNEKGINNFPCTSI
                     KESMKLIEM"
     gene            28990..29259
                     /locus_tag="IV356_001149"
     CDS             28990..29259
                     /locus_tag="IV356_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014851.1"
                     /translation="MQTFTQHELEIISGHKQITGSNANKLNVIKSEVGEMLSMLKSDL
                     GKQYIEDDEQRHYTLKNYQSVYDKLEKMSEDEFKQIDLSGIEELE"
     gene            29494..29907
                     /locus_tag="IV356_001150"
     CDS             29494..29907
                     /locus_tag="IV356_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HAP9014852.1"
                     /translation="MEQKLAKTPENILKIANTYDDSERTFRKETRFSEREIFLLNYKM
                     SQANTRNFSQYARIMCLSGLMITTDFSDLKNLTTELGRIGNNINQLAHRANISNSVSK
                     EDFLELKTNYDQLTKLINEELLFRMRRARDNQRFI"
     gene            29907..32201
                     /locus_tag="IV356_001151"
     CDS             29907..32201
                     /locus_tag="IV356_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAP9014853.1"
                     /translation="MAVTKIHQIKTTLNKAIGYITNPEKTNNGMLVSSYNCQSQFAEV
                     EMQMTREYAREVKGDYRKVGGSEVLAHHLIQSFSPEDKVTPELAHELGRQLIDELTEG
                     KFEYVIATHIDQEHIHNHIIFNSVSFYDLKKFRSQPYRTANKIKEISNRICAEHDLSL
                     SPKKEKLKDSYKSYSNRRNNTSFRSEIRKRLIMCLNESTSWEEFEEKADHLGVNIDRK
                     GKHISYALLSEGQQRRTRGDKLDDLETFTESNISQKLSANQSYINQLKEAIEETFFSS
                     DNLEDFSFLLEQEHGITFQLNKQDQFVFHFNDVNDFKWNESLLPDSYQIKNLKDYFRE
                     SYEFTNDSSLNSIEERYREKEKSVIVQEDTPIQLQEFQIEKATKEGLLVSIEHEDLNG
                     LVFVPNNYVDVNEETGEYTIWINDKFDYTLTDKRTNEQTSFTVKGEGIIRGLEKMQGI
                     QPQEIKLSSKNILSMSNRGVSISIPELNIKRLFIPSEYVVIDEISKSCSILIGEKWNY
                     YAETLPENDDNSNKKLPYQKFTGRSLISSLKETPELLDVFLKPKFDQLHYQSRKRYTN
                     QLVEALNTIREEKIVSASQLEQRLNEIVEQKNQAKEKIAEIDGKIKNYNNVAKLLVTY
                     EKYLPIMNEIERATMLQKMKLEQKYKEEVRQFKFAEKKLLASDNLRPDLTKEKIISVA
                     KNQEKQRKRLIEGYKHYENKLNRLIDVQEILQELDRNGLFDLSGYRLIDREEKLTDKI
                     EKYEKEVEETQQKNAKEKRKEHEI"
     gene            32340..32552
                     /locus_tag="IV356_001152"
     CDS             32340..32552
                     /locus_tag="IV356_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014854.1"
                     /translation="MAVWQIQLKERGAYGLISLSDVLCRKEMPDLFSLDQIIAIIGAA
                     AVVITAVAKASDSILAWLKFKKEQKK"
     gene            32983..33606
                     /locus_tag="IV356_001153"
     CDS             32983..33606
                     /locus_tag="IV356_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP9014855.1"
                     /translation="MYLAYLRVSSDDQSLARQHKLIENWSVKNNIDEDDLKIFEEKVS
                     GKNIENRPELQELISFIRERDTIIIPSLDRLARNSKDTKDLLQLFRSKGASIEILDLP
                     SFNGVTDPALRDLLTNLVIEVFSYVAENERKKIKERQKQGIEIAKKNGRYTGKKIQYH
                     ANATGKNKLIYDEIVDGLKKKETISKIAKNAGVTRKTVYRVKRDLGM"
     gene            complement(33728..34687)
                     /locus_tag="IV356_001154"
     CDS             complement(33728..34687)
                     /locus_tag="IV356_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP9014856.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTKDDLSNLI"
     gene            34940..36187
                     /locus_tag="IV356_001155"
     CDS             34940..36187
                     /locus_tag="IV356_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HAP9014857.1"
                     /translation="MKNKLTLLICATILSTWAVPTQNAFAEETGNDTTQQTVTSNSSN
                     EEQTAIINGEQVKLEAPVKEGQSEAEATQAPKEELQQDQMSRFARSAVRTIPMYRMYN
                     PNSGEHFYTQDTGERDNLRRIGWNYEGIGWQAPTSGDPVYRLYNRYNGEHFYTLNAKE
                     RDNITKQGWTYEGIGWYSYKGANGIPVSRLYNKRVNWHHYTLDEHEKNVISKQGWNYE
                     GVGWYAVGNGQPSNDDYKLLGVKNYNQYALGAPSGCEGASLLQALQYKGKITNWSLTQ
                     FLNTIPKSPNGNPNNGFVGSPFVENSWTYSAIYPAPLTTWGQKYGNVQNISGSSMNTL
                     LNEVKNGNPVVAWVTINFQPIRWGNWSFGVAANNNHAVTLDGYNKGSNQVHVSDPISG
                     SYWMNRTTFENIYNARKYAVVVR"
     gene            36464..37789
                     /locus_tag="IV356_001156"
     CDS             36464..37789
                     /locus_tag="IV356_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAP9014858.1"
                     /translation="MMDYSKEPINDYFLIDMKSFYSSVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLYVVPPRMNLYIKRNMQVNNI
                     FRKYVADEDLLIYSIDESILKVTKSLNLFTTVGTRSQRREKLAQLIQQHIKKELGLIA
                     TVGVGDNPLLAKLALDNEAKHNDGFIAEWTYQNITEKVWNINEMTDFWGIGSRMKKRL
                     NQMGIMSIKDLANWNPYTIKSRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRTEIELVVKEMAEQVAIRIRQHHCKTGCVHLHIGTSILETRSGFSHQMKI
                     PITDNTRELQDYCLFLFNKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDDEK
                     LDKIIDKIRQKYGFTSIVHASSKLEGARSITRSTLVGGHAGGVGGLKND"
     gene            37782..38132
                     /locus_tag="IV356_001157"
     CDS             37782..38132
                     /locus_tag="IV356_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014859.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDAENKQRVNQNLAKKQMTTE
                     EISKVLNAAVIKNRSVCIQKEERNAEGYYPDDIIGKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQELKWSCLE"
BASE COUNT        14512 a         5601 c         6972 g        11256 t
ORIGIN      
        1 tattttgcac tgcttttata ctatttttta caattttttt atttgctgga ttcatgttgt
       61 ttatataaaa ttctacaatt ttatttaacg tttcatatat ttttttatct tcaattgtcg
      121 caatcgtgct gatcgcagtg tgagtatcta atggcattct tatagattta ggtaaatctt
      181 tagttgtgag tcgttttttg gattgttcta gaattttgcc tgaatcagtt gtgttattca
      241 aggcttctga attttctgga acaatatttt caggtcgttg tgttttattt tttcttttta
      301 tggcatttaa accaattgat tcattttttt cattagtcat ttttaaaagc tccttatcct
      361 aaaagattaa tacgttgtat tacttcgtca ctaacacttt cataaacttg ttgaactctc
      421 ttatcatgaa tgtcttttgg attatcggtt atgccagttc tatcatacct ttttaatctc
      481 tgcattgttt tgattttagt attgaatata ttcgattttc caaataatga ctctgcgtct
      541 tcaataatat cgaggtctaa atcattaccg ttttgaacta gtaccggtag caaacctaaa
      601 atatctattt ctgttccata atcattattt aattgaatta aatgttctat atatttttca
      661 gctcccttta acgagcgttc ctgtgtttgt agaattacaa taacatagtc acttgcaact
      721 aaagcagaat tagtaaattt atttaattgt gggggtacat ctatgataat aaaatcatag
      781 ttctctttaa tttcatttaa taaatttgag aaatgcgtat ctttagaata atcgtcgtca
      841 tataattccg ctaaataatc aatatacttt tctaaatcag taaatgatgg taatagatct
      901 aaattttctt tcactgagat tagtgaatta gaaattttat tattttgaat agaaacgaat
      961 aatgtttctt taaattcagg ttttattttg tatacattgg tcatagttgc aaataataat
     1021 tctgtagcat tagcttgcgg atcaagatca acaactaaga ctttgtaacc cttgttagat
     1081 aatgtataag ctgttaacac agcattagtt gttttaccaa caccaccttt aaaattccct
     1141 gtggttaata cttttgtcat ttgttaatac ctcctgttta taattttata cttttataaa
     1201 attattatac tgctatccaa ataaaatgta aacataaaaa ttttatactt ttataaaatt
     1261 ataaaagtat atatttataa gtactgatac aaagagtttt aaagcgtttc gttcaatctt
     1321 aaaataattc tattttatga acttatattt gtataaaatt ataaatttat aattttatac
     1381 aaagctaatc tgattaaaat gtttttataa aaatattgag attaatggtt ttattctgta
     1441 tactaaatgt aaatacagaa aagaccattg ctgattggat tggcgtcctg caatagtctt
     1501 tgtgtaagta attaaaagat ttaatttatt gtattatagc atattttaat tacttactcc
     1561 actacatgaa aataaaagga gtaatattat gtcagaattt aaatactaca agtcaaaaga
     1621 aatttatcgt gaaaaatact atcaaatgcc aaaagtattt tttactaacg aaaaatattt
     1681 aaatctatca aatgatgcga aaataaccta tatgcttttg aaagcacgct ttgattactc
     1741 agtacaaaac aagtgggtag attctgagga taatatttat tttatttaca ccattgaaga
     1801 attaatgaga ttactaaact gtcgagaagg taaaatttct aaaataaaaa aagaattaga
     1861 atcagcagga ctacttaagc aaaagaaagg acgtatcaaa aaagcaaacg gaaaaattga
     1921 aactacacca aaccttttgt atctcggtaa acctgaagtg acttcagagg acgtatttaa
     1981 aataaacgaa gaagagcgtc taatcccaaa tcctgtaaat gcgaaaatcg caaatacaga
     2041 aaaaaccgat gaaatcaagg atattcctgt aaatgcgaaa atcgcaaata cagaaaaaac
     2101 caatgatacc aacgattttt ctgtaactgc gaaaatcgca gacaatatat tatattctaa
     2161 taattcttta gacactaata gacacaatat agacactgac aaagatcagc tacaagatca
     2221 attattgcta gagaattttg ttgatataat gactgattcc agctttgata cctttatacc
     2281 aactaatgtt ttgaaattga ttaaaacttt ttcaaatagt tacagtgaag cacaacaaac
     2341 agtcaaaact atacacaatg caaagcataa agcccaagaa tcaaaaaaca caattattgt
     2401 ttacgaagaa attgagtatt ttggaattga cgcagataaa ggattatata tgactttact
     2461 gaaggcatat caaaaacaga aaacagagaa agttgataac ctacaaaacc taatttttat
     2521 ttacgtaaaa aactggtttg ctgagaaagc tattcctgct aaattagcac atgaacaaac
     2581 cacagaaact gactcattac ctgctgtaaa tctcgaaaat tggttagatt aaaaaaaacg
     2641 aacatatgtt tgcaatatgg acgatgagtg gtataatttt attgtgatat atattacatg
     2701 atcatttaac aaagaaaaaa ttagaataaa tcatgttatt tggtttctaa attttcatta
     2761 aaactttcat gagtgttctt tatttgataa cgatagtgtt tctaataaac aacgtgaaaa
     2821 gtgcgtaatg taagctttgt tatcaatgat tttagatgtt aaaataattc cagaagcgct
     2881 tcgcaactat gttagtgaag gtggtgtata tcaaaatata attgttttat gtcgttttac
     2941 aataattagt acttacacaa atttgtcaag tgaaaaataa aaaagcttgt aatgaatttg
     3001 aagatgtgct accgtaaatt tgtagaaacg taaattaaaa aaattattga ttagcaatcc
     3061 agattgctga tcattgagaa gccaagcaat aaatcaacca acaaaaaaga gcagaccgac
     3121 tagtgatctc gctgggtaag agcgccaact cttacttcag gtcatgaatc gctagccgtc
     3181 ctcaattcaa cgtcacacac acgctgaaga ggtaaactgc cacttttgtt gcagatttaa
     3241 ctgcaacagg catattctaa catatatttc ttaagaattt aactagttta tttgtgctac
     3301 ctaaattctt taaaagaaaa tttgtatttc tctggctact tttttgagta gacttagtgt
     3361 gcaattttct agatatattt gtttatactg tttgcagctg atttgtgact taagagggca
     3421 attacacttc atgtgtgatt gccctctttt tgtcgtgctt ggcttcccaa tgatcagcaa
     3481 ctgaagcaga aaggcggaga aaaacatgga gttaaaacct agaaacttaa aacaaattac
     3541 ttgcgaattt gtactgttta atcgacaaca cataaaattt tctaatcgaa cgatcaagcg
     3601 taaaattact gatttttcag gtaaagagat tattttatac gctaaaaaat tatcaagtga
     3661 acaggaatta gcttgctttt ttgatcaaat aaaagctgtc tatgttgacg gcaagatcgt
     3721 tgcttgtaga ggctgttcgg aacttccctt aattgtttca aatcatgtat tttcaaaaat
     3781 gaaagcacgt cagaagctat taagagagtc gaaaattcgt tatagagaaa tgcaaaaaga
     3841 ggaaacgaaa aaaagaaaga gtgtagcatg caaaaaatat aaacgaatca gtgcgtagct
     3901 actgttttga ctaatggtac ttgatttttt tgtttgttag ttttttctaa caaacaacct
     3961 aatagcaggg atttattgct atcgaaaaaa cggacaagta agcacacgga cacgaaacag
     4021 cgctaaatat ttatttaacg tttgctggca aggagtcaca tgacactaag cgatacacgt
     4081 aaacttactt tgatgttttg ggtgttcctt gacaactgaa aaattacagg actttctaag
     4141 ttaatcagcg tgtctaatag gggcttagga aggataaacc acctaaaaaa gtacggctgt
     4201 gttatcagat ggtacgttat tgatgggtag ggcacacaca gaaaaggtta tttgcgatga
     4261 tcagctatca cgaaaaacat aagatgacga ttaaaaccgt ccgctcgttt ttctagggag
     4321 caaaaacact tttcgagagt ttggggttgc tatcgctaga aaccctgcgt aaaaaaactg
     4381 taacatttat gagaaaacta ataaacaaaa gaatcaagtc tctaaaaaag aaggggacac
     4441 ctaatttaac tggagggtac acctatgagt actgagaaaa aaagaaaaaa gtatgcattt
     4501 tctgatgaaa ctatagaaaa attggattgg ctagtaaaag agcaccaaaa aagaagtaaa
     4561 aaacgtattt atccttgtga tacactttct gaattgatca ataatgaata tgtgataaga
     4621 aagagttttg gcaattcata agtaatagtt tacttcttta attccttaac aagtatataa
     4681 aggagctgag aaatttgaat cgtattcgct ttggtaaaag taataaaaac gagttctcaa
     4741 gtatttttaa ggtaaatgtg ggtatagctc tagtattttt tcctttggga atatggggag
     4801 gtatgagagt tcaatgcgaa caaagttact tcgataacac aattgacgaa gtgtattttg
     4861 aatatgattt agccactcat agaaattata atcctaaaga atctcatgaa gtatctttaa
     4921 gaagagttca atatctgact tgggatttat atccactttt aaaatatcca gaaagtgtaa
     4981 ctagcaaact tttttatatt gataaaagga ataacgaaaa agtagagaaa gcgtgggtta
     5041 ctcttctaaa actgcaaaaa attgctttag aagaaaaata aattaatttt tatgaggtgt
     5101 tggtatggaa tggttaaaaa atgaaaaaga gctttttcaa tttctaagtg atatgaaaag
     5161 gaagaaccaa gtagcaaact tggataatta tatcaaatgg atcaaagatc agtcagtgca
     5221 aataaaacaa gatagagagt ctagtaactt aaatatcaaa attgcagtaa cggataaaca
     5281 aaacaacatt ttaatttatt aaggagaata aaatgatcga agaaaaaaag aaagtattat
     5341 attctaataa acccgaattt aaaaaattgg ttatgcaata tgctaagaaa aatattggtc
     5401 gtagcattac ttacgatact tttattaaat ggttagataa gtatggatat gatttgtcac
     5461 aatatgatac ttgctggcaa gcagtattta aatcactctt acaaagaaac ttccaaatcg
     5521 acatagcgta tagaaaaaca aaagaatgtc agcttattac agtatttcaa ttaaacaaaa
     5581 gttaacgatt atgatctcaa aataccattt tatgattttg atacaataat cacaatatta
     5641 tatagtaaaa ttttttagat gagggtacaa aaatagagag ctaaatgtct ctctatttat
     5701 aatttgtatg ctagatagtg attatctttt ttagctaagc caaagacttc accaactttt
     5761 agatttttct ttgagtaagt caggcttggt atttcaaaca agttgttttt cttatcagtc
     5821 acaattaagg gaagctgtat ttctttgttg ttctctgtag ttagaacagc tatattctta
     5881 ttttgaaaca aaacagtagt aatttgagtc ttccctagaa tttctatatc tgaaccttgt
     5941 aattgtttta attcatttaa ataaggatag acagtttctg tttttattgt actttctgtg
     6001 gttgctgtac tcgctgttat atgcttattg tttttgggcg agttggtaaa aaagaaaaat
     6061 gcagcaacac aaagtaagaa aattgttgct aatgtaatga tgtgtgattt tttcatagca
     6121 tatctccatt aatatcaatt tataaaaagc agaaactgta attatggttt ctgctttttc
     6181 tcttttaact gtttagcata ggcttcaata tcgcttttga gatagagacg aactactgaa
     6241 ggcccttttc cttccttgct ctcataaaat ggtttgatta catttgtgcg aacagattgc
     6301 tgaaatcctt taggagattg ttcagtaatc ttgattgctt cttgtttagt aactaaatta
     6361 gtttcaatcc attcttttag ttcttctata ttagtgatgt tcatattaat cccacctttc
     6421 tgtggatttg tttgtctata gaaatattat aaatgaaaaa aagtaaaaaa tctaatataa
     6481 aatggttgca atactattcc attactggta tagtattaat ataataaaaa ttaagaagaa
     6541 agaaggaata aaatatgaaa ttattgaaag tgttagctgt cggagtaaca gtaggaggaa
     6601 ttgcgttagc aatcaatcag gagaaagtaa gcgcagcaga gtggacacca agaacagtcc
     6661 aacaaatttc agcggatatt gcaaaaacaa atggaaaaga atataccatt gtttatggtg
     6721 atacgttgag cggaattgca caagctacta atcaaacagt tcaatcatta gctgaaaaaa
     6781 actctattgc gaatgtagat ttaatttatg caggtaacaa gttaattttt gacgggaatg
     6841 tagttactgt tcaaaatcct caaggagaaa caattgctca aactgttgtt caagattcag
     6901 ataagattga cccaactaaa ccagtaggac aaccagtaca agatacaaca agtaatgcaa
     6961 ctaactcagc tgaccaatct gttgcaccta ctacaccagc tggagatagc ggagcaaaca
     7021 ctccagaaca accagttcaa ccttcaacac cttctgacaa tgggaatcaa ggtggaacgg
     7081 taactccaaa tcctgatcaa aatcaaggtg gaaataacaa ccaagataat caaggaaatc
     7141 aaggcggcga cactggaaat aatggaaacc aagacaatca aggaaacaat aatggaaata
     7201 acaacaacgg aaacaacaat ggcggtaatg aaggtggcga tgtaacacca ccgcaaccag
     7261 ttgaaaaatg gacagtttgg tattctgctt cagatgaagc taacgctgct cacaatattg
     7321 aaaaaggaac aaaagtattt gatacagaag ctgaagcaac agcatggatt gatcaatatg
     7381 cagatggctt gttagcacaa ggtattactt caaattctta tggcgtatct tcatttttag
     7441 ttcaagaata ataaaatctg tttaccaaga cacttaagaa aattcttagg tgtctttttt
     7501 ttaccctttt ttcaaattgc tattgaaggg tttattttct taaggggggg tgattccaat
     7561 ctaaaattta atgtcagtcg gtggagcgag cctttggggg gcgctctttt tttattgtac
     7621 ttatatatat tgattgaaga gagggagatt atagtgagaa taaaaaacaa gagaaataag
     7681 tggaaagttc ccaagtatct attgatgatt ttaggggcat tggcaatgtt tttaggattt
     7741 ggacttagtt cgcaaagcgt aaatgccgat aatattacga tgaagccggg agaaaaaggc
     7801 gatatctatt atgatgcaag taatgtttat actatgcatg gtacgaagca tgggcaacca
     7861 tggagcgacg caacagctgc aatggcagtt tctcctaaca atggggctac ggatagaatt
     7921 gtattttgta ttcaacccgg tgtgcctttt attaatacaa ataatccaga ttatgaagca
     7981 gttgctgtaa ctgacattcc taaagacgca caaattgctt ctgtcatttg gaatacgttt
     8041 tatgcttttg ggactaactt taccaatgaa gatcgaattg tcacacaagc tgtcatttgg
     8101 gaattattac cacaatatgg aatcaaagtt gactctatca gtggtattcc tgattttcag
     8161 gctaaaaagc aaaaacttta tgatggaatc aaagaatata aacgtttgcc agaatttaac
     8221 aacaagacga ttgatctaac atttggcgaa actaaaaaat taacttcttc tgtagattta
     8281 aattcttttg aaactcaagt ttctaatagt gcaaaagtta actggaacat tgcagctgat
     8341 ggtaaatcag tcgatgtaac tcctactgat cctaatgtga caggtggaag catttctttt
     8401 aaacgttcat acatggaagg aacaccaatc gcattagaaa aaacaggctc acaaacagtc
     8461 tacttaccaa gtgtaaaaga ccctaataac tacagcgtga atttccgtat tcaaacagtt
     8521 ggagatatta caattaaaaa agtagataaa gaaactggcg aagttgttcc taatacgcaa
     8581 tttaaagtag agtttagtgg taaaggagcg ccttcagcac aaactgttac tactgataaa
     8641 aatggtttag caacgatcaa aggaattaat catggtgtgc atgtcaaagc aacagaaatt
     8701 gctgtaccag ctccttatgt tttaggatca gctattggcg attctgacgt agtagaaggc
     8761 gatgttgtcg caggacaaac agttacttta acacaacgta accaaaaagc taaaggacaa
     8821 atcctgattg aaaaatctgg tgtagaaaca ggcaaagata tgtggaatgc taactataca
     8881 ttagcaggaa atgtatttga aattcatgag ggaaatgaga cagggacagt tgttcgcact
     8941 attacaacgg acgacaaagg tcatgcagaa acaggaaaag atttgccatt aggtacttat
     9001 gtaattactg aaaaaacagc ttctaatggg tttgctaaca cattcaaacc agtaacagtg
     9061 aaaatcgaat atgcaaacca aacaacagca gtaatcgtaa aaggcgctga aggaacgaac
     9121 caagaagtcg ttggttcaac attgttaacg aaagaagacg ctgaaacagg caaagaaaca
     9181 caaggacgtg ctacttttga tggggcgcag tacggtttat tccataaaga cggtactcct
     9241 gtgaaatggt ctgaaaactt caaaccaaca acttctaaag gaaacaaatt agaaggcgac
     9301 gaagtgaaat ttgaattatc tgacgaagaa caacaagcaa gtgttgaaca cttagcatta
     9361 ggtgactact actggcaaga acttgttgct ccagaaggat accaaattga taatacgaaa
     9421 cgtgaatttt ctattactta caaagatcaa gagacaaaag taatcgaaac tcaaagcact
     9481 tcacaagaaa atgtaatcaa atttagtctt gatggcttta aatatgttga ttcaaaatca
     9541 ggcgatacta agactggtta caatggaatt gacttcacgt taactcctat tgatccaaca
     9601 aaaggcgaac aacgtaaagt aacaactgaa acagatgaaa acggctatga tggatactgg
     9661 gcattcaatg aagtccctta tggcgactac aaaatgtcag aagtaaaagc tccagaaggc
     9721 tacaaaacaa ttaaagattt aatcattaac agcaaatttg atgctgaaaa acgtgaatac
     9781 acatttacca ttactgaaga cggacaaaaa gaaccaatta aaacattgac tgtaccagaa
     9841 gctaaaatca atgaaggttc aaatgtgatt catttaagca aattattctt aactaataaa
     9901 gttaaagaaa tgccaactat ccgcacaaaa gctactgttg acggagaaaa aacatttaca
     9961 ccttcaaaag aaacaccaat gcaagacgtt gctacaatta ctaacgttga aaaaggtgtc
    10021 gaatatacaa acaaaatcaa actttggaga attgttaacg acgactatga caatgctaaa
    10081 gttgtttggg aaggttctca tgattttgta gctgaaggcg ataaagtaga agacgttatt
    10141 aaacaaatgg tagatacttc aaaagatgac aacactgttt cttatgtatt tacagaagaa
    10201 ttattcatta aagatggagc aaaagttgca gaacacaacg acttaacgaa taaagaacaa
    10261 acgattcgtc cagtcgagcc tgaattgcca actattgaaa cattattcgt aacaaaagat
    10321 ggtggcaaaa catttgatcc aacgaaagat caaacattaa ttgatgaagt aaaagcaact
    10381 gtacctaaag aagatatcgg tcaaacattc tactatgtaa cacaattcca taaaattgat
    10441 aaaaatggaa aagttactgt tgtaggtacg gacgaatcag aacacaaagc aggcgaaatg
    10501 acttatgagt tcaaagcggt ttataactac aaagcgaata ctttgaaaga cggcgaaaaa
    10561 ttagttgcga ctcatattgc ttatacagac aaagaacaca aaaacgaata tgccaaacac
    10621 tttgatttga aaaatgaaaa acaaacacta acggcaaaaa caccagttac gccagcaact
    10681 ccaacaacac cacaaaaatc aattccacaa acttctggat cattggttaa tattggaagc
    10741 ttaatcgttc taggaattgc tgctgttgca ggtgcagcat tgtatgttac aactaagaaa
    10801 aaagtaaata aaaacgaaaa ataagaatga aggggaagca ctttgaaaaa ggtgcttttc
    10861 ctattttagt tattgttttt agggaaagga gagatcaata tagtaaagaa aatcattaaa
    10921 gccttaccgt tattgtggct acttagtagc ctgattttag caatctgtgg attttatggt
    10981 tataccgttc ttcttcgtcc cgaaaataca atcaaacaag cacagcaaat cactcaccct
    11041 atacagtcag agaaagagat caaggagata caacaaacga caatagggaa agcaacatac
    11101 aatgaaaatc agatccaacc tgttacacct acagactatg cggaagcaca gctgagttat
    11161 gaggctcttg ttaaccagtg gggaatcggt tctctctata ttccgtcttc tggtatatac
    11221 tccaagattc ttgcaggaat gagcaatgac aatttaatgg ttggcttagg aacctattat
    11281 ccaaaccagt tacttggaaa agggaactac gttttgatgg cacataattt agttcaaggt
    11341 gggggagttc ttcgtaattt accacaatct agcgtaggat caacaattta tgcgactgat
    11401 tttagcaaga tttatgaata tgagatcact acaaataaaa ttgttaacca atcagagggt
    11461 aagttattgg atatcccaca agaaggtgat tcgcctttaa tgactatttt tagatgtgag
    11521 ggaggattac acacagctaa tcgtgcatta attcaagcta ggtatgttcg atcttactca
    11581 gctgaaaatg gttcacatga tattaaacaa gctttaggat tagaaacaac gagaaataag
    11641 acagtcaata aacaacgtct aaatgaccaa caggcgactt caactaatag aactgaagca
    11701 gcaaaggaaa gtattactcc cgataaggat actaaaaagg caaagcaaac aaataaaata
    11761 gaatggcgct tcacagaaaa gaaagctatt tattctaact tccaagtgtt ttctatccta
    11821 gtatttcaat tagctaatgc ttatcctatt ctgattgggt tagtttttct tgttggtctc
    11881 tcaagttgta ttctattgaa cagaatataa tgagtgacaa aacttatata tatttttata
    11941 aaaaattcat aaaataaagt tatcttagat gtaacacagg aaaggaaaga gaaaaagtga
    12001 aaaaaaagca tatttcaaaa gtagcttccg ctgttcttct ttctcaaatg ctattgacaa
    12061 caccgttaca ggtattggca gatgaacagc tttcaacgac aactagtcaa tctagcacga
    12121 tgaataatca gtctgaagaa tctacttcaa gtagtgatga acaaacagga acgtctacta
    12181 cgcaaacagc gactgattcc acagaaagta gtgcagatca aagtacaacc gaggatacaa
    12241 caactagctc gacagatacg acgtctacaa cagaatcgtc tgaaaagcct acagaagaca
    12301 gtacgacaga ttcaacaagt acaacagaat ccagtagtga gtctaaacca gatgaaacca
    12361 aacctagcga aacaaagccg agtgaatcga aaccagaaaa gccgaacact ggcagttcta
    12421 cgaatgaatc acagactcag ccaacaactg aaccttcaaa caatcagcaa gcaccgtctg
    12481 ttgctccaaa caatcaagca aaggcaacaa acgaagggca gcaagctaaa ccagcagaaa
    12541 gcgagtcaaa accgtatcac caaacgccaa ctgcacctat tcaagaatta gttccttcaa
    12601 gcaaagaaac ggctgaagga aatattcatt ttgaaaaaga tgagtccgta gaaagctttg
    12661 tccgaaaaat cggcgagcct gctcgcaaag taggacagga gaacgactta tacgcttctg
    12721 tcatgattgc gcaagccatt ttggaatcag ctagcggtca aagtcagtta gcccaagcgc
    12781 caaattataa cttgttcgga atcaaaggaa cacataacgg aaaaggtgtt tcttttgcta
    12841 cacaagagga tttaggtgac ggcactcttt acaccacaca agctactttt agacagtatg
    12901 aaaactatga ggatagcttg aatgactatg cacagctgct taaagaaggt ctgactggta
    12961 atagtcaatt ttatagtggt gtatggaaaa caaatgcaaa aacttatcaa gaagcaacca
    13021 aattcttaaa tggaagatat gcaactgata cgaaatacga tcaaaaatta aatggtttga
    13081 tcgagaccta tcatttaacg gactacgaca aggaagtcgc aggaccacaa ttaagtaaag
    13141 aaggatatat tgtaccagtg aaaaactata cgatttctag tccttttggt actcgtgggg
    13201 gagaatttca tagaggatta gatttggcag cagcacaagg tgagccaatc tatgccagca
    13261 aagcaggaac ggtcgttaaa gcagagtttc acccttcatg ggggaattat gtagctattg
    13321 agcatgaaga cggtacaacg gctttatatg cccaccaaca agaatatcaa gtcaaagttg
    13381 gcgacaaagt aaaacaaggt cagatcattg gctatgttgg ctcgacagga aatagcacag
    13441 gtagccattt acattttgaa ttatgtttag atcaaagttt aagccaatca caattagttg
    13501 atccagaaac agtcttattt taaaaataag gctgtttttt ttattcaatt tttaaggagg
    13561 tattgtctat gttgctattt ataagtggtt tatttttagg cggatttatt ggtgtggcat
    13621 tgatgtcatt agtagcaatc gatcgttatg aagatatgat tgatgaaaga agataattaa
    13681 gaaagaggga gtacaaattt tatgacgaat agaaatgaag gaatcactat ctacttgact
    13741 attggtaaag aagttaagtt aaattttgat tcagagaata acttatcaag tattcgtcta
    13801 tccattaata aagttgcaga acttttcgga aataaagtag tcaatgaaga aagtatattt
    13861 tatgtttcaa cagtagcctt agtgacaaaa agtaactata agacttttat ttcagtagta
    13921 ggtggaaagc aagttattag tggagacgca gtttatgagg aagtaatgat tgatcaagaa
    13981 agaactagca ataaaagagg aaacaaaaat gtatacgagc aaggatactt tgaatttttc
    14041 gtgtcagaag aagacaaaat tcctaaagag aaactaattt tgccttacaa cgtaaaaaaa
    14101 cgtaggtaaa aagcttatgt gaggatatat ctatgaatat aacagtaaaa gaattaggcg
    14161 aacctataga actcgaagat tatttagaag aatataaatt ccaagtcata tttttattaa
    14221 aaaatatgac ttttattgat cgtaaagata atcgggtaag acaacttttt aatatggaac
    14281 tgattcgagc ggaaactaag tggtattctt tttaccaaaa aaatcaccgt ccacctgatt
    14341 ataactttct acaagaagag attacgtcat ttggtgtcaa tcgtttgccg atgtttgata
    14401 gaagaaatga gggacgtgtg aatgacgaat taagcgtaga caactttgtt cactatcata
    14461 tacaacaatt aaagcttgaa aaaatactgt ccccagcttt ttttgaaaaa aatgatttac
    14521 gattcatgga gagatacgca aaaaataaag cgaaagctta cttcaatgag cgtgatcaat
    14581 atataaaagg ctatgaaagt tttagaatat ctcgaaataa aatcatgcaa cgagcaggat
    14641 atgaacaact taaatatgaa tttgtttctg ataatatggt tcaaggttat tttaaagagg
    14701 aggttgctaa aatggcagca aatgacgaac gagtggcgga atttgttttt gatgaaggta
    14761 aaagcttaat gcgaaactta acacagaaaa tgagcagggg aggggtatca attgttaatg
    14821 gctcaacaaa agcagtaact aatcaaatta aaaagcagag aactacagga aaacagcgct
    14881 ataatcaact aaaaaagcat ggagcgttag aacatattga tgtttcaaag actgatttaa
    14941 agccacttgc aaatgaacta aagaaataca aggtagattt tgcagtaaaa agaaacaaag
    15001 agacgggtaa aatacatgtt ttctttaaag ctcaagatag agatacactc aatttagcat
    15061 tagaaaatgt gctacaaaaa tttactaatg aaaaagaaca gaatagagaa caacagcagg
    15121 agaaacctaa taaagatatt gaaaaatctt ctgtcgatga caaggataaa gataaatcgt
    15181 taactaaaaa acttgataaa ttagaggata aagcgcaaga aataaatcaa caaagagaac
    15241 aactaaaaga gaacacgaaa aataaaacta aggggcaaga acgatgaaca tcaccaaaaa
    15301 agatcttatt tttggtgtcg cacttgctgc ttttttcttt tatttaggta ctttattttt
    15361 tatggtttat ttctcgattc ctcaaaatac agattcttca tggataaatg tagtaaatga
    15421 agcatttgat aagttcttag aacctaagac atttaccatt tctccattta ctttttcaaa
    15481 aattgctatg aaaggtgggg cgataattgc ggttattgtt ttactgattg atttatatat
    15541 tataagtggc aagaaaaatt taagaatggg cgaagaacat gggagtgcca aatggggtac
    15601 ttctaaagac attgctcctt atgtagataa aaaatttaaa aataatcttt tatttacaaa
    15661 tacagaaaga ataacgatcg aaactaagtt aaaaaagaat aaggaatatg aacgtaataa
    15721 taacgttgta gttgtaggtg gagctggttc aggtaaaact agattttatg tattgcccaa
    15781 tttattacaa atgcactcaa gctatgttat taatgactcc aaaggtggaa tcttgagtga
    15841 tacagctgcc attatgcaac aaaatgggta tcggataaaa gtatttaatc tgaataccat
    15901 gaaaaattct gatggttata atcccttcca ttatattaga agaacagaag gagattgtga
    15961 aattgatata ttgaaagtag ttaacaatct aatgaagaat acttcagacc ctaacaaaaa
    16021 gggtggagat tcattttggg acgatgcaca aagatctttt ttggcagcta ttttccattt
    16081 gttgattttg aaaggaaaac ctgaagaaca aaatttaggg atagtagcag acttagtaag
    16141 acgcgcaaga gtaaaagaag atgatgaaga atatatttct tcgattgatt tagtatttca
    16201 agaattagag caagaacagc ctagttgttt tgcagcaaaa cagtatcaga attttaagat
    16261 ggcagcagga aagacggcta agagtatttt aattagttta ggtgttcgtt tgtctccttt
    16321 tgacgttcca gatatcagaa aattaacgtc aacggacacc ttagaattag atacaatagg
    16381 agatcgtaaa actgtacttt atattatttt gccagatact catactacta tgaactttct
    16441 agcaagtatg atttaccaac aactttttga tacgttagtt tataaagcag ataatgttta
    16501 taatggatcg ttaccaattc ctgtaaggtg tttgttagac gagtttgcta atactggaca
    16561 aattccagat tttgaaaatg ttattgcaac aacacgtagt agaggaattt cagttgatgt
    16621 tatcttgcaa aatttaacac agattagtaa aaagctttat aaagacagtt gggaaacaat
    16681 cataggaaac tgtgattctt ttttgtattt aggaggaaac gagcaaagta ctcataagta
    16741 tatttcaact caattaggaa aagaaacaat tgatgtagta acttataacg aatcaagggg
    16801 aactacggga agttttacta aaaactctca aaagcaggga agaaacctac ttgatccaaa
    16861 tgaagtgcgt gagattaaag gcggaaaatg tatttatatg ttacgtggca caaagccttt
    16921 tttatctgat cgttttaagt tggaacgcca ccctttattt aaaaagttaa aagagacacc
    16981 ttcaggttat atgtatcaat caccgttgga tcaagaagaa tttattgcaa ataatgatcc
    17041 aattgatttt gaattatcaa aaaatgtcga tatgaaggag tttttgaaac atacggaaat
    17101 cgaaacttat gattttgaag acgaagaaat tgaaacaata aatttagatg aattataaaa
    17161 ggagagaata attaatggga acatttaacg ctattataga tattttgtcc aaatacgcta
    17221 ttgtaggcgg aggcttatat gcagtatggg gtgcagttgt tttaggtggt gcattaaaag
    17281 accacaatgg tccacaaatg caatcaggca tttggcaaat cgttggtgga gctttaattg
    17341 tagcagcagc ggcgttattt aagacaattg tttagaggat agtctttaat gaaaagggga
    17401 tgaatgatgg acggattttt aacatggtgt gtcgaatcta ttttagaagt aatctccttt
    17461 agtagtaaga caagccactt aactagcaac ttagaaaact ttagtcctca gttatacaaa
    17521 tattcaacaa ctattcttga ttctgtctca aagccaatag ctttcagcat attggctttg
    17581 ttttttgctt tagaattaca aagaatttct aatcgtgtgg agactaatgg tggaggtcaa
    17641 actggttttg aaatgatttt taaatcctta gtgcgactag gtctatgtaa actagcaatg
    17701 gatcaagtat ctttaattat gcgagcgatt atggatatta caggatatat gactgataag
    17761 attaatcatt taggtatggg aaacaaggaa gtaagcgata tgctggacgc aaaaaaaata
    17821 ttagctccca ttttaaaaga aggactaatg tttaaagtag gtgtatcgac tgttttaatt
    17881 atcgcattac taattactat tggttcgata gtaatcgtac aggtagttgt aaatatgcgt
    17941 tttattgaac tatacgcatt cttagctatg tctccaattc caattgcgac atttcctaat
    18001 gatgaatggt cgagtatagg taaaaacttt ctaaaatcat ttacagcaac agcgttacag
    18061 ggaactttaa tatttatggt tatgcagttt tatccatatc tcttaagttc ggctttcagt
    18121 gatataacaa atagtggttc agcaagtgaa acattcttaa tgacactgat tgggataatt
    18181 ggtaatagtg tattactaat tttcgcagta atggcgactg gaagatggtc taaatccatt
    18241 acaaatgcaa tgtaggaagg tcttttcaat gaaaaaatct cgttgtaaca gcactctaat
    18301 tcttggagtg ctatttgttt ttttgcaaat actatccata ttattaacaa cttatgatat
    18361 ttcaaatcca ttaacactaa gtatacttta tgtatttttt attgtttctc ttgtttttac
    18421 actcataatg atcgtaatta ttacaaaaga gatgttgcga gattttaaga aattaatatc
    18481 tgatattttt tcacagaaga aagaaaagta ggtgtttgag tggcaattag agtaaaagta
    18541 ccaaaagaaa ttaaggatta tcaagaaaaa ttaatgggag gaatgagcgt taggcagtta
    18601 gtattttttg tattggcagt attaatctca gtaggagtaa cagcatattg tgtattggta
    18661 ttgcatatgt cggttgacgc agccggttat atagttatcc cactattgat acctattgta
    18721 gcatttggct ggataagaaa agaaggtatg cctttagaaa aatatggcaa gattattcta
    18781 aattattact cgaaaactgg aataagaata tatcagacta aagaaaggag caatctaaat
    18841 gattttagaa aaaaacgatt ccaaaaagtc aaagaaacaa ccaaaaaata agcaagcaaa
    18901 aaaagtatta aaaatcttag caaagcagaa aaaacagcgt ggaaaaaatc aacgtagaga
    18961 cgctccacct ttatctagcc aacgatcatt aacatataaa gcaatgtatg agaatggagt
    19021 gtgtgagctt aaagaagggc tttattctcg tacattcaaa ttttcagata tcaattatgc
    19081 aattgcagat caatctgagc aagaattaac ttttagctcc tattgtgagt tactaaatag
    19141 ttgtgattct gatacttctt tgcaaatttc gattattaat agaagtaaag acaagaaaca
    19201 atttgaaaaa gacttatctt acgaattagt tgatgatgga ctagatgtat atcgaaaaga
    19261 aatgaatcat atgatatcta ataagattaa atatgggaat agtagtttac aaaaagaaaa
    19321 atatattact tttaatcaaa gagcaaaaac tttagaacaa gctataccag ctttaaatag
    19381 acttcaaggc gatttagaag atcaatttag cgaaatgggg tgtgaagtag aagaactgtc
    19441 aggaattgag cgtctaaggg ttgtcaatga tattctacgt cccaataaaa aacttcattt
    19501 tgaatatgag gatttacttt tcagtggctt aactacacat tcagcaattg cgccagatag
    19561 ttttgatttt aaatatcgta aggatcgttt caagatgggg gattattacg gtcaagtttt
    19621 gtatcttcgt aattatcctg ctgaactttc ggataaatta attactaata tcacagatat
    19681 ccctactaat ttacagatta ctttgcatat tgagccttta gatcaacaaa agggattaga
    19741 tttagtaaaa acaaaattat catttatgga gcaacaaaag attgatgaac agaaaaaagc
    19801 ggctagaagt aattatgatc ctaacttgat accaatggaa ttaagaagaa gtatggacga
    19861 agcacaagaa ttgttggatc aaatgcaagg agacaatgaa aagctctttt cttttacttt
    19921 tttagtgatg gcggttgata aagatgaaag aaagcttgat gacacaattg agcaaatttt
    19981 aactgcaggt cggaaaaatg actgcgagtt tgcaaagtta aattatcttc aagaagaagg
    20041 tctaaactct acgcttttat ggggaaacaa ttttgtccct atacatcgaa cattaacaac
    20101 tgctagtact gctgtattta ttccttttac tgcacaagaa cttatgcagc caaatgggaa
    20161 atactacggt ttaaactcag taacaaaaaa cttagtgacg ttagatagga gaaaactaaa
    20221 agctcctaat ggttttattt taggtactcc gggtagtgga aaatcttttg ctactaaaaa
    20281 agaaatgaca gctgttttac tgagtgatcc cgatgctgaa gtaatagtaa ttgatcctga
    20341 aagagaatat acacctttag cagaagcttt aaatggagag gttattcaga tatccgcagg
    20401 atcaaaaaat catgtgaatc cgatggaaat taataatgac tatgcagatg atgatgatcc
    20461 agtcatttta aagactgact ttgtgttatc tctttgcgaa atgttggtag gggggaatat
    20521 tggtcttagt ccgactcaaa aaactttaat tgatcgttca tgccgatttg cctacaagaa
    20581 atattttgaa aatgggtctg gaatgcctac tttaaaagat ttttctaata ttcttaagga
    20641 tcagcctgaa gatgaagcaa gacaattagc agtagagctt gaactttata ctgaaggatc
    20701 attatcagta ttttcccacc aaaccaatgt tgatacgagc aaacgtttta tcgtatttga
    20761 tgtaaaagat ttaggaaaac aattgcgatc gatgggcatg ttgattattc tagatcaaat
    20821 ttggaatcgt atcacaagta atcgaaatgc aggacgtcgg acatgggtat atattgacga
    20881 aattcagctt cttttttcaa atgaatacgc agagaattac ttttttgaat tatggtcaag
    20941 agcaagaaaa tggggagcaa ttcctacagg tatcacacag aatgtatcta cgctcctatc
    21001 ttcattaaat gcagaacgta tgctatcaaa tagtgatttt gttctaatgt taaatcaatc
    21061 ccaacgtgat cgagaaagac taggcgaatt gttacacatt tctagccgtc agaaaaaata
    21121 tattacgaat gccaaagaag gtgcaggatt gatgtatgcg ggcgattcta tgattccact
    21181 ttatgatgag tttccaaaag atactaactt atataaagtg atgtcaacta agattgagga
    21241 cgtgtataag tatcaaaatg agcaaagaga acaaggtact acagtatgaa cacagatttt
    21301 cgagaacgga ttatccgaaa acaaaagaca gcaaaaaagt ttgtagtaaa tcgagataat
    21361 aatcagttca agaaaaaaat tgtatctact gactatacaa aacgagctaa gaaagctaat
    21421 catagtggaa aaataaaaag tagtcggggc acttcctatt taataaaaaa agattcagca
    21481 aaaaatgtag tcaaagatgt taactctaaa gcacaaaaaa atggtgttga acaggggaat
    21541 gcaactgctg aattagaaac gagtaaaaca ataggacgtg ggataaaaaa tagcactaag
    21601 gcaacaaaaa cagtggctaa aactacaact aaagttacta aaaaaagtaa agaattgatt
    21661 caaacaaagg cttcaaaaaa agaagtttta actgttgtta aaaaaggaag taaaaaaggt
    21721 ctcgtaaaca caagcaaagc tgcaaaagat acagtaataa atgaaatcca agagtttaga
    21781 ggtgattcag aatctcaagg gattaatgaa gcgattcaat taaaagattt cattgataca
    21841 ggtatcagtg gtgctaaaaa aacaaaaaaa gcagcaaata ctgctaaaaa aagtagtaaa
    21901 gcactaacaa aatttggtaa atcaagttac aaatatacac aaagaattgc tgaaataggc
    21961 atacgtagag ttcaacaagt tctatcaaaa gaagtagcaa aagcactcat tgctaaatta
    22021 gcgattccac taactttagc agtgcttata ttatcaattg ttacggctgt aatttcaact
    22081 gttaacattt ttaatttcgg agcaggcgac tgtgatacta gtgccaacta tgacaatata
    22141 actaccaaag atatagagtc aaatgctaaa agtatttact caattattcg taaagaaata
    22201 cctgagtcca cccctcaagg gatttctgga gcattaggag ctatgcaatt tgaatctcaa
    22261 ttgaatccaa gtgcagttaa tccaagctca ggtgcgacag gaattgccca gtggttaggt
    22321 tctcgtttaa cctctttaaa agaatttgca cacaaaaaag gaaagaagga aacagattta
    22381 ggtgttcaag tagaatttct gttatctgaa ttaaatagtt catattatca atctagcaaa
    22441 aaaatattag caatgacaga tgttcatgaa gcatgcaaag agtgggtcat gaagtttgaa
    22501 ggattatctc aagactctag ccaatggtat ttggatcaaa gaaactctta tgctgatcat
    22561 tggtacgcaa ctttagggac gagtgatcca attgctgaag gtactattag taatggtgca
    22621 gatagcgaat taaatacgct tacttgtgat ttagaatctg atggtggcga tattatggaa
    22681 attgctaaga gttggctagg ttggtttcac tatgatcaga tacaccctgc tcctgattta
    22741 ggaacagatt taaaaaatcc taataaaaat ggaagaactg attgctctgg ttttgtttgg
    22801 ctagttttaa ataaagctgg gtataaagta cctgcaaata tgcaatggtt tactggatca
    22861 atggcaagtg acgctagagg atcacaccaa tatttgaagc aaatttcaga gacagaagca
    22921 aaagcaggcg atattgttat tgttaatcaa ggtgctggag caggtagtaa tggacacaca
    22981 ggaattttga ctgaaaagtg gagaggtaaa gataccaaaa tcattcaaga aggtggaaat
    23041 ggcgatagtg taaatattga agcttttggt acgtccttta tgagcttatt agatggtggc
    23101 gatgttgtat tagcacgtcc tataaaaaaa taattagagg ggaggaagta ctttgctcaa
    23161 cagaaaatca gctactataa ctatatttgt attgatcgta tcagtatttt ctttatccat
    23221 tggattaaat attaagcaag agttaactgt aaaaactgca aattctaaaa tagctgcttt
    23281 agaaaagaaa aacgatattt taaaaagaga aacgaaagac caaaagagcc gaattagtaa
    23341 acttgaagat gaaaataata aaatgattga aacacaaata gtcaataaag atggtgatgt
    23401 ctacaaagaa tttacaaaca ttgctactaa atactttaag tcaagattta attatgatcc
    23461 caaaacatac aaagaaagta aggaaaacgt aagagatttg atttctgaag agttgtataa
    23521 gaaattttcg gagaatcagc taacttatgg agattctaat aatgtgagtt ctcgattaga
    23581 taatttaaag atatatagtg gttcattaat taaccaaaaa actattactg gtcttttgat
    23641 tgttgactat gaaagtaaat taggagaaac tgactggttt aaaaattcag aaatctatac
    23701 tgttcagtat gatattcatg cgaagaaatt gactaaaata caaagcttgg ggtcagtttt
    23761 aaggggagat atgattgaat aaaaaaattt tttctatttg tgtcttaatt tttactgtgt
    23821 ctatcatatt tttagcagat cattcttata tcaaatatat agaagcacaa aatgatccag
    23881 tctatttaga tgaatcaaat caagagaaaa tagttttcta cagaaacgat tgtagagact
    23941 gtgaaaagat catgccttac ctgatacgtc acaatttttt ataccatgac ttaacttttg
    24001 ttaacatgaa taacaaagaa aataaacgtt atattaagga gtatggtttg acttccgttc
    24061 ctacaatcat ttcccttaag cagcgttatg taggtacaga tataagtaaa ataaaaacat
    24121 tagttatgtc aaaaggagat gatttctgat ggcaagaaag agcttaacag aacgtattca
    24181 gcagaagaaa gaagaagcaa caaagcttga aaagaggatt caagaagatc aatataagct
    24241 agaaaaacta acaaagcaaa ttagagattt agaagcagaa caggttttag cgattcttga
    24301 taaccataag cttagtgtga aagatttgaa taaaatacta agtaaacagc ctgataacaa
    24361 taattttatc aaccataatt aattaaatat atatcttttt aattgagata ataagcgata
    24421 taataagata aacaagtaat aagagggtga aagtatgtta atagctaaaa gaatattagc
    24481 aagtatagta gcaattcctt gctttttact ttccataatt gttattgccg ttaacataat
    24541 ttccatacct attttgcttg ttatacagat tcttaaaaaa gttgtgatcc tttttattac
    24601 attagtatgg attggtttta taggtctgtt tatttatgga ttaagttctt taggcttctc
    24661 tgaaacgatt agtatgttta cagtgcctac tataggtata ttaatcctta cattaatact
    24721 atctattttt acttttatct cagataaaat tcctaatttt cttggaattg ttagttcatt
    24781 tttcctttct atcccaaaat ttctatgggg ggctgaagaa actgaagaag ctgaagaata
    24841 aaacattcaa gggggaaaaa tatgttttca aagaaaaaat atgttcagtt tatagaacaa
    24901 agagatattg aattgccaga tacccctgta gaaatttaca ggggtattta tttacttgaa
    24961 caggaaaacg atcggctaac agacaagcat actaaaggtt ctacattaat attattaacc
    25021 gataaaaagg gaaatgaact aaatagacga ctaatccaat taccaataga acaaggtata
    25081 gagactattt tgactaacct tttaattgaa cctacctcaa ataaaaagca aagttcttct
    25141 aagtcgcaaa tgatattgaa tgatatagaa gaaccaaaaa taaagaataa aaagaagacc
    25201 gtaaattatc agacggtctt ctttttattt actactaatt tagcaaaaaa aatctacatg
    25261 gctttgataa tagttctgtt cctatttttc acaagttttt ttgtattaaa taatcattca
    25321 tcaacttcta ctgattctca aagctatcat gagctgttaa agaagaaaga ttatgaaaaa
    25381 ataataaaac aatatcctga aaaagaaaac gaattagtag aaaaactgta tagcgaaaaa
    25441 aattctaagg aattaaaaga attggcagag aaatctgatt cacagatagc tcttttttat
    25501 tgggatttct tgaatgagca ttggcaagca gtaactacga tgaaaaatgt tacaccaaac
    25561 gaaacaatac aagctatgcg tggttatgca tacttaaaac aaggaaaact agacgaagca
    25621 gaactaatta acaaagaaat tgataatcaa acattaaaag atcaaattta tcaatttaaa
    25681 aagcaagaag catataaagc tctgcatgaa aaagatatcg agaaggcaga gaaaataaat
    25741 aaagaaataa atgattctga actatccgaa gatattaaag tagctaaaag tatggttaat
    25801 ctacttcaaa aatatgaaaa ggacagatcg gattcaaaat tatcagaaga tgaaagaaaa
    25861 gaagctgaga acaattacaa attgtggtca gaaaacttaa aacaactagg aggaaacgat
    25921 aatgcataac aaaaagaaat ttttagtagt gggactattt tcagctgttt tattaggggg
    25981 tgcagttact tatggcatgt attctcaaca accacacaat gagactgaaa agacagaaca
    26041 aacaactaaa tcagagtcca gcaaacacaa aagtaagaaa tcagcatggg aagaaagtgt
    26101 gaaaggcaaa gaagacaaaa aggaaaaaaa caaacattct acaaagaaag ctgatgatat
    26161 attggctgtt attgctgata caccgctaat taaacaacaa cctaatcaaa acaaaaataa
    26221 tctaattgat agattagcag tagctttaga tgatcagact aaaaaagagg cagacagaca
    26281 agaaaaatta attattaaag acaaaaaatc tgtagatgag ccagtactag ttgatttgag
    26341 ttataaacct caacttgagg atactaaacc ttcaaataaa gagaacggta aaacagaaaa
    26401 taataaagat gaaaatagcg aattagataa aggaaatgat actaaacctg ataattcatt
    26461 acctgatcca ttgcctgtac cagagccaaa tccattgcct gatccaacac ctagtccaga
    26521 cccaaatcca ataccaacac cagatccaga ccctgatcca gagcctgatc caacaccaga
    26581 tccagaacct tcaattgatg aacaaattaa tcaatctaag gaagaactca atgattctag
    26641 gaaacaggct gatgaattaa ataaacaact aactcaagta aaagatagct tggataactt
    26701 acaaagtatt ggagcaagta ctgaaaagaa cgtggataaa gcagcattac aatggcaaaa
    26761 agttgctgac ttagtcaatg aatataatca acttacaaat gagatcaaga aattaattga
    26821 agaagacgga acagtattga caatcaatta tgacctttat aaagaaacgt atgaaaaact
    26881 aaaccaaaaa gtcactgaag taaaaactgc acaaaaagaa gcaaataata cgacaaacga
    26941 aataaataaa aatgtagaac aagcaactga tacgctaaat aatttagaag aaactaaaaa
    27001 agaatatcaa aataaacaga aagatgtttc tgaggtggat tctaacgtca attcggctat
    27061 taaccatgca caatccaacg aacaagttgc ttcagctgtt caagatgaga taaatcaagc
    27121 tgcacaatct aatgagcaac taaatgaaac taataagact gttggagaac agttgaatca
    27181 agttgatcca attgaaagcc aaactgatat tgctagcgct aaggagcaaa ctgctgatat
    27241 caataatcaa gctgaagaac aaaataataa tgttgacgat atgatgaatg atttttacaa
    27301 tttgccaaaa ccgagtgata gtgaagaacc tagcgttcca gaaaatacag atcaaaatca
    27361 agattcaaca agccaaccac aaaacataga taatgctagt gtttctcaaa acaaaataga
    27421 aaatgaacag gttagcgaaa aaacattacc agttactaat caaaatagta accaatccga
    27481 aattgaagat attcaaaaat aaaagtgagg aatgaaataa atgtcttata aagatagtga
    27541 agcaaaaaaa aataataaaa ccgctgaatt actttcacag gcagaagaag gtattaaaga
    27601 agtattatct tcagacaaat acaaaaattt tcttcgtgtt atgtctaagt ttcataatta
    27661 cagcttaaat aatacccttt taattcttat gcaaaatcct aatgctactc atgttgctgg
    27721 ttacaaaaca tggaaaaact cttttaatag acaagtaaat aaaggagaaa aatccattaa
    27781 aataattggt ggtcgtccct ataagaggaa agtagaagaa ataaagaatg ggcaaaaaga
    27841 agaaaaagaa gttgaaggta tttcattttt ccctgtttca gtttttgatg tttctcaaac
    27901 ttcaggagaa cctttaccgc aactaatgaa tgaattaagt ggagaagtaa aaaattatcc
    27961 agagctttat gttgccttga agcaaagcac caatttttct atagaatttg cagatataca
    28021 aggtggcaca aaaggatatt gttctccatt agaaaagaaa attgtgttaa ataatggtat
    28081 gagtcaagcg caaacaataa aaactctgat tcatgagatc actcatgctg atttacacgc
    28141 accagaattt gataaaaatt cgtcaataaa aactacaaaa tctacaaaag aagttgaagc
    28201 tgaaagtacg gcttttgttg tttgtgaaca ttatggaata gatacaaaag actatagctt
    28261 tccatattta gcagcttggt ctagtgataa agagttaaag gaattgaaaa atagctttga
    28321 agtcatttta aagcaagcag ataatttaat tcaaaaaata gacaagaatt tagcagaatt
    28381 acaaaaagaa gtgacaaaag aaaaagaaga aaaacaaagt actttgtcac tatctgatca
    28441 attagaagaa tttgaagata aagcaaaatc tttaaatgaa caacgtgaca aagaaaaatt
    28501 aattaataaa attcgccagc caaaagagca aaaagacgtt tctacactat agtttaaagt
    28561 agctgaaacg atctattttg cttttttaat ttatcagaaa aagtaacttt tataataaat
    28621 gagggatata aaaatgaaac aatatttaga ccaatggaat ataattgaag gagcattaac
    28681 tgaagaaaga attaatgaaa tacctgattg tctagaaaaa gatcatttat ttctaattag
    28741 aagaatgcta caaaaggaga attttgaacc caataatttt attgttgttg aatatccagc
    28801 tactggtata tattgctgta atcatatcaa caacgatcaa tattttattg tccaagaaga
    28861 aaaaaataaa ttagttccat actatactac ttgtgatatg aatgaaaagg gaattaataa
    28921 ttttccttgt acaagtatca aagaatccat gaaattaata gaaatgtaaa agagagggac
    28981 atataaatca tgcaaacatt tactcaacac gaattagaaa tcattagcgg acacaaacag
    29041 attacaggtt caaatgcaaa caaattaaac gtcataaaaa gcgaagttgg agaaatgctt
    29101 tcaatgttaa aaagtgattt aggaaaacaa tatattgaag atgatgaaca acgacattac
    29161 acattaaaaa attatcagtc tgtttatgat aaactcgaaa aaatgagtga agatgaattt
    29221 aagcaaattg atctaagcgg tattgaagaa ttggaataga aacggggatt ggggcagcgc
    29281 cccaaaatga aaaaagaagg attcgcgcaa gcggattttt cttttttttg tgcaagttac
    29341 cggtaacttg caaatcttgc tgtaagaccg cccccctgaa atcttcgatt tctaatcgga
    29401 gggcggtcac acagtgaaaa ttttcgtttt taaacaaaga taaaacacta aactagtgaa
    29461 aaaaacaaaa aatattggta aggaggggga aacatggagc aaaaactagc taaaactcct
    29521 gaaaatattc taaaaatagc caatacttat gatgattctg aaagaacgtt taggaaagaa
    29581 acacgttttt cagaaagaga aatatttcta ctaaattata aaatgagtca agcaaataca
    29641 agaaattttt cccaatacgc tcgtattatg tgtttaagtg gtttaatgat tacaacagat
    29701 ttttctgatt taaaaaattt aacgacagaa ttaggacgaa ttggaaataa tatcaatcaa
    29761 ttagctcaca gagctaatat ttcaaacagt gtttcaaaag aagacttttt agaattaaaa
    29821 acaaattatg atcaattgac taaattaatt aacgaagaat tactttttag aatgcgacgt
    29881 gctagagata accagaggtt tatttaatgg cagtgacaaa aatacaccaa ataaaaacta
    29941 ctttaaataa agcaattggc tatattacaa atccagaaaa aacgaataat ggaatgctgg
    30001 ttagtagtta taattgtcaa agtcaatttg cagaagttga aatgcaaatg actagggaat
    30061 atgcacgtga agtaaaaggc gattatcgaa aagtcggtgg gagtgaggtt ttagcgcacc
    30121 acttaatcca aagtttttcg cctgaagaca aagtgacacc agagcttgct catgaattag
    30181 gaagacaatt gattgatgaa ttgactgaag gaaagtttga atatgtgatt gccactcaca
    30241 tcgatcaaga acatattcat aatcacatta tttttaacag tgtttctttt tatgatctga
    30301 aaaaattcag aagtcaacct tatcgaacag caaataaaat taaagaaatt agtaatcgta
    30361 tttgtgctga acatgattta tctttatcac cgaaaaaaga aaaattaaaa gattcctaca
    30421 aatcttattc taacagaaga aataacacga gctttcgttc tgaaattcgt aaacgattga
    30481 tcatgtgctt aaatgaatca acttcatggg aggaatttga agaaaaagcg gatcatttag
    30541 gggtaaatat tgatcgaaaa gggaaacata tttcgtatgc tttattatcc gaaggacaac
    30601 aaagacggac tagaggggac aagttagatg acttagaaac atttacagaa agtaatattt
    30661 ctcaaaaact ttctgctaat caatcctaca ttaatcagtt gaaagaagcg attgaagaga
    30721 ccttcttttc tagtgacaac ttggaagatt ttagttttct tttggaacaa gagcatggaa
    30781 ttacctttca gttaaataaa caagatcaat ttgttttcca tttcaatgat gtaaatgatt
    30841 ttaagtggaa tgaaagcttg ctgccagata gttatcagat taaaaatcta aaagattatt
    30901 ttagagaatc ctatgagttt acgaatgact cttccttaaa ttccattgaa gaaagatatc
    30961 gtgaaaaaga aaaaagtgtg attgttcaag aagatacgcc tattcaattg caagaatttc
    31021 agatagagaa agcgaccaaa gaaggattgc tagtgtctat cgaacatgaa gacttaaatg
    31081 gtttagtgtt tgtcccaaat aattatgttg atgtaaatga agaaactgga gaatatacaa
    31141 tttggatcaa tgacaaattt gattatacgc ttactgacaa acggacaaac gaacaaacta
    31201 gttttactgt aaaaggcgaa gggatcattc gtggactgga aaaaatgcaa gggattcaac
    31261 cacaagagat aaaactttct agcaaaaata ttttatctat gagtaatcgt ggtgtatcta
    31321 tttcgatacc agaactgaat atcaagcggc tctttattcc tagtgagtat gttgtaatcg
    31381 atgaaattag taaatcttgt tctatcttaa ttggagaaaa gtggaattac tatgcagaaa
    31441 cactccctga gaacgatgat aattcaaata aaaaattacc ttatcaaaaa tttactggac
    31501 gttctttaat cagtagttta aaagaaactc ctgaattact tgatgtgttt ctaaaaccta
    31561 aatttgatca gctacattat caatcaagaa aacgatatac taatcaatta gtcgaagctt
    31621 taaatacgat tcgtgaagaa aaaatagttt cagcttcaca attagaacag agattgaatg
    31681 aaattgttga gcaaaaaaac caagcaaaag agaaaatagc tgagattgat ggaaaaataa
    31741 aaaattataa caatgtcgca aaacttttag taacttacga aaaatattta ccgatcatga
    31801 atgaaattga gcgtgctaca atgcttcaaa aaatgaaatt agaacaaaag tacaaagaag
    31861 aagtacgcca atttaaattt gctgaaaaga aattactagc ttcagataat ctacgtcctg
    31921 atttaacgaa agaaaagata atatctgtgg cgaaaaatca agagaaacag aggaaacgac
    31981 ttatagaggg ctataagcat tatgaaaata aattaaatag attgattgat gttcaggaaa
    32041 tattgcaaga actagataga aatggattat ttgatcttag tgggtatcgt ttgattgata
    32101 gagaagaaaa gctaacggac aagatcgaga agtatgaaaa agaagtagaa gaaactcaac
    32161 aaaaaaatgc aaaagagaag agaaaggaac acgaaatata aataactgaa aacactatat
    32221 attccgaaaa gtgaatatct ctattcataa aataatcaac atatttaaaa aatttaatta
    32281 gcttttttag tcaagctaaa gtgctttatt ctatgatata atgttactgt agaaagtttg
    32341 tggcggtttg gcaaatccaa ttgaaggagc gtggtgccta tgggcttatt agcttatcgg
    32401 acgtactctg tagaaaggaa atgcctgatt tgttctcatt ggatcaaatc attgctatta
    32461 tcggagcagc agcagtagtt attactgccg tagcgaaagc tagcgattcg attttagctt
    32521 ggttaaagtt caaaaaagaa caaaaaaaat agagccgtcc taacttttgg cagagtagac
    32581 aggctctaaa gctttatata catgccatcc gctttgaacg gactacacat taggggctat
    32641 gttagagcat agctccttat ttacttatag tataacgtag atagagaaaa aagaaaagaa
    32701 ataaaggcta gttttgtttt gataaaagct aacctttatt tttttgttca catttcaaat
    32761 atttgagaaa gaattaaagg aggtggtgtc gttagcaacg actacaactt gaaaacagct
    32821 gtctattaaa ctatctcttt ttatgtatct tttgggtata ctctaatggt acaaatccat
    32881 atttgcttaa agcgttgatt tttcagcgtt ctttctttat tgcaaagtgt accctaagac
    32941 ttgtatacta atagtaaata gattggatag gaatgatggc aaatgtattt agcttattta
    33001 agagtttctt ccgacgatca aagtttagct cggcaacata agctaattga aaactggtca
    33061 gtcaaaaata atattgatga agacgattta aaaattttcg aggaaaaagt ctctggaaaa
    33121 aatattgaaa acagaccaga gctgcaagag cttatttctt tcatacgtga acgagatacg
    33181 attattattc ctagtcttga tcgattagca agaaatagta aagatacaaa agacttactt
    33241 caattgtttc gtagtaaagg tgcttctatt gaaatattag acctaccgtc gtttaatggg
    33301 gtaactgacc ctgcgttaag agacttgcta acaaatttag tcatagaagt gtttagctat
    33361 gttgctgaaa acgaacggaa aaaaatcaaa gagcgtcaaa aacaaggcat tgaaattgca
    33421 aagaaaaatg gtcgttatac tggtaaaaag attcaatacc atgccaatgc gacaggaaaa
    33481 aacaaattga tttacgatga aattgttgat ggtctgaaga aaaaagaaac tatttctaaa
    33541 atagcaaaga acgcaggggt tacaagaaaa accgtttatc gagtaaaaag agatttagga
    33601 atgtaatatg ttccagttag aaagaagcgt aaataatgca agatatagaa atcggtaaaa
    33661 tttattattg tgaagttcct agtttggaag gttcttttga agttcaagtt ttacaaattt
    33721 tcgtttgtca aattaagtta gacaaatcat cttttgtgac gtaactcaaa aatacttcca
    33781 ttggtgtccg atagtgtaat gattttctag gaatatgatt tcgtttcgat gccaccgatt
    33841 ggataaaggt ttcagataca ccattaaaat ccatagcttt atacaaacca tctttacgta
    33901 ataagccatt tgaatgttca ttcaatcctc gttgagaagg tgttcctgga tccgcaaaat
    33961 aaattgaaat atcgttggta ttactaatct ttttccaatt tgagaattct tttccacaat
    34021 caaatgtgat ggatttaaat aagttttttg ggacacaacg aaaccattga ttcagcctat
    34081 tttcaatgtc tttagcctgt ctgccttcgg gtttcaaggt aatgatgact ttagatagcc
    34141 gttcaactaa tgtgatgacc gcgcttttat gttttccacc cacgatagtg tcaccttcca
    34201 ggtgaccaaa ttcatgatca aactgggtat agtctgtctt tctgtctcgg attgaccggc
    34261 gaaacccttg ttttcctctt ttttctttat gaccgtttgg ttttcttttt cccttcattg
    34321 gtaaatcgtg agtgtcaaag gttttatctt taaacattcg atacagtgtg cgtaccgaac
    34381 aagcaatagg aaactctgct cgaccaataa ggacatcagg agcccaccct tgaacaacct
    34441 ttttttgaat gtattcctgt tgctcatcag gtaaaacaat cggatgtctt ccgcagttac
    34501 gtttgttttt cttatattgt ttatagtagc tcattgcgct tccaccagat ttaagaaaac
    34561 gatagacctt ataaatagtt tgtcgagaac gttgtaacag attggctact tttgaaacag
    34621 gttgtgattg attgaaataa gcttctatca ttacgagttc agttggtgta agatggttat
    34681 aggtcatttg tactcactcc ttataattct ttcgtcggaa ctattttgag tgtagcacaa
    34741 atgacttttt ttagttgtct agcttaattt tacaatcggc gaatgctaaa agacaactgt
    34801 gttttagtga gagtcgtacg ttgtacatta atgcaaagta aatatttaaa gaaaagcaaa
    34861 tatcgtttta ttgtcaatat caagtcccta aaaggacgat cgttacactt ttaataaaga
    34921 gatggaggac taaataaaaa tgaagaataa actgacatta ttaatttgtg caaccatttt
    34981 gtcaacgtgg gcagtcccta cacaaaatgc ttttgcagaa gaaacaggga atgatactac
    35041 gcagcaaaca gtgactagca acagttctaa tgaagaacaa actgcaatta taaatggaga
    35101 acaagtaaag ttagaagcac cagtgaaaga aggacagtct gaagctgaag cgactcaagc
    35161 accaaaagaa gagttacaac aagatcaaat gagtcggttt gctcgtagtg cagtaagaac
    35221 aatacctatg tatcgcatgt ataatccaaa tagcggagaa cacttctaca ctcaagatac
    35281 tggagaacga gataatctaa gaagaattgg ttggaattat gaaggcatag gttggcaagc
    35341 accaacaagt ggcgatccag tttatcgctt atataatcgc tataatgggg aacatttcta
    35401 tactttaaat gccaaagaac gtgataatat cacaaaacaa gggtggacgt atgaaggaat
    35461 tggctggtac tcttataaag gtgctaatgg tattccagtt agtcgcttat ataataaacg
    35521 agtgaattgg caccactaca cactagatga acatgagaaa aacgtgatta gtaagcaagg
    35581 ttggaattat gaaggcgtag gttggtacgc agtcggcaat ggacaaccaa gtaatgacga
    35641 ctataagctt cttggcgtaa agaattacaa tcaatatgct ttaggcgctc caagtggctg
    35701 tgaaggggct tcattactac aagcattaca atataaagga aagatcacaa attggagttt
    35761 aactcaattt ttaaacacga ttcctaaatc tccaaatggt aatccaaaca atgggtttgt
    35821 tggtagtcca ttcgttgaaa attcttggac ttactcagct atttatcctg ctccattaac
    35881 aacttgggga caaaaatatg gaaatgtaca gaatatctca ggtagttcta tgaatacatt
    35941 gcttaatgaa gtgaagaacg gaaatcctgt agttgcatgg gtaactatca atttccaacc
    36001 aatccgttgg ggaaattgga gttttggtgt agcagctaat aataatcacg cagtgacact
    36061 tgatggatac aataaaggaa gtaatcaagt acatgtatct gatccaatta gtggctctta
    36121 ttggatgaat cgaacaacat ttgaaaatat ttacaacgca cgaaaatatg cagttgtagt
    36181 tagatagcat tgtatgcttt aagatcattt gttaatatta agaaacggaa ctcccaaaaa
    36241 ttccgtactc taatttgcag tctctcactc ttttggagtg agagtttttg tctagtttcc
    36301 aaaatgtcta ataaagtgat acaacgaagt gggttgatca tacaaatcaa aaaaagaagc
    36361 ataggtaagc tattatcttg cttctttttt tgtgcacata actatttctt ctttacaaaa
    36421 acgaacatac gtttgtataa tgtagaagaa tggagtgtta tttatgatgg attattcaaa
    36481 agaaccaata aatgattact ttttgataga catgaagagt ttttatagtt ctgtggaatg
    36541 tattgagaga aatttagatc cattgacgac tgaactagtc gtcatgagtc gtgctgataa
    36601 tactggatca gggttgattt tagcttcttc accagctgca aagaagaaat atggtatttc
    36661 taatgtcagt cgaccaagag atttaccaca accatttcct aaaacattat atgttgtgcc
    36721 accacgtatg aacctttaca ttaagcgtaa catgcaagta aacaatatct tcagaaaata
    36781 tgtagcagac gaagatttat tgatctactc gatcgatgaa tctatcttaa aagtgaccaa
    36841 atcactgaat ctttttacga ctgtagggac aagaagtcag cgaagagaga aacttgctca
    36901 attgattcag caacatatta aaaaagagtt aggattgatt gctacagttg gtgtcggaga
    36961 taatccctta ttagctaaac ttgctttaga caatgaagca aaacataatg atggattcat
    37021 tgctgaatgg acgtatcaaa atattactga aaaagtatgg aatattaatg aaatgacgga
    37081 tttttggggt attggctctc gaatgaaaaa aaggctcaac caaatgggta tcatgagtat
    37141 taaagaccta gctaattgga atccatacac cattaagagc cgtttaggtg tgattggctt
    37201 acagttatac tttcatgcaa atggtattga tcgaacagac atagcaattc caccagaacc
    37261 aacgaaagag aaatcttatg gcaattcaca agttttgccg cgagactata caagaagaac
    37321 tgaaatcgag ctggtagtaa aggaaatggc tgaacaagta gcaatccgta ttaggcaaca
    37381 ccactgtaaa acaggttgtg ttcatttaca cattggaacg tcgatcttgg aaacgaggtc
    37441 agggttttca caccagatga agatacctat cacagataat acaagagagc tgcaagacta
    37501 ttgtctgttc ttatttaata aatactatga ggggcaagaa gtccgacacg tcggaataac
    37561 ctatagcaag ctcgtataca ctgattcgct tcagctagat ttgtttagtg atccgcaaaa
    37621 acagattgat gacgaaaagc tagataaaat aatagataaa atcagacaaa aatatggttt
    37681 tacgtcaatt gtacacgctt cttctaagct tgaaggggct agaagtatta caagaagcac
    37741 gttagttggt ggacatgcag gcggcgttgg agggcttaaa aatgattgat tataacgatc
    37801 gaggacgatt gaaatgggca ggattctatt tatcagatca tactgaagaa atcgatgctg
    37861 aaaataagca acgagtcaat caaaacttag caaaaaaaca aatgacgact gaagagattt
    37921 ctaaagtatt gaatgctgca gttataaaaa atagatcagt atgtattcaa aaagaagaac
    37981 gaaatgctga aggatactat ccagatgata ttatcggtaa gatcttagga agtgatgaac
    38041 tgggaatcta tgttggaaaa aacaaagttc actacgatga aatacgtcat attgaatttt
    38101 atcaggaact taaatggagc tgtttagaat gaacattata aagcaatatg agattaaata
    38161 tatatcactc gaaaatcttt tagaaaaaat atggggacat ggtcaacaac taattaatga
    38221 aaataagaat cgactgtttc aaattttacg tattaataat agctggcggg tacttaattt
    38281 ttggatatca tatattgaat tatagcgctc ttcacttttc ggtataaata aaaaggatag
    38341 a
//
LOCUS       DACDLM010000022        36568 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.022, whole genome shotgun sequence.
ACCESSION   DACDLM010000022 DACDLM010000000
VERSION     DACDLM010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36568
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.022"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(26..1522)
                     /gene="lysS"
                     /locus_tag="IV356_001158"
     CDS             complement(26..1522)
                     /gene="lysS"
                     /locus_tag="IV356_001158"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HAP9014860.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="IV356_001159"
     CDS             complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="IV356_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HAP9014861.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="IV356_001160"
     CDS             complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="IV356_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HAP9014862.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3742..5853)
                     /gene="hflB"
                     /locus_tag="IV356_001161"
     CDS             complement(3742..5853)
                     /gene="hflB"
                     /locus_tag="IV356_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HAP9014863.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="IV356_001162"
     CDS             complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="IV356_001162"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HAP9014864.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="IV356_001163"
     CDS             complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="IV356_001163"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HAP9014865.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8053..8523)
                     /locus_tag="IV356_001164"
     CDS             complement(8053..8523)
                     /locus_tag="IV356_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HAP9014866.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8569..8994)
                     /locus_tag="IV356_001165"
     CDS             complement(8569..8994)
                     /locus_tag="IV356_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HAP9014867.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9061..9330)
                     /locus_tag="IV356_001166"
     CDS             complement(9061..9330)
                     /locus_tag="IV356_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HAP9014868.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9341..10936)
                     /locus_tag="IV356_001167"
     CDS             complement(9341..10936)
                     /locus_tag="IV356_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAP9014869.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="IV356_001168"
     CDS             complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="IV356_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HAP9014870.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14489..15049)
                     /locus_tag="IV356_001169"
     CDS             complement(14489..15049)
                     /locus_tag="IV356_001169"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HAP9014871.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15402..16376
                     /locus_tag="IV356_001170"
     CDS             15402..16376
                     /locus_tag="IV356_001170"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAP9014872.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16546..17946
                     /locus_tag="IV356_001171"
     CDS             16546..17946
                     /locus_tag="IV356_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HAP9014873.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18024..18746)
                     /locus_tag="IV356_001172"
     CDS             complement(18024..18746)
                     /locus_tag="IV356_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP9014874.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18825..19331)
                     /locus_tag="IV356_001173"
     CDS             complement(18825..19331)
                     /locus_tag="IV356_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAP9014875.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19454..21253
                     /locus_tag="IV356_001174"
     CDS             19454..21253
                     /locus_tag="IV356_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HAP9014876.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21321..22895)
                     /locus_tag="IV356_001175"
     CDS             complement(21321..22895)
                     /locus_tag="IV356_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014877.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="IV356_001176"
     CDS             complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="IV356_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HAP9014878.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="IV356_001177"
     CDS             complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="IV356_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HAP9014879.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24672..25310)
                     /locus_tag="IV356_001178"
     CDS             complement(24672..25310)
                     /locus_tag="IV356_001178"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HAP9014880.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25311..25961)
                     /locus_tag="IV356_001179"
     CDS             complement(25311..25961)
                     /locus_tag="IV356_001179"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HAP9014881.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="IV356_001180"
     CDS             complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="IV356_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HAP9014882.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="IV356_001181"
     CDS             complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="IV356_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HAP9014883.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29104..29844)
                     /locus_tag="IV356_001182"
     CDS             complement(29104..29844)
                     /locus_tag="IV356_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HAP9014884.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="IV356_001183"
     CDS             complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="IV356_001183"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HAP9014885.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31215..32153)
                     /locus_tag="IV356_001184"
     CDS             complement(31215..32153)
                     /locus_tag="IV356_001184"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HAP9014886.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32146..32637)
                     /gene="def"
                     /locus_tag="IV356_001185"
     CDS             complement(32146..32637)
                     /gene="def"
                     /locus_tag="IV356_001185"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAP9014887.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32652..35060)
                     /gene="priA"
                     /locus_tag="IV356_001186"
     CDS             complement(32652..35060)
                     /gene="priA"
                     /locus_tag="IV356_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HAP9014888.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35313..35618)
                     /locus_tag="IV356_001187"
     CDS             complement(35313..35618)
                     /locus_tag="IV356_001187"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAP9014889.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="IV356_001188"
     CDS             complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="IV356_001188"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HAP9014890.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYINKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
BASE COUNT         9886 a         7988 c         6706 g        11988 t
ORIGIN      
        1 aattccttag acagctttta ttcgattatc tcattgttgg gaatagcaaa acatcccgaa
       61 ttgattgtgc atcagttagc aacattacta atctgtcgat cccgatgcct agaccaccag
      121 ttggcggcat accgtattct aaggcttcca agaagtcttc gtctacaccg tgagcttcgt
      181 catttcctag ttcacgttct ttttcttgcg cttcgaatct ttctctttga tcaattggat
      241 cgttcagttc tgtaaaggca ttagcaaatt cgcgccccac tatgaatagt tcgaatcgat
      301 ctgtgaatcg aggatcttct ggatttttct tcgctaaagg cgaaacttcg actggatgtc
      361 cgtatacaaa cgtcggttgt gtcaatgttt cttcaacaaa tgtttcaaag aattcattga
      421 taacatgtcc gacacccata gcttcggtta cttctacatt gtgtttttcg gctaaagcta
      481 atgcttcttc caatgtcatt tcttgccaga agtctacacc agtttgttct ttgattgcat
      541 ctaccatatg gatgcgttta aagtcacttt ctaagtcgac agcttgtcca tcatatgtga
      601 tttttgctgt tcctagtact ttttcagctg cgttacggat aataccttct gtcagattca
      661 ttacatcatt gaaatcagta tatgctgtgt atgcttctaa catcgtaaat tctggattat
      721 gtgtagtatc aattccttca ttacggaaaa cgcggccgat ttcataaact ttttccattc
      781 cgccaacaat tagtcgtttt aaatgaagtt ctagcgcaat acgcaaatat aaatcaatgt
      841 ccagtgcatt atgatgcgtg ataaatgggc gtgcggcagc tccacctgcc tcattgtgca
      901 atactggtgt ttctacttca atatagccat tgccatctaa atagcgacgg atttcgctga
      961 taatttggct tcgtttcata aatcggtcaa agctttcgcg attactgatt aaatccaagt
     1021 agcgttgtct gtagcgttgt tcaatattcg ttaagccatg gtatttatct ggcagtggac
     1081 gaagtgcttt tgacaaaatc gtgatttctg aagctttgat agaaacttcg cctgtgtctg
     1141 ttttcatgat ttgtccagtt acaccaaaga aatctccaag gtctgcatgt ttgaatactt
     1201 cataggcctc atcacctact tggtcttttc ttacataaat ttgaatttgg ccttcacgat
     1261 cttgtagatg cgcaaatcca gttttccctt ttcctcggcg agtcatcata cgaccagcta
     1321 cactagcggt caatcccatt tctgctagtt cttcttttgt tcttggatca aatagttcat
     1381 gcaattcttc tgagttgtgc gtgcgttcaa atcgttttcc aaatggatcg attccatctt
     1441 cacgcaattg ttccattttt tgacgacgta caagcatttg atcatttaaa tcttctactt
     1501 gatgttgttg ttcctgtgtc acaaaagttc ctccattctc atgttaatct ctttcctata
     1561 atgccaatga aacacaaaaa aagcaagccg aacttggaat ttcggcttga aaattcacga
     1621 aaaacttaga aatcacaacg tttgtttcaa tagtactttt tccgcttttt ctacaaattg
     1681 atccagcagg tcattgattt cttgctgttt ttctgtctga ttgattgcta ctttcacttt
     1741 cgctgctcga ggaatccctt ttaaataata agccgcatgt gttctgaatt ctctacaagc
     1801 tactttttct cctttgagat ctgctaagcg ttgtaaatga agtttagctg tagcaatttt
     1861 ttcggctggt gttggttcag gaatcagttc tcctgtttcg agataatgct gtgtgcggtg
     1921 aatcatccat ggattgccca gcgctgcacg accaatcatc acaccgtctg caccgacata
     1981 gtcaagcatc cattttgcat cttctggcgt tttgacatcc ccgttcccca taaatgggat
     2041 cgtcaaatgt tttttcactt ctttcaatac ttcccagtcc gcttttcctt catacatctg
     2101 aacccgtgta cgtccatgca tagcgatggc acttgctcca gctgattgtg ctgctaatgc
     2161 attttctaca gcaaagacgt gctcttcatc ccaaccaata cgcatcttga ttgttactgg
     2221 gatatttact gctgaagaaa cagcttggac catttcgtat actttctcag gatctaaaag
     2281 ccattttgct cctgcttctg ctttgattac tttatttact ggacagccca tattgatatc
     2341 tattatatcg gcagctgtgt tttcttcgac aaattgagca gcttcaacta gactatcttt
     2401 atttccgcca aatatctgta aacttaatgg atgttctgtt tcttcaatgt ggagcatctc
     2461 taaagttttt ttgtttctga aatgaatacc ttggtcactg atcatttcac atacgactaa
     2521 gcccgcacca aattctttga cagtgactcg aaatgctgaa tttgttattc cagccatcgg
     2581 tgcaacaacg acacgattag ggatttccac attgccaatt ttccatgtgt gttccactta
     2641 aatccctcct aaggcttctt tcttcaatcc atctaattct tcttcgctat acttgtattt
     2701 gttattacag aaagaacaaa ccgcttctgc accgtgatct tcgtctatca ttgcttggat
     2761 ttcttctgca cctaacgcga taattgcttc tgcaaatttt tcttttgaac agtcacattt
     2821 gaattgaaca ggcatttttt ccaaaatgtt caattcttct gtaccaagca atcctttcaa
     2881 tatttcttct ggtgtctgtc cttcatctaa gagggtagag attcttggtg tcgtttttaa
     2941 ttgttcttcg atcttgctga ttgtttcttc atcggcacct ggcatgattt ggatcatgaa
     3001 tcctcccgcc gtcttgatgc tgtcgtcagt attgaccaat acactcagtc caacagctga
     3061 agggatttgt tctgagatag caagatagta agtaaaatct tcagcgattt ctccagaaac
     3121 aatcggcgtt tgcccagaaa aaggttcttt taatcctaag tcttttgtga cagtaaacat
     3181 tccttgtgtt ccaactgctc cccgcacatc gattttacct tcactattta gaggaagact
     3241 gagatgcgga tttttgatgt aacctttcac atctcccttt ccatttgcat ctactacaat
     3301 tcctgttgct ggaccatcgc cttggattcg aacagttagt ttgtcttctc ctttgagcgt
     3361 cgcaccaagt agcagactac cgaccaatgt ccgtcccaaa gcagctgagg aggtgtgcca
     3421 agtatcatga cgtctttgtg cctccgctac ggtatttgtt gcttgaacgg cgtatgctcg
     3481 gacgaatccg tcgtgagcaa gtgccttaac caaataatct ttcatttgtt atgtactcct
     3541 ttttccgttt ttaaactcat agtgaatcat actagcaact actgcttttt tcaactttgg
     3601 aatgcttctt ttaaaaataa ttcagaatca tctagaaaac aggacatcac cctatttaca
     3661 acttaaataa agaaatctcc cgaaaaccgg tttttgttcc ggttttcggg agtcatatca
     3721 gatcaattga cctatatttt tttatttgta ttgatcgtct gaatgattat cttctgattg
     3781 ttgagaatct gaatcatgtt ctgctttatt ttcctcattc agttcatgtt ttgcttcttc
     3841 aaaatcacgt ttttcttccg cttgtttttc agcgtctttt tcttccaaag cacgttttgc
     3901 ttcttcaaaa gttttcgctt ctttttcgct tggataatca tttgactcag taccttcagg
     3961 catcacaccg tgttcaaaca atgacttgat tgctttggca tccaatgttt cgaattccaa
     4021 aagtttttca gcaatcagtt tatgctgtgc acgatgagct tcgatgattt ctcgagcttt
     4081 atcatgagct tccatcaaga tttttcgtac ttcttgatca atctcgaaag cgacttgttc
     4141 cgagtaagct tttgtttgac catagtcgcg gccaacaaac acttgatggt ttccttcata
     4201 ttgaacagga cctaaacgat cactcattcc atattctgtt accatgcttc gtgctagagc
     4261 tgtcgcttgc tcaaagtcat tggaagcacc agttgattgg acattgaaga tgatttcttc
     4321 agctgtacgt ccaccaagta agcctacgat ttgttcaaac atatcttctt tcgtcatcaa
     4381 gaactgatct tcttttggta aagcgatcat atatccgccg gcgcgtccgc gagggatgat
     4441 cgttactttg tggacgaccc gagcgcgact caatactaat ccgacaatcg tatgaccagc
     4501 ttcgtgataa gcaaccattt cgcgttcttt tttgctgatt acgcgatctt ttttagctgg
     4561 acctgcaatc acgcgatctt ccgcttcatc gatatcagaa gcatcgattt tctttttatt
     4621 tcttctagca gctactaacg ctgcttcatt caagacattt tctaaatctg ctccggcaaa
     4681 acctggtgtc tgttgagcca caactttcaa gtcaacgtca tctgccatcg gtttattccg
     4741 tgcatggact cgcaagattg cttcacgacc ttttacatct ggacgtccaa ctaaaatctg
     4801 gcggtcaaaa cggcctggac gtagtaacgc tgggtctagt acatcagaac ggttggttgc
     4861 agcaatgacg attactcctt catttccgtc gaagccatcc atttctacaa gcaattggtt
     4921 caatgtttgt tcgcgttcat catgtccgcc gcccataccg gcaccacgtt gacgacctac
     4981 cgcatcaatt tcatcaatga aaatgatagc tggtgcgttt ttcttcgctg tttcaaacaa
     5041 atcacgaaca cgacttgctc caacaccgac aaacatttct acgaaatcag aacccgagat
     5101 cgagtaaaac ggtactccag cttctccggc aacagctttt gctaataagg ttttacctgt
     5161 tcctggaggt ccttctaaaa gtacacctgc cgggatacgg gcacctaatt caacaaatcg
     5221 gcgaggatct ttcagaaatt caacaacttc aactagttct tgtttttctt cttccgcacc
     5281 cgctacatca gaaaaacgta cgcgattagc ttttttgtct gcttctttgg cttttgattt
     5341 accaaagttc atgacacggc cgccaccgcc accgccgccg ccttgttgtc ccatcatcat
     5401 gtaaaagaaa aagatgatga ttacgattgg caagaagcta agcaataggg aaacccatat
     5461 accgctgctt gattcttctt ttactgttgt agcaactttg ttttcttttg ccagttctgt
     5521 tacttggctc aatgttgtat catttggcaa aatgattgtt gtgaaatggg tagtagtcgt
     5581 atctgttgaa cctaagatag ctaacccacc gctgttagcg acggtctgct gttctttgta
     5641 ttcaccagtg atcttatata caccatttgc aggctgcact tcaaattctt tgatcttgcc
     5701 tgcttgtagt tgttctgtga attttgagta ctcgatatct gacgatcgct ggccgttatt
     5761 accaaaaatg aaataaacga ccattaccat cgctaagatt acgaggacat aatacaaggc
     5821 atttttcatc atgccgttgt tctttttgtt catagttgcc ctccctaagc gtcaatttaa
     5881 tttaacagtt ttttatcaat cctgaccatt ctattgtacc ataatttaat tgagatacag
     5941 cattaatttg attgataaac actaggtttc aatacaccga tgtacggaag gttacgatat
     6001 gcttctgcat aatccaagcc ataaccgacc acaaattcat ttggtacgtt gaagccaaca
     6061 taatctgctt cgatatttac tactcttcct tcaggtttgt caagtagtgt aacaattttg
     6121 actgattttg ctttgcggta tttgaaaaga tccactaaat aagcaagtgt tcttccgctg
     6181 tcaatgatat cttcaacgat caacagatcg cgaccttcta cattcgtatc taagtctttg
     6241 acgattttta cttcccctga cgagactgtt gcattcccgt agcttgaaac atccatgaaa
     6301 tccaattcca aatacgtatc gatagaacga acgatatctg ccatgaatgg taccgctcct
     6361 tttaagacac ctactactag gggattggtg ttttggtaaa tttctgttaa ctctttgcct
     6421 agttctttgc aacgaacttg tatctcttct tgtgagatca aaattctctc aatatccttt
     6481 tccaacatca ggttctcctt ccaattgctt ctttttgata tttgtaaaga agtatgtagt
     6541 gtattttatc agtttcttca cgaatactca aatatgaaaa ggcaaaaggt atcaagctat
     6601 atatatttct tttggcatct gtaatgatcc aagcatgctg cctttgtgaa ttaggtactt
     6661 tctgatcgat aaaatatcta gatacttttt ttgtgagatt ctctgttaat ttaatgcggt
     6721 ctcctgcttt tcttttttcg acatacagtt gcacatcagc aggaatccaa atgtcatgag
     6781 aaaatagaga ccatgaatct gttgctttga tgtcccctgc attttcaggt ttgaccagac
     6841 caatccattc tgtttcattc aaatatattc cttgttctgg aatcagcaac aagcgctggt
     6901 cttctgtctg gctagttgct tgtttttctt ttttagagag tacaacaaaa tgatactctc
     6961 ttttcagtat ccaattattg ccaatactga gttgccattg gctttttttc tgttgccact
     7021 ggtctaaaat cgactccatt tgttgttctt tcaaaataat tcctgttttt gagaatgctt
     7081 tgtcgaaaaa ggagtaaaaa aaatagtatc gttcagcatc tgtcatttct tcaatcattt
     7141 ctgcagaaaa tcgaaattgt tcctcccact gttcgacttc cttttcgatc aactgtccca
     7201 tatatttttg aatgacttgg tctgcccatt ggatctgttg cgaaaattgc tggaaatgtc
     7261 tcaacgcctg tgtattttct tgtttcaatt gaggaactac caaatgacga agccgatttc
     7321 tctggatatc taacaattgg tttgtctgat cctcaaagta aacaagctgc gattccgctg
     7381 cataagtata taggtcttct ttgctaaaac tcagcaacgg acgaatcagt ctgcccgtag
     7441 caaatggttg tacttctttg attccagaaa aagtatttaa ctgtccccca cgaacgattt
     7501 tcattaacac cgtctcgatt tgatcatctc cgtgatgagc agtcatcaac gtgtcatatt
     7561 gtccttcttc catcacgcga gtgaattctt gataacgaaa gttacgagct tctgtttcta
     7621 tggcggattt ggctggatct tcccaaatac ttacatataa agggagattc ttctcttcac
     7681 aatatgagcg aagataggca gcttcttctg ctgattcttc tcttaattgg tgattgatgt
     7741 ggacgatacc taaagaaaaa ccgatttggc gttgcacttg taaaagtaaa tggagcaaaa
     7801 ccatcgaatc aacaccacct gataccgctg ctaaaattct cgatccttgt tgccagaatc
     7861 cttgttcatt cccgtgccga ataaatgact gctgtaatag cggtgctttt ttcccgcctt
     7921 tttcaacgtt catcctttcc acaccctttc ttcctaaaaa aaagagagcg ggaaaacgtc
     7981 taaaacgaca attaacctgc cctctgttga tactatgacc caaatagtcg cactatcatt
     8041 atttgcggct ttttagctgc gacgtccgcc acggccaccg cgctttcctt ctgtgtttcg
     8101 cttcaatgaa gataagcggt catcgctatc tttcaaaaat gaactcatca atgaatcgaa
     8161 gtcttctttt tgagctgaag gttgactgcg agaaaaagat tttttctgtg ctggacgatt
     8221 tcggttgtca cggggatctt tttgttgata ttttttagga cggctttctt ctccagattc
     8281 agcaggttgt tcctgcgctt tccggataga tagtccgatt tttccatcat catttactga
     8341 aataacttta actgttactt catctcctac acttaaaaca tcatggatgt cttttacata
     8401 gccatttgac acttcgctaa tatgaactag acccgttttt ccagcaccta gatcaataaa
     8461 cgcaccaaaa tttgtgattc ctgatacttt tccttgcagt tttgctccta cctcgattga
     8521 cataaaaaaa atgttcctcc taattatttc ccttttttat attcctgctt attttgcagt
     8581 tgtagaacta gttgattgat ctgtttcatt tgtcgagctg tctgtatttg attctaatat
     8641 aggataaact ttttcaccgt cttttgagta aaagaatttg cttctggcaa gtttagctac
     8701 atactcatca tctttcagca atgaaacatc ttggtgcagc tgatcaacgt ctgcgttgac
     8761 ttctttcatt tcagtatttg cttcgactct caattcgttc aattgatgca tcctttgcat
     8821 gtcatggaaa atctgcacac ctattatcgc gaaaatgacc aaagcaccaa caaaaattgc
     8881 agccagtctg cgtcttcgaa aaatcagttg acgttgttgt tgctgaaatt cagcatactt
     8941 tttctttgca tattccgtat ctagcgcagc gattttattg ctttttttcg tcacttggat
     9001 tcgctccaat ctttttgatt gtctttttca ttataccaat atcgtgaaag cttgtctaat
     9061 ctatttctct agtgtttctg tgcgattttc agaaataatt tcgtacattt tttgtgcatc
     9121 ttcttttttg gttgattcat gtaattccgt aattttcact tccaacgttt tgttgccaaa
     9181 ctggactttc aaaatatcgc ctactttgac atcactggaa gatttcgcca atttaccgtt
     9241 gatttgaatt cttcctttat cagctacttc ttttgctact gatcgtcttt tgatgattcg
     9301 ggaaattttt aaaaatttat ctaatcgcat atcttattcc tcacttttta atttttttat
     9361 ttaatcgcag gattttctta ccaaaaggca acattagcca ttctcgtact gtaaacagac
     9421 gaagacgaat cactgcataa atgaacacag aagccccgat cccaactcct atcacgctga
     9481 caaaaaaagc agtggaacga tgagttacag gaccaaatac tatattcaat acaccataat
     9541 acagcagcag tactactgtc atacaaagaa ggctgaacat caacttccgt ccaaaatgcc
     9601 gttctttcca aaaagcattt agctcttttg tttcaattcg aacaaaatac caaagcgtca
     9661 cacctaatcc taaaagggta gacaggcttg cacctgctgt tcctaataaa ccggtcagaa
     9721 aagaagtagt caatcctttt accaatagtc cccatcctgc gccttttaaa gaagggcgaa
     9781 acgagttctt gctttgagca atactttgat aagcttggat gactgcagtg aaagcaatgg
     9841 aaaaaacaaa taatacaagc gctgcatttc ccgcataatc tttaaacaac gcataattga
     9901 tataagggag cagcaaggct aatcccaaag acgcagctaa tgctaaagcg gtcgtcaatc
     9961 taagatagat tttggctgtc tgtaaaaact gacgatagat ccggttggtc aaatgacgag
    10021 tcaacgcagg caggaatgtc gcacttaatg cagtggcaat cactaaacct aattgtacta
    10081 aaggctgacc tcgatcatag accccttttg ctatcttcgc accgtattct gacagtccgt
    10141 aaacttccaa agcatttttt acaaagaaag agtcgatcag ctggaaaaag ataagcaatc
    10201 cactataaat cgaaaccagt ccgccttcta ccagaaaacg ccggatcaag ggctttgacg
    10261 gctgtttgaa caatggaaac cgtcggaagc ttaacgctcc tccatgaatc ttttgttcat
    10321 agtagtgaag gatcccatat gcgcataaac cgccaaaaac agctccactc attgctgccg
    10381 tccctgtttg gtacaccgtc catccaagct ttctaaaagc aaacgcacta cagacaatca
    10441 caaaaacacg aacgaactgc tcaactactt gagaaacagc agttggttcc atcaagaatc
    10501 ttccttggaa attccctcga taaaaagata gaccaggcat cagcaaaaag gtaaaggaaa
    10561 ctacttggat cagcggtttc aattgtatgt ctcccatcat ccaagcaatc cagctgctaa
    10621 atgcaaagac aaacaaccac aaaaagacac ctgtccaaaa tactaaggga taaagatttt
    10681 gcaaagcttg ctttcgctcg aaaggattct ttctttctgc aacgtacttt gatatgaact
    10741 gcggaagacc ggataaagct aaagtcattg ctatcccata aattggataa acttgctgat
    10801 aaacataaaa accttcgtcg ccgactaagt tttggagggg aattcggtaa agggcactta
    10861 atacttttgc tatgaaagaa gcaatcgtca atacaaatgc tccttgcatg acgcgccgca
    10921 tttctttatg atccaaatca ttgctccttc ctacgctgac agatattttt gctcacgcaa
    10981 cgctttgaca aacttttgga tttcctgaag ccatactgct tcttccattt ggttggggat
    11041 cgtcaagcgt atcaccatct gttctttttc aacgcctaga ctggctttta gttttgtcgc
    11101 tgtcagtgct tcgaataact gttccacact atagcgtttt gttccaactt tacttagagt
    11161 aaagactata tgcgcctcct gtttccttat cgtttctagg agcgctcgat cgccatccat
    11221 tttgatctgc ccaattgtca agagatgtgc tacttcttct ggatattctc caaaacggtc
    11281 gagcagatca tcttctagtt catctagcat ttcttgcgaa tcaagttcac gaattcgttt
    11341 atagatctcg attttctgcc gttgatctgc cacgtatgtt tcaggtagat acgcatcgac
    11401 accgaggtcg atctcaacag tggtcttctc cacttgacta ttctttcctt gtttacgaga
    11461 aacagcttcg cttagcattt gagaatacat atcgaaaccg actgcatcaa taaatccatg
    11521 ctgctgagca cctaagagat tacctgcacc gcgaatggaa agatcccgca tcgcaatctt
    11581 gaatccagat cccagttctg taaaatcttt gattgcctga agacgttttt cactgacttc
    11641 gttaaggatc ttctgctgct catacataaa gtaagcatat gcgacacggc tgcttcttcc
    11701 tacccgccct cgcaattggt ataacgtgga taatcccata taatcagcgt tctcaacgaa
    11761 caacgtattt gcgttcggga tatctactcc tgtttcaatg atggttgtag tgacaagaac
    11821 atcatattga ccttcaataa attcaaaaag cgtattttct aattgcgcct ctgtcatttg
    11881 cccatgagca taaccgatcc gtgcttccgg aacgagttct tggatttctt ctactttttg
    11941 ttcgatcgtt tctacccgat tatataaata gaatacttgt ccacctcgtc ccatttctcg
    12001 atggattgct tcgcgaatag ccccaggatt tttttccata acatacgttt ggatcggata
    12061 acgattcgca ggcggtgttt cgattactga aagatcccgc acgcctaaca tcgacatatg
    12121 caaagttctc ggaatcggtg ttgcagtcag agtcaaaaca tccacttgtg cacgtaactg
    12181 tttcaatcgt tccttatgtt ttacaccaaa acgttgttct tcgtcaatga tcagtagacc
    12241 caaatcgcta aattcaatat cttttgacaa aattcggtgg gttcctacaa caatatcaac
    12301 ttgacctgta cgcagttgtt cgatggtttc tttttgttgc tttcttgttc tgaaacgact
    12361 taatagcccg atatttacgg ggaaaccttc aaatctttcc agcatcgttt catagtgctg
    12421 ctgtgccaag atcgttgttg gaactaaaaa ggctacttgt ttgctttcct ttatcgcttt
    12481 aaaggccgct cgaagcgcta cttctgtttt cccataacca acatcaccta cgagtagtcg
    12541 atccattggt ttttcttttt ccatatcccg tttgatctcc gctgcacttc tcaactggtc
    12601 atcagtttca gagtagggga aggcattttc gaattctttt tggtaggcgt catcaggtcc
    12661 aaaagcatat cctttttctg actctcttgc ggcatataat ttgattagat cgtcagcgat
    12721 atcctcgatt tttgaagaga cttttcgctt ggttttcgtc cattcacttc cgcctagctt
    12781 attgatgcga ggcgctttgg cttcagaggc gacatatttt tggatcagat tcagttgagt
    12841 aacaggaata aacagtttgt cgtcgttttg atacaaaata gtcatatagt cttggtgaac
    12901 gccatctact tctagcgttt ccatcccaat gtatttcccg ataccatgat tggcatggac
    12961 aacgtaatct cctgctttta actcattata gcttttcaat cgctctgcgt ttgttactgt
    13021 ttgacgtctc gtttgttttt tcgtcgtttt ttggaaaatt tctttttctg tgatagctac
    13081 tattttttct tgaggaagtt caaaaccagc ctgcaaagct ccttcaacta attgtacctg
    13141 tcctctgatc aatgcatttt tttctgtttc tactactaat atgtcttcat ctcgaagcat
    13201 ttgttctgct ttgcgtattc tgtcctttgt cggaataaag atcacaacag tctgtttttg
    13261 cttgcgccaa cggtccattt ctgttttcag caatggcatt tgtccgaaga actgttgcat
    13321 cgtccgatat tgaaaattat ggattgcttg gaaacgaaga tttcccatcc ctttttggaa
    13381 gagtgagaaa aaggttgtgg tgaacttttc cttctgcacg attttttgta tatctgctga
    13441 aaatgtctgc tcagaaaaca cccgcaattc gctgattttt tgagtctgcc attctgccgc
    13501 ttccctttcg atttcccgat ttgtttccat gattcgctga taatcatcaa cgactagtaa
    13561 actatttgaa gggaaataat ccaagatcgt cacagattct tggtaaagaa gatctgagta
    13621 gaattttgct tcttctgtcg ggacacctgc ttgccagctt gaagtcagct gaccgaagta
    13681 atcttgcaaa aactcgcggt ctgcttcttc tgtggtcgca gcaagccgtt tttctagcat
    13741 tttttgcatt tgctctattc catgttctag atcctctggt ccgtagactt gttcactcgt
    13801 tggggaaacc cagatttctt ccgttttttc gattgagcgt tgtgtttctg cttcaaaata
    13861 ccgcatagaa tctatctcta catcaaatag ttctacacga acaggatagg ttgtcgttaa
    13921 cgggtaaata tcgataatgc ttcctcgaat actgaattct cccggttttg cgaccatctc
    13981 ttctcgtaca tagcccatca aagtcaattg gcgaggaaga ttttccacgt ctatctcatc
    14041 accaatatgc caattcaatt gcgcctgtag ccaagttttc ttattcggca gtcgtttgtg
    14101 caaagatgcg actggcaaca aatagatacc tgcttttttt tcttgaagtg cgttaagcgt
    14161 tgcaactctc tcgcctcgcg cttctggaga agaaaaggcc atttcagcag aaagcacttc
    14221 atccactgga aataaatgga tctgatcttg cggaatcaca tgttgcagat cttctgctaa
    14281 ctgattcgca taatacaaat ttggcatcag aataatcatg tttttatttg ttttcttaaa
    14341 cgctcgagca aatagaagtg ttttcgctga gcccgctaat cctgtgatta gttgtctagg
    14401 cattttttct tctaaattgc tgacccattc ttttacttgc ggatcttttc cgactaattg
    14461 aataatatcc attccttttc ctccttcctc aattgaatcg attcatcgca tccacgaacg
    14521 aatgcccttc tatgagatat tcgactgctt taacagattg acacatgctt tcttctatca
    14581 aaggctgatt ttctttgctg aaaggactaa gcacatgctg gactactgtt tttttccctt
    14641 ctggcctgcc gattcccacc ttgattcgat caaagacatt cgtattcaaa tgggaaataa
    14701 tacttttgat accgttatgc ccgccggcac ttcccttttg acggagccgg atttttccca
    14761 ctgccagatc caaatcatcg tagattacga ctaattcctc tggataaatc ccaaaataag
    14821 tcattagtgg gccgactgca cgaccagatt cattcatgaa tgtttgtggt ttgactaaaa
    14881 ggatcttttc tccattatga aaaaattcgg caacttctgc ttcgaacgga ttttttttga
    14941 aagtagcttg atgctcgcgt gcaattttat ccacgaccat aaagccgata ttgtgttttg
    15001 tatattggta tttggtacct gggtttccta acccgacgat cattttcatt tttgttttcc
    15061 acctaattct aaaaagcagc acaaaaggct ggactgctaa ttagcggtcc agtccatcga
    15121 gcttttttct tttttatact tgtcaatgca tagtataaca caaaacaagg cgtttcggct
    15181 aaaagagaat cgttaataaa tgataaagaa attaaaaatt tcttcaaagt ttaatgaaat
    15241 aattgatata taaaaatagt gaaataacgc acatgtaagc ttttacatat aatacaacct
    15301 tgttatctgt tatattttat agccaaatag cgtgacatgg ggcttgagaa atgttagcat
    15361 aagcatggga aaaaacaaat caatggaagg attgatacta aatgactgca gctgcagaaa
    15421 aaaaagatca tcaaaaagtt attcttgttg gagacggcgc cgtaggttct agctatgcct
    15481 ttgctctagt tactcaaaat atcgctcaag aagtaggtat tgtggatatc aatactgcta
    15541 aaactgaagg agacgcaatt gacttgtctc acgctttggc atttacttca cctaaaaaaa
    15601 tctattctgc tacttacgca gacgcacatg atgctgactt agttgttatt acagctggcg
    15661 caccacaaaa accaggtgaa actcgtttag acttagtaaa caaaaaccta aaaatcaacc
    15721 gcgatgttgt cacacaaatc gttgaatcag gatttaacgg tatcttttta gttgccgcta
    15781 acccagtaga tattttgact tactcaactt ggaaattctc aggtttccct aaagaacgcg
    15841 taatcggttc aggtacctct cttgactcag ctcgtttccg tcaagcactt gcggaattag
    15901 ttgacgttga tgcacgtaac gtccatgctt acatcttagg tgaacacgga gattcagaat
    15961 tcccagtttg gtcacatgca aatgttgccg gcttgcaaat ctatgaatgg gtaaaaaaca
    16021 acccagaaat cgatgaagaa gctatggtta acctattctt tggcgtacgt gacgctgctt
    16081 acacaattat cgagaaaaaa ggcgctactt tctatggtat cgcagtagca ttagcacgta
    16141 tcactcgtgc catcttagat gatgaaaatg ctgttcttcc tttatcagta ttcatgaatg
    16201 gcgaatatgg attgaacgac atctacattg gtgcacctgc tgttatcaac cgtcaaggta
    16261 tccaaaaagt aatcgaaatt cctttaagtg acagcgagca agaccgtatg gctgcttctg
    16321 ctaagcaatt aaaagaaatt ctagatgaag cttttgctaa actagacgct gaataatctt
    16381 tgaacatgac ggaaaacatc tattcggtgt tttccgtttt tttattttat cacccttatg
    16441 gtttctaaat tttttcataa agtagagata accttcgtct tttcctctaa attatgctat
    16501 catgagaccg ttccacccta aacttttact taaggagttg tcgatatgac aagatcttcg
    16561 catcgaaaaa aatcgaaaca tgttgctttg ctttcagttc ttggtgttct cttagtgctg
    16621 atcagctttt atacctatcg cagtacatac tacacaaagc attttttgcc gaatacagaa
    16681 ataaatggaa taaatgtcag caatctaaca gtcgaaaaag caaatgaaaa attaaaagaa
    16741 gcttattctg ataaaaaact ggctattaaa gaagatggaa aagtctggca ggaagtacca
    16801 aaatccgagc tcggctacaa agatgatttc acttcggagc tttctccgat cctaaatgaa
    16861 caaaacggat ggacttgggg aatgacttat gtctcagcgg cagaaaaaca agaaatagat
    16921 cctgtcagtc aaaaccacca aaaactagac actaccgttc agacattgac aactaagctg
    16981 actgatttga acaaagaccg gacacctact actgatgcaa cgatcgaaaa agcaggtgac
    17041 tctttcgtta tcaagcctga agtcaatgga aatacgatcg acgtcgatgc tgcggtcaaa
    17101 caattaaaaa gtgcggtaaa ctctggtaaa gatacaattg aattgactga attcaaagaa
    17161 aaaccaaaag taacatctga agacagctca ctgaaagaac aactcgcatc catgaatgct
    17221 atcgcaaatg taaaagctac ttacagtata aacggtgaga ctttccagat cccatcaagt
    17281 gatattatga gttggctgac ctacaatgat ggaaaagtcg atttagatac agaacaagta
    17341 cgtcaatatg taacagattt aggcacaaag tataacacaa gtacgaatga cacaaaattt
    17401 aaaagtacaa aaagaggaga agttacggtc ccagttggca cttacagttg gacgatccaa
    17461 acagacagtg agacagaagc attgaaaaaa gcgattctgg caggccaaga ttttactcgt
    17521 tcacccattg tgcaaggtgg cacaaccgct gatcatccat tgatcgaaga tacgtatatc
    17581 gaagttgatc tggagaacca gcatatgtgg tattacaaag acggaaaagt ggcccttgaa
    17641 acagatatcg tttccggaaa gccaactaca cctacacctg ctggagtctt ctatgtttgg
    17701 aataaagaag aagatgcaac tttaaaagga acaaatgacg atggaacacc ttacgagagt
    17761 ccggtaaact actggatgcc gattgactgg acaggtgttg gtatccacga ttcagactgg
    17821 caacctgaat acggtggaga cttatggaaa acccgcggtt cacacggctg catcaacacc
    17881 ccaccaagtg taatgaagga attattcggg atggtcgaaa aaggaacgcc tgtattggtc
    17941 ttctaacaaa aataatatat aaaaagaaag cacccgtacg attggtacag gtgctttctt
    18001 tttattatct aacaatgtgc tacttacatt tcagcagcag taaagacttc tgaaacatca
    18061 tcatcgtctt ctagcttatc tactagacgt tccaattgct ctttttgttc ctcatttaaa
    18121 tcaatcgtcg tttgtggaat catcgtcaat tctgcttgcg ccaaagtgaa ctctttttcc
    18181 aactcatctc gtacagcagc aaaatcttct ggtgcagtat aaatctcgaa tacttcagga
    18241 gaagtttgca gatcttctgc ccccgcctct aatacatcct caaacatcgt ctcttcatca
    18301 acagtcaacc catcgcgttc aatagcgata tatcctttgc ggtcaaacaa gtaactgact
    18361 gaacccgttt ctcccagtga tccaccgttt cgagtaaaag ctactcggac atttgtcgct
    18421 gtccgattac ggttatctgt caatgcatgg actaagattc ctactccacc cggaccatat
    18481 ccttcatacg tgatttcatc gtaattcgtt tcatctacgg cactcgtagc ctttttaatc
    18541 gcccgttcca cattgtcgtt aggcatattt gcagcttttg ctttgtccac aacaagccgc
    18601 aaagctggat tcatagatgg atcaggaccg cctgctttag ctgccatata aatttcacga
    18661 gaaagtttct gaaagacttt ccctcgtttt gcatcttggg cattttttct tccttggata
    18721 ttatgccatt tactatgtcc tgacatgatt tttcctccct tgttcttttg agaatacact
    18781 tctattctag tactatttca caaaaaaaca aagccacagc caatctataa acgcttcttg
    18841 aatgccgcaa aaagcacaca taatatcaca gcagtcagag caccgatcga atccaacatg
    18901 acatcttgga acataggtgt tcgtccaccg gtcatcatct gatggaattc gtccaaacct
    18961 gcgtaccctg ttgctgaaag ccaagcaagg atcgctgtca gccaccaaat ttttagcttg
    19021 gggaaaacac ctaaaaacaa gctgcctccc aaaataaaat aggtaccgaa atgtgcgccc
    19081 ttccttaaaa agaactctaa aaatttggcg tagcccagat ggtcgatact caccatactt
    19141 ccaccataat taaaacgtat acccgctaat gtgtctttaa atggctgatt aggcagccag
    19201 ctttctaatc gcgaaacttg tgattgctgt ccgtaagttt gagaagaact gtaaaataag
    19261 attataacga ctatcagtgc gattactaaa taaatatttc cgtttttcat ttgttttttt
    19321 gaagaattca taagtcacct ctgtatttta tcttagactt tttttgaaga aacaacaatc
    19381 attttcatag agacttcttc cataaaaaag tgctatactt aattttgtat tacaatatga
    19441 agggagtttt ttcatgagtt attcattaaa ttggaatcta gattctattt tttccggagg
    19501 cagtcattct gatgctttga accaacggat gaagcaattg gaagaccaaa tgaacgagta
    19561 ttatcaccgc gtaacaaaat ggtcacctag ttctgacaat gcagagcagt taaacgctat
    19621 tcttcaattg caagaaacga ttacgaatgg ttttacccaa tgcagcagct atattactgc
    19681 attgctttct gccaatgtca atgattcaga tgcaaaggtc ttatcaggca agctttacgc
    19741 aatgctgcct cgtctgcaat cagccgaaac tgtattgtca aagaaatttg cagaaatatc
    19801 tgacaatgat tggaatcaga tgctttctca atcttcgttt gaaacaattg cttttcgttt
    19861 aaacgagatt cgtcgtgatg gctcacaatt attatcagaa gctgaagaaa acattataaa
    19921 tacgctttct ttagatggtc taaatgcttg gagcagtcat tatgatacga ttgtagccag
    19981 catttcgatt cccttcgaac aagatggaca agtagtcgaa ttatctgctg gacaagcctt
    20041 caataagatg atgggcgatc cagatccaaa agtcagagaa acacttttcg cagcatggga
    20101 agaagcctgg aaagaaaagg cacccctctt cacggatact ttgaatcatt tagatggttt
    20161 tagactttct gactatgaac ttcatggtgt cacagatttt ctacaaaaac cattagagta
    20221 caatcggttg aagaaagaaa cattgtctgt catgtgggat acaatccaga aaaacaaaca
    20281 accccttgtt aattacttga ctagaaaagc taatcttttc ggtaaagaaa aaatggaatg
    20341 gcaagatcaa gatgcaccta ttattttagg cgatttgaaa gaaaaaacct ttagttttga
    20401 cgaagcagca gcatttatta tcgaaaactt taacaaattc agtccaaaaa tggctaaatt
    20461 tgcccaatct gcttttgaaa agagctggat cgaagcagaa gatcgtcctg ggaaacgtcc
    20521 tggtggttat tgtactgagt taccagaaac aaaagaatca aggatcttta tgacctacag
    20581 taattctgtt aatgaggttg cgacacttgc tcatgaacta ggacatgctt tccatagcag
    20641 cacgatgtgg gatttacctt ctttaaatcg cgaatatgcc atgaatgtcg cagaaacagc
    20701 aagtacattc gcagaactga tcgtagccga tgctacatta aaagtcgcaa aaacaaaaga
    20761 agaaaaaatc aatttgctag atacaaaact gcaaaatgct ttagctatgt tcatgaatat
    20821 ccattcccga ttcatttttg aaaatcgatt ctatgaagca cggcaagaag gattagtctc
    20881 agaagataag atcacagaga tgatggttga ggcgcaaaaa gaaggctatc aaggagcttt
    20941 agctacttac catccatatt tctgggctgc aaaattgcat ttctttattg atgacgtacc
    21001 gttttataac ttcccataca catttggcta cctctttagt ttgggcatct atgcttacgc
    21061 caaccaaaag ggagcaaatt ttgaagaaga atatatccat ttactacgcg atactgcctc
    21121 aatgacgacg gaagatcttg cgaagaaaca tttgaatgtc gatcttaccc aaccagattt
    21181 ttggcaagca ggtatcgaca tggtgactga agatatccaa acgttcatgg aattgacaga
    21241 agaatttatc tgatttctat tttatcacaa taaaaaaaga gttagtccag aatgggctaa
    21301 ctctttttga ttaatcattc ttacatgctg acagcaaagt caggggcaaa ccattgaact
    21361 gaaccaactt ttacgctttc gcctggttga ggagcatgga tatattgtcc tccgcctaaa
    21421 gcaatcgcta cgtggtaagt tccgccttgt gacccccaga ataacaagtc tccagctttt
    21481 gcttgagaaa ctgaaatttt tgttccagct gattcttgag gaactgtcca accaccgatg
    21541 tcacgaccag ttacttgcat gtaaacatag cgtgtgaacc ctgagcagtc aaagccactt
    21601 ggatctttac cgccccaaac atatggagta ccaatatatt tgtaagcttc tgctacgatt
    21661 gctgcaccat tcacacttcc agaaggagct ggagcaggtg ttacaggttt tggttgttca
    21721 ggtgttggtg ttggcgttgg agccggagta ctacttcctg tgccgtttcc tgtatcaaca
    21781 ctttgatctg ttgatggtgt tgtaggcgca ggtgttgttg attcttctgt tgttgaagat
    21841 tcaggcactg ttgttgattc ttctgttgct gaagattcag gcactgttgt tgattcttct
    21901 gttgctgaag attcaggcgc tgttgttgat tcttctgttg ctgaagattc aggcgctgtt
    21961 gattcttctg ttgaagattc aggtgttgtt gattcttctg ttgctgaaga ttgtgtagct
    22021 gatgatgatt cttcagtcat tgaagattgt gtagctgatg attcttctgt tgctgagctt
    22081 tgtgcagtag atgaagcttg agtagcttgt gcttcagcct ctgcttgttc gcgtgcttct
    22141 ttttcagctt tttcttgtgc agcttgttga cgagcttgtt ctgctagacg ttgttgttca
    22201 cgaatacgag cttgctctgc ttcagcttct gctttttgac ggttcaagtc agctttcttg
    22261 tcttcagcag ttgcttgttc agcagctaat gaagttttca gtacgttcaa atcagcttgt
    22321 ttagataaaa gatcgccttt ttgagattcc aaagcagctt ggttttcagc taattctttt
    22381 agtttagcat cgttttcagc ttttttgtct tctacagctt ttttatcttg tttttgttgt
    22441 tccatcaagt cgttgtttgc ttttaccatc gttgtcattg cttgaacgcg tccaatagca
    22501 tctgctaatg aatcagcatt caatacagca tcgatgtagt ttgagcttgt gttgcttact
    22561 tgtgcttcgc gtgcttgttt ttggattgta tcttcacgtt tttcaatacg ttcttgtaaa
    22621 tctgcaatgt cttttactaa ttgtgcagat tcttgacgca atgtatcttg ttttgctaat
    22681 aggtcttgtg cttgtgtgtt gatttcagaa acttggcttt ctaaggcatc gatttgtgat
    22741 tgtgcatctg cttgttgatt tttcaagtct gcaatctttt gatcttgctg ttgtatctga
    22801 gaatcaaaat cgtccgccgc ggcagcgatc ggtgatgcta cggcagtcaa ggtcattgaa
    22861 cataccatta ctgctgatat taaactcttt ttcactcttc attcctccga ctggcttaat
    22921 ttaataaata tctaaatata tttaagtctt tcttaacgat ataaaaattg taccatagca
    22981 gtgtgtcaac gatataatag ttatgttaca aaaatgtttc aaaacaactt ttaaaaatga
    23041 caaaactgtt cgtttcagaa aatgatcatg aaaaagccgc gttaagtcta gcatttctta
    23101 agataacaac gattcttttt cgctttcgac ctaaaaataa aaaaagaaat tattcatcac
    23161 tgaataattt cttaaaggga aaaatgaata atacaaatat aatcatgttc aacagcagtg
    23221 taggtcctaa aaaccttgta ataaaatacg tgttatttac tactgctaat ttaaaaatca
    23281 actggaccac catcgtaaac aattcataac ccgtgacaaa gatgatcata ctgaaaaatt
    23341 cagtaaagat gttgacatgg ataacgtctt tcattacata catcaaccat acaattaaag
    23401 ggagagctac tgcatagata ccgataacgc caatatagta agcgtcatag atagccccga
    23461 gaacaatcgt ggtaatcagt aaataacgtt tttcaaacgc catactgcaa cataataatg
    23521 ccaatatcag aaagtgggca tttgacatat aggtgccttt cgaccactcc cctagcattc
    23581 ttgttaaatg accatctatc aacatcaaaa agaacaaaac gattggcaga tagtacttca
    23641 ttgtttcttt cttcaacatg gactaatcct ccgctagccg ttggacaatc gtcacaactg
    23701 acacgtcata catttctgca taaggtttca cataaacttc ccgatccagc ccataactat
    23761 ctggtttcgt tttaataacc gtaccgatcg gcaagttagc tggagaattc cctccaagac
    23821 cggatgtctg gacaacatcc ccttctttga tatccgtatc accagttaat tgggtcacca
    23881 ctaaggcatg gagcttttca tcatagtttt taagcaaacc aaacgcttcg ccattagccg
    23941 aagatacccg tactggaaaa tgattggagc tttcattaga ggatgacagt aattcgattt
    24001 tagacgaagc cgtattgacc tcgatcactc ggccaatcaa tcctttttgc gacatgactg
    24061 ccatatttgc ttcgataccg tctttagaac ccttgtctac gatcagcatg tcctgccaac
    24121 tgtcaggcga acgagtaatg acatttgccg ttactttttc gtaactagtc agcgtctgat
    24181 tcaactcaag ttcttttttc aacgcttcga tttctctctc gtaattcttg ttttgctgtg
    24241 aaacgtcatc atagctatcg attttttctt ttagccgctc attttcggca taagttgaaa
    24301 aaagattatg gacagaatct actccatttc gtacccaccg tactggggca gagattgttt
    24361 tatcaaccat tgcaacactg tcattaacga tggattggaa gaaattgggc tttccttcat
    24421 tcgctcgctg cgcagcggtc acacttagta tcgtcaccac gatgataaca ataaccaagg
    24481 taataataat atttttatta ggattgaact tcttcacaaa gacacctcga attaattaga
    24541 ctcttgtgtt caattttatc actaaatgcc gtgaaacaaa aggtaagttg ctcctcttaa
    24601 gctttttttt agcaaataat agattctgtc atttttagcc tgaaagacaa atttttttat
    24661 ttgtttatgg atcaatcttt gctttgaata actgcaatca taccatctga aaaagaaaat
    24721 tctgcggtat ctgaaagaaa ttcgttactt gcataagatg tcggatattc tacttcttta
    24781 ttttccaata catacttgct gccttttaat gtaagattcg agacgggagt caagcagcaa
    24841 taagctaaat acttcatatc tggtatctgt cttactatat gctctccagg caaataataa
    24901 gacaaataat tttgacaatc tctgataata agctgatggg caaagggttt gaagcgaggt
    24961 tccataccta accagagatt ggctaaaaga tgatccaatc ttccgcccgt agctccaatc
    25021 aaagtgactt ccgcttgcgg gtaacgttca aatgttttta agatacctaa ctgtgtatct
    25081 gtatcgtctt tttctgcagg ggaacgggta tactctttgg cttttgcaaa tacttccttc
    25141 tgctcttcgt tcgacaatga atcaaaatcg cccactgcca gatctactgg gtagcctgct
    25201 tgaagcaggt acagcgcacc acggtctatc ccgacatagg catcgtattt ggacagcaga
    25261 gactgcggcc agttttgcgg attacctcca gcagctaata aaattttcat ttagtctaat
    25321 gcctctttta atcgttcgat ttgtccgact ggattttcgg ctccatagat atatgatcct
    25381 gcaacgaaga catccgcccc tgcatcttta cagatttttg ctgtttctgg aacgattccg
    25441 ccatctactt cgattgcata agtccaattg ttctctctac gtagatcagc gagttccgta
    25501 attttttcta ctgtttcttc aataaagctt tgtccgccga acccaggatt gacagtcatg
    25561 actagtactt gatcagccaa aggcaaaaca tgtttgatca tggagactgg tgttcctgga
    25621 ttgataacta ctccagcttt aactcctaag ctttttgtca tttgaagtgc ccgatgaata
    25681 tgaggagttg cttcgacgtg gacagtaatg atatctgctc cagcttttgc aaatgctgga
    25741 atgtagtttt ctggatcaac gatcatcaga tggacgtcta acggtaattt agtaacagga
    25801 cggattgcct gaacaatatt tggccctaat gtgatatttg ggacaaattg gccatccatt
    25861 acatctacgt ggatgtaatc tgcgcctcct ttttccacta actcaatgtc tctttgtaaa
    25921 ttggcaaaat ctgcactcaa aatggatggt gctatcttca ttcttgtttc ctcctatttt
    25981 cgtttacctt ctttttttgc atacattggt tttctttttt cgatttcttg taagaattgc
    26041 aaataattgt cgtaacgtgt ctgtgcgata ccacctgttt ctactctatg ttttacttcg
    26101 cagccaggtt ctttagcatg catgcactct ctaaatttgc aatggacaga agcttctaca
    26161 aattcaggaa attgtctcgg cagttctcct gcttcaattg tcaaaaagtc aatcgagcta
    26221 aatcctggtg tatctgctac taacccgcca tagataggaa tcagttccac atgacgtgtt
    26281 gtatgccgtc ctcttccaag tgcatcagaa atctctcctg ttgctaaatt cagttccggt
    26341 gatatttgat tcagtagcgt cgattttcct gctccagact gacccataaa gaccgatagc
    26401 cgttctggga agtaacggat cagttctgtc gtatcacccg tatgattggg tacaatcacc
    26461 ggatagccta ttttagtata ggtttgcttg atctcttcga ttttttctgg gtcgtctgac
    26521 aagtcggtct ttgtcaaaaa aataatcggt tcgatcgact cgtattccaa ggtaactaga
    26581 aagcggtcaa gtagattata agaaaatgca ggctctacga tacttgtgac aatgattcca
    26641 agatcaacat ttgtgactgg tgggcgaact aattgatttt ttctcggcaa gatttccaga
    26701 agatagccgt ctgtttgatt ttcactctca aagatcacct gatctccgac aagcggcgtg
    26761 attttccgat tccggaaatt tcctcttcct cttgtttgat aggtctctcc gtttgcgtat
    26821 acatagtaaa aaccgctgat tgcttttctg atttgtcctt tgataagtgc cacctccgtt
    26881 tttgtttatt ttaccatacg aagaggaaag taggtgttat tccatgcaaa cttctcaaag
    26941 tatatggctt gaaaattgat caaaagagat agaaacacaa aaaagagaat gcaacaaatc
    27001 aatgtcgcat tcccttctga tatattttat tcagcactta ttttgaactt tctgaggtgc
    27061 tagctgatga acttgtggag ctggaagatt cttcttttga agagttgctt gtgctactgg
    27121 agctacttga gctgctagaa ctgtctgaag agtctttttc agaactagaa gacgctggat
    27181 ctggtccttt agagtaaatt acgttcacaa ccattccttt ggtaattgtc gttcctgccc
    27241 ctggtactgt acgaatcact ttatctttat ccaccgtgtt tgaatattcg gaagtctcat
    27301 gcccgatata ttctgcaccg acactagcta aataactttg tgcttcgctt tttgtatagc
    27361 cggagatatc attcaattta ggctctgttc cttggcttac gacaaaattg atgtaagttt
    27421 cttctgctac aacttcaccc gaggctggat cctgactgat gatcgaacct gatggtacag
    27481 tgtcgctata gtcataagta gcactaatat tattgatatt gaatccttgt gtaacaagcc
    27541 aattacgaac agtttcgtag ttttctccta catgactact caaagtcact gtttctggtc
    27601 ctttgctgac tgtgaaagta atcgtgtctg ttttaggatc gacttctgta tcttctgatg
    27661 gagattgcga aatgatcatt ccgctttcta cctctgaact gaattcctct tctttttgaa
    27721 tcaagtcagc agaaaaccct aattctttca aacttgcttc ggcatcttca taacttttac
    27781 cactgtaatc atctaatttg atttttttcg tgccgctact aatatacaga gtgacttcgc
    27841 gtttttgctt gactgtcgtt cccgctgccg ggtctgtctt cactacatta ccttcttcga
    27901 ttttgtcatc tgcaatttct tctgtttttg ttgctacttc taatttcgct tttgcgagtg
    27961 tttctctagc agaagcttca gaaagatcag aaacatcagg aacaacaact tctcctcgcc
    28021 cgccagaagc aaagaataca gctgttccga ttcctaaaac agcaagaata gctaatagga
    28081 tcagccacca ttttttctgt cctttctttt taggatcagg cagaacttct tcctcctctg
    28141 gcaaggtttc gttttctggc ttgtcttttg gcagaggcat agatttgaat gaatcaggca
    28201 ttggtgcatc ttccgtaagg ggtgtgataa cttttgtttc attatccatc acatgaggct
    28261 gccatttttc ttcgtttgca cgagctggtg ataatactgt agaaagatca tcagacattt
    28321 cctcggctga cttataacgg tctgcaggtt ctttagccgt tgcccgtaaa atcacgtttt
    28381 ccagtgcttg tggcacattt ggatcaagtg cttttataga tggaagatca tcttgaaaat
    28441 gttttaaagc aattgttaca gcagattcac catcaaacgg tacgctaccc gtcaacatct
    28501 cataaaggat gatccctaaa gcataaatat ctgactgctt cgttgccata cttcctctgg
    28561 cctgctcagg ggacagataa tgaacagatc ccagcatcgt attcgtctgc gtgatcgatg
    28621 tttcagataa agcgatagca atcccgaaat ccgtgatttt tacaacacct tcattatcga
    28681 tcagtacgtt ttggggtttc aaatctcggt ggatgatttg atggttatga gctaaagaaa
    28741 tagcagaaag gatctgctgc ataatattta ctgctgtttc ataaggaaca ggataatgtg
    28801 tttggatata tcgtttcaag tccattcctt tgacgtattc catcaccaga tactgcatgt
    28861 tgtcttcttc accaacatcg taaacactaa caatgtttgg atgaacgagt tctgttgctg
    28921 ctaaagcttc tctctgaaat cgtcgaatcg cagtctggtc attttgaaag tcaaatcgta
    28981 agactttaac tgctacatca cgatccaaga ttaaatcgtg cgccaaaaat acatttgcca
    29041 taccaccgct accgatattt ccagtgattt gataacggcc atttaatttt ttgcccaact
    29101 cgatcataca ctgtcctcct tatattcgat aagaagaacg gtgatattat ccgctccgcc
    29161 tgcttcattg gcacgatcaa tcagctcagt tactttatga gacaatgggc cttcttgatt
    29221 gatgatcgtt cctatttctt cttcagacag catgttcgtc aagccatctg aacataacag
    29281 cagtcgatct tttagttgcc aaagatgagt agaaacatct acttcgactg ttccaggcat
    29341 gccgacagaa cgtgttaaaa tatttttcct tggatggttc actgccattt cttcgctgat
    29401 ttctcctgat ttgactagtt cattgactaa agaatgatcc tccgtcaatt gcatgatttt
    29461 atcttcacga atcaaataag ctctgctatc cccaacattg gcaatcgtga accagtcatc
    29521 tgacagagcg gccgctacga ttgttgttcc cataccgtta tattccggct gttcttgtcc
    29581 acgctgataa atcagcatat tttcttcttg aatcgattga atgaaccatt gggcgatttt
    29641 ttcatcgtca acagcttctt gtttttccca agcttcgcct agattcgtta ccgccatctg
    29701 actggcaatg tctccggcac gatgaccacc catcccgtct gctaatacag caagcttgag
    29761 acctgaacgg ctggtaaata cactggcata gtcttgattt gtgttacgtc gtcttcctac
    29821 atctgattga tattcaatct gcattttttc acctcattac tttttgcgca aacaacaaat
    29881 gaaaaatcca tctgtgtaaa actgatgcgg atacaaagtc aacattttct cttcgattga
    29941 tgattgtagc ataggattgg tcaaaacatc aatcctctca aaatcagggt gtctttccaa
    30001 gaaagcagaa acaacgtctt ggttttcttc ttttaagatc gtacaagtgc tataagtcag
    30061 aataccggaa gactttaaag ttggtgcgca gctttctaaa atttccaatt ggatttttgg
    30121 taaattcgct aattcatccg gctgtttttt ataacgaata tctggttttc gccgaagcag
    30181 cccaagacct gaacaaggcg cgtctactaa aatccgatca aactgctctg cttcgaactg
    30241 tttactgact tctctagcat ccatcttttg agcgtagaca gcagaagaga cacctagacg
    30301 tgctgcatta tcttcaatga gtttgacttt gtgttcgtgt acatctaaag cgaccacttc
    30361 tccaccgcat gacggatcta aaaaagaagc aatatgcgtc gtcttacctc cgggtgctgc
    30421 acaggcatct aagacatgat gttcaggctc gatttgcata gacggcgcta caagcatcga
    30481 actttcatct tggatcgtca tgacgccatc gtggaacaat gagctagaag ctaaatgccc
    30541 ttttttcgct actataccgt atggactgac ttggcttttt tcagctgtga tctcttcttc
    30601 ttgcaaaaca gtgatggcct gatctctgga aagtcggcgt gtatctactc gggcactagc
    30661 atggctaggc tgatatagcg ataaaccgag cttttcagtt tcttcgtatc cgatttgatc
    30721 caccagtcgt ttcgtcatcc atagaggcag gctgattttg acagaaagtc tttcgatagg
    30781 atcagcaatg ccttgcagat ctggtgctcc ttgacgctga taattcctca agacaccatt
    30841 tacaaatttc cctgtcccag gatttccttt tacttttgcg atttcgaccg cctcgtttaa
    30901 aatagcatgt gcagggactt tatctaaaaa ttctaattgg tatacagaaa gataaagaag
    30961 cgtcttgacc cagtcatcca ctttttttgc tttagcgatc aatggtgcaa cgtaaaattc
    31021 caatagtcgc tgatggctaa tcgtaccata gatcaattct gtaaataaac ccacatcttt
    31081 ttgatttagc tcgctttgtt tgatcatctc attcaacaaa agattcgagt aggcgccacc
    31141 cttgttcact cgctctaatg tcagtaatgc catatatcgt actgattttt tcattttttt
    31201 agggattttt ttcattattt cacctgctga ccaatctgaa cttgctgacc gcttccgtta
    31261 aggaaatcat gtacggcctg ttttccttta ccagctggct gtaattcatt gatggctaag
    31321 acggtctgtt taccgcaagc aatccataga ttttttttgt ctttccggat gatcgtacca
    31381 ggtgctttgt ctgtagtttc tgccaatact tcaaccgata ataatttcca gcgtatgccc
    31441 tcataggtcg tgaatgcaat tggccaagga cgcattccgc gtacttggtt gtcaatttct
    31501 tctgcagttt tatgccaatc gattgcttct tgttcccgtg tgatgtttgg cgaaaaagtt
    31561 gcttctgact cgtcttgagg tactggtttt tgtccatcca aaatattggg caatgtttct
    31621 agcaatagct ttcttcctaa aaggctaagc ttttcaaaca tcgtccctac atcatcttgt
    31681 ttagtgattg gtatgctttc ttgcgcatag attccgcctg catccatttt tttgatcatt
    31741 tccatgatcg ttacaccagt ttctttctcc ccattcatga tggcataatg aacaggcgca
    31801 cctccccgat atttaggaag taaagaagca tggacattga ttgcccctaa ttttggtact
    31861 tgcaataact tttcaggcaa gaattggcca aatgccgcag tgacgatcac atcaggcacc
    31921 aattcaatga tttcttccat ttctggcgaa ccggagattt tctctggctg cagcacacgg
    31981 ataccgtgct tcagagccgc ttcttttacc ggtgtcggcg taattactcg tttccgccca
    32041 actggacggt cgggctgtgt taccactgcc tggatctcgt aacctgattc tatcagccct
    32101 tcaagaatcg gcacagaaaa agcaggtgtg cccataaata ctagcttagt catcaagatg
    32161 ttcctccata tattcttcaa gttcttcttc cgggatctgc tgtatcattt tctcaatgaa
    32221 caagataccg tctaagtgat cgatttcatg ctggaaggca cgggctaaat agccaaaagc
    32281 cgtcacttct atctcttctc cgtctcgatc ataataacgc acggtcactt catctgctcg
    32341 cttgaccgtt ccatagacat gcggaatact gagacaacct tctacgtcaa ggctttcacc
    32401 ttttgcttcg atgatttctg ggttaatcag ttcaaatttc tcgccttcat ctacttcgat
    32461 cacagcaatt ctcttgtttt gtcctacttg aggagcagcg atccctattc cgtcattcgc
    32521 aatcattgtc tcatataaat tgtctaataa agcgattgtc tcgtccgtga ttacatcgat
    32581 tggctgagca gttcttttta atttatcatt agggtggatc aatataggat agcgcataat
    32641 ttggcccttt cttaaataaa gtttaatggt tcgttgtcaa ttgccacaaa aagaccttgt
    32701 cgctgttctt tctggcttcc attcaaaatt tcatccaaaa catgaggaag attcggttca
    32761 tgtttatatt tgatgattag ttgataataa tatcggtttt tcactctcaa aatcatgctg
    32821 ggcgttggcc ctaatagcaa gctttgaggg cttaacactt cttttagctg attggcaatc
    32881 tgaaagattt tctttgccgc tacttgttct tcaggatggc tggcggttat tttcacagta
    32941 aagtaataag gaggatagcc tccacgatgc cgtacatgca tttcctgctg ataaaactgc
    33001 tcataatttt gttttttagc taattctatg gcgtaatgtt gaggattgaa tgtttggatc
    33061 acgacttcgc ctgctttttc cgctcgccct gctcgtcctg aaacttgggt aagcaattgg
    33121 aatgtatgct cactagaacg aaaatccggt aaattcaggg aggtatcagc attcaacacc
    33181 ccaactaatg tcacttctgg aaagtccaaa cctttagcaa tcatttgtgt ccctaataat
    33241 atatctgctt cttttgcacc gaatttttgt aaaatctgtt cgtgtgcccc ttttcttcga
    33301 gtggtatcta catccatacg caaaatccta gcttgcggat aaagttctcg gagttcctct
    33361 tctacttttt gagtacctgt tccatagtag cggattttat tgccgccaca attaggacag
    33421 cgattgggaa taggttcttc atgtccgcaa taatggcagc gcattgaacg tgtatccata
    33481 tgcagtgtaa gagagatatc gcaattagga catggaagaa caaatccaca gtccctacac
    33541 atcacaaaag acgaatatcc tcgacgattg agcagtagga cagtttgttc ttttttgtct
    33601 aatcgatttt gtattttttc ctgcaaatta gcagaaaaag tagaggtccg atgattctga
    33661 aactcttcac gcatatctac gatctcaata gctggaagct gtgcagctgc tttggctcgg
    33721 tggtttaact gcaataactg ataaacgcct ttttgagctc gtgctcttga ttctaaagag
    33781 ggcgtcgcgc ttcctagaac tattgggcaa tgatgatatt tactgcgcca aattgctaga
    33841 tctctcgcat gataacgcgg tgtctcatct tgtttgtaac ttgattcatg ttcttcatcg
    33901 ataatgatca gcccgatatt tttcagcggg gcaaaaatag cagatcgtgc gcctactact
    33961 acttgcgctt cttcccgctc aatcttgcgc cattcatcat atttttcacc ttgggaaagt
    34021 ccgctatgta agaccgcaac tgattctccg aagcgtcctt tgaatcgctc gaccatttgc
    34081 ggagtcaatg cgatttcagg cactaacata atagccgttt tattttctga caaaacatca
    34141 gcgattgcct gaagatatac ttctgttttc ccgctgccag tgattccctc cagcaaaaag
    34201 acctgatctt tttgctgctg acctgctgtg atgatttgtt cgacagcatt tttttgttct
    34261 gcattcagtt ccaatgccgt cgtttggtca aatactcggt ctttataagg gtcgcgataa
    34321 cgttctgatt ctataaactc cagccagccc ttttcttttc cttgattcaa gacagcagta
    34381 ctgattcctt tatttttgaa ataagcaatt ggttcttctt ggctcagttc agataaacac
    34441 aaaagaagtt ctttttgttt cttggcattt tgccgtaatt ttgcccattc ttcttcgatt
    34501 tgcttttcag ttaacaaaga acggaccaaa cgaatcgttt ttactttatt tcgtgtatgg
    34561 acttcatatt tgatatctac taattgctct tggcgccagc gaatcaattg agaaaggctg
    34621 ccttcttctt ctgcttcctt ccaggaaatc acttctcgct gatcaaacaa tacctgaact
    34681 tctggtgtgt ctgccaaagg atagatcaat ttatcatatt ctgctttcat cacactcgga
    34741 agcatcgttt gtagacaagt gattttgaat gcgtaagtaa tttttttcat ataatcagct
    34801 aatgaaagta attcttcatt gaccaccgga gcaaggtcta gcaaacgaat aactgccttc
    34861 aaagatggat tagctgattc ttctgatttt tggatagcca taacaaatcc ttggacatga
    34921 cgattgccat taccaaaagg gacttctact cgcatcccga cttgcaaagc tgtttccatt
    34981 tcagagggaa ccaaataagt gaatggctga tcggtctgca tagtaggtac gtccacaatg
    35041 acttcagctg ttaatgtcat ggttcgtttc ctcctttttt tgtcttttct tatcaagcga
    35101 caaaaagttc cttgcctatt ttactagaga tcgatggatt tgtcttatct tctgccaaat
    35161 cctaacaaaa aattaacagc agataagaaa aaaaagaact gtgtcaaaaa gttcagacac
    35221 agccttttct accagacaat aagtggcgaa tgtttgaaaa ggaaacagct gggtttgctt
    35281 ttctttttag atgttcgctc tatttttctt tattacattt tttgctcttc acggatacgt
    35341 gattccaatt cgtgttgttc acgctctttt tgtgcttgac gttcctcttc ttccatcttc
    35401 aaacgttcac gttttaattc aggatgtgga tcattgacta catttcctgc atcgatttct
    35461 tctaaagctt gaccgacgct ttttactgaa tcaaaagaat ctagagtagg ctgtgcactt
    35521 gcatccaatt catgcgcgcg tttacttgct aaaatcacta gagaatattt tgaatttaca
    35581 cgatctaata gtgagtcaat tgaaggtttt aacatcataa gactacatct cctttaacat
    35641 tttaatatat ttaccgatta cgcgatctac tcgaaaatgt tcactggcaa taatgttttt
    35701 gattcgttca actgctagcg gcacttcatc atttacaaca gcatagtcgt aaagagccat
    35761 catttcgatt tcttcttttg caactttcat tcgttcttcg attacttcat ctgcatctgt
    35821 tcctcggcct acgatccgtg attttaattc cgctaaatct ggcggagtca aaaagatgaa
    35881 tacaccatcg ggcacttttt ctttgacttg ttttgctcct tggacttcaa tctccaagaa
    35941 aacatctttt ccttcatcca atgtcttgtt gatatatgac aaaggagttc cataataatt
    36001 cccgacatat tctgcgtatt ccagcatctc tccagcttcg atcattgatt caaactcttc
    36061 tttgcttcgg aagaaataat caacgccttc gacctcccct tcacgcattt tacgggtagt
    36121 cattgagatc gaatactgaa aatcattatc ctcactctca aaaattgctt ttcgtactgt
    36181 gccttttcct acaccggatg gaccagacaa cacgattaat aatccacgct ctgacatgac
    36241 gacgtccttt caactagtct ttttgtactt atcgtttatt ttgcactttt tttctgcaac
    36301 tttcaaggtt atctttaatt atagctagaa attggtaaaa aagctaccct gtaccaagag
    36361 gtcgtaaaaa agctgtcctg catcaagtaa taagaacagc caaacataaa cagcttctca
    36421 tgtttttcgt ttggttgggg ttattatcgc agatgcaagc ttttgaacgc cgtgtataag
    36481 aggtcgtgaa gaagccgatt agtttcgagt atgaagaaaa attttgtgaa aatagtttct
    36541 cacatttttg cataaatttg gcttaata
//
LOCUS       DACDLM010000023        35988 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.023, whole genome shotgun sequence.
ACCESSION   DACDLM010000023 DACDLM010000000
VERSION     DACDLM010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35988
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.023"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            17..247
                     /locus_tag="IV356_001189"
     CDS             17..247
                     /locus_tag="IV356_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014891.1"
                     /translation="MGFRTKRSLSSKKNWVYSQTIFYGGIVLISLLSSTLYSLNIIDV
                     STSNSISIIGIIIAAIITQLFLVFGEKKRSKK"
     gene            complement(338..703)
                     /locus_tag="IV356_001190"
     CDS             complement(338..703)
                     /locus_tag="IV356_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014892.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            911..1393
                     /locus_tag="IV356_001191"
     CDS             911..1393
                     /locus_tag="IV356_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014893.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1590..2480
                     /gene="pstS"
                     /locus_tag="IV356_001192"
     CDS             1590..2480
                     /gene="pstS"
                     /locus_tag="IV356_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HAP9014894.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            complement(2767..4041)
                     /locus_tag="IV356_001193"
     CDS             complement(2767..4041)
                     /locus_tag="IV356_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP9014895.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMNSVSGSMSFICVDGTTNQLFTILEDRRLYKLTQYFLRFPRKARLKVKYLV
                     MDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYR
                     RLKRYWKLLLKDSTTWEPLKRHYHRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLR
                     YYFVKRGTEGFQETLKTISSTLPQSFKKKFTIFHCYQSGISNAFKVSHSNGVTEGLNN
                     KIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
     gene            4314..6785
                     /locus_tag="IV356_001194"
     CDS             4314..6785
                     /locus_tag="IV356_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAP9014896.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(6888..8624)
                     /locus_tag="IV356_001195"
     CDS             complement(6888..8624)
                     /locus_tag="IV356_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HAP9014897.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(8621..9325)
                     /locus_tag="IV356_001196"
     CDS             complement(8621..9325)
                     /locus_tag="IV356_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP9014898.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            9456..9959
                     /locus_tag="IV356_001197"
     CDS             9456..9959
                     /locus_tag="IV356_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HAP9014899.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            9919..10257
                     /locus_tag="IV356_001198"
     CDS             9919..10257
                     /locus_tag="IV356_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HAP9014900.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            10278..11696
                     /gene="ffh"
                     /locus_tag="IV356_001199"
     CDS             10278..11696
                     /gene="ffh"
                     /locus_tag="IV356_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HAP9014901.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            11808..12386
                     /locus_tag="IV356_001200"
     CDS             11808..12386
                     /locus_tag="IV356_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HAP9014902.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            12390..12911
                     /locus_tag="IV356_001201"
     CDS             12390..12911
                     /locus_tag="IV356_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP9014903.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(12990..13544)
                     /locus_tag="IV356_001202"
     CDS             complement(12990..13544)
                     /locus_tag="IV356_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAP9014904.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            13797..14072
                     /gene="rpsP"
                     /locus_tag="IV356_001203"
     CDS             13797..14072
                     /gene="rpsP"
                     /locus_tag="IV356_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HAP9014905.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            14084..14335
                     /locus_tag="IV356_001204"
     CDS             14084..14335
                     /locus_tag="IV356_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAP9014906.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            14460..15251
                     /locus_tag="IV356_001205"
     CDS             14460..15251
                     /locus_tag="IV356_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014907.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            15421..15942
                     /gene="rimM"
                     /locus_tag="IV356_001206"
     CDS             15421..15942
                     /gene="rimM"
                     /locus_tag="IV356_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HAP9014908.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            15932..16693
                     /gene="trmD"
                     /locus_tag="IV356_001207"
     CDS             15932..16693
                     /gene="trmD"
                     /locus_tag="IV356_001207"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HAP9014909.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            16829..17176
                     /gene="rplS"
                     /locus_tag="IV356_001208"
     CDS             16829..17176
                     /gene="rplS"
                     /locus_tag="IV356_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HAP9014910.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            17434..17727
                     /locus_tag="IV356_001209"
     CDS             17434..17727
                     /locus_tag="IV356_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HAP9014911.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            18570..20897
                     /locus_tag="IV356_001210"
     CDS             18570..20897
                     /locus_tag="IV356_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP9014912.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSATETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            21023..21352
                     /locus_tag="IV356_001211"
     CDS             21023..21352
                     /locus_tag="IV356_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HAP9014913.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     AEIKTSD"
     gene            21392..22396
                     /locus_tag="IV356_001212"
     CDS             21392..22396
                     /locus_tag="IV356_001212"
                     /inference="COORDINATES: protein motif:HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAP9014914.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKTKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            22393..23822
                     /locus_tag="IV356_001213"
                     /pseudo
     CDS             22393..23822
                     /locus_tag="IV356_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306286.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
     gene            24028..25200
                     /locus_tag="IV356_001214"
     CDS             24028..25200
                     /locus_tag="IV356_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP9014915.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(25362..25817)
                     /locus_tag="IV356_001215"
     CDS             complement(25362..25817)
                     /locus_tag="IV356_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014916.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQQAAAEQASQQAQAAAP
                     EQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSKCYGN"
     gene            26407..26829
                     /locus_tag="IV356_001216"
     CDS             26407..26829
                     /locus_tag="IV356_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP9014917.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            complement(26995..28188)
                     /locus_tag="IV356_001217"
     CDS             complement(26995..28188)
                     /locus_tag="IV356_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP9014918.1"
                     /translation="MTTYQRKLLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            28412..28789
                     /locus_tag="IV356_001218"
     CDS             28412..28789
                     /locus_tag="IV356_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP9014919.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            28777..29115
                     /locus_tag="IV356_001219"
     CDS             28777..29115
                     /locus_tag="IV356_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP9014920.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            29249..29692
                     /locus_tag="IV356_001220"
     CDS             29249..29692
                     /locus_tag="IV356_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HAP9014921.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            29954..30769
                     /locus_tag="IV356_001221"
     CDS             29954..30769
                     /locus_tag="IV356_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP9014922.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            30779..31441
                     /locus_tag="IV356_001222"
     CDS             30779..31441
                     /locus_tag="IV356_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAP9014923.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            31646..33310
                     /gene="alsS"
                     /locus_tag="IV356_001223"
     CDS             31646..33310
                     /gene="alsS"
                     /locus_tag="IV356_001223"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HAP9014924.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            33323..34033
                     /gene="budA"
                     /locus_tag="IV356_001224"
     CDS             33323..34033
                     /gene="budA"
                     /locus_tag="IV356_001224"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HAP9014925.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            34163..34660
                     /locus_tag="IV356_001225"
     CDS             34163..34660
                     /locus_tag="IV356_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HAP9014926.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            34845..35105
                     /locus_tag="IV356_001226"
     CDS             34845..35105
                     /locus_tag="IV356_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014927.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(35467..35706)
                     /locus_tag="IV356_001227"
     CDS             complement(35467..35706)
                     /locus_tag="IV356_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014928.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
BASE COUNT        12092 a         6324 c         7207 g        10365 t
ORIGIN      
        1 gagtagaaat tcaagtatag gttttagaac taaacgaagt ttgtcttcta aaaaaaattg
       61 ggtatactca caaactattt tttatggagg aattgtttta attagtttac tttcttcaac
      121 actttattct ttgaatatta tagatgtttc cacctcaaat tcaatatcta ttattggaat
      181 cattattgct gcaattatta cacaactgtt tttagtgttt ggagagaaga aaagaagtaa
      241 aaaatagaaa aactagtgat agttttggtg atataagaaa aacatatatg tataaaaaga
      301 agaaagtagc ttctctttgt acatatatgg tttgttttta tggatgccga gcttttttat
      361 aagataaggc taccgcccat aacgacccaa ggatttgtgg aactaagtaa atacctgcaa
      421 gaagcaagat cagctgggtc ggttttaaag gatgatagaa gtaacgccat tcagtaaaat
      481 tggcgcaaaa taaataggaa gtgacagtag atataatatt ggcaatgaat aaagatataa
      541 tacgcctgtt cctttgaaaa taatatccag caaaaagaga taaaaatatc aatgtgatga
      601 acccgcttac ggaatgataa cgaaaatcaa gcagtaaggc gaaatgcaca taaggaacaa
      661 aagataaaag caacggaagg tttttccagc aagtttttat catctttcat caccacctaa
      721 caagtgttat tattttgtta gttttattgt aaattgaatc ctgcaataat caattacttt
      781 ttcattattt ctagattaaa tgaataaact ctcatgccat tatctctaaa aaaaaagttt
      841 ttccccctaa tttttttaga tagaaaattg tatagtatga tgagagaaaa agtagtttgg
      901 gggaacgtta atgagaagaa aagcagtaat cgatcggctt tatttatttt tttggttttt
      961 tcctatcgtt ttgctacctt ttacatgggt aaatgctgtt gtacaaggtg cggagatatt
     1021 aggcctgatc caaggaagcg gatttgtggt ttctaggaat tttccagctt tgattgtttt
     1081 ctatttagtg ataagtgtag gtctcttatt accaaaatct ctgatcaatc actacaattg
     1141 gcagctgctt tacttttctt gcttattagt atttacatct atgttttctt tgctgcctcg
     1201 cttgattatc ggccctaatg gtttgagcga gagtggattg aaggatttag cttattcctc
     1261 catgtatttc ttgacgatca aaccatggtt ctatttagta attgcctcat ttattcttgc
     1321 aacatttttt tacttctgga cagaaatcag gataaaaagt gaacgatctg tatctataaa
     1381 aaataactat tgatggtgga tcatcagtaa aaaaacatat gagctgcgta aaatgcatgt
     1441 ttctcatatg ctttttttat tattatgtaa agaatgcgaa aaacgtttac atgattttta
     1501 cataacttaa ctatattttt acagcaacca tacgagggat ttacagtcga ctgataaact
     1561 ttagttgtaa ataagaaagg agcaataaaa tgaaaaaagt attgtttact ctaggtatga
     1621 tgggaattct tttagccgga tgcggctcag gatcaggaaa tacagatggc tctgccacac
     1681 aaaataattc aagtgactca aatgaacaag taaaaatcgt tgcggtaggt tcgacagcat
     1741 tacagccgtt agtcgatgca gcacaagaaa gctttgtaca agaaaatcca aattatcaaa
     1801 tctctgtaca aggaggagga agcggaactg gtttgagcca agtcgaagct ggagcagtta
     1861 ctatcggaaa ctctgatgta tttgcagaag aaagagacgg agttgatgct tcaaaattag
     1921 tggatcataa agtagcagtg gtcgggatgg caccaatcgt caataaagat acagatgtca
     1981 aagatatcac caaacaggaa ttgattgata tctttacagg aaaaatcact aactggaagg
     2041 aagttggcgg gaaagatcaa aaaatcaacg tcgtgaaccg tgcaaacggc agcggtaccc
     2101 gcgcgacatt cgaaaaatgg ggactggatg gtgctacccc tgtgcagtcc caagaacaag
     2161 attcatcagg aacagttcgg cagctggtaa gtcaaacacc aggagcaatc agctatttag
     2221 ctttctcata tctcgatgat tccacacaag cactaagtat cgacggtgta gaaccaaaag
     2281 aagagaatgt agcagataac agctggggaa tctggtcata tgaacatatg tacacgaacg
     2341 gaaaaccttc ccctgaagtc caaaaattct tagactacat gatgacagaa gaaatccaag
     2401 aaggacctgt caaagaattg ggctatttac caatcacaat gatggaagta gaacgtgatc
     2461 acgaaggaaa tatcaaataa ctagcagata aacatgccac ggtagtcgtt actattaagg
     2521 aaaaatcaac tatgtttccc cacatataca tttttccttt aattgtgaaa aatagttcct
     2581 catattttgc cgttttttga gctaataccg agggtcagct gattgaacac cgtttattcg
     2641 aaaaaaagag ctacgacata gaactgtcgt aacttttttt ggctcttcgt caaatcgtgt
     2701 tggtgaagac aaatttgaat aaaacttagt ccgatatgcg gcgcgttctg tgcgccgcat
     2761 atttttttag ttttcaaaga tcagaccttg ttgtaaatag atccgtgccc gaaagttata
     2821 aaagttgcga taaccaaacg caattcgttt aatcagcttg atcttgttat tcagcccctc
     2881 agtgacgccg tttgagtggg acaccttaaa ggcatttgaa atacccgatt ggtagcaatg
     2941 gaagatcgtg aatttctttt taaacgactg aggtaacgta gatgaaattg ttttaagggt
     3001 ttcttgaaag ccttccgtac ctcgtttaac gaaataatag cgtaataatt gacaaaaatg
     3061 atacgcagtt cgcaattctt cgttgtagct taacagctca tcaacgattt ctgtttgact
     3121 aattggtcgt ttaaacagtc gatgataatg ccgtttgagt ggctcccatg tcgtggaatc
     3181 tttgagtaag agtttccaat atcgcttgag ccgacggtac ttcttctgat tttcagagtg
     3241 tgaggttcga aaacgattca tgatctggac acgtaattga ttgaagctgc gattgatgtg
     3301 ttggacaata tgaaagcggt cagttacgat ctccgcattt ggaaagactg ttttaagcaa
     3361 ctgacaatag ctggcattca tgtccatcac taggtacttg acctttaaac gggcctttct
     3421 aggaaagcgc aggaagtatt gagttagttt gtaaagtctg cgatcttcaa ggatcgtaaa
     3481 tagctgattg gttgtcccat caacacaaat aaaactcatg gaaccagaaa cagaattcat
     3541 tgatttgaac tcatccatac acaacaccgt cggaaggaag ttcatacgtg gctggtaatg
     3601 cttcgttgct tcacgcaaga tccgtgtcac cgtcccatcc gagacgaagt acttcttagc
     3661 gattagttta cgtgattgat tttcgtacag ttccatgaga atcgcctgct tcagttcctt
     3721 tgttagttga tgatgttcat caactaagtc cgttttcgca gaaaaggtcc ttccacaatc
     3781 atggcagaga aaacgggtac gttttaattc taaaatagtt aacttttctt tgactttcaa
     3841 catctgagtg cgtgtcgtat aggaaccgtt gcggataata cgaaccgatc gacagtgttc
     3901 acaataggaa gaagagtcat ccaattttcc tttaataaac tgcgcttgaa cgcctttata
     3961 ttctttttca atcagccatt cttcatcaaa aaataaatgt ttatctgtta atccgagtaa
     4021 ttttctagta tgattatcca ttgagagact cctttggtag gatgacgttt tggtcgacta
     4081 aattttacca aaagtgagtc tctttttgag ttgaaacgaa gaaaaagtgt tagtagaaaa
     4141 tcgccttcga ttttccacca acacaaaata ttatagaacc cttttttttt gctatatgac
     4201 aggaatgaaa ggtgtttgca agcttaatgt gaggaacact ttccatatct gttctatact
     4261 ggataggaga agtttggaaa tatccagaaa acgaaatcaa tcgaggtagc cacatgaaga
     4321 ataaatggat aaatcgaagt aaaaaaaaga aagtaacaca aagatcatca gataaagtca
     4381 tccgtctttt tccatcgtat aaagaaggat taacggcaga tcaagtcaag gaacgaatag
     4441 aaaaaggtgc agcaaataat tcagtcgatc ccacattcaa aacaaatcag caaatcgtat
     4501 tggaaaacat atttacgtat ttcaatttga tctttcttat cttagccatt ttgctttgtt
     4561 tagtagaatc ctataagaac ttgacttttt taccagttat catagccaat acaggaatcg
     4621 ccatttttca ggaaattcga tccaaaaaga tcttggacga actaaatgtt ttaaatacag
     4681 caaaagtcaa tgtcatacga gacgggatag aacaaacaat agatatagaa gaccttgtaa
     4741 tagatgacat tgttatttta gagactggat atcaaattcc agcagatgca gaggtcgtgg
     4801 aagggaaact gcaagttaat gaggctttat tgacaggcga agcagatgaa ataaccaaag
     4861 aaataggtga tccattaatg tccggcagtt tcattgtttc cggaaaagct tacgcccgat
     4921 tagacaaagt tggagcagat tcgtatattt cccagctgac agtcaaagcc aagacaatgg
     4981 gagaaggaga acagtcggag atgattgctt ctcttaatca attgatcaaa tggattggga
     5041 tcatcattat tcctatcggt atcctgcttt tttctcaaag ttactttttt aatggaaaca
     5101 cgatcaaaga aagtgtcgtt gcaatggaag cagcattgat cggtatgata cctgaaggac
     5161 tgtacttgct gacgacgatt gcattagcat taagtgcgac taaactagca aagcaaagag
     5221 ttcttttaca caatatgaaa agcattgaga cattggcaag ggtaaatgtc ctttgtgtag
     5281 ataaaacagg aacgatcaca gaaaataaaa tgtctgttca aaaaatgatc gtctctaaaa
     5341 aacaagaaat aatcagtcag tcagatcaat tggaagcatg cattgctgac tatgcaaaag
     5401 cgatggcagg agacaatgca acaatggaag ctgttaaagc atattttaca aaaaccactg
     5461 atcaatccta tcaccatgtt attccttttt cttctgtcca aaaattcagc agtgtagcgt
     5521 tggcagacaa ggtgtatgtt ttaggagcgc ccgaaatggt tttgcgcgat caattgccgg
     5581 aatatgcgga agagtttgtt tctttcgctg aaaaaggcta tcgcgtgttg gtctttggtg
     5641 tgtacgatgg gattcttgaa gaaccagtat tgacagaagc agtcacacca ttaggctata
     5701 ttctgattgc taatcctatc agaaaagaag caagagccac atttgattac ttcaaaaaac
     5761 agcaagtagc catcaaagtg atttctggag ataatccgct caccgtatcc aatgtagctg
     5821 tccaagcagg gatttcacat gctgatcagt acgttgatgc atctaaatta tcagaagaag
     5881 aatatgaagc agctgtcgaa aaatatacag tttttggacg cgtcaagcca gaacaaaaga
     5941 aaatcttcgt tcaattgata aagcgtaaca atacagtagc tatgacaggt gatggcgtga
     6001 atgatattct agccatgaaa gaagcagact gcagtatagc gatggcttcc ggaaatgaag
     6061 ccgccatgca ggcctcacaa gtggtcttac ttgattctga cttttcacgc atgccagaag
     6121 ttgttgcaga aggacggcgc gttgtgaaca atattgagcg atcagccagc ttgtttttag
     6181 tgaagaatat tttctccttt ttgctctcac tgttttcagt gatctttgct ctgacctatc
     6241 ctttagaacc atcacaaatc acattgatta gtttgtttac tatcggactt ccatctttct
     6301 tgcttgctct agaagaaaac aaaaagcgaa tcagagggaa attcatcatg aatgtgatgg
     6361 aaaaagctgt gccaggtgga ctaacagata tgatcgtagt cggtgcgttg gtgatctgcg
     6421 gggtgacttt gaatctaaat aaaacagatg tttctacagc atctaccatg cttttgattg
     6481 cagtagggtt cctcgttctc tataaaatct gttcaccgct gaataaattc agaagtcaga
     6541 tcattctttt ctgtgctagc ggtaactttt tttcggtcat ctttttgcat aagctgtttt
     6601 caatcaccgg tatctcagct gtatcacttt tgctgttgag cattctattt ttctcggcag
     6661 attcgatttt taggcatttg accacattgg tagaatattt gtttgaacgt aaaaatgaaa
     6721 aagagcaaaa gccgtttagt cgcgtagcta aaaaatttct atcgatattt aaacgagaaa
     6781 attgacgaaa agtatctcaa aaaagagtaa aaaagaacaa ccactcgtgt atctttcgaa
     6841 gcaggatgag tcatccaact ttaaaacgca cgagcagttg ctctttttta cattttcgga
     6901 atggtaacgg tgaaagtcga acctgttcca agatgactgt ctacagtaat cgtaccatta
     6961 aggagttgca cgtagtcttt tacaatcgct aaccctaatc cggtcccgcc tgaatgtcgg
     7021 cttcgcgcct tgtctacgcg gtaaaaacgc tcaaagatcc gttcctgatc ctcaatgtcg
     7081 atacctatac caaagtcttg gacagaaaac gatagatcat ctgttgcctg atagcggata
     7141 ataatctcgc tgtcgctttt tgaatattgg acagcatttt caatcagatt tttgataatt
     7201 ggataaagga tatctgtttt agtagtaaat ggttcgttct ttccaatcaa tcgaatcgtc
     7261 aaccgtttct tttcgatgat tggctgataa ttttgaacga tttgctggaa ataaggttct
     7321 gtataaattg tctggatctc gtaagaattc tcgccatctt ttgacagctg gatgatttcc
     7381 cgaatcagtt tatctaaccg gatcgcatct ttttgcatga tctcaagaaa agaagtcaga
     7441 gtttgcgggt catcttttgc accatccagt aaagtctcgg taaaaccaat cagtgaagtc
     7501 acaggagttt ttaattcgtg agagacgttg ccaacgaaat ccttttgtag cttttctaaa
     7561 cgtcgcactt tcgttaagtc atacgccacc cctagaatct gtccggtacc ttctgaatta
     7621 gtaaagtagc gcaaactcaa gtctaatgtc tgccgacctt ctgtaagggt gatctcctga
     7681 tggatcagcg gatgctcagg agtcacttga tgaatcagct gaatgagttt tggctcttga
     7741 atgacttctg tgtaccgctg ttcaggttga tagcttacca cgtttaaatg tagctgcatc
     7801 tttggattaa gcagtagtaa acgagaatca gcatcatcaa tcaggaatac gccaatcatc
     7861 agttcgttca gtaacgtata taattgctct tctgtggtag tacacgcccg atacatctta
     7921 ctcatttgtt cgctcaacgc attaatcgtc tgatacaatt cttcccattg atcgggtgtt
     7981 tgcatgatta cttccgcctg attaggattt tgcaccattt tttttagtac gggcagcacg
     8041 gttttcaatg gctggttttt ttgatagatc agataataga tcattcctgc aagaacaagg
     8101 aagaaagaca gaaagaagaa aaagacccaa cggcgaaaac tctcagttct cggtaaaaaa
     8161 acgcttgtcg gttctgcgat acgtaaaatg gcttctaact ggccactttt tttgactggt
     8221 aatgcgacat ataaaagatc ctcattcaaa gtagtacttt tgcgcaaagc gctacctagg
     8281 ttcccaccat tcaatacggc tttgatttcg ggacgggagt ttcgctgttc attcaatgtt
     8341 tcattgtttg tgtcaaataa gatctttcca gtagcatcca ttaaagtaat ccgttcgttc
     8401 gactgatgga cgaattcttc caaagcagtt ttgttttgcg ctgcttggag gttttcgaca
     8461 tctaattgcc ggatcagcag ttgtgctttt tttgtcaggt agctttcttg ctgttccacg
     8521 atctgctgtt gaaaataatg ggaaatcaat tgccagccac caaaaaacaa actaactaaa
     8581 agaataagaa agaagagacg ttcataaatt tttttccatt tcatcgtttg ggttcctgaa
     8641 acttatagcc aaatcctcta atagtcacca agtactttgg gtgttttgga tctcgctcga
     8701 ttttttctcg caaatgacta acgtgtacat ctacgattcg gctttgtcct gcgaagtcaa
     8761 aattccaaat gcggtctagc aatgtgtctc ggtcgatcac acggtctttt cgtttcatga
     8821 aataaacaag taattcaaat tctttcggtg ttagttcaat cagatggtcg tctacggtca
     8881 cttgataatt ggtcaaatca gcagtgattt gtccaatcga tagatattca ggctcagctt
     8941 catcttttga ttgcttacga ggttcaattc gtctgaatat tgctttcata cgggctaata
     9001 cttcgcgagg actaaatggt ttggtcaaat agtcgtcagc acctatttct aggccaatga
     9061 tccgatccac ttggtcatct ttagccgtca gcatcaaaat cggtgtttca tttttttctt
     9121 gacgcagccg ctgagtgatc tccatgccat ccatcgttgg aagcatcaca tctaaaatga
     9181 tgaaatcaaa tgattgttct aatgctaatt ctaatccttc gcctccatct gtggcactgg
     9241 ttaccttgta gccttctttt tccaaattga acgtcaagag cgttacaata gaaggttcat
     9301 catcaacaac tagtattttt ttcattcaaa tctcctttaa ataggtttca ttctgtttat
     9361 attttagcat agaatcagta caaagggcta ttttacaaaa gaaataaatg gtataatagg
     9421 aaggcacttt gctgaataga aaggaagagc agtcaatgat tggaatcagt gcatgtttag
     9481 gcggtctggc ctgtcgctat gatggacaga aaaaagaagt accagaattg atggaactag
     9541 ttgaaactgg agaagctgtc atggtctgtc cagaagtgat cggcggatta ccaattccta
     9601 gagatcccgc tgaaatcatt ggtggaaatg gattcgatgt gtggaaagat caagcaaaag
     9661 tatggacgac aagcggcgaa gatgtaacgg aagcgtacaa aaatggcgcg atcaaagcct
     9721 atcaaaaatt gcaggaaaaa cacattgatc tagtcatcat gaaggaaaaa agcccttcat
     9781 gcggaaccca ttcgatttat gacggaagtt tttccggaat aaaaaaaaat ggtgccggag
     9841 tggctactgc ttattttatt cagcaaaaaa tgactgtgct ctctgatgaa gaatggctga
     9901 aaactagagg tgagcagaat ggaaatcgaa aagaccaatc gaatgaacgc gctctttgaa
     9961 ttttattcga ccttattgac agaaaaacaa atgaactaca tggaattata ttatgcagat
    10021 gatttttcat taggtgagat cgcggaagaa tacgaagtaa gccgacaagc agtatatgac
    10081 aatatcaagc ggacaagcaa gatcttggag gattatgaaa aaaaactcca tcttttttct
    10141 aattatattg ttcgagaaca ggtattggaa aatatgactg catatattac agataagtac
    10201 ccggaagata aaaaactact tgaatatgta cagcaaattc aagcaatcga agaataaata
    10261 aaaggaatga agaaaatatg gcatttgaaa gcttaactga acgtctccag caggcgatgg
    10321 gaaaaataag aaaaaaagga aaagtatcag aagctgacgt aaaagaaatg atgcgggaaa
    10381 tccgccttgc cttactagaa gccgatgtta acttgcaagt agtcaaagat tttactaagc
    10441 gcgtacgcga acgtgcggta ggggcagaag tgctggaaag tttatcacct gcacaacaaa
    10501 tcgtaaaaat cgttgatgaa gaattgacga tcacacttgg ttctgaaaca gcagagttaa
    10561 ataaatcacc aaaaatacca actgttatca tgatggctgg tcttcaaggg gcaggtaaaa
    10621 cgacctttac tggtaaatta gccaattatt taaagaaaaa tgaaaatgct cgtccgctcc
    10681 taatcgcagg ggacgtatat cgaccagctg cgatcgacca attgaaagta ttaggtcaac
    10741 agctagacgt tcctgtattt gatatgggaa ctgaagtcag cccggtagag atcgtccgtc
    10801 aagggatgga gttagcaaaa gaaaagaaaa acgactatgt attgatcgat acggcaggac
    10861 gtctgcatat cgatgaaaca ttgatggatg agttgaaaca aatcaaagaa ttgacgcaac
    10921 caaatgagat tttgcttgtt gtcgatgcca tgactggtca agatgccgtc aacgtagctg
    10981 atagcttcaa ccagcaatta ggtattacag gggtcgtcat cactaaactt gatggggata
    11041 ctcgaggcgg ggcagcacta tcgatccgct cagtgacagg cgcaccaatc aaattcatcg
    11101 gttctggtga aaaattgact gacttagaag tattccaccc agatcgtatg gctagccgta
    11161 tccttggtat gggggatatg ctgacattga ttgaaaaagc gcagcaagac tacgacgaga
    11221 aaaaagcgga agaacttgca cagaaaatgc gggaaaattc attcgatttc aatgacttta
    11281 ttgaacagct tgatcaagtg atgggtatgg gcccactgga agatctaatc aaaatgatcc
    11341 caggaatgaa tcaagtccct ggaatcgaaa acgtcaaggt agatccaaaa gatgttgaac
    11401 gcaaaaaagc gatggtttat tctatgacgc cagcagaaag agcaaatcct gatctgttga
    11461 acccaagccg tcgtcgccga attgctgccg gttctggaaa cagtgttgtt gaagtgaatc
    11521 gaatgatcaa acaattcaag gaatcaagaa aaatgatgca gcaaatgtcc aaaggggata
    11581 tgaacatccc aggtatggac caaatgtttg gttcaggcgt caaaggaaaa ctaggcaaaa
    11641 tggcgatgaa tcgaatgatc aagaaaaata agaagaaaaa gaaaaaacgg aaataagatg
    11701 aaaaaaacag cttcggtaca gactgaaaat gtctactgcc ggagcttttc tatcagcaat
    11761 ttttattctt tactaataca attactctaa acgaagaggt ggcacagatg agatgtccgt
    11821 ggagtgaaca aacagaaagt atgcggcaat atcatgatac tgtctggggt gttcctgaat
    11881 atgatgacca aaagctgttc cgaaaattga tgcttgatat taatcaagcc ggattgagct
    11941 ggcagacgat tttaaataaa agtgaagcat tcgatgaagc atatgatcga ttcgatatca
    12001 aaaaagtcgc aaattatgga gaaacaaaaa tcagtgaact aatggaaaac aaaggaatta
    12061 ttcgtaaccg aagaaaaatc gaagcagccg tccaaaacgc caaagcagtc ttgaaaattc
    12121 aagaagaaat cggcagtttt tcagagtatc tttggtcgtt ttctaatgga aaaatcgttg
    12181 attcttctta tcattcacaa gaagaagtcc caacaacaag tcctctttca gatgaattag
    12241 caaaagatct aaagaaaaga ggatttaaat ttatcggaag cacaacaatc tatgcttttt
    12301 tagaagctgt cgggatcatc aatgatcacc ttgacagttg tttccgcaaa gaagaggtcg
    12361 tacgtatcgg cagaaagggc gaataaagca tgcgaaaaat catattttat ggtgctataa
    12421 gtttagatgg ctatttggca acgaaaacgg atgatcttca atggcttttt gacactccaa
    12481 caggtaagca aactacttat gaagcttttt atgaaacaat cgatacgacc atcatgggca
    12541 gaaaaactta tcaggaagca aaaaaatatt tggagaccga agcaatttat ccagagaaaa
    12601 agaatttcgt tttttccacc cacgcacaat tacaattgcc agatgctgag gtcgtaaacg
    12661 aagatcctgt tgcttttcta aaaaatctac aaatgacaga aggaaaagat atctgggttg
    12721 tgggtggcgg tcgattgatc aaaccgctat tggaacatca aatgattgat gaatggtata
    12781 tccagattac ccctgtatta ttaggggacg ggattccttt attccaaaaa ggaacatatg
    12841 aagcgcgttt tgaaatgcta gacacgacac gattcggtga atttatcgaa ttgcattatg
    12901 tacgaaagta gaagtaaata aaataaaaaa ggcaactata tgcagaaatg tcctgtacat
    12961 agttgccttt tttattaccg ttatgctttt tactctgtta atttgttaga aaaatctaga
    13021 tacgcatcta aaatcgtttg gaagaaactt aatgttcctt caacgatatt accattttca
    13081 tcaattagat tcgcaacgtt tccgatatat gcttccggtt gctgcaaggt tggcacattc
    13141 aaaaagacaa gtgattggcg tagatggtgg tttgcgccaa agccgccgat cccacctggt
    13201 gatgcagtaa cgactaaacc tggtttatga tcccaaacac tgtgtccata aggtcttgag
    13261 cctacatcta aagcattttt caatactgct ggcacagaac ggttgtattc aggagtaacg
    13321 aaaacgacac cgtctagtcc cctcacttcc tcacgaaaac gagtccattc agcaggagcc
    13381 tgttctggag tttcgagatc ctcattgtaa aatggcagat catcgatttt tacaaataca
    13441 ctttcgtacc cttcaggaag caatttcgca aaagcttctg ctactttttt gttgtaagaa
    13501 tcttttctta aactaccaat aaaaaatcca attttttttg tcatacgatt tttcctcctt
    13561 caaactatct ataataatct tacaaaagat aagtaactgg agcaaataaa aacacttact
    13621 gacaaaagct acatagaaga tagattactt atttttaaca aaaaagaagt ctaaaatctt
    13681 ctattttcta aaaaaaatcg aatttaatca agctgtaaag aaaaaaagct ttacagggta
    13741 aaaaaaaact gttacactac atcttgtgaa taaaacaatg gaggtggaaa taaataatgg
    13801 cagttaaaat ccgtttaaaa cgtatgggtt ctaaaaagag tccgttttac cgtatcgtcg
    13861 tagctgattc acgttctcct cgtgatggac gtttcatcga aactgtaggt acttacaatc
    13921 ctttgaaaga ccctgcagaa gtagttttaa aagaagactt agttcttgac tggttatcaa
    13981 aaggtgcaca accttctgac actgtacgta acatcctttc aaaagaaggc gttatgcaaa
    14041 aacaccacga agctaaattc tcaaagaaat aaggtgaccg gatatgaaag atttaagcga
    14101 cttagtctta acaatcgttc gtccgctagt cacttatcct gatcaagtca agttagacgt
    14161 cgtagagtcg aaagactttt acgagtacaa tctaacagtg gctcctgaag atattggccg
    14221 tatcattgga aaacaagggc gtgttgctaa agcaatccgc acaatcgttt acggtgttcg
    14281 gatcaatgca ccgaaaaaag tgcgtttgaa tatcatcgat gataaggaaa agtaaataaa
    14341 cgtgctgtac tcgaattttc gagtgcagct tttttgtttt ttttattaat tgaagaaatg
    14401 attatttggc aaaacaagca agaaagcgta tccttatagg aggagggagt gaacagccaa
    14461 tgagaaagaa aatgttattt attccatttg ctctattgtt aagcgcttgt agttcggtta
    14521 ctcaagaatc agacaataca catctatcaa gcagtatatc tgaaactgtt accagtccag
    14581 aaaaaagtag taccaaaacg gcttccacca ctgaacaaac aatggctacc tcaaataatg
    14641 agaaaaagac tgctttagac cagttgaaag aacaacagcc aaatgttccc atgcctctag
    14701 atgtaccagt ctcttcaggc tatctcaata tcgcagcgac acatacaaag caaggttatt
    14761 ctattttata ttacagaaca gatcgtcccc tcgggttgaa tgctgacgaa ttgaatcaag
    14821 aaacgcctat tgcaacctat ctatatcaat atgggtttgc ttctagtcaa gaaacaatcc
    14881 aagttttgca gccatttgag atcgacacaa atggtcagca agtggactta ggttctcgaa
    14941 tcacagggta tcagcaaggt gcagcaggtt caagttttct tgaatggcaa gaaggaaact
    15001 ggcgtattcg aatccgtggg aataatatag aaggccaaga tcccttacta ttagctaaag
    15061 aaatcgtagc ttatttggaa gaaaacagtc taccagcacc tgaacaattt ggtaaaatta
    15121 ctgttgatat gggtgatacg acgaatcgag ccgtagaagt aagctggcaa gaaccgaaaa
    15181 atgcctatac gatcactcat caagatccta tgtctgcgtt gaagatggca gtttctatga
    15241 agaggttgtg aaatcagcgc gctgatctga gcccatcatt taactccaag tcacaggaag
    15301 taatcaaaaa tagcacgccg catttttgca taattttggc ttaatacctt aaaagaaaac
    15361 tagaattgcc tcttcacaca tgctaaaata aaacagacaa aaaagaaatg gggatataag
    15421 ttgactgaat acttgaatgt aggaaaaatc gtaaacacac aaggtatcaa aggcgaagtc
    15481 cgtgttatct caacaacgga tttcccagaa gaacgttaca aaaaaggaac ggtgctaaca
    15541 ctattccaag acggaaaagc acctgtggaa ttaacagtca aaagtcatcg caaacataaa
    15601 aattttgact tattgagttt tgaaggacat ccttctatca atgatgtgga aaaatatcgg
    15661 gatggcatat taaaagtgtc aaaagacaac tctgtagatc tagctgaaaa tgaattctat
    15721 taccatgaga tcatcggtct gcatgtatta gaagatggaa ctgagttagg taaagtaaaa
    15781 gaaatcttgt caccaggtgc caatgatgtt tgggtcgttc aacgtccgaa aaaagctgat
    15841 atattgcttc catatatcgc ttctgtcgtc aaagaagtcg atttagaagc tggagtggtc
    15901 cgtgtagaaa ttccagaagg actgattgac gatgaagatt gatgtattga ctttatttcc
    15961 aagaatgttt gaaggtccta tgggggaatc catcatcggt aaggctgtag ataaaggatt
    16021 attagatatc aatatctcta acttccgcga ttattcagat aacaaacatc agacagtaga
    16081 tgattatcca tacggcggtg gagcaggtat gctgctcaaa gtccagccca tctatgataa
    16141 catccaagcc attgaaaaag ctgcaccgga tgtcaaaaaa agagtaattc ttcttgaccc
    16201 agctggtaaa cgattcgatc agaaaatggc agaagaattt tcacaagaag aacacttagt
    16261 attcatttgt ggtcattatg agggatatga tgaacgtatc cgcacattag tgacagatga
    16321 agtttcctta ggagattatg tccttactgg gggagaatta ggtgcgatgg tcatgatcga
    16381 tgcaacagtt cggcttttgc cagatgtgtt agggaatcag acttcagctc aaacggattc
    16441 ttattcaacc ggtttattgg aacatcccca atatactcgc ccggcagaat ataaagggat
    16501 gaaagtacca gaagtattga caaatggaaa tcataaattg attgaagaat ggcaattaaa
    16561 agaatcacta agaaggacct atcaacgtcg gcctgatctt ttggaaacac ttgaatggac
    16621 acctcaaatg acgaaatttt tagaagaaat caagaaagaa gaacaagaaa aaacagcaga
    16681 tgaagccaag tgactttttc taaaatcttc tttacagtag gttgataata tgttagtatt
    16741 ttatggtgag tgcaaaagca cttaactatt acgatattcc gctgtgagaa aagctcataa
    16801 gaatatttgg aataaggaga agaaaaccat gaatccatta atcgaagaat taacaaaaga
    16861 acaattacgt tctgacatcc cagcgttccg ccctggtgac actgtgcgtg ttcacgcaaa
    16921 agttgttgaa ggtactcgtg aacgtatcca gttatttgaa ggtgttgtta tcaaacgccg
    16981 cggtgctgga atcagcgaaa cttatacagt acgtaaagtt tctaacggag tgggcgttga
    17041 acgtacattc ccattgcata caccacgtgt tgcaaaaatc gaagtagttc gctacggtaa
    17101 agtacgtcgt gcaaaattgt actacctacg tgcattacac ggaaaagctg ctcgtatcaa
    17161 agaaatccgt cgttaatcat tgttatcaga ctgagaaaga acccttggta ttcaagggtt
    17221 cttttttctt agcatgtaat ttgaacaccc tgatccagtt ttttctttaa ttattggtag
    17281 gggagaataa tggattagaa taaatctacc tataagtagt agtaaaaaaa agagcactat
    17341 gataatatct ttcttaagag taaccgcttt aataaaaaat ccagaatatt ctaacataaa
    17401 tggagtattc ttagaatcaa aaggagaaag aagatggttt atacttatac ggagcaagaa
    17461 aagatgaaag ttttagacac attcatgaat gatggaaaag taaaacaagt accaagttca
    17521 acaaaaaaga aatacatcct attgaaagaa gtcttgaaac gctttgacca tggagtgact
    17581 tatacagaaa cagaggttaa ttcgatactg ctgaacgtat tttctagtgg cgattatgtc
    17641 gaacaaagac gttatctaat cacatttggc tttttcaaaa gaagttcaga cggtcgggca
    17701 tatcagatga tgggaattga aaattagaag ttttaattta tactcattga aaaaagttca
    17761 agtatgcgat attggttcta caccgcatac ttgaactttt tttgtcatct gtatctataa
    17821 tacaaagcca agaacgttat tcaaaatatg gatagctatg ataaaagcta atgagcgatt
    17881 cgcagttaaa taagcaatcg tcagtaaaat cgttccagga gcgtacatga aaaaatcaat
    17941 tggatgcgtt acatgaataa agataattct cttttatttg tacgaataaa taccaaaacg
    18001 tacctcctaa aattagattt tggacagatg ccctttaaaa agataacaag atttcgttct
    18061 tgaaacaata tatatgcttt tattccaatg aggttgtgaa aacagtattt tgtcctgagc
    18121 gttagaaaat tgaaaatggg gaatagcaac tcgtacttta ccatttttta agtgaataca
    18181 agatcagcta attgaacacc gtttattcgt gatgagggac acaacactgc agtcgacaca
    18241 tttctctttt atgttcaaag ataacaaata tttaaaacaa agaaaaatag tagataatcc
    18301 cgtcctaact cttttattct tccctcatag cttccaaatt taagcaatac ttcaattaat
    18361 caagttttat cttttttttt caataatcgt aaaaaaagag tattttttat ttaaaaataa
    18421 aatctttgta ttaaaggaca agactaaaat aaccttagaa taaaaagaga aaaaaagccc
    18481 caaactttct atacatcaat aaaataataa aaattaaatt tagaataacg tgtaaaggat
    18541 tatttgatga ttttttattg agaggaggga tgaaaatgat taagaaaact caaaataaaa
    18601 tccaacgtat atgtcaaaaa cattttgttt ctagactcaa agctgtatct aaaagaaaat
    18661 acttacatcc cattatgatt tcgatcatct tgatttttac tttcttaggg agcttatcaa
    18721 gtatttatgt aaacgtttat acagaaacgt caaattttgc taaccaaacg acagaggaga
    18781 caaatagtcc accctattct gaaatacagt ccatagaaag caccaatcag tctagcaaca
    18841 acgagacaac ctcaaccaca tcctcgactc aactgattga tccgacagaa aaagaaatca
    18901 cagcagcaaa agcagcaggg gagaaagctt attcagaaac aggtagaagc cagacattta
    18961 gtactgttgc ggccactgcg aatttcaacg gacataccat accagatgga tatacagtga
    19021 tatatgccaa agatggagtc attgttgcgg ttaacggatc gatgagtgcg gataaaactg
    19081 cgttacaagg cgtaaccaaa gcaatcgctt ttattgataa ccgtccagat atccataatc
    19141 tgtttattgg ctccacagta aatggtacta ctatcacatt cccaaaaagt atctatatgg
    19201 gggtggctac cgctggaaat acgatcgatt cagttacacc caatgcggat aaaagttatt
    19261 cttttacacc ctcaacatgg ggagggcttc ctgccggagg aggtatgagt actttttcaa
    19321 tcggtataca gttagcaaat gatattccat tcacggggta ctcgatcaaa aatgggcaga
    19381 tcgttgatgg taagggaaat gtttcaaatt ttccaaccta tcaagcagca acggttcagg
    19441 tcaatgcgaa tcggacagga actttttctt atacagtcaa tggtggagca gcaaaaatcg
    19501 gaacgtacgg gactacatta tctggaatcc atgtgggtga caaagtggtt atcactccaa
    19561 cagcagtaac gggctattct tttgcacaaa caaacggttc tttcacagcc ctagaaagta
    19621 acgtcgatac ggtgacctat acaggcaaac aaacaccaat cactattaag tatcaagact
    19681 attttggaca gatgattgct ccttctaaaa taatgaatct tacttacgga agtgctgcac
    19741 aagacctgac gactaatacg cctactatca acggatatac ctttacagct gtttcagcga
    19801 cagaaacaaa gaaccaatca gcaatgagtg ttttagctag tttagataca aatggaaatg
    19861 taatcgtaaa ggacgcaaat ggaaaacaga tttctgaagt catcctatat tataagacaa
    19921 atgcaacagt atcaatcaat gcaaatggca gtaagtacta tgatggtctt tctgttgtac
    19981 cgatcgttaa atatgccttt aatgataaaa cagaatcaac atccctttta aacaatgatc
    20041 tcagtattga tcaaatcaca tggaatccaa ctgatttcaa agcgatgaat gaaaagggag
    20101 ttgaagtaac tgcgcctact gaaattggaa cctatacgtc ttggcaattg acaaaaagcg
    20161 gactagctaa actagctgcc agaacaaact atttatttac tatcgtgcag acatctgatg
    20221 tctatacgat taagcaaatc agcggtgcgg tagagctcag tggcagtaag acatatgatg
    20281 gaaaagcagg tgtcccgtca atccatgtca agctagcaga gggtgtcact agttcgctta
    20341 ctccagtaca agtggcactt agcagtatgg attacacagc agatgcacaa tcagcaaaaa
    20401 atatggttaa tgctggcagc tatacaatta aactaacgaa tagcggaata gacaaagtca
    20461 aagcagcaaa tcccaagttg tcatttactg atatagccaa cacatcagga acttatacca
    20521 tctataaagc taacgcagtg attactgtcg atgacgctgc ctttaattat gatgcccaaa
    20581 gtcactcgat ttcggttgga aatctccacg ttaccggtgt tgtcttaggc gaatcattgg
    20641 attataccct aacagttaac agccggacag atattggatc acaaatagta acgattagtt
    20701 taggcgaagg aagtgtaaac aataattata cgattatcgc aacagatacc gctaagttga
    20761 cgatcaatcc gactctcttg cttccttcga caggtgggat aggtctactg ccctttgtct
    20821 ttttaggact gatctttatt ttttctggct tcttttattt tatccatcgt aagaaaaaag
    20881 caggtgaaca gcgatgaaaa aaacaaaaaa tgtacgtgtg gatatatttg ctgttctctt
    20941 ttttatccta ctggtctttt ttataggttc tccgactgtg tcagctagag aatcacctat
    21001 tacatttact ttgcataatc gaatgttcga aagcgataag atgccaagta tcagtcaaaa
    21061 cgacggaata aatatcccgg ataactttca aggagtaaaa gggttgaacg gcgttacttt
    21121 cgctatatat gatgtctcgg atgaatttta caagctgcgg tcagaaggaa gtagtgtgga
    21181 agacgcacaa agaaaactag cacaaaaaag tgatagtgaa aaaatactgg cagaaaatgt
    21241 gacaaaaaca gtagacgagg aagagggcat tgcttctttt agtgcatcgg acaaagatga
    21301 gcaaggtcgt gacgctgttt accgatttgc ggaaataaag acttcagatt aagtaaaaga
    21361 aaaatcagca ccatttgtcg ttgtgcttcc tgtgacagat tcatctaatc ataaattgac
    21421 gaccatccac ttgtatccaa agagcgaaca aaaaatacct gctgcactca cattaacaaa
    21481 aacagtagag aataagcaga cagattttgc agatggggat aaagttcctt atctcatcac
    21541 cgtaacaatt cctgagaaca tcaacgagat aggaacctat acgatcaaag atacagctga
    21601 tcctcagtta tggctagaac cagaaacgat cgattttttg attggtggag acaagattca
    21661 tacatttcac acacaaaaaa caaaacatgg ttttgtctta tcagattctg gaaaagatct
    21721 tagttcgttt gctgggaaaa aattaacgat ccgttaccaa atgacattga aagaaaacag
    21781 tgaaaaaacg acatttgata acgatgtacg tttgacgact gacaatcaaa cagtagaaac
    21841 acatcttgcc atccaaacag gaggcaaaca atttgtcaaa gtggatcggc aaacgaaaca
    21901 aaaactagca gatgctcaat ttctagtcaa aaaaaatgac caatacttag cgcaagaaaa
    21961 cgggataaat cattgggtag ccaaagatga ttcaagagca acgattttta cttccagtaa
    22021 agatggaaca ttttctgtcc atggattgtc ttttggaagt tacgaactag tggagattaa
    22081 accgcctaaa ggatatatat tgagtcaatc aaccattctc tttgaagttg aaaaaggcag
    22141 ttatgatccg cttcatccta taccattgga aatcatcaac gaaccaaaag caaatccgac
    22201 gaataatgga aaaacgccag ttcagatgca gacaaatggt ccatcaaatg aaaaaaatgg
    22261 aggaagcttt ccaaaaacaa gcgaagagat gcttggaggt ttctcaattt tagggttgtt
    22321 gctagtcctt tcaacaggga cagcttggtt ttataaaaaa caacaaaaag gaaacaatag
    22381 gagggaaata aaatgaaaaa catcaaaaca aaaatatgga cgtttttagg aactgctatc
    22441 atgctgcttc ctttcgttct cggcctagga actgcagagg tttctaggcc gtatcaccta
    22501 caccagaaaa tgttacggtt aatttgcata aattgaaatt cacttcagca ccagaaaatc
    22561 aaataaacaa cggaacggaa ttgacatttc cgaatagcga accgttgaac ggcgttgaat
    22621 tcaacgtata tgacatcact gctacgtact atccaagtaa agacacagca gttccagcag
    22681 acgctacacc cttcgcaagt gtaacgactt ctggtgaagg attagctaac ctgactcttc
    22741 caggtaaatc tgatgggaaa gatgctgtat acgtctttgt agaaacacca aagcccggtg
    22801 tcgaaacgtc gccaaatatc gtgttaagct taccctttta taacccgaat tcatcagacc
    22861 ctgacaaacc tttagacacg attcacctat atgctaaaaa tgtcatcaaa gaaagcaata
    22921 tcaaaatcca gaaagctggg aacttttcag gggtagataa gttagcaggg gcgcaattcc
    22981 agatcaaaaa ttcagagaat caattcgtga ccggttttga tgaaaacact ggtgtcgctc
    23041 tctatgatcc tgctgagtca gcgttgacat tcacaactga tactgaagga tccatcagtg
    23101 tcaatggatt aatagacggc aattatactt tagttgaaac aaaagcacca gatggttatc
    23161 aattaaccaa tccacaaaaa gaaactactt ttatagtaaa aaacggaaaa ttgcaacaaa
    23221 caaccggtat catccatggc gcagatgaag ccaatcttgg gaatccaaac ggtgtagtca
    23281 atcgggaaaa tacaactacg gataacacga ttactgtaga aaatgtccaa aactacggtg
    23341 atttccactt catcaaacaa gatgtgaaca cgcaagaaaa attagccgat gcagaatttt
    23401 ctattctaag agcaaaagat ccaactgtta aattaatgaa aaaaatagca aatcttgcct
    23461 caggagaata cccatatgct tggtcagatg aagtcacagg ttctgactgg gaagaagtga
    23521 aattgatttc tgattcagaa gggaaatttt caatcgaagg gctgaaacaa ggggcatact
    23581 gccttcaaga aacaaaagca ccagaaggct acgcattacc taagaatgaa gctgcgtaca
    23641 ctgaatttac agtagatgat gatccaacaa cttctgatga aacaacgatc gataaccaac
    23701 ctaaaggaat cttgccttca actggtggta tggggatcat cgtattcatc ttggtaggta
    23761 ctgctttagt tggaggagca gtgatctact tcaaaaaacg ccatcaagaa acagaagctt
    23821 aaactattgg aaacaaaaat catacgataa ataaacgata gtgattcaaa tggggagaaa
    23881 ggttgtgaca agtggtcggt ctcttggtat tcgctcaaca aacggcaaaa taggaggaac
    23941 tattttgccg tttgttgagc gaatactcag gtcaaggcgc tgatttcaca acctcttcat
    24001 atacatatta gaaaataggt ggacatgatg aataaaagca gaataagaat actggacatc
    24061 ttcatggcaa tcattttagt cgttgggatc gggatctttt cttatccttt tgtagaagat
    24121 tcactgaatg attttcttgc ccagcaaatg atcatccatt atcaaaagca agcatcgaat
    24181 aagaattcag aggaaataaa aaaacagcag gaaaaaatga caaagaaaaa ccaacagttg
    24241 gcagagcaaa acgtatcacc agggataggc agtttcaacc aagcagttga tgcaaaagca
    24301 ttaaaagatt tacctagtaa tgcctttttt atggaacata tgcttggagt catcgaaatc
    24361 ccaaaaatca atgtcagctt acctatattc gatcagacaa cggaaatatt tttgcaaaaa
    24421 ggaacgtcat tattggaaga aagttcttat ccgactggcg ggaaaaacac ccatgccgtt
    24481 ctttctgggc atcgtggact cccagaagca aaattattta cagatttgcc taagttgaaa
    24541 aaaggagacc agtttttcat ccagatcaat ggaaagacat tggcgtatca agtagaaaaa
    24601 atccaagtgg tcttacctga tgaagtagat tctttgggta tccaaaaagg cagagatctc
    24661 gtgactttgc ttacctgtac tccttatatg gtcaatacac atcgactgct tgtgacgggg
    24721 catcgtattc cttatcaagc aaaagaggca aaaaaagcga tccaaggaat tgatcaatgg
    24781 aaaaaatgga aattttttat ttggtttatc ggtatactac ttggatcaat cggcttagtt
    24841 tggctactca tcgcttattt agattctttg gccatcgcta agcgaaacta tcctttatct
    24901 ttttatgtaa agaacacaaa cggacgacca atcgaaggaa tggtcttttc tgtaaaaacg
    24961 ctcaacggca aacactatat tactagagaa aaagttccat ttgtgaaagc ttctgatgaa
    25021 tacggactag tgagattttc tgatttaaaa ggcaggaact atcgcttgca acatgaggag
    25081 ctcctgctta aaatccatgt aaaacataaa cattcgaaac agttttcaat gaaattgaaa
    25141 aaaggaagat ataaactgcg aaaagaaaaa gaggtgtact atttgattga gaaagaatga
    25201 atgaagatgt ccaaaaaagc agagggaaca gactaaatga aaaaagagag aagctgacga
    25261 aatggacgtg taaactgcta tttttggttt actatctgga acgccagctt ctattttttt
    25321 atgtttcaga agaattttat tattatagta taacttttga attagtttcc ataacatttg
    25381 gagcaagggg ttaaaccacg agcttgagct tcgcttaaag tggcaggggt atacgtacca
    25441 tttccacatt tatgtgtatg gtattttgaa ccggtcggtg tgacatagac agtttgttca
    25501 ttattttgct caggagctgc ggcttgtgcc tgctgagagg cctgttcagc tgctgcttgc
    25561 tgtcgcgcct gttctgcttg ttgctgtgcg attgcttctt gttgcgcttg ttctgcttgt
    25621 tgtcgtgcaa tttcttcttg ctttttccgt tcttcttctg cttcttttgc tttgattgtg
    25681 gaatcaattg cagcaagacg gcttgtcaac tcttgtttgt tttcaggtag cgcttggata
    25741 gctgctgaag cagttgcata gttttctttt gtaggatttg cttcagcttg tgacaaagca
    25801 gattccgctt ctgtcacttt tttttctagt gcagcttttt ccgctttttg tttctcttct
    25861 tcttttttct tttcaatttg ttcttgttct ttcgatgaat ctgccgtact ttcggagatc
    25921 gtggtactgc tgctggaagc ctgagctgaa cttgtgcttt gagtagtaga cgtagtagca
    25981 ccacacccac tcaacaaact tcctgcgacc aaaaacaatg caactaattt tttcactaaa
    26041 tttcctcctt aagtaaaaaa caaccgtttt caataaatgt ccttttcaat tgtttactta
    26101 cttgttataa taattgtgtt atgaatagtg attgaggaaa cttaatctaa tcccgttttg
    26161 atacacggga ttttttgcta tagttctgtt attaagtatg caataataaa atatgtacgt
    26221 tattttatta ttagattatt gacatttata taataaacga ttaaatgatt catatcaata
    26281 gaatacttag gaaaaaaaga gaaataataa caggtttatg cactattgac ggtgtgacaa
    26341 tatgatattt gtatccgttt tttttcttgt atgtagtata gtaaagtaga tacaggagga
    26401 gaaaatatgc agactttttt aacaaaagtt tctcaaaaga aaattaaaat gattcattta
    26461 ctgcttgaaa cagaacgttg gtgttcaata gaagaactac aaaacgaatt gaaggtatca
    26521 agtaagtcta tcttgaatta tctaacagat ttagaagaat tgttccaaaa atatcctgat
    26581 aaggtcattt tgaagaatga gaataatcgg cgcttttcta tggaaaagca ggagaacttc
    26641 ccaatctaca ttatttatct tcatttctac agaaaatcat ataattatca tttgattgaa
    26701 ttcatgtatc aacatcctga gaaaaatttg gaagattatg cagacgctca atatacgagt
    26761 gtatccacag tttttcgtta tgctaagtta ttagtaaagt actttgaaat gacggacgtc
    26821 aaagaatagt agccgccaga tagaaggaaa ttagcagttg aaaaagctgc cctgcatcaa
    26881 gtaatacgac cagccaaacg gaaacagtgt ctcatgtttt tgatttggct ggtcttatta
    26941 ccgcagatgc aagcttttgc cacacctctt tcttgtcatt tacagactca actatcaatg
    27001 ctgcaagctt tcccttaatg ctgtaacacc agtaagagtt gtcaagacca gcagactgac
    27061 taggtaaata ccgctcaaaa acaagattac ggcagttaaa ctataatgat ccatcaagaa
    27121 accgatgacg atagaagaaa aaccaccaac agctcgtcca aggttcataa tgaaattatt
    27181 cgccgtcgcg cggatttctg ttggatacaa actactaatc actgcgccat atccaccata
    27241 catgccattg ataaagtagc cgactatcac agcggctgct accaaactcc actggctatg
    27301 ggctaacaca agtagataga cagataagga tgaacaaatt aaaaacaaag aaaaggctag
    27361 tttaggcccc aatttatcca tgattatgcc aaaagtcatc atccccaaag acatgcctaa
    27421 aatagtactg accatccaca atgaagaccc agaaaccgaa agccctaatc gattttgcat
    27481 aattgaaggc agccaattca ttaacccaaa atagccggca atttggacag ttaccatgat
    27541 actaaggcca catgtttgcc aagcaagatg ttttgattca aacagtctgc taagtttggt
    27601 tttcttttcg gcagattgta cagatttgaa ttcctttggt tcagtcaagc cgcgacgaat
    27661 gaacaagacc atcaacaccg gcagtacacc tacgacatac aacatcttcc aaccaaacgt
    27721 tggaatgatc acagcagcta aaatcgcagc caaagccgca ccgacctgcg caccaatacc
    27781 agcaaccgaa gaagctcgtc caatttgttt ttttgaaaaa ctttcggaaa tcaaggacat
    27841 acacgccccg tattctcctc ccgctcctac acctgcgata aagcgaaaga gataaaccaa
    27901 gtagatgttt gaagcaaaat acatcaataa agaagcaatc gaaaacagaa ggaccgtttg
    27961 agaaaatact ttcacacgtc catatttatc agctatgatg ccaaaaaaaa tacctccaat
    28021 gagcatcccc aaattagtga tcgttgaaat gaaacccgct tgcgtaccac taatatgaaa
    28081 agaagtaatc attgaagata atgaaaaagc taaaaacata atatccatat tctctaaagc
    28141 aattcccgcc gatgtcgata ataataactt tcgctgatac gttgtcattt ttatacccct
    28201 tttcctaaaa tttccctaaa ttgttaaaag tatatccaaa aaagaataaa aaaacaagac
    28261 ttttttattt gaaataatac acaaacaacc gatatagata atccagctta gttttaatag
    28321 aaatgagtat tgacttggag tacacttaaa gttgtagaat aaataaaata cataagtaaa
    28381 gtggcaagaa attaagagaa agagtgatca gatgaatatc aaacaagtca gtgaagaaaa
    28441 gggcatttcg gccgatacat tgcgctatta tgaacgaatc gggttgattc caccagttaa
    28501 tcggacaaaa ggcggaatcc gtgattatac agaagaagac ctaaaatggg tcgactttac
    28561 gatctgtatg cgaaatgccg gattatcgat cgagtctttg attgaatata ttcgcctatc
    28621 tagcgaagga gaagcaactg tatttgagcg gcgtaagctt ttgattgaag aaagtgaact
    28681 tttgacgaaa aaaattgctg aaatgcaaga atgtttggaa cgtttacaag gaaaaatcaa
    28741 gaaatatgat cgtgtgttat ctagaaataa aatggaatgt atcaagtaaa aaaatcaagg
    28801 agcatcgcta tggagttacg cttactaaaa tatttttgga caattgcaga agaaggaaca
    28861 atctctcaag ccgcagaagt tctacatctt acacaaccaa ccttaagccg acaactgaag
    28921 gagttagaag aggaactagg aacagaactg tttgtacgcg aaaaccgcaa aatgatcttg
    28981 acagaagcag gttattttct aaaaaagccg agcagaagaa attttagatt taacgaatca
    29041 aaccactcaa gaattcgaga acagaaaaaa acaattattc agcggccgat ttacgatcgg
    29101 ctgtgtggaa gctgataatt cgaatacatt ggcactatta ctagaaaagt tgatccgtga
    29161 ttatcccagc gttcaatttc atatccacag cggaacaagt gatgatatca cggagtgact
    29221 agaaaaaagc ctgttagatt tagcgatttt gctagatcca gtagatacag agaaatacga
    29281 aacgattttg ttaccaagaa aggaaaaatg gggattgctc attttagaaa attctgtttt
    29341 agcaaaaaaa gacgtgataa caaaagaaga ctttgcgaat gtacctcttt tgatctcaaa
    29401 gcgtccagaa atacagcgaa tgtttgctga ctggttaggc ataaaaaagg agcagttgct
    29461 gatcacagga acgtacaatt tgattttcaa tgtatttgcg ctaattgaga atcaggtagg
    29521 tgctgcttta gtcatagaag gtgctgtaag tcatctttca aagcgagtga cattcgttcc
    29581 gcttgaccca atgattgaaa cgaactgcat gctagtctgg aaaaagaatc ggattttatc
    29641 acctgtagtc aatgaattga ttcaccgttt caaagaagct tttgaacagt aataagtatc
    29701 tctaatcgaa gaaatttcaa tacaaaagcg agacgtatga cagtcttgct tttgtatttt
    29761 ttcattttta aatcaaaaaa aataaagaga tttacataac ttgttaaata agcgcttaca
    29821 aacataagaa gaacggaaat gaatcagcta taataaccgt tgttctggat tgtaatcatt
    29881 acaaagaaat gaagattata actttggagg tgttcgaaat gaaagaaaaa aagcaaaaat
    29941 tcgttcaaaa aacatgccct ttattcaatg gttgggtatg attctgctga ttgtattagc
    30001 tttattgacg atcattcctt ttttatggat ggtttctgct tcattcaaag caaataatga
    30061 agtgttcacg attccgattc aatggatccc taaaacttgg catttagaga attatctggt
    30121 tatttggtct cgtattcctt tagtgacatt ttttaagaat acagcttttt taagcgttgt
    30181 gatcacgttg attcagttgt ttacttctag ttttgctgct tacgggtttt ctaaactaaa
    30241 ttttaaaggg cgcgatattt tatttttagc atatatcggc acgattgctg tcccttggca
    30301 gtcttatatg atcccgcagt tcattatgat gagaaaagtg ggtttaacat atacgttgtg
    30361 gtcgttggtg ctattacaag cgttcaatgc ttttggtgtg ttcttgttga agcaatacta
    30421 cagtagtatc ccagattctt tatgtgagag tgcgcggatc gatggcttat cagagtgggg
    30481 aatctatcgc aagatcattt tacctcttac aaaaccggcg attgccagtt tgacgatcat
    30541 cacattcgtt aatacatgga acgattatat ggggccattc atttatttgt cttctacgga
    30601 aaataaaaca atccagttag ggttgaaaat gtttattggg ctatttgatg cagagtacgc
    30661 attaatcatg gctgcctcag ttgtttctgt tcttcctgtt gcttttatat ttttagcgat
    30721 gcaaaaatat tttgtagaag ggatcgcttc atcaggaatg aaggaatagg aggtgattat
    30781 gaaagagcag cgttttgaca aaaatgttta tatggaattc ttttattggt tgtatcaatc
    30841 attggcaagt agcctttgtt tttggtgtgt caatatcttg tatatagcag ctgcgttcct
    30901 tttgtcgata gatggaagga atgtcttttc ctttattttt tctttacttt ttattggtcc
    30961 aggttgcatc gtgatgatag gtatgacaga agaattagca aaagaaaaaa gtttttcacc
    31021 agtacgtttg ttcataaaga cgtttcgcca attttggcta aagggatttt tttattggct
    31081 atttgcttgg atagttagtg tgataatgat ttttgattgt ttctttttta tacgtttttc
    31141 ttatggaaaa tggttgattc cgttgtttgt tttacttgct tgtttatcag tttcctttag
    31201 catcaactac tggtattttc aggtgagaaa tccagcgtcg aaaccaaatc aagttctacg
    31261 gatagcgttc tactatacgt tgaaaaaatg gtatgtgagt ttactagatt ttttactatt
    31321 gacaagtttg tttctcttct ttttcgtaaa gccccaatgg tgtattctac taggtccttc
    31381 tatcgtattt ggtttgattt acttcaacaa tcgtaaattg atgagaacta tggatctgta
    31441 gactttataa attgaaactt tcaattaaga atgacagttt ttatgtaaaa actgtcattc
    31501 tttttcattt tttgaaacat atggctaaac aaatgaaata aaacgtgcta tacttttgaa
    31561 tgaaacaggt ttagaaactg tatcaattat ttgtgattat ttctaactaa taattaaaaa
    31621 taaagcataa aaaggacgat gttcaatgga cgaaaaaatg aaacaaggtt cgaaatctgt
    31681 agtagaaagt ttgattaatc atcatgttga ttatgtattc ggtataccag gtgcaaaaat
    31741 cgatggtgta tttaatgaat tagaggatca aggtcctgaa ttaatcgtga ctcgtcacga
    31801 acaaaatgct gcatttatgg cacaagcaat cggacgtatt acaggagagc caggagtagt
    31861 tatcgcaaca agtggtcctg gtgctagtaa cttagctaca ggtttggtaa cagcgacagc
    31921 agaaggtgac ccagttttag caattgccgg acaagtaaaa cgaagcgatc tattgaagtt
    31981 gacccatcaa agcatggata atgcagcact gttccagcca atcacaaaat acagtgcaga
    32041 aatccaagat ccagaaacaa tttcagaagt gattgccaat gcttatcgta tggctaagag
    32101 ttcaaaaaaa ggcgcgagct ttatcagtat cccgcaagat gtagtggatg cacctgtcca
    32161 agggaatgtc atcaagccat tgagcgatcc taaattaggt tctgcttctg cagatgatat
    32221 ccgttaccta gctgaacgca ttagagaagc aaaactaccg gtactattag taggtatgcg
    32281 aggatcaagt gaaaaagaaa cgttagccat caggcaatta gttggaaaga cagcattgcc
    32341 tgttgtagag acattccaag cagctggagt gatctcacgt gaattagaag cgcatttctt
    32401 tggtcgtgtg ggtttattta gaaaccaacc aggagatatg cttttgaaac gaagtgatct
    32461 agttattgct attggctatg atccaatcga atatgaagca agaaactgga atgcggaaaa
    32521 agatgcgcgg atcattgtga tcgatgaagc gccagctgaa atcgatcctt ttatgcagcc
    32581 tgaaagagaa ttgatcggtg atatctcagc cactcttgat ttattgacag gttcattaga
    32641 gcctcaacaa gtgtcagaag atgcaaaaga atatttagca tctcttcaag cagaattaac
    32701 ggagcgggac attgttcaat caaaaggaga agcaggtatc ttgcatcctt tagaagttat
    32761 taacacgctt cagtcaaaag taacagatga tatgactgtt accgtagatg taggtagtca
    32821 ttatatttgg atggcacgcc actttagaag ttatgaacct cgtcatttgt tattcagtaa
    32881 tggtatgcaa acgcttggtg ttgcattgcc atgggcgatt tctgctgcat tggtgcgtcc
    32941 aaatacacaa atcgtatcag tttccggcga tgggggattt ttattctctg cccaggattt
    33001 agaaacggcg gtacgtaaaa aattgaatat cgttcatttg atttggaatg atggacacta
    33061 caatatggta gagttccaag aaaaaatgaa atatcagcgg gcgtcaggtg tagactttgg
    33121 tccagttgat tttgtgaaat atgcagaagc ttttggcgct aaaggaatcc gagctacaag
    33181 tgtagaggaa ttagaaaaag ctttagaaga aggatttgcg acagaaggac ccgtaattat
    33241 tgatattccg attgattacc gtgataatga gaaattggga gaaacaatct taccagatca
    33301 attctattaa ggaagtgtcg acatgactga aaaaatctta taccagcacg ggacattagg
    33361 agctttgatg gctggcttga tggatggaac agaaacgatt gctcatatat tagaaaaagg
    33421 aactctggga ttgggaacat tgcatgggct tgatggtgaa gtcatctttt tagatggcgt
    33481 agcttatcaa ggaagatcag atggctcagt tgcccaatta gatggaagtg aacttacccc
    33541 ctatgcagca attacagatt ttacgccaga tactagtttt tctgtctcaa aaactgcaga
    33601 tggagaacaa ttgaaaaaag acatattagt aagagaagcc ggggaaaacc tatttttggc
    33661 agtgaagata actggattat tcaaaaatat gcacatccgt atcatgccga agcaagaaaa
    33721 accttacaga agactagcaa aaatttcaga gtctcaacca gaattccaac aaagcaatgt
    33781 ccaaggaaca ttagtcgggt tctttacgcc tgaattattc caaggagttg ctgcagcggg
    33841 atttcacttg cattttatcg atgatacaca tacatttggc ggacatgtaa tggattttga
    33901 agtggctgaa ggaaaagttg agattagccg catctcgtcc cttgtacagc attttccagt
    33961 tgatgatccg acttttgttc acgaaacgat tgattatgct gatttagcag cagaaatcca
    34021 acaagcagaa tagaaaaaga cagcgagatg cgttcaaggt gattaacctg acgtatctcg
    34081 tttttttgag gaggaaacct agcgtttaca aaaaaactga gctataatct tctccataga
    34141 tcaaaaagga gcggttttta tcatgtggac agaaaaacag aaaaaagatg catacgaaat
    34201 tttattatta cagcaacaag gattattaga agcagaagat aactggttag caaatttagc
    34261 aaattcatct gcattgttga atgagacttt gcctgagact gtctttgcag gatattattt
    34321 attcgatggt aatgaattga ttttaggacc gttccaaggg cgagtttctt gcacacgtat
    34381 caagatggga aaaggagttt gtggagaatc agctgaaaaa caagaaacat tgatcgttga
    34441 tgatgtcaaa acccatgcaa attacatttc ctgcgattca gccgcacaat cagaaatcgt
    34501 agtgccaatg gtaaaagaag gtaatttaat cggtgtttta gatatcgatt gcggagtaac
    34561 gaaagggtat gatgaaatcg atcaagcatt tctagaaaaa tatgtagatc ttttattagc
    34621 aaattttaat ataaatgctt tttcatttat taataactaa aatcgtctat tgaaacaaaa
    34681 aagaagagaa atcaagaata aaaagagccg gaaagacagt gggcatttct gtttttcggt
    34741 ttttttattt ttttataaaa tcacaagtgt tattgatttt cataatcata ttttaatggt
    34801 attatcattt taaataatgg aaaaacatta aggatggatg aaatatgaat aacgaaacta
    34861 tcattttagg aaaaaaatat atttgccaac ctattggctt gaaacaaaaa gtggttggag
    34921 aagtaatcag taaattagaa aattgtgttg tgatctgcgt agacgaatat catgacgtcg
    34981 atcgcaatga aatattagaa aaatgcggaa aagtagtggc aaaatatact cacgtttatg
    35041 agttggaaac aacagaatat ctatataact atagcaacaa atatgaacat actttagttt
    35101 cataaagatt taaataaagt gccttcaaaa gcgagaagac caagcttttg aaggcacttt
    35161 atttagttgg cagtgattgt tcatgatttt tgatttattc aaaaggttcg cctagagaat
    35221 ctgtctctgt aacgaggcct ggtggagaaa ctcgataaaa acctatactg ccagaactgt
    35281 cctattttcg gatagacaaa ctagtagttt taaaaagatc atccgatcca atcatttcaa
    35341 aaaatgcaaa actgatatca ggatcattta gctcaggctt gttatcgtaa agcatttgta
    35401 aaggttgcat ttagttagga gtaaacgcga aactatcatc attatttgct gaagaagatg
    35461 aagaagctaa ttcagagttt gtttgaaata aaggagacgt gctgacagtt tctttaccct
    35521 gttttttgca gaggtagaaa cttttatatc ggaagtttct accggagaat ttttctcatt
    35581 tgtagaaatt gttgaatcga tactattcga aatttgcgta tctgaaggta tgttctttga
    35641 tgcagaagtc ccacaagcag taagtaacaa taaatttgat aaactgataa acagaattct
    35701 tttcattatg tacacactcc ttatagtatc gtttagcata cacctatgct cagtattagg
    35761 caaaatcaat gcaaaactat caagtctttt atagtatcta ttagtcttag taatacatat
    35821 atggagaggg tgatatccca gttcaaacca gatacattgg ttaccatctg tattaacgat
    35881 tatgcctcta aacgcttttt ttatgaaaaa atttataagt gaaaacgtag gtatgatatt
    35941 atctagaggt aatttttttg ggtatttaaa tagttgctag gaggatag
//
LOCUS       DACDLM010000024        35848 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.024, whole genome shotgun sequence.
ACCESSION   DACDLM010000024 DACDLM010000000
VERSION     DACDLM010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35848
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.024"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(176..2347)
                     /gene="copB"
                     /locus_tag="IV356_001228"
     CDS             complement(176..2347)
                     /gene="copB"
                     /locus_tag="IV356_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HAP9014929.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(2367..4553)
                     /locus_tag="IV356_001229"
     CDS             complement(2367..4553)
                     /locus_tag="IV356_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HAP9014930.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(4553..4762)
                     /gene="copZ"
                     /locus_tag="IV356_001230"
     CDS             complement(4553..4762)
                     /gene="copZ"
                     /locus_tag="IV356_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HAP9014931.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(4775..5215)
                     /locus_tag="IV356_001231"
     CDS             complement(4775..5215)
                     /locus_tag="IV356_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HAP9014932.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(5289..5828)
                     /locus_tag="IV356_001232"
     CDS             complement(5289..5828)
                     /locus_tag="IV356_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HAP9014933.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            complement(6443..7909)
                     /locus_tag="IV356_001233"
     CDS             complement(6443..7909)
                     /locus_tag="IV356_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP9014934.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(8220..10301)
                     /gene="cadA"
                     /locus_tag="IV356_001234"
     CDS             complement(8220..10301)
                     /gene="cadA"
                     /locus_tag="IV356_001234"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAP9014935.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            complement(10825..11184)
                     /locus_tag="IV356_001235"
     CDS             complement(10825..11184)
                     /locus_tag="IV356_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HAP9014936.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(11214..11555)
                     /locus_tag="IV356_001236"
     CDS             complement(11214..11555)
                     /locus_tag="IV356_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014937.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            complement(11552..12226)
                     /locus_tag="IV356_001237"
     CDS             complement(11552..12226)
                     /locus_tag="IV356_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAP9014938.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(13279..14577)
                     /gene="asnS"
                     /locus_tag="IV356_001238"
     CDS             complement(13279..14577)
                     /gene="asnS"
                     /locus_tag="IV356_001238"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HAP9014939.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(14617..15807)
                     /locus_tag="IV356_001239"
     CDS             complement(14617..15807)
                     /locus_tag="IV356_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAP9014940.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIETIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYSLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(15828..16355)
                     /locus_tag="IV356_001240"
     CDS             complement(15828..16355)
                     /locus_tag="IV356_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAP9014941.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(16402..19191)
                     /locus_tag="IV356_001241"
     CDS             complement(16402..19191)
                     /locus_tag="IV356_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAP9014942.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(19338..19538)
                     /locus_tag="IV356_001242"
     CDS             complement(19338..19538)
                     /locus_tag="IV356_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP9014943.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(19990..20310)
                     /locus_tag="IV356_001243"
                     /pseudo
     CDS             complement(19990..20310)
                     /locus_tag="IV356_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(20813..21931)
                     /locus_tag="IV356_001244"
     CDS             complement(20813..21931)
                     /locus_tag="IV356_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014944.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYYEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAIFRY"
     gene            22401..23708
                     /locus_tag="IV356_001245"
     CDS             22401..23708
                     /locus_tag="IV356_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HAP9014945.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSESKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANMFVIGWRRVAEFFGNLF"
     gene            23827..25025
                     /locus_tag="IV356_001246"
                     /pseudo
     CDS             23827..25025
                     /locus_tag="IV356_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(25052..26320)
                     /locus_tag="IV356_001247"
     CDS             complement(25052..26320)
                     /locus_tag="IV356_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HAP9014946.1"
                     /translation="MEKQLPSTVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKAEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     gene            complement(26483..27130)
                     /locus_tag="IV356_001248"
     CDS             complement(26483..27130)
                     /locus_tag="IV356_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HAP9014947.1"
                     /translation="MEQTIKPYQYFFIKREVEQLLNAYSSVNDPKTVQTVQALAAEKI
                     RDILDHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(27538..28041)
                     /locus_tag="IV356_001249"
     CDS             complement(27538..28041)
                     /locus_tag="IV356_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP9014948.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(28164..28928)
                     /locus_tag="IV356_001250"
     CDS             complement(28164..28928)
                     /locus_tag="IV356_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HAP9014949.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DVEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSK
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLAEVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            29036..29311
                     /locus_tag="IV356_001251"
     CDS             29036..29311
                     /locus_tag="IV356_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HAP9014950.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            29907..30857
                     /gene="yidC"
                     /locus_tag="IV356_001252"
     CDS             29907..30857
                     /gene="yidC"
                     /locus_tag="IV356_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAP9014951.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPADNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(31036..32010)
                     /gene="lacD"
                     /locus_tag="IV356_001253"
     CDS             complement(31036..32010)
                     /gene="lacD"
                     /locus_tag="IV356_001253"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAP9014952.1"
                     /translation="MKKMSIEKQECLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPEYGLPAAALREKECGLLLAYEKTGYDAKMPGR
                     LPDLLNSWSVKRLKEVGADACKFLLYYDVDESVEINVQKQIVIERIDSECEAEGMPFF
                     LEILSYDATISDPSSLAYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVKGYG
                     QETCYSQAEASTYFYEQSKVTEQPFIFFSAGVSAALFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLEETATPVYVDR"
     gene            complement(32007..32465)
                     /locus_tag="IV356_001254"
     CDS             complement(32007..32465)
                     /locus_tag="IV356_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAP9014953.1"
                     /translation="MTIIHEENIFLQQPLDSQEEAFKFLAKQTFCLGIAHDEKEVYRK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSLIIVTLNKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRAAKSKTEIATILTKEIGEDI"
     gene            complement(32462..33925)
                     /locus_tag="IV356_001255"
     CDS             complement(32462..33925)
                     /locus_tag="IV356_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP9014954.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEGLEQAARKKGITIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFAGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTILADNEAVDTLESETISGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSFDPDHAQYNATAAMLKTVGDAAMGMMVPVLAAYIAEGIAKRPGLVVGFVGGIVAM
                     SGGTGFLGGILAGFLAGYFILFLQKLLTILPKQLDGLKAIFLYPVIGVVFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEHSNPLVLGVIVGCMCAFDMGGPINKAAYVTGTALLAQGN
                     TTFMAGVSVACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKMDNKAANRTVIEEGRAGGLS"
     gene            complement(33907..34857)
                     /gene="pfkB"
                     /locus_tag="IV356_001256"
     CDS             complement(33907..34857)
                     /gene="pfkB"
                     /locus_tag="IV356_001256"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010779385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAP9014955.1"
                     /translation="MSIYTCTMNLAIDLFIETEEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQKKQIQTEFIEVPGMTRINVFTQVNQTREE
                     YKLVNQGPEIPQAAVHNFLNQIRALQAEDYLCVSGSLPRGMSPKVLVEISRICQEKEI
                     HLIIDSSDQEVMGCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVESGAENV
                     LLSLGEKGAILFTKDRVIRGNSPKGKVVNTACAGDAMLGTFLVGYMNRRPLDETLRKS
                     IAAGSSTAFRKGLTDFLDVEELSKQIKIKEERFERWENIN"
     gene            35000..35749
                     /locus_tag="IV356_001257"
     CDS             35000..35749
                     /locus_tag="IV356_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP9014956.1"
                     /translation="MDHKLSETEQYLWNFIEHHILEIPNYSIVKLSEQANVSTATIVR
                     TMKKKGYEGFTSFKHHLKEGENKNINFSFLDKVDKGIRRAILKNEQEVVRTINMLEIG
                     NIEDAIQRIKFTDRVFVFARGFSEMIGQEMLVKLQLTGKNCQMHTDPEIIKSISRKLT
                     KKDSVIFVSLNGETKELVTAAKNCYDAEIGSILVTANHSSTLKDYCEINLVGFKSEGS
                     YFPDYEVRSRLPLQIIARILLDAYVLRMREN"
BASE COUNT        10261 a         7702 c         6255 g        11630 t
ORIGIN      
        1 gagtatccta cggatttaaa tcatttgaga acatgagaat tagaatcttt ttgatcaatc
       61 aattaatcaa agtaagataa caaaaaatct gagccagaat gaggttcatt ctgacccaga
      121 tttgattttg tacaacccat cagtccttat tgacaaagag cccctttttt cattattatt
      181 tgattttcaa tgtcaaagca tttagagcta caactaccgt acttaacgac atcaagacag
      241 caccaactgc tggacttaat atgataccaa ttggcgcaag aattccggct gctagcggaa
      301 ttgcaagaat attgtaacct gccccccacc agaggttctg gatcattttc tttcgcgttt
      361 gcttggctag atcaagaaaa tgcaaaatat cttttggatc gctgtttgtc aatacgacat
      421 ccgcagaatc gattgcgata tctgtccctg caccgattgc catcccgatt gaagcacggg
      481 ctaaacttgg cgcatcattg atcccatcac ccaccatgat tacttttttc ccttggtcaa
      541 ggtatttctg gacaacagct tctttatcat ctggtaataa accgccataa tattcttcga
      601 tccctaaata atctgctact gcttgggcag cgtttttatt gtcaccagta agcatgacag
      661 gagtgatttt tctttctttc aatgttcgga taaattcttt tgcttctgtt tttactacgt
      721 cacctaaagc aacgattgca gctagatgat tttctaaaat caggaagctg atggtatttc
      781 cttgttcttg gtaaggtttc aataatgctt gttctacgtt taatccgaga cgctcaactt
      841 ctttttcatt aactattttc acttgttgtt ttttgactgt tgcctctagc ccgactcctg
      901 aaagattttt tagattttca gcttgataag gcttgatttc atgttctttc aaataattca
      961 taatgccaac agccaatgga tgattggcat tcgcttccaa ggctcctaga tattgaagga
     1021 tttcattttt attgaacgca tcatcaagta cttcgacacc cgttacagta aattttcctt
     1081 ctgttagtgt tcctgttttg tccagcatga tcacatctag atcattggct tgctccagtg
     1141 cattgcggtt tttcaaaagt aatccgtttt tagctgctat tgatgtggag cgagcaacaa
     1201 ctaatgggat agctaaacct agagcatgag gacaggcgat gataaagact gttaccatac
     1261 gttctaatgc attaggaaga tctgtcaaga acaaccaggc gatgaatgcc aggataccca
     1321 caattaatgc gacataaaac agccattttg ccactttgtc agataatgac tctagcttgg
     1381 atttttctcc ttgtgctttt cgcaccattt ccataacctt cgctagataa ccattttcac
     1441 cagttccagt tacttcgatt tcgatcgttc catccccatt gatagaaccg ccaatcactt
     1501 tgtcattggc ttgttttttg attcctcttg attcgccagt cacagctgat tcgtcaacaa
     1561 ttgtttcacc tttcaagatt acaccatctg ttggcatttt atcaccagac cggacgatca
     1621 aacgatcacc ttcgtttact tctttcaatg aaactgtctc ttcttttcca tctttcgtca
     1681 agcgtttcac tgattctggc agtaattctg ctagtttttg taaagcattg ctggcattcg
     1741 acacagcatt catttcaatc cagtgaccta gtagcataat aacgatcaaa gtagccaatt
     1801 cccagaagaa atccatgacg tgtgtatgtg gattgagcag atttgcgata aacgaataga
     1861 cactataaat atatgcaact gtaatcccca tcgcgatcag tgtcatcata gcaggacttt
     1921 tttgtttcaa ttccatctta gctccactta aaaatggctg accgccatag ataaatagta
     1981 tagttgctaa gatcaatacg agccaatcag aaccaggaaa cgttacttga aatggaaatt
     2041 ccattcccat cattggtgaa aaaagaatga ttgggatagc taggataagc gatagccaaa
     2101 atttttgttt gaaattcccc atgtgcatgg aatgatccat gccgccgtgt tcgtgatcca
     2161 tgtgcatcga atggtccatt tgtttgctgt ttgctatatc tccatggtta tgtcccatgt
     2221 gcatggaatg atccatctga ctatggtcat gtttcatctc catctgtttt tcatgagatt
     2281 ctgtactttc tttgtttact acttcttttt tatgctcatg ttttttctcc atatcgttcc
     2341 cattcatttt tactccatcc cttctcttac tttttcatgt gtcgatttaa gctcagggag
     2401 ttcaacaata cactgacgga actaaacgcc atcgctcctc ctgcaatgat tggattcaaa
     2461 aagcctagtg cggcaaaagg aataccaatc gtattataga caaaagccca gaaaagattt
     2521 tgtttgattt ttctcaatgt caacctagac aactcgattg tttgtgcaat ggatgccaaa
     2581 ctgctattca tcagcgtcac atcggctgtt tccatcgcaa tgtccgttcc acttcccatt
     2641 gccataccga catcagctaa tgctaaggcc ggtgcatcat tgattccatc gcctgccata
     2701 ccgacttttt tgccatcttt ctgaagtttt tctacgtagg ctgctttatc ctctggaagt
     2761 acttcagcaa agatatgctt tggatcaata ccaacttgtt taccaatcgt ttcggctgcc
     2821 agtttgttgt ctcctgtcag cataaaaaca tctaatcctt tattctggag ctgcttgatt
     2881 gcttgtttgg cttctagttt gatttgatca gccacggcaa tccacccgat cacttgcttt
     2941 tcatcagcta aaaacatgac tgtttttccc tgctgttcta attctaacgc gtgttcttgg
     3001 tattcatcaa atgataggtt caattcaatt aatcgtttac gtgtacccgc aaaatagcgt
     3061 actccattaa tcgtaccgct gatcccagca cctgggtggg ctgtaaaatc aatcatatcg
     3121 tatgttgctg cttcttgcag ttttccgtat tccacgattg ctttacctag tggatgttca
     3181 gaagcttgtt ctaaagtata aaaaatagat aggacttctt ttgaaccgac tagatctgta
     3241 actttgggct ttccttctgt aatcgttcca gttttatcca aaacaatgct gtctaagtga
     3301 gcagctgctt ctaatgcttc tccgccttta attaaaattc catttcgtgc accaacaccc
     3361 gttcctacca taatagctgt tggggtcgct aaacctaatg cacatggaca cgcaatgact
     3421 aatacagaga cactatggat caatgcgagt tgccaatcac cagtgatcaa acctgtagct
     3481 atgagcgtga taaacgcgat gactaatacg atcggaacaa aaatccctga gatccgatct
     3541 gcgatttttt ggattggggc tttgctccct tgagcatctt ccaccatttg aatgatttgc
     3601 gctaatactg tctgcttgcc gacttgtgtg acttccatgt gtagcagacc attcgtattg
     3661 attgtcccgc caaaaagcgt gtcatccgga ttcttttcta caggaagatt ttcaccagta
     3721 agcatacttt catctatcgc actgcttcct gaaataattc gaccatctgc tggaatctgc
     3781 tcaccaggac ggatgactag ttgatcacca acgactactt cttcaatcgc taacgtttct
     3841 tctttcccgt ttcttatcac ttgggcggtt tttgtttgaa gagacatcaa ttgtttgatt
     3901 gcattacctg ttttcgtttt tgctgtatgt tccaaatatt tgccgagcaa aatcagcgtg
     3961 atgatcatac tgctgctttc aaaataaaga tcttgggggt gtccacggaa aaatccgttg
     4021 taaatgctca atgcaaaggc agccgatgtt ccaattgcta ccaatacatc catatttggt
     4081 gctttcgtct tgattgcatg gtacgcacct ttataaaaac gagcaccgac ataaaattgg
     4141 acaggagcag acagcactaa ctggacgatt ggaaaatgaa aaaagtgaac aatcgccgca
     4201 tggcttccta acatcatagc aatcattgac aacatcaacg gcaaagtcaa aaccgtactc
     4261 aatataagat cgaatagcat ttttttcaaa tacgcttgct tttcttctgc aattttttgt
     4321 ttgtgggctt catcgtacaa aattgcacca taaccgatgt tttctacgct ttggattaat
     4381 ttttcagtgg tcgtcccttc atatttgaca cttgcttttt cagtggccaa gttgactgtg
     4441 gcattgacca caccaggttg tccgttcagc tctttttcga tcctagcaga acaatttgca
     4501 caagtcatac ctgtaatgac gaacgtatcc attttggttt ctgctgttgc catcaaatca
     4561 cctctgcttt ataacccaat ccattgattg cttgacaaat cttttcggat tgaacttttg
     4621 tttcatcaaa cttgaccgta ccgtttgctt ttttcaaatt tactttcact ttttgcacgc
     4681 cgtcaagtgc gcttactgtt tcttctactc ttgctgcaca atgattgcag ctcatacctt
     4741 cgattgaaaa ttgttgtttc attttttctt cctcctattg atgttgttta cattcacatt
     4801 gacctgggat acagttacat tcgatcgtat ctactggttg cttttgttcc agttgtttca
     4861 aaatctcatt gatatcttct tgagtcaaag tggcttcttc tactagatcc gcaatcgtct
     4921 ctccaatcct ttttgcacag atatgggaaa aaagattttc cgtcgcactg cgaactgttt
     4981 ccatctccga gacagctgga tgataaatga atttttttcc ttcttgttct gtccagatca
     5041 cttctttttt taccaaacgt cccagcaaag ttttgatcgt tgctggtttc caatccatcg
     5101 aatcagctaa gatctgcgtg atttcttggg ctgtcgtctg tccaagtgtc caaataacac
     5161 gcatgatctc ccactctgaa tcactgatct ttactggcgt tttgactttt tccatttatt
     5221 tcacaccttt cgtttacaaa tgtaatcatt agcttatgaa tacagattac gcttgtaaac
     5281 aaaaactgtc aattattttt gctctctatt ttcaatttag ttaaaaattc ttgtttctct
     5341 cgtcttgttt taaggatgat cagtttattt cttgcattag ctacttggat cagctgctgt
     5401 attttcggtt cattgttttc ttcaaaatgc cagataaaag ataaaaattc taagtattcc
     5461 ctgtttagtt tctctgaaaa tgattcaggc atatctggcc gagatttttt gtttatcttt
     5521 ctttttagag aacgccaaac tactcggtag atggcgagat aacgcggcac tttaagccaa
     5581 atgatcttat ctgcttcttt aatcctttcc tctaatgtag aagtataatt tccttcaaca
     5641 atccatgacg gattagatac cataaacgat tgctgttctt gcaaaaacca cttttttgcc
     5701 tgaatactgt agtctgttgt atgccataaa aggtctagcg gcagtagcgg aaagtcggtg
     5761 atttctttga tcttccttgc gagggtcgat tttcccgacc cactttgtcc aatcacgatg
     5821 atcttcattc ttctccctca cttctctttg gaatttggtt cgatcatacc acttataacg
     5881 ccgcaaaaaa acaagggact gtgacaaaag tcgtgtcaaa gtcccttgtt tcgaataaat
     5941 ggtgttcaat cagctgacct tcagcattaa ctcaaaaaac ggcaaaatat gaggagctat
     6001 tttttcgttt gttcctctaa tactcaggtc aaatcgctga ttttacaacc tcttccttaa
     6061 acggtgttct cctgccaaca cctcggtcac aaggcacaat agtcaacaaa catgagaagt
     6121 tgttttttga aattgctcct tgtgactcgg agttaaacgg caggctcact acctctttct
     6181 taaacggtgt tcaaaagctt gcatctgcgg taataagccc agcaaaacga aaaatatgag
     6241 gggctatttt tgtttggctg ttcttattac ttgatgcagg acagcttttt cacaacctct
     6301 gattcacggt gttccagaag tagcttctgc gaaaaacaag ccgaaacttc acaaaaattt
     6361 gagaagcaat tttcgtaaat tccttcttat ttcttgaagc tgaccacttc tgtcacaacc
     6421 tcttgtaaca agtatttcta ttttaaggct gaaccactgt ttctggttca gtgatttctt
     6481 tgtttttgtc tcgacgagca attgctggca agatcatacc taataagatc aagacaattg
     6541 gtgtgatgat attcgtgaat aattggaacc accatgcttt aggatcagca gtataatcta
     6601 cttttggcac cattcctagg atacatgcaa acgcagtgaa ggcaaagcac caagcaccaa
     6661 agataaaacc gatttttgga tttttaacaa atttatattc agaattgaat ttcttataag
     6721 ctttattcaa catcatatat gccaagaaca cccataggta acgcattggc atgacaactg
     6781 agttcaagtt cgtcaaccat tttactaatt cattcatatc tttgatacca aagatcggca
     6841 acaaaataat gattcctact agtatacctg tcagaagata accattcacc aatgtacctt
     6901 tacgattacg tttacgtagc cagtttggta caaattctgg atccgcatct gctaacaaga
     6961 tttttagtgg tgcatcaatt gaaaaggcta atgcggagat ttgtccaatc atgtttgtca
     7021 atgcgtaaat gatcatcaat gagttaccga taccatagta attacctaaa atttgaaaag
     7081 cactgtatgc cccatttgcc atcaagtctt taggaatatt atcgctagca aacagcatac
     7141 ccattgcgac tgagcctaat acagcacaaa tccctaccat tgctgctaag aagatcatcc
     7201 ctttaggaaa ttcctttgca ggatttcttg tagagttgac ataaggggat attttttccg
     7261 ctcctccaac tgcaaatact agcatcgaaa cggttgtgaa ataactgaaa tcaaatgttg
     7321 gaatatatgt tttcacttga ttcatatgtg gtgtggcaaa ttccatcgtt ggattgatga
     7381 acggtgccgt tacagctaaa agaataaata agatcgacat gacgaacatc gctgttccgg
     7441 ccagtccgcc aatcactttc aaagtagaaa gtccttttgt tgataaatat aaaaaggcaa
     7501 gaaatataat aagtgaaata actgctacca tttgtactga catcgtattt acgatatttc
     7561 catttccttg gactgcccaa ccgccagcaa tcaggattgc ttgaggcttt tgtgccaaat
     7621 aaggaatatg gacgacccag taagtccaag cggcatagta tgccagtcgt ttattagatg
     7681 tcgtattttc gacccatgaa ctgacgcctc ctttactatc cttgaaggct gaccctaatt
     7741 gtccaacgat caatgcgtat ggaataaaat aaatggccaa aatcaatagc caagaggtga
     7801 caactgatac tccttgctga gcatagttat taactacatt ccccatgccc caaaccatgt
     7861 taaatgcaat taacgcaaca gtaaaccagc gtaattgttt gttgttcatt cgttctctcc
     7921 tttatgataa aaatttgtta tccagatgta atcatattca atttttaaca aacttacaag
     7981 acagtgttat tttatgtgtg tattctttta tttaatacac atcgtttttt catatttttt
     8041 ccatcaaaaa aataagttat tttcttttat ttcatttacc ttattgaatt tcaagctatt
     8101 ttgaattttc tgcaaaatta aaaacattag ttattttata atcctatcta ttttctttac
     8161 atttttcatt aagaaaagga tataaaaaaa agaggacgtt cattcgtcct cttcattgat
     8221 caacgtttat tttttacatg caagcttcgc atggcattca aaacagctaa tactgtcacc
     8281 ccaacatctg caaatactgc atctcccatt gatgcaaaac caaaagcacc taaggcaagt
     8341 accaaaattt ttatcccaat agcaaagaca atgttctgtt tgacgatttt caatgttttc
     8401 tttgctaaat ggattgcttc tgcaatcttc gatggttgat cattcatgat gactacatct
     8461 gctgcttcaa ttgcagcatc gcttcccaat ccacccattg cgattcctac atctgctctt
     8521 gctagcaccg gtgcatcgtt gattccatct ccgacaaatg cggtcttttt attgtttctt
     8581 tgtaagattt cctctaaccg ctgcacttta tcttctggaa gcaattcgct atatatcttg
     8641 tccacgccta cttgcttccc gatatgatca gcaatttttt tcgaatcgcc cgtcaacatg
     8701 actgtgttct tcacaccagc cttttttaat tgaaccaatg cgtctacggc atcttctttc
     8761 aaggtatctg caataacaag ataaccactg taactttgat cgatcgctag ataaagcaat
     8821 gtaccgattt cttgacttga aggaaaagag atttcaaatc tttccatcaa tttgtgatta
     8881 cctgctaata cttgtttgcc atcaacttca gctaagatcc cttcacctgc aaattcttgg
     8941 atattagctg ttggtaaaag cggacctgcg tagccttcta aaacagattg agcaatcgga
     9001 tgtgtagaaa actgttctgc actcgcaaca tattgcatga atatctttgg atcgattttt
     9061 gtatcgatcg tctggatcga aaagtcacct ttcgttaatg tgccggtttt atcgaatacc
     9121 actgtctcag tttgtgcaag caactccaag taatttgaac cttttactaa tacaccgatt
     9181 ttacttgctc ctccgatacc gccaaagaaa ctaaggggta cggagatcac taatgcacat
     9241 ggacatgaga tcactaaaaa tgtcaatgct cgatagatcc attcagaaaa cgccgctcca
     9301 gaaacaacaa gtggaggtaa aacagctaat aaaacggcca atcctacaac gactggtgtg
     9361 taatagcgcg cgaatttagt aatgaaattt tcagctggtg cttttttact gctggcattt
     9421 tctactaatt ctaataattt gctgatagta gaattttcat aagatttttc tacttgaact
     9481 aaaaatggtt tatttttatt gataaatcca cttaatactg tttcaccaac atatacagat
     9541 ttagggactg attctcctgt aagtgctgac gtatcgacta atgattctcc ttcgatgatc
     9601 gttccatcta acggtacacg ttcaccaggc ttcacaagta caaactgacc gatctgcacg
     9661 tcttcagggt tcacggtcat caatccttcc gtcgtctgca cgtgagctgt ttctggacgg
     9721 atcgccatca attcgcgaat cgattttctt gaatgactga ctgccaatcc ttggaaatac
     9781 tcgccgattt gataaaatag catcactgct acggcttctg gatattcacc gatcaacata
     9841 gcgccaatcg tagcaacaga cataagaaaa ttctcatcaa agatttttcc tttgacgata
     9901 ttcatcactg ccttcttcac tacatcatat cctatcagca gataaatcaa taaataccct
     9961 atcaagcgaa ttggttcatt aaaatcaaat aatagcaata aagcgatacc tgcaagggaa
    10021 aataaaatcc ggaacagcgt atttctctct ttttcatttc catgttcaga tactttttcc
    10081 ttatctattt ctgttacttt gacatctggt tctaattcct tcactacttt ttttatttct
    10141 tgttcaatcg tagccaaatg atcttcctct gcgtcaatcg ttagttttcc agaagtgaag
    10201 tttaccgttg cttccttgac tccattgatc ttctgaactc ctttttcgat tttcattgca
    10261 cagttcgcac aatctaaacc ttctaatctg taacttttca ttttaatgac ctcctcgcct
    10321 caacatatga atatctcttc ataactaatt ataaatgaac ggttattcat atgtcaaggt
    10381 atccgaaaga aaaaatgaaa aacatctgca tcggaaaatt tcttccatac agatgttttg
    10441 gcttattctt tctttttctt ttcgatcatt gccactgctc ttatccaacc cgcacttgcc
    10501 ttcttgatct tgacaggata gcaactaagt ttgaagcctg ttgctggcaa tttgtctaaa
    10561 ttcattaatt tttcgatagg acaatatctt ttttcaatcc ctgcaaaatg tccttcccag
    10621 atattcgaag ctccactacg ctttcaaaaa tatagaaaga gttctttaat gaaaattatt
    10681 tcaactttcc ataaacagta accccatata aataaaagac gtaaaagtca catggaagaa
    10741 cttatacagg agaacgcata gagtcaggtg aaatacatgt atcccacctg actctatgct
    10801 ttatctaacc tttattattc tcttttatac aatttctgca ccgaatggca tcaacgccaa
    10861 tcgagcaagt ttgaaagatt gcttggcaaa aggtatccct atgatcgtga tacatagaag
    10921 gatgccgctg acgacatgtg cgagagcaat tggtaggcct gaaacgatca gccagatgat
    10981 attaacaatc aatgacatgc cagactggtg ataaattact tctttgccaa aaggcgcaaa
    11041 agaaagggag gcgatcttaa aacattgcat accgattggg atacctatga tcgtgataca
    11101 ccaaagtatc cccgctgcta accagctaag accaccgatt agtccgccga atataaacca
    11161 gatgacattt cctaaacaac tcattgtatt tctccttcta ttactgtttt tgattaaaac
    11221 tgggcaaaaa atgattttat tcttcttttt ttagcttcca gtatcaaata ttctgcaaat
    11281 tttttttgga tttcttccgt attttctttt gttactaatg tgtgttggat tagttttcct
    11341 gatggtcgct gatccaatcg ttcttctgac tgttgcacgt ccgcttgcgc aaatccgata
    11401 atccgttttt cttttgttac agcaacgagc aatagtttat tcttatcatt taggtcagct
    11461 gccgtttttg cttttacgaa tgattctgga tgatcagtaa tcagctgatt gatttgaggt
    11521 agatcttctt ttactgccca ccgtatttcc atcatttctc acttttcttt cgctcatttt
    11581 tatctccact aaaaaaatcg actgcggcaa ttgcatctat ccagctttgt gcaatgatct
    11641 catgtccgcc aatcgttggg tggaccccat cttctcttgt atatttcgaa aaaccataaa
    11701 caatccctaa agcattgaat ataccatcta aaggaaccag caatgcgcca tattccttag
    11761 caagtttacg aacaatttgg attttagggt ctaagtcttt acgccagcca tgacggtcgt
    11821 cggttatagg aagtacaaac ggctccatca agatgatgtt gcagattccc actgtttgaa
    11881 gttcatttag taattttcga taaacggatt caaattgctg agcagatttc tcagttccga
    11941 atatagcctg atcgctagta ttatgccagg tatcattgat tccgatcaaa atcgatacat
    12001 agtcaggttg taaagctaaa caatcttctt gccagcgtac ttgcagatct gcaattttgt
    12061 ctcctcctat cccacggttc atgcattcaa attccatcgt tggatattgg gagattagtt
    12121 ttccggcaat caaaagtgga taacctttac ctagatcagt tgcttctgct cggtctcttc
    12181 ctgcgtctgt aatgctatca ccgataaata atatacgttt tttcatttgt caaaaactcc
    12241 tttttgaata aaacgatgat tttcttcctt atattatccc ataagcccta tcaagacgaa
    12301 agagaaaata tatgtataaa aaatgacacc agcctagtcc cttcaaacaa ttgaatgaac
    12361 gctcatcaag tgtctagttt tttatgctat ttttttctta acgtgccgga ttccccttga
    12421 ttccttcgtt gtttggtcca gagagatcga tcacacctaa gcttccgtca atcagaccac
    12481 tgatgacgcc atcagaacat atatttatag gctcatctaa gacttctagt aaatgtccct
    12541 ttactaatat ctcttctaga ttgcttggga tagattggtc ataactttat ctggtccgat
    12601 gatttcaagg gtgaattgaa cttacatatg gattattgca tgctgaaaat acggacctac
    12661 tccatcttcg aatgttacta ttagtttgtt ttcaggtgct agatgctgct ttatttcaac
    12721 agcagaagca tcatcaaatc agatttccat ttgaattacc ttctttgtaa atgtttgatt
    12781 gattgcgatt tcgttataga accttgtgaa tcaaatagca atttcttttg ctttcttctc
    12841 ttgtctgctg gaaacttcct ttatcccgta ttttaaaaaa agaactgcga gagttcgcag
    12901 ttctttttta gaataaacgg tgctctccgg ccaactcctc ggtcacaagt cacaatagtc
    12961 atcaaacatg aaaaactgtt ttttgaaatt actccttgtg actcggagct gaacggcagg
    13021 cgcacaacct cttccttaaa cggtgttcaa aagccagttt ctcggtatta agccaaattt
    13081 atgcaaaaat gtggaaagcc atttccacaa aatttttctt aatactcgaa actaaacagc
    13141 tttttcacaa cctctccact aaacggtatt caaaagctta catctgcggt aataagtccc
    13201 gccaattcaa aaacatgaac agctgttttt gcttggctgt tctaattact tgatgcagaa
    13261 cagctttttc atcacctctt atggataaat tcggttcaac aaacgtggga atggaatagc
    13321 ttcacgtaca tggtcgatac cagcaatcca agtgactgtt cgttcaagac ctagaccaaa
    13381 accagagtgc ggaacagaac cgtatttacg tagatcaaga taccatgaat attctttttc
    13441 atccaaaccg tgattacgga tttgttctag caagaaatca tagtctgttg cccgttcgct
    13501 tccgccaata atttcaccgt aaccttctgg tgcgatcata tctgcacaga tcaccacgtc
    13561 ttctcttgtt ggatgtggtt tcatgtagaa tggcttgatg gcttttggat agtttaggat
    13621 aaagacaggc tgttcgaatg aattcgcaat gaacgtttca tgaggtgaac caaagtcttc
    13681 gccccattcg atgtcatcaa atccattttt cttcagtaat tcgatcgcat catcataagt
    13741 aatacgaggg aatggcaatt ttgtataagt ttttaagact tctttgtctc gtcctagtac
    13801 atctaatgca tattcgcaat gatctaaaac attttgtact aagaatgcta catattgttc
    13861 ctgtacttct aaactttctt cttgatgagt gaaagccatt tctggttcga tcatccagaa
    13921 ttcgatcaaa tgacgtcgtg tttttgattt ttcagcacgg aaagtcggac cgaatgaaaa
    13981 gacttttccg aaagccatag cagcagcttc catgtataat tggccacttt gagataaata
    14041 agctttttga tcaaagtaat ttgtttcgaa tagatccgta gtgccttctg gtgcagaacc
    14101 agtcaagatc ggcggatcaa ttttgacaaa atgatgttga ttaaagaatt catacgttgc
    14161 acgaatgatt tcatttctga tctgcataat cgcatgttgt cttgaagaac gcagccataa
    14221 atgacgatga tccatcaaga agtctgttcc gtgttctttt ggtgtgatcg gataatcgtg
    14281 gctctcgctt accacttcca catttgtaat tccgatttca taaccaaatt ttgaacgact
    14341 gtcttcacgg atttctccag ttactaacac ggatgtttct tggtgtagat ttttagctgt
    14401 ttggaaaact tcttccgaca cttcgctttt tacaactaca ccttggaaaa aggctgttcc
    14461 gtctcttaat tgtaaaaatg cgatttttcc gcttgatcgc ttatttgcga cccaagcgcc
    14521 gattgttact gtttctccca catggttttt cgaatcgatg atttgaattt gttccacgta
    14581 tgactctcct tttatattcc ttgaatttct ttaggattaa ttttgacttt tactctcaat
    14641 aaattgcttg attctgcgta ccgcttcttc taacgtagcg cgatcagtag cataactcat
    14701 gcggacattt tctggtgccc caaagccttc gccagtcaca agcgctaccc ctgtttcttc
    14761 taaaagatct tctacccatt gtgtgacatt ttcatattta cacatgcgta gcgtttcttt
    14821 tacattagga aaaagataaa aagctccttg tggcttttca agagaaacac ccggcagttc
    14881 tgccacaagc gaatataacg tattcaggcg ttcttcaaag gcgttccgca tttcttccac
    14941 tgtatcttgc tcgcctttca atgcttcaac agctgcatat tgactgactg ctgtcggatt
    15001 actggttgac tgggaagcaa cagcgatcat tccattgatg atcacaggat ttcccaccgc
    15061 ataaccaatg cgccagcctg tcatcgcata tgttttagac acgccgttga tgatgatagt
    15121 ctgatttttg attgcttctg aaatcgttgc aattggagta aactcattgc cattataaac
    15181 taaacgacca taaatatcat cagcaactat caaaatatca ttttttactg cccattcacc
    15241 gattgcctgc agttcattct tgctataaat cattccagtc ggattcgatg gagaattgat
    15301 gattacggct tttgtttttt ctgaacgtgc ttgttctagc tgttcaacag taactttcca
    15361 gctattggat tcttcccctt tcacaaagac aggaagtcct tctgccagtt ttacttgctc
    15421 accgtaactg acccagtaag gcacaggaat gatgacttca tcttgcgggt caaggatcgt
    15481 ttggaaaagg gtatacaaag caaatttcgc tccgtctgtt acgactgttt gtgaaggttc
    15541 atagacaagt ccatagtttt tcttcagata atcaacgatt gcctgtcgaa gctctgggat
    15601 tcctgctgtt ggtgtataat agctagcttt cccattgcgg attgtttcga ttgctgcttc
    15661 ttggatgttt tctggtgtcg caaaatccgg ttctcccaca gtcaaactca gcacatctct
    15721 gccttttgct tttaatgcct tggcctttgc cgcagctgcc aaagtgacag acggttctaa
    15781 tcgttttgtt ctttttgata actccatccc attcattcct ttacctttta aattcccttg
    15841 attgtcttga cttcatctcc agattcaaag ccaatcaggt aataattcag tttcccattt
    15901 gtttcttttc ctactacttc ccacacaggc tgatcatcat acatccctaa agcagctttt
    15961 tcgatttgga tttcaggatg ggccgcagca attgtctgtt ttgcttcgtt ttcagtcagt
    16021 ccctttgttt gatccaatac ttttactttt tcaccagatt taggaatgat aacggcgatt
    16081 tcttttcctt tatcatttgt acctgtcagt gaaaagtatg tcttctttcg agtaaaccaa
    16141 taaaaatgat cggtttcctc aagatttgca tatttctttg cgatttctac tgcttctttc
    16201 ttcgcctgca ccgccggacg actggaacgc aagtaaaaaa tcgagctgat cacgatgacc
    16261 gctaataaaa atacgatcaa gccaagtaac acgcgattaa tcgttttttc ctttgtctgt
    16321 tttttcttca agggtcgtcg ctcctttatc ttcattcctt ttcattatag cagattttaa
    16381 ttatgaaaaa agacagctcc tctaacttcc ttcttcattt ttctttaaga attcatggat
    16441 atcctgatag atttcctcca tagctagctc tttgatcggt acttttttcg gtaatgcatg
    16501 gatgatccgt gcgccatatt ttgcagtgac tagtcttcga tccaaaataa gcaatacgcc
    16561 acgatctgtc tccgtcctta tcaagcgacc taatgcttgg cgtaacttca aagctgcttt
    16621 aggtacggat tcctggtaaa aaggattgat cccctctgat tctaaataag cgttcctagc
    16681 tttgaccatc gggcgaagcg gattatcgaa gggtaaacgt gtgactacaa cgatctgcaa
    16741 agcatctcca ggcaaatcta caccttccca aaagctgtca gcgccaaaca atacgctttt
    16801 ttctgacaaa atgaagcgtt tcaaaagctt ctcccggctt ccaccaaacc cttgagctag
    16861 tatttctcgt cctttttcta gcatagacag atgcattttc tgatagacct tctgcaaaac
    16921 atcatgagaa gtgaataaca caagtattgg ccgatcttct tgttcgatca gacctgtaag
    16981 tgctgtctct aaataatcga tatatgcttg attgctgact tgatggacgg caggtgcctc
    17041 ttttggcaca tagatccttg cctgtttctc ataatcataa ggagaggcaa tcactttaag
    17101 aggtgctgct tcaatgccaa gcctcttaga gagatagtgt cgattagggc cgatcttcag
    17161 cgttcctcca atataaagaa tacgatcata tcgaggatac caaacagtcg acggcaacat
    17221 agccgcttga aaatcatgga gatgaaaaat catctgctgc gctgtgttcc caggaacgaa
    17281 ccaatggatc aaatgatctc gccagtcttc cagccattga tccatcagca agtattgctt
    17341 gtctaattga tcaaataggc tatataaact tgctaaatcg atccgcatct ggtttgtcca
    17401 gctttcttgg ataatctcaa aagtcagacg catttgtgac tgtagctgct ggatctcctg
    17461 ataaaaaagc tgcaggtgat caatggctgt cccagattcc agtggcagct gatccaacat
    17521 ctcttttgtc atcatgactt cttctggata ctgtccgtta ggttgcttgc cgctcactaa
    17581 actcattaat ccttctgcca tacaaatctg tgcttcgcat agcgcagaaa gttcttctcg
    17641 ataaatcgat aaccagcgta aggcttcatg ttctttcggt aaatagcttt gtattcggtc
    17701 aaacagctga tttggttctt ctaattgctg gatttgttta tggaaatagt taatacttaa
    17761 tcgtttgtca tttacttttt cagcgatttc cggcaaatga tgtacttcat cgatcaacaa
    17821 aaatggacta gctggaagca atggttcttt tcgctgtgtt tcttgtacta aaaacgcatg
    17881 attgacaatc aaaaaattac tttgcctgat tttcttttgc aagaaacgaa caaagtcttg
    17941 ttcgtaaaat gactgatttc ttgctaaaaa tccaatacct ctgtgcgcga tatctgcaaa
    18001 gaatgaatgg ttcaaatttg ttaaatgtaa ttcatccaaa tcaccagtct tcgtttgcgt
    18061 cagccaaact aagaccgcca tttgatacaa agcatattgt ttttgttctg gcggttccac
    18121 aagtgtgcct ttaaaacgct gcaaatcaat atagtggcga tagcttttga taattacagg
    18181 ttgtatgggc tgatctagca attgattcag caatggaatg tctttttcta tgatctgctg
    18241 ctgcaaaact agcgaaacgg tactgatgac agcgggtttt tcaggtgtag ccaaataact
    18301 caatggcagc agataaccga ttgttttacc cattcctgta gctgcttcga tcatcaaatc
    18361 ttttgattca tcttttgtga aatggtcgta gaccgcattc atcagtctgt tctgttcttt
    18421 tcgatacatc agtgttttac caaacatttt ttcttttgct tgtttttttc ttggatatgt
    18481 ccgctcgcca taatggacgg atgtgaatag ttccacttct tttttctgca aagctagccc
    18541 atcgacgatt tctaatgagg gatcaagtgg ctctggtttt tctttcattt cttcaatcac
    18601 atgataaatg aaacgactcg tatccatacc tgtgtgtcta cttaatcgcg caatctgctc
    18661 taacgtgatg attggcaatt ttctcatccg ttcttcgatc agcaaaagaa gttgacctgt
    18721 cacttcggca tcactatctg cctgatgagg attctcatga ataaatccaa ggctttctga
    18781 caaatcagct aagcgaaagc ttggttccgt cggcaagaaa atttgtgcaa gttctactgt
    18841 atcgatgcct ggtatcttca aactaggaag tccgcatcgc atgagttcat ggttcaaaaa
    18901 attataatca aaataaatat tatgcgcgac aaatatggtg tctgccaaaa gattgtaaat
    18961 cgtttgggcg acatcttcga aataaggcgc tttttggacg cgttgattcg tgatccctgt
    19021 taaatgctgg atttgttttg aaatcttccg ccctggatga atatcgatcg aaaaacgtga
    19081 agtgatccga cctgattcaa tcatgacgca gccaaattgg atgatccgat cttcttttgg
    19141 attcgtccca gtcgtttcga tatcaacgac tgcataagtt cttggtttca aaatatcttc
    19201 ctcttctcct gcctctaatg ttcttttgaa attatactac aaagtgcaaa aaaatactct
    19261 catcgctttt taaagaaaat agacaaaaac gcccagacac gcaaatgtct gggcgtttat
    19321 tttttagtat aggttaatta agctttagta acgtttgttg cttgaggtcc gcgttggcct
    19381 tcttcaacat cgaaagttac tgcttggcct tcttctaaag ttttgaatcc gtcgccttgg
    19441 atagctgaga aatgaacgaa tacatcgttt ccgttttctg cagtgatgaa tccaaatcct
    19501 ttttctgagt taaaccattt tactgtacct gtttccataa taaaaatcct ccttgtgtat
    19561 caacacatat tttgcaatta cttgaatggt gtatatctgg aagatgttta tttgaaacaa
    19621 gctaccacag attaccgaac aaaaactact cctatagtat atcataccgt ttacaaaaaa
    19681 gctagagttt ttcgactttt tttattaaaa aaagttttct cagcgattac ataaagtgaa
    19741 gaaccgaact ttttttaaaa taaacgacat attgttcagt tggtgttttt ttgctctgat
    19801 gttcttcttt aaactaaaaa aattattctt tctgactact tatcggttct gtttcaacgg
    19861 tcgaggctgg ggaagattct ttagtaggtc tgatgttctc atggtatttc tgatagccta
    19921 tgacagtgac cagaagaaca aggcaaacca atacgatcaa cgagattagt ttttcttttt
    19981 tgctcatatc tatacctcat aaataacagg atgatgtcca tcatatttct gagtatgagt
    20041 aaaagcaaaa gctgcagctg tagaatgtaa gaaatgccag caactttctt aatcacaggt
    20101 cggacagtac caaaagtaac caaatcttgg ctgcaaagac cgttcttctg tttcaggaat
    20161 cgcagaatca agatttggtg tctgtacata aacatttttg tacagacgtg tgcctgtaat
    20221 aggagaccgc tgtgtttctt cagcaaaaac tggctgactt gttaaactta gggatagaaa
    20281 cagcaaacac cataacagtc tttttttcat aaagacttcc ttatcgataa gtttttccca
    20341 attaaaatca tatctcaaga acgcccgtta ttcacatttt gttcataaat gatgtttttt
    20401 gtatcataat cgtcaaaaag aggtcgtgac cacgtcacaa cctctttttt aaacggtgtt
    20461 ccagaagtag cttcttcgga aataagccga aatttcacaa aaatttgaga aataattttt
    20521 gtcaatctct tcttatttct tgaagctgac cacttctgtc acaacctctt ccttaaacgg
    20581 tgttcaaaag cttgcatctg cggtaataag cccaccaaac aaaaaatatg aagagctatt
    20641 tttgcttgct gttcttatta cttgatgcag aacagctttt tcacaacctc tcatacacgg
    20701 tgtttaatca gctgaccttc ggtattagct caaaaaacgg caaaatatgt gaaactattt
    20761 ttccgtttgt ttctctaata ctcaggtcaa aacactgatt tcacaacctc ttttaataac
    20821 gaaaaatcgc tgtcagactc ttttcatctg gcgcatcttt ttgatccaaa ataaacactt
    20881 ttccgccatt aatgatcaca tcatctgcta atgcattcaa cacttgacgc cgatcatatt
    20941 ctgtttcagg atcttcaccg aaaccatcag ctaagtttga cgtagcgata aataaatgtg
    21001 acacttttcc ttctttcgca gctggaacga tatcaactaa ctgatcgatg aatttcttat
    21061 ctaagagttt attgtattct tttgattctt gagctgcgag ttcacttgac agcttcttcg
    21121 ccccttcttc gatatctcta aaggatagct gcgcaggaga agcagaaatc gcaacgtctg
    21181 cacaataata gggattttta gcaatttttt tgaacatcgt ctgattttct ggtagagcaa
    21241 ataaataaat cggccattgt tctggatttt cgaaagaatc cttcaagtac gtatcaactg
    21301 cttggtaata gttgacccaa tcgatctcta cttcttcatc ttttggattt acgccatgga
    21361 aagttactcc atctcgggct ccgcctcctc cattagaaga gaagttcaaa ccgccacctg
    21421 tcagttcaga tcccaatgca gtaacgacat caaccggtgc cccttctggt agagatactt
    21481 cttttacttg tttgttgctg acttcataca atttcatgga gtcgcggttc aatcccaata
    21541 aataataaga atagttgaac tgcccatttt tgataatagc cagtaaataa ggaagatcac
    21601 ttacatagta ttgatcgtct accgggatac tcaaacgatg gatataggtt tggtcagcag
    21661 ttataatgac cgctacactc gtagttgcac tacgccaaaa cgaaggatct cctaacaaat
    21721 tttcaatttt ttcttggaac ggggaccagt catgttcgta atattttttc tcaaaacgtt
    21781 tctttgcttc tttcgcaaaa tttttgaatt tgatctgatc tttttccaca tcttgatggg
    21841 cgacatgcgt attcagcatg atcgtgacga atggtccttt agcgccttct gaagtcaatt
    21901 gtgacaataa ttctttatcc ttttttgcca taaacgtacc cctcctaaaa aaatcattcc
    21961 tttgtttcta tctaaagtct accacaacac tatttttcca tacaataaaa cgtatctaaa
    22021 aaaataaaac ggtttctacg gttttaaatt tagctatttt tttaagttat cttcataatt
    22081 tcctcaatta tttagcccca gtcttcaact attcttcatg aaatgctgat aaactaagaa
    22141 aagaataaaa gaggtggatc ttatgcattt gattatgatt ttcagtttat taagtattat
    22201 cagtttattt gctttcagcg cttcccgctt attagatgcg gaaacacagc ctattcctgt
    22261 aaaagtacgt aaaaacgacc gctaaccttc cataacgtgc gttcttatcc taaagttttt
    22321 tcagaaacat tgaaactctc tcccctctct gataaaattt taatttgtag cgaaacaaat
    22381 taattacaag gagatcggat atgtccataa aaaaaacacg tctagtccta ttattggcta
    22441 gtctcattct ttgccttgct tcttttctac cagctgttgc tgtgcaagct gaagatacgt
    22501 tcaaagtaaa tgcaaaagca gcttttgctg tagatgcgca aagcggtaag attctttatg
    22561 atcaagatgg agaaaaaacc atggggatcg cttcaatcac aaaaatcatc ggtctttaca
    22621 tcgttcttga tcaagtaaaa gaaggaaaac tatcatggga tgataaagtt tcgatttcag
    22681 attatgcaga aaatttgagt atcaccccag atttatcgaa tgttcctttg cataaagaaa
    22741 acacctacac tgtcaaagaa ttattcgact ctgcaatcat ccagtcagcc aatgcttcaa
    22801 tggtggcctt ggcagaaaaa atctctggca gcgaatctaa attcactgaa cgaatgaaag
    22861 aacaattgaa agattgggga atcaaagatg caacgatcgt taatgcatca ggactgaata
    22921 actcttatct tggcgaaaac cgaccagaag gtactggaga aaacgacgaa aatcaaatgt
    22981 ctgctcaaga tgtggccatc gttgcccgcc atttgatctt ggattttcca gaaatactgg
    23041 acgtatctag cactacgaca caaatgtttg gcgaaaacac gcaatcacca gtggaaatgg
    23101 tcaactggaa ctggatgctc ccaggattcg ttaattacaa ggaaggcgtg gacggattaa
    23161 aaactggtac gactgagctt gcaggtgctt gtttcgttgg tacgatcact aaaaacgatc
    23221 aacggatcat cactgtcgta ttgaatgcgg acggccatgc ggaaaacccg agtgcccgct
    23281 tcaatgaaac agaccgtttg atggactact gctatgacaa ttggtcagaa aaagagctcg
    23341 gaaaagctaa cgcaagtatt cctagcctaa aaaccattga tgtaaaagac ggaaaagaat
    23401 caacagttcc tgttgtgctt aaaagccctg taaaagtatg ggtacgaaac gatatggata
    23461 ctggcaaatt aacgatcacg ccaacacttg acaagaagca agtcactgac aacgagatcc
    23521 aagcacctat ggataaaggt acaaaaatcg gtaccgctac gatcaccttg gcagacgata
    23581 aattaggcta tttagaagac aacaatgcgc catcaacaga gatcattacg gataaaacag
    23641 tggaaaaagc gaatatgttc gtgattggct ggcgacgcgt cgcagaattt ttcggcaact
    23701 tgttttaatt gaacaataag aaaagcatct ttccatcgga aagatgtttt tttgctttta
    23761 ctagtttaaa taacagcttt tttcatctat tttcgttata ctgtataaga aaaaggagtt
    23821 gaatttatga atctaaccag agatctgatc tttttagttc tctatcttat tggggtattc
    23881 tctatcgttt attggcgaaa acagaagaag gatccttcct tgttctttta cggcagtacg
    23941 tggacattta cggtaatctt aacttatttt gtcgtgttgg aaatttttta ttcgaccttt
    24001 tattttttga ttccattgtt gttctttagt atctttgctt tttcttattt cacagaaaaa
    24061 cgaaggctgc tgaatggtct tttattcaat gttttcctca tcagtttcgg catctacttg
    24121 tttgtcttgc tgtatgaaac gcaaaatatt ttccttggcg gactgatcgc cttgatcacg
    24181 attccattgc tacttgtcct tttatttggt atttatggat tgattgtttt tcttttttgg
    24241 aacggggtca cagttttacg tagagaatcg cattcattag ctaatctttt aacgttgata
    24301 ctagccattt ttcttacact gtttcttgtt tttgactttt tcttgttaaa atatttgccg
    24361 caatggataa atgctttgtt tttctgcgtt cccctgatct tgatctatct atttatcgta
    24421 ttctacaact ttttgactgt ctcattcttg tatcagttca accggcctcg atacaatcaa
    24481 gacttcatcg ttgtgttagg cgctgggttg atcaatggag aaacagtttc tcctcttcta
    24541 gccaagcgaa tcaataaggc aattgctttt tatcgggctc aaagccgtgc tacattaaat
    24601 ccgcccatct tattgatgtc tggcgggcaa ggagcagacg aaaaagtacc agaggccatt
    24661 gcgatgaaac aatatgccat ggaacaagga attcccgaaa gagacattct tgtcgaaacc
    24721 aattcgacaa ccactttgga gaacatgctc tattcaaagg aaatcatgga tcagcaaatg
    24781 aaagggccat accgcgcgat cttcagttcc aacaattacc acatttttag agccggtctt
    24841 tatgcgcgac aagccaaatt gaaagcaaat ggtattggtg caaaaacagc tttctactac
    24901 ttgcctaatg cgttttgaga gaatacatcg ccatcttgat gatgaacaaa aaaagacata
    24961 tgatcatttg cggattgctt ttcgcaggct ccgcattctt atcgctgatt actttacttt
    25021 tctaaaaaaa caaggtgtga caaaacatat gtcacacctt gtttttttct ttcattctct
    25081 taactattgg caaaaagagt atcccttttt tgaccgctac ttgctgagca gaataaatac
    25141 cgctgttgcc tgaacacata aagctgatca agcagatcat aaagaagtat actgccgctt
    25201 gtgaaccgaa caattcgatc cccatcacaa agcaggcaat cggtgtattt gtcgcaccag
    25261 aaaatactcc gataaagccc aatcctgcaa gaaaaggaac agaaacatgg agcaaaggcg
    25321 ctagtgctgc accaagcgtt gcaccaattt caaacaatgg tgtcacttct cccccttgat
    25381 atcccgcgcc taaagacaaa actgtgaaga ataacttccc aataaaatca tagacatgtg
    25441 cctgtccatt aaatgattct tgaagtaacg gaagactcaa tccgagataa cgttgtgttt
    25501 gcaaaatcaa tgctgctgcc acaactacag ctccacctat cgtatttcgc caaacaggat
    25561 gaggaatcca ttgtgcatac cgtgctttta aaaagacgat cgaacggctg aatacccagc
    25621 caatcaaacc aaaagcaatc ccagcaacaa aaactttgaa gaacagcaac atactccatt
    25681 cagggatcac acccatttgg taatgtaggt gagaaacacc atagctttct gtcataaaat
    25741 ttgcaaacag tgcagcaaag aagctaggga agatcgcttc tgttcggact ttcccgattg
    25801 ccaacacttc taatccaaat aatgttccag ctaaaggtgt gccaaataca gaactaaaac
    25861 ccgcactgat tccactgata atcaagattt cccgttctgc tttatccaat cggaacaaac
    25921 gtgctgtatt atctgctaac gctcccccca tttggactgc tgttccttca cggccaacag
    25981 atcccccaaa taaatgggta gttatggttc caaacagtgt aagtggaata agtcgcaacg
    26041 ggattttttc ttctccacca tttccttgat cgatcactaa gttgtttcca cgactagaaa
    26101 gaccgccgtg atacgcatag agataagcaa aaagcgcacc actaactggt agtagataaa
    26161 ggagccaagg atgtgatagt cggatatctg tcacaactgt caggctattt aagaaaaaag
    26221 cagacaagct ccccatgaat ataccgagaa tcgctgtgat caccagccac ttcagcatgt
    26281 acactaaaat gcgtactgta ctcggtaatt gtttttccat aaaaaattcc tcctcaataa
    26341 aaaaacgcct actaaagaaa ggggctgtcc ccagacttta gtaggcgtca ttagctatct
    26401 ttcgttagca tttaaaggcg aacaccatca cctattcact tccattaaaa gatagcatat
    26461 ttttctgtaa aaaacaataa aattatcgtt ctttctttac acgttcagca aattcataga
    26521 aaggagccaa tttcgttaac tgttgattac attggtcact atcatgacaa atataatttc
    26581 cctttttcgt atacgtgcca tcagaacctg ctttcgttgt agaaagaaaa agcgaaacat
    26641 tcgatgtttt ctgacagatt gcacagattc ccttatttat cgttggtgat aaagtaccgc
    26701 taatcccttt taatttttca tcttcgtaat agaccatgaa ttttttctgc gtacctggat
    26761 cattccagcc gatgtaagta tgttcttgca agtcgatttc attccaagct ggttgtttga
    26821 gttttttcac ttttcggaat aatttctcga tttgtggttt gctaggctgc ataaacggct
    26881 gaacgatttg cttcagctcc tccaatgctc tttctgcttg cgcttttgtc agttttacgt
    26941 ctaaaactgt cgttaaaaat gtatcgattt ctggcagttc gtgatctaat atgtctcgaa
    27001 tcttttcagc tgctagtgcc tgaactgttt gtaccgtttt tggatcattg acagatgagt
    27061 acgcatttaa taactgttct acttctcttt ttataaaaaa atattggtat ggttttattg
    27121 tttgttccat gattttaaag tcctttcttc taaccaaagt gcatactttg tagaaaaaag
    27181 tgatcttctg caaagtatgt gttacctgaa gatcccggac tcttttaaat aagatacgtt
    27241 ttgcatctta tcatcacccc ctttaatgct tattattcta tgtacatgat tcattcgata
    27301 aataaaagta aaccgtatct tgaacagata gtcaactgca aacagaaaaa aggactgtga
    27361 caaaagtcgt gtcaaagtcc cttgtttcga atgaatggtg ttcaaaagct tgcatctgcg
    27421 gtaataagcc gaaacttcac aaaaatttga gaagtaattt tcgtaaattc cttcttattt
    27481 cttgaagctg accacttctg tcacaacctc aatatggtct attattggtt ttacctgtta
    27541 aatcgaggat tctttcccaa agtaacgttg ccatctctta cgcatacttg cagacatggg
    27601 ctgagccgct tctttgactg cgcagtattt gtccacgaat gtcacaatat atccttcttt
    27661 atacttaggc ggtgcgatcg ttgcacccca catgtgcttc aaaatgatat ctcgctcaag
    27721 atccgacaaa tcggtgattt tttctgcatt ctttacagca attcttggat ggatatacgc
    27781 atgtgtcccc tcgtcaaatt tcgtcgtacg ccaatcatag tagaacagat catgcaaaag
    27841 tccagcacgc gctgttgctt tagcattgcc accccatttt tttgcgagca gataactata
    27901 gtaagaaaca ctgatggaat gctccaaacg agtggaatga acatgctgtg tgtaatttgc
    27961 taattttttc actgcttctg tttctaaaag atcttgtaca taagacatat attcttcgtc
    28021 ttcacgccat ttttctgtca taattatcga tctgccacct ttttgaattt cattttcttc
    28081 tgaaattgat ctaagtatac caccagtgtt cggattattc tagtcgctct agataaaata
    28141 gctaaagctt aatagttcct taatcataaa gaaaaatgat aaagaacgat ccctgctgcg
    28201 actccgacat tcaatgattc cgcatttcct ttcattggga tatatacgtt ctgatcagtc
    28261 aaagacaaga tttcctgact tactccctga ccttcgtttc ccatgattat agcgaaatcc
    28321 tctgtttttt ctactttgtc taatgcatgt gcttcttcat ttaattctgt accgtacacc
    28381 gtaaaccctt tgcctttcat tacagggatc acttctgcca aatctttttg taacacaggc
    28441 aaatgataat tgcttccctg catgcttcgc agcacctttg tactataaat atctgccgtt
    28501 cctttaccta ataaaacacc agccatacca aacgcatctg ccgtacggat catcgttccc
    28561 acatttccag gatcctgtac attatctagt aaaagccagc ctcctgaaaa atctggcgta
    28621 tctttagatg ttaacgtcat cactgctaag atcccttgcg gtgtaggtag atctgacata
    28681 gcggtcatga cctcatctga aactagaaaa gtagaaatct ctttgtttac agccagccag
    28741 tctccccatt ctttcatacc tctctgtgtc acaaaaagtt cttttatttc tacatcagac
    28801 gacgcagctt cttcgatcag atggaaccct tccaaaagat attctgcctt ttcttctctg
    28861 tatttctttt tatgtagttt ttttaattct ttgattcttg gattttttgc tgattggatc
    28921 tctttcacat tccttcacct cacctgatta tatcatggaa taggtgcttg agcttgtttc
    28981 atcctaaaaa aatcggtatc attgatttat aaaacaggaa agaaaggtga cgaacatgcg
    29041 caaagttaaa atgaatgtcc aaggacgtgt ccagggcgtg ggatttcgct atatgaccaa
    29101 gatggttgct gatcagttag gcgtgaccgg aacggtaaaa aacgaagacg acggctcagt
    29161 cacaatcgaa gcaatcggaa atgacgacat catccaaaaa tttatcgaag aagtcaagaa
    29221 gtctccgagc ccaagtggac gagtgcagta tgtggatgtc caagaggatc cgatgattga
    29281 ggaacgaaag aaatttgatg tggtgggata aggttgtgaa aaggtcgctg agttttgagt
    29341 attaaggaaa attttgtgaa aatagctttc cacatttttg cataaatttg acttaatacc
    29401 gagaaactga cttttgaaca ccgtcgatca ggttgcgaaa aagctgatct gcatcaagca
    29461 ttaaggactg gttgtgaaaa agtcgcttag ttttgagtat taagaaaaat tttgtgaaaa
    29521 tggctttcca catttttgca taaatttgac ttaataccaa gaaattgact tttgagcacc
    29581 gtcgatcagg ttgtttttga ggcgctttgc ctcaagtatt aaagataggt agtaaaaaag
    29641 ctgatctata acttgcaata aatttgctta acccatattt tccagacaga acaaaaaagt
    29701 ttttagtttt ttaaataaga aagaaacact tggaatcact cttttctttc caagtatttc
    29761 tttcttgatt ttttgtcttt tttcaaaatt tttcgctacg aaaaagaaag aatatttata
    29821 tgaaatttct atgaagttga ttgaattcca tgcgcttttt tagtatagtt aagtttgtgt
    29881 aaaaattata gaagaggaag tattctatga ataaatggaa aaactggtta ttgggatccg
    29941 gacttgtcag tatcctgctc tttttatctg gctgtgtgcg gatggattca aacggaaacc
    30001 ctgacacttc aggaatcgtt tatcgagtac tcgtccatcc tatgggccaa gcgattacat
    30061 atctagttga gaatttcaat tggtcttacg gctgggcagt tattgcaatg actgtgatcg
    30121 ttcgtatcat catcttgcca ctaggtatca gtcaatcgaa aaaaacaatg atccaatctg
    30181 aaaaaatgca agcgttaaaa ccacaagttg aagcagcaca gcaaaagcta aaagctgcaa
    30241 caacacgtga agaacaaatg gcagcacaag cagaaatgca gcaagtatat cgcgaaaacg
    30301 gattgagtat gaccggcgga atcggctgtc tgcctctatt gatccaaatg ccgatcttct
    30361 ctgccttgta ttttacggct cgctacacag aaggtatccg tgaatcatct ttttacggca
    30421 tcgatctagg ctcaccaagt atggtgcttg tggccatcgc aggggtcgct tatctgcttc
    30481 aaggatatat ttcaacaatc ggtattcctg aagaacagaa aaagacgatg cgtacgatgc
    30541 tgatcgtctc tcctgctatg atcgtcttca tgtcgatcag tgcgccagcc ggtgttacac
    30601 tttactgggt agtcggtggt gtgttcagct gtctgcaaac attcatcaca aacgttatga
    30661 tgaaaccacg tttgaaagca caagtggcag aagagttgaa acaaaacccg ccaaaacaag
    30721 tcgtcactcc aagaaaagac gtgacagaat cagcaaagcc agctgacaac aaacaagcaa
    30781 caaaacaaat caaacaacca aaaaacagta caaataacaa aggccgcaac gcaggaaagc
    30841 agcagaagcg gaagtagata gtaaataaga gtgtaataaa aattcattaa cagttttagt
    30901 aattaaaaat atcgaccaag atttttgaaa aagaaatctg gtcgatattt ttatttaagt
    30961 gaatgtttaa tttgaatcat cgattgatcg ctatctaatt gcagcagcat ctttttatga
    31021 agaaacaact ttttcttatc tatcaacgta gacaggtgtt gctgtttctt ctaatagtgt
    31081 acttaattct ttaatatttt gttttccttc ttctaacatc caactactcg ctttttcttc
    31141 gccttcggta acaaaaggtg ctactccctt cgcccatgtt gctcgtccac ataagacacc
    31201 attgaatgtc gaacctgatt gttttgcaaa acgcaatgta tcttgaaata gtgcagcgct
    31261 gactcccgca ctaaaaaaaa taaacggttg ttcagttact ttcgattgtt catagaaata
    31321 agtggatgcc tctgcttgac tataacaagt ctcttgccca tatcctttca caaatctcat
    31381 attcactggt acttctactt tcaatacatc cacttgataa cgttcttttg aaaattctcg
    31441 catggcttca atcactttat gcggttttac ttttgcatag gcaagagaag acggatcgct
    31501 aatagttgca tcataagaaa ggatctctaa aaagaaaggc ataccttctg cttcgcattc
    31561 tgaatcaatc cgttctataa ctatttgttt ttgcacatta atctctactg attcatcaac
    31621 gtcatagtac aataaaaatt tacaagcatc cgcacccact tcttttaacc ttttcactga
    31681 ccaactattc agtaaatctg gtagtcggcc cggcattttc gcatcatagc cggttttttc
    31741 ataagctagc aacaagccac attctttctc tcgaagcgct gctgcaggca gaccatattc
    31801 tggatcgagt aaaatagcgg aagcatacgg agtcaggtac tgagaaacca tctgtttaaa
    31861 ttggatgata tcttctgatg tagcttcttt atattggttg atcatttttt tcaaagcacc
    31921 acgctggtcg attgctaacg cgctaataat tccagcttca tccgtcaatc gcttcaaaca
    31981 ttcctgtttt tctatactca ttttcttcat atatcttcac ctatttcttt agttaatatt
    32041 gtggctattt ctgtttttga ttttgctgct ctcaactgtt ctgtaacctc ttttcgcatc
    32101 aatgatcgtg caacgagaga caataatttc aaatgagtcg ttcctgcttc tgaatctggg
    32161 ataaataacg caaaaataaa atcaactgac tgtctatcta aactgttcca ctcaatccct
    32221 ttgttcagtg tgacgataat caaactaggt tcgttgattg tttgagactt cgcatgaggg
    32281 atagcaaaac ctgacattat tcctgtagta ccttcttttt ctctttctag aagttttcga
    32341 tatacttctt tttcgtcatg agcgattcct aaacagaatg tttgctttgc taaaaactta
    32401 aatgcttctt cttgactatc taatggctgt tgtaaaaaaa tgttctcttc atgaatgatt
    32461 gtcatgataa gcctcctgct cttccttctt cgataactgt acgatttgct gctttattat
    32521 ccatcttctt gtctttatca gttactcttt tcttttggat caaacctagt atcactccac
    32581 caacgatcga accaataaga atcgctgtaa cccattggat ttttcccgtc actacaggta
    32641 acactaaaaa accgccatgt ggggctggta cttggacacc aaacagatag gtcaagacag
    32701 cagcaattga tgagcctaac atcatcgttg gtaatactcg gatcgggtct ttcgcagcaa
    32761 acggaatagc tccctccgta atatgagttg atcctaaaat aaaattaacc aaacctgcat
    32821 tacgatcatt agtatcaaaa tatttaccaa acaataaagt tgcaaaacca gtaatcaacg
    32881 gtggtgcaat gcaagctact gacacgccag ccataaaagt cgtgtttcct tgtgccaaaa
    32941 gagctgtacc tgttacatat gccgccttat taatcggtcc tcccatatca aacgcacaca
    33001 tgcaaccaac aatcacgcca agaacaagtg gattcgaatg ttcaaatcca gctaaaaagc
    33061 tcatcattcc ttcatttata gccttcattg gacccgccag caaagacatc acgatgccga
    33121 taaacactac accaataact ggatataaga agattgcctt caagccatct agttgtttag
    33181 gtaaaattgt cagtagcttt tgcaaaaata agataaaata acctgctaag aacccagcta
    33241 aaatacctcc taaaaatcca gtaccgccac tcatggccac gattccacca acaaatccaa
    33301 cgactaaccc tggacgtttc gcgatccctt ctgcaatata agctgctaaa actggaacca
    33361 tcatccccat tgctgcatcg ccaaccgttt ttaacatcgc cgctgtagca ttgtattgtg
    33421 catggtctgg atcaaaagaa tagattcccc aaacggcaaa tgaaatagca atcaatactc
    33481 cgccagctac cacgaaaggc aacatatgag agacgccatt cattaaattt ttatagatgc
    33541 tgcgaccaaa attagcacca cttatcgttt ctgattctaa agtatcaaca gcttcattat
    33601 ctgctaagat ggtccctttt cctgccaatg cttcgtcaat cagccgttgt gcatccttga
    33661 ttcctgtact gacagaaaca tcaatgactc gttttcccgc aaatctttct gaatggacat
    33721 ctttgtctgc ggcaataatg acagcatctg cctgtttgat ttcttcagcc gttaattcat
    33781 tctcgatccc aatttgtcca tgggtctcca ctttgatcgt gatgcctttt tttctagctg
    33841 cttgctctaa tccctcttgc gccatgtagg tgtgtgcaat tcctgtcgga caaccggttg
    33901 ctgcaattag ttgatatttt cccatctttc gaacctctct tccttgattt tgatttgttt
    33961 acttaattcc tccacatcca aaaaatcagt cagtccttta cgaaaagcag tagagctgcc
    34021 tgctgctatg cttttacgta acgtttcatc aagcggtcgt cgattcatgt atcctactaa
    34081 aaaagtgcct aacatggcat cacctgcaca tgctgtattg acaacttttc cttttggcga
    34141 gtttcctcga atcaccctgt ctttcgtaaa aagaatcgct cctttctcac caagggataa
    34201 caaaacattt tctgcacctg actctaccag tcgttgtcca taaacaaagt aatcttcatc
    34261 tgtaaccatt tttcgtccga accaagaaga aagttcttcc tcattcggtt tcagcaaaaa
    34321 tggtcgatag ggcaaacaac ccatgacctc ttgatcactg ctatcaataa tcaaatgaat
    34381 ctccttttcc tgacaaatcc gactgatttc cactaaaacc ttcggagaca ttcctcttgg
    34441 taaactccca gaaacacaaa gataatcctc tgcttgtaat gctcttattt gatttaaaaa
    34501 attatggaca gctgcctgcg gtatttcagg tccttgattc actaatttgt attcttctct
    34561 cgtttgattg acttgtgtaa atacattgat acgcgtcata ccaggcactt caataaactc
    34621 tgtttggatt tgtttcttct gtaaatagtc ttctatatat tttcctgtga aaccagcaga
    34681 aaaacctaat gccgtacttg ggaaatctag catctttaat actagtgaca catttacccc
    34741 ttttccgttt gcctgaatgt catcctcctt tgtacggttt accataaaag gatgcatctc
    34801 ctctgtttca ataaatagat caattgccaa attcatcgtg catgtgtaga tagacataac
    34861 caatgacctc cttgaatcta ttatgaaata cgcgaaagag aaaatgtttt cttaatcgtt
    34921 ccaacacaaa gaaaaccttt acatttataa acacatcgtg ctatttttta actaactttt
    34981 agtgaaagaa ggaaagaata tggatcacaa attaagtgaa acagaacagt acctctggaa
    35041 ctttatcgaa caccacatcc tagagatccc taactactct atcgtgaaac taagtgaaca
    35101 agcaaatgtc tcaacagcca ccattgtgcg gacaatgaag aaaaaaggct atgaaggatt
    35161 tacttcgttt aagcaccatc taaaagaagg agaaaacaag aacatcaatt tttctttctt
    35221 agataaagta gacaaaggta tccgtcgagc cattctaaaa aatgaacaag aagtggtacg
    35281 tacgatcaat atgttggaaa tcgggaacat tgaagatgca atacaaagaa tcaaatttac
    35341 tgaccgggtt tttgtctttg cccgaggatt ttcagaaatg attggtcaag agatgctcgt
    35401 aaaacttcaa ttaacaggaa aaaattgtca aatgcatact gatccagaga ttatcaaaag
    35461 catcagtcgg aaactaacta agaaagacag cgttattttt gtttctttga acggcgagac
    35521 aaaagaactc gtcaccgccg caaagaactg ctatgatgca gagattggtt cgattctagt
    35581 tacagccaat cattcctcta cactcaaaga ttattgcgag ataaatctcg taggtttcaa
    35641 atcagaaggt tcttatttcc ctgattatga agtacgttca cgcttgcctc tccagatcat
    35701 cgcgagaatc ctgcttgacg cctatgtatt gcgtatgagg gagaattgag aagcagttta
    35761 ttatggttgg ttacagttta aaacatcaca ttttttattc tttatattgt atggactcac
    35821 gtaaactttt tatgtataaa gttattca
//
LOCUS       DACDLM010000025        35384 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.025, whole genome shotgun sequence.
ACCESSION   DACDLM010000025 DACDLM010000000
VERSION     DACDLM010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35384
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.025"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(97..1116)
                     /locus_tag="IV356_001258"
     CDS             complement(97..1116)
                     /locus_tag="IV356_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP9014957.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(1138..2145)
                     /locus_tag="IV356_001259"
     CDS             complement(1138..2145)
                     /locus_tag="IV356_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAP9014958.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            complement(2138..2803)
                     /gene="pgmB"
                     /locus_tag="IV356_001260"
     CDS             complement(2138..2803)
                     /gene="pgmB"
                     /locus_tag="IV356_001260"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAP9014959.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            complement(2796..5090)
                     /locus_tag="IV356_001261"
     CDS             complement(2796..5090)
                     /locus_tag="IV356_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAP9014960.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            5350..7515
                     /locus_tag="IV356_001262"
     CDS             5350..7515
                     /locus_tag="IV356_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP9014961.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            7819..8652
                     /locus_tag="IV356_001263"
     CDS             7819..8652
                     /locus_tag="IV356_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HAP9014962.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(8754..10454)
                     /locus_tag="IV356_001264"
     CDS             complement(8754..10454)
                     /locus_tag="IV356_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014963.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            10961..12121
                     /locus_tag="IV356_001265"
     CDS             10961..12121
                     /locus_tag="IV356_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP9014964.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            12137..12580
                     /locus_tag="IV356_001266"
     CDS             12137..12580
                     /locus_tag="IV356_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP9014965.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(13063..13593)
                     /locus_tag="IV356_001267"
     CDS             complement(13063..13593)
                     /locus_tag="IV356_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HAP9014966.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            13698..14249
                     /locus_tag="IV356_001268"
     CDS             13698..14249
                     /locus_tag="IV356_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP9014967.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(14402..14875)
                     /locus_tag="IV356_001269"
     CDS             complement(14402..14875)
                     /locus_tag="IV356_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP9014968.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            15013..16485
                     /locus_tag="IV356_001270"
     CDS             15013..16485
                     /locus_tag="IV356_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAP9014969.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            16482..17192
                     /locus_tag="IV356_001271"
     CDS             16482..17192
                     /locus_tag="IV356_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HAP9014970.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            17544..17828
                     /locus_tag="IV356_001272"
     CDS             17544..17828
                     /locus_tag="IV356_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HAP9014971.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(18109..18528)
                     /locus_tag="IV356_001273"
     CDS             complement(18109..18528)
                     /locus_tag="IV356_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HAP9014972.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(18530..19114)
                     /locus_tag="IV356_001274"
     CDS             complement(18530..19114)
                     /locus_tag="IV356_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HAP9014973.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(19161..20636)
                     /locus_tag="IV356_001275"
     CDS             complement(19161..20636)
                     /locus_tag="IV356_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HAP9014974.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            20817..21128
                     /locus_tag="IV356_001276"
     CDS             20817..21128
                     /locus_tag="IV356_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014975.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(21243..23579)
                     /locus_tag="IV356_001277"
     CDS             complement(21243..23579)
                     /locus_tag="IV356_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP9014976.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            23721..24389
                     /locus_tag="IV356_001278"
     CDS             23721..24389
                     /locus_tag="IV356_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP9014977.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            24392..25435
                     /locus_tag="IV356_001279"
     CDS             24392..25435
                     /locus_tag="IV356_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP9014978.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(25672..26553)
                     /locus_tag="IV356_001280"
     CDS             complement(25672..26553)
                     /locus_tag="IV356_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP9014979.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            26712..27440
                     /locus_tag="IV356_001281"
     CDS             26712..27440
                     /locus_tag="IV356_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HAP9014980.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            27596..27913
                     /locus_tag="IV356_001282"
     CDS             27596..27913
                     /locus_tag="IV356_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP9014981.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            27906..28514
                     /locus_tag="IV356_001283"
     CDS             27906..28514
                     /locus_tag="IV356_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HAP9014982.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            28530..29360
                     /locus_tag="IV356_001284"
     CDS             28530..29360
                     /locus_tag="IV356_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HAP9014983.1"
                     /translation="MRLKHFLITGIGLMLTGGLLAGATYTLGAQKSLTWDNGPRLIDM
                     VTETKKIKDANKIVIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKK
                     STGAIISLEDTSAQITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSF
                     NEFTGGTITAKDELGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSL
                     HEMENSGYTIQTSGESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD
                     "
     gene            29498..30010
                     /locus_tag="IV356_001285"
     CDS             29498..30010
                     /locus_tag="IV356_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HAP9014984.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KIKKVTLDIY"
     gene            30036..30908
                     /locus_tag="IV356_001286"
     CDS             30036..30908
                     /locus_tag="IV356_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HAP9014985.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            31084..31446
                     /locus_tag="IV356_001287"
     CDS             31084..31446
                     /locus_tag="IV356_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAP9014986.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            31455..32207
                     /locus_tag="IV356_001288"
     CDS             31455..32207
                     /locus_tag="IV356_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9014987.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVKPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            32221..34023
                     /locus_tag="IV356_001289"
     CDS             32221..34023
                     /locus_tag="IV356_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9014988.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAEKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            34300..35340
                     /locus_tag="IV356_001290"
     CDS             34300..35340
                     /locus_tag="IV356_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAP9014989.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
BASE COUNT        11053 a         6255 c         7288 g        10788 t
ORIGIN      
        1 tttttacaga taaacaatgt gttagaagta gtatcttctt ttacataaaa agctgaccat
       61 aggataaatg gtcagcgtat ttagtgagtc agctatttag tatgggtttt ctaaaggaac
      121 gactgtctct cttttgatca agcgatgagg gatgaccaaa cgtacgccac tgctcaattc
      181 ttcatggatc aattcgcgca gcttttgcat agcgacacgt cctaattcgg agatatcgat
      241 atcgatactt gtaaggtaag ggtgtgttaa tgttgagaag atcgagttgt tgaagctaat
      301 gacggagagt gtctctggaa tgacatagcc atacatttgc gccaactgca tcgtgcgaag
      361 ggcgaagata tcgtcaatga ccaccaatgc tgtggcttcg ttttctttca acgttttctc
      421 aaaggacaga taatcctccg gatgctctag tactacactg gataacgcag gaagaccagc
      481 catcatcatt gctttttgat aaccgaaata tcgttcgaaa tacaaacttt catgagtcgt
      541 gtttgtcaca aacaggatat tcttatgtcc attctggatc aaaaattctg ttgcttgttt
      601 acctagaagc tggttatcat tatctacata aacgatttcg ttctcatgat gataaggctg
      661 tccgatcaaa gtgaaaggga tgtggttttg gtataaataa tcaatgacag tatcttgact
      721 atctgaatac actagaataa aaccatctac ttgtttttgt aaatgcatac gctggacgtt
      781 ctctaacagc aattcaaaat ttttagcagt agcgattgct gtagtcatat cataattccg
      841 cgcttcttcg ttgattgctt ccatgatctc aagataaaat gggttaccga tccgctcttt
      901 tgaatcaaga gggggtaaga ttacgccgat ggcactggaa atgcgttttc ctagattgcg
      961 ggcagtcatg ttaggaacat aacctagttc atccataatt tttcggactt tcttctttgt
     1021 tgtctcggaa atactaggat gatcgttgat gacacgagag acggtcgagg tggcaacacc
     1081 ggcttttttc gccacatctt ttacggtaat agccatgata aaaacacctt tctcttgtta
     1141 ttgtgcagag aaccgataaa tcgtctgact gatccgttct tgaccaggat ggaggttgat
     1201 cgatccaaat ttggggaaat gaacgatatc agggatttct tgcggttcga ttgctaatcc
     1261 gtagtttgaa tgcatctgtt ttccattgac agagaaatca gcttcgaatc cagtcgtaga
     1321 aaataatacc atacttttat tagaagttgc tatagtcatt tggcgaccag aatgcttctc
     1381 gaataattgt aaggaagttt tggaaagcct aggatgatgc aaaagaaata catcatctag
     1441 tccatctgga taacatgcaa ggatctcttg cagtgttggg gattttctaa agtcgattgg
     1501 cagtttttct ttttttgtcc aatttccagt aggcagtttt tcttgatcta attcaagcac
     1561 accatctaaa aagaccgtta actgatgttc atagatgtct cttgttccat ttcctgaaag
     1621 gttgaagtag gcatggttgg tcggattgca gatggtttca acaaggctac tagcagaggt
     1681 tgtcatctct aattcgtttt ttgttaaacg gtaagtgatc gtagcagtga ttggtcctgg
     1741 ataggtagaa aattcatctt ttaagtaaaa gaccacacct attgatgatg gagttttgaa
     1801 aacttctact tcccaaaatt ggaaagacca gcctttcgtg ccaccgtgga tatggtgtga
     1861 tccgcagttt ttctccaatc tatgctcacc ccaagaagca tcccggatcc ttccggctac
     1921 aggtccgaca gttgctccaa aaaagctttt gtctgttaga acatcttcga aacgatcgta
     1981 agacaataaa acattttctg attttccttc tttgtctggt gcgaagattt ggtgcaggcg
     2041 ggcaccgtaa ttgagaagaa cgacttctaa gtagtcgttc ttcaatgtga ttttctttat
     2101 ttcagtctct ggaactggta cgacggagat ctctggatta tccatggtca tgccactttt
     2161 ctttcaagta atcgatcgta agaaaagtcg tatcagggac aagcgggatc tcctctccaa
     2221 ggtcttcagc acgtcccacg ccaattggtt gagcgccact tgagaggatg gcttggatac
     2281 cggcttgcgc gtcttcgatc ccgatacatt cttctgcttt tagtccgaca gcttttgctg
     2341 caaggaggaa gatatctggc gcaggttttc cgtttgttgc ttctgccggg tcggcaatag
     2401 catcaaagta aggtgtaaga cccatttttt caagtaggaa tggcccgttt ttacttgcag
     2461 aagcaagagc aatcttgatt ttttcttctt ttaaagaatc cagtaaaggc acgaccccgg
     2521 ggaagacatc ttttggttcg atcgtctgga tcatctctaa ataataatcg ttttttcttt
     2581 tcgctaattc tgcaaattct tcctttgaaa aagagtgttc ttttccgcca taagctaaaa
     2641 gcaaagagag tgagtcttct cggctgacgc cttttagctg ttcgttgaat gtgtggtcga
     2701 tcgtaatgcc gatttcctga ccaagctttc gccaagcacg ataatggaat tcagcagtat
     2761 cggtaatgac accgtctaaa tcaaacaata cccctttaaa catttgcttc ctcctttctt
     2821 agcgttattt ctagacgatc cgctaaagaa taagactgtt catagacgta aatttctaga
     2881 ggagaacctt ctaataactc gaaagtaact tgttcatctg tgactgagat gaacaataaa
     2941 cgtccgcgat aattgatatg gaaagaataa gctttccaag tttttggcag aaatggtgcg
     3001 aatctcaact gatcatgggc agttttcatt tgagcaaatc cttggacaat cgacaaccag
     3061 ctaccagtca tggaagtgat gtgcaagccg tcttctgtgt cgttattgta attatccaaa
     3121 tccaagcgag ctgttcgctg gtacatttct acagctttgc tttccattcc taattctgct
     3181 gctaaaatcg aatggatact tggcgaaagg gaagactcat ggacagtcat tggttcatag
     3241 aaatcaaagt ttttttgctt ttcttctttt gtaaaagtat cattgaagaa ataaatcccc
     3301 tgtagtacat ctgcctgctt gatgaagcaa gatctaagga ttttgtccca agaccaatgc
     3361 tgattcagag gaagatcgct tgtgggaata tcggatacag gcatgagatc tttatctaag
     3421 aatgtgtcat gctggacaaa gattcctaat tcttcgtcaa ctgggaagta catgttctct
     3481 gcgatatctt tccatttggc tagttcttct tcgctgatag tgatagcagc ttctttttga
     3541 taagttaaat aattttctcg cgtgtaacgc aagacccaag ctgcgatcgt atttgtatac
     3601 caattgttat tgatattgtt ctcatattcg tttgggccgg tcacaccgtg gatcatgtat
     3661 ttatttgctc gttttgaaaa atggacacgg tctgcccaga agcgtgcgat ttctgctaaa
     3721 acttccagtc cttcattttt caaatattcc gtatcgccgg tgtaattcgt ataattgtag
     3781 attgcatagg caatcgcgcc atttcggtga atctcctcga atgtgatttc ccactcgtta
     3841 tggcattcga caccagtgaa ggtgaccata ggataaagcg cgccttttaa tccttgttgc
     3901 tgagcgttgt ggattgcttg cggcagttga ttatgccgat atttcagcag attcttagtt
     3961 acttcaggtt tggctaaagc aagataaaga gggacagcat acgcttctgt atcccagtaa
     4021 gtggctccgc cgtatttttc tcctgtgaat cctttggggc cgatattcaa tcgttcatct
     4081 tcgccgtagt aagtagagaa tagttggaac aaattgaatc gaataccttg ttgtgcttct
     4141 tcgtctcctt cgatgaccac atcggcaagc ttccatcgtt ctgcccaagc cgctgtttgc
     4201 tcttcttttg cttggatata attgtttgtc tggttcgtta attctgagac agctttttct
     4261 gcttgctgcg cttctggaat atctctacta gtaagaacga taatttcttt ttccactgac
     4321 catgtctcac cttgagataa ttctgcagac aagcaaccat gtaatgctaa agtatcttcg
     4381 tgatagtcag ggatgactga ttttccatta acgaaatggc gcattgctgc agtaacagta
     4441 aattgttcaa tcccaaagtt gtttggaata gttttagtcg tcaaatagcc gatttcttct
     4501 atagttccac gatcaatctc attccaaaaa tgttcatcat agttgctgtc ttcgttttga
     4561 acatttccat ccaattttga tacgagtttg actgttccgc taccttcaag catttctata
     4621 gttaaataga tataagctga ttcttttttg acaatgctca gaaaacgttc gaaggaaatg
     4681 cgtactttat tagtagaagt agtgattgtg aatgtacgag ataatacacc atttttcata
     4741 tctaattccc agtaaaagtc ttctggttcc aaagaagcca agtcgatcag ctgatcgttg
     4801 atcgaaatat ctatcgcgat aaagttcaag gcgttgatca cttttccaaa gtattctgga
     4861 taaccatttt tccaccagcc gacacgtgtc ttatcgggat accagacacc cgccaaataa
     4921 gtaccttgat ggtggtcccc tgagtaagtt tcttcaaagt tcccgcgcat ccccatataa
     4981 ccgtttccaa tacttgttaa agattcttgc agtcgaagat tttttttatc taattgtgtc
     5041 gtgctgattt tccatggatc aatagcaaat agtcgtttga tctgtttcat ttttctcctc
     5101 ctaatgagct gttttatacg ttcataataa acgcaaccga ttgcacaagt caatagacaa
     5161 aagaaaatat ttcatagaaa aaagcttaaa aaaataaatt tttaggagaa aattatagaa
     5221 gggaacacac gtattatagg ttttatagaa tggtatagac agaaaaataa aaaataaagc
     5281 atttacaaaa aagaaaacgc acgctataat acgtttaacg aaaccgattg cgtaaaggag
     5341 ctaaacggaa tgaaaaagat atttagtttt gaattttggc aaaaatttgg aaaggcttta
     5401 atggttgtgg tagcagttat gccggcagct gggttgatga tcagtatagg gaaatcaatt
     5461 cccttgatca atcctgattg gacgccgctt gtcacaacgg gcggagtaat tgaaaatatt
     5521 ggttgggcaa ttattggtaa tcttcatatt ttatttgctt tagcaatagg aggaagttgg
     5581 gcaaaagaaa gagcaggcgg agcatttgca gctgggatct catttatttt aatcaatcgg
     5641 atcactgggg ctatctttgg tgtcacaagt gacatgcttg cgaatgaaga tgcatttacc
     5701 cacactctgt tcggtacgaa gatcatggtt aaaggatttt ttacaagtgt attggaagca
     5761 ccagctttga atatgggagt attcgtaggg atcatcgctg gatttgtcgg ggcaatggct
     5821 tataataaat actataatta tagaaaattg ccggatgctt tgtcattttt caatggaaag
     5881 cgctttgttc cgtttgttgt tatcttatgg tcaacaatcg tggcattgat tcttgctgtg
     5941 gtgtggccaa acgtacaggc tggaatcaat aattttggtt tatggattgc agaatcacaa
     6001 gaaagcgcac cgattctagc accgttttta tttggaacat tagaacgttt actattgcca
     6061 tttggattgc atcatatgct gacgattcct atcaactata cacagcttgg cggatcgtat
     6121 gagattttat caggcgcaca ggcggggaca caagtatttg ggcaagatcc gttatggttg
     6181 gcttgggcca ctgatttagt gaatcttaaa ggtgcagggg atatgtcgca atatgagttt
     6241 gtgttgcata actggacgcc ggctcgtttc aaagtaggac aaatgattgg ttcttcaggt
     6301 atcttgatgg gaatggcttt tgcgatgtat cgtaatgtcg atcctgataa gaaagcaaga
     6361 tataaatcaa tgtatttttc agcagcgttg gctgtctttc taacaggtgt aacagaacca
     6421 ttggagttca tgtttatgtt tgctgctgtg ccattatatg tcatttattc agtgatccaa
     6481 ggggctgcat ttgcgatggc agatatcttg ccattgcggg tccattcatt tgggaatatc
     6541 gaattgctga ctcggacacc gttagctatc aaagcgggtc taggtggaga tcttatcaac
     6601 ttcgtgttgt gtgtgatcgc ttttggtgtt gttacgtatt tcttagcaaa tttcttgatc
     6661 aaaaaattca actttgctac accgggacgt aacggaaatt acgacaatga cagtgaagaa
     6721 accgttgtat ctaacagcgg aacaggaaca gcagatcagc aagtggtcca gatcattcat
     6781 ttgctgggag gaaaagaaaa tatcaaagat gtcgatgctt gtatgactcg gttacgcgta
     6841 agtgtaaatg atcgagaaaa agtagggact gaagaagcct ggaaacgagc aggggcgatg
     6901 ggattgatcg tcaaagacaa tggagtccaa gcagtttatg gaccaaaagc agatgtcttg
     6961 aaatcagata tcgaagatct gctgcaatca ggagcagaga ttccagagcc agaaatggtt
     7021 tctacaggaa atggacaagc aggtagtaag caatacttag gtatagaaca agaactagtt
     7081 tccgcagctt ctggagaagt gattccttta tctgaagtaa aagatccggt attctcacaa
     7141 aaaatgatgg gtgacggctt tgctgttatt ccaacatcaa gagaagttgt tgcgccgatc
     7201 gctggaaaag tgacaagtat tttccctagc aaacatgcaa ttgggctgga aacgaaagat
     7261 ggtatcgaag ttttgatcca tatgggaatc gatacagtcc aaatgaatca gccagctttt
     7321 gagattgctg tcaaagaagg ccaagaagta ggaacaggaa cgaaattagc tgagatggat
     7381 cttgatgtga tccaaaacga agaaaaagat ccaacgatca tgatcgtatt tacaaacgat
     7441 aaagtagaag aagtagtgat caagcaatta ggtacagtga cagctggtaa agtgatcggc
     7501 tccattaaaa tgtaaggaga ggttgtgaaa aagctgtcct gcatcaagtc ataagaacag
     7561 ccaaacaaaa atagctcctc ctatttttcg tttggttggg cttattaccg agaagcagca
     7621 gtttgaatac tgtttagtgg agaggtcgtg aaaaagctgc cctgcaccaa gtgataaaaa
     7681 cagccaaaca aaaaatagct cctggtccat tgagcttatt actgaggagt tagcaggaga
     7741 acactatttg ctggagaggt tgtgacaaaa attttgtcac aacccttttg tttcgaaatg
     7801 aagacaagga gaaaaccaat gaaattcatg acactcaaca cgcatagctg gcttgagcca
     7861 gaaccagaga aaaaattgca agaattagca gataagatcc tgttagaaga ttatgaagtg
     7921 attgctttac aagaaatcaa ccaattactg gaatctgaag aagtagaacc tgcgaagcta
     7981 atgaagttct gtccggtaaa gaatcaagta cctatccgta aagataattt tgcctaccgt
     8041 ttagttcagc ttttaaagga acacggaaaa gagtattttt ggagttggga aatgagccac
     8101 atcggttatg ataaatatga agaaggaaat gcactgctta cgaaaaaaac attggaaagt
     8161 caggtcctta ccgtctccca atttcaaaag aaagaagatt atcagacacg caagatcttg
     8221 attgggaaaa caaagataga tgatcaggac atttttgtct cgagctgcca cttttcttgg
     8281 tggacagata aaaaaagtgg cttttatttt gagtggaaaa acttggaaaa ctactttttg
     8341 gaaactcgcg taccactttt tttcctaggt gatttcaata atccagtaga ctctcaaggt
     8401 tattatactg taagagaaag ttgccttctt cttcaagatt cgtatgttgt cgcgaatgaa
     8461 aaaggaaaag cagctactgt ggaaaagaaa atagatggtt gggaacaaaa tacagaaaaa
     8521 ttgcgtatag attttatttt cgtccctgaa ggaatgcagg ttaaaaaata tcaacggatt
     8581 tttgatggga tcgatagtcc aatcatcagt gatcactacg gggtggaaat cgaattagat
     8641 gtgaacgaat aaaaaatata acatataaca taaaaaaact gattaaaata aaactctcca
     8701 aacgattata ccgtttggag agttttttga tcggatgtat ttatcccttt tgcctaagca
     8761 cgtaaaagct tgtatctatg ataaataaat aaacatagca aggtaaacca gccaatcaaa
     8821 gtaagagaaa gaatgaaata gaaatagatt ggcgtttgat aatgaagcgt gagctcgttg
     8881 attccttttt gctgcttcac gattggggtc ccgatatctg ttacttcata atcagtcaat
     8941 gtttttccat tttgctgtag cacagtccga tcgtagacga taacagggat atgaacagtt
     9001 ttgtccccag tgtttttcca cttgattgtc aaaagaccgc ctggatgtgt ttttataaaa
     9061 gttgtttcgt tttctagtat ttcttcgtta taccggtcgt atttattgtc ttttgtctcc
     9121 ttatagattg gcagatagtc aggtgtggtt ttttggaaaa cgaacaagct ggtagacata
     9181 tctttgctga agaatgtttt ccttgcttct tccggcgtat cgaatagata agtatgtcga
     9241 ctgacaaatg tttcattttc ccacttttcc agatgctggt ataagttctg gatcgtctgt
     9301 gctgaaaaaa taagaatgcc aaatatactt aaaagacgga accacttttg ttcagaccac
     9361 tggttcagtg aaagggcaag gtaaagtaga agcaatagcg taaatggcac gaaaaatcga
     9421 aatggaaact ggatcaaact aataaaaggc acattttttt cgatcaatgt cgtccatgga
     9481 atcaagctag tagaaagaaa aaagaaaaca agacttgtgt acaacacgat tttttggaat
     9541 aaggtgttct tttgttgaaa gaaaataaaa agcaaaaaac ctgataatat caatatagga
     9601 aaggccttag ggtaatggag ccaataactg ccatccagat ctatcgcctt ttgactcatt
     9661 tctctgttaa caaagggagg aagaatctta ttcccactgt aaacaatagc taatcctgcc
     9721 caaatatttg ctgtcagaac aaaataaagc aagaccgact taatcagttg aagcagtgct
     9781 tttccttttt cagtctggtt aaaaaagtaa taaagataaa aagggatata catcaaagct
     9841 aacatgatcg aagacagtaa atggatctgt gtcataagtc ccactgagac agcgactttg
     9901 ataacaggga actttttatg aaggacgaaa tcagcaatag ggatcataca taaaggataa
     9961 aaacaagtcc cccagctagt gaatccttgg ttgatagacc agtattgaat agaatacgta
    10021 ctcatgaata aaacggctac tggtacactt acccaatttc gaacattgac atatctcagt
    10081 aaaatcagca tagaaaatcc tgaaataaga taaagaatga aatttgaaag aatctgataa
    10141 tgaaaccagc tacctgcaag caacacgatc aatccttgta aataagcgaa aaatgggccg
    10201 taaacggcat tcacgatcct gccactttgc tggaatccat aaagggaagg aaaataatgg
    10261 aaatccccat atttaatttg ttgcgcggca tcatagaacc gattgtaatg gaatggggca
    10321 tcagcaccca aaattagttt atgtgtgaat aaatgaggca tgagaaatgc caaagcaatg
    10381 aaaaaaattg ctaaaaatgg gccatatttt ttcaattgtc gaactccttt gcaaacttta
    10441 gataaattca tcatatatcc tatgcgagag gtaggcaaga aattagaaaa ctcatgaaaa
    10501 tatttatgaa ttttacaaga aaaacataag tgaaagttct aaggagagag gatgcgacat
    10561 aagttttgtt gcatctcctt gttttgaaac agaatttttc ttaatactcg aaacaaagta
    10621 gctttttcat gacctctcgg taaacggtgt tcaatcagct gcttctcggt aataagctca
    10681 ctagcctaga aaatatgaga agctattttc tgactagcgc tcttattact caaagcataa
    10741 cgcagttttc acaacctctt ccttaaacgg tgttcaaaag cttgcatctg cggtaataag
    10801 cccaacccaa caaaaaatat gagtagctat ttttttgggc tgtacttatt acttgatgca
    10861 ggacagcttt ttcacaacct catcggcttt cattttctat ttttttcctg aacccatata
    10921 ataaaagaaa gaacaaaaaa acttgcaagg gaggacacat gtgaagcaga gtaagcaaaa
    10981 acagtctcgt cgacttttgt ttcgtttgtt tttattaata tgtatcgtcg tagggttact
    11041 gatcgcttta tatccatttt atgtggattc tttaaatagt tttattgatc aaaaacgtat
    11101 cgaacaagta caaaaacgga ccgcagctga aattgaagtg cagcgaaaga aaatggagga
    11161 gaaaaaccaa cgattaactg accaaggatt caatcctggt actgatcctt tcaatgaaaa
    11221 gaacagaaat gaaagtacaa catccagtca attagaggaa tggctgatcg gaagtatcaa
    11281 tatacctaag atccaattaa atatttcact ttatgatcgg ctcaatggta ggatccttga
    11341 aaatggagca ggcgtcttgc aaggaacctc tttcccgctt ggtggaaatt cgacgcattc
    11401 agtgatctct gctcacagcg gtttacctaa tcgacggtta tttaccgaat tagatcgttt
    11461 agaaaacgga gacacgttta ttttgactgt tttgggggag aaattggctt atcaagttaa
    11521 aaatatacaa gtggtactgc cagatgacac gtctgttcta acgatttcag aaggagaaga
    11581 cttagttacc ttgcttacat gtacgccgta tatgatcaac acgcatcgtt tgctagtgac
    11641 aggacatcgg attccttata acgaatcggt aaaaaaagaa gaaggaaaag gaaatcagga
    11701 aagaaccatg cggcaatggt ttattcttgc aggaacgata atagctgtag tcatactgtt
    11761 agtgtttatc ggacgactaa tctatcagta tagattaagt aaaaaagtgc ttgatttttc
    11821 atttattatt agtgattcgt cagggaaacc ggtaaatggt agttcattca ttttgaaaca
    11881 taagaaaaaa acacttacta gaaatggtgt gccgttttca gtacaaagcg accatcatgg
    11941 gaaagtcaag ctggatcaat tgcctggtgg aacttatcga atcgtttcag ctgatgatcc
    12001 taaagttgct gtttcttttg gtattagaaa agtaaaacaa gagaagatat acttttttga
    12061 ggggcgaaaa cttgtaaaag agcttcaaaa aaatggtttt tattttaaaa tcaatgaata
    12121 agtaaggaga gaaaaaatga tccgcacaac aacaaaattg tctgccaaag aactggaatc
    12181 tgttctatcg atttggctgc atgctaactt ggattctcat gaattcattc catcaactta
    12241 ttgggagaat caagtagaat ctgttaggaa agctttacca gatgcagtga tttacttagc
    12301 agaaatagat caagaaatta ttggttttgc tggggtgatt gatcagttta tcgcaggaat
    12361 ctttgtgaaa agggaatacc ggcaacaaag aatcggtacg caactaatga aaaaaataaa
    12421 agaaaccaat aaaacactga ctttgacagt ctatcaaaaa aatcaatcag ctattcattt
    12481 ctatctttca caaggtttta caattcaaac acagcaaaaa gatgaagcag taaatgagga
    12541 ggaacttgtg atgaaatgga atcaaaacgc tgatttttga tgaacagaat aacgaaataa
    12601 tgctcccagc ctaatttttt gctgggagca ttatttcatt ttgaagtcac taatttaact
    12661 gtgtgaatat gcagttgtta caatctttga taaacggtgt tcaatcagct gaccctcggt
    12721 attagctcaa aaaacggcaa aatatgagga actatttttc catttgtttc tctaatactc
    12781 aggtcaaaac gctgatttca caacctcttg ataaacggtg ttcaaacggc tgcttctcgg
    12841 taataagccc actagcctag aaaatatgaa aagctatttt ctaactagcg ttcttattac
    12901 tcaaagcata acgctgattt cacaacctct tgataaacgg tgttcaatca gctgaccctc
    12961 ggtattagct caaaaaacgg caaaacatga ggaactattt ttccgtttct ttctctaata
    13021 ctcaggtcag aacgctgatt tcacaacctc tctttcacaa ccttatttta ctcgtttata
    13081 attttcatcg aagtattttc cgctacggat atcatctggc attccatcgt atggttcttc
    13141 gctaataaca tcttcattgt ctatacctgc atcacccata taagtgatcg tagcaaattc
    13201 aggaacaagt aattttggat aagtttcata tttttcacga gctgcttcca tttctgcgat
    13261 atgttcgttt tggaaagtaa cagtgatttc tggatgttct tcaacccatt tagggaaaaa
    13321 gatcattccg tgaagtttct tttcatttgg cataaagtcc aatgccacgt ctgtccctgt
    13381 tggctctgtc caagtgattt tgaatacgcc gtccgtcaat ttaacgatat cagcttcttg
    13441 gtcttttacc caacggcctt tgaccattcc gccatggata cggtaatcaa cagtatggtc
    13501 atttttggca taccattcat attcccaacc attgtcatac gtatagataa agtgagttcc
    13561 aataaaatct tccaattctt taaattcttt catgtttaag catctcctta taaattaaaa
    13621 catgtaataa actacatgtt ttcgattact catttatgat agaatggatt taaagatttg
    13681 tcaaggaggg aaaactgatg gcaagaaaaa atacacttcg atatattttg ttagggttat
    13741 taagtaagaa gaagatgaca ggatatgaat tgaatcaatc gttcaaaaat gaaataggag
    13801 aattttggca agcaaaacat agtcagattt atcctgaact tgcaaaaatg gaagagcaag
    13861 gaatcattca gcatcaagta gagatcacag gtgaaaaatt ggaaaagaaa gtttatgaat
    13921 taacagaaga agggaaggaa caattggcag agtggattca tacacccacc aatgaactac
    13981 cggttaatcg agacgaattt gttctgaaat tgtatttcgt caaagacgtg aatgatccgg
    14041 cattagtaga aattattcag cagcagcgtg accttcatga agaaaaacga cttcatctat
    14101 tagagcgaaa aaaaacgatc tttcctactg aaaaagaaaa acatgaaaat tacggacact
    14161 acctgatttt agcgcatgcg atcaatcggg aaacagaata tgcaaattgg ctaacagatg
    14221 tattagaaga aagtaaccga aaaaaataaa aaaatatccg aacagtgatg gagaattcct
    14281 ttctatatga aagaaacgca gatcaccgtt cggatattct tatgttcaaa caggcctttt
    14341 ttcaagtatt tatgtagcat ctacttatta aaaagcttgg tacttaggag attagtggcg
    14401 tttagagttc ttttaacaac tgttcgtagt cagctttttc atcgacagga aggagcttgt
    14461 aagttaattc gtctgtctcg ttgtcatgaa tgatgtacat cttagcattc tcttctttga
    14521 agttaccgat ttgtaaaatc gtatagcgtt cgtcgatcaa ttcgatatct ttgattgctt
    14581 ttgaaaaaac tttacggaca tggtgcattt tcttttggcg gatttctgcc ttttctgcag
    14641 cttttgacaa agtaaatccg tcatctaaat attttttgat cagttctact tttatgactg
    14701 taggtaaacg atattttcta ggacaattcg catcagcttc gatcgaacga atgaatccct
    14761 tttgttccca ataccttaat tgacgtggag acacacctac gatatcactt aattcactga
    14821 tgccaacaac caattgatca ttttccaaca aacgtttaag ggaagcccca accatttttg
    14881 tcactccttt tgtcctcttg cttcccttaa ttatatccgt attaacttat gtgtcaagta
    14941 ggttgacaaa tagcgaattt aggactaaag tattctagta gtttcagaaa aaattcagaa
    15001 agaaggagaa atatgagtaa caaccaaccc gtagatattt acggaaaacc atataatcgg
    15061 acacttttag ttgttgtctt attaattggt acattttgta ccgttttgaa tcagacctta
    15121 ttgacgacag cttttcctac attgatgaaa gctttcgata tttcagcgtc tgatgtgcaa
    15181 tggttaacga ctggtttctt gctagtcaac gggatcatga tcccaataac agcatggctg
    15241 atcaataaat tcagttcaag aaatttatat ctttctgcca tgacgatctt tttgatcgga
    15301 acgattactt gctttacagc acctaatttt agtacattac taatcggtcg tttgatccaa
    15361 gcttgcggtg tgggagtatc gatgccatta ttgcaaaata tcatgctatc tattttcccg
    15421 ccagaaaaaa gaggatcagc aatggggatg tcagggatcg ttattggact tgctcctgct
    15481 ttaggcccta cattatctgg ttatatcatt gataactacc attggcgtga cttgtttggt
    15541 atggtactgc caatcgttgt tcttgtcttg gttttagcat tcttcctaat gaaaagtgtt
    15601 attccattgt caaatcctag cattgatatt ttatccgcta ttttatcaac gattggattc
    15661 ggtagtttac tttacggatt ttctagtgta ggagatgacg gctggggaag cttgaaagta
    15721 attggtttct tagttgttgg tgtgattttc atcgccttgt tctcatggcg tcaattacat
    15781 ttggaacatc cattcttgga acttcgtgta ttcaaatcat ctacattcac gattgcagct
    15841 gttttagctg gtgtaacaaa tatggcgatg gtaggggcag aaatggtcgt accattgtat
    15901 attcaaaata ttcgtggaga atcagcattc cattctggct tgatgttgtt gccgggtgca
    15961 ttgatcatgg gggctatgat gcctgtgacg ggtgcgattt tcgataaata cggcgcgaaa
    16021 cgtttagcca tcacagggat gttcattttg acagcggcaa ctgcaccatt tgctttcttg
    16081 acaaaaacga ctccagtttt atatatcgtg atcctttatg cgatccgtat gtttgggatc
    16141 tccatggtca tgatgccggt aacgacttct ggtatgaatg cattgccaaa taacttgatc
    16201 agtcatggga cagcggtaaa taatacattc cgtcaaatcg caagctcgat tggtacagct
    16261 attttgatca gtgtgttgac gaatgtgaca aaagcaaata tcccaagcaa atctgtattg
    16321 gataatacgc cattagctta taaagatcag gcaatcaatg ccacactgtc aggttaccat
    16381 gccgcgttta tcgtagcgat catctttggg attcttggct ttattattgc ctttttattg
    16441 aagaaaaaag aacctgttct aatgaaagcg ggggataatg catgattatt ggagttttga
    16501 ttgtcagctt gcttgctttt gctttaacga acgtgttcgc taaaaaaaca tggcaaacct
    16561 ttttatcttt gattttcgga ctaatcttcg tcgcttcact aagtttgatc gtcgctaatt
    16621 tgtccaatca ctttggaatg gaaaaagtaa cggaaacaaa aacagaaaaa attgtttcca
    16681 gtgctgattc ccaaggagca gatatgcttt tgtataaagc tttagggaat ggaaaagaaa
    16741 aagtgtatct ttaccgaaca aatgaaaaac aagaaaaacc aaaagcaact ggtacggata
    16801 acgaaacaaa taaagtagaa aagacagacg gcgatgctga aaaagtgacg aaaactactt
    16861 attgggaata caaaaacgac atgtataaat tctggttcaa tattgctgat aacaatcacg
    16921 aatatgacag ccgagtgaat acattcaaaa tcccagagac atgggtagaa ttaagtacgg
    16981 accaagcagc caagttagct gaattagtga agaaacagca aagtacgatg gaaagtgaag
    17041 caaaagctta tgttcaagac ggtatggtaa aagcaatgac tgaaaatcca aaaatgagca
    17101 aagcagagca agaacaacgt acgaaagcct tagctgctga attccaacaa caagcattcg
    17161 caaaattagt gaaagaagca aaaggcgaat aatattttga acaccatgta ggaggttgtg
    17221 aaaaagctgc tctgcatcaa gcagtaagaa caatcagata aaaatagcac tccatatttt
    17281 tcatctgatt gggcttagtg ccgtagatgc aagcttttga acaccgttta aggaagaggt
    17341 tgtgagcctg ccgtttaact ctgagtcaca aggagcaatt tcaaaaaaca gcttctcatg
    17401 tttgttgact attgtgactt gtgaccgagg agttggcagg agaacaccgt ttattcgaaa
    17461 aaaggaactg cgacaagact tttgtcacag ttccttcttt tttttgctat gctatactag
    17521 atgtaaaaaa taggagaaat aaaatgaggg aaatttattc ttttgaatca aaaatctatg
    17581 cttccgaagt cggcaagggc ggggcatata ttatttttcc gtatgatata agaaaagaat
    17641 tcggtgctgg aagagttaaa gtccaagcaa cttttgacaa tgtgccgtat gaaggcagta
    17701 tcgtgaatat gggcgtgaaa aatccagatg gttcagtctg ctacatcctt ggactacgaa
    17761 aagatattcg taaaaacatc ggaaaagaaa tcggtgatat tgtagcagtt acagtgaagc
    17821 aaaaataaaa gaggttgtga caaaagacgt gtcacaacct cttgataaac ggtgttcaaa
    17881 agccagtttc tcggtagtaa gtcaaattta tgcaaaaatg tggaaaccca tgtttacaaa
    17941 atttttctta ctactcgaaa cgaagcggct ttatcacaac ctcttgataa acggcgttca
    18001 atcagctgtc cctcggtatt agctcaaaaa cggcaaaata tgagaagcta tttttccatt
    18061 tttttctctc atactcaggt cataacgctg atttcacaac ctcttctttc ataatggttt
    18121 ttcaccatct ttataataaa ctggttcttt gatatggaaa tctatttttt ccaaccaatc
    18181 taaaatcttg taacctaact cttctgacat cggaaaagag gcgttgattt gtgcattgga
    18241 gatatggtca acatggatac cggaagtgat cgtacaactt cccggaacgg cagttttgat
    18301 gatcacagct attttttcgg ctaagacatc gtctttatgg aaccgaccat cgtggctagg
    18361 gaaacgtaca gtttgcatct ctgtatcacg agaaaatgta gtgactgttc cgatatgtgg
    18421 tgtatctccg cctgttaaag tgatcaataa gtctttaccg attactttaa cagcagcttg
    18481 gatcgtgaaa cctagtttgg ttacttcaac tatcgtttct ttttccatat taatcaccct
    18541 gccaacgttt tgaatgctca tttacaattt caaattgatc caaaagtttc attgtatggt
    18601 gattaacaag atcttggatc gtttgaggct gattataaaa agcaggaatt ggtggtatga
    18661 tttgcacacc tagtcgtgct aatttagtca agttttccaa gtgaatggca tttaatggcg
    18721 tttcacgagg aacaatgact aactttcgtt gctccttcat tgttacatca gcagcacgtg
    18781 caatcaggtt gtcgcctaaa ccaacagaga tacctgcgac tgttttcata cttgccggta
    18841 cgatgatcat tccatcggtc aaaaatgatc cgctggcgac agcagcacct aaatctttgt
    18901 ttgaataatg gtaatcaaac aggctttcga attcagttag tgataagtcg gattccagct
    18961 ttaagttctg ttttgcccat ggactgatga ttccgtgtgt ttctatcatc ggatattctt
    19021 ttagtttctt cactaggttg atggcataaa tggtgcctga agcgccactt acaccaatca
    19081 cgattttttt cttccgttgt gccaattgtt ccattttccg cactcctttt tatgatgtca
    19141 aaacagttgc agatcattca ttatttcaaa tatttttccc aatcttctac ttcttggaat
    19201 tttgcacgta caaaatgttc tttcatatcg aaaggaactg taccgtcaaa gatagttttt
    19261 gcacttatcc cacggaaacg aatagagcca ggattatatt ctggtaattc tgatgggtcc
    19321 aatggatggt tcctcattcc tgggatcacg atgatatctt tatctccttg gaaacgagtg
    19381 ttgaaagtcc aaactacatc gttcatgtcg aaaatatcaa catcttcatc gactaaaatg
    19441 actgtcttca attctttgaa ggctgataaa gcaagaatag ctgcttgacg ctgaatacct
    19501 tcatccgctt cgttttcttt acggatttgc atgatggtca tcaatttacc accacctgca
    19561 ggaggattgt agacatttac tacttttcct ggaatagctt tatcgaccaa ggcaagaata
    19621 cttgcttctg taggaatacc ggccatagat acgtgttctt cactgggacc aatcgttgtt
    19681 tgcatgattg gattgtcttt tcggtgagta actgctttga ctttcactac ttgtacagct
    19741 ggattagcat ccccagtata gccaggaaat tctggcattg cttttcctga gttcgtgttg
    19801 atatcttctt gcattgtttc atttggcatg atttctgctt caatgatgaa ttcagcacga
    19861 gcaataccca cttcatcgac tgctatacca tcaacgattt gaataggttc gttacgcaaa
    19921 gctcctgcac accatagttc attgtagcca agtggagtgg taggtggttc gaaagtcgtg
    19981 ccaatggcaa ttgctggatc taaaccaata ttgatagtga taggcattgg tttattcaag
    20041 gcttcgaatt gtttttggaa gtgaccaatg tggcgtccgc caggcatgat gtacataccg
    20101 atcgtatctt tatcttctag aaccatacga tggatcgtta catcgctcat tgttttttct
    20161 ggatctgatc ctaagactac acccattgtg atgtatggac cagcatcttc aggagtattt
    20221 gtaggtgcag gcaaaatgtt gcgaatatcg aagtctgcat cggtagctag atgaacgact
    20281 tcttgtgctg gagcgtctgc tttgtctact ttcacaggtt tgattggatt ttctacagcg
    20341 tctttcaaga aacgaccaag tgttcgataa tcatggtgca aaatttcacc tacacgttta
    20401 cgactagcca ttgttccgat gttcacacgt gtgccgggga aacctttgat attgttgaaa
    20461 gtcatagctg gtccttcttg agtcggacgt tttactgtac cgccagcacc gatataacgg
    20521 taaacaccag ataattctgc ttcaggatcg atttcaatat ctgtttcgtg atattgacct
    20581 ggaagtgttt ttagttcttc gatgactttt cttaaatcat acggttgatc tgtcatgaga
    20641 gattcctcct tagttgtctt tacctatcta tagtaaaagg tgaaaaagag gaaaacaatt
    20701 caacttgttc ggtaaagtat tctacaatgg aatggatgcg tttttttgat aatagaataa
    20761 actatgatat acttatcact aaaagaaagc gcatacttag tgttggagga aggaaagtga
    20821 aaaaaatgga ggagtcattt cctaaagcag taaaagtgga aaatatagcg aatattttga
    20881 aagttacatt tgaaaacgga gaagtaaaat acgtgaaatc tcattggaca gaagagataa
    20941 ccgatgcctt gcaatttgga aaaaaaggaa gaggaaaaag aaaaaatctt ctcgcacttt
    21001 ctcgtaatat gtggattggg actgaagtaa cgattgaagc agatggaaca gtattcataa
    21061 atggaaaaga caggtatacg ccagaagagt tgtggtacaa aggaaagaaa agtataccag
    21121 aattataaaa aataattaaa aaaaacagcg cgaaacaagg aacatattac ttcctcgttt
    21181 cttgctgttt tctactattt cagcgctctt atgactcaaa tctaaatgtg gttgtcacaa
    21241 ccttattctg cacgcaaagc gatagcggcg tcttttttcg ctgccattcg tgcaggaaga
    21301 tgaccgccaa gcatcgtcaa tatagtagag acgatcacta gaataatcgc atggacagga
    21361 tttagttgag caacattttt tagatccgtc atgttgtata agatgctatt gatagggaac
    21421 gtagctagcc atgcaataaa cacacctaat atcccagaag aaatacctaa aatacacgtt
    21481 tctgcgtcaa atacgcgagt gatgtctttt ttacgtgcac ctaaagcttt tagtacaccg
    21541 atttcttttg tccgttcaat cacagatgta taagtaatga tactgatcat gatcatactt
    21601 gttactaaag agatccctgc aaaagcaata aggacataag tgatagcatc catcaatccg
    21661 ccagtcagtt cagtcatcgt tccagctaaa tcagtataaa tgattttatc ttcatctgat
    21721 ttgcctttat tgtaatcatc tagataatcc aagatctttt ctttgtcttc aaaattgttc
    21781 ggataaatca tgatacttga aggcaagctg tctccaccta aataactaag caatgtttgt
    21841 ttggcatttt cgtcaacttt ttcagtagtt aagacattta caccactgtc tctttgagct
    21901 ttgacgattt ctgattcttt gttttcgttg acgatttgag tcgttaattg atcgctataa
    21961 gcgattcctg gagataagag attcattgta gaagaagatt tcacgcgtag gatccccgag
    22021 atcttcaatt catcagaagc attctgatac atcgcatcat aatctgtatt agggataaaa
    22081 ttcccagttg gaagttttgt atagtaagta ttgttgttta ctaatttgaa tgttgtacca
    22141 acgatatcat caaaatcaag tttttcgtct tctttcacat caaatccaag attcttcaat
    22201 gcgttgatat tagtattatt attgccgtct acgatcagca cgacatctgt tgctgaggct
    22261 ggataacttc cggcaagtaa agaataattg tcttttaaaa agttttcttt gctagtgtca
    22321 agctgtgtag ggaaacttga cactcccaca cctgtcatcg ctgacatcgt actagataaa
    22381 gaaagagatt ccgtatcagg attttgattc gagaagctga caggctgtac tttgccattt
    22441 acatcacgta aaagattgat tcctgtagta cgggtaaatc cgatattatt acttaagtta
    22501 ggatcgatgt ctgttacgta atcgacgtat gtttgatcaa tcttattcgt gtgctgtgct
    22561 ttatcttctt cgctgacttt tgcagtaatc gttttgctgt ctggataatc cgctttgctt
    22621 gcacccaatc cggcatcgtc acgagtctgg ttagtcgtta ccttagaaat agtaatcgga
    22681 aatttcgcca tcgtttcagc ttgcgtgtta tcgatttgtt tttggaatcc agaagaaagg
    22741 gacagaacga tcgcgattcc gatgatccca atactggaag caaaggaggt caagaaagta
    22801 cgtccttttt ttgttcggat attgttgaag gaaagcttta acgctgtcca aaaactcatc
    22861 tttgttctgc gtaagttaaa ttgatcatct tttggtcgtt cgatgtgagg atgggaatct
    22921 gttaagatct taccatcaga aaattcaatg attcgatctg cgtattgatg ggccagttca
    22981 ggattatgtg tgaccatgat cactaatttt tctttcgata actcttggat caattccatg
    23041 atctggatac ttgtttctgt atctaacgct ccggttggtt catcgcacaa aaggatatct
    23101 gggtcattgg ctagtgctcg agcgatggcc actcgctgca tttgtccacc agataactga
    23161 tttggctttt tatgcatatg atttgtcaag ccgactcggt gcaatgcatc ttctgcccgt
    23221 tttcgttttt cgtctttaga aacaccactt aatgtcatcc caagttcaac gttttcaata
    23281 atgcctagat gaccaatcaa gttgtaactt tgaaaaatga aaccgataga gttgtttcgg
    23341 taggcatccc agtcactgtc cttaaagtct ttagtagact ttccgttgat taccatatca
    23401 ccggaatcat aattatctag tccaccaatc acattcagca tagtcgtttt accagaacca
    23461 ctaggaccta aaatcgctac gaattctttt tgtctgaaag cgacagacac accatccaat
    23521 gctttggtgg tggtttcgcc gactttataa tattttttta tatcttttaa ttgaagcata
    23581 atcacccttc tcccgtattg aaatattcgg tatactaata agtatatcag aacaatgatc
    23641 gtagtatacg aaataaatgt taactgaaga tgaactacaa gaaaaaatct agaaattttt
    23701 caaaaaacag agggagatca atgaatcgta ttttagtagt agaagatgat ccgcaattac
    23761 agttgcttta ccgttctgtg ttggaacgag cgggcttttc agtcatcacc gcattgaatg
    23821 gagaggatgc gctgaaaaaa ctagaagcga cacgtataga attaatcatt acagatatca
    23881 tgatgccgaa aatggatggc tatgacttgc tagactcatt acgtagcacc agatttgaca
    23941 cacctgttct aatgattacg gcaaaggccg attttgagga taagaaacgc gggttcaaat
    24001 taggagcaga tgattatatg acaaaaccca tcgatgtcaa tgagatgatc ctacgtgtgg
    24061 aagcattgct tcgacgttca aagatcaatt acagcagtag cttgataatc ggacaaacaa
    24121 aattagagct agatgcttat acagtgttac aagatcagca ttcgttgatt ctgcctcaaa
    24181 aagaatttct gcttctgtat aaattactgt cttatcccaa caagatcttc actcgccaac
    24241 agttgatgga tgatatttgg ggattagata cgaatacaga agaacgaacg atcgatgtac
    24301 atatcaaacg tttaaggacc cgttttgaaa agacggaaga ttttcaaatc atcacagtac
    24361 ggggactagg ctataaggcg gttatttaaa gatgaaaaaa aagctatttt cacaattatg
    24421 gatctatttt gctagtattg tcttcatttc gatcttagtg acactgctgt gttttctcgg
    24481 ttttattttc ttattgtctc gacattctat ctcgcctgct gaatcggctg gaaaaccaac
    24541 gttatacccg ttattcgtct ttgcggggtt cagtatggtc gtgggtacag gaatatcgat
    24601 ttttgttggg cggcgtatcc tgcatccaat cagtgcgcta gggacaaata tgagtctggt
    24661 agcaacggga gatttttcga ttcgaatgga tgaacagcag aaagtagcag aagtacagca
    24721 actgtataaa gatttcaacg ttatggtcca agaactcaat agtatcgaga cactgaggaa
    24781 tgactttgtg tccagtgtat cccatgaatt caaaacacca ctagcaacaa tccaaggata
    24841 tgttcaattg ttacaagccc caaatctctc tgacgaagaa cgccaaatat ttttatatcg
    24901 gattatcgaa agtatcacgc agctttcaca attaacagag aacatcttaa aattgaacaa
    24961 actggaaaac cagcgtatcc aactggaaaa gaaagagtat cgattagatg aacaaatcag
    25021 agaagtaatc gttttttttc agcctaaatg ggagaaagaa cagctagaat tggatatcga
    25081 acttgctgca gtaaattaca caggcaatga agagtttttg taccaagtgt ggctgaatat
    25141 catggataac gccataaagt acaatcaaat caatggacag attcatatca aactatttga
    25201 gacagccaca gagattgtac tggaagtgac cgattcaggt gtaggaatga atgaagagac
    25261 cagagatcga atgtttgaaa aattttatca aggagataca agtcgtcaaa tttctgggaa
    25321 tgggctagga ctttcactgg ttaaaaaaat tctagaactg catgatggac gtattgatta
    25381 tagcagtatc gaaggagtag gaacgacagc aatgatacgg ttaagtaaac aataggaaaa
    25441 agaataaaac ccctaaaaat tctattgaag gtttttaggg gtttttagtc gtttttttgt
    25501 gattagggaa atgttcttac ggttcttttg gcataaaaat cgctgctttc ttattgaact
    25561 acgagaaatg ttagaggtgt cattgaaaca aggacatgat gcaagaaaga gagcgaaagt
    25621 catgcgtcgc tctctttttt tgggtggata gatggacaga aaatgtaggg cttagttttc
    25681 ttcttgattt aaatactccc aaaatgtatc tgaagccaaa gaatgctcac cgactttacg
    25741 agtaaatgca agataactct ctgttgttgg agaaataggg agaatcacag tattttcttt
    25801 taatagattc ttgactgttt tttccataac aatagcaatc cccatgtcat ttgcaatcat
    25861 attgatgatc aagtcgattc ttgctccttt ataagagatt tttggttcaa atccagcttc
    25921 gcgacacaga tctagtacag gttgatacaa gttcgtagtg gggccaagga gcaaaaagtt
    25981 ctcctttttc agttcgctta gatccaattt ctttttacta gctaaaggat gatttttagg
    26041 tagaactgct acaaaatcgt ctgtttcagt aggcaaccac tcaatcgaac ttggtggggc
    26101 ctggaaactt ctagcaaagt ggatcgtgtc actatgttca ttggcgtcat tgtaagttaa
    26161 ttcgacactt tccacttctt tcaactggac tgtaaattca ggatggcgtt tcaaaaactc
    26221 ggtgattttg gaaaaacctt tataattgat cattgtcggt atcgttaaga tatttaatga
    26281 aagattgttg tctttcgtat aggtttcaag cacttcttgc atagcatggt attgttctac
    26341 gacatttttt acatatggga gcaataagct tccagcttcg gtcaattcga tttttctatg
    26401 ggcgcgttcg aataatttga cgtctaattc tgtttctaac gaaagaatct gtttagaaat
    26461 atttccttgg gtggtgaatt gtcgatcagc agttttggtg aaattcattg tttcggctaa
    26521 atcaagaaaa acttcgaatt tatggatatc catcatattc ctcctactta ttccaataaa
    26581 gaatacttta acacaaaaaa tgaattggtg taatcttctc tgtctgttac aatctttctt
    26641 gcagcgaaag caataattac agaaattttt ctgatttttt tcgcttcgta gaaaaagaga
    26701 ggagtttttt gatgccaact ggagttttga tcaatgtagg ttccgttttg tttggcggac
    26761 taattggcgg attagtagga aataaattaa gtgaacattt taaagcacag ctgacgatgg
    26821 tttttggtgt gtgttcgatg gggatgggaa tctattccat tgcgccgatg aaaaatatgc
    26881 cggctgttat ttttgcttta gtgataggaa cagcgattgg tttgattgtt catttaggta
    26941 atgggataaa taagggggct gcgctgatgc aagtacctat ttctaaaatc ttccctagtg
    27001 aaaagcttgg tatgacccac gatgaattta tcagcacatt agtgacggtc attgttctat
    27061 tttgtgcaag tggtacgggg atctatggaa gtttagattc tgggatgaca ggagacagta
    27121 cgattttgat ttctaaatct gtccttgatt ttttcacagc agctattttt gcgtgtaatt
    27181 tagggtatgt cgtttctgtg atagcaattc cccaattcat tattttttat attttgttct
    27241 tattggcaaa atttatttat ccattgacta caccagacat gatcttagat tttaaagctt
    27301 gcggcggatt cttgatggtc gctaccggtt ttagaatgat caacgtgaaa atgttcccag
    27361 tagctgacat gatacctgca atgatcgtta tcatgccact gagctggatg tggacaaatt
    27421 ggattatgcc actgttataa taaaaatcaa agagaagcca ttttttgctg actaaaaagg
    27481 atcaaatctt ttagtcagtt tttttgtatt tgacaaactg attttgaaac tatattatat
    27541 gttgtataat atagattgaa ataaaatatt acacttgaga atagaaggtg acgtaatgca
    27601 catccagatt ccaactgttc ttcttgatgg tactgtgtta gcagcattaa gcaaggaaga
    27661 tatgtatggg tatgccttaa caaaaatcgt acaagaaagt ctctctgtca gtgaatctac
    27721 actatatccg gttttgagaa ggttgaaaaa agaaggatat cttgagacct atgatgaacc
    27781 ttttgaaggc agaaaccgtc gatattactc gttgacacca atgggaagtc gtcatttaga
    27841 agaaattatt gatgaatgga ttgtttttcg agattcttta gaccggttat tggaggagag
    27901 cacaaatgaa tgaatatttg aatgaagttg tggatcatct tcaagaaatt cctgaagacg
    27961 atcgttttga tttgatccag tattatgagg aatatttttt agattctgga aaaacattag
    28021 atcagatcat tgatgaatat ggtacaccaa agcagtttgc cttaaaatta aaaatcagtt
    28081 acttttcaga agaagaacaa gcagaaaacg agttagtgaa aaatccaaaa agacaaattc
    28141 gcctgatttg gttaatcatt atcggtttat ttgcttctcc tgtcctcatt ccactagcac
    28201 tggggtttat attggttatt gggggactat tggttgcttt actagcgctc atttttagta
    28261 tctatgtttt atgtatcagt atcttaggtg ttggcctatt catgatcatc tcaggaatca
    28321 gtgtgtttgg acaatcgatt ctgagtggat tattctttat cggtgtcggt ctgttcgcca
    28381 caggaagcgc agtatttatt tcgccactgt tgctgaaagg aacaaaaggg cttttttatg
    28441 tcatgatgaa ctttgttaaa tggatgggac gacgttttat tacaaaaaga gatctgcatt
    28501 cagcgggcgt ttgaaggagg acacataaat tgagattgaa acattttttg attaccggta
    28561 ttggtctgat gcttactggt ggcctcctag caggtgcaac ttatacatta ggcgctcaaa
    28621 agagtctgac ttgggataat ggtcctcggt tgatcgatat ggttactgag acaaaaaaaa
    28681 tcaaggatgc aaacaaaatc gtcatccatg cagaaaatca aacagtttcg gtcatacgcg
    28741 gattggattt tgagataaaa acgacttatg ataagacaga aaagccagaa ataaaggaga
    28801 aaaatggcgt gttgactgtg aatgcagtca aaaaatcaac aggtgcaatc attagtttag
    28861 aagacacaag tgcacaaatc actattgttg tccctgcaga tcatgaatta tctgaattga
    28921 caatcgaagg gaataatagt gcaattgata tcaacgaagt atcaatcaaa aaagtgaata
    28981 ctaagacaca tgatggctgg gtatcgttca atgaatttac aggaggaaca ataactgcga
    29041 aagatgaatt aggctcactt cgactagatg aggccaatgt ggataacttg atcgtcacag
    29101 gtgaaaacag caacttccat ctagaagaca gtttgatcag caaagaagga aaagtcatcc
    29161 taaacggtgg taatttatct ttgcatgaga tggaaaacag tggctatact atccaaacgt
    29221 ctggtgaatc ttatattgaa aaagactacc agccaataac aaatactttg ttagaacaag
    29281 gacagaaaaa gctaaagatc actgctaaag acacatcgat caatattacg acggatcaag
    29341 aggacaatga aacagattga tcctgtactc aactggatat tttaagaaaa aacagcaaag
    29401 atccttccaa tctttgctgt ttttcatcgc ttaacgcaca taactatagt aaaataagaa
    29461 agaaaatatc taaaaagaaa acagggtgaa agagtatatg aaggtagaag aaggtcaaag
    29521 agaaaagtta aagacagaaa tggaaagatt acatacttat atcactcaac taagccaaac
    29581 cttctatgat ccagacaaag aaaaagtgat ggttaattac ccgaacaatt cagaaggtcg
    29641 ccaattagag caagtgtacc atgaagtttt caaacattta ttgacggtga agaaagagct
    29701 ggattattat tctttaccga ttatcgatac aggaatattg aagtatgatg ggaagaagga
    29761 acgatttatc tttaaatctg ttcgggaaga tttgcctctt tcagcaggga tggatctaga
    29821 ggtcttggta gaagactatt ttacagaaga aaagcactgg gttcgaacaa aattggatta
    29881 tttaccgcag gcagccggag ggacacaggc aagcggttgg tacatcactg aagacaaaga
    29941 gttagaacta gaaggtgtaa tggcgcgcat tcgaaaaaaa attaaaaaag taacattaga
    30001 tatttattga aggataaagg agcgcaggaa gtagcatgag agaaaaaaga gcattttata
    30061 tcaatggtta tgcagggatt gtcggattgg tcgtattagc tttagttgga ttgtttttct
    30121 tctatttagg catgtggcaa gcgaaagttt gggcactttt tttaagtatt tttctttggt
    30181 tgatcacgtt attgttgtta agttcggcaa ctgtagtcag tcctaatcaa gcaaaagtaa
    30241 ttttgttttt tggacaatat ttaggtacga ttcgagaaaa tggctttttc cttacgatac
    30301 ctttggcaca aaaaatgact gtttcgttga aagttcggaa tttcaatagt tctgttttaa
    30361 aagtcaatga tttggatgga aaccccatcg aaatctcagc agtagtagtc tttaaagtcg
    30421 ttgatacagc aaaggcatta ttcgatgtag cgtattatca agattttgta gaaatccaaa
    30481 gtgagacagc cattcggcat atcgctagcc aatacccgta tgatacattc aatgagaatg
    30541 atttgacgct tcgaggaaac acgacggcag tgtctgacga gttgcaaaaa gagctgcaag
    30601 agcgtttagc agtagcaggt gtcgaagtaa tcgaaacacg cttgaaccat ttagcctatg
    30661 caacagaaat cgctagtgcc atgctccaac gtcaacaagc aaaagccatt ttgtctgctc
    30721 gacaaaccat tgttgaagga gctgtcacaa tcactcaaat ggccttagag caaatcgaag
    30781 atggacaaga aatcaatttc accgatgatc ggaaagtcca attgatcaat aatttacttg
    30841 tctcaatcat tacagacaaa ggaacgcaac ctgttatcaa tacaggcgac atgaaagacc
    30901 gtaagtgaca tactttttgt aagataggaa gaaggagttt aggacggatt attgtcttga
    30961 actctttttt tagttgtttt aaagaaaatg acaaaattga aagaagaatg atagttgatt
    31021 cgaaggcaga attgttcgct tttttctata atcagtatat aaagtaagag agaaggggaa
    31081 aaagtgaaaa aacttctgat cggtctactt gttttcatcg ttgtggtact tgcaggggtg
    31141 aaaatcgcag attacgtagt tatgggtgga gaagaatact atgtacaaat tacgacagat
    31201 ggtacaaaaa cagtttcaaa atcagactct ggacaagaaa cagtcaacta tagatatatc
    31261 ctgcctggct atacgaaaga gggtaaggaa aaagaactgg acttcaaggg acaattgact
    31321 cgaccgcttc gtaaaggagc atatttaaaa atcacctgga acaaaaataa aggtgtcact
    31381 tcgtatgaag aagtcgaaaa aaaagacgtt ccgaaaacag cactggaaaa actaattaaa
    31441 gggtagggaa agaaatgaac aaaatagtcg aagtacagaa tgtaacaaaa gtatacggaa
    31501 aaaacaatga gaaaaagacg caagcattaa gcggcatcag cttcgatgta gaaaaaggcg
    31561 aatttattgg gatcatgggc gcttctggtt ctggtaaatc gacacttttg aatattttat
    31621 ccacattaga taaaccaaca gatgggcata tccgaatcaa tcaaaaagat gtgaccacat
    31681 taaaaggaaa tcaactagca gattttcgtg cgaatgagat tggctttatt ttccaagact
    31741 tcaatttatt agaaagcttg acagcacaag aaaatatcgc tgttcctctt tctttacaag
    31801 gcgtcaaacc aaaagaaatc aagcaacgtg tccaaaaaat tgcagaacgt ttatccatct
    31861 ctcatatttt ggaaagctat ccttctgaga tttctggtgg acaaaaacaa cgggtcgccg
    31921 ccgcacgtgc attgatcaca caaccaacga ttctattagg ggatgagcct acaggtgcgc
    31981 tggattccaa aagtgcccgg gatcttttag atacgatgga cgaattgaat acaaaagatc
    32041 atgtatcgat tcttcttgtg acgcatgatc cgttttctgc aagttattgc caacgtattt
    32101 tattcatcaa ggatggcggt atccatcaag aagtgaaacg tggagatcaa agccgtgatt
    32161 ccttctatcg agaaatacta tctattcttg gaaacttgga acagtagggg gagattgact
    32221 atgctttgga aattatcact tactgggatc aagagccgtt taagagacta cctggtgtta
    32281 ttctcaggat tagttatggc atctgctatt ttttacatgt ttgaatcaat ggcaagcaac
    32341 gaagcttttt tgaaaagtaa tacgatcgtt gcggctacag ttatcatttt ccgattcggt
    32401 tctgttttac tagggatcat cacattcgtt tatattttat atgcaaattc ctttttgatg
    32461 acgatgcggc aaaaagacta tgcaatgttt atgatgctag gagcaaaagg cagaaaaatc
    32521 gcacagatga ttttttctga aacattctta gtagggatcg cagctacttt agtgggttca
    32581 gctgtcggtg taggattgac aagtatcgtc caccgattat tagtggatca gttagatctc
    32641 aatatttcgc attttacacc ttttagtatt cacgggttgt tgatcactgt tttgtttttt
    32701 gctgttttgt ttttattagc tgctgttgtc aatgcttttt cgattgtcaa aaaaccgata
    32761 ttagcattga ttcgtgcgga tcagacacca acaagaatca agcagcataa attcttgttt
    32821 ttccttgaag tagtactggg aattgctttt ctaggctgcg gttactatat gatgaaacac
    32881 gtggggacct atcaagtctt tggtatagga gtagccttag ttacgatcgt attaggaact
    32941 tatttcattt tccattctgt gatcattttc tttttatcat tactaaagaa atcagaacag
    33001 atttcattga aaaaattgaa caatttcaca ttgtcacagt taaactttcg tattcgtgaa
    33061 tatacacaaa tgctctcaat ggtcgctatg ctgtttgcct tggcactggg cgctttgacg
    33121 gtaggattag gttttaaaaa tgaaattgca gacttgacag aaaacaattc tggatatgat
    33181 ctagtgatga ataatcctcg ggcagaagat cagcaaaaaa tcaaagaact ttcaccaaca
    33241 ctttctgctt cttatactca aaaagaagat gcgggaacga tttactataa tgcaagtgaa
    33301 tttgcggctc aaccattgat catgataaaa catgaagatg gaacaccgcc gaagatcacg
    33361 aaagaaaaag ttcctgctga aaaaatgaat gaactgactg tacaagagga acttcgaagc
    33421 tatgaattgc cggaacagca agaaaaagaa atcaaggtag tcagtcaatc agaatttgat
    33481 caactgaact tgccacaatc cactttacag ctagttcagg taaaagactt ccaagcaaac
    33541 ctgaaaccaa tcgaaacact tgttgctcaa aataaaatga acaatccatc tttgcaaaaa
    33601 gtagagtaca gcaaccagaa atatgaaatg tatgaagtgt ataatggtct attctctggt
    33661 tttgaattta tgggattctt cctaggttta gctttcttga ccatgcttgc tagctgtttg
    33721 atgttcaaga tcttgtcagg aagcaagagt gacattgctc gttatgaaat gcttgaaaag
    33781 ataggaacac gacgcgggtt gcttaaacaa tcgatccgta gagaagtagg cgtgttattc
    33841 ttagcaccag gaatcttagg tgtagtccat gtcttattcg gattacaaat gtttggtcta
    33901 ttcatgcaaa atccatacaa agatatttgg gttccgttta cgatcttctt cgtattgtat
    33961 ttcatctact atgtactgac gacatggtta tatactggaa tcgtattgaa aaagagattg
    34021 tgaaaaagct gtcctgcatc aagtaataag aacagccaag caaaaatagc tcctcctatt
    34081 tttcgtttgg ttgggcttat taccgcagat gcaagctttt gaacaccgtt tgttcggaaa
    34141 aagaggttgt gacaatattt ttgtcacaac ctttttttca cggtctttta ttagaatata
    34201 gtaaattttt tctcgttact cacggaataa gctgttaaga aaacggtttc catgtatact
    34261 ggaatcagtg caaatgaaag aaaagagggt gcaaggaaca tggaaatcaa tgaacaaaat
    34321 tttggcgaaa actatcactt gattacgatc acgaatcaaa atgggacatc tttgtctgtc
    34381 agtgatcttg gggcacgggt tgttcatttt caaacaataa tcgataatga aaaacgagag
    34441 ttgatcttag gttttgatga agcaaaagaa tatctagaaa aagaccctta tatcggtgct
    34501 tcaatcggac gtatggctgg acggattacg aatggcacat tcaaattaga tgatgaaacg
    34561 ttcgaagtaa aaacagaccc ggacactggt cattgtttac atggtggtgc acctagcttt
    34621 gaagccaagc agtggcatta tacagtcatc aatggtgaaa acgaagcatc ggtcattttc
    34681 tatcagacta gcccagacat ggaaaacgga tttcctggaa ctttagatgt agaagtacgg
    34741 tatacgctga cgaacgatga tacatggcga gtgacggtcc aagggatcag tgaccgcaaa
    34801 acagtattca atcctacaaa tcatgtctat ttcaatttaa ccggtgatcc agcacagtca
    34861 atcgacgaac atatactttg gttgaatagc cgattatttg ctacgctcaa taaagataca
    34921 acgcctacag gagaagtagt ttcagtaagt ggcacagcat ttgacttcca acgtcctaaa
    34981 aaattaggtg aggtctttgc cagtgatttt cgccaatcaa tgatagtggg cggtatcgat
    35041 catccatttt tgttgaaaaa acaatctggt ttactaaatg ctgcggaatt gacaagccca
    35101 gatgaaaaag tatcgatcca agtaaaaaca gatgcttcag gaatcgtgat ttttacagca
    35161 aattttggag aagatggacc ggaaatgcgc gggaataaat tagtaaatca tggcggtatc
    35221 acatttgaga ctcaagaact gccaggagcg gagcgacttg aaagttttgg agatgtcact
    35281 ctggaaccta accaagtacg cgagtttgta acggaataca aaataaatat aaagaaatag
    35341 aataaattaa aaagggagtg tgacagtgtc acatcccctt ttta
//
LOCUS       DACDLM010000026        34868 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.026, whole genome shotgun sequence.
ACCESSION   DACDLM010000026 DACDLM010000000
VERSION     DACDLM010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34868
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.026"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..107)
                     /locus_tag="IV356_001291"
     rRNA            complement(<1..107)
                     /locus_tag="IV356_001291"
                     /product="16S ribosomal RNA"
     gene            26..169
                     /locus_tag="IV356_001292"
     CDS             26..169
                     /locus_tag="IV356_001292"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9014990.1"
                     /translation="MEKEAFDLHVLGTPPAFVLSQDQTLIKSSNNLAIVKLNLFASIL
                     LAC"
     gene            847..1536
                     /locus_tag="IV356_001293"
     CDS             847..1536
                     /locus_tag="IV356_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP9014991.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1523..2731
                     /locus_tag="IV356_001294"
     CDS             1523..2731
                     /locus_tag="IV356_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP9014992.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            3025..4296
                     /gene="serS"
                     /locus_tag="IV356_001295"
     CDS             3025..4296
                     /gene="serS"
                     /locus_tag="IV356_001295"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HAP9014993.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4845..6329)
                     /gene="guaB"
                     /locus_tag="IV356_001296"
     CDS             complement(4845..6329)
                     /gene="guaB"
                     /locus_tag="IV356_001296"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HAP9014994.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6834..7529)
                     /locus_tag="IV356_001297"
     CDS             complement(6834..7529)
                     /locus_tag="IV356_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HAP9014995.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7619..8719)
                     /gene="ychF"
                     /locus_tag="IV356_001298"
     CDS             complement(7619..8719)
                     /gene="ychF"
                     /locus_tag="IV356_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HAP9014996.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8728..8919)
                     /locus_tag="IV356_001299"
     CDS             complement(8728..8919)
                     /locus_tag="IV356_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HAP9014997.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8940..9830)
                     /locus_tag="IV356_001300"
     CDS             complement(8940..9830)
                     /locus_tag="IV356_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HAP9014998.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9817..10584)
                     /locus_tag="IV356_001301"
     CDS             complement(9817..10584)
                     /locus_tag="IV356_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAP9014999.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10596..11309)
                     /gene="rsmG"
                     /locus_tag="IV356_001302"
     CDS             complement(10596..11309)
                     /gene="rsmG"
                     /locus_tag="IV356_001302"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HAP9015000.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11541..13442)
                     /gene="mnmG"
                     /locus_tag="IV356_001303"
     CDS             complement(11541..13442)
                     /gene="mnmG"
                     /locus_tag="IV356_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HAP9015001.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13459..14856)
                     /gene="mnmE"
                     /locus_tag="IV356_001304"
     CDS             complement(13459..14856)
                     /gene="mnmE"
                     /locus_tag="IV356_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HAP9015002.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            15200..15538
                     /locus_tag="IV356_001305"
     CDS             15200..15538
                     /locus_tag="IV356_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015003.1"
                     /translation="MSPFRSAALEEESDPRINDVVLSTGNINQKYIVRDIVFVVECLE
                     ADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQKKRDGKYFLELFAYGT
                     VIQFIQTTIG"
     gene            complement(15706..16464)
                     /locus_tag="IV356_001306"
     CDS             complement(15706..16464)
                     /locus_tag="IV356_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAP9015004.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16482..17300)
                     /locus_tag="IV356_001307"
     CDS             complement(16482..17300)
                     /locus_tag="IV356_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAP9015005.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17297..17653)
                     /gene="rnpA"
                     /locus_tag="IV356_001308"
     CDS             complement(17297..17653)
                     /gene="rnpA"
                     /locus_tag="IV356_001308"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HAP9015006.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17771..17905)
                     /gene="rpmH"
                     /locus_tag="IV356_001309"
     CDS             complement(17771..17905)
                     /gene="rpmH"
                     /locus_tag="IV356_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HAP9015007.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18428..19762
                     /gene="dnaA"
                     /locus_tag="IV356_001310"
     CDS             18428..19762
                     /gene="dnaA"
                     /locus_tag="IV356_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HAP9015008.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19960..21090
                     /gene="dnaN"
                     /locus_tag="IV356_001311"
     CDS             19960..21090
                     /gene="dnaN"
                     /locus_tag="IV356_001311"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HAP9015009.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21319..21561
                     /gene="yaaA"
                     /locus_tag="IV356_001312"
     CDS             21319..21561
                     /gene="yaaA"
                     /locus_tag="IV356_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HAP9015010.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21548..22672
                     /gene="recF"
                     /locus_tag="IV356_001313"
     CDS             21548..22672
                     /gene="recF"
                     /locus_tag="IV356_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HAP9015011.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQTRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22669..24615
                     /gene="gyrB"
                     /locus_tag="IV356_001314"
     CDS             22669..24615
                     /gene="gyrB"
                     /locus_tag="IV356_001314"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HAP9015012.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24635..27106
                     /gene="gyrA"
                     /locus_tag="IV356_001315"
     CDS             24635..27106
                     /gene="gyrA"
                     /locus_tag="IV356_001315"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HAP9015013.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27342..27641
                     /locus_tag="IV356_001316"
     CDS             27342..27641
                     /locus_tag="IV356_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HAP9015014.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27691..28203
                     /gene="ssb"
                     /locus_tag="IV356_001317"
     CDS             27691..28203
                     /gene="ssb"
                     /locus_tag="IV356_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAP9015015.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            28229..28465
                     /gene="rpsR"
                     /locus_tag="IV356_001318"
     CDS             28229..28465
                     /gene="rpsR"
                     /locus_tag="IV356_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HAP9015016.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28608..30581
                     /locus_tag="IV356_001319"
     CDS             28608..30581
                     /locus_tag="IV356_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HAP9015017.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30587..31039
                     /gene="rplI"
                     /locus_tag="IV356_001320"
     CDS             30587..31039
                     /gene="rplI"
                     /locus_tag="IV356_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HAP9015018.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31313..32680
                     /gene="dnaB"
                     /locus_tag="IV356_001321"
     CDS             31313..32680
                     /gene="dnaB"
                     /locus_tag="IV356_001321"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HAP9015019.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33460..34752
                     /locus_tag="IV356_001322"
     CDS             33460..34752
                     /locus_tag="IV356_001322"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HAP9015020.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10613 a         6777 c         6893 g        10585 t
ORIGIN      
        1 tctttttccg gtggagcaag ctccggtgga aaaagaagcg ttcgacttgc atgtattagg
       61 cacgccgcca gcgttcgtcc tgagccagga tcaaactctc ataaaaagtt cgaacaatct
      121 tgcgattgtt aagctcaatt tgtttgctag catattgctt gcttgttaaa aatgtttgtt
      181 gtcttgaatt gaatcaagac gccctacaca tttggtttgt cttactttgt tcagttttca
      241 aaggtctact tcatcaggag tgtttcccga ttcgtttttg gctgccgtag caacttttat
      301 atcatatcag agagacaagt aattgtcaac tcttttttaa aagttttttc gatttcgttt
      361 ttcgaaatct tccagcaact catttatcat aacttatcgt ttgttatttg tcaagaactt
      421 ttttgaagtt tttttcgata gaatcaagct tcgcaagtgg ttctttttta acgactcagt
      481 tatcttatca tgtcatttcc aacatgtcaa caacttattt tttattattt aataagttat
      541 tggtgttctt ttgaacaaat aataatatat caacatcaca tgtgaaagtc aataagaaaa
      601 tgcttattta tcaacatttc tagcttacat gatcattggt tagttctggt cctttttcgt
      661 tcgtctttat aactccgaga gacgtaaaat ccttttgttt tcagtttaat gttcatgttc
      721 ttgtcttatt cacaccaact agatgtctca ccttctaaaa ttttccttaa caaagtgctg
      781 cttttatcta tttctgcttt tttttgctag aataatagta acaatatgac tctggaggat
      841 ttatttatga aaattttgat tgctgacgat gataaagaaa tcgttgaatt attaagtatc
      901 tatgttcaca atgaggggta tgaagcagta aaggcttatg atgggaaaga agcattatct
      961 aaaatcagaa caatccctga tattgaatta cttattttag atatcatgat gcctgagatg
     1021 gatgggatgc aagtagtgaa agagctacga aaagaatccc aaataccaat cattatgctg
     1081 acagcaaaaa ctactgatat ggataagatc aaaggactgg tcgctggtgc agatgattat
     1141 gtgaccaagc catttaatcc gttagaagta atggctagag taaagtcttt attacggcgt
     1201 acaaaaatgc agattgcccc agatcagcct gatgtattag aagtaaatgc attaatcatc
     1261 aataaagact ctcatgaagt taaaacaatc gatgggaaag aaatccagtt aacagctttg
     1321 gaattcggta tcctctactt gcttgctagt catcctaatc gagtatttag cgcggatgaa
     1381 atttttgagc gtgtttggaa acaagaaagt attgtctctg ctaaaactgt catggttcac
     1441 gttagtcatt taagagataa gattgaagaa gcaactggtg gtgaaaaagt cattcaaacc
     1501 gtttggggag tgggctataa aattgacgca agatagtaaa cgagcaactg aaaaacgccg
     1561 tcggatcaat ttgacttcaa aagaaatcag cgaattgtta gcggaaggaa tcatcacgat
     1621 tatccttttg cttctattaa atgtttctat tctggttgtt atcagttcgg tgatcaacag
     1681 ttcaccttct ttgacgaatg cgatttggga ttcaaagaat atttttgcag aacgattgaa
     1741 cactgatttg ttctggaacg gccggaattt tattattccc tttttctttc tattagatat
     1801 tggtgttttg tattggcgct tgattcgaag atatcgccaa atgcaattgc ggcatatcat
     1861 cagcgaactt cactacatcg caaacggaaa ttatgatcat cgtatccctt ttgaactgag
     1921 tggtgactta agccgagtgg taacaagtat caatggattg gtggatagta ccgtagcagc
     1981 gattgaagac gaacgtaaaa tcgaaaaatc aaaagatgaa ttgatcacga atgtcagtca
     2041 tgatatccgt accccactca cgtccatcat tggataccta ggactgatag aagatggcca
     2101 gtatcactca gaagaagatc ttttaaagta tacgcatact gcttatatca aagcaaagca
     2161 gatgaaatct ttagtggacg acttatttga atacactaag gtacgccagc ctgctgtccc
     2221 ggtgaatttt tctgcctttg acatgatcca gttgatcgaa cagttagcag ctgattttga
     2281 gttggaagct tctaaaaaaa atatccaaat acttgttcaa tcaaaagtag actcccttat
     2341 catggatggc gataccgaaa aacttgtacg tgtcttcaat aatcttttga cgaatgcgtt
     2401 gaaatacgga aaaggagcaa cgaagatcgt aatcgaagta gaacgtatcg gttcagaagt
     2461 tgttgcaaca gtcaaaaata acggagcaat gatcccacaa caggcaatcg ataatctatt
     2521 cgaccgtttt tatcgtgtag aagaatctcg ttcacaagca actggaggaa ctggacttgg
     2581 tttagcaatc gctcaaagca ttgtggcttt gcacggcgga tacatttatg caaaatcaga
     2641 taagcaatgg acttctttca tcatgcacct tccaatcaag aaaaatgaaa aattacctat
     2701 tgatacacag gaagttattg acgaaagctg aaatattcgc tattcttatt acaattatta
     2761 gaataaatga aaaacacaga acccagtaca ctttattctt tttcagagag ctgatggcag
     2821 gtgtaaatca gcaaaggata atttggaagt tccagttcgt ttacgtgccc tttcgaaata
     2881 agaaaggtcg gttcaacagc cgttatgtgt tcaacaagtg cagctgacgc tgaacttggg
     2941 tggtaccgcg aatttcagac tgattcgtcc caagaataat gggatggatc agtctttttt
     3001 tattttcaaa aaggaggaaa tcatatgtta gatgtaaaaa tgatgcgaca aaatattgaa
     3061 gaagtacaag aaaaattgat gactcggggc gtaaaaaaag aaacattagc tgaattcatg
     3121 gaactagatg aaaatcgtcg taagctacta gtcaaaagtg aagaattaaa aaaatatcga
     3181 aatgatgttt ctgctgagat cgcccaattg aagcgtgcaa aagaagatgc ttctgctaaa
     3241 atcgctgaaa tgaaagaagt cggtggcaac atcaaagcat tggatactga aattgctgaa
     3301 gtggatgaaa aattgaaaca aattgcaact actttgccaa accttcccca tgattctgtg
     3361 ccagttggaa cagatgaaga ggacaatgta gaaatccgtc gttggagcga accacgtaca
     3421 tttgcttttg aaccaaaacc acactgggaa attgcagaaa atcttgatat tttagatttt
     3481 gaacgtggcg caaaagtagc cggtagccgt tttgtctatt acaaaggatt aggtgctcga
     3541 ttagaacgtg ctgtctacaa cttcatgctt gatcagcata tttacgaaca cggctatact
     3601 gaaatgatca ctccttatat cgtcaacagt aaagcgatgt ttggtacggg acaatttcca
     3661 aaattcaaag aagatgtttt ccaattggag aatactgatc taacattaat cccaacagct
     3721 gaagtaccat taactaacta ttataatgat gaaattttag atggtgcaga tttacctatt
     3781 tatttcactg cactaagccc tgcttttcgt tctgaagccg gaagtgctgg tcgggataca
     3841 cgaggactga ttcgtcttca ccaattcaat aaagtagaaa tggtcaaatt ttcggatgta
     3901 gagcattctt acgaagaatt ggaaaaaatg acagctgatg cagaagatat cttgaaaaaa
     3961 ttgcatttgc cttatcgtgt gatggcctta tcaactggag acatgggctt ttctgcagct
     4021 aaaacttatg acttagaagt atggatacct gcacaagata cttatcgtga aatcagttct
     4081 tgttctaact gtgaagattt ccaagcacgc cgcgcaatga tccgttatcg cgataatgat
     4141 ggaaaaatcc actatactca tactctgaat ggttcaggac ttgcagttgg ccgtacagta
     4201 gctgccattt tggaaaacta ccaaaatgaa gatggttctg tcacagttcc agaagcgctc
     4261 gttccttata tggggaatct gaaagttatt aaataaagag gctgtgaaaa agccgcttag
     4321 tttcgagtat taagaaaaat tttgtgaaaa tggctttcca catttttgca taaattggac
     4381 ttaataccga gaaactggct tttgaacacc atttatcgag aggttgtgaa atcagcgaat
     4441 taacctgagt attagagaaa aaaatggaaa aatagtccct catattttac cgtttgttga
     4501 actaataccg agggtcagct gattgaacac cgtttagtgg agaggtcgta agcctacccc
     4561 ccagctccta gttacaagga caaattcaaa aaacagctct tcatatttta tgaatgttgt
     4621 acttgtgatt cggaggtggc aagggaacac tgtttattca aaaagaggct gggacagaag
     4681 cgtttaactc caagaaataa gaagaaattc acgaaaattg cttttcaaat ttttgtgaat
     4741 ttcttcttat ttccgaagga gttgcttcta cttccgccgt ttatacgtgt ttagagcgtg
     4801 agacaaaagt gttctttact tttgtcccac gctctttaat gtttttaaga ttcaactgaa
     4861 tagtttggtg cttcttttgt gatttgtaca tcatgagggt gtgattcttt taatccactg
     4921 ccgctcattt ggataaattg cgcttcatca cgtaattgct gtagattggc tgccccaaca
     4981 taacccattc ctgaacgcaa accgccgatc atttggaaaa taatatctgc aacacttcct
     5041 ttataagcaa cccgaccttc gattccttct ggtactaatt tatttgcttc attgacacta
     5101 ccttggaagt aacggtcttt tgaacctttt tccatcgcgc ctaatgagcc catacctcgg
     5161 tatgttttga atcgacgtcc ttggaagatt tcgaattcac ctggtgattc atctgtccct
     5221 gccaacatac ttcctagcat cactgcatgt ccgccggcag ctaatgcttt gacgatgtca
     5281 ccagaatatt tgatccctcc gtctgcaata atcgctttgc catattgacg agcaactgat
     5341 gctgcatcat aaatagctgt gagctgaggt acacctacac cggctaccac acgtgtcgta
     5401 caaatcgatc ctggtccgat accaactttt acgacatcta cacctgcatc atataaagct
     5461 tttgtcgctt cagccgtcgc aacgtttcct gcaatcaatg ttgcatctgc aaaagttgaa
     5521 cggatttctt gaatttttcg gatcacacct gcactatgtc catgagctgt atcgatgatg
     5581 attgcatctg cccctgcttc taataaagca ttcgcacgct caaatgtatc gcttgttaca
     5641 ccaacggctg ctgctacaag caatcgacca tgttcatctt ttgctgcatt tggaaattcg
     5701 atcactttct cgatgtcttt gatcgtgatc aatccgctta aacgaccttc gttatctacg
     5761 attggtaatt tttcgatttt atgtttttgc aaaatctttt ctgcatcttt tagagaggta
     5821 cctactgggg cagtcactaa gttgtctttt gtcatcacat cagcaatcgg catgtgataa
     5881 tctgttacaa aacgcatgtc gcggtttgta attatcccta ccaattttct gttttcaagt
     5941 gtttcaacga ttggcacacc actgatacga tatttgctca tcaattcttc tgcgtctgct
     6001 acaagatgct gtggcgttaa gaagaacgga tcaatgatta cgccactttc agaacgtttg
     6061 acttttctta cttcatccgc ttgctggctg atcgtcatgt ttttatggat cacacctagt
     6121 ccgccttgtc ttgccatagc aatggccatc ttgctgtcgg taacagtatc catacttgca
     6181 ctgatgattg gaatattcaa cttaatattt ttagctaatt gtacgctcat atccacttcg
     6241 tttggtaaca cgtgactttc tgctggtatc aataagacat catcaaaagt aaatcctttt
     6301 ttcgtgaact ttgtttccca gttggacatt tttagtacca ctcctctaat ttagtttatc
     6361 tattaaaata attgattttt tcatttaagt caatgatcta cttggaatca agttagcttt
     6421 ctcatagaat accaatataa agcgtttaca tctgtgtata ttaaaagaga ttgtaaaaaa
     6481 gctgtcctgc atcaagtaat aagaacagcc aatcaaaaac agcttctcat gtttttgaat
     6541 tggttgggtt tattaccgca gatgcaaact tttgaacacc gtttagtgga gaggctgtga
     6601 aaaagctgct tagtttcgag tagtaagaaa aattttgtga aaatggcttt ccacattttt
     6661 gcataaattg gacttaatac cgagaaactg gcttttgaac accgtttatc gtaaaaaggg
     6721 actgtgacaa gacttttgtc acagtccctt actattattt aactatggat aaacaaaatg
     6781 aggttcttta ctacccctag atatctagca aaatagctga tctttttgct agtttatctt
     6841 cttgggacgg ataaacttcc aataatcccg tattttttct tcaagtagta acggattgct
     6901 aaagcagttg ccccgataat gataactact actggatcta atactggatt gataactggt
     6961 ggcaatagtg ttgtcgcaga aaacagtacg acccaaagaa gtgtcgttcc acctaggata
     7021 agcaatgtct tacccattcc tggtttcttg cttcgatctg ctccgggata ttcatattga
     7081 tagatgtatt tgtacatcat ataaaagacc cagccaccga ttgcagaacc tagaacgagt
     7141 gtagaaaagc cataagctgg cgttgttcca cgtgaaaaca atccggtaat cgcaatcatg
     7201 atacttaata gaccaagcaa cagcaacgta ttatctaacc acatcaataa aggggtggat
     7261 gaatttttta cttctgctgg cttattgatg attgcttccg ttctttcaga gactgtccca
     7321 aacaattgac gggctgttct tccgcctttt tgttctgcaa ctaaagtagg cagaatgtca
     7381 tgaagggctt ttactttttc ttcttcagac aaattcgctg cttctaaaga ttttttcaaa
     7441 tcaaaaatgt actgttgatt tcttttggtt aattttgttt ctaaactatt gttttctttt
     7501 acgattgctc gtaattgttc tggttccatt atctaatagt cctccttagc cgttcctttt
     7561 ctcaacggtc gtcacaaaag acattctacc atattctaca gctagtttga tagccctttt
     7621 acacattaaa gcggaataac attacgtcgc cgtcttgtac gacataatct tttccttcta
     7681 atcgaacacg tccagcttct tttgctgcat gcatgtttcc gtaatgatcc aagtcttcaa
     7741 aagagacagt ttctgcacgg ataaatccgc gttcgaaatc tgaatggatg attcctgctg
     7801 cttgtggtgc tttgattcct tttttgaatg tccaagcacg tacttcttgt tccccagcag
     7861 taaagtaagt agctaagcct aacaaatcat aagcagcacg gatcaactga tccaaacctg
     7921 attcttcgat tcctaaagct tctaaaaatt ccgctttgtc ttcttcatct aattctgcga
     7981 tttcttcttc tgcacgagca ctgaccacga tcacttctgc attttcttct gcagcaaagt
     8041 tgcgcacttc ttgtacataa tgattcgcgt ctgcatctgc tacgtcatct tctgagacat
     8101 tggctacata aagaattggt tttgtcgtca ataaaaatag tgatttaacg attttttgtt
     8161 cttcttcagt aaattcgatc gttcgggcag attttccttc ttccagtaca ggtttgattt
     8221 tatccagtac agctagttct gccactgcat ctttatcttt ggttttagca acttttgcta
     8281 cacgagtata gcgtttgttg atagattcta agtctgctaa cactagttcc aagttgatcg
     8341 tatcaatatc ttctagtgga tcaacacgtc cttctacgtg agtaatatta tcatcatcaa
     8401 aacagcgaac aacgtgacaa atagcgtcta cttggcggat atggcttaag aattgatttc
     8461 ccaaaccttc tcctttactt gcgcctttta cgattccagc aatatctgta aattcaaaag
     8521 tcgtcggaac agtttttttc ggatgtacaa gttctgttaa gcgttgcaaa cgccagtcag
     8581 gtacttctac catccctacg ttggggtcga tcgtcgcaaa gggatagttt gctgcttctg
     8641 ctcctgcttt tgtgatcgca ttaaacaaag ttgattttcc tacgttgggc aacccaacaa
     8701 ttccagcagt caatgccata aatttattca ctctttctct gcattttttt caattacttt
     8761 ttttaatttc ttttcaaaat ctcgacgggt catcatgacg atatgtccgc aattcataca
     8821 tctgattttg atatctgcgc ccattcgaat gacttcccag cgattcgtct ggcaagcgtg
     8881 aggttttttc atttcaacga tatcgtgcaa gtcgtacata aaaatagcct cctttttgtt
     8941 tattcttcat caaattgaat attcaagata tcaagaattc gagtcaaatc tttttgagaa
     9001 agatattcaa tctcgatctt acctttccca tttttttctt ggatagctac acttgtacca
     9061 aatttatcca tcaaacgatc ttcgctttct cggatataat atggtttttc ctttgctagc
     9121 cttgggattt ttttcttttc ttttccatca ttttgattta actcagaaac aagctgttcc
     9181 agttggcgga cagttaaatt ttcagttact gcacgattgg ctaatttcaa gatcaatgtt
     9241 ttatttttta aacctaacag cgtacgggct tgtcccatag ataaacgctg atcttgtacc
     9301 atttccttga caagatccgg taaagaaagc aagcgcaaat aattggcgat ataaggtctg
     9361 ctctttccta aacgactagc tacttctgct tgtgttagtt tcaggttttt catcagcatc
     9421 tcatatgctt ctgcttcttc taacggattc agatcttctc gctgcaagtt ttccagcact
     9481 gctacttgca tcatcgcttc ttcgtcaaag tctctaacga tagcagggat cgtttctttt
     9541 tcagctagtt tggacgctcg aaaacgtcgc tcccctgcaa taatctcata tccttttact
     9601 gcggaacggc gtacgatgat gggttgaaag acacctgatt gttcaataga attagctagt
     9661 tcctgcaaag atacttcttc aaatgtttta cggggctgat acggatttgg tcgcagctca
     9721 ttcaatggta gctggacaac ggtatcatct tttacatcca ccgtctctaa gttttctaaa
     9781 tcttgaaaca gtgcatcgat tcctcggcct aatcctttac ttttcttcac gacttaccac
     9841 ttcctttgcc aatgcttggt agacttcagc tcctcgagaa cgtggatcgt agtcgatgat
     9901 cggttttcca tgactaggtg cttctgataa acgaatattt cttggaatga tcgtttcgta
     9961 aactttttcg cggaagtatt tacgtacttc ttctacgact tcatttccca gatttgttcg
    10021 tgcatcatac attgtcagta agactccctc gatctctaat tctggattaa agtgtttttg
    10081 gactaaacga accgtattca gtaattggct taatccttcc aatgcgtaat actcacactg
    10141 aacaggtatc aaaatcgaat cacttgctgt aaatgaattg attgtcagat ggccaagaga
    10201 aggcgggcaa tcgatcaaaa tataatcata ctgactgctt acttctgcta aagatccttt
    10261 taatcttgat tctcttgcca tcattgacgt caattcgatc tctgctcctg ctaattggag
    10321 agtcgcaggc acaatactca aattttcgtg ttcagtgatc aaagttgcct catcaattgg
    10381 caattcattg actagaacat catagatgtc tcttgtcaca tcaggttttc tgatcccgac
    10441 accactggta gcatttcctt gtgcatccat atccactagc aatacttttt tgccaaggct
    10501 agcaagacaa gcacctagat tcaccgtcgt cgttgttttg ccgacgccac ctttttggtt
    10561 cgcaacagat attatttgtg ccatctcttc tcctcctatt tgattggctg cttattaggc
    10621 agtccgggct ttcttgggta tttctttggg gttggtttct ttttttgaat aacgatgata
    10681 tgccgttgat cagagacatt cggcaaggta accgcctctt ctttgaggaa tttaccacct
    10741 aataaagcaa tcgcttgttt tgcttctgtc aattcctctt cactttttgc tgctttcaat
    10801 gcataaaaat agccttcttg tttagccaag ggcaaacaca attccgctaa cacattcaaa
    10861 cgagcaaccg cacgagcagt gacaaggtca aatgatgcac gaaagtgagg attttgccca
    10921 aatgtttctg cccggtcatg atataaggaa gcatcgattc ctaataatcg ggttaactca
    10981 gataagaagg ttattcgttt attcagagaa tcaacgatcg ttatctgcag ttctggaaag
    11041 gcaattttta aaggtatgct aggaaaccct gcccccgaac caacatcgca taaagataaa
    11101 ggttgcgtaa agtctacttc aaatgctaat gtaagtgaat cgtaaaaatg cttcagatat
    11161 acgtcttttt catccgtaat agctgtaagg ttcatctttt cgttccattc gactaatgtc
    11221 cgataataaa tagcgaattg attcatttga tgatcggtaa gctctatccc tttttctgcc
    11281 aaggattggc gaaattcttc tggtatcata aatattcctt tcattgtgaa acagcaattg
    11341 tttcacagat tctctcccta ctttaacgca aaatctctag acatgcaatc cttccatatg
    11401 gattcttaaa aatttgaaaa gtaagaaaag ccgatagact ttttctttct agtatgactc
    11461 ataaaatata cacagaagag agaactagct ttgagcaatt tctgcaaaaa ctagttctct
    11521 cttctattta ttattacgta ttacgctggt tcactgactt tcgcaatctt cccttgttcg
    11581 atatagacca ttaggatact taggtctgca gggtttacgc cactgattcg gctagcttgg
    11641 gcaattgttt ctggttggat tttctgcaat ttttgttttg cttctgttgc taatccgttg
    11701 attgctgcgt agtcgatgtt ttctggaatc tttttcgctt ccatgcgttt taatttttct
    11761 actttttcca tggctttttt gatgtagcct tcatatttga tttggatttc tacttgttcg
    11821 atttcttttc gtgtcaattc ttcattttct ggaataaacc gtagaagttc tgcataagta
    11881 atctcaggac gtcttaaaaa gtcgcttgct agtacaccat cttttaatgg tgccgcatta
    11941 atcgttgcta aaaagtcttg gacttcttct gttggtttga ttcgtacatt catcaaacgt
    12001 ttgatttctt gttcaactgc ttcttttttc ttcaaataat tcttgtattg atcttctttt
    12061 actaagccta cacggtgacc catttctgtt aatcgcaaat ctgcattatc atgacgtaaa
    12121 agcagacggt attcagcacg tgaagtcagc aaacgataag gttcgttcgt tccttttgtt
    12181 accaaatcat cgatcatgac accgatgtaa ccgtcacttc gtttgatcac taaaggttct
    12241 tttccctgaa ctttcaaagc tgcattgata ccggcaatca gcccttgtcc agccgcttct
    12301 tcataaccgc ttgtaccatt tgtttgtcca gctgtataaa gattttcaac gactttagtt
    12361 tctaatgtcg gacggagctg gtgtggctct actacgtcat attcgatagc atatcctgta
    12421 cgcatcattt ctactttttc taatccagca atagaatgaa gcatgttgac ttgaacatcc
    12481 tctggtaaag aagtagataa accttgaaca tagacttctt ccgtatttaa gccttctggt
    12541 tccaaaaata attgatgacg tggtttgtct gcaaaacgca cgatcttatc ttcgatggat
    12601 ggacaatagc gagcgcctac cccttcaacg atccctgtaa acattggggc acgatgtaag
    12661 ttgtctcgaa taatttggtg agtcgtctca cctgtatagg tcagccagca agattcctga
    12721 tctagtttat aggcactatc tggtgtgctg aagctaaaat gattcggctc tttgtcacca
    12781 ggctgctctt ctgtaacaga atagtcgatc gtacttgatt ttactcgagg cggtgttcct
    12841 gttttgaacc gttcgatagc aaagccaagt tcttttagat gattcgctag tccaatagaa
    12901 ggttgagagt tattcggacc tgatgaatat ttcaattcac cgataatgat ttctccgcga
    12961 agtgctgttc cggctgtaat aacaactgct ttggcccggt agctcgctcc tgtggacgtc
    13021 actactccat gacaaacacc atcttcgacg atcagttctt cgacgattcc ttgtcttagc
    13081 gtcaaatttg gttctttttc gatcgtatgt ttcatttctg ttgaataagc atgtttgtct
    13141 gcttgtgctc gcaatgctcg gacagctggg ccttttcctg tgttcaacat acgcatttgg
    13201 atataggttt tatcgatatt cttacccatt tctccgccta acgcatcgat ttctcgaacg
    13261 acaacgcctt tagctggtcc gcctacagaa ggattacatg gcatgaatgc taccatgtcc
    13321 aaatttattg tcagtaataa tgtttttgat cccatacgtg cagcagcaag tgcagcttct
    13381 gaaccggcgt gtcctgcgcc aacaacgatc acgtcatacg catctgcttc ataatgttcc
    13441 aatcgtttgt tcctcctttt attttcctaa acaaaattga ctgaataatt gagtgattag
    13501 ctcatcttgt acactgtcgc cgacaacttc tcctagatag tcccagcaac gcgtcatatc
    13561 tatttgaacg agatccacag gcattcctga atcaatacct gcaatgactt cttcaagtga
    13621 gagggaagct ttttctaaca acgcgatatg gcgggtatta gaaacataag tagcgtctct
    13681 ttctcctgtt tctccgctga agaataaatc agaaatagct gattccaaac gatctagtcc
    13741 gtcgttttta gctacggaaa ttgaaaaaac tggttcattt tcgatcaatt tcttcaattt
    13801 ttcttgttcc agctgtgctg gcaaatctgt tttatttaga agaatgatcc gtttcaatcc
    13861 acttgtcgct tccaataatt gttcatcttc tgctgtcagt ggttcgcttt ggtttagaac
    13921 aagtaagatc aagtctgctt ctgctaatgc ttttcggctt ctttcgaccc cgatccgttc
    13981 caccacatct tctgtttccc gaattccagc tgtatcgatt agcttgagcg gtaccccccg
    14041 aacattgaca tactcttcga ttacatctcg agtcgttcct gcaatatccg taacgattgc
    14101 tttttcttct cttaacaaat ggtttaacaa acttgatttg ccgacatttg gccggccgat
    14161 gattgccgta cttaaccctt cccgcagaac cttcccttgc ttggatgtag caagtagcgc
    14221 ttggattctt tgttggatca tctgcgcttt ttcaagcaat aacttcgtag tcaattcttc
    14281 gacatcatca tattctggat aatcaatatt tacttctact tgtgctaatg tctctaaaat
    14341 ctcttgtctc aatgagcgga tcaaagcaga cagattgccg tctaactgat taagagctag
    14401 tcccattgct ttgtctgttt ttgcccgaat caaatccatc acagcttctg cctgtgaaag
    14461 gtcaacacga ccattcaaga atgctcgttt tgtgaattcg cctggctcag ctaatcttgc
    14521 accttctctt aacaatagct gcaaaatttg attgactaca acgatcccac cgtgacaatt
    14581 gatttctact acatcttccc gcgtaaatgt ctttggtgct ctcatcacgg agaccatgac
    14641 ttcatcgaca agctgattgc tcttgggatc aacgatatgt ccataatgga tcgtatgact
    14701 tggtacttct gataatcgtt tgtttccaga ttgataaact ttatctgcta gttgcacagc
    14761 ttgatcgcca cttaaacgaa cgatactgat tgcaccttct ccaggtgggg tagaaattgc
    14821 cgcaatcgta tcaaattcta aagtaatttc agccattttt tcacttcctt tttcattttg
    14881 cgcacaaaaa aagtgcccac tccacccttt atgcacaata aacggtgaac ttcgcacttt
    14941 gactgcttgt tcttgattaa attctggtca tagattatca cacttgctat aaggaatcaa
    15001 gtgtttaaaa caattagatg aagttgagcc tgttctgctt ccattacctt atatttaatt
    15061 gtccttggat gtctctttgc gttctttggt ttattcgaag agaagatact gtataaacaa
    15121 ggctttatct ttcttaaaaa aaacggtaca ctaaatggta gcgctatcta aactatacac
    15181 ttttgaaagg agaaaatatg tgagcccgtt cagatctgct gcattggaag aagaaagtga
    15241 ccctcggatc aacgatgtcg ttttatctac agggaatatc aaccagaaat atatcgtccg
    15301 cgatatcgtt tttgttgtgg aatgcttaga agctgatttg tttgacccat cttttcccaa
    15361 agatgacctt ttcttaacaa cgaagaggaa attaaagacg aaggtacttg aatatggtgc
    15421 gaatgcagta atcaactgtc attttgagta tcagcaaaaa aaacgcgacg gaaagtattt
    15481 tctggaactt tttgcttatg gaacagtgat ccaatttatc caaacaacga ttggttaaat
    15541 gaaacagaca aaaaaagcgg atcaaaactg aagacagttt cgatccgctt ttttctatca
    15601 aagttagtga ctacttcatc gtatactctg ataagaatga tttctagtaa aatatacttg
    15661 gtttgaaaaa ctttgtcaac gtgatttatt caaaaagtaa tggaatcaat aatatttttt
    15721 agcaggttct actactaaat aacgataagg ttcctcacct tccgaatgtg tttttacatg
    15781 ttcatctttg cttaatgcag catggatttg tttacgttca aatgcaggca ttggttctaa
    15841 gaaaacaggc tgccctgtcc gttttacttt ttcagccgtg cgatcagcta aacgctgaat
    15901 gatctcttgg cgcttttcac ggtaattgcc tacattgact actacagaca gcttatttct
    15961 tgctaaacga tggatgaaga cttgtgccag atattgcaat gcattcagtg tttttccatg
    16021 ttttccaatc agtatgcctt gcttttgtgt ttctaaatgg aaaacaacca tattatttga
    16081 ttctctttcc attttgacaa gagctggagc atcaagctgt tttgaaattt cagtaagata
    16141 aactgccaat tccgttaaag ctgcttcatc acctagctca cttacttctt ctgttttttc
    16201 ttcaagaatc gtttcgttga ctacctcgat ctcagctgtt ggttcttctt ccaaaatttc
    16261 ttctacagtc tgttctactg tttcagaaac tttttcgctg atacttggct ggatcgaaag
    16321 ccgtgcattc tttcgaccca ttcctaggaa accttttttt ccttcttcca gtatttcgat
    16381 ttcgacttgg tctttggcca aacccaaatc agccagacct agttggacag cttcgtctat
    16441 tgttgcagct tcataaatcg gcattagcat tacctcccct attatttccg ttttttctta
    16501 ggattcattg ctttcttaag agcacgttct ctttcgcgga ttctccgtgc ttcttcttca
    16561 cgctcttttc gaattttgaa agggttgttg atcagcagcg tttgtacaac ttggaaggca
    16621 ttggaaacta cccagtataa tgaaagaccg ctggctaaat tgacacccat cactaaaatc
    16681 attacaggca tcacgaaatt catgatcttc attgatgcat tcgattcaat ttgactcatg
    16741 ctagataaat acgtacttgc aaaagtaaag attgctgcta aaatcggcaa aataaatgtt
    16801 ggatccgcgt tccctaagtt caaccataag aaatgccctt gtttcaactc tggtacacgt
    16861 gaaatagatt gccataacgc catcaagatt ggcatttgta ctaataaagg aagacaacca
    16921 gcatatggat tgacgccatt ttctgcatat aaacgctgct gctcttctct taacttactt
    16981 tgtgtttccg gatctcttga actatattgt tgctgcagtg cttttaattt cggttgtaat
    17041 tcttgcgttt tacgcatgct ctttgtttgg aaatgcatca acggcaatag gatcacgcgg
    17101 atgatcagtg taaataaaat gatccctatc cctgcattac caaatgacaa cgccttgatc
    17161 gcctcagcaa agtaataaac aatataacga tcccaaattc ctgtactctg tgcgctgact
    17221 tccccagttc cgcaaccgga taagacgatg accaaactaa cgataccggc catcaaaagt
    17281 aaacgtttgt atttcttcac ttactctttt cctctctgtc gattattttt gcaagtttta
    17341 agacgtggac taaattggag cgaacctcat cataagtcaa ccccttcaca cttggtctag
    17401 caatcacaat aaaatccaac tccggatcaa tttcttcttt tatagaataa actgctgctc
    17461 ggatttttcg tttgacttca ttgcggttta ccgcgttgcc gacctttttt cctacagata
    17521 aaccaactcg aaaatgaggc tgtcccggtt tttccaaacg gtaaacgacg aatttgcggt
    17581 tagcaaaaga atctcccgta tggaacacgg cttgaaactc tcgttctttt tttactcgat
    17641 acgcttttct cattagtttt ctttcctttt ctatctctca cttacgctca taatcatacc
    17701 ataattacga ttgtcctttc atcatttccc taaaaaagag tataaaaaaa accactgaaa
    17761 ccccagtggc ctaagctgaa agaacttttc ttcctttgcg acgacggcta gctaacacac
    17821 gacgtccatt tttagtactc atacgtttac ggaatccgtg aactttttga cgtttacgtt
    17881 tatttggttg gtatgttctt ttcatatatt ccacctccaa aatgttctta tctattttat
    17941 aaacacagac atactttgat agtataacga caaagtagtg attttgtcaa tataaaatag
    18001 aagatcgatt gttaaaactt atccacaaga ttattttttt ctatgggaat cctatgtgga
    18061 aaaagttatg cacagggatt atccacagat aataaaaggc tggttttaca cagaaaacac
    18121 acgtgtaaaa aaagtaatcc acaatcaggc gatttcctgt gtattccgtc tcctaactat
    18181 tggtatatct gtatttttta tccacagacg caagaggaaa tctattggtt tttacgagtt
    18241 ttccacctgt gcattagtgg tgtggaaaac tttttttgac aactgtgttt ttctcttttt
    18301 tctttttgtc gattgtgtgg ataattgtaa ttaaaaaatt tttttcttcg gtttctgtgg
    18361 aaaactattg aaaaaaatgc taaattagta ctagttattc actttttaat gaaggaggag
    18421 gccttatatg gtatccctcg atgctttatg gaatgaatta aaagcaacat accaaaagga
    18481 tttatcgcct gctagctata atacatggat cgaaacagcg aaccctcgaa cccttgatca
    18541 aaaccagctc gttgttgagg ttcctagcaa gattcataaa gaatattggg aaaaaaacct
    18601 ggcgacaaaa atcgttgaag tcggttatat gttatcagga aatgagatta tccctcgctt
    18661 tattactggc gaagaagcag agcaagaaga agttatagaa gaaaaaaatc caaaagttgt
    18721 ggcacctagt ccgctaaaaa aagccatgct gaaccctaaa tatacctttg atacgtttgt
    18781 cattggtaaa ggaaaccaga tggctcatgc agcagcgctc gttgtagcag aagatccagg
    18841 ttctatttat aacccgctct tcttttatgg aggcgtggga cttggtaaga ctcacttgat
    18901 gcatgcaatt ggtcatcaaa tgctgcaaag tcagcctaat gccaaagtaa aatatgtaag
    18961 cagtgaaact tttgctaatg atttcatcaa ttcgatccaa aacaaaacag cagaagagtt
    19021 ccgtcaagaa tatcgaaatg ttgatttact gctagtggat gacattcaat tttttgcaga
    19081 aaaagaagct acgcaagaag agtttttcca tactttcaat gccttgtaca atgaagggaa
    19141 acaaatcgta ctaaccagtg atcggttgcc aaacgagatt ccgaaactgc aagaacgcct
    19201 tgtttctcgc tttgcatggg ggctgtctgt tgatattaca ccgccggatc ttgaaacaag
    19261 aacagcgatt ttacgtaaaa aagcggcggc tgaacgtcta gagatcccag atgacacact
    19321 aagctacatc gcaggacaaa ttgattctaa cattcgtgaa ttagaaggtg cgcttgttcg
    19381 agtgcaagct tttgctgcga tgaatagtga agatatttcg actagtctag ctgcagacgc
    19441 actgaaaacg ttaaaatcag gaaaaggaca tcctcaattg tcaatcctgc agatccaaga
    19501 agaagtggca aagtattatc acatccaatt gaaagatctc aaaggaaaga aacgcgtcaa
    19561 atctattgtt gttcctagac aaatcgctat gtatttggca cgtgagctca cagataattc
    19621 tttaccgaaa atcggagctg aattcggtgg caaggatcat acaacggtta tccatgctca
    19681 tgaaaaaatc cagcagctga tggattctag tgtcagtatg caaaatgaag tatcagaaat
    19741 caaaaacttt ttactaaatt aatttgtcga ttctatcaac tgaaaatagc atgtggataa
    19801 aagaaaaaaa cgttcaaaag ttatacacac tttttccaca gctgtttttt cgtttctctc
    19861 ttacgttttt tgagttttcc acagaatcaa catgccctat tacttttatt attcttttta
    19921 actaataata aataaacaaa cattcaaagg agatacatca tgaaagttac tttaaaccga
    19981 gctagcttta tgcaggaatt gcaaactgtt caacgagcta tttcaagcaa aaccacgatc
    20041 cctattttga caggtgtaaa aatcacactg acacaagaag gtttgacttt gacggggagc
    20101 aacgctgata tatcaattga aacttttttg tctgttgaaa acgaaaaagc aaatatgcaa
    20161 atcgaatcta ctggttccat tgttttacaa gcacgtttct ttagcgaaat cattcggaga
    20221 cttcctgaag aaacatttac tttagaagtt ttagaaaata aacaagtagc gatcacttct
    20281 ggaaaagcga attttatcgt aaatggatta gatgcagata actatcctca tcttcctgtt
    20341 gtcgaaagcc ataaccagat gaaattacct gtacacgtat tgactaaact aatcaacgaa
    20401 acagtttttg ctgtctcaca acatgagagt cgtccaatct tgacaggtgt gcatttcatt
    20461 ttatctgata attctttatt agctgtagct actgattctc accgtctaag tcaacgcgtg
    20521 attccagtag aacaagcggc tgatcatttt gatattgtta ttcctggaaa aagtttgatc
    20581 gaattatctc gctcattaac aaatgaagaa gaaatcgtcg aaatcagcat tatggaaaac
    20641 caagtgttgt tcaaaacaga aacgatgtat ttctattccc gtttgctaga aggaaactat
    20701 ccagatacca atcgtttgat tccttcaagt tttaatacag aggttgaatt ttctgttcct
    20761 agctttttag cggcgatcga acgggcttct ttactttctc atgaaggccg taacaacatc
    20821 gttcgtttat ctattcgtcc agatgcggtt gttttatacg gaaattcgcc agaaatcggg
    20881 aaagtagaag aaagcttgag ttatacagca agcagtggcg atccattaga tatttctttc
    20941 aatccggatt atatgaaagc agcgttgcgt gcatttggag atatgagcat caaagtgaaa
    21001 tttatctctg ctattcgtcc atttacattg gaaccaacgg aagatggcgt tcaatttatt
    21061 cagctgatta ctcctgtacg tacaaattaa caatgatttt caatgttctt gaaaatttaa
    21121 ttgaaaagaa atagaaaaaa taaaatttta aacagaaggc cctaaaatct cttttaaggc
    21181 tttctgttta tttttgttta aatcaccttt tttagattaa atcgtcttat atggaaaaat
    21241 atatggataa atttgtttta ttgcgaaaaa aaaggtataa tagagtatac ttttaataat
    21301 gaaaatgagg gatgggcatt gaaacaacaa gtcattctaa atacggaatt catgacgttg
    21361 ggccaaatgt tgaaagaagt cacagttatc ggtagtggcg gacaagcaaa atggtatttg
    21421 gcagaaaaca ctgtgttagt cgatggcgaa ccagaaaatc gtcgtggacg caaactttat
    21481 cccggcatga tggttgaagt tccagaagta ggaacttttt ttatggtaaa aaaaggaaac
    21541 gacgataatg aggctgaata agctgtattt aaaaaattat cgaaattacg aagagctgaa
    21601 catcgaattt tccaagaacc tcgtcatctt tttaggagaa aatgcgcaag gaaaaacgaa
    21661 tcttttggaa agtatctacg tattagctat gacgcgaagt catcggacaa gtagtgagca
    21721 ggaattgatt ggctggactg acgatcaggc gatgattcaa ggagagatca caaaaggttc
    21781 atccactctt ccattagaaa tcttattatc taaaaaaggc cgaaaaacca agatcaacca
    21841 tatcgaacag aaaaagttaa gtacttacgt gggacaaatg aatgtcattt tatttgcacc
    21901 agaagatctt tctttagtaa aaggcagccc gcagaccagg cggaagtttt tagatatgga
    21961 attaggccag atcaatccaa tctatcttta tgatcttgtc caataccaag caattttgaa
    22021 acaaagaaac cagtacttga agcaattgaa tgaaaaaaaa caaactgatt tgctttattt
    22081 ggatattttg tccgaacaac tagcagcgtt tggcagcaaa gtattgaaag caagagcaca
    22141 gttcgtcaag cgattggagt tttgggctaa ttctttgcat cagcaaatca cccatcaaaa
    22201 agagcagctg gaaatcgagt atctcaccgc agtcgattct ttagaaacac atacgcaaga
    22261 gcaaatccaa gaacaatttc tcgcactttt gaaccaaaat aaaaagaaag acctttttcg
    22321 gggaacaacg acagttggtc ctcatcgtga cgatctttcc ttttttatta atcagaaaaa
    22381 tgtgcagact tatggatcgc aaggacagca aagaacaact gcactaagtg tcaaattagc
    22441 agaaatcgat ttgattaaag aagagacagg ggaatatcca atccttttgt tagatgatgt
    22501 gatgagcgag ctggatgata atcgtcaact ccatctgcta gaaacaatcg aaggaaaagt
    22561 tcaaacgttc ttaacaacaa cgacacttga ccatgtaaaa aataaaatga ctgttgaacc
    22621 tgagattttt tatgttcaac aagggaaact aaaaggagaa gaaactgaat gacagaagaa
    22681 agaagtttag tagaacgcgc taaagagtat gatgccagtc agattcaagt acttgaagga
    22741 cttgaagccg ttcgtaaacg acctggcatg tatatcggtt cgactagttc tgagggtctg
    22801 catcaccttg tttgggaaat tgtcgataat tcgatcgatg aagtattagc aggttttgca
    22861 acgaaaatcc atgtgattat tgaaaaagac aacagtatca ccgttattga cgacggtcgg
    22921 gggatacctg tagatatcca ggcaaaaact ggacgtcctg cagttgaaac ggtctttact
    22981 gttttacatg ctggaggaaa attcggcggt ggtgggtaca aagtttctgg tggacttcac
    23041 ggagtaggat cttctgttgt taacgcgctt tctacacagc ttgatgtcaa agtatacaaa
    23101 gaaggaaatg tgtactatca agaatatcgt cgtggagctg tagtggacga cttaaagatt
    23161 atcgaacaaa cggatcgcca tggaacaacg gttcacttta cgccagaccc tgaaattttt
    23221 acagagacaa ctgagtttga tttttcaaaa ttggctaccc ggatccgtga acttgctttc
    23281 ttgaaccgcg ggatgcgtat atcgattgaa gacaaacgag aagaagaacc agtcatcaat
    23341 gaataccatt atgacggcgg gattaaaagt tatgtcgaat acttgaatgc aaacaaaacc
    23401 gtgatttttc cagaacctgt atatttggaa ggtgaacagc aagatatcgc agttgaagtc
    23461 tctatgcaat atacagacgg ctaccattcc aatatcatga gttttgccaa caatatccat
    23521 acgtatgaag gcggaacaca tgaatcagga ttcaagactg ctttaactcg tgtgataaat
    23581 gattatgccc gaaaacaaaa gctgatgaaa gaaaatgacg acaacttgac cggtgaagac
    23641 gtgcgagaag gattgacagc tgttatttct atcaagcatc ctgaccctca attcgaagga
    23701 caaacaaaaa caaaattggg caattccgaa gtacggacag tcactgatcg gttatttagc
    23761 gaacatttca tgaaattctt gctggaaaac ccaagtgtgg gccgtcaaat tgttgaaaaa
    23821 ggattactag cttccagagc tcgtctagca gcgaaacgtg cgcgtgaagt aacgagacgt
    23881 aaaggtgctt tagagattag taatctgcca ggaaaattag cggactgctc tagcaacgat
    23941 cctgaaaaat gcgaattgtt catcgtcgaa ggagattcgg ccggcggatc agctaagcaa
    24001 ggtcgtaatc gagagtttca agccatcttg cctattcgtg ggaaaatctt gaatgttgaa
    24061 aaagcaagca tggacaagat cttggcaaat gaagagatcc ggtctttatt tactgctatg
    24121 ggtacagggt ttggagaaga ttttgatgta tcgaaagctc gctaccacaa attagttatc
    24181 atgactgatg ccgatgtcga cggcgcgcat atccgtacat tgctgctgac tcttttttat
    24241 cgttacatgc gtcctattgt tgaagctgga tacgtctata ttgctcagcc acctttatac
    24301 ggggtaaaac aagggaagaa tattacgtat gtacaaccag gaaaaaatgc agaagaagag
    24361 ttgaaacaag tcgttgcttc acttcctgcc tcaccaaaac caagcgttca gcgttataaa
    24421 ggacttggag aaatggatga tcatcaacta tgggaaacaa ctatggaccc aagcaatcgg
    24481 atgatggccc gcgtcagtgt ggacgatgct attgcagcag atcagatatt tgaaatgttg
    24541 atgggggatc gagtagaacc ccgtcgtgca ttcatcgagg aaaatgcaca ctatgtgaag
    24601 aacttagata tttaatcatg aaggaggaaa aagaatgagt gaagaaatca gagaaaacat
    24661 ccatgatgtc aatctaacca gcgaaatgaa agactccttc atcgattatg cgatgagtgt
    24721 tattgtcgca cgtgcacttc ctgatgtcag agatggtctg aaacccgttc atcgccgtat
    24781 tttatacggc atgaacgaat taggtgtaac accggataaa gcccataaaa aatctgccag
    24841 aatcgtcgga gatgtcatgg gtaaatacca tcctcatgga gactatgcga tctatgagtc
    24901 aatggtacgg atggcacagc cattcagcta ccgttatatg ctagtggatg gtcatggaaa
    24961 ctttggttct gttgacggtg acggtgccgc cgctatgcgt tataccgaag cacggatgag
    25021 caaaatcgct acagaaatgc tgcgtgatat caataagaac actgttgatt tccaaagcaa
    25081 ctatgatgat acagaaaaag aaccagttgt actacctgct cgcttcccga atcttttagt
    25141 gaacggaaca acggggatcg ccgtaggtat ggccacgaat atcccacctc ataacttgtc
    25201 tgaggtagta gcggctatcg atttgctgat ggataatcct gatgtgacga ccaatgaatt
    25261 gatggaagta ttacctggac cagattttcc aacaggtggt ttggttatgg gaaaatcagg
    25321 aatccgaaga gcgtatgaaa caggtaaggg ttctattacc gtacgtgcaa aagttgagat
    25381 tactgagatg ccaaatggta aagaacggat catcgtgaca gaattgcctt atatggtcaa
    25441 taaagcaaaa ttgatcgaac ggatttctga actgcacaga gacaagcgta tcgaagggat
    25501 cacagatttg cgggacgaat cttcccgtga aggtatgcgg atcgtcattg acatccgtcg
    25561 tgacgccagc gcatctgtta tcttgaataa cttatataaa ttgacatcct tgcaaaattc
    25621 atttggattc aatatgttgg cgatcgaaaa aggtgtgccg aaagttttga gcttgaaaca
    25681 aattcttgaa aactatatcg aacatcagcg cgaagtcatc acaagacgga cagtctttga
    25741 aaaagaaaaa gcagaagcaa gggcacacat tttagaaggt ttgcgtattg ctttggatca
    25801 tatcgatgaa atcattgcga ttatccgcgg gtctaaatca gatgacgaag caaaagcgac
    25861 gatgatcgaa cggttcgatt tatccgatcg ccagtctcaa gctattttag atatgcgttt
    25921 acgccgattg accggtttgg aacgggaaaa aatcgaaaat gaataccaag aactcttaaa
    25981 actgattgaa gatttaactg acattctggc aagaccagaa cgtgttacag aaatcatcaa
    26041 gaatgaatta gcagacttga atcaacgatt tggtgataaa cgacgcacag aattactagt
    26101 cggtgaggtc ttaagtctgg aagatgaaga tttaatcgaa gaagaagaaa tcgttattac
    26161 attgacaaac aatggttaca tcaaacgttt ggcaaataat gaattcagag ctcaacgaag
    26221 gggtggacgt ggtgtccaag gaatgggtat ccacaatgac gacttcgtca aaaatctggt
    26281 ttcttgttct acccatgata cattgttatt ctttacgaat aacggaaaag tgtatcgggc
    26341 aaaaggatac gaaattccag aatacgggcg cacagccaaa ggaataccaa ttatcaattt
    26401 actaggtatc gattcgagtg aaagcatcca ggcaatcatt gcggtgacgg gagaagcaga
    26461 agaaggccac tatctcttct ttacgacgcg tcaaggtaca gtaaaacgta cttctgtcac
    26521 tgcttttgct aacatccgaa gtaatggtct gatcgcaatt ggtttgaaag aagacgatga
    26581 gctcgtcaat gtgctactga cagatggtca atctaatatc attattggaa cacataacgg
    26641 ctactctgtc actttcaaag aagaagcagt ccgcgatatg ggacgtacag cttccggggt
    26701 tagaggaata cgcctgcgtg aggaagatta tgtcgttggg gcagccttaa tgaaggaaga
    26761 tcaagaagta ttagtgatca cagaaaaagg ttacggaaaa cggacaaaag tatcggaata
    26821 tccagtgaaa ggccgcggag gtaaagggat caaaacggcg aacatcactg aaaaaaatgg
    26881 tccactagct ggattgacca ctgtttctgg agatgaagac atcatgctga ttacagataa
    26941 aggtgtcatt atccgtttca acgtatcgac tgtttctcaa actggacgtt caacattagg
    27001 cgtacgtttg atgaagatgg aagctgatac gaaagttgtc acgatggcag cagtcgaacc
    27061 agaagctgca gaacaaacag ttgaagaaca aggatcagaa gaatagccat caagactaat
    27121 tgtgtaagct agcaagaatg accgattaaa aaatctggtt attcctgctg gcttttttga
    27181 ttagttgaat ttctcttaaa atattcgaaa ctgttcattc tgtattgctt ttgaccaaaa
    27241 tagagtgtat aatcagagct tgtgagtagt ctaattaatt agataactct ccttgctctt
    27301 aggaacctaa gagccgaaag tccacaggga ggtgaatatc aatggaaaac acgaaatatg
    27361 aaatcatgta cattattcgt ccaaacattg atgaagaagc aaaaactgct ttaatcgaac
    27421 gtttcgatgc aatcttgaaa gataacggag cagaagttat cgaatcaaaa gattgggaaa
    27481 aacgccgttt cgcttatgaa atgaacggtt accgtgaagg tatctatcac atcgttaaag
    27541 tatcttctcc atcatcagca aatgctgtca atgaatttga ccgtcttgct aaaatcaacg
    27601 acgatatcat tcgtcacatg attgttaaag aagaagctta attgttgttt catgtgaaac
    27661 aatagaaaac gatgagagga gatgactatt ttgattaata atgttgtatt agttggacgt
    27721 ctgacgaaag atccagattt gcgttacaca gcaagtggta cggcagtcgc aacatttact
    27781 ttggctgtga atcgtaattt tacaaaccaa agcggcaatc gcgaggctga ttttatcaac
    27841 tgtgtgattt ggcgcaaatc agcagaaact ttagcaaact atgctcgtaa aggaacactt
    27901 ttaggtgtta ctggacgtat ccaaactcgt tcttatgata atcagcaagg acaacgtgta
    27961 tacgtgacag aagtagtagc tgacaacttc caattgctgg aaagtcgttc tgcatctgaa
    28021 aatcgccaac aaagcggcgg attccaaagt tctggtcaat cagctggcgg atttggcgga
    28081 aacaataact ctaatcaaac atctcaatca tccaacggta tgcctgattt cgaccgtgat
    28141 acttctgacc cattcggctc aagttcaacg atcgacattt cagacgatga tttaccattc
    28201 taaacgaatt tgataggagg gaaatagaat ggcacaacaa agaagaggcg gacgtaaacg
    28261 tcgtaaagta gactacattg ctgctaacca tattgaatat atcgattata aagatatcga
    28321 attactaaaa agatttattt cagaacgcgg taaaatcttg ccacgtcgtg taactggtac
    28381 aggcgctaaa aaccaacgta aaattactgt tgcaatcaaa cgcgctcgta tcatgggctt
    28441 gctacctttc gttagcgaag actaataaat cctaggaatt gaatgactga tccttttgat
    28501 cagctattca attccttttt ttctgtaaaa ataacctcta ttcgtttagt cgctcgaatg
    28561 acgaaagtta tggtaaaatc aaattagtca tatatgggag gaaaattatg gaaaataaaa
    28621 acaatcattt atccccgaaa cctctcttcc ttatcctgtt tatattaatc gaagtattgg
    28681 tagtcttaat tttaccattt cgttttgtta gcgcttcggt cattctattg atgaatttat
    28741 ggggtgttcg ctattggttg aaaatgaaac gttggcttat tttaaataaa cgtgaaaaaa
    28801 tccagcaggc ttcgactgta gctgaaacca atctagctta tgtctcagaa gtcatgcctg
    28861 taggagtgat tgcttatcag ccatcaagcc aaaaaatcga atggctcaat ccattagcat
    28921 tgaaaatcaa agatcaaagt ggattaacag aggaagaatt gctagatact ttttttactg
    28981 caaaagaaaa aaagaaaaac caagtctatc tagcagataa aacatttcag tttgatatgg
    29041 atacagtaaa gggtgttgtt tattttaatg atattaccca aaaccagttg ttaaaactcc
    29101 atcagacgaa cagtcagccg gtgattggta ttttatctat tgataactat gcagatgcca
    29161 ttgataaatt ggatgacaaa gagatttctt atttgaactc tttcgtcact acactagttt
    29221 ctgactggat gaatgaatac catgtctttt tcaaaagaat caacgcagaa cggtttttct
    29281 tcgtagcaca gatgatcgat ctgaaaaaga tgatggataa aaaatttgat ttgctggatc
    29341 gctttcgagc agaagctgaa aaacagagct cgcctatcac ccttagtatg gggattgctt
    29401 atggctcaag aaccctcgat gaaatcggtg gagaagctca gaataattta gatgttgctt
    29461 tagtccgtgg aggcgaccaa gttgtcgtga aagaggtaaa agaaggagca aaacctgttt
    29521 attatggggg gaaatctgct aagaatgtca aacgcacgcg tgttcgttct cgagcgatga
    29581 gtaccgcttt gcgtcggatt tttgatgaaa caggcgatgt gtttatcatg gggcacaagt
    29641 ttccggatat ggatgcttta ggctctgctt ttggtgtcag ttgtctggca cgcttcaacc
    29701 agaaaaaagc ttacatcgtt atcaacgaga acgagatcat tccagatgta gaacggtgtc
    29761 ttgaagaaat ccataagcat cctgaattag aaatgcaact aatctctcca gaacgtgcca
    29821 tagagctgaa aaaagaagag gacctcctcg tgatggtgga ttaccataaa ccttctctat
    29881 cgatctctca gggcctatat gagcaatttg ataagattgt gatcattgat caccatcgtc
    29941 gtggggaaga gtttccaagt aaacctctgc tgacttatat cgaatcttca gcttcttcag
    30001 cttcagagct agtttctgag ctgatccaat accaaagcag caaaacaaat cgcttagatc
    30061 gttttgaggc cacattattg cttgcaggga tggttgtaga tacaaatagt ttcaatgtcc
    30121 gtacaactgc acgaactttt gacgttgcca gctatttaag gtcttgtgga gcagacgcat
    30181 ccttagtaca atatttattg agctcggatt tagcgacata cttggagatc agcaatttga
    30241 ttgctggaag cgactatgtg acttctgata ttgttgtggc ggcagggaca gacgaaaaag
    30301 agtataatag tgttatagca gcaaaaacag cagatacatt gctttcgatg atcaatatca
    30361 atgcagcttt cgtcattaca aagcggacag acggcttgat tgggatcagt gccagaagta
    30421 ccggcacgat caacgtccaa atcatcatgg aatccttagg tggcggagga cacttcacaa
    30481 acgcagctac tcaactggaa aatacgacag ttgaggaaac aaaacagaag ctatttgctg
    30541 caatcaaaga aaatatgaat caaatatatg ataaggagta atccaaatga aagtaatttt
    30601 tttacaagat gtaaaaggaa aaggtaaaaa aggggacatc aaagaagttc cagcaggtta
    30661 tgcacaaaat tatctaatca aaaataactt ggcaaaagaa gcaacgaaaa gcagtatcag
    30721 tcagttagca ggacaaaaga aagcacaaga aaaacacgaa gctgaaatct tggaagaagc
    30781 taaaaagtta aaagaattct tggaaaaaga agatactgta gtcgaattga aggcgaaagc
    30841 aggggaagac agccgtttgt ttggttcgat cccttcaaaa caaattgctg aagggttaaa
    30901 caaacaatac aaaatcaaat tagataaacg aaaaatcgaa ttagaaaatc cgatccgttc
    30961 actaggctac acaaacgtac ctgttaagct tcatcatgag gtgacggcta cgatcaaagt
    31021 tcatgtcgta caagaataac aaatcttgat agcgatgttc agctggtaag tataaccaga
    31081 aggaaaaaag acaaaccgaa atttatctga gaaaacagct gcagcaatga aagcaaaagc
    31141 tgcaaatcga tttcagattg atttcggttt cttttttggg aacagcaaaa tagcataaag
    31201 aaaacgagta taataaaaga gaactatttt tttattacac tttcggtacg aatgatgact
    31261 tttctctcat tttcttgtaa aatgaagcaa ttgaagacaa ggagcgatac gtatgaatga
    31321 agtgtggcag gatcgaatcc caccgcaaaa tattgaagct gaacaagcgg ttttaggctc
    31381 tgtttttctt gacgcagaaa cgatcattga tgccatggag tacatagagc caaaagactt
    31441 ttatcgtcgt ggccatcaaa ttatttttga gacaatgatc gagttaaatg atcgtaatga
    31501 agcgattgac gtggttactg tcaaagaccg gctggaacaa gccaatttgt tagaagatgc
    31561 cggtggttta agttatctct cagacttggc attagcagtt ccgacagcag caaatatcgt
    31621 ctactatgcg aaaatcgttg aagaaaaatc attgctgcgt acattgatcc agacagcaac
    31681 aggaatcgtt acgaaaggat tcgagcaagg agaagaagtt caaacaattt tagatgatgc
    31741 cgaacgcagt atcttggagg tttcggaaaa aagaaatcga agcggctttt tatctattgc
    31801 tgaagtactg aactccacga ttgaaaatat cgatcgacta gctcaaaaca atgaagaaat
    31861 cacaggtcta ccaactggct atcaaggtct ggataaaatg acagcaggtt tccagcccga
    31921 agaactaatc attcttgctg cacgtccagc ggtaggtaaa acagcgtttg cattgaatat
    31981 tgctcaaaat gtaggaacaa aaacagatcg ttctgttgcg atatttagtt tggaaatggg
    32041 ggcagaatct cttgtaaatc ggatgctttg tgcagaaggt tcgattgagg ccagccattt
    32101 acgtacaggt cagctttcgg aagaagaatg gtcgaatctg atcgttgcga tggggagtct
    32161 ttctcgagca aatattttta tcgatgatac accagggatc aaaatctctg aaatccgtgc
    32221 gaaatgtcgg aaactagcgc aagaaaaagg caatctaggc ttgatattga tcgattattt
    32281 gcagttgatt gaaggtaacg gtaaagagaa ccgtcaacaa gaagtatcag atatctctcg
    32341 ccaactgaaa aaactggcga aagagctgaa agtacctgtc attgctcttt cacagttatc
    32401 tcgtggagta gaacagcgac aagacaaacg accagtgcta agtgatattc gtgaatccgg
    32461 atcaattgaa caagatgcgg acatcgtagc cttcttgtat cgagatgatt attatgaaag
    32521 agaaggcgga gatgacgatg atggaaacga gccaaaaaat gacaacgtca tcgaagtcat
    32581 catcgagaag aaccgaagcg gtgcacgagg aacagttgaa ctactgttta tcaaagaata
    32641 caataagttt tcgtcgcttt cgccaagaga agaattttaa agaagaggtt gtgagccttg
    32701 agcaatcccg agagctctcg taagaagatg caaggagtaa ccgcaggaac gactagagta
    32761 cttaatttaa acagatctcc aaagggattg tgacaaaagt cttgtcacag tccctttttc
    32821 cgaataaacg gtgttcaatc agctgaccct tggtattagc tcagcaaacg tcaaaatatg
    32881 aggaactatt ttgacgtttg tttctctaat actcaggtca aaacgctgat cttacgacct
    32941 cttttcctta aacggtgttc tcctgccaac tcctcggtca caagtcacaa tatcatcaaa
    33001 catgagaagc agttttttga aattgctcct tgtgactcag agttaaacgg caggctcaca
    33061 acctctttct taaacggtgt tcaaaagctt gcatctgcgg taatacgccc aatcaaacga
    33121 aaaatatgag aagctatttt tgtttggctg ttcttattac ttgatgcagg acagcttttt
    33181 cacaacctct gattcacggt gttccaaaag tagcttcttc gaaaaataag tcgaaatttc
    33241 acaaaaattt gagaagcaat tttcgtacat tccttcttat ttcttgaagc tgaccacttc
    33301 tgttacaacc tcttttttaa taaccattct aaaaagataa agttcgtttt ttaagcgttt
    33361 ttataaaata aaaataaaaa tcattcgatt ttatttgaaa tatgtatcta ttattgatac
    33421 aatggttcag gattaaataa tatagaacga ggtgttcaca tgtcatctgt agtagtagta
    33481 ggtacgcaat ggggcgatga agggaaagga aaaatcacag actttctcag tgaaaatgct
    33541 gaagtgattg cacggtacca aggtggcgac aatgcagggc acacaattaa gtttaacggt
    33601 gtgacttata aactgcattt gattccttct gggatttttt ataaagacaa gatcagtgtg
    33661 atcggaaacg gcgttgtagt caatcctaaa tcattggtta aagaattagc ttatttacat
    33721 gaaaaaggtg tagaaacaag taatttgcgt atttctgacc gcgcgcacgt aatcttgcct
    33781 tatcatatca aattggacca attacaagaa gatgctaagg gcgaaaataa gattggtaca
    33841 acgattaaag gaatcggacc tgcctatatg gataaagcag ctcgtgtagg tatccgtatt
    33901 gcagacttat tagataaaga aatttttgaa gaacgtcttc gtttgaatct agatgacaaa
    33961 aaccgtcaat ttgtaaaaat gtttgattca gaaccacttg attttgacga tatttttgaa
    34021 gaatattatg aatacggaca acaaatcaaa caatacgtca cagatacttc cgttatcttg
    34081 aatgatgctt tggatgcagg caaacgcgtg ttgtttgaag gcgcacaagg tgtaatgctg
    34141 gatatcgacc agggaactta tccttttgtt acttcttcta acccagtagc cggtggggta
    34201 acaatcggaa gcggtgtagg gccttcaaaa atcaataaag ttgtcggcgt ctgcaaagcc
    34261 tatacgtcac gtgtcggtga tggaccattt ccaactgaat tatttgatga aacaggagaa
    34321 caaatccgcg aagtaggacg agaatacggt acgacaactg gtcgtccgcg tcgtgtaggc
    34381 tggtttgatt ctgtagttat gcgccattct aaacgagttt caggtattac caacctatct
    34441 ttaaactcga tcgatgtatt aagtggattg gaaacagtaa aaatttgtac ggcttatgaa
    34501 ttagatggcg aactaatcta ccactatcca gcaagcttga aagagttgaa ccgctgcaaa
    34561 ccaatctatg aagaattgcc aggctggtca gaagacatta caggatgcaa aacacttgca
    34621 gaactgccag aaaacgcacg taactatgta cgtcgtatct cagagcttgt tggtgtacgt
    34681 atctcaacat tttctgtcgg acctgataga acacaaacaa acatcttaga aagcgtctgg
    34741 gcgcaaatct aaggataaaa acgacgactg aatcaggacg ttcttaccag agcgagtcga
    34801 agtgtttatc tatacgataa taataacttg aacactgttt attcagaata agggactgtg
    34861 acaaaaac
//
LOCUS       DACDLM010000027        33638 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.027, whole genome shotgun sequence.
ACCESSION   DACDLM010000027 DACDLM010000000
VERSION     DACDLM010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33638
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.027"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(104..475)
                     /locus_tag="IV356_001323"
     CDS             complement(104..475)
                     /locus_tag="IV356_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAP9015021.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            690..875
                     /locus_tag="IV356_001324"
     CDS             690..875
                     /locus_tag="IV356_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015022.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(958..1146)
                     /locus_tag="IV356_001325"
     CDS             complement(958..1146)
                     /locus_tag="IV356_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015023.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(1170..1433)
                     /locus_tag="IV356_001326"
     CDS             complement(1170..1433)
                     /locus_tag="IV356_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015024.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            1591..1848
                     /locus_tag="IV356_001327"
     CDS             1591..1848
                     /locus_tag="IV356_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HAP9015025.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(1919..2110)
                     /locus_tag="IV356_001328"
     CDS             complement(1919..2110)
                     /locus_tag="IV356_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015026.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(2251..2571)
                     /locus_tag="IV356_001329"
     CDS             complement(2251..2571)
                     /locus_tag="IV356_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015027.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(2594..3028)
                     /locus_tag="IV356_001330"
     CDS             complement(2594..3028)
                     /locus_tag="IV356_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAP9015028.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            3363..4001
                     /locus_tag="IV356_001331"
     CDS             3363..4001
                     /locus_tag="IV356_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP9015029.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(4325..4408)
                     /locus_tag="IV356_001332"
     tRNA            complement(4325..4408)
                     /locus_tag="IV356_001332"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4372..4374),aa:Leu,seq:cag)
     gene            4936..5436
                     /locus_tag="IV356_001333"
     CDS             4936..5436
                     /locus_tag="IV356_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP9015030.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            complement(5626..5970)
                     /locus_tag="IV356_001334"
     CDS             complement(5626..5970)
                     /locus_tag="IV356_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HAP9015031.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(6124..7044)
                     /locus_tag="IV356_001335"
     CDS             complement(6124..7044)
                     /locus_tag="IV356_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP9015032.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            7231..7722
                     /locus_tag="IV356_001336"
     CDS             7231..7722
                     /locus_tag="IV356_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HAP9015033.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            complement(7746..10120)
                     /locus_tag="IV356_001337"
                     /pseudo
     CDS             complement(7746..10120)
                     /locus_tag="IV356_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
     gene            10446..11072
                     /locus_tag="IV356_001338"
     CDS             10446..11072
                     /locus_tag="IV356_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAP9015034.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            11095..11799
                     /locus_tag="IV356_001339"
     CDS             11095..11799
                     /locus_tag="IV356_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAP9015035.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            11991..12824
                     /locus_tag="IV356_001340"
     CDS             11991..12824
                     /locus_tag="IV356_001340"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HAP9015036.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            13021..14949
                     /locus_tag="IV356_001341"
     CDS             13021..14949
                     /locus_tag="IV356_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAP9015037.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFSESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            15087..15542
                     /locus_tag="IV356_001342"
     CDS             15087..15542
                     /locus_tag="IV356_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HAP9015038.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            16012..16281
                     /locus_tag="IV356_001343"
     CDS             16012..16281
                     /locus_tag="IV356_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015039.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            16681..16935
                     /locus_tag="IV356_001344"
     CDS             16681..16935
                     /locus_tag="IV356_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HAP9015040.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(17024..18070)
                     /gene="holA"
                     /locus_tag="IV356_001345"
     CDS             complement(17024..18070)
                     /gene="holA"
                     /locus_tag="IV356_001345"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HAP9015041.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(18108..20381)
                     /locus_tag="IV356_001346"
     CDS             complement(18108..20381)
                     /locus_tag="IV356_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HAP9015042.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            complement(20374..20913)
                     /locus_tag="IV356_001347"
     CDS             complement(20374..20913)
                     /locus_tag="IV356_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HAP9015043.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            complement(21049..21267)
                     /locus_tag="IV356_001348"
     CDS             complement(21049..21267)
                     /locus_tag="IV356_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HAP9015044.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            complement(21264..21509)
                     /locus_tag="IV356_001349"
     CDS             complement(21264..21509)
                     /locus_tag="IV356_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAP9015045.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            complement(21625..22353)
                     /locus_tag="IV356_001350"
     CDS             complement(21625..22353)
                     /locus_tag="IV356_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComEA"
                     /protein_id="HAP9015046.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            complement(22512..23555)
                     /locus_tag="IV356_001351"
     CDS             complement(22512..23555)
                     /locus_tag="IV356_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAP9015047.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            complement(23545..24036)
                     /gene="coaD"
                     /locus_tag="IV356_001352"
     CDS             complement(23545..24036)
                     /gene="coaD"
                     /locus_tag="IV356_001352"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HAP9015048.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKNL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            complement(24033..24593)
                     /gene="rsmD"
                     /locus_tag="IV356_001353"
     CDS             complement(24033..24593)
                     /gene="rsmD"
                     /locus_tag="IV356_001353"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HAP9015049.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            complement(24712..25050)
                     /locus_tag="IV356_001354"
     CDS             complement(24712..25050)
                     /locus_tag="IV356_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HAP9015050.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            complement(25034..25471)
                     /locus_tag="IV356_001355"
     CDS             complement(25034..25471)
                     /locus_tag="IV356_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAP9015051.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            complement(25461..26585)
                     /locus_tag="IV356_001356"
     CDS             complement(25461..26585)
                     /locus_tag="IV356_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015052.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            complement(26606..30034)
                     /locus_tag="IV356_001357"
     CDS             complement(26606..30034)
                     /locus_tag="IV356_001357"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HAP9015053.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            complement(30060..31223)
                     /locus_tag="IV356_001358"
     CDS             complement(30060..31223)
                     /locus_tag="IV356_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAP9015054.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            complement(31226..31528)
                     /locus_tag="IV356_001359"
     CDS             complement(31226..31528)
                     /locus_tag="IV356_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HAP9015055.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            complement(31642..33414)
                     /gene="recQ"
                     /locus_tag="IV356_001360"
     CDS             complement(31642..33414)
                     /gene="recQ"
                     /locus_tag="IV356_001360"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HAP9015056.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
BASE COUNT         9866 a         6806 c         5738 g        11228 t
ORIGIN      
        1 tttttgcagg gggattattg tattattttt actacttgta tttagtttac ataattaaat
       61 tatgaataat aaaatcgggc gtattcttaa tacaaaaact gatttaccca ataattgcta
      121 atgctttctc cggaactttt tctctaggaa cttcctcata cgtttctatg tgtgctcctt
      181 tattgctaat tttcaaataa tgattttctt ttaacacaga aagaccatta aattcaaccg
      241 ttcgttcttt cccattggca tcagcagctt tctgcacata ccttgctgta ccatattcat
      301 ttacttcctc tggtttttgt gtctttacat agacctctcc tttttcaact aatggattta
      361 gctgatcaag tataccaggg atttctccat aacttccttc agtataatat ttcagtccaa
      421 atagcaaaat accactaatc gccgccagtc caatcaaata tttaatcact ttcatctttc
      481 tacctccttg ttatatattc agtatatggg tcagttaaag aaattccatc cgtcccaagt
      541 tggagatttt tctcctactt tagaagcgag aatcgagtgt ttttttagta aaaatgatcg
      601 ttatttgata ttattgacgt gtggataaat cagtttttct cgttttgtcc atgtaaaaaa
      661 tcatgttgat agcaaaggat gtgttcaaaa tgaatcaaga agaattattt caaaaagtca
      721 aggaaatgat taagaacggc aatttcgatg gcgcaaaacg atttatcgaa gaacataaag
      781 aacaattagg accttataaa gagaaagccc aaaatctttt aaaagatgta aatatcgaca
      841 gtgtcaaaaa caaatttaaa aatctattca aataagtaaa actttcactt ttgtaaaatc
      901 aaaggaggac aatgctgctg catcgtcctc ctttggttct tttctgaata cttcatacta
      961 aaataaacgt gtcggatcgt aatgataagt cacattgccg ttcagtgagg cttttcccac
     1021 cacatattta cgattctcca acttcagcca cgcttctcga aaagccatta attcttctct
     1081 ttttacatca atcttttcga tttttccatc gatcaaatct tgaataagtt gttcatatgg
     1141 attcattttt ttcctccatc tgctgtcaat caataagttg taaaaatagg ttcatatgct
     1201 tttttggtat ctagatcttc tctgactttg actgtcgtat aaataatttt ttctactggg
     1261 atactataat aacttccttc accattattg aatcggtgaa cgtctttctt tgctaaaata
     1321 ccatttattt tattcgtcag tacacgttgt tcgacactgt tacttacaac atagtaaatc
     1381 acccgaatat tattgatcaa atgcaaatcg atttctaaca ctacatgatc catgaaaatc
     1441 ccactccttc tttcactttg attatagcaa gtttctcctc taatttcaaa atcgatacag
     1501 attttaccgg ataaatccac aaaactgctt gcgccatttc gcacaaagtg ttattttgta
     1561 tcatggactt tatttatcgg aggcaatagt atgatcgcga tcggtcaatt tgttttttat
     1621 attccttttt ttattatgat aagcattctt ttctattaca taaaatggac aaaaaagaag
     1681 ttttcagttt tactggcctc tttacctgct gtatatttta cttatcaaat tttttctttt
     1741 aggcattggg aaacaacgtc tgtattaata acacacatca tcgaattgac gctttcagta
     1801 atttttctta ttatttggat ctatttttta tataagaatc agaattgaat ccctcgcatg
     1861 tttaaaaaga aaacgattaa agatgcagca aatttctgcc gatctttaat cgttttttct
     1921 attctgttat accaaaaaaa tgtttgaatc ggtgaaggat cgttccttgt tttaattcta
     1981 taaattcttg tgcgatcggg tacttttctt ccaaattttc tttgttcttt tcgatcaggc
     2041 ttttcgcttc ttcatatttt ttatctgcac atagtgcttt tacttcctgt aatacttttc
     2101 ctgcttccat ttgcctcacc ctcttgccat tttattgctt taagttttat ttaagttata
     2161 cgcattattc tagtttcatc ccaaataacc ttttttcatt tttactcctc gaactaatca
     2221 gttttctaaa ggctgattgg ttcgtctttt ttatttttcc tccatttcat tctgctcttc
     2281 tgttaattta tctaatgctt tgattgatgc tgcggctctt gcataatcat agctgtataa
     2341 ttccataaat ttatcaggca gaacaaacca cgctggatga taaccgttag ctgtgacagg
     2401 gaatccttta tcttgttggt tatctccatc ccatctcaga gcaacacctt tttttccttt
     2461 ccactttact aaagcgatcg agtatccctt ctttgtttgt gtgccgtctt caataattgc
     2521 taaaatttct attttttctt ttggcgcacg gacttcttga ggacgaacca ttttctattc
     2581 ctcccttatc tcattacttc acgaccaaca cactgcaagg ggcatgtgat acgacataag
     2641 aagcggtcga tccaactaat gcttgttgta tagcaccttt tcctgtcgct cccataacga
     2701 tcaaatcaat attttcttgt ccagggatga cattggcaat caaatttctt ggatctccag
     2761 tttcaactat tgcgtggatc tcagcaatgc cgtactcttt ggcatcattg atttttttca
     2821 gcatggctac ttctgttctt tgtttttcat ctgcatagat ttttgaaaag gcataggcac
     2881 tatgggtcag ctcaactttg ttgatgattg acacgataaa taagtgggct tcattgtcct
     2941 ttgctaagtc aagggcttca gcgaacgctt tgatcgattg tcttgatccg tcaactgcta
     3001 ccatgatgtt ctggtatctt ttactcattg gaaccgcctc ctttttcttt tattgtaaca
     3061 tctcaagcaa aaatacaaaa aatatacgca atatgtaaat aaaatgatga acaaaagcaa
     3121 tttctttcaa gttatttata catttctttt ctcatcagaa cacctgttct aatcccatta
     3181 tttctgcatt atgtgaaatt cctcatcatt tttcacatcg agcgaacatc attctgttac
     3241 aaaaaacgtg gatttgtcat aaattgtcat gcttctttta cctatgaaat attttcacgt
     3301 gttaaagtat tcctcgttga acacaacaaa taaaactttt taacgaataa aggagatttt
     3361 tcatgacatc acttaaaact ttactttttg gaacaacttt ggctgccggc gctgcattct
     3421 tcatgggaac gactgctcat gcggacgaag cttataccgt tcaatcaggt gatactctat
     3481 caacgatttc tcaaaaatac gttggtgata actccttgat caatgccatt gcagaatcaa
     3541 attcaatttc tgatattaac ctgatctact caggacaaca attaacaatc ccaacagaag
     3601 gctctgcaca agcagctgct gaacctcaag cagccgttca agaagcacca gtccaagctg
     3661 aacctgttca agctgaacaa cctgttgtac aagaaacggt tcaaacggaa acacaagcag
     3721 cgcctgttgc tgaaacacaa cctgctcctg ctgtaacaga aactgctgct actccagcaa
     3781 gtacaagctc tgcaaaagaa tggatcgcac aaaaagaatc aagcggttct tacacagcaa
     3841 cgaacggacg ttacatcggc cgttaccaat tagattcttc ttacttaaat ggtgactact
     3901 ctgctgcaaa ccaagaaaga gtagcagaac aatatgttac ttcacgttat ggttcttggg
     3961 aagcggcgaa agcattctgg gaagcaaacg gttggtacta agattcatta tttgaacgtt
     4021 taaacacatt caaaatatag taagaggtca tgcgatttat tctttcgcat gacctctttt
     4081 tgagtttaag tttagtcttt attccttaac tatcgtttgc cagtatttct tgtatcagaa
     4141 tctataaatc tactatttga atcaatctat taggttttaa actgtcccac cttcacacaa
     4201 attttttttg atttatttga atctggttcc gttgtttaaa atttttccta tattctttta
     4261 gataatatgt tattttcttt ctcatcgctc caggtgtacc ttctctttat aaaaaaacaa
     4321 attatgcggc taagaagact cgaacttcca cgaggtcacc ctcactagcg cctgaagcta
     4381 gcgcgtctgc caattccgcc atagccgcat cacatctttt agtttaggat tacatgtgtt
     4441 ttttgtcaag aacatatttt tgttcttttt catttctgta cgccctccct tatgccatct
     4501 acacaaataa ttcatccgag caactccatc atctattgag ggttggtgaa aaaatctgtt
     4561 ttatccatat gatcgatttc aatgttaaac gaacgactct gggattagta actattttat
     4621 ttttttcttc atttcttttt tcctcttttt ctcgattcag ctatcttctt tcatttggat
     4681 attgattatt tcttctgttg attactatcc ttctggaatt ctagacgctg aagtaattca
     4741 cgttttcttt cttctagaga tcataagtaa cgaatgaacg aacttcaaat aattttttta
     4801 ttgtaattca tatttgtatt gttcgatgat tcttaatacg atatgacaca ataaataaaa
     4861 ataggcatgg ctatttacaa caatagtgct atagtagaaa acaaatgaat aaggttactt
     4921 aaagaggtga atacgatgaa actgatcaaa ctatgggaag cagatttaaa gaaagcttat
     4981 cagctacaaa ctagctttgg accaaatgag agtggattta tcaacaatgc ttatggctat
     5041 acatttgctg aatttttaga ttatgtaaaa aaatgcgaaa aaacgtcttt aggaatcgat
     5101 cttcctgaga gttacgttcc cgcaaccgtc tttattttag aaagtgatga acatgagtat
     5161 gtaggaattt ttaatttgcg ccataaactg aacgaaacat taagaaacgg cgctggccat
     5221 attggttacg gcatctcccc taattatcgt aaaaaaggat atgccacaca aggattagca
     5281 ttagtactac aagaggcaaa aaaaatcggc attgatgagg cacttttgtc tgtaaataaa
     5341 aaaaatcttg gcagtcttaa agcacaacaa aaaaatgggg ctgcgattta tcgtgaagat
     5401 gagaaagaat actatacgaa aatcaaactg atgtaaaaaa gaaggattcc aaaaggaaag
     5461 ggatttgaat gtcctttatc aatagaacac atttatttaa ttaacttata atatagcaga
     5521 caaaatttta taaacaaaga aaccttttat ctcttttctt ctagaaagga taaaaggctt
     5581 ttttgttttt cctatttgct tctcatagct agtcagccaa gatttctatc gtatccccaa
     5641 cgcaatccgt gcataacggc tcatcttatc tgtcgtccat gctggatacc agactagttt
     5701 gacttctgct ttcgttactt ctggcacttc ttttaatgcg tcatggatag attctgttaa
     5761 aatatctgct aatggacagc ccatagttgt tagagtcatc ttaatgactg tttctccatt
     5821 ttcaggattg aattctatat cataaatcaa gcctaaattg acgatgtcga ttcctaattc
     5881 aggatcaatc accatttcca aggcagcaag aatacgttct ttgattagtt ctatttcttg
     5941 tccagaccgt tcttggtttg cttcgctcat cgtacgacac tccttaacac gatttttatt
     6001 tatcatactc tttttttagc tgcttgtaaa tgagaattta gaagtaagat tctcgtttaa
     6061 atttataaaa atgttcttat tagatgtaat agattaaatt tattctaaaa taaacctgat
     6121 tcctcatttt ttttgtgaac gattttttat ttctggcaat acgccagttg ttcgatacat
     6181 tttttgttcg ttttcatttg caaaccggcc aaatactgaa tgagttggta aaatattgat
     6241 aaatgcatcg tcgtcgattt catgaacgat ctgatcaaga tcatacattt cgtagcgggt
     6301 gatgaccatc atgatcatgt tcccttgttt ttttgaatag ccaccgacag acggcagtaa
     6361 tgtcattcca cgtaccatcc gttttgctag ttcttctgtt acctcttctg gcttgacggt
     6421 aacgatcatt gctgttactt tttgatgact cgtgtggatg gcatcaatta cttgagtcat
     6481 tgcataaatg gaaataatcg tatacaaggc actttcccag ttaaagaaga agcctgcgat
     6541 gactacaatg ataccattta gaatcagcat gtagtttccg actgtttttc cagttgtttg
     6601 tgaaagtaca agagagatga tatccatccc accagttgta aagcccattt ttaaagataa
     6661 tcctacgcca agacctaata aaacaccgcc tactagggca ttcatcaaaa tattatcagt
     6721 gatctgtccg actggaagca gcatcgtcat caccgataca catacaacat tcacaaaact
     6781 aaggatcgtt gctcgttttc ctactttgag aaaccctaat acaaacacag ggatattcaa
     6841 aagaaaaata aatgttcctg tgtctatctt gatatgaaac cattcatata aaagcgagga
     6901 aatgatttga gcgatcccat tcatccctgc agaaaagaca ttggctggaa tcaaaaaata
     6961 atttaaagcg accgcagcgg tcaatccggt tatcaaaata accactattt tctttaatct
     7021 ttcattttta tgatacgcag tcataatttt actcacaagc acctctcccc tactttggta
     7081 ttccaaatgt aagaataaca gtttatctat taaaataaaa tacttcgaac tcaaatgaga
     7141 agaattttag caaacaggta agaatctgcc ctaatcctat gataagatag atgtatggta
     7201 aatatttata tgtatatcag gagggttcct atggcaaaag atgctagctt cgacattgta
     7261 tcagaagtca atacagaaga agtaaaaaat gcgattcagc aaacaacaaa agaattgtcc
     7321 aatcgctttg acttcaagga ttctacagta gaaatcaaat tagagaacag caatctagtt
     7381 gtattgagcg atgatgattt caaaatcgaa cagatcaaag atgtattatt tggtaagctg
     7441 atcaaaagaa atgtgccaat caaaaatatc catttttccg aatcagaaca cgctctaggt
     7501 ggcaaagctc gacaaactgc cgatttggtc aacggaatcg atcgtgaaaa cgcgaagaaa
     7561 atcactacag ctatcaaaaa tgaaaaactg aaagtaaaag cacaaatcca agaagatcag
     7621 attagagtga caggtaagaa ccgtgatgat ctacaagctg tgattgcttt attacgtaaa
     7681 cttgacttac caatcgagtt gcaattcact aactatcgtt aatcaaaaaa cgaggctgac
     7741 gtctgtcatt cctcgttttt ttgatttact gcttcttttg ataaccaaaa acgctgtatt
     7801 ccttcttcca attccccaac acttcgtact tctcttgctg tttgccaatg ttgtgggaat
     7861 aaacgtcgat aagaaaaact agaaaatcgt tgatctgcca atacaacgat tccttgatcc
     7921 gccatgccac gaatcactcg accaccagct tgcaagactt tgttcattcc aggaagctga
     7981 taagcgtaag caaatccaag gtgttccttc tcatcataat atgatttgat cagttcctgc
     8041 tcatgattca tctgcggcaa acctacacct acgatcatac tgccgatcaa tcggtcccct
     8101 ctcaaatcga ttccttctga aaaaatcccg ccaagtacgc aaaatccaat caatgtttca
     8161 gcgggatttg tttgaaattt tgttaaaaat cgttcgcgtt cttcctcatt catgtccgtt
     8221 tcttggatta gcacattgct gtcgggatat tgctgtctga atgcttccac cgcaagatct
     8281 aaatattgat aagaaggaaa gaaaacgaaa taattcccga cctttccatc agcaaaagca
     8341 tgaatcgtct ctactaattt tgccagactg tgttcccttt ttcgataagt cgtctctagg
     8401 taatttgcga tgaaaacttg ctggtttcct tctgggaaag gactcggcag tttgtaagcc
     8461 agactttttt gtcccccagt gtttcctgat aataagagag tggtgaaaaa ctagcagaaa
     8521 aaagaatact gctttttcct ttatccaacg actgctcaag aaacaagctt ggatcaatac
     8581 aaaactcttt tactatcaga tcgcgatacg ttttttcgac tgttgtttcg tagtgatcat
     8641 cataaaattc actgaccttc aaaaaatgaa gcaaatcaaa ataataagga agcaattgtt
     8701 cttgtgatgg gtgctcagga aattctgcca gccattcttt aattttttcg cttaattgat
     8761 aacctgcctt tactaaagat tcagccggtg ctttttgatg atgataatcc caatgatctt
     8821 cttttgctat ttctcggatc gaatcaaatt cttttaatag tttgttgaaa cggcgatgaa
     8881 gttttttgaa ttcctttggt atagcttcct tacttcgttt cgttttttca taagatagtt
     8941 ctgccgaata catctctcgg gaacgattca ccaaattatg tgcttcgtca atcaaaaaca
     9001 gatagtcctc gtttttttca tcttcaaaaa aacgtcttaa ataaacagtt ggatcaaata
     9061 aataattgta atccccaatg attacgtcac accagatact gacatctaat gatagttcga
     9121 aaggacaaag tgtatgcttt cttgcataag tttcgatgac ttcacgagtg atctgattct
     9181 catgattcaa aagatcccat aaaccttcat taatccgatt gtaataacca ttggcatatg
     9241 ggcactgatc tggattacag gtcgtctcat ctaaaaagca gatcttgtct ttcgccgtca
     9301 aagtgacact ttttacttca gctcctgtat cttttaatgc tgtcatagca tcttcagcta
     9361 cttgtctagt tattgtttta gccgttagat aaaagatctt ttctccctct tcttccccta
     9421 cagctttcaa agcggggaat aacgtagaga ttgtttttcc tgttccggta ggtgcttcta
     9481 caaacaattt ctgtttcgta cggatcgttt tataagcagc taccgctagt tcacgctgac
     9541 ctttcctata ctcatcatgg gggaatttca aagccatcaa agaggcattg cgtacagtgc
     9601 gccagttttc ttgaaaaaca agccattctt tataatcttc agtcagcttt ttaaaaaaag
     9661 tttctaactg ctctcttgtc tgatgttcaa cctttctcgt gatcacttct tctgccgtct
     9721 ggaagtaagt caattgcaga tttatttctt gtaaatcatg ttcttgacta tagatatagg
     9781 catacaccct tgcttgatga aagaaaagtt ccacttgttc tggttctaaa tcttcaaatc
     9841 gtggttcgga ggttttgatt tcatctatat aataaatacc gtctcttttg aaaataccgt
     9901 ctgcacggcc ttcaacgatc aggtaatatt catctaattg aactgttgtt tttaaaaaga
     9961 cttctttttc atagttttct cccgcatctt tttggagctt gcggtggatt ctcgctcctt
    10021 ctaatgcagt atggttactt tttttacgat tgtcgatact tccacgtcgc aaaataaatt
    10081 ctactaagtg ccgcacagat atttttgact gtttgatcat ttccaccacc tctttctctc
    10141 taagattacc tgaaaaaacc tagtttagca aaaagagctc tctttccaaa cataaaaaaa
    10201 caccctgctg attaggcagg gatataggat atagaatttg gatttttgga tgaatctaat
    10261 gtaacaagga catattaaaa tgctatgaaa acttactttc cttctcttta gaatatccaa
    10321 atacttttca tatagtctga taattcagat aagtaaagag aaataagtac ctgtttttgt
    10381 ttcctagcaa tgaatgcgtt atactaatgg atgaaagaag ttttggctat caaggaggaa
    10441 tgcacatgca tatcgaaaga ttaaaaacag gaatgattga agaaaactgt tatttggtct
    10501 acaacgaaga agcacttttg atcattgacc ctggagaaga tgcggaacga atcaaacaag
    10561 aaatcaaaaa aacaaaccaa cagccggtag cgattttgct tacccatact cactacgatc
    10621 atatcggtgc agtggaacct ttacgcgcgt attatcaaat cccagtttat gtcagcccac
    10681 tagagcaaaa atggctaggt gatccgattt tgaatctttc tggactcggt agacatgatg
    10741 atattgctga tgttattgtc tcgcctgcag aatatgaatt tgaaatgaaa acttatactt
    10801 taggaaacat gtcttttcgc gtcgtcccta ccccagggca ttctatagga agcgtcagct
    10861 ttatttttga tgattttgtc gtttctggcg acgccctgtt tagaggaagt atcggtagaa
    10921 ccgatctgta tacagggaat ttagaacaat tacttcatag tattcggacc cagctgtttg
    10981 tattacctga tgaatttgca gtctatccag gacatggcga tgcaacgacg attgaacagg
    11041 aaaaaaggac aaatcctttt ttcaatcgtt aaaacgactt aggaggagaa taaaatgaca
    11101 gaaactacac tttatatcgt acgacacgga aaaacgatgt tcaatacaat tgaacgagta
    11161 caaggctggt gtgatacacc cctcacaaag caaggacaag aaggcattca ttatttaggt
    11221 cgcgggttaa aaaatgtcga cttttcattt gcttattcta gtgacagtgg tcgtgcaatc
    11281 gaaactgccc gtattattct aggagaacat tctaagggaa aagaaattcc ttattttatt
    11341 gaaaaaagga ttagagaatg gtgtttcggg tctcttgaag gtggatatga catggaaatg
    11401 tggggtgtga tccctcgtgt attgaatttt aaaacatatg atgaaatgtt taccacagaa
    11461 gtttcttttg aacaaattgc taatgctgta tacaacttag ataccgctgg gtgggcggaa
    11521 acttatgaaa cattgcgaga ccgtgtatgg acaggatttg aagatatcgc ccatcactgc
    11581 gaaaaaaatg gtggtggaaa tgttttagtc gtatctcatg gtttgacgat cgcctttttg
    11641 cttaatctga tcgatcctaa acagcctgtt cgtgctgggc ttttaaatgg cagcgtaaca
    11701 aaggtcactt atgcaaacgg tcgattttct atccacggca tcaatgatac gtcttatatc
    11761 gataacggga aaacacatag tcgcgactcg tttctataat ggggatattt taatttttac
    11821 cagagaatca taaaaggcaa agtctgaacg agggctttgt cttctttttt ctcttcgtgt
    11881 acttatctgc tttatttctc aagtttttct taatattaaa aaacagattg ggtttctcaa
    11941 aaaataacgg tatactataa gatgtatctt aattgggaag gaaggaattt atgttttttg
    12001 caaatattat caaagcagtg attctcggta ttattgaagg aataacggaa tggctgccca
    12061 tcagtagtac tggtcatttg atcctagcag atgaattcat caaactggat gccagttcac
    12121 aatttatgtc gatgttcaat gtcgttatcc aattaggggc gatcttggct gtcgtcgttc
    12181 tttattttca caagttaaac ccattttctc caagtaaatc aacggtagaa aaaaaagata
    12241 cgtggacact ttggtttaaa gtgatcgttg cttgcatacc agccatcatc attggtttgc
    12301 ctttggatga ttggttagaa gcaaatttcc acaagttctt accagttgcc attgttttga
    12361 tcgtttacgg tattgccttt attattgtcg aaaaacgcaa caaaaacaaa acacctcgtt
    12421 ggacttctct gaatgacttt acgtaccaag cagctcttct tgttgggtta ttccaagtct
    12481 tggcacttgt tcccggaaca tcccgttctg gcgcaacgat cctaggatct atcttgattg
    12541 gtgcttcgcg ttttgtcgct acagagtttt catttttctt agggattcct gtcatgtttg
    12601 gcgcaagcgg cttgaagatc gtcaaatatt tagctgaagg gaattcattc aaaatggaag
    12661 aaactgttgt tcttcttgta ggaacattcg tatcttttgt ggtttccgtc ttagctatca
    12721 aattcttact aagctatttg aagaaaaacg actttaccgc ttttggctgg tatcgtatta
    12781 tccttggtat cattttgatt ggttattggt ttattgcaat gtagaaaaaa ccagaacact
    12841 tctcttattt gagaaatgtt ctggtttttt attttcttta ataataatca ttataaataa
    12901 taaaaacaac atcaagctta atcaccaaat gataaccatt atcgttctca tttagctgtt
    12961 attattatca attacatttt tattatgcta tccttgtttt gacaaggagg tctaataacg
    13021 atgactaatc agaaaaaagc ttttgcagca acaatcggct gccttttatt tatgatcttc
    13081 ggttttatct tcgaccgatt ctctcttacc atcaccccac ttttttatat cagtgccatt
    13141 atcatcggtg gatataaaca aacatcggaa ggcttgaaag aattgtggaa tgatcggaca
    13201 ctgaatgtgg atttattgat ggctttagct gctattggtg cctgtttgat cggtaattac
    13261 tttgaaggag caatgttgac attcatcttt tgtttaagcg gtgcattaga ggaatacaca
    13321 actaataaaa gtcaaaaaga aattactgct ttgatgaatc ttcaaccaca aaaagcccaa
    13381 ttattaaaag aaaatggaca aatgcaagaa gtagatgttt ctcaactaaa ggtggataac
    13441 ttggtatttg tcgctaaagg agcagctgtt ccgatagatg gcttttcaga aagcacacag
    13501 gcaacgatcg atgagtctgc attaagcggt gaatctgtgc ctgtagaaaa atatttaggc
    13561 gatgagatgt atgcaggaac gctgaatcaa ggaaatccca tcacgattcg agtaacaaaa
    13621 acgagttccg aaactgtctt tgctaagatt atccaattag tagaagaagc gcagaatacg
    13681 ccaactcaaa cagcttcatt tatcgaacga atcgaaaata attatgtaaa attgattttg
    13741 cttgctgttc ctctaatgat ccttctcccc cactttttcc taggttggag ttgggatgaa
    13801 agcttttatc gaggaatggt attattagtt gtggcttctc cttgtgcgct tgtcgcatct
    13861 gctacaccag cttctctagc tgctctttca aattctgcaa aaaatgggat tttaatcaaa
    13921 ggcggtatcc atttagaaaa gctttctgaa ttaaaagcga ttgcctttga taaaacagga
    13981 acgctcacta aaggaaaacc agttgtaact gacagctttt tctttgatga aaaggatttg
    14041 gcacaacaac ttcttgttgc tatggaacaa aaaacgacgc atccacttgc tcatgcgatt
    14101 ttgcaatatt tcgattgcac aatacctgaa gaaatccaat acttaccaat agaagaaatt
    14161 actggttttg gattacaaac tacctattta ggtgcgcaat ggaaagttgg caagcacgca
    14221 tatgatcctg agacgatgat aatcagcaaa gagattgcgg aaatgatcga acgtttggaa
    14281 aatcaaggca aaaccgtgat ttatctttct aaagatcagc agttaattgc tgttttaggt
    14341 ctgctagata ttccaaaagc aaatacccaa caagtaattt cctactttaa atcccaaaac
    14401 atccatacaa gtatgataac cggcgaccat tctggcacag caaaggccat tgctgaacaa
    14461 gtagggattg aacattacta tgcaagctgt actccggaag aaaaaacaca actagtcaaa
    14521 aaagagaatg aactttacca agtaaatgcg atggttggtg atggagtcaa tgatgcgcct
    14581 gctttagcag ccgcttcttt aggtgtcgct atggggcaag ggacagatgc cgctatggat
    14641 atcgcagaca tcgtcttaat gaaaagcgac ttaaataaat ttgtctacag tcatcggcta
    14701 tctttaaaaa tgcggcggat catcaaacaa aatattattt tttcgattct tgttattctc
    14761 ttgttgattg cttctaactt cctgcaattt ttaaatctac ctcttggagt tgtaggacac
    14821 gaaggaagca caatattggt tattctgaat ggcttgcgtt tactaagacc tttacctgat
    14881 ctttctgatt cttcaaaaaa atgtaagtct tgtccactat acaaagcgcg gctgtcttct
    14941 gtcaaataag caaagtgttt ttttatgatt ttgtttattt tatgaaaaaa acagcttatg
    15001 aataggtctt gaaggatgaa ttcctacttt tgtaactttc taaaaacatg ttatgattgt
    15061 ttcgaagaaa gtgaggaata tatttcatgg aaagttggct ttttttagga attattttac
    15121 ttgtagcaat tttagctaaa aatcaaagtc tgatgatagc ggcagctttt gttttgatta
    15181 tgaagctcat accagcctcc cgttcctttt tcccttggct tcaaggcaaa ggaatcaata
    15241 ttggggtgac gatcatcaca gcggctattc taatccctat cgcaacagga gaaatcggtc
    15301 tacgtgatct attagaagcc tttaaatccc ctattggctg ggtagctgtt ttttgcggtg
    15361 ggctagtggc tgtcttatct tccaagggtg taggattgat tgcttctgat ccacaaatca
    15421 ctgttgcact tgttttcggc acgattttag gtgttgtctt cttaagagga atcgccgccg
    15481 gaccggtcat tgcttctggt atcacttact gtatcttaca agtatttgct ttaggaaaat
    15541 agaacaaatt ttgtctattt taggagattc ttaacacccc caatttactg atccgtgata
    15601 tactgacaac gaggtgatac aatgttcgaa aaattaaagt atttcatagg aacaatcggc
    15661 tggtttcttc tagcggtact tttgattctg ggcttagctt atctattatt tcctgatttg
    15721 atacaaaatg tgtttgatac tgctttttga ttgacctatt aaaacgatat aggggatgct
    15781 cctgcgatgc aggggctttt tttaatcaat gttttgtaat aatttaggcc gtgccaatga
    15841 gacttcctat agaattcgat gctctttttt ctttttggct cttctgctct tttttgttat
    15901 actagattac agtggacaaa agaaagaatg atcgcatcca cttcaacgaa tatcaaaatg
    15961 gaagaattag tgcctgtttt caggttactt tgaaaagaaa ggaagacgct tgtggaaact
    16021 tttgaaggtc ttttaattga tacgtacgtt ttacaagaac agccaatgat gctgactggg
    16081 atcaacttgc agcttgagga ccgtgtgatc aatggcctgc ttaaagatcg ctatttggca
    16141 aaatatatct tacgtttgcc cctaaataaa tatgtgctgg aagtaagtgg caaatggaac
    16201 cgtcggaacc agttggtcat aaaaaaaatg ttgataaaaa atatcgatga atacattaaa
    16261 ataatcggta caccagaata gcctttactg atcaaaggat actggttata aaataactgc
    16321 agtttcttaa tagaaaaaca aagaacaaca gggaatcgta tcccttttca aaaaaaactt
    16381 tgcaaacggt tctctttgtt atataataac ttagtaccaa acattcccat tcaaactttg
    16441 tttaaataga taaataaaaa tctagtttgg tttgacgcta ttgcctccca caatagcgtc
    16501 tttttgattt ttttcagctt gtactatccg tttttactga aaaaaaatcc taataaaaga
    16561 ctgttaagga aaaaaacttg tcatgttcat attgcaaagc acgctgcctt taggtataat
    16621 aatgaatgtt gaattatgcg gtaacacgcg taagaactta agttatcgga ggtgaaacta
    16681 atgccaaaca ttgaatctgc aatcaaacgt gttcgtacaa gcgaaaacgc taatgtgaaa
    16741 aattcatctc aaacaagcgc tatgcgtact gcaatcaaaa aatttgaaga tgctgtagct
    16801 tcaggtgctg acaacgtaga tgcgttatat aaagaagctg ttaaagctat tgatatggct
    16861 gaatcaaaag gtctaatcca caaaaacaaa gctaaccgcg acaaatctcg tttaagcaaa
    16921 aaaatcgcta aataaaagaa tcggcttcgg ccgatttttt tatttgtcaa aaaaaggaca
    16981 aaaacaaacg accttcccgc atgctttgcc ctcgtctttc ttcttatcga tttcttaaca
    17041 actgccctgt gcgcaaaacg aatagttgaa aacttaattc tttttcgatt tgtcccgttt
    17101 tgatttgata atccatctca actaattgat caaacaactg taccagcaaa tgttcatcga
    17161 atttttttac ttcctgcatg gcaagtttta cacgatatgg atggattttc aatgtttcag
    17221 caatatttgc ctgctgataa ccaatcttta caagaaattt tgtctgtaaa aataaacgta
    17281 attgagaaag caaaatcgca ttaattttga ttgtttcttc cccttgcata actaaatctt
    17341 cgtataaacg caaagcttgt tccgtcttcc cttttaaaat atattgggtc atgtcaaaaa
    17401 tattatgttc taacgtttta ggaactaatt cttctacttc tcttaccgtg atttgctgtt
    17461 gattttgtcc ataaaggacc aatttctgta actctctcat cattttggat aaatctaagt
    17521 cggtcaacct caagaataaa tcaattgcac ttcgttccat tttgattgag gaattctcta
    17581 aggtattcat cagatattga cgtacttctt tttcattcaa ctgttggaca ttgatgataa
    17641 ttgctgtttt tttcaattgt ttcgttactt ttttccgttc atccaacttt tcatatggcg
    17701 caaagaatac taatacagtc gattctaatg gttctttcaa ataagccgtc aataaatcag
    17761 tattttgttc gattccattg tttacttttt cacctgttaa aaaataagga ttctctacga
    17821 atactaaccg ttgatctccg aaaaacggca acgtctctgc ttcagctact acctcatcta
    17881 aacttgcatt ttccatgtca aaacttaaaa aatttaagtc atcttcgccc tctaattgga
    17941 tttttttgac aatttctgtc cgaacttgat cttggagaaa cttttctgtt cctaaaatca
    18001 agtaacaaga tgcaagtttt tctttacgta ttttttgtaa ctctgcttgt atactcaaat
    18061 tactcaccac tttcaaaaat tatcctacca tgagcagatg agaattacta gtctatcatt
    18121 gtttccacta gcccatgagg atgaaaaact ggatgccagc gataggtgat cattccttgt
    18181 tgatccgttc gccatgtttt tatctgattt tcttctagtg tctccaatac ttcgctgtgc
    18241 gggtgaccat aacgattatt tacgccgcag gatataatcc catgttttgc ttcaatatgg
    18301 gaaagaaaat ctgtgttact tgacgtacgg ctaccgtgat gacctaattt gactacatcg
    18361 gctttcagat taggataaat caaaagcaat tgtttttcca ttgcttgatt caaatctcct
    18421 aaaaataaaa agcgcctatt gttatattcc atccatagac caatcgaatc ttcatttctt
    18481 ccctctccct tttcaaaagg agtcaataca taaagatcat aataaccgct gatcctgtcc
    18541 ccatgtttga tttcaatgat ctcagtacca tttttttgag cttcagataa atgcctttgt
    18601 aatggctcat ttcgtccagc gccccaaccg atataaattt ttttgatagt aaaatgctga
    18661 gataacgtgg gtaattctcc cacatgatcc gtatcgtcgt gtgtcaagat gagtttatcg
    18721 attacactta tcccctgacc ttttagatat ggaacgatat ttctttcagc aggaggacgt
    18781 atcatacctt gcgcccactt ttctctttca aagtgtaact gacctccagt atcgatcaaa
    18841 atcgtttctt ttcgaaaagg actttgcaaa aagatactgt ctccttgacc gacatcgata
    18901 aaagcgatcg ttgaagaaaa gcgtaaaaat ggcaaagtca aaaaaataaa agaaaaaaga
    18961 ccaacataaa acaagtgttt cacaggttgt tctttcaacc tatccataca aatcagtaat
    19021 ccgaaaatat acatcccaga tagcacaagg ggcaaacgtc ctataatgag agacgaccct
    19081 gaagaaaaat cgattattcg ctcaaataag attaatccct cttctatcag caaaagtaaa
    19141 gtttccggca gccagcgatt gaagagtgtg agaaataaca caccaggaag aaaaagaaac
    19201 ttgaataccg gtgcaatcag taatgtaaaa agactaccta aaataggcca ctcataaaaa
    19261 tgccatacaa tcaacggcat cgtgatcata gtaaacagga cgtgagaggc cgtttttttc
    19321 aaccaatctc catcaaaaga aatcaggata aacaaaaaac tcatgaaaaa actaagctgt
    19381 ccacccgcat gaaaaagaaa tcgaggatca aatagtaaaa gaagccaaaa gacaactgca
    19441 aataagtcca tggtggaata atgcttattc agcaatttga ctagcaatcg caataaaaac
    19501 agcaaactag cacgcaaaac agaaatagaa cttcctgcaa tagaaacata acagatagtt
    19561 agtagactca acggaataat actgacgtgt agtggccatc cgatacgtcg aaataaataa
    19621 tacagccacc ctaaataaaa ttggatgtgt agacccgata gactgaacag atgcagcaaa
    19681 ccactctccc taaaaatttc ttctggttct ctgaatcctg catctttata gccccataat
    19741 aaagaattaa tatatacact tgttttttgc ggaaattcag attggacaaa ggagataaaa
    19801 gatcctcttt ttctctgaag ccagtttcgc cagtgatttt gcatggtgat ctgttcaatc
    19861 ttttgaattt ggaaccgtcc agaaattcta tggttcctga agtaagcttc ttggtcaaaa
    19921 ttataaagat tccgcttttt tgctggagag atgaactcgc cttcagcagt caattctatt
    19981 ccctttcctc ggaagttaag ccatgttttc aattctgctt ctgtgtttac ttgataagaa
    20041 agctggagct tttgtttatt ctctgataac cttccttcca ttgtcaaaaa attaccattt
    20101 gcacgaatcg tatctgtaaa tacagtaatt tgcgcagatg ttgttttttc ctctaaaaat
    20161 gaatactctt gtagcctata agaaatggat accgttatgc tacacaaaat acacaagtac
    20221 gcgataaaac gtccttcttt tagcgaaaac cataaaaaaa ttccggcaag aagcaaacga
    20281 taaccccaat tgtcagtgta atacaacaaa cagataatca tcgacgtaat tgccggaaaa
    20341 atcaaccgat ttcgaacatg cctttctaaa acgctagaca tgttttcctg ttaattcatt
    20401 ttgaagtttt gaaaaatgct gtgagtctaa agcaacttgg tgtacagata cacctaattg
    20461 ttcgatcaac gcttgggcat aaggatcatt tcgatagtca tggagataat tgatcccttt
    20521 cacaccagct tgcaacaaag cctttgtaca ggccaaacat ggaaaatgtg tgacatagat
    20581 ttctgaacct tccgtcggga taccaagttt tgcacactgt aggagtgcat tcatctctgc
    20641 atggatcgtt cgcaagcagt gtccatccac gacgtaacac ccttcatcta tgcagtggac
    20701 atctccactg actgctccat tatagccgcc agcaatgatc cttttttctc gaacgagtgt
    20761 cgctcctact tctaaacgtg tacacgtact acgtaaagat aacagtactg cctgagccat
    20821 aaagtactgg tcccaaggaa tgcgttcatt atgtgactta tcagtaactt tttctttatt
    20881 cgtatcgcat gcttttgaag atttttctaa catgttttat attcctccgt tttttcaagt
    20941 tgattaaaaa gtactcattg cttaaacaaa atattcttta aatataacga atcatcctgt
    21001 ctgacaaaag atcctaccct tcactgccga aatgaagtcc gtcatccatt agcccattat
    21061 aaaaattctt cgaatccatt tgttcaagaa attccgtata aaaatcgata cttcacaatc
    21121 atggcgtttt gctacttctg tgagaacaga gatatattct ttgatcaact tgttattccg
    21181 atatttttgt tttgtctcat cgactgctgg tggcgtgata aagaaagcat gatcagaact
    21241 atagtctttt ttcagctgaa ctatcatcca ctgcagattt tttggtacgt ttctttagaa
    21301 agttgtttat gctctgctag atcattcgtc ccaatgagaa taaatacttt atctgctgta
    21361 tagctaagta catctttggc aaagcgttct cgtagagctt gactgttatt gccgctgaca
    21421 gccgtattca taatatgaat cccagatatt ttattttgga gatagacatt cagcattggt
    21481 ttttttaatg tttctttgcg aacaatcaag ctatttccta tccaaaaata ctacctcctc
    21541 gtcctgccaa gctcttagaa ttggattatt cttagtatcc attagcgtcc atttattgct
    21601 cgtgccagtc gattttgaat cattctattt aattgtaacg aagtttttta gtttttcaac
    21661 tgtcttttca ccgataccag aaatctcctg caggtcttcc actttctgga aggatccgtt
    21721 ttcttctcta aatcgaatga tttcttgcgc tttgactgat ccgatcccag gaatctgctg
    21781 aagttctgat ggagtggctg tattgatatt tattttggga ggctcggaat ctgctgtagg
    21841 ctgttttcct tccgaggatg ccaactgatc aagatgttct ggcagctctt cacctacagc
    21901 agggatatat aggacttgct gatcttctat cttcgcagaa aagttgattc gatcgctatc
    21961 cgcttcttct aataatccac ctgcacgctt tagtacatca tagacccgtt cttctgaaga
    22021 aaaggaatag ataccaggct ccttcacact tcctttgata tcggtgtaca tgacctttgg
    22081 acgagcatcc tcttctacat cgtttccttc agctgatgga tcttctccac tggaactaaa
    22141 cgaagaaagt atttcttttg cagcagtctc ttctgtttct ctataaaata gcaaatttga
    22201 taataaaaaa ccacttgcga tacaaaagat aagaactatc atagacatcc aaatgatcaa
    22261 tttgggtgaa gctagtattt tcttgctgat tttttctatc attgttcttt tttcaaagaa
    22321 tgaccagtaa aaatcattca ttactccttt catttaaaat tgaagaaaca gtgagctctg
    22381 gcaaaatcgt cccttcaaca tctaattacg tcaatttttt cttttgtttt tatttttatc
    22441 gtgaagattt ttgacgaaaa agaggggttg tgacagaact cgtgtcacaa cccctcttta
    22501 attatttagt ttcatttcat tttctctaga tagtcaagcg cttcttgtac tgtttttact
    22561 ggtacgattt tcattgagga attcaatttt ttagcggcag cttttgcttc ttcgtagttg
    22621 gtttttattt caggatattc tttcttaaca tcgtctgaaa tcgtatcatc tggtgcaaag
    22681 aaaatctcta cgccagcttt atccgcactt gccacttttt tatcgattcc tccgattcgg
    22741 ccaacttctc cttcactgtt gatcgttcca gttcctgcaa tttgcttacc atgtcgcaag
    22801 tttttaccag tgacttgttc atagatttct aaagtgaaca tcaatcccgc tgatggccca
    22861 ccgatagagc cagaattaat acgaacatct gtatctgatt cgatctcggt atggtcagta
    22921 agcgtgatac ctattcctgc ctttttatct gttggtaact cgatcagatc accagaagct
    22981 gttttttctt caccattatg caaataactg atttcgattg tttgtccaac tttttggctt
    23041 tttacataat ccataaatgc ttctgtactt tgaaagcttt tcccgtctac ttttgttact
    23101 gtatctccaa ctgaaagctt gccaaagaaa ttcgatgttt tctctacact catgacatat
    23161 acgcctttga attccatttt ataaggcttg tctgcaagtt ttaacgcttg ttcgattgct
    23221 gcattttggg aagaatccat ataatactgt tgcatttgat tatattcttc atttgtcgcc
    23281 ccaccagtca attcttcttc actgatcaat tcttcaaaag gggtcatttt agcttttaaa
    23341 gctaagaaac ctgtagcttg cctgatacca acagaggtaa gagagaaaga cccagaacct
    23401 ttatcttcct tatcattgac cgtaattagt tctttcagat cgatcgtggc tcccggtgat
    23461 tctacataat acggcaaggg aactactaca aatccaatga tcaacattcc aaatatgata
    23521 atcagtactg ttttcaacca ttgtttagct ttcatttgat tcacgctttc cagctaaagc
    23581 ttcgttgatc actggcggta agtagctgct cacatctccg ccaaagtgca gtacttcttt
    23641 taaaatactg gaactcacgt gactatattc tggttttgct aataagaaga cagtttccaa
    23701 ttcatcatat agatgatgat tcatctgagc aatctctcgt tcatattcaa agtctttgat
    23761 acttcgtatg cctctgatca acgcatctgc accaatctct tttgctgttt ctaccgtcaa
    23821 ttgattttct tgatgcatga cttttacatt aggaagatga gaaacagctt ttgtgatcaa
    23881 tgtcattctt tcttctgggg gaaacaaatt tttctttgaa gtattgataa aaacaccaat
    23941 tactacctca tcgaataatt tagccgcacg ttccaccgta tctaagtgac cttttgtaaa
    24001 aggatcaaaa cttcctggga ataatgcacg tttcattgat ttccctcttt tctatagata
    24061 gttacggccg ttatgccata aatctgtttt cttatttgat ggaatccagc cacagtttct
    24121 ggcaattcga ctgttttatc cgtttcgcat acgataactg cggttttaga aaaaagtccc
    24181 agttcttcca ttttatggat ttgatcgatt attttttgtt ttgcatatgg cggatcaaga
    24241 aacaagtagt cgaattgttg tttctccgct gctagccgtt cgattgcttt gtccgcatca
    24301 agttttattg tggtaaattt ctctggttct ttcgtaattt cgatgttttc tttgatgatt
    24361 tttagcgctt ggtaattttt gtctacgcat accgcatgac tgcagcctct agatactgct
    24421 tcgatagcta aaccaccgct tcctgcaaac agatccaata ctgtctctcc atcaaaatat
    24481 ggtccaatca tattgaatat ggattctttt actttatctg tagttggtct ggtgttcgcc
    24541 cctgctaaac tttttaaacg gcgcccgcca taatttcctg atattatccg catctactca
    24601 ctccttagaa atggtactgg tactagtata ccaaaaaaat acttggacaa tgatcaaaaa
    24661 tcgatcgtta tccaagttat tttttattta aaaactgctc ataagagatt tttaaagatg
    24721 ttcagctaat cggatttctg tatttagctc ttcaatttcg aaaccttcgt cttttaatac
    24781 tgttttgttt cctatttttt cggcaaaatt catttcgata tccggtcggt aagaacgttc
    24841 tacgtttcga acaaaatgta atttacggat tcgttcttct gtttcttcca atgtctcttc
    24901 atttaagtaa agcacgacat atttcattct tcttgagaca taatgcaaca agccgaactt
    24961 tttcagattc tttaattgtt ttaagctgta gacccatacg atcagcccgc gtcgttttgt
    25021 tatttcaaat tcactattgt ctaattgcat gacaattacc tccgcatcca aagtgttttt
    25081 tcgtttcaaa aaacgggcta cctgcatcta ctttgatttc attagaaact tcttcggcaa
    25141 gtacttggac aatttgatcc aacagacttt gcagctgtgt ttcactatat cggaaagctg
    25201 caacatgctc atccatatca agctgtcttt ttgcttttcg aacagctcgt tttttttcac
    25261 gataatcagg tgcatactca ccatatgccg ctacattttc aaatgcttct ttcttagaca
    25321 agaacgcttc tttcaactgg caaacttttg cagattcttc cattgactgt ttatgttcaa
    25381 gataagaagc catcgtttta ctctttttta tcatttcagc gacttggagg cattgatcct
    25441 ccagttgaaa cagctcttcg ttaacgatca ctgctatcac tactttctcc gttttcttct
    25501 tgcaataaga ctaacatatt ttctttagaa aaagcaatgc ctacagaatc cgttcccggg
    25561 tccatgaaac ggtcatggtt gtaaggatcg ctgtaccaat ataaaaacga aaaagtagcg
    25621 tcaatcgccg gatgaataaa tagcccacta gtattttcta atttttgttt actgattaac
    25681 ttctccaatt catcattcgt cagtgagaat ttcactgtcg tttgagcact gcctagcgat
    25741 ttttgccaat cagccatacg ttcctctgac aatatttcct caggccttgt caaaaaatca
    25801 tgtagtagca gctgactgtg gttttgaaag gcaagtgttt gattgtatat gggaagttcg
    25861 tcttctcttc taagcatatt taataaagtc gtactttttc gttctttaac gcgattgatt
    25921 gattcccaat cagccgattt atctgcttga taatgtggaa ggccttcacc aaacacttga
    25981 tatggcaata gtttcaaaag actatcttta tctaaataca caactgaaaa taggccgttt
    26041 gttgtttgat caaaaaataa aatagcaaaa gtgtcgttat caaaagcaat tagcggacga
    26101 taattcatat cctcttccat tagttcgatt ccaacttctg tatcatggta ctcaaaagtg
    26161 aaattagtat agatagtagt gattttcgta agatcttgca tcgtcatccc taaataaaac
    26221 ggcgcgatat cagcaggccc tgtttgcagt actttaacag ttgtgactct gctgtcttgg
    26281 atgttcgctt caaatgtgag atgactagct ttattttcat aatatcttgt ttcaaaacca
    26341 aatccgctag ttaatcgatc ataggcttgg ccaaaatcct tttccagctg atcgatcggt
    26401 tttccgatat aagtagaaaa accagttgct ttaagctcct ggtatttcca cgttgtcatt
    26461 tggtttgata tttgttgatc agagttttcc ttcacttcaa gttttggcgg aaacaagact
    26521 ggttccatgt agaatgccac aataactaat agcagaatca gccaaaacaa acccagtctt
    26581 ttcatgtttc cccacctttc gcttattatt tctcagtcac ttcaatcaaa aggtcaccag
    26641 acgaaatagt gtctcctgaa gacacatata catgtgcgac ttctccgtca aaacgtgctt
    26701 cgatggccgt ttccattttc atcgcttcag taatcatcaa cgtatcacct tttttaacgt
    26761 tatcgccttt tttcactaat acatccaaaa cagaaccaga catcgttgct ccaatttgtt
    26821 ctcggtttgt cggttcagct ttcaatcggg tttggaccgt actgatgatc gaattatctt
    26881 tgatagtgat ttcacgtctt tgtccattca aattgaagaa cagtacgcga ttcccttcga
    26941 tatcgggttc tccgatttca tctaaacgaa tgataagcgt ttttccgcgt tcgatttgta
    27001 cattgattgt ttcacccaaa cgtatacctt ggaaaaatgt tggtgtgtcc agtaatgtaa
    27061 catcgccaaa ttgattatat gctttttgat agtccaaaaa gacttgcgga tacatcaaat
    27121 agcttaatac ttcgtcttgt tttggttcat agccaatttt ttctgccaat tcttttttta
    27181 cttcgttgaa gtcgactgat tcagccaaaa gacctggacg ttcattcaat gcaggtctgc
    27241 ctttaagaat aatcttttgc aattttttag gaaatccgcc aacgggttgc cctagttctc
    27301 cttggaagaa agtcacaaca gattcaggga aacttagtgt ttcgcctttt tcataaatat
    27361 cttcttctgt aagatcattt tggaccataa atagtgccat atctccaact actttagatg
    27421 atggagttac tttaacgata tcgccaaaca tcaagttgac agtatgatac atttgtttga
    27481 tttcatccca gcgatgacct aatccgacag cttttgcctg ttgctgtaga ttcgaatact
    27541 gtcctcctgg catttcatgc atatatactt ctgtttcagg agcattcaag ccgttttcaa
    27601 acggtttgta atacatgcgc acatcttccc aataatggtt taatttctgt gcattttcaa
    27661 tcgtgatttc tggcagccgt ggaccattga ccagtgcata atacaagctg ctcatgctag
    27721 gctgactagt attcccactc attgcactca ttgccacgtc aacgatgtct actcctgctt
    27781 ttgaagcagc agaataagtg atgattccat tcccgctggt atcatgagta tgcagatgga
    27841 ttggcagatc tgtcgtttct ttcaattcac taatcaaacg ataagctgcc tgcggtttaa
    27901 gcagcccagc catatctttg attgcaatga tatgcgcacc cagttgttct agttcctttg
    27961 ccatgtcttt ataatactga acattgtatt ttgcccgact tggatcgttg atatcgccag
    28021 tatagcaaat agctgcctct gcgattttac cagtatcccg tacagcttgg atactttttt
    28081 ccatttgtgg agtccagttc aaactatcaa agattcgaaa tacatcgatt ccttgcgctg
    28141 ctgcttcttt gacaaattcc accaatacat tgtcaggata attagaatac ccaacggcat
    28201 ttgaacctct gaaaagcatt tgcagcaacg tattaggcat taaagaacga atttttctca
    28261 accgttgcca aggatcttca ttcaaaaagc ggtaagccac atcaaatgtt gctccccccc
    28321 acatctcact tgaaaagagt tcaggaagac cttctccagt caaacgtgca atctgcttga
    28381 aatcctttgt ccgaacacga gttgctagca gactttgatg ggcgtctcta aatgtcgtat
    28441 ccgtcaacaa caaattttcc tgtcctttga tccattcgac caaagcatcg gcacccttcg
    28501 catctaatac attcttagcc gttacgtaat cagttcttgt gattagatct ttaggcatac
    28561 gtggttcttc ataaaatggt ttttcgccac tttcgatacc tggaaaacca ttcacagtaa
    28621 tttcaccgat atatttcatc gttttgtttc cgcggtctcg tagtcgagga aattcaaata
    28681 atgttgctgt actatcaatg aaggttgttt ttgcatttcc tgattggaat tcaggatgtg
    28741 tgatgacatt gagcataaat ggaatgtttg ttttcactcc acggattcta aattctttca
    28801 agcaacgttc cattttctga atggctgttt caaaggtagc accatgcgta catactttta
    28861 ctagcaatga atcaaaatac ggtgtcacta catagcccgc gtaagcattt ccgacatcca
    28921 gacgtacgcc aaaaccacca ggtgaacgat acgtatcgat tttccctgtg tctggtaaaa
    28981 agttattcaa cgggtcttct gtagtgattc ggcattgaat ggctgaacca tttaatttaa
    29041 ttccttcttg ctgaggcaat ccgatttctt tatgcagatc caaaccttga gcaatcaaca
    29101 gttgcgttgt tacgatatca atatctgtaa tcatttctgt gatcgtatgt tccacttgga
    29161 cgcgagggtt gacttcgata aagtaaaaat catctccttc aacaagaaat tctactgtac
    29221 ctgcgttgac atacccgaca tatttcatca attggacagc tgcctggcag attttttgac
    29281 gttgctgttc attcatagag acacaaggcg ctacttctac tactttttgg tgacggcgct
    29341 gaacagaaca atctctttca aaaagatgga tgacgtttcc atgcgtatcc ccgagaatct
    29401 gtacttcgat atgcttagga ttagcgatgt atttttcaac atacacttca tcactaccaa
    29461 aggctgcttt tgcttcgctt ttcgcacgtt cgtagccctc tcttgcactc ttttcatcgt
    29521 gagctacacg catgccgcgt ccgccgccgc ctagagctgc cttgatcata atcggataac
    29581 cgtattgttt cgcaaactcc aaggcatcgt ctatagaagc gattggtcca tctgtgcctg
    29641 gaatcgaagc aatccccgct tcgatagctg cagcttttgc tttgatttta tctccaaaaa
    29701 tatctaaatg atgcagtttg ggtccaacaa aaatgatgcc ttcttcttcg caccgttgcg
    29761 caaaattcaa gttttccgac aaaagaccgt aacccggatg aatagcgtca gctccgcatt
    29821 ctttcgcgat agaaatgatc ccttcaatat ctagatacgc atcaatcggt ttttttcctt
    29881 gtcctactaa atatgcttca tccgctttga aacggtgtac ggaatattca tcttcttctg
    29941 catagattcc aacagtttta attcctaatt ctgtacaagc acgaaataca cgtacagcga
    30001 tttcacccct gttagcaact aaaacttttt tcatcgaacc actcctacat ctttttttat
    30061 tataaaccta agctcttgcg tttttcatcc gcactgatgt tgaggacaaa gccgacacaa
    30121 atcgaaagca tcagcaaact ggagcctcct tgacttaaaa atgggaacgt gatccctgtc
    30181 aaaggaataa cgccagtaat tcctccaaga ttgacaaata cttggatcaa aaacattgcg
    30241 ccgatcccaa tgcacaaaag cgaattgaac ggatcttttg aacggatacc tacaaggaca
    30301 atgcgcacaa tcataaagaa tagcaacgct aatatcaaaa tccccataat cactcccagt
    30361 tcttccacta cgattgcata aataaaatcg gtttgtgctt cttgtaaaaa tccttttttc
    30421 tggatactgt tacctaatcc cctgccaaat agtcctccgt tgaacatggc atagtagccg
    30481 ttgactagtt gatgcccttt atttaattcg tctgagaaag gattttggta aatagcaaat
    30541 cgattataga tatactgtaa acgtccgggt aagatctttc cgtttgtgat attgatcagc
    30601 cagatcgtaa aagtacttag acaaaagcct cctactccta caatcaaagt atacacataa
    30661 ttgactccgc tggctaaaag cagaaccaaa ataatcaaaa agataactgc cgcattacca
    30721 aaatcgggaa gaatagcgac taatgcagta agtccgataa ccattgcaag tggacgtttc
    30781 acagtcccaa gaaaatcttt ttgtacactg ttttgtcttt tagataaagt cagagacagg
    30841 taccagatag aaatgatttt taggtattcg gcaggttgga tcgagaatcc tgcaatttgc
    30901 agccaacctt tcgccccatt gatctcctta ccaaaaaaca caacaatcag cagcaaaatc
    30961 gtcaaaactg cgatggctgc catgatcaaa cgctggtttt tcaaaacatc tgttttcatt
    31021 ttataaagta gtgcgatagc aatcaagcta agcacccaaa aaatactctg gttaatgact
    31081 gatgcggacg gattttgtcc gttttctaat aatagatacg acgtagaact atataccatg
    31141 atcaatccca atacacataa aattaaatag ggaatcaaga tgctatagtc taatagatgc
    31201 ctttttttca ctttcttagg caagtctatt cctccttgcc aacttctttt ttatcataaa
    31261 tttcttggta aacctcacta tataactgat tcaattctcg ttctagctca cttaacatca
    31321 gctggccctc gttctttccg attactccta tacggacagc aaaaccgact tgccgggaaa
    31381 agccgtacat ctgtgtatct accacttctt cgaaggcttt gcattgtgag atacagagac
    31441 tgttgttttg atttcggatt aatcgtttga tccgttctgc ttcatcattt aatacttgga
    31501 tcgcaagttt tttcgacaaa gaatccatct gtgcttacct cccattctaa ttccttaatt
    31561 ataacatatt tgattttcat aaggagcaaa aaaaacagat ttaaccagtt gtttttattc
    31621 atttttacgt attcgttctt tctacttatc cagaacgtta gagtccgcat tttttatccg
    31681 agataaaaag gcttcgccat atttatcaag cttgctttgg ccaactcctt ttatctgaag
    31741 catctccaat ctgcttgatg gacgtattcg gctcatttct ttcaatgtgg aatctgaaaa
    31801 tacgacatac gggggaacgc ctgcttctga tgctagatcc gttcgcagtt cccgcagcac
    31861 ttcaaatagt gtatcggttt cttcatccga tagctgctgg actttcttgg gttcctttcg
    31921 ataaacagat tcttgtcctt tcaatacttg tatccctctt tctgttactt tcaaaacagg
    31981 atactcacca ttgatggtca gaagatagcc attcgatatc aaatattcaa ttaactgcat
    32041 cgtttctttt tgcgattggt ttttcatcag tccataggta gataaatgtc caaaacctaa
    32101 agcttgcagc ttttgttctt tcgatcctgc taagactttc atcagcattt gtttaccata
    32161 gttctcaccc atacgtttta agcaagaaag aaccatctgt gcttctgtcg ttacttctac
    32221 tatttctctg tcatctaaac agttaccaca acggttgcac ggactgcttg tctcgccaaa
    32281 atagtttagg atgtattgct gaagacagga ctcaatatac acgtattctg tcatcgcttt
    32341 taatttttca tattcttttt gcttttgccc ttcttctctt tgggactgct ggataaaaaa
    32401 cttttggact tggatatctt gaggagagaa aagcaggatg gcttcactgg aaagaccatc
    32461 tcttcccgcc cgaccagctt cctgatagta tgcttctaga gagccaggaa tttgataatg
    32521 gataacaaaa cggacattgc ttttatttat acccatacca aatgcatttg tcgctacaat
    32581 cagctgcaag cgatcgtata aaaaggcttc ttgcatttct gttcgctcat tctcatttag
    32641 accaccatga tatctaccca cggaaaaatc gaatttttta agcaaatgat agagacggtc
    32701 tacttctttt ctcgttgctg cataaatgat accagattga tttttgttga tctttaaata
    32761 ttcgattaga tattgttctt ttttttgatc tttaattact tgaaatcgta gattttctcg
    32821 ttcaaaacca gtctgaatat ggttgttttc tggaattttt aaaagtcttt ttatgtcagc
    32881 agctacttgc acagtcgctg tagctgtcaa agcaacaatt acaggacgat ttggcagttg
    32941 atctagctgg ttcgccatct gtaaataact tgggcggaaa tcatgccccc actgagagat
    33001 acaatgtgcc tcgtcaatag cgatcatacg gacgttccat cgcttcattg cttggataaa
    33061 atccggcatg ataaaacgtt caggagcgat ataaagtaaa cggtactgct gtctatcgat
    33121 ttcttggaag cgtctagctg tttcgtaacc atctaacgag ctattgataa aagtggcggg
    33181 tatacctaat tgattcgccg cgtccacctg atccttcatc aaagagatta aaggggacac
    33241 aaccacagta agcccatcta atagtaaagc tggaagctgg taacagattg atttcccact
    33301 tccggtaggc atgattccta atacattttc ctgatcaatg actttctgga taatttcttt
    33361 ttgaccaggt ctaaactcat catagccaaa gtattgtttt aataagtcgt tcatcttccc
    33421 gctcctttct cttgccattt tacttcgatt ttcttcgaag gacaagttga tctcctttcg
    33481 tgaaacatta tcttattatg aaacaaaaac tctctagaaa taagtttttt aaaagtcttt
    33541 taaacgtctt tcggcgtatt ttctgaattt atgtccattg acaaagatga cttctccaca
    33601 gaaaagagtt ggacaaaaaa agaaaccagc tatttttt
//
LOCUS       DACDLM010000028        32534 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.028, whole genome shotgun sequence.
ACCESSION   DACDLM010000028 DACDLM010000000
VERSION     DACDLM010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.028"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            132..506
                     /locus_tag="IV356_001361"
     CDS             132..506
                     /locus_tag="IV356_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAP9015057.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(620..1249)
                     /locus_tag="IV356_001362"
     CDS             complement(620..1249)
                     /locus_tag="IV356_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAP9015058.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1383..1455)
                     /locus_tag="IV356_001363"
     tRNA            complement(1383..1455)
                     /locus_tag="IV356_001363"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1420..1422),aa:Thr,seq:ggt)
     gene            1669..1742
                     /locus_tag="IV356_001364"
     tRNA            1669..1742
                     /locus_tag="IV356_001364"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1703..1705,aa:Asn,seq:gtt)
     gene            1697..1846
                     /locus_tag="IV356_001365"
     CDS             1697..1846
                     /locus_tag="IV356_001365"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015059.1"
                     /translation="MTVNHDVVGSSPTAGVNKAYAKKKKSNHLGFFFFYYYDESSFLF
                     LSRML"
     gene            2339..3667
                     /locus_tag="IV356_001366"
     CDS             2339..3667
                     /locus_tag="IV356_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAP9015060.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3869..4702
                     /locus_tag="IV356_001367"
     CDS             3869..4702
                     /locus_tag="IV356_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HAP9015061.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4718..5455
                     /locus_tag="IV356_001368"
     CDS             4718..5455
                     /locus_tag="IV356_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HAP9015062.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5610..6578)
                     /locus_tag="IV356_001369"
     CDS             complement(5610..6578)
                     /locus_tag="IV356_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HAP9015063.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6810..7643
                     /locus_tag="IV356_001370"
     CDS             6810..7643
                     /locus_tag="IV356_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HAP9015064.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7677..8516
                     /locus_tag="IV356_001371"
     CDS             7677..8516
                     /locus_tag="IV356_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP9015065.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8542..9102
                     /locus_tag="IV356_001372"
     CDS             8542..9102
                     /locus_tag="IV356_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAP9015066.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9301..11022
                     /locus_tag="IV356_001373"
     CDS             9301..11022
                     /locus_tag="IV356_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HAP9015067.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11187..12329
                     /locus_tag="IV356_001374"
     CDS             11187..12329
                     /locus_tag="IV356_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAP9015068.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12345..13556
                     /gene="thiI"
                     /locus_tag="IV356_001375"
     CDS             12345..13556
                     /gene="thiI"
                     /locus_tag="IV356_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HAP9015069.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14129..14776
                     /locus_tag="IV356_001376"
     CDS             14129..14776
                     /locus_tag="IV356_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAP9015070.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     gene            15169..17814
                     /locus_tag="IV356_001377"
     CDS             15169..17814
                     /locus_tag="IV356_001377"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HAP9015071.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18124..19437
                     /locus_tag="IV356_001378"
     CDS             18124..19437
                     /locus_tag="IV356_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HAP9015072.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19427..20080
                     /locus_tag="IV356_001379"
     CDS             19427..20080
                     /locus_tag="IV356_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP9015073.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20135..20827
                     /locus_tag="IV356_001380"
     CDS             20135..20827
                     /locus_tag="IV356_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HAP9015074.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            20977..21177
                     /locus_tag="IV356_001381"
     CDS             20977..21177
                     /locus_tag="IV356_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP9015075.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(21431..23110)
                     /locus_tag="IV356_001382"
     CDS             complement(21431..23110)
                     /locus_tag="IV356_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAP9015076.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(23112..23324)
                     /locus_tag="IV356_001383"
     CDS             complement(23112..23324)
                     /locus_tag="IV356_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HAP9015077.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            23717..25447
                     /gene="efrA"
                     /locus_tag="IV356_001384"
     CDS             23717..25447
                     /gene="efrA"
                     /locus_tag="IV356_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HAP9015078.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            25444..27204
                     /gene="efrB"
                     /locus_tag="IV356_001385"
     CDS             25444..27204
                     /gene="efrB"
                     /locus_tag="IV356_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HAP9015079.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            27299..27496
                     /locus_tag="IV356_001386"
     CDS             27299..27496
                     /locus_tag="IV356_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015080.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            27649..28134
                     /locus_tag="IV356_001387"
     CDS             27649..28134
                     /locus_tag="IV356_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HAP9015081.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(28238..28831)
                     /gene="clpP"
                     /locus_tag="IV356_001388"
     CDS             complement(28238..28831)
                     /gene="clpP"
                     /locus_tag="IV356_001388"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HAP9015082.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            29011..29538
                     /locus_tag="IV356_001389"
     CDS             29011..29538
                     /locus_tag="IV356_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HAP9015083.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            29629..30366
                     /locus_tag="IV356_001390"
     CDS             29629..30366
                     /locus_tag="IV356_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAP9015084.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            30370..31287
                     /gene="miaA"
                     /locus_tag="IV356_001391"
     CDS             30370..31287
                     /gene="miaA"
                     /locus_tag="IV356_001391"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HAP9015085.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            31289..32518
                     /gene="hflX"
                     /locus_tag="IV356_001392"
     CDS             31289..32518
                     /gene="hflX"
                     /locus_tag="IV356_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HAP9015086.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT        10771 a         5523 c         6875 g         9365 t
ORIGIN      
        1 tctacactct gagatgtaag aaatatcata agatatttct tacatctttt tgttttgagc
       61 aggactttag ataattttat taatatatgc tagcatgctt ttgtaagaaa aagaaagagg
      121 gcgtattagt tatgtatctt aaaattacgg aacaagcaca agaaagatta caaaaatata
      181 ttgatgaagg cgcaacagtt atattggatt tagatgatgg cgttggggaa tattctaaaa
      241 tgggtgtttg ctctttagat actagttttc gtttacttct tcttgataaa gaacagagaa
      301 aaaatgatta taaactccaa ttagatagtg atattgggga tgtttatata aaagattatt
      361 caaaaatgta catggatgaa catatgaccc tttctttaga tccacgtcta ggtgtattta
      421 ctcttgaaag cccaagtggt tctttagaca gtcatgttca attagtagat ctacgaccag
      481 aaaaattctc tggaataaaa caataacttt ctctctattg tccataaaac tagtctcaat
      541 caagctgtat tgaaaaaaca agacaacatt cttaccatgg taaataaaaa gacgacacat
      601 tttgtcgtct ttttttaaat taactatttt cgataaaaga tcgcatagct tgtgccatta
      661 tttctggctt ttctctattc aattcatgtt ttccgttttt aataaagagt agccggccat
      721 tcgttgaaag tttatataaa cgttttgctg ctggtttatt cgcatgatct ttggtaccgc
      781 ataaaatcaa tttaggaagt cgtgatgtac gaagctgttt tttgcagtct aatgtttcaa
      841 gtgaacgaag tagggtaagg gtttgttttt tagatagacc taatttttca aatatcttag
      901 aaggtacgca gtaaaaataa atattctgga aagtaagcaa taagcgatta ggagactcaa
      961 attgtggagc gactaaaaca acctttttta aatatggaga aggagttgca agatagttta
     1021 aagcaataac agcgcctaaa gataatccac ataaaataaa aggttccttt atctgattca
     1081 attgtacttc gatgtatttg gttaagtcgt ctaaagtagc agtgtctgtg ctgtttaaat
     1141 gattgaacaa tgaaagactt ttgcaagaat aactattggg tagataagag attacatctt
     1201 tccatgattg ttcgtcttgg cctagaccat gcaaaaaaac aattttcata ttgctctcct
     1261 ttttatagtt atcatataga ctttctttgt actattaaaa tataaacatt catttcttac
     1321 gtcataaaat aaaaaaacag cgcagacaca ttgttaaacc aacatgttgc actgtttaag
     1381 gaagccactt gccgggcttg aaccggcgac ctcttcctta ccatggaagc gctctaccag
     1441 ctgagctaaa gcggcattat cattaataca aataatagga taacgaatat taatgtattt
     1501 gtcaacagaa ttttttcgaa aaaatgtgtt tctctaatag gaaaacagat tttagaaaaa
     1561 ataaaaataa caaaaaatgc gaacggtttc tttgataata taataaaaaa attcaaaaaa
     1621 agtattgcgt tatttagaag aaattgatat tatattcatg tacttgattc cggcatagct
     1681 cagttggtag tagcgcatga ctgttaatca tgatgtcgta ggttcgagtc ctactgccgg
     1741 agtaaataaa gcttatgcaa agaaaaagaa atccaatcac ttgggtttct ttttctttta
     1801 ttattatgat gaatcaagct ttctgttttt gtcacgtatg ttgtaatctt tacgaaagag
     1861 tagagttggc tactcataat caaccatact tcccatcatc gctaaatacg aaataaatca
     1921 gcattcctac accaatcaaa gcacaagctg caccaagaaa agggatgaca ttcccaaagt
     1981 tatctgtatt cataagtatg ccaccaccca caaacaaaaa gccgccagca atcaggtttt
     2041 tcattttatt catctccttt cttacgttat agtatttcct tctttcaatg agtattttga
     2101 aagctatctt attgtatgat gttcttctag gcctcttctt tattatacag gccattttcg
     2161 ttatctcata gaaatattcc tttttatctg aaaactattg tataccgtat gacatttttc
     2221 ttcatgaagt tgtaagtata ttctcattca aatgaaaatt tcatcataga agagattgta
     2281 tttctaaatt cttaagagta aaatacgaag tataacttgg atttggaagg atgattggat
     2341 gaaagctatt acgcctgata tgacaacaaa atttaacaaa cagtttcaag caaatatcaa
     2401 acagcaggca ttgcagcggg cagttgtgaa gaacggaatt actgcttctg ctgaaaatgt
     2461 ttcagcacat gtggagaata caccggtatt ttctatagat ttggctacgg ggaaagtggc
     2521 taatcaaatg caatcggggc gttgctggat gtttgctgca ctgaacacat tccgtcataa
     2581 gatgctgaat caattccatt taaaagagtt tgaattatca caaaattaca cttttttctg
     2641 ggataaatat gaaaaggcaa attatttcta tgaaaacatc attgcaacag gaaaagaggc
     2701 aatcgatagc cggaaagtag ctttcttact cgctactcct caacaagatg gcggccaatg
     2761 ggatatgatc gtttcattat tccaaaaata tggcgttgtg cctaaatcgg tgatgccgga
     2821 aagtgcgaat agttcaaatt ctcgagattt gaataactac ttgaacaaat tactgcgtaa
     2881 agatgcagta gtgttacgga aaatggttgc tcaaggagaa acattagacg ctattgaaga
     2941 aaagaaagaa gaaatgctag aaagcattta taacttctta gctatctcat taggaacacc
     3001 tccaaaagaa ttcgattttg agtaccgcga tgaagaaaag aactatcatc ttgaccgagg
     3061 actgacacca caaatttttt atgataaata catcggtgta aaattagatg attatgttag
     3121 cgtgatcaat gcaccaacaa aagacaaacc attcaatcgt tcttatacag tagagatgct
     3181 aggaaatgtc gttggcggga aagaagtcaa atatctgaat gttgatatgg aaactttcaa
     3241 aaaattagcg attgctcagc ttgaagaagg agaatctgtt tggtttggtt gtgatgtagg
     3301 tcaatcttct actagaacta gtggcatcat ggccttagat gcttattcaa tggatgatct
     3361 atttgatacg gattttacaa tgactaaagc tgaacgttta gattttggag aaagtctgat
     3421 gacccatgcg atggtattga ccggtgttga cttagtagac gggcaatcaa caaaatggaa
     3481 agtcgaaaat agctggggcg aaaaagttgg aaagaatggc ttctttgtta tgagtgatgc
     3541 ctggatggac gaatatacgt accaaatcgt tgtaagaaaa gatttattga cgaaagagca
     3601 attaaatgcg ttcaatgaag aaccaattgt tctatctccg tgggatccaa tgggtgcttt
     3661 agcatagacg agtatttcaa tgaagagtat gtagtaaaga taaaaagagc tggcttaagc
     3721 cagctctttt tatctttaaa gtccattccc tgttttttat ggtccctgtg ctataattct
     3781 aaataaagga taaggattgg aaataatcct tttatcatta aaaatatgat gacgaagtag
     3841 aataaaattg ggagtagggg ggaaagtcat ggatatccaa actgttttat ctgatctgaa
     3901 attaaatggt aaagtgattc cagttgttgg tggcgatgtt aatcagacct atcgtataaa
     3961 aaccgaacat cgtgcttatt ttttaaaaat ccatccgaat gtaaaaaaag gattttttga
     4021 agcagaagta gacggattaa aagaactgtc agcattcgta cgtgtaccgg atacgtatat
     4081 gctaggtgaa acaagtgaag gcgcttattt gttaatggaa tggatcgagc cgggaaaagg
     4141 ggatcaacga gatcttgctg cagctttagc taatctccat cagcaaacag cgccacaatt
     4201 tggttttcgt aaagataact atttgggtac acttgttcag aaaaattctt ttgaagaaga
     4261 ttggtggact tttttcttta aagatcggct tgaatcccag atttctttgg cagaagaaac
     4321 gaatcgatgg aatgtacagc gtcaagaaaa gtatctgcga tttaaagaac gtgtattgaa
     4381 atcggttgaa ccaaaaaaga tcactccacg cctcttgcac ggagacctgt ggagtggtaa
     4441 tgtgttcttt gaccagcaag ggcatccagt ttttgtcgac ccagctgttt cttatgggaa
     4501 tcgggaacaa gatattgcaa tgagccagtt attcggtggt ttccgaccgg aatttttaga
     4561 tgcttatcaa actatatttc cattagaaaa gggatggaaa gaccgactgc cgatttacca
     4621 gttatattat cttttggcac atttgaatat gtttggagaa agttacggtt cccaagtaga
     4681 tcaattacta gaaaattttt aagaggaggg cgtgtttttg gcaaaaaaat ataccaaaaa
     4741 gcatgaagtt tcatattatg agtgtgacat caaccaaacg atgacatttc cttcgatgtt
     4801 aggagtagtt atcaaaacgt ctgaagatca aagcgaccag ttgggaagag gcagtgaatt
     4861 cgtcaatagc tttggactta cttgggtcat cacgaattat tccatggaga ttaatcgtct
     4921 ccctagagtc ggtgaagtaa tctcagtaac gactcaagcc atggagtaca ataagttttt
     4981 ctgttatcgg aacttctgga tccatgatga agatgggaaa gaattagtca aaatagaatc
     5041 tgttttcgta ttgatggatt ttgtgaatcg aaaaatgagc agtgttaatg aagagatcat
     5101 tgctcctttt gagagtgaga agatcaagaa aatcaagcgt caggaaaaaa ttgaaaagat
     5161 tgattcgggc ttcatgttgc catatcgtgt tcgtttttat gatatcgata gtaatcagca
     5221 tgttaataat gcgatgtatt ttaattggat cattgacgta ttaggatatg actttttgac
     5281 tacgcatgtt ccagaaaaag taattattcg atttgataaa gaagtagagt acgggaatga
     5341 gatcgaaagc cattttgaac aaatccctat cgaaaatggt gtcaaaacaa aacatgaaat
     5401 ccgaatgcaa gaacagctgt attgtgaagc aaatattata tggaaaaata aataaaaaag
     5461 aggttgtgac agaagggggc aacttcaaga aataagaaga aatttacgaa aattgtttct
     5521 caaatttttg taaattttcg acttagtttt cgaagaagct atttttgtca cagcctctct
     5581 ttttaagttt agctattaga taatgatgtt tagttttgga taaacgaaat caattcttca
     5641 cccgacaaac catagtttac agcaatcaat agttttaaac gtgctttttg actattaata
     5701 ctgttacaga aaataatccc cattttttct agttcttttc ccccgccttc ataatcataa
     5761 acaggctctg cgattccatt gaaacaacga gaaacaagta ctacagggat tttttggaca
     5821 agaagctttt ccaaagcagc taaggcttgt ggagggagat tccccgcacc taaagcttcg
     5881 attaccaaac cgtctacttt cgtatgggcg atggcttcca ataagtcccc ttgcatccca
     5941 gcatatgctt taacgatcgg gatagtccca tctacagcgg aaatgtccag tcgctttgtt
     6001 tctaaaagtt cctgcaagaa taaaattcga ttcttagtta ctaagccgat gggacccaat
     6061 gtaggtgttc ggaaagtagc aacatttgtg gtatgggtct ttgtcacgta gcgtgcagaa
     6121 tggatctcat cgttcatgac caccaaaacc cccttatcta gcgcttcttc acaacttgcg
     6181 acacgaatcg cactttcaaa attataaagg ccgtcacttc caagttcatt acttgaacgc
     6241 attgccccag tcaaaacaat tggtaatttg ttgccaatcg ttgtatcaag aaaaaaagca
     6301 gtttcttcta atgtatctgt accgtgtgtg atcaccactc cggatatacc tgatgcataa
     6361 gcggacaaga tacgttcttt taataccaac atgtgagaag gcatgatgtg tggtgaggga
     6421 agattgaaga tatcttcaac taataattct acatgcttgg ggattgtgat ttctgcatct
     6481 aataatgggt ttgccacatc aggactaaca ccgcccgtga gcatgttttc tttcatggcg
     6541 atcgttccgc cggtgtgtag tacaagtatt tttttcattt tacagacttc cttacgaata
     6601 attttgcata gccgttaaat cttattgtat actatataaa agagttttgc tatcagtgaa
     6661 gaataacgaa tagcctaact tatcataaaa aagctgacct tattaaaatg gaaaagactc
     6721 aaccttgacc tcctaataca atggagtatc tggttgagtt tcttttacaa gaaagcagcc
     6781 aaggaaatca atcacgaagg tggccggaaa tgatcagaat cggattaaca tcgtttaaag
     6841 aacatgacaa attaactggt aaaaagaata acactcttta tgaatatgca gggtttctac
     6901 ccttagtgga attagatact gcctattatg gaattccccg aaagtcctca gttgagaatt
     6961 ggataagtga agtacctgaa tcatttcgct ttgtagtcaa agtctatcaa ggaatcagcg
     7021 gtcaaggaga ctggaagcct tattatcaga ccgaagaaga gatgattgcg cattttttag
     7081 atgttatgtc gccaatggta gatgctggaa agatgttttg ctttttagtc caattcccct
     7141 catcattcaa atgtacgaaa gaaaatgtcc agtacttgcg caaacttaga aagtggtttg
     7201 agggttatcc tgtttctata gaattgcggg attattcttg gtacagcgat gaatttcttg
     7261 aacgtacaag aaactttatg tctagagccg ctttttcttt agccatcatc gatgagccac
     7321 agttgctgaa tacaacgatt ccttttgatc catttgtcac caatccgaac tttgctcttt
     7381 ttcgattcca tggtaggaat gcgcaaggat ggcaagcaaa tgataaagag tggcgtaaaa
     7441 aaagaacgtt atatcgttat tcagaaaaag aactgcaaga actagcacat gaagtcaaag
     7501 tagttgattc taagacaaaa gaggtaggtg tgatttttaa taataattct ggtggtgatg
     7561 cggctgaaaa tgcattagca ctgcaaaaaa tattaaatat caagccagat ggactcaatc
     7621 caacccaaat ggatctgttt taagggctta ttttattcaa gaaaggggcg aagtctatga
     7681 tcaaagctat tttttttgat attgacggaa cattggtcac caatcgttca aaagcgttgg
     7741 aatcaacaaa acaagcaatt gaatatgctc ggaaaaacgg cattttatgc ggtgtagcaa
     7801 cggggcgcag cccagtaaag atcaaagaaa tcattgatga attggaatta gatatgtatg
     7861 tcgtgtataa tggtcaactg gtttttactg cagatcgcac gattatcgac cacccttttg
     7921 aacaaaaagt attggaacat attgttgaat ttgcagatga gaaccatcga caaatcgttt
     7981 ttggtgcgag aaatcggtta gatggatcaa cgacgatgct attaggacaa tcgattttta
     8041 tcaagcgact agtcagcttt ttaccgcgta aattcccggt acgtctgatg aaaaaaatcc
     8101 tccaggtttt tagccctcac cgacaaaagg atcgttatga aacgttagag atattaaaag
     8161 aaccaattta tcaatgtata ttgctcagtc cggagtcaga acagaaaaag ttagaacatc
     8221 gctttcccga gtgtacgttt cagcgttcaa atacgtatac tgtagatatc atcccaaaag
     8281 gtggttcaaa attactaggc atccaagctt tcgcaaatgc tgtcgaaatt gaaatggaag
     8341 aaattatggc attcggcgat cattacaatg atatcgagat gctgaaaggt gtaggaattg
     8401 gagtggccat ggggaatgct cagatcgaag taaaacatgc tgcagacttt gtgactcaat
     8461 caaatgaaga agatgggata tacgaaggac tgaaacactt cggtctgatt tattagtcaa
     8521 tgaaagaagg aaaaaatcag tatggaagca gagacacctt ttcaaaaagt agaaacattc
     8581 cacaaaactt ttgatccaag aagaccagag atacccacgg cttttacaga aaatgaagct
     8641 catacacgtg ctgcgttcaa aatagaagaa cttgttgaat ttgttgcagc tacttcacct
     8701 aataaagaac aactgcatga agctgttatg ctgctgcacg aagcattaga taaagcagaa
     8761 gaaaaaatac ttggtaaaac acagtgggga agtgatccgc tggttgaaca agtagatgca
     8821 ctgacagata tcctttactt tacttatggt tctttttcat tactaggaat agtgcctgat
     8881 cgaatattcg aaatcgtcca tcaggcaaat atggggaaat tatttccaga tggaaaacct
     8941 cattatgacc ctgtaacaaa taaagtgttg aaacctgaaa actggcagat ggaatatgct
     9001 ccagaaccta aaatcgcggc agaaatccaa cgtcagattc aagaagcgat tgctaagaag
     9061 aaatccgctg atataggcat gtgcacaaat gaaaaagagt gatcagagtt tcactatttt
     9121 tgttatcttt atacgatgga aaaacaaaag attttcgttt aagttagtga atgcatgaaa
     9181 atagtatgct ataatctaga atagatgtct tttgcacgag agacgtatta tttggattta
     9241 tgccaagcag aacgccatct gttgcataaa agatgcatac tgaaaacgga ggaaccataa
     9301 atgggaaata atgttatcat cggaatcgtc attgcaatca ttatagtcgc cattgtcgtc
     9361 tttttggtta gttacttgat gaagaaaaaa aaccaagatc gattggatgc cttagaaaaa
     9421 cgcaaggaag aattatttga cttgccagtg attgaagaag tcgatgatgt taaaaaaatg
     9481 catctggttg ggcaaagcca aaataccttt cgtgaatgga gtcaaaaatg gaatgacata
     9541 tctacttcct cgttcgctga actagaaagt caaattttcg aagtggaaaa cctcaatgaa
     9601 agttttcggt tcttaaaagg aaaaaaagca gttgttgaag cagaagctac aatggaccaa
     9661 atggagaaac aagtgacgga aatccgtgaa ggtctaaagg aattgcggga aacggaagaa
     9721 cgcaactcac tagctgttca gcaggcactt gacgtctatg aagaactgaa agaaaaagtc
     9781 agagaagacg agcatgaata cggaccagct ctttttgaat tgcaaaaaca gatcaaagtg
     9841 atcgaaaaag aatttacgca gtttgtgact ttaaacactt ctggagaccc tgttgaagcc
     9901 cgcgaggttt tggataaagc agaaaaacat acgtatgaag tggaagctct gatgaaaaaa
     9961 attccaccgc tgtatgagga gctccatacc actttccctg aacaacttga agaaatcagt
    10021 gatacttacg agaaattgat ggaagaacaa tatgtattcc cagaagaaga tcttgctgaa
    10081 gatatcgcaa aagtaagtcg aagaattgaa aattcattag ccaatcttga aaaaacagaa
    10141 gttgaaacgg tcgaatttga aaaccgtgaa acagctgatt tgattgattc gttatatgat
    10201 atcttagaac gggaaatgga agctcagaga tatgtaaaaa ctaaccaatc aacgattgca
    10261 gagtatatca aacatacaac aaagaataac cgtcaattat tgattgagct ggatcacaca
    10321 tctcaaagct atacattgaa ccacaatgaa attggccgtg tacgaggttt ccaaaccgaa
    10381 gtggaagaaa tggaacgtca aaatgaacag atgattccac agatccgtca acacgaaatt
    10441 ccttattcag aagtgcgcac gttctataaa acagtcttca aagtcttaga agatatcgaa
    10501 aagcaacaag tagagatcga cgactcatta catgaattga gaaaaggcga aaaagaagcg
    10561 caagaaaaga tcgatacatt cgaattcaaa ttgcgcagtt tgaaacgttt tgtagaaaaa
    10621 caacgtttgc ctggcttgcc gaatgattac ctagaattct tttttgttgc tactgaccgt
    10681 attgaagaac taagtgttgt cttgaataaa attcgagtaa acatggaaga ggtcaatcgt
    10741 ttagttgctc tatgtgaaga agatctagaa ttattagata agaagacaca tgatttagta
    10801 gatgcagcag cattaacgga gcaaatgctc caatatgcaa atcgttatcg tcatacacac
    10861 gaagaagtga gagaagcaat tgataaaagc tactatttat tcaataaaga atatcactat
    10921 caagaagcat tagacgaaat cggtacagca ttagagcgag tagaacctgg tgctttcaaa
    10981 cgcatcgaag atttttattt taatcatcca gacttagtat aaagcaaaaa agttagtaaa
    11041 ccagcaagag caagacggat tattgtcttg ttcttgtctt tttttgtata tttgaaaatt
    11101 gaaacaagtg aaaatttcac ctgctcttga aagcaccttg gacaaccgtt ataatagaaa
    11161 agaatttcaa aaaagagggg tttcttatga tatattttga taacagtgca acaaccccaa
    11221 tctttccgca aagcttagat gcatatgtaa aaaccagtca gcggattatt gggaatccat
    11281 caagcttgca tgatttaggc aatcaagcta accggttgtt gcagcaagca agaaagcaga
    11341 tcgctgattt gatccatgta gaaccagaag aaatctattt tacttcaggc ggaacagaag
    11401 gagataactg ggtattaaaa ggaacgatga tcgaaaaaag agaatatggg aatcatatga
    11461 tcatttcagg agtcgaacat ccggccgtca gcgagacagc agaacaatta aaagaattag
    11521 gaatcgaagt aagtatcgcc ccagtggata aacgcggatt tgtacgtgtc gacgaattga
    11581 aagaattaat aagaaaagag acagtattag tctctgttat ggctgtgaat aatgaagtag
    11641 gatcgattca gcccatccag gaaatcagtg atcttttgga tgattttcct aaaattcatt
    11701 tccatgtaga tgctgttcag gcgattggaa aagtaccatt ctcgcaatgg ttgacagaaa
    11761 gagttgattt tgcaacattt tcagctcata aattccatgg cccacgggga actggtttca
    11821 tttattggaa aaagggtcgt cgtttagcac cattactgac aggtggaggg caagaaagaa
    11881 atcagcgaag tgggacagaa aatgttccag gtattgtggc tatggttaaa gctttacgtt
    11941 tatcattaga gataaaggaa caaaaacctg agcagacaca acgcttaaaa gtagctctaa
    12001 tcaatgcgtt gaagacgtat gagaaagtga cgattttttc agaaggaact gactatgcac
    12061 cgcatatttt atgttttgct ctaaaaggaa ttcgcggcga agttctcgtc catgccttag
    12121 aagaaaaaca aatatttgtt tctactacta gtgcctgctc ctcacgtaaa catatggcaa
    12181 gcagtacatt gcacgcaatg catgtaccaa atgatctggc tacatctgct gttcgaatca
    12241 gcttagatga aaacaattcg cttgcagaag tcgagcaatt tatgattatt ttcaagcagc
    12301 tttataagaa attttctgca atcaattaaa agaggagtgt tcttgtgaaa tacagtgaaa
    12361 ttatggtccg ttatggggaa ctttcgacaa aaggaaagaa tcgaaaaagc tttatcatgc
    12421 aactagcaca aaatgtcaga caagctttga aagactttcc agaaatcaaa atccatgctg
    12481 atcgggaccg gatgcatctt ttattgaatg gcgcagacgg gcagctagtt attccaaaac
    12541 tagcaaaaat atttgggatc caaaatttct ctccaagtat tcgtgtagaa aaagatgtcg
    12601 aagttttgaa acaagctgtt caagacatca tgaaagaaat ttatactggg aaagaaacat
    12661 ttaaaattat cgctaaaaga agcgatcacc aatttgaatt gacaagtaat gaattgaatc
    12721 aaacattagg taatgctgtt tttgatattt tcccgcatat ccaagttcaa atgcgtcaac
    12781 cagatattcc attacgtgta gagattcggc gtgatggcgc ttatctatcg tatgaaacga
    12841 tcaagggagc tggaggattg cccgtaggaa caagcggaaa aggaatgctt atgctttctg
    12901 gggggattga ttctcctgta gcagggtact ttgccatgaa gcggggagtg gaaattgaag
    12961 ctgttcattt tgctagtccg ccgtatacaa gtgaacaagc actgcaaaaa gcaaaagatc
    13021 taacagccaa actagcacct tatgtgggaa cgatccattt tatcgaagtg ccatttaccg
    13081 agattcaaga agaaatcaaa aagtcagtgc cacaaggata ttggatgaca attactcgtc
    13141 gaatgatgtt gcgtttgacc gatgaaattc gccgtattcg tcatggttta gtcattttga
    13201 atggtgaatc attaggtcaa gtggcttcac aaactttgca aagtatggtg gctatcaatg
    13261 aagtaacgaa tacgccaatc attcggcctg tagcgacaat ggataaactt gaaatcattg
    13321 aagtagcaga acagatcgat acatttaatc tttctatcca gccttttgaa gattgctgta
    13381 cgatttttgc tcctccacag ccaaaaacac gccctcaact ggaaaaggtc catcaatatg
    13441 aagagcgttt agcaatagat gaaatgatcc aacgagcact agctggcttg aagatggaag
    13501 agatacaagc agaatcgtct aatgaaaaaa ctgaagaatt ttcagaattg ctataagagg
    13561 ttatgaaaat agtgttttga ccagagtatt agagaaacaa aacgaaaaaa tagctccatg
    13621 tattttaccg tttttgaact aatgtcgaag attagctgat tgaataccat ttatcaagaa
    13681 gttatggaaa agccggttct tttttactaa ctgaaaaata aaattttatt tagagatcaa
    13741 gctacagttg ataaatgata taaaaaagag aatttcccat gaaatagcga ggttgtgaca
    13801 gaagtgggca gcttcaagaa ataagaagga atttacgaaa attgcttttc aaatttttgt
    13861 gaaatttcgg cttatttttc gaagaagtta cttctggaac accgtgtatc agaggttgcg
    13921 aaaaagctgc cctgcatcaa gtaataagaa cagccaaaca aaaatagttc ctcatatttt
    13981 acgtttggtt gagcttatta ccgcagatgc aagcttttga acaccgtttt atttgtctca
    14041 cacccttttc cttcctactt gtaaccttgc tcccgtgtta gaaacatgtt acactaaata
    14101 tgtgaaatta ttaacaagga gcgtcgttat gcgagaaaaa acagatacac tgccaaaagc
    14161 aactgcgaaa agattacctt tatatttacg ctacttgaag atgctggatg actcaggtat
    14221 aagtagaatc aaatcaaatg agttcagcga aatcacccaa attccttctg caacgatccg
    14281 cagagacttc tcgcaattag gcgagctagg cagaagcgga tatggctatg atgtcccttt
    14341 tcttatcgat gtattcaata atatccttaa tactaaagaa gaaaaacgaa tcgcattagt
    14401 aggatatgga aatcttggca aagcattgaa acacaacaat tttagaagaa atgaaaatct
    14461 aaatatcgtg tgcgtctttg ataatgatcc agcactgatc aatcgagtaa ttgatggaga
    14521 aatgatctat ccgattgatc gtttcgcgga gatagccaaa gcaaaaaatg tgacagtagc
    14581 aatctctacg gtaccaagta aatattcaca atctgctatt gatgaaattg tcaaaggaaa
    14641 tgtaaccgct atacttaatt ttgcgcctga cagagtaact gtcccagctt atgtcaatgt
    14701 tcaatacatt gatttgacaa ccgagttgca gacgcttatt tactttgatg agaattactc
    14761 agaagttttt tcttaggaaa atttgagtag gcttattgat cttgcgagaa ctcgtcgtaa
    14821 ttctttcaaa aattttttag tactaaatga agtggttttt tcacgaccac ttgttgacta
    14881 aaaaaaaaaa ccattgtaga atgaagcata acgctgaaca agaggagtaa ctggcacatt
    14941 cattcttaga gagagaacta tctgctgaaa ggttctcaat gacaaccagt gaaggtagct
    15001 tgggagtttc tgtcttgaat ggagtagaga tagacgagtc gtgatcgtta actcacttga
    15061 gaggcaataa tgattgatta ttgcaattta ggtggtaccg cgtaaatcat acgtcctaga
    15121 atacgaaagt atcttaggac gttttttagt ttaaaggagg aaaacagcat gacggaagaa
    15181 aataacctat caacaaaata taatccgcaa gaagttgaag ctggacgtta tcagcattgg
    15241 ttagaacaag atttgtttaa accgagcgga gataaaaaag caaaacctta ttcaatcgta
    15301 atcccgcccc caaatgttac tggaaaactt catttagggc atgcttggga tacgaccttg
    15361 caagatatgc tgattcgtca aaagagaatg caaggatatg atactttatg gctgcctggt
    15421 atggaccatg caggaatcgc gacacaagca aaagtagaag cgaagcttag agagcaaggg
    15481 atttctcgtt atgatctagg tcgtgaaaag ttcatcgatc aagtgtggga atggaaagaa
    15541 gagtatgcga gccacatccg cgaacagtgg gctaaaatgg gcttatcttt agattacagt
    15601 agggaacgtt ttacattaga tgatggatta tctgaagcag tacgtaaagt ttttgttacc
    15661 ttatacgaaa aaggtttgat ttatcgtggt gaatatatca tcaactggga tcctcaagca
    15721 cgaacagctc tatctgatat cgaagttatt cataaagata tcgaaggcgc cttttatcat
    15781 atgagctatg aactagcaga tggatcaggc gtagtagaaa ttgcgacaac ccgtccagaa
    15841 acgatgttgg gagatacggc gattgctgtt catccagaag acgagcgtta tcaagcgctc
    15901 atcggcaaaa aagtgattct acctttagtc aataaacaaa tcccaatcat tgcagatgaa
    15961 tatgtagata tggaattcgg gacaggtgta gtaaaaatca ctccagcaca tgatccaaac
    16021 gactttgagg taggtaatcg tcatgatctt ccacgcgtaa atgttatgga tgatgatggt
    16081 acgatgaatg aactagcagg aaaatatgct ggaatggaac gttttgctgc tcgtaaagca
    16141 atcgtgcaag atctgaaaga aatcggtcga ttgattaaaa tcgatacgat gatccacagt
    16201 gtgggtcatt ccgagcggac aggtgtcgtt gttgaacctc ggctgtctac tcaatggttt
    16261 gtaaaaatgg cgccgttagc gaaaaaagcc attgataacc aagaaacaga tcaagcagtg
    16321 gaattcttcc ctccaagatt caatcaaacg tttttacgtt ggatggaaaa tgtccatgat
    16381 tgggtaatct cacgacaatt atggtgggga catcaaattc ctgcatggta tcacaaagaa
    16441 acaggtgaaa tgtatgtagg gatggaagca ccagcggata gtgaaaactg ggtacaagat
    16501 cctgatgttt tagacacttg gtttagttca gctttgtggc ctttctcaac aatgggctgg
    16561 ccagatacgg aaagcgaaga ttataagcga tacttcccta ctagcacttt agtaaccggt
    16621 tatgacatca ttttcttctg ggtaagcaga atgattttcc aaagcttgga atttactggc
    16681 gaacgtccat ttgagaatgt cttgattcat ggattgattc gtgacgaaca agggcggaag
    16741 atgagtaaat cattaggtaa tggaatcgat ccgatggaag taatcgaaaa gtatggagca
    16801 gatgctctcc gctggttctt atcgaatggt tctgcaccag gacaagatgt ccgcttcagc
    16861 tatgaaaaaa tggatgcttc ttggaacttt atcaacaaaa tctggaatgc ttcacgtttc
    16921 gttatcatga atatcgaagg aatgaccgta gaagagatcg atttatctgg agaaaaatca
    16981 gtggctgacc ggtggatcct tactcgtttg aatgaaacga tcgaacgagt aactgagcta
    17041 tttgatcgtt ttgaatttgg tgaagcaggt cgacaactgt ataactttat ctgggatgat
    17101 ttttgtgact ggtacatcga aatgagtaaa gaagtacttt atggagatga tgctgtttca
    17161 aaacaaacca cccgtagcat cttagtccat acacttgatc agatcctacg tttattgcat
    17221 ccaatcatgc cattcgttac agaagaaata tgggaacata ttcctcatca gggaaattct
    17281 ctagtagtgg cagaatatcc tgttgtacgt ccagagtttg atgatgaaac agcttctaaa
    17341 gggatggaag tattgaaaga attgattcga gccgttcgaa atattcgttc agaagtgaat
    17401 acaccattgt ctaaaccaat tacgttgcta attaaaacaa acgatgctaa aatcgatcaa
    17461 tttttagttg aaaatacaag ctatatcgaa cgcttctgta atcccgaaga gttgacgata
    17521 tcaagtgaga tcactgcgcc agatctagcg atgtcagctg ttctgacagg tgcagaaatc
    17581 ttcttgccgt tagcaggatt gatcaatatt gaagaagaaa tcaaacgatt agaaaaagaa
    17641 ctggaaaagt ggacaagcga agtaaaacgt gtccaaggaa aactttctaa tgaacgtttt
    17701 gtttctaacg cgccggaaga agtagtagag gcagagcgtg caaaagaaaa agattattta
    17761 gagaagcaaa cggctgtcaa agaacgaatc gaaagtttgc gtactattca ataagaatag
    17821 aaaaagagag tgtgaaatca gctagctatt actaaaagct agctgattga acatcgttac
    17881 aggaaagagt ttgagcctca ctcttagctt cgattcataa ggagatgtga cataaatttt
    17941 gtcgcatctc ttttttagtc tactcttatt atgtaggaga aggagggagg tggatcatgt
    18001 atcaagagtc aataaagtag ttgataaaat cgttcctctc tctgtttctt ttctctttgt
    18061 catactttta tttttcttat gtgttctatt tgttataata aaagagaaat gggggaattg
    18121 ttgatgacga ttgaagaagc aatagaatgg atccatagtc gattaccatt tggttcacgt
    18181 cctggccttg accgagtcga agctttatta gaagtggtag ggcatccaga gagaaaagta
    18241 aaaacgatcc atatcgctgg aacaaacgga aaaggttcta ctgtagctta tttgagaagc
    18301 ctattagaag aggctgggct gacagtaggt acatttactt caccttatat cgaaacgttc
    18361 aatgaacgga tcgcaatcaa tggcaaaagc attccagaca atgatttgat ccagcttgta
    18421 aaaaaatatc agccactgat caaacaactt gatcaatttg aagcagtagc tggtattact
    18481 gaattcgaga cattaacagc aatggcattt gattattttt tgatgaagaa agtggacgta
    18541 gcgattatcg aagttggctt aggcggctta ttggattcta ccaatgtagc tgtaccaatg
    18601 ctgacgggaa taacaacgat tggacttgat cataccgaaa tacttggaga tacaattgaa
    18661 gaaatcgctg cacaaaaagc tggaatcatc aaacaaggcg ttccagtagt aacaggaaat
    18721 attgccccag aagcttttac tgtcatccaa caaacagcta aagcaaaaaa tgcaccgctt
    18781 tatgtatacg gggaaaatta taaaataaac tatctgcatc ctgatgagat gtggggagaa
    18841 gtatttgaat tttttaatga aataggaaag atccctcaat taaccactcc gcttttaggg
    18901 caacatcaag ctgaaaatgc aggagtagcc atcgaattgt attttgttta ctgtcaattg
    18961 gaaaagctgc ctttccgaga aaaagatgtt ttgaagggat tgaagaaatc tcgatggcca
    19021 ggaagaatgg agcgtttgag taacgagcca ttagttgttt tagatggtgc ccataatacg
    19081 catgcaatga accggcttgt tgagaatttg aaaaaagaat tcaaaggata tcaaatcaac
    19141 attttgtttt ccgccttacg aactaaaaat gttagagaaa tgctagaacg attgcagcaa
    19201 gtaccaaatg tccatattta tttgacgacc tttgaacatc caaaagccat cgaattaagt
    19261 gaagtatcag atttagcaag tgagagagta tcaatcgttt cattgtggca attcggatta
    19321 gcagatatat tggaaaagat gacaaatgaa gacgtattag ttgtgaccgg ttcactttat
    19381 ttcatttcag aagttcgcca tttattaata caattaggag gagatcatga agtataatgc
    19441 agtgattttt gacatggatg gtttgctgtt cgacacagag ttagtgtatt acgaagccac
    19501 acaagtagta gcagacaaga tgggttttcc ttatgataaa gacctgtatt taaaattctt
    19561 aggtgtttca gatgaagaag tatgggcgaa ttatcatatg attttctcgg aatttggcaa
    19621 aacaagtgta caaagattca tagatgattc ataccaggaa acgcttgaac gtttttcgca
    19681 aggagcggta caaatgaagc ccggtgtgtt ggaactcctc tcttttttag aagaacatca
    19741 gattcccaaa gttgtcgctt ccagtaacca acgagcagtc attgaacttt tattgaagaa
    19801 gaacaatctg tttgaacgat ttgagacgat tgtttctgca gaaaatgttc aacgagcaaa
    19861 accagaccca gaaattttct tgttagctaa tcagaagcta ggtacagcga agaaagaaac
    19921 attgatttta gaagattcac aaaatggtat tttagcagct tctgcggctg agatcccggt
    19981 agtcatggta ccagatctgc ttccaccatc ccaagaattg atcaaaaaaa cagctggggt
    20041 tgtttcttct ttacatgaaa tccctgcatt gttaaaataa aaatccatct cttttcgtat
    20101 cttattttag ataagataga aaggagatgt ttttttggga aaacgattga tcaaagaagt
    20161 acctactagc tctttaccaa gggaacgtat ggaaatttat ggcgcggaag ctttatcgga
    20221 tcaggagctt ttggcaatct tactgcgtac cggtcaacac ccttatagtg tgatgtcgat
    20281 tgctggaaat ctgttaaaaa cgtttggagg actggcctct ttacgacagg ctactttgca
    20341 tgagttagaa gagattcgag ggataggacg cgtgaaagca atcgaaatca aagccttgat
    20401 cgaattaggt cgacgaattc agacggatca tgaaagagcg gctccaccgg ttcgtaccag
    20461 ctacgaattg gcccagcaat tgattctgga aatgaaagat cacaaacaag aacatttggt
    20521 ttgtatttat ttggacacga agaatcaagt gatcttaaaa aaaacagtgt tcatcggttc
    20581 gctgaatcag tcagtcgctc atcctagaga aattttccat tatgctgtac gttattgtgc
    20641 agcaaggatc gttttagcgc ataatcatcc ttctggtaat gttattccat cgcagcagga
    20701 tatgaatttt accaaaagga tacaaaagtg tggagaaatg atggggatca ctgtactgga
    20761 ccacttgatc atcggacgca aacgatattt tagtttgaga gaagaaggaa tgatggaaga
    20821 gaagtaagtt gctttcttgc aaaaaaaatg aagcaagtgt acaattatat tgtaattttg
    20881 tttgggaata gaagttgaaa catctgttgc acctctatcg tacacgagca atgttacaat
    20941 ttaaattagt gcttttggca cgaggaggat attattatgg aaaacggaac agtaaaatgg
    21001 ttcaacgctg aaaaaggatt tggatttatc tcacgtgaag atggaagcga cgtattcgtt
    21061 cacttctcag ctatccaagg tgacggattc aaaacattag aagaaggtca agcagtgact
    21121 ttcgacgttg aagaatcaga ccgcggccca caagctgcaa acgttgtaaa agcttaattt
    21181 tatctgtaaa tcaaattgat ggtagacatc aatttttacg agagaacaaa gcgagtaaca
    21241 aaaatacctg ccacaagaga caatttctct tgtggcaggt atttttttgt atgaaaaagt
    21301 aaataaattt aagaggctat gaaagagcca ccttgtatca aggaataaga acaaacaaaa
    21361 atggcttctc atgtttttca tttgttttct cttatattca ggacaaggtg ctgatttcat
    21421 aacctcttat ttattcttca tctggtgtca ttaccattgg caaaatcatt ggatgtcttt
    21481 ctgtacgttc gaataagaaa ggctgaagcg cgccagtcat cgcttctttc aatttatatt
    21541 ctgaacagtc aggtccattc aaacattctc ttaaagcgtg gaataagatt cgctgagctt
    21601 cattgatcat ttctcctgat tctcgcatgt agacaaatcc acgagagaga atatctggac
    21661 cagccaagat ttcttttttc ttgatatcca ctgtcgcgac agctaataca agaccttctt
    21721 ctgaaagcag gtgacggtca cgtaaaacga cattaccaat atcaccgatc ccgctaccat
    21781 cgatatacac atctccagcc acaaaatgcc cagcaggacg cgcagaatcg ctagttaacg
    21841 ctaaaacatc gccattttcc atgatgaagc agttttctgc aggaacacct acatcttgtg
    21901 ctagagaagc atgtactttc aacatgcgga attctccgtg gacaggaata aaatattttg
    21961 gcttcatcaa acgaagcatt aatttttgtt cttcttgtcc accgtgaccg gaagtatgga
    22021 tgttattgat ttttccgtga atcacttctg caccagcttc agacagcaaa ttgatcaaat
    22081 gattgacact tgttgtatta ccaggaatag gtgaacttga aaagatcact gtatcgtctg
    22141 gctggatttg gatttgacgg tgagtaccat tcgcgatgcg gctcaacgcg gccatcgctt
    22201 ctccttgaga acctgtacat aggatcatcg tttcattggc aggcaagcga ttgatttcgt
    22261 gtgcatctac aaatgtgccg tctggaactt tgatatatcc taaacgttga ccgttgacga
    22321 tggcattttc catgcttcgt ccgaaaacag cgattttacg accagttgcc acagcggcat
    22381 ctgctgcttg ctgcaaacgg aagatgttag aagcaaagct ggcaaaaatg atacgtcctt
    22441 cgatttttga aaagatcttc aaaatagaat gcccaatcgt tttttctgat ttagtaaatg
    22501 ttggaatctc agcatttgta ctatcagata aaaggcacaa gactccttct tccccgatac
    22561 gagccatttt atgcaagttt gctggttcgc caacaggagt gaaatcgaat ttgaagtctc
    22621 cagtcgctac gatatttcca gaaggtgttt tcaccacgat ccctaatgca tctgggatac
    22681 tatgggtcgt tctgaaaaag ctgacagaag tctttctaaa acggatgatc gtatcttcat
    22741 tgatctcatg gagctctgca tctcgaagca agccatgctc atctaatttg tttgtgatca
    22801 acgctaatgc gagaggacca gcatagatag gaatatttgc ttgtttcagc aagtagggta
    22861 ttccgccgat gtggtcttcg tgcccgtgag taatcaccaa ggcttttact ttgtgtaagt
    22921 tttgtatgat gtagctgtag tcgggaatga catagtcaat tccaagtaaa tcgtcttccg
    22981 ggaatttgat cccggcatca atcaaaatga tttcatcttg gaattgtacc ccatacgtat
    23041 ttttcccgat ttcacctaat ccaccaatag caaagacgcc tgtctcgtta tttttgatgg
    23101 aaagtttcat attaaaactc cactaatgag aaatcagcat tttctttttc gtactctaga
    23161 tgacttcctt ctagaagttg aacgaattca atattgtatg gggtattttc ttccacacgt
    23221 tggcgagcgt ctacatcgct ttttgcctca atgtaaagag attttgtttc ttcccgttta
    23281 gggttgcgta cttttgtttc ttgataataa actttataga tcattgtttt gtctccttta
    23341 tctgcgtaaa gcagtgattt agctagttga tttttttaga caacacaaaa cgaggggaca
    23401 agccacctgg tttttcatat gctttgacta gaatactgga ttcgagtcaa agagacaagc
    23461 ctcgtttttg cttatctgtt cggatatttt ttcaaccgta ccttctgtat aaaaaatata
    23521 caacaattaa ttgttattct agcataaaac agcaaataag tatagaaatc aactagattg
    23581 aaagaaaaaa tcaatgttta tcatcccgct ataatcataa tgactttttt atgagagaag
    23641 tgttctatta ataggctcgt tgtgctatca tttttagtaa tgaaaatgta acgaaagatt
    23701 aaaaggagat gagaaagtga aactaatgtg gcattatacc atgcgttata agaaattctt
    23761 gtttttcaat ttcatatgcg tatttggttt tattttgatt gaattaggac ttcctacgat
    23821 tttagcacgt atgatcgatg taggaatccg caatgatgat tttgattatg tgaagcaaca
    23881 agggatattt atgatcgtta ttactgtaat cggtattatt ttgaatatct tgttaggtta
    23941 ttttggttcg aggattacga ctaatatcgt agcagatatt cgagatgatt tgttcgaaaa
    24001 gatccaaagt tattcgcatc aggaatacga aaatctaggc gtatcttcat tgatcactcg
    24061 tacaacaaac gatgcttatc agatcatgtt gttcctgcaa aatattttac gtatcggttt
    24121 tatggcacca atgatgttca ttgtcagttt gtacatggtc atgcgtacaa gtgtgacact
    24181 cagtttgtat gtagtaggtg cattaccttt actattattg gcagtcgtag cgattgctaa
    24241 ggtgtctgaa ccgttatcta aaaagcaaca aaaaaactta gataaaatca acagtatctt
    24301 gcgggaaaat ctttcaggat tgcgtgtgat tcgtgcattc gtcaatgaaa agtttgaaga
    24361 aaaacgtttt gctgtagtca atgagaatta tgcttctagt tcaaaaagct tattccgttt
    24421 gatggctgtt gcacaaccgg gtttttattt cttatttaat atcgtaatgg tattgatcat
    24481 ctggagcggg gcagtgcaaa tcgatgcagg cgagcttcgt gtaggagatt tgattgcgtt
    24541 tatcgagtat atattccatg ccttgttctc attcatgtta tttgctagtg tgttcatgat
    24601 gtatccaaga gcagctgttt cagctggacg tatccaagaa gccctagatg ccaaaccttc
    24661 gattgtagaa gatccaaatg gtatatctga tacaaaaact aaagggtata tcgaatttca
    24721 aaatgtaaca tttgcttatc caggccattc gcaagagcca gtgatacgaa atgtcagttt
    24781 tacagcctct ccaggagaga ccgttgcttt tattggaagt accggtagcg gaaaatctac
    24841 gttgatccaa ttgatccctc gcttttatga tgtgagtgaa ggaaagatct tgatcgatgg
    24901 agtagacgtg agagattatc ggctaagcaa gttgcgagat aagattgggt ttattccgca
    24961 aaaagcgctg ctatttactg gaacgattgc agataatttg cgatacggga aagaagatgc
    25021 tacgcaagaa gaaatggaac gtgcagctga gattgctcaa gcttcagaat tcatttctcg
    25081 aaaaccagat ggatttaatg aacatttatc agaaggtggt tccaattttt caggtggaca
    25141 aaaacaacga ttggcaatag ccagagccat catacgccgt ccggaaatct atatttttga
    25201 tgacagcttt tctgcattag attatcaaac ggatgcgaag ttacgtgctc gtctgaaaaa
    25261 agaaacgaca gaatctactg tattgatcgt agcacaacgt gtgggaacga tcatgcatgc
    25321 agataagatc atcgtattaa atgaaggaga agtcgtcggt atggggacgc atcgggagtt
    25381 gttggaaaaa tgcccgattt attatgatat tgccgcttct caattatcaa aggaggaatt
    25441 agcatgaaaa aaaccttttc ttccttaaaa cgtttagctc gatatatcag accgtatcgt
    25501 gagacttttc ttttagtgat cctatttaca gttctgacag tggctttcaa cgtggctttg
    25561 ccatatgtta caggacttcc tactacagaa atcagccgta atattgccaa tggcgaatca
    25621 atcaattttt cttatatatt caaatgtctc atttggatca cagttgttgg aatagggtat
    25681 tgtatttcgc aattactttc tggtgttttg atgacaaatg tcgttcaaag tgccatgcat
    25741 gatttgagaa gagacataga agaaaaaatc aatcgtcttc cggtttcata tttcgataaa
    25801 aaccagcaag gaaatatttt gtctcgtgtg acgaatgatg tagatgcagt cagcggtgct
    25861 ttacaacaag cttttattgg tatcgtaaat gcgatattgg gaattacgtt ggctgcagca
    25921 atgatgtttt atatccagcc gatgatggcg ctgatctcta tgatcatgat tccaacatcg
    25981 atctggatct caaaacgagt gatcaatgct tcgcagaaat attttcaaag catgcagaat
    26041 tctcttggtg agctaaacgg ctacgtccaa gaaaatatga caggttttag tgtattgaaa
    26101 gtatatggac gcgaaaaaga aacattggaa ggattcaaaa aagttaatca cagcttgaaa
    26161 tactttgggt ttcgtgcagc attcatttct ggcttgatga tgcctctagt tcaattaact
    26221 gcctatgcta cttatattgg tatggctgtt ctaggaagct tttatgttat tactggggcg
    26281 atcgttgtcg gtcaactaca agcattcatc caatatattt ggcaaatcag tcagccaatg
    26341 gggaacgtga cacaattgtc ttcagttttg caaagtgcat cagcggcaac gaaacgtgta
    26401 ttcgagattt tagatgagcc agaagaaaaa gaaaacaaag tagatgcttc actgccagaa
    26461 acgattttag gagatgtgac attcgatcat gtcgattttg catatgatcc gaagaaacca
    26521 ttaatccaag atttgaattt tgaagtgaaa gctggtcaaa ccgtagctgt ggtcggtccg
    26581 accggtgccg gcaagacgac attgatcaat ctattgatgc gtttttatga cgtagacaaa
    26641 ggagcaataa ggattgatgg aatcgacacc aaatcaatga gtcgcagtga tgtgcgttcg
    26701 ctatttggta tggtcttgca agatgcatgg ctttatcaag gaacgattgc agataatatc
    26761 cgcttcggaa agcttgatgc gacagattat gaagtagttg atgctgcgaa aacagcaaac
    26821 gtagatcatt ttatccgaac gatgccagat ggatatgata tggccatcaa ttctgaggga
    26881 gacaatgtgt ctttaggaca aaaacagttg ctgacgattg cccgagcagt ggtctccgat
    26941 cctaaaatct tgattttaga tgaagcaaca agttcagtag acacccgttt agaagcgttg
    27001 attcaaaaag caatggatcg cgtgatggag ggacggacaa gtttcgtcat cgctcaccgt
    27061 ttatcgacaa tccgtgatgc agatctgatt ctagtgatgg atcaaggtca gatcattgaa
    27121 aaaggaacgc atgagagttt attggcacaa ggtggatttt atgaaaaact gtataacagc
    27181 caatttgctg aggaagcaga ataagtcata taagaataaa acagtttaaa acttattttt
    27241 tgttctctat tcttgataat ggtaaagtaa agttatcaag aaaagtgagg acacggagat
    27301 ggaacagttt ttaaatgaaa aaattactga agccaaaaga gaagttgatc gtttaacgca
    27361 cgtctgtcag acgaagcctt ttgattcagc tgattttttt gaaaatgagt ttcaaatcga
    27421 acgcttggca gcacaaatag aagtgtacga attaatttta aaaaaagtaa tagaagaaaa
    27481 tatagatgta caataaaaac aggtaaaacg tcagttacca gatactgtaa atagacatct
    27541 ggcctgagca ggttttacct gttttttttc ttatgaaata aatatatgct atgatacctt
    27601 tattcaatag gattagtttc tacaaaaaat gaaaggagaa aaataaatat ggaacggttt
    27661 atagcatcaa atgccacagt gattggtgat gtgacattgt cagaagatgt gacgatctgg
    27721 tatcaagctg ttttacgcgg ggacagtaat tggataaaaa taggacaaag aacgaatatc
    27781 caagatggta caatcatcca tgtcgatcat gatgcacctg tagatattgc ggagaatgtg
    27841 acggtaggac atcagtgcat gctacatggc tgtacaatcg aaaaaggggc gctgatcggg
    27901 atggggacca cgatattgaa tcatgcggtt attggtgaga atagtttgat tggtgctgga
    27961 tcattagtaa cagaaggaaa agttattcct cctaatgtct tggcttttgg tcgcccagct
    28021 aaagtgatcc gtcctttgac aaaagaagaa atacaaaaaa acaaagaaaa catccagcat
    28081 tatgtcgaga taggtcggat gcatgcgcaa ggaaaattca aggagcaaag ataggcagta
    28141 gcatccataa aataaaaaag gatggtcagt ttgagttgac catccttttt tatttggttt
    28201 agataagaga gcttaaaaaa gcttcctttg aaacagatta atttaatgaa gaactgtttt
    28261 ccatgacttc atcgatcaat ccatatgctt ttgcttgttc agctgtcata tagttgtcac
    28321 gatctgtatc tttttcaatc acttcaagcg gttgtccagt gcgttcagct aaaattttgt
    28381 ttaagcgttc gcgtgtttgc aaaatatggc gtgccgcaat ttcgatttca gttgcttgcc
    28441 cttgagcgcc gccaagaggt tgatggatca tgatctcagc atttggtaaa gcaaatcgtt
    28501 taccttttgt accagctgtc agcaagaagc ttcccattga agcagccata cccataacaa
    28561 ttgtttggac atctgctttg acaaagttca ttgtgtcgta aatagccata cctgctgtaa
    28621 ctgaaccacc aggagaattg atataaagat agatatcttt ttcagaatct tgagcgtcta
    28681 agaaaagcaa ttgggcgatg atcgaattag caagatcatc tgttacttgg ccgcttaaca
    28741 tgatgatacg gtctttcaat aaacgtgagt agatatcgta agctctttca cctcgtgaag
    28801 attgttcaat gactgtagga attaaattca taatagagtt cctccttgat ttcgtttaga
    28861 aatagtgtac cataatttag tttctaatac ctaaaatgta gtatacattt ttggtcaaaa
    28921 aaggtcaaat aaaaaactta ggcaaattag tcgcataaac ccgctttatg gtatgataag
    28981 cagagaaaca aaacaaggag gaacaacaga ttgatagttg gtattactgg ccttatcgga
    29041 gtgctgacag gtgctgtagt tgtctatatc ggcatgatac tgcaaatgcg tcacttggaa
    29101 aataaagaac agcgtagacg tgaattggaa ttgaaagtca aagaaatcga gacgctgaat
    29161 caattaaata aaaagatcaa cgagatcttg caaaaacgga caacgctgat ggaagaatat
    29221 gtcagctttg atgcatttga tgattgttat atcacgattg acgattttgc gtatctccaa
    29281 tcattttcag cgcaaaatag tttttatctg ccaaattata ttttagacga gctatttaag
    29341 aatatctccc atcgaaaagt gattttatct ccagatgaaa caatgaagat tggtggatat
    29401 gcttataaag gcggacgcgt gattttagag aattttacgg atagtctgac tgaaatgatc
    29461 aatgaaaaaa aagctcagtt gaagactatg acgcgccagc cgattggttt cttctcgaaa
    29521 gatgatgttt ggagctgata ttttgaagca ttgccgttgc acatgagagc gtggtaatgc
    29581 tttctttttt tcttaatgat acaatagaac tgaacggagt gaagaaagat gttacaaatc
    29641 tatgcccatc gcggaagcag cggcacccac ccagaaaata cgcttcctgc atttgcagaa
    29701 gctgtacgag taggtgcaga tggtatcgaa ctagatgtcc atctaagcaa agatggttat
    29761 ttgatcgtta tgcacgacga agaagtggac cggacgacta acggtaaagg gctgattcga
    29821 gaaaaaacat tggaagaact caaaaaattg aatgcagggg gcaaattcag caaagaattt
    29881 ccagcagcta aagttcctga attgagagaa gtgttaggac tgctcctcca aaaaaattac
    29941 cgagggatgc taatgattga aattaaaact gatcagtatg aatatcccgg tatcgaagaa
    30001 aaattagccg aaacattaaa aagtagagat tggccttttc aacatgcata ttgcagcttt
    30061 catttggatt ctttggaaaa aatcgcatta ctggaaccgg agatacagct ggacttattg
    30121 atgagtactt ctgataaaaa gatccaacta gcagcagaaa ccccttatat agaaggagta
    30181 catccaaaaa atacttggtt gttcgaacat ccagtccagg cagctgattt tccaaaagca
    30241 attcgtgcat ggacgattaa cgatgaagaa gaaatggcca aatgtcaaga actcaaaata
    30301 gatggaataa taactgattt tccggagaaa gctcttcggt ggaaacaatc aacgaaaagt
    30361 aggtaaaata tggaaaaagt attagtgatc gtcggtccga cagcagtcgg taaaacagcg
    30421 ctaagtgtgg aactcgcaca actatttgga ggagagatca tcagtggtga ttcattgcaa
    30481 atctataaaa atctggatat cggtacagca aaaatcaaag aagaagagat gaataatgtt
    30541 ccgcatcatt tgattgatgt gatcgaacct actcaacgtt actcagccgc tgattttcag
    30601 cattcaggtc gacaattgat taccgagatt gcgaaccgag ggcacctacc tatcatagct
    30661 ggtggtacgg gtctctatat ccaatccctt ctatatgatt atcagttagg agcgacagaa
    30721 gaagcgaatc ctgagattag aaaaaagtat gaaacgttag ctgaaacaat tggttcccaa
    30781 gcattatgga atcagttgaa agaaaaagac ccggcagctg ctgagaaaat ccactggaac
    30841 aatcaacgca aagtgataag agctctggaa gttttagaga cgacaggaca tagtatcacg
    30901 gcacctaaag aagagccaaa gcaattgtat gattacctca tgattggatt agatacgaag
    30961 cgtagtattc tttatgaacg aatcaatcaa agagtcgatt tgatgctagc agaaggttta
    31021 gtagcagaag cgcgtaaggt gtatgagctt ggagaagtcc aggccagtca aggtattgga
    31081 tataaagaat ttttccctta ttttgaaggg aaagaaacat tggaagaagc aacagaacaa
    31141 gtcaaactac attcgagaag atacgcgaaa cgtcagttga cgtggtttcg taaccgtttg
    31201 gatgcacagt ggtttgatct tataagtgag ccaaatcaaa aaagtcagat tgagcaaaca
    31261 atcaaaaaat ggctggaggc ggaataaaat ggaagaaaaa gtgatcatcg taggggtaga
    31321 aaccgaagca aaccagcgtt acttttcaga gtcaatggaa gagctagttc agctgacgaa
    31381 taccgcatca ggagaagtcg tattcacaat tacacaaaag agaccacaag tggatcggca
    31441 aacgattatc ggtaaaggga aattacaaga attagttcaa caagcggatg cgcatgaagc
    31501 ggatttgatc atctttaatc atgagctaac tccgagacag agccaactga ttaccgatgc
    31561 tgttggtctt ccggtaattg atcgcgtgca gcttatctta gatatttttg cgatgcgtgc
    31621 tcgttcgaaa gaagggaagc tgcaggttga acttgctcag ttagaatacc tgctgcctcg
    31681 tttagtaggg caagggaaaa cattatctcg tcttggcggt gggatcggaa caagagggcc
    31741 aggtgaaaca aagttagaaa cagaccgccg acatatacgg aataaaattt ttgctgttaa
    31801 gaaagaattg aaagaagtag aagctcatcg agagcgcaat cgccaaaaaa gaaaaaatag
    31861 cgagattttt cagattggac ttattggcta cacgaatgcc gggaagtcaa ctatcttgaa
    31921 tctattgaca caagcggata cttattcgaa agatcaattg tttgcaacgt tagatccatt
    31981 gactaagaga tggcgttttg ctgaaggatt tgagattact gtaacggata ccgtcgggtt
    32041 catccaagac ctgcctacgc aactgatcga tgctttccat tctacattag aagaaagtca
    32101 aaatatggat cttttgctac atgtagtcga tgctagttct ccagatcgta ttttacagga
    32161 gcagactgtc ttaaaattga tggatgaact gaatatgaaa gaaatgccga tactgactgt
    32221 ttacaataag gcagaccaga tcgacccagc gatgttcacg cctacgctat tcccaaatgt
    32281 attgatttct actcagacga aagaaggtaa gatggcgttg atcgaagcaa tcaaacgtca
    32341 gctgatggaa ctaatgaccc cttatacact ttctgtgcca agcaacgaag gacagaaatt
    32401 aagcgagttg agaagacaaa caatggtttt ggacgaagcg tacatggaag aaacaaacga
    32461 atatgaagtt aaagggtttg caaaaaccaa ttcaaaatgg ttaagaaaaa accaataaaa
    32521 ttttattttt ttaa
//
LOCUS       DACDLM010000029        30811 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.029, whole genome shotgun sequence.
ACCESSION   DACDLM010000029 DACDLM010000000
VERSION     DACDLM010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30811
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.029"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(7..3660)
                     /gene="rpoC"
                     /locus_tag="IV356_001393"
     CDS             complement(7..3660)
                     /gene="rpoC"
                     /locus_tag="IV356_001393"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HAP9015087.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(3739..7356)
                     /gene="rpoB"
                     /locus_tag="IV356_001394"
     CDS             complement(3739..7356)
                     /gene="rpoB"
                     /locus_tag="IV356_001394"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAP9015088.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            8084..9052
                     /locus_tag="IV356_001395"
     CDS             8084..9052
                     /locus_tag="IV356_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP9015089.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            9070..9975
                     /locus_tag="IV356_001396"
     CDS             9070..9975
                     /locus_tag="IV356_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9015090.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            9972..10778
                     /locus_tag="IV356_001397"
     CDS             9972..10778
                     /locus_tag="IV356_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP9015091.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            10935..11903
                     /locus_tag="IV356_001398"
     CDS             10935..11903
                     /locus_tag="IV356_001398"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HAP9015092.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(12220..12744)
                     /locus_tag="IV356_001399"
     CDS             complement(12220..12744)
                     /locus_tag="IV356_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinB family protein"
                     /protein_id="HAP9015093.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            13031..14842
                     /gene="scm"
                     /locus_tag="IV356_001400"
     CDS             13031..14842
                     /gene="scm"
                     /locus_tag="IV356_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAP9015094.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDT
                     SASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTS
                     ASSDSTDTSTTTSDSTDTSASSDSTDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSS
                     TTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKR
                     ALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
     gene            complement(14997..15983)
                     /locus_tag="IV356_001401"
     CDS             complement(14997..15983)
                     /locus_tag="IV356_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAP9015095.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(16006..16572)
                     /locus_tag="IV356_001402"
     CDS             complement(16006..16572)
                     /locus_tag="IV356_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HAP9015096.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(16586..17002)
                     /locus_tag="IV356_001403"
     CDS             complement(16586..17002)
                     /locus_tag="IV356_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HAP9015097.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(17459..19393)
                     /locus_tag="IV356_001404"
     CDS             complement(17459..19393)
                     /locus_tag="IV356_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP9015098.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            19695..20630
                     /locus_tag="IV356_001405"
     CDS             19695..20630
                     /locus_tag="IV356_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HAP9015099.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            20720..21823
                     /locus_tag="IV356_001406"
     CDS             20720..21823
                     /locus_tag="IV356_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HAP9015100.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            21836..22789
                     /gene="menA"
                     /locus_tag="IV356_001407"
     CDS             21836..22789
                     /gene="menA"
                     /locus_tag="IV356_001407"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HAP9015101.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFDLVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(23603..24949)
                     /gene="gor"
                     /locus_tag="IV356_001408"
     CDS             complement(23603..24949)
                     /gene="gor"
                     /locus_tag="IV356_001408"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HAP9015102.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(25083..26324)
                     /locus_tag="IV356_001409"
     CDS             complement(25083..26324)
                     /locus_tag="IV356_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAP9015103.1"
                     /translation="MTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAYGLRS
                     RAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISAVIVS
                     DPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVAEIRK
                     NTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFGQERN
                     SLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNVYKAA
                     VDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVYKFVG
                     EVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRAPNPM
                     MILTMPVAQPVKPGDMIRKRK"
     gene            complement(26342..27265)
                     /locus_tag="IV356_001410"
     CDS             complement(26342..27265)
                     /locus_tag="IV356_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAP9015104.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(27486..29978)
                     /locus_tag="IV356_001411"
     CDS             complement(27486..29978)
                     /locus_tag="IV356_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HAP9015105.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(29985..30452)
                     /locus_tag="IV356_001412"
     CDS             complement(29985..30452)
                     /locus_tag="IV356_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HAP9015106.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(30588..30661)
                     /locus_tag="IV356_001413"
     tRNA            complement(30588..30661)
                     /locus_tag="IV356_001413"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(30625..30627),aa:Arg,seq:acg)
     gene            complement(30719..30792)
                     /locus_tag="IV356_001414"
     tRNA            complement(30719..30792)
                     /locus_tag="IV356_001414"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(30756..30758),aa:Pro,seq:tgg)
BASE COUNT         8934 a         6565 c         5760 g         9552 t
ORIGIN      
        1 aaatatctat tttgtttgat tgttcattgc gtcttctgca gccatttgcg cttcaatatc
       61 tgaaatactg tagacatttt cgcttgctac accgacttct tttggttcca tgtcacgata
      121 acgttgcata ccagtaccag ctgggatgat cttacctata ataacatttt ctttcaaacc
      181 aagaagagga tctttcttac cgcggatcgc agcatccgtc aagacacgag ttgtttcttg
      241 gaatgatgca gcagataaga aactatttgt ttctaatgat gcttttgtga tacctagtaa
      301 gacaggtcga gaagttgcag gaacgcctcc tgagactagc gtattgtagt tttgatcttt
      361 aaagtctgcg atgtctaata atgtacctgg taagatatct gtatcacctg gatccattac
      421 acgaacttta cgcagcattt gacgaaccat tacttcgata tgcttgtcgc cgatttctac
      481 cccttgcata cggtaaacac gttgtacttc acgaagcaag tagttttcaa cagataatac
      541 atcgcgaact tgcaacaatt gttttggatc gattgatcct tctgtcaatg gtgcaccacg
      601 gtggatcata tcgccttctg ctactttcat acgtgctgta taaggaacag tatacgtacg
      661 tgtatctgtt tttcctttga ttgttacttc tttggtacgt gttgcaggat cttctgagat
      721 atcgatgaca tcccctgtta cttctgtgat cactgcttgc cctttcggat tacgtgcttc
      781 aaagatttct tggacacgag gaagaccttg agtgatatcg tctccggcaa ccccacctgt
      841 atggaatgta cgcatcgtca actgagtacc aggttcaccg attgattgag cggcgatcgt
      901 accaactgct tctccgactt caacgtcaga gccagttgca aggttgcgtc cgtaacaatg
      961 tttgcagaca ccatgttttg tattacatgt gaagacagaa cggattgtca ctgtttcgac
     1021 acctgcatca acgatttgtt ttgcgatgtc ttcggaaatc aattggtttc ctgcaatgat
     1081 caattcattt gtttcaggat gacgtacttc tttacgggtg taacgtccca ctaaacgatc
     1141 ttctaatgat tcgatgattt catttccctc gcggatggct tggatttcaa gacctcggtc
     1201 agtaccgcaa tcttcttcac ggatgattac atcttgggcc acgtcaacca gacgacgagt
     1261 caagtaacct gaatcggcag tcttcaaggc tgtatcggtc atccctttac gagccccgtg
     1321 agttgagata aacatttcca agacggatag tccttcacgg aagttcgaaa tgattggcaa
     1381 ttccatgatt cgaccattag gagcggccat caaaccacgc attccggcaa gctgtgtaaa
     1441 gttggaaatg ttaccacgag ctccagaatc agacatcatg aagattggat ttttcgcttc
     1501 caaaccttcc atcagttttt gttggatgct gtcttttgca gcattccaaa cagcaatgac
     1561 acgttcataa cgttcgtcat ctgtgatcag accacgacgg aattgttttg taatagtttc
     1621 aacttgttta tgggcatttt caatgatttc ttgtttttca ttcagtacac tgatgtcagc
     1681 gatccctact gtgataccgg catgtgtcga atgtttgtac cctaagtctt tcatacggtc
     1741 aagcatctta gaagtttctg ttactttgaa tcgtttgaag acttctgcga tgatgtttcc
     1801 taagtttttc ttcttgaacg gtaatactaa ttcttgctct ttgatatgtg caggaatatc
     1861 agtaccagct tcaacaaagt atttgtccgg tgtttggacg gtcaagttga agtctgttgg
     1921 ttcattcaga taagggaatt caggaggcat gatctcgttg aagatgatct taccaactgt
     1981 tgtgatcatc gtacgttctt tttgccattc agtaaatggt ttttcaccta atgagttagg
     2041 gttcacaccg atacgtgaat gtaaatgaac atatccgttg cgccatgcga taacggcttc
     2101 gttttgatct ctgaagacca ttccttcgcc ttcgcgtcct tcttcttcca ttgtcaagta
     2161 gtagttacct agaaccatat cttgagaagg agtaacaact ggtttaccat ctttagggtt
     2221 caagatgttt tgagcagcta acatcaacat acgtgcttct gcttgtgctt cttcattcaa
     2281 tggaacgtgg acagccattt ggtctccatc gaaatcggca ttataagctt cacatacaag
     2341 tggatgcaaa cggattgcgc gtccttgtac taaaactggt tcgaatgctt ggataccaag
     2401 tcggtgaagc gtaggtgccc ggttcagcaa tactgggtgt tccttgatta cgtcttctaa
     2461 aacatcccat acttcgtctt cttgacgttc gattttacgt ttcgcatttt tgatgtttga
     2521 agctagttcg cgttgaacaa gctcacgcat cacgaatggt ttgaataatt caatggccat
     2581 ttcttttgga agtccacatt ggtacatctt caagaaaggt ccaacaacga taacggaacg
     2641 acctgagtag tcgacacgtt tacctagcaa gttttgacgg aaacgacctt gtttcccttt
     2701 caacatatga gaaagagatt tcaatgggcg gttacctggt ccagtaactg gacgtccgcg
     2761 acgaccgtta tcgatcaatg catctactgc ttcttgcagc atacgttttt cattttgaac
     2821 gatgattcca ggtgcattca agtctaacaa acgtttcaaa cggttattac ggttgattac
     2881 acgacggtaa agatcattca agtcacttgt tgcaaaacgt ccaccttcta attgaaccat
     2941 tgggcgtaaa tctggtggaa taacagggat aacgtccata accatccagc ttggttgatt
     3001 tcctgaagcg cggaatgctt ctaaaatatc caaacggcgg attgcacgtg tacgtttttg
     3061 tccttgtgca gatttcaatt cttctttcaa ttcggctgct tctgcatcta gatcaacatt
     3121 atcaagtaat tgtttaatcg cttctgcacc catagcagct tggaattctt gtccatattg
     3181 ttcacgtttt tcgcgatatt cgcgttctgt caacaattgt tttttctcta aattcgtatt
     3241 tcctggttcg atgactacat atgaagcaaa ataaatgatt tcttccaaag cgcgtgggct
     3301 catgtctaat acaagaccca tacgtgaagg aatcccttta aagtaccaga tatgtgaaac
     3361 aggagctgct aattcaatat gtcccatgcg ttcacggcga actttcgaac gagtaacttc
     3421 cactccgcat cgatcacaaa cgattccttt ataacggata cgtttgtatt ttccgcaggc
     3481 acattcccag tcttttgtag gaccaaaaat ccgctcacag aacaaccctt cgcgttcagg
     3541 ttttaaggta cgatagttaa tcgtctcagg tttttttact tcaccgtaag accagcttct
     3601 gattttttcg ggagaagcca aacctatttg catactttcg aatttattta catcgatcaa
     3661 aaggggttcc ctccatttca tttaatggca aaccgcaaga cggctgatct tcgaccgcct
     3721 tgcagctcat agaccggatt agtctaaatt atcttctgcg gtttcaaagt tttggatgac
     3781 atcgtctttt tcatcttcca cttgttcagc agctttcttt tctaattctt tggcagtttg
     3841 ctgttcggca aattttgtca aagcatcaac agtgatcaaa tcgtcgtctt catcgtccat
     3901 gtcgcgaagt tcgatctctg tttcttcgat atccaagaca cgcatgtcca gacctagtga
     3961 ttgcaattct ttcaccaata cgcggaatga ttccggtaca cctggttttg gaattggttc
     4021 acccttgacg attgcttcgt atgttttcac acgtccgact acgtcatctg atttgtatgt
     4081 caagatttct tgtaaagtat aagccgcacc gtaagcttcc agtgcccata cttccatttc
     4141 accaaaacgt tgtccaccaa attgagcttt acctcccaat ggttgttgtg taaccaatga
     4201 gtaaggtccg attgaacgtg catgcaattt gtcatcgacc atgtgagcaa gtttgatcat
     4261 gtacatcaca ccgacagaca cacgtccatc aaatggttca cctgtacgtc cgtcgtacag
     4321 aacagttttc gcatcgctgg ccataccggc ttcacgaact gtttcccata cgtcttcatc
     4381 acttgcacca tcaaatactg gcgttgctac gtggatacct aactgacgtg cagccatacc
     4441 caagtgtaat tccaatactt gcccgatgtt catacgtgaa ggcaccccta aaggattcag
     4501 catgatatcg attggtgttc catcaggtag gaatggcata tcttcttccg gcataatacg
     4561 ggatacaacc cctttatttc cgtgacgacc ggccatttta tccccttcat ggattttacg
     4621 tttttgaacg atataaacac gaactaacat gtttacgcct ggtgacaatt catctccagc
     4681 ttcacgagta aagattttca catcgtgaac gataccgccg ccgccatgtg gtacacgtaa
     4741 tgatgtatcg cggacttcac gagctttttc gccaaagatc gcatgcaata gacgttcttc
     4801 tgcagataat tctgttaccc cttttggcgt gactttccct acaagcaaat cgccatcttg
     4861 gacttctgca ccaatacgga tgatacccat ttcgtctaaa tcttttaatg cgtcttcccc
     4921 gacattaggg atttcgcgtg tgatttcttc aggtcctaat tttgtatcgc gggcttctga
     4981 ttcatattct tcaatatgga tagaagtgta tacgtcatct tttaccaaac gacggctcat
     5041 gatgatcgca tcttcatagt tgtacccttc ccaagtcatg aaaccaacta aaacgttttg
     5101 gcctagagcc atttcgcctt gttccataga tggtccgtct gccagagtat cccctttttc
     5161 gactttctca cccaaatgaa cgattggacg ttggttgtag cttgttccgg agtttgaacg
     5221 acggaatttt gttacatcgt atttatctaa tgcaccgttg tcgcggcgta cgcggatttc
     5281 agaagcatca acgtattcaa cgacaccgtc atgtttacat aacaaagcag ctcctgagtc
     5341 atgcgctgat ttgtattcca taccagtacc aacccatggt gcttgaggat tgatcaacgg
     5401 cactgcttga cgctgcatgt tggcacccat caaggcacgg ttggagtcat cgttttccaa
     5461 gaaaggaata catgctgtcg caacggcaac tacttgttta ggtgatacgt ccatgtagtc
     5521 tactttatca atagatactt ctaagttttc actttgagca cgagccataa caacgtcttg
     5581 agcaaatgtt ccatcttcat tcaatgggct gtttgcttgg gctacgatgt aatggtcttc
     5641 gatatcagct gtcaagtagt cgatttggtc agtaacacga cctgtttcac ggtctacacg
     5701 acgataaggt gtttcgataa atccgaattt atttactttc gcataactgg acaaactatt
     5761 gatcaacccg atgtttgggc cttcaggagt ttcgatcgga cacatacggc catagtggga
     5821 gtagtgaacg tcacgaactt cataaccggc gcggtcacga gtcaatccgc caggtcctaa
     5881 ggctgaaaga cgacgtttgt gtgtcaattc gccaagaggg tttgtttgat ccatgaactg
     5941 tgacaactga gaagaaccaa agaattcttt gatacttgcc acaactggac ggatattgat
     6001 caattgttga ggtgtcaatg tttcagtatc ttggatcgac attctttcac gaaccacacg
     6061 ttccatacgt gctagcccga tacggaattg gttttgtaaa agttcaccga ctgaacggat
     6121 acgacgattt cctaagtggt cgatatcatc gacattgccg ataccttcca tcaagttcaa
     6181 gaaatagctc attgaagcaa tgatgtcggc tggacgaacc gtttttacag ctgcttctgg
     6241 atagccgttt ccgatcacgt ttacttcacg ttcagggtct cttggtgaaa atactttgat
     6301 gacttggaca gtcattggat ctgtgaccac accgtcttct gatggatagt aagtcactga
     6361 atttaggcca ttatcaatga aaggagctag tgtttccatg acttggtgag tcagaactgt
     6421 tcctttttca acgatgatct cgcctgtttc tggatcaact aatgtttcag ctaatgtcag
     6481 attcaataga cgtgttttca aatctaattt tttgtttact ttgtaacgac caacgtttgc
     6541 taagtcgtaa cgttttggat cgaagaaacg agcattcagc aagttacgtg agctgtctgc
     6601 tgtttttggt tcgcctggac gcaaacgttc gtaaacgtct ttcaaacctt cttctgttct
     6661 tgagtcgctt gcgtttttat gcaagtcttt ttcgactgta ttgcgtaatg tttcgctgtc
     6721 gccgaagatt tcaaagatcg tatcatcgga accaaatcct aacgcacgaa ctaatacggt
     6781 taaaggaatc ttacgtgtac ggtcgatacg tacataagag atgtcttttg catcagtttc
     6841 catttctagc caagctccac ggttagggat aacagtagaa ccgaatcctt cttttccgtt
     6901 tttgtcgact tttccatgga aatagacacc tggtgaacgg actaactgag aaacgattac
     6961 tcgctctgcc ccgttgatga tgaatgttcc ttgttctgtc attaatggga aatcaccgaa
     7021 gaatacttct tgtgctttga tttcgccagt ctcgcggttt gtcaaacgca atgttacatg
     7081 taatggtgca gagtagtttg catcatgcgc acgagcttct gctactgtat actttggttc
     7141 tttcaattca taatctacaa attccaaaga tagattgcca ttgaagtcat cgattggcaa
     7201 aatgtcttca aacatttctc taagtccctc atctaagaac cattggtaag agtctgtttg
     7261 aatttcgatc aaatttggta attccaacac ttcactgatt cttgcgaaac ttctacgttc
     7321 gcgatgtttt ccgtatttta ctacgtgtcc agccaagctc ttcacccctc taaaatgtca
     7381 ttcaaaaaga ctacccgatc aattgttaca ataatatttc gaatattatt tttaggtaac
     7441 aacagacatt ttttgcggct tttaggcaaa aaaaaaccaa aaatagaaca ttctcttgaa
     7501 accttacttc gtgagcttct acttttgttt ccttatatta aagccgaaac ggacaatatt
     7561 tcgtttctgc cttttcttca tcagatagtt tttgcaactt catatactac acttattttc
     7621 tataaaagtc aacacttcct ggcgtttctt ctgctttttc gcaacatttt cttaatgttt
     7681 tcaattttat gttttcaatt atctgacaat tcttaattga cagacctttt tatctcggtt
     7741 atactttaga aaattcattt tgtggaggaa cttctatgcg aaccaacatc aaccaaatcg
     7801 caccaacaca actgaataac ttttacttta gctactttag ataggtttgt attcatcatg
     7861 atggatacaa acgttaaacg acagtttgta tctatgatgg ctaaagaact ttgtattgca
     7921 gcaaaaagcc acgtagacaa aatgctaagt ggctgagcag tgaaaataca aagtaaaagt
     7981 atcaagcatt ctactttttc aatttatttt ccgacttttc aatccatttg gacattttgt
     8041 ctgaatggat tttttgtttc ccaaaattaa ggaggaaaaa gaaatgaaaa aaaatataat
     8101 catcggatta ggcgctgccc tgctactagc tttaggaggt tgcgcacaaa aagacaattc
     8161 cgcagaggca tcagatggac aaaaaacaat tggcgtattg caacttgtac aacataactc
     8221 gttagatgct gcctataaag gattcaaaga aggattagca gaagaagggt ataaagaagg
     8281 cgataatcta acaatcgatt atcaaaatgc ccaaaacaat caagacaacc tgaaaagtat
     8341 gagtgagaaa ctcgtcaaag aagatcctga tttgctactt ggaatcgcca ctccagcagc
     8401 acaatcttta ttaaatgaaa caaccactat cccgatgact gtcacagcgg tcacagactt
     8461 ggaacaagcc catttagtca catccaatga aaaacctggc ggcaatgtga ctggcacgac
     8521 agatatggtg ccaatcgaaa aacaaatcgg cttactgtta aatatcgtgc cagacgccaa
     8581 aacaatcggc atcatgtata acaacggtga agcaaactct aagatccaag ctgatttggc
     8641 agaaaaagaa ttgaaaaaag cgggcgtcaa agtcaaagta ctgacagcaa attccacaaa
     8701 tgatgtccaa caagtgacga aaagtctagc taaagatgta gatggaatct atattcctac
     8761 tgataacacg ttcgcaagtg cggcaagtgt tgtcggtgaa gtcgcaaaag aaacaaaaac
     8821 acctgtcgtt gctggcgcag ttgatcaagt caaagacggc ggtctagcaa cagtaggaat
     8881 cgactacgaa agcttgggca aacaaacagg gatcatggca gcaaaaatct tagacggcaa
     8941 gaatccaagt gaacttcctg tcgaaacagc gaatgatttg gaactgtatg tcaataaaga
     9001 catggccaaa gcattaggca tcaatccaga cagcatcaaa gaagctgaat aaaacacagg
     9061 aggattctca tgacaaattt gctctctctt ttcttatcat ctgcatcgca aggggtctta
     9121 tgggccctac ttgcgattgg tgtatacgtc actttccgta tcttggacat tgccgacttg
     9181 actgctgaag gaagctttcc tttaggtgca gggatcgcgg cagtaagtat tacaaatggc
     9241 tatcatccat tgacagcttg tcttctaggc tttttagggg gtgcggcagc agggcttgtt
     9301 tccggactgc ttcacacaaa attgaaaatt cccgcccttc ttgcagggat catcaccatg
     9361 actggtttat attctgtcac atcccgtgtg atgggtgcgc cgaacatctc tttattgggt
     9421 cagccaacga tctttcattg ggtcgagtca ttcggcataa caaaagacaa cgctgtactg
     9481 atcgtcggtc tgctttttgc tttgatcgtt gtatgtttac ttgttttgtt cttacgtaca
     9541 gaaacaggac ttgctattcg tgcaactggc gataatctgg caatgagcga agcaaacggg
     9601 atcaacacag ataatatgaa gatcatcggt tatatgattt ctaatggatg cattgctctt
     9661 tctggctcct tacttgcgca aaacaacggc tttgctgatt taaattctgg tattggaacg
     9721 atcgtaattg gacttgcttc tattatcatc gcagaagttt tgttacgtaa ccagccacta
     9781 tttctccgtc tcttgactgt cgttttaggt gcggtcattt atcgttttat tttagcgtta
     9841 gtcttcgaac tgaatgttga accaagtgat tcgaaacttg cttctgcttt cgtgctagtg
     9901 atctgtcttt ctttcccgca gatccagcaa aaattccatt tacctcaaaa aaagaaaggc
     9961 ggtagtgtca aatgaatgac gtcttaacat tggaaaatct ccatcatacc tttgaaaaag
    10021 gaacgatcaa cgaaaatcat gtcctgaaag gcattaatct ttccttagat cccggcgact
    10081 tcgtgacgat catcggtgga aatggggctg gtaaatctac tttgctgaac agcatcgccg
    10141 gtacattttc tgtcgatcag ggtcaaattt tattgaatgg aaaaaatatc acgaaaaaat
    10201 ctgttgtcga acgttcgaaa tccatcagtc gcgtattcca agatcctaaa ctagggacag
    10261 ccgttcgttt aacggtagaa gaaaatcttg ctcttgctat gaaacgagga aaaaaacgcg
    10321 gcttcttccg tggtgtcaaa ccacaagacc gaacattttt caaagaccag ctggttcggc
    10381 taaatttggg gttggaaaat cgtttatcct cagaaatcgg tttgctgtct ggaggacaac
    10441 gtcaagctat tacgttattg atggccacat tacagcgtcc agaactgatc ttattagatg
    10501 aacacactgc agcgcttgac cctgctactt ccaaaacggt gatggaattg acagaaaagc
    10561 tgatcactga gcagaatctc actgctttta tggtcactca tgacatggaa gacgcgatcc
    10621 gctatgggag tcgactgatc atgctgcatc aaggaaggat cgtcgtagat atccagcaag
    10681 aggaaaaaca gcagctcaca gtgccccaat tattagcgtt gttcaaacaa aacagcggca
    10741 cggcattaaa agacgatcaa gtacttttat cttcataatc agaaagagga tgggacaaaa
    10801 aatgaacgcc caccctcttc ttttttctct ttccttcttt cgtttttgct ttatgtatca
    10861 accgttgttt cttcgaaaac tattttgttc tctccttctt cctgatagaa tggatgggaa
    10921 aggagcttga tgccatgaca acgaaagaca aggtacttca attattgaaa aagacaccag
    10981 attttctttc cggagaaaag ttggcacagc aactggaagt ttcccggaca agtatttgga
    11041 aagccatcaa agaattggaa aaggcaggct atcgttttga gcacgggcct acagggtatc
    11101 gttacctgcc ctctgacgta ctagatgcaa aagaaatcca gcaagagcta cggtcgttta
    11161 ttcctgattt gaaagtacaa acgatgttga cttctgaatc tacgatgaaa gatgccaaac
    11221 tggcagcagc tcaaggagat tctgtttcga agttatttgt tgctgataca caagaacaag
    11281 ctcgtggacg ttttggacgg ccttttttcg ctgaacctgg acgaggaatc tacatgagtc
    11341 tcttgctcca tccagacaaa cggtttgatg aattgcctca atatacgatc atcgcagcca
    11401 gtgcctgtgt gaaagccatt gaatctgtaa ccggtcgttc tgcttcgatc aaatgggtca
    11461 atgatatcta catggatgga aaaaaagtct gtgggatttt atctgaagca gtcagtgata
    11521 tggaaagcgg caggatcagt catatcatca ttgggatcgg gcttaatttt tctgttcctc
    11581 aaaatcattt tccagctgat ctccaagaaa aagccatctc tgtctttccc gacggacaag
    11641 ctagtgtcac aaggaatcag ctaatcagca aaatctggca agaattgttc acttatcttt
    11701 ctcacccaga aaaagcgttg gacttctata aagaaaaatc attcgtattg ggaaaaaccg
    11761 tgtcgttcaa tcaaaaagga acgacttatg tcggtcttgc aaaagaaatc ggtgatcatg
    11821 gcgaactgat cgtccaaaca aatgaacaga agatgagttt gtcttctggc gaaatcagtc
    11881 tcacatctat ccgtacgcaa taattatcag atttcacaaa aggacacctg atctcataca
    11941 gtgtcctttt ttctgaattc tcttcaaaag actctcctta ttctatcagc tgacagtttc
    12001 tctatcctct agaaaaaggt attctaaaaa tatctataaa gcatggtaca ctttctttaa
    12061 atgaatcaat gcaaaaaaca agagagtcat cagtttacac gatcaaaaga gatagcaggc
    12121 cgcttccttt ttcaatctta tagatagacc atgggtaacg ataaaaacaa aaaagaactt
    12181 gcgacttatt ttgccgtaag ttctttttta gctagtgcct taatctctta atcccaacaa
    12241 acgtctcgca tagatcacct gaccagagtg catagcagca tcatcaataa tagaaacgag
    12301 acgcattcct cgtgtgactg gtggtgtcca gttctcgtca attacttcat ctagctcgga
    12361 aggttccagc cttcttaagt aagaaatagc aaaatcagca gctcctcgca agtatcctag
    12421 cagatcttct atttgattag cttggatctg ctttgcttgt tccagactat gcttccaatc
    12481 ttgttcgtta tctgctatcg tcatcggaaa ccggctttcc cagtcttgac tatgccaaat
    12541 tggagaagtt cctgctaaat cagcaatctg gaaatctaat tctcgagcgg tatgccaagc
    12601 cagccaagtc attgatttga tctgcggggc tctatcttcc actggaaaac gattggcctc
    12661 ctcaatagag acgccttcaa acaaacgttc aaaccgatcg tatgcccgat ccacactctc
    12721 gcatagcata tctaaataat ccatttattt tcctcctttt tatttatcct acttactttt
    12781 tcctaattct aggataccta cttatatgtt actacacacc cttatttttt acactttaac
    12841 agtcaccatc atcaatagtt tggagattga aagaaaaaga tagtgtcgaa ctatcaattg
    12901 aacaagaagc aacaatatga acgtttcatt aatattcttt aaataaacaa tgatttttca
    12961 aacgaacagt ttaagactag gagaaaaaga gtataatagg aaaatgtttg aaaggaaagg
    13021 aaggggaaaa atgaaaaaaa gggcaagttt actagtccta gttgctttgt tgttcaatat
    13081 cttttcgtat ggtgtggccg tttcagcgga aacatacatt cctaaagacc ctgggaatat
    13141 ttataatgat ctaactggta actatggctt gttaggaatt gctagtcaat tccacgtatt
    13201 tgctaaaaat aagacaactg tgaatgcaca tacagacgga aatatagcaa cacatgaact
    13261 tgatgcaaaa aataattttg gtacagagct tcatgaaggt ttattgaacc aagaaataaa
    13321 ttatatacaa aaaactgatt ctttcgctaa ttcttcaggc atacctacag gtagcacaag
    13381 aatgaataaa tttgtcgttg gcagtaacgt ggatgtagca cttcaagatg gtcatcctac
    13441 agtcaatgga tccaggcttg atcacttaac tccagatgat ttttataaag atcgtgctgg
    13501 gcatgaatat attgatttcg agcaggaatt tgctaaattg aatgtagcag caaatgatct
    13561 tgcaacgatc actccagcta aaacatatac tgctgcagat tttccagaca tgaacaatcg
    13621 gacaatcgat ttaactgatt tatcagatac cgggttttta ttggtaaata tcgatgcaga
    13681 agtgttaacg atgaatacgc cacttcaaat cattaatcca aatgatcaag tagttgtatt
    13741 taatgtcatc aacagttctt ctgcattgaa cgtacagtca ccaatcaaat acaatgatcg
    13801 ttcaaatcat gaaacagaag atttttcgga tgcgaatatc tcttggaatt ttggaaatga
    13861 gatgactgat ttgacaatca gtgctccttt tcaaggaaca atccttgcgc ctaatgctac
    13921 tatccgcatt actcaaaacc aagacggaac gattatagga acaaatgtga ttttagatgc
    13981 agctaccaat cgttgggatc ctaacgaaat atttatcagc gacaatggta cagatacgac
    14041 agacacaagc gacagtacag atacatctac cacaagtgat agctcagatt catcaacttc
    14101 aagcgacagt acagatacta cctctaccac aagtgatagc acggatacat cagcttcaag
    14161 cgacagtaca gatactacct ctaccacaag tgatagcacg gacacatcag cttcaagtga
    14221 cagtacagat actacctcta ccacaagtga cagcacggac acgtcagctt caagcgacag
    14281 tacagatact acctctacca caagtgatag cacggacaca tcagcttcaa gtgacagtac
    14341 agatactacc tctaccacaa gtgatagcac ggacacgtca gcttcaagcg acagtacgga
    14401 tacatctacc acaacaagtg atagcacgga cacgtcagct tcaagtgaca gtacagatac
    14461 tacctctacc acaagtgata gctcagattc atctaccact acaagtgata gcacggacac
    14521 gtcagcttca agtgacagta cagatacatc ctctaccaca agtgatagct cagattcatc
    14581 aacttcaagc gatagtacag acacgtcgtc taccacaagc gatacacgtc atgcaagtgt
    14641 ctccttctca aaaacaagtt cggataacag gacgaacttt aacttaacta ataaaacaag
    14701 caatgacaat ggaaacaaat caaaaagagc acttcctaaa actggaagtc aatcgaataa
    14761 ttggataaca ctcgcaggcg ttatattact tgtaatcggt ttaagaatca cttttatgag
    14821 ttataagaaa tcgaaaaggt aaaaaaatat tcaagataaa aaagagcaac gtcgctaacg
    14881 gacgttgctc tttatttttg ctttttatca taaatacaag aactacaatt caatttgtca
    14941 aaaaacacgt agatttcctt ctgagaaatt tatttacgta tcgaaccttt ccctattcag
    15001 tctttgcgat ccaaaatcag ttgggtaagg gaaaagagat tctcttttgt tcgaagagag
    15061 gtggcaggta atttctttat ttccttcaaa gccttttctg tgtaagaggc cgctaacttc
    15121 ctagcttctt ccacgcctcc tgtatgttca acgattttgc gtacggcgtc gacatcttct
    15181 tctgtcattg ccgctttctt ctctaaataa ggtagtagct ttggtttgtt tttttgcaaa
    15241 gagtagatca acggtaaaga atagacccct tgacgcatgt cttctagtac aggtttgccg
    15301 atttcctggc tctcttttgt ataatctaaa atatcatcga taatctgaaa ggccatcccg
    15361 atagaaagtc cgatatctcc tgcttttttt gcgaagcgct cgcttgttcc actttcaaaa
    15421 gcgccaacag aacaacttaa ttggaacagt tcagctgtct tacctgaaat attttccaaa
    15481 tattctttta cagaaagttc ataattatag cgatcatcca tctgccctaa ttcgccattc
    15541 aatacttttt ccatactgcg agaattcaat tggagacttt tcaaggaagt ggagtaatca
    15601 gacaatagtt taaaacagca gacaaataaa tagtctcctg catagacaga aacgacatta
    15661 ccaaactgac tacggatatt aggctgacca cgtcgcagat ccgcttcatc aacgatatca
    15721 tcatggatca gtgtggccgt atggagcatt tcgatagaag ctgccaaagc gatggctttg
    15781 tctcgatctt gctctggtcc aaattgtgag aacaatagct gataggcagg acgcaacagc
    15841 tttccgccgg catggatcgt ttctttgatg gcttgttcga caggtttgtt tttcaggcgg
    15901 acagtttctt ccatccgttt tagtgtttct gtcaattctt tacttaaagc aggatagttt
    15961 tcccacattg gatgtagctt cataaaaaaa ctccttgtgt gacgattatt ttttggtaaa
    16021 cattgggctc catttttgtt tggttccctg ctcataatct ttttggaatc gttgaagtgt
    16081 ctgcacatgt cgtaaaagat aattcgctgc gatcccgatt gcaatccctg ataaaatccc
    16141 taaaactgaa aggactggca agtacaacat gactgtccat gattgtgcaa tgaaagaagc
    16201 catcaaaagc tgtccgacat tatgcatgaa accgccggcc gcactaattc cgatgatact
    16261 gacacgtttt ggtcctaatt gcttgaccaa taacattcca aaataactaa gcaaagcacc
    16321 actcatacta taaaggaatg tggaaatcgt tccgcctagc aaagtagtca ggaatagtcg
    16381 tagccaaagt agtaagaagc tgtcttgttt tttcatggta aaaatggcaa cgatcgtgat
    16441 tagattggct aagcctagtt ttgcaccagg cgcaaaagaa aaaggataag ggatcatatt
    16501 ttccaataaa ccaatgatca ctccttgtgc aacaagtagc gaaatataaa tcattttttg
    16561 taatttactc atggtgtgtg aaggtctaat aaatcagact gtcttcgtca cctccatctg
    16621 ttgaacggac ttcgatcact aatttatgtg gcaaacagac gatggtttcg ccatttttcg
    16681 ttgcccagcc tcgacgtacg cagatctggt catcgcaatc tgcttctttt atccgtactc
    16741 gatcgccatc tatctcgatc aagttataat ctccgtgttc atctttgtaa gtatatgtgt
    16801 tgctctcttc tccagccatc aaagggaatg ttttgatttc tgtgccatcc acacgcagta
    16861 ccgcttcttt ttctgctgtt gcggtgtttt gctgaagacc aaaaatcatg actggtaaaa
    16921 aagaaagaac agtcaaaagc aaaataataa aaacatccca aggtttgagc agactttttt
    16981 cagcaaattc tttaaggctc atttttgttc tcctttttcc agattaactc acccaatttt
    17041 agcataaaaa caagaggttg tgacacctgt gtcttgcttt gagtaataag aacgaagaat
    17101 agaaaacagc tttccatgtt ttctaattct ttgggcttat taccgagaag cagcaggtgg
    17161 aacaccgttt ataacaagag gttgtgacag aagtgggcaa cttcaagaaa taagaaggaa
    17221 tttacgaaaa ttacttttca agtttttgtg aaatttcggc ttatttttcg aagaagctac
    17281 ttctggaaca ccgtttataa caagaggttg taacagaggt tgtgacacct gtgtcttgct
    17341 catggaggct tatctcgggc atcttattcc tttaatttta cataaaaagg aggctgtgac
    17401 ggtttgtctc agcccctttc tattgaaatc ttgcattcaa ataacgttct ttatctattt
    17461 atttcttgcc gtactgggaa cttggtctac cgtaccacca attacctagt gtacgttgta
    17521 gccatggaat tacccagcga tccaacccaa tcgcacgtcc ggaaccgttc atcaatgcga
    17581 aagcaacaaa aatgaaccaa atgtttaccc agtaaaacat gcctgataag cagaacgtga
    17641 tcaccaatac aatcgttgtc gcactgcata gccatgtgaa taatccagca atcaatgcta
    17701 atgccaaggc aatttcaaag aataccatga atttttggaa gaacattgct acatcattgt
    17761 ttggcatgat cacttgcatg atctttgtga accagtctgg tgacttctca atcacagcca
    17821 ttggttcttc accgtatgca taactcaaac caaaatgtgc agcttgagtc gctgcttctc
    17881 cggcacttgc ccctgctccg ctggcagctg tggttgcatc accagcagca gaagcaccac
    17941 tggcaacatc tgttacattg tattcccatg tccaagggaa cacactgttt ccagtgaacc
    18001 atgatccttc accaaaccaa gtacttggtt tgaacacttc accattccca atgatttttt
    18061 tggaagcttc aacgaaccaa actaaaccat agaaaatacg aagtggcaca ctccataaga
    18121 cattgccgta acgagaagaa tgtcctcgag tcacgttgcg atcatctttg atatggaaaa
    18181 actcatgcat taaatattgg aacatataat aaccagaacg aatatcaaag aagtatttca
    18241 aattcacgat atgtttcatt acgatagcta aaaatccgct taaatggatc ttatcaaata
    18301 ggttagctac cccccatttg gcaccaatag aaaccataaa tccttgatag tttcctttaa
    18361 atttatgctt ttctccgcct ttgatcgaag ccacgatatt cgctgcggct gtgtgtcctg
    18421 tttgttcagc agcttgaacg atctgcggtg tcggtgttcc tgggaattct tcataaaaga
    18481 ctaaatcacc aatgatatag atgtttttat cttcgtagcc ttttgcctgc atatattcat
    18541 tggcgatcaa ccgctgtccg cgtgctgatt ctaatccaaa gtcagcagcg tcagaagttc
    18601 ctttgacacc agctgtccaa atcagtgtgt gagtcggaat gttgcgtccg tctttcaatt
    18661 tgatatgatc agcagccact tctacgattg gtgcattcaa taataattcc acgttgtgct
    18721 tacgcaaata gcgttcagct tttgcagcat catttcgatc caacatattc aagatcgtcg
    18781 gcattgcctc tacgaccatc agtgtgattt cgtttggatc taatttataa tctttggcta
    18841 ggcgattttt ccagtcgatc agttccccaa tcatttcaat accggtaaat ccagaaccac
    18901 agacaacgaa agtcagcatg gctttacgca gttcatcatc tggttccaat gcagcttttg
    18961 ctactgtctt ctcaatatgt tcccgaatcc ttacagaatc ttcaaatgac caaagggtga
    19021 atccgtgtgc tttgacacca ggtgtaccaa agtcattcgg ctctccgccc attccaagga
    19081 tcagctgatc aaaaggatag gaacctaatt tggtcttgac gatttttcgt tctttatcga
    19141 taccgattac agtgtctgtg acaagttgta cattcttttg acgagcaaac aaatgctgca
    19201 gatcgtattg gattgcttct ggttctacac gtccgccagc tacttcatgc aactcggtca
    19261 tcatagtatg gtacgaatga cgatcgatca gagtaattgc tacatcttct tttttcagtt
    19321 tctttgccaa gtattttgta gctgaaacac cggcatatcc tgctcctaca acgacaatat
    19381 tttgctttgc cattgatcat ccgctcctta tagactatct atataatgaa tatatgataa
    19441 ttcttttagt ttgatactta ttacacaatc tccatatatt atatagatgt tctgttcttt
    19501 tgtctaactc cttttggatt tttttcaaat tttaaaataa agcgtttttt cacgaaattt
    19561 gctgaaagaa aacgtttgaa atattacatg ggttatttat caaaaatagt tgacttatag
    19621 gctaaaaaga ttagaatgta taatgaatca caaagaaaaa ttgtggacta gaaatggaat
    19681 ggtggggtat taaaatgaag aaaaaacgtt ttgtaactgg atttgccgta ttagcatttt
    19741 cagctctagt gttaggcgct tgcggcgcag atgacaacgg aagctcaaac tcttcttctg
    19801 aatcatctac agcacaatct tcgactgcaa aaagcacaac agaatcatct gcaaaagttg
    19861 tagctggcgg agatttgcaa gacggcacat ataaattaga agaaaaaaat tattcaaatg
    19921 gttaccgtgc agtctttgaa atggttgtaa aagacggcaa aatcactgaa tcaaaatatg
    19981 ataacgtcaa tgaaaacggc gaatcaaaaa caaaagatgc agaatacaac aaaaacatgg
    20041 aagcaaaatc tggcacaaac ccagaaaaat acattcctga gttgaatgac caattcttaa
    20101 aagcacaaag cgcaagcggt gtggaagtcg taactggagc tactcactca tctgaaagct
    20161 tccaaaacta cgcacaacaa ttgatccaag ctgctcaagc tggtaacaca gatacaatcg
    20221 aaatcgacaa tggtgctgat ttgaaagacg gcacttacaa gcttgaagaa aagaactact
    20281 ctaacggcta ccgtgtgcaa ttcgaaatga cagttgctgg cggcaaagta actgaatcaa
    20341 actttgatta tatcgacaaa gacggtaaat caaaacaaga tgatacagaa tataatgaaa
    20401 atatgaaagc aaaaagcggt acagaaccaa aaacttacat ccctactctg aacgacgaat
    20461 tcgtcaaagc aatgggcgaa gaagatggct cacctgctaa tgtagaagtt gttacaggtg
    20521 ctacacacag ctcacattca ttcatcatgt acgcacaaca attagtgaat gcagctgaaa
    20581 aaggcgacac tcaaacaatc gaagtagata atatcgtaac agaaaaataa tcacataatc
    20641 atactaataa aagttggagg gtgggacgat agccagatta ggcagtcgtc tcacctttca
    20701 aaatgaagag aggaaaaaga tgcggaaaaa actactattt tccttaatca cactgggcat
    20761 ctcttttatg gtgctaactg gctgcagcaa ctcagcaaat aaaacaacca ctgaaagttc
    20821 agcagctacc aagatattga aagatccata ttctgatgaa cagttcttgt tagggactta
    20881 cgttcgtatc cgtgtgtatg atgaaggcaa agaatcagca ttgaaacctg ccttcgatcg
    20941 agtaaaagaa cttggtgata aaatcacgat caatcaaaaa ggttctgaga tcgatgaagt
    21001 gaatgagcaa gctgggatca aaccagtaaa agtttctgat gacgtctaca cgttagtcaa
    21061 gcgggcctac gaatatagcc aagattctca aggcggattc gatatggcga ttggtgcaat
    21121 cacacaatta tggcgaatcg gttttgatga cgccagaaaa ccttcccaag aagaaatcga
    21181 tcaggcattg aaattagtgg attatcataa gatcgaacta aatgacaaag aaaaaactgt
    21241 ttatctaaaa gaaaaaggaa tgatcatcga tttaggtgca atcgccaaag gttacattac
    21301 ggacgaagta gtgaaagtct tgaaaaaaca aggagtgacc actgccatcg ttgacttggg
    21361 cggtaatgtc tatgtcttag gccacagccc aagaggcgaa aaccaagact ggacagtcgg
    21421 catccaagat ccgaacatgg ctcgcggatc tgttttaggt tctattaaag aacggaacaa
    21481 aacattagtt acctctggaa tttacgagcg ttatttagaa gtagatggca aaaaatacca
    21541 tcatttgttt gatccaaaaa cgggttatcc gttcgacaat gatatcgcaa gtgtcacgat
    21601 cataacagat aaatcaattg atggtgacgg gttgtctaca gcagtctttt caatgggtgt
    21661 gaaaaaagga ctggaatacg tcgaaagcga attgaataac gggacggaag cgatcttcgt
    21721 gacaaaagac gataaagtat atgtgaccga tccaatcaaa gacaccttca aattatcgga
    21781 ggactcccat tacacgatgg gtgaccgttc tgaactaaaa taaggagtac gaaccatgac
    21841 actaaaaatc tttttagaag tagttgaaat acgaacaaag gtggctagtg tatttccttt
    21901 tgcggtaggg gtattattct ctatcgcttt ttttcatgag atacattggc taaacacttt
    21961 tttatttttt attggaatgc tagtttttga tttagcgact accgctatca ataattacat
    22021 ggattatgaa aaggctcatt ctgaagtata taagtatgaa gaaaatgtca ttggccgcag
    22081 aaatctatct cctgtattga ttcgaaacat gattttagct atgattgcat ttgtttttgt
    22141 tatcggcgtt attctaacga tcaatacggg ttggctttta cttttgatgg gatttatctg
    22201 ttgttttatt ggagtattct atacattcgg accgattcct ttatctcgaa tgcctttagg
    22261 ggaaattttc agtggggtga ctatgggcct tggaattttt gccatggtcg tttatgtcaa
    22321 tacattcggt tcagatgtct atgatctgac agtcaacttt tcatctggac aatttgattt
    22381 ggtaggaaat ctttgggcta tagcagcaat cgtattagct tccttaccct tggtgtttac
    22441 gattgccaat atcatgttgg ctaataattt gcgggatctt gaccgtgata ttgaaaatca
    22501 tcgctataca ctagtttttt atatcggacg tcctgcggga acagtcttat tccagctatt
    22561 gatgtatgct tgctatttcg tgattttaat ggggttgttg agcggtatct atgaatggcc
    22621 gatcttggtc accttcttga ccttgccaat tgtgaagaag catttggatc aattcaagca
    22681 aacgttaccc cagcctatca gtttcagcta ttccatcaaa aatatggtct tattcaatgc
    22741 cagttatgta ttggggctat tactaacaat cattatgcaa gccatttaac agcatgaaga
    22801 ggttgtgaaa aaactgccct gcatcaagta ataagaacag ccaaataaaa atagctcctt
    22861 atatttttcg tttggttggg cttattaccg cagatgcaag cttttgaaca ccgtttatca
    22921 ggaggttgtg aaaaagtcgc ttagtttcga gtattaagaa aaattttgtg aaaatggctt
    22981 tccacatttt tgcataaatt tggcttaata ccgagaaact ggcttttgaa caccgtttat
    23041 cagaggttgt aaaatcagtg ttttgtcctg agtattagag aaacaaatgg aaaaatagtt
    23101 cctcatattt tgccgttttt tgagctaata ccgaaggaca gctgattgaa cactatttgt
    23161 tcggaaaaag tgactaacta tgacacaatt tttttcacag tccctttttt cacttgattt
    23221 gattcgtacc agcgaacttg acgagaactt tcttggtttg gtaactatat ggtattcttt
    23281 taacatcctc gtttgcttct tctaatttat ttatacaaag tcacactttt ttaaacatct
    23341 gttcttcgat acatttctat ttcttttaaa catcgatacc aatattttga acttaagagt
    23401 gcataccaaa tggattcatt tactcttcgt cagttacgaa gataatcaaa atctccaact
    23461 tccctactta tttcgttttg agaattatcg aagcaatctt acataaataa ctaaaaaaca
    23521 aaaaaccaga aaatcagtat actgattttc tggttttaca tggtttgttc aataaaaagc
    23581 tgttggaact gttaatatta aattatcgca tcgttacgaa ttcttccgct cctgttggat
    23641 ggatggctac tgtattgtca aagtcttctt tagttgcacc catcttgata gccacggcaa
    23701 aaccttgcag catctcatcg acaccaacac caatagcatg taagccgacg attctttctt
    23761 cttttccgac acagatcaat ttcatttcgc atttttggcg ataatcattt aatgcaaagt
    23821 acattggggt aaagcgtgaa cgataaactt tcaattcatt ttcgccatat ttttccaatg
    23881 cttcttcttc tgtcaaacca attgttgcaa ttggtggatg cgtaaagacg actgtcggaa
    23941 caagtttata gtcaagataa gaatctttct ttccattaaa taaacgttct gataaacgtc
    24001 taccagctgc gattgcaaca ggagtcagat ctaatttacc gatcacatca ccaacagcaa
    24061 aaatatgttc atccgttgta ttttggtatt tatctacttt gataaaccct tttttgtcca
    24121 attccacatt tgtattttcc agacctaatt tttcggtatt cggtacacgt ccaccggcaa
    24181 aaagtacaca atcaccagtt aaggtttcac cattttcaaa tagcaccgta tattcgtcat
    24241 tgtttttagt aatttcttta gcaatatgat gtgcgtaagt ttttattcca gcttcttggt
    24301 acatttggat caaattgtcc gaaagcattt tatcaaacgt tctaagtggt cgttcttttc
    24361 gatatgccca catgacttca ctacctaaac cacgaaatac acctgaaagt tcagccgcaa
    24421 tgtatccagc acctaaaacg attgctctct taggtaactc tgttaattca aaaaatccat
    24481 ttgaatcaat tgcgtattct ccaccaggaa tggtcatttt acttgcacgg cctccagtag
    24541 cgatcaagat tttaggagca cgataggttt caccgtttac ttcgatcgtt tgactatcga
    24601 taaaagtagc gtaacctttt atagcctcga catgattgct atctaatcct ctttgataag
    24661 caccgtgtag aaaatcaata tatttttctc gtctttctac tagaccggcg aaatcaacat
    24721 tttttaaatc tgcttggata ccgtaacttg aggcatctcg ttcaattgtt tccaaaatcg
    24781 tacttgcttg ccacataact tttttaggta cacaaccgac gttgacacat gttccgccca
    24841 attcattcgc ttcaatcagc aaaacttttg cgccatgcat ccctgctctg tttgctgaag
    24901 caataccgcc agagccgcca ccaattacga tgtaatcata tatttgcatt ttgttcctcc
    24961 ttattgaaga gatcaatcaa aacctttatt taacgatcct ttttctacag aaaacaagtg
    25021 taacactttt cttgaatttt gtatgcgaag atgcttaaaa cagggatata tcagcttttt
    25081 ccttatttac gttttcggat catatctcca ggtttcaccg gctgtgcgac tggcatagtt
    25141 aaaatcatca ttggatttgg tgctcggtca atggattcgc cttcttcatt atgcataact
    25201 tcaacggttt gactgaaatg actgaatcct ggaccataaa attcgatttc atctcctaca
    25261 gaaaacaagt ttctctgacg tatcgtagca atctgtgttg cctcatcata agataatact
    25321 tcaccgacaa atttatatac tgggatttta cgacgttcac cgaataattg ttcgttttca
    25381 gttggtgtat tgtagtaaaa acctgtagct aattctcgtt gtgctacttt ccataactcg
    25441 tcgatccatt cttgcttgca gacatagttt tcaggatctt ccatataact gtctacagcc
    25501 gctttataga catttgacac cgtagataca taatggatcg atttcattct tccttcgatc
    25561 ttgaagctgt ctacgccgtt ttcaatcaat tctggaatat gttcgatcat tgacatatcc
    25621 actgcactca tcgagaattc ttcttccact tcgcctgtat cagttaaact gtttcgttct
    25681 tgaccaaaag gcatatcgaa caatccatac ttccagcgac aagattgaga acatccgcca
    25741 cggtttgcat cccgcatcga catatggttg gacaatgtgc atcgaccaga ataagagata
    25801 cacatggcac catggataaa tgcttcgatt tcggtatccg tatttttacg aatctctgcc
    25861 acttcctcca ttgaaacttc acgagctaaa acgacacgtt ccaacccttc ttctttccag
    25921 aattccaatg tctcaaaatt agttgctgaa gcttgagtgg ataaatggat cggcagacct
    25981 ggggcttctg tcgcacaaat ttcgatcaaa gctggatcag aaacaatcac tgcagaaata
    26041 ccgacatcac gcaaactgcg gaaaaattcc cctgctccat cttcatttcc ttcatgggtg
    26101 accatattag cagcaacgta taccttcgca tcatgttctt ttgcaaaagc aactccttca
    26161 gccatttctt cataagtaaa attacctgca cggcttctta aaccatatgc attcccgcca
    26221 atatatactg catctgctcc ataatggatc gcggttttta acttttccag tgttcctgct
    26281 ggcgctagga tttctggtcg tttcaatttt ctttttactg tcatttcttt catcatactc
    26341 cttatttgat agcagaagga tcaatataaa agaatcctgt atctaattca cggttttcag
    26401 gatgcaattt actgatttcg ctagtcattt tttccgcttt ttcttgatcc cagctacctt
    26461 ctaaaatttg tttttttgct tcggcgaata gtcgagtgat gtttacgaat ttttcgcctg
    26521 gagtaaataa tccgtccaat ttccatgtac agtaatgatg ctgataaagt tcattcaatt
    26581 cattcgagag attcagatca ttgctggcaa aaatatgtgt gccatgacta tcttcataaa
    26641 tagaataatg tgtctcttct tttttaggtt ccgagataaa aagacctctt tcacgatctt
    26701 tttgttcgtc ttgtttcgta tagttatagt aattctgtag cagtggacgt ttggattgat
    26761 ggatgcatgt agcaccatac acaagggttt ctacaggaat atcgagtttt tcttccatcg
    26821 ccttcatctc ttcaaaagga acttcacgag caagtactgc tccaactgcg ccttttttcg
    26881 cccagaaatt gatttgacgt gcgctcgtta ctaatgtttc agcatcataa atatacggta
    26941 tacgcaattc aggatttttt ttcatcgtat aaataatacc tgtatcacca actgtgatca
    27001 catctacgtt tatttctttt aaaaaagcca aatattcagg tacatttttc attttttcag
    27061 gatgaatgat cccatttaca gcaatattcg cttttttacc atacttgtgt gctaattcta
    27121 ccaattgtcg ctgttcttct cgtgtaaatg aagcaggcag acgcaatcca aattgctctt
    27181 caccgaaata tagtgtatct gcacctgcag caagcaactg ttctgcttgt tcaatagttt
    27241 ctactgtggt tatgagttcg atcataattt tctcctccta caacttcata atagtagcat
    27301 agctctaaaa actttccaat acttcttcta tttaaagtcg gatttttgaa aattatttca
    27361 caaaaaatca aaataaagtt cgatatattc tgtccaaata taaaaagaga ttgtgacaaa
    27421 aatcttgtca caacctctta atcaagtctt actattataa aaattcagct acacaggcca
    27481 agtaactata gggaacctac tgtttccttt ttaggtccgc gaacattcaa tgtgatctta
    27541 ccttttgaag cacctactgt tacgtggtca cctaaacgaa tttctccgcc aagcaaagcc
    27601 tcgctcaatc gatcttcaat ttctttttga agtgcgcgac ggattggacg tgcaccatat
    27661 tcaggatcaa atccagcttt cccgatcaca tcgattgcag atggtgtgat tttcacttga
    27721 atatcttgtt ctttcaatcg tttgataatc gctttgctca tgatttggac gattgtatgg
    27781 atttcatctt tactcaatga atggaagacg acagtctcat cgattcgatt caagaattca
    27841 ggtcggaaag ctttctttaa ctcttctaag atacgttttt gcatggcttt gtgatcttta
    27901 gtaacatctt ggacattgaa tccgacattt ttttcttctc gaatttgtgt cgctccgata
    27961 tttgaagtca taatcatgat tgtatttcta aagtccactt ttctaccttt agaatctgtt
    28021 aaatgaccat catccaatac ttgcagaagt aaattgaaaa cgtctggatg tgctttctcc
    28081 acttcatcta agagaatcac tgaatatggt ttttgacgaa ttttttctgt caactgtcca
    28141 ccttcatcat accctacgta tcctggagga gacccgatta atcggcttgt actgtatttt
    28201 tccataaatt ctgacatatc aacacggatc agggcatctt cacttccaaa catgacttct
    28261 gaaagtgctt tggccaattc tgtttttccg acaccagttg gtccaaggaa catgaatgaa
    28321 ccaattggac gatcaggatc tttcaatccg cttcgtgcac ggcggatcgc acgtgaaact
    28381 gctttgacag cctcatcttg accaacgaca cgttcatgca gaagtccttc cagttctaac
    28441 aagcgttcgc tttctttttt ctccaactgc tgtagaggga caccagtcca ctccgataca
    28501 actgtagcaa catcttcttc tgttacacga tcagaataac cttgctcctg ttttgcttca
    28561 attgcagaaa ctttttgcag ctttttacgt agtgcttttt cttgtctgcg taattgagca
    28621 gcattttcaa agtcttgttt ttggatcgct gcttcctttt cttgtactag ttcatcgatt
    28681 tctagtttga tcacagttga ttttgttaag tgatcggttt gatccaaacg gactttcgct
    28741 gctgattcat cgatcaaatc aattgcttta tcgggtagtt gacgagaagt gatataacga
    28801 acagaaagat tgactgctgc tcgtacagct tcatctgtga tctccactcc atggtgctct
    28861 tcatatcttg tacgtaatcc ttgaagaatc acttctgctt cttcaggagt tggctcatct
    28921 acttgaatgc gagcaaaacg tcgctctaat gcagaatctt tttcgatata tttttgatat
    28981 tcatctaggg tcgttgctcc gatcgtttgt aattctcctc gagctaacgc cggtttcaag
    29041 atattcgaag catcaattgc tccttctgct ccacctgcac caattaaggt atgcaattca
    29101 tcaatgaata agattacttg accatcatta tagatttcgt cgatgacctt tttcattcga
    29161 tcttcaaatt caccgcgata tttcgtacca gcaaccaaag atcccatatc aagcatcatc
    29221 aggcgctttt cttgcatgtc ttctggcact tcacctaaaa tgattttttg agctaaccct
    29281 tcagcaatgg ctgttttgcc tacaccaggt tcacccacca gtacagggtt attctttgtc
    29341 cgtcggctaa gaatctggat aagccgtttc acttctctcg aacgaccaac aactgggtcc
    29401 agcttgtttt cttttgctaa tttcgtcaaa tcacgtgcta atgaatctag cgtaggtgtt
    29461 ccttgcggtg tttgccgttt atcttgtaca tttacatttc tacgacgatt cattcctttt
    29521 ccagcagaat caccagctag ccccattttt tgtttcagaa cttgacgggc ttttgaaagg
    29581 ctgataccta agttgatcat gattcgagta gccatgatac tttcatcttt taataagctc
    29641 atcaaaatat gttctgttcc aactttttga gaaccagttt tcttcacttc gctgctagct
    29701 aaagcaaaaa cttgtttcat tcttggtgaa tatggaagaa agactccttt agggtaagaa
    29761 cggataccac cataaccaat cagatgttca atttcttcat aaatttccgt ttcattcaaa
    29821 tccatttcac gtaatacttt tccagcaatt ccattttgct cgaccactaa ggctagtaaa
    29881 acatgttctg aactaactga ttgatgtttc aaccgttttg cttcttcttg tgcaatttct
    29941 aatactgctt gggctctttc agtaaaaagt tcttccatct aatctcactt cccatcttca
    30001 taacttaaac gttccagaaa tgctcggaga atccgagcac gtgtatgatc ttcatattca
    30061 ttgaaattca atgtgttttt tgcaattgca ctcaacatca agtttccttc tttttttgta
    30121 attatttggt cttcataaag tttttgaata atagcaaaag catttttctc actgattgta
    30181 tcatcaaata actgatttat ctgctcaagt aattgttttt tatctgaaat ccttactttt
    30241 gcaattcgta tataaccacc accaccacgt ttgctttcta ctagataacc acgttggatg
    30301 gtaaaacggg tattaatcac atagttgatt tgtgaaggaa cacagttaaa gaggtctgcc
    30361 atttcaatcc ttcgaatctc gatcatttca ctattttcca gaattttctt tatatatgat
    30421 tcaattaaat ccgaggtatt ctgatgtgcc atcttattca ttccctttga ctaatattga
    30481 ccttaattat aacgaatttg ataatagaaa gaaagaagaa cgctttttgt taaataaatc
    30541 ctttagaatc aacaaaaaaa aatacggaat atactattcc gtatcgacgc gcccaagagg
    30601 agtcgaaccc ctaacctttt gatccgtagt caaacactct atccagttga gctatgggcg
    30661 catattcaat ttaaaaaaat tataaatcat ttgaaaacaa aaagcaagat aaaaaaaatc
    30721 gggaagacag gattcgaacc tgcgacccct tggtcccaaa ccaagtgctc taccaagctg
    30781 agctacttcc cgtttaaaaa ataaaaaaga c
//
LOCUS       DACDLM010000030        29782 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.030, whole genome shotgun sequence.
ACCESSION   DACDLM010000030 DACDLM010000000
VERSION     DACDLM010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29782
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.030"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(594..1985)
                     /locus_tag="IV356_001415"
     CDS             complement(594..1985)
                     /locus_tag="IV356_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HAP9015107.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAVAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            complement(2198..2584)
                     /locus_tag="IV356_001416"
     CDS             complement(2198..2584)
                     /locus_tag="IV356_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HAP9015108.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            complement(2640..3263)
                     /locus_tag="IV356_001417"
     CDS             complement(2640..3263)
                     /locus_tag="IV356_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HAP9015109.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            complement(3327..3995)
                     /locus_tag="IV356_001418"
     CDS             complement(3327..3995)
                     /locus_tag="IV356_001418"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAP9015110.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            complement(4007..4447)
                     /locus_tag="IV356_001419"
     CDS             complement(4007..4447)
                     /locus_tag="IV356_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015111.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            complement(4506..5177)
                     /locus_tag="IV356_001420"
     CDS             complement(4506..5177)
                     /locus_tag="IV356_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015112.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFLPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            complement(5362..5760)
                     /locus_tag="IV356_001421"
     CDS             complement(5362..5760)
                     /locus_tag="IV356_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HAP9015113.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(5757..6530)
                     /locus_tag="IV356_001422"
     CDS             complement(5757..6530)
                     /locus_tag="IV356_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HAP9015114.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(6527..7210)
                     /locus_tag="IV356_001423"
     CDS             complement(6527..7210)
                     /locus_tag="IV356_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HAP9015115.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(7377..8264)
                     /locus_tag="IV356_001424"
     CDS             complement(7377..8264)
                     /locus_tag="IV356_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP9015116.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(8261..9130)
                     /locus_tag="IV356_001425"
     CDS             complement(8261..9130)
                     /locus_tag="IV356_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP9015117.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(9267..10553)
                     /locus_tag="IV356_001426"
     CDS             complement(9267..10553)
                     /locus_tag="IV356_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP9015118.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            10826..11404
                     /locus_tag="IV356_001427"
     CDS             10826..11404
                     /locus_tag="IV356_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAP9015119.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            11404..12333
                     /locus_tag="IV356_001428"
     CDS             11404..12333
                     /locus_tag="IV356_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP9015120.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            12330..14066
                     /locus_tag="IV356_001429"
     CDS             12330..14066
                     /locus_tag="IV356_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP9015121.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(14129..14965)
                     /gene="pheA"
                     /locus_tag="IV356_001430"
     CDS             complement(14129..14965)
                     /gene="pheA"
                     /locus_tag="IV356_001430"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HAP9015122.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(14962..15471)
                     /locus_tag="IV356_001431"
     CDS             complement(14962..15471)
                     /locus_tag="IV356_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HAP9015123.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(15464..16759)
                     /gene="aroA"
                     /locus_tag="IV356_001432"
     CDS             complement(15464..16759)
                     /gene="aroA"
                     /locus_tag="IV356_001432"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HAP9015124.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(16772..17863)
                     /locus_tag="IV356_001433"
     CDS             complement(16772..17863)
                     /locus_tag="IV356_001433"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HAP9015125.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(17880..19046)
                     /gene="aroC"
                     /locus_tag="IV356_001434"
     CDS             complement(17880..19046)
                     /gene="aroC"
                     /locus_tag="IV356_001434"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HAP9015126.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(19048..20112)
                     /gene="aroB"
                     /locus_tag="IV356_001435"
     CDS             complement(19048..20112)
                     /gene="aroB"
                     /locus_tag="IV356_001435"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HAP9015127.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(20145..21167)
                     /gene="aroF"
                     /locus_tag="IV356_001436"
     CDS             complement(20145..21167)
                     /gene="aroF"
                     /locus_tag="IV356_001436"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HAP9015128.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(21826..22800)
                     /locus_tag="IV356_001437"
     CDS             complement(21826..22800)
                     /locus_tag="IV356_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HAP9015129.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(22781..24664)
                     /locus_tag="IV356_001438"
     CDS             complement(22781..24664)
                     /locus_tag="IV356_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HAP9015130.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(24682..26907)
                     /locus_tag="IV356_001439"
     CDS             complement(24682..26907)
                     /locus_tag="IV356_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAP9015131.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            27022..28056
                     /locus_tag="IV356_001440"
     CDS             27022..28056
                     /locus_tag="IV356_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP9015132.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(28123..29136)
                     /locus_tag="IV356_001441"
     CDS             complement(28123..29136)
                     /locus_tag="IV356_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP9015133.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(29214..29402)
                     /locus_tag="IV356_001442"
     CDS             complement(29214..29402)
                     /locus_tag="IV356_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HAP9015134.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
BASE COUNT         8582 a         6436 c         5257 g         9507 t
ORIGIN      
        1 atctgttcta acattctcaa ctttgtcagt ttaccatagg aaaatgggaa aatctacgaa
       61 agctctcaac agaatcgtcc tacttaaata cgcttttctt taataataaa taagttggtt
      121 gtttttgtta tttgcgcttt cacttttcgg aataaataat gtgtatttat atggaataaa
      181 taaaaaaaga ggtcgtgact aaaaacaagt cacaacctct ggtaaacggt gttctcctga
      241 caactcctcg gtcacaagac acaatattca acaaacatga gaagctattt tttgaaattg
      301 ctctttgtga ctcagagtga aacggcaggc tcacgacctc tttcttaaac ggtgttcaaa
      361 agcttgcatc tgcggtaata agctcaacca aacgtaaaat atgaggaact atttttgttt
      421 ggctgttctt attacttgat gcagggcagc tttttcacaa cctcttattc acggtgtttc
      481 agaagtagct tctcggaaat aagccgaaat ttcacaaaaa tttgagaaac tatttttagg
      541 aaacttcttc ttatttctta aagctgacca cttctatcac aacctctttt tgactatgca
      601 ttcacatcga tcactttaga atcatcattg atgacatcgc gatctaaatc tttgatgcgt
      661 gcacttgtca cgataccagc taccatgcta ccgctgacgt ttactgctgt acgtgccata
      721 tcgattaatg gttcaacaga gataactaac ccaacgattg ctactggcaa gttcattgcc
      781 cctaaaacga tcagtgaagc aaatgttgcg cccccaccga ctccagctac accaaaagaa
      841 ctgattgtta caattgccac aagcatcaaa ataaattcca aactaaagac attcactcca
      901 gctgctggtg cgacgatcgt tgccaacata gctggataaa cgccagcaca gccgttttgt
      961 ccaatagaca aaccaaaact tgctgagaaa ttagctgttg catcatctac tcctaaagct
     1021 tttgtctgag tctcgatatt caatggcaaa gctccagcac ttgaacgtga agtaaacgca
     1081 aagctcaata ccggaaaggc ttttttgaaa tagttgattg gattgacttt tgcaccaatc
     1141 aaaatcagtg agtggacaat caaaacagca agcaatgcta cgtaagaagc aacgacaaat
     1201 ttacctaaat tgacgatagc tgcaaaatca cttgttgcca aaacgtttgt catcaaagca
     1261 aatactccat aaggtgtcaa acgcaaaaca agcgtcacga tccgcataat gattttatac
     1321 agactgtcga ctaaatctga aaagaatgct gcttcttttg gcgcttttct tttcacgcct
     1381 agataagcga ttccgacaaa tgccgcgaaa ataacgactc caatcgtact tgttgcacga
     1441 ctacctgcta aatcagcaaa aacgttttta gggataaagg ataaaatctg ctgtggaatc
     1501 gataagtttt caactgtttc ctgacgtgtt gccagttcag agattcgtgc tgtttctgca
     1561 gctccttgtg tgaatttagc tccttggagt ccgaacagca ttgttgaacc aattccgatc
     1621 aatgctgcaa cagctgttgt tccaagtaaa gaagtcaata cagtcgcact aattttccct
     1681 agcttttcag aaactttcat ttttgtgaat gcaccaatga tcgaaataaa cactaaaggc
     1741 ataactagca tttgcaagaa tgatacatat ccttgaccta caatcccgat ccattccatt
     1801 gattgagtaa cgactttgtc gtctacacca aagatcaatt gaagcagacc gccaaagacg
     1861 ataccaactc ctaatgctgt aaagacgcgt gttgaaaatt ttgtatggcg cttttgcata
     1921 cgatagaaca catataataa tgccgcaaaa actagaacca ctaaaactgt gatgagtgtt
     1981 gtcatttttc tcctcctcat attattaatg acaagtccat cgaaggaagt aaaggttccc
     2041 gagaatgatt cttcaaccat cctcctgaaa aaattttttt cagtgacttt tatattttag
     2101 acgattttta tcgaaatgac attctttttg cttacaatta gtaataaaaa aacatacctg
     2161 tgatagcttt aatctatcgc aggtatgttt ttactgtcta ttcttgtttt tctgattgaa
     2221 aattcaattt taccccaggc tgatctaagg cgatctctgt cacctcataa gacattcggc
     2281 gtacgatatc gaataacggt gctactagct cgtccacttc ttcttgtgtg acatcatttt
     2341 gaccttcaat tttccgattg aggatatgat tgatctgact cacacttcca gataaaacat
     2401 atgtatcaaa cactaaacgg aactctaagc gtgctcctac gatgctatgt tctttcggat
     2461 agttttcgat cgtttctttt aaaggcgaga agcctacttt caaatctgtt tctacttctt
     2521 ggttcggcaa tctcatatca taatgaaatg cttctacaac ttctttttgt cttctgattt
     2581 ccatataatt ttatcactcc tttatgaaaa ttataacata tctcctttga aaggggatac
     2641 tactttttaa tgatgctctg caaggtaagg atttcattca gatttcctac cacataatct
     2701 gccgggatct cacccagaaa atgatcgatg tcgtaaagac aagtagcgac tcctgcattt
     2761 ttccctgctt cgatatctaa acgacgatcg ccgatcatca tcgtgtctgt tctttctaaa
     2821 tgaaaagtat cgatcaaata atttaaagat gctggatcag gtttacgagg aaagtcctga
     2881 tcgatcccta ctacttcctc aatcagatgt gccaatcgat gttcttttaa caggccccat
     2941 gttgattctg tcaaacggtg ggtcaggatg aaatgacgac cgccgttgtc ttttagcatt
     3001 tccagtactt gtttcgtttc tggaaatgga cgggaaactt ccgtactttc tttttcatat
     3061 cggtgaaata attcattaaa ctctctggca ttcaagtttg attcattgat caaataacta
     3121 gtagaatact ttttcatttt gaagtagatt tcttttttgt ccatactgat accaaaatct
     3181 tttagtgctt gccatgcacc atctaccatt gcgggatacg tatcaaacaa tgtaccatca
     3241 aagtcccata tataattttt catgttcctt ttgttccatt cctttgcttc ttttttctat
     3301 ctctcacttt tagataaagg tgttctttaa agtatttttt tgtccagaat tgtcaaatca
     3361 tctgctaatg tatactggat tggttgtgca tttgggatat cgatcgtatc catttgatct
     3421 tcaggaacat cttctaaata ttttgtcagt gctcggatgc tattaccatg acccacaact
     3481 agtaaatctt gccgatcttt tagttttggt gctagatgat cttgccataa gggaatgatc
     3541 cgattcactg tcatttccag actttctccg tatgggatca aatgcggatc caagtgatca
     3601 tatctgcggt caaatctatt ttctgcggtt aacggcggaa cttccgtata tcctctgcgc
     3661 catgttttta cttgatcttt tccgtatatt tctttcatct tatctttgtt tttacccaca
     3721 agatccccat aatgccgttc atttagacgc catgttttta ttataggaag ccataactga
     3781 cccatttctt ctagtgcgac ttgtccggta agaatcgcac gtttcaaaac agaggtataa
     3841 acggcatcga attgaagtcc ggcttcaagc attttttgac cggcaactgc tgcttgttct
     3901 tttccttttt ctgttaaggc gacatctagc catcctgtcc agtaattttc aaaatttgct
     3961 tcgctttcgc catgacgtaa taatactaat ttcattcttt tctcccttaa acattcgttt
     4021 cgaattttat accacatgtt ttgcatgtca cacgtattcg tccttttcct ttaggtgcac
     4081 gctgcttttg atgacaattc gggcactcaa aaaaagtata actttttcga tccattttga
     4141 cttgcttttt gttttttatc tgatgatatt tttctttgac tctatcaaga tatttcaaat
     4201 aacgttgatt ctcatttagt ctggggtaga ttttttttga taggaaacga aatatcatcc
     4261 atccgaaaaa gacgatgaac aacaattgtc cgattctata gggcaaccaa cgacttagca
     4321 aactaaagac aagcgcagcg atcaatagac cgcgattcaa ctgatcaaat ttcgcatatc
     4381 ttccctgcat aagtttgtga tagttctgct gaaatcgtat tagcctttct aaccatgttt
     4441 gcatcatatt atctcctcca tcatctaata tttattatga caaaaaaatc caaaaagaaa
     4501 aagccttaat tggccttttc cattgcaact tggtgaagga cattccgatt tctggtaaag
     4561 tcaatcacaa tcactttctt tttatcttct ctgttgacta ctcgaaatgt gtccgtcaat
     4621 ggaagaaaca gcttcttaga tggtagctgt tgcatacgta taaaacgatg gatcatcgta
     4681 atcaattgag gaaattgaat agacgtgtga agcagacctg gatatttttt caacagctgt
     4741 gtcgttttga tcagattccg ttttttactg atcactttta aaaagctttt tagaatcttt
     4801 tgctgacgtc taaaaataga aaaagaattt tcgtcatcta tttgataacg catttgtttt
     4861 tgcagttctg ctgcagtcag atggatcttc ccatcgtttg tatcgatcat taaaccttct
     4921 ggaaacagtt caaccactgc tcgatcccaa gattcaagag aaagctcgat ataatctttt
     4981 actggtaatt ccaattctac cttaaaaaag tgcaaaacag ccgacagccc ttctgcttga
     5041 tagatttctc ctaatgttag cccctctaga tggaactctg gtaaaaaatg cagcaatgtt
     5101 ttattttcct gcaattgaac atatagaaat gtagatcgct caatcagagt atcttttaaa
     5161 acaactaaaa aattcatttt tctccccctt ttttcatcat ttttaaaata gcatattttg
     5221 aaaagaaagt ctgatgctta gagtagaatt tcataaaaat ttactatttc ataagtattc
     5281 acgagaaaaa tacaaacaaa aaagcggaaa taacgctcat ccgccttctt gtttgtgttt
     5341 atttcctctt caaacgcttg tctatgattc agacttttct ctatcgttat tttcatctaa
     5401 aagttcttgc attccgataa tttctcgata ttgatgaatc ttagtgatac caatgacttt
     5461 gtctacatca atactaaaac aaataccatt acctggaata tcgatgttga tgccttgacc
     5521 aatcgcatcc attactttat tcgtcaaact atcgggtact aatgtcaaca caatatcttt
     5581 ttctggcgaa atgtccaaac ctaaaaattt ccctgaatca tgtacaccag aacctcttcc
     5641 atgtaagatc gttccgcctg ctgcacctgc ttcttttgaa aagtcgataa catcttcgcc
     5701 cattcctccg tcaacgatcg tcacaatcat gtgaagattc aatgctacaa gatctttcat
     5761 ttgctttccc ccaatttttg caatctttct ttttcgattc tgtctttttc atcttttcgt
     5821 ttataaatat atcctagtac taaagtggat aatattggtg tcaatgcaat cattgcaacc
     5881 acaccaaacc cgtcaatgat cggatctctt ccttcaattt gtgcagcgat tgccacgctc
     5941 attgataaaa taaatgtcga acacatcggg cccgttgcta ctccaccgtt atcaaaagcc
     6001 attgctaaaa agatcttgtc cacttttcgt cctaaaataa atgctagccc gtatcctggg
     6061 atcaagaaat aataaagaga gaatccgacg agcaaacgcc acatagacaa tcctactgct
     6121 gcgccgatcc caattgaaat taccatcagc atgattttcg atcggattct cccctcgctc
     6181 aattcttcaa cctgtttgat cattacatga atcgccggct cagcaaaccc tactaagaac
     6241 cccattaaaa agccaagggg aaccagtata taattgtaag gcaatcccgc aatagcactg
     6301 cctaaatgct gtcctaccgg tacataagcc atattgactc cgtgcaggaa aaggatcaac
     6361 ccaatagtcg ttatcaagaa acctttcata atgtcaaaga aacgcttttt gcgcatacga
     6421 aaactaatga tattcattaa aacaaatagg attacgatag gtgccactgc caaaatgact
     6481 tccatggtaa cgatttcgat tccatctatc acttgctgcc agaaactcat tggaagatca
     6541 cccccaaaat catcacggca agaatcggcc ctaacgaagc aataccgacc attccaaaac
     6601 tgtcattttc atttttcttt tgtttgatca tactagtcat ccctccggca agggccaaga
     6661 taaatggaac agttactgga ccagtagtca ctccccccga atcaaaagca atcggcataa
     6721 attcggaact ggtgaaaaat gaggcgatca aaacgcctat gtagcctata gccatcaatt
     6781 gataatagga tagcttgaat acgacccgaa gcagcgcaaa ggctagaaat actccagtgc
     6841 cgacgctgac gatcccaatc agcaacactc tgccaatctc tccgtcagat atatcatata
     6901 cttgttgtcc caaaacttgc acggaaggtt cagcaatcgt gatcacgatc ccgatagcaa
     6961 atcccaaact gaccaaaacg gtcaaacttt tctttttgat catatatttc cctactagat
     7021 ctccgacttc catcatagaa taatctgctc caaacaaaaa gagcgtcatt ccgatcatca
     7081 tgattgccgc accaaccaga aatgaagcga ggtcttctcc ttctaacggt gcaaaaacaa
     7141 acgttaaaat gacaatcagg acagtcatcg gcaatatagc agcaatcact tctttaaaat
     7201 tttttagcat gtatcctcct cctttactct ttaagtttac cttaaaatga aagagttttc
     7261 gagcacaaac ttaaaacgtt atcatttaat ttttctcaac ataaaataac acacgtccca
     7321 aaagtatctt tttacttgga aaaatgactt tgaaggaacg cgcttattgt gtttttttat
     7381 tttacagagc cgatcattcc ttgaacgaat tgcttttgca aaacaaaaaa tacgatggca
     7441 gttggtaaag tagcgatgac taatccagcc atgatcattc catagtctgg tgtataggaa
     7501 gcacccatag cagataaaac aagcggaacc gtccgtttat caggagattg caaagctact
     7561 aagggccata aataattgtt ccagctactc atgaatgtga tgattgcagc cgcggcatag
     7621 gtatttttag ccgtcggcat atacactcta aaaaaaatac ttagttcttt tagaccgtct
     7681 aatcgagcgg cttctactag atcttttgga aaagatttaa cattttgtcg aaagaagaag
     7741 atcaaaaaag cagtgctaac agatggcagg atgacaacca agaaactgtt gattcccaaa
     7801 accgttccgt tcaattgtga aaacattcga tataaaggga tcatcaatgc cgcaaaagga
     7861 accatcatcg atagcagtag aatattgaaa attaggtctt ttcgtttact ttgataaatc
     7921 tcaaatccat atcctgccat tgacgaaatc agcaatgcaa acacagtggt caccaaagcg
     7981 atcatcgctg aattccaaag ggaacgagta aaattcagct cattggaaaa caaattttga
     8041 aaattgatga tcaagttact gccaatcttt atttttcccg atgtgatatc cacgggtgta
     8101 ttcgtcattc ccaaaaccat ccagacaaaa gggaaaatgg aaataaatga taggatgctt
     8161 aatgctgtat actttaatac tgacccaatt gtcgaacgaa gttctaatgc ttgttttttg
     8221 acgttggggc gttcgattgt ttctttttct accatatttt tcatcgactt tctcctccta
     8281 ctttcgtttg gattatcgac aatatcacaa taaaggaaac aataacaaag gaaactgctg
     8341 ccgcatatcc aaaattaggc gtgaatttat aactcaaatt atagatgtat tgagataggg
     8401 tggtcgttgc atttgctggt cccccgccag taatattttg tacttcatca aaaagctgca
     8461 atgtcccgat cgtcgaagta atggaagtaa acaaaatgat tggttttaaa tttgggatcg
     8521 tcactttgat aaactgctgc catttagaag caccgtcaat agatgctgct tcataaatct
     8581 ccgaatcaat attttgcatg cctgaaagga aaaaaatcat attgtatcca gtccaacgcc
     8641 aagtgatcga aagaatgatc agaactctcg cccaaattgg atgagtcaac cagccaatcg
     8701 gtgtgtcaat cataccaatg cccaacaaca agttgtttac aaggccagat tgagaaaata
     8761 gacttttcat gatcagagaa taactgacca tcgaagtgat acatggaaga aagatagcgg
     8821 ttcgaaacaa ccctttatat ttcaactttt tatcatttaa aaggttggaa ataaaaagtg
     8881 ctagaaacaa catgatcggt acttgtacaa gtaaatacag gaatgtatta aaaaaagctt
     8941 ttttaaaagt tgcatctgtc aacatccgct gataattacc taacccgtta aatgtcatat
     9001 tgacaggggg accactttga aaagacgtga tcaaagccaa aaccatcgga ataaaaacca
     9061 tgattgatat caaaatgact ggcaagatta aaaaagcatg cccgtttttg aataaatctt
     9121 tctgcttcat tcttttccct ccaattctat cattgattat ctacatgaaa agacaagaaa
     9181 gacaatatct gtaaggcaga cgtgatcttt tttgtctttt cgtttgtctg atgaaaaagc
     9241 gaagaaattc acttttttac caccgatcaa ttagccaatt gtgcttctac ttgtttttgt
     9301 gtatctgcta gtaccttgtc tgtctcttct ccattgatga ttcgatgaag agcttcagct
     9361 acgactgctt caattgcata ggtctcatgt ccgtaattca cttctggtat ttcagatgtc
     9421 catgttgaaa aatcgtcaaa gatcttttga ccactgtaaa attcagaagc ttcttgataa
     9481 gcttcttgtt cattcgcgct aagcatcgta gatactagtc cgatttcttt cgcaagagtg
     9541 cccatcagtt cttcattcga agcaaacgtt gcttctagga aatctttcgc tgaatcttct
     9601 ccagctactc ctttgatcac ataccagcca gcgccgccaa ggttagaagc ttgcgctttt
     9661 tgcagatttt ctggaagtgc aggtattggt gcaatcttcc attttccaga ttggttttct
     9721 gctccttgga tcgttgaaga ataccaagcg ccagttgggc tagaagctac tgctcctgat
     9781 tgtatcgcag ttactccagc attccagtca gaggtttgtt cgactagatc ttctttcaaa
     9841 agagtggcaa acaattcaag accatacttt aaagatgcat tgtcttggat cgtgactgtc
     9901 tccccatctt cagatgtata ccattctcct gcctgttgca taatcatcct tactcgacca
     9961 aggtcagaag gattgacttc agcgattttc tttcccgtct tttctttgac atctcgcgct
    10021 acttgaatat actcgtccca cttcagattc tccatatcct cttctgtata acctgcttct
    10081 gccatcagat ccgtacgata gaagtttgct gttacgcccg aatcgaaagg aacaccgtat
    10141 attttatctc ctactttgtt taccgcaaat ttatacggtg caaaatgatc ttcctttaca
    10201 atagcagaca aattagcgaa tgcatctgga taagaagtca aatagccttg tatcctataa
    10261 tcttcaatca agacgatatt gggcaatcct tctgtattcc cgctcgctaa agcggtgttc
    10321 agtttctgaa cgatatcatc ctgagacatc gtaacaactt ctatctctgt ttcttcgttc
    10381 tcataaactt tttttgcttc attcactgct ttgatattga atgtctcatc ccacgcccag
    10441 acagtgactt tttcttcttt gtctgctgta ctactagcac ttccgcatcc tgttaagaaa
    10501 cctgatgctg ccgctaaaca aacgactcca gcaattaact ttctgatgtt catttttatc
    10561 cgctcctttt ccatccatta gttgtttacg tttgctacat tcatcatacc aaaatttgaa
    10621 aacggtttct ttattattca gatacttcaa aaatttctcc taaaataata aaaaaataca
    10681 aatcaactat gacaaaagga ataatcttag catctagacc aaagatcgaa atggtgaggt
    10741 ttctttaaaa taaaaatatc cttgcatttt ctcctagaaa taagtatttt taaattacaa
    10801 gactattctt aaggcgggta aaaaaatgcc aatacgcgta attcttatcg atgatgaaca
    10861 gacgatttta gatggaatga aacagttgat caattggtct gagcacgggt ttcaattaat
    10921 agggactttt tccagtccgc tgaaagcgct tgatttttct ttggtacatg caatcgatat
    10981 cgtggtcaca gatgtaatga tgcctgaatt aaatggaatc gaattatcgc ggctattaaa
    11041 acagcaacaa cctgaaacac agatccttat cctctctagc tatgatgaat ttgatatggt
    11101 taaagattct tttaaagaag gcgtcgctga ttatctttta aagcctcgat tgagtcctga
    11161 tttttttcta aattccttaa ctgccgtttc acaaaaaatc aaaaaaaagc ccaacaaaag
    11221 cccaatcacc aatcgttatg agcagatctg cgagaatctt tcacagcaga ttgctggaca
    11281 aactcgtcca ttgcttgacc ctcttctttt tgaacacacc ttgtttttct gttatatacc
    11341 gaaaaacggc cattcagttc aaaacaaggc tctaaacaaa aacagtcgat cacccattca
    11401 ttgatggata gcgacgattc gtttactatt tatcctgttt ctaccttttc ggaagaatcc
    11461 ggctatgtaa tcaatactga ttccaaagat acacttagga agtttgttca aaagtttcgt
    11521 caagaagttt ttccaggtga tttttttgtt gtttctgatt cttttgcaat ccaagatatc
    11581 aatgaaatat tccaagagat cagaaattgc accaaaggac aacgtttcta tcataaggga
    11641 aagaaccttg cttatcagca tgaacttctt ccgttattaa ccaaccacga gcagcaagca
    11701 agtagttatt taacaaaaat cgttcataaa gactacgctt tagctgtcaa agaacttgag
    11761 aatttcttca cgacgatatt ggaacagcct attgatccag cttatttgaa acatgaggca
    11821 atcaatcgtt tctatgcatt actcaacgct ttggctgacg agcatgttgg gaatgaagaa
    11881 ctttctttgc tcaagatcgc ccttccttct ttattagccg atgctgagta tttcgaagat
    11941 ttttctattc ttgtcaaaga aacacttgag aaactcaccc acttttctgc aaatgcaaaa
    12001 aaagacaatt tcgatatctt gactttgatc tacgagttcg tccaggaaaa ttatgagaaa
    12061 gaaatcaatt tacaactttt atccgaaaaa tatcattttt catatagcta tctctcagcc
    12121 atctttactg aaaaatttgg tatcaacttt tcaaaatatc taaaaaaagt ccgtatcagt
    12181 aaagccaagc tctttttgac ggaaacacgg cttactttga cggaaatctg tgagaaagtc
    12241 ggctataccg aactgggtta tttctccaga gtttttaaag aagagacagg aatgacacct
    12301 tctcaatacc gtaaaggaac ttttgtaaaa tgagaaaaaa aatcaaagag catgaactct
    12361 ttgccaaact tctgttcatt ttgttcatcg gtctttttct gcaagccatc gtcatttctt
    12421 tgtttattta tcatcgatca agggatgcct atatccagct gttcaatcaa tcgaatgatg
    12481 tggtactaaa aaagattcaa tctgaatttg aaagtttgaa tgatacaatc gagaatacat
    12541 tagccgcttt tgattctaat ccagctgtca aaagctattt ttccaatgat ccagcccaac
    12601 atatggaaca gcttcagcaa ctaagaacaa tccaaaaaat gaatgactct ctttcaaaaa
    12661 tccatccaat gatcgattac gatgtattga tctttggaga aaatggaaga acttttgtcg
    12721 gaaacgacat gctcactgcc gtatctgccg attctttttt tcaatctgcg attgctcaga
    12781 gagtgaatga acgtgctgct gatacacaaa tgctttttgc acaccacgga ttgactcttc
    12841 gcgataagaa agcacccagc gtcttctttg tcaaaaaact gaaaaataca ttgaatcacg
    12901 tttacggata tgctgtttta tcgatctcat ccaagcaact agcgaatctt tttcaatctg
    12961 tagtaaatcc tgagatatcg aagatctcct tcatgaacga agaacagacg atcatcgcat
    13021 caaatgaaga aaatacaatt gggagccgat caatgatttt caaaaaacta acagtaggtg
    13081 aaacaacgat ttcaaatgga cagcagttga cccgtcttcc tctgtaccgc caggattgta
    13141 cattactcag tcaagtcgat cttcattctt tatctaacca aatgggcgtg atttttccga
    13201 ttattttgta taatatcgtg acacttgctt ttgctggctc attggtattt atgtatttgg
    13261 atcgacacac aaaatcgatc taccgcttga ttgattcgct aaaacggcta gaggaagatg
    13321 gcttaaaagc tactgttcct gtacaaggaa gccatgaagt ccaattgcta gggaatacga
    13381 tcaatcaatt gctaagtaat gctcagcatc attatgaaca gacgatccaa gacgaaaaga
    13441 agaaacgttc gcttgaaatc caaactatgc aagcacagat acagccccat tttatttata
    13501 atacgctgac tagcttgaaa tttttgattt ggcagaaaaa aacagatgaa gcagttcaag
    13561 gaatcgacag tttcattact ttactaagaa gtacgattgg gaaaaaagaa gaagtgattc
    13621 cagtcaagga agaaatcaaa agcgtacaaa gttacatcga tcttttgagt atgcgatatg
    13681 gcgaaagaat ctcggctaaa ataatgattc ctgatgaact gcagtcatta tctatgccga
    13741 atatgatcct tcaaccaatt atcgaaaacg cctatcttca tgcttttcac aataaaacgc
    13801 aaggattcat cacggtgtac ggcaaaacaa aaaatcagct tcttttattc gaagtgattg
    13861 ataacggcga tggcttcgat actgaaaata ccaaacaaaa aaatgatcat ttttcaggaa
    13921 tcggcatcag ccatgtagat gagcggatac gcctaatgta tggcgatgca tatggcttaa
    13981 cgatccaatc agtgattggg acaggaacga ctgtaacgat ttgtctaccg cttcttccta
    14041 aaaatcaatc agaatatcaa aaataaagaa tagccaagcg ctgatttttt tattttaagt
    14101 taaataaatc aatcagtatt cttgactttc atctacgcgt ctcttctact gtcagcactg
    14161 gataacagcc caatatttga ctttctcctc cgagcatctt gatttcttgg agcgcattct
    14221 ctactaatgt cattggacgg tccaacaaca aatcgatcac gaaaaaatat tctcccaagc
    14281 tagttttcaa tggtcgggat tcaatcttac ttaagttgat ttcccgccag ccaaaagctg
    14341 ccagcatttt atgaagcatc cctggccgat tagcaggtag tgtcaagatg acactcattt
    14401 ttactggagc tgactgctgg ctggtcatct ttcggtcacc gacgatccaa aaacgtgtct
    14461 ggttcaactc attatcttgg atattctcag ctaagatctc caatccaaca tgctgtgctg
    14521 tttctaatga agcaatcgct gctgcgtctt ctttcggatg ttctgctaca tacattgctg
    14581 cagcagttgt tgattctgtt gctactaaag gaacattagg ataatgcgtt tctaaaaact
    14641 gttgtgattg tgctagtgct tgtggatgtg aaaggatttt tgtaatcttt gttgctggat
    14701 tgcctaaaag ctgctgcttg ataggaagaa cgatttcact tttaacttcg acttctggat
    14761 gtttggaaag aagatcgatt gtgtgatgaa cagctccttc caatgaattc tctacaggaa
    14821 cgacagccag atcgacttgt ttgcgaaaca aagcgcgcaa acaaacaggg atggaagcat
    14881 acgcagtcaa ttgttctgta ggaaatagct gacaagccgc ctgataagtg aatgaacttt
    14941 ctggccctag atagctgacg ttcatatgct tttgatcctt tctataatgg tatcgatgat
    15001 cttttctggt gtttgattgg tcgtgttgat tcgatgtgtc gcactttctt cataccaaga
    15061 aagtcgttgt gccaataatg cttttatttc ttctcttgtt tttccaagag ctaaaggtcg
    15121 aatagacgtt tcatcttgtt ggatacgatc aactagacag tccgcttctg cctctaagta
    15181 aagaacaatc ggctgtgttt ttaaaaaacg ccgattttct gcactttgga caatccctcc
    15241 accagtcgcg ataattttgt cttcatttga cagctttctt aaaatatctg actccacttt
    15301 tcgaaagctt ttttcaccgt aatagtgaaa atattcggca atcgacaatt ggatatgttc
    15361 ctcaatcttt gtatctaaat ctacatactc tttttgtaaa cattgagcta accctttacc
    15421 gattgttgtt tttccagcgc ccatgaaacc aatcagcaaa atgctagcca tgagcttctc
    15481 ctcctgacac aagttctgct aaatcgtcaa aaaatgccgg ataagagatt gaaacagctt
    15541 cagctccttc tagttcgcaa ggtccatcag ctatcaaagc agctacttgc agcatcatac
    15601 cgattcgatg atcgcctctg ctggacactt ttgcgccatg cagaggtgtc ggcccatgga
    15661 tgatcagacc gtctgctgtc gcttttatct ttgctcccat tttctgtaat tcttctgcca
    15721 ccgcatcaat tctgttggtt tcttttactt ttaattcttc tgcgtctttg atgatcgtga
    15781 ttccttctgc ttgagtagcc actaaagcta gaatgggcaa ttcatcaatc agacgcggaa
    15841 tgatttctcc accaatcgtt gctttcttca aatgactcgt cttgacactt aaatcagccg
    15901 attggttctg ttcattgtga ttcgtctggg taatcgctgc gcccatctcc tccaacacat
    15961 ctaagatacc agttcttgtt ggattgaccc cgacattttt taacaacagt tggctttccg
    16021 gaacaagaag tcctgctgct agaaagaaag cagctgatga aatatcacct ggaacagtta
    16081 tctgttgacc agttaatttt tgcggtccgg tcactatgat cgttttatct tccactgtga
    16141 tccttccgcc aaattgacga atcatttctt ccgtatggtt acgggaacgt tctttttcaa
    16201 cgattacgga tgtgccttct gcttgtaatg ccgcaaacag caaagcagat ttgacttgcg
    16261 cactggctac aggcatattg tatcggatag gtgataaaga gcgggttcct gtcacagtga
    16321 ttggtagata ctggtcattt tcttctcctt gcaagtcagc gcccatctcg cgtaaaggtt
    16381 ccatcactcg ccccattgga cgtttagaca acgaagcatc cccgaacaga gtagtcgtaa
    16441 aaggctgtcc agccaaaata cccatcaata aacgtatggt cgtaccggag tttcccatgt
    16501 caattgattc ggttggttgg acaaatgagt ggctaccgcg accatgaatc ttgatcacct
    16561 cttcctcttc ttcgatctcg acacctaatt gttggaaggc atgtaaagta ctcagacaat
    16621 cttctgcgcg caaaaaattt tgtatagtcg tcgttccttc agcaattgct ccaaacatga
    16681 tgctgcgatg ggaaattgat ttatctgctg gtatcctaac agtccctctt aatccatgta
    16741 tttgttgtaa taattgcatt tatccagcct cctatttgat ccagcaatga taactggtat
    16801 tagacataat gattcttttt gcttgtaaca aatcctgttg gtttttaaaa ctgatttgca
    16861 gtattcctaa aatatcttcc ctggtctctt ggatcttcaa attaatcaaa gaaactcccg
    16921 cttttccgat cagtccagtt acttctgcaa taacgccagg ttcatctggc acatcgataa
    16981 ataaatcaaa aaaggcagga atcgcgcctt gcttatggac aggcaactgg tctcgacttt
    17041 cttttgcccg attgaaaaaa gaaaagattt ccgattggtt ctcagtcatg atccattctg
    17101 ctatttgtgt catttcttgt tgccaatctg ccaatcgttc caataatatc tgcttattgc
    17161 tcaacaaaat atctgtccac atgacaggat ctgaggaagc gatcctagtg atatctcgaa
    17221 agcctcctgc tgccagttgt ttggctcgcg gatactcttg attgaattgt tctgcctgat
    17281 tgactaagcc agctgccaga atatgtggaa aatgacttag cattcctgtt atacggtcat
    17341 gttctcttgc tgtaagagtt acatattttg ctttggttcc gcaaaatagt tcttgcagtt
    17401 tttcaacatc ttttttcgtc ttttccaaag gtgtaaagat gtaataggca ttttcaaata
    17461 gtttagcatc tgctgcctgt atacctgatt tatgagaacc agccattgga tgtccaccga
    17521 caaaccgaag atttttctgc tcagcggatg tcacgacttg ctgcttcgta ctgctgacat
    17581 ccgtaatgat gacgtgatca gacaagttga ttctttcaag gacatcaaga taagctaagg
    17641 ttgtacggac gggaacggct aataagataa cgtctgcttg ttctgcacct gtttcaaaat
    17701 cacttgcaac gtaatcaacg atctgctgtt ctactgcttg ctcacgggtt tttgactgac
    17761 tatcccaacc aactactatc agttctggat tggtctgacg aatacaaagt gccatagaag
    17821 caccaatcag tccaagcccc acgataaaaa catgttgtgc catcttattt gccccctttt
    17881 tagtaatgtt tcaagtagtc acggtactcc ttcactgcag ctttcaactc aacaagcgaa
    17941 tcacttggga attttgacaa tagctctgtc gctaccacag tggctacaac attttccgca
    18001 acgacgctag ctgcaggaac tgctgtacta tccgaacgtt ctacacttgc tttgtaaggt
    18061 tcttttgtat cgatatcaac actttgaagt ggcttgtaca atgtaggaat gggtttcatg
    18121 accccgcgaa tgacaagtgg ttcgccattg gtcattccgc cttcgaagcc gcctagatta
    18181 ttggtacgtc ggaaatagcc tctttcttct tcccatagga tctcatccat cacttctgag
    18241 cctggtaatg aaccagaagt gaatccgacc ccaaattcta cgcctttaaa ggcattgata
    18301 ctaaccacag cttgtgcgat tttggcatct agcttcgtgt cccattgtac gtagcttcct
    18361 aatccagctg gaacgcctcc aacgagcact tctacaattc ctccgatcgt atctccattt
    18421 ttctttgtct gatcgatcaa atcttttatt ctttgctcaa ctgctggatc aacaactcgt
    18481 acttctgacg cttcagaaat ttctttgatt tcttgaatcg agatatttcc aggtatttct
    18541 gcttggattc caccaagaca aatcacgtgt cctgctacga tgatgtcaag ttcttccaga
    18601 attttcttgg caattgcgcc gattgctaca cgcatggtcg tctctcttgc agaggaccgt
    18661 tcaagcacat tccgaagatc tcgatgatgg tatttcatac cgcctaccaa atccgcgtgt
    18721 cctggacgcg gacgtgcaac tcgccgcagt gattggtctt tttcaggcac ttctgctaca
    18781 gacatgacag ttgtccaatt tttccaatct ttattttcta ccactaaagt gacaggtgaa
    18841 ccaattgttt tgccgtgacg gatgccagac gtgatccgaa cacgatcttt ttcgatcttc
    18901 atccttcctc ctctgccgta accagcttgt ctgcgagcga gttcgtgatt gatttcttct
    18961 tctgacagag gtaatcctgc tggtagtcct tcaataatgg ctgttaattc tggtccatgg
    19021 gattctcccg cagtcatata acgcatctta cagtcctcct aagtaatctt tgaatgtctc
    19081 tgtgggaaca ggaacgattt ttgcttgccc aatcttttct agcaagatga tattcaattg
    19141 gcttcctctt gctttcttat catgggttat cgcgtggaat aattcatctg gatgacttag
    19201 atcgtacgta atcggcagat ggaatttttg aagtatcctt tctaaagcag ctgtcgatcc
    19261 agttggagac aagccgattt tttctgcatg agaagtgatg gctaccattc caatagctac
    19321 tccttctcca tgactgacta ccccatatcc tgctgtattt tcaattgcat ggccaattgt
    19381 atgaccaaaa tttaaaataa gtcgatttcc ttggtcaaag acatcttctt ccactacttt
    19441 tcgtttgatt tccaacgtag cagtaatgat tggaacagca tgttccagaa gatctttttc
    19501 gtctttcagc tcgttcagct gtttccaaag cgttgcatct gctatagctg ctgatttgat
    19561 gatttcagcg attccttctc gtaaacgacg taccggcaaa gtttttagaa cctcaggatc
    19621 aatcaataca ccagctggct ggctaaatgt tccgacaagg tttttcgctt tgtttgtatt
    19681 gactgctgtc ttcccgccaa tactagaatc tacttgtgca agtagcgtag tcggaatttg
    19741 aacgaaatgg atcccacgca tgaacgtcga ggccacgaat gctgctagat cacccaccat
    19801 tcctccacca agtgcaagta tcccatcgct gcgggtaaaa tcattatctg ctaaaaaatc
    19861 gtataactca gctgcttgtt ctaaagattt actggtctca cccgccggta cgattgaaag
    19921 gactggttca aaattagctt gtctcaattg gaacatgatt ttttctgcat atagtggagc
    19981 aacgtttgta tcagtgatca cagctacttt ttgaggtctc caaatcgttt gaagccatga
    20041 tccagcctgt tctagtgcgc ctttttcaat atgaatatcg tatttttggt tatcaacatg
    20101 tacagtaagc attcgtttca cttctttctt ttaaaaagct ggaattaatc gagtgtctga
    20161 atcttttcca ttgcttcttt catgatcgca acttctttca tcatgcgtga gtaagtcttt
    20221 tcattcaacg attggggacc gtctgaccaa gcatttgcag gatcaggatg gatctctacg
    20281 atcatgccat ctgctccgct tgccacaccc gcacgagcca ttggtggtac aagttcccaa
    20341 attcctgtac catgacttgg atcaacaatc acagggaaat gagttaattt tttcatcaat
    20401 gggacagcac ttaaatcaaa cgtattacgt gtcgctgttt cgtaagtccg aatcccacgt
    20461 tcgataaaaa tgacaggaga tttgtcttcg actgcaatgt attctgcagc attaagccat
    20521 tcattgatcg taccggaaat tccacgtttc aatccaacag gtttacctgt tttaccgaca
    20581 gcagatagca gtttaaaatt ttgcatatta cgtgcgccaa tctgtaggat atcgctgtac
    20641 tcagccacca tatcgatatg cccttcatcc atcacttcag taatcacttt cattccaaat
    20701 tcatcagccg cttgacggat gtatttcaat ccttcttctt ctaaaccttg gaaagcatat
    20761 ggagaagtac gtggtttgaa ggcaccacct cgcagaattt ttgcgccccc ggctttggcc
    20821 attcgcgcac attctctgat ttggtctaat ccttcgatag aacaaggacc agccatcgtc
    20881 acgaaactgc cgtcaccaat ttttactccg tctacatcca cgactgtatt gccaggatgg
    20941 aattctcgag aagtcaattt gtatgtgttt aaaatacgca cagcattttc tactccttca
    21001 tagcgtgtaa atgctccttc ttgtaaactt cgcgtatcac cttttagtcc aatcactact
    21061 cgttctgttc cttgatcgat tgagactttg aatccttctt tttcgatatg atcgacgact
    21121 ttttttattt gttcttccgt tgcttctttt ttcataatta ctatcattgt ttttcccgct
    21181 ttcttttgtt tacttatcta tcttggctga ttttctctac tttttcaagg tggttttaca
    21241 ttaattccta ctaaatgacc gtgtcctgtt gttctcattt tcgctccttc tttcctactt
    21301 atgacccaga taatcaacaa aaaaagatgt ccctgtagga aattgcctct acagtgaaca
    21361 tcttcaacga gccttaaaaa gcgctgcaaa aatataaaat agccactata gatgaatttc
    21421 tctacgtggc tgtaagtcgt gtttaaaaat ctttagccat catagataca aacctggttt
    21481 gtttgtaccc acgaagtcat gaatacaaac ctatctaaaa tagctaaagt aatacgtatt
    21541 cagttttgta agttttctag atttcataaa aaatcgctcc aaactgatgt aagaattgta
    21601 cctagtatag acataaaaaa atcgactgtc aatcattttt atgaaacttt ttttaatttt
    21661 ctgatagtta actttgtttt tcagaaaaat aacaattggt tttattgaag aaaatagtca
    21721 tgaacaaaag tatctgagaa cttttttact ctcttgttca tgacatatag aataaagcag
    21781 ctttgtcttg taaactccgt ttttcaaata ataatctaaa gattgctact gaataataaa
    21841 gccgatttca tggtcctctt cgctgctgat tcggtaaggt gactcaacat ccgctcccca
    21901 gctattgata cccccgactc ctcttacttt tgcaaaaatc gtaagaaccg ttcgtctttc
    21961 tggcggtagt tcttctatat gtgttgcctg ttccagttct tctgctttga atggtaaagc
    22021 ggaaaaagca aatggcgtat cctgctgttc aaatcgcaac gaaaaatctt cttgatcttt
    22081 atccgtatta tccaacgttt gatttcttgt tagttctacc catttcgttt ccatatgcat
    22141 gccgcattct tggggaacaa ggtatgggga aacggggagt cctgccactt tataaatacc
    22201 ttcgacacca ccagccatcc gatccggata tgtttcccct gataggcctt catactcaaa
    22261 aaattttgct ttcgttggca taatgaacct taaacccaat gcgggtaatt ccggtaatcc
    22321 tttttgtcca taataatgca tattgacaag cattttaccc tctccagcga tttggtagga
    22381 aattgtcact tgggtttttg gtactgtgtt gatttccagt gtaaaaatga tttcaaccgt
    22441 ttcagcgtat tcattacttg aatattgatt atttactgga gcaatcggca aatcgatctt
    22501 tttattgtcc accagtactt ctatttcttt gacttttgga tacaatccgg ctcctaacca
    22561 cataccggat ttaaatccaa atccgctacc tctgtcatta tcggtcgttg ctcgccaaaa
    22621 aactggaagt gtttcccggt atagccattc ttttccgttt ttattgagcg attccagtcc
    22681 gcctcttgta taagaaaaaa tataatgcgt attccccgat ttgacaccta atgtacagtc
    22741 gccgaagacg attgcaactt tttccgtatc catatgactt ttatttactg tatttttcat
    22801 aataatatct tacctcctgc atggcgggtt tttcttgtcc atctgcaaaa acgatcccat
    22861 tccctgagaa ttcatagtca cttggtttat cgtcaaagtc accgccatag cgcatcactt
    22921 ctctgcctgt gattggatca gtcacttgga tcgcctgatc tttaaaatcc catatatagc
    22981 ctccttggta catttcataa cgatcaagca acgtcatgta agaatccatt ccacctaacg
    23041 aattccccat gtcatgcata tattcacata agatgaacgg tttttccgct ttattttcaa
    23101 ggtagtcaat gatctcttct ggtggcgcat acatgcagct ttttacatct gaaatcgaat
    23161 cttcgaatgc tggatttgga aaattccctt cataatggac aagtcgatcg gggtctactt
    23221 ttttgaagta atcgttcatt tgtcgaatgt tttcttccgc ataagattca tttccaagag
    23281 accaaaaaag aatacttgga tggtttttta atgtttcgaa attcgttttt gctcgatcaa
    23341 gaacagccgc ctgccactga ggtactgcac ctggtacgtt gtaagaaggc tcaaatgcgc
    23401 ccattttttg ccatgagcca tgggattcga ggttcgtttc cgccatcaca tggattcctg
    23461 cttggtcgca taaataatac caagtgatct ggttggggta atgagatgtc cgtacgccgt
    23521 tgatctttgc attttttatg atagccaaat ctttttccat atcttctata gtgatggcgc
    23581 gtcctttttt cggatgccac tcatgtcgat ttaccccgtt gataatcatc cgttttccat
    23641 tgaagtagat gattttatct ttgatttcga ttttacgaaa accgaaggaa tagtcaatat
    23701 actccgttac tcttttttct tcgtctatcg tctccaattc aagcttatat aaattgggct
    23761 gaaaatgccc ccacagtgcc acattttcaa atccatcgat gcgaatcgtc atttgctctt
    23821 ttaacggata ttgctgttga tagatttcct tcccatcagg atctagtatc gctacattca
    23881 gctgactgtt tttggctact tgctcaaaag acaaatctac ttcaagtttg ccattttgac
    23941 atttgtcatc taagcgaggt ttgatccaaa gatcttctaa atggttttgt cctcgagcaa
    24001 ctaagaagac atctctgaag atcccaaaaa atcggaaaaa gtcctgatct tccaagaatg
    24061 cagctgtact tcttttgtaa acctccacag ctagaatatt ttcttcttcc aaataaggtg
    24121 ttaaatcaaa ttcagacgga gtgaacgaat cttcggcata cccgataaaa tgaccattca
    24181 accaaataaa cattgcttgt tctacaccag caaaatgaat cgagatttgt tttcccttta
    24241 gaccttcttc taatcgaaaa gtcgtcaaat acgaaccaac cggattgtct ttagcagctg
    24301 aaaagatccc ttccgcctct ttctcagggc ttgtcgtgaa agggggacgg cgaaatacat
    24361 gtccctccca cggatacatc gtattgatgt aatggatctt gtcataattt gctaattcaa
    24421 tatgactagg aacagtgatt tcatcaaaag aacaggcatc aaaatctttt ttataaaatg
    24481 tttttggtcg taccgaagga tttggcgaat aacaaaaacg ccatgatcca tttaaagact
    24541 gtttaaggga ggatgtggtt tctacttctt cccttgttgc ataacaaaca tgatcgctat
    24601 gtgcatttga ttggttcact ctaaaaactt gtggatcatc taaccatttt atatttgctt
    24661 tcatactttt ttccttctct ctcataactt tttgaaatga agcagttctg tttggaaatc
    24721 accttgaaaa tcggggaagt aaagtccaac tgtcatcaat tcggcccccg aaaatatccg
    24781 cttcgaggtc tgttcctgat aaagtgcctc atcatctaac cccatcagat atacttcatg
    24841 gaacgctggt tgagctgaag ctagtatcct ccctaaaaac acaatagctt catcttgttt
    24901 aggagacaca aacatccatg cggcaatatt ttcttcaaaa ggactcgcca aacgataata
    24961 atggccatac tggatcaccg gacgaatcgt ttgataggat ataatttggt cttttacttg
    25021 ctttttttct tcaggagaca gctttgtcaa atccagttca taaccaaaaa cagcgctcat
    25081 agctgtttct cctcttgttt tcaacgaagt agatctgtcg gtctgatgat ttggtacagc
    25141 tgatacatga gctgtgatgg acgaaatcgg ataagcaagg cttgttccat attggatttt
    25201 catacgctcc actgcatccg tgttatcact tgtccatgac tgcggcatat aataaataaa
    25261 cccggcatca aaccgtccac ctccaccaga acagccttcc cataagattt ccggataatc
    25321 agttgtcaaa tgttcaagta gttcataaag cccgagcata taacgatgcg ctacttctcc
    25381 ttgtctctgt gggtcaaggg taatcgaata gacatctgaa agcgaacggt tcatatccca
    25441 tttgatgtag tcaagaggaa tcgtatctaa aatctttctc atttgtttct caatcgtctg
    25501 ccgaacatct aaccttgtaa aatccagtac atgttgtgat ctggaagcag aaggcattct
    25561 acctggctcc tgcataagaa aatcaggatg tgttcgatac agttcagaat caaccgagat
    25621 catttcaggt tcaaaccata aaccaaattt caatcctttg ctatgagcat aatctgctat
    25681 ttcacgtaat ccatttgtca acttgccttc atactcgaac cagtctccta atgaagaatt
    25741 gtccgcatct ctttttccaa accagccatc atctaatacg aacatttcga tgcctagctc
    25801 ctttgcttca tcaatgatcg ccttgatttt ttcactattg aagtcaaagt aagtggcttc
    25861 ccagttattg accagaatcg gccgttcagc aaattgatga cgacctcttg cgattctttc
    25921 acgtagcaac tcatggtgga tctgactcat tttgttcaat ccctgacttg agtaagaaag
    25981 gatcatttca ggtgtttgaa aagactggcc tgcattcaat tcccacgaaa aacgatggct
    26041 gttgatccca ccgacgactc tcaattgatt gatctgatct ttttcaagtt cgaaagaatg
    26101 gttgccggaa taaacaaatt gaagtccgat cgcttctcca gtattttctg tcgtatgatg
    26161 atgaactaaa gcaataaagt tattcatatg gtgactgctc gttcctcgac ggctttcaaa
    26221 tacttttgtt ccagataaaa cagattgccg tgaaatctgt ctttcattga catgtgctcc
    26281 tggcaaagca atgacttcat caaatcgcct agtatgggca aagtctagct ggaaactagc
    26341 cgctttttct agtttgattg tttctccggt ttcatttctt atctttacag atcgtgtgat
    26401 cactgctcta tcagtaaata tggtatagaa caaatcgaaa taaatcgctg tttctctatc
    26461 cttaagtgaa atcaccaacg tttgtgcctc tgacttgtcc atcacataag tttgaggcaa
    26521 gccttcgatc tctggcttcc catctgtaat ataatggctg tcatatctca gatccagtaa
    26581 gtctgatcca ttcttgcgct gaatgatcga tgcgggcgtt cgaaagtcca tgctgccatg
    26641 agaagagtat tcttgcggta gtgtatcttt cgacagagac cggtcaggat ttaagggaac
    26701 atttcctgaa aatccacgat ctcttcgggg ataattttta ttgtctttgt actgcttgac
    26761 tggtttgcca aaataaatat gcgccaatac attgctttct tctatcttta tcagataaga
    26821 aagaaatgta tttcgtaaat ggaagactcg gctcttttca tcaaataaga tgaaattttt
    26881 atctgttttt ctatgcgtaa tatccatcat ttcactccca acaaaacgga aaccgtttac
    26941 ttttttttat aattcctgta tactgtttac taaacaattt tgtcaataaa aattttttat
    27001 ttttttgagg agtgtgtaaa aatggttgga attagagatg tcgcacgaaa ggcaaatgtc
    27061 tctcctgcta cagtttcccg tgtgttgaat aacgatcaga cgatccatgt ggctcagact
    27121 actcggcaac ggatagtaga ggcagctgct gcgttggatt atgacatcag tactcgtaaa
    27181 tatatcaaaa agagaatgcc ttcgattggt gtgatctcta cgatcggcaa agcgagcgaa
    27241 gaacaggata tctattacaa acatttgcga gtagggatgg aagaagaagc tcgacgtctg
    27301 catttaggga tgaatcgaat ctataatcta tctgataatc ctaaacaatg ggaagatcta
    27361 gatcagttag gtgcggtgat cgttgttggg actgttacga aagaatcgat taccgccttg
    27421 ttaaaacaaa acatgcaaat agtcgtcgtg gataaccctg acatccagca agaggtcgat
    27481 atggtgtatg cagatcttga acggatgact aaaaccgtac tggaattgtt cttagaaaat
    27541 ggtcataaaa gaatagccta tatcggggga tataaagtcg atatggatga attcggtggg
    27601 aagcagattt ctataaatga aaagaggatg cgtgcctatc agcattttat gatcgatcat
    27661 cacttagaaa aatatatgtc ttatcatcta ggtggctgga cagaaaaaca aggtgaggta
    27721 cttgcgacta atctattaga aaatgaatcc cctcttccta ctgccattct tgtcgggagc
    27781 gatccaatgg caattggtgt ctatcgggca ttgaaacaaa aaaatatcca aattggagaa
    27841 gagattgttg tagcaagctt tgataatatc gagacaatcg caaacctctc ccctggcttg
    27901 accagtgttc aaatcaatgc gaaatcaatt gggcaagcag ctgttcgaat ggcattggag
    27961 cgaattgacg gtatacggga cgaaccaatc attttgactt atcctgcacg attgattgtt
    28021 agggaaagtt ttatcccaag aacaaaaagg tattgaaaga gaggttgtga aaagccgctt
    28081 cgtttcttca tactcaaaac gaaacggctt tttcacaacc tcttacttat acttattcac
    28141 aaaatccaat gtctgctggt aacaattttg cgattctttt agcgtgtaat caaattggta
    28201 ttcatgggta atctcttttt ttgtatctgt ataaaacaag gattgcacgg gtacctttaa
    28261 ttctgtcaac cgattttcta atgcttgacc ttgctcctgg aatgagtatg catttccgtc
    28321 agttatatac gttggcggaa attccttaga aacatggtca gccacactag cttctttcaa
    28381 ttgctcactc gttttccaat cttttgttcc aatcaacgac cacgcaacgg ttttgacgaa
    28441 aaacttcata aatcgatcat ccgaatgctg ctgtgctgtt agcttcaaat caacaggtcc
    28501 gcaataagaa atggttcctt tcagactatc ttttggaagt agctgtttga ttttcatttg
    28561 tttagcatac gcatcattcg tttgtatagc tgcatattgc aatgcgattt gtgaacctgc
    28621 actatctcca ccaaaaaata attgttccat gtctagcaat ttgtcgtctt tttcttcagc
    28681 taataaatct ttgatcagtt cattcacttg aagaacttga ttagggtatt ctgaatcagg
    28741 cgctaattca taattcatcg caaccactgc gatgttggcg tctgaaacta attttgtcgc
    28801 aaattctttg acacccgatt tatctccgcc gacgaatcct ccaccatgta cccaaaatag
    28861 aacaggaaca ggccccttgc tgttttttgg atagtagatg tcataagtat tctctttata
    28921 cttggactca tacgtcaaat ctgttttttt cgccacgttt ttttctgctt gatcgaacgt
    28981 ttttttatca gtgatttgaa cagtatttga aaacatatgg ttgatcaaga atgctccagg
    29041 tctgggggaa agctggaagg caagaaagat tgcaaacgcg atcccaagaa tgattccgaa
    29101 gaaccatccg ataaatttaa gaattttctt tttcataagg ctccctcagt agttagtatt
    29161 aagcattctg attataccat agtgttattt cctatcaagc tctcctagat gatttaatga
    29221 ttttccccaa acttcttctg caatgctttt gacaaaagaa attttttcca ttgttcttca
    29281 aacaaaacat tttcttcttc tgttgaagca aatccacatt gaggacttaa gcacaaacga
    29341 tccaaaggca gatatcgtgt cgcttcgtag atccggtcaa tcacttgctg gtgctcttcc
    29401 atttcgccat ttttcgttac agtcaaaatc taagacaact aatttatctt cagagacttt
    29461 ctctaaaaga acaaaactcc cagcacgttc actatcgtat tctaaataat aggcacggac
    29521 attttcttga gtaaaataat gggtctgcta cgtcgtcatc ccccctgatg ccgccaaaat
    29581 cgaataataa tttccgcgtc aaacatgtat atttagtgtt gaatcatttg agaatatgaa
    29641 aataaaaatc tttttgatca atcagttaat caaattgaaa taacgaaaaa tctgagacag
    29701 aatgacgttc attctgaccc agatttgatt ttgcacaact caacagtcct tattggcaaa
    29761 tcgccaaaat aatgtagact aa
//
LOCUS       DACDLM010000031        29022 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.031, whole genome shotgun sequence.
ACCESSION   DACDLM010000031 DACDLM010000000
VERSION     DACDLM010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29022
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.031"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..1030)
                     /locus_tag="IV356_001443"
     CDS             complement(<1..1030)
                     /locus_tag="IV356_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP9015135.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1112..1801)
                     /locus_tag="IV356_001444"
     CDS             complement(1112..1801)
                     /locus_tag="IV356_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAP9015136.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="IV356_001445"
     CDS             complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="IV356_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HAP9015137.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2328..2831)
                     /locus_tag="IV356_001446"
     CDS             complement(2328..2831)
                     /locus_tag="IV356_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HAP9015138.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     gene            complement(3157..3846)
                     /gene="rplA"
                     /locus_tag="IV356_001447"
     CDS             complement(3157..3846)
                     /gene="rplA"
                     /locus_tag="IV356_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HAP9015139.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(3950..4372)
                     /gene="rplK"
                     /locus_tag="IV356_001448"
     CDS             complement(3950..4372)
                     /gene="rplK"
                     /locus_tag="IV356_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HAP9015140.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4715..5383
                     /gene="sdaAB"
                     /locus_tag="IV356_001449"
     CDS             4715..5383
                     /gene="sdaAB"
                     /locus_tag="IV356_001449"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit beta"
                     /protein_id="HAP9015141.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5396..6268
                     /gene="sdaAA"
                     /locus_tag="IV356_001450"
     CDS             5396..6268
                     /gene="sdaAA"
                     /locus_tag="IV356_001450"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HAP9015142.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6359..7378)
                     /locus_tag="IV356_001451"
     CDS             complement(6359..7378)
                     /locus_tag="IV356_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAP9015143.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7551..8438)
                     /locus_tag="IV356_001452"
     CDS             complement(7551..8438)
                     /locus_tag="IV356_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAP9015144.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(8515..9060)
                     /gene="nusG"
                     /locus_tag="IV356_001453"
     CDS             complement(8515..9060)
                     /gene="nusG"
                     /locus_tag="IV356_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HAP9015145.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9161..9331)
                     /gene="secE"
                     /locus_tag="IV356_001454"
     CDS             complement(9161..9331)
                     /gene="secE"
                     /locus_tag="IV356_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HAP9015146.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9355..9507)
                     /gene="rpmG"
                     /locus_tag="IV356_001455"
     CDS             complement(9355..9507)
                     /gene="rpmG"
                     /locus_tag="IV356_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAP9015147.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9669..10313
                     /locus_tag="IV356_001456"
     CDS             9669..10313
                     /locus_tag="IV356_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAP9015148.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10369..10872)
                     /locus_tag="IV356_001457"
     CDS             complement(10369..10872)
                     /locus_tag="IV356_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAP9015149.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10885..10931)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11469..12434
                     /locus_tag="IV356_001458"
     CDS             11469..12434
                     /locus_tag="IV356_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAP9015150.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12533..13705)
                     /locus_tag="IV356_001459"
     CDS             complement(12533..13705)
                     /locus_tag="IV356_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9015151.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13692..14837)
                     /locus_tag="IV356_001460"
     CDS             complement(13692..14837)
                     /locus_tag="IV356_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9015152.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14851..15783)
                     /locus_tag="IV356_001461"
     CDS             complement(14851..15783)
                     /locus_tag="IV356_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9015153.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15900..16979
                     /locus_tag="IV356_001462"
     CDS             15900..16979
                     /locus_tag="IV356_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAP9015154.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            16976..17605
                     /locus_tag="IV356_001463"
     CDS             16976..17605
                     /locus_tag="IV356_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP9015155.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(17715..17942)
                     /locus_tag="IV356_001464"
     CDS             complement(17715..17942)
                     /locus_tag="IV356_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP9015156.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18045..20633)
                     /locus_tag="IV356_001465"
     CDS             complement(18045..20633)
                     /locus_tag="IV356_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HAP9015157.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20653..21312)
                     /locus_tag="IV356_001466"
     CDS             complement(20653..21312)
                     /locus_tag="IV356_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAP9015158.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21361..21864)
                     /gene="trmL"
                     /locus_tag="IV356_001467"
     CDS             complement(21361..21864)
                     /gene="trmL"
                     /locus_tag="IV356_001467"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HAP9015159.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22085..22951)
                     /locus_tag="IV356_001468"
     CDS             complement(22085..22951)
                     /locus_tag="IV356_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAP9015160.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23060..23701
                     /locus_tag="IV356_001469"
     CDS             23060..23701
                     /locus_tag="IV356_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HAP9015161.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23763..25124)
                     /gene="mgtE"
                     /locus_tag="IV356_001470"
     CDS             complement(23763..25124)
                     /gene="mgtE"
                     /locus_tag="IV356_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HAP9015162.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25142..26041)
                     /locus_tag="IV356_001471"
     CDS             complement(25142..26041)
                     /locus_tag="IV356_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAP9015163.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26043..26840)
                     /locus_tag="IV356_001472"
     CDS             complement(26043..26840)
                     /locus_tag="IV356_001472"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HAP9015164.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26818..27522)
                     /locus_tag="IV356_001473"
     CDS             complement(26818..27522)
                     /locus_tag="IV356_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HAP9015165.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27653..28228
                     /locus_tag="IV356_001474"
     CDS             27653..28228
                     /locus_tag="IV356_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HAP9015166.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28346..>29022
                     /locus_tag="IV356_001475"
     CDS             28346..>29022
                     /locus_tag="IV356_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAP9015167.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8543 a         6146 c         5221 g         9112 t
ORIGIN      
        1 atacagtatt atttcggttg cttgctgctt cacctagccc ttgtactcgt gtttgattgg
       61 cgacttgacc aaattgattc ccgacgtcta ataaaataat agctaaaagc aaaatggcca
      121 aatggcttcc gccaaccaat aaagcaataa agcttattgt ttgcataaca agtcccatat
      181 acacgatttt tctttcagaa taagaatctg ccagtcgtcc cacgataggt gcagcaactg
      241 ctccagacaa accaaaaatc gctaatatcc ctgcttcgaa tgttccccaa ttgtaggcgg
      301 gactgctgat ataaaaaatc aacgtagacc aaaagatcga aaatgttcca aacatgaaaa
      361 atccactgac tgccgcttct cttaatagac gttgagaagc aactaaatgc ggcaaacttt
      421 taagtgaatc aaggtatgaa acagctgtac tactttgctg gacagaacgc ggcattttcc
      481 agtaaagcag aagtgtaaga attccgactg cacataaagc aaataaatag atcatccgcc
      541 aagaaaaaag actggcaaca ataccagata ccgtccgaga aagcaaaatc cccacgagta
      601 aaccgctaag caatgtaccc atgaccttcc ctcttgcttt tggtcccgct agtaccgcac
      661 cgtaaggaat gatgatttgc ggcacgatcg aaagtaatcc tattaaaaaa gaagcgcatg
      721 caaataacgt aaacgaaggc gcaaaaaaag cggccaacag agagacggca gataacgcta
      781 ccattcgaat gatcaatttt ggacgatcca ccacgtcccc taaaggaact aaaaacagta
      841 accctaacgc atagcctaat tgggtcaaca tcgtcaatat cccgactgca cttgtgctaa
      901 cagataaact agctgctact tttgttccaa tcggctggat gtaatacata ttggcaacaa
      961 caacgccaca agtgattgat aatagtaaaa taagcgaagt tgttaaaggt gttttttcat
     1021 tactcttcat tgatttcccc catttcctat cttagtttac aacttatgga aaagattgga
     1081 aatagaaaaa tacaactatt cgccacactt attatttgtg cttttgtttt ccttgttttt
     1141 tcttgcgatc tttataaatg aagacaacta accctactag cacagtaaca cttgcaacca
     1201 acgtgactgc agttttgtta tatccgtgaa acagagcttc tccaccacac gcatacaaca
     1261 cagacgaagg gatgactcca atcacgatcg acaatatgat ttgctgtaga ggcaatttca
     1321 tcgcatctgc agcaaaattg accatagaag atggaataac cggtatcata tagcctaaca
     1381 ttacacctat ttttggatgt ttcatttgtc ggattgcttg cacccaatga ttcgtttcgg
     1441 ttttcttatc taaaaatttt aagcgatgca taaggaaaat tgcagtgatg ttaccaagag
     1501 cattacccaa aatgttgatg atcgcacctg tcagtggtcc aaagctcaaa ccagcaatga
     1561 ctccaactac tgaagtagga atacctggaa cagcacacat caccgctgtc aatacgatca
     1621 agagtatcga tgcaaaagtc ccatgcgaac gaatatgtgc gagtagctct gccttactcg
     1681 ctctcggatt taaaaataat tggatgtctg tctgatattc taaatacaac cgatagccca
     1741 ctaccagtat cagaatgatt cccaacgaga tcaacatcaa tcggattatt ttctttttca
     1801 tatttcctcc tgaaaaaaat ctatattcat taaataatag tttaacataa aaacaaaaaa
     1861 gcaccgaaat ccaacatagg atctcagtgc ttttaaatag taaaaattat ttaacagtta
     1921 cagatgcgcc aacttcttca agtttagctt tcaattcttc agcttcttct ttagatacgc
     1981 cttctttaac tggtgcagga gcgccatcaa ctacagcttt agcttctttc aagcctaaac
     2041 cagttgcttc acgaactgct ttgataactt taactttttg gtctccagct gcagttaatt
     2101 ctacagtgaa ttctgtttgt tcttcagcag cagcagcgcc accagcagca gctacagcta
     2161 caggagcagc agcagatacg ccaaattctt cttcaatagc tttaactagg tcgttaagtt
     2221 ctaggatagt tgcttctttt aactcagcaa cgatgttttc aatgttcaat gccattataa
     2281 tttcctccgt ttaattgttc ttttttattt aatgctttat gcggcaatta agctgcatct
     2341 ccatcttctt tgtctgccac tgctttgaca gcgtaagcca cgttgcggac tggcgcttgt
     2401 agtacagata gcaacataga tagaagtcct tcgcgatttg gcaattttgc caatgctgtg
     2461 atttcttcca atgaagagac tttaccttcg atgataccgc ctttgatttc taatgctttt
     2521 gcttctttag caaattcgtc catgattttc gctggtgcga ctacatcttc gttactgaat
     2581 gcaacagctg taggtccagt gaatacttcg tccatgcctt caaggccagc ttttttagct
     2641 gcacgtgaaa gaatagaatt tttgataact ttcatttcta cgttagcatc acgaagttgt
     2701 ttacgtaaac gtgttacttc atcaactgtt aatccgcggt agtcaacgac tactactgat
     2761 gcagctgctg taaatttttc gcttacttca tcaacgattg ctgctttttt tgcgataatt
     2821 gcttcactca tttttgagtt tcacctcctg aattttgatg gaagagtttt ttgcactgaa
     2881 aaggcaagtc acttttatag ttactttgct caaccagtat tgttcatcat ctcttcactt
     2941 cgttcatagt gattcacaat aaaaaactct atgccaccgc agacatagag ggactattga
     3001 atatattcaa taaacgtcct cggtaggaaa ttaaggcttg atgccaccta ctgtcttcgg
     3061 tacaagttaa ttattaacct caactagctt agcatgctaa actagttgag tcaagaatta
     3121 tttttcagtt ggatcaatca acattctaat atttaattag aaagaagctt ggtcaacatg
     3181 gataccaggt ccaaatgttg ttgtgatcgt tacatttttc atgtattgac ctttagctgc
     3241 tgatggttta gcttttagca atacatcatg gattgctgca aagttttcaa ctaatttttc
     3301 atcgtcaaat gaaacttttc cgattggtac atggatattt ccagctttgt ccacacggta
     3361 agttacttta ccagctttca cttcgtttac tgcttttgtt acgtccattg taactgtacc
     3421 agttttaggg tttggcatta agccttttgg tcctaatact cgtcctagac gacctacagt
     3481 agccatcata tcaggtgttg caacaactac atcaaagtca aaccatccgt tttggatttt
     3541 ttgaaccatg tcgtcgtcac ctacgaaatc tgcaccagct gcttcagctt cttttgcttt
     3601 gtctccttta gcaaaaacta aaacagtttg tgttttacca gttccgtttg gtaatacaac
     3661 agcaccacgg atttgttggt ctgctttttt agggtctacg ttcaaacggt atgcaacttc
     3721 aactgttgca tcaaattttg caatgtttgt ttcttttgct aaagctactg cttcggcaac
     3781 aggataaact ttacttgaat caactttttt taatgcatct tgcatttttt tgctcttttt
     3841 agccattttg gttcctcctt gattgtggtt ataacggttg tacctcccac gtgttctata
     3901 tctttcaata tagagccaac tgagaagctg ctgtcttagg gtgtatagat tattctacag
     3961 tgatccccat gcttcgtgca gttccttcaa ccatgcgcat tgctgcttca acgttagctg
     4021 cgtttaggtc ttccattttt aattcagcga tttctcttac ttgatcgcta gaaactttcg
     4081 caactttatt tttgtttggt tcgcctgaac ctttttcgat tttagctgct tttttcaata
     4141 gaacagcagc tggcggtgtt tttgtaacga atgtgaatga acggtcttcg tatacagaaa
     4201 taacaaccgg aatgatcaaa cctgcttgat cagctgtacg agcgttgaat tcttttgtga
     4261 atcccatgat attgataccc gcttgaccta gtgcaggacc tactggtgga gctggagttg
     4321 ctttacctgc aggaatttgc aatttaacga ttttttctac tttctttgcc acgagacata
     4381 cctccttaag tccgtgatgt ggttaattgg agatgcatat ttctcctccc acgttttatc
     4441 tgatctgaaa aaatccagac aaataatgtg caaaacaatg cacactggta cagtatagca
     4501 aatttatttg ttttttcaag atttttttct gctattttta cattttgctt gaataaacgc
     4561 taaatttatt ctaaaaaaac aacaattttt cgttctcatt tcttctttta tgttacactt
     4621 gcgctagcat ggttcaacag atgaaagcaa acaataacac ggttttttag acccttgtac
     4681 aaagattcct acataacaaa atgaggtgga gaaaatgaaa gatttaaggt atagaagtgt
     4741 ctttgatatt attggacctg tgatgattgg tccaagtagc tctcacactg ccggagctgc
     4801 tagaatcggg aaaatcatac gtagtatatt tggcgaacag cctgattctg tagatattta
     4861 tctatatgaa tcatttgcaa aaacctatcg ggggcacgga acagatattg cattagttgg
     4921 cggcctgtta gggatggaac ccgatgatga acgtttagct gattctttga aattggcata
     4981 tgaagccggt atggaagtct tgtttgttcc taagagtgaa aaagccgaac atccaaactc
     5041 tgtaaagatg cttctaaaaa aaggaacacg aaagctttca gtcactggca tttcgatcgg
     5101 cggtggcaat atccagattt ctgaattgaa tggattcaaa atttctttaa gcatgggtac
     5161 tcctaccttg atcgttgtcc accaagatgt tccaggtatg attgctaaag tgactagtat
     5221 actttctgag accaatacga atatcggcac tatgacagtg acacgggaat caaaaggtga
     5281 aaatgccatt atgataattg aagtagatga tcctcaagta gaagaaacgg taaaaagact
     5341 caaacagctg ccaaatatcg acagcgtaaa ttatttcgat taaggagcta aaaaaatgtt
     5401 tttatcgatt gaagaattag tagatcaagc aaaagcttat ccaagtgtag cagaattgat
     5461 gattgcagtt gaaatggaaa tgagtggccg ttcccgtagt cacatcatcg agatcatgga
     5521 aaaaaacctc tcagtaatgg aacaatcaat caacgaggga aaagaaggtg ttacctccgt
     5581 cacaggaatt accggtggtg atgcaaaaaa attagatgat tatttaaatg aggcagactt
     5641 tttaagtgga gaaacaatct taaaagctgt acgcaatgct gtagctgtta atgaagtcaa
     5701 tgcaaaaatg gggttgattt gtgctacacc gactgccgga agcgcgggtg ttgttcctgg
     5761 tgtgctgatg gctgtccgag atcggcttga tttgacacat gaacagcaat tggaattctt
     5821 atttaccgct ggcgctttcg ggttagtcat cgcaaacaac gcttctatca gtggtgcaga
     5881 agggggatgt caagcagaag ttggttctgc aagtgcaatg gcagcagcag ctttggtttg
     5941 tgcaaaaaat gggactcctc atcaagcagc acaagcagta gccattacat tgaaaaatat
     6001 gatgggactg atttgcgatc ccgttgcagg cttagttgaa gtcccgtgtg tcaaacgtaa
     6061 tgctttaggc tcttctcaag cttttatctc tgctgatatg gcattagcgg gtatcgaaag
     6121 tgtcattccg ccggatgaag tcgttgctgc aatgtaccaa gtcggacgtc aaatgccgtc
     6181 gattttcaaa gaaacagcag aaggtggctt agctgttacg ccaactgcta aacgacttgc
     6241 ggaagagatt ttaaataaga gggcgtgata aagctcctta atttcgagta ttaagagatt
     6301 agttatcttc ataacaaaaa acgaagagag gactaattgc ccttctcttc gttttttatt
     6361 aatccatcaa tttcgtattt tttacttcat cgatcgtttt tgttcctgca agttgcatcg
     6421 tgatcgacaa ttctttgttc aggtgttcaa aaacagatgt tactccttct gccccaccta
     6481 gattcaaccc ataaatcact ggtcggccaa tcgcaactaa gtcagcacca cttgccagag
     6541 ctttgaagac atgctctcct cgacggacac cagagtcgaa aatcactggt acacgtttgt
     6601 tgactacttc ggcaattttt ggcaatactt caaaggacgc aggacctcca tctaattgac
     6661 gtccaccatg attggatacc cagataccat ctgcccctgc agagatagcg attactgcat
     6721 cttctggcga ttgtattcct tttacgataa ctggaagatg ggtgatttct ttgattgttt
     6781 tgatgtcatc tggtgtcaag ccttgttttg cagctgcata aatttctgcg attccttttc
     6841 cttcgccatt accacttgca ctttgttcgc tatacgcagc taagttaggc attggtaatg
     6901 gaaattggaa ttgattgatg acgtcttctt cacggtaacc accgagcgtt gaatctgccg
     6961 ttaaaatgat agctttagcc cctgcttcta ctgctttgtt caaaatgaac tcattgaatc
     7021 tgtcgtcttt actcatatat aattggaaaa actgcggtgc gcctggcgct gcatcggctg
     7081 cgtctttgat tgtcgtattt gcataagtgc tgatggaaaa gattgatcca gcagcagcta
     7141 ctcctttagc tgtatcagct tccccttttt catgtgccaa tccttgggcc gctgatggcg
     7201 cttggataat cggtgtatct aattcaattc cgaaaacaga tgtatgcaaa tcggctgagt
     7261 cgattccgcg taatatccgt ggcatgattt tctttgtatt aaaagaagtc gtattttctt
     7321 tcatcgtcca ctcatcttca gaaccaccgc gaatatagcc aaaagctcct gcttccatgc
     7381 gctcttttac acgaccttct agttaggcaa tgtttacaat atcgattgga tgttcttcat
     7441 tacttgtatg ataagtcata gtagatcctt ctttcatctt cttgattaca tataaatcat
     7501 actaaactta caaaaagtaa gcaaacattt actctcagat acttttatcg ctattctttc
     7561 caaataaatc gacttacaag ctgatctact tcttggtttt catgaagcat actatgagag
     7621 gcattttcac ctgtcactac tttttcctct atttcatttc cgcgttgctt caacaacgca
     7681 tagaccgcta atgcactgtt taacggtact gttccatcac tcaagtctgt ttcatctagt
     7741 tgaccagcaa tcaagaaaaa tcgagtggtt ataggaatat taccgatcat ttgctggtaa
     7801 tcttgatagc ggttagaaac gacagcaggc ccctttgcta actcatctgt cagagactgc
     7861 gcactatcat cgacaaaatc attaaaaggc gcgccaattg ctgttaatgt ctgaacttgt
     7921 ggcaatgacg tatcctgtcc atacgttcct aaatagcgta gtgcactaac tcctcccatg
     7981 gaatgcccca ctatgttgac tttatctatg ccgtagtttt ctttcagata caaaagacaa
     8041 gttttgatcc attctgcttg attccactcg ttatttttat tatcttcaaa caatacttgg
     8101 accatcggat tgtctgcttt tccagacaaa tctcctgttg cttgtatttg tccatctgtt
     8161 cctactgtta aaaccaattc ttttactgct tgctgatttt tttccaaacg ccgcaacatc
     8221 cctttaaagg aattttctgt cccgctgtag ccgtggaaaa aaagtgttgg aatagtggtt
     8281 ttttctatca ctttactgga ttctgccgtt ttttctttat cagaaacttc agtagtattt
     8341 atcttcgtcg tctggcaacc acttaacgca aacaaactga taaggactaa agctgctgca
     8401 gttgcacgtt tgcataaatt tttgattggt tctgtcatac acctcttcct ttccatatag
     8461 aaaaaagaaa gacttgaaag gccaatcata tgatcgacat ttcaagtctc tttattaatc
     8521 gattttatct acttgatcga aatcaagttc tgtactggtt tcacgtccaa acatatcgat
     8581 gttgactttc aatttttctt tttctccgtc aacttctgtt acttgtcctt ctaatccagc
     8641 aaatgcgcct tcgatgattt tcacgacttc gccaacttct acttctagat cattttgtcg
     8701 caggctcata ccgatagaac gcaagatatg attgacttct tctggaagta atggtgctgg
     8761 tttgcttccg gctccgtgtg aaccaacgaa tcctgtcaca ccaggtgtgt tgcggacaac
     8821 ataccatgaa gcgtctgtca tgatcatttc aacaagtacg tatcctggga atgttttatg
     8881 aacgatttct ttttctttcc catttttgac ttcagtttct ttttcttcag gaacaacgac
     8941 acggaaaata aagtcggcca ttttcatact ttgcgcacga gattcgatat ttgcttttac
     9001 tttgttttca tatcctgaat atgtatgcaa gacataccag tttttttcaa aagattccat
     9061 tgaaggctcc tcatttcatt gtaaaataaa aaaacctcag tacacccgaa gtttttcttt
     9121 cgcttcatta tagcactaaa agtacgttgt ggctagcgag ttattttaaa atccagccaa
     9181 ataagctttg gatggctgta tccattacgt aaaacatcaa tccgaaaata atagaagttt
     9241 cgatgactac taacgtatct ttacggagtt gttttctgct tggccaagtt acttgtttga
     9301 tttcatcttt tacgcttttt agaaatttca tgagacaacc tcccttgcta ctgtttattt
     9361 cgtttcttta tgtaatgtat attgattaca atatttacaa aacttattga tttccaaacg
     9421 ttcgccgctt tttccttcac tgactgattt tgtgtagttg cgagacccac aaacggaaca
     9481 agcgagtgct gcttttttct ttgccattta cttctgcccc cttgctgaga atcagactta
     9541 tacttcataa cagtatcacg taacttttta cttgtcaatt tgtgaaataa actatctatt
     9601 gttttggata aaattatgat atgattaatt tgaaattaag ctaaaatgag acaattggag
     9661 gtatagcgat gctattaaaa acacttgtat ataagaaaaa agatctgaca accgttacag
     9721 agactagtac attagaagaa gcattaaaaa ttttagaaac ttccggatac cgttgtgtgc
     9781 cgatcttaga ttcttcaggt aatattttcc gtggaaacat ttacaaaatg catatctatc
     9841 gtcataaagc aaatggcggt gatatgacgc ttcctgtcac tcatcttttg aaaaacgcta
     9901 caaagttcat ttacctggat acttctttct tcaaagtatt ctttacgatc aaagagcttc
     9961 cttatattgc tgtccttgac agtgaaaatc atttttatgg tattttgaca catagtacgt
    10021 tgcttaatat gctctctcaa tcttggagcg tagaacaagg aagctatgta ctgacaattg
    10081 cttccacagg aaagcaagga gatttggctg ctattgcaaa aatcatttca aaacacagca
    10141 gcattgccag ctgtattact cttgatatcg aaaaagacga atacattcga cgtacattga
    10201 tcacgctacc ggctaacact gaagcgaaag tatgtgaaac gatcgtcaac cacttagaga
    10261 aaaagaatta taaagtggta gaaattgaaa atttgcaaaa ccaagaagca taatcaaaaa
    10321 gcgaaaaaag aaaacagcta atctgctttc ttttttcgct ttttataatt agacacgctt
    10381 ttcaaaatca agcgcgcgat ctaaataata catcaatggt gctgaaacag ccatgacgat
    10441 aaactcactt aatgcaagcg tgccataggt tgtccaaaat gcttggccac ctgttggaac
    10501 taacatataa gcaatcagtc ccatgctgat ggtaaagaag atcgtgttca atactaaacg
    10561 catctttaca tttttcactt tgttttgcaa taaagctgtc aggcctaaag aaagcaatgt
    10621 ttggccgcca ccaaaaacca catccatgat accaaaacca aagaaggcat tatagacgat
    10681 gaccccgcct aaaactcccc aaagcaattt acggttaaag acaactaaat gattcaaact
    10741 ttctgaaata cgaaactgga tcggccctga ggatacaggc gcaactaaaa tagttaacgc
    10801 tagataaaga gccatgatga tgccatttac aacgattacg gataaccgtt gtctgctttt
    10861 cgttttttgc attttctctc ctcttttctc ctagtttttt taacgcggga tggttgatga
    10921 accgcggtta tgtgaaacaa acaataatta taacagactt ttcatttatt tcaatccgtc
    10981 ttatctgctt ttaaaaaagc aaaagcttaa acaatgtaaa cgtttgctaa aaatcgtggg
    11041 atatggtata aagtaagtgt aaggggtcat aagaattccc agtaaagcag acgaagtagg
    11101 atctgcaaga acagaattgt tgtgaaactt aaataaataa aaaaggatgt gggaatttga
    11161 gcaacctctt actagagaac ggtctagcaa gcagctgaag atctaagtgg acatgccgaa
    11221 ccttggaact tctccttacg taagtaatgg atcatgcgct tgctaggctt ttttgtgttt
    11281 ttcggtcttc ggaccttttt cattttccta gacttctgct ataataacca agaattaatt
    11341 ttgtaacaga tttttttgaa aaaacaagtt tctttcattc aaaaaataga aaaagcttgc
    11401 taattattgg ttaaccagca aacaggagta ttaaaatatc ttgttttatt gaatagcagg
    11461 aggaaatcat gaaattccat tatcatatat tgatcaatcc atcggcaggc agcggaaatg
    11521 gctataaagt agcagaaaga attttaccgg tattaaaaaa taagcatatt gactatacac
    11581 ttcattatag tgaatacaaa ggacacgatg ctgagattgc tgaaactttg gcaaaagaaa
    11641 cattgattcc ttggatagaa gaagaacaga aaacaatcga tactttcccc cttttgatca
    11701 tcgtaggagg tgacggcacc ttacatcagg tacttgatac tttctatcag atggaagtag
    11761 aattcccagt tgcttatatt ccagcaggtt ctggaaatga ttttgctcga ggggcaggcc
    11821 ttccaaaaaa tcccaaaaaa ggacttcagc tgattttagc agctcaatca ccagaaaaag
    11881 tccacataat ggcttatgaa gaaaaaataa gtgaaaaaaa aggaatagct gttaataatt
    11941 tcggtatagg attagatgca gctatcgtcc atgcgacaaa tcattcttcc acaaaaaagc
    12001 gattgaacaa atacaactta ggatcatttt cgtatttatt ctctattctc cgtgctttat
    12061 tcactcaaaa aggatttcca attctggtag atgcaggagg aaaacaatta agtttttcaa
    12121 acgcattttt atgtacagca acgaagcatc ctttttttgg cggaggaatc gcgattgttc
    12181 caactgctga tgcgtctaaa ccagtcattg attttgtcgt ggtcgaacga atcaatttct
    12241 ttaaaatctt gtggctcatt cttttactta tacagaaaaa acaattgaaa tcgaaatatt
    12301 tccatcacta cacaacaaac agattacgta tcgtttcaac aacaccgcaa catggtcaag
    12361 aagatggaga agaaatggaa aaacgacctt ttgatatcac aataaccaca actaaacagt
    12421 tgttttggtg ttaataaaag aggttttgtc agaagctaca tctggaacac cgtttattcg
    12481 gaaaaaagga ctgtgacacg acttttgtca cagtcctttt tttactatgc agttaattct
    12541 ttgcccaatt gggttgccat cgatagtttc tttctttacc caaaataaat tggatcattg
    12601 aaaacaccgc agcaaaagca actaagacac aaccattgaa ccaaaaagat tctgcaaatg
    12661 tttgattgta actgagtgtt tcactgatca agttattatt ttgaacaaac caatatgttg
    12721 gtgtgaatgc cgctattttg ctaaccattt ctggcaagta ttctgctggt acaaacaccc
    12781 caccgataaa gcaactgcct gtgataaaaa tatctttgat cccaccgctg gtttctgagt
    12841 tttttaccaa tgaagtgata caagccgaaa agctaatgat cggcaataaa aacaagaaag
    12901 tatttaaaat atgataccat accgttatat cccacgaggt gtggatcact aacagaacca
    12961 ttagaagtaa gaagccactg aacaacagca gcgagtaact aatcaaacta aaggttactt
    13021 tgcgattcaa gtttcgtttg gtaatgggcg cactctggtt tcgtttactg atctctttgc
    13081 gattaaacgc tagattgatg acgctgaaac cgctaaaaat ggatagaaac aacccataag
    13141 acaagaaatt aaaggttgtg cccgtcaaca gctttttcat ccgctgacta tatcccgcac
    13201 ttagctcaac ttctccagta accgagagtg ccatttgtgt ctgttccata gctgcatcga
    13261 ttgttttatc ttcttcttga aacagaatca gtgtttgcaa aaaggtgttc acttgctgtg
    13321 taacaactgt tttagaaaag gcatctgggc gactctgtat cttgatcgtc gccatctttc
    13381 ctacttcgac ttgttcggta aagtctgcag gcagatgtaa gataatgttt acacgattaa
    13441 aataaagagc atcatcgatt tctttttgtg aggttccatc caatgtaacg actgtttcct
    13501 tgtcattcaa atatttacga aggccatcga ctacaggcga ctcttcttca ctaatcaagg
    13561 cgattttcgc atcttgcaga gaggtatttt caacatcaat attttgcgca aaaaagaatg
    13621 tggcaacaac agtgataatt acacctatca gtaaattcga tttatttgct ttaagcaatg
    13681 tccaaatcgt tttataaagc gtcataacgc acccctcttt ccatccaagc atttcctaac
    13741 gcaaaaagga aaataaatcc gatcaaccat agaagattgg tataaaaact agccaaatca
    13801 gtgtagaaat aaagtttata caaactttcg ctgatcaagt tgacgagatt taattgacca
    13861 acaatcggaa tatgaagatc aatccaatac ttcacttgtt ccgaccccat cataccagca
    13921 aaaaagctca tcgcaatcgt cactgaaatc aagatgctat ccttttgcac cagattcatt
    13981 tttggtatca aattaccaac caatgtacct aacaaaatcg cacacaacga ccccagagcg
    14041 gtaacaatca tcaaccattg ccaacgttca ccaaagtcta cttgatagat aaaacgaaag
    14101 acagctaaca taatataaat ctctgtcaaa acaatcgtaa agcttgctgc caaattagcg
    14161 attgaaacta acgattgctt tctaggaatc aaggacaagc gaataccatt tgacgattga
    14221 tttgcttgct gatcctgtac attgcggacc ccccacatcg tcccgtagag aatcgccatt
    14281 ccaatcagag tgaagaaata aaaacttttg aaactcatat tacgacctgc atgaacttct
    14341 tgaaaagata cttcttgttc aaaaacagtc atgatgggcg cgagatcaac gttctccact
    14401 tctgccactt tactcgaaat tataccaata cgctgtaaaa attgatccat gacgtttttc
    14461 atcaacgtct gactcattcc tgcttgaccc acatggagcg aaacagatga accatcaatg
    14521 agataaaaac cagccaaatc atctgcattt agcttttcat tcgcttctac ttccgatagt
    14581 tcctgtactt caaataatgg tttatcattg acttcgactt gttctaagac tgtggtaaaa
    14641 ttttccgaaa gcgctgtttg atccgctttg attacaattc cagtattaat cgtttcaaga
    14701 ttgccacctt gatcaatctc gccaaaggcc gccataaaca tcaatcctaa aagaattgga
    14761 aaggccaatg tccaaaacaa catggattta tttcgcagca gtatttttgt gcgatattta
    14821 taaaaatgcc aaaacattat ttcccctcct ctagtctctc aaatccttgc cagtaatctc
    14881 taaaaagaca tcattcaagg acgcttcttt ggttgctatt tttccgtaac tgatcttttc
    14941 ttcttgtaag attgtaagaa tcggcaacaa tactgtattt agttcagtag ttgttacttg
    15001 gagctgacct tttttataag cgattccatc agaagctatt gttcgctgaa tcgctgacaa
    15061 cacattttct gggagtaatg ggatgtcgat cgtcaaacga tccgccgtcc gtaccatatc
    15121 ttttagagat tctttggttc ctttagcaat cacctgtcct tgatccatga tcacgatctg
    15181 gtcgcaaaga atttctactt cttccatgta atgtgttgta tagacaatgg ttgctccttg
    15241 tcgattcagc tccttgatac tttctaaaat tttattccga ctttgggggt ctacagctac
    15301 tgtcggctca tctaaaaaaa ttaaccgcgg cttgtgggca atcccacatg cgatgttcaa
    15361 ccgacgtttc aagccaccac taagttctcc tggacgaaac gaaacatatt tttctaatcc
    15421 cactaattga atcacctctt caatcaaggc tttccttttc tctttttcgg aaacatataa
    15481 accgcaaaaa taatcgatat tttcttgcac acttagttcg tcaaagaccg caacgtcttg
    15541 aggaacgacc ccaatcattg ccttgacagc ataattttca ggagtcattg ttgtcccgaa
    15601 caatttaatg gttcctttgt cataatttaa caaagaaagc atacagttga tggcagtcga
    15661 tttcccactg ccgtttggac ctaacagacc taagacttct ccttcttgta cttgcagatc
    15721 aaaatgattc aatgctacaa aatctccata gcgtttgact aatttatcaa tttcgataat
    15781 catcatgaaa aactccttcc aaatttcttg ttgatctgac tataataaag tgcaagaaaa
    15841 gaaactagtg acgattggct aaaccacaca tgacatttgt cacaatgaag gagtctgcta
    15901 tgcataaatc tcggctactc aacgaaacta gctttctact ggttatctca ttgcttttgc
    15961 tggtaagtca aggattcgtt gctatgcaag ttatctattt attgatcgcc gttttattca
    16021 ctggtgtcag ttatttactg cctacaaagc caaattggat tttccaagtt attctatttc
    16081 ttttatgtgc ctttttacct gatcttgtcc tgtttctgcc agcgacgatg cgagtgatcg
    16141 cccctgaaga aagccacctt gattacttgt ttttgttagg ttttttgttg atttcgacgg
    16201 ttggtaatca tccccccatc aaggtcgcct ttgtcgtaat tttgctgttt ttttcctttt
    16261 acttacgaaa aaaagatcaa cgaacgaccg atcttgagaa aaagtacatt gtctccaaag
    16321 atactcattg ggaaaaacaa caagagttat cggaacaaaa taaagcattg gccctgtcac
    16381 aagaaacaca attagccttg caaattgtgg aagaacggaa ccgaattgcc cgagacatcc
    16441 atgacaatgt cggtcatctg ctgtcaagtg cgattttaca aattggtgcg cttgaaatga
    16501 tcaatcaaga accaaaacta aaagaaccat tagaaaattt aagtgccacc gttcacactg
    16561 ggatggatcg gattcgtcaa agtgtccatg acctccatga gacatcgatc tcttttcaac
    16621 actccttaga gtttctgatc gctgattttc cttcttctgt tacgattgaa ggaaacttgt
    16681 ttgaaggatt gaatgaaacg cagcaaaact gcttcttaat ggtcatcaaa gaagccttaa
    16741 ccaacagtat caaacatagt catgccaaaa ccgttgtttt acattttcga acgttgccgg
    16801 ccttttatcg cttgcaaatc acgaatgatg gcaccagccc acaaaaaaat tctgctcccg
    16861 gtattggttt gaaaacgatg cgtcaacgtg ttcaagaaca aaagggacaa gtccatattt
    16921 tccaagaaaa ccagcaattt cagttaacga tcattttacc aagggaggga caccaatgat
    16981 aacagtagtc attattgatg atgatccatt tgtgacgaaa tcgttacaaa ccattttaga
    17041 aagcacgaaa gagatccgtg tgttaggcat tggtcattgt gccaaggatg cgctagtctt
    17101 atacgaaacc catcgtcccg atgttttgct gacggacatc cgcatgccta aacaaacggg
    17161 catcgatgct gccaaagaaa ttttggctaa atttcccaaa gccatccttt tgcttttgac
    17221 gacattcaaa gatgaagaat acatccgcga agcattttcc atcggtgtca aagggtattt
    17281 aatcaaacag aacttgcaag cgattattcc ttctgtcaaa tccgcttata atggacaggc
    17341 cgtatttggt aatgaaatca tcgagacttt cactcaaatg atgaagaata aaccgacgat
    17401 tgatagtcat gcttatgctt cttttagtga acgtgagctt gcaatcatca aagaagtagc
    17461 tgccgggaaa aacaataaag aaattgcaga tgccttgtac ttgagtgacg gcactgttcg
    17521 caattacatc agccaattac tagaaaagct agatttacgg gatcgcacgc aattggctat
    17581 ctatttttat cagcatttgc aataagtctt atctaacaca aaaaaacctg aatgatgctc
    17641 cttcgcatca ttcaggtttt tttcacatct tctattcaat tgtcccgcaa accatttcct
    17701 cacgattgaa agaatcaagg attcgcaggg ctgccaggat tcgttggatt gttcggcgtg
    17761 ttaggcggaa aaataggcgc cttgtctaac gttttttcta gttttgattc ttcacgatcg
    17821 tctcgttcta catcaggact ttcattcaat ttgaattctt tttccatctc atctaacttt
    17881 ttaaagtcat tgccagattc ttttgctaat ttcgctaatt tatcttcggt ttctttagcc
    17941 ataaagtaac gccccccttt tgatttcagc ttagcatatc acactgaaaa aacaaaagaa
    18001 aacgctaacc aacgatcatt tttagctatt tctcatcttt aaaatcaagc attttttgcc
    18061 ggtataaaat cgtagggaga actgttttcc ataccaatca tcggatctac taactggtta
    18121 tcgatcactt ctgctgtaag aacgaaatct ttagaaacag caggttctac ctcttctttc
    18181 ttttcttctc caacaaatga agaaaacaga tctggttcca ctgtttccat tacttggttt
    18241 ttcgtttcat tcgtcccact gtcatcttct acaggtagct tttcttttac aacccgtggc
    18301 tcttttgtat agttcccatc ttcaaatgga tcatttccga ccaaagaatc ttcataagct
    18361 gctagtttgg tccggagagt gatattcatt ttatcattat ccatgatcct tgatttcaac
    18421 gtagtcatcc ggcttgctga ttcattcgct acacaagtga cataggcttg ctcttcccct
    18481 aacaaaatca acagttcctt actgcgagtc actgccgtgt agagcaaatt acgctgaagc
    18541 atccgctgat attgatggac catgggcaaa ataaccatct tgaattcact gccttgtgat
    18601 ttatggattg agcaacaata agaaagagtg attttattcc attcgtttct tttataagtg
    18661 acctcatttg catcaaactg gataactaat tcatccactt tatcttcaga atcttttgcc
    18721 aagatgatac ccgtgatttc tcccatatct ccattgaata cattcaattc gggagtattg
    18781 actaattgga ggactttgtc tcctatccga taaacggtgt cgttccaatg tacttccttt
    18841 tttccaggtt tccctggatt gaatatctcc tgcatcattt tatttaacgc atcgatccct
    18901 gcaggtcccc gatacattgg tgctaatact tggatatctt gtgcacggaa tcccttattt
    18961 ttcgcttttt ccacaatttt agagatcaag ggttcaattt gataagcatc acttcggaaa
    19021 taggaacgat ctttttgatt ctttgtgaaa tcttttggca gacgtccttc tttgatctca
    19081 tgggcaagag gaataatact agaaccatca ccttgccgat aaatctgatt gagttccatt
    19141 ttgggaattt gttcgatttc caaaagatca tggagtactt gaccaggacc gacagaggga
    19201 agctgatctt tgtctcctac taagataact tgcatattcg tcggaatcgc tttgaataat
    19261 gtgttagcca gccatgtatc gaccatagac atctcatcaa caatcaaaag tccgccttct
    19321 aattctttcg tactgactga aggtgttttt tcccgtccat tcagccccag aagacgatgg
    19381 atcgtactgg caggcagacc tgtcgtttcg ttcattcgtt tagctgctcg gccagttggt
    19441 gctgcaagta gaataggaaa aatttcttgg gtatattttg aaggatccaa ttccagtccg
    19501 ttcaactctg caaaaagatt gacgattccg ttgatcacag tagttttccc cgtacctggt
    19561 cctcctgtta aaataaatag aggggaacgg attgcttcag cgatagcttg ttcttgcgaa
    19621 ggtccatact gtatgccgaa tattttttcg atacgccgaa tattcttctg cacttctttt
    19681 tcaggataat ggatttcttt tttacgactg agaaggcgct ggatcgaatt accgatcccc
    19741 cattcagaaa agtacaaact gttttcgtaa agattagtct cttcttgttg tatctttcct
    19801 tcttcaacaa gttggataat tacagtagca acctgatcag gctggatttc aattgggcga
    19861 cttgtttcta aaatacggat cgtttgctga agcaatgtct ccgccggtac gtatgtatct
    19921 cctgtttgaa ctgcatgctg aaaaatctga tgcaagatag ctgctcgaat tcttctcggt
    19981 gaatctgctg caataccgat ttgttcggct agattatctg cacgtttgaa cccgattcct
    20041 tctatgtctt cgactagctg gtacggattt tcttcgatga tatccaaaga ctcgttctta
    20101 taggcctggt agatactgaa agctaactga ctaccgaacc cgtaacgatt cagtcccatg
    20161 atcacttgat ccatcccgtg gtttagccga atcgtctcag caagcatttc tctttttggc
    20221 ttcgtcaaac cggagatttg ttttaatacc gaaggatcag caatgatttt ttcgatagca
    20281 tcttctccca gcaattctac aattttttct gctgttttct tcccgattcc tgggaatttt
    20341 tcgctggaaa gatacgctac gatcccattt gcagttgttg gcttttcttg ctcatatctt
    20401 tcgagtttaa gctgccttcc gtatttagga tgatccacta attctccata aaaacgataa
    20461 gtctcatttt cttgaatatc gccgaaactt ccggtgacta caatctcttt ttcacggtaa
    20521 tcagctgtgg tttcactgat gtgtaccaaa agcactttgt aaaaattact aggattttga
    20581 aaaaaaatcg cggcaactgt accaacgaaa taaggcattt cttctggctg catcggaagc
    20641 cgcctccttc ttctatagta aaggttctgg tgctgtttca gttcctaaaa aatctgtttg
    20701 gttccatact ttcagttcat atggcaataa tctgcaaggc tcttcagtct ctaaaatcgt
    20761 caaactacta ttgaacaatc cacccatttc acgcaactca cttagctctt ttcctgtcat
    20821 ccattgaatg gctgcagtta aagaagctcc atgtcctacg aataaaagtg ggccatcttt
    20881 atgtcgggca accgcatctg ctacaacagt ttcgatacgt gtgattgccg attcaatcgt
    20941 ttctccgtga aaaggagaag gatcatacag atctaaatga ttacgcaaat tcggcagatt
    21001 atccggatat ttctggtaca tttcatcgat cgactgacct tctaaagtac ccagccctag
    21061 ttctcttagc ttatctgtat aaaaaatctc taccggacga gcaagctctt tgttgatacc
    21121 ttctgctgta tcacgtgctc gctttgctgt actggaataa attgctttaa aaggaacata
    21181 ttttaccttt ttcccaaatg ctttgatttc ttcgtaactt tgtggcaaaa gcggagaatc
    21241 gccattgctc ccttgaaaac gtctttcctg attccattgt gtcttcccat gtcgggtaaa
    21301 atatagttcc atacgcagca aactcctgtc tttcttttat tttactctat aataaactgt
    21361 ctaatccagc ttgtcatttt catagtgatg cgtcaattct aaattaggga atccttgctg
    21421 gcgaagtgct tcatacacta tcattgcagc tgtattcgat aaattcaatg agcggacatg
    21481 ctcatcattc atagggatgc gtaaacactt ttcttcgttt tcacgcataa atgtttctgg
    21541 caaaccggtt gtttcttttc caaataaaaa gaagtgctct tctccatcag caaaattttc
    21601 gtcactatat actttatggg caaattttga gatcaaatgt agtttacgat tacctaaaaa
    21661 tgttaaaaaa gcttctaaat tactgtggta agtaatattt acatcattcc aataatccaa
    21721 ccctgcccgt tttagatgtt tgtcatcagt tgaaaaacct agtggctcga ttaaatgaag
    21781 cggagtattc gtggctgcac acgtacgggc aatatttcca gtgtttgcag ggattaatgg
    21841 ttcaaataaa acgatatgat tcatcaggat cattcctctc atatttatgt tcgtttctat
    21901 tttctgacaa tttgattttt gcataaaaaa aaacgtatca actcggtgtc agtcactgcg
    21961 agtcgttacg ttagtgaagc tcttctcact aacttttatc agaacaggaa cctgataaaa
    22021 accaatgaaa aaacaacttg ttgctaatat aacaccctca actttttttt gcaacctcta
    22081 ctcattaaaa actgctagaa aaacgttttc tcttagttcc ttttaataat tctatgtcaa
    22141 ttgtaatctt cttcaaagga ttcttatata agtctgcttt gattcgctct tctacctgcc
    22201 attctaaagg tgacatggcc aaaagatctt tttgattttc ctctggtatc tcaaattcat
    22261 aggttacacg ctgacgttca gttaatttca ttgcttcagc aaacttggct actacacgtt
    22321 cattggaata actctgtttt tcaggttgat tcggataaaa agcctgacgt agttccttta
    22381 aataattttc ttgtggcacc accttcaaca cttctccatc ttctgagagt acacgttgga
    22441 attcttggta atgagaaggc gaaaagatat ttaaaaccgc gttgaatgtt tgatcagcaa
    22501 acggcaaatt ggtcaaatca gctacacacc aaaatgcttc ggcagattgt tctgtagctg
    22561 cgtagactcc ttcttttgaa atatcaaatc caacagcatt ttgaatcttt ttcaattttg
    22621 aaagttcatt caagaagcta ccttctccgc agccaacatc taatagcgag acttcttcag
    22681 gtaaatgctg cgcaatagtc tcaataacgg gctgatacat gccagattgg atcattctac
    22741 gccttggaac gaacattcct tgatcgtatt ctgttttaac cgcatgggat aaaaaataaa
    22801 gtgttccttt tttggaaagg tcaaaacggt gattattttt gcatatcaag ccattatcag
    22861 acttttttac ttcttcttgg caaaccggac agcggaacag ctgatgattt tctgccaaaa
    22921 actggcgtcc tcggtcaatt ttttttaaca tagttccccc tcatttctgt tttatcttac
    22981 cgttagatgc tcactttggc aactgctaaa aatatgatac aatgcctaga agaaagtgaa
    23041 agataaagga gaagattaga tgatcaaaga attttgcgct gaaaactaca catctattcc
    23101 tctagcaatt gctagaggag ccgatcggat cgaattgtgt gacaacttag cggtcggtgg
    23161 cacaaccccg agtactggtg tgatcgaaga aacgttaagt tatgctgggg aaaaagatat
    23221 ccccgtaatg acgattattc gtcctagagg gggcgacttc gtctataacg atatcgaatt
    23281 gaaaatcatg catactgatt tgattgaagc aaagaaatta gggacggatg gcgtagtatt
    23341 tggttgtctt actccttcag gctggctaga cgaagaggcc ttagaactat tgatcgaaac
    23401 agcagaaggg ttgcagatca ccttccatat ggcttttgac agtattcctg aagatcggca
    23461 attcgaagca atcgattggc tggtagaaca tggtgttgac cgtatcttga ctcatggcgg
    23521 tcctgctgac aaaactattg tagaaaattt cccacggctt aaagaattga ttgcctatac
    23581 agatggccgc ttaatcattt tgcctggtgg tggtgtcact gcagagaatg cagcacatgt
    23641 agctaaagaa ttgaacgtaa gcgaagtaca cggaaccaaa atcgtggatc ttcagttata
    23701 atcttataaa caaaaaaaca tttgcaacag gcataatgct tattgcaaat gtttttgttt
    23761 ttttacataa aatagcccat aaataaagaa gcaatattga aataaatcag tacactcgtc
    23821 aaatcgctca aagtcgtgat aaagggaccg cttgctactg ctggatcaaa tcctagacga
    23881 tccattagca tcgggattaa actacctgca agattcgcca ctgtgattgc aaatagcata
    23941 gccatcccta tgacaaaccc caagataaaa ttatgtttcc aaaaacctac gattagaaaa
    24001 atcgtgatcc ccgtaacagc tcctgtgaca acgccggtca agacttcagc caaaacaagt
    24061 cgaacaaatc catgatcttt ctcatcagaa atcgcaagtc gacgaacagc cacagctagc
    24121 gactgggttc cagcattacc ggcagttcct gtaatcagcg aaatgaagac tgctaaaata
    24181 ctcgcttcac ttaccaagtc ttcatagtga ctgattaaag aagcggtcga catacctaaa
    24241 aacaacagag tgatcagcca aggcaaacgt cgagacgctg cctttactgg attttcatta
    24301 atttcttcca cattgacccc ggcaagtcct gaataatcgc tagcagcttc atcatcaata
    24361 acgtcgatga tatcatcgac tgtgacgatt cctaacaaat gatcatcata atcggtaaca
    24421 ggaagagcta agaagtcata atctctaaat gtttgtgcca catcttcttg gtcgtcgcct
    24481 acatgaactg aaagcactcg ttcgctcatc agatcagaaa tcattgcgtc gtcatcattc
    24541 acgattaggt cgcgcagaga aataacccct actagctgac cttcttgatt aacgacatag
    24601 atgtaataga ttgtttcagc tacatctgct tcgttcttca gcacgtacat cgcagagcga
    24661 acagtttgat tggctacgat cgaaacaaat tcagttgtca tgatcgcgcc agccgtttca
    24721 tcctcgtaat ggagaagttc cttgatttca ctggcatcgt ctgccgacat caaacttaaa
    24781 tatttagcaa tttgcttttt atccagcgta ttaagcaagt caacagcatt atctgtatac
    24841 atctcagaaa gcatatcagc tgcatagcta ggacgcattt catctaggta ttctttcata
    24901 tgttcgttgt cttcttcaat cacatcgaac atatccgcta attctttagg cgacagatag
    24961 gaatagatca gctgcctgtt ctcttctgta agagattggt agaattgccc ctgctcatag
    25021 atatgcatct ctaaaaaact gtttctgaat gcctgaatat tattttccct taaatcttga
    25081 gtcaactggg caaatctttc ctctaattct tgattttcat ccaaaccaat ctcacctcgc
    25141 cttattcttc aaaccgtctc acaactgcct ccatgtctgc ggctaaaggc tgcttgaact
    25201 ccagcaactc ttctgtaaat ggatggtaaa aacgcagatc ataacaatga agggcttgtc
    25261 tttttattcc cagatccatt cgcccgccat acatatcatc accgagcagg gcacagccaa
    25321 ttgcggaaaa atgaactctt atttgatgtg tccttcctgt atgcagctgg atatcaacta
    25381 acgcgatttc tgttagtcgc ttctctatcc agtactcagt ctgtgccgaa cgtccttcat
    25441 cagagaccat tcgcttcaat agcgaagaat aatctcgggc gatcggcaaa tcgatatgtc
    25501 catgtgccga taaatctgaa agccttccac tgactaaggc ctgatatttt ttcacaaact
    25561 tcttttcacg aagttgcata tctaattttg cgtgcgcaaa tccatgcttt gcaaaaagca
    25621 tcaagccaga tgtatcccga tctagtcgcg tcaccacatg gattacttgg ttttcgtaac
    25681 cttgtttttt ataataagcc tttacacgat tagccattgt cccatttgga tggtattggg
    25741 caggaataga cgaaacgcct gctggtttat ttactaccag aacgtgttca tcttcataca
    25801 cgatatcgat cggtgtttca tccaaaagta cggtttcatg ttctccttca gcaggaatca
    25861 caatggttac cttatcatcc ttagctagag aaaacaagac attttctact tgatcattaa
    25921 ctttgatttg accgccttga aattttattt tcgctaacag accctttgag atcccttttt
    25981 cttttaaaaa atattttact tgctgagaat gatctttctc ataatcccat gtaaactgca
    26041 tatcaatcct cactaataaa ggcatctttc acacgatgcc aaaaatgcat atgtcgataa
    26101 gaagcaaaat ggatccgttc ttctgctatt cgataataaa ttgagcggat atttgctttt
    26161 gcgacattca attgatcaac cgttacaaga taatcttctg tattttccaa ttttatttct
    26221 agccattcat catgggcaat cacgatcgga gaacccaaag tacgaaacac tcgattattc
    26281 agtgaagcaa tctctgccaa ctgaaaggca ttgatactag gatggatcac agcaccgccg
    26341 acacttttat tatatgctgt cgaaccagta ggcgtagaaa tcgtcaatcc atctcctcta
    26401 aaactttcaa acagctcgtt tttgatgtat acatcggcta ccatcgtacg attggcccgt
    26461 ttaatcgttg attcattcag tgctaaaaaa tgctggtccg gtgtttcatc caaataactg
    26521 atccgaacat ccagcaaggg ataactaaca ctttgttccc ggttcgttcg taagctgtct
    26581 actagttctt ccagctcgta atcccgccaa tccgtgtaaa accctaaatg acctgtatgc
    26641 acgcccaaga aacgcacatc attcagacaa tgactgtagt gatggaacgc cgacaataat
    26701 gtgccgtctc cgccgactga gatgaccaat tctggctcat gatcatctcg ttgaatccct
    26761 gcttgttcta aaagtgcgtt caaacgttct gtcacttcta tagtctttgc ttctttatta
    26821 tgaacgatcg ctactttcat cccctgcctc ctctctttcg ctttctttct tcaaaagcgt
    26881 tcgatagtag acatcatctg attttcctct tccatgggag aataaccgct gtgcttcttg
    26941 gatttcttca cggatactgg acatctcttc atccaactga taggcagctt ctgccgcacg
    27001 ctgaagtcgt tcactcattt cttctggaaa aacgccttga tatttataat tcagcgaatg
    27061 ctcaatcgtt gcccagaaat tcatcgcaag agtccgaatc tggatttccg ccaaaatttt
    27121 cttctcaccg ctgatcagct gtacaggata ctcgatcacc agatgataag aacggtagcc
    27181 acttgctttt ttatttgtga tgtaatctcg ttcttggaga actttcatgt cttttctttt
    27241 acggatgatc tcaacaactt gatggatatc ttctacaaac tgacacatga tccttaaccc
    27301 ggcaatatca gacatttctt cttctaaacg tcccattgga atatgccgta attgtgattt
    27361 tgttacaata ctatcgactg gcttgactct cccagtgaca aattcaatcg ggacatgtcg
    27421 attttgttca cggaactgtt tgcggatccc ccgcagtttc actttcaatt ctgatacagt
    27481 ttgttcatat ggtgctaaaa atgcttccca atctcgttcc atagctgata cctctacttc
    27541 attaacattc attgtttatt ctaccatata tgcaaagttt tttcgtactc ttgatttatg
    27601 cattgaccaa aaaaagaaaa ttaggcaaaa tagacaaaaa ggagtcgatc aaatgacaca
    27661 aatgcttgaa atcgaatata aatctatgct gacaaagcaa gagtacgaga tattcatcgc
    27721 tcactatcaa ttaacagata aagatttccg tgtacagact aatatttatt tcgataccgt
    27781 tgatgaacag ctgaagaaac aaaattgtgg cctacggatc cgtttcgttg gtcatcaagc
    27841 tgaatataca ttaaaaacac ctgctgaaaa agggcgtctc gaaacaacgg atacctttat
    27901 aacagaagaa gcagaagcat ttatcttcga aaaacgtctg cctcgttcag gcgcagtttt
    27961 tcaaaaactt tctgatttga atatcgatcc tgcttcatta atccaaaccg gaaagcttac
    28021 aacaaaacga gctgaattcc ctattgaaga aggactttta gctattgatg aaagctgggg
    28081 agacaatcta cacgattttg aactggaact agaggtaggg gatgcatctg tgggaaaaat
    28141 tgcttttata aattttttaa aacgtttttc tttaccttat cgtcctgcta agaacaagat
    28201 ccaacgtatg cttgaagcta aaaattagaa acctttcatt ttcacaaggc acttgagttc
    28261 atttttttac ttttttctgt taagttatag gatgtgaaag aatctagtca ctagttgtat
    28321 agaatctatt ttgggggaga ttcatatgat cgaaatctat ttatttgtta atcctttagg
    28381 ggaatactgt ttcgaaatgg aacaacagtt attacaattt atcgaagaag agtacgggac
    28441 accatcaaaa gaaaagatgc aatttcgctt tcttcctttg gtcaatttgc agacaattgg
    28501 ggatgtcatg caacaaaaag gaatttctca gaacaatctt gaggaacgta atcacttatt
    28561 ctcaatgact tattctgcag cattggactg caaagcggcg cagtttcaag gaaagaaaaa
    28621 aggccgccgt tttttgatca aattgcaaga agcagtcggc tgtaatgaca taccatattc
    28681 tcaagaactt gctgaatcca tatttgaaga aatcggcggc gatttgaata tgtttaaaga
    28741 agatcgtcag tctgacttcg ttaaagaagt attcttttct gatcaaaaaa ttgctcggga
    28801 aatgggcatc acaaaacacc cttctgcagt cgtttacaat tatgcctgcg accgtgattt
    28861 tggtgtttta gtagaagtaa aaggtacaag tagcctttgg agaatcacag agctgtgtaa
    28921 aacaacagat aactcatatc aagtttttaa tggtgaacat ttacatacaa atgattctca
    28981 gttccattca agaactagcc atttacactt gctttctaat ta
//
LOCUS       DACDLM010000032        28600 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.032, whole genome shotgun sequence.
ACCESSION   DACDLM010000032 DACDLM010000000
VERSION     DACDLM010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.032"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            237..1877
                     /locus_tag="IV356_001476"
     CDS             237..1877
                     /locus_tag="IV356_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HAP9015168.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAVFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            2031..3353
                     /locus_tag="IV356_001477"
     CDS             2031..3353
                     /locus_tag="IV356_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HAP9015169.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(3415..3846)
                     /locus_tag="IV356_001478"
     CDS             complement(3415..3846)
                     /locus_tag="IV356_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP9015170.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(3910..4746)
                     /locus_tag="IV356_001479"
     CDS             complement(3910..4746)
                     /locus_tag="IV356_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HAP9015171.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQAIVIVVLLINLYNAFVILQTLEGSGFKQVKITEKSF
                     FK"
     gene            complement(4936..5238)
                     /locus_tag="IV356_001480"
     CDS             complement(4936..5238)
                     /locus_tag="IV356_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HAP9015172.1"
                     /translation="MTEHNHSHEHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEE"
     gene            complement(5264..5695)
                     /gene="ruvX"
                     /locus_tag="IV356_001481"
     CDS             complement(5264..5695)
                     /gene="ruvX"
                     /locus_tag="IV356_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HAP9015173.1"
                     /translation="MRVMGLDVGSKTVGVAVSDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(5692..5958)
                     /locus_tag="IV356_001482"
     CDS             complement(5692..5958)
                     /locus_tag="IV356_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HAP9015174.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(6212..6937)
                     /locus_tag="IV356_001483"
     CDS             complement(6212..6937)
                     /locus_tag="IV356_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HAP9015175.1"
                     /translation="MSKKTTKAIVGIVAAVIAGALGISTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(7303..7373)
                     /locus_tag="IV356_001484"
     tRNA            complement(7303..7373)
                     /locus_tag="IV356_001484"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7339..7341),aa:Gly,seq:ccc)
     gene            7490..8242
                     /locus_tag="IV356_001485"
     CDS             7490..8242
                     /locus_tag="IV356_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HAP9015176.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            8258..8737
                     /locus_tag="IV356_001486"
     CDS             8258..8737
                     /locus_tag="IV356_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter"
                     /protein_id="HAP9015177.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(8988..10568)
                     /locus_tag="IV356_001487"
     CDS             complement(8988..10568)
                     /locus_tag="IV356_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HAP9015178.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(10561..11304)
                     /locus_tag="IV356_001488"
     CDS             complement(10561..11304)
                     /locus_tag="IV356_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9015179.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KRLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(11480..12256)
                     /locus_tag="IV356_001489"
     CDS             complement(11480..12256)
                     /locus_tag="IV356_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP9015180.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(12504..13340)
                     /locus_tag="IV356_001490"
     CDS             complement(12504..13340)
                     /locus_tag="IV356_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HAP9015181.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(13351..14280)
                     /locus_tag="IV356_001491"
     CDS             complement(13351..14280)
                     /locus_tag="IV356_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HAP9015182.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            14472..14825
                     /locus_tag="IV356_001492"
     CDS             14472..14825
                     /locus_tag="IV356_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAP9015183.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(14899..15555)
                     /locus_tag="IV356_001493"
     CDS             complement(14899..15555)
                     /locus_tag="IV356_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAP9015184.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            15781..17715
                     /locus_tag="IV356_001494"
     CDS             15781..17715
                     /locus_tag="IV356_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP9015185.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(17801..19024)
                     /locus_tag="IV356_001495"
     CDS             complement(17801..19024)
                     /locus_tag="IV356_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronyl hydrolase"
                     /protein_id="HAP9015186.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(19018..20916)
                     /locus_tag="IV356_001496"
     CDS             complement(19018..20916)
                     /locus_tag="IV356_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HAP9015187.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(20910..22028)
                     /locus_tag="IV356_001497"
     CDS             complement(20910..22028)
                     /locus_tag="IV356_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAP9015188.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(22111..22944)
                     /locus_tag="IV356_001498"
     CDS             complement(22111..22944)
                     /locus_tag="IV356_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP9015189.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(22937..23854)
                     /locus_tag="IV356_001499"
     CDS             complement(22937..23854)
                     /locus_tag="IV356_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP9015190.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(24081..25205)
                     /locus_tag="IV356_001500"
     CDS             complement(24081..25205)
                     /locus_tag="IV356_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP9015191.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            25388..26296
                     /locus_tag="IV356_001501"
     CDS             25388..26296
                     /locus_tag="IV356_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP9015192.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            26437..28050
                     /locus_tag="IV356_001502"
     CDS             26437..28050
                     /locus_tag="IV356_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HAP9015193.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT         8889 a         5621 c         4868 g         9222 t
ORIGIN      
        1 ttctatttat ctatctaaca tatcctttat tcttctactt ttctttcttt agcatataag
       61 agatacgcat agtaatcaag caaggattgt tgatataaaa agaacaaata ccgctatttt
      121 gatttctttt gactctatta ctcatataaa taaaatttat tatacctgct ctttttgact
      181 atatcctcat ctgactccta tacttcgttt gtattaaaac ttaggaggaa tcattcatgc
      241 ttacagggct aaacttatta aataatcctt ttctaaataa aggaacagct tttacaaaag
      301 aagaacgggc aaaatacgga atcactggta tgcttccaag tactgtccaa acattggaac
      361 aacaatctgt ccaagcttac ggtcaatact taagcaaaca gaccgatttg gaaaaacgta
      421 tcttcttaat gaatctattc aatacgaacc ggacattgtt ttataaattg atgggcgaac
      481 atttagttga attcatgcct gtcgtttatg atcctgtcgt tgcggattca atcgaacaat
      541 acaacgaaat tttcttgaaa ccacaagatg ctgtatttct ttcaatcgac gaaccagaaa
      601 atatcaaagc aagtttgaaa aacgcagcag atggacgcga cattcgtttg atcgttgtga
      661 cagatgcaga aggaatctta ggtatgggtg actggggtgt gaacggtgtt gacatcgcta
      721 tcggtaaatt gatggtctac actgccgcgg ctggtatcaa tcctgcacaa gtcttgcctg
      781 tatcaatcga cgctggtact aataacgaag aattattgaa taatccatta tacttaggga
      841 atcgtcatgc tcgtgtagaa ggcgaaactt actacgaatt cattgatcaa ttcgttcaat
      901 cagctactga attattccca gaattgttat tacattggga agattttgga cgaggaaatg
      961 ctgcaacgat cttagaaaaa tacgaagata aaatcactac tttcaatgat gatatccaag
     1021 gcacaggaat cgttgtacta gctggtgtat taggtggatt gaatatatca ggtgagcaat
     1081 tgaaagatca aacgatcttg acatttggtg ctggtactgc tggtgtaggt atcgcaaaca
     1141 tccttttaga tgaaatgatc cgtcaaggtg tacctgaaga agaagcacgc caacatttct
     1201 atcaagtaga taaacagggt ttattgtttg aagatacaaa aggattgact cctggtcaaa
     1261 tcccattcgc tcgtaaacgc tcagaattca ctaatgctga tgaattgaca aacttagaag
     1321 cagttgtaaa agcaatccat ccaacgatca tgatcggtac ttctacccaa cctggagcat
     1381 tcactgaaga aatcgtgaaa gaaatggcgg ctcatacccc acgtccaatc atcatgcctt
     1441 tgtctaatcc aacaaaattg gcagaagcaa aagcaaaaga tttgattgaa tggacggacg
     1501 gaaaagcttt agttggaaca ggtatccctg ctgctgatgt ggaatataac ggtgtaactt
     1561 accaaatcgg tcaagcaaat aatgcgttga tgtacccagg tttagggctt ggtttgattg
     1621 cttcaacagc tacacgagta aatgctgaaa tcatttctca agctagtcga gcattaggcg
     1681 gaatcgttga tgtaacaaaa ccaggagcag ctatcttgcc tccagtagca aaaatcactg
     1741 aattctctca aacgattgct gaaactgtcg caaaatcagt tgttgcacaa aaattgaatc
     1801 gtgaagaaat cacggatatc aaagaagctg ttgaatctgc taaatgggtt cctgaatata
     1861 aatctttaga agattaagat tgttatagta aaagaacata cagaaacttt gtatgacgtc
     1921 taaaaagaaa aaagcgactg cggcaaaaca gcagccagcc aactactgct cttttgccgc
     1981 ttctctttgg cttttttcat acgatacaga ataagaaagg atctgtaaaa atggcacaaa
     2041 aaacaacaac cgcaactgca gttgaggaaa agaaaaaaga agggttttgg tcaacaaaaa
     2101 ttaccggcgt aagtttgccc ctttatttga tcatggtcct tgtcctgatc attgcaatgg
     2161 ctttaggaaa attaccgacg aatatgattg gcccaatcgc tgttttggtc attttcggta
     2221 atttatttca ttttatcgga acaaaaatcc ctatagtcaa aagttattta ggtggtggct
     2281 ccgtttttgc gatctttgcc tctgccgcga ttgctacatt tgggatctta cctgagtatg
     2341 tagtaaaatc cacagaaaac tttgtcagca atatgggctt tttagacttt tatattgctg
     2401 ccttgattac tggtagcatc cttggtatga accgtaatct attgatgaaa gcttctgttc
     2461 gttttattcc cgttgcactt atttcaatgg tcgtctcctt ttttgccgta ggactcgtag
     2521 gtatgcttat cggaaatggt tttgcaaatt ccgttttata tatctcattg cccgcaatgg
     2581 ctggtggtgt tggagccgga gctgtacctt tatcaacgat ttatgcaaat gttttaggta
     2641 cggacgcttc ttctatcatt tcccgcctga ttcctgcgac agcaatgaca aatgtcctag
     2701 ctatcattgg tgcagcgtta gttgctcgtg cgggacaatc aatgccaaaa ttcaacggta
     2761 atggtaaatt aatggaaaaa ggcgaccttg gcgatggaaa acctagaaat gtaaaacctt
     2821 ccattccaca attaggtgtc ggtttgatgg tatcattgac tttcttcatc ttaggacaaa
     2881 tctgtaacta ttttgttcct aaagtccatg cttacgcatt catgatcatt atcgttgtta
     2941 tctgtaaaat cgcaaaccta ttaccagaat attacgaaga tgcagctatc atgttcaaca
     3001 acttgattgt caaaaacttg acagcagctg ttcttgccgg tatcggtatt gcgttattga
     3061 atctaaatgt attggcttct gctttgacat ggcaatttgt tgtcttatgt ttgacaagtg
     3121 ttatcgcgat ttcagtagtt tcaggatttg tcggtcgttt gtttggttta tatccaatcg
     3181 aatcaactat tactgctggc ttatgcaaca actcgatggg tggtacagga aatgtagctg
     3241 tcttatctgc agctaatcgg atggaactta ttgcttttgc tcaaatgggc aatcggcttg
     3301 gtggtgccat cgttttgatc atctcaggtt tcttgatgca attactttct tagtcaaaaa
     3361 aaatacctga tcatcaagta tcggcttgat gaccaggtat tttttgataa aaatttacag
     3421 gattttcaaa aatctttttt gcattttatc ggaatgataa ccgatgcgtt cataaaatcg
     3481 gtgtgcttct actctgtatt ctgcagaatt aagtcttatt gctgatattc ctcgtctttt
     3541 cgcttcttct acgccagtca tcaaggcctt tccgattcct cttttttcag catgtttaga
     3601 cacagcaagt gccataatat tgaacatcgg atcgctgaaa atcgattcat aggactccgc
     3661 ttgtacatag ccagctgctt ttttagaagt aggatcttca tagaccaaga aaaaattttt
     3721 ttctggctcc ttcaacagtt tcttcatttg tctcaccgta acggttaatg gtacatcata
     3781 tcctaattgt tccgcattga tttctcgtag tgcttctgca tctcctaaac gcatttcccg
     3841 caacatccaa atcaccagcc aatttttatt tttttaaatg aattttttta tcacagtata
     3901 ctcctttttt cacttaaaaa aagacttttc agtgattttg acttgcttga atccagatcc
     3961 ttctaatgtt tgcaagatga cgaaagcatt gtaaagattg atcaaaagaa ccacgatgac
     4021 aatcgcttga aaaataaagg tcactttttt tggagacaaa accctgctaa atcttgctcc
     4081 ccacaaacct ccaataacag cagcggggat aacataaaac aacatagata aatcaaagcg
     4141 cataaagcta cttgttaaag caatcgttac caattttgcc agttgagaaa agaaaatcgt
     4201 agatagagaa tatagtgttg cttcttttat tggcaatgca aacatcagca tcaacaaaga
     4261 aacattgact ggtccaccac caatacctaa aaaactagct aaaaagccca gaaccccccc
     4321 acatataagg taccaagtcc atgacgtcaa atgaaatttt ggctgatgat gcttggtgta
     4381 gaagaacgca aaaaccaagg tcaataccgt caaaaaaatt tggatcagct gcacatgctt
     4441 ctcgttttca aataactgta aaaaaacttc gaatacaatg ttgccgacta ctcctccaac
     4501 aacagctcca ctagataccc aaccgacaat ctgccaattc agtgatttcc cgcttgatac
     4561 ttgtcgcaca gtcgaaacaa tggacatcgt gaataccgca actgttgagt aaaaagaaat
     4621 ccctgcaaca gaatgggcgc cgataagatc aagaatcggt ttgatcaaca cgcctccacc
     4681 catcccggaa atagcgccaa ctgtgttcgc cagaacgatc accacaaaat aaatcagacc
     4741 aatcatcttg tatttccttt ctcttgttta tatcttttag cgattgttac tcttttcttt
     4801 tattatacag taaaagaaac aaacgaggct tcgaaagctt ttctactttt taaggaaatt
     4861 tagtgctaaa cgaaaaaacc gggctctact tttcagagag tccagctttt cttacacctt
     4921 atcgattctt ttgttctatt cttcttccgc catgaatgta ttgaatactt cttcgatcat
     4981 atcccattct gcgtctgttt cgatttgttc taactcgcct tctgttccat cttcgttttc
     5041 gatgtatgca taagcttgta attctacatc ttcatcttct gaaacaccag ctggatataa
     5101 aagaacatag ttacgtccaa attcttcttg tccgtcaact gttagcaaga tttcgtataa
     5161 tgtttcattt ccttggtcat ccaccaatgt gatgtgttcg tgtccttcgt gttcgtggga
     5221 atggttatgt tctgtcataa gattacctct tttcttttta ttattaaaat aattgcttac
     5281 ctgagccgtc taaataattt tgtaaaatca tcacagctgc taatttatcg atgacttttt
     5341 ttcgtttcgc tcttgaagta tttgcctgct ctactagcat acgttctgcc tgaacagtgg
     5401 ttagtcgttc atcttgataa tcaaccggca aggagaatag ttctttgatc ttctctccat
     5461 atgacatgga agcttctgcc cttggtccga tggaattgtt catattctta ggtaatccaa
     5521 ctacaaaacg gtctacttcg tactgcgcca ctaattcctt caaccgatca aaaccaaact
     5581 cttcttctgc ctcattgatt cgaatgattt ctactccttg agctgtccag ccaaagggat
     5641 cgctcacagc aacgcctact gtcttagaac cgacatccaa gcccattact ctcataaatt
     5701 cactccatga tttgagaggt agtctttgac aattacttcc atgatttcat cgcgttcgtg
     5761 acggcgaatc aaatttcgtg catcacgata acgaggaatg taggccgggt ctccagaaag
     5821 caagtagccg acaatctgat tgattggatt gtagcctttt tcttccaaag cccgataaac
     5881 aatcgctaat gtttcgctca cttctttttt gcgactatcg tcaaaaccaa aacgtacggt
     5941 ttcatctgta aaacccatga ttctacacct ctttcccgca aggtaattcc agcttacctt
     6001 ctacaccctt attttactcg aagaaaggga aaactacaaa caaatattcc aaacttctga
     6061 ataaattaag aaacacgatt tgtctgattt ttcctttttt ctgtggcttt ttcaaaagcc
     6121 ctctttccat aaagtatacg ctatatttct ttgaaagtat gtttttacac aattttttca
     6181 taaagttcat aaaaaattcg aattgctgct actaattttt cgttttcgtt gcttgccctg
     6241 tctcataatt gatggtgtag ccatcttgaa cattgtagat aaagacattg aattcaattt
     6301 ttttgtcttc aatgctttct gcttccaact gcacacctct tgctaccagt tcatttccct
     6361 cgaaatgagg agtgacacga tagcgtacat gatgatttgt ttccttgata tatgccgcaa
     6421 tatcattttc gtgggcaagc atgtacggag cattcaacga acgtgtccct gtcattaagt
     6481 ttttaatgtt attattttga ccagtcaact ggaaaccaat caaatggctg cggttgtata
     6541 accattgtcc gtcacttaat ttcttttgtt tccaacctgt cggatcaata tacaaaggtt
     6601 ctctcttttc agtaggaaac aagtcttttc ccaacatcgc attggcttgt cctactctgt
     6661 tcaatttgtc tatatttgaa tagctttccc atgtcccttt ggaaagacta agatcctctt
     6721 ttgtaaactc cggctgattc ccattgattt ctatttcttg atgttttcca tcatattctg
     6781 gcacatccgc tacttgagaa gcttgcggtg tggaatcaaa aatggttgta atttgttgga
     6841 agatatctga atctttttgt gtggtggaaa taccgagtgc ccctgcaatc acagcagcga
     6901 cgatccccac gatcgccttg gttgtttttt tgctcatttc tttactcctt tactaacagt
     6961 tccctaaatc ttaacatatg ttcccctata aataaatact ggaaagaaat agaaacagta
     7021 aaaaaataaa accagttttt agacggctta agaatacaaa aaaagagacg gattcatcgt
     7081 ctctactcaa tcacaaaaca ctatttacaa ggtatttatt atcattcaaa aaatttttct
     7141 taatactcaa aactaaacgg cttctgtacg acctcttggt aaacagtgtt caaaagcttg
     7201 catctgcggt aataagtcca accaagtcaa aaacataaga agcttttttg cttgactatt
     7261 cttattactt gatgcagggc agctttttca cagcctcttt taagcgggtg acgggaatcg
     7321 aacccgcgac atcagcttgg gaagctggga ttttaccact aaactacacc cgcgatacaa
     7381 aaacagtata cgcctctttc actccttcct caagtttttt tattctttac gcttccgata
     7441 tgttttgtag taaaataaaa ctaatcaatc aattattgga gaagatgcta tgacgggaaa
     7501 agaattagat ctgttgctgg acacttgttt actcgctggg aaaatcatga tggaaagcaa
     7561 tgcggagatg tatcgggtag aagatacgat gagtcgaatt gctttagctt ctggaaattt
     7621 ccgtttggtc agctatgtca ctcaaaccgg tctctttatt ggtcttgatc gtacctcgac
     7681 catccgaatg gaacaaatta ccaaccgttc gattaattta gaaaaagtag taaaagtaaa
     7741 tgatctttca cgtaaatatg ttgcttcaga gctaacatta gaagaacttt actgcgaact
     7801 gcaagcaatc gaccgagacc gttctttctt tcctgtctgg ttgcaaatcg ttagcgcggc
     7861 agtgatcagt ggaacaatta tggtgttatt tggcggaaag atgaccgatt tacctgtgac
     7921 tttagtcatt ggaggattgg gatacgcagc ttatctatat agtttgaaat tttttagaat
     7981 caaattttta tcggaatttt tatcttcttt attgattggc atagccgcta tctacagcgt
     8041 acgttttggc ttaggaagca atcaggatct aatcattatc ggatgtgtga tgcctttagt
     8101 tcctggagtt caaattacga acgctatccg tgatttgcta gctggacatt atgtctcagg
     8161 agtttctcgc ggaacagaag cgatgatgac tgctacgatg atcggttttg cgattgcttt
     8221 tattttccag cttttttatt aggaaaggaa cacaagtatg gggacgatat ttattcagtt
     8281 ttcttttagt tttttagcga ctgcggcatt tgccgttatt acaaatgtac ctaggcgttc
     8341 attgatttgt tgtggtcttt ctggtgcttt tggctggatg atctactgga tctgtgttca
     8401 aataggcgga tctgctgctt ttggttcatt gcttggttct ttaggagtag cattcatcag
     8461 cgatcttttc tctaaacgtt tgaaaatgcc cgtaacgatt ttcaatattc ccgggatggt
     8521 tcctctagtc cctggtggtt tagcttatca agcggttcga aatctcgtta ctgaatccta
     8581 tcgagaagcg gctcattatg cggtccaagc aattatgatt gctggagcaa tcgctttagg
     8641 tcttgtatta tcagaagtct ttaaccataa catccgtaat ttcaaagtaa agcgtgacgc
     8701 aatcatgatg aaacgaaaaa aacggctttt taaataaacg aagtgtaaca aagaaaaggt
     8761 tgtgaaagag acgttcagcc ttgagcgatg acaaaatatc tcacaaacat tgcgacaagt
     8821 aaccgcagga gcaataagaa gtaattatga gtattaaaaa aagttttgta aaaatagctt
     8881 ctcacatttt tacataaaat tgacttaata ctgagaaact gacttttgaa caccctctat
     8941 ctgtaaaaaa ggggctgcga catgattttt gtcacggccc ctcttcttta ttcaaatttt
     9001 ttccaaaacg ttcgttgata ataaacgatc catagagcgg aaagtattag aactaaaccg
     9061 atcacaggaa tattcactaa ccaaaatgga taaaacaaag ccaacattcc gtataagacg
     9121 ataagaataa tactgatgat caatgaaccc atcatagttg cgactaaacc caaacttcct
     9181 gaacctctgt taaataattg gttaatattg gtccagttca gcagcagcaa ccgataatct
     9241 ctagcgaaat aacgtagtga caataagtag cagccgaata aagaaccaaa tagcaagcta
     9301 gggataaaaa acaaaggcag ctgaaaagac agtccgctta ataatgcgat cccaccagtt
     9361 aaaaaactct gcaatatcca tccgaatctg aacttttctt ttaaatattg gttcatagag
     9421 attggcaaag aacggataaa cagaaaattt tcttgatcca aagaaataag attgctgata
     9481 aaagaagtct gattaactgt taagaaagcc aatgcgatcc ctaccaggaa aacaacaccg
     9541 attaacttat tatctaaatc agttaatttt atttcgcctc ctagggcaaa agcaagaata
     9601 aaaatgattg gagttaacaa ggaagaagaa agaacttgca taatcaaatt aggttctttt
     9661 actaattgag cattgtaact aaataaaagc tgatgcacat tttggttctt tttatgggtt
     9721 ctttttattt tgaactcact gtttgaatca gtcagttgct ctgtaagctt tggtactatc
     9781 agctgtttta cagcaaggaa aaatcccaga gccgtgatag ctagtattcc ccaacccaat
     9841 aaaccttgtt gagaaagtgg ctgactggca gcatcataga atggcaataa tatcgaaatc
     9901 ggatgccgat ctgttaactc attttcaata gtccccgttt gatgattcat ccacatgatt
     9961 ccagcaaatg cgatcagcat cgagctgcca agcaagatac tagaaactgt ttttctatgt
    10021 tttttaaaca ctgctgttcg agccaaacca aaaacaatca aactagccag acaaaaaaga
    10081 ataatcaaaa atagagaaaa caaaaggatt gagataatga tagtaagcaa aatccctaga
    10141 tcagctcgcc atccggttaa aataaacatg actagaagcg gaaaaacaaa aggaatgatg
    10201 gtcaaagcaa ctaccaaaat ctttgctgaa aaaacctgtt cttgtccaaa aggcagaggc
    10261 aaaaatactt gcaggtcatt tccttcaaaa aagatattat aaatgactga tatactttga
    10321 gttaaaccta acataccaaa aagtgccacg taataagtaa agaaacctgg caatttaaca
    10381 aagttcatag caaacatagc aaatccgtaa atcagtaaaa aaatcagccc tgaaaaaaga
    10441 ttttgagaca aaagatagat agttaatcgc tttccctttt ttcctttctc tcttgcttta
    10501 ttcgtgagct gtggattaac atataaaaga ttaactcgaa ttaattctaa taattgtcgc
    10561 ttatacatac ggtccatctc ctgtcgcttg ccttccagcc attttcaaat aaatcttttc
    10621 tagcgtttca tcaggtgagc cattcaataa ttcactaact gccccctgat aaatcaattc
    10681 acctttcttc aaaatagcca gtttatcgca taactgttgt gcggtatcca atacatgtgt
    10741 agaaaaaatg actgtttttc cttttgcggc atgagccttc atcatttctt tcaaatcaaa
    10801 tgctgcttga ggatcaagtc cttgcaaagg ttcatccaat acccaaatat ctggatctgg
    10861 cagcaacgtg ccgatcaaaa tcgttttttg acgcattcca tgtgaaaaac ttgcgattgt
    10921 ttcattttga tgactataca tatcaaaaag cgctgtcaat tctgctaaac gcttttcttt
    10981 tttttgtgtg tctaattcat aggcagctga aatcaagtcc caatattctc cagccgtcaa
    11041 ttgtaaaaaa atatctgggg aatcaggcac ataaccgatt ttttgtttga tactcaatcg
    11101 attttccgtc aatttcattc catctactaa aatcgttccc gatgatggtt caataatact
    11161 aactaatctt ttaatcgtag ttgattttcc ggcaccatta tgtcctaaaa atccaaaaat
    11221 ttccccttgt cttatcgaga gagacaagtc ttttaatgct tgttttttcc cgtaactttt
    11281 acttacattg atgaattcaa tcatttctgt actccttttg tttgttatta ctttttattg
    11341 tacccttcgt tattggtgga gtaaatgtca aaaagagtgc ataacaaaaa aggatagaaa
    11401 cgactaggct gctacttggg ttgttctctt ctacaggaaa acactcttct aacaggtaag
    11461 atatgagtct ttgttttctt taaaatgatt cattttctat cttttcttgc ataaaattct
    11521 ttagtttatc aatacttctc tttcccatct ctagttgttc tccatttgca aatgttacta
    11581 tttcgtttac tctgctaata gatgtaatgt tttcagtatt aatgatataa gcttttaaat
    11641 ctttacataa atactcatat tcgagtgatt ttttatattt tttaattgtg ccgtttacga
    11701 gaatctcttc atctttcaat actaggccta ttttattttt ataacctggc atgctcatta
    11761 gataaaggat ttcatcgtaa tggatatagt gatcgctatt accataacgg acagttgtcc
    11821 accttttttt cgtagcatgt tgaacaggat agttttcttt ttctttcaat aagtaacttt
    11881 ggatgctttt tttatttttt tcataagtga attcttttat caaataacca ctaggcgtaa
    11941 tctttcgatt aataacagtt attgctttat tcggatgaga cgttagataa acaattttac
    12001 acttttcatt cttttctcta agcatttcgc ctagttcgat accgctataa taggcgttca
    12061 aatcgatgtc taggaaaaaa atatctgagg aatagatttc attattttta atgaattcaa
    12121 caaattgtat aacgttcaat ccctgaacga tctcaaattt ccaaggactt aataaaattc
    12181 tggattcttc caaaatttct actagcattt tttcaaaaac caaactatca tccaaaataa
    12241 atatacgcgt taccataaaa agtacctcca ctcgatattt tactatcaaa atcatttcat
    12301 acaacttttc aacatacatg ttaggaataa attgtaattc tcttcacaat cttttccaac
    12361 acctttgaaa ccgatatcaa atactttcag gatgctgctt ctaaaataaa tatcaaacaa
    12421 atgaatacat catgcaaaaa aagccagaca accgacgtcc ttgcgtgtca gctgtctgag
    12481 ctatgtttat ttattttgtt cttttaaaaa gaacgataca catactgatt tttcggagca
    12541 gagactttct cagcgtttgt aacaactaca gatgggattt cacgcttgaa tggttgataa
    12601 tagtctgatt ggatggttcc ttctatttta taccattcat catttttaac cgttactcct
    12661 tccggcatat gcgtcaacaa accaaagact cctgaatctg ccacacaatg gataatgccg
    12721 aatcggaaca agaagatatc tgtattgcta tcgttcggtg tttggtaaac aaatccttca
    12781 tagctgattt ttttgccaat gaattcgcta gggtaattat aaattagctc cataacttct
    12841 aaatagtttt catctgtgat cttgatagtt tgcttatccc catacttttc tttcaactca
    12901 ttcatttggt ctaagtagtc tgatttgttg aaataaatac tggtatccgg ctttaagtat
    12961 tgtgtctgca tctccggatc ccctactgat tctttactta ctgggaaatt aaatcctttg
    13021 gcttctacga tcgtagtgtc gagactaact gttggaaaca acgtccccac gattactggc
    13081 aaagctagca gtacataagc gattccacgt tgataaggtt ttgacaaccc atggtcatga
    13141 tcgtgctcgt gtgccttttc ttctgctttt ccgtttttga cccacaaata cagctgaact
    13201 aaagccaaaa gagcagataa aatcattgaa agaatagcta agtagcgata atggacattg
    13261 atatattgat cgagtttgcc agaaacttgc aagtacatca tcaattcgaa atacccagat
    13321 aaaatcaaaa accgcagcat attttccctc ctaaataaat aatgtgaatc caataacgct
    13381 aagggcaatc agtccgatca gcgataaaat aaagcgtcct gtaaaatatc gtttcatcat
    13441 cagtagattt ttgatatcga ccattgggcc aaagaccaaa aaggcagcta caggtgctgt
    13501 gccgaacaga cttaacaaag aagatcctat aaacgcatct gcttctgagc aaagagacat
    13561 cgtaaaggcc aataacagca tgatgataat ggctaaaatc tttgttgagc cgagcgttag
    13621 cataattcta gttggtaaat aagtctgcat cgcagctgcg attaatccgc caatgatcaa
    13681 ataacgacct gtatcaaaaa attcgtcgat tgaatgtgtc aacacatgcc cagtttgatg
    13741 gatcagctga ttttttggtt cattcttctc actttgttct tcttcatgga catgatgatg
    13801 gtgattttct gctactttag acgtgatttt ttctttcaat acagcgtctt tttgaaaata
    13861 ggcaagccag acaccaatca caagggcaac aaaaaagctg cctatcaccc gccagcttgc
    13921 catctgccaa gaattgccaa atgcgataaa agtggaaaaa atcacgattg gattgatgat
    13981 cggagcagtc agcataaaag caaacgctgt gtgaactggt acgccttttt taacaaattg
    14041 atgaacgatc ggtacgatgc cgcattcaca tgaaggaaag aaaaatccta agatcgaacc
    14101 agtaaaaata gagaagatac gattttcagg aagccatctc ttcacacgtt ctggggtcaa
    14161 aaatacttgt aaggcgcctg agataagaca gcctaataat acgaaaggta atgcttcaat
    14221 aacgatcgat aagaaaatcg tactcatctg caaaaccgaa tttggaataa aagaaaacat
    14281 gagtttcctc ctttttattt ctagttcatt cgctttgcaa atatacgctt ttattcaaaa
    14341 aaaacaagtt gctctgtaaa tttttacaca actcttattt tttaccaaag cacttcaatt
    14401 gactttttct gttattccca ttaaattaag gtctcataca tatcacttct atcataaaag
    14461 ggagaataaa aatgaaacaa accactaact tgactgaagt tcaagacata ctgcaacagt
    14521 catccgttgc cgtcatttat ctttcgatgc ctaattgcag tgtttgtcac gctgttcgtc
    14581 cacgactaga ggaacttctc acacattatg atattccggc acttcatttg gatgcatttg
    14641 aaacaccaga agtagctagt aaatttgaag tgctgactgc gccagttgtc ctgatttttc
    14701 atcaaggaaa agaagtcttt cggcaagcac ggttcatcga ctttaaaaaa atccgttatc
    14761 tactagatga actgacagca gaagatgatt ccctttctta tgaagaaatc ttccgaacaa
    14821 aataatcgtt gtccaaacag aaaaaagcga ttgaacaagt gaaagttttg ccttcatttg
    14881 ttcaatcgct ttttattttt attctgctgt attttcggaa tgcgcatttg cgtcagaatg
    14941 caagaaatag atcaaggttt gcaattcatt cgtcaaatca acattttgga tcaatacatc
    15001 tgacggagca ttcaatcgag cagcggtaaa gttcaagatt cctttgattc ctgcttccgt
    15061 taactgattg actacttctt gtgctctttc agcgggtatc gttaaaattg ctacttcgat
    15121 ttgttggatc ttgatttgtt ctgacatatc ttccattgga taaacgggga taccgtctac
    15181 gatgcgccca acgatttcct cattcacatc aaaagcacaa ctgatacgta tgctattact
    15241 ttgatggaat ttgtatttta gtaaagcact tcccaagttc cctacaccga tcagcgcaac
    15301 atttgtcaat tgatcgtcgt ttaatgtctt tgcaaaaaag tgcataagat cttctacatc
    15361 ataaccatac ccacgttttc ctaattcgcc aaaataagaa aaatctcgac ggatcgttgc
    15421 actatctact tgaacggctt cacttaattc agttgaagac acttttttct ttccagcatt
    15481 atttaaaatc cttaaatagc gataatacaa aggcagtctt ttagctgtcg cctttggaat
    15541 aatatgatct ttcacgaaat gacctccacg tattgtctaa ttacatcttt gatttctcca
    15601 tcatagcagt atttatagga aaaaatcaat tccattgctc agatattgtg aaattttatt
    15661 ctttattcat ttatttatca tttctgcaaa tctcgcagta taatggaatt tatggtagac
    15721 tactaattga aaaatagttt tttatttgag gagaattcac aaagtagaaa agaggattcc
    15781 atgatattat tacaagccaa tcagattgct cgccattttg gtgcagaagt cttatttgaa
    15841 aacatacatt tagaaatcag tacaggcgct cgtgtcgctt tagttggcag aaatggcgct
    15901 ggaaaatcga ctttattaaa gatcattgct ggaattgaag cacctgatga aggaaagatc
    15961 gctaaaaata aaacagcgac tctcggatac ctcgctcagg acacaggact tgattccaat
    16021 gaaacagttt ggaacgagat gctgaaagct tttgaacaag ttagacaaat ggaagagcgg
    16081 atgcgcgagc tagagatttt cattagcgaa ggtacgccag acacacctgc ttatagttct
    16141 tatttaaaag aatacgaccg gctgcaacac gatttttcag atcgaaacgg ctatggttat
    16201 gaaaatgaaa ttcgttccgt attgcatggg tttaaattcg attcttcatt ttatgatcag
    16261 aaaatcgata ctttatcagg cggacagcgc acacgtttag ctttagctcg catgcttttg
    16321 caacaccctg acattttgat tctagacgaa ccaacgaacc atttagatat cgagacactt
    16381 tcctggcttg agaattatct gcaaagctat actggtgcat tattgattgt ttcccatgac
    16441 cgttattttt tagataaagt agtcaatgaa gtctatgaat taagcagaag aaaaatgcgc
    16501 cattacaaag gtaactattc gaaatatcta gatttgaaag cagaacagtt agcaagtgaa
    16561 tggaaggctt atgaaaagca gcaaacagaa atccataaat tagaagactt cgttgctcgg
    16621 aaccttgttc gcgcctctac cacaaaacga gcgcaaagcc gcagaaagac attagaaaaa
    16681 atggaccggc tggatcgtcc tcaaggggat gaaaaacaag caaactttct attcagtata
    16741 gaaaagcctt ctggaaatgt agtcttgcaa atcgaagatg ccgctatcgg atatgataat
    16801 gtcaccttat ctgaaccaat caatctagat atccgtcgtc aagaagcgat tgctctagta
    16861 ggtccgaatg gtatcgggaa atcgacgttg ctgaaatcaa tcattcacca gatccctttt
    16921 atccgtggaa aagaaacgct agggacaaat gtcaccatcg gctattacga tcaaggtcaa
    16981 gctgatctgc atacaaacaa gacgatccta gcagaattgt gggatgagca tcctaccact
    17041 ccagaaaaag agatccgaag tgctttaggt gctttcttat tttctggcga agatgtagaa
    17101 aaaccaatcc ctctgctaag tggcggtgaa aaagcacggg ttgctttagc caagttagcg
    17161 atgaacaaag aaaatttttt gattttggat gaaccaacaa accatttaga tattgacaac
    17221 aaagaagtat tagaaaatgc attgatcgat tatgacggca cactgctttt tgtttcccat
    17281 gaccgatatt tcatcaatcg gatcgcgaca aaagtcgtcg aactctctga aaatggcagc
    17341 aaagtctatc taggagacta tgattattat ttagagaaaa agcaggaaga agaagaaatc
    17401 gccgaattgt tggcacaaga tgagccagaa tctgctcctg ctcccacgaa caaatctgat
    17461 tattaccaaa gcaaagaaca gcaaaagctt atccgtagcc ttcaacgaaa aattactcag
    17521 gttgaagaag aaatggcgcg gatcgatgaa tggatcgatc agttggaaca agaaatggtc
    17581 gcgccagaaa acctggaaga tcacgtaaaa ctcaatgagc tgaaccaaga tttagaagct
    17641 gctagacaag atcaagaaac aaaattgacg gaatgggaag aactaagctt ggaattagaa
    17701 gaatatgaaa attaacgaaa aaaccaaaac agaaaccatt catgctgttt tggtttttct
    17761 ttttttattt tatcaaacaa aaattccata tttacctttt tcaccaataa gaagaccaat
    17821 tactagtcat tctcactaaa gcttctaaat aatagtaatc accccaaata caaggtgtat
    17881 ttaccccatt atttttgggc ttattataaa cagactgtgt taaaaagcca tcttcttctt
    17941 ccgttgtagc atatctttct ttcaattgtc gcataatttt ccaaacagca gactggtata
    18001 agttcttttc tgttttgtct aatagacctg attctattaa ttctaataat ccacaaacca
    18061 tgatcaccat actagatgta tctttttctt ctctgctaga atcatcaaag atcaaatccc
    18121 aataacaaat ggtatcttct ggcaaccgat tcataaaata attggctaat attttgctta
    18181 aatcaaaata tttttgttct ttcaaataac gataacttaa tgcaaaaccg taaatccccc
    18241 atgcttggcc tctagcccaa caggaattat cactataacc ttgatgcgta cttccatatc
    18301 ttggttttcc atctttgaca tccatataaa atgtatgata agttgaacca tcttctctta
    18361 ctaaataatc tgctgcattt tgaatatgag cctgagcagc ttttttatat ttttgatttc
    18421 cagtttcttc actcgcccaa tacaataatg gaagattcat gcaacaatcc atgatcattc
    18481 taccttgttg tgaaggatca ctaggatctc cccaagcttg tataactcct gccttctccc
    18541 aaaaacgctg aagtaatgtt tctgcagcat caattgaagc ttccttcatt tttcgatttc
    18601 ccgttatttt ataatctgct acggttgata aagaatacaa aaaaccaaga tcgtgatgat
    18661 tagtgataat ttgacagtca atcctgtgga taaaatctat atctgctttt tcagctgttt
    18721 gttgaaataa aggatcaccc gtcttctcaa ataacaacca attaattcct gtccaaaatc
    18781 cttctgtcca accaatattg tctcttaatg gataacgtcc ttttatagga cactcgcttg
    18841 ggaattgata ctgactgtta ctgatacgtt tgattaacct ctccgtgtgt ctgcgacaac
    18901 gctcgatctc attattccat tctttttcca ttaattcttt ataacattca tttatccatt
    18961 tttctggatg tattatctct tcaaacatca ctttatcaag catttcccca ccagccttta
    19021 gcataatttt agtctttttt tattgttttt attttggata gttagcccgg ttgtcccatc
    19081 aaaatcaatt ttgggacgat tgttccatac ttctaaacta taatcccgat cttgatgagc
    19141 aaccactcct gttccgagcc aatgggttcc ttttccaaat gtaccctcta atccaggaat
    19201 aaaagtgttt tcccatgtca tcaagtttgt attgggcaaa cccataatag ctgtggattt
    19261 tcgtttaata gtatcgtcac ttaaacagat aatacctgaa aagccagctt cactcaccct
    19321 atagttttcc ttgtcttctt ctatgattat tccttctttc tcaggagaac attcaatagc
    19381 aaaccctgtc tcatatagaa catattctgt atctaattct actttgtgta cgcgaatctg
    19441 ccagccttca aaaggaataa gccaagttct gatttttgcc tgtaaagtag gttcccatgt
    19501 agaggcaagt acctctttct tacatacaat gtctcgtaca ttatttcgaa cgatgaactg
    19561 tccataggtt ttgatgctct cattcttaaa actggtcgtg atatatgtgt ccgctcgctg
    19621 aatccctagc attgaatcca ttgccatttc tgctttcaat tgattcgctc gcggtatcga
    19681 aaaaccaaat tgactagaat aagcaaattt taaatatttt tcattggtca atgtatggaa
    19741 atttggccct aattgtcccg cattcaaaaa aaatgtatgt ccattatcat gttgtatgag
    19801 caaattggct tctgaaagaa gtttagttcc ttcacgaata ggcataggca tttctttagc
    19861 cgtccaatac tcatggtctt caggtagcgc caacaataaa aaaatcttat tcagccataa
    19921 tggagataac gtactattat agggttcagt caatgtcaat tgagggtagg tataaccaat
    19981 attcaggata cctttttcat caaatatttc tttttgcatc caccatctta tattccgatt
    20041 gactaacccc ttgatttcac ctaatttaaa aggcaaaaga tcggcccaca acatagctga
    20101 ccaaaagctt gaaactgcaa aacgataaat catgcttcga ccaaaaggca catttgcacc
    20161 atcttccgca aaaaaatgaa tatagtctct agaaaaatca atagctcggt tcttatatat
    20221 ctggctaatg ggcttttctg gttctagtac gctataaatc aaaccataat aatgaaatgc
    20281 aaaaggatta taataatctt ggcgacctct tgaactgtct cgataccagc cattttgaag
    20341 ataacaattt tctatattat caaatgcttc tttcagtgct gattctttaa ctggataacc
    20401 aaatttttgg ataattgttc cgacaattat cttaaaaaat tgccaattac catctgcaca
    20461 ttcatattca aaaatttgcg agaaccaatg aataatctgg cttttttctc ctgtatctaa
    20521 ttttttccat aataattgtt catgatgata taacgctaat aacattgcgg gcatttctac
    20581 catacgctgg tctctttcat gtatttctcc ccaataatcg ggatgggaag gatctgttcc
    20641 agcttttatt cctgatagaa ttaatttcaa ccatcgttca tctaattggt caattgcggg
    20701 ccccgctccc cataaaaccc gagagaatcc ttccattcct gcaattttat ttccatatcc
    20761 taccccttga tgtatataat caatttgtgc gccacttgct cgataaaacg gctggagtgg
    20821 ttgatttatc tttttaaata agtcaaagta atcctgtctg gtccttaata gtggtactgg
    20881 atgtttcatt gtattttctc ctctttttac taccaaatag ctaattccga ctgttctaat
    20941 cgaagtaagc cttcaataaa aaaataatca gaatagatca gtggcacatt ataagtcagt
    21001 tctctatggt atgcttctgc tccgcctcca atgatcccat cttcatccat attccaattt
    21061 gcatagtgct tttctgtctt ttggagtata ttgatagcag cttcatgata catttttgat
    21121 cgtacagagg aaacatatcc tgctaattcc agaagaccgc atgcagcgca tactccagca
    21181 ctggtatcaa tattcgaatc ttttacagca aaatcaatga gaggaatata accagttttt
    21241 tcgattttct gaataaaatt tactgctatc ttttctgcta tagctagata gtacggattt
    21301 tttgtgtaac gataacttaa cgcgaatcca tataaagccc atgcatttcc tctgctccaa
    21361 caagaattct cattgtatcc ttgcccgcca agtaaccgaa tatatttccc tgattctgca
    21421 tcaaattctg cgatatgccc ggttgatcca tctttcctca ctagatactt agctgttgta
    21481 tctgcatgct gccgagcaat tttagagaac ctcggatcac cagtttccct cgaagcccaa
    21541 tacagtaatg gtaaattcat catactatca ataatcatcc aaccaggttt atggtcattc
    21601 catgctacta aatagttccc tgaaatatta tagcgtccag caagtaccgt agctgcatgt
    21661 aaccctagtt gtcgactatg tttgttttga gactgttgat aatgtgcaat agccgatggt
    21721 aagaataaaa aacctacatc atgatgaacg tctgaaaaat ggtacagggc agattctaat
    21781 aattgttctt gttgtattgc tgcctctttg aacttttctc gttttgtctt gtgaaagagc
    21841 tgccataaaa taccactcca aaaaccattg gtccaccagt cgattcctct gtcctttatt
    21901 acgtctgtat attttccgtt gtaagaaata tatggaattt tattccccat tctgtctaat
    21961 tccgcatcta tcttttcaga agctacattc aaaatttttc ttgaccattc cttcgtctgt
    22021 tcattcatgg atatcccgcc attcttttaa tttttatgaa tgtggagttg ctcctagaac
    22081 gaactagatg gttaacattc gttatttttt ttacttattt gcagctccaa tgtcattctc
    22141 cttaaattta gactgcgccc acacataaat caagaccatt gggatcactg aagttgctaa
    22201 aattagcata attgcgccat aattaattgg ctcacctgta ctagaaaccg tcatattttt
    22261 gataattaag ggaaccgtat atttatcttt atctgaaagc atgactaatg gaaatagata
    22321 ttgattccaa cttcccataa agataagtaa accactagta ataatcgtag gtgataaaat
    22381 cggtacagcg attttcgtaa aaatcaccca ctcattggca ccatcgattc tggcagcctc
    22441 catcagtgct gtaggaaatt gactgctata ttgtcgcatc ataaacactg aagttgtact
    22501 ggcaatcgaa gggatgatca cacctgcata agtattcgat aatcctaaac gactcataat
    22561 gtaaaataaa ggaatcaatg tggtaaaaaa aggcaccatc ctagatagca taactgtatt
    22621 gaacaacagt ttattcccca taaaacgata ctttgctaat gcataacccg ccattgtaga
    22681 actggctgta gctaaaactg tactgattac agcaataaca atcgaattcc aaataatcaa
    22741 gggataatta tatctcgcca tgatggcttg ccagtttttt aatagcatat ccccaaactt
    22801 gaaattgatt ccgccactta aaatttcttg attactttgc gttgaagcta caatcatata
    22861 taaatatggc atcaaaaata ttaaggcacc aaacacaata atgacgtacg taaaaattct
    22921 gctttgtatc ttttgtttag tcatttttat cacctccgaa tttaaattga atagccgata
    22981 atataacaga tacaaacacc atcgtccagg caatagcaga ggcttttcca aaatcaacca
    23041 tttcaaaact tgttttatat aaattgactc ctacgaccaa agctgaattt tctggtccat
    23101 tggaagtccc aaagaatata tttgggatat tgaaattacc caagccattg atagtggcta
    23161 aaactgtggc cattaaaatg attggcttta gcatggggat cgttaataaa aagaattgcc
    23221 gaaatttcga tgctccatct atttcagcac tttcgtatat ctctttagaa atcccttgaa
    23281 gaccagctaa aaataaaata gtgttatatc ctacactaag ccaaatcatc gtgatgatca
    23341 ttgatattcg tatccaaaaa ggatttgtta accactgtac accgttaatt cctagcgcat
    23401 tcaaaaatcc attgaataac ccagtcggat tgaaaaaagt catgaatacg gaagctacag
    23461 ccaccgttga tgtaatggtt ggaatataat agacagttct aaaaaatcct tttcctttta
    23521 actgtgctga attcaataaa acagcaaagt aaatagctaa tagcatcgtt attggaattg
    23581 atcctgccat gataatcaaa acattcgtgt aagatttaat aaacaatgga tctcggaaga
    23641 tagctagata attgtcaaat ccaacaaatt caaatgagta gccaattttc ataaaactaa
    23701 aagcaaacga gataatgatg ggaatcaaaa tcgtcacaat aaagaaaata acaaaaggtg
    23761 tgaccaatcc ataagcactt tttttatgag acgtatctgt tgcttttttc ttgctgttct
    23821 ttattgtctt gcttggtaac gaagattgca tcatcgttaa gtcctcctaa tattttttaa
    23881 tcaccagtta attttacgcc gtacttatga gcaaaatttt ctgcttcttt tagatatgaa
    23941 ttttcaaaat cacctgtttg ccaatagtta tatgcagcgg tagtcaaata agacgtagca
    24001 tctgaataag tggctggtaa aacagtattt gatgtatttt cattgatttt attcaatagt
    24061 tcatagtatt tttgtcctcc ttagtagtca aactttttct cagctgcttc tgtttgatag
    24121 gccaatgagt tagatgtagc cacgcccagc tccagtgcgt tggctaagca ttcttcatct
    24181 gtcagcataa atgtaagaaa ttgttgtgcc acttgtggat ttttggcatc tttagggaca
    24241 taaaaacttg atcctcctga tactgcacct tttcctggat tttcttttga aaaaggaatc
    24301 agtggagcca tgcgccattt gtcagatgca tcaggaaaat tcaaagacat attcgtagca
    24361 taccagccgc cagcaacaaa cattgcagat tcttgaaatg ctttctcagc atcttgtgca
    24421 ccgtagaaat gtacaatatc tgagtcgatc atttctttga ttaactttgc agcatgtttc
    24481 gcttctttag tattcagacg gatatttcct tcttcatcaa gcaaagattg attctgctgg
    24541 gctagcatgt tgataaacaa ttcttggtcc ccagattctg gcaaggcaat tccaaaacta
    24601 ccagtttttt cttttaatgc ttttgccacc tggatatatt cttcccaaga actgatttct
    24661 tcaaaatcta cacctatttc agcaaatttt tttggttgat aataacaaag tgctggggta
    24721 aaatcactag cccaaggaat aatcgtttca ttactcgttt gttgacgcaa aatattcaat
    24781 ttttgatcat aaaactgatc gccatatttg tcataaaatc catattcatc agcactataa
    24841 aaagcatctt gaaatttttc cagcacacct gctgctgaag tgtctgccat ggagataata
    24901 tccggcatat cttcgtgtgt taccaatttt ggggtgatca tttgtactgt tgctgttccc
    24961 gaagctacat tcacaatttt taagtcaata tttgctccag ttttgcggtt atagattttt
    25021 gcagcatttt caacatagtt tgtcagtttg ccgtttgcga catatacttc taatgtagtg
    25081 gcttttttta tcattggatc tgcgatgttt gctgttactt cttcgttagt ttttccacat
    25141 gcacttaagc tgaataatag ggtaatgttt agcaaagcta tcaccaattt gtatcttttt
    25201 ttcatgtcta tcccttcttt cttttcaagt tcttatataa aacgctttca cttatgtgta
    25261 ttaacggaat tagtaacaca aatatttata taaaaaaata ttttacttgt cgttttggct
    25321 tttcattttt gttataatag tcattaatta taaatagaaa gctttttata taaaaagaga
    25381 aaggaaagtg gttcttttgt taacaaacaa ccaatcctcc aatcttgtca aaaaaacact
    25441 aacctattcc atagataccc atcttcattt atctgctgct ccctattttc gactactaat
    25501 aaatgaaagc gctaatttat atgctgaatt tgcacataaa tctatagaac tagataatcc
    25561 ttccctttta ttcattgata aacagcaaga agtccaaatc ttttctactc aaaaggaaac
    25621 acaaactttt atcattatcc agttttattt tgatgagcaa ttattagcac atattacggg
    25681 acaatctttt tctatagatc aagaaataac atctatcatt acttttctga aaaatgaaca
    25741 gttcaaaatt gattatctaa aacatagtaa gccagctatt tcctatgatc aggaaatcaa
    25801 ttcttttttc atactatgcc aacagatgag cattcatttg ctttccttat tagttactta
    25861 ttgtctgcaa aaaattcaat tgtcttcctt accaaggcat tatcaacagg aacttgcttt
    25921 attgacaata ccttcaaatg agaaagtcat tcctaaaaaa aagcatattc tttattcaga
    25981 tgaattagtt gatccaatca tacgatattt agaagaacat ctttcagaaa attttttgct
    26041 tgaacaatta gcccaaattt tttttatcag tccagccagc ttaaaaaaac attttagaaa
    26101 agtgaatgga aaaagtgtta ttagctattt taaagaacta aaaatggaaa aagcaaaacg
    26161 tctcgtgcta gaaaatgaat taacctatac agaaattgca gatatattag gatttcattc
    26221 gatccatcat ttttcttcag cttttaaaaa atatacaggg ttatcccctt caaagtatta
    26281 tctatcctta aaatagaaaa aaatttttag gttttatcca caaattattt ctctatattt
    26341 tctgtctatt caaaataaac aataattttc cggcacaatt atttgctgtt ttttaccata
    26401 acatagtacg atcaacgtag aaaaggagat gtttttatga aagttgttgt cattggcggt
    26461 gtagctggcg gtccttcatt tgccactcgt ttccgtcgat tgaatgaagc gcacgaaatc
    26521 attatctatg aacgcggaga aaatatttct tatgcaagtt gtgctttgcc ttattattta
    26581 ggaggtgtga tcactgaccg tgactcgctg atcgaacgta caccagaaat attgaaaaca
    26641 aaaaacaaca tcgatgtctt tactaaacac gaagtaacag caatcgatcc ttctactaag
    26701 cgattaacag ttaaagacct atccacaaat gaagaaataa aaacagatta cgataagttg
    26761 atcatctctt ctggtgctag accagattat ccggatattc ccggagtttt tgaagcagaa
    26821 aacggctttg tcctccgtag tgtgacggat gcggatcgaa tcaaatcgtt ccttgaagaa
    26881 aaaaatccac aacatgtcgt cattcttggt gcaggtgtta tgggtctgga attagctgag
    26941 aatttcaagc atcgcggctt agacgtgact ttaatcgatc aattgccaca agtcgctttc
    27001 ccttatgatc cagaaattgc taatttagtt tatgacaaat tgctgaaaga aggattagcc
    27061 gttcatttag aaacaagagt tactgagatc cgtgataaag gtcgagaaat agtattatca
    27121 gatggctccg tcctttctgc tgatatgcta atttttgctg ttggtgtttc tccgaagaat
    27181 gaagtggtga aagcaaccgg catacaatta tcagatacag gtcagatcat tgttgatgac
    27241 cagttacaaa ccaatctgcc ggacatctat gcgattggcg atattatcga aacgactagt
    27301 gtagtgactg gtcagccgat ccaaagtatg ctttccagtg cggccaatcg tcaaggacat
    27361 atgctggcag atattttaaa tggtacgcct atgcgctatc gcggatatat tggtgcaggt
    27421 gtcgcaaaaa tctttgatca tacagcaagt tatgcgggaa tgacagaaca tgaattaaaa
    27481 gcatcaggca taacaaatta taaaactgtt tttatcactc cctttgacca tgcctatttc
    27541 tatccagaag ctacaagatt aaatctaaag ctgatttttg atgcagatag cggtcgtatt
    27601 ttaggtggac aagcatttgg agaaaaaggt gtcgataaac ggatgggaga actttctgta
    27661 gcaatcaccg gaaacttgac agtctttgat ttgcctgatt tggagttgcc ttactctcca
    27721 ccgtattcta ctacccgtga cccgttgaat atagctggtt atgtcgcaat caatcaaatg
    27781 acgaatatcg tagaaacgat caaagcaagt gatatacccg aaaacgattt gaaagaagcg
    27841 ttctttttag atatacgtga acctaataaa gcaccttctg gcagtatctc ggcaacaaaa
    27901 aatattccaa tgaatgagtt acgagatcga atcaatgaaa tcccaaaaga taaaaaagtt
    27961 tacattactt tcagaagagg attgaatact tatacttctg cccgaatctt ggcaggtttg
    28021 ggtatcaaag cgattttgat tgaagaataa aaaaacgacc gcggtgggta gccgcggtct
    28081 aggagttatt tttacttgag gagtaaaaat gaaaaagtat atagggttgt tggttggtat
    28141 gtatatagaa tagaagataa atgtgaagaa attgtgcatt atttcttcac atttattagg
    28201 ttatagttta agaaagttta aacattgcgc aatttaatta ttttagctgt ttcttttcat
    28261 aaaaaaacat gttgtgactc tgagacaaat catagtccat agtgatgtct ctagagtaac
    28321 tacgcctaat attacgaggc atcatattaa tctatcagca ctagtaccta aactagcatc
    28381 cctttcgaat attttttctt atataataaa gtttgctttc actcctctaa tctcaccaaa
    28441 tcgactggct tgcgttgtgt gatactagga actgattggt ttagaacgac ttttctattg
    28501 taatcatatt tttcgccatc ctcgttgtct tctaatcctt caatgaatga tccctaatgt
    28561 gtgtattaaa taatttaatt tttttgttcc tatttattta
//
LOCUS       DACDLM010000033        26616 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.033, whole genome shotgun sequence.
ACCESSION   DACDLM010000033 DACDLM010000000
VERSION     DACDLM010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26616
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.033"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(107..754)
                     /locus_tag="IV356_001503"
     CDS             complement(107..754)
                     /locus_tag="IV356_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015194.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(933..1652)
                     /locus_tag="IV356_001504"
     CDS             complement(933..1652)
                     /locus_tag="IV356_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP9015195.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(1783..2934)
                     /locus_tag="IV356_001505"
     CDS             complement(1783..2934)
                     /locus_tag="IV356_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HAP9015196.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(3151..3891)
                     /locus_tag="IV356_001506"
     CDS             complement(3151..3891)
                     /locus_tag="IV356_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP9015197.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(3895..4218)
                     /gene="rsfS"
                     /locus_tag="IV356_001507"
     CDS             complement(3895..4218)
                     /gene="rsfS"
                     /locus_tag="IV356_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HAP9015198.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(4275..4868)
                     /locus_tag="IV356_001508"
     CDS             complement(4275..4868)
                     /locus_tag="IV356_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP9015199.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(4852..5499)
                     /locus_tag="IV356_001509"
     CDS             complement(4852..5499)
                     /locus_tag="IV356_001509"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HAP9015200.1"
                     /translation="MNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHLV
                     MAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIELA
                     RGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPGY
                     TTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(5512..5823)
                     /gene="yhbY"
                     /locus_tag="IV356_001510"
     CDS             complement(5512..5823)
                     /gene="yhbY"
                     /locus_tag="IV356_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HAP9015201.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(5839..6948)
                     /gene="yqeH"
                     /locus_tag="IV356_001511"
     CDS             complement(5839..6948)
                     /gene="yqeH"
                     /locus_tag="IV356_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HAP9015202.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(6945..7472)
                     /locus_tag="IV356_001512"
     CDS             complement(6945..7472)
                     /locus_tag="IV356_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HAP9015203.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(7652..8437)
                     /locus_tag="IV356_001513"
     CDS             complement(7652..8437)
                     /locus_tag="IV356_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HAP9015204.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(8430..9299)
                     /locus_tag="IV356_001514"
     CDS             complement(8430..9299)
                     /locus_tag="IV356_001514"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HAP9015205.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(9300..10679)
                     /locus_tag="IV356_001515"
     CDS             complement(9300..10679)
                     /locus_tag="IV356_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HAP9015206.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(10687..11106)
                     /gene="fabZ"
                     /locus_tag="IV356_001516"
     CDS             complement(10687..11106)
                     /gene="fabZ"
                     /locus_tag="IV356_001516"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAP9015207.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(11131..11607)
                     /gene="accB"
                     /locus_tag="IV356_001517"
     CDS             complement(11131..11607)
                     /gene="accB"
                     /locus_tag="IV356_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HAP9015208.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(11610..12845)
                     /gene="fabF"
                     /locus_tag="IV356_001518"
     CDS             complement(11610..12845)
                     /gene="fabF"
                     /locus_tag="IV356_001518"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HAP9015209.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(12864..13601)
                     /gene="fabG"
                     /locus_tag="IV356_001519"
     CDS             complement(12864..13601)
                     /gene="fabG"
                     /locus_tag="IV356_001519"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HAP9015210.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(13613..14530)
                     /gene="fabD"
                     /locus_tag="IV356_001520"
     CDS             complement(13613..14530)
                     /gene="fabD"
                     /locus_tag="IV356_001520"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAP9015211.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(14637..14861)
                     /locus_tag="IV356_001521"
     CDS             complement(14637..14861)
                     /locus_tag="IV356_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAP9015212.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(14914..15876)
                     /locus_tag="IV356_001522"
     CDS             complement(14914..15876)
                     /locus_tag="IV356_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HAP9015213.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(15886..16326)
                     /locus_tag="IV356_001523"
     CDS             complement(15886..16326)
                     /locus_tag="IV356_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP9015214.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            16632..17597
                     /locus_tag="IV356_001524"
     CDS             16632..17597
                     /locus_tag="IV356_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAP9015215.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(17654..17884)
                     /locus_tag="IV356_001525"
     CDS             complement(17654..17884)
                     /locus_tag="IV356_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HAP9015216.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(17970..18857)
                     /locus_tag="IV356_001526"
     CDS             complement(17970..18857)
                     /locus_tag="IV356_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HAP9015217.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(18946..20169)
                     /locus_tag="IV356_001527"
     CDS             complement(18946..20169)
                     /locus_tag="IV356_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAP9015218.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(20186..21265)
                     /locus_tag="IV356_001528"
     CDS             complement(20186..21265)
                     /locus_tag="IV356_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAP9015219.1"
                     /translation="MLYYISEGGRKVKVLLYFESEKMLAKSGIGRALDHQKRALTEVG
                     ISYTLDEKEDYDILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQL
                     SPIVKKYLVGLYQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQ
                     KFREYFKLSPDQKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIR
                     KIVKEDHPENVLFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVR
                     DIPVYNGWLEDSKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEE
                     LKNVYESVLNEKVSSKLKKVNQVKD"
     gene            complement(21396..23123)
                     /gene="ptsP"
                     /locus_tag="IV356_001529"
     CDS             complement(21396..23123)
                     /gene="ptsP"
                     /locus_tag="IV356_001529"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HAP9015220.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDTMEEV
                     VELVHEYVK"
     gene            complement(23123..23389)
                     /locus_tag="IV356_001530"
     CDS             complement(23123..23389)
                     /locus_tag="IV356_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HAP9015221.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            23868..26102
                     /locus_tag="IV356_001531"
     CDS             23868..26102
                     /locus_tag="IV356_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAP9015222.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            26250..26570
                     /locus_tag="IV356_001532"
     CDS             26250..26570
                     /locus_tag="IV356_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAP9015223.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
BASE COUNT         7439 a         5782 c         4596 g         8799 t
ORIGIN      
        1 aaaaagtact gtaagtaaaa agacaactgc tatcattaat gttagcagtt gtctttttat
       61 ttacaataat aattgcagaa aaagtaattc aatcatttaa ggtcatttat tctatatata
      121 aatccaaatc tgtttcagga tattttaatt tgacaagcga aataatcatt ttcagttctt
      181 ccatgttttc tggatattct gggtcaaata ccttgctatg acggccaatc ccgccattgt
      241 cgatcaatcg gtaaattcga ttccattcaa tgaattggtc aattgattgg aaattgctga
      301 ttggatagcc gccacaatcc aaaatctctg atacacgaaa tgctaggtat gcactatcga
      361 tcactttatt ttttttcgtg tctatcttct catttctttc gataagaatt ttttcaggac
      421 gatgtttcaa gctccactct aatagtagaa agaaagcctc catccgatac tcttcttcaa
      481 ataaccgaaa ggctgaatca gaacgacgaa aaagcagcgg aatcagataa ttttgtctat
      541 aaatcagcat tggtgcgcgg tccaccatac actctaaata acggttcaga taccctgtac
      601 cgacatagtt tcctaatcga tagccttcaa cgccgaatct tgcgtatttt tgcgctaatt
      661 ttgaacaatc agttacgttc acagctaact cttctacttt gcggtaaccg cttaagatac
      721 gttcaaaagg ttctaaagtg atttttgctt ccatattctt ccccgtccat cttccacata
      781 cttcatatca tttcacatga tacttatgct ctcatcatac cacaggttga attagaaaag
      841 aaaataaatc acacaaaaaa gcaagacaat ctgttagtga gattgtcttg cttttcgaaa
      901 aagactgaat acttttcgtt aaaactggtt gcttagtctt ctaatgccac attatggaac
      961 acatgctgta catcttctag atcttccagt gcatcaatca ttttttcaaa tgtttcttga
     1021 tcttctggag atagtgttac ctcgttttga gggatcattt ggatctcagc gattgaaaaa
     1081 tcagtgattc ctttttcttt taatgcttct tgtatactat ggaaatccgc tacttcaccg
     1141 taaacgatga tttgtccttc ttcttccatt acatcgcgaa catcgatgtc tttttccatt
     1201 aggtattcaa ggatctcgtc agcgtcttct cctgcaaaag caaagattgc tgtattgtca
     1261 aacatgtaag aaaccgctcc ggaaacaccc atgttcccgc catttttccc aaatgctgcc
     1321 cgtacgtctg ctgctgttcg attcacattg ttcgtcaatg tatcaacaat caccattgag
     1381 ccgcttggtc caaatccttc atagcgcaat tcagagtatg tttcatctcc tgcacctttt
     1441 gctttttcga ttgctcggtc aataatatgt tttggtacat tataagtttt agcgcgatca
     1501 atgacgaaac gtagtttttg gtttgcatgc ggatcaggat cacctgattt tgctgccgcg
     1561 tagatttcaa tcccaaattt tgcataaatc cggctattat tagcatcttt agcagttttc
     1621 tttgctacga tatttgccca tttacgtccc atattttcac ttcgctttct gatttgatag
     1681 tttcataacg caaaaacgtc ctgttccatt atacttgtga atcacgattc tgtgaagctt
     1741 tttttctttc ttccttcatt cttctcattt ttagtcaatt atctatactc ggattgggat
     1801 ttgcccgaaa ttctgttccg gaatattgcc tcccaattga tagatttgat cacttctaac
     1861 taacagttcc gcttcttgtg cctctttttt tccgattcgg gaataaatag aaatctcttt
     1921 tttttctttt aagaatcttc ttccagcatc ggtaaatcca agtagtcgaa gataattttt
     1981 attttgttgg acaggaatct cttgcttttt gatattcagc aagacataac aagataatcg
     2041 ttggatccgt gtccatgtat atctttttgt ttttaccttt gacacaaaat cctcaaaact
     2101 atcagcagtt gcagctgctg ttttcatgcg cgattctatt ccttcggtca tctgatagat
     2161 atctgtcagt tccagcaaag tagaagataa caaccgataa cgcaaatacg gccaataaga
     2221 ttcccaagtc tgcagcgaac aagttgaaag atcttcttct gtctgaggcg gcacaagtcc
     2281 agctattctt tttccttctt ctaacgcatg gcgaatggct gttgcactgg ctatcctctg
     2341 atctgtgatg attttttcat gatagcctgc acttttacgt cggatcggat gtaattccat
     2401 agggtggaca tacttggcat tttcctttgc ataacttaat cccaagatat gatttggcga
     2461 agaaaaatca agcgtaatat cgggatacag actgcgaaaa acctcagtca ttttttgcgg
     2521 ataactatac gtttgatcag acagttcttg aaatgcctct tctatcctat cttgattctc
     2581 ttggacaaag cgtccgaaac tgctgtaatc aaacgaagtc tcttcttctg ttccaaaaca
     2641 caaactgtca cagtccagtg tttgcaagat ttttactgca cctttagcaa aatagtcagc
     2701 tgactgaacc gcccattcga cgggaagctc cactactaaa tccacaccat tttgtaaagc
     2761 ttcattcgcg cgatgccatt tatcgatgat agccggttcg cctctttgca aaaaattccc
     2821 gctcattaca gcaatgacga cctctgctcc tgttattttt cgtgccattt ccacatgata
     2881 gcgatgtcca ttgtgaaaag gattgtactc tacgataatc ccgcagcttt tcatgcgcat
     2941 cctccttcat agttatcgat aaaaaagaaa tagagacaag taaaaaaagg caaaaatcgg
     3001 aaaaaatacc cgaactatat aaactattct cgcaaacaca atacttctgc gacgaaaagc
     3061 tgcactgcaa gagcaatgcc tatatcgttc ggatatataa tttatgttga agatttattc
     3121 ttttcttgtt aactcgagca ggcaaaaccg ctagtctttg tatgctacaa agaaccagcg
     3181 ctttgatttc tctgatgctg cttcgtctgt aaaatcagaa aatgcttcga ctttcgaaaa
     3241 gccgctgttt tccagcattc ttaaataact ttccaatgga taggtacgct cttgatgtag
     3301 ttcatcttca cgaataaatc gaccagaccc ttcttgttct tcaacgaaaa aggtaagaaa
     3361 atgttcgatg ctgtgtttct cgcttcctgg ataactatcc cacaaaaaag caaaattatc
     3421 cccttgataa tgatagctat attctggaaa aacctcatct acttgatagg tggagtgtac
     3481 gtcaaataaa aatcggccat tttcttctaa cgcttgatag acttcatcaa acacttgctg
     3541 tacctcttgt ctatttttca tatagcacag cgaatcagaa aaacaggtaa ttgcctgata
     3601 ttgtccgatt tctgataaat cgagcatatt gccttccaca aattggatcg atgcgtcttc
     3661 ttcatatgct cgctggctgg caatcatcaa catctcttct gaaaggtcta accctgtcac
     3721 tttatatcca tcttttgcaa aggcaaccgc taatgctcca gtaccgcatg ccagttccaa
     3781 aatatttttt gtgtcttctt gtaaatgacg tttcgaaaaa gctaaccatt gctgataaag
     3841 tgtttcgtcc atcacttcat cgtaaatgaa agcaaatgtt tcataagcca tatgttaatc
     3901 caaccattca ctaagatcga ctagcggagc atctgaccat agtttttcca gattatagaa
     3961 atttcgttct ggcgcatgga aaacatgtac gatcacatct ccaagatcga tcaataccca
     4021 ttttccgcct tcttttcctt caatacgttt tacttcatat ttgttttctt cttctttatc
     4081 aatgatttct tctgtaattg cgttgatttg acgttcgcta tttgctgaac agatcatgaa
     4141 ataatctgcc aacaaggaaa catttcgaac gtctaaagcg ataatgtctt ctgcccgttt
     4201 tgaatctgct gcttcaatcg caatttttaa ttgttcttta ctatctatga tgatttcctc
     4261 ctaatatgag cagcttattt ttttgctacc cagtaattat atgtttcgat tgtttttgga
     4321 taaatctgtt gttcttgcgc aagcaaatgg gccaatgtat gttttgtttc aaatgctaca
     4381 gcttcgtcta gatcagccca tgcaatggct cgtgcatctt gtaccccagg aaaatctcga
     4441 cctggttcaa tatagtctgc tacataaatg attttgtcaa ggagactcat cttagcagcc
     4501 ccagtcgtat gcacccggat tgcatgaaga atctctgcat cggtgattcc taattcccgc
     4561 tctacaaacg aagcgccaac aagaccatgc cagattgcat tattataatt caataactcc
     4621 ggatcaaaac cgtctcttac gattaccatt ttgaactcct catctggtcg ttcttttgca
     4681 taatcatgtg tcaatgcagc aatactagct ttttcaggag aagcaccgta ttttttggca
     4741 agagccacgg ctgtttcttc tactccaagc acatgcttga agcgttgttc gctcattctc
     4801 atctgtattt tttgcatcag gttttctcta gaataagcag tatattcatt actatagtcc
     4861 atattcatac aacccttcat tttgaatata atcaattact ttatctggaa caaggtagcg
     4921 gatagaacag ccttctttga tcttttgacg tattttcgtg gaactgatgt cgatctcagg
     4981 tacatctacc caaattacag gatatggagt atccgttgtg tatcctggtc gacgtatacc
     5041 cacaaagttg accatagaag tcagctcatc gattttatac cattttggca aatattctac
     5101 catatcccca ccgataataa agtaataatc tgtatccgga ttgttttgcg tcaattcctt
     5161 catagtatca taggtgtaac ttttcccacc acgagctaat tcaatcgttt caatctgcaa
     5221 aaaaggattg tcttccaccg ctaattccaa catgttgagt cgatgttttg catcaatcgt
     5281 ctgtttctca tcaacatgag gtggctgata agaaggcatc aaaaatacgc ggtcaagacc
     5341 taaattccgg ccagcttgtt cagccatcac taaatgtgca aggtgaacgg gattgaatgt
     5401 tccgcccaag atccctactt gctttttctt ctctaagaat tgaggcattt cttcaggaaa
     5461 taattgtgaa cgaacaaatg tcttagcttg cgtattcatc atggtcactc cttatattgc
     5521 ttttacttct tttgatagcc tttgatactt ttcttttgtg gaaggtttgt ataatacaat
     5581 aacacgtcca atgatttgga cgatttcgca atctatttct ttttctaata cttgagctgc
     5641 ttcttctgca atctcatctg tattttgaag taacgatact ttgatcagtt ctcttttttc
     5701 taaagcttct tcaatttgaa cgatcattgc tgaattgatc ccaccttttc cgatttgaaa
     5761 aatcggctga agatgatgcg ctttgctacg taaaaaacgc ttttgttttc ctcttaaact
     5821 cataattttc cttcttcctt aaatcaatgc tttgcgtttc aatacatcta caccctttgg
     5881 cgcccagccc gcaattacta ctggcgctgt tacagtgatc cagcctagac cggcaaaaac
     5941 gatgtctgtt ttttctttca cagaaaactc aaaacgaaca agctccggaa atgcctcgac
     6001 ttcatcagga cgaggaggct gtaataatcc acctacatgt ttttgataaa attcgtctgc
     6061 tttttccagt ttcgttcgat gaatatttac atcatttgac acataagcaa taaatgaagc
     6121 acgattgccg ctgataaaat caaatcttgc aagtccgccc aagaaaagtg tttgcccttc
     6181 attcagctga taaactttag gtttgatttc ttttaacggt gcaatgatcc gcaaatcttt
     6241 tttacctaag tagtgcgcca tttgatggcg atggataatt cccggtgtat caatcaaaaa
     6301 atgcccgtca tctaaaggaa tctcgatttt atccaaggtc gttcctggaa actgcgaagt
     6361 tgtgattaca tcttgtactc ccgctgtatt tttgatgatt tgattgataa gcgtcgattt
     6421 tccgacattt gttactccga cgatatagac atcccgtcca tcgcggtatt cttcgatttt
     6481 ttctaatagt tccgtcatct catgagattt cttagcacta gttaataata catctactgg
     6541 acgaattcct gcttcgtaag cacgttcctt catccattgt gttaatttag tttttttcaa
     6601 tgatttaggt aatatatcca ctttgttccc aactaaaagt actggattgt caccgacaaa
     6661 acggtgtagt cctgggatta gtgaaccatt gaagtcaaaa atatccacca cattgacgat
     6721 caatgcatct ttttgcccta attcattcag taagcgcaaa aagtcgtcat ccgtcaatga
     6781 gacatcttgg gtctcattat aatggcgtaa tctgaaacaa cgctgacaat agacttcccc
     6841 ggaagctaaa cctttttcca aagccgtttg cggcgtgtat cctaattcac cgggtttgtt
     6901 tgtttgtata acggcaccac agccgataca ttgtaattct tctgtcattc gattccacct
     6961 cgccagccca tatcagggtg ttttgctaat agataggcca taattctttt ttcccaaaaa
     7021 cgattaaatt gtgtcttcca actatctgtt gcgataatgg gttttacaag gatgctacgt
     7081 atccctgcac gattggctcc acgtatatca gtcataatct gatcgcctac cattactatc
     7141 tcatcatctg ctaaatccaa ttgtttcttt gctatgttga tccctcttgc taaaggtttc
     7201 attgctcgtg caacatacaa aagatcaaat ttttcaatcg ctcgcgcgac acgttttgaa
     7261 ttattgtttg aaacaacaac aacagggatt cctgcatttt tcatttctaa aatccaagta
     7321 agcaactctt ctgttccatc tggattattc catgcaatca acgtattgtc taaatcggtc
     7381 aatactgctt tgatgcctag attctttaat tgggcaggtg taatctgata gatggcttct
     7441 accatccatg ttggtttgta atttgaaaac atgctgtctc ctcatctgca aaaaatgaag
     7501 gagcacataa agtactcctc aaccccgtat tatactgcat atcagcaaaa aaaactacct
     7561 ctatactcgt tcgtctttca gaaaaagcat ttctttacaa aatgaccaaa aataaagatt
     7621 gatcacagaa aaatttagaa acaaaaaaca actaatattg gcggaacctc ttgtatcgtt
     7681 tttccagtaa tttatgctga tctaatcgaa caagttccgt caatctttca atcaacgctt
     7741 ttttcataat gtgtgcgact ttatatcgtg gcaactgctc gccgttgaac gtttcaggaa
     7801 taactcgatc aacgattcct aactcgcgta gttctggcgc agtaattttc atcaactcag
     7861 ctgcttctgc ggcgcgacta ccgtctttcc acaaaatcga cgcaaatcct tctggagaaa
     7921 gcacagcata aatcgtttct tccagcatcc agacttcatc cgctaaacct agagcaaggg
     7981 caccgccact tccaccttca ccaatgatga tggcgatgat cggtaccttt aaatcagaca
     8041 tttcgagcag atttctggca atagcctctc cttcgccgcg ctcttctgct cctacaccgc
     8101 aatatgcacc tgctgtattg atcaaggtaa tcaccggtct attgaacttt tccgcttgtt
     8161 tcatcagtcg taaagctttt cgatagcctt caggatgggg agaaccaaaa tttctgcgga
     8221 tattttcctg cagatcccgt cctttttgaa taccgatcac tgttaccggt ttgccatcta
     8281 atcgagcgat tccaccaaca atcgcttcgt catctgcaaa taaacgatca ccatggcatt
     8341 cctcgaaaga atcgaagatc tcttcaaaaa aatccaagct tgtccatcgt tctttagctc
     8401 ttgctaactg aacgacatca tgtgctgtct tatccacgat ctatccatcc tttctgtgta
     8461 tgcaattcaa gaagcgtatg gattttctgt ttcaattcca tgcggggaac aatctgatcg
     8521 acaaaaccat gagataataa gaattcagcc ttttggaaat cttctggaag ttcctgcttg
     8581 atcgtctgtt cgatgacgcg tcttccagca aaaccgatca agctttgggg ttctgctaga
     8641 ataatatcgc cttccattgc aaaactggca gttactcctc cggtcgtcgg gtccgttaaa
     8701 acagttagat aaaaaagacc ttcattgcta tgccgtttga cagcagcaga gatttttgcc
     8761 atctgcatta gagaaaagat tccttcttgc atccgtgcgc cacctgaagc tgtgaacaag
     8821 acgactggaa gactttcctt tgttgctcgt tcgaataatc tggtgatctt ttctccgaca
     8881 atcgttccca tacttcccat gataaaatta ggatccatca ctccaataat gaagggaatc
     8941 ccctgaatgg ttgctttacc agtgaggact gcttcatgaa gtcctgtttt atcttgcatt
     9001 tttttaattt tttccgtata ttcgggaaat gctagcggat ctttggttac aagatccgta
     9061 tcccattctt caaaactttt ttcatcaata atcaaagcta gacgctgcca tgcaccgatt
     9121 cgaaaagcgt atccgcaatg agggcatact ttttcttcac cgatgtcttt cgtataaagg
     9181 atatgtttgc aatttggaca ctttgcccac atgttatcag gaacagatgg cgagttagca
     9241 ggtttgctct ctctattagg attgatccga atatatttct ttttcttaaa cagagccatc
     9301 tatgcgcctc ctatctccgt ttctggtgtc caattcggta aaaattcttc ttgtaaaaat
     9361 gctgtgctgt aatcacctgc tatgactgca ggatgactaa tcaaatccat ctgaaattct
     9421 gcgttcgtga tgattccttc tgtgataaat tcacttaagg ctcgctgcat cttcattaat
     9481 gcttcaaaac gcgtatttcc atggacgatt atttttgcaa tcattgaatc ataatatggc
     9541 gggatcgtat atcccgggta aactgcactg tctactcgca gtcccatccc acctgctgga
     9601 agcagtaagt tttggatctt ccctggagaa ggagcaaaat ggaaagcagg attttctgca
     9661 ttaatccggc attcgattgc gtgtccttgg aatactactt cttcttgaca cacattcaaa
     9721 ggctcaccgg ctgctatctc cacctgtttt tttactaaat cgattcctgt gaccatttct
     9781 gttactggat gttccacttg gattcgagta ttcatttcca tgaaataaaa atcgccttct
     9841 tcatccatca gaaactcgat cgttccggca ttttcataat tgactgcttt agctgctcga
     9901 acagcagcgt ctcctagtgc ttctcttttt gtttgtgaga tcactacaga aggagattct
     9961 tccagtactt tttgattgtt gcgttgtaaa gaacaatctc gctcgcctaa atgaatgaca
    10021 tgaccaaatc gatcacctaa gatctgaact tctatatggc gagcaggata aatgattttt
    10081 tccaaataca tatcatcatt tccaaatgcc gctgctgctt cttgctgagc tgaagaaaaa
    10141 tgctgtggga gctcttcttt tgattgaact ttccgaatgc ctttcccgcc accacctgca
    10201 gctgctttca gcatcactgg ataaccaatt ctgtctgcta tttccaatgc ttcttctact
    10261 gtagataata caccagtact tcctggaatg actgggacat ttgcttcttg catcaattga
    10321 cgcgcattga tcttatttcc cattgcatcg atcgttgcac ttttaggacc aataaatgtg
    10381 atattgcact cttcacacat ggaggcaaat cggctatttt cagataaaaa accaaatcct
    10441 ggatgaattg cttcggcttt tgtcacgatt gcagcgctca gtacttcctg aacattcaga
    10501 tatgaatcaa cggcttttgc cgggccaatg cagattgctt catctgctaa ctgtgtatga
    10561 agtgcttcgg catctgcttc tgaatatatc gctacggttt ggatccctag ttcgcggcat
    10621 gcacgaatga tacgtacagc gatttcaccg cggttagcta tcaatacttt agaaaacata
    10681 tttcacctat ccaatcataa aggttaattc cgcttcggct acttttttac cgtctacttt
    10741 agcgattcct ttgcctattc cggctgaagc tttcactttc aatatctcaa cttcaaggta
    10801 taaggtatct cccggtgtaa ctttcttacg gaattttgct ttgtccaatc cgccgaaata
    10861 agccgtcttt cccttgaatt gttcaagaga aagtaatgca actgctcctg cttgagccat
    10921 tgcttcaaca atcaataccc ctggcataac aggttcttct ggaaaatgtc cttgaaaaaa
    10981 gggctcattg atcgttacat ttttcttagc aacgatccgt tctccttcaa ccatttcttc
    11041 cactcgatca atcaaaagca ttggataacg atgtggaatg atttctttta tttcttgtat
    11101 gttcattgtt ttccctcttt cctgctttgc ttatttttgc tgaatcctaa agagtggctg
    11161 tccatattcg acaactgact cgttttctac aaggatttct gtgatcactc cgtcggcctc
    11221 actagttatc tcattcatca gtttcatcgc ttcaataatg cagataactt ctcctttggc
    11281 aacttgatca cctacttttt tgaaagctgg tttgtcgggc gctggttgca gataaacgat
    11341 tcccacgatt ggcgaaacaa cctcgattcc atcaaatact gccgattctt tttctttcat
    11401 tatttctgga gcagttgttg cttgttcagg tatgacattg actggctccg aaactggcaa
    11461 cgtttcgttt gtttgaacca tattcatgcc tcgacttgtt ttatttttat tcatatacaa
    11521 ttcaaattga ccttcacgca aatcgaattc cgttagcgag gattgatcaa attgactgac
    11581 taattctctg atttcattga tatccaaaat tattcctccc agcgtttcat gcacagaacc
    11641 gcattatgtc cgccaaaccc taatgaatta ctcattgcat aagtaaaact tgcaggtttg
    11701 ctttcgtttt tgacaactgt caagtcaatc tcaggatctt gtttttctac attgatcgta
    11761 ggtgggataa attgatgttc taatgccagc aaagttgcca aggcttcgat cccgccggct
    11821 gctcccaata aatgtccagt catcgatttc gtgctgctga cgtaagtatc tctgaaattt
    11881 tcacctaatg cgatttggat tgcttttgct tctgcctggt cattggctgg tgtacttgtt
    11941 ccgtgagcat tgatatatcc gacttgttcc ggctgtacac cagcttcttc catcgcaagc
    12001 ttcattgctt tagatgcacc agaaccatct ggagtaggag ctgtcatatg gtaagcgtca
    12061 cagtttgcac cgtatccaac gatttctcca tagattttgg caccgcgagc ttgtgcatgt
    12121 tctaaagatt caagaactag aacgcctgct ccttcaccca tcacaaaacc attccgattt
    12181 tcgtcaaacg gaatcgaacc acgattagga tcagttgatt ctgagagtgc tgttaaagct
    12241 gcaaatccag caatccccat ctcacaaatc gttgcttctg ttcctccagc aagaatgaca
    12301 tcagaatagc catgtttgat gttacggaat gcttccccaa ttgaattcgt tccgctagca
    12361 caagctgtta cgatagctgt acaaatacct tttgcaccta cacgcaaagc aatatttcca
    12421 gctgccatgt tggcaatcgc cattggtacg aacattggag aaactcgttt tgcacctttt
    12481 tcatgtagac gaataacttg gttttcgatt gttggaagac caccgatccc agatccgatg
    12541 atgacgccaa accggtcttg attcattttt tctttatcta aaccgctcat ctccattgct
    12601 tctaaagcag cgtagattcc atagatcgaa aacatatcca ttcgtttgct atctttttta
    12661 ataaaatatt tatcgtaagg gaaatctttg acttcacccg ctaaggtaat ccctgtttct
    12721 gaagcatcaa atttagtgat cggtgcgatg ccattcgtcc cctcttttaa gctattcaaa
    12781 aagctgtctg cgtcatttcc aataggtgaa gtgactccat agccagtaat taccactcga
    12841 ttcatttgtt tgctctcctt ttcttatccg tgcatgacca atccgccatc gacattgatg
    12901 acttgtccgg tgatatatgg attttgtgct aagaaaactg ctgtttgtgc aatatcttct
    12961 acttgtccga aacgctgcat cggaatttgc ttttccgctt gttccttgac tttgtctgct
    13021 aaaacttccg tcatatcagt tgtgatgaat cctggcgcaa tggcattaca tgtaatgcct
    13081 ctagttgcag cttctcgtgc cacagatttt gttaatccta ctacgccagc tttactagct
    13141 gcataatttg cttgaccaat atttccaatc aacccagata cactagagag attaatgatg
    13201 gccccttctc gctgcttcat catttttttc aatacgtgct gcgtcatatt gaaggttcca
    13261 atcaaattga tatccagaca ttttttgaaa tcttctgcat ccattcgcat cacaagtttg
    13321 tcatttgtga ttccggcatt gtttactaac acatggatcg atccaagctt ttcttctgct
    13381 tctttgatca tttgtcccgc tttctcataa tcagagatgt caccggaaac tcctacgcat
    13441 tttacaccga atgcttcgat ttcttctatc ttttcttttg gaatctctcc gcgaccattc
    13501 aaaatgatat ttgctccagc ttttgcaaaa gctaaggcca tcgctttgcc gattcctctt
    13561 gtactacctg tgataaatac attttttcct tttacatcca taacgttcct ccttatagta
    13621 ttgctattgt ttcatcaaat gtctgcttat tctcaacacg cagaactggt attgttttat
    13681 cgattttttt cataaatccg cttaatactt ttccggggcc gacttcgatg acttgttcga
    13741 tgccgattgt ttttaactta tggatactct catagaaacg aacaggttgc atgacttgct
    13801 gttcaagtag tcccgcgatt gtttctttct tcattatttc cgttgttgtg ttgcttatga
    13861 taggaaaaga aggttcagag aattgaatct gacttaggtc cttcgccagt ttttttgctg
    13921 ccggttctaa aatagctgta tgaaaaggcc cgctgacatt tagagggatc attcttttga
    13981 accctttttc ttttaatagt aaaacagctt cgtctactgc tttttcttcg ccaccaatca
    14041 cgatctgctg aggtgtatta taatttgcag gagatacgat gccgtacttg ctagcttcat
    14101 gacagctttc ctcgatcgtt tcaatcggcg cattcatcac tgcaaccatt ttcccgcttc
    14161 cagctggggc agcttctgtc atataagcgc ctctttttgc tactaacgca actgcttcag
    14221 tgaaggatag cgcattacta gctactaatg ccgaatattc tcctaaactc agtcctaaag
    14281 ctgcatctgg gatgattcca tgctccttca ataagcgata atacgcgatg ctgactgtta
    14341 gaatagctgg ctgtgtatat tgcgtctgat ccaaacgttc attttctgta aagcaaagtt
    14401 cagccatatc gtagccgaga atctcacttg cttcatcaaa tgtctgcttt acaacggctt
    14461 cttcatataa atcttttccc ataccttgat attgtgcacc ttggccacta aataagaatg
    14521 ctgttttcat gtttttctcc aatatatcca gaatatatgt ttgattcttc ctattcaaaa
    14581 aggccgagac attcctattt caggaaatgt cccagccccc aacctaattt taatgattat
    14641 gcagtttgtt tttctacgta agtcactaaa tcttgaaccg ttttgattcc gtcttctgtt
    14701 tcgattttca cgtcaaattc atcttcaatt tcattgatga tttggaataa atccaagctg
    14761 tcagcttcta agtcttcttg gatgtcagta gtcaatttga tttcttcagt ttcttttcct
    14821 aattcttctg cgatgatttc ttgaattttt tcgaatacca taataatata ttcctccgat
    14881 attgtttgct ttttattttt ataatttaac agtctacaac tccatgagaa tacttcccca
    14941 tgttaaacct ccgccatagc ctgtaaatat tactttctgc tgttttccta aggtgatctt
    15001 tccactagaa actgcttcat ccaataagat agggatgctt gcagcagatg tattcccata
    15061 tttatccata ttggtcagga acttttcttg cggcatcttt acttttcggg caattttctc
    15121 aataattctg aggtttgcct gatgcaaaag cagataatca actggtttgt ctttcatgac
    15181 ttcttggata ttgtttgcaa cgtctcgtac ggcaaaatca aaaatatctc tgccagtcat
    15241 ttgcaaataa tacgaacctt ctgaatcttc tgaatagaac ggatttttat tttgctggta
    15301 gccagcggtc aatgagctac ttctggtacc gtcagctgct aatttttctt tcagcaattt
    15361 tttctgtgga ttcgcttcta agagaatccc acctgctcca tcgccaaaca acacagcagt
    15421 cgtacgatca gaccaatcga ttagcttaga tagtgtttca ccaccaatca ccagtccctt
    15481 agttgagccg cagcggatca ttttttcagc catgcttaac gcataaacaa atcctgagca
    15541 cgcagcactg atatcaaaag cgatagcatg agttgctccc aatttccctt gtacttgtgc
    15601 tgctacagat ggtgtcgtgt aatcgggcga cattgttgct actaaaataa aatccaaatc
    15661 tttagggttt agatttttct gttttatcaa tttttccgcc actaaaatgc ataaatcaga
    15721 agtctcctga tttgttacac atcttcgttc acgaataccc gtccttgacg aaatccattc
    15781 atcagaggta tccatcatct tggaaagatc attattagta ataatctttt caggaaggac
    15841 gctggctgtt gcagtaatca ttccaaattg ttccattaaa tatcctcact tatagtcttg
    15901 caagaagtcg tgcaagtttt tcagtgcatc cagcaaggca tgctgttcct ccgtagccat
    15961 tccgtctaag atgttcttga ccatttcacg atgaaaatgc tgatggaccc gaaatagtaa
    16021 ctttcctttt ttcgttagtc ccaactttac aacgcggcgg tcatcttcac tgcggatacg
    16081 ttcgacatag ccttttttta ctaacttgtt aatagcagtg gtcaaggtcc caacagtaat
    16141 tgatagttct ttggctactt ctgaagttgt ttttttcttg tacatcccga ttgcctcgat
    16201 cgtgtgcatc tctgtgattg acagatcttt gaattgagat tttttcagct cagactcttc
    16261 gattgtcaaa atatcattga agacactaac aagataatca tttactgttt ttaaatctgg
    16321 ttccatgttc caccgtccac taattagttt gattatcaaa tcttttgatg ttcaaactat
    16381 atcttaactt ttttcaaaat gcaaccttaa aagatcattt ttttactata tgagcttttt
    16441 ttaagatttt actcatttaa aacaactgat aaatcagcat ttataatttc ttttattaga
    16501 aaaatcatct atctcacata ttttgattat caaagtattt tctgtgaaca gaactataga
    16561 attccctaaa acttgtccat tatttcaaaa tttgttatag tctttttatt caaagcgtaa
    16621 aaggagatcc tatgttaaaa gaaaaaatga aaactctccc catgctgccg ggtgtctatc
    16681 ttatgaaaga ccgagatggt aaggtcatct atgttggtaa agcaaaacgg ctcaaaaata
    16741 gagtaagcag ctattttcat cagaataaac agcattcaaa aaaagtatta cgtatgattc
    16801 atcatataac agattttgat ttcgtcgtag tagacacgga attagatgct ttattgctcg
    16861 agtgtcaatt gatccaacat taccgtcctt tttataaccg acaaatgaat tatttcagta
    16921 attataatta tgtacatatt accaataagg gatttgtatt aacagatact cctacggctc
    16981 gaacatacgg gccttttcgt ctctataaaa aaatgccgtc tattttgcgt ataatggaag
    17041 aaacttatca aatgccttgg ttgtctgaaa ttagtttgtt agctttgcga gtccagcttc
    17101 ctgacctaca ggaaatgact tttgaacaga aaaaaaagga actccaaggg ctgtttcaag
    17161 gccgaaataa aaagctactg acttacttga aaaaaagaca acaacatttc atctatcagt
    17221 tgaatttcga aaaagccggt atgcttcaaa aagatatcga attagttact tattttatta
    17281 gacggatcca ggaacaaaag cagtttttaa gaacaccatc gctcaccttc agcatgccat
    17341 tagcagcaga tgagagtcag aaaaagcact acctcgtttg ttatggtcaa cttgcagaaa
    17401 caatgattac ctctggtgac gtttctcctg acttctatta tgaaaagaaa gaagctcatt
    17461 tatctttgaa acgtcaattg tcaaaagaag aaatcgatcc tgtacaaatc ttgatcagtt
    17521 accgcaaaaa attagaaaaa gaacagtttg aaattgaact gttaaacaaa aaagaagctg
    17581 aaaagcaact aaattagttg cttctcggct tcttttaggc atcttcaact tcaaatgtca
    17641 attatcctaa aatttattgg attaagtcat agatttccat cgctacgata tcgatattat
    17701 caaattcgta ttgctgatga gtatctgttt cagttaattc aaatgtatcg gtcgctttat
    17761 cataagttac tgtacacttc tctacgcctt ctttttcaaa acggcgaact tgcagttcat
    17821 tatctgctga ctcgaccata gcctccagtc gttttatgat tgcgactaat tgtgaatgtg
    17881 tcatcggagg tcctcctttt cttatttctg ttatattgta tcaaaagcat agcctacttg
    17941 cattgatttt ctctaaaaaa actcgttttt tatgattttt tttctggtat ttttccttca
    18001 ggccaccaaa gtttgatcaa agcttgggtt ccgtcattct caaaaccttt atctgccaac
    18061 tcttcatata gtttcaatgc ttgggtagtt gctggcaata caagatccat tttttctgct
    18121 tcttctaatg caatctttaa atctttgata aaatgtttga caaaaaaacc aggtgtgtaa
    18181 tcttctttta aaatacgagg agaataattg cttaaagacc agttagctgc acttccacct
    18241 gaaagcgtct caatcacttt ctttaaatca agtccgtttt tttgtgcata gacaagcatt
    18301 tccgtcattc ctgtcatcgt acctgcaatc atgatctgat tagccatttt tgtatgctga
    18361 cctttcccag cagaaccatg caatgtaaat gtcgtaccaa attctttgaa taaaggcagt
    18421 acttgatcat aaacggcttc ttctccaccg accatgatcg tcagtgtacc attctttgct
    18481 cctaagtcac caccggatac cggtgcatct aacgcatctg cgcctttttc ttttgctgtt
    18541 tttgcaattt tttctgccag gcttggtgta cttgtagtca aatcaactaa aatatgtcct
    18601 gagatatctg cagaaaaaat ccccgactgt ccatagtaga tttcttctac atctttgggg
    18661 taacctacca ttgtaaagag aatattactt tgttctgcta ccgcttttgg tgtatctgcc
    18721 cagatagctc cttctgttac taaaggatca gcttttgctt ttgtccgatt atagacagct
    18781 acttcgtgtc ctgcttctag tagatggcgt gcgacagcac ttcccatgac gcctgttccg
    18841 ataaaaccaa gtttcatttt ttcgacctcc taaaaatcaa aaatccttgc ttctatgcta
    18901 gtatacgcta gaaacaagga ttttttcata aaaaatgttt gaattttatc ttttaaatga
    18961 atttaatttt attttgattc gttcaatcga gtcttcttct tcttttcttc gcatctcttc
    19021 ttcatgataa acaaccatgt cttgataaaa ttcgatcata gcttcgccga aatgtgtaga
    19081 tgaaatatca taaagtttag cttctaaaac ttttggatct ttaggaactt cactggaaat
    19141 ataatcaata agtgctggtg caaagtcttc gtcggtttca aaagttttcc ctaatgaagg
    19201 atgatcgaac aatcggttca aataagcatt tccttccacg acacaaggtg ttccggctgc
    19261 catcgcttct gtataagtaa gcccttgtgt ttctgaagta gaagcactga caaaataatc
    19321 tgccgcttta taataaagtg ctacatcatt gttgtccact tctcctgtga actgcacaaa
    19381 ttcttctaac tgcagttctg agatcaattc ctctaactct tctacataag gtccttttcc
    19441 tacgataact aatctggcgt taggataagc ggagatgacc tgaggaaacc cattaatcaa
    19501 ggcttggata tttttctcat aagaaatcct gcttaaagaa agaatcatca aatggttttc
    19561 ctgaagacct agtgactccc ttaatttgct gatatcctgc tgagtgatat cagaacgttt
    19621 gaatttttca atgtcgatac cagtaggaat cacgcgaagc ggtgctatta caccatagct
    19681 gcgtaatgta tcaataacac gttcacttgg acaaactaca cctgtcgtat gatttgcaaa
    19741 taatctagac aagtatttta catgggattg cctgatcact tttcctttac cgatataatg
    19801 aaggtagtct tcatacatcg tatggtaagt atggatcaga ggtattttca acttcttagc
    19861 taccatcttc ccaagtatcc ctgctccgaa ttctgtatgg gtatgaataa gatctagttc
    19921 tagttctttg gcaaccaaat aagcatacca catgcctcta acaacaactc ttcgatcctt
    19981 gaaagaaata aatggtacac ttggcattcg aatcacatct ttttccaact tatccgcatt
    20041 aggatcggtc gttgtaaaaa tatagacttc atgcccatgt ctttctaatt cttgttttaa
    20101 tgttttgatc gatgtagcaa ctccgctgac ttgcggaaag taggtatcgg taaaaaagcc
    20161 gattttcatg tttttcgcct ccaaactagt ccttgacctg atttactttt tttaatttgc
    20221 tagagacttt ttcattcagt acactttcgt atacattttt aagttcttca ccgattttat
    20281 tgatacttcg ctcttttgct gtttgataac cggcttgtgt cgtactcggt agttcttgat
    20341 tggtaatctg ttggatcagt cggataaatt cttcgtttgt cttccccata tagcagttct
    20401 tgctatcttc taaccagcca ttatacactg gaatatctcg aacaagtacg ttttgtttgc
    20461 ttgctaaagc ttctaaaaca acgatccctt ctgtctcttc ataagaaggg aaaaagaata
    20521 gatctgcacc tgaatacgca ccttctatga tctctccacg aatgtaacca ggaaacagga
    20581 cattttcagg atgatcttct tttacaattt tccggatgtt ccgaggaatc gagtacatgg
    20641 gaacatgacc aaaccaaata aatgtgtatt cgggcatctt cttagcaatt tctacgaaat
    20701 caatgattcc tttacgttcg aaaaacaaac cgacacaaat gattactttt tgatccggag
    20761 acagtttgaa atattctctg aacttttgtt ctttcattgg atcagggtga tatttctcta
    20821 agtcgatccc attggaaata gcttgaatcg gcacacggat accatagctt tccaacaact
    20881 gttttgaata aggtgttggc gtgatcagat agtccgcttt ttggtacaat cctaccagat
    20941 atttttttac gataggagaa agctggttcg atccgataaa ggaatttcgg aaatcttcct
    21001 ctgtagaatg cgcatgatag acaacttttt ttccttctct tctggcttta ttgaccatat
    21061 tatgactatt gattccgtat gtattgatgt gcaggatgtc ataatcttct ttttcatcta
    21121 gtgtataaga gataccgact tccgtcagag cacgtttttg atgatcaagc gcacgcccga
    21181 ttccagattt tgcaagcatc ttttcacttt caaaatataa taataccttc accttacgtc
    21241 ccccttcact tatatagtat aacatagcct acaaactgtc actcaaactt aagccctatt
    21301 tttgtctatt cttactgaca aaaacgtttt cttaaaaaag aacaaaaaaa ctggcgtagc
    21361 tcttttacaa gccacaccag cttttgatac gttgtttatt ttacatattc atgaacaagt
    21421 tcaacgactt cttccatcgt atcgcattct ttcaatgcac gatcagcaag ttcagccatt
    21481 ttcgctgtgt ccaagcgttt cattaaacta cgcgttttaa gaatagatgt cgcactcatt
    21541 gagaactcat ctagacccat acctactagc aatggaacag ctgtttgatc tccagccatt
    21601 tctccacaca tacctgccca ttttccttca gcgtgtgctg catcaattac atttttgatc
    21661 aaacgtaaaa ttgatgggtt atatggttgg tacaagtaag aaacgcgttc gttcatacgg
    21721 tctgctgcca ttgtgtattg aatcaaatcg ttcgtaccta cagagaagaa atctacttct
    21781 tttgcaaact tgtctgctaa gactgctgct gctggaatct cgatcatgat gccgacttgg
    21841 atcgtatcag atacttcctt gccttcactt atcaattttt gtttttcttc ttcaaagatc
    21901 gcttttgctg cgcggaattc tttgagtgta gctaccatag ggaacatgat acgtaaatta
    21961 ccatgaacag atgcacgaag caatgcacgc atttgtgtac ggaacatttc gtcgccttgt
    22021 tcagataaac tgatacgcaa tgcacgatat cctaagaatg gattcatttc atgaggtaat
    22081 tgcagatatg gtagttcttt atctccaccg atgtccattg tacgaacaac tacaggtttt
    22141 ccttccatac cttctaatac agctttgtaa gcttcatatt ggtcatcttc tgttgggaag
    22201 tctggagaat ccatatacag gaattcagta cggtacagac caactgcttc tccaccatta
    22261 ttatggacac caactagatc ttttggtgtt ccgatgtttg cagctaattc aaaatgcttg
    22321 ccgtcagctg tgacagtttc tgcatttttt aatttttccc attctgcttt ttgtgctgcg
    22381 taatctgcac ctgctttttc aaattcagct ttttgttcat ctgtaggatc gatgattaca
    22441 tcgccttcga tcccgttgac agccaaaata tcgccttctt tgactttagc agtaatttct
    22501 tttgtcccaa cgattgctgg aatttctaaa gaacgtgcca tgatagcaga atgtgaagta
    22561 cgtccaccaa tgtctgttac aaacgctttt acaaaattgc gatctaattg tgctgtatca
    22621 cttggagtca agtcatgtgc aacaacgacc acttcttcgt tgatcattga tggatttggt
    22681 aaagtaacgc ctaataagtg cgctaaaata cgtttagcaa cgtcacgaat atctgcagca
    22741 cgctcttgca tataagcatt atcttccatt gcttcgaaca taccgatata catatccgtt
    22801 acttctttta gcgctgattc agcatttacg ctgttgtctt taatattttg cttgatttga
    22861 cctaccattt ctggatctga aagaaccatc aaatgggcat caaatacttg cgcttctgct
    22921 tcacctaagc tttgcgctgc tttttcacga atttgctgca attcttcagt agatttagct
    22981 aatgcagcat ccaaacgagc ttcttcagcc gcagtatctt ctactgttgc cttactgaat
    23041 gttaaatccg gttgaactag caggtaagct tttgcaacgg ctacaccgtc actagcggca
    23101 atccctttta gcatttcaac cattattcag ataagccttc tttcttcatt gtttcaacga
    23161 ttgctgccat tgcatcagct tcgtcagcac cttctgcagt aatagtaaca tcagaacctt
    23221 gacctacacc taaagacata acgcccatga ttgatttcaa gtttactgat ttacctttat
    23281 actctaagtt tacatcagag ttaaatttgc ttgctgtttg tactaatagt gtagctggac
    23341 gagcgtggat cccagtttct gctactacgt gaaattcttt cttttccata ttaatcggtc
    23401 tcctttaagt gagtgttgtt tttatgtgag ggttttcttt tttagtaatt cagagaatcc
    23461 taacaaatgc caccctttca tctgtaaaga ttaacatttt ttttcgttag atacaacagt
    23521 tttcattcaa tttcagataa aagtattcaa attattccgg attctttttc atccttttct
    23581 tcacatttta taacaaacgt gtttatttcc tttttcttgt cgctttctct tctcctgacg
    23641 tttatcattc tttcctttga ccctctttgt tttcatatga aacgaattac ttgcttccct
    23701 ttttattttt agtataataa gagtcaaagg tcaggaatgg tcaatagaga tttcaccttt
    23761 tctacctcat aaatctctta aaaaactagg ggttattctt ttacctcatg aaaaacgaga
    23821 tgtaaaatat ggatgtaccc atttttgtga aaggacgtga atgattcatg ctttgtcaaa
    23881 actgcggcaa gaatgaggca acgattcact tgtatgccac tgtcaatggt cagcggacac
    23941 aactcgatta ctgtcagagc tgttatcaaa aaatcaaaaa tcaacaaaat ggaggtctga
    24001 ctaatatggc ccaaaatgat ccatttggat ttggcagttt ggacgatctt ttccgttcca
    24061 tgtctcgcca aatgcaacag caaggaaatt atgagcaaac accaccaaca caatttggcg
    24121 gaaacaacaa cttcaatggt ggtcagccac ctcaaggcaa tacagaaggt ttattgggag
    24181 aatacggaat caatatcaca gaacaagcac gacaaggtga tatcgatcct gtgatcggac
    24241 gcgatgacga aatcaaacga gtcattgaaa ttttaaatcg ccgaaccaag aacaatcctg
    24301 tcttgattgg agaaccaggt gttggtaaaa cagcagttgt tgaaggttta gcacaaaaaa
    24361 tcgtagatgg tgatgtaccg caaaaattaa tggacaaaga agtcattcgt ttagatgtcg
    24421 tatctttagt ccaaggtact ggtatacgag gacaatttga agaacgtatg caaaaattga
    24481 ttgaagagat ccgtcaagca gaaaatgtga tcctattcat agatgaagtt cacgaaatag
    24541 tcggtgctgg ttctgctggt gatggaaata tggatgctgg taatatttta aaaccagctt
    24601 tagctcgagg agaattgcaa atggttggtg ctactacctt aaatgagtac cgcatcatcg
    24661 aaaaagacgc tgctttagaa cgtcgtatgc aacctgtacg ggtagatgaa ccaactgtcg
    24721 aagaaacgat cagtattttg aaaggtttgc aaaaacgtta tgaagactat catcatgtaa
    24781 aatatactga tgaggccatc gaagcagccg caactttatc caatcgttac gtccaagatc
    24841 gcttcttgcc ggataaagcc atcgatttgc tagatgaaac aggttctaag aaaaacttga
    24901 cgatccaaat cgttgatcct aaaacaatcg agaaaaaact gcaagaagca gaagaacaaa
    24961 aagttttagc ttctcgagaa gaagatttcg aaaaagcagc ttattatcgc gatcagatca
    25021 ataaacttca aaaaatgaaa gaacgtcagc tcactgaaga ggaaacacct gtgattaccg
    25081 aaaaagatat ggaaaaaatc gttgaacaac ggacaggtat tccagtgggt gaattaaaag
    25141 aaaaagaaca gacacaactg aaaaacttag cagatgactt gaaagctcat gtcatcggac
    25201 aagataacgc tgtagatcga gtagcgaaag cgattcgccg aaaccgtgtt ggattaaaca
    25261 aacagaatcg tccaatcggc tccttcttat ttgttggacc aactggtgta ggtaaaacag
    25321 agcttgcgaa acaacttgcc tacgaactat tcggttcaca agattcaatg attcgtttcg
    25381 atatgtctga atatatggaa aaacatagtg tctctaaatt gattggttct cctccaggtt
    25441 atgtcggata cgaagaagct ggtcaattaa cagaaaaagt acggagaaat ccttacagtc
    25501 ttgtcttgtt agatgaagta gaaaaagctc atccagatgt tttgcatatg ttcttgcaaa
    25561 tcttagatga tggtcgattg acagatgcac aaggaagaac ggtcagcttt aaagatacga
    25621 tcatcattat gacaagtaat gccggaactg gtaaagtaga agcaaacgtt ggttttggtg
    25681 cggcacgcga aggtgttact cgttctgtat tgaaccaatt aaacaactac tttacaccag
    25741 aatttctgaa ccgttttgac gggatcatcg aattcagtgc attatcaaaa gaaaacttga
    25801 tgacaatcgt cacactaatg ctagacgatg tcaaccaaat gctggcagca cagcaacttc
    25861 acatcgaagt tcctacgaat gtcaaagaaa aattagttga cttaggctat gatccatcta
    25921 tgggtgctcg tcctcttcga cgcacgatcc aagaacaaat cgaagatggt atcgctgaat
    25981 tttatcttga tcacccttct atccatgagt tgaaagcaaa actggataaa gatggaaaaa
    26041 tcatcgttac ttctaaacca gaacgtttgg ctaaagaatc agccgaagaa acggctgaat
    26101 aaatccagtt ttatagcgtg agacggtatt tctttgagaa atgccgtctc attctttttt
    26161 cagaaaagtc aaaatactgt tcattttata aaaaagaaat tataataaga gaaacaagca
    26221 attaaaaata cataaaagag gtgagcgcca tgaaattggt aaatgtaaca aacagccatt
    26281 cccgtcttgt attaaaccag cttgaaaaca ctgatgccca tctagtcaag gtctacacag
    26341 ccggaaatac cactattgtc tacactgaag cccctgaaca taatgaaatt ctgctgatca
    26401 atgacaaacg taaaatccag ccgaaagaaa tcgaagatgc taaaaattat ttcttagata
    26461 aaatcaaaga cgccgtttac cacgaggatg aaatcaaagt aatcgaattg gcaggccttg
    26521 ttgaaatctc gattccaaaa catgaattag gcgctacatt agccgtgtaa acaaattttg
    26581 aacataataa ttaaagagcg tgggacaaaa gtaaag
//
LOCUS       DACDLM010000034        26025 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.034, whole genome shotgun sequence.
ACCESSION   DACDLM010000034 DACDLM010000000
VERSION     DACDLM010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26025
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.034"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(41..679)
                     /gene="plsY"
                     /locus_tag="IV356_001533"
     CDS             complement(41..679)
                     /gene="plsY"
                     /locus_tag="IV356_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HAP9015224.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            806..1240
                     /locus_tag="IV356_001534"
     CDS             806..1240
                     /locus_tag="IV356_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HAP9015225.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            1406..3451
                     /gene="parE"
                     /locus_tag="IV356_001535"
     CDS             1406..3451
                     /gene="parE"
                     /locus_tag="IV356_001535"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HAP9015226.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            3463..5913
                     /gene="parC"
                     /locus_tag="IV356_001536"
     CDS             3463..5913
                     /gene="parC"
                     /locus_tag="IV356_001536"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HAP9015227.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDRSIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            6190..8421
                     /gene="pflB"
                     /locus_tag="IV356_001537"
     CDS             6190..8421
                     /gene="pflB"
                     /locus_tag="IV356_001537"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HAP9015228.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            8665..9426
                     /gene="pflA"
                     /locus_tag="IV356_001538"
     CDS             8665..9426
                     /gene="pflA"
                     /locus_tag="IV356_001538"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HAP9015229.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            9511..10437
                     /locus_tag="IV356_001539"
     CDS             9511..10437
                     /locus_tag="IV356_001539"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HAP9015230.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            10619..11512
                     /locus_tag="IV356_001540"
     CDS             10619..11512
                     /locus_tag="IV356_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HAP9015231.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            11646..11771
                     /locus_tag="IV356_001541"
     CDS             11646..11771
                     /locus_tag="IV356_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP9015232.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(11905..12537)
                     /locus_tag="IV356_001542"
     CDS             complement(11905..12537)
                     /locus_tag="IV356_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015233.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(12685..13227)
                     /locus_tag="IV356_001543"
     CDS             complement(12685..13227)
                     /locus_tag="IV356_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HAP9015234.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            13362..13751
                     /locus_tag="IV356_001544"
     CDS             13362..13751
                     /locus_tag="IV356_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015235.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            13755..14519
                     /locus_tag="IV356_001545"
     CDS             13755..14519
                     /locus_tag="IV356_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAP9015236.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            14648..15595
                     /locus_tag="IV356_001546"
     CDS             14648..15595
                     /locus_tag="IV356_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP9015237.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            15725..16465
                     /locus_tag="IV356_001547"
     CDS             15725..16465
                     /locus_tag="IV356_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015238.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(16756..17424)
                     /locus_tag="IV356_001548"
     CDS             complement(16756..17424)
                     /locus_tag="IV356_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP9015239.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            17558..17845
                     /locus_tag="IV356_001549"
     CDS             17558..17845
                     /locus_tag="IV356_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015240.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            18261..19799
                     /locus_tag="IV356_001550"
     CDS             18261..19799
                     /locus_tag="IV356_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HAP9015241.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            19796..20761
                     /locus_tag="IV356_001551"
     CDS             19796..20761
                     /locus_tag="IV356_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9015242.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            20748..22070
                     /locus_tag="IV356_001552"
     CDS             20748..22070
                     /locus_tag="IV356_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP9015243.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      22133..22237
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            22311..23054
                     /locus_tag="IV356_001553"
     CDS             22311..23054
                     /locus_tag="IV356_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9015244.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            23069..24061
                     /locus_tag="IV356_001554"
     CDS             23069..24061
                     /locus_tag="IV356_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP9015245.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            24073..24810
                     /locus_tag="IV356_001555"
     CDS             24073..24810
                     /locus_tag="IV356_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9015246.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            24800..25522
                     /locus_tag="IV356_001556"
     CDS             24800..25522
                     /locus_tag="IV356_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAP9015247.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(25606..>26025)
                     /locus_tag="IV356_001557"
     CDS             complement(25606..>26025)
                     /locus_tag="IV356_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HAP9015248.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         8953 a         4426 c         5428 g         7218 t
ORIGIN      
        1 ttgtcacact cccgttttat ctctttggaa tgaaaaagta tcaggatttt ttcttgctgc
       61 tattcaaacc aaacgggatt cgactttcag tatggtttct gatacgcttg atattgtctt
      121 tatgccgata aaagataaag gaagaaacta aaaaggcaat gatcgtcagt aaccaattgg
      181 gcttagccaa aatcacagga gctacataag gaaggacgat cgtagataaa gtgatcaata
      241 ctgcactgat catactgctc aaactcacca tacttgtaca aaataaacta acgataaaga
      301 tgatacaaga ataaacaaaa aatacaggat taaatcctaa aagcattcct gcacttgtcg
      361 caacagcttt tcctcctttg aacccagcaa aaatcggaaa tgtatggcca agaatggcgc
      421 ataccccaaa ccaaagaggg ttaatcccag aaaggtggaa gatcatcggc aaacaagtag
      481 ccaatgtacc ttttaaaata tccataagca ggacaacaat cccggctgtt ttgcctaata
      541 cacgaaatgt attggtcgtt ccagtattac cgctcccgtg ttgtcggata tcttttttga
      601 aaaacaattt gccaatccag acaccggaag gaatagaacc taaaagatat gctaaaataa
      661 gtaataagat caatttcatt ttttaccctc tttcaagttg aaaactatcc tttattttag
      721 catgaatagg taacaggaac aattgaaaaa atgaaagata caagtataat agatggaata
      781 aaaagaaaag caaggggtgg cagaaatgtc tgtaaaaaat ccaacacaag aaacgatttt
      841 caactatttg gaagaagcaa aaaatattgc cgtcgtaggc ttgagcaata aaccagaacg
      901 aacaagttac atggttgcac aggtattgca agacaatgga tataaaatca taccagtaaa
      961 tccattattg gctggtgaag aaattctagg cgagaaagtc tatgcgaatt tgacagaaat
     1021 cgatgatcca atcgatatcg tagatgtatt tagacggagt gaatttttac ctgaaatagc
     1081 aggtgatttt ttgaaaactg atgctaaagt gttctgggca caattaggga ttgaaaacaa
     1141 agaagcagct gagatgctaa gaaaagcagg acgtacagat atcgtaatgg atcgttgtat
     1201 taagattgaa cttggtaagt tgaaagaaaa ccaaaaataa aaatgaccac aaagaagaga
     1261 tgatcgatag aggggaatgt cgaaaaagcg gttaggagat aattaaaatt gatttctcgt
     1321 ctaccctctt ttttttcacg accttttcta gtatgataat cgtggtgcgg ttttgccgca
     1381 aagtattatt gaaggagcgt ttgccttggc aaaaaaagta aacaacgaat acaatgactc
     1441 gtccatccaa gtattggaag gattagaggc agttagaaaa agaccaggga tgtacattgg
     1501 atccactgac agccgaggct tgcatcattt agtctatgaa atcgtcgata atgcagttga
     1561 cgaagcatta tcaggttatg gcagtgagat tgatgtgacc atccatgaag acaatagtat
     1621 aactgttgca gatagcggac gtgggatgcc tgtaggaatg catgcttccg gaataccaac
     1681 agttgaagtg atttttactg tgctgcatgc tggcggaaag tttggtcaag gagggtacaa
     1741 aacttctggt ggactgcacg gtgtaggagc cagtgtggta aatgccttat cgaaatggct
     1801 aattgtaacg atcgttagag atggcgtaga gtatcagcag aaatttaaaa acggcggtaa
     1861 acctgacggt actttgaaaa agataggaaa aacaaaaaaa gcaaacggga cgactgtcca
     1921 ttttttacca gatgatacaa tattcagtac aacgaaattt tcatatgaaa ttttagccga
     1981 acggttaaga gaatctgcct ttcttctaaa aggcgttaaa atctctcttt ctgatcttcg
     2041 tggagaagaa ccagtcaagg aaatttttca ttacgaagaa ggaatcaaag aatttgttga
     2101 ttatctgaat gaagaaaaag atacattgac accagttgtt tatttttcag gagaaaaaga
     2161 aggtatcgaa gtagaggtcg cttatcaata caatgacggt tattcagaaa atgttttatc
     2221 ttttgtcaat aacgttcgga caaaagatgg gggaacccat gaagctggta tgaaagcggc
     2281 gatgacgaaa tcttataatg aatatgcgag aaaagttggt ttgctgaaag aacgggacaa
     2341 gaatctggaa ggtagtgatt tcagagaagg gttagctgct gtactttcta tccgtgtacc
     2401 tgaaaatctt ctgcaatttg aagggcaaac aaaagaaaaa cttggtacgc cagttgctcg
     2461 taccgtagta gataacgtca tcagtgaaca aatgggcttt tatttgcagg aaaatagcga
     2521 aatgagccag atgttggtcc gtaaagcaat caaagccaga gaagcgagag aagcagcacg
     2581 taaagccaga gaagaaagcc gaaatgggaa gaagcgtaaa aaaggcgaat ctcttctttc
     2641 aggaaaattg acacccgcac aatcccgaaa ccctaagaaa aatgaattgt atttagtcga
     2701 aggggattct gctggcggat ctgctaaaca aggaagagac agaaagttcc aagcaattct
     2761 acctttacga ggaaaagtca tcaataccga aaaagctaaa atgcaagata tcttgaaaaa
     2821 tgaagaaatc aatacgatga tctatacgat tggtgcagga gtcggtcctg agttttctat
     2881 cgaagactgt aattacgaca aagtaatcat catgaccgat gcggatacag acggcgccca
     2941 tattcaagta ttactgctta ctttctttta tcgttatatg aaaccgctga ttgaagctgg
     3001 gaaagtatat atcgcgttac cgcctttata taaagtatcc aaaggacaag gaaagaagca
     3061 agtcattgaa tatgcgtgga cagatgacga attggcagca atgattaaaa aagtcggcaa
     3121 aggatatatg ctgcagcgat ataaaggact tggagagatg aatgcggaac aattgtggga
     3181 aacaacgatg gatccgactt cccgtacgtt gatccgcgtc cgtatcgatg atgctgcgca
     3241 agctgaacgt cgagtaacca cactgatggg tgacaaagta gaacctcgaa gaaaatggat
     3301 cgaaaatcac gtgcaattta cgctcgaaga agatggcagt atcttagata aaaaagagga
     3361 tactgaaatc tctccttcag tttctaatga tttattagat gaagaacgag cagataaaaa
     3421 tgaaaacaat cagttatttg aagtagaata ggaggtcacc tgatggaaaa tcgacaagaa
     3481 gtacaagaat taactttaga agaagtgatg ggtgaccgct tcggacgtta ttccaaatat
     3541 attatccaag aacgtgcact gcctgatatc cgtgatggat tgaagccagt gcaacgccgg
     3601 atattatttg ccatgaacaa agatggcaat acgtatgaca aaggattccg taaatcagca
     3661 aaatctgtcg gaaatatcat ggggaattat catcctcatg gtgaccgcag tatttatgaa
     3721 gcgatggtcc gcatgagcca agactggaag ttgcgggaag tactgatcga aatgcacggg
     3781 aataacggga gtatggacgg tgatccacct gctgcgatgc gttatactga agccagatta
     3841 tccaagttaa gtggagagat gctagcagat atcgagaaag aaacagtcga tctcgtgtgg
     3901 aattttgatg atacagaaaa agaaccaaca gtccttccag ctcgataccc aaaccttctc
     3961 gtcaatggat cgacaggtat atctgctgga tatgcaacag aaatcccgac tcataactta
     4021 gctgaagtga tcgatggcac aatctatatg atcgatcatc cacaagcgag ccttgaaaaa
     4081 ttgatggaat atattcctgg acctgacttt ccaacaggag ggatcttgca aggaaaagat
     4141 gaaatcaaaa aagcttatga aacaggacga ggaaaagtta ttcttcgttc gaaaacaaag
     4201 atagaggcaa tgaagggtaa taaacagcaa atcgtgatca cagaaatccc atatgaagta
     4261 aataaagcga ccttggtgaa aaaaatggat gagatccgtt tgaataagaa aatcgatgga
     4321 atagctgaag tacgagatga aagtgataga acaggtctgc aaattgtcgt cgaattgaaa
     4381 aaagacgcca atgctcaagg aattttgaat tatttgttca aaaacactga gctacagatc
     4441 aattacaatt tcaatatggt cgctatcgac catatgactc cgcatcaagt tggactgaaa
     4501 gacattttaa gaagttatat cgagcatcga aagcaagtca taacaaaacg tagtcaattc
     4561 gatttagcca aagctcaaaa aagacagcat atcgtagaag gattgatgaa agctttatcg
     4621 attctggatg aagtaatcgc aacgattcgt gaaagtaaag acaaaaaaga cgccaaaaag
     4681 aatttagtcg acgtctttca atttacagaa gaacaagcag aagcaattgt cacattgcaa
     4741 ttataccgtt tgacgaacac ggatatcaca gagcttcaaa aggaatccga aagcttgatt
     4801 gcgcaaatca cagagttgaa taaaatcctt tcaaatgaca aagagctttt ctctgttatg
     4861 aaaaaagaat tgcgagaagt gaaaaaaaat tattcttccg ctcgtctaac gacaatcgaa
     4921 gacgaaatcg aagaaatcaa aattgatacg caagtcttag tggcacaaga agacgtaatt
     4981 gtcagtgtga cgcgagaagg ctatgtgaag cgaacaagcc ttcgttctta tagtgcttcc
     5041 aaaccagaag aaatcgggat gcgagaaggc gactacttgc tatactcagg tgaattgagt
     5101 acattggacc atgttcttct gatcacaaat aaagcaaatg tgatctaccg ccctgtccat
     5161 gaactacccg atttgaaatg gaaagatgct ggtgagcaca tttctcaaac aatctccaat
     5221 ctgtctgtag acgaatcgat tttagctgtt ttcccatatc aaaaaattca agcagagaaa
     5281 acatttgtat tcatcagcaa gaatggattg atcaagcaaa cacgaatgac agagttcgaa
     5341 ccatggcgca cctataagag ccgtccgctc agctgtatga agctaaaggc ggaagaagat
     5401 gaactgattg ctgtgtatct gaaagaagat cagccaggct tagatgtttt cttagtaacg
     5461 catcaaggaa tgggtttgcg ctatccttta acagatgttc ccgttgttgg agcaaaggca
     5521 gctggagtga agtctatgaa tttgaaagat ggagatagga ttatcaacgg gctgcttgtg
     5581 ttagcagaag gtgatacgcc gatcgtaatc gttactcagc gaggagctgt taaacgcatg
     5641 cttgctcaag aaatcagcca aacttcacgt gcgaagcggg gagtgacggt catgcgtgag
     5701 ctgaaaaaaa atccgcaccg tattatctat atgtcggaag gaagatcaaa agaaataacc
     5761 ttgatgaatc aaaaagggca gcagttaacg attgacccaa ctgatttccc tataggtgat
     5821 cgaacatcga atggatcatt tgcgatggat gagaaaaaag gtggagaagt catcgaagtt
     5881 atcgatgctc ctgagatttt catcgagtcg taactgttgt agtattttaa tgaagagacg
     5941 ccatctgtat taatacaggt ggcgtctctt tttcattcat ttttaataaa tccttatacg
     6001 tttgcaaaaa aagatgaaag tgttcacaat gcttaaatgt tggtatgtca acgttgattt
     6061 aaatatatgt aaataaaaca taaaaattgt taaataaaaa acaagaaaac ccttgcaaag
     6121 atagggtgct gtgttatact aatcacgtaa aaactgttac ataaaacaga aatttaggag
     6181 gtccatacaa tggagcaatg gaatggattt aaaggtacca aatggaaaga aggcgtagac
     6241 actagagact ttattcaaaa taactacact gaatatcgcg gtgatgacag ctttttggaa
     6301 ggcccaacag aagcaacaga aaaattatgg gatgaattgc aaaagttaaa tgatatccaa
     6361 ttcgagcgta acggtgtcta tgatatggac acagaaatcg tatcaactat tacttcacac
     6421 gatgcaggct atttggataa agatttggaa aaaatcgtcg gtctacagac agacaaacct
     6481 ttgaaacaag cattcatgcc gttcggcgga atcaatatgg ctaacaatgc gctaaaaagc
     6541 aatggctata caccaaacga tgaattgaca catattttca ctgactggcg caaaacacat
     6601 aatcaaggtg tatttgacgc ttatactgct gaaatgcgtg ctgctcgtaa aaacaaaatc
     6661 attacagggc ttccagacgc ttacggtcgc ggacgtatca tcggtgacta tcgtcgtgtg
     6721 gcattgtatg gaatcgacta tttgatggaa caaaagaaaa aagatcatga tatgactggt
     6781 tatcatacaa tgagtgaaga agtgattcgt ttacgtgaag aaatcactga acaatatcgt
     6841 gcattagcgc aaatgaaaga aatggctgcg aaatatggct atgatatttc taaaccagct
     6901 gcaaatgcaa aagaagctgt ccaatggcta tacttcggat atttagcagc aatcaaatca
     6961 caaaatggtg ctgcgatgtc aatcggacgt atctcagcat tccttgatat ctatatccaa
     7021 cgtgatttgg ataatggagt aatcacagaa aaagaagcac aagaattgat cgaccactta
     7081 gtaatgaaat tacgtatggt caaattcgcg cgtacacctg aatataacca attattctca
     7141 ggattcccta tctgggctac tttatccatt gcaggtatgg gattagatgg tcgttcatta
     7201 gttacaaaga atgatttccg tctgcttcat acattaacaa atatgggacc ttcaccagaa
     7261 ccaaacttga ctgttttgta ttctgaacac cttccagaag gattcagaac atatgctagc
     7321 agaatcgcta tcgaaagttc ttcgattcaa ttcgaaaatg ataatcagct tcgtgaacaa
     7381 tggggttctg atgattgtgc gattgcttgc tgtgtatcag gaacagttgt cggaaaagac
     7441 atgcaattct ttggcgctcg tgctaacttg gctaaaacac tattatatgc catcaatggc
     7501 ggagtcgatg aagtgactgg cgcccaagtt ggaccagaat atcgtccaat cacatcagaa
     7561 atactagact ttgaagaagt gaaacataac ttcatgaata tgatggattg gttagcagaa
     7621 ctatatgtca atacgttgaa catcattcat tatatgcatg ataaatattc ttatgaagca
     7681 gctcagctgg ctttgatgga ttctgacttg caacgcacat ttgctacagg tattgctggg
     7741 atctctcatg cggcagacag cttgtcagcg atcaaatatg caaaagtaaa agcaatccgt
     7801 aatgaaaaag gaatagcagt tgattttgaa gtggatggcg acttccctaa atacggaaat
     7861 gatgatgacc gtgcagatga attagtttca tggatcttgg aatacttcat gggacaaatc
     7921 aaacgtcata aaacttaccg caactcaaaa ccaacaactt cattattgac gattacttca
     7981 aatgttgttt acggtaaaaa tacaggaaat actcctgatg gccgtgaagc tggaaaacca
     8041 cttgcgccag gagcaaatcc aagttacaat gcggaacaaa gtgggttatt agctagcctg
     8101 aactcaacag ctaaaatgaa ttacggctgt gcattggatg gaatttcaaa tacccaaaca
     8161 atcaatcctt caggtcttgg aaaagaacaa gatacaagaa tcgaaaactt gcgtaatgtc
     8221 ttagatggat acttctcaaa aggagcttat catttgaatg tcaatgtatt cagtaatgat
     8281 ttattgcgtg atgcaatgga aaatccaatg aaatatccga acttgacgat ccgggtatct
     8341 ggttatgcag ttaaattccg tgacttgaca agagaacaac aattagatgt cttgatgaga
     8401 acttcacacg acagaatgta aaaagttcgt gaaaaaagtt tttcgactta gcgtcgaaag
     8461 gacgttgaat agccatcgca tcaaaatcga ataatcagta tgcttatttg aaagaaacga
     8521 tttacagggg caggacttgt atgttccgtc cctgtaaatt ttacacataa cgaagcggca
     8581 attgcgaaaa attttgttca gaaagcttcg cttcgacagc taacttgtac ttaaaatgaa
     8641 atcaaagaaa agatgtgaac ttaaatggaa gaaaaaacaa tcggctatgt tcattctatc
     8701 gaaactttcg gttcagtaga cggacctgga ctgcgctttg tcgtgtttat gcaaggatgc
     8761 cgcatgcgtt gccaattttg tcacaatcca gatacttgga atattggcgg agggaaagaa
     8821 tacacagcag atgaactttt agataaagca gaacgcttca gaccttactg gggagataaa
     8881 ggtggtatta ctgttagtgg tggagaacct ctattgcaga tcgatttttt gatcgaacta
     8941 tttaaaaaag caaaagagcg gaagatgcat actacattgg atacatgcgg aaaacctttt
     9001 acgtatgaag aacctttctt ttcacgtttt caagaattga tgaagtatac agatttactg
     9061 ttatttgaca tcaaacacat cgataatgaa gagcataaaa aactaacgca ttgggacaat
     9121 gaaaatattt tagaaatggc tcaatatttg tcaaaaatca acaaaccggt ttggattcgc
     9181 catgtactag ttcctgagcg aagtgattat gatgaatatt tgatccgact agacaacttt
     9241 attcaaacct tgtcaaatgt agacagagta gagattcttc cttatcatac gatgggaaaa
     9301 tacaagtggg aaacacttgg tttgaaatat ccattagaag ggatcgaacc acctacaaaa
     9361 gaacgtgtcg aaaatgctaa acgattgctt catacagaag agtatacaaa atatttaacg
     9421 cgataggtcg catcggaaag aagataagta ttgcttcttt ccgttttttt gctattatta
     9481 aataggagaa atcacaaagg agcgaatgac atgtcaaaaa ttttagtttt tggtcaccaa
     9541 aatccagata cagatgcaat cggggcagcc attgcgtttt cacacttgca aaatgaatta
     9601 ggtaaagaaa cagaagcagt tgctctaggt acacctaatg aagaaacaca atacgcatta
     9661 gaccactttc agctatctgc accacgagta gtagagtcag ctaaagcaga aaatgcagat
     9721 gtcatgcttg tggatcataa tgaattccaa caaagtattt cagatatcag cgaagtaaat
     9781 attttagctg tagtagacca ccatcgtatt gcaaactttg aaacagctaa tccattgtac
     9841 tatcgtgcag aaccagttgg atgtacaagt acgattattt taaaactata taaagaaaac
     9901 caagtaacaa ttcctaaaga aatcgcagga atcatgctct cagctatcat ttcagataca
     9961 ttgttgttca aatcaccaac atgtacgcct gaagatgaag cagctgcaaa agaacttgca
    10021 gcaatcgctg aagtcgatct aaacacttat ggacttgaaa tgttgaaagc aggaacaaat
    10081 ctaagtgata aatcagctgc ggttcttctt gatttggatg caaaaagttt cccaatgggc
    10141 agttccaacg ttcgtatcgc tcaagtcaat acagtggacc ttaatgaagt gatggatcga
    10201 caagcagagc tagaagcagc aatggaagat gaaatgaaag caaatggcta cgatctgttc
    10261 gtattagttg tcacaaacat cttagacagt gattcagaat tacttgttgc tggtaaagga
    10321 aaagaaaaag tagaagaagc tttccaaaca actttgacca acaaccgtgc tttgcttaaa
    10381 ggtgtcgttt cacgtaaaaa acaagtcgta cctcaattga cggctgtatt tagctaatca
    10441 aatggtagta tgaagcattc aaaatgaatg gataagcgat tgatataaaa agaaacatag
    10501 aacatactaa aggccgaaga aatggaggag aataacagtc aattatgact cttgttcttc
    10561 ctccttttta cgtaaaagcc ttttaagtaa aataaaacgg atagaaaaga gaacatatat
    10621 gaactattat tcaaaaaata aggaaaactt ttatcaaaaa ctgaccgatg atccgctttt
    10681 ttcttcattg accgattatc tatatgaaca tcgagaacaa gaaacgattc taagagaatt
    10741 gaaaaaagaa ttttcgcaaa ataaattttc ccattttctt gatttattga tcgatgcagg
    10801 attaatcaag agggaagaac gaagatatca tttgaacttt ccaatatttg atcctaaaga
    10861 ttacttgcaa caagccactt cggctgctga aaccatagct gaacaattga agagactctc
    10921 tgttgatgaa caaaaattag cgatgggaga agttatttgg gcgtattgtt tcgaagatga
    10981 acggaaagaa gcgtattttt atggagtaag aaacagccga gagacagaat tgctgaggac
    11041 aactgcagga aatgagaagt accgttttat cacactttcc tctatagaac acttcccgct
    11101 tactttggct aattactttt ttgtacagaa gaatcagctt cctgtaacga aggcattcaa
    11161 agaattagcc gaacttattg gagacgtaaa tgaatcgtac ttttttgatc aaatagaagt
    11221 tatcgttgac aggatacgta agaataaata taaaaatcgc cggcctagta ttttccatca
    11281 gtctctactt gtgacgaata ctataaagga agaagaatca ttcacattag aattacctat
    11341 tgtcgaaaaa aacaattttg agattgaatt accaacattg gatccttcat tgacaatgga
    11401 ggaaatggcc tttcttaaac gacaaatctt ttctgagctg agcaagaaat ttataccgca
    11461 tgcattttct tatatcaaag aatatggaac agttttagtg agtaaaacct aagagagcag
    11521 taagcaaaaa ttatactgac tcttgcagga ggagcctttc tcttccttta tggttaaaag
    11581 aattatttga gtattttgcc tatctaccac ctattagatt cactacatgg tctggaaaca
    11641 aaggaatgca aaaaaatggt gagaaatgtg gaatgacaaa ggaagtagtg ataagaaaag
    11701 ttagattttt aaataatcaa tattatgatt cagtcaagta tggcatttta tgggaagaac
    11761 tagctgatta gattaggaag tccatttgat aatccagaat cactaagaaa cgaatggcga
    11821 gtcattaata atttatccaa tcttgggtta ttcttttaga ttgaagtgtt taaaactaaa
    11881 aaagcattta tgaagtcgta atagtcaggc ttcaaaatgc tttttatttt gtttgttttt
    11941 tctttgccac ataaatacac ctagactgac gatgaagagc atatccaaca gatttcctgc
    12001 gacttggatc gtcgaagggt tggtcagtgg cattaaagca aggacaaaaa aggaaaacaa
    12061 gctgtaaata aaacaggtga caggaactaa tcgaaagaag agcggacatt tcaattggct
    12121 aaaaatgagt gaaaaaataa aataagtaaa aatggataaa atcacgacta aaccattcat
    12181 gataaagaag aaaagcgtat tgtgattaaa cgaataaaaa agaattgcta aaaaagaaaa
    12241 cgttttaaat gcaatcaata cgcttgaagc ttcgtttaac gtaccaggat gtcgatgaaa
    12301 aaaataggca ccgaaataaa cagaaaacag taagccgcaa agagaagaca aaatcaaaaa
    12361 aaacggattt tcttcggctt ctgtgatatc agaatgatcc aaaagcaacc agcctaatgc
    12421 actagaaggc gcatgtgagg tcttaaggta tgaataacat agaaaaaata agatcgtcaa
    12481 agttgcaaaa aaagagccta aatgtaaaaa attagtggtt ctacgttgaa tttccataat
    12541 atctccaaat taaattgata agtatataaa gtataataac aaattgatga gtatatgtcg
    12601 atgtttttta atcaaaataa taaataaaaa ctgtctaaca tttaaaattt aatttagata
    12661 ttagacagtt tttaagtttg tgagttattt tccttgtcgt tttctcactt ttttagtcca
    12721 gaaaccacct gaaatatatt ttggctcata agaaatgata aaagcacgct cttcgatttc
    12781 tttgatcagg cgatacagtt cacgttcgct ttttctagga gaaagtattt cgagaactag
    12841 ccgctcacct tccagcccca ttgcagaagt ctgtgtcaca ccataaccgt gttctctcag
    12901 tatacccggc aaacttttat cttctgcgct atttgctggc aaaatcgttg tgaccatgat
    12961 gtatcctaat gccaatttgt cttcaatcaa aattccgaca ctgataccta ctgcgtaacc
    13021 taacgcatag acaaataaat tcagtggatt atctaaacga tctaaaacaa gggataagcc
    13081 gacgatataa atcgtgatct cgaccatact gacaagtgga gcaatcagtc gatagccttt
    13141 cattgtcaac atgaaacgta acgtgttcag agtgatataa gcaaaattaa tgaggaagat
    13201 catccccaac atttttggat caatcatttg taaaactcct ttcatttata taacaacaat
    13261 atcaaaaaaa atcgtaagtg aagaaaaatt gaaactttat acatacaaaa aaatgataaa
    13321 atgattataa tagaattata aagataggtt aggtgattaa aatgaaaacg gtcaatcgtg
    13381 tgttttgtgc cagccacgtg ctaagtctcc ttctcagtat atacttaggt gtctattcga
    13441 ttcaacagcc aattgaggta gagaacattg tttttcagat gtcgctgaca gatggtttaa
    13501 ttttaagcgt ttttttcttt ttgatactgt ttattggtaa tattttcggt agcgttgcca
    13561 gttttttgaa tttttctatt tatccactcc tttcgctagc attaggagtg gtgggacttt
    13621 gttctctgtg cttatttccc gagccattca gtcctgcatt tatattattt ggtacactga
    13681 acctgttcca gacaactgtt ggagcatggt tgctatggcg atcaggaaat ttaatgaaaa
    13741 taggtgagta acaattgaat ccaattatat tgaaacgttc tgtccatcat attccagtgt
    13801 tagaagttgt tctgaaagaa ttaagagagg aacgtattcc cgttgtcatc tattatcacg
    13861 gatggcagac aagtaaggag ttagttttga cgcaaggaag aaaaattgcg cagcagggca
    13921 ttcgtgtgat cctgccagat gcgatgaatc atggggagcg caaacagccg gtttcttcta
    13981 ttccatccta tacattttgg gatagtatct acggaaatct gtttgaattt gacacactta
    14041 tcaagcattt agaaaaaaga ggtcttctac atgatcagct tgcagttggc ggggtttcga
    14101 tggggggaat gacaacatgc gccttgttgg ctaaacatcc tcatatagta gcgggcgtgt
    14161 gtttgatggg ttcccctgca cctttggaat atggaaaaga aatcgtaagg cgcgcatcgg
    14221 aatataatta tgtcgtacca aaagactatt ttgatttgat ttcatgggtt aagagctatg
    14281 atttgtcatt gcagccggaa aagttagctg gacgtcctct gttcttttgg catggacaag
    14341 ctgacgaaaa aatcccttat atacaaacgg aacgatttgt agaaaaaaat cggcataagt
    14401 cttacggaaa agaaattgtt tttcgttcct caaaaacaca gcgacatatg gtacaaatac
    14461 cactaatgga agaagcttcc acttttttag caaaaaattt gataaaaaag tataaataat
    14521 tgaaacggaa aatcactcat gacgatagag gattttccgt tttttatttt gggctataat
    14581 aaactctgtt aggaaaattt ggtataattg atagtaagaa tgacaacatg ttagaaagga
    14641 agagagcatg cccactttag cagatgttgc aaaacgtgcc aatgtttcaa aaatgacggt
    14701 ctctcgagtc atcaatcatc cggaacaggt gactgacgaa ttgaaagagt tagttttctc
    14761 agcaatggct gaactggatt accgtccaaa tattgctgca aaagcacttg tcacgaatcg
    14821 gtcgcagatc atcaaattat ttatactgga agaaatcgac acaactgagc cctattacat
    14881 gaatttgctg atgggaatcg ctaaacggat cggtaaagcg cattattctc tccaattagt
    14941 tacaaatgat gccttcgacg tcggttcttg tgatggatac atcatcacag gtgtcagaaa
    15001 aaaagacttc gattggatcg accgtttgga aaaaccagtt gtcttgtttg gggaaaattc
    15061 tgaaggatat gattatgtag acagcgataa tgaatatggt acagcaaaag caacgcaata
    15121 tgccttagaa agagattatc aaacgattat ttatatcggt atcgaagtgg acgagccttt
    15181 tgaaatttca agggaaactg gttatttatc tgtgatgaag gaagttgatc ttcctagtaa
    15241 aatcttgcgg tttccaaatc attcgacaga agtagaaaga tatatgacag aaaactgggc
    15301 agattttaca gataaaactt gttttgtatg tagttcagat cggctagcac taggagcagt
    15361 aagagggatt ataaatgctg gaggacactt gcccgaagaa tttggtgtga ttggatttga
    15421 tggggtattt ttagaccaaa tcagttcacc taaattgaca acgatcaagc aagatattat
    15481 acgtatgggt gaagtatgtg gagaaatgtt gttaaaaaaa atagaagaaa aaggggcgag
    15541 tcaaggttat cgtcgttttt ttcctgaact agttatcaga gagacaacga attaagtctt
    15601 attactatat atatatttat gaaattcatc gctattttct taaaataatc agcgcattgc
    15661 tactgaaaac aatgaatctg tgctattatt gagaaaagtt ccatttttga gaaggatggt
    15721 ttgaatgaaa gaaatcagac gaaaacattt ccgttttcct gcgtacgatg atgagttagg
    15781 cgtaaaatta accaacgaca agaagcgagt attatttgac ggacaagaag atcttttgac
    15841 tgaacagaat cagtccccgt ttgaacagat gaaagaattt catttcacga acacgaacac
    15901 cgagaaaatc cgtcgcaagc gtcgtgcaac aaatggattg aagtcagctc cgcgtaagga
    15961 aaatttggaa aagcataaag gaaaattacc ggattatacc ggccattacc aatcagaaat
    16021 cacatcgaca ggacgaaaaa aactttttgg tgattcctct cgttctgtca gacaaagtga
    16081 aacaaggaca gagtccaagc atactacacg aaacgcatct gttgacacga aggtgcggga
    16141 gcgttcttat tttgttccta aatatgtacc cgcatcgatt atcccagacc ctagagaaag
    16201 caaaatttct gaggatcatt taatcgaatc gatgaaaaaa acggatgact cttatctgtt
    16261 gttcgataca gaaccgacgc cgtatcaaga aaaaagaaat ggtgagccgt ctgtacgaac
    16321 attcaatcga acaaaaacgt tagaggaaac aaagcagtca gaagaaaaaa aatcgaaaaa
    16381 aagccatggt atcttagaac gctcattaca aggattgatc gatgatcaag gaaactcttt
    16441 gggagaaaat agctatttta aataagtgat atacaaattt atattcggct acagttggaa
    16501 aggaaacgct gcggcgtttc cttattttat actctatccg aaagtttata tcgtatcctc
    16561 aaattttttt gagtttaagc gaattttttc tcccaataag taagaaaata atggcaaaat
    16621 aaaaaaacaa actattttcg cagatcgttt gcaaaaatag tttatttttt tataaagaag
    16681 attttactga ataatatcat tttagtttac ataatgatat ttctgtaaat taaataaagt
    16741 agtgaaaaat aagaatcagt gctctaactg ttcaagagga tcaagtggtt caaatgtttc
    16801 tgtagtctgt tttgcttcca attggggcaa aacagatcca atttccagat acttcacttt
    16861 attcaatgta taagatagaa tagaacagct aagtaatgta tacagaaaat gtgtgagatc
    16921 caaataaagc aaggagacaa ctaaaatacc aaaagtaatc aagaaaagac ttttgccaat
    16981 cttaatatga aaatattttt caatggcttg ataaatgata tctgttccgc ctgtgcttcc
    17041 gccgaatcga aagacgagac cgcaaccaat gccagaaaga atacctgtca tcaaactatt
    17101 gatcagtaga ctatctacag caaaatgtat atgaaggctc tcccataaat gtaaaaagaa
    17161 aactagcgca aatgttccga cgatcgtccg gagaaaagcg tgttttccaa aaagaaacaa
    17221 tgagataagc aataaaggta aattaaaaag cagtgaagtg acagaaggag cgaatccaaa
    17281 aagattatgc aaaagcaaag caataccagt aaccccacca tctgccagct tagatggaat
    17341 attgattcct gtcacagcta atccgtagat tcctgcgcct aaaatgattc cgcacaattc
    17401 tgtaaataaa tttaattttt tcatttctag cctcttttct tttgaaaatt ttcagcaact
    17461 tctttattat actgacttat actcttactt caagaggaaa atgaaaaaaa attatttttg
    17521 gctgtttctt tttatttatc aaataaggag tggaaaaatg cgagcagcag acttattgac
    17581 aattcttaca aaatcaccca aaaaaacaga gtatcaagga gtttttttgg ctcaagaaca
    17641 aaaactggtg cctgtgacaa tggtccagat aaataaagca aatcaattta tctttttatt
    17701 tgaacacggc aaagcaccac ttgctatgaa agacatcttt ctttttttga tgaagaaccg
    17761 tgagaaagct gtttattatc agtcaaaaga agaactcatt cctctttatg gagtgaaaga
    17821 gatagaaaat aaagtggtga tataagtaaa aataagaaaa caagacgttt atgatgtcaa
    17881 aacaaccatt ttttacattt ttggcaaaaa agtgtcatga tacagtataa tattcgttga
    17941 acaggccaat aaaggtgttc tcccccacga gatttctact ttattggctg tttcttttta
    18001 ttaaaataaa agttgtgtgt gtaaaaaaga tatagctgat tccaagtgac aatttcgtat
    18061 agatttttat ggtattcgta gtgaaaaaac gagaaccaaa aagttgatcc gactttgttg
    18121 cttggattct ttttttgtca gcatatttag aggtattttt ttcttttttt tgttcgtgct
    18181 gtaaggttaa ggcaagacaa gttagttggg aaaaaggaaa gaaatgttta tacttaaaga
    18241 ataacagaaa ggaaggtcgc atgaataatt ttatacaaac attaagtgaa agaaaaggcg
    18301 agttgctgga agctgcattt caacatctgt ccatttctct catttctttg ctgattgcag
    18361 cactgattgc tattccttta gcgatttggg cagccaatca taaaaaaatg gcagaagtct
    18421 tattgcagat cacgggtgtg ctccaaacga ttccttcact tgccttatta ggtttactta
    18481 tcccatttgt agggatcgga actgttccag cattgattgc acttgttatt tacgctttgc
    18541 ttccgatttt ccaaaacacg tatattggtc tagctgaaat tgacccgtct attgaagaag
    18601 cagcggtagc atttggtatg tccagaatga gacgcttgct gaaagtagag cttcccatcg
    18661 cattacctgt cattatctca ggtatccgaa ctgccttagt tttaatcatc ggtacggcta
    18721 ctttggcagc attgatcgga gcaggtggat tagggacatt tattttgtta ggtattgacc
    18781 gaaatacacc tgttttgaca ttgattggtg cgatcagttc tgccttgctt gcaattatat
    18841 tcagcggact gattcgctgg ttgcagcata agaaacctcg atattccatc attactttag
    18901 cagcagtggt gtgtttattt ggcggcgttt ctttatatca gtctgccttg tttaaaaatg
    18961 aaaccatcac gattgctgga aaattaggag cggaacctga aatcctgatc caaatgtata
    19021 aagaattgat tgaagacaac acaaaaacag aagttgaatt aaaaccgaat tttggcaaga
    19081 cgagtttttt gttcaatgca ctggatcaag gtcaaatcga tatctatcct gagttcacag
    19141 gtactgtcct agaaagcttg gtgaaggtac ctgaagcaat gaaaagtgct gatttgacaa
    19201 aagaaaaaac atatgacgaa gcagaagaat tattgaataa gcaattcgat atgacattat
    19261 taaaaccaat ggcttaccaa aatacgtatg ccttggcagt caagagatct tttgcgaacg
    19321 aacatcaact taaaaagatt tccgatttgg cagctatctc tgatcagatc aaagcgggat
    19381 tcacactgga atttattgat cgttcagatg gatataaagg aatccaagaa gcatatggct
    19441 tgaatttttc aagtgtacaa agcatggagc caagtttgcg ttaccaagca atcaataatg
    19501 gagatgtcaa tattgtggat gcctattcca cagatagcca gctcaaggag tacgatctag
    19561 tgactctaga agatgatcga gggttattcc cagcttatca aggcgcaccg ctgatgaaaa
    19621 aagattttgc taaagaacat cctgaaatcg ttaaagcact gaataaatta agcggaaaaa
    19681 taacagagga tcaaatgatt gatatgaatt accaagtcaa tgtcgaaaag aaaaagccga
    19741 cagaagtagc acgaatcttc ctgaaaaatg aaggattagt aaaggaggaa gatcagtgac
    19801 taaattaatc gagttcaaac atgtgcaaaa aaagtatgat ggaaagtatg tcatcgatga
    19861 cctaaatctg gcaatcaaaa aaggagaaat ctttgttttg gttggtcctt ccggtagtgg
    19921 aaaaacaact actttgaaaa tgatcaatgg attatctaaa ccatcagcag gagacatcta
    19981 cttcaaagga aaatcgttaa atgaatataa tctgcagaaa atgcggtgga atatgggata
    20041 tgtgctgcag caaatcgctt tgttcccgac catgacagtc aagcaaaata ttgaagtcat
    20101 ccctgaaatg ttaggttggg aaaagcagaa aagagcagac cgtgtagatg aacttcttca
    20161 aaaagttggc ttatctcctg atatttatcg agatcgtatg cctagagagt tgtctggagg
    20221 agaacagcaa cggatcggga tcatccgagc tattgctgca agcccagatg tgattttgat
    20281 ggacgagcca tttagcgcat tagatccgat ttcaagaaac tcattacaag aattggtttt
    20341 gtccttacac gaagaattgg gcacgaccat cgttttcgtt acgcacaata tggaagaagc
    20401 aatcaagcta ggtgatcgta ttgcatttat gaaggatgga gaaattatcc aatgtgacac
    20461 accagagcag ttattgatga atcctaaaaa cgactacgtt cggcatttct ttgatgaacc
    20521 gaaacagacg aaagagtggc gagtagaaga tttagtcgtc aatggatatt tcttaaatga
    20581 aataccagaa aatgctcgtc aacaagtttg ctttgatacg cctatgaaag aagtatattc
    20641 gcttctttcg gtgtatccaa gcattgtgat agtagaaaag caaagaagta ttgggtcgct
    20701 gacaagtaaa gaaatctttg cttttttaag tcgagaggag gaaggaaatg aaaacatatg
    20761 atgcaatcat catcggttca ggtgtgagcg gcttaagtgc tgcttatgga ttgaaagaag
    20821 caggtaaaac agtactagtg gtcgaagaag atctatgggg cgggacttgt cctaaccgtg
    20881 gatgtgatcc taaaaaagtc ttgttaagtg cagtagaggc acgtaatcgg gtaaaacaat
    20941 tgagtggaaa aggttttaac gagatcccaa ctgccaactg ggaagaactt caaaaattca
    21001 aacgaacatt tacggatcca gtcccagaaa gccgaaaaaa acaattagca gaagctgaaa
    21061 tcgatcatct ttcaggaacc gctcgttttt tggatgattc atctattgaa gtcaacgaag
    21121 aagtcttcca tgcggattac ttagttttgg caaccgggca aagacctacg atcttaccag
    21181 tggagggaaa ggaatacttg aaaactagtg cagacttttt atcattgcct gtactgccta
    21241 aagaaatcat ttttatcggt ggtggttata ttgcttttga gctagctacg attgccaatg
    21301 ctgcagggag caaagtaacc attgtccatc ataatcaacg gccattaaaa gaatttgagg
    21361 cgtctttggt agaggaagcc gtccatcaaa tggaagcatc tggcattcag tttgcttttg
    21421 gtgttgaaac ccaaaagatc atttcagaag gtactcgcta tcgtttagtc ggaaaagaga
    21481 cggaattagt agcagatatg attttttgtg cgactgggag acagccgaat acagaatctt
    21541 tagcacttga gcaagcgaat atcgtctttg ataaacacgg aattgcagtc aatgattatc
    21601 tgcaaacgag caatccaaaa atttttgcgt gtggagatat tgtttcaagg aaaaccccaa
    21661 aattgacacc agtcgccact tttgaaggaa attatgtagc taagcggata acggatgcaa
    21721 caagcgaacc tatcaaatat ccgattatac ctacgatcgt ctacgccagt cctaaacttg
    21781 ctgaagtagg agttacaaaa agtcacgcct cttcgtcaga tcaagtggta gagatggatc
    21841 ttaccagttg gttcacctat catcgtgtca atgaaccagt tgctaaggct gaattgacct
    21901 ttgaccagca aaattatttg attggtgctg cagtgattag cgagcaagca gacgaattga
    21961 tcgatgattt gacactcgtc atcaatcaaa aattgactaa aaaagagttg gatagctata
    22021 tcatggggta tccgacattg gcaagtgatc tctcctattt attgaaataa tcagcatgat
    22081 aactaaagcg cttgttgctt tttccttctt gtgctacact ttaaaaaatg aatacctgtt
    22141 tctggggatg tcgtagacga catgagagta agttgtgaac ttagacccat tgaacctgtc
    22201 agttaatact ggtgaaggga gaaacatagc agacgcttga agcgggttac tatgtcgtgc
    22261 ccatttcaag cgttttttgt tattcatatt agaagaaagg aggtaacaaa atgaagaaaa
    22321 atctttatcc agcagtcagt atggcattca ttttaattat ttggcagatt gttgtcatag
    22381 tttggaaaat acctgccttt attttacccg gacctgctgc tgtattttct gcattagcgg
    22441 cagatgcaca agtattactt tcccattctg tcacgacatt aaatgaagca gtgcttggtt
    22501 tggtaatagc tagcgttctt tcttttatta ctgccttggc aatggattat tggaagtttt
    22561 tagaaatgtc tttttatccg ttactagtga tttcacaaat gttgccaatc atggtgttag
    22621 ggccattact taccctatgg tttggtttcg gtatgcttcc aaaagtgatc cttgttgtct
    22681 tgataagcta ttttccgatc gtagtttctt tttcggatac attgaggaaa gtatcaaaag
    22741 agcaaatcat ctttttgaaa acgatggggg cagatacagg gaagatttat cgaatatata
    22801 aaataccagc gggtttatcc ggcttctttt ccggtttaaa agtggctgct acttattgtg
    22861 tcagcggagc agtcgttgga gaatggctaa gcgctcaagc aggcttaggg tattacatga
    22921 tacgcgtaaa aaacagctac cagatcgata aagtttttgc tgcgatcatt tgtgtcattc
    22981 tattgagttt attgctgaat ggcgcttgtt cattattgaa aaaagggtat tatcgtatgc
    23041 tttatatttt ttaagagaag gggatcaaat gaaaaaatta tggcttttat taccgctact
    23101 gttgctttta tccgcttgtg gcactgcaaa agaaacaagt agcaaacaag aaataaagga
    23161 tttgaaaaaa gtgacacttg ttttggatta tgtaccgaat actaatcata ctggcatcta
    23221 cctagcaaaa gaaaaaggct attataaaga ggctggttta aatgtccaaa tcatcgaacc
    23281 aggagataat tcgacaagta ttggtctagt aggtgcggac aaagcacaat ttggtgtaag
    23341 ttatcaagaa gatgtcactt atgctcacgc agatggacag aatataccag tcaaagcaat
    23401 tgctacagtg atcaaacata atacttctgg attcgccacc ctatcagaca gtaacatcca
    23461 ttcaccaaaa gattttgaag gaaaaacata tgcaggttgg caaagtccaa gtgaagaagc
    23521 tgtcttaaaa gctgtgatgg aaaaagacgg cggggacttt tcaaaactga caatggtagg
    23581 aagcaatgga gaagggccag aaagcttagg aaaatcctca gatatccaat ggtactttga
    23641 aggttgggat atgatcaaag caaaagaagc gggtattgaa ctaaactata tcccattgaa
    23701 agaattagat gaacggttag attactatac tccggtaatt attacgaatg atcaactgat
    23761 caaaagtgat ccagaattgg tacagtcttt tatggatgcc acgaaaaaag gctatcagga
    23821 agctattaag gatccaaatg acagtgctaa actgttgcaa aaatatgcaa aagaaaatga
    23881 tcggacgttt ttagaagaat cacaagcatt cttgtcaaaa aattatacgg atgatcctga
    23941 gaattgggga ttgatggaag aaaaagtttg gcgcaattat acagctttta tgcaggaaaa
    24001 cggattgatc aagcaagatg taccttcgca agaactattc actaatcagt ttataaaata
    24061 ggagtgatag atatgtcaat ccaaatcagc cacttgaatg tagtcattga aaacctgaaa
    24121 atattagaag acatccattt cactatccct aaagatacct ttacatcgat tgtcgcgcca
    24181 agcggagccg gtaagtcaac attgctgaaa actttaacag gagtccagcc tatgacttct
    24241 ggaacgatca aagtagacga tcaaaaagta actggtctcc atacagcatt tagttatatg
    24301 ccgcaagaag atatgttact tccttggctg agcgtctatc aaaacgttac gttatatcaa
    24361 aaaatcaatc atctaacaat caatgaagaa caagtaaggg attatctgga tatctttggg
    24421 ttaaacggct atgaacattt tttgccggaa caattatctg gcgggatgaa gcagcgaacg
    24481 gccttgttac gaacaatcat gaatccttct tcttacttgc ttcttgatga accatttgga
    24541 gcgttagatg ctatgaccag agggcagatg caagactgga tgttgaagct gcctaaaaaa
    24601 gcaaagcgga ctactttact tgtgacgcat gatatcgaag aagcaattta tttatcagac
    24661 aggattcttg tgctttccgc ccgtccggca catgtgattg ctgagattca agtgcctgaa
    24721 aaacgacggt cacgtgaatg gctactgcag caatcagagt tgaagcaaac gatttatcag
    24781 ttattggcag gtgaattaga tgttaagtga tgctcattgt catttagatg ggagtcagag
    24841 tttagcactc cttcagcagg aacacacgat tttgacgatc atcaattgtg attcgccaga
    24901 agaatggaag gaaaacagac agcttgcagc aagtaagact caagccttaa gttacggtat
    24961 ccatccttgg aaagcagata gctatacgtt tgaacaagtt gagccttttt tgaaaaaagc
    25021 aaggatcatc ggtgaaatag ggttagataa tatttggacg aatgtaccga tgactacaca
    25081 aaaaaaagta tttgagcgac agcttgcttt tgcagccata aatgagaaac ctgttgtact
    25141 gcacacaaaa ggatgcgaaa aagagatctt aaattatatc caagcttacc ctaatcacta
    25201 tttgatccat tggtattctt ctttggacta tcaacaagac tatattgatt taggctgtta
    25261 tttcagcatt ggtcttgatt tgaaaaagaa tccagcagtc tggcaactag ctaaagcagt
    25321 cccaatcgac cacttactta ttgaaacgga tggactacat gcagcagagt gggctttagg
    25381 ggggattttt tcagaaaaag attatgtctc actgcttgaa gaacagttaa agacaatcgc
    25441 tgagatcaaa gagctatcag ttgaagaagt taaaaaaaat acttatcaaa acttggaacg
    25501 tttcattaga ttaggtaaat aaaaaagaga tgtgacacaa ctagtgtcgc acctcttttt
    25561 ggctttcttt gtataaaagt aaactgtttg attaataaat gaatcttagt accaaccgtt
    25621 tgcttcccag aatgctttcg ccgcttccca agaaccataa cgtgaagtaa catattgttc
    25681 tgctactctt tcttggtttg cagcagagta gtcaccattt aagtaagaag aatctaattg
    25741 gtaacgtccg atgtaacgtc cgttcgttgc tgtgtaagaa ccgcttgatt ctttttgtgc
    25801 gatccattct tttgcagagc ttgtgcttgc tggagtagca gcagtttctg ttacagcagg
    25861 agcaggttgt gtttcagcaa caggcgctgc ttgtttttcc gtttgaaccg tttcttgtac
    25921 aacaggttgt tcagcttgga ctggtgcttc ttgaacggct gcttgaggtt cagcagctgc
    25981 ttgtgcagag ccttctgttg ggattgttaa ttgttgtcct gagta
//
LOCUS       DACDLM010000035        26019 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.035, whole genome shotgun sequence.
ACCESSION   DACDLM010000035 DACDLM010000000
VERSION     DACDLM010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26019
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.035"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(8..2389)
                     /locus_tag="IV356_001558"
     CDS             complement(8..2389)
                     /locus_tag="IV356_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAP9015249.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(2379..3026)
                     /gene="recU"
                     /locus_tag="IV356_001559"
     CDS             complement(2379..3026)
                     /gene="recU"
                     /locus_tag="IV356_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HAP9015250.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            3090..3629
                     /locus_tag="IV356_001560"
     CDS             3090..3629
                     /locus_tag="IV356_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HAP9015251.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWDEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            3719..4138
                     /gene="gpsB"
                     /locus_tag="IV356_001561"
     CDS             3719..4138
                     /gene="gpsB"
                     /locus_tag="IV356_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HAP9015252.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            4160..4527
                     /gene="rnpB"
                     /locus_tag="IV356_001562"
     ncRNA           4160..4527
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="IV356_001562"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            4736..5902
                     /locus_tag="IV356_001563"
     CDS             4736..5902
                     /locus_tag="IV356_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HAP9015253.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            5948..7444
                     /locus_tag="IV356_001564"
     CDS             5948..7444
                     /locus_tag="IV356_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HAP9015254.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMEDLYFNVYQVK"
     gene            7525..8208
                     /locus_tag="IV356_001565"
     CDS             7525..8208
                     /locus_tag="IV356_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP9015255.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            8853..10043
                     /locus_tag="IV356_001566"
     CDS             8853..10043
                     /locus_tag="IV356_001566"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HAP9015256.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKRM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLVTYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKAGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            10145..11098
                     /locus_tag="IV356_001567"
     CDS             10145..11098
                     /locus_tag="IV356_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HAP9015257.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWDLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDAMTKDMLEKLKEKLVETV"
     gene            11167..12516
                     /locus_tag="IV356_001568"
     CDS             11167..12516
                     /locus_tag="IV356_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP9015258.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETRGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(12698..13021)
                     /locus_tag="IV356_001569"
     CDS             complement(12698..13021)
                     /locus_tag="IV356_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015259.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPQALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            13150..14313
                     /locus_tag="IV356_001570"
     CDS             13150..14313
                     /locus_tag="IV356_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015260.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKLAFDSGTVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            14383..15732
                     /locus_tag="IV356_001571"
     CDS             14383..15732
                     /locus_tag="IV356_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAP9015261.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(15777..16208)
                     /locus_tag="IV356_001572"
     CDS             complement(15777..16208)
                     /locus_tag="IV356_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP9015262.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMEKSLA"
     gene            16596..19238
                     /gene="alaS"
                     /locus_tag="IV356_001573"
     CDS             16596..19238
                     /gene="alaS"
                     /locus_tag="IV356_001573"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HAP9015263.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDAPTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            19438..20034
                     /locus_tag="IV356_001574"
     CDS             19438..20034
                     /locus_tag="IV356_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP9015264.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            20156..21304
                     /locus_tag="IV356_001575"
     CDS             20156..21304
                     /locus_tag="IV356_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAP9015265.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFDDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(21342..21755)
                     /locus_tag="IV356_001576"
     CDS             complement(21342..21755)
                     /locus_tag="IV356_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HAP9015266.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            21834..22265
                     /locus_tag="IV356_001577"
     CDS             21834..22265
                     /locus_tag="IV356_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HAP9015267.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(22364..22597)
                     /locus_tag="IV356_001578"
     CDS             complement(22364..22597)
                     /locus_tag="IV356_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HAP9015268.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            22779..24449
                     /locus_tag="IV356_001579"
     CDS             22779..24449
                     /locus_tag="IV356_001579"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HAP9015269.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGIIAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNEWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            24614..>26019
                     /locus_tag="IV356_001580"
     CDS             24614..>26019
                     /locus_tag="IV356_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISEfa12 family transposase"
                     /protein_id="HAP9015270.1"
                     /translation="MMRKQSIEGRNQFAMLTIDDLVPKDHLVRKIDAAIQFDFIYPIV
                     ESTYSTHGRPSIDPVVLIKLVFIQYLFGIRSMRQTIKDVETNVAYRWFLGYSFEDPIP
                     HFSTFGKNYVRRFRETTLFEDIFSHILEQAVKAGFVTEDNLYIDSTHIKANANKHKFT
                     KEMTYGQAKAYQDELEDEINKERIAVGKRPFTWDTESELSLQKISHSDPESGYYVKGE
                     REKQFAYSAHTSCEDNGFILSTLITPGNVHDSQVAIDLVKQSKRAFPNIKRVVADAGY
                     KTPKFVHFLSHLKLYPILPYTVPHGVKGMFRKKDFVYDAYFDCYLCPNNQPLLFSTIT
                     RDGYRTYKSNPKFCRSCPLLKNCTLSTKHQKIVTRHVWADLMDELEHQRHTALNREIY
                     KKRKQTIERIFADAKEKHGMRWTKYRGLEKVATHTMLTFAAMNLKKLATWLWKAKKPM
                     AFYLKFLQRLTKRSWQLS"
BASE COUNT         8396 a         4583 c         5455 g         7585 t
ORIGIN      
        1 ttttttacta tctgtttcca gaagctgagg tgctgctgga tggtgtatgg tcatttgcag
       61 catccgctcc gctagttgct ggctcactgg aagaagcagg aggagcagat gaagacggtg
      121 tcgagctttc ttcggatgaa gaagaaggaa ccgttgttga agacgctggc tcgcttgttt
      181 ctgctgtcgt gctttctttt gaggactcag cagttgattc gctttgacta gtagagctag
      241 agctttgagt cgttgtctct gttgttgagc ttccaggagt ctggacatag ctggaagatg
      301 gaatagttgt tgatggtgta attgcattcg atctagctgt atattgatct ttgtagtaca
      361 gttcaccgcc cacacgaatt aatccgcttg gcatctccca gtctgtattt gtcacgttag
      421 ctgaaacata ctgcataagc tcgcgataaa catcagaggc tacgtgtgac gattctgaag
      481 tgacaggtgt cattttttta ttgtaacctg tccacacgga aatcgaataa tttggcgtat
      541 agcccgcaaa taggatatct ggatacaccc cagaagaaat accaagtttt gcatactcgt
      601 catctgtgta attggatgtt ccggtcttac cggcttgata taacccagcg atttgcgcat
      661 tcgtaccagt tccttcagtg atcgtatctt ttaaaatgtc tgtgatcata taagctgttt
      721 ctggagacat ggctgttttt ccatctggct cataagtttc ttctgttccg tcttggaaga
      781 cgattttatt aacatattga ggtttgtaat aagtccctcc attggcgaaa gccgcatagg
      841 ctgctgccat ttttaaggaa gaagctccgt attttgtccc atcttgttct tccgtattac
      901 tagagatcgc attcgattga tggatcgtac tgtattcgat cccaagattt tttaagaaag
      961 aagccacttt atctgaaccg acttcattga ataatttgac tgctggaaca ttacgggata
     1021 agtaaagtgc ttggcgtaaa gtaatggtgc ccatatattg attatcccag tttcctacag
     1081 gagtcgaagt cccttcatag ttatacggtg cgtcagtaat agtttttcca gtagaatatt
     1141 tcaaatattc aaaagctggt ccgtaatctg tgacaggttt catcgtagaa ccaaaatcac
     1201 gggaagtatt cactgctaag ttgttgccta aagttacgtc ttctgcgatg tgacgtccgc
     1261 caatctgggc ttttactttc ccggtattgg tgtcgataag ggtggaggca acttgcatct
     1321 cgtcgtctgg gtaagagaca tactgatccg tgttgacgat atcatatagt ttcttttggg
     1381 cgtccagatc caaattcgta taaatctcta aaccgtctgt gtagacattc ttatctgttt
     1441 tttcttgtac ttcattgatg acttctttga cataattatc gacgatctta gtattgtcat
     1501 cggattgagt tagttcttgc agaccatccg ttaccggtac attaacagct tgatcatatt
     1561 ctgtttgaga gattttttcg ttttgaagca tcgtatacaa aacagtatct cgtcttttct
     1621 tcgcctgatc tggataaaca taaggatcat aggcggaagg ggcttgaggc atcccagcaa
     1681 gcaatgctgt ttgcggtaaa gaaagttctg ataatttctt accaaagtac atctcagaag
     1741 ctgtctccat cccgtacaag ccgtttgaca tatacacttt atttacgtag taggtcaaga
     1801 tctcttgttt cgattttttt tgttccaatc ttacagccat ccacgcttct tgggccttgc
     1861 gtttcagggt ctgatcctcg gcactggtgg agaagaagga aagtttgatc aattgctgtg
     1921 tcaaagtact tccgccttgc agtccgccag aggtaaagtt agagagggca gaaccgatga
     1981 tccgaatagg gtcaaccccg atgtgtttat aaaaacggcg atcttctacc gacacgatcg
     2041 catcttctaa tgttttcggt aattcattcg cagaaatttt ttcacgcttt tctgcgccta
     2101 aatcttcgaa tagttcgcca tcttgtgtat atagtttgga agatacggta gcgtctaatt
     2161 ttttatccgt caattcgggc gcatcttttg cgtaatacca gaaaagtcct acacctgcta
     2221 aaaagaggat acagaaaaat gagagtattc ctaaaaggat cttgataaat aatccttttt
     2281 tatgtgttcc agaggacttt ccagaacctt tgccagaatt cttcttcaca ctctttttag
     2341 gagtaggctg tttctgtcgt ctagagcttc tagtttgttc atttgccatt cttgctttct
     2401 ccttcaatag ataatgttga taaatagaag tcaaccgcgt ccaaataagg aatccgcgga
     2461 gaaataccag ttttgatctc tattcctagt tcttcgatca aagataaagg tagtgatttg
     2521 cgtccttttt ccttttgggc gtcccagtaa gcaatcaaat gaacactatt caaataaaaa
     2581 cagcgcttca aagacgaaaa ccataacaag acaaagcaga ccccattttg ttcgaggcat
     2641 gctttcatat gttcgatttg atgggcatgg aagtttttaa agggaaaaga tgttttgttc
     2701 ttggtttctt ttgcttcaaa gtccaagtaa aagcctcgat agacgccatt atagtctgta
     2761 gttgaggctt gggtaaagta ggcttccttg atcacagcag cacttctctt aggatagtct
     2821 actttcacga tttggatagg ggtaggcttt ttatggataa ccgccaaccc gcgggaaaga
     2881 taatatttat tactttcatt gattgcttct tcaaagcgca tcccccgatt gccgaattca
     2941 gtgatctgat ttcttttttc ttgaattttt tcgacgggag aggcattctt ataataaggt
     3001 tggccatttg gatagcgcaa taccatcttt aatcacactc ctaggccaca ttatagcaaa
     3061 aaagcggata gaaagaaaag gaatctgaga tggataagtc aaaagtaatc tatgtgtctg
     3121 ggtatcgaag tttcgaactc ggtgttttta aagaaaatga tcctaaaatc caagttgtta
     3181 aaaatgtttt aaaaaaagaa ctccatcagt tagcagaaga agggctggaa tgggtacttg
     3241 tcagtgggaa tttgggcgtc gaactatggg ctgtgcaaat agtagcggaa ttgaaagaag
     3301 aatatccgga actatctctt ggtattttgt atcctttttc tgattttggt aataactggg
     3361 atgaagggaa ccaagaaaaa aaacaattag cagaacaatt agcagattat gtcgaagctg
     3421 ttagccatca accctaccaa tcacctagtc agctaaagaa tcacactcgt tttatacttg
     3481 agcatacagt gggctgtctg ctgatctatg atgaagaatt ccctggaaaa acgaagtatt
     3541 tttttgaaga tgcacagaat taccaagcag atcatcccta cgaaattcgg ctgatcagta
     3601 tggacgatct tcaaaatttt agtgaataat cgatattgtg tttgatttat caactttttt
     3661 cctatacaat gaaaaaggta gaaatgttat tacgtaaatg aaaactagag gtgtaaatat
     3721 ggcgaatttg gtttatagtc ctaaagacat tttacaacaa gaattcaaaa caaaaatgcg
     3781 cggctatgat cccgttgaag ttgatgaatt cttagacaat atcatcaaag attatgaaac
     3841 ttacagcaaa gaactccttg ctttacaaga agaaaacgat cgattgagtg caaaagtagc
     3901 tcaattatct aaaactcaag gagcagctca aacacgcgtg caacaaacag aggcaccaaa
     3961 gagcgcagca gtgaccaatt ttgatatctt aaaacgcttg tcaaatcttg aacgtgaagt
     4021 atttggtaaa aagcttgatc aacaagcaag tgcagtcaaa ccagcacaac ctaatccaaa
     4081 taactacaca aatgcagaca caagcttaga tgataatgaa aaaacacgtc aattttaatt
     4141 tttgattaat gaatttgcgg ttttcgggta atcgcggtct gacttgatca ggctgaggaa
     4201 agtccatgct cgcacaggct gtgatgcctg tagtgttcgt gcttagcgaa accataagct
     4261 aaggtactct ttggagtaac ggcaggaaaa caagctaagg cttcggctat gcttaagtat
     4321 ccttgaaagt gccacagtga cgaagcggct ggggaaaccc atccggtgga acgcggtaaa
     4381 cccctcgagc gagcaaccca aacaatggta ggggcgcttt ttgtctggaa gaagaacagg
     4441 acaaaaaggc agtataactg cagatagatg gttaccgctt tgttttttct ccctggaaaa
     4501 gcaaagtaca gaacatggct tatagaaaac cgcaaacatc agggaattag gtcgtgacaa
     4561 aagtaatgcg ttataagaaa caagaaaaac atttgaaagc tatttttcaa tacttcagat
     4621 gaatcgttct tattacaaaa caaacttttg tatcaccggt tattcggaat ttgagtaaaa
     4681 gtgtggggta ggactgatgt cccacctcct ttttttataa ataaggagat tgtgtatgga
     4741 aaaaaacagg aagttcaacc tcgtcgcaac tgcggcaagc gggctagaag cactggttgg
     4801 taaagaatta agagatcttg gaatcgaatg ccaagttgag aacggacgtg cacgttttga
     4861 aggaacaatg gaaacgatcg ctacagctaa tttatggtta cgtacagcag atcgagtaaa
     4921 aatcgtggtt ggggaattcg atgcgtatac gtttgatgaa ttgtttgaaa acgtaaaagc
     4981 attgccttgg gaagattttc ttccactaga tgcagctttt cctgtagctg gaaaatcgat
     5041 caagtcgaaa ctatatagca cacctgattg ccaagcgatc acaaaaaaag caatcgttga
     5101 acgtctccgt acctattatc accgtccagc ttctgtacca ctgacggaaa ctggcgcaca
     5161 ttttcagttg gaagtagctt tgctgaaaga ccatgtgatg gtaactctgg atacgacagg
     5221 accaagttta ttcaaacgtg gttatcgctt agaaaaaggt ggagcaccat tgaaagaaaa
     5281 catggcagca gcacttatta tgttgacaaa ttggcgaaaa gaccgtccat tttatgatcc
     5341 tgtatgtggt tcaggtacgc tttgtattga agcagcctta ataggccata atatcgcacc
     5401 aggattcaat cgtgagtttg cttgcgaatc ttgggattgg ttcagtcaag aaatcatgga
     5461 aaatgttcga tcagcagccg aagaaaaagc agattatgat attgaattag atattactgg
     5521 ttcagatatc aatggacgga tgattgaaat tgccaaagcc aatgcagaag aaatcggatt
     5581 aggctcttcg attaccttta agcaacaagc agtcaaagac ttcaaaacgg ataaagaata
     5641 cggggtcatc gtggctaatc cgccttacgg agaacgtcta ggagaagaag aaactgttcg
     5701 gaaattatat aaagaaatgg gcgatgtatt ccgtccatta aaaacatgga gtaaatatat
     5761 cttgactagc gacttagcgt ttgaggaatt ttacggacaa aaagcaacca aaaaaagaaa
     5821 attgtacaat ggtgcattgc gtacggatct attccagtat tggggaactc gtccgcctag
     5881 aaaaaaagag aaagacgaat aatcttacta attgattcat tcaattggat gtttggagga
     5941 atagggaatg aaagaaaaag agtttttaca agaagtaaaa gaaatcaatc ttctacaaca
     6001 agctttagga atccttgatt gggatacaca aacaggtatg cctgaaaaag ctagtgcata
     6061 ccgaagtgaa gtagacagct atctttacag catttatttt tcaaaaaaaa tcggtccaaa
     6121 aatcaaagaa gccattcgct atttttctga acatccggaa gaattgtcgg aagttggaac
     6181 tgccgttttt gccaaagtaa aagaagagta tgatttggaa catcgcgtac cggaagatct
     6241 tatgagaaaa tatacagctg ccgtttcttc agcacacgga caatggcaaa aagctagaga
     6301 aacacaacaa ttttctgatt ttcaacacgc attgaatcaa aatattgaat taacaaaaca
     6361 gttgatacct tactggagaa aagatgaaaa gacgaattat gatgttttgc tgaatcaata
     6421 cgaacccggg atgactgtcg aaatccttga taaggtattt gatcagctta aagaaggaat
     6481 tctttcgatc cgccgtacgc tccaagaaaa agggactgaa cctgaaacag actttttaaa
     6541 tcggagaatg acgaaaaaac aacagaagag atttgtagtg aaagtaatcg aacaacttgg
     6601 ttatgatttt agtcgtggtc gtttagatga cactgtccac ccatttatga ctggaattaa
     6661 tccgaatgat gcacgaatca cgacacgatg gaacgaaaca gatttcaaaa tggctgtttt
     6721 tggagtgatc cacgaggctg gtcatggtat gtatgaacaa gacatcgatg ataaatatgc
     6781 gtatacaccg gtttatgaag gtacatcaat gggtatccat gaatcacaat cgttgtttaa
     6841 cgagatcatt attggaagta gtcgcagctt ctggaaaaag caatatcctt tctttcaaga
     6901 atgtgcagaa ggaacattcg atgatattcc ttttgacaaa ttttatcgtt cattgaacca
     6961 tacaaaatca agtttggttc gtatcgaggc agacagtttg acttaccctc tccatatcat
     7021 cattcgttat gaaatcgaaa aaatgatttt caatgaaggg gtagatgttg ctgaactacc
     7081 tgaaatatgg aatcaaaaat atgaagagta tctgggaata cgaccaacaa atgatgtgga
     7141 aggcatccta caagacgttc attggtcagg tgcaagcttt ggttattttc cctcttatgc
     7201 attagggtac atgtatgcgg cacaattact tcattctttg cagcaagaaa tagatgtgga
     7261 aaatgttcta gcgtcagacg attattctcc aatcaaaaac tggatgtcag agcatatcca
     7321 tcaatatggt gcatctagaa aaccaaatca attaatcatg gatgcaacac atgaaccgct
     7381 taatccgcaa tacctgatcg actatatgga agacctgtat tttaatgtat atcaggtaaa
     7441 ataaaataca atttacaaag atagctgaaa ttcatctaat ctatagatgt tttcagctat
     7501 ttacttaaga aagaagtgga acgaatggat aaattacaag tgatcgctga ttatagtatg
     7561 gaccaattag cgcatgatca aacaggacat gggagcgatc ataccaaaag agttgtcaag
     7621 ttagctgaaa aaattttgga gacggaaccg caggcagacc gctttgtgac gcttgcagca
     7681 gcttacctac atgatacgat tgatgataaa gtcgttaaaa atgagaacga ggcaaagcaa
     7741 cagcttcgtg tattccttcg ctctttgcca atagtagagg aacagatctc gatgattttt
     7801 tccattatcg aaaatatgtc cttttctaaa aatctctctg aagcggccga actatctctg
     7861 gaaggtaaga tcgttcaaga cgctgatcgt atcgaagcat taggagcaat cggcattttg
     7921 cgtactgctt atttcggcgg tggacatggg cacccgattt ttgatcctga actgtatccg
     7981 caaacattca aggacaaaga aaattaccga aaaggcacga cagtgatcaa tcatttttat
     8041 gaaaaactgt tcttgctgtc tgataaaatg aatactgatt acggatatga agaagccaaa
     8101 cgaagagaaa ccttcatgcg tgaattctta gaagaatttt ttctggaatg gtctattgac
     8161 gatgaaaatt ttactccaga caattggatc aaaaataaca aaaaatgatg gaggttgtga
     8221 cagaagtggt cagctccaag atatttcgga tcattttccg taaaatttac ttctggaaca
     8281 ctgtttacca agaggtcatg agcctgccgt tcagctccga gtcacaagga acaatttcaa
     8341 aaaatagctt ctcatgtttg atgaatattg taacttgtga ttcggaattg gcaggagaac
     8401 accgtttatt cggaagaata ggactgtgac aagacttttg tcacagtcct tttttcgaat
     8461 tcaacaagta aaacttttaa gaaatattca gagagtaaaa ttaaaaattg ctgataaata
     8521 aagatggaag ttttatgtat ttttattggt ctatgcaata aataaattaa atattcagaa
     8581 tacaattgat tttaacgaaa gggcttctat caatggttgt gttgtattta tctgcccagg
     8641 tagagtaaaa tagatcatta tctaaaaggt aattgttcat actatataag tcatttgaaa
     8701 gtaaaaagat actgtaaata aaaaatgtgg ttaaataatt ctcataatca gtgtaagcgt
     8761 tatcaaaaat atggcatact tgctttgtag atgaatgaca cgatatatgt ttggtatgtt
     8821 ctgcaagaca gatgaatatg gaggtggaga caatgtcttc caaagaacta acaatgtatt
     8881 tagagaaaga attggatcaa ctgaaagaaa aggggttata caatacgatc gacatactag
     8941 aaagtgaaaa tggtgcttgt atcatcgtag acggaaaaag gatgatcaat ctagcatcca
     9001 acaattatct tggatttgcc aatcgcgaag aattgaaaaa agcatgtatt gaagcaaccg
     9061 aaacttatgg tgtaggagca ggagcagtcc gaacgatcaa tggttcgctg aaaatccatc
     9121 agcaattaga agaaaaaatc gcagaattca aagggacaga agcagcaatc gcctttcaat
     9181 ctggattcaa ctgcaatatg ggcgctatct ctgcagtaat gacaaaagaa gatgctatct
     9241 tatcggatga attaaaccat gcatctatta ttgacggttg ccgcttatcc ggagcaaaaa
     9301 tcatccgaat taaacatcaa gatatgaaag accttgagaa aaaagcaaag gaagcgatag
     9361 aaagtaagaa atataaaaaa atcatgtata tcacagatgg tgttttctcc atggatggag
     9421 acattgcacg attgccggaa attattccga ttgttgaaaa atatggactg gtcacctacg
     9481 ttgatgatgc gcacggctca ggcgtaactg gaaaaggtgc aggaaccgtc aagcattttg
     9541 gattaagcga caaaatcgat atgcaaatgg gcacgttatc gaaagctata ggtgttgttg
     9601 ggggttatgt agctggatcg aaaacactaa tcgactggtt gaaagctaga agtcggccat
     9661 tcctattttc tacttcgcta actccaggtg cagctgcagc tgcattggct tcgattactt
     9721 tgatgcaaga acatccggaa cttgtcgaaa aagtttggga aaatgctaat tattttaaag
     9781 aagaattgaa aaaagcaggc tataacatcg gtatgtctga aacacctatt actccagtca
     9841 ttttgggaga cgaaaaagtg actcagactt tctctaagaa gctgatcgaa catgggattt
     9901 atgctaaacc aatcgtttat ccaactgtgc ctcttgggac aggcaggatc agaaatatgc
     9961 cgactgcgga acatacgagg gaaatgcttg atgaagcagt agcagtttat caaaaaatag
    10021 gaaaagaaat ggaaattatt taactaaatt tagttttttc gtctatttaa aattagagaa
    10081 catgttcacg catatattgt taatcatctg aagatagtag taaaaaagat cagggaggat
    10141 catcatgaaa aaagtattgg tgacaggatg tttaggacaa attggttcag agttgatcac
    10201 acgactacgt caagaactag gcagtgaaaa tgtcattgcg acagatatac gcatgcctga
    10261 agtcattgag aaaaacgata tctttgagat cctagatgta atggattacg aaaaaatgcg
    10321 cagcatagca gaacaatatc aagtggacac attgattcat ttggctgctc ttttgtcagc
    10381 tgttgcagaa gcaaaaccac aattagcctg ggatttgaac gtgactgggc tggtcaatgc
    10441 attggaagtc gctagagaat tccagctgaa attttttacg ccaagttcaa tcggcgcgtt
    10501 tggtccaaat actccaaaag atcatacccc acaagatact cttcagcgtc ctacaaccat
    10561 gtatggggta acgaaggtag ctggagaact actatgtgat tattattatg tgaaatatgg
    10621 cgtagatact cgtggtgtcc gtttccctgg attgatttct tatgcaacct tgccaggagg
    10681 cggtacgaca gactacgcag tcgatattta ttattcagca atcaaagaag gaaagtacac
    10741 tagtttcatt gatcaaggta catcaatgga tatgatgtat atgccagatg cgatcgatgc
    10801 cattataaaa ctcatgaatg cagatcctga tcgattggtt catcgaaatg ccttcaatat
    10861 atcggcgatg tcttttgacc cggaagagat caaagcatct attcaaaaaa tcataccaga
    10921 ttttgaaatg gattatgatg tggatcctgt acgtcagtca atagcagaat cttggccaaa
    10981 ttcactagat gtttcttgtg cgcaagagga atggggcttt tcgccgaaat acgacttaga
    11041 tgcgatgaca aaggatatgt tggaaaaact gaaagaaaaa ttggtagaga cggtataaaa
    11101 caagaaccac atccaaaaag ttttttatac ttttgggatt ggctatggta tgaaagggga
    11161 caagggatgg aagaatatca agccacgcca gtaaaagaag taaaaataga aaatgaatta
    11221 aaacgtacga tgggattttt tactgcttta tcgactgtta tgggcacagt gatcggtgca
    11281 ggggtatttt ttaaagccgc aagcgtagca gaagttacag gatccgccag tttgcatatg
    11341 ttttcttggt ttctcggtgg tatgatttct gtctgtgcag gactaacagg agctgaactg
    11401 gcagctgcta ttccagaaac aagagggatg attaaatata tcgaacggat ttacggaaat
    11461 acagcagctt ttttattggg ctgggcgcaa gtcgtgattt attttccagc aaatgtagca
    11521 gccttgtcga tcattttcgg tacacagttc gtcaatctat ttggtctttc ccagtcaatg
    11581 attgttcccg tagctgttac agctgctgta tcgatcctgc tgatcaattt tttaggttct
    11641 aaagctggag gggcttttca gtcgattacg cttgtctgca agcttatccc tttgtttgtg
    11701 atcgtcattt tcggtttgtt ccgacaagaa ggagtagact tccaactgtt tccgatccaa
    11761 gcaggagaaa atctttcatt tttctcagcc ttgggagcgg gcttgctagc aacgatgttc
    11821 gcatacgacg gttggataca cgtaggaaat atttcgggag aattgaaaaa gccggcgaaa
    11881 gatttgccaa aagcaatttc tttaggaatc atcggaatca tgatcgttta tttattagta
    11941 aatgcggtgt tcttaagaac cgcatctatc gacggagtcg caggaaacag caatgcggca
    12001 agtgacgttg caaaaatgat ttttggcggc ttcggtggaa gactggtcac agttggtatc
    12061 ttgatttctg tttatggaac catcaatggc tataccctta ctggaatgcg tctcccttat
    12121 gttatggcaa aagaaaacaa cctgcctttt agcaagctct ttgctaaact tcatgataaa
    12181 actaaagttc ctgtagccgc aggtatctta gagctagtca tcgctattgg catgatgatg
    12241 atcggtggtt ttgatacact aacggatatg ctgatctttg tcatttggat tttttatacg
    12301 atggtctttg ttggtgtcat tcttcttcgt aaaaaagaac ctgatttgtt tcgaccatac
    12361 aaagttccaa tgtatccgtt tattccacta gtagcaatca ttggagggac ttttatcgta
    12421 tcaagcacgc ttatcactca gaccttttta gcttcgatgg ggatagtatt gacacttgcc
    12481 ggtatcccga tttatctcta tttaaaacgt agatagctaa aacattcgaa ttttattaga
    12541 actgcactct ctgccaaaca aaatatttta tttaaatgag gagtacgtgg aagaaatgtc
    12601 aaaagtactc gttaattttg atcacgtaaa tgtcgttttg tctacaatga aatagcaaag
    12661 taaaagacag aaatcgggct caaccgattt ctgcctttta ctttgatttg cgtaactgaa
    12721 ctattcggcg tacgccgcga taaatattta ataaaaccaa gcaaccagaa atgaaaatgg
    12781 gaagccaaat cagatagaca gggtagccaa gcactttaga caaagcttgt ggagtcattt
    12841 tatccatttc aagaagtgct tgctgccaag tctgaagatt gaagactagc atgaaacccg
    12901 aaataatcag gagaataaat cctaaataat gaattgtagt tctttttctt acataagcga
    12961 tcgtagcata aaggaacagt aaaaaaatag gtacgccaaa aacaaagtac atattcagca
    13021 tctcgacacc ccctttgtgt ttatcttact ttactttgaa agaaatgaga aataatagcc
    13081 tcgttacttg cttgaaacag caaaggactg ctaagataag agagatacaa agaatcaagg
    13141 aggagtcata tggcaagtta tatcgaaccg attcgttttg cgctgattgt ttttccattt
    13201 ttagccttag cgatctcatc tgtttttttt atttatgaat atcgaaagta tggaacattt
    13261 ctagtaacaa gggcagttat tttgtattct ttcgtttttt atttattgtg tgcgtatttt
    13321 ttggtgatct taccacttcc ggcaaaggag acggttgccc aaatgactgg gccaaagatg
    13381 gagctgcatt tatttgcttc atggcaacat ttcagagaca acacggtatt ggtcttgtct
    13441 gaacctagta cctacctgcc ggcaatgaag cagagtgtat ttttggaacc agcttttaat
    13501 gttttattac tcataccatt tggcatttat ttaagatatt atttccggct ttcttttatg
    13561 aaaacgatga ttgctagttt ctgcctttct ctattttttg aattgacgca gctaagtgga
    13621 ctttatttta tctacccaag accataccgc ttatttgatg tgaatgattt agtgacaaat
    13681 acattgggtg gaatcattgg ttttgtcgtt acgccgttat ttacatttat gcttcctaca
    13741 agaagacgaa tggatgaact ttcttatgaa aaaggaaaga ctgtctcatt gactcgacgc
    13801 ttggtcgctt atttgatcga ctggacattt ttatctctta ttaatttggt agcggcgatt
    13861 ttctttaaac ttgcgttcga ttcagggaca gttacttctc atatctggtg gcttttatta
    13921 gaagtagggg tatactttat gattgtaccg tttataacca atggatggac acttggcaaa
    13981 aaaattgtgc gtatccgttt ggtggaagaa gaccgcgaac gaatttcttt aaaagcattg
    14041 atgatccgct acgggtatct gtactttctt ttttatggtt taagctggtt ggggcagttg
    14101 cttcagcaaa tcatgaattc gacaacgaat acggtgttgc agatgagtgc agtattcatt
    14161 tctctcggtg tcttgttact gcaaggtatt tttattttaa atatcttgct atcatttttg
    14221 agaaaaaaac ggattctgtt ttatgaaaaa gctagtcaca catatactgt tagcacgatt
    14281 ggccaaacaa aggatgatga ttctcgaaat tagctgagca aaaacccttt gtctgtgtta
    14341 taatgccaaa gtcgtgataa tttaaagaga agaggtgcac gaatgaataa ttttgatata
    14401 ttccgcttca aaccgtttat caatgaagcg ttaaccgcaa agggcttcaa acagcccaca
    14461 gaggtccagg aacgtttgat tcctttaatt gcaaaaggaa aaaatatcat tgggcaatct
    14521 caaactggta caggaaaaac acatacgttt ttgttgcctt tgtttgaaaa aatcaatgca
    14581 gaaaaagagg aagtacaagt tgttattaca gctccaagta gggaactagc tgcacagatc
    14641 tatgaagcag ctacacaaat cgctaaattt tctacaccgg agatccgtgt ctcgaatttt
    14701 gtcggcggta cagacaaaca gcgtcaatta aatcgtctgc atcaccaaca gccacaggtc
    14761 gtagtaggca cgcctggtag aatattagac atgatgaatg aacaagcgct gaagattcac
    14821 accgcatttg catttgttgt cgatgaagcg gatatgacat tggatatggg ttttttaaat
    14881 gaagtagacc aaattgcaag tcgattacca gaaaagctgc agtttttagt tttttctgcc
    14941 actattccag aaaaacttcg tccattctta cgaaaataca tggaaaatcc aatcattgaa
    15001 gaaatcaaac caaaagcagt tatttctgaa gacattgaaa attggctgat ttcaacaaaa
    15061 ggtaaagatg agaatcaaat gatttatcaa ctgctgacaa ttggtcatcc ttatttagca
    15121 atcgtatttg ccaatacaaa acagcatgtg gatgaaattg ccgattactt gaaaaaccaa
    15181 ggcttgaaag tagcaaagat tcatggagac atcaccccaa gagagagaaa acgagtgatg
    15241 cgacaagtac agaatctgga gtatcaatat gttgtagcga ctgatttagc tgctagaggg
    15301 atcgatatcg aaggtgtttc tcatgttatc aatgcagaaa ttccagaaga tctagacttc
    15361 tttatccatc gtgtcggacg tactggacgt aatggcttaa aaggaacggc cattacgtta
    15421 tattcgccaa atgatgagca agccattgat gcgatagaaa aattgggcgt ctcatttgaa
    15481 ccaaaagaaa tcaaaaacgg ggaaatcgtc aaaacatacg atcgtaatag acgtgccaaa
    15541 cgagaaaaat caaaagatgt attagatccc acgctgattg gtcttgtgaa gaagaaaaag
    15601 aaaaagatca agcctggtta taagaaaaaa atcgattggg caattgcaga aaaaaataaa
    15661 aaagaacgca aaatcgaacg cagacagcaa agccgtactg ctcgtaaaaa taagaaaaat
    15721 tcacataaat aaaaaacaag aggttgtgac aaaaggcgtg tcacaatctc ttgtttttaa
    15781 gctagacttt tttccattcc gatacaaagt acttcatctt caataaaagg ttctgtgcaa
    15841 gtatgatacc cttgtttttc ataaaaatct acagccgtca tttcagctac tacataacta
    15901 gtctgacaac cttctgaaac cgcccgtttt tcagcagctt caagcaactg accgcctaac
    15961 ccttttcctc ggtattcttt tgctacgcaa aatcgttccg gcttgaagca agtaggtgtt
    16021 ttcttttcat aacgcaaagt agctactggt cttttttgat caagaaatag ataataggtt
    16081 tgttgcggga tatcttttcc gtcgaattct agttctgcag gaatcccttg ttctaataca
    16141 aaaacttgat atctcaaaaa gcagctagct gcgcgtatcc attcatccgc tccaactatt
    16201 tttttcatca tattcctcct tgtcatgaat agcagagatg tattgattcc tttattctta
    16261 tcgtaccaaa aatcgtggag tatgaccaaa aggaaatgaa aataaaaatt gagatattga
    16321 cagtgatcaa tagaatgcgt atactaatta agtacgaaaa ggatatgatt tgttttttaa
    16381 gactcacaga aaattctttc ttggctgaaa aaagaatagt cactaatcaa attgctccct
    16441 ttttctattt tggtagaaat accgacgcag ctcagcgtta tcgagtttaa gaggtaatga
    16501 ttacacatca ttgcaatcaa ggtggtaccg cgagttttcg tccttggctg tgatggtgtt
    16561 tttttgtatt taatttatag aaagcaggta atgacatgaa acaattaagt agtgcacaag
    16621 ttcgacaaat gtttcttgat ttcttccaat ctaaaggaca tacgattgaa cctagtgcgt
    16681 ctttgatccc cgtgaacgat ccaaccttat tgtggatcaa ctctggtgtt gcaacattga
    16741 aaaaatattt tgatggttca gttgtgccag aaaatccaag aatcacaaat gcccaaaaat
    16801 ctattcgaac aaatgatatc gaaaatgtcg gtaaaacagc acggcaccat acgatgtttg
    16861 agatgctggg taatttttcg attggtgact atttcaaaaa tgaagccatc cactgggcat
    16921 gggaattttt gactgatcca aaatggatgg cattcgatcc agaaaaactt tatgtaacag
    16981 tttatccaaa agatacagaa gcaaaacgca tctggcatga agaagttggc ctgccactag
    17041 atcacattat tgatgtagaa gacaacttct gggatatcgg tgcaggccca tgtggtccgg
    17101 atacggaaat tttctatgac cgtggagaag cttataacga tttagcagaa gacgatcctg
    17161 aaaactatcc aggaggagaa aatgaacgtt atttagaaat ctggaactta gtattttcag
    17221 aattcaacca taagcctgat aacacatttg aaccacttcc tcataaaaac attgatacgg
    17281 ggatgggatt ggaacgcatg gtctcaatcg ttcaagatgc gccaacgaac tttgagacag
    17341 acttgtttat gcctattatc cacgccgtag aaaagctaag caaacaagta aaatatggtg
    17401 aaaacccagt aacagatatt tcttacaaag taatcgcaga tcatattcgc gccctttcat
    17461 ttgctattgg cgacggtgca ttgccatcga atgaagggag agggtatgtc ttacgccgtt
    17521 tgcttcgtcg tgctgtcatg catgggaaaa aattaggtat tgaacaagca ttcttatatc
    17581 gtttagtccc tgttgttggg gaaatcatgg taagttatta tcctgaagta cttcaacaaa
    17641 aagaatttat tgaaaaagtt atccgtacag aagaagaacg tttcaatgaa acaatcaatg
    17701 aaggtttgga aatcttaaat caagtgatcc aagaagtaaa aaacgaaaac gggacgactc
    17761 tagcaggaaa agacatcttc aaactatacg acacatatgg cttcccggta gaattaacgg
    17821 aagaggtggc agaagatgaa ggactgaaag ttgatcatgc tggttttgaa aaagaaatgg
    17881 atgcacaacg cgaacgtgct cgctctgccc gcagtactga aaaatcaatg ggggtacaat
    17941 ctgctttatt gacagatatc aaagtagaaa gtaaattcat tggatacaca gaacaagaat
    18001 cagatagtca attattggtc atcgttaaag gtgagtctct tttgaatgaa gtcgcagaag
    18061 gtgaagctca aatgatcttt gatcaaacac ctttctatgc agaaatgggt gggcaagtag
    18121 cggatcaagg atggatcatg aatgaagtag gcgaaatcgt agcagttgtt acagatgttc
    18181 aaaaagcgcc taatggtcaa tttatgcaca ccgtagaagt aaaagcacca atgagtgaag
    18241 gacaaaccta tcatctattg attgatcaat cgatgcgcaa tcggatcatc aaaaaccata
    18301 cagcaaccca tctactgcac aaggcattga aagaagtact tggcgagcat gcaaatcaag
    18361 ctggttcttt agtcgctcct ggacatttac gattcgactt tacccacttt ggtcaaatca
    18421 cttcagatga attagctgaa atggaaagaa tcgtcaacga aaaaatctgg gaagctatcc
    18481 cagttgaaac aattgaaaca gatatcgata cagccaaaaa catgggtgca atggctttgt
    18541 ttggtgaaaa atacggacat gacgttcgag tagtaaatat tggcggctgg tcaatcgaac
    18601 tgtgcggagg cacacatgta gcaaatacag aaaacatcgg aatcttcaaa atcgtttctg
    18661 aatcaggaat tggtgcaggc gtgcgacgaa tcgaggctgt aacaagtaaa gaagcgtacg
    18721 aactacttga agaagaagaa aaacaactaa aacaagtagc aacaattgtt aaatcacctc
    18781 aattgaagga agttgtttca aaagcggaac aattgcaaca gcaagtaaga gagctacaaa
    18841 aggaaaatga acaattagct agcaagttag cgaatcaaca agctggtgat gtattcaaag
    18901 atccagaaac gatcaatgga aaaacaatca ttgcagcaca agtaaaagtg aaagatatga
    18961 atcagctgcg tcaattagct gaccaatgga aacaaaaaaa tatttcagat attcttgttt
    19021 tagcaaacga acaagaagga aaagtcagtc tgctagcggc aatgacgaaa gaatcaaatg
    19081 aagctggact aaaagctggc gacttgatta aagcaatcgc accgaaagta ggcggtggcg
    19141 gtggtggacg tccagacatg gcacaagctg gcgggaaaaa tcctgctggt attccagatg
    19201 cacttaaagc tgcgaaagaa tgggttgcgc aacaataggg cgtttacgtt tgacagaaaa
    19261 acaaaagttc aaacattgaa cgaaacatga ttatgggggc gaagacaaac aagtcttgcc
    19321 ctcatacttt tttcaattgg ctggcgcatc taatcaaatg gtcggattcg gatggtcttt
    19381 agttgacgaa agtgacagaa atttttacga ttagtataaa taaaaagggg tgaaaaaatg
    19441 aatagtagaa ataagacctt tcgactagtc ttacgtgcga tcttgttagc aatcatcatc
    19501 gtacaagcga tggttccttg gctggggttt attccattag gattcattag tttaacaatt
    19561 atccatatca cagtaattat tgctgcagta gtattaggcc caaaagatgg catggtgatt
    19621 ggcttgtttt ggggaatcgc tacaattgtt cgtgcctatg ccatgccaac aacgccattt
    19681 gatacattag tgttcacgaa tccgattatc tcggtagttc ccagagtact tgttggctta
    19741 gtagcaggct tggttttcca ctggatttat caaaaaaata aatcaataac gatcagctca
    19801 gcctttgcag gggtactggg ttcattggtc aatacagtct tagtgttagg attcatggga
    19861 ttattttata caggtgcaac ggcagatgcc tatggtgtag attctgctct tttatttaaa
    19921 accttagcag gggttgcagc aatcaatggg ataccagaag caataggtgc gggaatcata
    19981 acaccattac tagcaaaagc gttatttgca gcaacaccgt tgaaaccaga ataatgacca
    20041 tcttttaata gtaataggac gcacgataga tagaaaaagg aagagaggag aggaaaacaa
    20101 tcgtcctctc catcttttta cctgagcaac aagcaaacta gaaggggtaa aaaacttggc
    20161 taagaaacaa gaagaaaaaa agaaacaaat accgcaacag cggacaaaaa aaggagtact
    20221 agcgggtatc ttaggattgg ttacgaatct gatcttgttt gtctctaagc taatgatcgg
    20281 gcttttttca ggaagtgtct ccattatggc tgatgcagtg aacagtctat cagatactgc
    20341 ttcatccata ttgactttga tcggatttaa aattgctgca aagccagcag atcaggaaca
    20401 tccttatgga cacgaacgct tcgaatatat cagtgggtta tttgtttcga tcatcattac
    20461 ttatgtagga tttcaatttt tagagtcttc tgctgaaaaa atcatccatc cagaaaatgt
    20521 ctctttaaca cccatcgtct tttttgtcct aatcatttcc atctttttga aatttgcaca
    20581 aggcaaaatg tatcaggtta ttgcgcaatc cattgattct gaaacattga gagctacagc
    20641 aacagatagt tataatgatg tctttactac actggctgta ttgctttcag cagcaatcga
    20701 atgggtaact ggatggcgta tcgatggata tataggtttt gctttagcat tatatatcct
    20761 ttatagtgga ttgacgatgc ttcgaaattt tgtatacgaa ctattaggaa gtcgcccaac
    20821 gccagcagag attgaagaaa tggaagagca tttaaatgct tgcgatgata tacttggcta
    20881 tcatgattta ttggtgcata actatggacc caataaacgc tttgcatcag tccacatcga
    20941 agtagatgaa tcaatgaatt tgaatgtggc tcataagatt attgatctga tagaaaaaga
    21001 ctttaaaaag tctttggatg tggaacttgt ctgtcacttg gatccaatgc ctgttgataa
    21061 cgaaaaatac tataatatct tgcggcagtt aaagcaaatt cttcttgaaa caggtacagg
    21121 gcttaatatt catgatttta gagtaattca tcaaggaaaa acgctgcaat ttgatgtagt
    21181 ggtccctgag aaattccagt ttgatgatac agaactagaa agaatcttac gtagtcaaat
    21241 agaagaaaaa atcggagatt accaattgga aattacgttt gatcacaatt atcttttata
    21301 ttaaatgaga aactataaaa agactcctta aagtttttaa tttaaagagt ctttttttct
    21361 tttaattgtt tatggagagc ctgacgtgca agattatctg ctcctttatt tttgttttcg
    21421 ggcaaccatt gcaggatcaa taaagaaaat tcggatagaa gttcttggat tctttgaagg
    21481 tagggaagga agagctcgtt cttcgttgcg tttttgtcga ccgtagaaac tagtgttttg
    21541 ctgtctgaaa aacagaaaat cgtttcattc tgtaagtcgt ttttctttag aaattctaaa
    21601 gtttttaaaa agacttcgaa ctctgcttga tggtttgtcc ctatagaaag cgggatagat
    21661 agctgttctt gtttaccttg atagacaatc aagattccgc ctccactagg accagggttg
    21721 ccttttgtag aggcatcaat gtatactttt aacataaaaa gagattctcc tttttgttca
    21781 aactaatgtt atggtaagat tatatcatta ctgaatcggt gagaggttag agaatgaaaa
    21841 aaaatattcg atggcagcct gaactggcac atacgatcat ctattggtca ttgaccttga
    21901 tcattctgtt ttttagtctg attctttctt tagaaaacac aggtccttat tggaaaagca
    21961 attttgtttt aggtattttt cttgtttttc tatttctagg tttgcgacgt tcttttattt
    22021 taaaatcaaa ctctgtgatt atacgttatg ctgctttttg gaaagaccga gaaatatctg
    22081 tcggacagat tcgatctttg acgccaacta atactggggt gcaaatgatg ttgcaagatg
    22141 agaaagcccc atctgttttc atgatgcgaa aaaaagatca agtagtcctt tttgatcatt
    22201 ttgaaaaaaa cggacccaaa tcagaatcaa ttccttatcc ttatacgaaa aaaagaaaaa
    22261 gctaatttta aaaatcagaa cctaaaaaaa cgaattttta caggaaaaga aaagagtgag
    22321 acgtacggtt catcccgttt agcgtctcac tctatttgtt tatctattca tgcatactag
    22381 tatcggtagt ctgaacgttg cctttcttga catgggcagc ttgtgttcct cgattccctt
    22441 cgatgatctc aaattcgacc acttgatttt cttccaaagt tttgaatccc tcttcttcaa
    22501 tcgcagtaaa atgtacaaaa atttcttctg tgtcatcata actgataaag ccgtatcctt
    22561 ttttgttgtc aaaccatttt acaattcctg tggtcaaagc actcacgacc tttctaaagt
    22621 ctgatcatag ccttcattat aaagagtatt tataagtacg tcaaataaat taaaaacctg
    22681 taattttatg ttttttttat tataaaaaaa ggtataattg gcatatctta acaaagaaga
    22741 tattttgttg aataaagttc gtgaaaaggg gtaatcaaat gaagaatgat ctgcaaattt
    22801 cacaagaaac agagctagaa ccgattgttg aagtggctag taaattagat cttaaggaag
    22861 acgatttgga actgtatggg aaatataagg cgaaaatcaa tttttctgga atcaatcgat
    22921 caaaggataa cgctgagggg catttgatct tagttacttc catcaatcca acaccagctg
    22981 gcgaaggaaa gtcaacgatc actgtagggt taggagacgc gctcaataaa atcaataaaa
    23041 aatctgttat tgcattgcga gaaccctcac ttggtcctgt gatgggaatc aaaggtggtg
    23101 ctgcaggcgg aggatatgca caggtattgc ctatggaaga tatcaacttg cattttactg
    23161 gtgacatgca tgctatcaca acagctaata atgcattatc tgctctttta gataatcata
    23221 ttcatcaagg aaatgaattg aacatcgatg cccgccgagt gatttggaaa cgggtagtcg
    23281 atctcaatga tcgtgaactg cgtaaagtaa ttgttggctt gggtgggcca atccaaggtg
    23341 ttccaagaga agatgggttt gatatcacag ttgccagcga aatcatggct atcttgtgtc
    23401 ttgcggcaga ccttgaagat ttaaaggctc gtcttgcaag gatcgttgtc ggctatacat
    23461 ttgaccgtca gcctgtgact gctggagact tgaaagcaga aggcgctctg gcattactgc
    23521 tgaaagatgc aatcaagccg aatcttgtac aaacaattta cggaacacca gcttttgtcc
    23581 acgggggacc gtttgccaat atcgctcatg gctgcaatag tattttagct accaagacag
    23641 cattgagatt agcagattac gttgtcacag aggcaggatt tggtgcagat cttggcggag
    23701 agaaattttt agatatcaaa gtacctaact tgaaaaaagc gccggatgct gtggtgattg
    23761 tcgccactgt ccgtgcattg aaaatgcatg gcggaatgaa aaaagatgaa cttaaaaatg
    23821 agaatcttga tgctttgaaa gtaggttttg caaatttaaa gcgccatata cgtaatatgg
    23881 aacaatatca gctacctgtg atcgtcgcaa tcaatgaatt cgtaacagat acagacaatg
    23941 aactcacact gttggagcac ttgtgtgaaa atcaggggat tattgccaag agagcgagtg
    24001 tatgggcaga tggagcagaa ggcggcgttg atttagcaaa agctgtagta cgattgattg
    24061 atagaaaaga agctaattac aagccattat accgcctaga agaaacgata caagaaaaga
    24121 cagaaacaat cgtcaagaaa atttacggag gaaatggtgt tgttttcagc aaaaaagcgc
    24181 aaaaacaaat agaagagttt acgaagaatg aatgggacaa actgccgatt tgtatggcaa
    24241 aaacacagta ttcattttct gatgatcctt cactgctagg tgcaccggaa gatttcacca
    24301 tcacgatccg cgaaatcatc ccaaaattag gggcaggatt tttagtagcc ttgactggag
    24361 atgttatgac gatgcctggt ttgcctaaaa aacctgctgc attgaatatg gacgtgacaa
    24421 atgacggaga agtgttggga ttgttttaag cttgattata atctaccgta tactaaataa
    24481 ctttcattaa acatcgaagg agctgtattt tgactacagc ttccagactg tagacaaact
    24541 cctaaattgg gagtgttgtt tgcagttttt ttgttttata ctcattgtat aaactattct
    24601 gggagtgatt ctaatgatga gaaaacaatc gattgaaggt agaaatcaat ttgctatgtt
    24661 aacaattgat gatcttgtac ctaaagatca cttagttcga aagattgatg ctgcgattca
    24721 gtttgatttc atttatccca ttgtagaatc tacgtattcg acccatggtc gtcccagtat
    24781 tgatccagtg gtcttaatta aattagtatt tatccaatat ttatttggta tccgttcgat
    24841 gagacagact attaaagacg ttgaaacaaa tgttgcttat cgttggtttt taggttattc
    24901 attcgaggat cctatcccgc atttctctac ttttggtaaa aactatgttc gaagattcag
    24961 agaaacaact ttatttgaag acattttctc tcatattcta gaacaagctg taaaagctgg
    25021 cttcgttacg gaagacaacc tttatattga ttctactcat attaaggcaa atgccaataa
    25081 acataagttc acaaaagaaa tgacctacgg tcaagctaaa gcttatcaag atgaattaga
    25141 agatgaaata aataaagaac gtattgctgt aggaaaacgt ccttttacat gggacacaga
    25201 aagtgagttg agtcttcaaa aaataagtca ttcagatcca gaaagtggtt actatgttaa
    25261 aggtgaacga gaaaaacaat ttgcttattc cgcgcatact tcctgtgaag ataatggttt
    25321 tatcttatct acattaatca caccaggaaa tgtacatgac agccaagtcg caatcgatct
    25381 ggtcaaacag tcgaaaagag cttttccaaa tataaagcgt gttgtcgctg atgcaggata
    25441 taagacgcct aaatttgttc attttctgtc acacttgaaa ctctacccga ttcttccata
    25501 tactgtacct catggagtaa aaggaatgtt tcgtaaaaaa gactttgttt atgatgccta
    25561 ttttgactgc tatttatgtc ccaataatca accgttgtta ttttcaacta tcactcgtga
    25621 tggttatcga acctataaat caaatccaaa attctgtagg agttgtccat tacttaaaaa
    25681 ctgtactttg agtacaaaac atcaaaaaat agtaactcga catgtttggg cggatcttat
    25741 ggatgaactt gaacaccaac gccatacggc gttgaataga gaaatttata aaaagagaaa
    25801 acaaaccatt gaacgaatat ttgcagatgc aaaagaaaag catggtatgc gttggacgaa
    25861 atatcgaggt ctcgaaaaag tcgccacgca cacgatgctt acgtttgctg ccatgaattt
    25921 aaaaaaacta gccacatggc tatggaaagc aaaaaagcct atggcttttt atttaaaatt
    25981 tctacaaaga ctaacaaaaa ggagttggca attaagcca
//
LOCUS       DACDLM010000036        25671 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.036, whole genome shotgun sequence.
ACCESSION   DACDLM010000036 DACDLM010000000
VERSION     DACDLM010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25671
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.036"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            170..514
                     /locus_tag="IV356_001581"
     CDS             170..514
                     /locus_tag="IV356_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HAP9015271.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            515..934
                     /locus_tag="IV356_001582"
     CDS             515..934
                     /locus_tag="IV356_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HAP9015272.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1026..1376)
                     /locus_tag="IV356_001583"
     CDS             complement(1026..1376)
                     /locus_tag="IV356_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015273.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1342..2673)
                     /locus_tag="IV356_001584"
     CDS             complement(1342..2673)
                     /locus_tag="IV356_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HAP9015274.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2929..3495
                     /locus_tag="IV356_001585"
     CDS             2929..3495
                     /locus_tag="IV356_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP9015275.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3640..3727
                     /locus_tag="IV356_001586"
     tRNA            3640..3727
                     /locus_tag="IV356_001586"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3672..3674,aa:Ser,seq:cga)
     gene            4061..5035
                     /locus_tag="IV356_001587"
     CDS             4061..5035
                     /locus_tag="IV356_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase family protein"
                     /protein_id="HAP9015276.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGERKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
     gene            5360..7255
                     /gene="asnB"
                     /locus_tag="IV356_001588"
     CDS             5360..7255
                     /gene="asnB"
                     /locus_tag="IV356_001588"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HAP9015277.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(7450..7896)
                     /locus_tag="IV356_001589"
     CDS             complement(7450..7896)
                     /locus_tag="IV356_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAP9015278.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            8124..8273
                     /gene="rpmG"
                     /locus_tag="IV356_001590"
     CDS             8124..8273
                     /gene="rpmG"
                     /locus_tag="IV356_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAP9015279.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            8361..8879
                     /locus_tag="IV356_001591"
     CDS             8361..8879
                     /locus_tag="IV356_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP9015280.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(8956..9912)
                     /locus_tag="IV356_001592"
     CDS             complement(8956..9912)
                     /locus_tag="IV356_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP9015281.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            10078..10884
                     /locus_tag="IV356_001593"
     CDS             10078..10884
                     /locus_tag="IV356_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9015282.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            10881..11870
                     /locus_tag="IV356_001594"
     CDS             10881..11870
                     /locus_tag="IV356_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAP9015283.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            11867..12871
                     /locus_tag="IV356_001595"
     CDS             11867..12871
                     /locus_tag="IV356_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAP9015284.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILLSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            13003..13545
                     /locus_tag="IV356_001596"
     CDS             13003..13545
                     /locus_tag="IV356_001596"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HAP9015285.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            13565..14263
                     /locus_tag="IV356_001597"
     CDS             13565..14263
                     /locus_tag="IV356_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HAP9015286.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            14284..14496
                     /locus_tag="IV356_001598"
     CDS             14284..14496
                     /locus_tag="IV356_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HAP9015287.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            14496..15458
                     /locus_tag="IV356_001599"
     CDS             14496..15458
                     /locus_tag="IV356_001599"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HAP9015288.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            15476..15871
                     /locus_tag="IV356_001600"
     CDS             15476..15871
                     /locus_tag="IV356_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAP9015289.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            16034..16399
                     /locus_tag="IV356_001601"
     CDS             16034..16399
                     /locus_tag="IV356_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HAP9015290.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            16396..18207
                     /locus_tag="IV356_001602"
     CDS             16396..18207
                     /locus_tag="IV356_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HAP9015291.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(18269..18436)
                     /locus_tag="IV356_001603"
     CDS             complement(18269..18436)
                     /locus_tag="IV356_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HAP9015292.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            18684..19673
                     /gene="galE"
                     /locus_tag="IV356_001604"
     CDS             18684..19673
                     /gene="galE"
                     /locus_tag="IV356_001604"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HAP9015293.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            19685..21169
                     /gene="galT"
                     /locus_tag="IV356_001605"
     CDS             19685..21169
                     /gene="galT"
                     /locus_tag="IV356_001605"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HAP9015294.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            21193..22173
                     /locus_tag="IV356_001606"
     CDS             21193..22173
                     /locus_tag="IV356_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP9015295.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            22262..23086
                     /gene="tsaB"
                     /locus_tag="IV356_001607"
     CDS             22262..23086
                     /gene="tsaB"
                     /locus_tag="IV356_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HAP9015296.1"
                     /translation="MYYCTSFAFGIFILRIKKYATMEGENVIAERIKYMITLGIDTAN
                     QTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAIDQLFADLQISPKDIDRIAVSDGPGS
                     YTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAANCIGVDNIIVPMFDARRKNVYAGAY
                     RWKENRLETVLEDVHISASDLFTQLQKLNEAIYFVGSDCHKFFSEIKEILPSAMINTV
                     PAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKRVEAEEKWLETHTPGDESYVEKI"
     gene            23070..23612
                     /gene="rimI"
                     /locus_tag="IV356_001608"
     CDS             23070..23612
                     /gene="rimI"
                     /locus_tag="IV356_001608"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAP9015297.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            23619..24083
                     /gene="rimI"
                     /locus_tag="IV356_001609"
     CDS             23619..24083
                     /gene="rimI"
                     /locus_tag="IV356_001609"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAP9015298.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            24080..25096
                     /gene="tsaD"
                     /locus_tag="IV356_001610"
     CDS             24080..25096
                     /gene="tsaD"
                     /locus_tag="IV356_001610"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HAP9015299.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
BASE COUNT         8327 a         4400 c         5377 g         7567 t
ORIGIN      
        1 aaaaaaagcg ttagcaacta tgcttaaaaa gcatatcgac tgaataaact aagcattgga
       61 caggctgaaa gactacattt aaaatgaaat gcgaagaaac aatagaaaat aaagttgcct
      121 tagaaccata gttgaatcac ctaacagtcg tgaagggaga ataagagaaa tggcagaaaa
      181 acaaaccgca ggacgagatc aattaggaga ttttgcacca aaatttgcag aattgaatga
      241 tgatgtttta tttggacaag tatggtccag agaagaatta tctgctcatc agcgtagtat
      301 catcaccata tctgcattaa tttcaggagg aaattttgaa caattgccag ctcatctgaa
      361 gattggcaag caaaatggca ttactagtga agaaatagca gaaatcatta cccatttagc
      421 tttttatgta ggatggccaa aagcttggtc agcttttagt ttagcaaaag aaatctattt
      481 agaagaaaat agcgaagata agaaagaggc gtaaatgacg acaaaacacg aagaaataca
      541 caatggcgtg atttttccag caggtgaaaa aaacgaagct tacgctcaag tatttaccgg
      601 gcaaagctat ctgaatatgt tagtgaatga tcccgaagtt tctgttggtg taggtaatgt
      661 aacttttgaa ccaggttgtc gcaatcactg gcatgtccat aaagacggct atcaaatctt
      721 acttgtgacc ggaggagaag gctggtatca ggaagaagga aagccagcaa gacgattaat
      781 ggctggagat gtcgtcgtaa cgcacaaagg gattaaacat tggcatggtg cgacaaaaga
      841 cagttggttt gaacatttgg cgatcactgc tggtaattca gagtttttag aacctgtaac
      901 agatgaagtg tatgaaggat tggaaaatca ataatgtcaa gcttgaacag ctcctgaaag
      961 tagattttaa tcgaactttc aggagctgct tttttgattc agtcttttat aaatagaaaa
     1021 tagggttaat aataggaatg agaagcacgt cgaaagatct taatattgat aatcggctgg
     1081 gcatacatga tttccacgtc atcaatcaaa ctacctaaca gatgataatc ttcccgatca
     1141 tgtcggggat tacctaatag ttcttgataa tagatttcca tactagggtc ccgaggattg
     1201 ttcagcaaat cagcaagtac atctaaatct tctggctgag tttctgccgt accctgtatc
     1261 tctatgaaaa gcccttcctc agcaaattct actccaatac gtatttcagt tatttcatgg
     1321 gaatataaat aagtaagaag ctcatcgatg attctttttg ataattcttt ttccaagtgt
     1381 ctttttttcc tttctgacag cggtaaagtt atctagtatc ggtacaagga tacctgcaac
     1441 gaaaccagtt gaaaaaccac tgttatatag atttagtcct ccgtgcaaag tgctgacgtt
     1501 atggacaaga gcaatatgta gtacaccagc tattacaccg taaaaactgc cgtaaaaacc
     1561 gcttatgggc gcgagacctg tcccaaacac agctgcaaca agcatgccag tactggtgat
     1621 ctcatgaaaa gttccaaaca aagaagcaat aaatattccg actagtatcg gaaaactgtt
     1681 ttttaaatga caaccaaaag cactgaaacc caccgcagat aaaatagcac cgatgacagg
     1741 tccatttaac tgaccgccaa ccagcaaaac ataagaagac agcatcagac caactaagcc
     1801 tatgttgatc aaagtagcac caataccaga attagcaatg aaatcagttg tcaattttcc
     1861 agatgaatcg aaaatttctc gaatccccaa aagccgaaag gaattataat agaaaccaat
     1921 tccgactgtc agcgaaaaaa agccaaaaat aatccaaatg agaggaaagt gatattcatt
     1981 gaaaaccaat gtattttcga cgattgaata gctgaataac ctcaaaacag cagtaaaagt
     2041 catcgcaatc aacccagagg tgaatccaat attataaagt gtgaatccac gatggaaaac
     2101 taaagtttga gcagctaagg gcggaagaag tagaccaatt gctatgccag ctaaattccc
     2161 caataaaata cctatcagta aaggaaaacg cataccaaaa gtgatataac taacgaccgg
     2221 tgataatgcg ctaccaaaca gtccgatcat gatgtactga gaaaaaggtt tattgacaaa
     2281 tacagcgtat agatacacac ctaaaatgat tgagatagaa ttataaaggt ttttgccaaa
     2341 aaaagagaaa ccggtaactg ttagaatcga agcaaataag ggaccgttta aaatcacctt
     2401 gtgccgataa gctaaaagca cagaaagtaa ggtcaaaatc cctacattta tgaatgcgct
     2461 tccgaaaccg cctaaagcaa aataatctgt caaaagattg cttggcgagg taagaatagt
     2521 tagcaatcca ctccaattat cagtaggagt attagaaagc aagccaataa aaagaaaaaa
     2581 aacacctgta aaaccaagat aaaaatactt tcttttctgt gaaacgattc gtttttgagg
     2641 atgaatataa ataacgtcag tttcgttttc cattacacac cttctttttc attttcttta
     2701 actataactt gaaatgaaag atttggacaa ctatcattta ggtcaaaact aaaaatgtaa
     2761 gggaacccat tgaatttaac caaatttttt taattttgca aaaaaaagtt aaagaagact
     2821 gaaaaaaaat ttaaaatata acgttttgag taaaatgttt gcaaaaaatg ctaaaaatag
     2881 ggtacaataa aacaacatat actgcagtaa agaagtgggg gagttttaat gagaagaaaa
     2941 gtctatacca aggatcaaat tctaaaagct gcttatgatg ttgttgcaaa ggaagggttt
     3001 aaaggattta ctgcgagaaa tattgctaaa aagatgggga tttcgacaca gccgatttat
     3061 ctggaattca aaaacatgga agatttaaaa aatacgttgc tggattctat ctttgaacaa
     3121 ctaaaagaag atgttttccc tattgaacgt actggtgata aaatcattga tctcggtttg
     3181 aactatatct actttgcaaa aaagcatcat agtctttaca tggcattgta cattgatgaa
     3241 catggggacg gaaagaaaat gcatgatttt tcatacaatt atttccgtga aatagttaaa
     3301 gaagatgaaa gatacaatca attatcggat gaatatgtcg atgctctgca tactggtaca
     3361 tgggtagcag tgactggctt agcgtcattg atgtcatcaa acatcatgca tccaacagaa
     3421 gaacaaatca ttgcactgat caaacggaca attgactcga ttttagcatt agataatcct
     3481 gaaataatca gatagtgttc tatcagtatg aatttgatcg gtaagtccgt tggctgcaaa
     3541 ctgtcaatgg acttttttgc taaaaaaagc gatttctgtt atttatctat tagaaatagg
     3601 cttgacattt cgtgaaaaaa gtttaaaaat agtacttacg gaaggttggc agagtggtaa
     3661 tgcaccggac tcgaaatccg gcgaaccggc taataccggc gcgcaggttc aaatcctgta
     3721 ccttccttat atcaacgatt agaggttgtg aagaagctgt cctgcatcaa gtaataagaa
     3781 cggccaaaca aaaatagctt ttcctatttt ttcgtttgat tgggcttatt accgcagatg
     3841 caagcttttg aacaccgttt gttcggaata aggggctgtg acaagacttt tgtcacagcc
     3901 ccttattgtt gtacttttaa cctacaatat tttttgattc cccctgagta ctatttttta
     3961 taaatgctag taaatcaatc ttctttggcc tttttttgat aaaaaaaata ctagatgtaa
     4021 gataaaagtg taaaaacgat ttgttttagg acgggaaacg atgtgtaccg caatcactta
     4081 tgcaacgaaa gaccattatt ttggaaggaa ttttgattat gagatgtctt ataatgaagt
     4141 ggtcactatt actccaagaa attatcgttt cgattttaga aaggtaaaaa atttagataa
     4201 acattatgca atgataggaa tagcagctgg ggtatccaac tatccactct attatgaggc
     4261 tacaaatgaa aaagggttga gtatggcagg actgaatttt cctggcaatg ctgattataa
     4321 agaattacaa gaaggaaaag ataacgttgc accatttgag tttattccat ggatactagg
     4381 gcaatgctca accatagacg aagctaaaga attattggct actatcaatc tagtcaatat
     4441 cgattttagt gaaaaactac ccttgtcacc tttacactgg ttattagctg ataaagaaaa
     4501 atcgatagta attgaaagta tgaaagatgg acttcattta tatgataatc ctgtcggtgt
     4561 gttgacaaat aatccgccat ttgattatca attatttaat ctgaacaatt atcgctcgct
     4621 atcaaatgga acaccagaaa atcatttttc aaaccagatc agcttgaatg tttatagtcg
     4681 tgggatggga ggattgggct tacctggaga tctctcttct gtttctcgat ttgtaaaagc
     4741 cacatttact aaaatgaatg ctgcatcagg tgattcagaa tctgaaagta tcagtcaatt
     4801 ttttcatata ctaggctcag tcgagcaaca aaaaggagta tgcgatactg gagaaagaaa
     4861 atacgaatat acgatttatt cttcttgctg taacgttgat aaagggattt attattatcg
     4921 tacgtatgaa gacagtcaaa ttactgctgt aaatatgaat aaagaagact tggatcgtca
     4981 tgaattggtc agttatccag tcataaaaga gcaacagata aactatgtca attaattaat
     5041 gaatagatcc gtttggtatc atattttctg atacagtcat aattagacac gatctttagg
     5101 tcgtgtcttt ttttgctggt ttttttggaa atagcatcca ctaatatttt tttaacacga
     5161 agagaataag gtagcctcaa aaaagaaaac atggtaaatt agatattggg actttatttt
     5221 ctgtaaaaac agaaactttc atcttttgtt ttcacgtgac gaaattgtaa gagagaaaat
     5281 attcgtccgc tatttattct atgataagat gcatatgaat gaaataaaca gtaattttat
     5341 attaggatgt gaaagttaaa tgtgcggtat tgtaggtttt gttaacgaca aggacaacaa
     5401 aaaaacaatt attaatacaa tgatggatcg aatcgttcac cgtggaccta atagttcagg
     5461 agaatatatc gataaacatg ttgctttagg attcagaaga ttaagtatta ttgacttaga
     5521 gggcggtact cagcctattt acaatgaaga tcggacaaag atcattattt ttaatggcga
     5581 aatctataat taccagcctt tgagagaaga attgattgca gctggccacg tttttcaaac
     5641 acatgcagat acagaagtcc ttttgcatgg ttacgaagaa tggggaacag aattattgca
     5701 aaagatccgc ggaatgtttg cttttgctat ttgggataat gaaaagaatg agttattcgg
     5761 tgcaagagac cactttggga tcaaaccata ttattatgca gaaatgaacg gaacatttat
     5821 gtttggttca gaaatcaaaa gttttctgcc tcatcctgat tttaacaaag aattgaacaa
     5881 agaagcgttg aaaccttata tgactttcca atattctcca ttaaacggcg aaacattctt
     5941 caaagatgtc tatcgtttgc ctgaaggcca ttattatacg tataaagatg gaaaaataga
     6001 cattcagcaa tattgggatg cagattttga aacaaaagaa acgcattccc gacaagaatg
     6061 gatcgaaaaa atcgacgaaa ccgttcaagc ttctattgaa gcacatacgg tcagtgatgt
     6121 agaagttggt tctttcttat ccagcggggt tgattccagt tatgtaacct ctgtattgaa
     6181 accagatcat tctttctcaa tcgggtttga tgataaaacc tataatgaag cgattgaagc
     6241 cagaaaacta accgaactat tggacttaga taatacagca gcagtgatcg acggagacat
     6301 gtcgttcaaa gcattccctt tgatccagta tcacttagat gaacctgatt caaatccttc
     6361 ttgcgtacct ttgtactttt tagcaaatct tgcttcacaa agtgtgcggg tagtccaatc
     6421 tggagaaggg gcggatgaac tgtttgcggg ataccaaacg tatggattcc atacgaattc
     6481 aaaattcatc cgtgtgattg ctcaaggatt gaaaaaatta ccaaaaggaa cacgctataa
     6541 tttaggacgt aaaatcggaa aaatgaaaaa tttccatgga cggatccatt tatatgaatc
     6601 acttgctcct gcaaaagaat attttatcgg tcatgctcga gtgttcgaag aatcagaagc
     6661 atcagaagtg ttaacaccaa aatatcaaac agcaccatct gtggatgaaa tcatgactgt
     6721 tcattacgag aaaacagaag gaatcaaaga tgaagtcaat aagatgcaat atgtcgatct
     6781 tcatcaatgg atgccaaaag atatcttgtt aaaggcagat aaactttcta tggcaagttc
     6841 tttggaagtc cgagtacctt tattggatat cgaagtcatg aaattggctc aacaaatacc
     6901 aagtaagttt ttattgaatc aaaacaacac aaaagatatt ttcagacaag ctgcgaacaa
     6961 acatcttccg gaagaatggt cgaatcgtgt gaaattagga ttccctgtgc caatcaaagc
     7021 ttggttgaaa gaagaacacg gctacgaaca agtcaaagca ttattcgaag cagattttgc
     7081 aaaagaattt tttgatcaag aaaaaatcat gaagttgcta gatgaccatc acgaaggacg
     7141 taaagaagag caaagaaaaa tctggacaat cttcagtttc ttgacatggt ataaagtcta
     7201 ctttgtagat gaaacgattc cgcaagcaga agcaatcgac tatgtgactg tttgatgaaa
     7261 atcaaatatc aataaaaaag aggttttctc ctaccgttta acactgagtg ataagaaaca
     7321 atttcaaaaa acagctcttc ccgttttata gatattatga cttatggttc ggagttggca
     7381 gaggaacacc attgtttcga acataagggg gttgtgacac gattttcgtc acaacccctt
     7441 tacatatgtt caataatcga tttctttttc ttttgtccca tcttttttat aaatgaacaa
     7501 agttgattct ttgttttgtg ctacttgctt tcctttttcg attgcttctt tttttgtatc
     7561 aaaatggttg cttgcctttt ttgccccttt agatttcacg atccattgtt cttcctcata
     7621 ttctacgatc acatctgaat caagcagttt tccagcacga ggattcgtat cgtgttcatc
     7681 cgtcttgctt ggattttttt ctttttcgaa agttcgtttt tctgattcac tagcatcttc
     7741 ataccatttt tttgcttgat caatggcaat tgggatcgca cggttatcag ggtacccttc
     7801 atctaataat gcatttgcga tgtcgattgc tttttttctt gtcaatttat ctaagttttt
     7861 cattgatgca ggaaagtcct tcatgttcca tggcatatta gtatccccct ttattaaaaa
     7921 acataatcta tataaacaag tgtaagggta tttatacaaa aagaaaaaga ttttgtttga
     7981 gaagtaaaac cgttgtattt atcgtcaagt agttttactt aacaaaatcg tgaaaaacac
     8041 tagcaatcta gaaaaaatca tggtaagata atcaagtctg agagtcatct tagaggattc
     8101 ttgtaaaaat gggagggaaa aacatgcgcg taaacatcac tttagagtgt acttcttgta
     8161 aagaacgtaa ctatctaaca agcaaaaaca aacgtaacaa tcctgatcgt ttggaaaaac
     8221 aaaaatattg cccacgcgaa cgcaaagtta ctttgcaccg tgaaacaaaa taatgttttt
     8281 aaagttctca attccttgct ggtcaaagaa ttgagacttt ttttatctca aaacatctaa
     8341 aatcataagg agcggataat atgtttattt ccatgtgggc acaagataaa aatggtctga
     8401 tcggcaaaaa tggtttgtta ccatggcgat tgccaaatga tatgcgtttc tttcgcgaac
     8461 acacaatgga tcgaatttta gtgatgggaa gaaagaccta tgaaggaatg ggggatcttt
     8521 cacttcctta tcgccatatc atcgtgttga caacgcaacc aaattttcgc acgaaagaaa
     8581 atgcggaagt aatgcattcg atcgatgaac ttttgtcgta tagtcaaacg atctcagaag
     8641 atatctatgt ttcgggtggt agtcggattt ttcaagaact tcttccttac actggtcgga
     8701 tctggcgaac attgatcgat agcacgtttg aaggcgatac gtatattggg aatattgatt
     8761 tttcagactt cgcccttata gaggagtatg aggggataac ggatcaagaa aatctatatg
     8821 cccatcgttt tcaaaaatgg gaaagagtaa aaaatagggt tgcttcaaaa gaagaataaa
     8881 atctatgcgt ctagtttgtt aataagaaaa aaagcatctc acgactaatc gtgaagatgc
     8941 tttttttagt taaaatcaat ttagtttttc tttgatatca ttgaccattt cctgactggc
     9001 aataggtccg ttatatagcc aactagattc aggtccgaat tgcagtacat gattgtctgt
     9061 cactgctttt agattcttcc agcttggttc attgaacatg gcagcatctt tgtcactgtt
     9121 cacaaggatg atgtagtcag catctaattc agctagcttt tcagaggaaa cagcagacca
     9181 gtcagaagtg gcttttttgg agacctcttc cactagatca ggaacaccaa attccagatc
     9241 gtcgtatacg attcttccac ttgaccgatt tttgctgacc ataaaggctg agttgttggt
     9301 cacccacaac actgcagctg tcttgttctc gattttatct gctagttctt ctcgagtttt
     9361 cttgatggat ttttgataat cggaaatgat tttttctgcc tctttttctt ttgccaaagc
     9421 tttgccgaca tcttttagtt gttcttccca tgtgacatct gttccgtttt ttacaacata
     9481 agttggcgcg attttgctat attgttcgta tttcccgcct tcgacagtag cggaagaaga
     9541 aatcaacagc aaatcaggct caaagcttaa cactttctca taaggaaggt cataagaaat
     9601 cgttgggaca tcctttaaat catcttgcag ataatcttga atggaaccac tgccaacagt
     9661 ccactgggcg ataggttttt cccctagtgc aatcagatag tcttctaagt aactgccgat
     9721 gatccgtttg ggcgcgtttg gaatctctac tttatgtcca agtgtatctg tgactgtatg
     9781 agtactattg gatgaagtcg tcgaattggc agttgtagct gtttctttat ctgaagaggg
     9841 ggagcaagcg ctcagtactc cagccagcag caatatgcta gataatgtga atacttttgt
     9901 ttttaatttc atttctttcc tcctaacata attgagaatc tttctcattg gttattattc
     9961 ctgatatttc gaacgctgtc aaccgcttca tttggctata gatatgaaag tagcgcttga
    10021 cgaaatgttg aaacagcgtc ataattgaga atgattttca gcgaaaggat gggtgaaatg
    10081 acgagattaa gagcagctga cattgcagcc ggctacgaaa acaaaaaaat cattgaaaac
    10141 atgtctgtta cgattcctga agggaaaatc actagtttga ttgggccaaa tggaagtgga
    10201 aaatctactt tattgaaaag ttttacccgt atactacctg tgaaatcagg aaagatcatt
    10261 gtcaataact ctgatatctc tacatacagt tcaaaagaac ttgcaaaaaa aattgcatta
    10321 ttagcacaaa ctagtgaaca ccctacaggt atgacagtag aagaagtagt atcttacgga
    10381 cgataccctt atcaaaaact gttcagtggc atggacacgc aagatcatga agcaattgag
    10441 tgggcgttgg atgctacagg tctagctgga tttcgtatgc gggatatcgc aacgctgtct
    10501 ggtggacaaa cccagcgtgt ctggatcgct atggcgcttg ctcaggaaac agatatcttg
    10561 atcttggatg aaccgacaac atttttagat ccggcacacc aattagagat cctacagtta
    10621 ttgactgaaa tcaatcaaat gaaacaaaca acgatcttga tgtcgattca tgacattaat
    10681 catgcttcac gtttttcaga ttatttatta gcaatgaaaa acggtaagtt gatcacagaa
    10741 ggtacacctg aagaagtgat cacaaaagag tgtatgaaaa aaatatttga gattgatgca
    10801 acgattgtca cgcttccaag aacaaataaa ccagtttttc taacctatga tttgttgcca
    10861 aaagagcagg aggatcaatt atgaggacta tgaagaaaaa tagactcctg cttttggtct
    10921 gttttgttct tttgattatt ttttttgttg ctctttcaaa tggcgcagcg actgtgggaa
    10981 aagcagattt ttggcaggcg ttgtttgatt ttgatagatc aaaacaaagt caccaaatca
    11041 tacgaaatat tcgtttgcct cgtgtggcgg gagcatttct tgtagggagt tgttttgcat
    11101 tgagcggtgc attgatgcaa ggagtgacaa gaaatccttt agcagattca ggcttactag
    11161 gaatcaacgc gggtgcttcg ttggcaatgg cccttagttt tgctttttgg cctaaagctt
    11221 ctgatttttc tgtgtttcta atgtcattgg caggttcttt tgctgtaact ttgctcgtat
    11281 ttggtttttt gcagttttcg aaaatgggca tgaatccttt acagctgatt ttagctggcg
    11341 tagctattag ttcttttttt actgctatca gccaagcact tacccaattc tttaatctgc
    11401 agcaggatct tgctttttgg tttgtaggcg gagctgccaa tatcacatgg aaacaattag
    11461 cagtattgtt tcctttatat atacttgctg ttttggtttc tttttcatta ggaaaagcaa
    11521 tatctttgat tcatttgagt gaaacacatg cattagctct tggaagtcat cctaaacgaa
    11581 cgcggttgat tgttttctgt ctagttgcag tgttagcagc cattgccgtt tcgttagtcg
    11641 gacctgtttc atttattggg ctgttggttc cgccagttgt tcgcggaatg gttggaacgg
    11701 actatcgtta tgttctacct gtctcttttt tagttggcgg tggattggtt atgttggcgg
    11761 attttacagc gaggatgatc aatccccctt ttgaaacacc ttttggatta gtcattgcat
    11821 tgattggcgt tccgttttta ctgatacaag taaggaggga acaacggtga aaaaaatata
    11881 ttggacgttc tatttcttgc tttttgtact tgtcatcctg tctataggta gtttaatgat
    11941 tggtacgcct tttatttacc tggatcagct ttttgccacg ttcataggga aagaatcatc
    12001 ttctttggcg ctgattgtta gagaatttcg agttcctcga ttactgatca gtttattagc
    12061 aggagcttgt cttggcgttt ctggttatat cttgcaagga gtaacaagaa atgaattggc
    12121 agattctagt atattgggca ttaatgccgg agcaggattt ttagtgatgc tttatttagg
    12181 tttcttttcg cactattcgc tgccgtttct attgctagtt gtagcctttc taggtggtgt
    12241 tttagctgct tgctgtgtct atcttgcggc ctatgatcga aatggctttt tgggtatgaa
    12301 tcgaatctta ttgtccggta ttgccgttaa tgccggcctt tctgcattaa cattgctatg
    12361 cacgatccaa ttatctaagg aaaattatgg atttgtgaat gcatggttag cgggatcaat
    12421 ctggggtgcg agctggcctt atgtttgggc attgcttcca tgggcggtta tcttaattcc
    12481 gctaggagga ctttatgcac agaggattgt attgctatca tttggtcaag aacgcgcgca
    12541 aggattaggc cttaacgtgg ctaaaagtca aaaaatcctt ttgttgttag ctgttgcttt
    12601 ggcaagcggt agtgtagcgg tgacaggtag tttatctttt gtaggactac tagctcctca
    12661 tgctgcgaag ctagtcgtac gtaaagaaaa taactggacc tttgttctga gcggtttgtt
    12721 cggttccatt tttctgctta gtgcagatat ggttgctaga gtgattctac taagtgggga
    12781 agtacctaca ggaattttga ttgccctttt tggtgcgcca tattttctgt atgcactttt
    12841 tatcagacaa aaacacgcgc tgaacagttg aaattcatta aaaaaggaag gccaatcatt
    12901 tctaggtctt ctttttattc tatttatgca tttatttgaa agttcgattg ctatttttct
    12961 ttttttccta taccatttta tgagagaagg aagggtgagt ttttggacca attgaaagta
    13021 agattacgcc ggaaaggaat cgaaaagctg aaaaatctgg ccaaaagtgg caagaaaaag
    13081 gaaaaagaac agcgaatcta taaacagcta ttcgccagcg agtactggaa gtcagcaaaa
    13141 gtgataggga cgactttatc gaatgaattt gaactggata cacagccggt tatccaacga
    13201 gcagaaaaag aacaaaagaa aatagttgta cctaaaactt tgccgaaacg tcagatggcg
    13261 ttttatgaaa tggatgaaca gtccgttctt gtacgttcga gttttggtgt tcttgagcca
    13321 caatcagaga agctctattt gccggagatg atcgatctcc tcattgtacc aggtattatc
    13381 tacaatagag ccggttatcg aatcggtttt ggcggtggtt attacgaccg gtatttaaat
    13441 aattttcata aaaaaacatg tagccttgtt tttcgtgaac aattgaatga acaatggcaa
    13501 ccggagagct ttgatcagaa gatccaacaa ttgtttattg actaaaatga aatgggaggt
    13561 tttcatgaat tatcaacagc aaataaaatt gcgtgcatgg ttaagacgac cgttatggac
    13621 ctatgctttt ttagggatac agacagcggt cttcctcatg atggaattat ttccgcgact
    13681 tgagatccct tattatgccg gaatgtatgg tccttatctt gttcacttca atgaatggtg
    13741 gcgtttagtg acaccaatct tcatccattt tggactgatg catttcgtaa tgaactcact
    13801 gatactgtat tttatggggc agcaaatcga ggcaatctat ggccattggc gttttttctt
    13861 gatttatatg ttcagcggga taatgggaaa tacagcaagc tttgctttta acgaagcgaa
    13921 tgttctgtct ggtggtgcaa gtacttcgat attcggtttg ttcggtgcgt tgtttatctt
    13981 agggtttcat tttaaacata acccagcgat ccagcagcta gtcagacatt ttcttttatt
    14041 tattgtgttg acatttgttt ttggtcttct ggatacctct gtagatgttt ggggacatgt
    14101 cggtgggcta attggcggat tagtgttagg gaatgttttg ggtctaccga aacaacagac
    14161 aagctattcg atacaccaaa ggattctttc tacactagtt tttgtatttc tttttgtaat
    14221 atgtatttta ctgggtttaa aaaaatatgg tttacttgta taatatgaag gaagtgctta
    14281 aagatggaga gcttatatga tgtacagcag ctgttcaaaa aatttggcat ctttatctat
    14341 gtgggtgcac gcatctatga cattgaatta atgactatcg aattgcgtaa tctgtatgat
    14401 agccgtttga ttgatcatga tacatacatg acagcgtggc gcatattaaa aagagagcac
    14461 cgaattgaag aaagccgaaa gaaaggaaat ttgtaatgga caagaagatt attgggattg
    14521 atttaggtgg aacaacagca aaatttgcaa ttttaacacc agaaggagag attcagcaaa
    14581 aatggagcat cgataccaat attttggatg atggtaagca tatcgttcct gaaatcattg
    14641 aatcaatcaa tcatcgtttg aatttatata atatgaaagc cgaagacttt atcggaatcg
    14701 gcatgggtac cccaggaagc gtggacagcg aagctggaac ggttattggt gcgtataact
    14761 taaactggac agaagttcaa tttgtgaaaa aactgatcga ggcaggaaca ggaatcaaat
    14821 tcgctatcga taatgacgcg aatgttgctg ctttaggtga acgatggaaa ggtgctggag
    14881 aaaacgatcc agacgttgta ttcgttactc taggaacagg tgttggcgga ggtatcgttg
    14941 ctggcggaaa tttgattcac ggcgtgagcg gagctggagg agaaatcgga catatcactg
    15001 tggatcctga agggttcgaa tgtacttgcg gtaaacgcgg atgtttagaa actgtatcta
    15061 gcgctacagg tgtggtacgc ctaggtcgtt tcttggcaga agaatacgca ggggattcaa
    15121 aactgaaagc aatgctagac aacggagaag aagtaacaag taaagatatc tttgaaatgg
    15181 ctcaagaaga cgatccgttt gcattgatgg ttgttgatcg cgtatgcttc tacttaggtt
    15241 tagcttgcgg aaacttgggg aatacattaa atccgtcaag tatcgtgtta ggtggaggag
    15301 tatcggcagc aggagaattt ttacgtagcc gtgtagagaa atattttaaa gaatttactt
    15361 tcccgcaagt aagagaatca acaaaaatca aattagcaga gcttggtaat gaagctggtg
    15421 tcattggtgc tgcctcatta gccttgaaat ttgcttaaaa aaacggaggc attacatggt
    15481 tttatgggta attaatatca ttttgctatt gattgtgctt gcaatcatcc tttgggaagt
    15541 ctatctacga gtaatggcca aacgttcagc aacgactttg acagaagaag aatttcgaga
    15601 aggaatgaga aaagcacaag taatcgatgt tcgcgaaaaa gatgtgtttg atgctgggca
    15661 tattttaggt gcaagaaaca tcccttacac tgttttgaaa gattcattag gatctattcg
    15721 aaaagaccag cctgtctata tttacgatca aaagaaaagt ttgagcatcc gtacagcaaa
    15781 taaattacgt aaagcaggtt atcaagagat ttatttactt aagggtggat atgacggatg
    15841 gtctggaaaa atcaaaagta aaaaagtata aaacagatga ttgtatgaca gctttaaaaa
    15901 ccgaatcaat cattagattt tgaccaagat cacatgaacg gcgcaatgga tagttgtgcc
    15961 gttcattttt tttattttgt gctattatct acatatataa gctaagcgaa aaggtagaaa
    16021 gaaggaaaca actatgatca aattaaaacg tgtttacctt gatgctgaaa aagaggatgg
    16081 ctatagaata ctcgtggata gattctggcc acgaggaatt tcaaaagaaa aagcgcagtt
    16141 agatctgtgg ttgaaagaaa ttgcacctag taatgaagca cgcaaaactt ttgaccatgt
    16201 accagaacga tttgcttcat ttgcaaagaa ataccagcaa gaattgattt tcgaagaaga
    16261 aaagaagcaa gctattttta aactcagtca acttatgaaa gaacatccag tcattacttt
    16321 tgtttatggt gcaaaaaatg aacatcagaa ccatgctgtt ttattgaaaa aatttatcga
    16381 aatggaggca tgcaaatgaa aatagggatc attggtgccg gacctagagg attaagtgta
    16441 gcagaaagga ttctccataa taatcaggac agacattctc ttgaactttt tcttttcgat
    16501 cccaatggtc ctggaggtcg agtttggcgg ttgaatcagc caccggagtt attaatgaat
    16561 tctgtttctc aacaagtgac gctttttaca gatgaaacat tgtccagtgg aggattggta
    16621 acacagggac ccaacttgtt tcaatggagt aaaggacctg ctacagatta tatcgaacag
    16681 acggtaacca aaaataagca actaattata gaagaaatca atcgtctgga aaaagatcag
    16741 caatctactc gatgtttata cggactctat caacgctggt ttttctcaaa gttgcaagaa
    16801 gaatttccag cttctattca gtttgtttat tctttagtaa aaaaagtaag caaaagaaaa
    16861 gatggttatc ttttacagac agatcagcaa agctattcta tcgatcagct tgttttagca
    16921 agcggtcact gggaaaatga tgagacagaa gaagaaagag tgtgggtaga ctacgcaaag
    16981 aaaaatgttt tactgtatca gcttccttct aatcctgcag atgtagatct ttcgaagata
    17041 ccgcctaaag aaaatgtctt tttaagaggt ctaggcttaa gtttttttga ttatgtcgga
    17101 ttgtttacag tatcaagagg agggcgcttc gagaacgaaa agggaaaact ggtctatcat
    17161 ccatcaggca aggaaccgat tgtatacagt ggatcaagaa gggggctccc ttattaccct
    17221 cgaggaagaa atcaaaagca aggcggagca atggcatggc cacggttact aacaaaagaa
    17281 aacctggagc aatggcatca gtcgggattt ttgactggcg aaacattttt tgactatctg
    17341 aaaaaagacg ttgagttgtt ttattacaag aaaatcatcg aagaatatca cttgccgatt
    17401 ccaaagaaaa attttgagca tgattttctc tccctctctt cagaggagtg tctcggaaag
    17461 catccagcac taatccctta tagatgggat tggtcgtatt tagaaactcc tcttgcctat
    17521 cagaatgagc ccttttcaga agctagccga atatttattg aagggcagat aaaagaagcg
    17581 gaaaaaggca attgcacagg agcatttgct tcaacatttg atgcattaaa agactggcgt
    17641 gatccaatcc ggcaggctat tgaatggcac gttttttctg ctaaggaata caaagaaata
    17701 ctatggggat ggtttactca tctaaatagc tttttaacga tcggtccgcc aatcattcgg
    17761 acgaaagaat tagcagcact gatagatgcg ggtatttttc atttgatcga accgccattt
    17821 gatattcagc aaaagcacaa ccgctatgtt atttctctac aagataaaga aatcagcagt
    17881 cgctatttga ttgaagctcg attgccacaa acaagctttt ctcgttcaag taatcctgtc
    17941 ataaaaaatt tgaaggaaaa caaacttgtt cgcccttttt cattttcaga taatacagga
    18001 agttatcatt cagaagctat agatgttgag cgaggtacga atcgcgtgat tgatgcttca
    18061 ggggaaatcc agtctgactt ttattgctat ggaatacctg ttgaaggtgt ggattggcta
    18121 actgcagcag tagctagacc ttatacagat ccatggaatc tgagacaggc agataaaata
    18181 gcacaactta tattgactga caaataaaaa tacgcatgat gacttatctg ttttttagaa
    18241 agtcttcatg cgtattttta aataattatt aacgagaaac gcgtttacgc attgcttttt
    18301 tacggttttc ttcgatcatt gcttcttttt cgtcaattgg atcgatcact gtttttttca
    18361 cagaagcaac caaaccagca acggcagcgg ctgttgccag acttcctact aatattccag
    18421 atacaaattt tttcattgaa tccacctcat ttattatttg ttatatctat tatggaacaa
    18481 aagagaaaaa aaggctagtt ttacgtttgt ttgtaaacct ttgcaaaaaa tccttgaaaa
    18541 tgtttactaa atgttttatt ataaatttac catatgaatt tacgaaattt tactttgttt
    18601 gttttcacca taaaagtaaa cttcgttttt taaattatat agaatcaaca aacacaattt
    18661 tactaatcaa aggagtgttt tttatgacaa ttttagtact aggcggagcc ggttatatcg
    18721 gttcgcacgc tgtagaccag ctagttcaaa aggggtatca agtagctgtg gtagataatt
    18781 tgctcacagg tcacaaacaa gcagtacatc cagatgctca tttttatgaa ggagacatcc
    18841 gggataaaga atttctacgt tccgtatttg aaaaggaacc gattgaagga gtaatccatt
    18901 ttgctgcaag ctctttagta ggagaatctg tcgaaaaacc attgatgtat ttcaacaaca
    18961 acgtatacgg tatgcaaatc ttacttgaag tcatgcacga gttcaacgtg aataaaatcg
    19021 tattctcttc tactgcagca acttatggag agccgaaaga gtctccaatc acagaagata
    19081 caccagctaa tcctaaaaat ccgtatggtg aaagtaaatt gatgatggaa aaaatgatga
    19141 agtggtgtga ccaagcatat ggcatgcgct atgtcgcttt gcgctacttc aatgtagccg
    19201 gagcaaaagc agatgcatct atcggagaag atcatacacc agaaacgcat cttgtcccaa
    19261 tcattttaca agtagctctt ggtcaaagaa aagccttggc tgtttatgga gacgattatg
    19321 atacaccaga tggaacatgt atcagagatt atgttcaagt agaagatttg attgctgcac
    19381 atattttagc tttggaatac ttgaaagaag gaaatgaaag caacttcttc aatttaggca
    19441 gcagcaaagg atactcagtc aaggaaatgc tagaagcagc tagagaagtg acaggaaaag
    19501 aaattccagc agaaatagca ccaagaagag ctggagatcc tagccgatta gtcgcttcaa
    19561 gtgaaaaagc gagagagatt ctgggctgga aacctgaata cacagatatc aaagcgatta
    19621 tcaaaacagc atgggattgg catgtcagcc atccaaatgg ttatgaagaa taggggaatg
    19681 agatatgtca atcagtcaaa cgatttgtga ttttgccaca cttgcgatcg aagctggcgg
    19741 atggatggaa atggaccgct tatatttaca gaatcgtctt ttagggatgg taggagaaga
    19801 tgctctagaa agcattgaag taagaccagt taaggaagaa tctgtagact tattggatca
    19861 gcttgtcgct aaggcaagag aaaatggtgt tctttcagaa ttgccagcag aacaagagat
    19921 ttttgaagcg caattaatgg attttctcac accgccacct tcagtcgtca atgcattctt
    19981 tgcacagcac tattcgaaaa gcccagagga agcaactgag tatttcttta atttaagtaa
    20041 gaaaaatgac tacatcaaaa caagagccat cgcaaaaaac atcaaatttc cggcagagtc
    20101 ggagtatggt gaactggaaa tcacaatcaa tttatctaag ccagaaaaag atccaaaaca
    20161 aatcgcagca gaacgcgagg cggtaaaagt agactatcct acctgcatgc tttgcatgga
    20221 aaacgaagga tatagaggtc gcttgaacta tccagcccgc accaatcacc ggattattcg
    20281 aatgaatcta gacggtgaaa gctggggatt ccaatattcc ccttatgctt attacaatga
    20341 acattcgatc attttatcag aacaacaccg cccgatgaaa atcacaaagg aaacatttgc
    20401 tagactgctt cggattactg aagtcttgcc tcattacttt gttggttcga atgctgactt
    20461 accaattgtt ggaggatcga ttctttctca tgatcattat caggcaggac gtcatgaatt
    20521 tcctatggca aaagcaccga tagaaaaact tatcaaacta gaagattatc cgcaagtcat
    20581 cgcaggagtc gtgaaatggc cgatgtctgt gatccgtttg caatcaacag agaaaaactt
    20641 gcttattgaa gcagctaact cagtattgga aaaatggaaa gcatattcgg atgaaacagt
    20701 atctatcaga gctttttcag cagatggtac accacaccat acgattacgc caattgcacg
    20761 aagaagggac aattactttg agttggacct tgtccttcga gacaacaatg tttcagaaga
    20821 acatcctgat gggatttttc atccacataa agatgtccaa catatcaaaa aggagaacat
    20881 tgggttgatc gaagtaatgg ggcttgctgt tttaccacct cgtttgaaac cagaactagt
    20941 agaagtagag catttcttat taggagaaga aaaccagatg gctgaatatc atcgtccgtg
    21001 ggcagaacaa ttaaaaaaag aacatcctga tttgacgaaa gatacggtca ccgatgtcgt
    21061 acaaaaatct gtaggtcagg tttttgcacg tgtactggaa gacgctggag tattcaagcg
    21121 agatgaaaaa ggacaggcag cgtttgaacg atttactgcg attttataaa cgtaaaaaag
    21181 gaggagagac aaatggcaac aattaaagac attgcgcagt tggcaggagt ttctcctgct
    21241 actgtttcaa gagttctcaa ctatgatcct gatctttccg ttggcttagc cacaaagcaa
    21301 aaaatttttg aagcagcaga acgcttaaat tatacgaaac atcgtaaaaa tgcagcaaat
    21361 actaagcaaa cgcttcgcct gatccagtgg tacgacgata cggaagagct tgaagatctt
    21421 tattatttat ctattcgcct aggaatcgaa aaaaaggcag aagaagcaaa cgttacttta
    21481 ttgaaagaaa cgtgggattc cattagtgat cttccggcag atggaacgat cgcactagga
    21541 aaattcgacg aagctcagtt attagaaatg aaaggatccc aaaatgcctt gcttttggta
    21601 gattctgacg gcacttctca aggaatcgac tctctagttg tcgactttaa gtcaagtgtt
    21661 caaaaagtca ttgaacactt tgtctcccat aaagcgcaac atatcgctat gcttgctgga
    21721 acagaatata cgaagaaaaa ccatcagcgg ctaaaagatc ccagaattat ggcatttcaa
    21781 caagttttgg cagaaaaagg ctacgacgaa ggtccaatta tcgaagcaga tttttctgtc
    21841 gagtcaggat atcaagcagt gaagcagtat ttaaaaacga atccgcatgt tcctgatgcg
    21901 ctttttgcag ctaatgatgc attagcgatt ggcgcactga aagcgattca agaaaaaggt
    21961 ttagtggtac cagaagatat ttctgtgatg ggcttcaatg atgtcagtgt agcgaaatat
    22021 gtaacgccct cgctttctac tgtaaaagtt tataccgaat ggatgggaga gctagcagtg
    22081 gagacgattc ttcaattaag taattccaaa gcaccggttt caagaaagat tattgtggaa
    22141 acagagttga ttattcgaga atcaacgaaa taaaagatgg aaaagctgtg ggaaaatgga
    22201 gtgataccgc agcttttttg tgtttcagga aggggcaaaa tttgcccgcc agcagataat
    22261 catgtattat tgtactagtt ttgcctttgg tattttcatc ctcagaataa aaaagtatgc
    22321 tacaatggaa ggcgagaatg tcatagcaga aaggatcaaa tatatgatta cattaggaat
    22381 agatactgca aaccaaactt tggcgatcgg tgtggtagaa gacgaacaaa ttcttggaca
    22441 aatacaaaca aatatcaaac gcaaccacag tgtaacactg atgcctgcaa tcgaccaatt
    22501 gtttgcagat cttcaaataa gtccaaaaga cattgaccga atcgcggttt ctgatggtcc
    22561 cggttcttat acagggcttc gtataggtgt aacgacagca aaaacgattg cttatacatt
    22621 agataaagag ctagtaggag tatctagtct gaaaaccatc gcggctaatt gcatcggtgt
    22681 ggataatatt attgtgccca tgtttgatgc tcgaagaaaa aatgtatacg ctggggcata
    22741 ccgctggaaa gaaaatagat tagaaactgt acttgaagat gtacatattt ctgcttctga
    22801 tttgttcaca caactacaaa agctgaatga agctatttat ttcgtcggga gtgattgtca
    22861 caaattcttc tctgaaataa aggaaatatt gcctagtgcg atgattaata cagttccagc
    22921 atgggatatt ccaagtggtg taactgtggc tcaattaggt gctttagttg aaccagttgc
    22981 agagaaacaa gcttttcttc ctcgctattt aaaacgagta gaagcagaag aaaaatggtt
    23041 ggagacgcac acacctggag acgaaagtta tgttgaaaaa atttagagcg tatgccagaa
    23101 gcttttttca agataaaatg atttatacag aaaaaacagt cgaacaaatc gatcgtcgtt
    23161 acgtactaag agaattgact acagaagata tcaaagagct gctggatgtc gaacgagaag
    23221 tctataatgg cgaattgcca tggacaaaaa gtgcctttat atcagaattg aagtcaccgc
    23281 ttcctcatct atatctaggt atctttgata atggaagaat gattggtttt atcggttcaa
    23341 gagcgttcgg tttagattgc catatcacga atattgccgt tcgaccggca tatcagcgta
    23401 aacgaatcgg ttcgctgctt attgacgaaa tcgagaactt tgctataatg aatcgctgtg
    23461 agacgatgtc attagaagtg cgtatgagta atcaagatgc acaaagactt tatcggaaat
    23521 tggggtttca agcaacaacg atcaaaaaaa gatattacac tgaaacaaaa gaagatgcgt
    23581 tggatatgat aaaactttta gaaaatgagt gagattagtt gatttgcaga aaaaaagatt
    23641 ttgatgaagc gtacttggca gaatgcgtat ggatgattag cgaaaatgct tatccacatg
    23701 gttcaccttg gacgaaaatg cagtttttgg cagacatcca acagcctcac tctgattatc
    23761 tgcttttagc tgaagataac cagatctgtg gctttattgg atactcgaaa gtaatagatg
    23821 aagtcgagat cacaaatatt gctgttgcag tttcagaaca aggaaaaggg catgcacggc
    23881 atttgttaca attactgatt acggaacaaa taaaagattc gctgcatgtt tttttagaag
    23941 tacgtctatc taatgaagca gcaagaaaac tttatgaatc agaaaagttt cgtatattag
    24001 gtaaacggaa atcatattat cgcaatccga cggaagatgc gatcattatg agcagaaagt
    24061 taaaaacgga gacgatgaaa tgaatgaaga attgattctg gcgattgaat caagttgtga
    24121 tgaaacgagt gtagcggtcg ttagaaatgg aacagagatc ttatctaaca tcgttgcttc
    24181 tcaaataaac agtcataaac gttttggtgg cgtagtacct gaagtagcta gccgccatca
    24241 cgtagaacaa atcaccttat gcttggaaga tgcactggta gaagctggtg tgtcggcaga
    24301 agatttatcg gcagtcgctg tcacttatgg accaggactt gtcggctcgt tgctgattgg
    24361 tatttctgca gctaaggctt ttgcttgggc acaccaattg ccgcttattc ctgtaaacca
    24421 tatggcaggg catatctatg cagcccgtct ggttaaacca ttccagtttc cattgatggc
    24481 acttcttgtt agcggaggac atacagaatt agtctatatg caagaagatg gatcatatga
    24541 aatcattggg gagacaagag atgacgcagc aggagaagct tatgacaaag ttggaagagt
    24601 attaggtctt tcttacccaa gcggaaaaga aatcgatcag ctagctcatc agggaaaaga
    24661 taattaccat tttccgcgag cgatgatcca tgaagataat tatgatttca gttttagcgg
    24721 attaaaaagt gcatttatca atttggtgca taatgcacaa cagcgtggag aagatctaga
    24781 caaaaatgat ttagcagcta gctttcaagc aagtgtgatc gatgtattga ttactaaaac
    24841 acttcgagct tgtcaaaatt atccagtcaa gcaactgatt atagctggag gtgtagcggc
    24901 caatcaaggg ttgcgtgaag gattgcagga tgctttggca actaaactcc ctgaggtaga
    24961 actagtgatt ccccctcttc gactttgtgg agataatgct gcaatgattg gagcagcagc
    25021 acatgtggaa atgcaaaaaa gaaattttgc tagctatcag ttgaatgctg atccaagctt
    25081 ggttttatct gaataaagag gttgtgaaaa agctgccctg catcaagtaa taagaacagc
    25141 ccaggaaaaa cggcttctca tgtttttgac ctggctgttc ttattaccgc gtatgcaagc
    25201 ttttgaacgc cgtttaatca agagttcgta agcctgtcgt ttaactctga ttcacaagga
    25261 acaatttcaa aaaacagctc ctcatgttta tgaacattat gacttgtgac cgaagagttg
    25321 acaggtacac accgtttaat cgaaataggg ctgtgacacg tttttgtcaa agccctattt
    25381 tttacatact tttaatcatt attgttattt tgctattttt tacagcttat ttatcattat
    25441 ccgttcctct gattgccctc actgagtaat cgtttattgt cgaggaatat cgaataatct
    25501 agatcggatg aggacaagac gcttcatcta gttaatctaa cagtattttt tgcaaacagt
    25561 gaatattaca taactgaaac acacatagaa aatctttgag tcttgtccag tgatctaaaa
    25621 ctgccggatc tttcagaagt tttagggagg aaaataagca gtgaccctga t
//
LOCUS       DACDLM010000037        25496 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.037, whole genome shotgun sequence.
ACCESSION   DACDLM010000037 DACDLM010000000
VERSION     DACDLM010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25496
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.037"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            127..3654
                     /locus_tag="IV356_001611"
     CDS             127..3654
                     /locus_tag="IV356_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAP9015300.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3651..7373
                     /gene="addA"
                     /locus_tag="IV356_001612"
     CDS             3651..7373
                     /gene="addA"
                     /locus_tag="IV356_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HAP9015301.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7442..7783
                     /locus_tag="IV356_001613"
     CDS             7442..7783
                     /locus_tag="IV356_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP9015302.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8092..9135
                     /gene="pheS"
                     /locus_tag="IV356_001614"
     CDS             8092..9135
                     /gene="pheS"
                     /locus_tag="IV356_001614"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HAP9015303.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9140..11560
                     /locus_tag="IV356_001615"
     CDS             9140..11560
                     /locus_tag="IV356_001615"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HAP9015304.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11730..12740)
                     /gene="trpS"
                     /locus_tag="IV356_001616"
     CDS             complement(11730..12740)
                     /gene="trpS"
                     /locus_tag="IV356_001616"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HAP9015305.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            12994..13731
                     /locus_tag="IV356_001617"
     CDS             12994..13731
                     /locus_tag="IV356_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAP9015306.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13745..14560
                     /locus_tag="IV356_001618"
     CDS             13745..14560
                     /locus_tag="IV356_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAP9015307.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14573..15220
                     /locus_tag="IV356_001619"
     CDS             14573..15220
                     /locus_tag="IV356_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAP9015308.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15236..15892
                     /locus_tag="IV356_001620"
     CDS             15236..15892
                     /locus_tag="IV356_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAP9015309.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16054..16875
                     /gene="racE"
                     /locus_tag="IV356_001621"
     CDS             16054..16875
                     /gene="racE"
                     /locus_tag="IV356_001621"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HAP9015310.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16878..18233
                     /gene="rph"
                     /locus_tag="IV356_001622"
     CDS             16878..18233
                     /gene="rph"
                     /locus_tag="IV356_001622"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HAP9015311.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18234..18752
                     /locus_tag="IV356_001623"
     CDS             18234..18752
                     /locus_tag="IV356_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAP9015312.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18859..19359
                     /locus_tag="IV356_001624"
     CDS             18859..19359
                     /locus_tag="IV356_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAP9015313.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19639..20559)
                     /locus_tag="IV356_001625"
     CDS             complement(19639..20559)
                     /locus_tag="IV356_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HAP9015314.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20724..21737
                     /locus_tag="IV356_001626"
     CDS             20724..21737
                     /locus_tag="IV356_001626"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HAP9015315.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21847..22602)
                     /gene="fabI"
                     /locus_tag="IV356_001627"
     CDS             complement(21847..22602)
                     /gene="fabI"
                     /locus_tag="IV356_001627"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HAP9015316.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22822..23262
                     /gene="fabZ"
                     /locus_tag="IV356_001628"
     CDS             22822..23262
                     /gene="fabZ"
                     /locus_tag="IV356_001628"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAP9015317.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23377..24138)
                     /locus_tag="IV356_001629"
     CDS             complement(23377..24138)
                     /locus_tag="IV356_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP9015318.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24327..25421
                     /locus_tag="IV356_001630"
     CDS             24327..25421
                     /locus_tag="IV356_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAP9015319.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         8448 a         4424 c         5383 g         7241 t
ORIGIN      
        1 cgtatactta aaaaagtaga aatatcagaa ccttaaaagg atataatttg aagaatatag
       61 aacaaatgtt cagtattttt tgatataata aaggagcacc gtatcatgtg ttgaaggagg
      121 aaaagcatgt ctttacaatt tattcttgga aacgggaaaa aagatcaccg tcaagtcttg
      181 atcgacgaag catccgcttg gctcgaccag gatgcaagta accaagtatt tttccttgtt
      241 cccaactaca gcaaattcga acaggaacaa gaaattttag cggagatgcg aagaagaagc
      301 ggaaaaaaaa ctttcagcac aacaaacgtt caagtattta gtttttatcg tctggcttgg
      361 tatttgctgc aacagacaac tcttcttaca ggaaatgaat tatcagaatc aggatctgca
      421 atgatcttgc gacagatttt agaaaaaaat gaggaagaat taacaatctt tcgcggagaa
      481 atcaataaaa gagggtttat tcgtcaatta caagaactct acagtgaatt gcgtacagga
      541 aatattcaac cagaagacct gatgctttta tttggtgatt cacctaatgc agaagaccag
      601 caacttaaaa tgaaagactt gaagctgatt ttttcagctt atgacagcga attgactcaa
      661 cgtgcactaa caaatgaaga tgcactatct atactagcaa attatatgca gacacaagat
      721 ttcaacaacg tcaaatttat tgtcagtggt ttttctcgaa tcaatggtca agagtatcaa
      781 ttactgcagg caatgatgga aaaggggcaa ttggttgtcg atttattgct ggatcgtcct
      841 tatacagcgg atcttccaga agtacttacg ctctttcatg agactggaaa gctttatttc
      901 cgtctttttc aaagtgcaag agaacggaaa gtccctatat tagtggaccg atttgcacca
      961 gagcagactc gtccgacaga gcttcaactg ctgcaaacaa tgtgggaaga gacatctagc
     1021 caaaagaaag cggcagtaca caaaataggg ggacaagagc atctccattt gtgggaagct
     1081 gaaaatccaa ctgaagaagt ccgacaatta gctgttgaaa tcagacgact agtcagtgaa
     1141 gaaaactacc gttatcgtga tatccaagtg ctgacaaaaa atatgtcttt atatggaaat
     1201 atccttcggc cgatctttca agaaatggca attccttttt atatcgatga agaacaaatg
     1261 atggaaaatc atccgctgat cgaatggatc aacagtctgt tcgctcttga ccgctattct
     1321 tatcggctaa gtgatattat gcgttttttc aaaactgaat tatttctgtc gacggaagca
     1381 gaaaccgaac ttgatgaatg gaaacaagag cgagatgaat tcaggaaaaa actggacatc
     1441 actgaaaatg tagcacttgc ttacaattat caaggaactt attggactcg tgaaaaagac
     1501 tggcagtttg tggcgtatga ttttgaagca gaacagattg aagacgtaca gtatttggaa
     1561 gaacagtcaa atacgattag acgattattt cagaaagctg taccagtatt tttgaaaaaa
     1621 ataaagaaaa gcaaaacagg acaagaggcc gcaaatgttt tttatcaatt tttgatccaa
     1681 agtggcgtac agcaacaatt attgttttgg cgtaatcagg aagtagacag aggaaactta
     1741 gaagcggcaa gaaaccatga gcagacatgg ggagcgctga ttgatctgtt ggatgaatat
     1801 gtagtaattt atggtgaatc ggcttttgac tggtcactgt tccaagaaat cattacaagt
     1861 ggtctagaaa atctaagtta tggtaaaatc cctaccgcaa tcgaccaagt gcgaatcaat
     1921 cgtttggaat tagttcgacc aaatcaagct gccgtcactt ttgcattagg gttgaatgat
     1981 caagtgtttc cagaccgaaa agagacaaaa ggattgttgt ccagtgaaga acgagaagta
     2041 ttaaatcagg ccttgccaga tggacagttt ttattcgacc catcaaagga aagtatctct
     2101 tttgagcctt tccaagccta tcttgttttt ctttccggaa cagatcgatt atatcttagt
     2161 tatgcacaaa gctatgacac agatggttcg ctgaagatgt ctccttattt gcgtagaatc
     2221 acagaatatt tatctgttcc cgtcgagaga aaagagcatt tgacgatcga aagcgaccct
     2281 aattgttatg tagggactta cagaagcgga atcaatacag tcaataggat ttatcgatta
     2341 gctttagatg aaaaaaaacc tgtaccaaag cactggcaaa agctcaaaga attagtactg
     2401 aattcgtcat ggcgaaattt tgctttacag atttttgaaa gtcaggaaca tttaaatgtt
     2461 cctgtttcga tgccagaaaa aatggcggaa gagctttatg gaaaagagat ttatacttca
     2521 atttcacgta tggagaattt ttataattgt gaatacaaat acttcatgca atttggtttg
     2581 aaattgaaag aacgaactgt ttatggtcta actccagcag caactggtga tttttatcat
     2641 gaatcattgg atcgtttctt caagctactg ttttcaaacc aattatcctt agtgaatatg
     2701 tccgatgcgc agcgtagaga ctttactgaa aaagtgctgc aggaagtatt cggagaactt
     2761 cggtttgaga tattggatag ttctgcaaga atgaactata tccgctacca gttaggacag
     2821 acgattcaaa aagtgacatg ggctttgcaa aaacagagca aaaatacagg catgcatcct
     2881 cttcagacag agattctatt tggtcagatt gctggagcaa aaggtatcac aggtctggaa
     2941 ttaccgttga gtaatggtgg aaaactccat gttcgaggga aaatcgatcg aatcgatgta
     3001 gcttctgaac aagaagatac ttggctaagc gtcgttgatt acaaatctag cggacgttca
     3061 ttcgatgtca cagaagctta ttatggcatg gctatgcaat tattgacgta tctggacgta
     3121 gcattgatgg atgcggtacg tttgactgga aaggcggctg ttaaaccagc aggatcatat
     3181 tatttacatg ttcataatcc tgtattgacg gagacagatg atgtagagaa gaatacattg
     3241 aaaaaattta gttatgatgg cgtttttgtc gatgatcccg ctcttttaga agtactagat
     3301 cattcactgg aagcaaaaga acaatcactg atctatccag tgaaaaaaaa tgcgaaagat
     3361 gaataccaaa aaggtagttt cagtaaagac aaatttttca cggaagaaga actgcaacta
     3421 ttcatggcgc ataatcggga aaatatgcgg ttagctggag atgcgattac ttccggagaa
     3481 atcaaactaa atccagctta taaagataaa cagcggattg cctgcgaatt ttgtccattc
     3541 agaagcatct gtacgtttga tgtgatgctg aaagaaaata attaccaccg tctggagaaa
     3601 atagataagg aagaagcact gcgtagaata ttgaaaagga gtgaagaaga gtgaatcaaa
     3661 ttcctttaaa accgcaaaat gaacgattca cagatgatca gtggcaagcg atttttgatc
     3721 aaggagataa tctattagtc tctgcgtctg ccggatcagg taaaactaca gtgcttgttc
     3781 gaagagtgat tgaaaaacta aaaatgggtt ttgatatcga tgaattattg attgtgacat
     3841 ttactgaagc tgccgcaaga gaaatgaaag aaagaattca agaggcatta caagaatccg
     3901 tcaatagcga aagtgaccct gtacgtagac agcattttac taagcagtta gttttattgc
     3961 ccacagcgaa tatctcaacc ttacatgctt tttgcctgac agttattcga cgttattatt
     4021 acttaattga tattgatcca gtctttcgca tgttaacaga tgaaacagaa acgatcttga
     4081 tgaaggagga tgtgtgggac gagctgagag aagcacttta tgcagaaaat gatgaacgat
     4141 ttttccaatt aacaatgaat ttttctaatg atcgttcaga tgacggcttg acgaatctgg
     4201 tgttttctct ttatgagttt gcccgtgcca accctgaccc ccaaaaatgg ctagaacagt
     4261 taagcgataa ttatcgtttg cctgaggggc tagcgaaatc tcgattatat caaaaacaaa
     4321 tccgtccttt agttttggca gatatatacc aatgtgtaca gttatatgaa cagatgactc
     4381 agttagcaca aggtgaagga ttagaaaaaa tgcatgagca agtagctgga gaacaacagc
     4441 agatcaagaa tatctatgaa gcgttctcgc aagatcggtt agaagaagct tatgctggtt
     4501 tggaacaact aactttttca acttttaaga gcagtcggaa agcagaattg aaagaaattt
     4561 ccaatgaagt caagggcatg agggataaag caaaaaaact gattcagcag ataagtaaaa
     4621 gttattttcc tgtttcccca agccaaatgg aagaattaac ggacaaagca ctaccgttag
     4681 tcgaagaaat gacaaaagtc acgcaaagct tcatggacgg tttcagtatg cgtaaacggg
     4741 aaaaaggtgt gctggatttc aatgatctgg aacatttagc gttgcagatt ctcacagaaa
     4801 aaacgaaaga tgtatggctg ccaagtgaag cttcaaaaca ttatcgaaaa aaattcaaag
     4861 aagtaatggt agatgaatat caagacgtga accaattaca agaagccatt ttatactggc
     4921 taagagaacc cgatgataca aaaggaaata tgttcatggt tggggatgtc aaacaatcca
     4981 tctattcttt ccgtttagca gatcctagtt tatttatcgg gaaatacgag aatttctcaa
     5041 agaaagaagg cggacgtcga atcgttttgg ctgagaactt ccgctctaga aaagaagtcc
     5101 tttcttttac gaatcttatt tttgaacaac taatggatcc agcagtgggt caaatcaatt
     5161 atgacgaagc agccaaactg atccaaggat tttcagactt tccagagaat gaacagtttg
     5221 agccggaaat catgatctat gaaaaagaac aggaagaatc agagattgag attccgacgg
     5281 atgatatact ggaagacaaa acagaaggcg aactttttat gacaggacta aaaattcgtc
     5341 aattaattga ttcctccttt atgatttatg ataaaaaatc aaaaaaaagt cgtccgatag
     5401 agtacaaaga cattgttctc ttgacaccta caaagaagaa caacttaacg attttagaga
     5461 ttttcaaaac attggatatt ccattagaga tgaatgatgc tcaaaactat tttcaagcga
     5521 cagaaattcg cacgatgatc tcgctgctac aattaatcga taatccctat caagatattc
     5581 cgcttgcggc tgtattgcgc tcaccgatcg tgggtctgat tgaaccagaa ttagccagca
     5641 ttcgattagc taaccgtgca catacttact atgatgctgt gcttgcttat caagcatcaa
     5701 acgaagatga attagcagct aagctggaac attttggcaa gcaactagag cattggcgag
     5761 aacttgctcg ccgttcttcg atcactgact tgttatggga tatctattat gagacgggat
     5821 atctagagta tgtggtcggt ctgccagcag gggcacagag acaagccaat ctttatgcat
     5881 tggttgatcg tgccaaagct tacgagcaaa gttctttcag aggattatac cagttcgtgc
     5941 gtttcattga aaaaatgcaa gaaaaagata aagacttagc agaaccagtc atttcaatag
     6001 aagataatgc tgttcgcgtt atgacgatcc atgcaagtaa aggcttggaa ttcccagttg
     6061 tatttttgtt agatatgaca aaggagttca acttacaaga cttgcgcaat cggtatgctt
     6121 ttgaagaaaa acttggagca ggaattcgct atatggatcc tgaaacacga gtgttatatg
     6181 atacgttacc gtttcaagcc atcaaattgg caaagcaaaa caaattgttg tcggaagaaa
     6241 tgcgtaaatt gtatgtagga ttgactcggg cagaacaaaa gcttttcatt gtcggttcct
     6301 ataaaaataa agagcaaatg atccaaacgt ggtctgaagc agctgatcat gaggagttag
     6361 tttttgatcc tgcgctacgt ttgaagggca gaagcagctt gatgaattgg attggttacg
     6421 gattgatccg tcatcctgaa atgcagaaat acttagagga agaaatttcg acttctcttc
     6481 ttcaacattc aaatgcacag ttttctattt catggatgaa tcagcaatcg atcattgaac
     6541 aaagacagtt gcttgctgaa aaagaactgg ttaacttaga tcagcagatg aaagaagatg
     6601 aaactttatt agcagattcg ttacaaaaac gtctggcata tgaatatcct tatcaagctt
     6661 cttcacaaac cacaagttat caatctgtat ctgaaatcaa acgattattc gaagatccag
     6721 atgatacaca agaatcacgt ttgactctgg aaagcagtca gaacaaagca gcatcccgtc
     6781 aatttcgtta tacgcaagaa caactagcag aaccaaaatt tttgcaaaaa gatcggcaag
     6841 tgtcagcagc tgctgttgga actgctacgc atgctttgtt acaattactg ccattagaga
     6901 tgccaactac agagagtatc catcaaaaat tacaggaatt ggtaaggaaa cggttagtag
     6961 acgaaaaagt cgcgaaaaaa gtagatgttt cttctattat atggttcttt caaacagaac
     7021 ttggtcaaca gctgattgcc aacaaagaaa acgtaaaacg agaacaacct ttttccatgc
     7081 tgcttcctgc tgacgaagta tttcaagact atccaaatca agaagatgaa ctattaatcc
     7141 acggaatcgt cgatggatac ctagaagaaa aagatcatct caatatctat gattttaaaa
     7201 cagattttat tttacatccg gatgatccag cagaaataga tgcaatcgtc caaaaatatc
     7261 aaggacagct aagactttac caacaagcaa tgtcagaagc tttgaataag ccagtagaaa
     7321 atgttttcct aattttgctt cgagtgaaac aaattataaa cattaacaaa taattataat
     7381 tgagcaaact tgacttatgt tttgtaagga ttatgctata ctctgggaag aggtgagtat
     7441 gatggagcta acacagacag aattcgtttt atgccctaaa tttgaaaaaa cattctctat
     7501 tttaggaaaa aaatggaacg gattgattat cgatgtacta ctcgaaaacg gtccgcaacg
     7561 ctttgttgag cttgcggcaa aaatcccgat ggtcagtgat cgagtattag tcgaacgctt
     7621 gaaggaatta gaaaaagaag gaatagtcac tcgaaacttt gcctgtagcg aaaagagccg
     7681 ttcagaatat ctcttgactg aaaaaggagc agacttgcaa aaagcgatgc gtcaaataca
     7741 agtttggagc gaaaaatgga tcacagagga agaatgcggt tgattttgta aaaaaaatct
     7801 tgtaaactat agtccatacg aataagtaaa gaacgatgac gaaaaagagt agtttggcta
     7861 aaccagttca gggagatctg tcgcagactg aaagcagatc ctgtgtttga aaaatgaagt
     7921 tcactttccg agttcgtctg ataaaatcag accggcaatt gtcgttaacg aagtaagagt
     7981 gcggtgtaag tcatttatcc gcaaattagg atggtaacgc gaagacctcg ttccttaaca
     8041 ggaatgaggt ctttttgttt tgtatttgga atttaaagga ggaacaagca catgtctcta
     8101 caagcacaat tagagagctt gaaagaagca acgctcgtca aaatcacagc ggcacaagat
     8161 ttaaatgaat taaatcaaat acgtgttgaa acgttaggaa aaaaaggacc gatcacagaa
     8221 gtattacgtg ggatgaaaga tctaagtcca gaagagcgac caaaagtcgg aagtttcgca
     8281 aatgagatcc gagatctttt gacagaagag atcgagcgaa aaaaacaagt attagaagaa
     8341 gaagcgttaa atgcagcttt ggcaaaagaa acaatagacg tgacactacc tggtagaaaa
     8401 gtaaaacatg gtacacgtca tatcgtgaca caaatcatgg aagaaattga agatattttt
     8461 gtgggtatgg gctatcagat cgtagaagga tatgaagtag aatctgatca ttacaatttc
     8521 gaacggatga atctgccaaa agatcatcca gcaagggaca tgcaagatac tttctatatt
     8581 tcagacgaga tattgattcg gacacatact tcaccagtcc aagcacggac aatggaaaaa
     8641 catgatttct ctaagggtgc tctacgaatg atctcgccag ggaaagtctt ccgcagagat
     8701 acagatgatg cgacccacag tcatcagttc catcaaattg aagggctagt tgttgataaa
     8761 aacatcacaa tgggcgacct taaaggaaca ttagaagtcg taatgaaaaa aatgtttggg
     8821 gaagatcgtg aaattcgttt gcgtccaagt tatttcccat ttacggaacc atcagtagaa
     8881 gtagatgtca gctgtttcaa atgtggtggt gccggttgta acgtatgtaa atacactgga
     8941 tggatcgaaa ttttaggagc tggcatggta cacccgaatg tgttgaagat gtcaggaatc
     9001 gatccagaag aatattcagg ctttgctttc ggccttggac cagaccgcgt agctatgttg
     9061 cggtatggag tgaatgatat ccgtaatttc tatcaaaatg acttacgttt cttaagtcag
     9121 ttcaaggggg agtaagaaaa tgttagtttc atataaatgg ctcaatcgtt atgtagattt
     9181 atcgaatgta acaccaaaag aattagcgga taagatgtct gtgacaggaa tcgaagtaga
     9241 gggagtaacg gttccagaag aaggcttgaa aaaaatcgtt gtcggtgaag tcaaggaatg
     9301 cgtaccacat ccagattctg atcacctttc tatttgtcaa gtcgatattg gcgaagacga
     9361 actgtctcaa atcgtttgtg gagcgcctaa tgtgaaggtt ggaatcaaag tgattgttgc
     9421 acttcctaac tcacgtatcg ctggtaatgt aaaaatcaaa aaaggaaaaa tgcgtggcca
     9481 agtatcaaat ggcatgattt gctcattaca agaaattggc tattcagata gtgttatacc
     9541 gaaagaatac gctgaaggta tctattatat gccacaagaa gctgtaaatg gcgatccagt
     9601 ttttccttat ttggatatgg atgattcgat tattgaatta tctatcacac cgaatcgtgc
     9661 ggatgcattg tcaatgcgtg gcgtagctta tgaagttggg gcaatttatc gtcagactcc
     9721 tacattcgat gacgaaaagc tggtagaatc ctcacgtcct gctagcgata aaattcaagt
     9781 ggaagttgaa gataaagaag cagttcctgc ttatcaaatc agaatcattg aaggagtaag
     9841 aatccagcca agtcctcaat ggctgcaaaa tcttttgatg aacgaaggca ttcgtccaat
     9901 caacaatgta gtagatgtga cgaactatat tttgctttta ttcggacaac cactacatgc
     9961 atttgactac gacaaattga aatcaaaaga gatctttgtc cgccgtgcaa aagaaaatga
    10021 aacattagta acactagatg gagaatctcg ggaattgaca actgacaatc tcgtcattac
    10081 taacggcaaa gaaccagttg ctttagctgg tgtcatggga gggttagact cagagatcac
    10141 gaatgaaaca acaacagttg cactagaatc tgctttattt gatccaattt cgattcgtcg
    10201 tacagcaaaa caatttaatt tgcgtagtga atcctctgca cgttttgaaa aaggaatcaa
    10261 ccatgcgact gttggagaag ccagtgaggt tgctgcagca atgatcgttt ctcttgcggg
    10321 tggggaagtt ctacaaggcg cggtcaaagg ctcagagatc aaagcagaag acgtatcagt
    10381 gaagatttca cttgaacgca tcaatcaata tttaggaaca tctcttgtcg ttaaagaagt
    10441 aaatgagatt tttgaagcac ttggatttag ctatgaagaa aaggagtatg tttattccgt
    10501 agtagtacca ccaagacgct gggatatcca aatcgaagca gatattatcg aagaagttgc
    10561 tcgtatttat ggatacgacc agttgccatc tacacttcca agtggagaaa cggttgctgg
    10621 aagcttgtca aaagaacaag aaactactcg taaaattcgt acaatctttg aaggaagcgg
    10681 attgagcgaa gcaatcagtt atgcattgac aacagaagaa aaatcaagac agtttgttat
    10741 aaatgaaagt aatattacac gtttggactg gccaatgagc gaagaacgtt ctgtattacg
    10801 aatgaatttg atcagcggac tattagatga tatcagttat aacactgccc gaaaaaatac
    10861 agagattgct ttatatgaaa ttggtcgggt gttcttccaa gaaaatgatc cacgtacaca
    10921 tctgccgcaa gaagtaaaac atgcagcaat cgctatttct ggtatttggg aagaaaaaga
    10981 ttggcagacg aaagctcaaa atgtagactt tttcaccatc aagggtcttt tagaaaactt
    11041 atttgaacaa ctaggcatca ctgaagatgt ccattatcaa acagtgacag aaatgaagga
    11101 aatgcatcct ggaagaactg ctgcgattta ccttggcgaa aaatttattg gttttgtcgg
    11161 tcaagtgcat ccaacgatta caaaaagtta tgatattcca gaaacatatg ttgctgagtt
    11221 tgatttatct gctatagtgg aagctgctca aaaagggatc gttttcgaag cagtgacaaa
    11281 attcccagca gtcagccggg acatcgcttt gcttgtaaaa gaaactgtga caaatcagga
    11341 attaacagaa gttatccgtt ctgctgccgg aagattttta acagatatcc aattatttga
    11401 tgtctatcaa ggagaaaaca ttgaaaaagg acataaatcc atggcgtata gcctgacatt
    11461 cgtcaaccca gaagcaacat tgacagatga agaaatcaat aaagcaatgg aaaaagtcga
    11521 aaaagcgttg gtagaaaacc tagaggcaag tattcgctaa gaaggaaaat atagtaagta
    11581 acgatcaagt agcttttgaa gaccatacat ttgaaaaaaa gatgtgacac aacttcgtca
    11641 catctctttt tttgatttta aaaaaggaat agcacagaga cgagataaaa aaacaggcct
    11701 ttacagcctg cttttttaga gtaaatgaat taatggaagt aattgattcc cattgctgat
    11761 tttacttcag aaagtgtttg tgcagctact ttagcagctt cttcactacc tttacgtaag
    11821 atttccataa cagctgaagg atctttttcc aattcttctc ggcgcgcacg gatcggtgca
    11881 aattcagctt ccaatacatc aatgaggtat cgtttgatct ttacatcacc aagtccgccg
    11941 cggcggtaat gagctttcat ttcttcaatt gcttctttat ctgttccgaa tacatccaag
    12001 taggtgaaga ccatattccc ttctacttgt ccaggatctt gtacatggat gtggtttgga
    12061 tcagtataca tactcatgac ttttttctgt aagacatcgg caggatcgga gatataaata
    12121 ccgtttccta acgatttact cattttgcca tttccatcga ttccaggtaa tctacccatt
    12181 ccttttggtg ggaatacgcc ttttggttcc accaagactt caccatatgt atgattgaag
    12241 ctttgtacga tttcctgtgt ctgctctagc attggttttt gatcctcacc aacaggtaca
    12301 agattcgctt tgaatgcagt gatatctgct gcttgagaaa caggatagat aaagaatcct
    12361 gtaggcacgc tttcaccgaa ttttttttgt tcgatttctg ttttgacagt cggattgcgc
    12421 cgaacgcgtc ctacgctgac taagttcaaa taatacatgg ttaattcagc taattccgga
    12481 atttgtgatt ggataaataa agtagatttt gcaggatcta atcccacggc taaatagtct
    12541 aaagcaactt gcaagacatt tgatgaaacc ttctcaggat ttttagcatt atctgtcagt
    12601 gcttgcatgt cagcaatcat gacaaacagt tggttgtctt catctgcctg catagccact
    12661 cgggttttta gagaaccgac gtaatgccct aaatgcagct tcccagttgg tcgatctccc
    12721 gttaaaataa tatttttcaa aaaagacacc tctttacgat ttgtaagtct gagcacttaa
    12781 tatcttaccg tttttcctga aaagaaacaa cagttcctaa ggaaaaaaca aggaaagagg
    12841 ataaaataac taatagatta gaaatggaag aaatatttat gggagaataa acgttctaag
    12901 aaactttaca aattactaaa ctatcagata taatgtattt tattatacat ctttaaaaga
    12961 aatcttacta aataataatg ggagtgtaat tctatggcaa tgattaaatt tgatcacgtg
    13021 gataaatatt atggcaagtt ccacgcatta aaaaatatca atctcgaatt cgagaaagga
    13081 gaagttgtcg ttgtcattgg tccttctggt tcaggaaaga gcacgatgct tcgctgtatc
    13141 aatggattag agacgatctc ttcaggtaag ctgctgatta atgatactga cttgcatgat
    13201 aaaaagacaa aactgacaga agtccgaaaa aacatcggca tggttttcca acatttcaat
    13261 ttgtacccaa ataaaactgt tctggaaaac atcaaattag caccaatcaa agtgttgaag
    13321 caagaccagg caactgcagt caaaaacgcg gagaaatttt tgaaaactgt caatatgtta
    13381 gataagaaag attcttatcc ttccatgtta tccgggggac aacagcaacg ggtggcaatc
    13441 gccagaggtt tagcgatgaa tcctgagatg ctgctgtttg atgaacctac ttctgctttg
    13501 gatccggaaa tgattggtga tgtattagac gttatgaaaa aattggctca tgacggtatg
    13561 tcaatgattg tcgtgacaca tgaaatgggc tttgccaaag aagtggcgga tcgtgttatc
    13621 ttcatggctg atggagaagt attggaagac agcagaaatg tgagagactt tttcgaaaat
    13681 ccaaatgaag tccgagcaca gcaatttatc agtaaagtta tcaatcattg ataggaggaa
    13741 aaagatgcgc aggttaaaaa aaatacgcct gattttcctt ttaggcattg cttttcttgc
    13801 actagccgga tgtaaaggaa atgggttggc aaatgaagat attttagagc gaagcaaatc
    13861 taccaatgaa atcatctggg gtgtcaagta tgatactcga ttatttggaa tgatggatat
    13921 tgagagcaga actgtacaag gatttgatgt agatattgca aaagcaatca ctaaaaagat
    13981 ccttggtgac aatggaaaaa cagaatttgt tgaagtcact tctaaaactc ggattccatt
    14041 attgaaaaac ggaaatatcg atgcaattat tgcaacgatg acgatcacag atgaacgaaa
    14101 aaaacaggtt gacttttcag atgtctattt cgatgctggc caagctttgt tggtaaagaa
    14161 aggaagccaa atcaaaagtg tagatgattt gaatgcttct acaacggttc tagcagtcaa
    14221 aggttctaca tcggctgcga atatccgaca gcatgcacca gatgcaaaaa ttttagaatt
    14281 agaaaactat gcagaagcat ttactgcttt acaatctggt cagggagacg cgatgactac
    14341 ggataatgcg attttgttag ggattgcaga tgaaaatcca gagtatgagt tagttggtgg
    14401 aacgtttact aatgagcctt acgggattgc gatcaacaaa gggcaagaaa acttcttgaa
    14461 agctgttaac caagcgctag aggaaatgca tgcagatggc acatacgata aaatctatca
    14521 aaaatggttt ccaaatgaaa ctgaaggaaa agtagagtaa gggggagagg caatgagcga
    14581 attgatacaa acttatggac caatctttgt cgacgggttc aagatcacat tgttttcgag
    14641 tgtcttagca cttgtgttta gtttgattat cggaacgtta atggcaatct tccaattatc
    14701 aaagaataaa gtagtgagcg ccttagcaaa ggcatatgta gaatttttta gaaacattcc
    14761 attattaatc atcgtgatgt ttttttatgt tgtcgtaccg atttattggt ttaatctaga
    14821 tggattccaa gcaggtacga ttggattaac gatctataca tctgctttta ttgctgaaac
    14881 agtacgttca gggattcaaa ccgtaccaaa aggtcaaaca gaagcaggac tatcttctgg
    14941 ttttacctat tcagaaatca tgcgttatat tgttttaccg caagcattca aaatcgttat
    15001 cccgccatta ggcaaccaat ttatcaacct cgtaaaaaac tcatctattt tagcaatcgt
    15061 agctggttta gatttgatgt atcaaggaga cttgatcgct agtgaaacat tcaatacctt
    15121 cgatacgtat atcatcgttg ggttatttta cttagttatc acgctaccgt tatcttactt
    15181 aatggtttat cttgagaaaa aatgggcggt tcgttcatag aaggagggga aatacatgga
    15241 ttttagcggc gctttttcat ggatgaatat ccgtttttta ttggaaggat taaaggttac
    15301 tgttgaagtt tcattgtttt cgatcatttt tagtttcttg atcggtggtc tgacaggtgt
    15361 gattcgtttt gcgaatatcc ctttcttttc caaaatcctt ggtgtagtga ttgatattat
    15421 acggaatctt ccattattat tgatcatttt cttcacttac tttgccttac ctcaaatcgg
    15481 cattcagatg aacatcttct ggtccgctgt cgcagcatta acgatttttg agtcagctat
    15541 gttgtcggaa attttccgag ctggactcaa tgctgttcca aaaggacaga tggaagcagg
    15601 attatcaacg ggactgactt atgtagaatc gatgcgaacg atcgtgttac cgcaagcatt
    15661 taaatcaatg atcccggcaa ttgtgagcca attgatttca ctgatcaaag atacttcatt
    15721 agcagtaatc atttctttac ctgaactttc tcatcaggca cgtattattt atggacagaa
    15781 caccaattat gtgcttccga tgttcatcat catgacactt atgtacttcg tggtatgtta
    15841 cgcgctttct ctgctttccg gttacttgga aaagagacgg tacagttatt aatagatgat
    15901 tcttttagcg gttgtggcaa actaaagtca caaccgcttt tcctctttcc attcgaaaaa
    15961 aagagatttc gattgtttta agcaagtaag agcacttgaa aattcacgct aaaaagtaca
    16021 caatagggag gatagaattt attgaaaaaa aggatgatac gattgacaga taatcgccct
    16081 atcggattta ttgattcagg tgtcggcggc ttgactgtag taaaagaagc cctgaaacaa
    16141 ttaccgaatg aaaatatttt atttgtagga gacacagcac gctgcccata tggccctaga
    16201 cccgcggaac aggtaatcca gtatacttgg gaaatgacgg attatctggt ggagcaagga
    16261 atcaagatgc tggtgatcgc ctgcaatacc gcaactgcgg tggctttaga agaaatcaaa
    16321 gctgctcttt ctattccagt catcggtgtg atccttcccg gtactagagc ggcagtaaaa
    16381 aaaacacaaa ataaacaagt tggcattatc ggtacgattg gtacggtaaa aagtcaagct
    16441 tatgaaaaag cactgaaaga gaaagtacca gaattgactg tgacaagtct tgcttgtccc
    16501 aaatttgttt cagttgtcga aagtaatgaa taccattcat cggtggcgaa aaaaattgtg
    16561 gcagaaacat tagctccttt aaccactaaa aaaatcgata cattgatttt gggatgcacc
    16621 cattatccat tattacgccc catcattcaa aatgtaatgg gagaaaatgt tcaactgatc
    16681 gattctggag cagaaacagt aggtgaagta tctatgctgt tagattattt caatttgagc
    16741 aattcaccgc aaaatggtcg gacattatgc cagttttata caactggctc tgccaaactt
    16801 ttcgaggaaa tagctgaaga ctggcttgga atcggacact taaatgtaga acatatcgaa
    16861 ttgggaggaa aataaggatg cgtcatgacg ggagaaaagc ccaagagctt cgcaaactgg
    16921 agcttcaaac aaatgttttc aaatatccag aaggatcggt agtgatccgt tttggtgata
    16981 caacagttat ttgttctgca acaatagaaa attctgttcc cccttttttg agagaaacag
    17041 gaacaggatg ggtgacagca gaatatagta tgctgcctcg agcaacgagt acgagaaatc
    17101 gtagagaaag cagcaaaggg aaactttctg gtagaacaat ggaaatccag cgtcttattg
    17161 gtcgttcctt gcgtgcagta gtagacttgg aaaaattagg agaacgtagt atcatcgtag
    17221 actgcgatgt gatccaagcg gatggcggta ctagaacagc aagtatcact ggggcatttg
    17281 tggcattgaa attagccatt gaaaaacttt taagagaaaa agaattgtca gaagatccaa
    17341 taaaagaaca tcttgctgca gttagcgtag gaatcttacc agatgggact tgcgtcacag
    17401 atttggatta ccaagaagat tccgcagcac ttgtagacat gaatcttgta atgacagaat
    17461 ctggaaaatt cgtggagatt caaggaactg gagaagaagc aacgtttgat ggtgaacagt
    17521 tgaatgaaat gctctttttt ggaaaaaacg cgattgaaga tttgatcaaa gagcaaaaac
    17581 atgctttgct aacagagttt gctcaaaatg atgagcggat agaagaaaca aaaacaatca
    17641 tcattgcgac aagaaatcca ggaaaagcag aagagtttcg aaatatgttc aaagaagcgg
    17701 gatatcatgt aaaaacatta cttgactatc ctgaattgcc agatgtggaa gaaactggca
    17761 gcacatttga agaaaatgcc cgattaaaag cagaaacgat tgcacaattg cttgatcagc
    17821 cagtcttagc agatgattca ggtttgaaag tggatgcttt aggcggtatg ccaggaatct
    17881 attctgcacg ttttgcaggg gaacaaaaaa gtgatgcggg gaataacgcc aaattattat
    17941 atgaattgac agatgtgccg gatgaaaaaa gaacagcaca attccattgt acgttagtat
    18001 tcgcggcacc caaaaaagac agccttgtag tagaagcgga atggcccggt cgagtagccc
    18061 gtataccatc tggcgaaaat ggctttgggt atgatccttt atttatccca gaaggtaaga
    18121 aacaaacagc agcagaatta tcgagcgaag aaaaaaacaa gatcagtcat cgggctcaag
    18181 caatgaaaaa attgagtgcc gagtggaaac aatggctgga aggagagaga tagatgcggt
    18241 atttagtagt aagtgataat catggagaca gagatatcct cgttgactta gtagatcgtt
    18301 atcgttctga agtggatatc tttttccatt gtggtgattc ggaattagaa gcttctgacc
    18361 cattatggga tacattccaa gtggttcaag gtaattgtga ttatggacca ggattcgaac
    18421 agaaaaaagt gatccaaact ggtcaggata cagtattcat gactcacggt catttatcga
    18481 atgtccgatt tggtttgaca cagttagcaa tcgaagctcg agctgcaact gccgatatgg
    18541 tgttttttgg tcatacccat caaataggct gtgagatgga tcagaaaatc ctgtttttga
    18601 atcctggtag catttctcag cctagaggcc cgatccaaat cccatcatat gctcttatcg
    18661 aaagtttaga tgaccaaatt tctgttcaat actataaccg tgcccatcag gcagttgaag
    18721 agttggcctt ttctttttcg agagagcgct gaataaaaaa actctaattt ttaataaaaa
    18781 taagctttat tttatgaatt ttgcatccgg tttcggtaaa atagtagtgt tgaatgaaat
    18841 agaaatggag gccatcagat gattggacct atagtaagag aaatgctgct ggaaaatcag
    18901 gaaacgtttt tgattcctgc agaaaatgtg gcaaatgtta tgtatcatca tccattgtcc
    18961 catggtttac ttgtgttatc gaaggtcggt tattccaaaa ttcctgtatt aggaaaagat
    19021 gatcactttg taggactagt aagtttatca gatgtggtca ataaaatgat tgacttgcaa
    19081 acaatcagca tggacccgtt agaaggacta acggttgctg atgtgacaga aacagatgtt
    19141 ccgacaattg atgaaaattg ggaactagaa gaagtactcc atttgttagt cgattcgcct
    19201 tttttaccgg ttgtcacaga agatcggatt ttcaaaggaa tcattacaag aaaagagctg
    19261 cttaaagccg taaacttcat ggtgcatgaa ttagaacgtc gtaatatatt gtctccgaaa
    19321 atcgaagaat taaaagaaca aatcgatatc gtgagctaaa gaacgagaaa ctaaaagata
    19381 atcaaaaaat aagtagaaaa aacagcgtac cagttttgac tttatcttga aaaagaggct
    19441 gggacaaaag cgtttaactc caagaaataa gaaggaattc acgaaaattg cttttcaaat
    19501 ttttgtgaat ttcagcttat ttccgaagga gttgcttctg cttccgccgt ttatacgtgt
    19561 ttagagcgtg ggacaaaagt gttctttact tttgtcccac gctcttttta gtgagattcg
    19621 ttgcatcgtt tgtccaaatt attttccgac agcaattgga ctgttcggaa tcgtgaaacc
    19681 agaagctgtc aattctttga cataggagct caagaactct tcttttaagg catattgttt
    19741 tccgttcaat gcgtagcaga ccgtacgaat cgcaaaattg ctgtttccaa gatccactaa
    19801 tccaaagata gaaggttcag tttggagctc ttcttggtat ttttcagcta atgtacgatt
    19861 tactcgatca atgatctcat agattttgtc atatccttct tcaggaacaa tccgaatatc
    19921 taaaagtact tgcatatttg cacgagagag attgctgatc gtggtgatgt ttcgattcgg
    19981 gatgaaatgg acagtaccat ccgttgcttt cagctgaagg gtacggatac caacagatac
    20041 gacggttcct tcaatcgtta agtttgctag cttgatgtag tccccaacat ccatctgttg
    20101 ttccatgata ataaaaaatc cggtaataac atcactcatg aacccttggg caccaagacc
    20161 gattgccaca cctgcaattc cggcaccagc caaaagtgat ccgatcggca caccgatagc
    20221 agataaaatt gcatagataa aaaagaaacc aagggtataa tgaaaaatag tatttaaaag
    20281 actatgtaaa gtctttaagc ggctctcgtt tagaatggct tttttagaat actgattaaa
    20341 agacttatca atcagatatt ttcccacacg gtgaagaatc caaaaaagga cgatcaaaaa
    20401 aatcagatat aaactttttt ggataaaggc agccaaaatg gcgtcccaat caatcccgtc
    20461 ccaaaaccgc tgaaacgcat ttactttgct gacagcttga tctgtcaatg tctcgccaga
    20521 agagtctgtc gtaccggcag ttgctaataa tgaaaacata aaatcctctt ttctaaaatt
    20581 tgattctttc tgtattgtac caagaagttt tcaaaaaagg aaatagcaaa aataactata
    20641 atgaaggaaa aaagctgaaa ataaaatgac aaataatatg gataatgata aaatgtggag
    20701 aaaataacga aggtggtaag tatatgcaaa tcgattggaa caatctaggt ttttcttata
    20761 tcaaaactcc ttggcgtttt attgccaaat ggaaagacgg acaatgggaa gaaggagaat
    20821 tgacagaaga taattacctg acgattcatg aaggctctcc agcgcttcat tatggtcagc
    20881 aatgttttga aggtctaaaa gcttatcgtc gaaaagacgg caaggtcaat ctctttcgac
    20941 ctgaacaaaa tagtcgacgg atgaatcaaa gtgctagacg attgctgatg ccaatggtcc
    21001 ctgaaaagat gttcgttgat gctgtcaagc aagtggtaaa agcaaatgaa gattttgtgc
    21061 cgccctatgg aacaggcgct acattatact tgcgcccttt actgattggg gtcggtgaaa
    21121 acattggtgt ccatccagct ccagaatatt tatttgtcgt cttctgtacg ccagtaggag
    21181 cgtatttcaa aggtggacta aaaccaacga attttattgt atctgattac gatcgtgctg
    21241 ctcctaaggg gactggtgca gcaaaagtcg gcggaaatta cgcagcgagt ttacttccag
    21301 gaacagaagc aaaagaactg gattactcag attgtgttta tcttgatcca gccacacata
    21361 cgaaaatcga agaagtaggt gcagcaaatt tctttggaat tacaaaagac ggaaaattca
    21421 tcactccgca atcgccctct atcttaccaa gtatcacgaa atattccttg ttgcagttag
    21481 ctgaagaacg actaggactg caagcaattg aaggagatat tttcattgat gatctagatc
    21541 aatttgcaga agctggtgca tgtggtacag cggctgttat ttctccaatc ggtgggattt
    21601 atcacaataa caatcttcat gtattttata gtgaaacgga agtaggacca gtaacaaaac
    21661 ggttgtatga tgaattgaca ggtattcaat ttggagacat agaagcacca gaaggctgga
    21721 ttgaagtcgt ggaataattt caaagtaatg agttgaaaaa aacgtaaaaa gaaaaaatca
    21781 ggaagagact ttaaaaagtt ttttcctgat ttttatatgt tttactttaa agaatgcaac
    21841 aaaagtttat gaaagatgga cacctttgtc aacgtagata atatcaccga tgattccgct
    21901 ggaaagtggg ctgattaaga aagcacaagc attaccgact tcttcgatcg tcacaccttg
    21961 ctgatcaggc gtacgagatt cagataactg gatcagtttt tgatagtctt taacacctgt
    22021 gacagctaat gttttgattg ccccagctga gattccattg acccgaattc ctttaggcga
    22081 gaactcagct gccaaataac ggatagcagc ttcaagagaa gctttcgcaa tacccatcat
    22141 gttataattc gggattgcgc gttctgaacc tagataagtc atgctaacga tcccgctgtt
    22201 tggtgcaaga aacggttgtg cgtattttga tacagcaatt aaagagtagc tgctgatatc
    22261 ttgagctaat tgatagccgt ctctggaaat atcagacaca tttccggaca attcttcttt
    22321 gttggcgtaa gcaactgcat ggacaaggcc gtggatctcc ccagcatatt caccgatggc
    22381 attcattgct ttttcgatgc tttcgtcgct agaaacatca cattctacag tgaatgcttc
    22441 ttcgccgacc aatttgacta atgatttttt cattcgttca ttttggtaag tatagataat
    22501 ttctgcccct tgtttcaaca ttgcttcagc acaaccccaa gcaatgcttt ttttgttagc
    22561 gacgcccata atgacgattt tttttccttc tagaaatgac ataatgactc tcctttgttt
    22621 ctgataaaaa tttgatagtc gtaaaaaaat agagaataat agctaaaata acttcttgat
    22681 ttcttaatta ttagtcaaaa tgttttgatt gtcaaactat tttttcttaa attaaaaaaa
    22741 gattgctaaa tatttaggaa tatgatactt tgatagtcaa agtaatgaaa atggcaattg
    22801 cctgaaagaa ggagtttaat tatgtcttac gtattatctg ctactgaagt aatggaattg
    22861 attcctaatc gttatcctat ttgttatatt gattatgtag atactttaga accaggaaaa
    22921 aagatcgttg cgacaaaaaa tgtaacaatc aatgaagatt ttttccaagg tcactttcct
    22981 gacaatccag tgatgccggg tgcgttgatt ctagaaacac tggcacaagc aggttcgata
    23041 cttatcctaa aatcagaaga gtttctagga aaaagagctt atatcggtgg gatcaataag
    23101 gccaaattcc gtcaaaaagt tgttccagga gatgtgctga aatgtcattt tgaaatcacc
    23161 aaaatgaagg gatcagtcgg tacagcgtta tctgcagcat atgtagatga taaaaaagtc
    23221 tgtgagtgcg agttcacgtt catcgtcaac caaaatgctt gactataaaa cctgatatag
    23281 caaaacaaaa ggaagcttac ttgcttttta tgtaaaaaga agacgcctga atcctagcat
    23341 acgttgtcat ctatgcagga ttcagacgtt atttttttat ttttgttttg cttcttgcag
    23401 tatattgatt ttatcgattt ttacttcttc ttttggtttg tctgaactat ctgtttcgat
    23461 atttgcaata gcatccacga catccattcc ttcaatcact tggccgaaga cagtataatg
    23521 gccatctagt gaaggataac cgccgttttt ataagcgtcg atgattgctt gaggatagtc
    23581 gtcttttaaa agaccatcat gcatatcatc tgtattttga acgataaaga actggctgcc
    23641 gttactgtta ggatcttgtg agcgagccat agataacgca cctcttatat tataaaggtg
    23701 gttgttgatc tctgtttcaa atccttctcc ccaaatgctt tcccctccag tgccatcgcc
    23761 tttaggatcg ccaccttgga tcatgaaatc tttgatgacg cgatggaaag tcagtccgtt
    23821 gtagtaaccg tcttttgcat gtgtcataaa gttttcaacc gcttttggtg cgtgttcggg
    23881 aaataatttg attttgattg tgcctttatt cgtcaccatt tcgaccagat cttcattttc
    23941 ggcgacatct ttcgtcaatt gtggtaattc caatgcgttc aaatcgacgc tactggcagt
    24001 cgtgctttcc gcagtagatg tactttttga actttctgta gacgaactag aagaagtcgt
    24061 gttgtttgca gaacaaccag cagcaaacag caatgctgct gctaaactaa tacttaaaat
    24121 aactttattt ttcttcataa ctgttccttt ccaatttact attttgttat ctttaatgat
    24181 aacaaaatag agggaaaata cctacttaaa ttattggaat ttatcattta ttttaaaaga
    24241 aaaagaaaag gtgtagacca tttactttgt gtttgctata atgtaagtgg atacaaaaac
    24301 gaaaagatgc aggaggaaat ggtaatatgg gaaaattagg aatctcgatt tatccagaac
    24361 ggtcaacatt tgaaaaggac aaagcgtact tggatttagc tcataagtat gggtataaac
    24421 gggtttttac cagtttgctg cagatcaatg atgataaaga aaaagttctt tcagaattta
    24481 aagaagtagt tgattacgcg aatagcctag gcatggaagt aatggttgat atcaatccag
    24541 cgttatttga acagttggag atttcttacg atgacttatc ttttttccat aagatgggtg
    24601 cctacggggt ccgcttagat atcggattca caggagcaga agaagcaaaa atgacgcgca
    24661 atccttttgg tatcaaaatc gagatcaata tgagttcggg cacgaattac gttgacaaca
    24721 tcatgagtta ttcgccaaac acggataatt tattaggttc tcataatttt tatcctcatc
    24781 gatactctgg tttaggatac gaacactttg ttttttgttc agaaaaattc agaaaatata
    24841 atttgaatac gatggcattc gtcaattcgc aatctgctga gtttggccct tggcctacgc
    24901 aagatggctt gtgcacgctg gaagaccacc gagatcttga aattgcgaca caagtgaagc
    24961 atttaatcct tacaggattg attgatgata tttctattgg aaatgcgtac gcaagtgaag
    25021 aagaattgaa agaaatggca gaagcattta acgcggatta tccaacattg aaagtagata
    25081 cggaagaagg tattacagaa aacgaacgaa tctgcttgtt tgataacctt catagttatc
    25141 gaggggatcg ctcagaatat atccttcgtt caacgatgac tcgtgtatac tacaaagata
    25201 aagatttccc gcctcataat acgcgagata tgcatcatgg ggatgtactg attgacaatg
    25261 aagggtacgg tcaatacaaa ggagaaacac aaatcgcctt gaaggatatg aaaaacgacg
    25321 gacgtgtcaa tgttgtagga agaatctccg atgacgaatt attcctcctt gactttttga
    25381 aaccatggtc aagctttaaa ttaattgaaa ataaaaaata gataattagt tattgcagaa
    25441 ataatccgct agaaatagcc agttatttct gcttttttat tttgtttttt tatagg
//
LOCUS       DACDLM010000038        25219 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.038, whole genome shotgun sequence.
ACCESSION   DACDLM010000038 DACDLM010000000
VERSION     DACDLM010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.038"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(56..643)
                     /locus_tag="IV356_001631"
     CDS             complement(56..643)
                     /locus_tag="IV356_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015320.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            818..2140
                     /locus_tag="IV356_001632"
     CDS             818..2140
                     /locus_tag="IV356_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP9015321.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            2295..3071
                     /locus_tag="IV356_001633"
     CDS             2295..3071
                     /locus_tag="IV356_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAP9015322.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            3064..3633
                     /gene="rnmV"
                     /locus_tag="IV356_001634"
     CDS             3064..3633
                     /gene="rnmV"
                     /locus_tag="IV356_001634"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HAP9015323.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            3626..4510
                     /gene="rsmA"
                     /locus_tag="IV356_001635"
     CDS             3626..4510
                     /gene="rsmA"
                     /locus_tag="IV356_001635"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HAP9015324.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            4961..5590
                     /locus_tag="IV356_001636"
     CDS             4961..5590
                     /locus_tag="IV356_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015325.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(5714..6823)
                     /gene="ugpC"
                     /locus_tag="IV356_001637"
     CDS             complement(5714..6823)
                     /gene="ugpC"
                     /locus_tag="IV356_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HAP9015326.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            7032..7454
                     /gene="mgsA"
                     /locus_tag="IV356_001638"
     CDS             7032..7454
                     /gene="mgsA"
                     /locus_tag="IV356_001638"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HAP9015327.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            7777..8313
                     /locus_tag="IV356_001639"
     CDS             7777..8313
                     /locus_tag="IV356_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAP9015328.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(8353..10116)
                     /locus_tag="IV356_001640"
     CDS             complement(8353..10116)
                     /locus_tag="IV356_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9015329.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(10119..11834)
                     /locus_tag="IV356_001641"
     CDS             complement(10119..11834)
                     /locus_tag="IV356_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9015330.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(12613..12837)
                     /locus_tag="IV356_001642"
     CDS             complement(12613..12837)
                     /locus_tag="IV356_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015331.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            13037..15805
                     /locus_tag="IV356_001643"
     CDS             13037..15805
                     /locus_tag="IV356_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP9015332.1"
                     /translation="MLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNTVSH
                     YLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQPKDL
                     FSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLHDLL
                     EDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLDEVH
                     RLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRIPIR
                     IELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGELKNI
                     VKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLMEKQ
                     QPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHELLVY
                     WTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELEQQV
                     SQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIAAHG
                     YATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILVDMG
                     SLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPEWRL
                     LYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNSDPL
                     FSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQRII
                     RNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLIERL
                     IRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSEDTE
                     FLSIEEEF"
     gene            15886..16305
                     /locus_tag="IV356_001644"
     CDS             15886..16305
                     /locus_tag="IV356_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HAP9015333.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            16317..16787
                     /locus_tag="IV356_001645"
     CDS             16317..16787
                     /locus_tag="IV356_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP9015334.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            16804..17583
                     /locus_tag="IV356_001646"
     CDS             16804..17583
                     /locus_tag="IV356_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP9015335.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            17570..18391
                     /locus_tag="IV356_001647"
     CDS             17570..18391
                     /locus_tag="IV356_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP9015336.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            18408..19457
                     /locus_tag="IV356_001648"
     CDS             18408..19457
                     /locus_tag="IV356_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP9015337.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            19470..20474
                     /locus_tag="IV356_001649"
     CDS             19470..20474
                     /locus_tag="IV356_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP9015338.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            21107..22126
                     /locus_tag="IV356_001650"
     CDS             21107..22126
                     /locus_tag="IV356_001650"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAP9015339.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            22169..23050
                     /gene="galU"
                     /locus_tag="IV356_001651"
     CDS             22169..23050
                     /gene="galU"
                     /locus_tag="IV356_001651"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAP9015340.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            23350..23727
                     /locus_tag="IV356_001652"
     CDS             23350..23727
                     /locus_tag="IV356_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015341.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            24333..24947
                     /locus_tag="IV356_001653"
     CDS             24333..24947
                     /locus_tag="IV356_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP9015342.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
BASE COUNT         8180 a         4360 c         5202 g         7477 t
ORIGIN      
        1 aacaatcatc ggctttgact tcgatgattg ttttctttat tttgtaaaaa tcctatcact
       61 tgattttatg gtaacctttt atttttgtct tcaaacggct tggtaagaga gcagtaagca
      121 gtgcaaatgg gatcgaaaag acataccaga aaatcgtacg tccgatacca taatgttgat
      181 agagctttgt caacatcacg tgtaacaaga tcaaccctaa aagcaaggag ccagctataa
      241 accaatgatt atcccaatgc atgacttcac taagtgccat cactccaaaa ggatagaaat
      301 aaaaatagat cccgactaag gtcatccgcc agttctttgt aaatgttccg atattcaata
      361 aaaagaaaat cgctgaaagc aaaataccga taggcggaaa aagcccaacc aaaaaggaat
      421 acaacatccc ccacaagatc atcacaggac ctttgatcaa tgcaacgatt gcgatgaaca
      481 aagtcagcaa tattagtttt tgtgataacg ttgcaacagt cattaatcca aataaaatta
      541 atgtgaacca atgccaatgg gactgctgtt gttctttacg ggaaaaatcg acccggttgg
      601 ataaataatc tgctaatttc ggataagaac gcttaaaatc cataaactgt tcctccttcg
      661 tggaaaaggt aggtttagta tacgaaaaat aaaaaagaaa tacatccgtc ttaagaggga
      721 gtttttcact gaaagtggag aaaaaagaat ggtaaattaa aatattctca gttatactga
      781 aaattatacc aaatttcaaa gaagaaagag gatgggaatg aaaggcaaac taaaacgaga
      841 aatcaatctg tttggcgcat tagctaccgt tatgggaacc gtgatcggtg caggcgtctt
      901 cttcaaaact gctgctgtta ctgctagtac tcagtctaca agtttgacat tgctagcttg
      961 gcttttgggt ggtttcttaa cgatctgtgc tggattgaca gtggctgaat tagctacagc
     1021 aatcccggaa actggtggag ctgtaaaata tattgaagct gcgtatggaa aattgcccag
     1081 ctttttatta ggatgggcgc aaagcttgat ttactttcct gctaatattg ctgcattatc
     1141 gattatcttt gcgacacaat tgacgaactt attacaatta tctaccgatt atcttttgtt
     1201 gattgcagtg atcaccgctg tttctgtgac agggttgaat ttgttaggga caaaagtcgg
     1261 tgcttctgta caatcagtga cgttgattgt taaattaata ccaattgctg tgattgtcat
     1321 atggggatta ttgaccccag gacaaggaac tgtccagtta tttccaatcg aagctggaaa
     1381 agatgttact tttgtcgaag gattgagcag tgcgttgtta gcaacgttgt ttgcttatga
     1441 cggctggtta ggtgtcggtg caatggcagg ggaaatgaaa cggccggaaa aagatttgcc
     1501 taaagcaatt attcttggtt tgagttttgt aacagtcgtt tatctattga tcaattttgt
     1561 ttttttgaaa actttgccga ttgatcatct tgccggtaat ttgaatgcag cttctgaagc
     1621 atcagacgtc atttttggag gaatcggtgg aaagctggtc actattggga tcttgatctc
     1681 ggtatacggt gcattgaacg gttatacact aactgggatc cgcgtgcctt atgcgatggc
     1741 tttagaagac gagctacctt tcagtaaaca gctgacaaag ctttcaaaga agtttacggt
     1801 tccttatgtt cctgcggttt tccagttagc agtagcttgt attatgatga gccttggttc
     1861 tttcgacttt ttaacagaca tgttgatttt tgtgatgtgg ctattcagtt tactgatttt
     1921 tatcggtgtc tttattttaa gaaaaaaagc gccggaattg ccacgtccat ataaagtacc
     1981 actttatcca atcgttccga ttattgcgat tctcggtgct attttcattt taggtatgac
     2041 gatgatgacg caaacgaaat tagcattgat cggtataggt gttaccttga taggtatccc
     2101 agtctattat caaaaaaaga aaaaacgctc agaagagtaa aatatttcaa caacagacag
     2161 aaaaagtacg aactaggtcc tctagatctt cgtgcttttt ctatttcaat aaaacaagtt
     2221 cttctatttt gatttttgct acttctgcaa gtagtgctta tgtgctaaag taagaatgaa
     2281 aaggagagat aaacatgata tttgattctc atacccattt aaatgctgaa cagttcaatg
     2341 aagatattcc agaaacgatt cagcgagcac aagaaatggg ggtaacgaaa atggcggtcg
     2401 tgggcttcga tacgccaacg attgaaaagt ctttgcaatt aagccatgac tatccaaata
     2461 tatacagtat tatcggctgg catccgacag aggctggcag ttatacgaaa gaaatcgaaa
     2521 ataaattaca agaacaattg actttaccaa aggttgtagc attaggggaa attggcttgg
     2581 attatcattg gatggaagac ccgaaagaag tccaagataa agtatttcgc agacagattg
     2641 ctatcgcaaa agaaatgaac ctaccaatca gtattcatac tagagaagca cttgaagaca
     2701 cgtatcaaat cctaaaagaa gaagatgttc gagatatcgg tggaatcatg catagtttca
     2761 gtggtgatta tgaatgggca aaacgatttc ttgacttagg gatgcatatt tcatttagcg
     2821 gtgtcgtcac tttcaaaaaa gcattagacg tccaagaggc tgcagcaaat gtaccaatcg
     2881 aacgattact tgtggaaaca gatgcccctt atctggcacc agttcctttt agaggaaagc
     2941 gaaatgaacc aggctatact cgttatacag tagaaaagat tgctgaactt cggaatcttc
     3001 cgacagaaga agtggctgcc caaacatgga caaatgcgca ccgattattt ggtctaagcg
     3061 aacatggata agatgaagat ccaagagatt atagtcgttg aaggaaaaga cgatacaaga
     3121 aggctgcggg aagtagttga tgcagatacg atagaaacaa tagggtctgc aatcaatgaa
     3181 gagatcctga tgcaaattga acatgcccaa gagactcgtg gagtgatcgt ttttaccgat
     3241 cctgattttt caggagaaaa aataagaaaa atcattatgg aagctgttcc tcaggcaaaa
     3301 catgcttttt tgccgcgcac acaagctaaa ccaaagaaaa agggaagcct tggtgtcgag
     3361 catgcaagtg atgctgctat tttagaagca ttgaaaaagg tcgtgacgcc agacatttcc
     3421 caaacggctg tttctgaaat cactagacaa gaccttttag actatggttt aatagctggg
     3481 gcacaagcaa aagaaaaacg agaaaaacta ggtgacgagt tgcgcatcgg ttacacgaac
     3541 ggcaaacaat tggaaaaacg tttgaagatg tttcgtatta cgccgaaaga actcgcccaa
     3601 gcaatgaaaa tagtggagga acaacatgag tgaatatcgt gaaattgcga caccctctag
     3661 aacaaaagag attttattga aacatggttt ttcatttaaa aaaagtttag gacaaaattt
     3721 tctgactgaa ccaaatattt taaggaaaat cgtagaaact gcgcaaatag atgaacatac
     3781 gaacgtgatc gaagttggac caggaatcgg tgcattgacg gaacaattag ccaagcatgc
     3841 aaaacaagtc gtagcatttg agatcgatga tcgtttgatc cctgtattgg ctgatacgat
     3901 gcaaccctat gacaatgtga ctattgtaca tcaagatatt ttaaagaccg atttgtcaac
     3961 agctgttaga gaaacatttc atgaggagct tccgttaaaa gtcgtagcga atttacctta
     4021 ctatattacg acaccgatca tgatgcattt tcttgaatca gatttggttg tggatgaact
     4081 agtcgtcatg atgcaaaaag aagtagctga tcgtatctct gctgaaccag gaacgaaagc
     4141 ttatggttca ttatcgattg ctgttcaata ttatatggaa gccagtttag cattcatcgt
     4201 accaaaaaca gtatttgtcc ctcagccaaa tgtagattca gcgattttga aactgacaag
     4261 aagagatata ccggcagtcg aagtgacaga cgaaaaagca tttttccgat tgacaaaagc
     4321 ggcatttcag caaagaagaa aaacgctttg gaataacttg cagcattcgt atggcaaaga
     4381 tgaccagaca aaagcatggt tagcaaaaag cttggaaaca gctggaatcg atccaaaacg
     4441 tcgtggggag actttgtcat tacaagaatt cgccgcatta agcaatgcga tgtcagaaaa
     4501 tatgcagtaa aaaaagaggt tgtgacagaa gttgtgaaaa agctgtcctg catcaagtaa
     4561 taagaacagc caaacaaaaa tagttcctca tgtttttcgt ttgtttgggc ttattaccgc
     4621 agatgcaagc ttttgaacac cgtttaagaa agaggttgtg ggcctgccgt ttaactctaa
     4681 gtcacaagga acaatttcaa aaaacagctt ctcatgtttt tgagttagtt ggtcttatta
     4741 cttgatgcaa gcttttgacc actattatgc cgaacaagga gatgtgacac aaattttgtc
     4801 acatctccta tttttgtttc ttgatcaaaa aattcttata cttgatactc acactcattt
     4861 tgtatggatt tagaaaagaa tatgtgtctt gacagttatt agtaagtgag ttatactaag
     4921 tcgacattta tgtgtcaaga catattagga gagagaaaaa atgagaaaaa attcagttcg
     4981 aaaactaacg atttctgctt tattgattgg gatgggggtc attatcccaa tggtcatgcc
     5041 taaaatcatg attccaccag cttcctttac tttggcgtct catgtgccat tatttattgc
     5101 gatgtttttt acaccaggag ttgcagtggc tgttgcgcta ggtacgacat ttggtttctt
     5161 tttaacaacg ccggttatca tcgcattgcg agcattgtca catcttgtgt ttgcgttgat
     5221 tggggcttgg tacttgcaaa agcatccgag tatcgtttta aaaaatggac agtttacttt
     5281 tgctaattgg cgtttccaag ggttcaattt tgtgatcggt gtgattcatt ctttagcaga
     5341 aatgctagta gtcagcatct tttactttat tggtaatatg cctgaaacat attattctca
     5401 aggatatttt tatacagtat tcatcttgat ggggattggt gggcttatcc acagtttagt
     5461 tgattataat attgcttatt ttatagcagg aacactcagc aaatattttg atatccccgt
     5521 atttacggca gcaaaaaaag aaaatcggaa agagtcgatt caagggtacg cgaagaaaac
     5581 gacatattag acatgatctc tcaaaaaaaa aactctcatc tagtaatgga taataaatcc
     5641 tctaagatga gagttttttg tcctaaaaag agctgcacca acatcttctg gcacagctct
     5701 aacagggggc aatttatgga agtttgatga cttgttctgt ttctttatca aagaagtggc
     5761 ctttgctgat gttgaaggca aggtcgacta tttcgcctgg tttatggaaa tctcttgcat
     5821 ctacttttga gatgaactca gtagaaccag tttttgtgta aagcatcgtt tcagctccaa
     5881 gtaattcgga aacgacaact tctgatttca ctacggcttc aggtgaagct tcaagggcta
     5941 cttgttcact gtggatgtct tctggacgaa taccgaagat aacttctttt ccttcataac
     6001 ctttttcaac taatactttg ttttttcctt caggaatacg aagcttaagc ccatgtccat
     6061 ctgtgataac accatttttc aatgtcacat taaagaagtt catggcagga gatccaataa
     6121 agccggcaac gaacatattg acgggtgtat cataaacttc tttcggtgta ccgatttgtt
     6181 ggataaatcc gtctttcatg ataacgattc ggtcagccat agtcattgct tctgtctgat
     6241 cgtgagtaac atagatggtc gttgtttcaa gacgctggtg aagtttggca atctcagcac
     6301 gcatggctac acgtaattta gcatctaaat ttgataatgg ctcatccatt aagaagactt
     6361 ttgcatcccg aacgattgcc cgtcccaatg ccacacgttg gcgttgtcca ccagataaag
     6421 cagctggttt tcgtttcaag tattctgtca gacctaagat ctctgctgca ttgtccacac
     6481 gttttttgat gtctgcttta tcatatttac gtaatttcaa gccaaaagcc atattatcaa
     6541 aaacagtcat atgaggatac aatgcgtagt tttggaaaac catggcaata tcacggtctt
     6601 taggtgccac gtcattcatg acttttccgc cgatatttag ttctccttca gagatatctt
     6661 ccagtcccgc gatcattcgc aaagtagttg actttccaca accggaagga ccaacaaaaa
     6721 cgataaattc acggtctttg attgatagat taaaatcagt tacagaataa ttttctgcat
     6781 tgtcatattt tttatatacg tttttcagag ccatttctac cataatacgt tccacacttt
     6841 cttttttagt tttattaact atttaaagta taaatgaaag cgttaactaa cttcaatgtc
     6901 atgttgaaca agaatttttt cttttttttg tcaatgtgct agttttaagc tttaataaat
     6961 atccataaga aataaaaact gatacactgg agtaaataag tatgttaaca atatcaaaag
     7021 gagtgtctct tatgaaaatc gctttgatcg ctcatgaccg aaaaaaacct atgatggtga
     7081 aattagcaac agcgtataaa acaatattgg aaaaacatga actttttgct accgggacga
     7141 ctgggcagag gatcacggaa gcaaccggct tgccgatcca tcggtttaaa tccggaccgt
     7201 taggcgggga tcagcaaatt ggagccatga tttcggagga tcagttagat ttggtgattt
     7261 ttcttcgaga cccgctggct gcacagcccc atgaaccaga tgtaacagca cttatccgtt
     7321 tatctgatgt ctatgagatt ccgttagcta cgaatatcgg aacagctgag gtgctactaa
     7381 gaggactgga agccggcttc ctagattttc gaagaatcgt ccatgaaata gacaagcatc
     7441 cactttcatt ttgatggata agcgtatgga aaaataacgt ttaatgttcg cctatatgta
     7501 gctataaaag ctaaacaaac tgataatatg cgatataata cgaacgtatt ggataatata
     7561 aacaataata ttagtttttc gtatttgcag taaatgtgaa aatatgctat agtttctgtg
     7621 ggaaaagatc ccaaaaataa tacagagtag aaaataaagc gttaagtgct aagaggatgg
     7681 gatgttgcct cttggacgaa ggacgtaatg ttcgcggttt tattttcgca ttcgctgcat
     7741 gatacgatgt agcagctctt aaaggagatg ctaaaaatga agaaacaccg gttagacgca
     7801 cgtatgattg ctattatggg cttattgatt gcattgatgg tcactttgtc ccgactggta
     7861 gcaatcgaga ccccatttat taaaatcagt gtcacattta ttccacaagt gatcatgggc
     7921 attctttttg gtcctttttg gtcagggata ggcgcagttt tagctgattt agtaggaatg
     7981 gccctcttct cgaaatctgc attctttatt ggatttacat tgaatgcatt tattgaagga
     8041 gcaatctacg gattcttttt ctatcgaaaa gagatcactt ggaaaaatgc cattctggct
     8101 acgcttagtg tcacgctgat catcaactta tttttgacac cattatggct tgcgttgatg
     8161 taccatgtgc cattgttcag ctgggtcgtt tgggcgcccc gcctgttaaa aacagtaata
     8221 tggttaccga ttcaatcaat tgccatttat tacgtaggac gtagtattcc ttacaaaaaa
     8281 attttaagaa gtttagcgat ccacgctaaa taaaaaacaa gcagtcttcc catcccagaa
     8341 gactgcttgt ttttattgtg ctgtgaattg tgcttgatag agccgtcggt aataaccatc
     8401 tttttgaagc agctcatcat gggtgcccat ttcgacaata gctccctgat ccatcactaa
     8461 tatctggtcc gcatttttga ttgtggacag gcgatgggca atcacaaaac tggtttttcc
     8521 ttccatcatt gctaagaagg cttgttggat ttttttctct gtcaatgtat cgactgagct
     8581 ggtagcttca tctaagatca acataggggg attactgatc atcgttcgag caatcgtcaa
     8641 cagttggcgt tgtccatctg atatctttaa cccttgaccg ccaatcttag tatctaattt
     8701 ttccggcaaa cgttctacaa attcatacat ataagaggct tttagggcat cattgatttc
     8761 tgcgtcactt gcttccggat tcccaaaacg aagattttct cgcaatgtac tgtcaaatag
     8821 ccaagtatct tgtaacacca ttccaaaact tttacgtaat gtatcacgtt ggatagagcg
     8881 gatgtcatgg tcatcgactg taattgttcc ttttgttgtg tcataaaaac gcatcagcaa
     8941 attaacaagt gtggattttc cggcccctgt ttttcctact atagcaatgg tttgacctgg
     9001 ataagcagta aaattgaaat cttcgatcaa acgctgcttg gggtcataag aaaaagaaac
     9061 atgatcaaaa gagacttttc ctttgatatt tttgggttcc aaggcatagg catctggcaa
     9121 atcaggcttt tcttctggct gatcgatcaa atcaaatgct cgttctagac cagaaaaagc
     9181 ggtttgcagt tgtgtcgtga ttccagaaag ttcgataaat ggtttagaaa actgacttga
     9241 gtagatcgta aagctggaaa tcacaccaac agtgattgac gaaccactct tcaatgccaa
     9301 taggccgcca actaaaccaa tcgataaata agcaaggtga tctacaaaac gagaagacgg
     9361 gtttgtcaag gaagaagaaa attgtgcccg ttgtcctttt tcatatagat cagcatttag
     9421 cagttcaaat tgctgttgac tagcttcttc ttgctgaaaa gctttcacga ttttctggtt
     9481 accgattcgt tcggtcacaa agcccgagat atccccaata atcctttgct gtctatcgaa
     9541 atttgtttgt gaagcacgag caacgatcca actcacaagg aaaataattg gtgtagaaca
     9601 aagaacgacc aatgtcagaa gtggacttag acgcatcata aaaataaacg aaagaatgat
     9661 gattgccact ccagaaaata attgattgaa ggccgcagaa attgcaatgg aaatattgtc
     9721 catatcattt gtaaatcgac tgacgatatt tccgtgggag ttttgatcat aataacgaag
     9781 tggcaatcga ttcagatgag caaatgcatc ttttcttaat tttgcaacgg ataagtaagc
     9841 taaccgattg cttaacactt ggatgagcca ttgactgact acgttgatta aaacgatacc
     9901 accgaataga ataagtaaat ggaacagtcg attgaagcgg acctgtcctt ctccaatcat
     9961 ttgatcgata ctttgaccaa tttgtaacgt catcacaact gttgcaatcc cattgatgat
    10021 tcctagtatc acagctagcc aaatgtcttt tgcataggca gtaaggtaag gaatgaatcg
    10081 gcggagcgtc tgcaaggata atttttttac tttcataact attcttcctc ctgtgatgcg
    10141 acgatttcct gatattctgc tgattgagca agtaattctt catgggtacc ctgagcagca
    10201 atcttacctt gatccatcac taagatatga tgtgcttctt gaatagagcg gacacgttgg
    10261 gagataataa tcactgtact gccaagataa gtctgtagcg ccttacgcaa atccaagtct
    10321 gtttgataat ccaacgcact taaagagtca tctaaaatca gtaatgctgg cttggcaatc
    10381 aaagctcttg caatcgtcag tcgctgtttt tgtccgccag agaaattttt cccattttcc
    10441 atgacttttg tatctaaacc atttggaagc tgacggacaa attcttctgc ctgagcgatt
    10501 ttcagagctt cccaacattc tttttctgtg gcgtctttct taccccattg aaggttttca
    10561 cgaatagtcc cggtaaatag tacagaagtt tggggaacaa gagcaatttg ctgacggaga
    10621 tgatccagct gccaagaacg aacatccatt ccgtccatta taactgtacc ggaactgaca
    10681 tcatagaaac gcggaatcaa ttgtgtcaaa gtcgttttcc cgcttccggt tggaccaatg
    10741 attccaagga ctgtatttcg cttcagctga aatgtaatat tttggagaga aagaccagaa
    10801 tcaggagtat aacggaagtc aacatggtca aaagcgataa ttgcttcaga agaaaaatcg
    10861 ggagtagtac tgacctcagc ttcaagaatc gaattttctg tgtctagcac ctctttcacc
    10921 cgatttcctg aagcttcggc acgtgtgaag atcacgacga ggtttgaaac aacgatcagt
    10981 gccaaaagca tttgattcat ataattgatc aaagcaagaa cttgtccttg ttgcaagcta
    11041 ccaatattta ctttgatccc gccaactgtc agcaaacaga tgatcccgac attcatgatc
    11101 aaggttgtag caggtgataa tagggcagag atattggaaa cacgtaaata attgttcgct
    11161 agatcatttg tgcttttatc gaacttctct gtttcttttt ttgtctgcgc aaatgcgcgg
    11221 atgacacgaa caccgctaag attctgacta acgtgttcat tgagctgatc tagtttttct
    11281 tgcacttttt ggtagagagg aacggttttt ttgatgataa aaaataaaat gattgagaaa
    11341 ataggcaata atgctaagaa aaacagacct acttcccagt cgatcacaaa agccatgacc
    11401 actgacccga tacttaaaaa cggtgctctg atcaataaac gaatgaccat tgctaaagct
    11461 agctgaagct gattgatgtc gtttgtcatt cgggtgatca aggtatctgt tccaaaatga
    11521 ttcaactcgt tgtgagagaa agtattgatt tttttgatta gctgattacg taactctgta
    11581 ccaaatcctt gtgaagctac tgaagcatag tattggcaaa tgatagcaca aatcagacca
    11641 atcacagaca tagcgaccat ccataagccc atttcaatga tttttcctcg gtcattcatt
    11701 tttagtccat tatcgatcaa ggaagccatc attaaaggca ggacaagttc gaagacagct
    11761 tcaagaaatt tgaagaacgg gcccaaaatg atttgcttac gatagtcttt tgcataacgt
    11821 aataactgaa tcatatgatt cctcctatta tttatttgtc cacaattgaa aaaacaagta
    11881 ctaccacatt gtagcttagg aaatttagaa tgaaaagaga acaagccttt tcataaatga
    11941 aagttttatt atgaagaagc tttagaaatt gaatagacta ttttttttaa aaaaaagaaa
    12001 atgagaaaac atgccagtct cttcattcat aggaacgtct attttactta atttttctat
    12061 aaatgaattc tgcataaaaa atatatcaag taaatgttta tagatgaaac tctatttact
    12121 tcttttttaa tttgttcttg caatcttttt tgctacgtaa tttttgtaaa aaagtgggtt
    12181 gagagaaatc taattgattt tcaaagaagg agtatgaaaa tgagaaaaat atttattcgt
    12241 ttattgtggg tactatctta gaggaataaa taatagtgga gaaaactatg gtttggcgca
    12301 gattctatca ggtttgatgg aacgaagaca acctcccgac atcaagtcaa aagctacttg
    12361 agattttgat ctgaaaataa aaaaagaaaa caaggtagga acatcaatgt ttctaccttg
    12421 ttttcgtaat caatgggaaa aaactaagag tggtgtacgt aatcaataaa aaggatggtg
    12481 acaacagtac ctctttactc tctgaaagca tcataactcg tttttcctca ttatgccaat
    12541 aaattgttgt tataccacat ataaggattt gtaatagcta aaaacagaca ggaaagttga
    12601 aatctgtgaa tcttattttg tatggaagga tttatagaac gcaaaaatca agataaagat
    12661 gaataaaaat cctgtttcgg ctatatattg cgtatctacg ccaataaaac gagtttgttc
    12721 tgtcatagcc atataaagca aaggcaaaaa tacaactaca gcgagataag atccgatgat
    12781 ttctcgaaaa gttttccagg aagtatgttt cctgttttta tatttatccg atttcattga
    12841 atagtcatag cctccttatt ctttcatatg ttgaaattcc agtataaaaa ctggaaggaa
    12901 ctgtacgttt tttagaataa aaattataag ggataagtag gctgctgtct ataataagat
    12961 atatttttca attctttatt aaagatttta ttgacaaaat gaatccgttt tctatgatgg
    13021 aggaggggtg aataagttgt tgaagaagga aattttatgt tacttagaga accagacagc
    13081 ctttttcgat ttagaacata tgaacgaggt ctttacagca caaaggttag ctgatcattt
    13141 tggggtaaaa agaaacacag tcagtcatta tttgaaccag ttaaatgatg agcaactact
    13201 agtcaaaatc aattctcgac cagtgattta tttccacaaa gaagcttttg aaaaacaatt
    13261 ttttaagtta cgcacgaatt tttatttttc tatcgatgat ctcaaagagg aacagccttt
    13321 tttcgcgcaa ccaaaagact tattctcttt tatgatcgga tacgacgcca gtttgaaaga
    13381 aagtatcgaa caaatcaaaa cagctcttta ctatccagat ggcggattac cacttttgat
    13441 tacaggcgaa agtggcacag gtaaaagtta tttagttaat ttggtctatc agtattgtct
    13501 gcttcatgat ctgctagaag attctgcacc attcatcact tttaattgtg cacaatatgc
    13561 agataatcct gaacttttga ctagcaattt gtttggacat gttaagggag cgtacactgg
    13621 tgcagaagaa aataaaaaag gggcttttga agcagcagat ggtgggatct tgtttttaga
    13681 cgaggtacat cgcttaacac cagaaggtca ggaaaaactg ttcacctatc ttgatcaagg
    13741 tgtgatttat cgtatgggag aacctaattt gtcacgccgg atcaaaacac gtctcttttt
    13801 tgctacgact gaagagatta ctagtcattt cttaacaact ttcattcgaa gaatacctat
    13861 ccgaatcgaa ctacctgcac ttaatcagcg tagtcgtaat gaacggctag aactgattta
    13921 ctcttttttt ctcgaagaac aaagaaaaat ggggagccct ttgtcagtca gtggaccagc
    13981 tttgtcactt ttaacaagtc agaaattatc cggaaacata ggagagctga aaaatatcgt
    14041 caaagtttca gcagcaaaag catatgctga acagcgtgaa cagcctgaaa tccatgtcac
    14101 gatccatcat ttgcaaaaag aactacttgc gcagcctatt actaaaaata cagcacagca
    14161 aggaatctat attacgcaag accagacctt agagcaatta atggagaagc aacagcccga
    14221 acagcagcga atcgttaaaa gttttgagca aatcctaatt gatttcaaga aaaataactg
    14281 tctgctatat tcttgcgaag gaaaattaaa gcaagaagtg attcaattat ttgatttttt
    14341 gctgtttgag accagtagac aagaaaaaca cgagctgctg gtttattgga cacaatctat
    14401 ccgagagacc tttcgacaaa tggaaactgc ctatcaaatc aaattcgatg gaaacagtgt
    14461 ctatgccttg agttactatc tctatcagcg aagcactatc aaatggttac cggaagaaca
    14521 tgatattatc caactaatca aagaattaga acaacaagtt tctcagtctt atccatctag
    14581 ttatcactat gtccaacgaa ttctggaatt aagtaagatc aaattagata ttgaagacac
    14641 aagtatggat cggattttac tgacgatcta tctaaaaaaa gcgaaatggt caaaagaaaa
    14701 acgactgcca aaagcgatga ttgctgctca cggttatgca actgctagca gtatggcaaa
    14761 tgtagtaaat cgtttattac aagaggatct atttgaatca tttgatatgc cactagatgt
    14821 cacaccacag cagattgctt cagaaatcct tgattattgc gaaaacagcg atgtttcaaa
    14881 tggattgatc atattagtag acatgggatc tctgaaagaa atccatcagt tttttaaaaa
    14941 acagttatcc gtaccgcttt tgattttgaa taatgtgacg acacctttag caatcacagt
    15001 aggggaatgc ctgcaaaaaa atgtatcatt agaagagata gcagaagaga ctgttcgaca
    15061 gatccagcca gaatggcgac tgctctatcc agaggaaaac aaacccaaag cactcattac
    15121 tacttgcttc actggaatcg gtacggcggt ccacttaagt gaactgctag aaaaaagctt
    15181 acctacggct tgtcagttga aaatcatccc atatgaatat cagcaattaa aagataagaa
    15241 aaacagtgac ccattatttt ccatatacga agtcgtagga atgattggca ccacagatcc
    15301 tgatatcacc aatatcgact atctttcatt agaagacctc atctcggggg aaaagatgtc
    15361 tgtactagct gaatggttgg acactactat gaatgcttca gagaaggaaa tattcaatca
    15421 gcgcatcatt cgtaattttt cattggaaaa agtactggat tccgtgacta ttctagatac
    15481 agagaaggtg atgggagaaa tcgatcattt tatgagagaa ttagaggtgc agttgaatcg
    15541 aagcatcagc aatcccaaaa aattagcgtt gtatgtccat gtgagctgtc tcattgaacg
    15601 attgatccga caaatgccaa tcgaaaccta tcaaggatta gagaaatgga agcagtgtca
    15661 aaaagaaggg ttatctgcta ttaaatctgc gtttagtgtc attgaagagc attatagtgt
    15721 catgatcccc aattctgaga ttgcctatat ctatgatatt ttgagtgaag atacagagtt
    15781 tctctcgata gaagaagaat tttgaacata agcaagttgt tgccactaat tttggcatgc
    15841 aacttgcttt tttagtatgt gtaagtgaaa agaggagatg aaaaagtgga tagagaaatt
    15901 atcttagctt cccatggaaa atttgcttca gggatattag attcattaga gctgatctat
    15961 gggaaaaatc attctattac tgtattcgat tgctatactg atgagaattt tgatttagcg
    16021 gaaacagtaa ggcagctttt tatgaggtac aaagataaag aaatcattgt tctgacggat
    16081 ctttttggcg gaagtgtcaa caacgaattc ttacaatata tcaatcggga tcatgtctat
    16141 ctcgttgccg gattgaattt gccactattg attgagctag tatctcggtt ggacgctgaa
    16201 gtagagacaa ctgttttgat ccagcaggtg ctaactgatt caaaaaaaat gatccagttt
    16261 tgtaacgagc ggctcaatca gaaaatagaa gaagacgaat tttaggagga agaaaaatga
    16321 ttgtattgac aagagtcgac catcggttat tacacggaca agtagctttt tcatggacac
    16381 aaacaatagg cgcagactgt attttgattg ctaatgatga tgtacctacg aatgagatac
    16441 gaaagacaac gatcaaatta gccaagccac aaggagtcaa actagtgatc aaatcaattg
    16501 atgactcgat tgccgcgttg aaaagcgggg tgacagataa atataagtta ttcatcgtag
    16561 tggaatcgat cgaggatgca tataagctgg cagaagcgta tccagaaatc aaaaccatca
    16621 acttaggagg gatcaaggca aaacctggta ctcgcagcat cggaaaagcg gtaaatattt
    16681 taccagaaga ggaggaacgc ttgaaacgat taattgacaa acaaatagaa gtagaaatcc
    16741 gtcaagtacc agcagataaa aaagtggatg taagagaagt tttgtaagaa aggaagaacc
    16801 tcaatgattg tacaagcagt cttattagga attgttgcat ttgtcgcaca atcagaatat
    16861 gcactaggga catcgttgct ttctcgtccg attgtgacgg ggctgtttac aggaatcgtg
    16921 ttaggtgatg taaaaactgg gatcattatg ggcgcaactt tagagttagc atttatcgga
    16981 tcgttctcag taggtgcttc gattccacct gatgttgtga ccggtgggat tttagggacg
    17041 gcttttgcta ttacagctgg agccggtaca gaaaccgcgc ttttactagg tttgccgatt
    17101 gctacgttga cattgatatt gaaaaatatt tacttagggc ttttgattcc aattatgaac
    17161 cataaagcag acaattatgc agaagaagga aattataaag gagtcgagca tatgcacttg
    17221 cttgccggta tcggtctttc cttgatgctt ggtgttgtgg taatggtttc ttatatggtg
    17281 ggaagcaata cgatcggaaa tctattaaat atgattcctg acttcgttca aaaggggttg
    17341 tcagtagcta cagggttgat tccagctctt ggttttgcga tgcttgctcg tttgctgatc
    17401 aacaaacaag ttgcaccata ttttttctta ggttttgcta tagcttctta cttagagatt
    17461 cctgtgaccg gagtagctat ttttggtgcg attttagcag ttgtggtagt caatattatg
    17521 aatgtccgtc aactaccact tcaaacaact gcaggggagg tagaagaaga tgaagaattc
    17581 tgagatcaaa aacagcaaaa taacgaaaaa agagctaaat cacgtatttt ggcgttcttt
    17641 tcaaatggag ttttcttgga attatgaacg tcagatgaat atggcttatg tttatgcaat
    17701 gattccgatt ttgaaaaagt tatatcagtc gaaagaagaa atggcagcag ctttgaaacg
    17761 gcatctagag ttttttaaca cgaccccaca tatcgttaca ctgattttag gaatcacggc
    17821 tgcaatggag gaagaaaata aggatgatcc tgaatttgat gtgactgcga tcgatagtat
    17881 caaaacatct ttgatgggac ctcttgcagg gttaggagat tctttctttt ggggaacttt
    17941 gcgattgatt gccacaggtg tgggtacctc tttagccatg caaggaaata ttttaggccc
    18001 tatcttgttc attttgattt tcaatattcc gcacattctg tttcgctatc tagcaacagg
    18061 ttggggatat cgcttaggaa cgggtttttt gaaaaagatc caggcaaacg gtatgatgga
    18121 aagtttgaca ttaggcgcgt ctattattgg actgatggtc gttggagcaa tgactgccac
    18181 gatgatcacc atcaatattc ctttaaaaat cggttcagga gaaaatgctg tgactgttca
    18241 aagtattttt gatgatatcg ttccaaatat cttatgtctt ggagcatttg gcatagtgtt
    18301 ttatctattg aagaaagaag tgaaaccatt aacgatcttg atcggactag ctttctttgg
    18361 aatttttggt tcgtggatag ggatttttta aaaaaggagc agagaaaatg tttacgatgc
    18421 aagattatat ctatgaagaa aaggaagtac taagtacgat cttgaaaaag aatgattttt
    18481 cgacaagaga acatatgaaa aaaacagtga atttactgat cttagcaacg ggttcatctt
    18541 ataacgcttg tttagcagcg aagccagcat tggaatctta tggtgatctt actgtcgata
    18601 ttcaagaacc tttttatttt ttcaattatg gaaaactttc tccttcaatc gatactgtga
    18661 ttgctgtgtc acaaagcggg aaaagtgctt ctactgttga agcagtaaaa atgatacaaa
    18721 aacaagggtt acctgttgtt gctatcacaa atgacgtgca aagtccactt gctttagaag
    18781 ctgcacaaat tattgattta ggtgccgggg tagaatcagt aggcttcgtt acaaaaggct
    18841 attctgcgac tgttttacag ttactactct tagggatagg aattggaata agtaaaaata
    18901 aaatcagcaa aaaaatagaa caagactaca tgcaacagtt gcgcaaaata atcaaccatt
    18961 taccagcgat tattcaaaaa acggaagaat tttttgatgg atatcaaagt ttatttcgtt
    19021 tagcacagcg tttcgtcacc attggatatg gtccaaactg gggaacagct aaagaagcag
    19081 agacgaaatt gactgaaaca atccgcgttc cgtcacaagg atttgagtta gaagcttata
    19141 tgcacggccc atacctggag gcagatgctt cgcatttgct attctttatt gaaggggaaa
    19201 gtgtaaataa ggaacgttcg caaaagttgc aaagatatat gagtcggtac gttggagaga
    19261 ctctcaccat taccacaaaa aaagcaagaa acgagaaaac acttggatta gcaatagaat
    19321 gtgatgaata tctgtctgta ttagcgcttg tcgttccgtt tcaactattc gcttataaaa
    19381 ccgcagtagc taaaggtatt gacttgaaca aaaagatttt tgaagacttt gatacagtct
    19441 tgaaaagtaa attataagag gtggaaatca tgctgaaatt caatgaagaa gaacaaatca
    19501 aagcaataaa aggcgcacta gctttacgtc cgcaagtaga agaaatcatc gataaacttt
    19561 atgcggaaaa atttgacgct gtctattatc taggaatcgg tggaacgtat gcttcctcga
    19621 tgcaagctgt cacttatatg aatgggaaaa gcaacttgcc tgtctttgta cagcatgctg
    19681 cagaatatta cactactgga aacaaaagat taacaaaaga ttctatcgtt attttgtcct
    19741 ctgttaccgg tacaactcaa gaagtagtga aagcagtaga acaaatcaag aaagtaggag
    19801 cgacactgat tggatttatc gataaagcga acagtaagtt gtctcagcta tgcgattttg
    19861 tggtcactta tccagctcct ggaacagaac aaatcaaatt ttttatggca gcagatcgat
    19921 tgatgtattt gaatggagaa ttcgaagctt attcagaata ctatgaacag ctcgaacgtt
    19981 atttaccaac agggttagtg gaagcagaga aaaaagcaga tgcatttggc ttatcatttg
    20041 cagaaaaaca tcgacgtgat agtatgcatt attttattgg agcagggaat caatggggag
    20101 ctgtttattc atatgccatg tgttactggg aagaacaaag ctggcttcca tcgaaatcta
    20161 tccatgctgc cgagtttctt cacgggacgt tagagatcgt agaagaaaca accccagtca
    20221 cattattttt aggcgaagat gaacagagag tgttatctga acgtgtggct aaacttttgc
    20281 caaaaatttg cagcaattat acattgatag acacaaaaga ctatccagta gaaggtatca
    20341 gtgaaaaata tcgcggacgt gttttgtctt tcttattgat gcatgtagtg acacaacgca
    20401 tcgatgctca tgtggagcag ttgaactgcc atccattaga gatacgccgc tactatcgtc
    20461 agtttgatta ttaggataga ctggataaaa agaatataaa aaataaagag agcagcgata
    20521 actgctccct ttattttttt aaaatattgg catcaattac gttataaaac acattttttg
    20581 cattatctac agttcaactt ataatctgtt taatgggaca tgtgggtgcc aaccattttt
    20641 tgttatgcaa tagtactatt tagttgttgc atggatccgt agtaaaagtc caagtacaac
    20701 gagttgcgcc agtttacata gcgttttgta tccagaatgt tgactaaaac aaaagttcct
    20761 atgtcaaccg tcaacagaga caatctgtcc gttgcaggac ctgacagatt tagaaatgtt
    20821 caatctgtct cttatgtatt ttaaatcaat actcactagg agaagtttcc taacctccta
    20881 atagtaatgc tggtagtaac attgtcaaaa ctgcttcctc ttaggaacaa gcaaagcata
    20941 acgagtgtaa aaataaaatg tagactattg taacatatca ttgattattt caagtaaaaa
    21001 cgataaaaga agtaaacaaa cacttaaaaa caatggaaat tagtcccaac tttaagaaat
    21061 gtatactata atggaaatta tcaattattt atttggagga atatccatga aacaaaaaat
    21121 cgcagttctt ggtcctggat cttggggcac tgctttagca caaacattgg cagaaaacgg
    21181 gcatgatgtc cgtatttggg gaaatgtacc tgaacagatt gatgaaatca ataagtatca
    21241 tacaaatcag cattttttac ctgatttgac gatcccagaa tcgattatcg gatataaaga
    21301 attggcagaa gcagtggata acgcagatgc tattttattt gttgttccaa caaaagcgat
    21361 tcgttcagtc gcacaggaac ttattggtaa aatgaatact aagccaatca ttatacatgc
    21421 aagtaaagga ctagaacaag atacgcataa acgaatctca gaagttttgg ctgaagaaat
    21481 tccagaagaa aaaagacagg caattgttgt attatctggt cctagccatg ctgaggaagt
    21541 ggcagtacat gatatcacaa caattacagc tgcaagtatt gatcaaaaag cagcagccta
    21601 tgtacaaaaa ctgttcatga atgattattt caggatttat acaaataatg atgtgattgg
    21661 cgtagaaact ggtgcagcac tgaaaaatat cattgcaatt ggtgccggcg ctatccatgg
    21721 attaggattc ggagatgatg caaaagcagc aatcatgact cgaggattgg cagaaatcag
    21781 ccgtcttggt gtcgcgatgg gtgccaatcc tctgacattt atcggtttga gtggtgtggg
    21841 ggacttgatc gttacttgta caagtgttca ttctcgcaat tggcgtgccg gtaacttgtt
    21901 aggacaggga cataagctgg aagaagttct agaaaacatg ggaatggtcg ttgagggtgt
    21961 ggcaacgaca aaagcagcag tagagctagc tcaacagcta ggtgttgaga tgccaattac
    22021 tcaaacaatc tataatgttt tgtataatgg agaagatatc aaaaaagcag caaaagaaat
    22081 catgttacgt gacggaaaaa tggagaatga attttctctt cgttaaatag atgatcaata
    22141 gttaatcgtc gtttaggagg aacagcaagt gaaggtcaaa aaagcagtca ttcctgccgc
    22201 tgggctagga acacgttttt tgccggcaac aaaagccatg gcaaaagaaa tgcttccaat
    22261 cgtggataaa ccaacgatcc agtttattgt ggaagaagca ttggattcgg gaatcgaaga
    22321 catcttgatc gtaacgggaa aagaaaaaag acccattgaa gatcactttg atgcaaatat
    22381 cgaattggaa aacaatttgc gggaaaagga aaaaacagaa ttactcgctt tagttgaaga
    22441 aacgactcaa gtcaatcttc acttcatccg tcaatctcat ccaagaggac tgggggatgc
    22501 cgtgcttcaa gcaaaagcat ttataggaaa tgaaccgttt gtcgtcatgc tgggggatga
    22561 tttgatgaaa gatgatatcc cattgactca acaattgatg atggattatg aagaaacaca
    22621 agcttccgct gttgccgtca tgcgtgtacc agaaaatgaa acatctaaat acggaattat
    22681 tgatcctaaa acagatagcg aaaagggtcg ttgcagagta aaagggtttg tagaaaaacc
    22741 tgaaatggga aaagcaccaa gtaatttagc cattatcgga cgttatctac tgactcctaa
    22801 aatatttgag atattagaaa ctcaagaacc aggagcagga aacgagatac agctaacgga
    22861 tgcacttcag actcttaacc agacagaggc ggtctatgcg agagagttta aaggaaaaag
    22921 atacgacgta ggcgataagt taggatatat gaagacaaat attgaatatg gacttcaaca
    22981 ttcggaaatt gggacttcat taagtgcata tattatccag ttgagtaaaa agctaagaac
    23041 agaaagttaa ctggaaataa gtggcctgct gagaatgaaa ggctatttgt tattaaagcg
    23101 gcagcttgtg cgtcatttgc gcaactgtcg ttttagtttt ttgactctag atcagttgag
    23161 tcgtggaaaa cgaaagatag aaaaagactt tcgtgaatag attcagaaaa tattatgcta
    23221 atggtttaat ttttttttaa gttgtataaa agaaaatgat tacataagag aaatgaaagc
    23281 caagccagaa gattcatagt agaataaaaa ggcgaatttt ttaattataa aaaaaggtgt
    23341 gtgttcacta tgggaaaatt agtcgctgtt gcacagtcgc tgcttgatat actcaagtgg
    23401 ctgatggaag gaagcaattg gatatttgtg ttgccactat tgcttattag tctatttatc
    23461 atgtttcgca tggtcagaaa aaaagaaacg tttctgattt ttatctggta tgcagcatcc
    23521 gttggggttg ctaccttgat ggttgaattg gcgttaggta gttgggaagc ttgcgtattt
    23581 gctttatttt ttgctgtact gtatctaatc atttatatcc catatatgaa aagaaagtct
    23641 cggataggca gaaaaggtag acatacaact actttttcta gtacagattc tctcgaacaa
    23701 agtagaagaa cgagaagaag acggtaatat ttagtaggta tacgcaaaaa aagataaaat
    23761 aatggataaa ctattgagat gagagattta tttaattggt ggaaaaaagc ttttttcact
    23821 tatataaaag aatctttttt aaaggaatgc ttgttgtatc gggataagcc attccttttt
    23881 ttatgttatt tatatatata taaatcatac caatgttttt ttgtattttc ttgcttgcac
    23941 ttggataaga gattacttac aataaattca gatagaaaca gctgaataaa aaaaggctcc
    24001 ctgaccctta gttggcgcta agaatcaggg aatgaccagt cacacacata caccctgacc
    24061 gatcattttg ccatagtcaa tgcagtgcat cgacctaatt tattgtacct aatctagggt
    24121 gaaaattcta cccctatgta gatattttcc atggtctgca cgttgtttta tttgctatgt
    24181 caaggtattg ggcgtattcg ttcaatgcct tttttgtgtt tgaaacagca aagaccacat
    24241 gtgttactgt ctaactactg tttttttatg tacttcctta gattaggcag ctgtttctat
    24301 tcatgtcaag tatagctagg cgggagagat aaatgagttt atgttatttt gactattatc
    24361 accaattgga agagaaatta aggatagaag agccgctgat gcttcaagct ggcacttgga
    24421 tcgcgaaaca aattaatcaa ggtggtagat tgcagatata tgctagccgc acactaagtg
    24481 gtgtagcatt tgaattttgg gatcaaaccc cggatcttgt accaagtata ttgattgaaa
    24541 atccagccgg aggtgtctat gaaacgctag aaggtgcagg acaggcaatt attgatcagc
    24601 tttctgtcaa atcagaagac atttttcttc ttctttcgaa tgaaggaaga aacccggcaa
    24661 tcatcgaact agctcagtgg atcaaagaaa atggtcatcc attaatcatt gttactggat
    24721 ttgatttgtc acgaagtatc aaatcgcaac atagcagtgg tttgcgatta tttgaatttg
    24781 ctgatttggt tttggacaac cacgccaatt tacatgatgc agtcttgact ttgccaaatc
    24841 tagatccagc gatctgcgga acagcctctc ttgcaacgat ctttttgctg cagcaagttt
    24901 tgtattttac agcaaaacag ctagtccagg acacaagtgg aaaatagtta tccacatgtt
    24961 gacaaagttc cttaaaaaaa taatgttcca cataaaaatg gagcgtttga aaaaaagaaa
    25021 acgattatta atgaggatta acaacgacta ctttttttgt tttagttatt ttaagatgga
    25081 tcatctttga ttttaagctt gttttgttta aagtttgtta tttttataag ttgtttcaca
    25141 gttatgagaa atgagttata agaatatgta gtgtcagaaa aataaaaagt agtggaaaaa
    25201 gagacaagaa agaatccat
//
LOCUS       DACDLM010000039        24288 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.039, whole genome shotgun sequence.
ACCESSION   DACDLM010000039 DACDLM010000000
VERSION     DACDLM010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24288
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.039"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            123..329
                     /locus_tag="IV356_001654"
     CDS             123..329
                     /locus_tag="IV356_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAP9015343.1"
                     /translation="MNNRTFDILKWIAIVVIPALATFVGLVGKGVNWRYTDITVMIIT
                     GFGAFLGSILGVSNRTYKKISSDK"
     gene            340..1359
                     /locus_tag="IV356_001655"
     CDS             340..1359
                     /locus_tag="IV356_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP9015344.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RSDVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
     gene            1548..1621
                     /locus_tag="IV356_001656"
     tRNA            1548..1621
                     /locus_tag="IV356_001656"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1582..1584,aa:Ile,seq:cat)
     gene            complement(2134..2436)
                     /locus_tag="IV356_001657"
     CDS             complement(2134..2436)
                     /locus_tag="IV356_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015345.1"
                     /translation="MLMEGKTQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKDVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(2685..2885)
                     /locus_tag="IV356_001658"
     CDS             complement(2685..2885)
                     /locus_tag="IV356_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP9015346.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
     gene            complement(3190..4422)
                     /locus_tag="IV356_001659"
     CDS             complement(3190..4422)
                     /locus_tag="IV356_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAP9015347.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            4676..5245
                     /locus_tag="IV356_001660"
     CDS             4676..5245
                     /locus_tag="IV356_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP9015348.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(5423..5863)
                     /locus_tag="IV356_001661"
     CDS             complement(5423..5863)
                     /locus_tag="IV356_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HAP9015349.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            6021..6785
                     /gene="map"
                     /locus_tag="IV356_001662"
     CDS             6021..6785
                     /gene="map"
                     /locus_tag="IV356_001662"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HAP9015350.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            6817..7740
                     /locus_tag="IV356_001663"
     CDS             6817..7740
                     /locus_tag="IV356_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HAP9015351.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            7816..8955
                     /locus_tag="IV356_001664"
     CDS             7816..8955
                     /locus_tag="IV356_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HAP9015352.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            8948..9748
                     /locus_tag="IV356_001665"
     CDS             8948..9748
                     /locus_tag="IV356_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP9015353.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            9748..10575
                     /locus_tag="IV356_001666"
     CDS             9748..10575
                     /locus_tag="IV356_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP9015354.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            10553..11287
                     /locus_tag="IV356_001667"
     CDS             10553..11287
                     /locus_tag="IV356_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP9015355.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            11387..12253
                     /gene="rfbA"
                     /locus_tag="IV356_001668"
     CDS             11387..12253
                     /gene="rfbA"
                     /locus_tag="IV356_001668"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HAP9015356.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            12267..12839
                     /gene="rfbC"
                     /locus_tag="IV356_001669"
     CDS             12267..12839
                     /gene="rfbC"
                     /locus_tag="IV356_001669"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HAP9015357.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            12861..13889
                     /gene="rfbB"
                     /locus_tag="IV356_001670"
     CDS             12861..13889
                     /gene="rfbB"
                     /locus_tag="IV356_001670"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HAP9015358.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTSILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWQPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            13987..14838
                     /gene="rfbD"
                     /locus_tag="IV356_001671"
     CDS             13987..14838
                     /gene="rfbD"
                     /locus_tag="IV356_001671"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HAP9015359.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLPYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEALGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            14873..16906
                     /locus_tag="IV356_001672"
     CDS             14873..16906
                     /locus_tag="IV356_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015360.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFSLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMIAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFVALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            16950..18230
                     /locus_tag="IV356_001673"
     CDS             16950..18230
                     /locus_tag="IV356_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HAP9015361.1"
                     /translation="MKIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGVGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGGIAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVTEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            18440..19246
                     /locus_tag="IV356_001674"
     CDS             18440..19246
                     /locus_tag="IV356_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9015362.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            19258..20478
                     /locus_tag="IV356_001675"
     CDS             19258..20478
                     /locus_tag="IV356_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9015363.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGKVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            20468..22054
                     /locus_tag="IV356_001676"
     CDS             20468..22054
                     /locus_tag="IV356_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP9015364.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLYINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAQPQNSNYVKVLEVIQQTKQDEIIQQIPFNNFTGENETLSFHVSELA
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKDLPEFFLTDIAG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHYLIENNTRLD
                     QTLKTTINRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSLCIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVLREEVNQAKQLAEGAKAGFELRILCEK
                     ERSFLVEAVAQNGQSWIIEM"
     gene            22093..24231
                     /locus_tag="IV356_001677"
     CDS             22093..24231
                     /locus_tag="IV356_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP9015365.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEVQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRQENGHISLATNSALKMAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDLIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPAEHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVHPGRISGFYEITYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYPNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTAMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     ILEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPSYIAHDPFYNDNLTKEGIGDFSLRPD"
BASE COUNT         7708 a         4108 c         5010 g         7462 t
ORIGIN      
        1 agataaaatt gaacaactgg acgggcaaat tgatgccttg ctttcagaaa gagaaatatt
       61 gatagaagaa aacaagcgat tgaaaaagaa agtagcccaa ccaatgaagg gaggtggata
      121 gtatgaacaa tagaaccttt gatattttga aatggatcgc tatagtagtt atccccgctt
      181 tagcgacttt tgtcggtctt gtcggaaaag gtgttaactg gcggtacaca gatataacgg
      241 tgatgattat tacaggtttt ggagcatttc tagggagtat tttaggtgta tcaaatcgaa
      301 cgtataagaa aatttcatca gataaatagg aggatagata tgaaaaagaa aattactatt
      361 actgcgatga gcctgttaac ggctcttttt ttattgccaa ttaacggatt tgcctatact
      421 atcaacaatg aatttaattt gggcgcaaat gaaggtagct cacaagtagc aaataatcag
      481 tatattttac tgcatgaaac ggctaatgaa acagcaacag gacgcaatga agcgcagtat
      541 atgcaacgtt catggactag cgcttatact gcttatattg tgggagacgg cggaattgtt
      601 tatcaagtcg gtcaacctgg ttatgtacag tacggtgctg gttcgtatgc taatgccaac
      661 agtcctgtgc agattgagtt acaacacaca catgataaag caacgtttga gaaaaactac
      721 aaggcatacg ttgaattggc tagagattca gcaatgaaat atggtattcc attaacgttg
      781 gacactcctt ataaccaacc gggaatcaaa tcgcatttat gggtaacaca aaacatctgg
      841 ggcgatcata cagatcctta cggttatctt tctgaaatgg gcgtaagtaa agaaaaatta
      901 gcatatgatt tagctcatgg atttaccgat gaaaatccaa caacttctga aaacaagcct
      961 gtcattgatc caacacgagc tggtgcagct aatcctacac tgacagatgg aacgaattac
     1021 gcccacattg atcagtttgg agaaatcgaa aatgcaaatt tgcatgtagc tggatggcac
     1081 attgctaact ataaatacga gtatatcttc attatggatt acaatactgg gaaagaatta
     1141 gctcgagtaa gagctgatgg aatttataga tcagatgtaa atcaagctta taatacttct
     1201 ggaaatgttg gctatcatgt atcttttaac atgcgtaact tccctaataa gaaagtctat
     1261 gtcatgatgc gggcaacgaa tgatccagag ggaaacacta aaggcggtgc gcaagatttc
     1321 catgacaaac gttggtattt aaatattcct aaacgataaa aatagctcct cgttgaggag
     1381 cattacataa ctatattgac aactataaaa atcattcgat aaaatagtga tgttatcgca
     1441 tatcttcact atcacccata atagtcacac tccaagctat gcgataacag gtttgttgcc
     1501 acacattcta ctggttgatt gtttatggct ttatgtggca acaaccagta cccttagctc
     1561 agttggtcag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc tacagggtac
     1621 attaacgtag ccatttgaat cgttctgtgt tagaattttt tgaagagtat tatacaagct
     1681 aaagcttttc ttcattgcca ctcaaatgag tggctttttt atgtatcctt ttatggatta
     1741 atgaaaggat gtttcacata gttatatttc tgtatatttg aaaagtttta ctttgatttt
     1801 taaatagaaa gacatttggg ttaaattgtg agatgataat aaagaagagt ttaaagcgca
     1861 ccccaagcca cttccccata agtgtgttac gctttaaact cttttatatt tgaagctatt
     1921 aaaaggcatg ccatattttt gaaaaaaagt gagaaaaaag gcttacaatt ggagtggtag
     1981 ttaattagtg acttattttt gattttatag cactgatact ataaaatata gatatcatca
     2041 tattacacaa tcttaatact aacttaaaaa atatctcctt tcacaagtat ggtgataaaa
     2101 ttcgttccgg gctacctttt taggtagcct actttaatct ttataccttt ctggatcaac
     2161 gaaagtatac tttatatagt cataacgccg atgatcgcta cgtgcgtccg gcacgtcagt
     2221 cacgatatca aacaaaaagt atacatcttt cttcattcta gtttttgcag cagggatttt
     2281 aaagtagttc ttattagaat agtagagatt gattaataag ctatcttcga ttgctaaaaa
     2341 gaaaacttct gaattccata ctttataaaa atctttgata aatctattcg aagggtcaaa
     2401 tttaaaccat aattgtgttt ttccttccat cagcataaaa gttcacctca aaaagagtat
     2461 acgaacgaat gttctttttg tgaaggcgga atttaatata ctgaataata gaaaacaagt
     2521 acttgtgcca aattatgtgc caaaaaaatt cgaattcaac aaaatgtaaa caaatagaaa
     2581 accttctata ttaagatttc ctgcaataac aaacacaaca gaagacgtgt aatagttagt
     2641 caggaacgta caaataaccc ctgtatcctt tgcggtacag ggggttattt tgtataagta
     2701 gacattgtag tttctaaact gctatgtcct aaacgtttcg atacgctaag tatatttact
     2761 ccttgataaa gtaaaataga tgcatgcgta tgtcttagtc catcaataaa cagtcgaaga
     2821 gaaaataggg aaaaattgat tactaaagaa aaacttacta ggtcgacggt gtagttgatt
     2881 ttcatacttc aatagattcg aattaaacga tttcgattgg cttataccag tcctatccaa
     2941 cgaaagatat atcgttctta actctagcgg tataacttga agctttacgt aaagccaatg
     3001 ggaatgaact ggagatgact ttttattatt tttagtaata gctgatgggt taatacttac
     3061 aactttcctt ttcaaagtac catataaaaa aacggtgggg ttgtttagcg aaataaagga
     3121 tctaagccaa tagcttagat cctttattct atgctttata ttattttttg catgtgtgcg
     3181 aaagtatact caagcccaat cgccatttcg gaaaatcggt actgtagagc catcttcacg
     3241 gattccgtcg atatccatct tgtcagatcc taccatgaaa tctacgtggg tttgacttct
     3301 attcaatcca gcttctgcta attcttcatc ggacatttct gtaccgcctt tcacactgaa
     3361 ggcataagca gaacctagtg ctaagtgatt cgatgcgttt tcatcaaata atgtattgaa
     3421 aaagatgatg ccagattgag aaataggtga agggtcaggt acaagtgcga cttctcctaa
     3481 acgacgcgca ccttcatctg tatcaagcag ttttgctaag acatcttctc cttgttcggc
     3541 agaaaaatca acaacttttc catctttaaa agtaaatttc atacccgaga tgatggtgcc
     3601 agcataactc agtggctttg tacttgaaat gtaaccatct actcgatgac tgtcaggtgc
     3661 tgtgaacact tcttccgtcg gcatatttgc catgaatttt tctccacgag cattatagct
     3721 tccagcgcct tcccaaagat ggtttttagg caatccgata atgatatctg taccgggagc
     3781 agtatagtga agggcagaaa attgttctcg attcaattct tctgcttttt ttgctaattt
     3841 ttcatcatgc ttcttccatg ctaagacagg gtcttcttca tagacacgag tcgttttgaa
     3901 aatctgatcc cataatgcct caacttgttt ttcttctggc agttctggga agacttttgc
     3961 tgcccattgt ttaccagccg cagccacgac agtccaactg actttatttg cttgagttgc
     4021 cttgcgtaaa ttcattagtg ctttgccatt cgctgattga taagacgcta ctcgatggct
     4081 atctacacca gcaaatgcat cgggatcggc agaaacaacg ctgatcctgc ttgctccttt
     4141 ttcaagccat tcatccgctt gatcgatttt agattgtggt acattctcaa tacgatccgt
     4201 tgcagcatgt aaaagaaatt ctctttggat ctggtcgtca gtccattgaa cgataacctc
     4261 agcggctcct agtttataag cttcttgtgt gatcaatcga gcaaggggtg cctgttccac
     4321 gctgatctgt aaaacaactg tgtgtccttt ttctgtggct acgccagttt ctgcaattaa
     4381 gcgtgcatat ttttttagaa gttcattaaa atcagataac ataataaaaa ttcctcctca
     4441 ccattttttc tggtaactat tagcatgata ccatttaatt atgattcaaa caatgaggct
     4501 ttaaataaaa aaaggaggtt atttttttaa ggttaagttt catgatatat gttactactt
     4561 gctatttcag cttgtgaaga aaatcaaaaa ctaattttgc atatcaaaaa aacatgttac
     4621 aatgaaatta atcaatggtg gaagcgttat aaaaaaatta aggagattaa aaaatatggc
     4681 aagaaaaaag acgattacta gagaacagat tttggcagct gcttatgaag tagctgccac
     4741 cgatggattt acacgattta ctgcgagaaa catcgcgaac aaaatgaatt gttccacgca
     4801 accgatttat cttgagttta aaaatatgga tgacttgaga caagctcttt ttgagcagat
     4861 ctatgatcat ttacaatatg aagtgttcac tgttgagcat acagggaata cgattatcga
     4921 tcttgctttt aattatatcc attttgcaag aagagagaag aagttgtatc gttcactgta
     4981 cttagaagaa tatggtggag gaaaagagat gcagaatttc tcttatactt actttgtgaa
     5041 tacagtgaaa cgcgatccag cttatgtgaa tctttcagaa gagcagatcg aatctttgta
     5101 taatgggaca tggatcatag ctactgggat cgcagctttg atgtcttcaa gcatcatcca
     5161 tccaactgat gaacagattg aaaagatgat ccaagacagt atagatgcta tcttgaaatt
     5221 caaagaacca atcgaaatcg attgaatata ctcaaaagtt ccacaaatca gtaggtaaca
     5281 agagatgtgt caaaataagg aaaagttcgt ttttcttaca gcgtatgcat ttttaactcc
     5341 cgaagaactc ttccatgaat gcaatgaata aaagagccat acagattgaa taaatctgga
     5401 tggctctttt attgcaagta tattaaattt ttgcgactag ttctttagcg aaagcttcta
     5461 aattttcgat atcttcttct tcagcattca gatccacttt aacattttcg gctccttttg
     5521 atgcgcctgt ttttgcaaaa gcagcatcga aatcatccac cgatttgcag aattcatcgt
     5581 aaaaagtatc accagatccg cagacaccgt aaatttttcc caatagatcc aattcttgca
     5641 agtcttcata aaagtctacg atctcatcag gcagatcgcc atcatcgtat gtataagtag
     5701 ctactacgca aatatctgcc tcctcgaatt catctgcatc tacttgggta cattcgttga
     5761 tttcgacttc gatatccaga ttttcaaatg cttctgcaac aatatcggcg atttcttcag
     5821 tgtttcctgt catgctagca tatacgattt ttgctaaagc catgatgtgc ctcctcgttt
     5881 ataattattt aacaattatg aattatacca aaacatcatt gaaaagaaaa taaaacctaa
     5941 agacacctgg ggaatgtcat ttggctaaat gtatgccgct atgttaaaat gagagggatt
     6001 tgtaaaaagg agacgaaaat atgattactt taaaatcagc acgtgaaatt gaaatgatgg
     6061 cagaatctgg agctttatta gcagatgtac ataaaaatct gcgtgatttt ataaaaccag
     6121 gaatcacaag ttgggatatt gaggtatttg tcagaaacta tatcgagagt catggcggaa
     6181 ttgctgcgca aattggcttt gaagggtatg aatatgcgac ttgtatcagt ataaatgatg
     6241 aaatttgtca tggattccct cgtaaaaagc ctttgaaaaa cggtgatttg gtaaaagtcg
     6301 atatgtgtat cgatttgaaa ggcggcattt ctgattcttg ttgggcctat gtagttggag
     6361 aatctacacc tgagatcgac cgattgatgg aagtaacgaa gaaagctttg tacatcggta
     6421 ttgagcaagc acaagtaggg aatcggattg gtgacatcgg tcatgctatc caaacttatg
     6481 tagaaggcga aaatctagcg atcgttcgtg attttattgg tcatggcgtt ggtcctacga
     6541 ttcatgaaga accagcagtt cctcattacg gagaagctgg aaaagggttg cggttgaaag
     6601 aaggcatggt tatcacgatc gaacctatgg ttaataccgg aacttggaaa atgaaaatgg
     6661 atcctaacgg ctggactgcg tatacaagag acggcggact ttcttgccaa tatgaacata
     6721 cattggctat tactaaagat ggtccaagaa ttttgacatc acaaggagaa gaaggcactt
     6781 attgatctat ccagtcaata ggtacgggag aggtacatga aagtttggaa caaaataaaa
     6841 caaaatgaaa atctgatgcg ctttattgag acgactcaaa agcgcatcac tgattcagaa
     6901 atgagtacga cctctgtcgt cgttgcttat tatttactct tgtctttatt tccattgatt
     6961 attgcttttg gtaatatttt accgtttctc cacatcgatc aagagactgt actgacctat
     7021 ttacgagaag tgattcctga gaccgtttac cagtttatcg gtcctgcaat caaagacctt
     7081 ttgacacaaa gttcaggagg cttgttatcc gtttctgcat tagcggcttt atggtctgca
     7141 agtcaaagta tcaatgcttt gcaaattgcg atgaataaag cgtatggcgt agaaaataga
     7201 aaaaattttt tgatcgtccg tttcttctca ctaattgtca ttgtcttgtt catgattgct
     7261 attagtgggg taactatcgt tcttgggttg ggacagctga ttttggatgc tattcagcca
     7321 atcgtacaaa tacccgtgaa ctttatcgat cagttccaaa ctttgaagtg gccaatcaca
     7381 ttggtagctt tatttgtcat catgttcttg atttatttaa ttgtccctaa tgctcagttg
     7441 aagttgaaga cgatcattcc gggcacgatc ttcgctactg tcggctggat gctgttatca
     7501 caagtgttta gtatctatgc taggtatttt gcaacgagga tcagcggtta tcagatcata
     7561 ggaagtttta ttgtactcat gctttggctt aattttgctg ctacgatcat cattttgggc
     7621 ggaatcatca atgcagttgt tcaagaatac gtgacgggtc atcaaatcaa aaaacgtcga
     7681 gatccaagcc gaaaatggtt caataaattg aaaactaaat tttctcataa aaaaaagtag
     7741 aaacaagagt tcttattgta aatttatatc agtaatttat aataattatg actcttaatt
     7801 aaagtaggtg cccatatgct tgtttctttt agtatggtta taagattttt tctgacaatt
     7861 ttattatcac tgatattaac acctgtattc aaaatcattt cagtacaaac aggtatggtc
     7921 gacaaaccaa atgaaagaag aataaataaa gttccaatgc cttcagcggg cggactgcct
     7981 atctttattt catttgttat atcgacttta ttcttattcc gtaaaattat ccctcaatcg
     8041 tatattgtac cgatcttgat tgcttcttta gtaatcatag tcacaggagt gctcgatgat
     8101 aaatatgagc tgacacctaa acaaaaaagt atagggatct tgattgcttc tcttattatt
     8161 tattttgtag cagatatacg tattgattcc ttcacgcttc cttttattgg atatatccaa
     8221 ctaggctggc ttagttttcc cgtaacgatt ttttggatct tcggtatcac gaatgcggtc
     8281 aatctgattg acggtttgga tgggctggcg gcagggattt cattgatcgg tttaattacg
     8341 ataggaatca ttggatattt tttcctccat gcttctacag tgtatattcc agttgttatt
     8401 ttctgtcttg tagcaagtat tatcggtttt tttccttaca atttttatcc ggcaaagatt
     8461 tatttaggcg atacaggagc tctattccta gggtttatga tggccgtcct ttcactacaa
     8521 gggctgaaga acgtgacttt tgtttcatcg atttctttgc tgatcgtcat gggagtgccg
     8581 gtaacagaca cgttttttgc tatcattagg agaaaagcaa accgtgtttc tttttctaca
     8641 gcagataaaa aacatcttca tcaccgacta atcagtttag gctttactca taaaggtgct
     8701 gtcctgacga tttatgcgat ggctttgatg ttttctttca cagctatggt catgaattat
     8761 actggaagaa tcggaacgat catattgatt attgccatgt tgtttgctgc aattttatta
     8821 tttgaattga ttggtctgat caatgagaaa catcagttta ttttaaaaac attgcgattt
     8881 ttagggaata aagagtaccg tacgcaagta aaacagaaat atttgaagaa atggaaccgt
     8941 catatagatg aataacaaat taaaccagcc gatccttatt agtattgtga cggcaaacag
     9001 tgataaaatt tttcggacac tagataattt tatttcaact gtaaaagatg aaacagcagt
     9061 aaaaatccga atttttgaca acaattcact tcccgagtac aaaaaaagac taacagagta
     9121 taggaaatat ccctacatcg atatctattt tcatgatgaa aattccggat ttggttatgg
     9181 acataatcac aatctgatag ctagcgattc tcgctatggc attatttgta acccagatat
     9241 tttagtggat gaagagacag ttacagcatt ggtcttgtta ttgaaagaac atccggaatg
     9301 tgcgatgtta gcacctaaga ttcttaatga agatggaaca actcagcacc tcatccgtga
     9361 gcagctggct gtttttgatt acgttttgcg ctttgtgcct ttcaaatggg tcaaaaaaaa
     9421 gtttgacaaa cgactggctg tgtttgaatg ccgaggattg cctactgatg ctaatagtta
     9481 tgtacggatg atctcaggta gttttatggt agctgatatt gataaattta aagagataaa
     9541 ggggtttgat gagcgtttct tcatgtactt tgaagacaac gacttgtgtt tgagttttga
     9601 aaaagcaggt tacaagttat tgtacacacc cttttatgca gttatccatt tttacgggaa
     9661 gggtgcgcat cgaaatgcaa aactgtttcg cgtgtttttg acttctatga tgaaattttt
     9721 caataagtgg gggtggcgtt ttttctgatg aaaccagaaa tattagtagt cgttgtgctt
     9781 tatcagcaac tattcagtca atctccagct tatggaccat taagcaaagc acttagcgaa
     9841 aagcaaattc agcttattat ttacgataat agtcctcaaa ggcagcaaaa tgagctgttt
     9901 gaaaaagaaa atatcgttta tcatcatgat ccgcaaaatc ctggtttagc ggtggcttat
     9961 aattttgcgt tgtctcaagc agatgaagga acacgttgtc tcgtcactct ggatcaggat
    10021 acgaggctag tcgacgatta ttttgaacta ttgcgtaaag taacctttac agatgaatgt
    10081 gttgctgcag ttccgatgat tttttctggg agccgacaag tttctcccct atattcagat
    10141 cgttatatca atcgtacagc tcaagcagta gaagttgaag gcccaacagc tgaacgaatc
    10201 atggcaatca attcaggtgt tgcctggtct gtcaaatttc taaaaaagat tggcgggttt
    10261 aatcctgctt tttctttaga ttttttggat cattggctgt tttggaaagt ggatcagttg
    10321 gaaaaaactg tggagatcct tcctgtacga atggaacatg atctttcggt tttagactat
    10381 gaaaaagttt caagtaatcg ataccgttct attttacaag cagaaaatcg attttatcat
    10441 gaatatgatc aaaggcattt atccagtcac cgacgacaat tattgttaag aacagctaaa
    10501 cagttcttga ccgtcaaaaa ccggcatatc tggcggatga ctttgcgctc atatgttaag
    10561 aattggaagg tgtgaattcg tgcgttcggt ttgtatagct acctttaatg gaggcagata
    10621 tttaagagag cagttagata gtattttatc tcagctttca gcagaagatg aagtagtcat
    10681 ttctgatgat gggtcagtag atgatacatg ggatatatta actgaatacg cagaaaaaga
    10741 taagcgaatc cagctttttt cggggcctcg tcaaggattg atcgctaatt ttggttatgc
    10801 gatccagcag acgaaaggag atctaatctt tttggcagac caagatgatg tttggttgga
    10861 gacaaaagtg aaaaagatca ctgactattt tgagcagaat ccggatcagc tagtagtagt
    10921 ttctgattta atcattgtgg acagcgagct gcaagagatc catgattcgt atttttcgtt
    10981 tcgaaattcc aaagaaggat ggcttaataa tgtgataaga agtcactata ttggtgctgg
    11041 tatggctttc cggtcttctt taaaacccga tattttgccg atcccgtcag aagtgccgat
    11101 gcatgatatg tggattggtt tgctgggagg aaagaagact gggttcctaa gagaaccgtt
    11161 aactctgtac cgaagacatg atttaaacgc gagtgagatt gaaacacatt ctaaattacg
    11221 gcaaaaaatt tcttggcgtg ttcatctgat tacggcgttg atcaaacgaa aatggtttaa
    11281 acgttgataa aagatgttta aatccttaat atttccatga caaatataac aattgatgag
    11341 ataataacaa agtgaaattt gaaatcaaaa aggagagcag atatccatga agggaatcat
    11401 tcttgctggg ggcagcggaa cacgtctgta ccctttaaca aaggcaacat cgaaacaatt
    11461 gatgccgatt tatgacaaac caatgattta ttatccaatg tctactctga tgttggcggg
    11521 aatcaaagaa attctgatta tttcaacgcc acaagataca ccacgtttca aggaattatt
    11581 tggaaacgga aatgatttag gactgcagat cgaatatgca gtacaagaaa gtccagatgg
    11641 attggcacaa gcgtttatca ttggagaaga atttattgga gatgatagtg tctgcttggt
    11701 attaggggac aatatttact atggtggcgg tctgtctaaa atgttgcaac gagcagcttc
    11761 aaaagataca ggcgcgacag tatttggcta tcatgtcaat gatccagaac gctttggtgt
    11821 agtagaattt gatgagaata tgcaagcttt gtcgattgaa gaaaagcctg ctcagccaaa
    11881 atcaaattac gctgtaactg gcctttattt ttatgacaat gaggtaattt ctatcgctaa
    11941 aggtatcaaa ccttcagaac gtggagaact agagattacg gatgtcaata aagcatattt
    12001 ggataaagga aaactatccg tagaacttat gggacgcgga tttgcttggc ttgatacagg
    12061 aacacatgaa tcattgcttg aagcatctac ctttatcgaa acaattgaaa aacgtcagaa
    12121 cttaaaagtg gcttgtttgg aagaaattgc ttaccgtatg ggctacatcg ataaggaaca
    12181 attgctggcc cttgcacagc cattgaaaaa aaatcaatac ggtcaatatt tattgaattt
    12241 ggccgctgaa taaggagtcc ttacagatga aagtaacaga tacaaaatta acagatgtca
    12301 aaatcgtaga aatggacgtc tttggcgatc atcgcggttt cttcacagaa agttattcaa
    12361 aagcaaaatt tgcagaacat ggattgaaat atgactttgt tcaagacaac cattcactat
    12421 cagctgaagc tggtgtcctt cgggggcttc atttccaaaa aggagaagct gcacagacaa
    12481 aattgattcg ggtagtcact ggagcagttt tagatgtagt agtggatatc cgcaaaggta
    12541 gcccgactta tggtcaatgg gacggattta tcttatctga acataatcat cgacagttgc
    12601 ttgtacctaa aggatatgcc catggattcg ttactttgac accaaatgtg aacttccttt
    12661 ataagtgtga taattactat aatgcagaag cagatggggg catcgcattt gatgatccag
    12721 atttagcgat tgattggcca attgatccat caagagcgat tatgtcggaa aaagatcacc
    12781 gtcatccgac attaaaagaa tttgaagcag aaaatccatt tgtttacgga gaaatctaag
    12841 aattaaggag aaattttctt atgaaaaaca tcattgttac cggaggtgcc ggattcatcg
    12901 gctctaattt cgttcattac gtggtaaaca atcatccaga agtgcatgtc actgttttgg
    12961 ataaactgac ttatgcagga aacaaagaga acttggccgg acttcctagc gatcgcgtag
    13021 aattggtcgt aggagatgtt gcagatgcag aattagtgga ccgtctagta aaagaagcgg
    13081 acgcagttgt tcattacgcg gcagaatccc ataacgataa ttcattaaaa gatcctttcc
    13141 catttgtaca aacgaatatc attggtacgt atacactttt agaagcttgc cgcaagtatg
    13201 atgtacgcta tcatcacgta tctactgacg aggtttacgg cgatcttcca ttacgtgaag
    13261 acctgccagg acatggggaa ggcgaaggag aaaaattcac tgcggaaaca ccatataatc
    13321 cttcaagtcc atattcttct acaaaagctg gttcagatct gttagtaaaa gcatgggtgc
    13381 gttcttttgg cttacgtgca accatttcaa actgttcaaa caactatggt ccttatcagc
    13441 atattgaaaa atttattcct cgccaagtaa cgagtatctt aagcggtatt cgtccaaaat
    13501 tatatggcga aggaaagaat gttcgtgact ggatccatac gaatgatcat tcttcagcag
    13561 tgtggctgat tttgacgaaa ggcagaattg gcgaaaccta tctgatcggt gcagacggtg
    13621 aagaagataa taagaccgtg atggaattga tcttagaaat gatgggccaa ccaaaagacg
    13681 catacgacca tgtaaacgac cgcgcagggc acgatttgcg ttatgcaatc gattcgacaa
    13741 aattgcgaga agagctaggt tggcagcctg agtttacgaa cttccgtgat gggttggctg
    13801 acacgatcaa atggtacgaa gaacatgaag actggtggaa aaaagaaaaa gaggccgttg
    13861 aagcagcata tgccaaaaat ggacaataat acagaggaaa tttcactgta ttaatggaaa
    13921 aacacatgtg aggcaggcgc tcgcctgtct cttttttaaa ataaaaatca aggagcggat
    13981 aaccatatgt ttttattaac tggaggaaat ggacaattag gtacagaatt gcgccattta
    14041 ttagatgaaa aaaatctgcc atatgtttca acagatgcaa aagacttgga tatcacagat
    14101 gctgagaaaa caatggctta tattacagaa ttaaaacccg atgttatttt ccattgcgca
    14161 gcttacacag cagtagataa agcagaagaa gaagcaaaag aattagatga gaaaatcaat
    14221 gtcgatggca caagaaatgt agcacttgca gcaaaagctg tgaatgcaca attcgtctat
    14281 atcagtacag actatgtttt cgatggaaaa aacaaaaatg tagaatacga agtagacgac
    14341 caaacgaatc cactaaatga atatggtcgt acgaaattat taggcgaaaa agcagtagaa
    14401 gagattttag aagactatta tatcatacga acttcttggg ttttcgggat ctatggacac
    14461 aatttcgtct tcacgatgca acgcctagcg gaaacccgcg acaaactgac tgtagtaaat
    14521 gaccagtttg ggcgaccaac ttggacacgt actttggcag aatttatggt atatgtcatc
    14581 gaagaaaaag caccatttgg tatttatcat ttgtcgaacg aaaatagctg ttcttggtat
    14641 gagttcgcaa aagaaatatt gaaagataca gatgtagaag ttgcacctgt tacgtcagaa
    14701 gaatttccgc aaaaagcaac acgtccgcag tattcagtca tgagcctgaa aaagacagaa
    14761 gcgttaggtt ttgtcatacc aacttggcaa gaagcacttg cgcaaatgct ggaagctgcc
    14821 aaaaaaatga ataagtaatt tcctttttat caaatagaat ttggagcatg atatggaaaa
    14881 acaaacaaga agtgcacgac gaaaagaaaa gccaaaagcg aatcaggcag attcgaattt
    14941 ggtgcttgac ctgtttctaa aactccgcta tcttattggc gttttagtca tcgtggtcat
    15001 cgttactttt aatttaaacg gaagttcact tggtgtttgg gataaatatg tgtcgcaaag
    15061 agacgatggg aaaaaaactg atgtgatttt tggacagaat cgggaagtgc ggtcagacga
    15121 atggctggtg cagacacctt tttacctctc acaagctgaa gaggactttt cgttggtgaa
    15181 cgaggattat tcattaaacg gacaaaacat gatcattgcg tataattctc ctgtaaagga
    15241 tattacggtt atcggaaaac cattcaactg gggattcttt ttcctcggaa gagatcgagg
    15301 actttccttt tattgggcga tgaaattagt cgtcatggtc ttgcttggat tcgaagtact
    15361 gatgatatta acgaagagga aaaaagctct atcgctaatc ggtgcatttg cgctgacatt
    15421 ttctccagca gtccagtggt ggttcatgca acatgtgggc gatttgattt tctttacttt
    15481 gggactgatg attgcttttt atcattattt ctacaatcat gataaaaaat ggctacgaac
    15541 gttgatgatg cttttggtgg ttattttcgg tattgggttt attttagtga tttacccagc
    15601 ccatcaagtg atgctggcgt acttgctgat tttttatttt gttggcctgc ttatttacta
    15661 tagcaagaaa gtttcatggg atctgttgga tgtagtgttg attggagggg cagttttatt
    15721 tattggcgga gtcatggttc atttctggct aacgtcaaaa gacgcattgt tagcttcttt
    15781 gaatacctta tatccaggaa aacgggtaag tactggagga aagtggacga ttggcgaatt
    15841 tttttctttc cttacaaatt ggaaaattcc ttttgaagat atcaactatt cgaataactc
    15901 tgaagtggcc ctgttctatc acttttttcc aactgtattc ctagcaagtc catttgtgtt
    15961 atttggcaaa aaagatagcg aacaaaagtt actgggacgt attttgatga ttttttgtct
    16021 gttttctatc ttttggatta ccgttgggtt gccaaaatgg ctagcagaaa tcactctgct
    16081 gtcttatgtt cctccattaa gagccatcct tacttttagt tttgcggctt gtttattatc
    16141 gatctggttt atcgcttata tttggagaga agatgttatt cctatttggt ataaattcat
    16201 tttgttggca gtaaatgcat ggtcttattt ctatgcgatt acgcattcga aaatggataa
    16261 ttatttttcg gattttgaaa ccatcgcagt tgctgtgttg ggaacagtga ttttagcttt
    16321 tgcattattt ggctggagac gcttgtttta cctcgctttt gtcgccttag ttatcgtatc
    16381 tggctttttc gtcaatccag tcgtagaagg tacaggagcg atttttgaaa aaacactggc
    16441 aaaagaaatc caaaaaatcg atcaacaaga tcctggtaaa gtttggttgt ctgaagatga
    16501 attatataac ttcaccccaa cattgggagt gaaatccttc aatacagtac gcttttatcc
    16561 agatatagct gcatggaaga aaatcgatcc gaaagaagaa tacgagaagt attataatcg
    16621 gtatgctcat acaagagctt ttatcgctaa ggaagataca aagttcattt tagatcgtcc
    16681 agatatgttt tcggtcacgt tgaattttga agacgcagaa aaattaggga tcgactatgt
    16741 gatcagtaaa cgaccattaa ctgattacaa ccaattatat gaagcgcagt tcacgcagct
    16801 atatggaccg gataaagacg gttatatgat ttttaaagta gaatatccgg attatccaga
    16861 tgtaccacaa acacaaactc aggaaaatca gctagtcgta cagtaatagg ctagctgaga
    16921 ataatcctga aatattagta gaaaggagag tgaagataat tcaagcaatc gtacaaaaat
    16981 ttgtcaacaa aatgagtgtc ggtttcttgc ttttgttgct gacgctagtc ttttttgttt
    17041 ggacagcagg ggtaggtttt ccagcaactt tgtttatata taacaatagt tcattactta
    17101 tcgcttttag tgtggctatt ttgctcattt taaatgttta taaagcaaaa ggcgtcgatt
    17161 ttctttatct aggtgttgcg cttgcccttt tcattttctt ttcttacttt cgggaattaa
    17221 gaaatgagtc tttatttgga gacttactgt ttcctttgat tattttattt tgtttagtaa
    17281 ttaaatggat cgagtggaca aaatgggatc gcggtattta tctgattgtc tttacggtct
    17341 tcctcggaat cacgttatat cgtgtattta cagagatcca agtaccagaa ggacaaagca
    17401 tctgggctcc aggcaattcg ctttctgata tttggatcaa tacgaataca atcggaagtt
    17461 ctttgatgac tcttgcttta ttgatcagtg gatttgccag ttcttttgaa cgatggtatg
    17521 ttcgaatcat cggtgggata gcagtcgttg cagccttttt aggtatttgg gtctgccaat
    17581 ctagaggtgc attagtcgcg ttgattgttt ttgcgatatt ggatctttta cctaaatcgt
    17641 tgatgcgtgt cattcgtgcg ccatttattg cctacacggt tacgattctt ttagctttgc
    17701 cgatttctta tctggcggct gtctctgaaa aagtcaattt gtttaccggt cgagaagata
    17761 tttggcataa attctatcag acgctaggag aaaaatctga acaagtttta ctaggaatga
    17821 aaacatttat cttccagcga ggaaaccaat ttttaggaaa ccacaatagt tataattcta
    17881 ttttgaatat ctatggattg ataggatttg ggattgctgc tttgctgctt atccttttta
    17941 ttggtcgctt aacgttgaaa gcagatttat ccaacgggca gatgactttt atctgggcct
    18001 tttttgcggt gatgatgcag tcatttatgg aggatacatt gacttcatac ccatgggttc
    18061 cgattattta tatcctgttg gctatggccg ttcatcgata tgatgaacca gaagttacgg
    18121 aggaattcta tgttatggaa gaggcatatg acgatatgac ttatgatgat acatcttatg
    18181 aggaacaacc agatagcgct cattcttcca ggatccaacg ctatcattga taggcacaaa
    18241 atacgagaga ggctgtgaca accgtcgcag ccttttttgg tttattgcaa ttgtctagca
    18301 tcttctgtaa aatagaaacg ttagagaaaa tcttgtatca tagaaaatta agaaagaaat
    18361 aagaacgcag ctcggtacca aaaatatggt aaaatggcac ttgactgtaa ttcactgaaa
    18421 atcgcttgga ggaacacaaa tgtttaaaga tttgtattta tttatgaagg acatttatca
    18481 gaacagaaaa ttactgctac agttttcgat caatgacttc aaatcaagat atgcaggatc
    18541 gtttttagga atcttatggg cgtttatcaa tccgctattt actgtattga tttattggct
    18601 ggtatttggt gttggactga aagcacaaat gatcgatgca aaatacccat ttatcgtata
    18661 tttagttacc gggatgattc cctggttctt cttctcagat gcatttgcat caactacggt
    18721 tgtttttcgg gaatatactt atttagtaaa gaaagtcgta ttcaatattc gtatcttgcc
    18781 cacgacgaaa atcctatcca atctgtacac ccatttattc ttcattctga ttggcatagc
    18841 tgtcgcgctt ataaatggta tatatccttc agcaatgtct ttacagctga tttattattt
    18901 attttgcatg tgtgctttct tgacaggatt gacttggctg acggcatcga tccaaccatt
    18961 tttacctgat atcatgcaat taattacgat cgtgctgcag ttgatcatgt ggacattacc
    19021 gatattatgg agccctaatc agtttgattc aggtcttgta agcatattga aattaaatcc
    19081 gctgtactat gttgttcaag gttatcgtga gtcattttta agtgaagctt ggttctggga
    19141 gcatggaaca tatactttgt atttctgggt tttcacgtta gtaatgttcg taatcggctc
    19201 tgcagtgttc cgtagattga aaccacattt ttcagatgtg ctgtaaggag aatagctatg
    19261 acagaatatg caattagact aaaagatatc acaaaatctt ataatatgta cgcaaaacct
    19321 tcggatcgat ttcgtgaagc cctcaatcct tttaagaaat cctatcatga tgtattttat
    19381 gcgttgaaaa acgtgaatgt agaaataaaa aaaggtgaga tgatcggttt cgtgggagaa
    19441 aacggatcgg gaaaatctac aatgttgaaa atcattacgg gagtactgac accaacatcc
    19501 ggcacgatgg aaatcgaagg aaaaatctca gctttgctag aactaggatc aggattcaat
    19561 cctgagtatt ctggctatga aaatatctat ttaaatggaa tggttctagg attttcaaga
    19621 gaagaagtcg atgaaatggt cgatgatatc attgaatttg ctgacatcgg cgaccatatt
    19681 tatcaacctg taaaaaccta ttcaagtggg atgttcgttc gtctagcttt tgctgtagcg
    19741 atcaatgtga atcctgatat tttgattgtg gatgaagcat tggcagtagg agatcttgaa
    19801 tttcaactaa aatgtatgga aaaatttaca gaaatcaaga actcgggaaa gacgatttta
    19861 ttcgtttctc atgatattag ttcgattcgc cgtttttgtg atcgttccta ttggttgaaa
    19921 aatggaaaag ttgtcgaata tggtgatacg atggaagtaa cgacgaatta cgaaaacttt
    19981 ttgaagaaaa aatcagttaa aacagtagat cgaaataaaa accaagtaga acgcttcgca
    20041 gctccagata tcgtagacgt gacgaaagcc gaattgttgg ataaagataa aaatccagtg
    20101 gatatgctgg aacaaggaga aaaactatac gttaaagtaa cctatgaagt aaaagacgat
    20161 acaatcaaaa atccagtttt aggaattgct ctgcgtacag tcgacaattt ttatgtgtgc
    20221 ggactcaata ctctactaga tggtatcaag atcccttgga aaaaaggtga gaatatcttt
    20281 tatctggagt atgaaaagtt aggtttgtta gctggtgaat attattttga cgttgcggtc
    20341 tttgaagaaa atgcaacggt tcctttggta tacaagacaa aatacatgaa cttgtttgtc
    20401 agcggttctt atatcggaga aggcatcgtg gtcttagacc ataaatggga agaagggact
    20461 catagcaatg aaatatgatt ttgaaatgga cctagatgaa caaagcagtg tgggaaaaat
    20521 tgccgcacag atcaaaccag gaagtaaagt tttagagttt ggtcctggaa acggccgatt
    20581 aacgaaacat ttgatcggag caaaacaatg tgaagtgagc attgtcgagc tagataagga
    20641 attgttcgat tttgtcagcg agtttgccca agatggattt tatggagata tcgaaagttt
    20701 tgaatgggca aactattatg ctggacaaac atttgattac gttttgtttg ccgatgtttt
    20761 agaacatttg gtagatcctg gaaaaacgtt gaagaaagtt agagaatttt tgaatgaaga
    20821 aggagaaatt ctaattacat tccctaacct tgcgcataat tctgtcatga ttgatttgtt
    20881 caataatcaa ttaccatggg cttcttatgg tttgctagat gaaacccata attcttttta
    20941 tactcatgat ggcttccaaa aagtttttga aaaagcagga ttatacatca atattgaaga
    21001 ttatttgtac ttagctgtag gtgatacaga attaaaatca acttatgaag aattgccgga
    21061 agctgtacgt tatgatttca aaatgcgacc atttggcgaa gtctaccaat acttcttctc
    21121 attgatgaaa catccagtag cacaaagttc cattgcgcag ccgcaaaatt ctaattatgt
    21181 gaaagtatta gaagtaatcc agcaaacgaa acaagatgaa ataattcaac aaataccatt
    21241 caataatttc acaggggaaa atgagacact aagtttccat gtatcagaat tagcagaacg
    21301 aatggtgttt cgcttcgcgc agcaacctag ctttatcgaa ttcagcgcag aagctgctgg
    21361 agaaaaactc acatttatcg attcaaatgc tgtagtcaaa acagtaaatg attgttattt
    21421 gtttgatggt aaagatttac cagagttctt tttaacggat attgcaggga aagaagtgac
    21481 tatccattgt cactatcgtt ttatcggaga attgacacca acaatgaaag aattgctgga
    21541 aacaatccgt ccaatggctg aagttacaaa gcagctttct gagaaaaatg atgaattaga
    21601 aagagaaaat cattatctta ttgagaataa tacaagatta gatcagacgt tgaaaacaac
    21661 cataaatcgc tattgcacgt tgttggaaag tgatgaatgg acaatcaaac atagattagg
    21721 gcgacgtaag aaagaaacat cgaaaaaaat ccaagaaaaa gagctttctc tatgtattga
    21781 cgaaaaaatc tgggatgcag aaacaaagat attgaaaatc atcgggtggg gaatcgctaa
    21841 ttcggatcgc caaccattgt cctataagtt atcagccgac caatcaccat tttttgaagc
    21901 aattcctgtt ttacgagaag aagtcaatca agcaaaacag ctagctgaag gagcaaaagc
    21961 aggatttgaa ctgcggatcc tttgcgagaa ggaacgttca ttcttagttg aagcagtggc
    22021 tcaaaatggt caatcatgga tcattgaaat gtaaataatg attaacttat aaagataagg
    22081 agtaaacgaa tcgtgcaaaa aaaagaaatt gccgtattta tcgatcaaat cactcgtgaa
    22141 cgggccactg gcgatttgct tattgtgggc tgggcaattg atgaagtgac caaagaaatc
    22201 cctacgataa aggtagaaaa agaaaatgtg attgctgaag caacacatgt cgtaagattg
    22261 gatatcaatc atttatataa tcttgatgtt aagacccaaa gcggttttaa ggtacgttta
    22321 tcagggaaaa tgagaggaaa agcaatctta gacttccaaa cagcaagaca tcaaaatggc
    22381 atagctgtga aattaaacgg taaatatcct tatgatgacg gcattgaatc ttcatgggaa
    22441 agaaaaaaaa gattactgaa aaaagggata aattatgcaa ggactcatgg cgtaaaaaaa
    22501 gcaatccgcc gggtcaaact ggaattgaaa ccaggatcga tcgactatgc agagtggatc
    22561 agtcgtcatg agaaacctga tctgaaagag caaaggaaag aagtacaagg atttgcctac
    22621 cgcccattga tttccatact tatgcctgtc tataacgttg aaatcaaatg gctcgaaaaa
    22681 tgcattgatt cggtacttga tcaaacgtat gatcactggg aactatgtat cagtgatgat
    22741 gcttctactg atccagctat ccgaaagtgt ctagaatcct atcaagcaaa agatgataga
    22801 attaaagtcg ttttccgaca agaaaatgga cacatcagtc tggcaactaa ttctgcattg
    22861 aaaatggcag aaggagagtt tatagcgctc ttagataatg atgacgaatt acctccattt
    22921 gccttatatg aagtggcaaa agtgctaaac gtacatccag aactggattt gatctacagt
    22981 gacgaagata aaatcgatgc agatgggaat cgctttgacc cgcacttcaa agcagactgg
    23041 tctcccgata cattgatggg aaataattat atctctcact taggcgtata tcggacaagc
    23101 attgttaagg aacttggcgg tttccgtaaa ggatatgaag gctctcaaga ttatgatttg
    23161 gttcttcgtg tgacagaaca aattcctgca gaacacattt accacattga ccgtgtcttg
    23221 tatcattggc ggacgatccc gggatcaact gcaagcaatg gagaagctaa aagctacatc
    23281 tatgattctg gagtgaaagc attgacagat gctctatcta gaagaaatat caagggaagc
    23341 gtacatcctg gcagaatttc tggtttttat gaaatcactt atgatgtttt gcaagaagac
    23401 ttggtcagtg tgatcattcc aactaagaat ggctatgaag atctaaaaac ttgtgtggat
    23461 tcgatcatcg aaaaaacgtc ttatccaaat tatgaaatca ttattgcaga taatggaagt
    23521 acagatccta aaatgcaaga attatttgca gaatacaagc atcagctgaa agaccgattt
    23581 atcgtcgaat taattgacat tccattcaat tattcacgta tcaacaatct ggcagcagaa
    23641 aaagcaaacg gcaaatactt tttattcttg aataacgata cagaagtgat tgaacctgac
    23701 tggatgacag cgatggtttc ttatgcacag tttgatcgaa tcggctgtgt aggagcaaaa
    23761 ttattttatc cggatgatac aacgcagcat gcaggtgtat tattagggat cggtggcgtt
    23821 gcaggacatg cattgaataa ctatgatcga acacattgtg gttactttgg ccgattggtc
    23881 attgacgtca attacttagc agtcactgca gcttgtatga tggtcaaggc agctgacttc
    23941 aatgctgtca atggatttga tgaaatatta gaagtagcat tcaacgatgt tgacttgtgc
    24001 ttgaaagttt atgaactggg tcgttacaat gtctatgcac atcaagcaga attgtaccat
    24061 ttcgaatcta aatcaagagg ttatgaagat acaccagaaa aacaaagacg ttttgctggg
    24121 gaaatcaaaa aaatgcaaga taagtggcct tcttatattg ctcatgaccc attttataac
    24181 gataatctaa ctaaagaagg aatcggcgat ttttcgttga gacctgattg attaaaagaa
    24241 ctgtattttc atttttatta atgaaaatac agttctttta atttaatt
//
LOCUS       DACDLM010000040        24272 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.040, whole genome shotgun sequence.
ACCESSION   DACDLM010000040 DACDLM010000000
VERSION     DACDLM010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24272
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.040"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..572
                     /locus_tag="IV356_001678"
     CDS             <1..572
                     /locus_tag="IV356_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAP9015366.1"
                     /translation="ASRIAIMSEGRVIQFDTPENILRHPANDFVEELIGEDRLLQAKP
                     NATRVGEVMLNTAITITPEKSLQEAIKLMREKRVDTLLVTDNSNVLKGFIDVETLNKK
                     RGKVSSVGDILNKHVFYVKESAYLRDTLQRILKRGLKYVPVVDEQNKVVGILTRASLV
                     DIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            576..1217
                     /locus_tag="IV356_001679"
     CDS             576..1217
                     /locus_tag="IV356_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9015367.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            1214..2131
                     /locus_tag="IV356_001680"
     CDS             1214..2131
                     /locus_tag="IV356_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP9015368.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            2128..2799
                     /locus_tag="IV356_001681"
     CDS             2128..2799
                     /locus_tag="IV356_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9015369.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(3340..3828)
                     /locus_tag="IV356_001682"
     CDS             complement(3340..3828)
                     /locus_tag="IV356_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HAP9015370.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(4029..4295)
                     /locus_tag="IV356_001683"
     CDS             complement(4029..4295)
                     /locus_tag="IV356_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAP9015371.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(4295..4558)
                     /locus_tag="IV356_001684"
     CDS             complement(4295..4558)
                     /locus_tag="IV356_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAP9015372.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            complement(4551..4823)
                     /locus_tag="IV356_001685"
     CDS             complement(4551..4823)
                     /locus_tag="IV356_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015373.1"
                     /translation="MYWCCCIDSQALDSTFAKDDTLLPITLRLATASRKGVRSERGQR
                     SSLKRGLFLYVKKRKSLLNLSALLYFFDVLNQVRYNYIRKRRRDNG"
     gene            5034..5219
                     /locus_tag="IV356_001686"
     CDS             5034..5219
                     /locus_tag="IV356_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP9015374.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(5361..7184)
                     /locus_tag="IV356_001687"
     CDS             complement(5361..7184)
                     /locus_tag="IV356_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HAP9015375.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(7782..10487)
                     /locus_tag="IV356_001688"
     CDS             complement(7782..10487)
                     /locus_tag="IV356_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HAP9015376.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(10793..11740)
                     /locus_tag="IV356_001689"
     CDS             complement(10793..11740)
                     /locus_tag="IV356_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HAP9015377.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            11930..12199
                     /gene="rpsN"
                     /locus_tag="IV356_001690"
     CDS             11930..12199
                     /gene="rpsN"
                     /locus_tag="IV356_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAP9015378.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(12375..12737)
                     /locus_tag="IV356_001691"
     CDS             complement(12375..12737)
                     /locus_tag="IV356_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAP9015379.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(12748..13869)
                     /locus_tag="IV356_001692"
     CDS             complement(12748..13869)
                     /locus_tag="IV356_001692"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HAP9015380.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(13885..14235)
                     /locus_tag="IV356_001693"
     CDS             complement(13885..14235)
                     /locus_tag="IV356_001693"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HAP9015381.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(14365..15876)
                     /locus_tag="IV356_001694"
     CDS             complement(14365..15876)
                     /locus_tag="IV356_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAP9015382.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(16198..17550)
                     /locus_tag="IV356_001695"
     CDS             complement(16198..17550)
                     /locus_tag="IV356_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HAP9015383.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLAATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(17703..18779)
                     /locus_tag="IV356_001696"
     CDS             complement(17703..18779)
                     /locus_tag="IV356_001696"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HAP9015384.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            18975..20720
                     /locus_tag="IV356_001697"
     CDS             18975..20720
                     /locus_tag="IV356_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HAP9015385.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(21000..21437)
                     /locus_tag="IV356_001698"
     CDS             complement(21000..21437)
                     /locus_tag="IV356_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HAP9015386.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(21421..22794)
                     /locus_tag="IV356_001699"
     CDS             complement(21421..22794)
                     /locus_tag="IV356_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015387.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(23116..23604)
                     /locus_tag="IV356_001700"
     CDS             complement(23116..23604)
                     /locus_tag="IV356_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP9015388.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(23626..24228)
                     /locus_tag="IV356_001701"
     CDS             complement(23626..24228)
                     /locus_tag="IV356_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAP9015389.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         6959 a         5163 c         4488 g         7662 t
ORIGIN      
        1 tagcaagccg tatcgccatc atgagtgaag gccgtgtgat ccaatttgat acaccagaaa
       61 atattttacg tcatcctgca aacgatttcg tagaagagtt gattggagaa gatcgcctac
      121 tacaagccaa gccaaatgcg acaagagtcg gcgaagttat gctaaataca gcaatcacga
      181 ttacaccgga aaaatcatta caagaagcaa tcaaactgat gagggaaaaa cgtgtagata
      241 cgttgttagt taccgataat tcgaatgtat taaaaggatt tatcgatgta gaaacgttga
      301 ataaaaaacg aggaaaagta tccagtgtcg gcgacatttt gaataaacat gttttttacg
      361 taaaagaatc cgcctatctt cgtgatacct tgcaacgcat tttaaaacgc gggctgaaat
      421 acgtgccggt cgttgatgaa cagaacaaag tcgtaggtat cctgactcgt gcatcattag
      481 tggatatcgt ctacgatgtg atttggggag aagatcccgc aactactgat gttgcagagt
      541 cagctactcc tgaagaatct aaggaggtct gacctatgca gcagtttttt catcagcacg
      601 gttcagaaat tctctcaaaa ggttttgaac atctttatat ttcaggactt gctttgatca
      661 ttggtatcat cattgctgta ccgcttggtg tcttactgac acgttttcca aaagctgcca
      721 cgattgtgat tggcttaacc agtgccttgc agacaatccc ttctcttgct ttattggcat
      781 tgatgatccc gctatttggc gtaggtaaat tacctgcgat tatcgcactc tttatttatt
      841 cattattgcc gattttacgt aatacgtaca ttgggatgaa aaatgtcgat tggaattatc
      901 gggatgtggc aaaaggcatg gggatgactg agttccaatc cattttttcc gttgaattgc
      961 ccattgctat gccaacgatc atggctggta ttcgtttagc tgccgtttac gtgattgcat
     1021 gggctacact tgcctcttat atcggcgctg gtggtttagg cgatttgatt tttagtggac
     1081 tgaataatta ccaaccagat ctcattttgg caggtacgat ccctgtaaca attttagcac
     1141 tattggctga ttggcttcta ggtctcttgg aacaccggct gacaccgatc gcacttagag
     1201 aggagaatga agaatgaaac gtatactaaa aatgaccatg gttcttttct ctcttcttat
     1261 acttgcgagt tgttccttcc ctggtcttgc cagcaataca gatgaagaca ccatttcgat
     1321 cacaggtgga atcacttcag aagcacagat cttagcaagt ctagttgccg gaatggttga
     1381 acattataca gataaaaata ccgcaatcat caacaatctg gctactacaa ctatcaacca
     1441 tcaagcgatg atgaacggag atgcttcaat ttcagcggct cgctacacag gaacagattt
     1501 aacgactaca ttgaaccttc ctcctgaaaa agatccgaaa aaagcgtttg ctaccgtgaa
     1561 agatgaattt gagaaaagat acggtcaaac gtggttcccg tcctatggtt ttgaaaatac
     1621 gtatgtcttt cttgttcgaa aagacaccgc acaaaaatac catctatcta aagtcagcga
     1681 tctgaaaaat gtagcggatg aattagtagc tggtgtagat acttcttgga tcaatcgtaa
     1741 aggagacggt tatgacggct tccaagaaac ttatggcttc tccttcaatt cgatattacc
     1801 tatgcagatt ggacttgttt atgacgcagt cgaagcagga aaaatggata ttgttcttgg
     1861 ctactctacg gatggacgga tcgccagtta tgatctagtc atgttggaag atgatcgtca
     1921 attcttccca ccatatgatg ctgctccagt tgtagacaac aagatattag ctgatacgcc
     1981 tcatttaaaa gaagccttaa ataagttagg tcataccatc agtacggaaa aaatgcagga
     2041 attgaactac gaagcagata ataatctagt ggaaccatca gtagtagcac aacgtttctt
     2101 acaagaaaac cactattttg aagggaagtg aagcaattgg ataaaatgaa tgtctttcaa
     2161 caatttttct attatttcca ggaaaatggc tcctatatct ttgcacaatt tatccgtcac
     2221 ttcctgattt ctatctatgg tgtcctcttt gcagcagttg tcgggattcc ggttgggatc
     2281 atgatttcta ggagacgtaa attagcaaac tgggtgattc gtttggcgaa tatcatccag
     2341 acgatccctt ctctagccat gatctccatt ttaatcattg gattaggcct gggagtcaat
     2401 gtcgtgattg ttactgtatt tttgtattcc ctcttaccga tcatcaagaa tacgtatacc
     2461 gggatgatcc aagtagacaa aaacatcctt gatgtcggca aaggcatggg gatgactgct
     2521 agacaacgac tattcatggt agagttacca ctctctgttt ctgttatcat ggcaggcata
     2581 agaaacgcgt tagttgttgc catcgggata accgcgatcg gtgcattcgt cggtgctggt
     2641 ggtcttggag atatcattat ccgaggaacc aatgcaacag agggcacatc gattatttta
     2701 gcaggtgcat tgccaactgc attaatggcg atcatcacgg actggctttt aggtattttg
     2761 gaaagacggc tagatccagc cagccgtaca tcacgctgat gttattgtaa aaaacaaaag
     2821 cttctgcgac catttgttgg tcgcaaaggc ttttttagtt ctgtcatttt taaggcaata
     2881 atccactctg attcttccct ccttatgggc aaagagttgc ttttcttagc tatttatcca
     2941 ttccgtatac tccaacttca tactgccaac gggttcatat ctgcatccac cgactaagtt
     3001 tttttcttat ccgctaaggc attttgccaa tccattttcc catcactcgt catggaattc
     3061 ataccacatg atctctaaat actcgtctgc ttgttctttg aattgggcat caattcttac
     3121 atcctttggc gtggctttca tttaagcctt ttccatcagt cctcgattgt tcgatgcctt
     3181 cagctgcatc atcaaaactg gtgactgccg tatcggtaac ttcgatcatc ttttatacaa
     3241 tcgggaactt gccatcctca tccttggcta aaaacatatc tagccattcc agcttctcgc
     3301 catgggaggt ttgcggttcc taaaaccggt acacgattct tatggactgc atccgtcgca
     3361 actagacttg gcgatacgat gatccttcac cagaagagca cccccgtaaa ccaattgatc
     3421 gatatattgc caataagaaa agacattggc gtaaaagata tcgatccctc gtgatgcatt
     3481 gccgttgata ctgctattca tggccgaaag cgccacgact ttaacttctt ccgtttgagt
     3541 gacattcatg ttcggcaatg tcgctttgga tacccgctct gctaaaggaa cgacactggt
     3601 attgtatttc gtatctgtat cttttccaaa agaccatgcc aacgaatcct ctgggaacca
     3661 ataagacgac tccggttgat tgtccattgc ttttttcaac atacttttgg ctgtttctcg
     3721 ataaacgaca tttccaattg tcttcgcctc actttggcga taatcgatgg tcgttgccac
     3781 tgccaacact aacaacgatg ctccaatttt actgattttc cttgtcacac ttcttcctcc
     3841 ttgttttaca taaacccgtc aacattccat tcctaaactc aaacaatgac ccttcaaagg
     3901 tggagatata ggaacaaatt aaagaaatca tgcaataaat ccaagaaggt tggttttaga
     3961 acaaaaaaag agtctccttt ttggggagac tctttgttaa ctatctaaaa aggttggctc
     4021 ttctcacttc actcataatg tgtccaggca gaataaattt ctacaacttt attttcctca
     4081 tcaactttgt aaaccactcg atgctgtcta ttcagcctgc gtgagtatct gccttcatgt
     4141 gtaggtctca gcttttcaaa agactgcgtg ggcatatatg gatcttcctt caatgtctga
     4201 atcacttctt caaattgttt ctttaaattc gtttgcttga tttttcttaa atccactttc
     4261 gcagagtttt tgattgcgac tgtatagtta ctcatcaaag agcttcccaa tcaatatcat
     4321 cgatattcgt aaagctactg tcgtcttttt cgcggtctcg tactttatct aaagtacctg
     4381 tttgctcaag aaaaagggtt tcttgaatcg ctctccagtc ttccagccca atcaatacag
     4441 cattgtttcc actacgatca ctaataatct cgatttcagt atgattttca tttacctctt
     4501 tcaataactg ataaaaattt ttacgagcag tgctaggatt catcgttgta ttagccattg
     4561 tctctcctcc tttttctgat ataattatag cgtacttgat taagtacgtc aaaaaaatac
     4621 aataaagcac ttaaattcag caaacttttc ctctttttta catagagaaa aagacccctt
     4681 tttagggagg atctttgtcc acgctcactt cttactcctt tacgactagc ggtagccaaa
     4741 cgtaaagtaa ttggtaacaa cgtatcatct ttagcaaagg tcgaatccaa agcctgtgag
     4801 tctatgcaac aacaccaata cacgaaggtt cctcgttgca gtgtgacttg attgatatct
     4861 tgaataacct gaggatacgc acgaaagatt tgtaacggtt attcaaaact gattttggcc
     4921 gtcaagtctt ctactgcctc aaaaatgatt gcctctttcg tctcctgtca ttcatgttca
     4981 ctatcgattt gatacttgct tagaccgttg ggtttgtgaa tcaccaatta aaaatggcac
     5041 tgagttatgg taacaaaaaa tggtcacttg acgaggctga gattcctact tatgaagaca
     5101 catggcactt aagagtcgag gtaaaggaag aagctgaaaa tataggaggc tgtacattat
     5161 ttggcaaagg attcggaaat tatgatcaag acatcaaaat caaaatgttt tacagctaaa
     5221 taggaagaat aataacattt catacgctgt tcccatcttt aatggcttat agagggcacc
     5281 tttagctgag aataagacaa aacagaccct ctagcttcaa ttaagagcta gagggtctgt
     5341 ttttgatttt aaaacttggt ttatttcttc aaatggtagc tataggtgct gacaacgata
     5401 ttttcacgcc aagacaatcg caatcttaac cgcaaacttg tttggttatg gagaatattc
     5461 tgccagcgtc tgtttggtac aaattgagga atcaacacag tagttgtata gttttgtttc
     5521 gctgcatttt tacttacgat atctacataa cggataattg gattttcaat cgagcgataa
     5581 gaagagtgga cgattgaaaa acggacatct gggaaatgct ttttaaattc tgcttcgatt
     5641 tctttttctt tttcgacatc ttcgtctagc gaaacatgca tcgcaacgac ataatcaccg
     5701 atcgaacgtg cgtaattcaa cgcaccgata tttacccgtg tcacattccc gactaataca
     5761 agaacggtat tcccgtcata atcatgtagt tttgcatcat tttctaaacg aagctgttct
     5821 gctacttttt tataatgatc atggatctta taaaaaatga acataacgat tggcataatg
     5881 atgaagaaag gccaaatgtc ccctaaccga tagacaaaca aaatcgcaat gattgcatat
     5941 gagatgaacg cacccgtaat attggcaatc gatttgctta accatctttt tccttctttt
     6001 ttccatttga cgaccatccc tgtttgagat aaagcaaatg gaatgaacac gccgatagag
     6061 tataacggaa tcaagcgttc tgttgagcca tggaaaataa acagcaatac gatcgaacct
     6121 agcgctagtg tgataatccc attggaatag cctagtcgat ccccacgatc ttgatacatg
     6181 tgaggcatga atttatcttt tgccagattg tatgcaagaa ctggaaaagc agaaaaaccg
     6241 gtgttagcag caactgctaa aatcagcgct gtagcaaatt gaaggacgta atacaaaata
     6301 ccatgtccaa agacagcttt accaatttga gacaaaacag tgacttcttt ttcaggaacg
     6361 atcccatacc aatagttgat aaatgtgatc cccacgaaga agaaacctaa gatcaatgcc
     6421 atcatcgtca atgtagcagc ggcatttttt gctcttggct tcttaaagaa tggtacagca
     6481 ttactaatcg cctccacccc agttaaagag gaagaaccag aagaaaatgc tcgtaaaatc
     6541 aaagcgatag aaacacccgg cacagccgct cctggaagtg cagtagcttg caatggcaca
     6601 gcacctgtca cgatattata taaaccaaca acgatcagta acgagatcac aaggataaat
     6661 gtgtacaccg gaaataatag gaacgatgca gattccctca gcccacgaag attcagcatc
     6721 atcagtagca aaacgattgt cacagaaata gcgacttgat gaccgtagag tgctggcacc
     6781 gctgatgtga tcgcttcagc acctgctgag acagatactg ctactgtcaa catgtagtcg
     6841 atcaataaag agccaccgga aatcaagcca gcattctttc caagattctc actgctgacg
     6901 acatatgctc ccccgccatg aggataagca tggatgattt gacgatatga tagcgttaat
     6961 gaaatcaata aaataataac aaaagcggca atgggtagcg aataccagat ggctgcagca
     7021 gacaaagcga ctaaaacgac aacgatttgt tccgtaccat atgcaataga tgataacgca
     7081 tcagacgaca ataatgccaa agcagcaaat cgggttaatt tgtgctcatc attttcagca
     7141 gattttaaag gcttacctac taacaacctt tttaagtaat ccaatttcta aactccttta
     7201 cacacaattt tacttcaagt tttatagtcg aaaatttata gtaaacaaga tgttatagta
     7261 cgctcactga ccttaaaagt caataaactt taagaaaata attggaaaaa aacagaaaaa
     7321 tatcaagcgc tttttcaaac gctttaatac agcaaaaatc taacattttt ttatgggctt
     7381 tttctttgaa ttctataata aaaggataga acttgactta gaaaatcaag ttctatcctt
     7441 tttgatatct taacttttgg aagagagatg taaggctgct ttctacccat cattcttact
     7501 actcgaagca tagcgcagtt gtcacaacct cttgataaac ggtgtttaaa agcttgcatc
     7561 tgcggtaata agctcaacca aattaaaaac ataagaagct gtttttattt ggtcgttctt
     7621 attacttgat gcagagcagc ttttttacaa cctcttggta cacggtgttc aatcagctga
     7681 ccctcggtat tagctcaaaa aaacggcaaa atatgaggaa ctatttttcc atttttttct
     7741 ctaatactca ggtcaaaaca ctgatttcac aacctctttt tttaatgaaa aatatggctc
     7801 tcatgcgccg cttctttgaa tttcgtcatt ttttcttcga tgaacggata gattgccgtt
     7861 cctacgattc caaagacaac aaacaaaccg atcatgatcc agattgcttt cgtagcattt
     7921 ggccaataaa ttcctcctgc agattcccgt aacaagttta ccgcatgagt aaatggcaag
     7981 aacggattga tcatttggaa gaatttccct gagacttgga tcggatagtt cccgcctccg
     8041 ccagagatcg acagtactaa gatgataata gcgatccctt taccgacatt atcgaataat
     8101 gcagccaaga catagacgat catcatgaac gctaaggcga tcaagacagc aaatgacacg
     8161 ctgtagaccg gattttggac atctactcct agtaagaaaa tattccctaa tgtaacgatc
     8221 aagctttgcg caatcgccat tgtcaaaaat gtcagcatac gagcaacgaa ttgttctcgt
     8281 ttcgtaaaat tgtttcggtc tttctttcct aaatagtatt ctgtcgtagc aacacttgaa
     8341 agaagaacag cgccgaccca cagacatagt gcagtataaa acggggtgct agctgaaccg
     8401 ttatttgcga ttggataaag cgcattggtt tgtagctcaa caggttgtgt aaagaagtca
     8461 ctttcttttg ttgcgtctag tttcaataat ttgatgactt cgcctagatc gacttcttgt
     8521 tcgccttttc ggatcgcgtc tgctgctttt tggataccag ctttgatatt tggccagtca
     8581 ttgttgatca agtccgcagc agcgttcaca gctgtttcga cttctggcat tttttcattt
     8641 actgttgtca atgtaccggt gatttcattt tttagtgctg gccaatcatt ttggataaaa
     8701 tcagcggcca atcctaattt ttgctgaatg atcggtaatt cattgttgta taggtctgcc
     8761 ccttcattga tgccattgac gatggtatcc atatttccat tcagcattgt attggcatca
     8821 tggatttctt gtccaattgc aggcatttct ttttgatatt tttctaaaat tgccactgca
     8881 ttcgttacag ttgctttcgt tgagctgaga agcgaatcaa agtcgatctg gtccgctttg
     8941 ctcagtgcgc cttgtgcagt cccaatcgta tcgatgactt ggtctagtag agaagtgaca
     9001 gtggaactga tttgacctgt attgatacca gcaatgatgc cattgatatt attaacaacg
     9061 gcatcaattt gatctagcaa ttcatcaata gccttcgtgt cttcattttg aacagctgtg
     9121 ttcaaagcag ataggcggtt ttgcagattg cttagcaagg gttttaattg atttagctga
     9181 tcaataattg gctgtaattt cgtatttcca gcacttgttt gcaatttagt caggaactcg
     9241 accagtttat cgattgcatt ttgttgttga gatattccgt caataaagcc gttcaataca
     9301 ttgctgatgt ttttcttttc atcatcagtc agcttaccat cttcaatagc tgttcttaca
     9361 gtatctatta acgaacctgt cgttgttgcc acttgtccaa ttgacttcaa tgtaacatct
     9421 acactgtttg tgatgcttgg tatcgcatct ttcagctgag aggcacctga ttttgtttgg
     9481 tttgctagat cacttgcctg attttctaaa tttttcacat ctggcaagat atcttgtact
     9541 tgttggatga tcgtcaagcc ttgttttgct tcatcgattc cttggttcat tgtctcttgg
     9601 atcgaagcaa aatcgccgtc gatctctgct agttgcttac cggcattttg gatctctggg
     9661 attttttctt gcaaatcaag gatgattttt gcttgatctt tcaactcagg cattttgtca
     9721 ttcaatgcaa cgactttttc acccatctca tctactttag ggatgtaatc cacgaattca
     9781 tttgctttat tcagtttttc cttgatttca ggtagttgac tttgtaattc gaggacttgt
     9841 tttgtgtagc cgtcgatcgt gtccaaattt tcatctgttg ataaaatcat atctttaact
     9901 ttattgatac ttactaggtt cgtatcgatg tcgtaaccta tctcattgaa tactttcaat
     9961 aaagtcgaac tggctgtttt gataaattca tttgtgattt gcgattggat cgaacttgct
    10021 cctttatcgg tgattttcgg tgcaatcgca ttgatttttt catttaccgt atattcgatt
    10081 tttggtttct tgatatcacc actagtaaaa ctcagcagat cttctgagaa atcctttggc
    10141 aagtaaatac ctgcgtaata ctttccggaa cggactccgt cttctaattg ttcttttgaa
    10201 tcaacgaatt gccatcctaa ttgtttattt ttatgaagcg attcgatgac ttgctcccca
    10261 atggccactt ctttaccttg aaactctgct ggcttgtctg cactgtaaac agcaattggc
    10321 agctctccag tatttccata tggatcccat aatgctttga tgttaaacca cgcatatagc
    10381 gaagggatga tcatgatcgc gatgatcaga agtgttgcaa tcgggttttt gaaaatccgt
    10441 ttccagtcaa gcaaatataa tcgaagcgta tttttgattg actgcatagt tctccccctt
    10501 cttctttttt cagctgaatt actttaccat gtatttcata cttttttcaa tcggcttttt
    10561 tcaaaaaagt cgaatttttg gacatatcac ggcaattgtc tcattgtaat ctcttacata
    10621 ttgagaaata attaaggatt acagccttta ctttatcatg aaataaaagg gaaagataat
    10681 tttatgccaa agtttttatc tattatacgt atacgcaaaa aagctaaaac attttttgtc
    10741 tttgccccta caaaaatgtt tcagcttttt tcgtttttta ttcctgtatt tcttattttt
    10801 cgaatgacag gatgattttc ccagcaggag gatgtccttc aactagctga tgtgcttgga
    10861 tgacatgctt aagtgaagca gacagattca ttgaaataaa aacatgaaag gctccttttt
    10921 ggtaggcttt gattatgcca gcaaaggctt ctgcatctag atattccttt cttggaacaa
    10981 acgattcata aaagccttcc tttttttgcc gcaaatctag atctgggagg tcatttaatg
    11041 caacatacct gccgcctggt ttcatgatct ggatgccggt ttctcctttg atacttcctt
    11101 tcgtcgcatc gattacaagg tctgcctgat cagcaaattg cagacctgga tttgttttat
    11161 cataagcagc aaatgctgaa gctcctaatt tttttacctt ttcctcattt ttactggatg
    11221 cactggttaa gattcggatt cccttttcat ggagaagctg gatcagactt gacccgaccg
    11281 cacctgatgc tcctagtatc attacagtat ctgtcggctg gatttccgtc aaatggttga
    11341 ttagattata agccgtaatt cctggcgtga ccattccggc tgcttcttcc caactcattt
    11401 tatctggaat ttttgctact tttgctgatg gcaacacgac ttcttctccg taagtcccgc
    11461 cgactgcatg gacagctact cgatcaccta catgaacagt tgtgacatct gaaccaatct
    11521 ctgtcacaat accagcgcca tcattacctg gtacataagg gaatttcaat gttcgtatct
    11581 ctttcatttc tcctaaacgc aaggcaacat cataaggatt cacactgaat gcttttattt
    11641 ctacacgaac atgtccagaa ccgacttctc tgggatgagc atcgatttct tcaaaaacat
    11701 cttgtgcttc tccgtaaccg ttaattgcaa atcttcgcat ggtcaccatc tccctttttc
    11761 tttaagttta cgtttatgtc tttattttga caaaaaaaat gtcttttcgt tttggcgcat
    11821 gattcaaaac aaaatagttg tcttttttcg cgtaacgtgt taaattattt atctaaaagc
    11881 gtaaagatta cgatttacgc taataaaaaa taattggagg aatttgttga tggctaaaaa
    11941 atcaaagatt gccaaagcaa aaaaacagca agaaacgatt gaacgctatg ctgctttacg
    12001 ccaggaatta aaagcgcaaa aagattacga aggcttgcgt aaacttcctt tagatgctcg
    12061 tccagaacga ttgaaaaatc gtgatttaat cgatggacgc cctcgcggat acatgcgtaa
    12121 attcgggatg tcccgtataa aattccgtga attagcacat aaaggtttga ttccaggagt
    12181 aaaaaaagcc agctggtaat ccaagtctgg ctgtaatgta aaggaggagg gcgcatggac
    12241 cactccttgg atcatcaaaa aagatacgtt cgcttcttct agcagaaatg ctggtactag
    12301 aagcagacgt atcttttttt acgcacagct ggtccttttt tatatgtaaa ggctgcatgg
    12361 ttacttcgct atatttattt agtaacagga gtcagtgctt cgatacccac actaattttc
    12421 aatgctcggt caacttctgc cataatgggt cgatccaaat ggcagacctt ttctttcaat
    12481 cttgatttat cgatcgttct gatctgctcc aacaggataa cggagtctct ttctattcct
    12541 gttccagtag ctttgatccc aatgtgagtc ggaagcttag gtttagccat ttttgccgtt
    12601 atggccgcaa caatgatcgt cgggctaaaa tggttaccta gattattttg aataaccaaa
    12661 actgggcgtg ttccgccttg ctccgatccc acgactggag aaagatcagc aaaataaata
    12721 tctcctcttt ttaccatagg atcctcctta ttcttgatat tctcttggta tccgctgtcc
    12781 taatccgcaa gccacttcat agtggatcgt acctaattga tctgctatat cctgcatagt
    12841 gatttctttg tctgcatttt tgccgataag cgtcactttt gttccgacag gaaattcttg
    12901 aggcaatcgg atcatcagtt gatccataca tacacgccca atcgtttcac agtagttccc
    12961 ttctaccaat agagaaaaac cctgcatctt tcgtggccag ccatctgcat aaccgatcgg
    13021 tatcgttccg atccactctg cttcaggagt gatatatgtt tctccatagc cgattccttc
    13081 acctgctggg agttttttga cttgaatcaa ttcagaaacc agctcaagtg ctggctgcaa
    13141 tggataaact tccggtagtg cgtgcccaga gggattaagt ccgtacattg ctactccata
    13201 acgaatcata ttgccgattg tttcatcatg ccataaagcc gttgcactat tgctgacatg
    13261 tacatatcga ggaagttcgg gaagtttttt cagcacttct ataaagcgtt ctttttgcag
    13321 attccaatat gtatcatctg cctgatctgc tgtagaaaaa tgggtaaata aaccttccca
    13381 ttctaataca cgactttctt tgatgaatgc agctgcctct tttacttctt caggtgtaca
    13441 aaatccgata cgacccatcc cagtgtctgc ttttagatga atcgaaagag gcgtctctag
    13501 cttacttttc tctaaaacag cagctgctgc ttgcaaccat tcccgtgtac ctgcagttac
    13561 tgataaatca tgagcaacag ctacagtcag tgcgtcgtaa ggaaccatat tcaagataag
    13621 gatgggctga gtaaatccag cttctctcaa ctcgactcct tcatctaaat ttgaaacaca
    13681 aaagcccgaa gctccacctg caactgctgc ctcagctgtt tcaatagctc catgaccgta
    13741 tccgttcgct tttactactg caaacaattc ttttccttgc ggaagtcttg caacttcatt
    13801 tgctacattt tcagttatag cttttttatg tatcactgct ttcgttgggc ggtgccaagc
    13861 gacaaccatc gtttttcctt ctttctagtc ttccaaaata atttgtgcaa aagctgtttc
    13921 atttgtatga gtaatactga cccatacatt gccttcatga ggtgaacgcg tcacaacagg
    13981 ctgaccattt tcatttttta aaatctcgac atcttgaaag gtaacttttc cgatcccagt
    14041 tccccaagct ttagagaaag cctctttgca agcgtaacgc ccgcctaaaa attctacttg
    14101 gcgatgaaaa ggcaaggact ggaatagttt catttcatca gaggtcaaga ttcgtgcaat
    14161 gaattttggt ttttcttcga tcagccgagt gatcctagga agttcgactg catcgatccc
    14221 aattcctttt atcatatgct tttctctttt caataaattt agaacactct cattctacca
    14281 aattataacc attttgccac aaataagtcc acaaataaca aaaatgaaag tttctcttaa
    14341 aaaagagaaa ctttcatttt atgtttaatc gttatttgaa cggattacaa atccgcgttt
    14401 tttatcattg tgacgtttac cgccatcttt ttggctgtta ttatttttgc tataaccgcc
    14461 ttttgatttg tttccacgat aattaccgcc gtcacgacga ttacggttgt ttccgccacc
    14521 acgtttgcca tttttattgt atcctttttt ctgcattggc aatgggcgtt ctggtgtgat
    14581 cttcactggc actgcatcag ctggatcttt tgctgtcgtt tttagcaaaa gtgcaactaa
    14641 atcttgtgca gaatattctt ctaataattt atctgctgtt tgcaggtatt tatctagacc
    14701 attttctgca agttttgttt cgatttgttc aactgcagca cctaattgac ctttgaatgc
    14761 ttctttttcg gttggtggac gtaaagtcgt catccgtttt ttcgtcaagt tttcaatcac
    14821 atgcaagtag tccatttcat ttggtgtaac gaaagtcaca gacataccgc cttttccggc
    14881 acggcctgta cgtccgatac ggtgaacgta gctttctgga tcttgaggga tatcatagtt
    14941 gtacacatga gtgacacctg aaatatctaa tccacgtgca gcaacgtctg tcgctacaag
    15001 gatatctaaa tgaccgctct taaatgaacg caatacgctc attcgttttt gttgagacaa
    15061 atcgccatgg attccttctg cacggtaacc gcgtgcttct aatccgcgtg ccaattcgtc
    15121 tacacggcgt tttgtacgtc cgaagacgat tgttaattca ggtgtttgaa catcaaacaa
    15181 gcgagtcatg atatcgaatt tttcgtattc ttttgcgcgg acatagtatt gatcgatcaa
    15241 gtcagctgtc atttctttcg ctttgatctt cacatgatgt ggatttttca tgaatttaac
    15301 gccaatattc ttgatagctg gcggcatcgt tgctgagaaa agtaatgttt gtctttgatc
    15361 aggaacttgt gaaatgattt tttcgatatc ttccaagaag cccatattca acatttcatc
    15421 tgcttcatcc aaaactaatg tttgaacggt tccaagtttc aatgtgtggc ggttaatgtg
    15481 gtcaagcata cgtcctggtg tacccacaac gatatgtgga cgatctttca agccacggat
    15541 ctgacggcca atatctgctc cgccgtaaac ggcttgtaca cgtacttttt tgtcgcgccc
    15601 taaacgatat aattcttctt gtgtttggat agctaattca cgtgttggtg cgataactaa
    15661 accttgtaat tcgtgacgat ctggatcgat tttttctaac attggtaatc caaatgcagc
    15721 tgttttccct gtacctgtct gtgcttgtcc aataacgtct tttccagcta atgctagtgg
    15781 aatcgtttct gcttggatag gcgttgcttc ttcaaaacca gcgcgttcga ctgatttcaa
    15841 caattctggt gataattcta gttctttaaa tttcaaatga atcctcctat atggttgtta
    15901 actgaggatg tagctttttt gctaccccgt cgatttgttc ggtcaaagtg tattgtttct
    15961 ttttgacagt ggccacgcac gtttttatcc attcttagcc cctgtggcac caccgaaaaa
    16021 tcactttgcg aagtttaggc attagaaaag ccaaacgggt cgcgttcagc tttatcatta
    16081 ttatgacatc tggcttcaac aagttgtttc tatggcaaaa ccagtccaat ttctcttcat
    16141 ctttcggcaa taggttattc taacatagtt tttcgttttc tgcaagttta cagattttta
    16201 tttcatttgc tgaagttgtt ctaccacttc aaataagccc atgctgttgc tgccttttag
    16261 cataatacta tctgttgctg caagattttg tttgatagca tcaatcaatt tattcttttc
    16321 tttttcaaaa tagaacacag gtagttgggg gtatttttgg ttcaattctt cttttagtgc
    16381 atgcatttgt tccccataaa ggaaaatcat ggcgaatttc tcaggatcga tatgttcact
    16441 catttgcgca tgcatattta aagactcttt ccctaattcc agcatatctg ctaacacagc
    16501 gattctgcgt ccttttgttg gcagattttt aaaagtatct aataccagtc ccatggctgt
    16561 tggatttgca ttgtagacat cgctcaaaat agctgcacca tttcctgccg ttagccattc
    16621 ggttctgttt tgagtgatag aaacatgggc gagcccttgg cgtatctcag gtatggacag
    16681 tccaaagaag cgcccgatcg tatacgcaat caaagcattc gttacattat aacttccagg
    16741 cagcgggatc gtaaatgttt ctccttctac tacaaaatcg gtttgtgctt ttccttttgc
    16801 tgtcacttcc gcatgaacat cgccatttcc aataccgaat gttgtgactg tttgtactaa
    16861 tgttgccgtt aaaggtgtca gcaacggttc atctgcgggc acaacgagta atccgtctga
    16921 tacaagtccg tcagtgattt ccattttggc tttagcgatt ccttctcgcg acccaagatt
    16981 ttctatgtgt gcttcaccga tcattgtgat tgctgcagct tttggttgag ccataagtga
    17041 aagttccgtg atttcattgg cgtgatccat gcccatttcc aaaacgatct tttctgtatc
    17101 ttggggcatg tgcaaaatcg tgtaaggaag accaatatta ttgttgtaat ttccttgcgt
    17161 cttatatgtt ttgtattttt cagacaagac agacgcggtt agatctttcg tggtggtttt
    17221 accattgctt cctgtaattg caacgacttc tgcgcctact ttttccaagt aataggttgc
    17281 caattgctgc atggctttca aaggatctgc tacaggaata actggaaaat tttttggagc
    17341 ttgttcaaca ggcaagctcc aaaatgaagc agatgctccg tttgtgatcg cttgctggat
    17401 aaattcatgt ccatctcgcg taccagcaag aggaacgaat aaacttcctt cggttatctt
    17461 ccggctgtca aattcgacat tggtaatctt tgtcagtgca gagcattcgc tgcccacggc
    17521 ttgtgcaatt tcttgtattg ttagattcat tgagatctct cctaaaaaag gttgtgaaaa
    17581 aagcgtttgg cctaaacggc gggttcgcat gactctcact tccaagtaaa tttctctatt
    17641 cgtatttaga agctagaatg aacgcggtta cgcaatcact ccagcctctt ctttatttct
    17701 ctttattcat ttttttcaaa aaaagattga cgctgatggt atcgattcat tcctaactgg
    17761 atcagttctt caatcaaatc accgtatttc aagcccatat tttcccataa gagtgggtac
    17821 atactgaact ccgtaaatcc tggcatagag tttaattcat tcaggaataa ttcattttta
    17881 tttgtcaaaa agaaatcgca ccggctcaat ccgcttccac ctaacatcgt gtaagctaac
    17941 ttcgcgtact cttgcgcttt ttgataaact tcttctggca cttcggctgg aatctgcatt
    18001 tcgattttat tattgatata ttttgcttca taatcataga atgctacgtc ttttacgact
    18061 tcaccaggca aagtcgtccg aacgtcttca tttcctaata cagcaacttc gatttcgcgc
    18121 gcttcaattc cttgttcaac gattgctcga gaatcatact gataggctgt tgctaaagca
    18181 ttttgcagct cttctcggtt ttctgctttt gtaatgccga cactagaacc catattcgcc
    18241 ggtttgacaa acatcggata aagcaaagaa ccttcacatt gatcaaatac ttttttagga
    18301 ttttctttcc attgattctt aagtactggt acataaggaa cttgcggcac accagcagct
    18361 tgtaaaatat acttggtcat gattttatcc atggcacatg cactggtcaa tacgcctgcg
    18421 ccgacataag gcatattcaa tgtctctaag aagccttgga tcgttccatc ttccccgttt
    18481 ggcccatgta aaactggaaa aacgatggct ccttcttctt tgatttcgcc cggattgatc
    18541 acttttcctg taaagccttc ctctgtctgt ccacttgggt cccatgaaag atgcaagaca
    18601 tctttgctgg caggtttttc tgttagtaat ggacctttga cccattgtcc ttcttttgta
    18661 ataaatacga gttgaacttg gtaataatta taataaatgg catttaaaac tgaaaatgcg
    18721 gaaagaatgg acacttcatg ctctgcgctg cgtccgccat atagtaaagt aatcttcaaa
    18781 agattgtcct cctgtattct aaatcgttca gtgatttact ctcatatttt agcacaaaac
    18841 aaaaataaac gaataactta tttataaaaa aacgagccag cttctaaaag aacgagcgtc
    18901 atttattttt tgtcagctag attatttgtc ccgtttttta taaaaagtta tgataaagaa
    18961 aaggagggat gatgatggcg caaacaaatc cacgcagccg cttggcagaa atcattcgag
    19021 tgttcatcaa ttacaatgta gtgccaaact ttgtacagca aaaaaatccc gaacaggtaa
    19081 aaaaagcctt tgaagaacta ggccccacct tcatcaagat aggacagatg ctttctgttc
    19141 gagaagattt gctttcttct gccttcactc aaacattcaa aacattacaa gatagtgtac
    19201 ctagcgacac attttcaacg gtcaaaaaga cgatcgaaac agaactttct ctttcattat
    19261 cagatatatt cgatgatttt tcaaaatcgc cttttgcctc tgcttctatg gggcaggctc
    19321 atcgtgccaa gctgaagaac ggtgacgcgg tagtcgttaa gatccaacac cctaacatcg
    19381 ccgaagagat ccgacttgat cttcaactat ttgaacgagc gatccctttg atcaaataca
    19441 ttcctgaaac tagcgtagtt gatctaaaag gggtactcca agaagtaaaa cgttccttga
    19501 tcaatgaaat ggacttctta aaagaaagtc aaaatggcga acaattctat caaaagaaca
    19561 atggctggaa agagatccgc agccccaaga tttatgacgc tttttgttcg aaaaaagtga
    19621 tcgtgatgga agaaatgtct ggtaaaaact tgaatcattt aatgaacgcc gaaaacaaaa
    19681 ctgaaacttt tatcactgga attcaaaaca agcagctgaa acaagaagtt gcaaagcttt
    19741 tagttgagaa ctttatgaaa caggtgtttg atgatggttt tttccatgct gatcctcatc
    19801 cagggaatct gctattccat gtactaacaa aagaagaaca gacacaagct agccgaaaaa
    19861 ctgaaacagt ccatgaaaaa gagttcggtt cctttgcttt tcgagcctcc acttctgcag
    19921 aagaccctgt tgcgccatat accatcaact acatcgattt tggtatgatg gggcatcttt
    19981 ctgcaggact taggcaaaaa ctcacacaag ccgttttagc gctgtatacg aaagatgctt
    20041 atcgaatcga aaaagcggtc cttcgacttt gtcagcaaga aggctcgttt gatgaaagtc
    20101 ggttccacca agaactgaca agttttcttg aacagtatta tgattctcct attgatgaaa
    20161 tcaacttgca agaagtattc acacatgtcg tgacgatttg tcatcaaaat aatctgcagt
    20221 tcgatcgtga tatcacgctt ttgctgaaag catttgggac attagaaggg gtgatccgcg
    20281 tcctcgatcc tgaagtttcc ctcatggaag tcgcttcgcc ttttgctcaa cattattttc
    20341 tcactcatct ggatgtagaa gatacattga aacaaagcgg attagactta ttggaaggga
    20401 tgaaggctgc gcctaagatc cctcaacagc tccaccatct attagaaatg tggacttcgg
    20461 gacaaggaaa agtcaatttg gaattgaaaa agcaagacaa attattgagc aggatcgaaa
    20521 gtatgatcaa tcggcttgtt ttcggtatga ttttagctgc attgatcgta gggtcctccc
    20581 tgcttgtcca agcagcacct gtagaaaacg cagaggtcgt ttccttatta gggatattta
    20641 cgtatgctat tgccgcattc gtcattattt ttttggcaat cgatgcattg atccaaatgt
    20701 ataagaagag gaaaaagtag aaaaaggttg tgacagaaag aatcagcttc aagaaataag
    20761 aaggggtttt acataaattg tttctcaaat ttttgtgaaa attcggctta tttttcgaag
    20821 aggctacttc tgaaacaccg agaataaaaa atgtgaaaaa gctgttctgc acccagtaat
    20881 aagaacaatc aaaaagggaa catggaacac atttatcctg tttccctgtt ccctttttga
    20941 tgtattcgag cataaataaa ataccttcgt tacctactat cttctgtact tggtaaacct
    21001 tagtcaattg ccttttttaa cgcttgacga aaagacatat gatctttctc cgtaaagggt
    21061 tttggaccct ttgtccttat gccagctttt cttaactttc cactatgata acgttgttct
    21121 agaagcgtgc cgatattcgc ttcgtcaaat tcttttccag agtgatggaa cactcgcaca
    21181 cccttcggca atacaagtga agctaaacca taatcttgcg tgatcaaaaa gtcattcttc
    21241 ttaaccatac cgacgatttt ataatccgca ctatcagctc cgcggtctac gtagacgatt
    21301 tggacatgat tagcgtattc tttggtcgta taatggtcca cactggtcac gataaccacg
    21361 tcaagaccat aggattctcc taattttatg acatcttctt ttactggaga accatctcca
    21421 tcaatgaata gcctcattct ttttcgcctt cttccataaa tgataaacag ttactaatcc
    21481 gctcagtaaa agaccaacat tgatccattt tgccaagata agcagttgta cactttctat
    21541 cggcactgat tcatggttca gcgtgatcaa taatagatgg attggctctc ccatttcttt
    21601 tgctaaaaca aacaaaagcg tcatcaataa aaactggtgg atcacactcc ctttattttg
    21661 agtagtatac ttgacaacga tccggcgatc cattggaata gctgtatcag tttgataata
    21721 ttccttattt agccagctgc ctgttactac gtgccagaaa ctaagcagaa agacacctat
    21781 cgcaaaacca tttggaatca agaggaccaa taaagaagaa ctcagtccaa gcaattgcat
    21841 agccaatgga gaccatgtta aacgtttcaa aatccatggt ccgactattt ttgctgcaat
    21901 caagcctgct gcataaggca aatacataaa aatcgaaagt ttttctaatc cgtacagtat
    21961 gccaacataa aaactgctaa ataaaaaaag gaaattccct agcattccat ttagaaaagt
    22021 aaacagattt agccagcttg gcaacttcca ttccttcttc tggtgtccta aaacaaacac
    22081 gaacaagatg aacagcagca agaaaccata aatagcaaga tcaaaaagcc tttcatcgaa
    22141 taacaatcgg gcatttctca aaagaaacaa taagccaaag aatatcaaaa ataaaacaag
    22201 ctctcgcgta gctaccagat ttcttttgat gtctttgaaa tccagttcgt aacgcggata
    22261 atgactaacc gtatggtagg ccatgacgta aaaaagtgta taaatagtaa agcttgctgc
    22321 aatctgagtc ggtgcaggca actcaatcgc ttgatacagg agaaatagcc agatagctgc
    22381 aaataagtac tttttcccat ccatattgat aaaaccttgc gtcttttcgt gaaaattgac
    22441 cgtggtatta gcaggtacaa gccatgctgc actcagccct agcaaaacac ttgaaaaata
    22501 aaataaagga aaataaaata cgcctaatat tccaagcaat gaaccagcac caccaatcag
    22561 cagagcgatc atcagcaacg tgtaactatc tagaccaaat cgtagactgt tgactaaaaa
    22621 tagtccagtc atccgaaagg cataaaacag cgtaaatggc aaaatcgtca gccaattatg
    22681 cgagtctgtt agtcccaaaa ataaaagata aggaataaaa ataaccgtgt tacttaagat
    22741 aaagggcgtt gtttgtgtaa aattacgccc aaatcgtttg agtttttcga acatgacaat
    22801 ggctccttaa acagtcttat aactaatctg ctcttcgatt ttagcattaa aggggaaata
    22861 aaccaatttt acagaatata ttcttgtaaa aaaaaataca gaaagaagca taagcttctt
    22921 tctgcatttt tacggtactt gattactcaa gcagacaagc ccttctccac aaaagtcttg
    22981 cccgacaccc ctgcatccgg caggtgataa agatagaaat caattatcct gtgcctccaa
    23041 aatcaattag gagctctgta aaccagagtc cttctcgacc cgtcgcataa atttacttta
    23101 acacagttcc tatgtttatg cgagagcttt tttcatttta taatcgacca tttgaaatcc
    23161 ttgaccgata tctgaaataa gttcttctgt aatctcaaat ccttcatgct tataaacctc
    23221 gattgcttga tgattcccct gattcactcg caaaaagatc tctctttcct ttgtttgcgc
    23281 agcaagttct tcataccagc gaaaaactga agaagtcaat ccttgaccac gtactttatt
    23341 tagcaaatat aatttactta aataaatttt tccatttatc tcttcataag cagtgtaacc
    23401 gacagtcttt tcttcgcttt ttaataaaaa gtaggacaca ccttctgtca gttctttttg
    23461 aatctgtttt tttgactgat aagttttcag catgtaatcc acttgttttt gaccaatgat
    23521 cggcacaaaa gcttccggcc atacttcttg tatgactgcc atcagctcat ccagttcatt
    23581 ttctgttact tttatttttt ccatacaccc acgtcctttt ttacattata aatgaccttg
    23641 cgcttgatgg aataaaaaga gcatgatcat gctatacaca cccaccgacc atggtttcaa
    23701 gaaaatcaca atctgcataa attccctaaa agataatttc gtcaaaccag ctactagaca
    23761 gatcaagtcg tctggcgcaa agggaagcag caaggtaaca actagtactt ttttaatatc
    23821 tttcgttttt cttgtcagca attcatcaaa tttctgatac ttttttggcg ataaaataag
    23881 ctggacaaag gctacgccat agtaacggac aagcaaaaat ccgattgctt ccccaatcac
    23941 taggccaata caactatata aaagcccaaa tccattgcca aacatcagca tgcccgctac
    24001 tgaggagatc cctcccggca aaataggaat gatcacttgg atcacttgca acagaacaaa
    24061 tatcatcact gcatacttgc caaattgctg gataaacgct tgcaaagacg tgctcgatcg
    24121 aaaaatccca tgatgataag cataaagaat caacacaaag aaaaaaaaca gaccaataat
    24181 gggcatgatc tgaagacatt tttgtaaaac tgatcctttt ttagacatct atattcccca
    24241 catctttttt catttattaa aactgcctcc tt
//
LOCUS       DACDLM010000041        24022 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.041, whole genome shotgun sequence.
ACCESSION   DACDLM010000041 DACDLM010000000
VERSION     DACDLM010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24022
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.041"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            1127..1453
                     /locus_tag="IV356_001702"
     CDS             1127..1453
                     /locus_tag="IV356_001702"
                     /inference="COORDINATES: protein motif:HMM:NF013698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAP9015390.1"
                     /translation="MFKIFRKNCCGLDVHKTWIYACIGITDANGRTVYKQARFSSFTK
                     GLNELAEWLAKYNCKDVCLESSGKFWIPVFNILEKTCFVTLAHPKYTKPQKGNKTDRK
                     DAKMDL"
     gene            1461..2369
                     /locus_tag="IV356_001703"
     CDS             1461..2369
                     /locus_tag="IV356_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAP9015391.1"
                     /translation="MCDMIKPSFIPGLEIRQLRDLMRYRTKLTNMKTSEKNRALNCLT
                     VSNLKLDDVFSDVFGKSSTSIIQYLLEHPGESFDVRPFIHARCKTPVEEIQAAVEGAI
                     SVPQAIKLRQCLNHINEIEKHREEINLEIQALAEPFSPVLELLRTIPGLDTQPITAIA
                     ILSEIGPDMSVFPTSKHFISWAGCCPRNDRSARRTKSTRISRAGQSLKPLLVQIANAL
                     LRSKEHPEFKNRYRRIKANRGHKKAIIAICKMLLTAIWNVLSKVEPYSAKGYLEPKPA
                     KEEKVLTQSQALDLLRKRGYTIIDSA"
     gene            2998..3249
                     /locus_tag="IV356_001704"
     CDS             2998..3249
                     /locus_tag="IV356_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HAP9015392.1"
                     /translation="MKSNQKSGFYTFIKAISSVLECDCIIGPYSMLIKMGFPSTESLD
                     SFINDLSKFGRTNTQIVFSTLVSLMVYQFWNVYHALLLK"
     gene            3791..3949
                     /locus_tag="IV356_001705"
     CDS             3791..3949
                     /locus_tag="IV356_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP9015393.1"
                     /translation="MNKKQACEFLGIDNNTLDKWIRVYNFPVIKIDGVVRFDVEDIKD
                     FMNTFKKN"
     gene            4021..5247
                     /locus_tag="IV356_001706"
     CDS             4021..5247
                     /locus_tag="IV356_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP9015394.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGIASEKYQKVFPTRQLAIKA
                     EREMKKKIETVLREENANSLELKGKIKFKDFYESKWLPRYELGQTTRSNRAPSNVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILCYIEFNRTTKIIQCITAPKKMALEEKRIREGNQALSSEELTDWIEAVNNDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFNKNTVRLKYALDKYQRKTHTKGWKDTV
                     IQAPEVVMTLLREWKSAQAEQLLKLKIIQTPDQYLFTYSKPSGEVNCPVHADYLNYRI
                     NAIKKRHPELAQLSPHKLRHTYATIAREGGANMNQISNALTHSDISTTKIYVNTPDVV
                     DKSVFEAFQKGLNKCD"
     gene            complement(5336..5728)
                     /gene="rpsI"
                     /locus_tag="IV356_001707"
     CDS             complement(5336..5728)
                     /gene="rpsI"
                     /locus_tag="IV356_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAP9015395.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(5744..6187)
                     /gene="rplM"
                     /locus_tag="IV356_001708"
     CDS             complement(5744..6187)
                     /gene="rplM"
                     /locus_tag="IV356_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HAP9015396.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(6706..7173)
                     /locus_tag="IV356_001709"
     CDS             complement(6706..7173)
                     /locus_tag="IV356_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HAP9015397.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(7293..8831)
                     /locus_tag="IV356_001710"
     CDS             complement(7293..8831)
                     /locus_tag="IV356_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HAP9015398.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            8911..9597
                     /locus_tag="IV356_001711"
     CDS             8911..9597
                     /locus_tag="IV356_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HAP9015399.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(9798..10325)
                     /gene="msrA"
                     /locus_tag="IV356_001712"
     CDS             complement(9798..10325)
                     /gene="msrA"
                     /locus_tag="IV356_001712"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAP9015400.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(10409..11086)
                     /gene="pgmB"
                     /locus_tag="IV356_001713"
     CDS             complement(10409..11086)
                     /gene="pgmB"
                     /locus_tag="IV356_001713"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAP9015401.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(11083..12213)
                     /locus_tag="IV356_001714"
     CDS             complement(11083..12213)
                     /locus_tag="IV356_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAP9015402.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(12213..14396)
                     /locus_tag="IV356_001715"
     CDS             complement(12213..14396)
                     /locus_tag="IV356_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAP9015403.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(14393..15418)
                     /locus_tag="IV356_001716"
     CDS             complement(14393..15418)
                     /locus_tag="IV356_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP9015404.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(15463..16290)
                     /locus_tag="IV356_001717"
     CDS             complement(15463..16290)
                     /locus_tag="IV356_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAP9015405.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(16287..17354)
                     /locus_tag="IV356_001718"
     CDS             complement(16287..17354)
                     /locus_tag="IV356_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HAP9015406.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKHGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLIGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(17380..18216)
                     /locus_tag="IV356_001719"
     CDS             complement(17380..18216)
                     /locus_tag="IV356_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP9015407.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(18213..19082)
                     /locus_tag="IV356_001720"
     CDS             complement(18213..19082)
                     /locus_tag="IV356_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP9015408.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(19152..20435)
                     /locus_tag="IV356_001721"
     CDS             complement(19152..20435)
                     /locus_tag="IV356_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAP9015409.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(20449..22134)
                     /locus_tag="IV356_001722"
     CDS             complement(20449..22134)
                     /locus_tag="IV356_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HAP9015410.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            22409..23434
                     /locus_tag="IV356_001723"
     CDS             22409..23434
                     /locus_tag="IV356_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP9015411.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
BASE COUNT         6989 a         4994 c         4308 g         7731 t
ORIGIN      
        1 ttattctttc taaaaaatat actcacttct tttcttagac ttcttttttt gattctcctc
       61 tttatggtct tgtccttttt tgccttcaaa atatttaaat aaaccccttt caaaagcatt
      121 tctaggtttt ggacaataag gaatgacttt tttcttcata taaatacctc atttaactat
      181 ttgatatcat cacattatca aaaaaaatag gttttttatt aaaactatct tgacctttcg
      241 ggagatttca ctgtgattta tttttattcc catacttttt tcgttggtca ctttcgtata
      301 cctaatctaa gcgatcatcg gcgacggtgc ttttacaacg aatggcagga caaaacaagg
      361 ggcggaaaaa cttttttgcc tatttcataa aaaacttttt cctacagcaa tcccttgttt
      421 tgtcctacca cacgttgtga acccaaagca cgccgacgaa cgcttagcta tacgaaaatg
      481 acctccaaaa acaaaaaagt gaggtgaata gaaacaaaaa gaaattgaaa tctcccaaaa
      541 tgtcgtccgc ctcggagaca acttgctgct gaaaatggtt ggttaattca tttaagtatt
      601 aaataagata aatcatcaaa ttaatcggaa aaatagcatg attggcctta tcaaaaataa
      661 actgtaaaaa cttatatttc tatgagtggt ggaacaatgc taataccaaa ttaatttatc
      721 gattacccac ctgcacaaac caaagatagc attattagga aacgaatcaa tcagcgaatc
      781 cagcattata atgaggatac taaaaataaa gttttcataa ttataaatcc gccttcctac
      841 gaaaggcacc aatgaggtga tgaaaacctt agagcgcttt ctttcttttt ttattccgtg
      901 ttaccctttc cttgcaggtc cctggtacac tacagaaccc gaggaggtga gtggcggggc
      961 tgtatagcgg caaccccgca taattatatg gtgtcggtca tccgttaagg catcaatgaa
     1021 tggcgcaaac ccgtagcccg taaacttatc tcttccgaag ttgactcgat ttcgccggat
     1081 gaccagtccc taccaaacct gtactatttt tttacaggag gttgctatgt tcaaaatctt
     1141 tcgtaaaaat tgttgtggct tggatgtcca caaaacgtgg atctatgcgt gtatcggaat
     1201 cacagatgcg aatggtcgta cagtgtataa gcaagctcgc ttctcttcct ttacaaaagg
     1261 tctcaatgaa ttagctgaat ggcttgctaa atacaactgt aaggatgtgt gtttggaatc
     1321 ttccggtaaa ttttggattc ctgtttttaa tattcttgaa aaaacttgtt ttgtcacact
     1381 ggctcatccg aagtacacca aaccccagaa aggaaataaa acagatcgca aagatgcaaa
     1441 aatggatttg tgatctcttt atgtgcgaca tgatcaaacc cagttttatt cctggtcttg
     1501 aaatccgcca gcttcgtgat ctaatgcgtt atcggacgaa actgaccaac atgaaaacaa
     1561 gtgaaaagaa tcgtgcttta aactgcttaa ccgtttctaa tctgaaacta gatgatgttt
     1621 ttagtgatgt gttcggaaaa tcatccactt ctatcatcca atacttgtta gaacatcccg
     1681 gtgaatcatt tgatgttcga ccatttatcc atgcccgttg taaaactccc gttgaagaaa
     1741 tccaagcggc agttgagggg gcgatttctg tacctcaagc gattaagctt cgccaatgcc
     1801 tcaaccatat taacgagatt gagaagcatc gagaagagat caatctagag attcaagctc
     1861 ttgcagaacc cttctcccct gttttggaac tacttcgtac cataccgggc ttagacactc
     1921 agccaataac agcgattgcg attctttcag aaataggacc ggatatgtcc gtgtttccaa
     1981 cttcgaaaca ctttatttct tgggctggat gctgtccaag aaacgatcgc agtgcccgac
     2041 gaacaaaatc aacacgtatc tctcgtgcag ggcagtcgtt gaaaccgcta cttgtacaga
     2101 ttgccaatgc tcttctcaga tccaaagaac atccagaatt taaaaatcgc tatcgtagaa
     2161 tcaaagcgaa tcgtggacac aagaaagcta tcattgctat ttgtaagatg ctcctgaccg
     2221 ctatctggaa tgtcttatca aaggtggaac cctattctgc taaaggatat ctggagccaa
     2281 aacctgcgaa agaagagaaa gttctgacgc aatcccaagc tctggacctt ttaagaaaac
     2341 gcggatatac cattatagat agtgcttaaa ccaaagttac gttgattctt cctaaataga
     2401 ctcgttgtct tccatttcaa aaattttgaa aacggtaggc ttatttagtg taccgttctt
     2461 caggtatctt caaatagatt tattttcaaa cttatttcct ttcttctttt actctcctat
     2521 agcttagcat ttaagtgggc actcgtgtca ccttgctaga tagctatgaa tgccgtaata
     2581 agcctcctag tatataggca gactgccaat tataactgat tcaatccaca ttatgataaa
     2641 atccaccttt tcgtttcata tgtgttgaaa tatcacatat gtcaaaagtg cacgagtctt
     2701 ttcattcagt gctttgtaaa tactcaaaat tattcctttt cactttaaaa aaaagataat
     2761 tagtacaaaa tcagaaatga ggaaagtatt aggatggact agaaaggagt tgttgaattt
     2821 gttgcaacag attggtcatt tatcaattaa aaattaggtg aagttttatt catcactgca
     2881 gctgctgttt cccagagaat aaaacgtcta gaagaaactg gtcagttact gtattatcaa
     2941 gcagcaattg actacgaaca agcttgatta ctaaccaaag cgtttatcca cctgttgatt
     3001 aaatcaaatc aaaaatcagg tttttatacg ttcataaaag caatctccag tgtactcgaa
     3061 tgtgactgta tcataggtcc ttattcgatg ttaatcaaaa tggggtttcc ttctaccgaa
     3121 tcattggaca gttttatcaa tgatttatca aagtttggac gaaccaacac ccaaatcgtt
     3181 ttctcgactc ttgtttcctt aatggtttat cagttctgga atgtttatca tgcgctttta
     3241 ttaaaataga aaagagcttt tttcatgcga caaagcagtg atcatttatt ggcacatgca
     3301 atctttgtgg atccattttt tgaaaatacg atatttagtt ttgacccaaa aatctttaaa
     3361 tacgtatttg ataatttatc ttaacaacca gataatttta ttcagcaccg tattatctat
     3421 attgaattct cggaatcaag ataaattttt ttccgttttt gtttcttttt taatcttctt
     3481 cttgttatta atagtgatta ggatgatatt cctatattga tctttgataa ttagatataa
     3541 tttttgaata acgttccctg ctattcgagc tagaaataca agtacgccat gacctagtta
     3601 gcgacaacta cttagagatt tcttttgttc tgggacaaca aaatgccatg acaatagcag
     3661 taaataatga tacttccgta aggctcgccg taaactgggg agaggtgaaa ttcctatgtg
     3721 cttacccaaa gcggttcaaa aattttaaac tattatttta ggagatgatt ttataaaatc
     3781 gaaagcctac ttgaataaaa aacaagcctg tgaatttcta ggaattgata ataatacttt
     3841 agataagtgg attcgtgtat ataattttcc agtaataaaa attgatggcg tagttcgctt
     3901 tgacgtagag gatatcaaag atttcatgaa tacattcaaa aaaaattgaa attttcttct
     3961 cgtcacatat actataaata gcgaaatgta ctgccttact ttttaaagga gtgaggaagt
     4021 ttgcctacaa agctttcaaa tgggaaatat aaaactaatc tgaggtatcc aaaaaaattc
     4081 agagaaatca ctggaattgc atcagagaag tatcaaaaag tatttccaac taggcaatta
     4141 gctattaagg ccgaaaggga aatgaaaaag aagattgaaa cagttttaag agaggagaat
     4201 gcaaactcac tagaattgaa aggaaaaata aaatttaaag atttttatga atcaaaatgg
     4261 cttcctagat atgaactagg tcaaactact aggtcaaaca gggctccaag taatgtaaca
     4321 attagtaata ctaaggatat attccgattg cacatccttc caatgtttgg tgaatatgca
     4381 atgaattatc tgaattcaaa tactgagata atatcagatg aattaacaaa gaaatcgaaa
     4441 gaatacgcaa atataaaaat tatcaaaggc tatgttcgct ctatgtttga tattgccgaa
     4501 atactatgtt atatcgaatt caaccgaact accaaaatta ttcaatgtat taccgcgcct
     4561 aagaaaatgg ctttagaaga aaaaaggata agggaaggga atcaagcatt atcatcagaa
     4621 gagctgactg attggataga agcagtaaac aatgacttaa ataatcactt gcttacactt
     4681 cacgattaca cacttttcat gcttacctta tatctaggtg atagaaaaag tgagacttat
     4741 gctctgcaat ggaaatatat tgattttaat aaaaatacgg ttcgtctcaa atatgcttta
     4801 gataaatatc aaagaaagac acatacaaaa ggttggaaag acaccgttat tcaggcacca
     4861 gaagttgtga tgacattatt aagagaatgg aaatcagctc aggctgaaca attgttgaaa
     4921 ctaaaaatta tacaaacacc tgaccagtac ctctttacct attccaaacc ttctggagaa
     4981 gtaaattgtc ctgttcacgc tgactactta aactatcgaa tcaatgcaat aaaaaaaagg
     5041 catcctgaat tggctcaatt atctccacac aaacttcgtc atacctatgc aactatagct
     5101 agggaaggtg gagcaaatat gaatcaaatc tctaatgctt taacgcactc ggatatttct
     5161 actacaaaaa tatacgtgaa cacacctgac gtagttgata aatctgtttt tgaagcattt
     5221 caaaaaggat tgaataagtg tgattaacat gtgttctcaa atgtgttctt attataaaaa
     5281 aagacacttt ccaaataatt gaaaagtgtc ctgaaatatt gatataaaaa gaatattaac
     5341 gttttgagaa ttgtgaagct ttacgagctt ttttaagacc tggtttttta cgttcgacca
     5401 tacgtgcgtc acgagtaagt aagccagcac gtttaagagc taaacggaag tcaggatcaa
     5461 cttctagcaa tgcacgagcg ataccatgac ggatagctcc tgattgtcca gcgtatcctc
     5521 cgccgtttac gttaacaaat acgtcatatg cgccttttgt ttcagtaaca gcgaaaggtt
     5581 gattgattac ttcacgcaag tcagcatgtg gaatgtattc ttcaacatct tttttattta
     5641 cagtaatttt gccagttcct ggtactagac gtacgcgagc aactgcgttt ttacgacggc
     5701 ctgtgccgat atattgaact tgtgccaatg aaattccctc ctattagatt aagtttgtga
     5761 tgtctaaaac ttctggttgt tgtgctgcat gtggatgttc tgctccaccg tatacgttca
     5821 attttgtaaa ttgtttgcgg cctaaagtgt ttttaggaag catacctttt acagaagttt
     5881 cgatcaaacg acgagaattt ttagcacgca attcgccagc agtgattgat ttcaatcctc
     5941 ctgggtagtt gctgtgacgg taataaattt tgtcagtcgc ttttttacct gttaatttca
     6001 ctttgtctgc attgatgacg atgacgaaat cgccagtatc caaatgaggt gtgaaagttg
     6061 gtttattttt accacgtagt acagatgcaa caactgttga aagacgtccc aatggaacat
     6121 cagttgcgtc tactacatac catttacgtt ctacttcgcc tggtttggcc atatatgttg
     6181 tacgcacgtt attttcctcc aatttaagtt ctgatgtttg acatacactt cgagtttccg
     6241 gggctctttg tggggcaaac aataccattt aacatattac ccgctaatct agtcaatgtc
     6301 aacgtttttc tgcttgattg aaaaatttat atgaaacttt acttcttttc tttcttttat
     6361 ataaaagggt cgtttcctgt caaaatgaaa aacaaaaaga ggctgtgaca aaagtcttgt
     6421 cacaacccct tattttgaat aaacggtgtt ctcctgccaa ctcctcggtc acaagtcaca
     6481 atatccataa aacataagaa gctgtttttt aaaattgttt cttgtgactc ggagctgaac
     6541 ggcaggctta caacctcttg gtaaacggtg ttcaatcagc tgaccctcgg tattagctca
     6601 aaaaacggca aaatatgagg aactattttg acgtttgttt ctctaatact caggtcaaaa
     6661 cgctgatttc acaacctctt tttcggtcaa gttcaacaac agtttttacg cgtcgatctc
     6721 tggcgctttg cccaaatgag cttggatcat ccagatacgt ttttctgtgg ctgttttgaa
     6781 ttcgataaag atatcttgtg ttggatcgtc gccttcttct ccagaaactt cgattccttt
     6841 ttggtaaaga tctgctagat aacgatagcc tgcaacaagt gtttccaaac gttctggaat
     6901 agtacgatcc cagcggccaa tttcatcagg gatttttgtg ttatctgcaa attcacgcaa
     6961 tgtagaataa ggtgaaccgt ctaatgtgat caagcgttcg gatacttcat ctaactgagc
     7021 gttcaaatca tccatgaact catccatcat tgggtgcaat gtaaggaaac ctggtcctct
     7081 catgtaccaa tgtgtttggt gaacaacaac agacatttgg cttagatctg caactaattg
     7141 atttaatact tctttggttt gttggaattt catctttctt gcctcctaac attttcttac
     7201 acttaaaata atagtagact ttcaatgaaa agtacaacaa aatcatttac ctgagaacga
     7261 ttttcagttc gcttttttat ccgtaaagcc aatcattttt cagaatcagc taattcttct
     7321 cgcagttgag caaattgctg ataagtctgt gctaaatgct tttgtgtcga aacaaataat
     7381 ggatagattt tctgatattt tttatgatca gtttcttgta ctccaacttg ctctttcaat
     7441 tctatcaatt cctgtgcttc actgatactt tggatctttc cgatgcttct ccagcctaaa
     7501 atcacagctc ctaatgcgga tgcttctgtg acagtaggga aaacaagcgg gtaacccagt
     7561 acatcagcca tcatctgacg aaaaatcgga gattgagcaa acccgcctgt agcacggatc
     7621 tctgtgagct gattttcctg gcaaactcct tttaaaatcc gataaaggtt gagacagatc
     7681 ccttctagaa tcgccttcat catttctttt tctgtatgtt gccgctgtaa accgataaaa
     7741 ctgccaaacg catctgcgtc ccaaagcggt gctcgctcac caagtaaata gggatgaaaa
     7801 atcagaccat tggcacccgc tggcacaaaa gcgatagccg aaagcagtgc atcatatgga
     7861 ttttctcctt tttctttagc agattgaacg acttcctgta aaaatgtatg ccctgcccaa
     7921 tcaaagatgc cagcaccatt gctagtcgct cctcccacta cccaatgttt ctgatccaga
     7981 acataacaaa acgtctccat ttctggatgg aactgaggct gagtagtaat aaaacgaagt
     8041 gctccgctcg ttcctacggt caaagcggcg atcgtatcac caaaagcacc taaccctaga
     8101 ttagaaagcg gcccgtctgc ccctcccaaa acaaatgata tatcatttgg caaacctagt
     8161 tctgctgctg tttttgatgg tagacctgtt acttgatagg tggaaggaaa gacttgcggc
     8221 aattgctcta ttcgaatgtt caagtagtca agcacttctt ctgcccattg gaattcatgg
     8281 atatcaaaat atccagttcc tgaagctgtt ccgtagtcgc tgatcagttc gccaaacaat
     8341 ctataaaaga tatagtcttt gataccgaca aaataagcag tttttttgaa taattcaggt
     8401 tggctgtttt gcagccactt gattttgttc aatggtgtca ttggatgaat cggcgtccca
     8461 gtctgccgat aaaattcttt gccaagcacg gtatatttca gtttttctgc ttcgtccgct
     8521 gctcggttat ctgcccaagt gatcattcga gataacggtg ttttctcttc atccaacaat
     8581 atcaggccat gcatcgcaga ggagaaggag acaaattgaa tgattgtgtc tgaaggcaac
     8641 tgtttaatta cttcttttat aacggtgcag acaccttgaa agatcaattc ctgatcttgt
     8701 tctgccatcc cttgtgtttc ttggatcaaa gggtagcgaa aataagcgga tgctgcttct
     8761 tgggcttcat ctgtgaaagc aactgctttg gtttgtgtgg ttccgatatc taatccgatt
     8821 gaaacgttca ttttttcacc tcaaatttta tgtatgtaca aaaatttagt ttaagcttgc
     8881 gtatcttggt tttgaaaagg gggagatggc gtgttacttt attttatcat tggttgctgt
     8941 atcggatcat ttttatgttt aaccgcccag cggattccgt taggtcactc tattatttat
     9001 cctagatctc attgtgtcaa atgctgtcgt tcgctttctt ggtatgaatt gattccgatt
     9061 ctctcgatca tcgtccaacg atttcgctgc cgctattgca ggtgtcggtt gcccttctac
     9121 tatttgttgg cagaagcctt atgtggtggt ctttttgcct ggttctttac tttttcttcc
     9181 gcaagaaatt tttcgacgtt catatggatg ctttcggctt tgctattttc gttgatggat
     9241 ttattttact tcatggtcca ttctcacacg ctattctgtt cttgggcaat tttatggatt
     9301 ttttggttgc aggccggcgt cttccaatgg caaagtgtgc tgttaacgtt tatcgtaggc
     9361 ggtgtgtgcc ttcgctatgg tcaatcctat ctcggagctg gcgatactct gttgatgctt
     9421 tcttggagtg gtggcttgtc tctagaagag ttgcttcaga tcttgtttct tgctagtctg
     9481 tttggaatat ccgttttttc tgtttacttt atctgtcata aaaaaaagtt ggaaaagctg
     9541 cctttcattc cttttttgag cagtgcgttg ctgattgtcc ttcatcttag gtattgaaaa
     9601 aaggttgtga caaacgactt gtcacaacct ctgatatata gtgttctctt accaaatcct
     9661 tgtgacttgg agctaggcga caggttcaca acctctccac taaatggtgt tcaatcagct
     9721 gaccctcagt attagctcaa aatgctggtt ttacaacctc tgatatacgg tgttccataa
     9781 gtagcttttt cggcttctta tttcttgacg ccccaatgtc gacgaaggaa acctgcacgt
     9841 ccagaacctt ctcgataaag attgtaatgg agcttgtttt tcttgtaata atcctgatgg
     9901 taatcttctg caggataaaa ttcgcttctt ggttcgattt ttgtcacgat tggcttatcg
     9961 aatcgcccgc tgtcttgcaa tgcttgtttt gaacgctctg caatatttcg ttcttcttca
    10021 tcattatagt agatcactgg acgataagaa tcaccgcgat cagcgaactg tcctaatgcg
    10081 tcagtcggat cggtttgctg ccaatagatt tccaccaact gatcataaga aataacttct
    10141 ggatcatatt cgatctctac tgcttctgta tgccctgttg tgcctgttgt tacttgttca
    10201 taagttggat ttggtacatg cccgccagta taaccggatg tcacagaaat gatccctggc
    10261 tgctcttcaa atggtttgac catacaccaa aagcatccgc ctgcgaaaac tgcttttttt
    10321 gtcatataaa atcccccttt tttctcatca taccttgatt tccaaaagga ggataacgtt
    10381 ttgcttgtga cagaaaaaac ggaaactatt atatacgtga tacggcttct gataaatgcc
    10441 aaaacgaacg tacttgatca aaaacggtta aatcaggaat cacatattca gcagaaggaa
    10501 gatttatgtt ttcacctatt cccaatacat gcatgttacc agccaaagct gcttgacaac
    10561 cagcttctga atcttcaatg accaagcatg catttggcgg tacattcaat tgctgtgctc
    10621 ctttgagaaa aacttctgga tcaggttttg cttttgatac ttgcgtgccg tcaataagga
    10681 catcaaaata acttgtcaaa ttcgtttttt ctaaaatgag gcgtgcattt ttgcttgctg
    10741 atcccaatcc gatcttgatg tttgtttttt tcaagtactc aagaacagct attgcaccag
    10801 gcaaaacgga tgtttcatcc attttttgaa tcgcttgaag atatagattg tttttttgct
    10861 cagcaaaggc tgatttctct ttttctgaga atttctgttc catttttcca aatgacagca
    10921 atcgctctag tgactcggtt ctggatattc ctttcagttg ctcgttttct ttctcagtga
    10981 atggaatgga cagctggtta gctaaaacca gccacgcttc gtaatgataa cgagctgtgt
    11041 ctacaagaac gccatctaaa tcgaatagtg ctgctttgat tttcatcgat tacctccttg
    11101 aaaatgaacg acttgaagta aagatgcgat gtttttagct gtgcgatgaa gattatcagt
    11161 ggcttgctgt aaagcttctt gtaaaggcac agctgcagga aggatcggaa aaacggccga
    11221 aatgccaaca tctgctgctt tttcgcttcc tttaccaaca cttccgcaaa tagctatcac
    11281 aggaacgccc tctggtactc ttctagcaat cccaactggc gcttttcctt ttagactttg
    11341 tccatctaga cgtccttcgc ctacgattac gaggtctgct tgctgtaccc gtttatcgaa
    11401 ctccagtaaa tccaatacgt agtcgatgcc agagactatt ttccctgaag caaatgctaa
    11461 cagtcctgca cccattccac caccagcact actgcccgat gcctcgatta cttgaggggc
    11521 aaatctcata taaaaatcat gcatggcttg gtcagccact gctaattcat tttctttcaa
    11581 gcctttttgt ggtccgaaaa caaaagaagc gccttctttt ccgcataaaa gattagtaac
    11641 atcagtaatg acagtgattt tggctttaat cagctcaata ggcacgttcg ttttatcaac
    11701 tgtagcaatt ttacctagat tttctcccag tgcttctact ttttgattat cttgatcgta
    11761 aaaagcataa cctagacctt ctgccatgcc gatgccgcca tcgttggtac tacttccgcc
    11821 aacgccgatg atgatgtgtc gaacaccttg ttgcaacaat tgtcgtatca gttctcctac
    11881 tcctcgcgtg gataacctaa gtggctgttg ttggtttagt gggacatctt tcaatccgac
    11941 gatttctgcc atttcaaaaa tcgcagtttg accgtctgaa gcgtactgga tttctttgtt
    12001 tttgccaaat gcattagtaa cgactgctgt ttgccgcttc aaccttaaac tgtctgctaa
    12061 tgatgaaacc gttccttctc ctccatcgcc tataggtagc agatcatatt cagcctgaac
    12121 aaaaacttct tgaaaacctg attgaatggc ttgtgctgcc tctaaggctg tcagactttc
    12181 tttgaaagaa tctggcgcaa tcagaatacg cattattttc ccctccgttc caagatcagt
    12241 tctttttcca gctggtattg gtctccattg acaaaaatag gtaatgtttc tttcgtctct
    12301 ttttttatta ctatttgttt ttttgtcaaa acaaatagca acctgtgatt tttccaaata
    12361 aaaggaaaag aaattttttc ccatgctgaa ggaagtcttg gagaaataga aagagttcca
    12421 ttcgttactg taatacctga aaaaccaaat ataactgcta gccatagtgc tcctaatgaa
    12481 gcagcatgaa ttccgtcatc tgatgaatgc ggatctggtc ctaaatcaat caggcacgct
    12541 tcttggaata aatgatacgc ccattccatt tcttggatac ggcaagcctc tatggcgtga
    12601 atcgctttac tcaacgatga gtcgtggatt gttttgtttt catagtaatg caaattctta
    12661 gaaacgattg gttgagaaaa atactcaggt aataagtata acagcatgac aagatctgct
    12721 tgcttgctga cttggagttc atttacttcg ctacgggcat aatcaagtaa aatagactgg
    12781 ctgccaggac gttctttgta agtggtcaaa tcaataactg gcttactgag atacgtgtca
    12841 tcttgcggaa tcagctgttc tttgttaggc actggcaaat ataacttatc taaaaaattt
    12901 tgacattctt tcaaaaaaag cggatcgcca gcttgatatt taacagctaa ggccacatta
    12961 taatgcgcca gatagttcgt atatgcatta ttgtcgatat attctgtgta ttcatctgga
    13021 ccaatgactc tgtgtatctc taaatgatca tcgactttta cagctctgct cagccaaaaa
    13081 gctgctgttt catgaatgag cgtttttccc tttgtttcta aaaacgattg atcctctgtt
    13141 gcttggacat actcttgaac ggcataagca aggtctgcac tgatatgatg ttctgcggca
    13201 gctgaagcaa cttcttgtct tgttccggtt ttgatattca atgcagcaaa tttgggtgtc
    13261 tcttcctgac cagtgtgtgc gctttcccat gggaaaagtg caccttgata gtgataatct
    13321 cttgcttttt gccgtgcgcc ttctaatcga tcataacggt acagcagcaa attctttgct
    13381 acttcaggaa actgatataa aaagaaaggc aggataaaaa tttccgtatc ccagaaaaca
    13441 tgccctttat aaccttcgcc agttagtccc ttcgccccta cactaacact tggatcattg
    13501 cggggagtca taatctgtaa atggtaagca gcgaagtcca tcgctaactg atcgaaagaa
    13561 gaatcgcctt ggatcgttat ccgatgctga tgccaaaaat ctgtccaata agacatcgac
    13621 tgctctaaaa tttctgtata actaacgctt ttctgggctt gggcaatact tttcttaaac
    13681 gggtctgttt gctgaagaga ggtagagagc acgatgatct tctccagcgt aaaggacgta
    13741 ttttttctga tcttttctga aaaggaagcg gtgatccggc gattttttgc ttggaataca
    13801 cctgctttat tgaatttagc tgcaatccca atatcaattt tactttctgt tgtctggtag
    13861 gatgcactga tcaaatcgtc accaaatact cgcagttctt tttcaaccaa ctgctgtgta
    13921 ccaaaattgg tttgctgtcc atcgataccc gttttcacat ctacttggca gtcttcggtc
    13981 aacggcttga tgaccacttt cagggctgcc tgatggagat tattttgatc agcaacacga
    14041 caagtaatga cttccacttt ttttccttga gcagtttcaa tgagcgcata gcgtttaagc
    14101 tctcccattt ctaaatctag tgcccgctcg tatgcaagaa ctttcatcgt ctcaagagaa
    14161 aaatgttcac cgtcgatttt tatttcccat ctgatgacat ctgggagatt cactaactcg
    14221 gctgattctg ctcctaaagg tcggttatat acaccagctg caaacattcc ccttacttga
    14281 ttccgatagt cttcctcctg gcttcctctg ataccaaaaa atccatttcc aatggtcatc
    14341 tgactcgcat acttattgat atactctaaa tcaaactgtt tttcttctac tttcataagg
    14401 taataacttc tcctgtttct gccgaacgat ataaattttc caccagattc tggatgacat
    14461 atccttgcca gccatctgca atcatctgag tctggtcacc gagcgcccga ttcacaaaat
    14521 gagccatact tagttcatgt gggtcattaa ctggcgtggt cttttgtaag gaaaccagct
    14581 ttccatctac atcttcgaat agttcgcctg gatacagatt agcacctgcc tgatcgccac
    14641 aaaaagccac attcagtttg tcttctctga tattcaaagc aaacgaagta ttcagttgga
    14701 tgatcttgcc gttttctaat tccagtgtgc caaaaattgc atcttctact gtgaatttgc
    14761 ttggatccca tttcccgaat ttccctgaat tttttttcgt accaattttt tggaagctgt
    14821 acgcccgaac gctttttact ttaggaaatc cagtaatata catcgctgta tcaagcatgt
    14881 gaatgccata atcgatcaaa ggcccgcctc cttgaagttc tttgtcgata aacgttcccc
    14941 agcctggaac accagaccga cgaagcgcat tcgcttctac gtaataaata tccccgagaa
    15001 catcaagatg attcttgatc attgttgctt cgtcagaaaa acgatgctgg aatccataag
    15061 ccaaaatctg cccgttttta tcggctgtct ctgccatctt tcttgcttga tcagctgtca
    15121 tagctggtgg tttctcgcac atcactgaag cattagcttc gagggcagcc aatacatgtt
    15181 cgaagtgaaa gcgattgggt gtacagacac tcacgatatc gggagaaatc tcattcagca
    15241 tttgtgtaac tgatgtatac gcatgagaaa atcctgtacg tcggcaaaag tcttctgctc
    15301 gctggctgac tggatcaacc acagcggcca attctaagac atctgatctt ttttgataat
    15361 aagcagcatg tactttttct gctacttgtc cagcgcctat gattgctact ttcttcattt
    15421 atttctctct cctttgctta tttacttatt gttattcttt ctctattctt tctctaaatc
    15481 atttaaatga cgcgctgttt ccagacagtt tttcaagtat tgcaatgatt cctgataaat
    15541 tttcacttca ttttctcctc gcaaacgaca ttcatatacc atataacctt catactcatt
    15601 ttgaagtagc gtttgaaaat ggcgagtaaa atcaattgcg ccagatcctg gttggtagcg
    15661 atgattatct gctaaatgga tatgacccac atactctttt tgcgtagtca atgcttttga
    15721 aatatcatct tcttcaatat tcatatgata aaaatcagcg atgatctgca catgtttcaa
    15781 ttgattagag tcaatgtaat gacgcgcatc cgctaacaaa ttgatcatat ggtcttggta
    15841 tcggttcaaa ggctccaaat aaataaccgt acctgtttct tcggctactt tatctaaata
    15901 acgaagtgat tcgctgactg ctttatagtc tccttctttg cttcggggtg aaaccatcgg
    15961 cggtaatcga taagtgaaca ttccccaagc tgctgggata acgattcctt tgcctccaac
    16021 ctcgcttagt gcacgcaaaa tctcagcaat ttgacgtaca ccattaagac gccgttcttc
    16081 gataaagtca ccgatccacc catcgtagcc gttacaagct gtcactactg ggatccctgt
    16141 ttctttgatt gcctgtttga ctgtgtcgat attttctatt aacaacttac cgtcgatttc
    16201 gtattcttca aatccacagt ctttgataaa tctaaatttt tctaaaatgt ctcttgggaa
    16261 aaatgcttga tcttgcgtac cgaatttcat tgttctcctc ctcggacttg aacgcccatt
    16321 ttgatacttt cttctgggtg ctggtctaca taacgcatgt aagcttctgc gctttctgca
    16381 aatggcacaa ctggatcaat gatttcttca caatccaagt aaccgttcat caataattcc
    16441 caacatgtgt cctcgattcg tttacggttc catcttgggt aatctgggtt tggttcacta
    16501 gatgctcgag caaagacgat ttttgcatta ttgaaatgtg cttcgcgacc aagattaaac
    16561 ccagctggaa aaggtttagc aaaggcaaca taagaaatga tcccgccata gccgatccct
    16621 attaaagaag cttgtaatgc ggcagcactg ccactcgttt caataactga atctactcca
    16681 cgtttatctg tcaattcctt tagacgaaaa ccgacatctg ctttcatagg atctagcgtg
    16741 taatcggcac cgtgtttttc tgctaattct ctacgctgcg ctatgggatc gatcccaacg
    16801 atggtagtag cacctgcttt tttagctaat tgaatcgcaa tttgcccgat agcgcctaaa
    16861 ccgaagattg ctacagcatc acctgctcga acatgtgctt cccggatacc acctaaagcg
    16921 aattgagcag gatcgtaaca tactgcattt ttccattgat ccaaccgatc aagtttacgt
    16981 agtttataat tatcaacacc gtttgtaatc agcgtttcac gaatgggtcc ataagtgcag
    17041 actaactctc ctttttgata ctctgtcacc aaactgcccg tttcttcgat cgtaccgaca
    17101 atcatatttc ctaattgaaa ttcgccaaat accacaccgc gttggcttcc ttcttctctt
    17161 ggcaagaata ggcgccattc ttctgaaaat tcttcatcga taaatggact taatcctcta
    17221 aagtcgacaa tttctgttcc tggttttgga gtagcgaaaa ttactcggat acgtacttcg
    17281 ttcttttcga tctcacggtc ttcgtaatct ttgaatccgg ctattcttgg ttctaatgca
    17341 actaattttt tcatcttttc tttcctcttt cttttctttt tatcctttta cgccgccttc
    17401 gactaaatca cctttaataa atcgttcaga taacgcatac ataatgatga ctggtaaagc
    17461 ggtcaccaat gaagcggcca tcattcgtcc ccaaatgtag tctggtgtac tgaataatgt
    17521 gttcaaaccg attggtaaag taaatttttc ggaggtcgac aggaaaatcg aagcaaataa
    17581 ataatcattc cacgaaacca taaagcaata aacgaagaca gaaatgattc cagaaatagc
    17641 caatggtata atgatccgaa taatgatctg gatccggcta agaccatcga tcattgctgc
    17701 ttcttcaata tcagtcggaa tcgtgtcaaa ataacttttt agcatgaata tcgcagtagg
    17761 aagtgtttga acgaccatcg tgataatcag tgctgtattg gtatcataca aacctagacc
    17821 ggaaatgatt ttaaataatg gaacaacgat caaaataccg gaaaacatat aaacggtgta
    17881 aaagctagca ttgattttcg agcgagcttt gaagcgtagt tttgacaaag cgtatgcccc
    17941 gctgatccca atcactactg cagttacgga ggctatcaag gagatcacta aactattttt
    18001 gaaatacatg atgaatggaa aaatctcagc attgaaaata tcctgataat gttcaaaagt
    18061 ccattctttc ggaaaaatag tttgtgtcgt tgcaattgct tcttgtgaat ccttgaatga
    18121 tgtcatcagc atgatcaaaa atggaaacaa attgacagct aatagcaaca aaatcgtcgc
    18181 gtaaaataag attttcctgc tctttttatt tttcatttca agtccacctt ctttcgtgag
    18241 agcaagacga ccgctgcaat aatgatgaac aatagaatcg atatagctgc tgcttttcca
    18301 agatcattga acgcaaaggc tgtctgatac aaataaacgc ctaagatatt gactttattc
    18361 gtcagtagat agacatctgt aaacatatag aacatccaga tagatcgtaa aacaatcaca
    18421 gttgctagta ctggtttgat tgccggcagt gtcacgatct tgaacttctg ccaagcattt
    18481 gcaccgtcca tttcagctgc ttcataaagc gttttgtcga ctgtttgcaa aatagccaaa
    18541 aatgaaataa acgcatacgg atagtatctc cagatagcaa acaaaacgac cataaagaag
    18601 ctagcaactg gctggtcgaa ccacagcggt gcttcgttga aaagctgcaa cctatctact
    18661 aacagatcat tgacgattcc ataactatta ttgaacatat atttccaagc aaaaatcaaa
    18721 gaaatagatg gcgtaacata acttaataaa atcagtgaac gcaccgtttt cctaaatctg
    18781 aacttgcggt taagcaaaat agctacggct aatcctaaag ctgtactgcc tgctacaact
    18841 aagaatgtgt aagcaactgt taaacctaaa gaacgataaa attcactatc acttaaaatt
    18901 tcaagataat tgcttaatcc gataaaaacg gcgtctgagt taggattcag cggcatatcg
    18961 aaaaaactga tctgaatatt ggaaagcatt ggaatcagca ctaaaacagc taataaaagc
    19021 atgcttggtg ctaaaagtcc catggctaat tttaagtcag aatgtttcct tggacgattc
    19081 attgaaacct ccccctgata atctgccaat agctatctac ttttttcgaa caccattggc
    19141 agaacttctt gttatttcgt atttttttgt gcgtcagcta aagcttgatc gacatcttcg
    19201 tttccgacag ttacttggtt cactgctttt ccgatcacac ctgagcttgt gatatctccc
    19261 attttcgtga aattcttttc cccgactagt ccaaagactt gtacttcatc aaaagcacta
    19321 gcaatctcag atggcagctc gccaaaagac ttgatgactt cattttcttt gtaaccatcc
    19381 agttcgacta cttgtttatt cactggttga gcaccaccag gagacatcaa gacccacttt
    19441 tccatgtttt tcggttgaga taagaaagct gtgaatgctt cagcagcctc tttttgtttc
    19501 tcgtctagac cagaagaaat cgtcaatcca gatactgtgc catagacagc ttgatctttt
    19561 tgtgttggga tagcaaaacc gatattttct gagttccccg cttcataaac agaaggcaaa
    19621 atgtaagttg aatagattgc cattggtgct gttccattca tgaaagcatc tttgatttct
    19681 gtcacatcat tagagcctgg catcgtgtat tgggataagt tttgataaaa cgacaatgct
    19741 tctctcatct tttccgtatc gatcgttacc tcgccttcat catccaaaac atttgctcca
    19801 tttgacaaag caaattgaga gaacgcttgc tcactcattg ttccttcagc agtaggcata
    19861 gcaattccat attgtttatt ctctttatct gtgaaatgtt gagcaatttt taaaatatca
    19921 tcccaatttt ctggttctga aaaaccagct tctgataatt tttctttgtc ataccaaata
    19981 ccttgaaccc agccgctaat tggtgcagca atatagcttt ttccatcttc tgaacgaaca
    20041 aggtttttgg ctccgtcata ataattatct tctccagctt cctcgataac gttttggact
    20101 gccgtctgat caatcagttc atctttatcc atcactttag caaaatcctg actgacttcc
    20161 attacttctg gtaatttacc ggaacgagct aacgtaacga tttttgtatt gaacgctgat
    20221 tcttctaccg gcacttgctt gattttgatg tctggatttt ctttttcaaa atcagcaacc
    20281 agttcattga tcacacttaa tcgttcctgt tcgacagaag agtgcatgaa ttgaatcgtt
    20341 gtctgttgtg attcgttaga gctttgactt tcaccacaag cagtaagaag aaatccagta
    20401 gctagcagac aggtagtaac aataattttt ttcatttttt tccacctctt attttattat
    20461 tttcagccac atatattcat acggctggaa tatcaacttt cgttcttgac tgcaatggat
    20521 aatttgtcca gaaaacaggt ctaggtaatc tccttttggt aaaagataac ctgctgattg
    20581 attggaaaaa ttatggataa ctaagacttt ctcttccttc gcttcgcgaa taaaactgat
    20641 aaaagaatct gctgagtcca gtaagtaaat caaactattc ggatggaagg ctttttcttt
    20701 ttttcgaata gatagcatct gggtcaattc accatatact gctgttctta atggatctgt
    20761 ctgcaactct ttctcaatat ctgctaacaa aaatttttgc cgattgattt ttcgattctc
    20821 tcctgttttt tctacgcctt tgtaatcatt tcgacttccc agcacacttt gaatataaat
    20881 tgccggcacg cctggtaacg ttaccaaaaa tgaatgagca gctaaaaagc gtttgcttct
    20941 ccattccgtc gtatctgttg gagaacttaa cgcatctaga tacgtagcgt ttatctcata
    21001 tggactggtc gttccatctg ggtttttctt gtagtttact cgggcaccct ctttcttcag
    21061 ctgttccact aattcaagga tcgttttttc cggcagaata cctcgtaccg gattcaatcc
    21121 gataccgtca tgggaggcta aaaaattaaa aaaagttgtt tttttcgatg cgaaatcgat
    21181 ggtttttaac cattctttca acttacttgt attacccgaa cgaatcgctt gaagggtcaa
    21241 aggtggtagc gaaaactgat agaccatctg tgcttcattc tcgccattcc caaaataact
    21301 gatattatct ttgtgtggca catttgtctc agtgatcaat accgttcctg gagctgcttc
    21361 atcagcgatt gcacggaata attggatgat tttatgcgtt tctggcaggt gtatacaaga
    21421 agttcctagt tctttccata aaaatcccac agcgtccaag cgaataaatg aagcgccttt
    21481 ttctaagtaa aacaaaagaa tatcgatcat tttcaataaa acttctggat ttttaaaatt
    21541 caagtctact tgatcttcgc taaaagtcgt ccatacgtgt ttttctttcc cgtttttgtc
    21601 aatgaacgtt gtaagtaacg ggctggtcct tggtctagtc acgctgcttg tatctgtatc
    21661 cagtggcaaa tcaataaaaa aatctttgta cgtatcattc aagtttaaat attcctgaaa
    21721 ccaagtactt tcggcagaca tatgattgca gacaaagtcg aacattaacc gtgtttcgct
    21781 tctcatttct tctatatctt cccatgtgcc caaacggtcg ttgattgcct gataatttac
    21841 aacggagaaa ccatcatcag atgtatatgg gaaaaatggc aagaaatgta caactctaaa
    21901 tgtatctgcc aaatactttt gataaaattt cttaaatgta cgcaaagttg gttgctgctc
    21961 ttcaaaaaat tgatccccat aagtaatcaa gaaaatatct tcttcgtccc aatgcagttt
    22021 gcctgcctgg cctttcttct gctgataaac actgactttt tgttcaatca tagaggcggt
    22081 tttctcagac aaatctgagt cgcgataaat cgcttgtaaa agttttgtat acatcggatt
    22141 cccctttctt ttttgggagc gttcccaacg atttgatcat attatggaaa acgcttactg
    22201 tcaatagcat ttttttaaat aattttgata tacacaaaaa tacaaataag aaagcttatg
    22261 tatcaataat taatagcttc ttaaaaaaat atggtctctc atgatcatgc aagctattcc
    22321 taaattttca aaatcataga caaaaaagaa tgtctattgt actatggaat tattctaaaa
    22381 cgctcccaaa aaggaggtgc atataaaatt gaaacctact atttatgaca ttgcgaaaaa
    22441 agctaatgtc tcaaaatcaa ctgtctccag agtattaaat aaccagccaa atatctctga
    22501 taaagcaaaa gcaagtgtac ttcaagcaat caaagaattg aattatgaac cgagcaaaat
    22561 tgcaagagga ctgtcaggaa atggttttga cgcgattcta gcattatctc atcgtacttc
    22621 tcatacgacc tatggcaatc cttttttttc agatgttatt caatccattt ctgccgtttc
    22681 tgaacaaaat aacttcgact tgattctaca aacggcaaaa acaccagaag aagagctaga
    22741 aaaatgcgcg aaaaagatcc aagaaaaaat gatccgagga attattattt taagctctac
    22801 gatggatgaa acacttcttt ttgaattgga tcaatacaat attcctattg tggtaatcgg
    22861 aaaagtcgga aacgactaca cgaacatcta ctcagtggac acggataatt tccaggatag
    22921 ttacgatttg gtggaaacac tgatcaagaa tggacaccgt catatcggct gtctccatgc
    22981 tccgacagaa gtttatgtat ccaatgatcg tctcaatggt taccgtcaat gcttatttga
    23041 tcaccaccta gatatccgta atgaatggat tatagacggc ggctttcgct tagaagatag
    23101 catggcagca atgaatgatt taatgaagct acgagaaaga ccaactgcga ttttttctac
    23161 cgatgcatta aaatcattga gtatttacaa agtggcagaa caatctggaa agcagatacc
    23221 tgatgatctt tcgatcgcag gattcagtga tcccttattg tcctccctat tttcgccaca
    23281 gttgactcgg atagacattc cgacaaatca gttaggaatc aaagccacag aacttttatt
    23341 ccaactaatc caccaccaat accctgaaga aaaaagaatc attctttcaa ccgagattac
    23401 tctcacagat tcgatccaac aacaagaaat gtagaacaga attataaaag aacagaaaca
    23461 ctgaggataa gtcagttact ctgttctttt ttcaatcact catccctcgt taccccctcc
    23521 cggtatttta gcgaattttt cttattttcc atctgtttta gatagctgtg gataactata
    23581 atgtttgtgt taaactattt tttccacagg gaagaaaaaa ctatttttaa ccacgttgtg
    23641 tataagtttt tatagttcgt ttttttaaac acatttaccc ttatttcaat ccatgttatt
    23701 tggggatact tatctctaaa acataaatag aataacagac atgtctactg gttttgtttt
    23761 attcgaggaa ttattcaata atagctagca aaatattaaa aataaccgct ctatcttccc
    23821 atcaatttat tttgcattca aaaaatgatc tatctttact tttgttgatt gacttctctt
    23881 ggaagatgat cgttccgata ccttaattgg atacgaaccg atgttgttaa gatcctttcc
    23941 cacttttctt ctagttagac aaattatttt agacaaacca aaaaagaggt tgtgacaata
    24001 atttgtcaca acctcttttt ta
//
LOCUS       DACDLM010000042        23883 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.042, whole genome shotgun sequence.
ACCESSION   DACDLM010000042 DACDLM010000000
VERSION     DACDLM010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23883
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.042"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(53..787)
                     /locus_tag="IV356_001724"
     CDS             complement(53..787)
                     /locus_tag="IV356_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAP9015412.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="IV356_001725"
     CDS             1114..1524
                     /locus_tag="IV356_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HAP9015413.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="IV356_001726"
     CDS             1517..2218
                     /locus_tag="IV356_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HAP9015414.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="IV356_001727"
     CDS             2218..3804
                     /locus_tag="IV356_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAP9015415.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="IV356_001728"
     CDS             3823..4044
                     /locus_tag="IV356_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HAP9015416.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="IV356_001729"
     CDS             4041..4802
                     /locus_tag="IV356_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HAP9015417.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="IV356_001730"
     CDS             5182..5691
                     /locus_tag="IV356_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAP9015418.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="IV356_001731"
     CDS             complement(5766..6305)
                     /locus_tag="IV356_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HAP9015419.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="IV356_001732"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="IV356_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HAP9015420.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7372..8169
                     /locus_tag="IV356_001733"
     CDS             7372..8169
                     /locus_tag="IV356_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-nitrite transporter"
                     /protein_id="HAP9015421.1"
                     /translation="MNPVSPLFEKIDASIEKKANLFENSFSRYAVRAVLACLFLTLGT
                     AVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAELGTSNMLYMTVGVFRQRLA
                     LSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNFMLESIAVKLAKPSATILV
                     EGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLGYEHVIANFPAFTLTYFAS
                     HGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQSKSSYVD"
     gene            8197..8832
                     /locus_tag="IV356_001734"
     CDS             8197..8832
                     /locus_tag="IV356_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HAP9015422.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="IV356_001735"
     CDS             8852..9625
                     /locus_tag="IV356_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP9015423.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="IV356_001736"
     CDS             10033..10830
                     /locus_tag="IV356_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HAP9015424.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="IV356_001737"
     CDS             10808..11221
                     /locus_tag="IV356_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015425.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13850
                     /gene="mutS"
                     /locus_tag="IV356_001738"
     CDS             11205..13850
                     /gene="mutS"
                     /locus_tag="IV356_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAP9015426.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13868..15976
                     /gene="mutL"
                     /locus_tag="IV356_001739"
     CDS             13868..15976
                     /gene="mutL"
                     /locus_tag="IV356_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HAP9015427.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15998..16558
                     /locus_tag="IV356_001740"
     CDS             15998..16558
                     /locus_tag="IV356_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HAP9015428.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16643..18631)
                     /gene="treP"
                     /locus_tag="IV356_001741"
     CDS             complement(16643..18631)
                     /gene="treP"
                     /locus_tag="IV356_001741"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HAP9015429.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18854..19567
                     /gene="treR"
                     /locus_tag="IV356_001742"
     CDS             18854..19567
                     /gene="treR"
                     /locus_tag="IV356_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HAP9015430.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19644..20090
                     /gene="msrB"
                     /locus_tag="IV356_001743"
     CDS             19644..20090
                     /gene="msrB"
                     /locus_tag="IV356_001743"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HAP9015431.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20260..20862
                     /gene="ruvA"
                     /locus_tag="IV356_001744"
     CDS             20260..20862
                     /gene="ruvA"
                     /locus_tag="IV356_001744"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HAP9015432.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20875..21876
                     /gene="ruvB"
                     /locus_tag="IV356_001745"
     CDS             20875..21876
                     /gene="ruvB"
                     /locus_tag="IV356_001745"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HAP9015433.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21905..22483
                     /locus_tag="IV356_001746"
     CDS             21905..22483
                     /locus_tag="IV356_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAP9015434.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22535..23017
                     /locus_tag="IV356_001747"
     CDS             22535..23017
                     /locus_tag="IV356_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HAP9015435.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23134..23508
                     /locus_tag="IV356_001748"
     CDS             23134..23508
                     /locus_tag="IV356_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015436.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7808 a         4289 c         5124 g         6662 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcatg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtggactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agcaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca gcacaaggat atatcgatgc cttgattgaa aaaggctata
    11461 aagtagcgat ttgcgagcag gtagaagatc caaagacgac taaagggatg gtcaagcgcg
    11521 aagtgatcca gctagtcact cctggtacag tcatggacag caaaggattg tcggcaaaag
    11581 acaacaattt tttaacagct gtagttagtc aaggaaatga atttggcttt gcttatgccg
    11641 atttaagtac gggagaattg aagacggctc ggttgcatga tgaagaagct gttttaaatg
    11701 aagcctctgc attgcagaca aaagaactcg tattaggcag tgagatcact gatacccttc
    11761 gtgaacagct aagcgggcgt ttagggctag tcttttctca acaaaatgag atggaagaaa
    11821 acgcggaatt tagctttttg acaagcgaac tagtcgatcc gctggaaaaa gaagcaaccg
    11881 gcaaactatt gacttattta tcggtgacac aaaagcggag tttagctcat atccaaaaag
    11941 cagtagaata ccaaccagat cattttttga aaatggatta ttattcaaaa ttcaacctag
    12001 aattaagcca atctattcgg actgggaaaa agcacggcac tcttctatgg ttgttagatg
    12061 aaacaaaaac agcaatgggt ggccgtttac taaaacaatg gctagaccgt ccgcttatcc
    12121 aggcaaaaca aattaaagca agacaagaaa tggtcgcttc tttgctagac agctattttg
    12181 aacgtatcga tttgcagtca gcattaacga aagtctatga tctggaacgc ctagcaggtc
    12241 gagtagcttt cggtaatgtc aatgggcgag acttgatcca gctgaaaact tctttagaac
    12301 aagtgccaat gatcagaggg ttgattgaag gaatcgatca aggtcaatgg caaagtctgc
    12361 tttcagaaat gcagccgatg gaccatctcg tccaattgat cgaccaagct atccaagatg
    12421 atccgccgtt acaaataacg gaaggaaaca tcatcaaaga tggattcaat gagcagctcg
    12481 atatgtaccg ttctgctatg agaaacggaa agaaatggtt ggcagaactt gaagcaaaag
    12541 agcgtcaaga aacaggaatc aagaacttaa aaatcggatt taaccgcgtt ttcggttatt
    12601 atatagaaat tacaaaagca aatcttggaa atgcagaact ggagaagtat gaacgaaaac
    12661 aaactttagc aaatgcagag cgtttcatca caccagaact aaaagaattg gagacacaaa
    12721 tcctcgaagc agaagaaaaa tctgttgatt tagaatatca gttgttttta gctgtgagag
    12781 aagaagtcaa aaaggctatc cagccgctac aagtacttgc aaaagcaatc agtgcagtag
    12841 atgtgctaca aagttttgca acgatcagcg aacgctatca gtatgttcgg ccagaacttg
    12901 tcagtgacaa gcatcagctt ctgatcaaag acggacgaca tcctgtagta gaaaaagtat
    12961 taggacatca ggaatatatc cctaacagcg tagaaatggc agaagacgaa atgatcttgc
    13021 tgattacagg accgaatatg tctggtaaaa gtacgtatat gcgacagttg gcattaactg
    13081 ttctgatggc gcaaatgggc tgtttcgttc cggcaaaaca agcagtttta cctatttttg
    13141 atcggatttt tacccgaatt ggtgcaagtg acgacttaat tgctggacaa agtactttta
    13201 tggtagagat gatggaagcc aatcaagccc tgcgttatgc tacgccaaac agtttgattt
    13261 tgtttgacga actagggcga ggaacagcaa cctatgacgg aatggcgttg gcccaagcaa
    13321 tcatcgaata tatccatcgt catgtacaag caaaaacact cttttctact cattatcatg
    13381 aactgacggt acttgagaaa gaacttccgc agcttaaaaa tgtccatgtt ggagccgttg
    13441 aaaaagacgg agaagttgtc ttcttgcata aaatgatgga tggacctgcg gataaaagct
    13501 acggcataca tgtggcaaag atcgcaggat tgccttccaa tctactagaa cgagcagcag
    13561 atatcctgca tacgctagaa aatggcgata acggacacca tactgttcca gctgaagtag
    13621 aagagaaaac taaaacagcc aaacaggagc aaataaaacc acctgcagaa aaagtaaatc
    13681 aagaccatat acaagaccgt gtaaaagaag aaaaccaaca gctttcttta ttcagtgaat
    13741 tatccgaaaa tgaaacagaa gtcattgaat cactgaagca aataaattta ctagaaatga
    13801 cgccaatgga tgcactaaac acattatatg aattacaaaa acaactgtag gaagaaggcg
    13861 gatatcgatg gccaaaatcc aagaattatc tgaacgttta gctaatcaga tcgctgcggg
    13921 agaagtagtg gagcgaccag cttccgttgt gaaagaatta gtggaaaatg caattgacgc
    13981 cggcagtact cagattgata tcttagttga agaagcggga ctgcggacga tccaagtgat
    14041 tgataacgga gaaggcattt tggcagacga cgtagagaat gccttcaagc ggcatgcgac
    14101 aagtaagatc cataatcgcg acgatctttt tcgcatacga acgctgggct ttcgagggga
    14161 agctttgcca agtattgcct ctgtttctga aatgactctg gaaacggcga atcaggaaga
    14221 aaaacaaggc acctatctgt cgctgaaagg cggagaagtt attgagcatc gaccagcacc
    14281 actgcgtcaa ggaacgaaga ttaccgtcag caatctgttt ttcaatacgc cagcccgctt
    14341 gaaatacgtg aaaacactgc acacagaatt agcgaacatc ggggacatcg tcaatcgact
    14401 ggcattgagt catccatcga ttgcttttcg tttagtacat gatggaaaca aaatgctggc
    14461 aactgctgga aatggcgatc tgaaacaaac aattgcggga atctacggat tatctaccgc
    14521 aaaaaaaatg ctgaaaatcg aaggaaaaga tctagatttt gagttatttg gctatgtttc
    14581 attgcctgag gtgactcgtg ccagtaggaa ttacttatcg acgatcatca atggacgttt
    14641 tatcaagaac ttttccttga ataaagcaat cgttgcaggt tatgggtcaa aattaatggt
    14701 cggtcgtttc cctattgctg tattggaaat caaaatggac ccgcttttag tagatgtaaa
    14761 tgttcatccg acgaagcagg aagtccggct gtcgaaggaa aaagaactaa cagagctaat
    14821 tagtaacgcc attcaaaaag cattgtctca agaaaatctg attccaagtg cagcggataa
    14881 tctacggttt aagaaaaaag tacctgatca gcctaaaaca gaacaaatcg aaatcgattt
    14941 gtcctacgct tttgaagaag aaaaacctaa aaagccaagt agtttgaatt ttgatcgaga
    15001 gacaggtacc tttttcgtag aagaactaaa gaacacattt gttgacagaa ttgttgataa
    15061 gtctgtggaa aatgttgaaa actattctgg tttttctgaa gaaaacacca cttatccaga
    15121 aaaaacagcg aaaacggtgg ataagtttgg tgaaaatgtt gataactttg tagaaaaaac
    15181 agtggaaaaa tctgaaaaga aagaatttcc cattgtggat aacatggaga aaacaaatga
    15241 agaacaagca gataaatccg tagaagagga tgaaaagatt tacgaggaag aattgacact
    15301 ccatcctgaa tttgatttca ctcaaggaaa cgacaaaaca ttagaacaag ccatcaagaa
    15361 attagaaacg gaaaaaccag tacaacgttt tcctcagttg gaatattttg gacagatgca
    15421 cggaacgtat ctttttgccc aaagtagcga tgggttgtac atcattgatc agcatgctgc
    15481 ccaagagcgc attaagtatg aatatttccg ggaaaaaatt ggggaagtat ctgatgatct
    15541 gcaagaattg cttgttccat ttgtgttaga ctatccaaac agtgatgctt tgaaattaaa
    15601 agagcaaaaa cacttgctag aagatgcagg gatttattta gaagaatttg gtcaaaacag
    15661 ctttattgta cgggcccatc ctacttggta tcccaatgga gaagaagaat cgattattcg
    15721 ggagatgatc gatatgctgc tgacaactgg aagtgtgagt gtaaaaaaat tccgtgaagc
    15781 aacagcaatc atgatgagtt gcaaacgatc gattaaagcc aaccattatt tgaatgaagc
    15841 acaagcacgt gtgctgctga aggatctggc acgatgcgaa aatcctttca attgtcccca
    15901 tggccgtcca gtattgattc actttaccaa ttcggatatg gaaaggatgt tcaaacgaat
    15961 ccaagacccg cattaagtca aagagaagag ggaaaacatg aagattgtat tagcatccca
    16021 atcaccaaga agaaaagagt tattggctca tatcgtttca gaattcgaga ttgaacctgc
    16081 tgatatcgat gaaacgccat ttccagacga acagcccgtc gattatgttc gtagaatggc
    16141 tgaagaaaaa gcacgaactg tctgggaaca agatgaaaaa gaagaccatt tagtgattgc
    16201 cagtgacacg actgttgttc tcaatcaaga gatcatgggt aaaccagaag atctggctga
    16261 ggctgaattc atgctgaaaa aactaagcgg ggaaacacat actgtatata cagctgttgt
    16321 tttaaaaaca aaggaacgag aagaacggat actagcagaa gcacatgtca ctttttatcc
    16381 tttgacagac gaagagatca aacgctactt ggagacgggg gattatgcgg ataaggcagg
    16441 ggcatacggc atccaaaatg ctgcgagtgt attcgtcaaa gaaatttctg gagattatta
    16501 cagtatcgta ggatttccga ttggtgctgt caatcaggca ctgaaaacat tcatttaaac
    16561 aaaaaagcgg actatctgat tttcgattga aaatccatga tagcccgttt tttttattga
    16621 aaagattact tatctactct gactaagatt ttacttcagc tttaccgact gcttcgcccg
    16681 ggcgaacaag tcctgattgg tcaagagaaa gtcctgcaac tttttcatta ttggtcaaag
    16741 caacaataat gtcagttttc ttgccagctt gttctatttc tggcaaatcc atttcagcaa
    16801 tcagggtctc tggtgtgaca aggtatcctt ctttcacgaa tacattgaaa ggaacaccct
    16861 ttagttcaac agtatctaat cccatgtgaa caagtacttc cagcccctca ttagaaagaa
    16921 taccaatggc atgttttgtt tcaaagacac tcgtcacttt accgtttact ggtgcataga
    16981 ctttgccgtt tgacggttcg acagcataac cgtcacccat cattttttgt gagaaaactg
    17041 ggtcatttac ttcagttatt tccttgatgg tccctgcagc gactgcgaat aatgtttctt
    17101 ttgttgcaac tgccgtacca gttgctgaaa caggttcgaa agactgtggc gttgctgttg
    17161 cgccatttgc tgtttgaagt tgtacatcag cagcattttc aggaacagca ggatcaatct
    17221 tattcaaaat tccctgacgt ctaaagatga tcgtcaagcc aaatggaatg atgacagcaa
    17281 tgatcattgc gatgatgaaa ggtacccatg tttctgcttg gatagctagt attcctggca
    17341 aaccgcctac tccgatcgcg ttagctcgaa cacccatcaa gttagcaaac atgccagcta
    17401 atccagagcc gaccattgca gcgacgaaag gatagacgta tttcaaattg attccgaaca
    17461 tagcaggttc agttacgcct aagtaacaag aaatcattgc tggaatcgag atttgttctt
    17521 cttttttatt cccacgatgt aagaagatga tggctaagac tgcagagcct tgggcgatat
    17581 ttgataaagc aatcatcggc cataaattcg ttgatccgaa atctgcaatc agctgcatat
    17641 cgatggcatt ggtcatatgg tggagaccag taatcactaa aggagcatac aggaatccga
    17701 atacggcact aaacaaccag ctgatagaag acgtcaatcc agtatttacg atatttgaga
    17761 tccagcttcc gactgtccag ccgataggac ctaaaataac gtgtgcagct aaaacagttg
    17821 gtaacaatga aaacaatgga acaaaaatca tcgagatcga ctgagggata tatttgcgga
    17881 agaagatttc tagatacgct aacataaacc ctgccagcat ggctggaata acttgcgctt
    17941 gataaccaat catctggact tgagcaaaac caaaatccca aaatggaata tctgctgcgg
    18001 ctgtggaagc tacactataa gcatttaata attgcggaga aactaacgta attcctaaaa
    18061 cgattcctaa tatttgtgta gtacccatct tttttgcaat actccaagtg atacctactg
    18121 gaagaaaatg gaaaattgct tcacccggta accacaaaaa ggcattgaca ccattccaaa
    18181 acttcgagtg ttcaacgatt gttccaccaa gactttcaaa ctggatacct tcaagtacat
    18241 ttctgaatcc aaggatcaat ccaccgacaa tgattgcagg aatcagtggt gtaaagattt
    18301 ctgctaaaac ggcaatagca cgttgaacgg gatgaaggtt ttgttttgca gctgcttttc
    18361 cttgttcttt ggaaacccct tcaactccag atactgcaac gaagtcgtta taaaaagtag
    18421 aaacatcgtt tcctatgatg acttggaact gtcctgcatt cgtgaacatc ccttttacgc
    18481 taggtatatc ttcgatcgct ttttcgtccg cttttcctgg atcattcagg acaaaacgca
    18541 tacgagtcgc acaatgacta actgcagcaa tattttcttt tccgccgata tcatgtaaca
    18601 gcttctcggc atctgcttga tattttgcca tatcaataaa cccctttctc ttaacttgtc
    18661 tatgcaagtt gtttcttcat ttactatact ttttttcgga gagaattgca agcgttttat
    18721 taaaaagtac gagagaaaat gatatcgttt taaaaagctt aaaataagct tttcttaaaa
    18781 ataggaacat tgaaatacaa aaagagctgt agtatagtga agaaatgatg gaagaacgag
    18841 tgagggaaaa aacatgaata agttcaatga aattttttta gatttggaac agaaaatttt
    18901 agcgaaagaa tatcctccgc attcgctttt acccagtgag aaccaattga tcaaaattta
    18961 tggtgtttca cgagaaacaa ttagaaaagc gctgaatctt ttgactacgg aaggttatat
    19021 tcaaaaaaaa caaggaaaag gttcgatcgt actggatcgg aatcgcttcg actttcctat
    19081 ttctggattg actagctata aagagctaca ggagacccaa cgtattccaa gtgaaacgat
    19141 catccatacg ttagaagaaa cagaagtgac aaaagcattg aacgagatca ctggctggga
    19201 gatcggtgcg cctgtttggc atttgatacg cgaaagaaaa atcaatggcg aagtagttat
    19261 attagacacc gattatctat taaaggaaat cgttcctatt ttaactccag cacaagcaca
    19321 aggatcgatc tatgaatatt ttgaaaatga gctttctttg acgattgctt acgcgcaaaa
    19381 ggagatcaca gtagaagaag taacggaaat catgaaaaca gcgatggatc ttcacgatga
    19441 cacttatgca gtagtagtca gaagcctcgt tcatctggaa gatacccgct gtttcgagta
    19501 ttctgagtcg gttcaccgat tagataaatt ccgtttcgtt gagtttgccc gacgccgaaa
    19561 agtgtaaata gttcaaaaga aagcaaattg ttggcatctg tccactttgg cgctatgata
    19621 ggatcacaaa gggggcattt ttaatggata aaccaataag accagaaaaa gaagaactga
    19681 aagaaaagtt atcacccatg gcttatgcag tcacacaaga aaatgcaaca gaacgaccat
    19741 ttagcgggaa atatgatgat ttttacgaaa aggggatcta tgtagatatc gtcagcggtg
    19801 aaccgttatt cagctctgca gaaaaatatg atgcaggttg tggctggcca tcattcagca
    19861 aaccaataac gaaaagacaa gtgcgcgaaa aagccgattt ttctcatggc atgcatcgaa
    19921 tagaagttcg aagcaaagaa gcagattctc atctcggaca tgtgtttacc gatggaccag
    19981 tagatcaagg tggtctacgt tactgcatca attctgcctc actgaaattc attccatatg
    20041 aaaagatgga tgaattaggt tatggggaat tcaaatcact tgtagaataa tggaaataca
    20101 caaagagcgg tacaatacgg ggatttactc gatcgtccgc tcttttttta ttcaagcgat
    20161 tgctatttga aagaaacgct ccctagactc cttttttcac aaggtgaaat gtgctacaat
    20221 aaagggaacg tatgtgtgca aaagaaagag gactagaata tgtatgaata tctgacaggt
    20281 gtggttacct ttatcaaccc ctattacata gtagtagaaa ccaatggtat cggctaccag
    20341 atcgcactag gaaatcctta ccgctacagt agcaaactaa atcaaaaaat aaaaatttat
    20401 gtccatcagg taatacgtga agatgcgcat cttctgtatg gatttgattc gctagaagaa
    20461 aagcaactgt ttttgcgatt agtaagtgtt tcaggaatcg gtccgaaaag tgcccttgca
    20521 atcatggcaa gcgaagacca ctccggtttg attcaagcag tagaatccag tgatgtcact
    20581 tatttgacga aatttccagg agtagggaaa aagacagcac aacaaatgat cttggatcta
    20641 aaaggaaaat tcggtgagct gagtatcgat acacctttta gtctatttga tgaagcaaac
    20701 acaaaagacg ctacagctct atctgaagca atggaagctc tctcggctct tggttacagt
    20761 gatcgagaaa tcaaacgtgt agaaaaacaa ttaaaagaag tagataatca gacaacggat
    20821 gagtatctac gccaagcact caagctaatg atgaaaaaat aaggaggaga ccaaatgaca
    20881 gatgaatact tgttatcacc agaatctggc gaaaatgaac tgagtttgga aaaatctctt
    20941 cgaccacagc tgctttctca atatatcgga cagagaaaag tcaaacaaga acttcagatt
    21001 tacatcgaag ctgccagaaa tcgggaagaa cctttagatc atgttctgtt gtacgggcct
    21061 cctggattag gaaaaacgac gatggccatg gtcattgcta atgagatgac cgtaaatatt
    21121 cgtacgacga gtggccctgc tatcgaacgt ccgggtgact tagtagcaat cttgaatgaa
    21181 ctggaagcag gggatgtcct gtttatcgat gagatccatc gattacctag agtggtagaa
    21241 gagatgcttt attcagctat ggaagatttc tatgtagata tcatggtagg acaagggcca
    21301 accgcacatc cggttcattt ccctcttcct ccctttactt tgattggcgc gacgacacgg
    21361 gcaggtatgc tttctgcacc tttacgagat cgatttggca tcatttctca tatggaatat
    21421 tatgacgaac aggatctgca ggagatcgtt ttacgttctt cggatatttt tcaaacagag
    21481 atcattgaag aaggggcatt ggaaattgct cgccgatcac gaggaacgcc tagaatcgct
    21541 aatcgcttgc tcaaacgggt tcgtgatttt gcgcaagtcc aaggagacgg gaaaatcgat
    21601 cgtcctatag cggatcaggc acttactttg ctacaggtcg atcaggctgg attggattat
    21661 gttgaccaga aattgttgcg aacaatgatc gagttatatg gcggcggacc agtagggtta
    21721 agtacgcttt cagtaaacat aggagaagag cgtgagacgg tagaagatat gtatgaaccg
    21781 tatctgatcc aaaaaggatt tttaaagcgt acacctagag ggcgaattgc tactgcttat
    21841 gcctatgaac attttggtta cgactatcat atatgatttt tgcttttaga ttggaggaaa
    21901 atgaatgagt gatacaacac gtacgaaaca attgatcaaa aacgtattga ttgatttgtg
    21961 ccaaacgcaa tcttttcgaa aaatcagcgt ccaaaaaatc gcaaacgaag caaaaatcaa
    22021 tcgacaaaca ttttattatc attttacaga taaatacgat ttgcttcgtt gggtctattg
    22081 tgaggatgca ttgcattatt tagatccaca atgtctttca cttgataatt gggaagagca
    22141 agcattgaaa atgctgaaag caattgctga gaagaaagaa ttttatgcaa atactgtgct
    22201 ttctgaccca gaaattttac aaaaagagtt ttctcaactg atccaaaaat catttatcaa
    22261 gatttttgaa caaatggatg aagaaagaca actttctgca agagacaaac tattttatgc
    22321 tcgttttttt tcttacggtt gcagtggtgt attagtcaat tggatcacga atgaatatga
    22381 agaaacaccg atggaaatcg ctatgcagct tttccgttta gccaaggata cggaattata
    22441 ttcttatcgt ctttatgcaa aagaagagtt ggaagaacag taatagaaaa attttttgtt
    22501 ggaaaagcaa taatcgctaa aaggagatgg ggaaatgaca aaaattttat ttgtttgttt
    22561 gggaaatatt tgccgttcac cgatggcaga aggcttgctg agaaaacgaa tagcattaga
    22621 aggaagggaa gcagaatttt ttgtggattc tgctgctaca agcacgtatg aagttggaaa
    22681 gacaccgcac cctggaacga aaaaaatatt aaaccaagaa aaagtagata tgacgaatat
    22741 ggttgctcgg caaatcacac cccacgattt tgaaactttt gattggatca ttggcatgga
    22801 tcaagaaaat gtagaagaac tgaaacgaag agcaccacgc tcagcgcagg ggaaaatcca
    22861 tttgttttta agtagcattc ctggaaaaga aaaagaaaat gttcccgacc catactatac
    22921 caataacttt gatgagacat atcacttgat cacagaaggc ctgaatcatt ggtggaatat
    22981 ttggattgat gaaaataaaa taacaaataa tttgtaaagt taacgctttc tttttaaggc
    23041 gatgttagag catttccttg tttttttgta aaatgttagg taaaataaaa ttaattaagt
    23101 aacactttct tagctaaagg aggagtgcat tcgatgaacg aagagacagt atcgccaatg
    23161 aagaagctta cgaagttagt tactcatact tcgtatcaac tttttgattc ttttgtaaat
    23221 gacactgaag aacatgctaa gaatgtacga ttgcaaggaa agtttattct tgagctgcaa
    23281 aaagctgcta ctgaacatag tctagttatc ttacaagtaa gagcaaatcg tttgagtagc
    23341 aagtatgaaa cgatctcagg ctgggtggcg acaaaaacgg tcgaaaaaga ccgagtgatg
    23401 atccgcctac aaaacgaaga gcagcagatc cggatggttc ctgtagaaca aattgaaaaa
    23461 ataacaatcc tttcaccagc aggggaacag gaacggttat caaaataatt tataccagat
    23521 agaaaagcac gtatgagctt gtaccatcaa tcattactaa tcaaaaataa ccgaatgctt
    23581 taagctgata tcagtaaaac ggaacgtttt aggatgagta tcatagcatg acagcattcg
    23641 gttgattagt tgaatcgatt ggatggtaca agtttttttg ataaaaaaag gtcctgctag
    23701 ccggggagct agcaggataa ggagttaaaa atgaaaaagt gttgttaggg ttgtttgttg
    23761 gtatgcttat ataatagtca ttagttgtga atattttgtg acgaaagttt tcgaaagttg
    23821 ttaagttttt gagagtataa aatattttgt gtaaatgaaa aaatccatac aaaaaaggaa
    23881 gtc
//
LOCUS       DACDLM010000043        23572 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.043, whole genome shotgun sequence.
ACCESSION   DACDLM010000043 DACDLM010000000
VERSION     DACDLM010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23572
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.043"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(460..1089)
                     /gene="udk"
                     /locus_tag="IV356_001749"
     CDS             complement(460..1089)
                     /gene="udk"
                     /locus_tag="IV356_001749"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HAP9015437.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1173..1868)
                     /locus_tag="IV356_001750"
     CDS             complement(1173..1868)
                     /locus_tag="IV356_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="noncanonical pyrimidine nucleotidase, YjjG
                     family"
                     /protein_id="HAP9015438.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1881..2597)
                     /locus_tag="IV356_001751"
     CDS             complement(1881..2597)
                     /locus_tag="IV356_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HAP9015439.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2927..3532
                     /locus_tag="IV356_001752"
     CDS             2927..3532
                     /locus_tag="IV356_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HAP9015440.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3857..4180
                     /locus_tag="IV356_001753"
     CDS             3857..4180
                     /locus_tag="IV356_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAP9015441.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4362..5732
                     /locus_tag="IV356_001754"
     CDS             4362..5732
                     /locus_tag="IV356_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HAP9015442.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5862..7163)
                     /locus_tag="IV356_001755"
     CDS             complement(5862..7163)
                     /locus_tag="IV356_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAP9015443.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7393..9384)
                     /locus_tag="IV356_001756"
     CDS             complement(7393..9384)
                     /locus_tag="IV356_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HAP9015444.1"
                     /translation="MATTHNTKKISMAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9528..9794)
                     /locus_tag="IV356_001757"
     CDS             complement(9528..9794)
                     /locus_tag="IV356_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAP9015445.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10304..12430)
                     /gene="pnp"
                     /locus_tag="IV356_001758"
     CDS             complement(10304..12430)
                     /gene="pnp"
                     /locus_tag="IV356_001758"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HAP9015446.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12618..12887)
                     /gene="rpsO"
                     /locus_tag="IV356_001759"
     CDS             complement(12618..12887)
                     /gene="rpsO"
                     /locus_tag="IV356_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HAP9015447.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13138..13701
                     /locus_tag="IV356_001760"
     CDS             13138..13701
                     /locus_tag="IV356_001760"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAP9015448.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13954..14475)
                     /locus_tag="IV356_001761"
     CDS             complement(13954..14475)
                     /locus_tag="IV356_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HAP9015449.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14478..15320)
                     /locus_tag="IV356_001762"
     CDS             complement(14478..15320)
                     /locus_tag="IV356_001762"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HAP9015450.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15313..16038)
                     /locus_tag="IV356_001763"
     CDS             complement(15313..16038)
                     /locus_tag="IV356_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HAP9015451.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16214..16510
                     /locus_tag="IV356_001764"
     CDS             16214..16510
                     /locus_tag="IV356_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015452.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17078..18670
                     /locus_tag="IV356_001765"
     CDS             17078..18670
                     /locus_tag="IV356_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750719.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP9015453.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18683..19423
                     /locus_tag="IV356_001766"
     CDS             18683..19423
                     /locus_tag="IV356_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAP9015454.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            19591..20940
                     /locus_tag="IV356_001767"
     CDS             19591..20940
                     /locus_tag="IV356_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP9015455.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(21068..21658)
                     /locus_tag="IV356_001768"
     CDS             complement(21068..21658)
                     /locus_tag="IV356_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAP9015456.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVIVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            21805..23157
                     /gene="brnQ"
                     /locus_tag="IV356_001769"
     CDS             21805..23157
                     /gene="brnQ"
                     /locus_tag="IV356_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAP9015457.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         6751 a         4746 c         4490 g         7585 t
ORIGIN      
        1 agggggtgcg acaaaagagc ttcttcaaaa aaataagtcg aaatctcaca caaattcgag
       61 aaataatttt cgtaagtttc ttcttattta ttgcatctga ccacttctgt tacaacctct
      121 cgttaaacgg tgttcaaaag cttgcatcta cgataataag cccaacccaa cgaaaaacgt
      181 gaggagctgt tttatttgga tgctcttatc gcttgatgca aagacagctt ttttacaacc
      241 tctacttcac ggtgctcaat cagctgacct tcggtattag ctcaaaaaac ggtaaaatat
      301 aaacagctat tttccgtttc ttctttttaa tacttaggtc aagatgctgt tttcacaacc
      361 tcttgttata aataaaaaaa cagttggctg gtgactgttc aaaaagcaga atccttgctt
      421 ttcaaacggt cgcagtccgt tcaactgttt cgctgcgcac tatttatggt ttaagaaact
      481 agctactttt gttgtaatca aatcaatagc aacgtggttt tctccgcctt ctggaacaat
      541 gatatccgca tagcgcttcg ttggttcgat aaattgatga tacatcggtt taacaactgt
      601 caaatattgt tcgatcacgg agtccaatgt gcgtccccgt tcttccatat cccgtttgat
      661 acgacgaatg atacgaatgt catcatctgt atctacgtat actttgatat ccatcaagtc
      721 acgcagacgt tcgtcttcta aaatcaggat tccttctaga atgatcactt cttttggttc
      781 ctgaatgatc gttgcctgac ttcttgtatg cgctacatag tcatacacgg gtttttcaat
      841 ggctttatag ttcagtaagt cgcctacatg ctgaatcagc agatcattat caaaggcaaa
      901 tgggtgatcg taatttgtgt tcaatcgttc ttcaaaactc aaatggctct gatccttgta
      961 ataagaatct tgttcaagca tcatgatgga atggtccggg aagttgttga aaatcgcacg
     1021 gctgacactt gtctttccgc ttccggatcc acccgtcaca ccaatgataa ttggcttgct
     1081 ttttgtcatt gactaaaacc tctttcgtat ccgttttttc attctaatct attatagcga
     1141 aaaaacacga aaatgctata tttttctgaa aattaatcct tttcaatttc caataatgaa
     1201 taaagttcct ctaatgaatc gattcgataa gtaggctgga tttcttcgat ttctggtaat
     1261 ttatttctat tgaaccaaat cgtatcgatc cctgccatat ttcctccttt gatatcagaa
     1321 gtcaaagaat caccaatgat cacagtttgc tttttatcaa aattaggaat gtgggaaaag
     1381 acatgatcaa aaaattcttt catcggcttt tgcgctccga cagcttctga gacaaagata
     1441 tccttgaagt aatcaagcat tcctgcatct gttaatcgcc gatgttgcgt gtgcgacaca
     1501 ccgttcgtca caatataaag atcagcatgc ggatggacct ttttcaggat ttctagactt
     1561 cctggaacaa gatcatgacc ttggttcaag tagtggcggt agcgtttttc catttgatca
     1621 ctatctactg ttttcccaaa ttgctggaaa agtaacccaa aacgactgcc tattatttct
     1681 tctcgtgata gtctgccttt ttcaaactcc tgccataaat gatgattcaa agccttatag
     1741 ctggtttcga tttctggtgt caatgtgatt ccttgttctg caaacaaagc acttaaagca
     1801 ttggcttcag ttaattgaaa atctaacaat gtatcatcta catcgaacaa taaagtttta
     1861 tatttcatct ttttgacctc ctatttaaaa taaatactta actttttcat ctctgctaat
     1921 gtcaacgatc gatactcgcc tactcctagc tgttcatcta attccaatgg tcccatgctt
     1981 agccgtttca atgcggtcac tttctttcct tgggctaaga acatcttttt gacttgatgg
     2041 aattttcctt cttggatcgt caataaaacc gtactttggt gcttgtctgc tttgagtatt
     2101 tttaaatcag ccggcttaca ttgataccca tcagcgaata cgattccatt ttcaaatgct
     2161 gttacgtctg ccggtgtcac cctttcgttc acaactactt gataagtctt tgaaaccttt
     2221 ttttctggaa gtagcatttc atatcccaat tgtccattcg aagtgatcag caatagtcct
     2281 gttgtatctc tatctagtct tcccactgga tataatggtt ggaaacgatc ggcacttgca
     2341 atcagatcga ttactgtcgt cttttctgga tctgatacag ctgtaacagc tttttcaggt
     2401 ttattgagaa gataatagga ctcatttgtt tctaagtgtt cacctgctac ttcgatttga
     2461 tgcagtaaac tatctacatt tcgattttgt cgaaattcga ctgtgccatc tatcatcact
     2521 tgcttcaaag caaacagccg cttcatttcc ttgcgtgtcg tttctaattt ttcttctatt
     2581 aatttatcta aacgcatgct gtttcctttc ttattactac taattaatta taccttgaat
     2641 attcttgctt gcaaatacat catcatagtt attccttgac ttaattaaca gttcacgtta
     2701 cggttaaata gtaaagtgaa ttggatttct catacacagc gtaatgacct ggtggagaaa
     2761 agttgaatcc tgactttcta aggggagatg cgcgcatctc tccttttgcg cttttttaag
     2821 cgccctgcct tcgatgatgt gcacgagatt agcctttaga attcacttaa ataaaatctg
     2881 tccgttacca aagcagacag tcacatttta aggaggaatt ttggttatgt cagtatcatt
     2941 agaagtaagt aaaagagaag tacgtccccg ttcattaaga aacaaacttc gtcacgaagg
     3001 gaaagttcca gctgttgttt atgggtataa agtagaaagt acccctatct cattcgatgg
     3061 tttgacacta agcaaattgt tgcgtgaaca tggagcgaac acagtcatca cgatggacat
     3121 cgatggacaa aaagtcaata cattggttca caagatccaa acgaacactt ttaccaatca
     3181 tttcgaacat gcagaatttc tatctgtaaa catgtcggaa gaaacagaag tcgaaacaga
     3241 agtcgttctt gttggcgaat cagtgggtgc taaatctggt ggagtgttag ctcaaaactt
     3301 gtatacagta gtcgtatctg ctacaccaga caaattgcct gaacgaattg aagttgacgt
     3361 gacaaacttg gaattaggtg attctattac agtagccgat cttccaaaaa acgacgatta
     3421 caaattcgtg accgacagtg aagagcaaat cgctgctgta gtcgctcaaa gtgaagaaga
     3481 aagcacaggt gaaggtggcg aaccagaagt gatcggttca acagaagaat aatactgaaa
     3541 caatcaggtg gtgttagaag cggcgggtca gcagctttta acacgccttt tttatttcta
     3601 atcgtttatt ttcatatggg gcttccactt ttgtaaatgg ctttacaaac gaaaaatcct
     3661 aatttaccaa gcttttcctc gcatactttt atcgtacctt tataaaaatt tatactttga
     3721 aaaaaagtat tcaattattg ttgcattttt cctgattctt tattagaatg aaccctcgtt
     3781 gaagtaagta tttctagttt atcctaggat taattataaa aataaaacat tcgttgattc
     3841 gaaggaggtt aaacagatgt ttgaaagttt tgatagcagc cgcaaccgtt acgcttcagt
     3901 tggtgtcgta tcaagtttgc cagatgaatt gattgacagt atatggttta ttattgacct
     3961 agatcttaag ggagtcattc cattagaaaa tatattaacc tttgatttga tcgaaaatcg
     4021 tggaaaagtg acgatgcatt tttctcaagc aggaagcaat gtggaaatgg atattgattt
     4081 gccgtttgcc tattcgaacc aatttcctgc tcaagtatac gcctatgatg acggtacgag
     4141 agaaacgatc cttttaccaa gtgagattag acaatattaa ggtgatagat aaacgtggat
     4201 gtcccttatt ttacagacca ggccaagttg ttgattcttt gactcaattc ttggcttctt
     4261 tttatggagt ttcataaatt atcattgatt tctaattggt attctcagga taaacgctat
     4321 atactactaa ctaaatttta aagatataag gagtttaaaa gatgcgcgat ttaacaaaag
     4381 gaagccccgc taaactgatt ttgatgttca ctgttccttt actgatcgga aatgtttttc
     4441 agcagttcta caatatgatc gatatgatca tcgtgggtca gacgctaggt aaaaatgcgc
     4501 tggcagcggt tggtgcaact ggaagcctga catttttgat cattggcttt gcccaaggtt
     4561 taacagctgg tttagccatt attaccgcac aacgttacgg tgcaaaagat tatcggggtc
     4621 tgaagaaaag ttttgctgct agtgttgtca ttagtcttgt cgtcactgtg attttaactg
     4681 tcctaagtct cctgtttatt cgtccgatgc ttcaattgat gcaaactcct cctgaaatac
     4741 ttgatcaagc acaaacattt atttcaatta ttttattagg gatctttgca tcagtcagtt
     4801 tcaatttgct ttctaatgtc attcgcgcac ttggtgacag ccgcacacca ctattctttc
     4861 tgatcattgc ggtcatcatc aacgtcgtac ttgatttgat ctttattatc tattttggca
     4921 tgggtgtgga aggtgcagct attgctacag taatcgcaca agtttcttcc agcgtactgt
     4981 gtctagtgta tatcaagaaa aaaatgcctt tgttacagtt acgcaaaaaa gatttcaaat
     5041 ttgaaaaaga agagtttgct gtacacctaa atgctgcttt gccaatggcg tttcaatctt
     5101 cgatcatcgc tgttggtgct atcgtgttac aagcagcact aaatagtcta gggacagatg
     5161 tcgtagctgc tcaagccgct gctggtcgta tcgaccaatt tgcaaatcag ccgatgatgt
     5221 catttggtat tgcaatggca actttcactg cacaaaacta tggtgcgaaa gaatatggcc
     5281 gaatcttgca aggggtacgt caaactttac tgatgagtgt cggatttagt ctcttagcag
     5341 gtgctatcgt cattttcttc ggtcatttct ttgttcaatt gtttgttagc ccatcagaaa
     5401 cacgtgtatt tgaattagca caaacctact tcaatatcaa tgggtctctt tactggatct
     5461 tagcagtcct gttcatttta cgctacacac ttcaagggct tggacaaagc aagatcccta
     5521 cgatcgccgg tatgatggaa ttgcttatgc gttcttttgc agctatcgtt cttacaggaa
     5581 tgtggggata cccaggagca gcagcagctt ctcctttagc ttggatcggt tctgttgccg
     5641 tgttgcttta ctcttatatg cgttcgatga aacaattgaa acacatgggt gaagaggaac
     5701 atttcacatt agaacatgca gaagcaagat agccttgatt aaaagaaatc gttgcggcta
     5761 aaaatgaaaa cttttattga aaatatcttc ttcgtttacc gaaaacaggt tttttagata
     5821 acaaaaaggc tgtgacaaaa aatgtcacag ccttttttct tttattctat ttttctttcc
     5881 gtggactcta ctttgaaata atcgatatgt gcatgctggt attctaatac cgtgaaacgg
     5941 aatgatgcaa tctcaatgat tgttcctgct tttatttctt tatatcggct agaagcaaag
     6001 cccgcaagtg tagtaaaatt cgtttcttca aactctggaa tctctacatg aaaataacgc
     6061 tggaaatcat ctaatgttag tttgccggag atgatataag agccatctga ctgttccgct
     6121 atcaatgctt cgtccaaatc tgtctcatct cggatttccc cgacgatttc ttctaaaata
     6181 tcttcaatcg tcactaagcc gcttgtccct ccgtattcat cttttaagat agcaatatgc
     6241 tttccctttt ttcgcatgat cgtcaataat ttttttatag ggatcgtttc agttgttacg
     6301 atcggctctt caatcaactg ttctactgtc agctggtcat ctttataaga ttgcttgatc
     6361 aaatctggca aggtgacata acctaaaaca ttgtcttttg attctaagat aaccggatag
     6421 cgagtatgtc cttgttcaat cgaagctttt atcgcttctt tgacggtttc tgaagcttcg
     6481 aatacttgca tggacgtacg gtctacttgt atatcttttg ccaaggtatc atcaaattca
     6541 aacacgtttt ccaaataatg atattcttct ttggtcaact ctcctttttc ataagaattc
     6601 aatgcgacta atgtcagctc ttcttgagac aatgtctctt ctccttcaga tacgagacgc
     6661 acacctaata gcttccctag ccctgcagct gaatgattca atacccaaat aaaaggaaac
     6721 attactttat aaaaataatg aagtggttta actacgaaca agacgacctt ctccgtattg
     6781 acgatactat agctcttagg aagcagttcg ccaataacca catcgatata cgtaactaaa
     6841 ataaatccca gcgccacaga gattgtactg ctaatagccg aactaaaagg tagtttaccg
     6901 atcactggtt ctagtaaagc cgcgacagat ccttcaccga cccacccgat gatcaaaccg
     6961 gttagcgtaa ttcctaattg actagctgat aaatagttat ctaaatggtg tgtaacatga
     7021 agagctagct tggcgttctt tacattttcc ttttctagtt gttccaatct tgatcgtctg
     7081 attttcacta aagcaaattc acttgctaca aaaaatgaag taattgcaat catcaaaaat
     7141 aaaataatga aattgataac catattctcc cgcctttctc tttttctatt gtaccctttt
     7201 tctacaaaaa gattgaaaat aatgcgtatt catatttagg aataaaaaag gagatgcggc
     7261 atttttcagc cacatctcct tatcacttca aaatcattgc gttacttgtt gctaaacagc
     7321 tttttcatga cctctgataa acggtgttca agtagctgac attcgacatt agttcaggtc
     7381 aaagcgctac tttcacaacc gctctttcaa ccatgttttc cgagtatttc caatgataag
     7441 cggaacagtt tcatgtttta cttcgctgta ctctagccca aaccatgttt ctggcgaggt
     7501 agcgattttt ttgattgcca gttttgcctg catgatttga cgttgccatt ttcctagagt
     7561 tgtcacattg gaaactactt catcaatcag gacaaattgg aaatcgccaa cttctcgccc
     7621 tggtgtcaga gagtatcttt gtggctgttt tggcaaacgg ccttgtttca tcaaatcatg
     7681 gatgacttgg cgaacatata cgttgatttc ctgttggacc ctgaaaccta agaacagatt
     7741 cacttggaca ataaaatcag tgtccatcat atctacttga tattctttcg tatatggctc
     7801 atccgtcact tccacatgaa caaaccaata gactcgtgct cttttaggcc gtttatctaa
     7861 aatcgaatag atgaactgtc ggccaacttt atcttcagcc atatcaggaa ccaagaagac
     7921 cacatttgtc tgatagattg gtaaagaagt atcatcacgt aattctctaa gctgcgggat
     7981 ataatctctc aaagacacat cctcggttga cgattcgcga ataatgttcc cttgttccca
     8041 aataaacatc acgactaaga tgatcaaacc aatcagaacg gctacaaaac cgcctcggaa
     8101 gaatttgaca acacttgaga taaagaaaac gacttctatc gcaccgaaga aaaaggtaac
     8161 taaatatgca agccaacgag aatgcccatt ttggataaga taaaagtaaa gcagtgctgt
     8221 tgtcatcaac atcgtcacag tgatcgatag accgtaagca gcttccatat gatgagacgt
     8281 tcggaatgtg acaaccacta gagaacaggc gatccataaa atcagattga ctgctgggat
     8341 atacatttgc ccgatactgt tcccaggata catgatcttt aaccgaggca gcagtttcaa
     8401 cttgattgct tctgaaacta gcgtaaacga acctgtaatc aatgcttgcg aagcaatgac
     8461 tgcagcgact gttgcaaaag caacgccgat cacgatccaa ctttgaggca tcatttggaa
     8521 gaatggattc aggttcttga tttgctgtgc ttcagggttt tgataaacat tcaacaacca
     8581 cgcagcctgc ccaaaataat tgataaccaa acaaattttg acgtaaggcc agctcagacg
     8641 aatatttcgt ttgccgacat gtccaagatc ggaataaagc gcctctgcac ctgtcgtagc
     8701 caggaaaata tttccaagaa tgaacaagcc taatttgtta tctgcactaa aaagcagctg
     8761 gatagcataa taaggattca gtgcacggat aactgtccag tcttgactga agttcattaa
     8821 tcccattacg cctaaaaaag taaaccaagc gaacatgatt ggtccgaatg cttttccgac
     8881 aatatctgta ccaaagcgtt ggaccatgaa taaaacaaaa ataataacta aagtgataat
     8941 gacgatcacg ttctggttat taccgaaccg gtcaaaaaac tgcggaattc ctcgcaagcc
     9001 ttcaatcgca gtcgttaccg tcacagcagg ggtcaatacc ccatctgcta gtaaggcagc
     9061 tcctccgatc attgcaggaa tgatcaaata tttcccacct tttcggacaa gtgtgtagag
     9121 tgagaaaatt ccaccttcac catggttatc tgcattcaat gcaatcacga catatttgat
     9181 tgttgtcagt agagtcaatg tccaaaaaat caatgagact gatccgataa caaaatcagg
     9241 attgattcct gacaatccgc cattatcttc aacaatcgat ttcataacgt aaagcggact
     9301 tgtcccgatg tctccgtaga cgactcccat cgctacaagc aggccagcca ttgatatctt
     9361 tttggtattg tgcgttgttg ccacgttttt ccctcatttc ttgttatatg gatatccttt
     9421 aggtaagctt gaatgataga tgatattctt atccatgaca cccgctttcc taaattgctt
     9481 ctaattatcc aagtaacaca ctgaagtgtc aacttatttg aataaaatta ttctttcttt
     9541 ggacgttctc tgatacgtct tgccacaaat gaataaagag caaggcaaaa aattgcaccc
     9601 aataatgctg gtatcaaata aaaaccgccg agttccggtc ccagtggtcc tagtaaaaat
     9661 tcgccgagcc aactacctaa aaaaccgata atgatatttc cagatacgcc tcccgggact
     9721 tcctttccta aaattgcgcc agctatcaaa cctaatatac cgccgataaa taacgaccat
     9781 aaaaaattca gcatctcctt tccctccttt atccatattt ctcactttta ttttacgctt
     9841 tattcagaag gactccaaaa atatgcgcca agaaactcca gaaaaaaaga agttgtaaca
     9901 aaagtgttca gcttatttcc gtagaagctg cttctggaac accgtgaatc agaggttgtg
     9961 aaatcagcgg tttgacctga gtattagaga aacaaacgga aaaatagttc ctcatatttt
    10021 gccgtttttt gagctaatat cgagggacag ctgattgaac atcgtttatt ggagaggttg
    10081 taaaaaagct gttctgcatc aagtaataag aacagccaag taaaaacagc tcctaatgtt
    10141 tttaacttgg ctggacttat taccgcagat gcaagctttt gaacaccgtt tattcgaaaa
    10201 aaaaggactg tgacacggct tttgtcacag tccccttttt tcgaataatt attgtccccc
    10261 tgtcaccttc acgatcacaa gtacattatt cctatgaatt aaattatttt tcttcatttt
    10321 tcgttgaacc atcttcgttc aacattgctt ttcttgacag atttacgcgt ccttgtttat
    10381 cgatttcagt tactttcaca aggatctcat cacctagttt aacaacatct tcgactttat
    10441 tgacacgatc gtttgctaat tgggaaatat ggacaagtcc atcttttcct ttgatcaagt
    10501 tgacgaatgc accgaatttt tcgatacgga caactttccc tagataaact tcaccaactt
    10561 tgacttcttt ggtcaaatct tcgatgatct tgatagcttt tttgatcatt tctgcatcag
    10621 ctgaagcaat acttactttt ccatcttgat cgatatcgat tttcacacca gtttcatcga
    10681 tgattccgtt gatcgtatcg ccgcctttac cgataacatc tttgatttta gcaggttcga
    10741 tctggatcat ttcgattttt ggtgcatatt ggcttaattc ttcacgtgga gcagcaatcg
    10801 ttgaagtcaa ttcttctaag atttccatac gtgcttgttt tgcttgagtt aatgcttcag
    10861 ttaggatttg ttctgtgatt ccttgaatct tgatatccat ctgtaaagca gtgataccat
    10921 cttttgtacc ggcaacttta aagtccatat cgccaagatg atcttccagc ccttggatat
    10981 cagttaggat cgtatagttt tcaccatcag aaacaagtcc catcgcaata ccggcgactg
    11041 gcgctttgat tggtacacct gcatccatca atgctaatgt gccagcacag atacttgctt
    11101 gggaagaaga accatttgat tccaatactt ctgctactaa acggatcgta taaggaaatt
    11161 cttcttctga agggattact tgtgctaacg cacgttcacc taatgcgcca tgtccgattt
    11221 cccgacgccc tggagagcct gcacgtcctg tagaaccaac agaaaattga gggaaattgt
    11281 agtggtggat gaatcgtttg ctgacttcca cccctaaacc atcaatgatt tggtgctctc
    11341 ctagaggtgc gagtgtacaa gctgataaag cttgtgtttg tcctcgtgtg aacaaacctg
    11401 atccatgtac acgtggcaat aagctgacct ctgatgacaa tggacggatt tcatccaatt
    11461 tacgcccgtc aggacggatc ttatcgatgg tgatcaattc acgtacgaca tctttttcaa
    11521 gatcttctgt gatttgttta acttctttca acaagtgatc ttcatcttca tgacctgcaa
    11581 atttctcagc ataagcttcg cggatatcga tcttcacctg ctcgatatta tcttcgcgag
    11641 caagtttttc ttcagtcatt actgctgctt tcattgtagc gtaagaagca tcaaagattt
    11701 cttttttcaa tacttcatca acttgcagta aagtcacttc cattttttct ttccctactg
    11761 cttgaacgat ttcttcttgg aaagcaacta actctttgat agcgtcaaaa ccaaacagca
    11821 atgcaccaag catgtcttct tctgaaactt ctttcgcgcc gctttcaacc atattgatgg
    11881 cttgtttcgt tccggcaaca gtcaattcga tatctgtttg ttctgcttgt tctactgttg
    11941 gattcaagac gtactcgcca tttacacgac caacttctac gcctgcgatt gggccgtcaa
    12001 atgggatatc tgagattgat agtgctaaag aagaacctag cattgctgcc atagctggcg
    12061 agcagtctgt ttctacactc atcacgatgt tcgttacttg gacttcatta cggaagcctt
    12121 ctgcaaacat cgggcgaatt ggacggtcga tcaaacgggc agtcaatgtt gcttccgtac
    12181 ttggacggcc ttctcgtttg atgaaacctc cagggatttt ccctgctgca tacatttttt
    12241 cttcataatt gatcgttaat gggaaaaagt ctgtatcttt tgcttcttta gaggccacag
    12301 ctgcacttaa gactactgta tctccataac ggactaaaac ggctccgttt gcttgttttg
    12361 ctagctgacc gacttcgatt tgtaagggac ggccgcccca tgtcgttttg aatacttgtt
    12421 tttctgacat aacttctcct tttccttctc gtgaaagcaa gacgctacta aacaaatgaa
    12481 aactgccgaa agccgtcttt tgagcagctt tcatttggtt agtaggagtc catctagctt
    12541 gatcacggaa ttttacttaa ttgatatacg agtaaaaaaa gtgagattca tgtgaatccc
    12601 actctttttg actaaaatta acgacgcaag cctaaacgtt tgatcaattc gcggtaacgt
    12661 tgaacgtcag ttttacgtaa gtaagctaac aagttacggc ggtgaccaac ttttttcatt
    12721 aggccgcggt atgaatgatg gtcttttttg tgcacgcgtg catgttcatt caagtggttg
    12781 atttcttcag ttaatacagc gatttgtact tctggagaac cagtatcccc ttcatggcga
    12841 gcgtattcgt tgatgatttc attcttgcgt tcttttgaaa ttgccatttc tttcacctct
    12901 ttcgattatt cccctgcgac tgagtaaaac gttggtgatt cgcttaacca agtggcaggt
    12961 catgtgccta gagcacacag ctatacttta cctgaaaccg ggttgaaaat caagtagtta
    13021 atcattaaga aaaggtagtt ttcaaacaat cttactacta cttttccatt tttgtggtaa
    13081 actataatgc gaaaatagac ttgaaacaca gtcttttaag aaaggggtac atattccatg
    13141 attacaatgg atgatatcat tcgtgaagga aatccgacct tacgcgaagt tgcaaaagaa
    13201 gtttctcttc cattaagcga agaagatatc tctttaggaa aagagatgct tgagttctta
    13261 aaaaacagcc aagatccaat caaagctgaa gaactacact tacgaggcgg tgttggctta
    13321 gctgctcctc aattagatat ttctaaaaga atcattgctg ttcacgtacc aagtcctgac
    13381 ccagaggcag atggaccttc tctaagtact gttatgtata atcctaaaat tttgagccat
    13441 tctgttcaag atgcttgttt aggggaaggt gaaggctgtt tatctgttga tcgagaagta
    13501 ccaggatatg ttgttcgcca tgccaaaatc actgtgtctt attatgatat gaatggtgaa
    13561 aaacacaaga ttcgtttgaa gaattatgaa tcgatcgtcg ttcaacatga aatcgaccat
    13621 atcaacggtg tgatgttcta tgaccacatc aacgatcaaa atccatttgc actaaaagaa
    13681 ggcgtattgg tgatcgagta gagaattggc aggttccttc gatactatgc tacaagaaag
    13741 ctttataaaa aaggggagtg ctcaaaagct gcacttccct tttttatgtt tctccactaa
    13801 tcgaaattta gatagacatc tagaaatcgc aattccaaaa aattctgtgt attggatacg
    13861 catcttttct tattttttct tatttcttcc atatgggtgt ttatctcaga gatgatagaa
    13921 tagtttctag gataaaaagt agcagctacg atgttatcct tcgtagagga ttcctgcttc
    13981 agctagtttt tgtttgatgt ttttcagcat atgcttttct gggtagcgga tcgtatgcag
    14041 atggatgccg cctgttaatt cggataacaa agtagcatta cttttttgat aacgtctcat
    14101 aaaggaatcg atatcttgtg gcgttttgat gtgcaaagtt cctgctaact caccgtaaag
    14161 gggatgttcc acaattacat caatgatttc accaccattt tcaacgatta gtctcagttc
    14221 ttcttctgtt tgatcttttc catgctggac agcgatttta ctgatgtgcc cagtattggt
    14281 ttcttctgtt tcgaggatat aacctcttgc tgttgccacg atacttttac ctgcagctcg
    14341 tagtaaagca atatcgccta caatgatctg acggctgact ccaaaagttt tcgcaaactt
    14401 gctagcactc actggttttt ctgtatttgc caaggtttgc atgatttgtt ttcgccgtgt
    14461 ctctccttcg atcacactta ttcctccttc attttgtttt ggtattcgcg cgagtgtttc
    14521 atcaaatcaa catacgtgtc tgttattgtt tccttatatc ccttattttt cagcagacta
    14581 acaactttat ccaatacttg ctgctctctt tttgcatcat aaactgcttg gttttcttct
    14641 tttttcactt gtcctatttt agttaccgta tccattcttt tttctaataa agcaaccaac
    14701 tctcgatcga tcatatcgat cttatgacgt aatgtttcaa gagactcttc tgttagttct
    14761 tcctctactg tcttgatgat acgagcagga tttcctgcaa tcactacatt gtcgggaaaa
    14821 gatttggtca caaccgaacc tgcgccgact actacgttgt cccctagagt gacacccggc
    14881 gtgacgataa ctcctccgcc taaccaaaca ttattaccga ttttaatggg ttttgcgtac
    14941 tccagaccgc tgttacgttt cactggatgt agtggatgcg tcgccgtgta aagctggaca
    15001 ttcggagcga acatgcagtt atcaccgatt tcaatcgtgc tgacatctaa aaatgtacaa
    15061 ttgaaatttg cataaaaatt ctccccaaca aatatattat atccgtaatc aaaattgata
    15121 actggctcca tatagatttt tttccctgta cggccaaaag tctctttcaa caattgggat
    15181 cgcagttccg ctgattctgc ttggttgatg atttggcttt gacttcttgc aaacatacgg
    15241 tcggcaacca gctcaggatc attggcaaaa taaagctcgc ctgcaatcat tttttctttt
    15301 tcggttttga attcagtcat aatctgctcc taattcttgt atttttttga aaacaaccgc
    15361 tccgtcttct tgaataaacg tataaggctc cgctaaataa acaggcgttt gattgattac
    15421 taagattttg gctgacggct ggcgaaactg taccagatca caaaacggat gaacttgaaa
    15481 actcgttcca acaatgacga tcagctctgc ttggctgacg gcataagccg cctgctccat
    15541 gactccatct tgaaaccctt caccatataa cacgatgtct gggcgtattt gtcctccgca
    15601 tgcttgatgt ttgtcgctgt gaagatattc tttccagtct accgtttgtt gacattttcg
    15661 acaatgacat tgatacagac tcccatgaaa attgacgagt tgcgggcttt tagcctttgc
    15721 gtgcaaaccg tcgatgtttt gggaaacaac ccaaacattt ttttctttcg ctagatgtgc
    15781 tatttccaaa tgaatgatat tgggttttgc ttcaggatga taaatctttt tgacaaattg
    15841 atagaattta tccggttcat tcaccattgc ttgatgactc agcaagtatt ccggctgctc
    15901 catcccgtgg tagattcctg acaaagatcg atagtctggc actccagaag gtgtggatac
    15961 ccctgcaccg gtcaaaaatg taatttgctg ataagctaat atctcttttg ctgcttcgtc
    16021 tactgttaat tgtttcatgt tttgtcacct cactttccat tatagcccat actcgaacaa
    16081 atttattgtt gaaaagtcag aaaaatggga ataaaaaagt gttatgggca tttgagcaat
    16141 ttatcacaat gttcactgac aaaagaatga aaacgtgtta caatactgct gtataaaagt
    16201 gaggtgaatc gatatgttac cattctttat ttattggggc gttattctgg cttgtatcgc
    16261 ctggttagcg ttaagcgttt atttctctgt tttttatctt gtacgcaaag aaaatggaaa
    16321 tctttgggct tttgctttat tcaacgtgat tgccgcaatt gttttagcca ttacattagc
    16381 cgtatatcga acatggggct ggggaatcac ccaatactca agtttgattt atctaatatt
    16441 agccatttat ggcgtcgttg ttcttttgca agcgatccta ggacgtgagc caaagaaagc
    16501 ggcagcttaa atgatcgaga tggaactgga cacaggaaat tttctgttct agttcttttt
    16561 ttattgtatt acatacattt ttgtgtataa ttatactatc gtttgcaatg gatagatgat
    16621 tcacattttg attgtttttt cggtaaaagt aaagatttct atatttatca gtattttttc
    16681 aaaaaccagc agttatagat tgacaaagcc tctcgagtat cgtaaacttt ttttgtataa
    16741 ataactgaat acgagatgcc tcaatcaatg aggtagaggt cgcgagaatc attaaccctg
    16801 tggagtgaag caaacatgga gaagcaggaa tagggaggat cgccgaaatg tgcacttttt
    16861 tgcttggagt gtatgttggg acgcaagtta agagcttgcg gactgtctta gcagtgatgc
    16921 taagttgcgc tatgttttgt gagaggttta tcaccttatg gaattttagc ggccttttta
    16981 tatctataaa tcggtcgctt tttatttttt cagataaagc tttaccgcat ttcatctaga
    17041 ccgctcgtgt atcatataat cagaaaggga gaaaaaaatg aaaaaaaata tggtttcagt
    17101 tgccgtacta tttgcttttg tcttctcact attcagtgtg ggatctctgg caaatgcaga
    17161 tgaaaaaaca ccgagcgatg agtttcgcgt aggtatggag gctgggtatg cacccttcaa
    17221 ctggtctcaa caaacagatg agaataatgc cttgccaatt caaggccaaa atagttacgc
    17281 cggcggttat gatgttcaaa tcgctaaaaa agtagcagat ggtttaggga aaaaattagt
    17341 catcgtccaa acgaaatggg atggtctggc tcctgccctt caatcaggca agatcgacgc
    17401 gatcatcgcc ggaatgagcc ctactgctga acgacgaaaa gaaattgatt ttaccgatcc
    17461 ttattacgaa tcacaattag tagtagtagt tcaaaaagat agcaaatatg caaaagcaaa
    17521 aagtttagca gatctttctg gagcaaagat cactgctcag ttaaatacat tccactatac
    17581 tgtgatcgat cagataccag atgtgcagaa acaacaagca atggataatt tctcagcaat
    17641 gagaacagct ttagcttctg gaatgatcga tggttatgtc agcgaacgtc cggaaggtgt
    17701 aacggcaact agtgtgaaca aagacttgga aatgcttgaa ttcagcggtg cagatggctt
    17761 ccagacaaac ccggaagatg ttcagatttc tgttggtatg cgtaaaggcg acccggatat
    17821 ccaaaaagta aaccagattc tttctggcat ctctaacgat gaacgaacca aaattatgga
    17881 ccaagcagtc aaagatcagc ctgctgcaac tgatagtgaa gaaaaacctg gcatcatttc
    17941 tgatttcact acgatttgga aacaatacgg caatatgttc ttacgaggtg ctggacttac
    18001 cttgttcatc gcattgatcg ggacagttgt cggtactaca cttggattac tgattggtgt
    18061 cttccgttcg gtacctgaat caggaaatgc actgactcgc ttcttccaaa aaatcggaaa
    18121 tgcacttctt tctatctatg tcgaagtatt ccgcggaaca ccgatgatgg tacaagcaat
    18181 ggtcatcttc tacggtctgg cactcgcttt tggcatttca ttgaaccgaa cgattgccgc
    18241 tttgtttatt gtctctctca atactggagc ttacatgaca gagatcgttc gtggggggat
    18301 ttttgcagta gatgaagggc agttcgaagc tgcgcaagcc attggtatga cccatggcca
    18361 aacgatgaga aaagttgtta ttccacaagt tttacggaat atcttgccag caacaggaaa
    18421 tgagtttgtt atcaatatca aagatacagc agttttaagt gtaatcggcg tagctgattt
    18481 gttcttccaa ggaaactctg cttccggtgc gaatttccaa ttcttccaaa catttacgat
    18541 cgtcgggatc atctacttag tcatgacctt tacgatcacc agaatcctgc gggcggtaga
    18601 aaagaaaatc gatggtcctt cagcttatac caagcttgaa gaaatcgaca attcaaattt
    18661 gcaggaataa ggaggaagaa tcatgaatga aaaaattatt gaaatcaaac atctaagaaa
    18721 aagcttcggt gaaaatgaag tattgaaaga tatcagcgta acagtcaata aaggtgaagt
    18781 tgtgacgatc atcggttctt ccggttctgg taaatctact ttcttgcgct gtatcaattt
    18841 actggaaaaa ccaacaggcg gcgagatcat ttataatgga gaaaatgtat tagctcctaa
    18901 atataattta cctaaatatc gaacgaatct aggtatggtt ttccaatcct tcaacctgtt
    18961 caacaatatg aatgtcttgg aaaactgtat gtctggtcaa acaactgtcc tgaaacgaga
    19021 taaagaaact gccaaaaaag tagcaatcga aaatctggaa aaagttggta tggatcgtta
    19081 tatcgaagcc aaaccagcac aattatctgg tggacagaaa cagcgtgtcg caattgctcg
    19141 ggcattatca atgaatccag atgtattgct attcgacgaa cctacttcgg cgttagaccc
    19201 tgaaatggtt ggcgaagtgc ttaatacgat caaagactta gcacatactg gcttgacaat
    19261 gcttatcgtg acgcatgaga tggaatttgc aaaagatgta tctgaccgtg tcatttttat
    19321 ggataaaggt gtgattgcag aagaaggtac accagaagat atctttgtcc atccgaaaga
    19381 agaacgtaca aaagaattcc tttcacgtat tttaaatgct taggatcaat agctgattgg
    19441 gacaaagagc tgcggtgttt accgcagttc ttttttatga attactcata aaaggtaaat
    19501 ttctgaaaat tttggaatct tagttgtgtt tttcagaaaa ctctcttaat atggaagtaa
    19561 ttaaactttt ttagttagga tgatttaaaa atgaatgaag agcaagaact gcagcgtgga
    19621 ctgaaaaata gacatgtcca actgatttct attggcggag cgattggaac ggggttgttt
    19681 ttaggttccg gaaagtctat ccagctagct ggcccttcga tattgctcgc ctatcttatt
    19741 actggatgca tctgtttttt cattatgcgt gcgttaggcg aacttctgtt atcaaacacc
    19801 aataaccatt cttttctgga ttttgttgca gaatatcttg gcaaaaaagc ggctttcatc
    19861 actggctgga cgtattggtt ctgctgggta tcgattgcaa tggccgattt aacagccatc
    19921 ggaatgtatg tacgctactg ggcgcctggt gttcctcagt ggcttcctga actgattgca
    19981 ttaggtcttc ttctttgctt gaatatggtg gctgtctcat tgtttggtga gttagagttt
    20041 tggtttgcat tgatcaaagt tgtagcgatc attgccttta tcctcgtagg agcttatatg
    20101 atcctcaccc actatacgac agatattggc acagccagta tcacgaatct atggtctcat
    20161 ggcggattct ttccaactgg tgcaaaagga tttatcttag ctttccaaat ggtaaccttt
    20221 gcttttgctg ggatagaatt agttggatta gtcgctggag aaacagaaaa tcctgaaaaa
    20281 gtgttgccgg aagctatcaa taatattcct atcaggatca tcttatttta cttaggatct
    20341 ctttttgtca ttatggcaat ctatccatgg aacagcttga atccagataa cagtccattt
    20401 gtagaagtat tttcggaaat tgggatcacg attgctgctt ccttgatcaa tttagtcgta
    20461 ttaagtgcag cagcttctgc ctgcaacagt gcaatatata gtacaggacg tatgcttcgt
    20521 tctttagcgc aagaaggcag tgcccctaaa aaattcaaaa agttaacaac acatcatgtg
    20581 ccagggaatg ctttgacatt ttctactatc gtcattttca tttctgttat cttgaattac
    20641 gtgatgccta gtgaagtatt cacactagta agcagtattg ccactacttg tttcttgttt
    20701 atctggagta tgcttgtcta cacgcacatg aaatatcgta aaagtatcct cggcaaaaaa
    20761 gctcattcat ttaaaatgcc gttgtaccca tttagtaatt atctggtatt tctttacatg
    20821 gcctttgtgt gtgtcgtctt gttcctagga aaagatacga gaatcgcttt attactaaca
    20881 cctgtgtggt tcttgcttct attactaatc tatcatatga aatatgaacg taagaagtaa
    20941 gaaagtagtt gtgacagaag tggtcagctt cgagaaataa gaaggaattt acgaaaattg
    21001 cttcttaaat ttttgtgaaa tttcggctta tttcttggag ataaaagctt ctgtcccagc
    21061 ctcttttcta tttccccgga aacaaccgct gataataggc atctgctttt ttataggaaa
    21121 aaatccaaat accagataca aaaaaacgtc cgaataaccc gatcaacggt acaaaaaaga
    21181 caccggcaat caagcataag ttaatcatca tggagataag acttcgacgg tcctttgaca
    21241 aaactctcac gacatgggaa tctggtttat ttgctttcat gatttgcctc atcaagatac
    21301 caaaagaaaa actccacatc gtgtatacta agacataagc catctcaggc caaaaagctt
    21361 cagggttacg cccgacccaa ctagtaacag aaggacataa agtcagccaa aagagcaaaa
    21421 agatattcga ccagaccact cggtaattaa ttcgttctgc catctgaaat atacgatgat
    21481 ggttcaccca gatcaccgca acaaatataa agctgatggt ataagctaat aatgtatttc
    21541 ggatgaccca taaagaatga aagctagatg tattagggat cttgatctct aatacaataa
    21601 ctctcaaaac aatggctacc actccatcag taaatgcttc taatctcgac tttgtcacga
    21661 tgattcctcc tcagatgatt cagcgctttt attttatcac ttacgttatt aaataaccat
    21721 cgttttatat agggaatttt ctgaaaattg ttgcatattt ttcgaaattt tgttactttt
    21781 aaaaaaaccg taaaggagtt atgtatgaca aaaaaattat catttaaaga ctatcttttt
    21841 ataggctcca tgcttttcgg tctatttttt ggtgctggaa atcttatctt tcccgttcat
    21901 ttgggtcaag aagcaggcgc tgctaccttt tgggcgaatc taggtttctt ggttaccggt
    21961 atcggtcttc ccttcttagg ggtgattgcc attggtgtat cgaaaagctc aggtgtatat
    22021 gaattagcaa aacggataaa tcaaacatat gcgatggttt ttaccatctt gctttactta
    22081 gttatcggac cgttttttgc tttacctcgc cttgcaacca catctttcga gattggttta
    22141 gcaccattta tcgatcctag cagacagacg ctatatctag caattttcag tattgtattt
    22201 tttgtgctgg cttggtggtt ttcaagaaaa ccgacaaaga tattagatta tgttggaaag
    22261 ttcctgaatc ctgcattttt ggttttatta ggtgctttgc ttctccttgc ttttttgaat
    22321 ccactaggtt ctgtaaatca agcgcctatt cagccaaatt atcaagagca tgcttttttc
    22381 acagggttta ctcaaggata taacacatta gatgcgcttg ctgctttagc atttgggatc
    22441 atcattgtca caacaatcca aaacatgggt gtaacaaaac ctgctgaaat cgctaaagac
    22501 acgatcaaat ctggtgcgat cagcattata ttgatgggaa tcatttatac tttgctcgct
    22561 tatttaggtg ctatgagctt aggtagcttt gctctaagtg aaaatggcgg gatcacgctg
    22621 gctcagattg ctgatcatta tttaggtact tatggcagta tcttattagc atttatcgtt
    22681 atattagctt gcttgaagac cggtattggt ttgattacag cttttgcaga aacattcaca
    22741 gatttgtttc cgcaaagaaa ttacgcattc tttgttgcac ttgctagtat ccttccttgt
    22801 ttagcggcaa acgtaggctt gacgaatatc attcaatttt cgttgcctgt tttgatgttc
    22861 atctatccat tagcaatgac actgatttta ctagtgttag ttggtccttt gtttaagcag
    22921 cgtacggctg tttatcgaat gactacttat tttacattga ttgcttcgat ttttgatggg
    22981 ttgaacgctt gcccagaaac tatcaaacaa acacctattg ttcaaaatct tttatatgtt
    23041 gcggaaagct acttgccgtt tttcaaattg gggatggggt ggatcgtacc agcagttatc
    23101 ggttttgtta tcggactgat ttggagtttc gctaagaaag aagaagtagc agattgataa
    23161 aagaggttgt gaaagagacg ttcagccttg agcaataaaa agtaattttg aaaaatggct
    23221 tctcacattt ttgcataaat ttgacttaat accgagaaac tgacttttga acaccgttta
    23281 ttgagaggtc gtgaaaaagc cgcttagttt caagtattaa gaaatatttt gtgaaaatgg
    23341 cttctcacat ttttgcataa atttgactta ataccgagaa actggctttt gaacaccgtt
    23401 tattgagcgt ctataaactg acctgagtat tagagaaaca aaacggcaaa gtagctccat
    23461 atactttgcc gttttgtttt gaactaatac cgaagagaag ctgatcaaac aacatttctt
    23521 ttataatata gattttagac atatatatga tataaaaata gttttcgcaa aa
//
LOCUS       DACDLM010000044        23550 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.044, whole genome shotgun sequence.
ACCESSION   DACDLM010000044 DACDLM010000000
VERSION     DACDLM010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23550
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.044"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            6..305
                     /locus_tag="IV356_001770"
     CDS             6..305
                     /locus_tag="IV356_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP9015458.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="IV356_001771"
     CDS             378..1739
                     /locus_tag="IV356_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HAP9015459.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="IV356_001772"
     CDS             1761..2021
                     /locus_tag="IV356_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015460.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="IV356_001773"
     CDS             2035..2787
                     /locus_tag="IV356_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HAP9015461.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="IV356_001774"
     CDS             complement(2881..3486)
                     /locus_tag="IV356_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP9015462.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="IV356_001775"
     CDS             complement(3539..4513)
                     /locus_tag="IV356_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HAP9015463.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5670)
                     /locus_tag="IV356_001776"
     CDS             complement(4891..5670)
                     /locus_tag="IV356_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP9015464.1"
                     /translation="MLLRVVGSIIFRYTLEEVNNVPKYEEIANILRERIRSKEYPLDS
                     FLPNQVDLVKEFGASRMTIKKAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEY
                     EGLSLQMKRRHRSLKSQIIHFDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVL
                     EHTFMPVHLVPGLKKEHLLASIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAE
                     NDPVLEVQQVVYLKDGQPIEYSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="IV356_001777"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="IV356_001777"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAP9015465.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="IV356_001778"
     CDS             7161..8558
                     /locus_tag="IV356_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP9015466.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="IV356_001779"
     CDS             8639..9079
                     /locus_tag="IV356_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAP9015467.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="IV356_001780"
     CDS             9227..9553
                     /locus_tag="IV356_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP9015468.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="IV356_001781"
     CDS             9554..10303
                     /locus_tag="IV356_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015469.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="IV356_001782"
     CDS             complement(10383..10838)
                     /locus_tag="IV356_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAP9015470.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="IV356_001783"
     CDS             complement(11265..11540)
                     /locus_tag="IV356_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015471.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="IV356_001784"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="IV356_001784"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HAP9015472.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12978..14429)
                     /gene="cls"
                     /locus_tag="IV356_001785"
     CDS             complement(12978..14429)
                     /gene="cls"
                     /locus_tag="IV356_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAP9015473.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14770..17436
                     /locus_tag="IV356_001786"
     CDS             14770..17436
                     /locus_tag="IV356_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAP9015474.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARFSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17800..18552
                     /locus_tag="IV356_001787"
     CDS             17800..18552
                     /locus_tag="IV356_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP9015475.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(18574..19728)
                     /locus_tag="IV356_001788"
     CDS             complement(18574..19728)
                     /locus_tag="IV356_001788"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HAP9015476.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            19913..22354
                     /locus_tag="IV356_001789"
     CDS             19913..22354
                     /locus_tag="IV356_001789"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HAP9015477.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(22684..23388)
                     /locus_tag="IV356_001790"
     CDS             complement(22684..23388)
                     /locus_tag="IV356_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015478.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
BASE COUNT         7529 a         4128 c         4875 g         7018 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaaa
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag ttgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    12721 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    12781 aggtcgtgag cctgccgtcc agctccgagt cacaaggaac aagttcaaaa aacagcttct
    12841 catgtttgtt gaatattgtg acttgtgacc gaggagttgg caggagaaca ccgtttgttc
    12901 ggaagaaggg actgtgacaa gatttttgtc acagtccctt taatcttagt atatttttct
    12961 ctacttgaat aaaaaaatta taggattgga gaaaataatc gagaaatttg ttgcttgaat
    13021 aatagccagt tagacatttc cttgactgtt tcagttgtca tggatgaaca atgtgtctca
    13081 tcttctttga actgagtagc aagttcttct aaaaactcag gatcgtaaat gacagcactt
    13141 gtttcaaaat tcaatcggta gctacgaata tcttgatttg ctgaacctac catgcagatt
    13201 tcatcatcca ttatcaatgt ttttgcatgg aggaagccgt tctcatagac aaggatttgt
    13261 acattttcct tgatcagctg ccgagcataa tattgtgttg ctcgataaat aaaaggatga
    13321 tccggtttgt tgggaatcat gattttcaca tctacaccag aggcagttgc gatttttaaa
    13381 gcagcaatga cactttcatc aggaacaagg taaggtgtct gtatccaaac acgtttttta
    13441 gcagaagtaa tcaatttgat aaatgaaagc ttgatttgtt ccctttcgtt attcggtccg
    13501 cttgaaacaa gctggatgga tgtatcagca agcttagatt catctcgatc tgctttttta
    13561 aagaaataat tcaaatgata gccgaccttt ttttcttcag gtaccgagac gttccagtct
    13621 gttaagaagc gaagctggag caaagaagaa gcggcaccga aaatccgtat atgcgtatcg
    13681 cgccaatagc cgaatttttt tgttgtattt acatattgat tggcaatatt gaaaccaccg
    13741 gtataactaa tctttccatc gatcacaacg atttttcggt gatcatggta attcaatcgg
    13801 aaacgaagta atgccctttg tgaggtaaca aatgtatgga catgtccacc atttttgatt
    13861 agacgattga aatcttttgc ttttgtgcca tgagagccaa atgcatcata taatattcga
    13921 acttccacgc cttctgcggc tttttcttct aaaacatgta agacttgctg gccgatatta
    13981 tctgtcacaa atgcgtaata ttcgatatgg atcgaatgtt tggctttttt tagatcttga
    14041 agcagtgaat ccaatttctc ttgtccgtct gtgagaagag tgacagaatt cattcttgtc
    14101 agcggcatac gatttaatga agagaagaag tcaacaaatt gctgtttgtc tttatcgccc
    14161 atgtcaggat cgtaatgttc aatggtatct cctctaaaag actgaaagtt ttctaattct
    14221 ttcaagtcac tttgtcggag atagaatttt ttcttatccg ttaatccacg tccgaaaaat
    14281 aaatataata caaagcccac cccaggaagg gcaaacaata ctaagagcca tgcccaaatg
    14341 gctgctacat ctcggggttt gatcaaaata gccaccaaag caataagtgc atttaataga
    14401 taaagggcgg ttataatact agataccaca aaaatgttcc tccttacata caataacatt
    14461 agtatagcat gatagaagaa agaagcctac caaggtgaat atacttttca ctcctttcat
    14521 gaaaatgtag gtaaatcggg ctaaagtagt tgctttttgt aggttaataa ggtaggatat
    14581 tagtacagtt gaatatctcc ttaggggagt aaccggcaac gtttgttgcg ataatatcaa
    14641 cagtaagtta accaaatggt tttctggtat tgtatgaaat ggtgagacct aagacaaatg
    14701 cgtatttgtc ttaggtctct tttttttcag acaggactag ggccaagatc aaaaaatggg
    14761 ggatgaaatt tggaaaacaa ggaacaagca caacaagcgg tctataaaga aacgatcgac
    14821 tcgttgatgc agcaaacgca gagctcaacc gatggattga gcaccacgca agcgaaggaa
    14881 aaattagaaa gagatggctt gaaccagcta aaagaaaagc cgaagaagcc aacttggaaa
    14941 ttgttcttag aaactttcaa agatgcaatg gttatcgtat tgctgattgt cgcactgatt
    15001 cagatggtca tgggtgacta catcgaattc ttagttattt ttgcagtatt gatgttgaat
    15061 tctataatca gtgttgtcca aacaaaaaaa gcagaaggtt ctttagaagc gttgaaaaac
    15121 ctttcagcgc ccgatgctcg agtgattcgt gatggtaagg aaaaaacgat tccggcaaac
    15181 gaacttgtgg taggagatat cgtgttgtta gacgcaggcg attatgtacc tgctgatgga
    15241 cgtttactag atgcgggatc attaaaagta gatgaaggta tgctgacagg agagtcgact
    15301 tctgcagaaa aagaagtaac ggatatcaca agtacggtac caatcggaga tcgtacaaat
    15361 atggtattca gtggaacgat cgtaacttac ggacgcggta aattcttagt gacttcaact
    15421 gggaataata cggagatcgg acaagttgct ggccttttgg aatcaacaac tgagcaagtc
    15481 actccgttac aacgaggtct ggataaattc agtaaaaaac taagtttggc tattttggca
    15541 ttgtctttat tgattttagg tatccaactg tttcgtattt atcttggaga aggtacagga
    15601 gatatgactg cagatatcgt cagcgcagtg atgtttgccg tagccgtagc cgtagctgct
    15661 attccagaag cattacagtc tatcgtaaca atcgtgttat ctttgggaac gaataaaatg
    15721 gcaaaacgtc atgccattat tcggaagctt ccagcagttg aaacacttgg ttcgacaagt
    15781 atcatctgta cagataagac tggtacattg acacaaaaca aaatgacagt tgttgactac
    15841 tttttaggta atggcgatac tggggatttc acaaatgacc cttcaaaatg gacagctgac
    15901 gaacgtcgct tgatcgaaat cagtgtttta gcgaatgatg catcgatcag tgaagacggt
    15961 actaaattgg gcgaccctac ggaagtagcg tttatcgact ttagtgaaaa attaaaccag
    16021 ccttatcagg aaatccgaaa caactaccca agacaagcag aacttccttt tgactcagat
    16081 cgaaaattaa tgtctactgg acacacaatt gataacaaaa attacttgtt tgttaaaggc
    16141 ggaccagata tcgtcttcca acgcagtaaa aaagtattgc taaatggtga agtcgttccg
    16201 atgacggatg aattgatgaa aaaattccaa gagcaaaatg aagctttttc aacacgcgca
    16261 ttacgtgtac tagcttttgc ttaccgtcca cttgataatt ttgatttatc atttgaagat
    16321 gaagacgatt tgatccttgt tggtttgctt gctatgatcg atcctccacg tgctgaagtg
    16381 actcaggcgg taacagaagc aagaagtgca ggaatcaaaa caatcatgat tactggtgac
    16441 cacaaaacaa cagctgttgc tatcgcaaaa caaatcggga tttttgaaga aggaaacctg
    16501 gctttgaccg ggacggaact agatgaattg acagaagatc aactaaacga agttttagaa
    16561 aaagtcactg tttatgcacg tttttcacct gagaataaaa ttcgtatcgt tcgtgcttgg
    16621 caaaataaag gtcatatctc agctatgaca ggtgatggtg taaatgacgc accagcattg
    16681 aaacaagcag acatcggaat tgctatggga acgggtacag atgtggcaaa agatgcagca
    16741 gcgatggtat tgacggatga taactttgct tctattgtca gcgcagtaga agtaggacgt
    16801 aatgtgtttg ataatatcaa gaaagctatt tcttatctat ttgcaggaaa tttaggtgcg
    16861 atcattgcga tcatctttgc cttagttgct gactggtcca atccatttac agcattacaa
    16921 ctgttgttca tcaatttagt caatgattca ctgccagcaa ttgcattagg tacagaaaaa
    16981 gctgaacctg ctacgatgaa ccgcccgcca agagatccaa attcaggaat ctttacggac
    17041 aaaacattga tttctgtaac gtatcgtggt gtgctgattg ggattgctgt tatctttgct
    17101 caatggcttg gcatgcagca ttcacctgaa ttcggtgtag ccatgtcatt ttcaacattg
    17161 atttggtgtc ggacattgca aacattccca gcacgttcaa acacacaaac agctatccaa
    17221 gcagggttct tctctaacag aagtgtctta ctagctgtag ttgtatgtag cgcgctttac
    17281 tgcttaacaa tgatcccagg actgaaagaa gtcttctcta tcccatcagc atttggattg
    17341 acagaagtct ttacatgtat gggaatcgca cttgtgacaa ttgttttgat ggaaatcact
    17401 aaattgatca ttgtacgagt acaaggaaat aaataaaacg aatcaacgag gttgtgagcc
    17461 tgccgtttaa ttctgagtca caaggtgcaa tttcaacaaa cagcttctca tgtttgttga
    17521 atattgtgac ttgtgaccga agagttggca ggagaacacc gtttaaggaa gaagttgtaa
    17581 aatcagcatt ttgagctaat actgagggtc atctgattgg acactgttta ttcggaaaga
    17641 gggactttga cacgactttg gtcacagtcc ctttttttat ttatgataga cggaaagcca
    17701 atcattttat tattcatcaa aagagataga atagataaaa gaggagaatg atttattccg
    17761 aaaagtgaaa acatataaca aaaaattaga ggaaatcaaa tgaatgaaaa agaatgggat
    17821 gaatttgctg aagaatatta tgaaatccag caagaatcgc aagtaactat tgctgaagat
    17881 gtaaaaaatt atctgaaaac ggagaaagtc ctgcctgctg aaacagcagc agacgttgct
    17941 ggaggatctg gcagatttct ttccttagca aaagaaatta atcgctatga tttgatcgat
    18001 ttttcttcag gaatgctaga aaatgcaaaa aaagaagcag aaaaaaatga gttgccaaat
    18061 gtttccttta tcaaacagtc gttagaagaa tttatccaat caaatgagac atatgaaatg
    18121 gtttttacag cagcaaatcc agcattggta catcttattc aattagaaaa attgatgaaa
    18181 aagtcaagca aatggtgcgt gataatcaga gtagtggaat caatcgatga tgttttttat
    18241 cctatcgaaa agcaactagg aatgatagaa gaagatccta atacatcgcc agttgtaatg
    18301 gatcaatttg aaacatactt aattgatgaa ggattcaaag tgaagaaaaa agattttact
    18361 tattttacac aggaatcaat tactgaagaa ttgatgaagc tatactatga cgcgtacgca
    18421 aaagatcctg ttgtgaccag gtacattcgc aaactattca gtgaaaaacg agaaatcctt
    18481 agtacgacta agctgaccta tagactgctc ctttggtccg cagataaaaa aagaaccttt
    18541 cacgactcgt gaagggttct ttttatgatt ttattatatt ttgtagtaac gaatatcatt
    18601 ttcgatcttt gtaatcgaaa aaggtacatc tgaagtatat tctgcacatt ctccgtgttc
    18661 aggaagcgtc tcactgaaaa tcgtttcata ttcgtcaaca gtgatccgtg ttcgagaatc
    18721 tagcatctct tgatgagatt gtgcgaagag atattcttga tagttttctt ccagataacc
    18781 tgtaaaaaat tcacttactg caccagaacc gtagctgaat agaccgatgc gatctcctgg
    18841 ctgtagtgat ttcgaatttt ccagtagaga agttagcccc aggtataatg aaccagtgta
    18901 aagattaccg attcgtcggc tgtaacggat gctttcttca tagcgagcca taagacgttc
    18961 ctgattttct tcgtctgttt ggtctaatac gctttgcaat gccttttttc ccatcttagt
    19021 atacggaata tggaaagcaa tcgcctgata atcttcgagt cctcgacccg acaattcttt
    19081 atgtcgattc caaacttttt ggaatgattc gatatacgta gaattagata aaggaccatc
    19141 aacaacagga aattcgctat aatctggacg ccagaaatca tagatatctt ctgtcagaaa
    19201 tacgctgtcg tcttcaatcg ataaaatacg cgggttttga gtgatcatca tcgcaacagc
    19261 accgacacct tgcgtcactt caccaccgct tgccaagccg taacgagcaa tatcacttgc
    19321 tatgactagt acttttcgtt ctggatgatt tttgacatat tctttcgcca tgtgcaaagc
    19381 tgcggtgcca ccgtagcaag cctcttttac ttcaaaagaa cgagcaaaag attggatttt
    19441 cagtaaatgg tggataatta ccgcactcgc ttttgaatga tcaatcccgg attctgttcc
    19501 gacgatgacc atgtcgatta gctcacggtc tttttctgtt acgattttgc tggcagcatt
    19561 tgctcctagt gtaatgatgt cttcatttgc acgattgact gccatttggt cttgaccaat
    19621 ccctatatgg tattttgcag gatcatcccc acggctttct gccaactctg tcatatctaa
    19681 atataaatta ggaataaaaa aggaaagacg atcaatccct attttcattt caacacctct
    19741 ttacttatga taaaaaactt actttactaa ggtatcataa aaagattaaa agaaatataa
    19801 aaaagagaat atttaaggat tgttaaaatt taatcttaga aaaaaataac tggaacaaga
    19861 gctatttgtt tttacagcaa agaatggtat atttttgtag gaggtggctt acttgaaaga
    19921 agtcgttatg atagatgctg caagaacgcc gataggaaag tatcgcggaa gtttaagtcc
    19981 atttactgca gttgaattag gcacacttgt gactaaagga ttattagata aaacaaaact
    20041 gaaaaaagat aaaatcgatc aagtaatatt tggaaatgtc ctgcaagctg gtaatggtca
    20101 aaatgttgcc agacagattg ctttgaacag cggtctccct gtagatgtcc cagcaatgac
    20161 gatcaatgaa gtttgcggat ctggtatgaa agcagtgatc ttagcacgcc agctgatcca
    20221 attaggtgaa gcagaacttg tgatagccgg cggaacagag agtatgtctc aagcacctat
    20281 gctgaaacag tatcagtcag aaacaaatga atatggtgaa ccaatttcca gtatggtcaa
    20341 cgacggattg actgacgcat tttcaaatgc acatatggga ttaaccgcag agaatgttgc
    20401 aacacaattt tctgtgagca gagaagagca ggatcgctat gccttgtcgt cccagttgaa
    20461 agcagcacat gctgtcgaag ccggtgtatt ttctgaggag atcatcccag tcaagatttc
    20521 tgatgaagac gtgttatctg aggatgaagc agttcgtgga aatagtacat tggaaaaact
    20581 gggcacgtta cgtacagtat tctcagaaga aggaactgta acagcaggaa atgcttcccc
    20641 gttgaatgac ggtgcctctg tggtgatcct tgcatccaaa gaatacgcag aaaataataa
    20701 tctgccttat ttagcaacca tcaaagaagt agcggaggtc ggtattgacc caagtatcat
    20761 gggaatcgct ccaatcaaag ccattcaaaa attgacagat agatcaggaa tgaatttatc
    20821 aacaatcgat ctttttgaga tcaatgaagc atttgcagct tcttctatcg tagttagcca
    20881 agaactgcag ttagatgaag aaaaggtcaa tatatatgga ggagcaatcg cattaggcca
    20941 tccaattggt gcaagcggtg cacgtatctt gactacatta gcttacggat tgcttcgtga
    21001 acagaagaga tacggtattg cttcattatg tattggtgga ggtttaggct tggcagtctt
    21061 gttagaagcg aatatggagc aaacacataa ggatgtgcaa aaaaaaaagt tttatcagct
    21121 tacgccatct gaacggcgca gtcaattaat agaaaaaaat gtattgacac aagaaactgc
    21181 gttgattttt caggaacaaa cactttctga agagctctcc gatcacatga tcgaaaacca
    21241 agtgagtgaa gtggaaatcc caatggggat cgcgcagaat tttcaaatca atggcaagaa
    21301 aaaatggatt ccgatggcaa cagaggaacc atctgtcatt gcagctgcaa gtaatggtgc
    21361 aaaaatctgt ggaaatatct gcgcagaaac acctcagcgg ctgatgcgag ggcaaatcgt
    21421 tctatcagga aaatcggagt atcaagcagt gatcaatgca gttaatcatc gaaaagaaga
    21481 gctgattctt tgtgcaaatg aaagttatcc ttcaatcgtg aaacgcgggg gcggtgttca
    21541 agatatctct actcgggaat tcatggggag tttccatgca tacttatcta ttgatttttt
    21601 agtggatgta aaagatgcaa tgggcgctaa catgatcaac tcgattcttg agagtgtggc
    21661 aaacaagtta cgggagtggt tccctgaaga agagattcta ttcagtattt taagtaattt
    21721 tgctacagaa tcattggctt ctgcctgttg tgaaatccca ttcgaacgct tagggagaaa
    21781 caaagaaatc ggtgaacaaa ttgccaaaaa aatccaacag gcaggggaat atgcgaagct
    21841 tgacccttac cgtgcagcaa cgcacaacaa agggatcatg aatggtatag aagctgtagt
    21901 ggcagctaca ggaaatgata cacgtgcggt tagcgcttcg atccacgcct acgcggcaag
    21961 aaatggatta taccaaggat taacagactg gcagatcaaa ggggataaac tagttggaaa
    22021 actaacggtg cctttggctg ttgccacagt aggcggagct tccaatatcc tgccaaaagc
    22081 aaaagcatct ttagctatgt tagatattga ttcagccaag gaactagcac aagtaattgc
    22141 tgcagtaggg ttagctcaaa acctggctgc tttgcgtgca ttagttacag aaggaatcca
    22201 aaaaggccac atgggacttc aagctcgttc attagcgatc tcaattgggg ctattggtga
    22261 ggaaatcgag caagttgcga aaaaattacg tgaagcagaa aagatgaacc agcagacagc
    22321 tatacaaata ttggaaaaaa tccgggaaaa ataaaaaagc aatatcttta gaagaataaa
    22381 gcaagattta cagttatttt atttactgca gatcttgctt ttttctctat cagaaaatat
    22441 gtttattatt agaatttttt atagttaagg ttaggcatct taagaaatca ggcaactcca
    22501 agatatcttc aggtagaaga gaagtcgcct aacattgtag gatcataggt gatttgttgg
    22561 acaggtcaag ctgatatttg agcctgatgt tagaaggaat ttctttttac ttgctgtaga
    22621 aattattata tgactaaaaa ggctgggatt ttaaatccca gccttttatg acaaatagaa
    22681 tttttatcga tcagtaatcg ctgtcgctgc aaattgttcg atcaaaggaa tcaaagtcaa
    22741 tttgactttg tatttccgtt cgagtgcttt ttcgataacg aactcatttt cagtagtcat
    22801 agaaatagtt gctaatttac gaggttcatc agcatttttt tcattaataa ctacttcatg
    22861 ttcattttgt tctgtgtaaa atttaggata ctcagcaacg gcttttgaaa aatcagcaaa
    22921 acttaaagcg gcattcgtat cagttgagcg tgtattttca gttgtgtccg cttttggttt
    22981 ttccgttttt tcttctggca cactgactgt ttcttctgta actggtgtcg caacagcttg
    23041 cgcagttggt tcatcgtttt tcaatcgttg atcattccag taagacacga tttcaataag
    23101 aagattgtca cggaatcgtt cgaaaatccc gttttctcct gaacgaattc tctttaatac
    23161 agtattgaag ttgtcatcga ttggcacgtt gatccgtgta tcttcatttg ttttcccagc
    23221 taatccgatc gttaagattt gacggttttt gggatcaagc atgacttgta acggcaaacc
    23281 ataacgtcgc aagctctctt cttctagaga acggaataat tgtcctctta caccatccaa
    23341 tgaaggacgg aattgattta ataatttttg tttctgtttt ttcttcatat gttctctcct
    23401 tcgctcatac cctttcgatt ataagaaaaa aacagccaaa tgaaaaggag taatgcaaaa
    23461 aaacttgcgt atacgcaaat tacaacagaa aaatttgcgt attttcccgt tttttgaaag
    23521 aaaaataaaa aatggaacgg attatgtata
//
LOCUS       DACDLM010000045        23432 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.045, whole genome shotgun sequence.
ACCESSION   DACDLM010000045 DACDLM010000000
VERSION     DACDLM010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.045"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(10..2154)
                     /locus_tag="IV356_001791"
     CDS             complement(10..2154)
                     /locus_tag="IV356_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP9015479.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQTADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFEPVPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(2511..3884)
                     /locus_tag="IV356_001792"
     CDS             complement(2511..3884)
                     /locus_tag="IV356_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP9015480.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPIMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(3884..4279)
                     /gene="rbsD"
                     /locus_tag="IV356_001793"
     CDS             complement(3884..4279)
                     /gene="rbsD"
                     /locus_tag="IV356_001793"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002829567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HAP9015481.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGSEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(4307..5224)
                     /gene="rbsK"
                     /locus_tag="IV356_001794"
     CDS             complement(4307..5224)
                     /gene="rbsK"
                     /locus_tag="IV356_001794"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HAP9015482.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(5333..6346)
                     /locus_tag="IV356_001795"
     CDS             complement(5333..6346)
                     /locus_tag="IV356_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP9015483.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQISHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEESGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(6427..7029)
                     /locus_tag="IV356_001796"
     CDS             complement(6427..7029)
                     /locus_tag="IV356_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP9015484.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKGIVNNGTLSPHTAQSILTNN
                     DLLAKTLKRTAALKVLVNVDITTFSYLSHQTDAGGISALSAPAEFTDLLLKDSLKDTN
                     NMLTITKYNPSAFFGTSLDLQLRRRGIETIVLSGVATTNGVYATALDAFQHGYHVVLA
                     EDACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            7214..7915
                     /locus_tag="IV356_001797"
     CDS             7214..7915
                     /locus_tag="IV356_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9015485.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            7925..10636
                     /locus_tag="IV356_001798"
     CDS             7925..10636
                     /locus_tag="IV356_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAP9015486.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEHNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKITEGKAQIAQGRTQ
                     LEDAKKQLAQQSAAIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKAAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWSYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            11033..12661
                     /gene="treC"
                     /locus_tag="IV356_001799"
     CDS             11033..12661
                     /gene="treC"
                     /locus_tag="IV356_001799"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HAP9015487.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRITIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(12721..13902)
                     /locus_tag="IV356_001800"
     CDS             complement(12721..13902)
                     /locus_tag="IV356_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP9015488.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSVW
                     LVPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            14154..15680
                     /locus_tag="IV356_001801"
     CDS             14154..15680
                     /locus_tag="IV356_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAP9015489.1"
                     /translation="MKRLIGILAMLVLAGMLTACGGASGKAEDSKEKLSVMTTFYPMY
                     DFTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQK
                     TLQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVAN
                     IRDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLAL
                     EYGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGV
                     SLEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNG
                     YFEDEDVQDRSLSDWAGTWQTVDTYVEDGTFAPVFEYKEKLNQDKTAQEYKEYYTKGY
                     QTDIASIKISEKEMAFTFKDGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGA
                     FRYIQFRDHTIAPADSEHFHLYAGNESQEALLKEMENWPTFYPDTMDGREIAQEMLLH
                     "
     gene            complement(15749..16477)
                     /locus_tag="IV356_001802"
     CDS             complement(15749..16477)
                     /locus_tag="IV356_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP9015490.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(16490..17770)
                     /locus_tag="IV356_001803"
     CDS             complement(16490..17770)
                     /locus_tag="IV356_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAP9015491.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIALSAFLSALLAFCFKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYAQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLVVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(17911..18513)
                     /locus_tag="IV356_001804"
     CDS             complement(17911..18513)
                     /locus_tag="IV356_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory regulator AgrB"
                     /protein_id="HAP9015492.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFALEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            18759..18965
                     /locus_tag="IV356_001805"
     CDS             18759..18965
                     /locus_tag="IV356_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015493.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            19278..19997
                     /locus_tag="IV356_001806"
     CDS             19278..19997
                     /locus_tag="IV356_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAP9015494.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(20078..20761)
                     /locus_tag="IV356_001807"
     CDS             complement(20078..20761)
                     /locus_tag="IV356_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HAP9015495.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            20993..23179
                     /locus_tag="IV356_001808"
     CDS             20993..23179
                     /locus_tag="IV356_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAP9015496.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
BASE COUNT         7812 a         4210 c         4583 g         6827 t
ORIGIN      
        1 taatttattc tatttcttta aaggcagatc aagccagaat gatttgtcta aacttaacaa
       61 ggttagtaca ggaacagttg cagctttaac tgtacgagta gttgtttctg gtatctgtct
      121 tgccgtaaaa ttgttccaca aatcccagat tgaagcgaca cggaagatgg aagaagcgtt
      181 gttgacgcgt tttatcgttg aaaattctaa tcctgtgatt ggcacgccat ctgttgtcca
      241 tttgattggc acatcgaatc gcttagacat attgaggatt tcagcgtttg cttcttcagt
      301 tgttgctgct tcttttttcg gttcatcata ttttgtcagg tcgtacgctt cgatgatcgc
      361 gttcaatttt tgtgaatatt ggcgatctgt agcataacgt ccttccaaat atttggttgc
      421 ttctttgtag tcttttgttt ccgacttcca agttggtttg tagaaatcag gattgccagt
      481 cagtccattt ttgatcaagt cggcatagtc ttccaaactt tccttgtaag aaggatattt
      541 acggaattgt gcgcggattt ggtagctttg tccggaacta tcttgttcaa gtgtattgaa
      601 ggtcacgctg cttcctttat atgatccttt gataccaaaa aggttatgat ttggttcgct
      661 tgataataag ctgtttccag atccactttc aaggatagct tgagccatca tgactgatgc
      721 gtagattcct tctttttgcc cgatttcctg tgcatcatct gcaatctttt tcaagaactg
      781 atcagttgtt tggttttgac tgaaatggaa cgagccatct aatccatcta aaatagatga
      841 gccgcctgtc agcgaacctg aagcagcagg taaacctgct aagtttactc ggacagcaaa
      901 atcaggcgtg aaatctgaaa tagaagttac tcgaacttta tctcctggtt gaggcgcatg
      961 gataaattgt ccgttcccaa tatagatacc tacgtggtgg gtaacaccag aagaaggtcc
     1021 ccagaagacg agatcaccag gttgggcctg acttactgga atctgtgtac ctgcatattg
     1081 ctgttcgcct gtccagccac cgatataatg accggttgct ttcatatata cgtaataagt
     1141 caaaccagaa cagtcaaaag tatttggacc ttttgctccc catacatatg gttttccaag
     1201 atgcttgaat gcttctcgaa cgattgcttg ttggacattc gttgtatttg taggcaatac
     1261 agcatcaatt ggtgatttta caacaaaatc agaagaagca gaagatggat tctctatacc
     1321 gctttgattt gctgtatttg gacgagatga agcattgttc gttccgccat ttgatgaacc
     1381 attgtttgga tggtttggtt ctctctgagt atttccattg ttattcgatc cagatgggtt
     1441 tgtttgattc gaagaattcc cgctgttcga attattgtta ttattgtttg aattatttga
     1501 accattatta ttgttgttat tacccacatc tggtttgttt ggcgtttccg gatctggtgt
     1561 actagggact tcttcactag gatcagttgg tttctctgtt gaagtatccg gtacaggttc
     1621 aaattctgca gtaatagata aattgttcgt acctactgta aaggtctttg catcataatt
     1681 tacttctttg gcaccattaa cagcgactga agcaatttgt tcaccttcag ctggcgtaat
     1741 agtgtaagtt accttcgttt ccgctaataa accttctacc gttccacttt ccgtaatatc
     1801 caaaggttgc tgttcagggg aatccgctgt cgaagcagtc agttggatct taccaatcaa
     1861 agaaggagca attgtaaggg aatatgtctc ggctggcttt tcattttctg atggatcagc
     1921 cggatcaatt tcagttggct cggtcgatcc tgttgttgag ttagttgttc cagttgggtc
     1981 ttctgtaaaa gaatccgttg tttcactagt agctgagctg gatgtagtcg tatctgttgt
     2041 gactgtttga tcagctgttt gattatctac ggcaaatacg gtattggtcg acaaaacaga
     2101 cggagcaatc agccaagtag cagctagcaa acgtatcgtt tttttatttt tcataataaa
     2161 ctagtccttt tcctttcatt gattttctgt cttattcagc attcattaga cattttttgg
     2221 aacagataat cgtgtcgaaa agctttttct tttcataaat ctgtctgtgt attctaaata
     2281 aaacaatttg taaataagca acgagcattc attcgttttt cattgacgtt cattttattg
     2341 catagaccac ctttgtttgg ggataaacaa gtggggataa aaatggttat gcatatgtaa
     2401 attataccaa agtttggaaa gtatcacaaa aatttataaa aataatgatc ctaaaaagaa
     2461 aaagactgaa atatgtgata aacatctcat acttcagtct ttttcattaa ctattcataa
     2521 gacattaggt cttcatcaaa cccgctaacg agagtagtaa tcattgctac gactagacta
     2581 acagccagtc ctgctaagta ccagaaaaaa gtaccggaaa tgaatgcagg caatgtggtc
     2641 agactaccaa atacaaaagc gatcgctttc acttgggcaa atcccattac agctccacca
     2701 gcagctgcac caatgcaagc agcaacaaat ggttttttca atgggatcgc aattccgtaa
     2761 acagttggtt cggtcactcc cgcaagtaaa atcgaagcaa aagcagaacc ggagatcgaa
     2821 cgagtttttg aacgtttact tcgtagaaat acacctaaag ctgcaccagc cattccaaaa
     2881 ttggctgctc ctgtcaacgg aacgattcgg tcgaacccat aagcagagat attactgatc
     2941 atgatagggt ttacagccca ttggatacca aatattacca aaatattcca accaccagcg
     3001 atgattgcgc cgctgatcgg tccgttaata tccatcatcc aagtaattgc ggcagctaaa
     3061 ccttcgccaa ggtaaacacc cgcaggcccg aataccatta acgtcaaagg aaccgtgata
     3121 actaatgaaa gtaaaggtac aaatactaat tgcatatttt cgcgaatata ttttttgagg
     3181 aatttttcaa caaaagaata aaagaaaata cctaaaatcg ccggcatgac agtagacgta
     3241 tactgcatca gtactacagg aatccccaga aaatcagtag ctgctttgcc actgtctgaa
     3301 agtaaagagg tcagattcgg ttcaatcagt gctgcagcaa tgacagccgc aatatatcca
     3361 ttcactttaa acgttttggc ggcagaaaaa gcaagaaaga ttggcagaaa ataaaagacg
     3421 gcattcgacg cagcagacaa aatatgataa gttccgcttg tttcactaag ccagccaatc
     3481 gtagtcgcta aaacaaccag accttttaat ataccagaac cggcaaacag cggaatgatc
     3541 ggcgtaaaga tttccgatat caaaccaaat agtttttcga tcggatttag cttttcttta
     3601 ggagctgaat gatcgatttg acgcgttaat tccttgtaag caggagccaa tccctgatcc
     3661 atgattattt ctgcatatct atcgagtaaa atgaaatact taatggaagg gatttgctgt
     3721 tttaattttt ctgcattggc tactggctgt tttttcaatt tgatacgaag ccgagtcgca
     3781 catggaagga cagaatcaat attgtctttt cctcccaact gttcaatcag catatgaatc
     3841 tgctcggaca gtaccatctg ttcaggattc attgtcgttt ccattagaag accactccac
     3901 tcactaatat aatattggcg taaggtgtca tttcgcctgt acgaataaat gcatgacagt
     3961 tattcaactc ttttttcatt tcttcatgtg ggataaagct aatcggtgta tctggtaaca
     4021 ataatttgat tttttccaat atttccgggt tcattgtctt tatttcttcc gccaattcaa
     4081 tcgattgtac ctcaagttct tctaaaacgt tttctaaaac agataaaaag cttggaagac
     4141 cgtttgagac agccaaatct attttttcac taccaaaggg gacaggcatg cctgcatccc
     4201 cgatacttaa tttatcaaag tgccccattt gtgcgattac tcgtgaaata tctgaattga
     4261 ttacttttcc ttttttcatg tttgtttctt cctctcattg ttaattttag actgctgatt
     4321 gttctaaagc ttcgcggtaa gggatagaag gttgcgcacc ataagactgc acagcaacag
     4381 aagaggctag atttccataa aggatcgctt ctttcaagtt actaaggtct ggctgaagtg
     4441 tgctgcttaa tgcgccaata aatgtatcac ctgcggctgt tgtgtcaacg gcatccactt
     4501 taaaagcagg gacgataccg tgttcttttt ctgtatgata gaaagcgccg gcactgccta
     4561 gtgtaatgat tactgttcca atacctaatt catggagttt ttcggctgct gcgaccaaac
     4621 tgttatgatc tgtcactctg attcctgtaa tgatttctgt ttctgtttca tttggtataa
     4681 tgatatctgt tttttcaagt agttcagtag ggatcgtttc acgagctggt gcaggattca
     4741 ggatcgttgt ttttcctgcg tcttttgcaa tagaaaaagc taggatcgtc gcatctaagc
     4801 tactttcaaa ctgagcaata ataaagtcac tgtttgtaat cagttgcttg ttttttagga
     4861 cttcttgttc atggaaagca ttatttgcac ctgcatggat caagatacta ttttctcctg
     4921 ctgcgtctac cataatcatt gcttgtccgg ttgtggcgcc ttggatttca gctatcccag
     4981 atgtatcgat gttttctttt gtcagtagat ctaataactg ttgtccttcg ctgtcagccc
     5041 caacgcctcc aataaaagat gtccgtgcgc ctgaacgttt ggctgccact gcttgattgg
     5101 cacctttacc tccgccagcg tgaaaaatct catgcgcatg cattgtttcg cctggcttgg
     5161 gcatgttggt taaacgaagg gtagtgtcca tattaatact tccaattact gtaaccgtgt
     5221 tcattttaca aacctccaac tatctcattt attttgatgg gaaaaattat tttttaaaac
     5281 gttttagtaa aacgttttaa tagttcgata aaaatatagc acaccttgaa agctatttca
     5341 agggtgcagt tgaaaatctt ttttctaatc gtacaggtaa tcttttttct tcccattctt
     5401 tttctgggaa ttggatccga tctaacaata atttggcaga tgtttgtccc aattcgaaga
     5461 tcggttgtgc gatcgttgtc agtttcggct tgatatactc gcacatatct atattatcat
     5521 agccaataat gctgtagtct tcaggaatgc tttttccaga ttcctctaat ccgcgatata
     5581 atccaaaagc taattcatca tttaaagcaa acacaccagt tgcagcagaa tcaagaagtt
     5641 ctgctgtgat ttggtagcca ccttgttttg agaactgtgt aggtaagagg atcagttggt
     5701 cgtgagagat ttggtaaaca tcaagagcag atttaaaccc ctcaatccga gcgtggacat
     5761 tttccggcgg attttcagga tagacaaggg cgatcgtttg atgacctaga ctaagcaagt
     5821 gcatgcccgc taggtaacca ccgcgaaaat cgtctgttcg tacggcatca ctaaatcctt
     5881 cagatttttt ctgatccaaa acaatgaagg gccggccttg ttttttcaaa ttttcgttga
     5941 ttgcatctgt agagacagca gaagtcgcga taatgaatcc atccacacct cgacgtgtga
     6001 gctcggctag atattcgatt tctttttgat gatcagaatc agcattacat aatatcgtga
     6061 cgaaattctg cttatacaag atatcctcaa ttcctcgcat cagtgtactg aagaatggat
     6121 tcgtgatatc aggaacgagt acaccaattg ttttcgtttc cttggtaatc atttgtctag
     6181 caaaatagtc aggctgatag cctaattctt ctttggcagc taaaactttc tgaacagttt
     6241 tcggactgaa tttctccgta tttccattta atatcaagga gacagttgtg attgaaacgc
     6301 cggaaagttt agcgacttct ttgattgtga tctttttttt caccatgttc atactcctat
     6361 ctaaatcctg tggttatttt cccatgaaat caaaaagaag taaatgaaaa tcacgtgtgc
     6421 cagtacttat ttgctttgtt ggatagcttc gattatttgt ttcgttgagc gtactcgtgc
     6481 agttttcgga aatatctttt ttatgaacaa ttgatgggat tctttgtcac gatcactgca
     6541 agcatcttca gcaagtacaa catgataccc atgttggaag gcatctaatg cagtagcata
     6601 tacaccgttt gttgtcgcta caccgcttaa aacgatagtt tcgattccac gccggcgaag
     6661 ttgaagatca agagaagtac caaaaaaggc acttggattg tattttgtga tagtcaacat
     6721 attgtttgta tctttcaagg aatccttcaa caacaagtca gtgaattctg ccggagcaga
     6781 caaagcagat attcctccag catctgtctg atgacttaga taagagaaag tagtgatgtc
     6841 tacattcact aaaactttca aggcagcggt acgtttcaat gtttttgcta acaaatcatt
     6901 gtttgtcaga atagattgtg cagtgtgtgg agagagtgta ccgttattta cgatcccttt
     6961 ttgcatgtcg atcgcgacaa aagcagtttt tgataaatca aaaatcatat tttcctttaa
     7021 atcattcatg atgttccttc tttcaaataa caatgttttt tatgtaagta aatcataaat
     7081 cgtttatttg tcaactaaat aaaggattcc tttctttagt ctagagaaat tcagtggtaa
     7141 aataaataag tatgagaaaa cgcattcgat gcatagatat agcgagaaat atcgtgaaaa
     7201 tggaggaatc agagtgaagt atgtcgaagt aaaaaatgaa tacaaacgat acaaaatggg
     7261 agaaacgacc attacagcaa atgacgatat ttctttttca attgaaaaag gcgaattagt
     7321 gattatactt ggtccaagtg gagcaggaaa gtcaacgatt cttaatattt taggtgggat
     7381 ggatacacct gatgaaggtc agatcattat tgatgacaca gatattgcgc aattttcaga
     7441 taaacagctt actgcttacc gacgaacaga tgtagggttc gttttccaat tctacaatct
     7501 cgttcctaat ctaacagcaa aagaaaatgt ggaattggca acggaagttt ctcctgatgc
     7561 gcttgatcct gtagaggtat tgaggcaagt gggcctagct catcgattga ataactttcc
     7621 gtcccaatta tcaggaggcg aacagcagag ggtttcaatt gctcgtgcac tagctaaaaa
     7681 tcccaaactt cttttatgtg atgaaccgac aggcgcgctg gattttgaaa cgggcaagca
     7741 agtattgaaa ttattgcaaa acgctagcag acaacacggc aataccgttt tgatcattac
     7801 acataattct gctttagcgc ccatcgctga tagagtcatt cacattaatg atgctaaagt
     7861 aaggtctgtt gaattaaatg atcatccttc atccattgat gagattgtat ggtaggggga
     7921 ttttatgaaa acaagaacat atcttaaagc aggttttcgc gaaattcggc aatctaaagg
     7981 acgattcatt gcaatcatcc ttattgtcat gctaggaaca cttttatttg taggtgtcaa
     8041 aactgctgga cctgtcatgc aaaaaacgat ggaccactat gttggtacag caggactttc
     8101 tgatttgcaa atcgtttcta ctggtggctt gacacaaaaa gatattgctc aagcagaaaa
     8161 gatcccagat gcaaaagtag aaacaggaaa acagatctat tattccaata ctggtaaaaa
     8221 cgaagtgatt caaatatttt cttataacaa aaataacaag cagaacaagc tacaattaac
     8281 tgatggaaaa ctcccggaaa aaccaaacca gcttgtattg gatgaaaaag cggaagatga
     8341 agggtataaa atcggtgata tttatcagat tgattcagat gaattgaaag aaaaagagta
     8401 taccatcacg ggctttgtcc gttctccatt gttcatcaac aatttggaga gaggatacgc
     8461 gaacgtcgga aatggtagcg tcgattattt tgtctattta cctgaatccg tttttaaaac
     8521 agatatttat tctgtcttat atcttgattt tacaaacgta aagaatttga atacgtacag
     8581 caaagcttac aaagataaaa tggaacacaa tcaagagaag gcagaaaagt atttacaaga
     8641 tcgccctgaa gaacgcttag aagagctgaa aaaatcggca aacgaagaat tagaaccagc
     8701 acagcaaaaa ataacagaag gcaaagcaca aatagcacag ggaagaacac agttagaaga
     8761 tgctaaaaaa caattagcgc aacagtcagc agctatccag cagcttcctg aagcgcaacg
     8821 aacaatcgct gttcaaacat tatctcaaca agaagctcaa cttgctgaac aagaaaggca
     8881 attagttgag aaagaacgtg aactggcctc tgcagaggaa gaattgaatc gaaatgcaga
     8941 aaaaattgaa aatttaacta aaccatcata cctatacaat gaacgttcag aaaatgtcgg
     9001 ttttcaagaa tttggtgatc tgtctgatcg tatcgctgcg attgccaatg tttttcctgt
     9061 tttctttttc tttattgccg cattgatcac ctttacgaca atgacacgta tggtagaaga
     9121 aaaccgcagg gaaatcggga cattaaaggc gttaggttat acgaaagttg aaatcgcaaa
     9181 aaaatatgca atctatgcaa gtctagcctc agggataggc attgttttag gaacgatatt
     9241 aggaacgaat cttttgccaa ggatcatttt tgagctgtct aacgagcggt atgatattgg
     9301 gagtgcgctt attttttatg actggccgcc gattttacaa gcagctgccg cattcttcat
     9361 tgccgcattt ggcgctgcaa tgatcgtttt attcaaagat ttaagagaac ggcctgctgc
     9421 attgcttcaa ccgaaagcac cgaagccagg gaaacgcatt tttcttgaat acatcactcc
     9481 gctgtggtca cgccttagct ttaatcaaaa aatcagttac cgaaatctct tccgatataa
     9541 gtcaagaatg cttatggcga ttatcggaat tgctggatgt gccgggctga tggttgcagg
     9601 cgtgggattg aaagattctc taagttctgt ctcagctaaa caatttggac cgatcattga
     9661 ctatcaagca atcgttacat tggattcatc cacggaagat agtcgtcaaa aagcagcgga
     9721 tatgctgcag aagcaagaaa aagtaaatga gatcctagct attcatactc aaaccgtaga
     9781 attgagaaaa aaaggacatg cttcgcaaag tctgacagtg atcgtaccaa gtaaaacagc
     9841 tgatttggat cgttttatcc atttaactga tcttgaagag aacccacgct ccttgcctaa
     9901 aacaggaatc gctattacgc aaaaagcagc agaactattt gacttatcta caggagatca
     9961 tatttcgctt tatgatgaag atcaaaaaga atggaaagtc gaagtaaaag aaatcgtgaa
    10021 aaactatcta ggtagcttta tttatatgtc ccctgaatat tatgcttcag ttactgatca
    10081 atcgatgatg gataatgcat ttttgctgcg tacagataag atgacaacaa aagaagaaga
    10141 aatgctttcc gagaaactgc ttgccacaga cgctgtgaca aatacgtctt tcatgtccaa
    10201 acaaatcgaa acgcaagaag aatcaatggc gaacttagac tcggttgtct taatctttgt
    10261 cgtattatca ggactgctgg cttttatcgt cttgtataat ctaactaata tcaatatttc
    10321 cgagcgtgta cgcgaattat ctacaataaa agtccttgga ttttttgata aagaagtcac
    10381 gatgtacatt gttcgagaaa atatcatctt tactctttta ggaatcatcg gaggatttgg
    10441 tgtaggatat atattgactg acttcatctt gcaacaagcg tctatggaga atgtcatctt
    10501 tccattagtg atcacatggt ggtcttatgt cttatcagca ggattaacta tcgtatttac
    10561 ggttattgtg atgattgtta cccatttcaa attaaagcat atcgatatga ttgatgcgtt
    10621 gaaatcgaat gaataaaaac agaggttgtg aaatcagcgt tttgagctaa taacgagggt
    10681 cagctgctaa ttgaacaccg tgaatcagag gttgtgaaaa agctgtcctg catcgagcaa
    10741 aaggaatact caaataaaat tagctcctca tgttttacat ttgagaagac tgattgccgt
    10801 agataaaagc ttttgagcac catttataga agaaacaaga atattttgct attttaaaca
    10861 agaggataga caaatacatg tctgatctct tgttttttat tgggcaacag acctcttaga
    10921 atgtataaag ataaatttta caaacgcttt ctgttcagtt ataataataa atgataactt
    10981 gtatatataa gttgcggtag gtaataaatc agttgaatgg aggtaaatat ccatgacatt
    11041 taaagacaaa gtcatttacc aaatctatcc caaatcttac aaagacagta atggtgatgg
    11101 aattggagat ttaaaaggaa tcaaagaaaa actcccgtat ctgaatgatc taggcatcga
    11161 catgatttgg ctaaacccta tttatccaag ccctcaaaaa gacaacggtt atgatatctc
    11221 tgattacaca gccatcgatc ctatctttgg tacgatggag gaattcgaac agctaatagc
    11281 cgaagcaaag aaataccgga tagaaatcat gctcgatatg gtgctgaatc acgtttcgac
    11341 agaacatgaa tggttcaaaa aagcactagc aggggaccag cattatcagg acttcttcat
    11401 tttaagagaa gagccaacgg attgggtatc aaaatttggt ggaagtgctt ggtcgccatt
    11461 tggagatacg gggaaatatt atttgcactt atatgatcgg acacaagctg acttgaactg
    11521 gcggaaccaa gcagtaagag aggaactatt caaagttgtt cgtttttgga tggaaaaagg
    11581 ggtaaaagga ttccgtttcg atgttatcaa tgttatcggt aaagacgaac aattgaaaaa
    11641 taacaaagaa aatgatggca aacctgaata tacggacaaa ccaatcaccc atacgtatct
    11701 aaaagaattg aaccaagcaa cgtttgggac ggattccact atcatcacag tcggtgaaat
    11761 gagctctacg acgatcgaaa attgtatctt gtatacagaa cctagtagag aagaattatc
    11821 aatggtcttt aatttccatc atttgaaagt cgattatgaa aatgggaata aatggtctac
    11881 tcctccattt gattttgcag aattaaagcg actatttcat acatggggag aaaagatgag
    11941 tgagggtaac ggctggaatg ctctattttt taataatcat gatcagccac gtgcgctcaa
    12001 tcgatttgta gctatcgatc agtatcgaaa acaaggagca gagatgctag caaccatgat
    12061 ccatttgaac cgtgggacgc cctatattta tatgggagaa gaaatcggca tgatcgaccc
    12121 agactattca tcgatttccg actatattga cgtagaaagt ttgaatgctt ataagttact
    12181 ccttgaacaa ggattcacag aaaaagaagc gtttcgtcgg atcaaagcaa aatctcgcga
    12241 taactctcga acacccatgc aatggtcaga cacagaacaa gcaggattta ctacagggaa
    12301 accttggtta aaagttggag gcaagctaga agagattaat gtagaaaaag aactatcttc
    12361 tgaagattct attttgtcct attacaagaa attgattcgg ctgagaaaaa catatccaat
    12421 cgttgcacaa ggagattatc atgcttatga agcaaatcat ccggaagttt atggctttct
    12481 tcgccaattt gaaggacagc agctgcttgt attaacaaat ttctatgata aagatacaag
    12541 gatcaccatc ccagaaggat tcacagaagc caatattctt atcgataatt attccgatac
    12601 tgttcttcat caaagtctgg agctaaaacc ataccaggca attgctttgc tgaaaaatta
    12661 aaacaaaaac acaaaacgtc gttcctacga gctattctcg taagatcgac gttttgtgtt
    12721 ttatttaaaa taatcttctt cagaaaatga agagttttca tactctcctt tatcgccata
    12781 aaatttattg tagcgttgtt tgaatttacg gaaaataaaa gtaacgagta atttgactaa
    12841 cgtatagata ggaataccaa aaataacgcc cacaattccc attagatcac ccatgacaag
    12901 taaaacgatt aagatcgtaa tcggatggat ctgtaaacga tcacccatta ctcgaggaat
    12961 caccaagtca ccgtggagaa gttgtacggc aaaccagaca atgacaaatt tgacagccat
    13021 aaaagtagag tcttggaatg caatgatcaa acctggaaag aaggcgataa acggcccaat
    13081 atatggaatg atacataaca acccagcaga aatagctaaa acactagcaa attctaatcc
    13141 gatcagtaag aaacaaaccc agtagactgc tccaaggata aatgaagcaa tgatttgccc
    13201 ctttagaaat gaacccaatt gttgattagc aatctttgtc aaatttttaa aatctgtacg
    13261 aaatgctggt gggacaatcg ctaaaactga ctgataaaat ttttgaggat ctctcaaaag
    13321 aaaaaaagcg acaattggac cagtaaataa agtaataaaa atagctgtaa cagttgaaaa
    13381 aatgttgctg atccgttgtg cgccactttc ccaataattt ccaataaatc cagctatatc
    13441 agacgtcacg tcgtcaatag aagcgaaaaa ttgattaaat gaatcggcaa aaggtgtttt
    13501 ctctaaaaat tgtcggagac tctcttgaaa atcttgaaac aaatctggca aactactgat
    13561 caatgtcttt gcctgttctt caagaaaagg aacaagccat acgcttccaa gccccaataa
    13621 aaataaaata atcacataaa cgataatgac tgacaagttc ctcgaaaggt gcttgctcaa
    13681 acgtttgatg actggttcca aaagataata caagatcagt gcaaacaata atgggggcaa
    13741 gatagtagcg ataatgattc cgacaggctt gaatataaac gagatctgat ggaaaaaata
    13801 aatgatcagc gcaagtaaga taactattcc taaaacatag taagaggttt ttcctcctaa
    13861 aaagcggatc aaacgattcg ttgtatctgt ttcttttttc actctttttc ctcctttatc
    13921 tataacttca ttatagacaa aagcgggtat aaaaggaaaa tgatagaggt tgattgcaaa
    13981 aatatcgtca atcattcata taaactttct catcaattaa aataagaaaa cgcttgacag
    14041 ttcttttaac catatgataa attaaatcct gttgctaaaa cgtaactatt acgttttgta
    14101 aaaggcgaat cggaacattc aaatgaaaga agatgagaag aggagtgtca taaatgaaac
    14161 gattgatagg tatattggcc atgctggttt tagcaggtat gttaactgct tgcggcgggg
    14221 caagtgggaa agccgaggac agtaaagaaa aattgagcgt gatgacgacc ttttatccta
    14281 tgtatgattt tacaaaagca atcgtcgggg atgaaggaga agtagagtta ttgattccag
    14341 cagggactga ttcccacgat tatgaacctt ctgctaaaga catggcaaag atccaagata
    14401 cagatatctt tgtttataat gatgaaaaca tggaaacatg ggtccccgca atccaaaaaa
    14461 cattacaaga aggcaatgtc catacgataa aagcgacaga aggtatgctt ttacttccgg
    14521 gaagtgaaga aggacatgat catgaccatg aacacgggga agaaggccat acacatgagc
    14581 tagacccaca tgtatggcta gctccaagtt tagcaatcaa gcaggtagca aacatacgtg
    14641 atcagctgat tgaagcttac ccagaaaaac aggaagtatg gacaaaaaat gcagcagcct
    14701 ataccgagaa acttcaagca ctccatcagc tttatcaaga aacctttaag caagcaaaac
    14761 aaagatcttt tgtcacgcaa catgctgcat tcaactatct ggcattagaa tatggattga
    14821 atcaagtatc gattgctggt ctttcttcta gtgaagaacc gtctgcggcg agaattgctg
    14881 aactgaaaca ctttgttaaa gaacatggaa tcaactatat ttattttgaa gaaaacgcca
    14941 aagatagtat tgccagaacg ttagcaaacg aagcaggtgt atctttagaa gtattgaatc
    15001 ctttggaagg attgacgaat gaacaaatag aaaatggaga aaactatctt tctatcatgg
    15061 aagcaaacct cgaagcgttg aaaaaaacga cagagacaga aaacccgcta gaagatactt
    15121 tgacccccaa aaaagaaaag agcgtctaca acggttattt tgaagacgag gatgtacaag
    15181 atcgctctct ttcagattgg gcaggaactt ggcaaacagt agatacgtat gtagaagatg
    15241 ggacttttgc tcctgttttt gaatataaag aaaaattgaa tcaggataag acagcacaag
    15301 aatataaaga atattatacg aagggctatc aaacagatat tgcttcaatc aagatcagtg
    15361 agaaagagat ggcatttacg tttaaggatg gaacaacgaa acgttcaaat tatcgttatg
    15421 tagggaaaga aatcttgacc tacgaggcag gaaaccgtgg cgtaaggtat ctattcgaag
    15481 cagaagataa ggaaagtggc gcttttagat atattcaatt ccgtgatcac acgattgcac
    15541 cggctgactc cgaacatttt catttatatg caggaaatga aagtcaagaa gcattgctga
    15601 aagaaatgga gaattggcca acattttatc cagatacaat ggatggacgt gaaattgcac
    15661 aggaaatgct tttgcactga taggcaaaaa agaaccgaag ggtttggatc ggctagtcat
    15721 ttagtcggtc caaactattc ggttcttttt atgaaatcaa tttctttaat ccacggatag
    15781 aggctgggat ggtctcgccg tttgccaacg tgacttctct ggttttttta ttaatcgacc
    15841 gcacattttg tgtattgata acataggatt tatgacaacg gataaaattc cgatgcattt
    15901 tctcgatttc tttgatcttc tcatagaatt gtaattgggc atgagtcaaa tggacttcca
    15961 gtttatgtgg tgctcctagc gaagtagaaa aatattggat gtctttgatc ggtaaaaatt
    16021 tgatctcatc attaaactct attttgaaga tatctttttg gatctgggac atttgaaaat
    16081 cttcgaaaat tttgctcagg atatgctcga cattttcttt taaatcataa agatcttctt
    16141 tgacgatata atcagtcggt tcgatgttgc tttttaagat tttcatcgac atttccgtat
    16201 gggaagtcac atagattatt tttcctaagg gatctaattc acggatcaat ttaccgatcg
    16261 ctacaccatc catttcactg tcttctagtt cgatatctaa aaagtaaata ccaaaagaag
    16321 aagttctgat cttggctgca ttgagaagtt cttccggatc agaggtagaa atatggacat
    16381 aactgtctaa gttttcaatc atgattctat ttttgatcac cgttgataaa acttctaatt
    16441 gttttggatc gtcttcacaa atataaatgg gaatcatatc attactcctt tattttattt
    16501 gtatataaat cgtttgagaa aaacgctggt tttcaattga tgtttcaagg aaaagataag
    16561 gattggtctt tgtcaattca tccaagataa acaagccaag gccttcgttt tttggatttg
    16621 tttttgttga gaaccctttt tgtttcaact ggtttaacgg caatgtattt gttgttgtat
    16681 tgatcacacg aatcatcacg gaatgattct tcttgagtat ggtcaattcg atttttttct
    16741 tctttgcagc actagctcct tcaatcgcat tgtccaagat aataccaagc atacgtacaa
    16801 ggtttaccgt atgtttcgta tccagttcga ttggctcagg aaaatgaagc tggacgacca
    16861 accctttttc ctgtgccatc atgagtttta atgacagtaa actacggatc tcaggaactt
    16921 tcatattatc caacatactt agattggccg gaaaaaggtt catcatctgg cgtgtaggta
    16981 atatcgtttg agcataataa gaccgtaatc cttctaagtc gccttctgaa atatagctgt
    17041 gaagagaaaa aagcagattt tggtaatcat gtttgaattc tctcaagtct tgatagtttt
    17101 tttctagatc tttgatataa tcctgttgca tcctgacttg ttgctctaat aactgatcag
    17161 ctaatttctt attagagatt ttccaataat aaaccaagat gatcaggcca acacacagat
    17221 atagaatgaa aaaactcgta ttcaaagcta agacatcagg tgtttcacca gaaaaacggg
    17281 tataaaaaat aatgatatag tatgtaaata atatcaatgt cccgatcgta ccgatcatac
    17341 ggcggtccac agtgtgaaac caagtctcta acgatttttt aaaacaaaaa gctaataaag
    17401 cagataaaaa agcggataag gcaatgtgaa aatactgcaa tgaatctcct ggttcaataa
    17461 ccgaagattt caaaacaaaa aaatcgccga tgcttgttaa gtgatctcct aaaagcgacg
    17521 tcaataaccc aaaaggaagc gcgtaaacca attgttgacg cgaagtcgaa aagaagaaaa
    17581 aagtaagcat cagcattcct atagcaatta gagcagtaaa aatccctaaa atcgaataga
    17641 cccatccaat caaaatacaa gaaatcagaa tgactcccgc aaacagatat ttgtatcgga
    17701 tgtgatggtc aatcaataag atacaaattg tgtaaatcaa atattgcaac gctatggacc
    17761 ataaaaacat aaagtacagc tcccattgat ttttaccaaa ttatagcaca attagcgtat
    17821 tattttttta atttttcagg gattttgaat tcagaactca taccaaagca gcagccagat
    17881 acaaaaaagt cagataagtt agttaattgt ttaatgattg tttttttcat gaaagattcc
    17941 tccaaaattc atcaagtagt ttgtaatagg aagcaacgta gctatttcta aaacaatccc
    18001 aagtagcaaa taggtagaaa agtaagaagc tgagaaaaat aaagtaatga gagaaaaaat
    18061 tagaaacatg ctgatcgcct tctttaataa tgggggacgt ttctcgggtt caatgggatt
    18121 gattgctgta cctcttgatc catagcgaag cagtaacaaa aagcagctga ttaacaaaaa
    18181 gaccatcatt gggaaggaga tagtcaattg cagatgtttc atcaccaagg gaacgcccca
    18241 taaataaagt agtgtccaca gcagacaaac gaattcagag tcggaatgca atccataagc
    18301 atatctgcgg atgcatatat aagaaagaaa ggtgattcct gtttccgccc atgagcctgt
    18361 caccagagaa aagactagaa cgaccgctag ttttccaaga ttattcaata aaacttctaa
    18421 ggcaaatttt acttggacat acaccatatc ttcttccgat ttgtctccgc tgaataaggc
    18481 ttctaataat ttgttcacaa ctttatcttt catctcatac gtacctctac cacaaatttt
    18541 atgctaaaaa aaataaaaaa cgtcttttgt ttcataaaaa gtggttttga catcaaaacc
    18601 gtcatgattt cctaaaaaaa tcttcgtttt ccaagaacct taccaaaaaa agtgacagtt
    18661 ttgatacgaa aagtactttt tatgacaagt ttgtgctttt tcgagtgatt tatgttaaaa
    18721 aaattactga ccttataaaa ggtgatggag ggattcttat ggaaaatgaa caattgtttg
    18781 aagtcggcga aacatatgca tttaaatctg atttatttga atcaccaata aaaggaaaaa
    18841 tagaaaaaat ctatgaaaat agtgtgatga tacgtgtcat gaaatgcgca gtagaagaca
    18901 atgataccgc tcataatctg cactggcagt tagttgtacg caaatcaagt acaatagaag
    18961 aataaaaaca gataaaatgt tgagagcata aagaggttgt gagtctccgt ttagctctga
    19021 gttacaagga ataatgttaa aaaacagctt ttcatgtttt atgaatattg ccacttgtga
    19081 ccgaggtgtt ggcaggagaa tactgtttat ttgaaaaaag ggctgcgaca agacttttgt
    19141 cacagccttt attttcatga ataggagtta cttttggcta cttttagaga agtagctttt
    19201 aaggagcaga taaagtcaag gcttttattt ctataaatga agtagtaaaa tgaagaacag
    19261 attttattac aggaaggatg ccgataattg tgatcattgt tgcaggaacg atcggtgcag
    19321 ggaaaagcac actgactgaa atgcttgccc aagatttaga aacaaaacct ttttatgaga
    19381 acgtggaaga taatgaagta ttgccgctat tttattctaa tccagaaaag tatacttttt
    19441 tattacagat tttctttttg aacaaacgct ttttggcaat caaagatgct ttcagccatg
    19501 atgacaatgt actagaccgc tccatctacg aagatagtat gctgtttcat ttgaatgcag
    19561 atttagggcg tgtttctgaa gtagaagtaa agcagtatga aggtctttta gaaacgatgc
    19621 tgaaggagtt agaagaaatt tcgccacaaa agaaaccaga tctactggtt tatattcgtg
    19681 tatcttttga aactatgtta gcgagaatca aaaaaagagg ccgggaatat gaacagctag
    19741 aacaagatcc tgaactctat tcctactata aagaactcaa tcgacgatac gaagagtggt
    19801 atgaacagtt tgatatatgt cccaaaatag tgatcgatgg ggacaaatat gatttcgtag
    19861 ccgatccggc atgtggagaa caaatcgtac aagaaatcaa gatgcgggca aagaaaatga
    19921 cagaagaggc agatgcccag tcgatccgct acactacaaa taacccgaaa gcaaagggaa
    19981 tctttacaac taaataatat aaaaactaag caaattgctc actcgcagat atttctctgt
    20041 gagcagcatc ttgcttagtt tttttgattc attgagatca aatagtgaac cgattcgtat
    20101 gataaaattg ccataaatga aatgtctgag tgagggccat gatcaaaaat aaaatggaaa
    20161 cgatcaaaat cgaatgggcg ccaaacagat gatgacagaa aacaaggaca atagctcctg
    20221 cgataaaggc aagaacgaca cttagatagt ggaaaaatcg atcaaaatct gctttttctt
    20281 tagaaataca ataatcatat aagttcgttg ctaccccttt taaatttcca gttgtaaata
    20341 aattagtgta ggcacgcccg ttgattttat caaaagctac ccactggatc gatgcagtaa
    20401 aagcaatcaa aatcgttact aatgcgggat gctcatggac gggtgtcaaa ctaacaaaga
    20461 aaaaaatcac tgcttcataa tatagaacaa acaagcgcca gaaatgtttt tctttttttc
    20521 taaaataatc aattagatac tttgttagaa gaatccctaa gaaaaagaaa agggtagaca
    20581 atactttttt accaacactt agccattctc cgtcaaatgc ttggatgatc gatagaatga
    20641 tattgccagt ttgagcagag gcaaaagcac catattggat ataagtataa ctgtccatgg
    20701 ctcctccgat aaatgtcagc aaaagtccta ttgtacgccc ctcgtgaaag gaagtctgca
    20761 tttttttcat caccttttat gaatattttt gtcttcctta tcttagcata aacgattgaa
    20821 aaaaaggaaa aattttcaga aaactaaaat catatcgctt cccattttca tttttagaaa
    20881 ggtctgttag tataaagaaa aaatagacaa cgaaacttta aataaccaac ttgaaataac
    20941 caacttgaaa taaacaaatt caaagaagaa agatgggaag gaaatcaatc agttgaatga
    21001 aaaagaaatt ctccgattac aaaaagaatt gaaacgctgg gagaacaagt ataaaaagct
    21061 tcaacaagtc tttcggctac aagaagaaat cattgctacc tatgaagcgg cttatggcga
    21121 agcacccgga cttattgagg aagaagtaca agtaaaagaa agtgaaggaa acagctcttt
    21181 ctttaaaatg atggagaaac gttcctataa tcgcttcaat caagaacaaa aagcagctat
    21241 cacatatgat atgaagaaac atcttcgaat catagcagga gctgggagcg gcaaaacgca
    21301 aacaatctgt gcaaaagctg tttatctgat gacgcaaaaa caagtagacg aagaacgcat
    21361 actaatgatc acttttacaa ggaacgctgc aaatgaacta aaaaaacgag tagataattt
    21421 cagccagaga aaaaccgctg tccatatcgg aacattccat agtatctttt ttaggatata
    21481 caatgaaatt tgtcgaaaat ttcctgaagt agcaatgcaa ggaatacaag gagacttttc
    21541 aaaggatact gcacaaaaag tgaatgctgt tttgcaacag ctgatacgta aatataatct
    21601 ttatatattt gatcaatatg gagaaaaaac gattgcttct cggttagact attggcagaa
    21661 tatgaacctt tcagtagaag aaatggttca gttagttaaa gaaaaatatg attccattga
    21721 taagaatgca cgacagccga tatcagaacg actgtatgga ttgctcacgg aactccaaga
    21781 acaaaaaaga agccagcaat tgctagagtt caatgatgta ctccaaaatc tgaaaagcgc
    21841 tttggagaat gaggagatcc agcattatat cggccaaaaa tatgattatc tattcattga
    21901 tgaatttcaa gatactaatc cacttcaatg ggaaatcgtg aaacggatga caaaggaaaa
    21961 caggatcaag ttgattgttg ttggagatga tgatcagagt atctatggat tcagaggatc
    22021 agagccagca tacatcaaga actttgaaaa agaatatcct accaaaactc ttttcttatt
    22081 aactaattat cgttctcggg cagctattgt ccaaggagca aatagattga tcagctataa
    22141 taaaaatgat cggataccaa aggcgatgat tccagcacaa aaagaagcag gtgttatgga
    22201 agcctatttg ttttctgata ctaaagcaga aagtcagtgg ctaatcaaac aaattcagac
    22261 atttattcaa aaaaatggga aatataagga atcaatcata ttataccgat cagcttcaca
    22321 aacgcagcag cttgtccaat ctctgctgaa aacgaatatt ccttttgtac tggaagcaga
    22381 tagtccatat gaaggtatct ttggtatcaa gtctttccaa catttctatc aaaaaattgt
    22441 tcattggcaa acagcactga atctgcaaaa gaaaaatcag gcctaccagc aattgctccg
    22501 gcagctgatg gcagactgct acctgaaaaa aagtgaatgc gatcaatact tttctcctaa
    22561 atatcaaaat atagccgttg cagattatat tttgtcgata agccccaatt taaaatcaaa
    22621 atctgcagaa atccgagagt ttgaggaagc gttgcgtaaa acagaccagc atcaagaaat
    22681 ctattcgctt gttcaaagct atcttcatct gccacgtata gctaaggaaa tcgaccagag
    22741 tgatcaagaa tggatacgag aagaagtaaa gcagcatgct actttcagaa gactccaagc
    22801 cttatcgcaa gaaacccaag cgacagctaa agaattaaaa acccgcttga ttgcttacag
    22861 acaaggaaaa cttgatgcac tatgtatcca gagcattcac aaaagtaaag gtcttagtta
    22921 ccgaaatgtc tttttgattg gttgtaacga aggaagtttg ccttataacg gagcgacaga
    22981 aaagaaagta atcgacttta atgaaataaa agcagaacca gtgacgacga tagaagaaga
    23041 acgaagacta ttttatgttg cgatgactag agcaagaaat cgtctgtatc tatgtgtacc
    23101 tcaaatgaaa aattcaagaa aattgaaagt atcgagattt atcaaagaaa ccgggagtcg
    23161 tgtgaaaaaa ggaaagtgat agaagagagg gtgtgacaga agtggtcagt ttcaagaaag
    23221 aagaaggaat gtacgaaaat tgcttctcaa atttttgtga aatttcagct tattttcgaa
    23281 gaagctattt ctggaacacc gtttattcgg aaaaaggagg tgtgacaaga attttgtcac
    23341 acctccctta tttattttga aaatgagaat actattatca aaatagagaa tatatagaat
    23401 aattctcatt attcaaacgt aaataatcag tt
//
LOCUS       DACDLM010000046        23376 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.046, whole genome shotgun sequence.
ACCESSION   DACDLM010000046 DACDLM010000000
VERSION     DACDLM010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23376
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.046"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..2270)
                     /locus_tag="IV356_001809"
     CDS             complement(<1..2270)
                     /locus_tag="IV356_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP9015497.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEK"
     gene            2548..4371
                     /gene="cadA"
                     /locus_tag="IV356_001810"
     CDS             2548..4371
                     /gene="cadA"
                     /locus_tag="IV356_001810"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAP9015498.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            4418..4597
                     /locus_tag="IV356_001811"
     CDS             4418..4597
                     /locus_tag="IV356_001811"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HAP9015499.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            4934..6874
                     /gene="thrS"
                     /locus_tag="IV356_001812"
     CDS             4934..6874
                     /gene="thrS"
                     /locus_tag="IV356_001812"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HAP9015500.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            7098..7946
                     /locus_tag="IV356_001813"
     CDS             7098..7946
                     /locus_tag="IV356_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP9015501.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            8341..10494
                     /locus_tag="IV356_001814"
     CDS             8341..10494
                     /locus_tag="IV356_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HAP9015502.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(10680..11489)
                     /locus_tag="IV356_001815"
     CDS             complement(10680..11489)
                     /locus_tag="IV356_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP9015503.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
     gene            11782..13218
                     /locus_tag="IV356_001816"
     CDS             11782..13218
                     /locus_tag="IV356_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAP9015504.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            13388..14584
                     /locus_tag="IV356_001817"
     CDS             13388..14584
                     /locus_tag="IV356_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAP9015505.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(14646..14831)
                     /locus_tag="IV356_001818"
     CDS             complement(14646..14831)
                     /locus_tag="IV356_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HAP9015506.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            15062..18376
                     /gene="dnaE"
                     /locus_tag="IV356_001819"
     CDS             15062..18376
                     /gene="dnaE"
                     /locus_tag="IV356_001819"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HAP9015507.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            18543..19505
                     /gene="pfkA"
                     /locus_tag="IV356_001820"
     CDS             18543..19505
                     /gene="pfkA"
                     /locus_tag="IV356_001820"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HAP9015508.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            19579..21363
                     /gene="pyk"
                     /locus_tag="IV356_001821"
     CDS             19579..21363
                     /gene="pyk"
                     /locus_tag="IV356_001821"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HAP9015509.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(21398..22300)
                     /locus_tag="IV356_001822"
     CDS             complement(21398..22300)
                     /locus_tag="IV356_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP9015510.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            22486..23055
                     /locus_tag="IV356_001823"
     CDS             22486..23055
                     /locus_tag="IV356_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HAP9015511.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            23113..23292
                     /gene="rpmF"
                     /locus_tag="IV356_001824"
     CDS             23113..23292
                     /gene="rpmF"
                     /locus_tag="IV356_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAP9015512.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
BASE COUNT         7437 a         4140 c         4950 g         6849 t
ORIGIN      
        1 tttttctcat aagatgaaat atccatattg tttaacaaag gactttcatt attggaggta
       61 aaaagggtca attcatgcat cgcacgtgta cacatggtgt aaaggatcaa tttgtcttgc
      121 tgagaagaaa aatgttctgc atctacatcc cacaagaaaa ctcggtcaaa ctccagacct
      181 tttgctaaaa aggctggaag taaaataatg gaacgcttca taaagtcact ctcatttaaa
      241 atcagctgga cttgttgttt caactcgtct ggcagttgag cataaagagc ttcgcattct
      301 tcttgtgttt tagctatgat tgctgtacgc caataccggg cttttccctg agtcgttcga
      361 atggtatctg ctaaccaatt caatttgata tcatctgttg ttccttggat gagcaaagga
      421 aggtctcctt ttcttgctgt tgtttctact tgatgttctt tcacaataaa atgattagca
      481 aaatcagtga tttcttttgt ggagcgatag cttgtcgtta attggaaacg agtgacttca
      541 cggtccacga aaaggtcttc caatgatcca acgatcgttt catttccaaa gacattttga
      601 tttagatctc cacagaaagt caaatttgct tttgggaaca aggcttgcag caatgccact
      661 tgtgatggtg cgaaatcctg catttcatca ataaagatat agcgagcttt gtgtgtaacc
      721 gtcactggat atgttcggcg catcagtaaa aagaatagta cagcatcctc ttgacgcaat
      781 tctctttgac gcaagtgtgt acgaacagtt gtcaaatgtt cctgccacct ggtctcgctg
      841 attttatgtc gtgttagaag agaaagtggc acagtttgta gaaagtggag atattgtttc
      901 gttatattga caaattgata attcatgatc cctcgatgga ttcgacggaa tcttttacgt
      961 acgatttggt tggccagttt tttacgtaat gaacgctcct tttgttctgt atattcaaga
     1021 tttggatctg ttgcgtatag ttcttggagc tgttcttccg ccagatcttt gacccattgc
     1081 tgacgtgttt cgtctttttg cagaccgcct aattttttca ggagcttcgt ttgtaataga
     1141 gaaagtctat gatgtaaagg taattgttca tttgtttctt tataccattg gcgaatcgat
     1201 tcctttgata ggatcgtacg gccatttatt ttcatatcac ggaacaaggg accgtagttt
     1261 gtgatgcctt ggatatagcg atcaatctga tcgactaagg tcaatccgct tttcatcact
     1321 tgtatcggat ctttttcccc tagcaaaaaa ccactttctt gttgctgttc atctagtaaa
     1381 gaaaactctg gcagcagctg caccaaataa tttttgaatg tctgtgtagg cacgccgctt
     1441 tcacctaatg aaggcaatac agtcgagatg taatcagaaa acaaatggtt gggtgaaaat
     1501 agaagaacgt tttcagcctc gagccacttg cgattatgat acaacagaaa agcaatacgt
     1561 tgaagcaaag cggatgtctt tccacttccg gcgattcctt caatcagcat tactttactt
     1621 gttgtgtccc gaatgattgc attttgtgct ttttgtatcg tagagacgat gtttttcata
     1681 tggttgcttg atgattcatc caatatctct agcaaaaagt catcattgat tacttccgac
     1741 gtatctacca tagataaaat acgtccttct tggattttaa attgtcgttt caactgcaga
     1801 tcgacatcta ttctatctgt ttcagtttca taaaatgcgg gaccaatctc accttcataa
     1861 taaagattgg caattggtgc gcgccagtca ataacgattg tttcttctgc cagatctctt
     1921 aaagaagcga tacctagata taatgtttct gtttcacggt cttctttaaa gtcgatacgg
     1981 gcaaaataag gactatcttt catgacagac aacgtttgca ggcgtttttg ctgtgcttca
     2041 agagtatggt atttcaaaag caattcctgc tcatgttggc gatattcaac agcagattca
     2101 taaaaagctt cattggaacc agctcgaatc ttgtgattag ctgtgtcttt tgtcgaatga
     2161 ttcatttcct gagtcaattc ttgttgtttt gtatccagca tattttgttc gatctggatt
     2221 agttcgatcg tttcatccac gtgcgtttgt tctagttgtt tctcattcat cgcatgtttg
     2281 ctccttccgc cgtaaataac gaattaaaag tatagcatag tttttcgaaa aaaggtactt
     2341 tttaactgat gaatcgaaaa agtaatcctt gctgaatatt tttgtttgta gaactgatga
     2401 attttggaaa cgctgatagt gatagttgtt ttcaattaag gcctattgtt ttaaaaagtg
     2461 ctagtcaagg actatgctta agatgaaaga ggcagctgga aatttattac taacctctct
     2521 aagtcacata aaagaggaga aaaaacaatg acacatttca aaaaattttt acttactttg
     2581 cttattggtg ggatagcttt attaagtgaa tttgtttttc accagccggc ccttgcattt
     2641 gcgattgtcg catttactgg agggattctc gccttcttga tgtttttgga aatgatcaag
     2701 acgttacgtt caggaagata tggcgtagat gtattagcga ttaccgcaat ccttgcaaca
     2761 ttagccgtca aagaatactg ggctagtttg atgatattga tcatgcttac gggcggagat
     2821 agtctagagg attacgcgaa taaacgagcg ggtaaagaac tgcagtcttt gttagataac
     2881 accccaagaa ttgcccatcg attcaaagaa ggaaaattgc aggatatagt aatcgatgaa
     2941 ataaatattg atgaccagtt actagtcaag cctggcgaac ttgtacccgc agatggtcga
     3001 gtgaccaaag gagaatcttc ggtcgatgaa tcttctttga caggtgagtc ccgcccggaa
     3061 accaagaaac ctggagatca gattatgtca gggtctttaa atggagacgg atcgatccaa
     3121 atgatcgctg aaaaacgtgc cgcagacagc cagtatcaaa tgattattaa actagtcgaa
     3181 gaatcaaaag aaaagcctgc ccgatttgtc cgtttagctg atcgttatgc agtccctttc
     3241 acgttgattg cttatttgat cggtggtatt tcttggtggt tctcaaaaga ccctttacga
     3301 tttgctgagg tactggtagt ggcatcacct tgtccactga ttctagctgc gcccattgct
     3361 ttagttgcag gaatgagccg ttcaagtaaa aacgggatcg ttgtaaaaac tggaacaacg
     3421 attgaaaagc tcgcacgtac aaaaacgatt gcttttgata aaacaggaac gcttaccaaa
     3481 gggatattgg aagtagaggc gattcagcca gtcaatggaa taaaaaaaga agagctactt
     3541 ctgtatgcag ctagtgcaga acaggaatct agccatatct tagctcgttc gttagtgaac
     3601 aacgtgaaaa acagccaact gtatcctgtt agtcaactga aagaagtgac cggtcaagga
     3661 atccaagcag tagtcaataa tcatgaagta aagattggac gtgcctcttt tgtttcagct
     3721 gaagaaatag aaacgtccaa tacagcaatc tatgtaacaa ttgatcgatc ttttgcagga
     3781 acgatcctat tttcggatca gattcgccca gaagcagcaa agacaatcaa ggagctaaga
     3841 aaacttgatg tgaaaaattt gatgatgatc accggggatg gatctgccat tgctcaaacg
     3901 attgcagaaa aagtccaatt agattctgta catgcccgta gcttgcctca agataaactg
     3961 accattttag aaagtatccc taaagatcaa agacctgttg cgatggtagg agacggcgtg
     4021 aatgacgcac cagcacttgc tgctgcagat atcggtattg caatgggggc tcatggttct
     4081 acagctgcta gtgaaagtgc agatgcggtc atcttgaaag atgatctctt gcgtgtagca
     4141 aaagcagtag tgatttcaag agatacgatg agaatagcga aacagtctgt actgattggc
     4201 atctttattt gtattttttt gatgttaatt gcaagtacgg gactaatccc cgcattattc
     4261 ggagctgttt tgcaagaagt cgtggatacg gtctctattt tgagtgcctt gagagcaaaa
     4321 aaagatccag ccatttttcc tgattcagta cccaagacaa acatagtatg atagaatcga
     4381 gttgaaaaaa gaacgatcag aaagaggaga gagcattatg ccattcgtac atgtcgaatt
     4441 agtagaaggt cgcagtccgg aacaattaga aaatatgatg aaagatatca cggaagctgt
     4501 tcataaaaac acgcaggcac caaaagaaca catccatgtc atcatcaatg agatgaaaaa
     4561 aggaacatac ggtgtaaatg gggaatggaa aaaataagtt tagtttccca cttgattttt
     4621 ctatttatta gtggttaaat aaacacataa ttgattgatg agaaagccaa ctgaatttga
     4681 gagtcttcga taagagagga aaagctaggc tgaaactttt ccaggagaaa accaaaggat
     4741 gaccactttc gaaacccttg ttgaagcaag ggcggtcgga ccgttacaac gcttgaggaa
     4801 cgcatttgcg tttgaacatt aggtggaacc acgaactttt cgtcctagta tctcttttca
     4861 agagatgcta ggattttttt gtttttcagc ttgatgatct gatcaatcaa aacatttcaa
     4921 ggaggaaact attatgataa aaattacttt tccagatggt gcagtcaaag aatttgagtc
     4981 tggaacaaca acattggcaa ttgctgaaag catttcaaaa agcttagcaa aaaaagcttt
     5041 agctggtaaa gtgaacggaa aactcgttga tttgactcgt ccaatcgagg aagatgcaag
     5101 tattgagatc atcacaccag accatgaaga tgcacttggc ttagtccgtc attcagcagc
     5161 tcatttgatg gcccaagcca tgcgtcgcct ctatccaaat atccactttg gcgttggacc
     5221 agctatcgat tcagggtttt actacgatac agataatgga caaaaccaag taactgcaga
     5281 agatttgccg gcaatcgaag cagaaatgat gaaaatcgtc aaagaaaatc tgccgatcga
     5341 acgccgtgtt ctttcaaaac aggaagcatt agaaattttt gcaagtgatc cgtacaaagt
     5401 agaactgatt agtgaattgc cagaagaaga agtgattact gcttatcaac aaggcgaatt
     5461 catcgatttg tgtcgtggac cacatgttcc atccactggc cgtatacaag tatttaaatt
     5521 attatcagtg gcaggtgctt attggcgtgg aaactcaaac aatcaaatga tgcaacgtgt
     5581 atacgggaca gccttttttg acaagaaagc tttgaaagaa tatatccgtc tccgtgaaga
     5641 agcaaaagaa agagaccatc gtaaactagg aaaagaactt gacttgttca tggtttcccc
     5701 agaagtaggt tctggtttgc cattctggct tccaaaaggg gcaacaatcc gacgcacgat
     5761 cgaacgttat atcgtagaca aagaagttag tctaggttac caacatgtat atacaccaat
     5821 aatgggagat gttgagttgt acaaaacatc tggacactgg gatcattatc aagaagacat
     5881 gttcccgcca atggatatgg gagatggcga aatgcttgtt cttcgcccaa tgaactgccc
     5941 tcatcacatg atggtctaca aaaacacgat ccattcttat cgtgaattac caattcgtat
     6001 cgctgaatta ggaatgatgc atcgctatga aaaatcaggt gctttgtcag gtttacaacg
     6061 tgtacgagaa atgacgttga atgatggtca tacatttgtt cgtcctgatc aaatcaaaga
     6121 tgaatttaaa cgtacgcttg aattgatggt ggcagtatat gctgacttca atattacaga
     6181 ttatcgtttc cgcttgagct atcgcgatcc aaacaataca gataaatatt ttgatgatga
     6241 cgcaatgtgg gaaaaagccc aagcaatgct gaaagccgct atggatgaat tagaactaga
     6301 ttactttgaa gcagaaggcg aggcagcctt ttacggacca aaactagatg ttcaagtcaa
     6361 aacagctctt ggtacagaag aaacattatc aactatacaa ttagacttct tattgccaga
     6421 gcgctttgat ttgacatatg ttggagaaga cggggaaaat acgcatcgtc cagtagttat
     6481 ccaccgcgga attgtttcta caatggaacg ttttgtcgct tatttaacag aagtatacaa
     6541 aggcgctttt ccaacatggt tggcacctat acaagcaaca atcatccctg tttctgttga
     6601 tgcacatggc gattatgctt atgaaatcaa agaacgtttg caaatgaagg ggttgcgtgt
     6661 agaagttgat gatcgtaatg aaaaaatggg ctataagata cgtgcctctc aaacacaaaa
     6721 gatcccttac caattagttg ttggagacaa ggaattggaa gatgcaacag tgaacgtacg
     6781 tcgttatgga agtaaagaaa cagctgtaga agatttgaat atctttattg atgctatgga
     6841 agcagaagtc aaaaattaca gcagagaaaa ctaataggta aatttcctgt aaaaaagtag
     6901 tagatagaaa gcaatccgaa caatagataa caggtattcc tcaaagacac agatgctcaa
     6961 tagaatctgt gggattgatg ggataagata ttctgttggg cggattgttt ttttgttttt
     7021 tatccagtat acgaccgtga ataagggtct gatatggtat acttacatag actatcatta
     7081 aaagggtgga ggaacttatg agcgtaatta gtcgtattga aagtatgatg gaagattatt
     7141 cttcagcaga aaaaaagttg gccaactaca ttatcggtaa tattgagaag gtccctacaa
     7201 tgacagctaa tgaattagca gaagcttccg ggttgagtgc gccgacagtt gtacgttttt
     7261 ccaaaaaaat cggttttcaa agtctgacgg acttcaaaat cacgatttca acagaactac
     7321 agactggaat cgatgaaggt tttagtgata tagaagcaaa tgagtccttt tactctatca
     7381 aaaacaaact tggtaacaat gcacaagtag cgataaaaga aacagtagat attctagaag
     7441 aagaaacgat ccaaaaagtc gtagagtgtt tggaatcggc agagactgtt tttttatatg
     7501 gggttggcgc ctcttcttta gtagtagaag atattctgca aaaatggtct cgtgtcggta
     7561 agccaatcat ttttgaaaaa gatatccacg tcttgctccc gcaacttgtc agcaatgaga
     7621 aaaagaaagt gctttggctt gtttcaaact caggtagaag tgcagatgta gtcgcattag
     7681 ccgagctggc gaaaagcatg aatatcgaaa tcattgcgtt gacgcaattt ggaaataacc
     7741 cgcttagcaa gatagccgat gtactcgtac aaacatctag accaaaagaa atcacgaatc
     7801 gaagtgcggc aactaattca cttttggccc aatttgctac gatcgatatc attttttatt
     7861 tctatatggc taaaaacgaa aagcttagcg aaaaagtgaa aaaaacacga gaagcaatcc
     7921 aagaatattt tatggattcg aaataaaaac cttactattt tttatataag ttttttagaa
     7981 taacaaaacg tagttttcca caaataaatg atccatcaaa gtgtttcacg acttaagaaa
     8041 acataatttt caaaaataag tttatttttt aatgaaaaaa atagttggat atgtaacttt
     8101 aagtgattgc tgtgaaacaa aaagttgatt ttatcttgaa attaggtaaa gaatttcttg
     8161 ctccgcccat tttttctttt ttattaagaa gtttttgggt acaatgaagc atgaatgtaa
     8221 ataggcggaa ggataggaaa tgatgaaaga ttttatgaaa aaaatattaa atacttcttg
     8281 tttattaaga agtttttggg tacaatgaag catgaatgta aataggcgga aggataggaa
     8341 atgatgaaag attttatgaa aaaaatatta aatacttctt ggttagaaaa aataagaaaa
     8401 ggtgcacaag aacctaagaa caaaacgttt cgccggtccc atgttccttt tcgcttaaat
     8461 tttctttttt tcattatatt tacgttattt gttgcgttga ttgctagatt gggttatttg
     8521 cagatcgtga acggcgaaga gatggaggcg cgagtgaagt ctacttctac gattacggtc
     8581 caagaaagta ctcctcgcgg aatgatctac gactccacag gaaaagcttt agttacgaat
     8641 aaagcgaatc aggccatcac atatacgaga ggaacacaag ttacggctaa agatttgctt
     8701 gaaatcgcaa cgaagctgaa ctcgctgatc gatgttccgg tagatgaaaa tctgacagat
     8761 agagataaaa aagatttttg gctggctgat cccaaacatt tgaaagaagc cacaaaaaga
     8821 ctttcggcaa aagaaaagca attagggaac agcgaacaat atagtgcgat ggtcaataaa
     8881 gtcacagctg atgagattaa tttaaacgag gagcaattaa aaattgctac catctttaaa
     8941 cggatgaata gtgcatatga attaaacact gtctatatca aaaactctgg tgttactgat
     9001 caagagttag ctgttgtggc agaacgcgct tctgaacttc caggagtttc gactggcaca
     9061 gactggacac gagaatataa tgcagcaagt tcactgaaaa gtattcttgg cagtgtgacg
     9121 actgaaaagc aaggacttcc agcagatgaa gcagagaaat acctagcaaa aggttattct
     9181 cggaatgacc gtgtaggaca aagttatttg gaaaaacaat atgaagatgt cctgcaagga
     9241 accaaaaccc aatatgaagt ttcccttgat aatgaaggaa atgtttcgaa tcaaaaagaa
     9301 atcttctctg gggaaaaagg ttctaattta atgttatcta tgaatgcaga attccaatca
     9361 aaagtagaag aaattttgaa aaggaattat caaacattga tcaacaacgg caaagcacag
     9421 tattcgcctg gtgcttatgc agtggctatg aatcctcaga caggagaagt gctagcaatg
     9481 actggtttca gtcatgaaca aggttccaaa gaaatcaccg agaatgcttt aggcacgatt
     9541 actagcgcct ttgatccagg gtctgtagtc aaggctggta ctttgacagc aggctgggca
     9601 agtaacgcga tcagcggaaa tcaagttttg attgatgagc cgattcgtct gcaaggtgct
     9661 tcagaaaaaa gctctgtctt taatcgaagc ggacaagttg ctcttgatgc agtcaaagca
     9721 tcggaattgt cttctaatac gtatatgatc aaagtggcgt taaagatgtt aggactagac
     9781 tatacacctg gaatgggact acctagttta gatgaagaag ctaaagctta tcagcaattg
     9841 agagactctt tcaaagagtt tggtcttggt acaacgactg ggatcgattt gccgaatgaa
     9901 tctcctggga tctcacgttc tgttgattat atgaagaagt tcaatgcgga taatggcaaa
     9961 gaatggtatg ctccaggtaa ctttaccgat ttggcatttg gacagtttga cacatataca
    10021 ccaatccaat tagctcaata tgcttcaaca gtcgctaatg gcgggaaacg agtacagccg
    10081 cacctagtca aagcgatcta tggcaatgac gaaaatggaa acttgggtga agtgaagaaa
    10141 gaaattggca caacagtaga aaatacggtc aatatttctg cagaaaatat ggcgatcctc
    10201 cgtgaaggat tccaccaagt tgtccatggt accgatcctt acacaacagc caaaccatta
    10261 gccagtgcga aaatggacct ttccgcaaaa acagggactg cagaaacggt tgcggaaggt
    10321 catccagata ttgcgacagt caatagtaat atcgtggcat acggaccaac agacaatccg
    10381 gaaattgcca tcagtgttgt cttgccgaac ttattagacg aacaagacca cataaacttg
    10441 acgattgcta aagaaataat ggacgcgtat tatgatatgt tcatggcaaa ataaaaaaga
    10501 ggtcgtgaaa aagccgctta gtttcgagta tgaagaaaaa ttttgtgaaa atagcttctc
    10561 acatttttgc ttaaatttga cttcataccg agaaactggc ttttgaacac cgtttactcg
    10621 gcaaaaaagg ttgtgacaaa aattgtcaca acctcttttt tgtggaatct aattctctat
    10681 tatagtttaa gtagtttttc cagataaaca gctaaaccgt cttcctgatt gctcaaagga
    10741 gtgacatcat ttgcaatgcc tttgagttgg tcagtaccgt tagccatagc tactccccaa
    10801 cctgcataat ccaacaattc caaatcatta tgctcgtcac caaaggcaat gacgtctttt
    10861 tgatcgatag acaggtagtt agcaatctct tgcacgcctt ttgctttttg gattcctttt
    10921 gaaacaatct ctaagatggc agtaggtcca ccccatgtcc gaacatcgac ataactgcca
    10981 aattgacgtg ttaattcagc agatacagct cctgcaaaac gtttgtctgt tcggacaagc
    11041 aaagatgtag gatttgtcgt caaattttta ggagaaagca aattcttctc tcctggacga
    11101 gaagaagcaa aaattttttc atcaaagaaa tcaaaactgt caataaaaaa agtatcacga
    11161 ttttcagcag cgataaaatc taaatttagc tgcttttttt gcgataagat ttcaaaagcg
    11221 atttcacgat tgatcaacgt ttctctttca ccatcccagt gctgattagg gatgtgtact
    11281 aatgcgccgt taaaattaac catcggtgtt gttaattcta attgttggta aaactgatgg
    11341 ctcattcgga atgggcgtcc tgtagcaata ctgacatgat gaccggcatt gattgctttt
    11401 tttagagtct cttttgtttt agatgtaatc atcgaatctt gattgagggt agttccgtcc
    11461 agatcgatgg caattaattt tttattcaat aagggtcctt ccttcctcaa ctagcatttg
    11521 ttttagtcta gcatatttta ggtaattaac aagagcaatc agctattcct aacaaaaact
    11581 acagttatgg ctatataaat agctaaacat aagctaaaca cgaacgttaa gtattatttt
    11641 cgcttttttt gttaaaaaaa cgttgaaaag cgaatgaaac gtctatataa tttgaaattg
    11701 ttcgatggat ttgccctatt ttacttattt tttattatta tagttttcca tcagaaaaaa
    11761 attcagggag tggaactttt tatggaaaag tttttcggtt taaagaaaaa caatacaaat
    11821 gtatcaactg aaataatggc gggagtaacg acattctttg ccatgagtta tatcttattc
    11881 gtaaatccga cgattttgtc agcatcaggt atgcccttcc aagcagtatt tctagcgaca
    11941 atcattgcat cgattattgg tacgctggta atgggattgt tcgcaaatgt accatatgct
    12001 caggcacctg gtatgggatt gaacgcattt ttcactttta cggtcgtttt tgggcttggt
    12061 tattcttggc aacaagcctt ggcaatggtg tttatttgcg gattaatcaa tatttttatt
    12121 actgtcacaa atattcgaaa aatgattatt cgggcgattc ccgaaagtct tcaacatgcg
    12181 attggtggcg ggatcggtat tttcgttgcg tatgtcggaa tcaaaaatgc aggattctta
    12241 tctttttcag cagaccagtc agctatttcg agctctgtcg ttgaaggcgg aaaagcgaca
    12301 aatgttacga taaatggtgg aatcgtccct gcgttagcca actttgacaa cgctcctatc
    12361 ttattggctg tgattggttt ggtactgaca gccattttag ttgtaaaaaa tgtccgtggg
    12421 gctattctta tcggtatcgt agcgaccaca gtccttggta tttttatggg tgttgttgat
    12481 ttaagttcca ttgattggca aacgaattcg ttaggtaatt catttaaaga attaggaaca
    12541 actttcggtg cagcatttgg ttctgaaggc atgcaatctt tattcagtga ttcttccaag
    12601 attcctcaag tattgatgac gatcatcgca ttcagtttat ctgatacttt cgatacgatc
    12661 ggaacattta tcggtacagg acgccgcaca ggtattttct caaaagaaga cgagatcgcg
    12721 ttggaagatg gtcgtgggtt caaaacaaaa atggataaag cactatttgc cgatgcgatc
    12781 gctacttctg tgggggctat ctttggtaca tcgaatacaa caacttatgt cgaatctgca
    12841 gctgggatcg gggccggtgg acgtactggt ttgacttcag tagtagtggc agtgctattc
    12901 gcattaagta gtttattctc tccactgatc gccattgtac caaatcaagc aactgcgcca
    12961 gcattgattt tagttggagt aatgatgatg gcttcttttg cagacatcaa atggctagat
    13021 atggaagaag ctttaccggc cttctttgca tcgatcttta tgggattgtg ctatagcatt
    13081 tcctatggga ttgcagcagg atttattttc tatacaattg tgaaagtaat caaaggaaaa
    13141 tacaatcaag tttctgttgc tttgtggatc gttgatattt tattcattat caacttcatc
    13201 attctagcaa caatttaact aaagagaagg gattggaaca gtatttgttc tgatctcttt
    13261 ttgttttaca taaaaagaac gttacatata aaatgacctt tgcgggattt ttctcttttt
    13321 actggcgaga tcgttgcttg tttattcgaa aataggtatg ataaaagaga cgaaagaggg
    13381 atgatagatg gagattaatt ggagaaaaaa tttagtgatt gcgtggattg gctgtttttt
    13441 cactggtgca agtattagtt tagttatgcc attcatacca gtttatgttg agcaactagg
    13501 aacaccaaaa gatcaaatcg aattgttttc gggactagca atctctgtga ctgcttttgc
    13561 atctgccgtg gttgcaccaa tctggggaaa tctagctgat cgaaaaggcc gaaaactcat
    13621 gatgatccgt gcagcagcag ggatgacatt aacaatggga tctttggctt ttgtaccaaa
    13681 cgcgtattgg cttttgatca tgcggttttg gaatgggatt ttgtctggat atattccaaa
    13741 tgccacagcg atgattgctt cacaggcacc tagagaaaag agcggatggg cgttaggaac
    13801 attgtctacc ggagcgattg ctggaaatct gatcggacct tcaatgggcg gtgcactggc
    13861 tcagtggttt ggtatggaaa atgtattctt gatcacaggg gctttgttga tgatcacaac
    13921 ggtattgacc attttcttag tcaaagaaga tttccatcca atcgagaaaa aagatctgat
    13981 aagcaccaaa gaaatttttt caaaaatgga tcatctctct attttgatcg gtctcttcat
    14041 tacgaccttg attttacaga taggaatcac tacgatcagc cctattttga ccttatatat
    14101 tcgtgaattg agcggaagta cagaaaatat cctttttgtc agcggcttga ttgtttcgat
    14161 agctggtgtt tccgctgtct tttcttcacc gaaactagga aaactagggg ataagattgg
    14221 gaatcaaaaa gttctaattg gaggactcat tttatcattt tgctgttatt tacctatggc
    14281 attcgtcact acaccgctcc aattaggtat acttcgcttt attttaggct tttcaactgg
    14341 cgctttgatg ccttctgtca atacactgat cagtaagatt acgcctcaag aaggagtcag
    14401 ccgaatctat agctacaatc agatgtttag caactttgga caagttttag gtcccatgct
    14461 aggatcgaca gtcgcgcatg cttataatta cagtgctgtt tttattgtga caagtttgtt
    14521 tgttctgtca aatattcttc tttctttatt caactttcgt aaagttcttc gcagcagatt
    14581 ataatggtgg tgaggagtag aaaataaaaa agagcttgag aaatctcaag ctcttggctg
    14641 tttttttacg aatgggcaga ggtttctttt cttggcgcaa ctgcaccaat caaaaggata
    14701 atgacacccg caatgaatga aatgattgtt gtcaaagtaa aatcatatgt tccgcttgtt
    14761 aatgcagcac caatataacc gactacttga cctagaacga cagcccagaa taatgtaacg
    14821 atatatcgca taaagaacac ctcttttcta tcttaatttt accagatttt ctttgaatgt
    14881 aaagaaacga gaccaaatct caataaaatt tgagttcttg cgaaagaact cattcctaca
    14941 gattacaagc aagcaaatga agtggaataa tcaacttcag cgcctgctat cttaatgaaa
    15001 gtaaaaggat caaacctttt aacgctagtg aattttaacg aaaaaaaagg cggaatgcaa
    15061 gatgtttttc ccacaacttt atacaattac ttcttattct cttttacaaa gtacgatacg
    15121 tattcgagaa tatgtacaag aagcaaaaaa acaaggctac acttcattag ccataacgga
    15181 taaagatgtc ttatacggtg cacctgaatt ctatcgtatt tgtgtagaag aaggagtaca
    15241 gccaatcatt ggattacatc ttagttatac ttatgaagaa aaaaattatg gcttgcttgc
    15301 gtacgcaaaa gatgaaatag gttatcagca gctgatgaaa ctttccagcc gaaaaatgat
    15361 ccaagaaaaa ttggaacttg cagaaatgac agaaaccgac catctagcgt ttgttgttcc
    15421 ggcaaatcat tctgtttctg aggctttcaa taaagaggat aactttttcg gtcattggca
    15481 gtttttactt gaaaatgttt ttactagaaa tttttatatc ggcttgacag aaaacacgcc
    15541 tgatcaattg cctgaatggt atcagtatgt gataaaagaa aattattcgc tttgtgcatt
    15601 acatcccatc gctagtttac aacaagaaga actttttgca cttgaagtga tgaaacatat
    15661 caaagaggga agccaaatac ctttagaaaa tttatctgca tctttaccac taacagcaaa
    15721 tgtctatctt ctttcagaac aagaaatgat caaacgattc gaaaaagcgg gtctttccca
    15781 agctgtaata ggcgcccagc gtttagctga atcgatttca tttgaattcc agttccatca
    15841 gaaattactt ccgcattatc cagttcctaa tggaaaacaa gctggagaat atttaagaga
    15901 gttatgctat tcgcaagtgg aacgccgaat cactgactat acaaaggaat accaagaacg
    15961 tttggactac gagttatctg tcatccatca aatgggattc gatgattatt tcttgatcgt
    16021 atgggatgta atggcttttg ctcatagaaa caaaatcgtt accggtgcag gtcgtggttc
    16081 tgctgcgggt tcattagtag cctatgtgtt agaaatcaca gatgtggatc cattagaata
    16141 tgatttgctg ttcgaacgct ttttaaaccc cgaacgcttt acgatgccag atatcgattt
    16201 ggatattcct gacaatcgac gtgaagaagt attgaattat gttcgagaaa agtatggaca
    16261 atatcatatg gcacaaatcg caacatttgg cacaatggca gcaaaaatgg ttcttagaga
    16321 tgcagctaga gtgtttggtt tatcgcaaag tgaagcaaac cgctggtcaa aagcaatacc
    16381 caatcaattg aaaatcacat tgacccaagc ttataaaact tcgcatcaat tagtagaatt
    16441 agttcaggca agcgaaaaaa accaactttt attcaaaact gcagtgattt tagaaggatt
    16501 gccaagacat gtttcgactc acgcagcagg tgtagttatc agcgataaga atctacttga
    16561 actagttccg ctccaacgcg gttctgatga agcttttctg acccagtata cgatgaatga
    16621 ggtagaagca atcggtcttt tgaaaatgga ctttttagga ctacgcaact tatcgattat
    16681 tgattttact ttgaaagctg ttaagcgagt agaagggtat gagatccgat taaaagagat
    16741 cccgctaaat gatgcaaaaa cgctgctctt gtttcaacga ggcgaaacct caggagtatt
    16801 tcaatttgaa tctgctggta tccggaacgt tttacgaaga ttagatccag aaaacatcga
    16861 agatattgcc gcagtcaatg cattgtatcg accaggccct atgcaaaata tagatacctt
    16921 cattgccagg aagaaaggaa aagaagccat tcgctaccca gatgattcac tgatcccgat
    16981 tttgaaaaac acatatggag tgatcgtcta tcaggaacaa atcatgcaga tcgcctcgac
    17041 tatggctgga tttacattag ggcagtcaga tattctgcga cgggcagtga gtaaaaagaa
    17101 aaaagacgta ttagatgaag aaaagtcgca ttttgtatca ggagcattac aacagggata
    17161 ttcggaaaaa acagcagcga ccgtatatga atatatcgaa aaatttgcaa actatggatt
    17221 caatcggtca catgcatttg cttattcatt cgtgggattc caaatggcgt atctaaaagc
    17281 ccatcatcca ggtgctttct ttaccagcct gatgaattct gttcggcata acacatcaaa
    17341 attgaaagaa tatattgcag aagcacgtaa aaataaactc aaactttcct cgccgtccat
    17401 taatcaaagt aattccagtt ttgagttggt caataaggaa gaaatcagat tcggactgac
    17461 agcgataaaa ggtattcggc gtgattttgt agaagatata ttaaacgaaa gaaaacaaaa
    17521 tggcccgttc cagtcagtgg atcaattcct catacggatc gataagcgtt ggctgaaatt
    17581 agagttactg caatcactga cagcagtagg agtttttgat gaattatctc ctaacaggaa
    17641 acaattgatg cttgatctcg aaggaaaaat ccaaaatatc gtttacagtg gtggaagtct
    17701 tgacttgctg ggaatcatgg cattaaaaga agaagaagtc gctgactata cactagaaga
    17761 acgcttgaag ctggaagagg agtacttagg tatttatttg tcaggtcatc ctgcagaagg
    17821 gtttgatcgt cttcgtttag ctaaacaagt tcagctgatt acagatatcg tccctaatca
    17881 accagtcaat ttattagtga tgatcaagga agttagagaa attcggacaa aaaaaggaga
    17941 actgatggcc tttgttgaag gaaccgacag tagtggagaa atttctgtca cagtttttcc
    18001 aactctttat cgtaaatatc gtaatttgtt tgccgttgat cgagtgatct ttgttcaagg
    18061 gcggagcgaa atcagcaaat ataatcagga actgcaacta attggagaaa gctttgctga
    18121 tcctaaccag ttagaagccc agtatccttc acaaacttgc tatttgcgta ttacagaaga
    18181 acgggaagat cccgagataa tgaaacaatt acaagtgatt tttcagaaac acccaggata
    18241 tataccagta gttatgtatc acgaaaaaac gcaacgaaaa gtagttctgt cagatgctta
    18301 ttgggtggat gacagcaaga gtataaaggg gcaacttatt tatctgcttg gcgaagataa
    18361 tgtggttttc aaataactta cggtaaaaaa tactacttgc tttcattttt ttcatttttt
    18421 tatccgtaaa tcaagacaag tgagaaaaat aatgttagaa tgttagtcgt ggttaacgca
    18481 aaaatggttg taaacctaag tcatacttag gataaagtat tttaatgagg tgaatgttta
    18541 ttatgaaacg catcggaatt ttgaccagtg gcggagacgc acctggaatg aatgcagctg
    18601 ttcgtgccgt tgttcgtaaa ggtatttacg aaggactgga agtatacggg atcaattatg
    18661 gttttgccgg tttagttgct ggagatattc gtcgtcttga tgtggcagat gtaggtgaca
    18721 agatccaacg tggtggtaca ttcttgtatt ctgcacgtta tccagaattt gcaactgaag
    18781 aaggtcaatt aaaaggaatc gaacaattga aaaaattcgg aatcgaaggt ctagtggtta
    18841 tcggaggaga cggctcttat catggcgcaa tggctttgac aaaacgcggt ttcccagcag
    18901 taggtattcc tggaacaatc gataatgata ttcctgggac tgatttcaca atcggttttg
    18961 atacagcaat caatacagta ctagaatcaa ttgaccgtat tcgtgacaca gcgacttctc
    19021 atgttcgtac attcgttatc gaagtaatgg gacgcaatgc aggagacatc gctttatggt
    19081 caggtgtggc tggcggagcg gatgaaatca tcatcccaga acatgatttt gatatggctt
    19141 cagttgctaa aaaaatccaa gaaggccgcg atcgcgggaa gaaacattgc ttgatcatct
    19201 tggctgaagg tgtaatgggc ggaaatgaat tcgctgagaa actttcagaa tttggtgact
    19261 atcatacacg tgtatctatc ttgggacacg ttgtccgtgg tggagcacca agcgcacgcg
    19321 accgcgtgtt ggcaagtaaa ttcggtgctt acgctgtcga attgcttcaa gaaggaaaag
    19381 gtggattatg tgtcggtatc catgacaacg aaatcgttgc gtctgacatc attgatacac
    19441 ttgaaaacaa caaacataaa ccagacttat cactatatga tctaaataat tcactttcat
    19501 tttaagagtg aaagaaacca agctatttaa gctgtgtaca gctttaaata aacaaaattg
    19561 aatgggagag ttttttaaat gaaaaaaacc aaaatcgtta gtacattagg accagcaagt
    19621 aactcagtag aaattatttc tcaattgatt gaatctgggg caaatgtctt ccgctttaat
    19681 ttttctcatg gtgaccatga agaacaatta tcacgtatga ctatggtccg tgaagcagtt
    19741 aaaaagacag gaaaagatgt cggtattctt ttagatacaa aaggagctga aatccgtaca
    19801 actgttcaag gcacaacaga agctgatttt ggtcgtgcag gatacatcaa atttgaagta
    19861 ggagatcaaa cacgcatctc tatggatcct gaacatgtag gttcaaaaga aaaaatcgcg
    19921 gttacttacc caggattatt tgacgatgtt cacgttggcg gacacatttt atttgatgat
    19981 ggtttgatcg atatgcaaat cattgaaaaa gacgaagcaa accgtgaatt agtcgtagaa
    20041 gttaaaaatg caggtatgct aggatcacgt aaaggggtaa atgcaccagg cgtttctatt
    20101 agtttgccag gtattactcc aaaagatgct gacgatattc gttttggttt agacaacgat
    20161 atcgacttta tcgctgcaag ttttgtacgt aaagcacaag acgttctaga tatccgcgaa
    20221 atcttagaag aaaaagacat gactcatgtt caaatcttcc ctaaaatcga atctcaagaa
    20281 ggtatcgaca acattgacga aatcatcaaa gtttctgacg gtgttatgat tgcccgcgga
    20341 gatatgggtg ttgaaatccc agctgaacta gtaccaatgg ttcaaaaacg cattatcaaa
    20401 aaatgtaatg ctgctggtat cccagttatc actgctacac aaatgttaga atcaatgcaa
    20461 gaaaacccac gtccaacacg tgcggaagct tctgacgttg ctaacgctgt atttgatggc
    20521 acagatgcaa caatgctatc tggtgaatct gcaaacgggg actacccagt tgaagctgtt
    20581 tcaacaatgg cacgtatcga ccaagaagct gaaaatgcat tatcagaatt aggtacattc
    20641 caattgaacg aattcgataa aacagatgta actgaaacaa tcggtttatc tgtagctcgt
    20701 gctgcaaaaa atctaggcgt gaaaacaatc gttgctgcaa ctgaatcagg atacactgca
    20761 aaaatgattt caaaatatcg tccagatgca gatatcttgg ctgttacttt tgacgaacgc
    20821 acaaaacgtg gtttgatgtt aaactggggc gtttacccaa cagttgctga aaaaccatca
    20881 acaactgatg aaatgtttga actagcagct aaaaaagctg ttgaattagg tttcgcatca
    20941 gaaggcgatt taatcttgat cactgctggt gtaccagttg gtgaacgcgg aacaactaac
    21001 gtgatgaaaa ttcaaatgat tggttctaaa ttattagaag ctcaaggcgt tggacaaaaa
    21061 tctgtcgttg caaatgcagt tattgcttca tctgctgaag aagctgtaaa aaaagcaaaa
    21121 gacggaatgg ttctagttgt accatcaact gacaaagaat atatgcctgc aatcgaaaaa
    21181 gcagctgctg ttatcgttga agaaggcgga ttgacttctc acgctgcagt tgtaggaatt
    21241 gcacaagata ttcctgtaat cgttggtgct aaaggcgcaa caacaacaat tacagaaggt
    21301 gaattgatta ccgttgattc acgtcgcggc atcgtttacc gtggcgaaac aacagctatc
    21361 taatttagct taataaaaaa taaaaacagc tcttctttta cgaagagctg tttttttgtg
    21421 ctgtaacgaa ttcatggata acttggacta cttgttcttg aagaggcgtg acgatctgct
    21481 gtgttcgttt tgccaatgaa atcaagaagc gaggctgaac ttcatctgaa agagggaggc
    21541 aaactaaatg atcttcagga tggacagcaa tctctgccaa aaaaccgata cccacatttt
    21601 ctcggaccat actctttaaa atcgtcaagt cattgctttg ataaacaact tttggatgag
    21661 tatgtgtttg tttagaaagc ttagtgaatg ctgcggggtg gacataatgt tcgttcaata
    21721 gtacaaactg ttcatctgct atatctttga aagagacagt atcctgcttg gaaagaggat
    21781 gtgtaggtgg cacgacgatc atgaaacgtt tgtccaaaag taactctgtt tctaaatatt
    21841 gatccacgat tggctgtgtt gagcctaata cagctaaatc gatcctccct tgtcggatca
    21901 tcccgtataa gtcccgagag cctccatcgg taatctcaat ttgattcatc aattcatgct
    21961 tgataaagta acttgacagt ttaggaaagt attcattgcc gataatagga ggcatgccaa
    22021 aacgaagctt tttcttttgc aactgagtga tttcagctct tgcagtagaa atctcttgga
    22081 gaatggtttg tgcatggaga aacagctgct ttccagaagg cgtgacgatt aattcgtgat
    22141 gcgatcgatc tcttgtaata agtacggtgt caaactcttt ttcaagacgt tgtaatgcat
    22201 atgtaatagt aggttggctc acacggaaat aattagccac tttcgtaaaa tttttttgtt
    22261 tgacgatttg gacatagtat tcgatatctt tcgtgttcat gaagatcatc cgctccttta
    22321 atggaataat gattattgta aatgattctg aggatgatag caaacagagg ctttctaata
    22381 aagatttttc tgttttttta tgaactgcaa ggtgtcaaga aaatttcatt gacaacatgc
    22441 tttttgccct gtataattgc ttttgttgct taggagtgat gaaaaatgaa atggtcttta
    22501 ttggaattga gaaaatacca ggagacaccg ttaacttttc atgagacgct cgacttgaaa
    22561 gccgctctca tgaagcgaga caatttaata cttgatgttg cgccagtgga agtcgaaggt
    22621 ttggtctcag ttgataagaa aggctatatc gttcattaca ctgtgcagac gactttgaca
    22681 gttccttcaa cacgttcact agaacctgtt gaactgccca tggatttttc tgtagacgaa
    22741 gtattcatga cagaagaaca attccaaagt agagatgaac aaatgtctgc agatgagatt
    22801 ttgctaattg aaggtccatt attgaattta gcagagtcga ttgaagacaa catcttattg
    22861 gcgattccaa tgcgggtatt gacaaaagaa gaggaagcag caacagaact tccaaaaggc
    22921 aatgattggg aagttgtttc cgaagaagaa taccagcgca gaaaaatgga agaagccgag
    22981 aataaaattg atcctcgtct tgcaaaacta tctgaacttt ttgattctaa atcaaaagac
    23041 gacgataaca agtaagattg gaatatattg tgtctaattt agatacaaga ctttacaagg
    23101 aggtgtagca aaatggcagt accagctaga agaacatcaa aagctaaaaa agcaaaacgt
    23161 cgtacacact acaaattgac aatcaaaggg ttaaacgaat gtccaaactg tggtgaaatg
    23221 aaaaaaagcc atcacgtatg tgcaaattgt ggttactatg atggtaagga cgtaatgtca
    23281 aaagaagctt aatacatttt aattagaaaa tgtaaaacct caaggctaac catggagcct
    23341 tgaggtttat ttttttgtag tcggtaaata aaaaat
//
LOCUS       DACDLM010000047        22582 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.047, whole genome shotgun sequence.
ACCESSION   DACDLM010000047 DACDLM010000000
VERSION     DACDLM010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22582
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.047"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            626..1489
                     /locus_tag="IV356_001825"
     CDS             626..1489
                     /locus_tag="IV356_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP9015513.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1618..3240)
                     /locus_tag="IV356_001826"
     CDS             complement(1618..3240)
                     /locus_tag="IV356_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP9015514.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3489..4010
                     /locus_tag="IV356_001827"
     CDS             3489..4010
                     /locus_tag="IV356_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015515.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4196..5926)
                     /gene="spxB"
                     /locus_tag="IV356_001828"
     CDS             complement(4196..5926)
                     /gene="spxB"
                     /locus_tag="IV356_001828"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HAP9015516.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            6091..6909
                     /locus_tag="IV356_001829"
     CDS             6091..6909
                     /locus_tag="IV356_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005232914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HAP9015517.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(7012..7209)
                     /locus_tag="IV356_001830"
     CDS             complement(7012..7209)
                     /locus_tag="IV356_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015518.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7378..7956
                     /locus_tag="IV356_001831"
     CDS             7378..7956
                     /locus_tag="IV356_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAP9015519.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            complement(9001..9504)
                     /locus_tag="IV356_001832"
     CDS             complement(9001..9504)
                     /locus_tag="IV356_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAP9015520.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9863..10888
                     /locus_tag="IV356_001833"
     CDS             9863..10888
                     /locus_tag="IV356_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP9015521.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            11211..12089
                     /locus_tag="IV356_001834"
     CDS             11211..12089
                     /locus_tag="IV356_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015522.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            12565..12681
                     /locus_tag="IV356_001835"
     CDS             12565..12681
                     /locus_tag="IV356_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAP9015523.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13609..13947
                     /locus_tag="IV356_001836"
     CDS             13609..13947
                     /locus_tag="IV356_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015524.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            14041..14271
                     /locus_tag="IV356_001837"
     CDS             14041..14271
                     /locus_tag="IV356_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015525.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            14671..15042
                     /locus_tag="IV356_001838"
     CDS             14671..15042
                     /locus_tag="IV356_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HAP9015526.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(15316..16008)
                     /locus_tag="IV356_001839"
     CDS             complement(15316..16008)
                     /locus_tag="IV356_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP9015527.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(16011..16796)
                     /locus_tag="IV356_001840"
     CDS             complement(16011..16796)
                     /locus_tag="IV356_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP9015528.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            17033..18433
                     /gene="lacG"
                     /locus_tag="IV356_001841"
     CDS             17033..18433
                     /gene="lacG"
                     /locus_tag="IV356_001841"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HAP9015529.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            18458..18775
                     /locus_tag="IV356_001842"
     CDS             18458..18775
                     /locus_tag="IV356_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAP9015530.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            18788..20461
                     /locus_tag="IV356_001843"
     CDS             18788..20461
                     /locus_tag="IV356_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP9015531.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            20475..22106
                     /locus_tag="IV356_001844"
     CDS             20475..22106
                     /locus_tag="IV356_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-1,4-beta-galactosidase"
                     /protein_id="HAP9015532.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
BASE COUNT         7027 a         3817 c         4553 g         7185 t
ORIGIN      
        1 aaaaaccgtg tcacagtccc tttttccgaa caaacggtgt tcaaaagctt gcatctacgg
       61 cactaagccc aatcagatga aaaatatgga gtgctatttt tatctgattg ttcttactgc
      121 ttgatgcaga gcagcttttt cacaacctct ccactaaacg gtgttctcct gccaactcct
      181 cggtcacaag tcacaatatt caacaaacat gagaagctgt tttttgaaat tgttccttgt
      241 gactcggagc taaacggcag gctcacaacc tcttggtaaa cggtgttcaa tcagctgacc
      301 ctcggtatta gctcaaaaaa cggcaaaata tgaggaacta ttttttccgt ttttttctct
      361 aatactcagg tcaaaacgct gatttcacaa cctctgattc acggtgttcc agaagtagct
      421 tctacggaaa taagccgaaa tttcacaaaa atttgagaag caattttcgt aaattccttc
      481 ttatttcttg aagctgacca cttctgtcac aacctcttat tttgattaga acttgcgaaa
      541 ataaaccggt taaagtgtgt ctagcgcaag agatttgcta taatagacga taagggtaaa
      601 atgtaacgag aaggggttga aaaatgtgta tcaaattgta acagattctt gttgtgatct
      661 gccataccat gtattagcaa aagaaaaagt tgatttttta tcaatgaatc tccaattgaa
      721 tgatcaagag ttagtagatg acctcggaaa gacattcaat tatgaccgct acatgaatca
      781 gctgaaaaat ggtgcgatgc ctacgacatc acaaatcaat gttggccgat atttagaatt
      841 tttccgttct tatgcggaaa aacagattcc tgttttatat gtggcttttt ccagtggatt
      901 aagcggctct tacagtagtg cgcttcaagc ggttgaattg ctgaaggaag aatatgaaga
      961 ccctgagatc tatgtttttg atacaaaagc tgcaagtatt ggggaagggc ttttagtatt
     1021 ggaagctgta agattgaaaa aagaaggtaa aagcatcgaa gaaaccctag agtggctgga
     1081 aagtaattat ttgaaagtcc attcatgggt aacagtagac gatctgaaat atctagaacg
     1141 aggcggtagg atttccaaag caagtgctac tcttggcagt ctattgagtg taaagcctat
     1201 tattacggtg gataaagaag gaaggctgac gaatgttgac aaagttcgag gaagaaacaa
     1261 gtcgatccag acaatcgtca atgagacggt aaaaacaatc gttgcaccac ttgatcaaat
     1321 cgtttatgtg gcttacgctg gggatctaga gagcgcggag aaggcaaaac ggcttttgga
     1381 agagcagata aagatgaaag atgtgaagct ttatccctta ggaccaacga tcgccagtca
     1441 cacaggctat ggctgtatcg cgattttttc gatgggaatc agtcgataaa agcagtaact
     1501 cattctgtaa aaaagcccag aaattgattg taacaaaaac agcgactctt aaaagataga
     1561 tgagcatcct atctcttaga ggtcgctgtt tttttatttt ttaagctaaa taggccatta
     1621 tgcccataac tcgttcaatt gtttttgaat atctgcattt tccaaaaatt catcatatgt
     1681 cgtatcagct cgatcgatca cacctttatc cgaaacggca atgatgcggt ttgccaatgt
     1741 ttggataaat tgatggtcat gtgacgcaaa taagattgag ccagtaaatg ccatcaagcc
     1801 gtcattcaat gctgtgattg attctaagtc taaatggttc gttggatcat ctaatacaag
     1861 tacgttagct ttcgaaagca tcatttttga aagcatgcaa cggactttct ctccaccaga
     1921 taaaacattc actggtttca atacttcttc accagaaaac aacattcttc ctaagaagct
     1981 tcttaagaag gtgttatcat cttcttcttt acttgcatat tgacgcaacc agtctaaaat
     2041 cgttagatca gtatcgaatt ctttcgttgt atcctttggt aaataagaat tacttgttgt
     2101 cacaccccaa cgtactgttc cagtatctgg cgtaatttca cccatgataa ctttgaatag
     2161 cgttgttgtt gttatatcat tttctgcgac gaaagcgacc ttgtcttctt tgctcaaatt
     2221 aaaagatata tcatctaaaa ttttctttcc atcaatcgtt acacttacat tttctacctg
     2281 caataagtcg tttccaatct cacgttcagg tttgaatcca acgaatggat aacgtctaga
     2341 agaaggttgg atatcgtcta aagtaatttt ttcaagcatt tttttacgtg aagttgcttg
     2401 ttttgatttt gatgcattcg cactaaagcg ggcaataaat tcttggagtt ctttgatttg
     2461 ttcttctttt ttggcatttg cgtttgcttg aagtttagcc gctagttgac tagattccaa
     2521 ccaaaaatca taatttccta cataaagttt gattttacca aaatctagat ccgccatatg
     2581 tgtacatact ttgttcaaaa agtgacggtc atgggataca acgatcacag tattttcaaa
     2641 attgatcaaa aattcttcca gccaattgat cgattggata tccagaccgt ttgttggttc
     2701 gtctagcaaa agaacatcag gtttaccaaa tagtgtttgt gctaataaca cttttacctt
     2761 ttgtccacca gttaattcac tcatttgctg atggtgcaat tcttcaggga tgttcagacc
     2821 ttgcagtaaa acagctgctt ctggttcagc ttcccatcca ttaagctcag caaattctcc
     2881 ttctaattca gctgctcgaa taccatcttc gtcagtgaaa tcctctttca tgtaaatcgc
     2941 atctttttct ttcagcactt catacagacg cttgtgtccc atgatgactg tttcaagtac
     3001 agtatagtct tcatagtcgt aatggttctg tttcaatacg gccatccgtt catctggtcc
     3061 catagtaacg gaacctgtgg aaggctgcag atcccctgat aacactttaa ggaacgttga
     3121 tttacctgca ccatttgcac caatcaagcc atagcagttt ccgggggtaa atttaatatt
     3181 cacatcatca aatagtttgc ggtctgaaaa gtgcaaactc acatcattta cagtaatcaa
     3241 tttttttcct cacttttatc attattagtt ttgacaagtc ttatagaatt atatagggga
     3301 aaggtaaaag attcaaggca atcgaacatt ctttgtgttt cacgtgaaac agaatgaaaa
     3361 aaataaaaat aaaagcggag cgaaaatagc tactatagga tttattagtt tgcaacagca
     3421 taatttttga cgttatttat aagagggagt actataaaac tgtaaaagaa atgaaagaag
     3481 gattgaaaat ggatgaaaaa agaaccatcg actggggctc attgattttg ggaattttat
     3541 ttgtacttgt ctcattgtta tcatttcaag accctgtcgg aaatttagtt gcaattgtag
     3601 tagtctttgc gatttttgcc tttattaaag ggatatttga actgtttgta cggaacagat
     3661 taaaagagct aacaggatat aaaggaaaga tgcccttaat aatcgggatc atcgatattc
     3721 tagttggcgt ctttttctta ttcaatattg gtgcaggagt cgcagcattg ccttttgttt
     3781 ttgcagtatg gtttattgct gattcagttt tagcgttatt tactgctgac ttggcaagag
     3841 gagtaagtga aggatattat tggtttacga tcatcgtcaa tattttagga attttattag
     3901 gaattttctt attgtttaat ccaatttctt ctgcgttgac attaagcttt ttagttggat
     3961 tctattttat gttatttggt atcacacata tcgtctatgc atttagataa gtaaaatcaa
     4021 acaaataaaa aagccggctt ccgattacag ttttactgtt gtaattggaa gccggctttt
     4081 ttatcatgga caaatatgca cgaggtgatt tttaggtgtc gagacaaatt tatgcaaaaa
     4141 tgtgagaagc tatatacaca aattttatct taatactcga agcatagcgc agttgtcaca
     4201 acctcttttc atataattca ttcaatactg gcaaatcatg gacttcatat ttttctttga
     4261 atgcttggat ttcttcttca gaatattttc ttggatctaa atgcagatct tctactggca
     4321 atgggcgctt gttattgatc ttcacatcga ttactacagg acgatctgat tttgcagctg
     4381 catcaaaggc aaatcgaagt tgcgagtatt ctgtgactgt aaagctattt gccccgagcg
     4441 cttctccaac tttaccgaaa tctgcatctt ctaaaaatac accaaatttc ttttgttccg
     4501 tatcttcttg ttctgcttcg atgaaaccaa aagaatcatt cgaaaagaca acattaataa
     4561 ttggaagctg atatttgact tgtgtaatga tatcttgcat gaccatagca aacccgccat
     4621 caccacttaa ggtaaatact tgtttttctg ggtagcttag ttgtgcggca attcctcctg
     4681 gcacaccatt acccatagtt gcgaaccatc cagatgtcgt atgtttttgt ttaccgttca
     4741 tattcaataa acgaatagaa tggatagtcg tgttaccgac atctgtgacg aaaatcgcat
     4801 cgtcttcagc aatacgattg atttctttat agacagcctc tggacgaatc ggttcttcct
     4861 ctcgatcttc aaaagatttc aaccaattta cccatttttc tttattttct tgatttgcta
     4921 ggtaccagct atcagcaggg cgagcatccc ctaactcgac aagtctttgc aaagctgtgt
     4981 ttgcatcacc gaggatcgac aaagatgttt catggcgtcg tccaaatttt gacgcatcga
     5041 tatcgatttg gataaattca gcagttggat taaaaaatgc acgtccaaat gggaagtcgc
     5101 taccgacaaa taagatcaga tcggcttctg ccaatgcttc atttccgggt ttagtagcga
     5161 cacgtccagc aaaaccaaga aagttttcat aatcatcagg aataattcct tttgctagaa
     5221 cggaagcgac aacaggaact gaaaaatgtt ctgagaattc tttgatttgc ggaaatccgt
     5281 ttcgcgttcc ttgaccaaca taaagaactg gtttttttgc tttttcaaga taaggcaaag
     5341 cagctagcaa atctttttct tctggtaata tcacacttgt tttgtgagtg tgagcggtgg
     5401 agaaaggttg ttcgtcaatt tcttcaaaac caagatcaac agggatagtc acgatagcca
     5461 cgcctttatg ctcataggcg gctttaatgg cttcatctac tacatgcgga agactttgtg
     5521 gtgtcatgac tgtacgattg tatacgctaa catctgcgaa aataggattt tcatttagtt
     5581 cctggaaaga gttatagttc atggatgtag aagcaacttg tcctaagaac gctactagag
     5641 gcacatggtc catctgtgca tcatacaaac cattgatcaa atgtgtcgca ccaggtcctg
     5701 cagagccgaa gacagcgccg actttccccg ttaattttgc atctgcagcg gctgcgagtg
     5761 cgccgacttc ttcatgacga acttgaatgt agttgatttc ggttttttct tgatatagcg
     5821 catccataat tgaattgaaa gatcctccgg gaatgccgta aatatggtcg ataccccagc
     5881 tttcaagaac ttttaccatt gcgattcctg cattgatttt tgacatggtg tttcactcct
     5941 ttagcaatga tgatacataa attttttgta tctagagtat agaacttttt atcgaaaatc
     6001 ccaactaatt cgtcttttca caaaaatgta gtcatgtttt tgggaatatg ctagagtagt
     6061 acatagatag attcaagaga ggggaatggc atggttgaat ggctattgag acttgaacct
     6121 tggcagcaag cacttgctgg gacagctttt acttatttta tgacagctct tggtgccggg
     6181 ttggtttttt tctttaaaga aatcaaaaaa gaagtgctaa acttgatgtt aggatttgct
     6241 tctggtgtca tgattgctgc aagtttttgg tctttgttag atccggctat tacaaaagca
     6301 gaagaaaatg gagatattgc ttggctagtt gtaagtattg ggtttggttt aggcggtgtg
     6361 tttttatata tggcagataa aacactgccc catatgcatt ttggaccaca acatgaagca
     6421 gaaggattgc ctacccattt aaaacggacg atcttgcttg ttttttctat tacattgcat
     6481 aacattcctg aaggtttagc cgtgggggta gcattcggtg cagcagcaac tgcggataat
     6541 ccgacagccg ctatattagc cgctgtttcg gtggcgctag gtattggtat ccaaaacttc
     6601 ccagaaggag cagctgtatc aatcccgttg cgacaagaag gtctgagtcg taaaaaggcc
     6661 tttgtttacg gacaagcttc tggaatcgtt gaaccaattg ctggagtgat tggagcgcta
     6721 ctagtaacga aagtggagct gctgcttcct tatgcacttg cttttgccgc aggagcaatg
     6781 atttatgtcg tggtggaaga attgatccct gaagcacagc agacattgtc cagcaaacgt
     6841 cattttgcag tttttggcgt catgagtgga tttatcatta tgatgatttt ggatgtggca
     6901 ttaggataaa taaaaaaaat atatatgata tatcaaatag ggccgcgaac ttatatcgcg
     6961 accctatttt tttagtaagt tatatcataa tgaagtgaat ggtatcatac attaataata
     7021 gttttttcta tgtgtatttc ctttgatcca gcgaacaagc cagatgataa gtgcgattgg
     7081 gattagaact ttgaccgcaa accataaaag cccgcttagg acactgacaa aaagactgat
     7141 gacgaagcta gctgcaatta gcactaaaag aaccatgaag atatttaaga acatattttt
     7201 ttgacgcata caaaaccctc ctcttgttca ttctttacta tagaaaaagt ataacaggga
     7261 ttgtttaaaa acacctccaa ctgaagactg atttttactt catctactta aatgatcaaa
     7321 caattgcttt ttctctggtt tatcatctaa aatagagcgg aaaaggagga gaatatcatg
     7381 cctaaaaatc gtcttgaagc atttacagat gctgtaatcg cgattatcat gactatttta
     7441 gttttagaac ttcatgaacc taacggagac acgtgggagg cgctcgctgc attaggttac
     7501 cgatttttta tctatattgt cagttttatc attttagcga tttattggaa caatcatcat
     7561 catttatttc aagttgtaca taagataaat ggacgggtct tatgggcgaa cagtttcttt
     7621 gtttttgcgc tttcgctttt tccgtttgca acttcatgga tcagtgagta catcaatagc
     7681 ctggctccag aaatgactta tggttttgtt accttgaccg ctaatattgc gtattatatc
     7741 ttggcaaaag aacttgtcaa agcaaataaa ggccacgaga aagcattgaa ggcgatgttg
     7801 aataattaca agaaatcgta tctatcgatt ggtttgaatg tgttaggaat tgtcttaggg
     7861 tatttagtag cgccagtagc cgtgctgatc gcaaacatcg tgattctagc tgcttggatc
     7921 atcccaagtc gtaccatcga atcacaatat cggtaaaatg atccgtgttt aaaatttaag
     7981 agaaaaatat agaaaaaata aataaacgat caaatatccg agtgatacta gtattcaaag
     8041 agggatgcag atggatcaaa aaagaattca tgtaggactg attactagtt ttgtcacgat
     8101 gcttatttat ttggatcaag gtcatttgac ttggacagta gttggtgtcg taggattttt
     8161 gacattattc acagcaataa aaaaataaac atctttatgt aatctgatgt tctatctatt
     8221 taagaaaagc atgtttacag cagtatgatt ctgttgtaaa cgtgttttta tttgtggaaa
     8281 atttaatttt tagaaaagtg tatcgaaaaa tagatagtta gtttttccac agtggataac
     8341 ttcgtaagag ataaaaataa aaaattagtc aaagaagggc gtatagattt cttttgatag
     8401 gagatataca acagaaatga ataaatatta acgtgttttc aaacagtata aaacggtgtg
     8461 gtttttggaa taaaaaaata acatatctca ttttacgctt ttgttatttt atacttaaaa
     8521 aataacgaca cagaaaatac cgtgtctcag atttctctac tacttctaaa aactactgtt
     8581 tttttccttt gaaatgcctt caaaaagtag gatcaggcag aatatactgg cagaatcaag
     8641 gagaagggag cctaaataag gagaaaaacc atagaaaata taaagtaatt acttataaaa
     8701 caagcttttt atagaaaaat aatatacctg agtagggtat aaattaagac ggaattcctt
     8761 tctagattga gatattgact aggaagaatg ttaagatttt aagcctttaa gctaaaaaaa
     8821 aacccttttt gttaaataag gggaatatag cctgtcagtt tcaaactgca agtcgtcctg
     8881 ctgcaataat atagtagatt agagatgaaa atagattttt ttaaaccaat gactgaataa
     8941 aaagaccgtc atagatacac attggaatgt gtctattacg gtcttttttt acgaacgatt
     9001 ttattgaaga cggacagttc gggtcaaaaa taaaaaagct acgatcagaa ataagaataa
     9061 aatgtatccc aaaataatgg ctagacggtc taacttattt gtcgatagat gtttgtttag
     9121 aagttgatag gcccataaac ctatcagtcc tcctgttgta ttagttatca aatcagtgat
     9181 gtccgctacg ccaataccga ataggaattg aatcaattct gccaagaagc ttacaaggaa
     9241 aataatccct aattttttag aaaaagaaag tctcttgaaa ttgacattca aaagcacccc
     9301 aaaaggaaaa aagacaatca agttataagt ggtctcacgt aataccgtcg tattttcaaa
     9361 agaaaaagta gaaaaaggga cgagattgac attgctgtaa gaataagtga gaaattgtgg
     9421 aagattaaat gatagcttga ataaaatcaa ccataataga aagaataaat aaatccctaa
     9481 taaaaatttt gatacatacc gcatagacat ctcctccatt taaaaagtat accatcgaaa
     9541 accgctgaaa aatcataaaa aagtatgaag tttaaggacc aacgtagtta tcgtacgaaa
     9601 attagaagct tttttttgtt gggaatccgg tttctttaac aaagctaaga tagcgagttg
     9661 cttggaaaag ttgctatctt ttttctgtca aaacgactcg gaatgttcgt tttttgttct
     9721 aatttctcca agttgtttac tttttgatac taagtttatg aaaaatcaag aaatagttgt
     9781 tatactaggt aatgctgaca aacgggattg gcatttcatc ttggttcagc tttttttcca
     9841 attactagga aggagggata gattgttcaa gacttatttt cgtttcaata aaatacaaga
     9901 taatcctttt cgtatcatga atctgatgct acttatcttt attgtattat ggttaggtta
     9961 cataaatcat gattttttga tttcaagttt ttcatcatta gggatcttta cttttttcta
    10021 ttatcaaaac ataccgatga aatatttgct gaaacgtatg tttctgatcg gttgcggact
    10081 gttggttgct ttcgttttgg ggatcttatc gacttatgtt ttatggcttg aaccatttgc
    10141 cgtagctttg gttgcttttt ccagcagatt cgtgttgcga ttattccata tttctaaacc
    10201 aggtggcttg ttttttgcga tgctttctgc catgggaacg agcatgcagc tgccaatcgc
    10261 tcaattaccg atcgtctcac tttatttttt tatgggtgtc gtttttgccc tgattgcggc
    10321 agtgattaca aaattactgg attcacggcc tgagcagaca attgaaaaag caactttaaa
    10381 agaaagattt cacgaagagc ctttagtgat cattgattct gttttctaca gcgctgcctt
    10441 atttctttcc gtttatgtca gtcacggctt gaatctgcat aatccttatt ggttgacctt
    10501 gtcatgtgca tcgattttgc tagcagaaaa cttggatgcg atgaagcatc gacaagtcca
    10561 atatctgatt ggatcgatgg gtgggttatg tgtgtcggca ttcttgtcat ttgtgccgtt
    10621 tacgcagttg cagaccattt ttctgatcac ttttctatat ggaatcgcac aatttctagt
    10681 tgctagaaat tatgcagttg ctaatatttt tcttaatccg atggcgttga tgctatctac
    10741 acttattcgt ggagcatact tgatttcttt gatcgaatat cgttttttag ggatcgtcat
    10801 aggaagtttc atcggtttag gtgttgcgtg ggtaatgacg gttggtttgc aacattattt
    10861 aacggttgtt cgtcaaaaat tagaatagaa ggacaaatat atgtgccaaa agaggttatg
    10921 acaagatttt tgtcacaacc tctaattcaa ggtgttcaaa agccagattc tcagcattaa
    10981 gtcaaattca cacaaaaatg tggaaaggaa ctttcaaaaa aattttatat ttattctatc
    11041 aaaaaatttt gtttatgatg gtaactgaat aaactttcct gagatggtca atgctttcct
    11101 tgaaagtctt acagatattc tttcttcata gaaagtttaa gttttatagt tagtgtacaa
    11161 taaaagtatg tttataccat atggtgtccg gataatcagt catttaaaca atgaggttca
    11221 aagatatgaa aaggggaaat ttgatgaaga aaataagcaa tgaaatccaa attctggcag
    11281 aaactttaac tcttcccaaa gtcgttatag agcaaatgat tgtacaagca aaaaacatcc
    11341 ttgatgaggt gtttgagcaa tatagtcatg aactaatgga tcctaataaa gcaaaggcga
    11401 ctgcaaagaa aatagacaaa gtctatgaag aggaaccttt tgcagcatta gctatttatc
    11461 tatatgcagc ttctcaaagt tggaaaaaaa tttatcaacc attgaagatt ccaagaacta
    11521 tctatttggc aacaatgaat gcttttacta gatttattca tgaacatttc caagtaacag
    11581 gaagctatcg ctttgaccgt ggtttttgga tttggcatta cactagtggc ttgatctttc
    11641 ggattggtga attggagtac gaaatgacat attttccgaa agggtacacg gatctaagat
    11701 tagaaggaaa gcagtgcctt tctcttcata ttccttccga tgcagattta tctcagaata
    11761 agataagaga tagttacgaa agtgccattc gtttttttga actttatttt cctgattacc
    11821 attaccaagt gatgtacaca gatacttggt tactatcacc caatcttact aaatggttga
    11881 aaaaagagtc aaaaatctgt ctttttgcag ccgattatcg attattatca gttgatgaac
    11941 aggacgatag tggagtccct tggatctttg gacgagtaga tgcccaaata catgattatc
    12001 cagaaagtac gagtttacag cgacaagcaa aagagcaatt gcttgcaggc gagcacattg
    12061 gctctggctt aggtattctt acttcataag tttagtactt cgaaatagtt taaaagagcg
    12121 tgagacaaaa gtaaagaaca cttttgtctc acgctctaaa cacgtataaa cggcggaagc
    12181 agaagcaact ccttcggaaa taagctgaaa ttcacaaaaa tttgaaaagc aattttcgtg
    12241 aatttcttct tatttcttgg agttaaacgc ttctgtccca gcctcttttt tagtgttcta
    12301 tcgaacacac agtacgttca ataggtaaac tagctataac aatagatatt aaagttaacg
    12361 gacaagaggg ccttttttag gtagctaaaa cgtaataatg aaaatttatt tccagagata
    12421 ggagtcaatc agctagtctg atcgactgtt ttaacaagtt gactttcatt ttaacttttg
    12481 ataccattta aaacacaaat cgtaattgtt tcgatttgtg ttttttagca tgactacaat
    12541 caaagaagaa agtgggtcgt ccatatggaa aaaacagata tctcaagtgc ataccgccgc
    12601 ttgaaaagcc caaatatcaa aacacgaaaa cgtgcgctga agatcatcaa agatgtgaaa
    12661 cggaatagtg ggaaaaggta agaagaagga aacttaatta aaaaaatagc cgaaaaacgt
    12721 ttttcggcta ttttcaataa tcggtttttg tgtaaggttt ccgaaagaac tgctgttgat
    12781 tttccatttt taacatatga taaattggta gaatctttct tttcaaattg ataccattcc
    12841 ctaattccag ttatatagtt aactacagaa ccacaaagca cgtacgttta taaaagtatt
    12901 atctgtagtt atttttcaat tccctttcaa cctcttattt tgaccagtag tattgatcac
    12961 tttacctttt aacacctttg ttcgtttttg aaacattttt agtcaagaat ggaaacgtaa
    13021 ctacataatc aaaggttttg cgaaatattt catgaaatat ttcatgtaga agcgagcaat
    13081 acggttgcaa ataaccatta tcgtttaata agcagttacg aaagctccca atatctctaa
    13141 cgttcagctc actccatttc ttttcttcaa aaaaatcagt gattcgtatc tctttctatt
    13201 tgtcgaaaaa gttaacttta aaaagtaacg ccgaaaaaat atgcaaaaaa ataaaaaagc
    13261 agttactatt gctagaataa catcaaggaa taataagttt tggttttcag ataatagtcg
    13321 ataagttgtg tattggaatt ttagatacag taataaagta tttttcatga aattttgtga
    13381 gaatcactat tacaagtatc tttaataaaa ttaatggtta aggaggaact taaagtagaa
    13441 tgtaaatgaa tagttgtagt cagtcgattg tgatactaga ctcaaagttg caggaataag
    13501 tttttcaatt tgtgattgga agataaaaaa tgaaaaagaa gggctttttt ttatactttg
    13561 ttgattgtag tgtttatttt ccctctgttt agccaagtaa cattttctat gactcaacca
    13621 gtttcaagtg aggaacatga taaccttttt cgtgctacag aagagtttaa gaaatatcag
    13681 gaaaatattg ttccggagac tccattagct agtgagccaa ttactgatat tgatggaaac
    13741 caaataggat ggtatataca gtacgaagtt atggtggtaa ataatgactc aatagtaaaa
    13801 aatacagtag gcttagagct aacaccgatt gaaaaggtga gttcattgtt aacgtatatt
    13861 tatactgatg aaagtgacga gactgagatc attttaacgg attactcaaa aattgctact
    13921 gataaaaagt atatattgtg gatgtagaca ctagtgaaat actttatgat atagaaattg
    13981 atgaaaattt actagatgta gcacaagaaa tcgatcatca aaagcaggaa gctattcgat
    14041 atgctggtag aaaagggaaa agaaaatatt tattacgtga atgtagcaaa agttagagaa
    14101 gatgaaaatg agtggaaaga attcaagagt cgctactcaa ttaactcgac tccgacattt
    14161 acagtttaca gagaaggatc gatagaaaaa actgtttttt ggactaaaga aagtggaatg
    14221 tctttagctg aagtagaaga gtttttggat tatgttagta tgcaacagta agggagttct
    14281 tattatgaaa aattttgaca catattatgt tattgttttt tcgatatctt tgctgttaat
    14341 attactaact ttaatgcagt ataaagagta tccagagtat tttattttaa cttttgtata
    14401 tttagtaagt agctacacac ttctatataa attcagaagt tcttctagag tttctaaagt
    14461 ttgtttctta attagcttat tgattctata atatttttga tttatatagg aaattaaaaa
    14521 tattatagaa tcaacactca gagaacgggt tggtttttaa tagatttaat aagtactgat
    14581 aatgaaattt ctcctggttg ggaaaacgaa gttggttacc ctgtagaaga attttttcaa
    14641 gattactttg cggagtatgc cgataggata atgagagatt acgtaacaga taaaactcaa
    14701 gaagtcatca atcaatccca gtcattaaat gaattatctg ataaggcgaa agaagaagca
    14761 gttgccatta tttcttcagg gattagtgac tatattgata tgagtggtga aatcaattat
    14821 ggcgataaag acaaaattgt acgcatgata aaagctttta tcaaaacttt tgatgtgaag
    14881 gcagatctta agtttaatga tacttaccta gtaggaaaat taattaatat ccttgggaca
    14941 gagaaagata cggaaacgtt tatttcctct ttgtctatgt tgtttacaga taagcatttt
    15001 tcaactcagc ttggtggaga ggaactagtg gaaatctttt aaccattacg cccagcatta
    15061 ataaaagtat atcaaaaaag tactcctgat gatttttaag attggtttga gaaataatgt
    15121 gaaaacacta tttttaatgt taattataga tagagatgaa cgcgtcatat ggttaaaaga
    15181 atgaaaaagt caaagataca ctgctatatt tcactaagga tatagcagtg tatctttcat
    15241 gtcgtttcac tggcagtttt ttataaaagg aggtgtgcat ttcagttgct tttctttggt
    15301 agttagttga atcgtttaag aattaacgga tgtggcagac aggtgctctg tccaaaaacc
    15361 agtaaaatct ttgatggttc catctttatt tagctgtgcc tgttcaaata ctgttttgtt
    15421 tttaccgaat ggatcaattg caataattgt tccgatcccc gcacgtttgg cagcaagtaa
    15481 tcctgagtaa gcatcttcga taacaagaca atcagccgga gctaagctca gtttgtctgc
    15541 cgctttaaga aaaatatccg gttgcggttt cccagggaaa gagccgtcgt catagacaat
    15601 cttgtcccag tcaaaccagc gggctaaatc gaaaatatca aaataaaaag caacattctc
    15661 tttgacagta gccgtggcaa tcgttaatgg aatctgttgg tcagtcagct ggtcaagagt
    15721 cgcttcaagc ccttttgtca actgaagctc gttttcattt tgcaagcaaa gcatacgata
    15781 atagctttct ttttcttctg acaatacggc gatctcagag gcggtcaaat gctctgaaat
    15841 gaaatgtttc aaaatctccg tattcgtccg accatgaata ttttttaaaa tatcctcgtc
    15901 tgataaacca tcttttgtat gatcatgtat catatgcagc caagcagctt catgcagatg
    15961 agagtccaaa aacattgttc cgttgaaatc aaatataatc cctttcatag ttacgctcct
    16021 atagtggtat tttcggttga atcagcaatt tgcagatcga catattgtgc atagtgctct
    16081 tgaacctccc gcgagatctg gcgatccgta atgagcagat cgaaatcatg caaattataa
    16141 aacacataaa aatcatctcg attgaatttt ttattatcaa cgagtagata tttcttacgg
    16201 gaattattta gagcgatctg ctgtgcttct ccttcttcgg tactgtaagt agagatcgct
    16261 tcgttgtgaa cgccatttga actgataaat gcttttgtaa actttagtct tcttaaattg
    16321 tcgttggtga tcggtccgac aaatgcgccg gtatttttcc ggaaatcacc gccaatcagt
    16381 agaatttctg gtccatctgc ttgagcaaga atatcaaaaa ctggataatt atttgtaatg
    16441 atccgaattt tcttgttcag taaatgcgtc gccaatagtt cgattgttgt acctggtcct
    16501 aagaaaatcg tttctccctc gtgaatcaag gaggctgctg tggcagcaat ttcttttttt
    16561 tcttgaatct gcagagtggc tttttcagtg tgagaaagtt cttgatctaa agtgtaggaa
    16621 agactttgag cccctccatg gacacgcagc agcttgcccg atttttctaa ttcatctaaa
    16681 tctctgcgaa cggtcatatc agaaacatct aattgattga tgatttcatt aacggtaagg
    16741 attccttttt tattgaccat ttctacgata gtaagcaatc tttctttttt caacattgtc
    16801 ttcacctcta atttaaggat aatctatcat ataaacggac aacagtcaat ctaattcgaa
    16861 caaaagtaaa catttagggt ggtttttatg tttgttacaa tagattttat tgctgttttc
    16921 tggtttttat gattatttgt gtttgttttt gttgacaaat gttttggatg cgtttacaat
    16981 gcaatcagtt agaaagagcg aaaactgatt atagatttga ggagagatgt acatgcttaa
    17041 attaccagaa gattttattt ttggcggagc cacagcagcc tatcaggttg aaggagccac
    17101 taaggaaggt ggcaaaggcg ctgttgcttg ggatgacttt ttagaggaac aagggcgatt
    17161 cagtcccgat ccggcaagtg atttttatca tcaatatgca aaggacattg aattgtgtga
    17221 acgttttggt gtaaatggtc taagattatc cattgcttgg agccgcattt ttcctgatgg
    17281 agctgggaaa ccaaatccag aaggaatcgc tttttatcat cgtgtgttcg aagaatgtaa
    17341 gaaaagaaac gtaacgccgt ttgtgacgtt gcatcatttt gataccccta aacgtttgtt
    17401 tgaccatgga gattttttga atcgagaaac aatagaagca tttgtttcct atgccatttt
    17461 ttgttttcat gaattcaaag aagtcaaggt gtggagtacc tttaatgaaa tctatccagt
    17521 tgcaaccaat caatatttgt taggtgtttt cccaccagga atcaaatatg attttacaaa
    17581 gatcgtcgcc tgtcttcata atatgatggt tgctcatgcc cgtgtagtga actatttcaa
    17641 agaaaacgaa cttccgggtg aaattggtgt agttcactca ttagagacga aatatgcggc
    17701 aacagacgcg ccggaagata agcatgctgc ctttttagac gatgcattgt cgatccgttt
    17761 cttattagat gctacctatt taggctatta ttcaactgaa accttgactg ctcttgatga
    17821 gatatgtgaa gcaaatcagg ccagctatca ttttcctgaa gaagatttcg ttgaattgaa
    17881 aaaagcatcc acgcgtaatg actacttagg gatcaatcac taccaatgcc attttgtcaa
    17941 agcttacgat ggagaaaatg caatccatca taacggtacg ggtgaaaaag ggacctctgt
    18001 ttataaagtg aagggaatcg gagaacgtat ttataaagaa ggaattcctc gaactgattg
    18061 ggactggctg atttatccag aaggtctata tgacttgttg ctgcgaatta aaagcgatta
    18121 cccacattac aacaaaatct atatcactga gaacgggatg gggtataaag atcagtttga
    18181 agatggcatt attatggatc agccgagaat cgactatttg agagtctatt tggaatcctt
    18241 aagcaaggcg ataacagccg gggtaaatgt gaaggggtat tttttgtggt cgcttatgga
    18301 tcttttctca tggacaaatg ggtataacaa aaggtatggc ttgttttatg ttgattttga
    18361 aacccagaag cgttacccaa aagaatcagc ttactggtac aagttggtca gtgaaaccaa
    18421 aacgattatt taataagtga taatggagga agaaaagatg aataaagagg aattacaaat
    18481 gcttggtttt gagatcgttg catattcagg cgacgctcgc agtacattat tgaaattatt
    18541 gaaagaagta agacaaggaa actttgaaca tgttgattcg gcgttgaaag aagccgacga
    18601 aaatttaacc cttgcacata attcgcaaac aaaaatttta gcggaagaag catctgggaa
    18661 agagatggag atgggattca tttttatcca tgggcaggat catttaatga ccactttatt
    18721 gctgagagat ctgattcaag actttattgt actgtacaga cagaatcaag gataggagaa
    18781 gaacgctatg gatggaatca ttaaacaaat cgaaaaaggg aaaccatttt ttgaaaaaat
    18841 ctcacgtaat agttatttag gagccgttcg tgacggattt ttaacagcga tgccagctat
    18901 tttattttca agcattttca ttttgattgc tgcggttcct gagatttttg gttaccaatg
    18961 gcctgaatct gtctccacat ggctatggaa agtctataat tattcgatgg gtgttgtagg
    19021 gttactcgtt tcagcaacca ctgctcgctg cttggctgat tcgatgaatc gtcgcttacc
    19081 gaaaaacaaa gtaatcaaca ccacctctgt gatgctggcc tctgtggtaa gtttcctgtt
    19141 gttaagcgtc tctccgattg aaggtggatt ttcaacggaa tatatgggga caaagggact
    19201 actggcttcc tttgtcgctg catttttaac agttaattta tataagtttt gtgtgctgaa
    19261 agatattacc attaaaatgc ctaaagaagt tcctggaacg atttcgcaaa ccttccgaga
    19321 tatttttcct ttctcttttt cagtatttgc ggccgtttta attgatttag gcattcgaca
    19381 aatcttccaa atctcatttg cagaagcaat cattacggtg ctgcagccgc tatttacagc
    19441 agctgacggg tacttaggaa tcgctattat ctggggagcg atggcgctgt tttggtttgt
    19501 cggtgttcat ggaccgtcga tcgtggagcc ggcaattgcg gcaattatct atgccaatgt
    19561 ggaaaccaat ctgcaattgt tcaattccgg tgaacaagct tctaaagtac tgacggtggg
    19621 tttagggaat tttgtaggaa ctatgggagg aactggggca acattggttg ttccttttat
    19681 cttcctactc tttgctaagt ctaagcagtt gaaggcagtt gggaaagctt cctttattcc
    19741 agtaagtttc gctgtcaacg aaccattgct atttgcggca cccatgattt tgaaccctta
    19801 tttttttatt ccatttttgt taacacctgt tgtaaacgtt tgcctgttca agttttttgt
    19861 cgatgtattg ggcatgaaca gctttatgta cgttttgcct tgggcaactc cagcaccgat
    19921 cggtttggtt ctaggaacgg gcatgggtat cttagctttt gttctagcag cggttctaat
    19981 cgtcgttgac ttcctgatct atctaccatt ttgcaaagca tacgatgctg tcttagtaga
    20041 gaaagaagca caaaaagcag aggtgatcgc aaccgaggaa ggtgcttctg ccgatgtacg
    20101 tgaggaagta cctgtggcag cgagtcaagt tatcagcgat gcaaataaag aaatcaatgt
    20161 gttggtactt tgtgctggcg cagggacaag tgcgatgtta gctaatgctt taaaaaaagg
    20221 tgcatctgaa tcgaaagcac cgatcagtgc aatggcgggt gcttatggtt ctcattacga
    20281 aatgctgcag gattttgata tggtggtctt agcaccgcaa gtcaattctt actatgatga
    20341 tatcaaagaa gacaccgatc gcttaggaat caagctggtt gcgacaaaag gagcagaata
    20401 tatcggatta acgagagatc ctgaaaaagc tgttcagttt attctgaacc aatttcaata
    20461 aaggaggagc cataatgaaa atgggaattt ggttgcgtaa agctgtttta tttgcagctg
    20521 tgttaggggc tttgggggct gtttcaaaaa ctgttgaagc atctgccagc gaatttattc
    20581 gcggagcaga tatttcgatc ctgtcagata tggaaaaatc tggtgcaaaa tattatgaag
    20641 acgatatttc aaaagatgcc ttagagattt taaaaaataa tggtgtcaac tatgttcgac
    20701 tgcgtttgtg gcaggatcct tataatagta atggagaaag ttatggagca gggacaaatg
    20761 atctggaaac gacgattgac cttgcaaaac gagcaaaaaa tctgggactt aaggtgctgc
    20821 tggattttca ctacagtgat ttttgggttg atcctgggaa acagaatctt cctaaagcat
    20881 ggcaaggtct gacctttgaa gaaatgaata cggcattgta cgactataca aagaacgttc
    20941 tgtcggaaat gaagcagctg gacgtttatc ctgatatggt tcagatcggc aatgaactga
    21001 atagcggaat gctctggcct tatggcaagt cttggggaga aggcggggga gaatttgatc
    21061 gattggctgc ttttttgaag tctggtatcc aagctgttcg agacactcaa cctaaaacaa
    21121 ctccagtaat gctccactta gctgatggtg gcgatacagg agcatttact tggtggtttg
    21181 atgaaatcac gagtcgaggt gtgtcatttg atttaattgg agtgtcgtat tatccgtatt
    21241 ggcacggttc aatgaatgaa cttcaaacca atatgaatgc gatcagccaa cggtatggta
    21301 aagaagtgat cgtagttgaa acagcttatg ggcatacaac agcgaatgcc gatactatgc
    21361 caaatgcttt tggtgaagcc gaagcagctg cggggggata tgaaccaaca ccgacaggac
    21421 aagcagagta tttgctggat cttgccgatc ggattcaggc agtaccgaat aatcgcgggg
    21481 cgggcttctt ctattgggaa cctctttggt acaacggaaa tgtgagttgg gcaacacaag
    21541 caggtatgaa ttatctcagt gttcaatcca ctatgggaaa cgaatgggac aaccaagcga
    21601 tgtttgattt tgctggaaac gccttgccaa gcttgcgtgc gtttaaacaa gcaggggcgc
    21661 aaataaatct agttaaaaat gcaagtttcg aaagcgatgg accaacgacc agtccttcca
    21721 attggcaaac ctggtttcaa caaggaaccg ctaagggtac gatcaaaacg gaagcgggca
    21781 ctttttttgg ggactacaaa ctaacttttt ggcaggatca agcatacgag gcatcagctt
    21841 atcaaaatgt tagtggcata agcaaaggaa cttacacatt gagtgcctat gtaatgtctg
    21901 ggggagagtt tgatactaat cagttatata tcaaaaatta tggtggagcg gaactaaata
    21961 ctgcggttgt taaaacaagt gaatggacaa aaattacaat caaagacatt ccaattacaa
    22021 caggtgtttg tgaaattggg gtttatagca aggcttcagg aaatgcttgg acgaacgttg
    22081 attttgtttc attggtgaaa caatagactg cggatcgttt cgattcaaga tcggaggttc
    22141 ccttcagcca catcgttagc gtagaaggca ggaatcgaac ctgcacctcg cctttgccaa
    22201 aaataaccag aaacgatttc cagtcatttt taccaaaacg agtaaagcac cagacttcat
    22261 ctacactttg tattatgcta aagagagttc aacgatttcg taagaagcaa tgaaaaaatt
    22321 gcaaaaagtt gtgcagataa cataaagttt gtttaagaaa gggtaacctt agaattccgt
    22381 cgtgaatatg atttgagcac ttagatggat agaaaaaagt tctcggaaaa cagttcgttt
    22441 ttcgagaact tctttttatg ataagaatga aacaaattaa cttatattat agtctctttt
    22501 ggtagggaac catcttattt ttaatgaaaa tcaagcattt tagctattga agaatgttga
    22561 tttataggga ttccccctcc at
//
LOCUS       DACDLM010000048        21393 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.048, whole genome shotgun sequence.
ACCESSION   DACDLM010000048 DACDLM010000000
VERSION     DACDLM010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21393
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.048"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            185..1183
                     /locus_tag="IV356_001845"
     CDS             185..1183
                     /locus_tag="IV356_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP9015533.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1295..1804
                     /locus_tag="IV356_001846"
     CDS             1295..1804
                     /locus_tag="IV356_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HAP9015534.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(1834..2493)
                     /locus_tag="IV356_001847"
     CDS             complement(1834..2493)
                     /locus_tag="IV356_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HAP9015535.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(2495..3259)
                     /locus_tag="IV356_001848"
     CDS             complement(2495..3259)
                     /locus_tag="IV356_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HAP9015536.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(3267..3944)
                     /locus_tag="IV356_001849"
     CDS             complement(3267..3944)
                     /locus_tag="IV356_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HAP9015537.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(3981..5366)
                     /locus_tag="IV356_001850"
     CDS             complement(3981..5366)
                     /locus_tag="IV356_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HAP9015538.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(5576..5660)
                     /gene="ffs"
                     /locus_tag="IV356_001851"
     ncRNA           complement(5576..5660)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="IV356_001851"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="IV356_001852"
     CDS             complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="IV356_001852"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HAP9015539.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            6305..7162
                     /locus_tag="IV356_001853"
     CDS             6305..7162
                     /locus_tag="IV356_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HAP9015540.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(7243..7578)
                     /locus_tag="IV356_001854"
     CDS             complement(7243..7578)
                     /locus_tag="IV356_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015541.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(7645..9015)
                     /locus_tag="IV356_001855"
     CDS             complement(7645..9015)
                     /locus_tag="IV356_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NOL1/NOP2/sun family putative RNA methylase"
                     /protein_id="HAP9015542.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(9093..9629)
                     /locus_tag="IV356_001856"
     CDS             complement(9093..9629)
                     /locus_tag="IV356_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP9015543.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            9938..11419
                     /locus_tag="IV356_001857"
     CDS             9938..11419
                     /locus_tag="IV356_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAP9015544.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTTKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHKLYMKKGYENKTKRM"
     gene            complement(11522..12229)
                     /locus_tag="IV356_001858"
     CDS             complement(11522..12229)
                     /locus_tag="IV356_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HAP9015545.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(12308..12646)
                     /locus_tag="IV356_001859"
     CDS             complement(12308..12646)
                     /locus_tag="IV356_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HAP9015546.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(12757..13719)
                     /locus_tag="IV356_001860"
     CDS             complement(12757..13719)
                     /locus_tag="IV356_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HAP9015547.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGL
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(13734..15065)
                     /locus_tag="IV356_001861"
     CDS             complement(13734..15065)
                     /locus_tag="IV356_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAP9015548.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(15073..15753)
                     /locus_tag="IV356_001862"
     CDS             complement(15073..15753)
                     /locus_tag="IV356_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HAP9015549.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(15972..16451)
                     /locus_tag="IV356_001863"
     CDS             complement(15972..16451)
                     /locus_tag="IV356_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HAP9015550.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            complement(16578..18257)
                     /locus_tag="IV356_001864"
     CDS             complement(16578..18257)
                     /locus_tag="IV356_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAP9015551.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            18805..20307
                     /locus_tag="IV356_001865"
     CDS             18805..20307
                     /locus_tag="IV356_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9015552.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            20320..20982
                     /locus_tag="IV356_001866"
     CDS             20320..20982
                     /locus_tag="IV356_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9015553.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(21083..21286)
                     /locus_tag="IV356_001867"
     CDS             complement(21083..21286)
                     /locus_tag="IV356_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAP9015554.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
BASE COUNT         6354 a         4435 c         3635 g         6969 t
ORIGIN      
        1 atttgcatac ttcataataa taataacata atacctaacc tctcgtaaaa atactagatt
       61 tgttttcttt tatttttcat cactagatac attctataac ttaccgtttc gatttcgaat
      121 tcaaacattt ttgagaagca ttctcaatta aattctgcta tagtgtgaaa agggaggaat
      181 ttttatggaa atctatgaca ttacaatcat cggtgcaggt cctgtaggga tgtttgccgc
      241 tttttacgca ggaatgcgcc aagctaaaac aaaaatcatt gacagtctac ctcaacttgg
      301 tggtcaatta gcaactttgt atcccgaaaa atatatttac gatattcctg ggtatccagc
      361 aataaaagca agtgaattaa tcgatcaatt agaaaaacaa ttaactactt ttaaccatac
      421 attccattta aaagaagaag ttctctcgct tactcgtgaa gacgaagtta tcgagattac
      481 tacaaataaa ggcatccatt attccaaagc agtcatttta gctttaggaa atggttcatt
      541 ccagccaaga aaattgaatt tagataatgc tgaatcattt gaaaaccacg gattggatta
      601 tttcgtgaat gatttgatga agtatgctgg aaaaaaagtc gctattgctg gaggtggtga
      661 ttctgctatc gattggacgt tgatgttaga gcctattgca agcgaagttt acttgattca
      721 tcgtcgcccg gaatttcgtg cgcacgaaca tagtgtatca cgcttgaaat cttcatctgt
      781 caacttgctt actccctatc tcatcgatgg attatcaggc aataatgggg aactgacaga
      841 tatccggtta aaaaaagtga aaagtgacga gacgattgat ttgatgattg attctctgat
      901 cgtcaattat ggattctctt ctaatttaga acatctttct tcttggggac ttgatagtac
      961 cagaaatgcc attactgtaa aatcagatat gtctacttct attccaggcg tttatgcagc
     1021 tggtgacatc tgtacctatg aaggaaaagt gaaactgatt gctactgggc tcggtgaagc
     1081 acctactgca gtgaacaacg ctttacacta tattaatcca aaggaacgaa ctcagcctgg
     1141 tcacagcaca agcttatacg ataaaaatct tcgtcctagt tgatttttta tatctctttg
     1201 catttcaagt taaacccgaa agcagtttct tgcatttttt tcatgttccg ttaacatgaa
     1261 atagagaaag aaaaaataaa gggggagcaa taatatggtc gtcaaaactg agactttaga
     1321 agaaaaggca agagaactat tgaaggaacg tggcgtaact gtagaagata tcgcacaact
     1381 tgtcatgttt ttacaaaaag actatatttc tgatttgact ttggcggatt gtactgaaag
     1441 tgtcaacagc gtgctaacaa agcgtgaagt acataacgcc attatcactg gaatccaatt
     1501 agatatatta gcagaaaaga aaaaattgat gagtccgttg caacatatta tcgaagatga
     1561 cgaaggcctt tacggtatcg atgagatcct agccttgtca atcgtgaatg tttacggtac
     1621 gatcggcttt acgaattatg gttatatcga caaggtgaaa cctggtattt taaaagaact
     1681 aaacagccac gatggcgttc atgtccatac cttcttagat gatatcgtcg gagcgatcgc
     1741 cgctgctgct gccagtcgat tagcacacaa agaaccagaa aaaagaagtc gccttactca
     1801 ataattcaac aaaaaaagaa agaaaacgtc tatttagacg agttctttct tttttgtttg
     1861 tttcaagcta ttttttccta agaaaagaaa aacagcaaaa aataattcta ataatacaaa
     1921 aaataagata aagctatgca tgaaaaattc ttctggaagt acattgatga ttggatcagt
     1981 aacgggatcg aataaccagt catcgttgtt gaaaaacgtt tcatgaaaaa ggataaaaaa
     2041 gcgatcaaat cctatcatca tgaaaaaacc gaaaacaact ggcagtaaca tgccgatttg
     2101 aaacggacga atcaaccgcc aaagccgatc attcttttgc aaatatttga taaacaaaat
     2161 actcgggatc aaagtgatga aaaacacagc ataatccact aaaaacaaaa ttttcacttc
     2221 ataaaagtga tgggctccgc tagcagaaac tgggaaatct ggcaagctga ggatggtttt
     2281 gaagggatta ttgagataat tcattaggtg atcaaaattt ttcagtaacg tctcttgatc
     2341 taaagaagta taatccaaaa tttgcaaatg tccgatatca aatacgtata gtggtcgaaa
     2401 gttgatcgtc acaccaactg ccagactgat cagtgtcaga aataggctga acaatccagc
     2461 atattccatc cactgccatc tcgaattttt catattagaa gctccattca tccagtgatt
     2521 gtttcacata ggtagctggg ataggcaacc caggtacatc ttcttctttt gtaaaacctg
     2581 ataaaacgag caaagtatct atattattgc gtatcccagc ttggatatct gtttcatagt
     2641 tatctccaac catgattact tcttcttttt gcagccctaa tacttcaacg gctttatcca
     2701 taatgatggc ttctggtttt ccgatgtaga tcggcggcgt ttgggttgct gtctctacaa
     2761 aagagatgac tgaccctgct ccaggaagaa ggccgcgttc agtaggtata ttcttatctg
     2821 ggttcgttcc aatgaaagta gcaccttttt gaatagcaag tgttgcttta actacttttt
     2881 cataggtcag ataattatct aagcctacca ctacatagtc aggagcctct tcttcccatg
     2941 taaatccggc agctaaaatc aagtcaatca atcctgcttc tccgataaca tagacttttt
     3001 tcccttttcc atctgctttc ataaaatcga ttgttgccaa agtagctgtg tagactgtct
     3061 ctggagctac atgaatgtca aactcatctg ctagacgatt agctactgtt tctggtgact
     3121 tagtcgtgtt attggtaaca aacaagaaag gtaattttct tttttgcaat tcttccacaa
     3181 atcgtttacc ggccggtatg ggttgtgtcc cacgataaat cgttccgtct aaatcaatta
     3241 aatatccttt atagtccatt catccactac tcttcccttt ttctgatcgt aaatgctgtt
     3301 tttgtttttt ctacttgttt aggttgttct tgttttttta ctttttcaga ggtttttgct
     3361 gactctgttt ttcgattttt aataaccggt tttttgcgat tagatgcgac tggtcctttt
     3421 ttctcatcga tatacgcacg attatggttt tttttctttt ttcggcgctg agttgtcttt
     3481 tcttttttac cgccgattct ctcgatgaca aaatacgcac aaccaaaatt gcaatattcg
     3541 taaagatagt cttccaagga atcgattcgc tgatctggat gcgcccgtcg attatccgct
     3601 tggaaaaatc cttttaggcg tagttgttca taaccccaat ctcctacgat ataatcatat
     3661 cgggctagta catcactgta acgttctcca agcttttctg cattaaatcc ttcacgataa
     3721 tcggacacaa gccgataatg tctttcacct atcaaaaaat tactgtcatc taacagtgtc
     3781 actagctcgc ctttgacttt ttctgcttta ggctcctcaa cgatttcttc caaagcagct
     3841 gtcagttctt cggtgactgt tgtttcctgt tcagctgatg attttttctt agcaatttct
     3901 gttttatgct caacgttctg ctgttcattt tgttttgcag acatgcgttc accacctatc
     3961 ttttttatta taccttgttt ttatttgatt gggtagtgag ctttcaagta atctcctacc
     4021 acacttcgga taaattcagg gaacaaaaat tcattttttc cagcaatctc aatcgttgga
     4081 aaaaatggaa caaacatcaa atgatctacg gtagtaaaag tataattttt attcagatcg
     4141 attggcttgt tcttccaaaa gacttgatgg ttaatagaat catatgtgat tccattatag
     4201 accatctgcc caaaaatctt accgcgaaat cccattccct tcataggata gttacgtaaa
     4261 aagttacgat ttttttctat ttctaaaact aagcggatca gatcatttcc acccaatgtg
     4321 acatttaaca agtgcatcgg atgcggcaac gcagtgtgaa gctgatcctg attgacccgc
     4381 ccttttggaa tttcagttaa aaacagacca ctgtttaata ttgctgcttc cgtctttcct
     4441 cgttctttca ccgcctcaaa ggctacttgg ataaacgaat gctcattgaa gatatctaga
     4501 ctcagagaaa atggcaaatc tgctacttct ttttctttta ataattcatg cccacgttct
     4561 agataactat ttatttcttg ttcatcttct gtaaaagctg tcattgtttc ggtagggatg
     4621 gctttggctg aatgcttaag gatttttttc tcttcatcga tggttaaatg gacttcaccg
     4681 acatactgcc cgtactttcc agcggctgct atttggacat cattgattac gtgaccttct
     4741 ctgaataaat gatgggtgtg cgatcctaaa ataacatcaa ttgctggtat ttcttttgca
     4801 atttggaaat catcctgaat cccgagatga ctcatcaaaa ctaaaacatc cacttgtgaa
     4861 cgtaaatctt cgactaattc tggcaaaata tcataaggat tccgtatgtc ccagccattc
     4921 ggattataag taagcggaaa tggagcagta aatgcaatta gtccgatttt cgtctggtgt
     4981 ttcgttgtaa tgattttata tggtttcgtc catgccggtg gctggagcgt atttttatcg
     5041 aataagttat ccaggatgat atcaaactca gcatgatcgt ataaatgatt caactcttct
     5101 ttggaatttc ctacgccttc attgtttcct atcgtcgctg catcataacc aacttcattc
     5161 atcagcaaga tattttcctg tccattcgtt gcttctgaca atggatgcca acgatccaca
     5221 aaatcaccta gatctactgc aatcgttgtc gttttttctt tcttttcgtt ttctcgttta
     5281 cgttgatcca aaaaccttct gatccttggc caattttcta aatgagaatg cagatcattc
     5341 gtatgtaaaa tcactatttt ttccatgtac cctctcgcct ctctttatct ttatcatacc
     5401 ataggcagct ttttcttcca ttgaaacaag ctctatttca gagtttttcc tgccttgaag
     5461 caaattgtat aagtacaata ttcgataaat cagtctggct aaaaaatcag gaacattcat
     5521 ttttacagta ctataaaaat aaaaaaaaca gacccgaaag tctgttgtcg tttcattata
     5581 atcagacaca tggcggaacc tgcttagtgc tgcttccttc cagacctgac acgcttcaca
     5641 agcccaccat tgtcctagcc tttcggcaaa gaatagtata ccttattttt cattcgttga
     5701 ccagtctttt tttaatttct tttttcgctg gcggagcttt cggaaaaagt cagtcaaaat
     5761 catcccacat tcgtcttcta aaatgccacc ttctacatat gcttggtggt taaaccgctc
     5821 gtcctccaaa agattcatca aggtaccggc tgttccgcct tttggatcat acgcgccgaa
     5881 ataaacttct gctacacgag acaaaatcat cgcgccgctg cacataggac aaggctctaa
     5941 ggtaacaaaa agtgcagcat cttccaagcg ccagcttccc actttttcac aggcttcctt
     6001 gattgcaagc atttctgcat gtgtagtagc atcttgcgtg gtttctctaa ggttatatcc
     6061 tcttccaatc acttttccat ccaatacaac cactgctcca atcggaactt catgaagcat
     6121 ttctgctttc tttgcttctg ccaatgcaag gcgcatccat ttttcttttt ctactgcatc
     6181 aagatttgta tttaccaatt acccttccct gcctttgttt tttcttgttt tactttagca
     6241 tatgataaaa aggctgtaac taactttttt ttctatggta aaataaatac aagaggtgaa
     6301 caagatgaaa atggataaat tacttgctct ttacccacaa gcacagaaaa aaaactctcc
     6361 agcatcagaa gcggatatcc tttcttttgc aattgatgat gcttttatct ggatcaaaca
     6421 agattcatta tctcaacaag aaaccagcct tttgaaagcg ttattccctg taatcaacga
     6481 tcaaaaaaaa cacccatggt atcactatct ttttaaagat gcttcttgtg ttcaagaaaa
     6541 aagctttcgt ttgatccagc ttcacgtcga atcaaaagga gaattcttaa aaaaagaatg
     6601 gcaagatact attttggaat tatttcgcta ttctgctgat ttcttttttt atacagacac
     6661 agatgcgctc ttagtcgaac aaataaaccg tgattatctt gatgctactg aaatcaacgg
     6721 tatttttcta tctttagatg ctgattttga tacgacaacg tctgtattcg ttggttcttt
     6781 ccattcacct ggcaccgacc tcgtcccttt gtttgctgaa gaaagaaaaa tttttttaac
     6841 agagcaaaac aatctttata ctcacagccg tactttttct atgcaagatg tggctttaca
     6901 ttactataca aaagatactg taaaagatag taagttgatc aaaagttaca tagaactgat
     6961 caaacaaaat gaaatggaag tgatcattca agaattatgg aatgaattag gcaatgtcag
     7021 ctctgctgca aaaacactgt ttcttcatcg taatactcta aaatatcgaa tcgaaaaatt
     7081 tcaagaacag tctggtttca atctaaaaaa agccaacgat ttactgtttt gctatctttt
     7141 attgcttcat gaacataatt aaagatagat taaaggggtt gtgacaataa ttttgtcaca
     7201 accccttatt tcgaatgaat agtgttcaaa agctagtttc tcttacatca ttttttcaac
     7261 aaaatgcatt agccggtctt ttacatcttc ggttgaatct ttgattgaat caccataaac
     7321 agagattttc ttttttcctg atttgatttt tgctaacatt cccatcaaag aatccaagtc
     7381 actatctgaa agaccatcta cgatttctag taatttttca tttccatcaa atttgtcata
     7441 gacgaatttt tttactttcg tccgagtagt catatgatgg atcttttcca ttacttttcc
     7501 cgatacaacg actgctgtcg ctacactggc agcggctgct acgcttaatc cgattgttac
     7561 ttttgttgat gttttcataa gtatcagctc ctttttatct atctccatca tagcatagac
     7621 aaaaaaataa acgaactaat ccactcagtg aaatctcaat cctttaggga aaaagttctt
     7681 tactgttcct tttacttgtt tcccaaatcc gacaggtatc ttatctaata ctagcaaaac
     7741 ccatccttga ttcccatcac gttgaaatgt ttctcctgct gtgtaagatt gccattcctt
     7801 ttgagtgatc ggcaagcaag gtatattctc tatctttttt gtagcaagcg ctaatgcata
     7861 gctaggttca aatcgattct ttttgaaatc tcctaaatgc aaacctgtac gtacgacttt
     7921 taaaccatcg agagaagggg ctaactcagg aacttcccaa agatggtcgt tgaacactaa
     7981 aagtcttcca gtagcttcat aatgaaaatc atttgaaaac tccgtccaga gtttttcctg
     8041 ctcttttgtc atttgcactt tacttttttt tcgtgtcttc ttttctttat gcatctgatt
     8101 ttgtccatga aaagtcagct ttgcaacaaa atgtccttca ccctgatctt tatgaggcca
     8161 tatacgtatt gttttttcca aaccagctac gcttccccat tcagaacgtc ctgaactaac
     8221 ggattgagtc aaaggaatct cctcaatcgt tactggataa ttttctacaa gccagctaat
     8281 gatctcttca ttttcttctg gtgcaaacgt acaagtcgaa taaatcagtt gtcctttatt
     8341 ttttagcatt tttattgctg aagacaaaat ctcttgctga cgtttttgac agtatagcgg
     8401 agattcttct gtccactctt ttattgcatt tggatctttt cggaacattc cttctcctga
     8461 acaaggagca tcaaccacga tccgatcaaa aaagcccgaa aaatgaggga caagttctgc
     8521 gggtgcatga tttgtcacta ttgcgttcga aactccccat cgttctatat tttctgataa
     8581 aatcttcgca cgtttcggaa agatctcatt cgtcactaat aaccctttcc ccttcatttg
     8641 agcagctaat tgggttgatt taccaccggg agccgcacac aaatccaaaa ctttttcacc
     8701 gggttttgct gcagcagctg ttccaacgat cattgcactt ggttcttggc tatattcata
     8761 cccagcttga tggaggaaag actttccatt gacagtgcca agaaatccct cattgctgta
     8821 gggagcgggt tgtaattctt cgctatggta agtttggacc atgtccaatc ctgccggttt
     8881 tagtggattc caccgaaatc cttttttcac gcttccttgt tcaagcgcag aaaaaaaatc
     8941 ggatgcttct tcgcctaaaa gaagacgata ttttttgata aattgctgtg gtaacgttgt
     9001 cgcttcctcc ttcattccaa tgtttcgtta gacattttac aatctttttt acgaaaaata
     9061 aaggtggctg atctactttt tcatgttgct gcctaaggtg actgttcctt taagatattt
     9121 tccaagtatt catccgtcac ctcgttttta tcccaaacag cgttcatcat ttcaagaaaa
     9181 tcttgagaag aatcatctga gcgcaaactt cccaatgcat taagccatac caattcaagc
     9241 gacttttctt ctttgatctt cgtgtgacct ttgacatatg agaaaaatgg ccgcttaaat
     9301 agcgaatcca tgtctaaatc agattttgca atgatttcac gaatactttc atggatagaa
     9361 aaaaaatctt tcaataagta gacaatgctt aaaacatcat cggaactgca ttcagctaag
     9421 tagttttcaa aataaacagt gatttcttct aatatcttct cttttaaccc gctgattgat
     9481 ttgaaatgtg tataaatcgg gtatgtagaa caaccgcaga actctgctaa ctctcttgca
     9541 gtaattgact tcattccata ttcttccacg tataccatac ttttgaacag caaatattct
     9601 ttactataat ttgttactct ccccatcatt cttacctccg tctcttttca tctacccata
     9661 aataaataac ataaataatt ctaaaaatat tattgataat tatcaaaaca tatttagtta
     9721 tatccattaa aaatcaattt ttccgcctta aaaacaagaa tatcttgaca aaatacccta
     9781 ggaaataaac aatagaataa acaaggtaac aaaaaaatta aataacgtta tataaaaaag
     9841 aaggcgacac tctgtgagaa taacacagac tgaaatgact ttccactcac agtttttgtc
     9901 taactatata caaaaacaga ataaaaagga ggtatttatg ctaattgaag caagaaaaaa
     9961 agagttactt gttctacaaa tggtcattca aaaaaataat tgttctttac aagaattatc
    10021 caatgactta catattccaa aacggacaac caaagaactg atccgaaaaa taaatgtatc
    10081 actcaagcaa tttttattga ttgatgaatt tatttattct aatcataaag gagagatcca
    10141 aaccaaagaa accgatcaaa ctaaaaagtt agctgttttt tctaagttaa aattatgcta
    10201 cctaaaagaa tccaatcgtt ttaactattt gatgttacta atcaattatc cacaaactgc
    10261 tgtaccaaaa aaatatttac ttgaacaact ttatatatcg ccctcctatc tcgaaaaact
    10321 gacaaaacag ctcaatcatt ccttaaaaaa attccattta cggatcctat ctgtaaaaaa
    10381 ttgctgtact cttgaaggaa atgagttatc tatccgtctc tatctttact tttttctttc
    10441 agatacattt ggaggtaacg attggccatt ttcctcactt gaattaaatg cactaaaaat
    10501 gaacagtaca gatgagcaaa tagaaaaaat ttcaaaacaa gaaaaaaata tctacttgct
    10561 gttaacttta ttcatattac gaaacaaaca acaggcatat tttccaaaaa cttcttctga
    10621 aatcactgaa ttgatggact tattgcagca tacacatgat tattcagaat actttacttc
    10681 tttttcagtg agtcgccctt gtgaagagac agaaacagag agagcctact ttaattattt
    10741 tttctattgt ttttttccaa atcaaatctc ttttcgacaa aaacaggaga ttggtttttt
    10801 attttccaca agcaaaaacc ttatttgtcg acaagtcggt caattgatga cttacttaac
    10861 tcaacagttt cctctcaacc atttagaaaa taaaatacca atttattttt attttcttgt
    10921 gttggcagtt gtttttttcg aactgttggg tgaatccagc agtagttttt ctacactttg
    10981 ctttccagaa gccacgtcca atcattctag ttcttttata caggaaaaga aattaagaga
    11041 aaaaatcgat acaatttttt caaaaaatgg ggaaagaaac caaatcagtc aataccttag
    11101 tcaattgatc caacacttac tacaaacaga aacgaaagag cagttactca tccatttgca
    11161 gataaccaaa cagtttacag gaaattatca tcttcaaagc catttgcagc agttatttcg
    11221 caaagatgct gttaaaatta ccgcatattc agaacatgct gatttgatca ttacagatca
    11281 gcatgagaaa atttcagatg aaacggagac tttctatctg gatacaacgc acaatacagt
    11341 gttatttggc aagttaataa aagcggttca taaactgtat atgaaaaaag gttatgagaa
    11401 caaaacaaag aggatgtgac aaaattcttg tcacatcctc ttattccaaa taaatggtat
    11461 tcaatcagct aactctcggt attagctcag atcaaagcgc tgatttcaca acttctttat
    11521 tttaatctct tcggttgccg ccgaacaata agatcaagcg caacagctgc aggaatgtcg
    11581 aaagcgctgc tgcaacataa gtcagtgctg ctgcaaataa tacgtgtctt gccatcggta
    11641 cttcttcttc cgtcagtagt ccgccttcac tcaaaatttg gattgctcgc cgagacgcgt
    11701 taaattcgac tggtaatgtc accaattgga aaagtaatgc taaagaaaaa gcgaaaatcc
    11761 cgatattgat taacgtagag ttccagctaa gcaatacacc taccataatc aaggggaacg
    11821 aaatcatcga accaaagtta gctgctggaa caagtgctgc acgaatcttc aatgggacat
    11881 aacccgaagc atcttgtacc gcatgtccgc attcatgagc tgctacacct atcgcagcaa
    11941 ctgaagtaga ctgtgcagtt gcttgagaca aactcaacat cttattacct gaattgtagt
    12001 tatctgtgag atctccggca atttgttgaa caccgacatt atttatctgt tgactttgta
    12061 atatatattg tgctgcttgt gtaccagtca cattgttttt gcttctcact tgatcgtatt
    12121 ttcggaaagt actattgacg tacgctgacg caattccgga aataactaat ccaagaatga
    12181 ccaaaagaaa tgtcggatct aaaaaaccat acattccata accatacatt ttcgtttcac
    12241 tccttttcgt ttactttatt ttatcattag tagtaggaaa agaatgtgaa aagaccttga
    12301 atattcttta attctttttc acaaattccg atttcagttt catcggtcca aatccttcta
    12361 ccttgcaatc gatattatga tcgccttcta ctaaacggat gttcttgact tttgttcctt
    12421 gtttaatggc acctgacgca ccttttactt tcaagtcttt aatcactgtc acgctatcgc
    12481 cctctaacag acggtttcca tttgcatcta ataccactaa tccgtcttct atgacagttt
    12541 cttgttcttc tttgttccat tcgttcccgc attctgggca aatcaacaag cctcgatctt
    12601 catatgtgta ctctgagcca cattctgggc aatttggtaa tgtcatcttc tttctccttt
    12661 aaaatcttta gtgagcacta ttgtaacgga aaaagaagat cttgaaaaga tacatttgtg
    12721 atttttacta caaaaggcac gttttcgaac gaagtatcat tctgtttttc tgctcttata
    12781 cgattggcat atatcttgga tctctttata gatttcctct acttctgcta aatcttttgc
    12841 attcgcacca cttgctaatg gatggcctcc tccatgatgg cgtttagcca attcattgat
    12901 gatcggcccc ttagaacgta aacgtacgcg gtaataccct gaaggctgct gaacaaaaat
    12961 cccccaagcc agcacttcgt caatcactcc aggaagtgaa acgatcgaag ctgtctctga
    13021 atcatcgatt ccatatttat caagaatttc ttgcggaagg attattcttc ctgcaccatt
    13081 ttcatccacc tggatatttt gataaagata accggaaagt ttagcgactt tcatcggcat
    13141 ttgttcaatc tctctgttca aagcacttgc atcaaatgga taatttctca atatcgaagc
    13201 aatctctaat gtacgggacg tcgtggaggg atacaaaaag agccctgtat ctccgacgat
    13261 tcctgcataa agtaaccgtg cagccttaac gttcatcttt aaagattcag gaaacatcaa
    13321 agcaaattct gcaatcatct cactacagct acttgctttt gtatttaccc acacaagatc
    13381 tccataaggg tcatcattgg gatgatggtc gattttgatc agtttttctg ccaactgata
    13441 tctttgatca ctgattctgg gtgaattagc tgtatcagtc acgatgacta gcgctccttg
    13501 gtagaagaca tcttcaactt cttgcatttc tgctaaaaag cgaagccctt caatcgtttc
    13561 acctacttga cgtatttctt tttctgggaa actttcccgt aatagttcgg ctaatcctac
    13621 ttgtgatcct aatgcatcag gatcagggcg caaatgcctg tggataatga ttttatcgta
    13681 tttttttatt gtatctacta tttcttgctg tactgtcatt tcactcctgc tttctaagaa
    13741 cgttccatta cttgacaaac aacgattgct ttggaaacga tggtgttttc aataaacact
    13801 tcgatatcca gtttagcgga acgtctgccg atttccaata cacgtggacg aatgtctaat
    13861 tcgctttcca attggatcag ccgcaaataa tgtaggttca cttgttcaat caagatattt
    13921 cgtttttggt tcatcaccat tgttttttgt gcgacatcag aaatgatttc gctaagtacg
    13981 ccaaaagaaa tggttccaac gccattgacc atttgtggtg ctactacgaa tttgaactta
    14041 gggttttcca aacgatttcc ttcacggtca gtatcaatcg tatggatatt tccagatatc
    14101 tgatccgaaa tcgtatctgc aatctgcggt tgtcgctgga caagctgcat cgctttcatt
    14161 acatcttgcc gggtaatcaa gccttccaat gtcaagtcat cggaaacgac cggcatgact
    14221 tctagcccat cccagatcat ttgatggcta acagaggcaa tactcattgt tttctttaca
    14281 ctgattggtt ctttcgtcat cacccgatcg atgatctggt ttggcgattt ccctaaaaca
    14341 tcttttgccg taacaatccc catcaaacga tgatggcggt tgacgactgg aaaacgcgaa
    14401 tgctgcgttt cttctgacaa acgctgataa tcagaaatcg tatctgtctg ctgcaaataa
    14461 tgagtctttt cagctggcat atagatatca ctgacaagca tgatatcttt tttgatcaat
    14521 tggtcgctta acgctcggtt gatcatggtt gcgactgtaa atgtatcata agaggtgcgt
    14581 aagatcggca tttcaagatc atcagctagc tttgcaatct cagcagtcgt attgaatcct
    14641 cctgtgatca atactgcggc gccatcttcc aatgctaatt tttggacttc cgcccggttg
    14701 ccgacgatca ttagtgatcc tggcgtaata tagcgttcca tggcatgttt agtcatcgcg
    14761 ccgatgacga atttattcaa gaccttgtct aatcctgccg ccccgcctaa aacgtcccct
    14821 tcaatgatcc tgacgacctc gccaaatgtc aaacgttcaa tatgtttttt taatttgcgt
    14881 tcgatacgga tggtccctac tcgttgaatt gttgaaacta gtccgacatt ttctgcatct
    14941 ttgattgcac ggtacgctgt tccttcactg acattcaatt cttttgcgat gcttcttaca
    15001 gaaattcgat tgccaacagg taaactttca atatattcta aaatcaaatc atgttttgtc
    15061 gccattttct gcctacactt ccagcgtttc cgagacgctc attatttttc cttcactatc
    15121 ttccagtaac tctacaaaag attcgggatc ttgttcaatg acagggaaag tattgtaatg
    15181 gattggaact actttcttgg cacgaattgt ttgcgcagcc tttgctgcat cttctggccc
    15241 catcgtatag ttatcgccaa tcggcaagaa agcgacatca atatcgaatt cttctgcaag
    15301 caatcctaga tcactgaaat aagcagtatc ccctgcatga taaatcgttt ttccttctgc
    15361 ttgaataata attccgctag gctcgcccat atactgaacg ataccgtcta cttcatagct
    15421 tgaactatgc tgtgcatgta cgaattttac cacgccgaat ggaaacgcat gttttccacc
    15481 gatattcata ccgaatgaat ctactcctct gctgttcgca taatcagcaa tctcaacaat
    15541 actgataatt gtggcttgat tttcttttgc aataggaatc atatctccta tgtggtcact
    15601 atgaccatga gtaatcagca accaatctgt ctttacttct tctgcagtta agtctgtcaa
    15661 tggatttcct gtaataaacg ggtcaatcat cacgcgttgg ccattttcca tttcaattgt
    15721 taaacaggaa tgtccatgat acgtaatttt catattttac acctcgcgtt ttctctgtat
    15781 cttttttatt aaaaacgatt tcatcacttg cacatcaatg aaaaaatata gctgctaaat
    15841 atattttcat tggattgata gtacagtatg tacaaagcaa ttgtaacaga taatacagga
    15901 tgcaccaagt accaagcaga tataatctca agtttgaggt ctctgctctg cttagcttct
    15961 cttctcgtcc cttaactaat taaatcagcg taaataggat ggacgatctt ttctaaatcg
    16021 gctactttta tccgaaggct tctcccgatt tcaccgcttg acacaattac ttcttctttt
    16081 tcttttaaag aactgtctgc taaaaaacaa taatcaggat gtgcgagttt tattccaata
    16141 ggggtgtttg ctccgtgggg atatcctgta tgcattaata caaaatccat tccaggaaaa
    16201 ccaactttac gatctttcgt cacttgtctc gtttttttgt aatctaagtg atcgttcaaa
    16261 ggaatcaatg cgatgatcac cccagttttg tttcctttca ctacgagagt tttacatatc
    16321 aaagctggat caatccctct tttttgtagt tcttctgtga aagattcttc taccacatga
    16381 ctaaaatcaa gtggttgata gctgatcttt tgttcttcta aataacgttc gacttttgtt
    16441 tgactcatca ttgattcact ccctttattc tatcgtttat tataaagcga gggatgctgt
    16501 attcaaaaat tatttgtttt tcgcaaaaaa agagcaagac gagcactcta tagagaggtt
    16561 catcttactc tttttgttta ttttttattt cgacgttgag tagcttccat aatgactggc
    16621 aagatcactg ggcggcgttt tgtttgttca aataagtaac ggcctaattg atctcggatg
    16681 tcttgcttta atttgctcca ctcaaaatca ttgctttcta aatgtttctc aacgattgtt
    16741 tcaatcatat tgctgctttc tttcatcaga tcacggctag cttttacgta aacgaatccc
    16801 cgtgaagtaa tttgaggttt tgaaatgatt ttcttttctc gccgactgat agtgacaacc
    16861 gctacgaaaa tcccgtcttc tgacaagatt tttcgatcac gtaaaacaat gtttccgata
    16921 tcacctatgc ctaatccatc aatcattaca ttttctgcac ttgtagttcc tgcaacactc
    16981 atacgcttgt tcttatattc cagcacgtct ccgcgtccag taatatagat atttttgtat
    17041 ggcatcccta ctgcatgagc caaatctgca tgagcagcta attcacgata ctctccttga
    17101 actggcacaa aatatgttgg tttcatcaaa ttgatcatta attgcaagtc attaggattg
    17161 gcatggccag aaacgcgcat attctcagag atcaacttca ctgttccacc agctcgataa
    17221 atgatatctt ccgttttcgc cacgatggtt tccatcgcga tgcttggcgt agtagtgata
    17281 taaaccaaat ctccttcttc aatcttgaca ttacggtgtg taccgtttgc cattttttgc
    17341 agagacttga tgggttcacc cattcggcca gtttctaaaa tgatcagttc ttctggatca
    17401 tagtttttca tgtctttcaa cgtaacaagc agatcttcac ttggtaattg aagtttttct
    17461 aaacgcatcg ctgtgcgaat aattcgttcg aaatcttgac cagtcaagac aacttttcgt
    17521 tgtgcttttt ctgctgcatc caatacttgt tgcactcgtt gcaaattact tgctacacaa
    17581 gcgacgatga tacgcccttc ccaatatttg atcgtatcaa atacttcatc tgctatttgg
    17641 gcttcagaag ctacaggctg aggattttct gcatttgccg attcacttag taaggctaag
    17701 actccttctt tgccgatttc cgccaatcgt gcataatctg tttgatacat tgggatagcc
    17761 gtttggtcaa atttaaaatc tcccgtataa acgatactac cttcttttgt tttcagattg
    17821 atccccactg aatctggtat cgtatgagtg gtacggaaaa agctcactac tgtttcacca
    17881 aagtctattt ctgtatgctc atctaccaca tggaaatcct taaatccttt ggctgcttca
    17941 ttacgactga cattcaattt tgctaactcg atcgtcaact ctgtcccgaa tactggtaca
    18001 gaaatttttg acaacaagta aggaagtgcc ccgatcgcat ctgcatgtcc atgtgttaaa
    18061 aagacaccag ctacacgatc aatgttttct tctaaatacg taaaatcagg gattacgacg
    18121 tcgatcccca acaactcatt ttcaggatat tttagcccac aatctaaaat aaaaatatcc
    18181 tcgcccactt ctgcgacata catgtttttt ccattttcac gaacgccgcc taatgggata
    18241 attttaatgg tactcacaaa cttcacctct tcttatgaca tccaagttta aagatgtcga
    18301 ttttcttctt tatctaaata tatgagccat tccaatgaag catatgcaaa atcactattt
    18361 ctcaacttat ggagaatcag caggaaaatt accagcacat ccgcgttctg acagttggat
    18421 gggcatttta ttttggatat acttcattaa caaaatggat cttttgcgaa acgctatagc
    18481 cagaatactt atataagtat tcagctgttc cccattatta tacaacaaat aaactaaatc
    18541 gctagtatca gcaattgtta gaacaactat gcacgtaaaa atccctctgt agcatctagg
    18601 atttcttttg ctattcctct ttcatttctt cttcgtcggt ttgaaacata cttttttcat
    18661 tttaccacat tttttgcaat aactatagtg actttttata tatacagaac ctcatgttga
    18721 tggtgtgcaa acagcataag atttaagcta gctttaagat aggttgtcta ttatcaaatg
    18781 catctactag gagggatgca aaatatgaat tttatgaaac gtgcatggaa aagtacaaaa
    18841 gtaaaatggg gacgttcatt gttattgttt gccgtgttca cagccattct tatttttgtg
    18901 ctagctggcc tcacgattcg aagcgctgca gaagaagcag cgaatcaagc acaaaaagaa
    18961 gttggagcaa cagtgacttt aagtgccaat cgagaagctt catttaaaaa acaggaacaa
    19021 acttcttcaa gcggttctac cactgaagaa cgtccagatc caggcagttt ttctcttaca
    19081 ccagtttcct taacggacgc ggaaaaaata gctgaattag ataatgtaaa gagttattcc
    19141 tttgaaagtt ccgcctcagc tatggcaaaa gatggaataa ctgccatcac tagttctgat
    19201 tcaagtgaag acagttcaga aactactgat gcaggcggtg aacctgctgg aggaatgggc
    19261 gggaatccgc aaatgactca agcagacttt caaatcagtg gtgtgtcagc aactgcacaa
    19321 aatagtaatt tttctgatgg aacagcaaaa atcacggatg gtgaaggaat agatgacagc
    19381 gacaaaggca caaacaatgt agtcattgat tctactctag cagaaacaaa tgacctggca
    19441 gtcggagata ctttcacaat cacgagtact gaagatgaag ataccactta tgaaatgacg
    19501 atcaaaggaa tttatgaatc cagcgaaaca agcggcagta tgggtatgaa attcaacttc
    19561 atgaatccgt cgaatacact ttacacttct tacacttttg caaatgaact aaatgggaca
    19621 tctgacgata acacgataga ttctgctatt tacactctat ctgatccaga taaaatggat
    19681 gagtttctca aagaagctga gaagctgatc gacacagata catttagctt acaatcaaat
    19741 gattccatgt atcagtcaat gttggaacct ttaaacaacg tggcaagttt ttctaaaaat
    19801 gttgttttac tagtggctgt agccggtatt atcatactta ctctgatcat tatgattacc
    19861 attcgggagc gtcggcatga gttaggcgtc ttgctatctt taggagaatc cagaagtaaa
    19921 atcattctcc aattgtttac cgaagtggct atttgtatga ttcttgcatt aggagttgct
    19981 tcgcttagcg gaaacgtcgt cgcgaatgcc gtgggacagc agctacttga ccaacagaca
    20041 gaaaccacga cacaaaacca gcaagctcct ggcggtggac aaatgccagg taacagacaa
    20101 gaacaaggcg gtcaacgcga tggtcaacaa ggaaccacga ataatccatt tgctgtttct
    20161 gatcaagtca gcgaattgga aatcaatgtc aaacctgcac aattgggact attagccgga
    20221 gtagcatttg gaatcagtct gttttctgtc tttttagctt ctatagggat attaagatta
    20281 aacccaagaa aaatcctatt aaactaaagg aggaatttga tgttacggac agaacaattg
    20341 ggattttggt atcaagatcc gcaagatgcg ctttataaag atgtagaact gaatttcgaa
    20401 gctggaaaaa tgtacgctat tttaggagca agtggttctg gaaaaacgac ttttctttcg
    20461 cttatttctg gactagatgc accaaaagaa ggaaaggtat actatcaaga tcgttcactg
    20521 aacaaaatcg ggttaagaag ttatcgtaaa aatgatgtct cgattatttt ccaagcttac
    20581 aacttgcttc cttatttatc ggctctagac aacgtcatag cagcaatgga aatcactaag
    20641 accaagcaag agaattatcg acaagttgct ttagatcgac tggctcgtgt aggaattgat
    20701 gaaatattag caaaaaaaca ggtgaccaaa ctttcgggag gtcagcagca gcgagtcgct
    20761 atcgttcgtg ctatctgctg tgaacatcaa ctaatcgtag cggatgagcc tactggaaat
    20821 ctagatgaaa caacttcaca agatatcgtc aaacttttcc aagaaatcgc ccatgaacaa
    20881 aatcgctgta ttatcatcgt gactcatgag attgaagtag caaaaagctg tgatgaagtc
    20941 tttgaactaa aaaataaaaa atttcaaaaa atcgaagttt aaaaaacagg ataatgatca
    21001 aataaaaaat ccgaaccata tctgtctcgc agatatggtt cggatttttt atttgcttga
    21061 ttcaattagt aataagtggt ttttattttt tttcgtcttt tcgagaaaac ttgtctttga
    21121 cttcgtcgcc taaatttcga gctttttctt tgatgtcagc acctagtgat tgtgctttcc
    21181 cttctgtttc tttgctcttg tcgtctgttg ctttgccgta tgcttctttt ccttcaccga
    21241 ctactttatc tttcatatct ttagaacgtc cttttaaatc tgccattgtg cttcctcctc
    21301 ttagtttgtt tattgatcta ccttcagggt aacatcaaca acagatacag acaaacagaa
    21361 cgctcgtttt ctaaaaaaga tagttagagc tgt
//
LOCUS       DACDLM010000049        21152 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.049, whole genome shotgun sequence.
ACCESSION   DACDLM010000049 DACDLM010000000
VERSION     DACDLM010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21152
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.049"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..168
                     /locus_tag="IV356_001868"
     CDS             <1..168
                     /locus_tag="IV356_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAP9015555.1"
                     /translation="LFSLSHLNLYFIPYFMTSLILSFVYDNSDKRLIVPVTIHCFYNL
                     IVILLSVVFYT"
     gene            313..636
                     /locus_tag="IV356_001869"
     CDS             313..636
                     /locus_tag="IV356_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015556.1"
                     /translation="MARSRIAKIEQTKKDKKISKNKTKFFKAEDVKRIAWSVKTFDED
                     RYVKVSMNGLFVQLGNFSNFKTIDELYPEIRNIVDSKGLIVAKRKSRNSGLAYCKNKG
                     IMIPA"
     gene            1054..4683
                     /locus_tag="IV356_001870"
     CDS             1054..4683
                     /locus_tag="IV356_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015557.1"
                     /translation="MKKLKLISIALFSLITMSTARQSIVSAEGTSTKAVVEESGDKKV
                     AIDDKVKNEAEKATVVQGADGLMYVVVDENDPEKLLEAESPLKNQQENTGAVEVGVDE
                     KRQEKADKANEKVKNFDDIDYNDISSLQSALNDPKFPFLSEDELNEKLQKTKNTFESE
                     ALMKKTRGYFSQRILELSNNLNDVPKRAKVSRHALVSNRASQVSETRINPPNGYPWVI
                     YLIRSNGYSYTENYAIRRTIDGKEAFCLQAGVQATNTYTGSTSGYLSNSQREMISSIL
                     SAYKELGGWANNDAGKQRWIATQMLVWENSNEKPKSITVTPNWKNGATKWKNDLVARA
                     NAIRVRTKWDSTSKTVDEGDKATFKVTNTYGDHNLHVKSVSGGGKATISNGTLTVDTT
                     GATGNKITVDMIKGSHPSDAHPTTVWSNGSYQKLVTGSFYISTSVTVNVKRKGTVEVL
                     KVDSETKKPLSGATFRFSYSGKTKDVTTDSNGKAKLTERLKAGTVVKVKEIKAPNGYQ
                     LDSSEFSITVKENQNVTTTRTNKKSTGSVEIEKIGDLDGLGLPNVVFTIYNSDNKVVK
                     DNLKTDSNGKIKVDELQFGKYYAVEKQGVTGYDPDGKKYNFEISQDTPFTKPAKVKVT
                     NIYEVSISEKVSDMNESQVLKNNWSADPNDYLQYDITTGNLKKSGERNVQSFIIEGFY
                     DNKNVDVSKSEVYVGSTNVTNSFDINNDTNNGKVIAKAKTSVLTNNDFYNKSYNLRIT
                     MKIKKSTLENTEKQKNLTIVKNSKVTVGSKISKSASSNDVETVLYSRKVTINHIDEKD
                     KHLLKQDIDYKYDGETYEYKPRTDLFDKDGNNYKSDVIHKGKIDGKDIVLNTPYHIPV
                     LSVNVDRIQIDTARAVKNGYLPTKIELSKKEEYEKELEKIVFKVKITDIDNNKVVYDE
                     NFKYKEFNSHMSLDLPTEYLTKNKKINYSVDILLVDNPDKNKFETETKDLRTIGYTSS
                     EKVLTNKDMTNNQVNYSAVVRTVKERENNNPVKEFNESINYKFTDSTKTKTGYGISVD
                     LEPTYRNEIGKQIDMKVYSYPMNELIDSKIDEIYQSGGKETEVKMDRLKNDGKVESGI
                     STQNLSFQFPHMNIERKTGNIYADSQRNDESIKYELIDGGRKLYVPIWCDLGNYSIAI
                     KSSNFGGNYISLDMNQNIDVYAYMYATIDSETKKDDELLLEPVYPESTLPDGWSKNEI
                     DWLNK"
     gene            4743..5105
                     /locus_tag="IV356_001871"
     CDS             4743..5105
                     /locus_tag="IV356_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015558.1"
                     /translation="MRVQSYGNSVFDVKREFQDSRRKTKKLIAYFILSAIVFYIVKFV
                     LELNSIVFTDMVHKMLNGEPINFNFDYMLEKAQSNQIVAFIVSIYYFIEKSIFSLKDF
                     FFEMLTKLTTFYNKISKN"
     gene            5339..5761
                     /locus_tag="IV356_001872"
     CDS             5339..5761
                     /locus_tag="IV356_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015559.1"
                     /translation="MIYVAFFLDGSDVMLRDMPKMILLMFVGFFLILVIAYYSLNGYT
                     QDSSVKGMQETLRTTAIANRDDSIRVEKGRFALIKSDFEKDFKEKFGKSKNLNNETAD
                     YKFDYLTDGKDGIKAIKVKVESGSKEYQATCILNVAND"
     gene            5773..7188
                     /gene="cpaF"
                     /locus_tag="IV356_001873"
     CDS             5773..7188
                     /gene="cpaF"
                     /locus_tag="IV356_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component"
                     /protein_id="HAP9015560.1"
                     /translation="MRVVEEKKISPKIEETPKSKINIASIIKKNGIKENSEAIEGNLD
                     FLTKLLEEDSGNYEPPIEDAKLNMIRDDLTRNYSQEVLQALTDDEIRRKLVQVVLKEH
                     GTFFKKDKEVAEYVVRECIGTGIIERIMTNDEITDVGWNGSQLSIETNSNKWLFDGDK
                     LNITQEYIERVISKYAVVNDRAFNSGNPIMDGMFKNVRISATHIDNSPDGSTFSMRVA
                     RPRLALNKENFEDFAPDYILELFEKMMKTKANICISGETGTGKTELQKLLLSFIDNHD
                     RMIMIEDVQETHAKELFPDKDIFSWITTPKKAISDLVKASLRNNPRWIIVSETRGSEA
                     YEMLQAVLSGHYVVTTLHAVNARAIPRRFVNMCASGFKINENAVEEDINRYFDFGVHI
                     KKTVVDGKVIRYLNEIVEFSASEPTTVFKQKFINGKFVIENGSLSEDFKEKMAEKFIT
                     FEFPEDQTNTEESLPEEEEVI"
     gene            7205..8020
                     /locus_tag="IV356_001874"
     CDS             7205..8020
                     /locus_tag="IV356_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015561.1"
                     /translation="MTKRKGLMDVSELNAYQVAYGKPLDYRDYLNYVGLPCLFMGGFS
                     FALCYYWWIALICGVIGGVYGFKVIMPKSIKRSYELKSLQERNKFINNMTQILTDDSK
                     TVTRALSIAKQRTKGELREDIQILESRLQGADKFQIAEAFREINNKYYSDVVFTQYFE
                     QLETAIYEGRNNSDTMKQIKSYHNDVKRKTEGFMKIKDGYLQDMKQMMFIVAVFIGAI
                     TFAFGFSTFYEGFARSPIGWVFGSIYFLIMVSFMKSFFKHYFDDEIMSLGVSN"
     gene            8020..8817
                     /locus_tag="IV356_001875"
     CDS             8020..8817
                     /locus_tag="IV356_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015562.1"
                     /translation="MKVKALKKKRKSSISPLKITKTEHKSFWIKLLGDVYYQKLREMN
                     NSNIAIIKWQKQRLKKSLIFILVGFLMYLFLGKEWYYLAGGIATSVGFYVWQAKSING
                     IYNQFRFERHLQFSKFTRLLIPYLKQKKDGGNLYGVFAKIVKRLDYDTDKKLLMKLMQ
                     EMTDQPNDIRPFTEYAEQTSGTDMSVLFMSTVYDIRQGSADLDVIEELDRLASEELMA
                     GIDSIIDYKSRRFVFFPTKIAMTSFILVVGFAVGVLFMNLKDINFGQ"
     gene            8835..9197
                     /locus_tag="IV356_001876"
     CDS             8835..9197
                     /locus_tag="IV356_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4320 family protein"
                     /protein_id="HAP9015563.1"
                     /translation="MQEQSVMEIIKWFIGLMMIMAMVSIGLFCVQLQDINTFKQQVNY
                     QIERKGGLTTEAVEAIDKYSATNYDRRFTIESDKLNQKVSYGEEIDYTIKATIPIQIL
                     PLPDVTLSFNGNSVSQIR"
     gene            9369..9590
                     /locus_tag="IV356_001877"
     CDS             9369..9590
                     /locus_tag="IV356_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015564.1"
                     /translation="MEAIQENRKDNQETSEKNKKKRKKKVDKFTEMTDKIIEKKGLKP
                     KDFDRQAIKEARQKLYDDFVKENISQLLD"
     gene            9609..9884
                     /locus_tag="IV356_001878"
     CDS             9609..9884
                     /locus_tag="IV356_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="HAP9015565.1"
                     /translation="MKNLVISKFAMLPRMDFFDNVSKFMSNMTSKLQGISLSVIIFCI
                     VVTGLMFLFGEGPSRTAKKWLTYIVIGAIIIFGASTIGQTIKSVGGF"
     gene            9993..11819
                     /locus_tag="IV356_001879"
     CDS             9993..11819
                     /locus_tag="IV356_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015566.1"
                     /translation="MNQRFEYNFEDVEPKLLKKGKGLKKKNKYTLKQAEALVGWIQHN
                     WSDKTTITLICSDTEEGTKYAFDGIEITPFSIGGQEKLLFPDIEGQILQAPDSMISDP
                     NKLILDINDQYKHEPDVAEPTKESKSKLNLKLPSVVLPFAKKKNKLMNELIEPEETDI
                     YEEELEEQEEIEELVVSSEETEEVEEIETVSENEEETEEIFDFEDEEEVENVQKGDLS
                     TSSQNGLEAVNDPQVPPYISSQTPNYSPQYQAPNVLQPLRKHETVQLVTLKEYCDLGE
                     EIETSISQMVEKLKPESLFKFIGIPSTGLTNTRIDEYRSNHAMLRLAEVKFENLREHY
                     SRQIISFKAEALDRLRTAVDIAWKKPYDLDVKKNKAEELSKMEAEAEAKLNEFVKRQE
                     NNVNDKIKKFEIEQEIDLKNFIARQEADKAVFIATEKDRTQNLIDSKAESINADLLET
                     KDKFIDEEMYKMKIEMNKNLFDGKQKIKSELATELAKANDNVWENALKFIQEIQDEIE
                     AKTPIWAAEIKEFNSLEEQEHERMKQTKELQLKEESIEIKRLEAEMNLKRMEELDHEN
                     KMLKIKLETALSKNELLAMEQDTKQVVNGSNRVGALNLFSKR"
     gene            11832..12548
                     /locus_tag="IV356_001880"
     CDS             11832..12548
                     /locus_tag="IV356_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015567.1"
                     /translation="MSVFNNKVMLGNCYVNHIGFYDGGTYRVLFLRLSVFSYSKDGKG
                     HYENINAQISCPLDRNGETTTTSSHPKALMNKFIFEKLDRNLVEGMKISIHGNIRGTE
                     QVLLNSGWKNFGQLSPLEKEEYQKIPKNELVTRNQTYIYIEEVSMPEKEEFRKSQSKV
                     TKEDVEVAEPNQADEILSDDTDPVNDEGEVIEVFEAEIIEEEEEIKSFDKRMYREKPK
                     GYVNFEDMYYDEYSNEPPIN"
     gene            12561..15419
                     /locus_tag="IV356_001881"
     CDS             12561..15419
                     /locus_tag="IV356_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HAP9015568.1"
                     /translation="MKLVQNNEVKEIKNGFVKNSNKILGKLKKVGSFKKNKYHTGKIE
                     GEDLPKSLQDKLNVPLVFIGVFLGSIVFLAITYLLNFLKALLVAIGQSESGLLGVEFD
                     PKFSLAYLKPLGDTKQYFMCAVVAVIGVAYLIYGKLNHESEKNLVYGQKGDSRLSTIK
                     EIKRDYHEIPEKTEVYDGIGGVPISHYQDKYYIDRDTVNTVVLGASRSGKGETFVVPL
                     LDNLSRAKIQSNMVVNDPKGELFSASKETLEKRGYRVLVLNIDDPLESMSFNPLQLVI
                     DSWANKDYHEASKRANTLTSMLFASGMSTDNEFFYKSAKSAVNAIILTIVEHCFNNDC
                     IEKITMYNVAQMLNELGSLFYTDPKTGKEKNALDEYFNTLPQGNQAKIQYGSTSFAGD
                     KAKGSILSTASQGIEMFTSDLFGKLTSKMSIDLKEIGFPKSIRFKVNTNLVGKRISIS
                     FLRKENDVIRLIKKYRVKVKALGLCVLNFNEYLQDGDMLDIRYEEEKSRAWYRIEFPK
                     KQANSHDTSLVTKKFKSGKNYSDLEISTLRLKYTDQPTAVFMVIPDYDPSNHVLASIF
                     ISQLYTELASNCKQTPDKKCFRRVHFLLDEFGNMPAIDNMDGIMTVCLGRNMLFDLVI
                     QSYSQLETRYDKAFKTIKENCQNHILIMSNDEETIEEISKKCGHKTTINRSASSKHLD
                     TDSSVTSSAEQERVITVERASQLIEGEQIILRNLHRQDTKRNKIRPFPIFNTKETNMP
                     YRYQFLAEDFDTQRDINEIDIACEHINLSLQDNQIPYARFIKDLKTRLEYSIINNIPI
                     SEEDYQDYLNLSGSQQTINEEELLKLVNTEVKSQDMEGQVLSEQEMKINIYLKESQKE
                     AIELVKVINGRLADENSADMVIKTINSQILDTPFIQSLINDSIAIHNVQESKDQIMIL
                     EQQLANAYELAVFKTKNSILKNKIIKLKNAMTKLAKAI"
     gene            15470..18106
                     /locus_tag="IV356_001882"
     CDS             15470..18106
                     /locus_tag="IV356_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015569.1"
                     /translation="MQWLKYKWPIIVSLIIILFMAYPQRVFALPWITDNKEVLKFLTK
                     YQDYLQFTKGGFGSIVVQSLSWGLIRGAYFVCKSAENLVPQSLSLFSFVESSSLGAVY
                     QSVLNTVVVGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALILLMPTMISSGIQ
                     FAKTFYKDSTTITKADGGVAWSLIEDGVTDLVYINKNDAYDRLGKDGVQKNALKEKNF
                     FSYDFSEVITVDTAKDLEDDNKKAEYLQSRLTPDGEGNMQAVKIDDGWMSMFSDSFKG
                     GYYRFTKNTFALTLGLLSLAVAYVFSIFIIVTAILELAFKRVLGVLVFATDIETGQRS
                     KVVLSDILQCYLTVGFQGFGLSMFAMFVSYLGTGGGSSVNPFIKAVAYVCAVFVLIKG
                     SGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGNGNGSDSGEGED
                     RKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATIASERATKPFKSMRDIAND
                     TKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSMPTRLSDRKDGAKVENADR
                     IMSSSERMREAMKNNAESNNNPVSAIQQKVQQDIEERKNAMHGQAKSAEELINQKRQE
                     AKYTPEAMNREEMLRKRVEGRTGANMDEKEALTKERIQEAKNSNTGLEKLVKENLQNS
                     TSSQGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNGQGTKTIDVRENLQSSSTSQ
                     PKTVDVRENVQNSTSSQDFKSVDVRENVQSSSASQPKTVDVRENVQSSTSSQGFKTVD
                     VREDVQKDSGEMKEKTQKINIVEDRKSAKRFDSNHETVIIDSEIRENDKGSKPRRRFT
                     YEDNELFRDTLNDPNPLFDNLN"
     gene            18130..18465
                     /locus_tag="IV356_001883"
     CDS             18130..18465
                     /locus_tag="IV356_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015570.1"
                     /translation="MPAFYEVKMMYRNPKNIKQEIKLFFFYLVDLGIVAGSVMASVYF
                     AKLIPISPMMKFALYLLAFVVGVWMCVRTPNHPKERNILMLYYLFKMDRNRYHEVEFK
                     RNSRGKIEL"
     gene            18462..19079
                     /locus_tag="IV356_001884"
     CDS             18462..19079
                     /locus_tag="IV356_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015571.1"
                     /translation="MIVAESNENKLSGVLDKFLELVIPKDKDMCELLPYKKILKDGTL
                     VTNDNKYQAFFKVKTTDLTSISEDGFMRMVNKLTYLNRVYLEPYKIYSLTYPTETVNQ
                     AIYWKHRIQEAKRSLLSNNDPNLETYLKWNLKLAYDNYERVDLVSTLPELMFVICVYG
                     KTQKEVKNHADVMKQAGGRELDLQRITEGDLINVITKLMNPNTSL"
     gene            19096..19563
                     /locus_tag="IV356_001885"
     CDS             19096..19563
                     /locus_tag="IV356_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015572.1"
                     /translation="MLKHCRKGFCKVIKGKNAADLIFEWKESNLINVRGKNGSGKTER
                     VMASIDNSRPRSRALVITDEKNHYKGIRTIEKKYLTNNDLKVVDDILNIYPDFNLVVF
                     DETIPVTEIKGFYQSFSNLANKYEEVLFVWITEENSNSKSAFFSEKNAFLHSI"
     gene            19579..>21152
                     /locus_tag="IV356_001886"
     CDS             19579..>21152
                     /locus_tag="IV356_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tra protein"
                     /protein_id="HAP9015573.1"
                     /translation="MIVSKKLARNLVSEGYDLRLVEKYQPSGGIKFDERYISTGDGYV
                     TSIAVIEFAEDVNSRWLTDIMAIPNTIATFDVCTADKEDLLHKINTSIGELDYRSTNE
                     NRTTDKTDALLDKYNLEDFAQEITKRGEVVKTVHARIFVYSDSLEELEKRISEIRKDL
                     ASVNHKAIVPQFRMKDEWMSLFQDGMEQESKLFAKKGLTVPAKNIGGGIPFHHKSLKD
                     PRGFYLGTTSTGGAFIFDPFYSTKQRRSFNGFILGKMGFGKSTLIKQLQEGLQAKNCF
                     IRGFDKSGEFEGMVKKAGGVYVDLGGGDMVVNPLQIYATVMKKDQFGNDVVDESKSFQ
                     NHITKCSNQIRFLEPEIDTATVREYTLMLQDFYIHYGILPKEWREARDDNERNQLNTN
                     ICNLPNDSYPIYGEFLKFIENQQFKIKNATPERVRSIELIKLIVTDMCTTYPQIFNGV
                     TTMPNFDTTKIVYYNIDSISKMSAPVFHCQLFTALTTIWNSALQNGKIQKENFKKYGS
                     DYYKYAQDFMVLIDEC"
BASE COUNT         7995 a         2712 c         4138 g         6307 t
ORIGIN      
        1 ttgtttagtc tatcccactt aaatttatat tttattcctt attttatgac gagtttaatt
       61 ttgtcttttg tctatgataa ttcagataaa aggctgattg ttccggttac tattcattgt
      121 ttttacaatt taattgtaat actgttaagt gtagtttttt atacttgaaa aaaatagacg
      181 aaaacctaaa aatacaaggt ttttatctat tttttttatt ttgtttttat ctatcaggtt
      241 gatagaaatt gtcataaatg atataattaa gtatgaactg atttagtaaa aaaattaaag
      301 gagtgatagc tgttggcaag atcaagaatt gctaaaattg aacagactaa aaaggataaa
      361 aaaatttcta aaaataaaac aaaattcttt aaagctgaag atgttaagag gatagcatgg
      421 tctgtgaaaa catttgatga agatcgttat gttaaagttt caatgaatgg tctatttgta
      481 cagcttggta acttcagtaa ttttaaaacg attgatgaac tttatccgga aataagaaat
      541 attgtggata gtaaaggttt aatcgtggct aaacggaaat caagaaactc tggtcttgct
      601 tactgtaaaa ataaagggat catgattccg gcttaaatca gtgaaattgt tctttgaaaa
      661 cttaatacta ctcgtactgt agcaatgttg ctatgttaca gataaaagcg taaggctaat
      721 aagcaaaata gcaaccaagc atactgttat ttcctttgcc aagaggtatg taaatacgtt
      781 agcaatagaa gtgataaggt tagtatttca cgccaaaaaa tacaaaagtc gatccattga
      841 aactactaat tatgaggtgg cgtaaatggt aattattcag aatttctatc taggaagaac
      901 ctatgaaaac cgtcctagag atcagaatat tgacactaaa aaattcagca cagtaataaa
      961 tgtgctagat acagggtaac tctttactac aagaaatgta gtaaagagtt gttatgattc
     1021 tttattacat ttctttctaa aggaagtgtg ataatgaaaa aactaaaact gattagcatt
     1081 gctctattca gcctaatcac tatgtcaacg gctcgccaat caattgtttc ggctgaagga
     1141 acgtctacga aagcagtagt agaagagtct ggcgataaaa aagttgctat agacgacaaa
     1201 gtgaaaaacg aagcggaaaa agcgactgtg gttcaagggg cagacggctt gatgtatgtg
     1261 gtcgttgatg aaaatgatcc tgaaaaattg ctagaagctg aatctccttt gaaaaatcaa
     1321 caagaaaata ccggcgctgt tgaagtcggt gttgatgaaa agagacaaga aaaggctgat
     1381 aaagctaacg aaaaagtgaa aaactttgac gatattgatt acaacgatat tagttcgttg
     1441 cagtcagcgt tgaatgatcc gaaattccct tttttatcgg aagatgaatt aaatgaaaaa
     1501 ttgcaaaaga caaagaatac atttgagtct gaagcgctaa tgaaaaagac aaggggatat
     1561 ttcagtcaaa ggattttaga gttaagcaat aatttaaatg acgtaccgaa aagagcgaaa
     1621 gtgagtcggc atgctttagt tagtaaccgt gcttcacaag taagtgaaac acgaataaac
     1681 cctccaaatg gttatccgtg ggtgatttat ttaattagga gcaatggtta tagttataca
     1741 gaaaattatg ctattagaag aactattgat gggaaagaag ctttttgttt acaggccggt
     1801 gtacaagcga cgaatacata cactggttca acaagtggtt atctttctaa ttcgcaaaga
     1861 gaaatgatta gttcgatttt atcagcatat aaagaattag gcggttgggc taataatgat
     1921 gccggaaaac aaagatggat agcaactcaa atgcttgttt gggaaaacag taatgaaaag
     1981 cctaaaagta taactgttac gccaaattgg aaaaacggag ctactaagtg gaaaaatgat
     2041 ttagtggctc gtgcaaatgc tattagagta agaacaaaat gggattctac gtctaagacg
     2101 gttgatgagg gagataaagc aacctttaaa gtaactaata cttatggaga tcataatttg
     2161 catgtgaaat ctgtatctgg tggcggcaaa gctaccataa gcaatggtac tttaactgtt
     2221 gatactacag gagccactgg aaacaaaatc actgtagata tgattaaagg ttctcaccct
     2281 tcagacgcgc accctacaac ggtatggagt aatggttctt atcaaaagct tgttaccggt
     2341 tctttttaca ttagtacttc tgttacggta aatgttaaga gaaaaggaac tgttgaagtt
     2401 ttaaaagttg attcagaaac aaaaaaacca ttatcaggag caacatttag atttagctac
     2461 tcaggtaaaa caaaagatgt tactactgat tcgaatggta aagcaaaatt aactgaaagg
     2521 ttgaaagctg gaactgtagt aaaagttaag gagataaaag ctcctaatgg ctaccaacta
     2581 gattcaagcg aattttcaat tacagttaaa gaaaatcaaa atgttactac cacaagaacc
     2641 aataagaaat ccacaggttc tgtagaaatt gaaaagatag gcgatttaga tggattagga
     2701 ctaccgaatg tagtattcac gatttataat tccgataaca aagttgtaaa agataactta
     2761 aaaacagata gtaatgggaa aataaaagtc gatgaactgc aatttggtaa atattatgca
     2821 gtagaaaaac aaggtgttac tggttatgat cccgatggta aaaaatacaa ttttgaaata
     2881 agtcaagata ctccttttac aaaaccggct aaagtgaaag taacaaatat ttatgaagta
     2941 tccataagcg aaaaagtatc ggacatgaat gaaagtcagg tattaaaaaa taattggtct
     3001 gctgatccaa acgattatct tcaatatgac attacaactg gaaatctaaa aaaatcggga
     3061 gaaagaaacg tccaaagttt cattatcgaa gggttttacg acaataagaa tgtagatgtg
     3121 tcaaaaagtg aagtatatgt tggatcaaca aatgtaacaa actcttttga cattaataac
     3181 gatactaaca atggaaaagt aattgctaag gcgaagacaa gcgtattaac gaataatgat
     3241 ttttataata agtcctataa tttacggatc actatgaaaa ttaaaaaatc tactcttgaa
     3301 aacactgaaa agcaaaaaaa tttaacgatt gttaaaaata gtaaagttac tgtcggttca
     3361 aaaatctcta aatctgctag ctctaatgat gtagaaaccg ttttatattc aagaaaagtt
     3421 actatcaatc atattgatga aaaagacaaa caccttttga aacaagatat tgattataaa
     3481 tacgatgggg aaacgtatga atataaacct agaaccgatt tatttgataa agatggaaac
     3541 aattataaat ctgatgtaat ccataaaggg aaaattgatg gaaaagatat agttttaaac
     3601 actccctatc atattccggt actttctgtg aatgtggatc ggattcaaat tgatacggct
     3661 agagctgtta aaaatggcta tttacctaca aaaatagaac taagtaaaaa agaagaatat
     3721 gaaaaagaat tagaaaaaat tgtattcaaa gttaaaatta cagatataga taacaataaa
     3781 gttgtttatg atgaaaactt taaatacaaa gaatttaata gtcatatgtc gcttgattta
     3841 cctacagaat atttaacaaa gaataaaaaa atcaattata gtgttgatat tcttttagtg
     3901 gataatccag ataaaaacaa gttcgaaact gaaactaaag atttaagaac gatcggttat
     3961 acttcttctg aaaaagtttt aacaaacaaa gatatgacaa ataaccaagt caactattca
     4021 gcagtagtta gaacagtgaa agaaagagag aataataatc cggtcaaaga gttcaatgag
     4081 agtatcaatt ataaatttac tgatagcact aaaacaaaaa caggatatgg tatatcagtt
     4141 gatttagagc caacatatag aaatgaaatt gggaaacaaa tagatatgaa agtctatagt
     4201 tatccgatga atgaattgat tgacagcaaa attgacgaaa tctatcaaag tgggggaaaa
     4261 gaaacagaag ttaagatgga tcgcttaaag aatgatggta aagttgagtc gggtattagt
     4321 actcaaaatc tttcattcca atttccacat atgaatatcg aaagaaaaac tggaaatata
     4381 tatgctgaca gtcaaagaaa tgatgaatct attaagtatg aattgatcga tggcggtaga
     4441 aaattatatg tgcctatttg gtgtgatttg ggaaattatt ctattgctat caaaagtagt
     4501 aactttggtg gtaactatat ctcgttggat atgaaccaga acatagatgt ttatgcttat
     4561 atgtatgcaa cgatagatag tgaaacaaaa aaagatgatg aattactgct tgaacctgtt
     4621 tatccagagt ctactctacc agatggttgg agcaaaaatg agattgattg gctgaataaa
     4681 taagtttgaa aagtttttat ctatctgata gaattaaata atgatatagg gatggtgata
     4741 gaatgagggt tcaaagctat ggtaacagtg tctttgatgt taaaagagaa tttcaagatt
     4801 ctagaagaaa aaccaaaaag ctgatagctt acttcattct atcagctatc gttttctata
     4861 ttgtcaagtt tgttttggaa ttaaactcaa tagtattcac agatatggtt cataaaatgt
     4921 taaatggaga acctattaat ttcaactttg attacatgct tgaaaaagca caaagcaatc
     4981 aaattgtggc ttttatcgtg agtatctatt attttattga aaaatctatt ttttctttaa
     5041 aagatttttt ctttgaaatg cttaccaaac taacaacgtt ttacaataaa atttcaaaaa
     5101 attaaggagg aagtttgaat gttagatcaa aatacagaca gaagttggtg gatgattggt
     5161 gccgtgatcg taggtgccat cttaatcggg acagctaaag tagcttttcc cgaagtgttt
     5221 aatatcgtca ttacattttt caaaaacatg atccctacaa acttaggata gttccactaa
     5281 aaaattcacg tagtttgatg cgtagaaaaa taataaagaa tgaaaaaggc tacataaagt
     5341 gatttatgta gccttttttt tggatggaag tgatgtaatg ctaagagata tgcccaaaat
     5401 gattctttta atgtttgttg ggttcttttt aattttagtg attgcgtact attcattaaa
     5461 tggctataca caagattcgt ctgtgaaagg tatgcaagaa acgttaagaa ctacagcaat
     5521 agcaaacagg gatgatagta ttcgagtaga aaaaggacga tttgctttaa ttaagtctga
     5581 ttttgaaaaa gattttaaag aaaaatttgg gaaaagtaaa aatctaaata atgaaaccgc
     5641 tgattataaa tttgattatc ttacagatgg gaaggacggt attaaagcaa ttaaagtgaa
     5701 ggttgaaagt ggatcaaaag aatatcaagc aacttgtatt ttaaatgttg caaatgatta
     5761 gaggtgtgaa atttgcgtgt tgtagaggaa aagaagattt ctccaaaaat cgaggaaact
     5821 cctaaaagta aaattaatat cgcaagtatt attaaaaaaa atggaattaa agaaaactct
     5881 gaagcgatag aaggaaacct tgatttttta actaagcttt tagaagaaga tagtggaaat
     5941 tatgaaccac caattgaaga tgcaaaatta aatatgattc gtgatgattt aaccagaaac
     6001 tattcccaag aagttttaca agctttaact gatgatgaaa ttaggcgaaa acttgtacaa
     6061 gttgttttga aagaacatgg tactttcttt aaaaaagata aagaggttgc agaatatgta
     6121 gtacgtgaat gtattggaac agggattatt gagcgaatta tgaccaacga tgaaattaca
     6181 gatgttggtt ggaatggctc tcaacttagc attgaaacta actctaacaa atggttgttt
     6241 gacggtgata aattaaatat cacgcaagag tatattgaac gtgttatttc taaatatgct
     6301 gttgtaaatg atcgggcttt taatagtggt aatcctatca tggatggaat gtttaaaaat
     6361 gttcgtatat cagctacaca catagataat tcaccagatg gctctacgtt ttctatgcgt
     6421 gtggcaaggc ctagattagc attgaataaa gaaaactttg aagattttgc tcctgattat
     6481 attttggagc tatttgagaa aatgatgaaa acaaaagcaa atatctgtat atcaggggag
     6541 acaggtacag gtaaaacgga acttcaaaaa ttactgctaa gttttattga taatcatgat
     6601 cgtatgatta tgattgagga cgttcaagaa actcacgcta aagaattatt tccggataaa
     6661 gatattttct cttggatcac tactcccaaa aaagcaattt cagatttagt aaaagcttct
     6721 cttagaaata atccacgatg gatcattgtt tcagaaacac gtggttctga agcttatgaa
     6781 atgcttcaag cggttttgtc aggtcactat gttgtaacga cacttcatgc ggttaatgca
     6841 cgtgcgatac ctagacgttt tgtaaatatg tgtgcaagtg gttttaaaat aaacgaaaat
     6901 gcggttgagg aagacataaa tcgttatttc gattttggtg tccatatcaa aaaaacagtg
     6961 gttgatggta aagtgatccg ttatttgaat gaaattgttg aattttctgc tagtgaaccg
     7021 actacagttt ttaagcaaaa atttatcaat ggaaagtttg tcattgaaaa tggtagtctt
     7081 tccgaagatt ttaaagaaaa aatggctgaa aaatttatta cgtttgaatt tcctgaagat
     7141 caaactaata cagaagaatc acttcctgaa gaagaagagg tgatttaagt tgaaagtaca
     7201 ggctatgaca aagcgaaaag gtctcatgga tgtttcggaa ctaaacgcct atcaagtagc
     7261 gtatggtaaa ccgttagatt atagagatta tttgaactat gttggattac cttgtttgtt
     7321 tatgggtggc ttttcttttg ctttatgtta ctactggtgg attgctttga tttgtggagt
     7381 aattggaggc gtatatggct ttaaagttat aatgcctaaa agtattaaac gctcttatga
     7441 attaaagagt ttacaggaaa gaaataaatt tattaacaac atgactcaaa ttttgaccga
     7501 tgatagtaaa acagttacta gagcgttatc tatagcaaaa cagcgaacaa aaggtgaatt
     7561 aagagaagat attcaaatct tagaatcacg tttacaaggt gctgataaat ttcagattgc
     7621 tgaagctttt cgtgaaatca acaataaata ttatagtgat gttgttttta cacaatactt
     7681 tgagcaattg gaaacagcta tttacgaagg tagaaataat tcagatacta tgaagcaaat
     7741 aaagagctat cataatgatg tgaaacgtaa aacagaaggt tttatgaaaa tcaaagacgg
     7801 ctatcttcaa gatatgaagc aaatgatgtt tattgtagct gtttttattg gagctataac
     7861 ttttgctttt ggtttttcta ctttctatga aggttttgct cgatcaccta tcggatgggt
     7921 atttggatct atttactttt tgattatggt tagcttcatg aagtcatttt tcaaacatta
     7981 ttttgatgat gaaataatga gtttgggggt aagtaattaa tgaaagttaa ggctttaaaa
     8041 aagaaaagaa aatcaagtat tagccccttg aaaattacga aaacagaaca taaaagcttt
     8101 tggattaaat tactaggtga tgtttattat caaaaattac gtgaaatgaa caattccaat
     8161 attgcgatta ttaagtggca aaaacaacgg ttaaaaaagt cattgatttt tatcctagtc
     8221 ggattcttaa tgtatctatt tttagggaaa gaatggtatt acttagccgg tggaattgct
     8281 acttcagtag gtttttatgt ttggcaagca aaatcaatca atggtatcta taatcaattt
     8341 cggtttgaac gacacttgca atttagtaaa tttacacggc tattgatccc ctatctgaaa
     8401 caaaaaaaag atggcggaaa tttatatggt gtttttgcaa aaatcgtaaa aagactagat
     8461 tatgataccg ataaaaagct attaatgaag cttatgcaag aaatgacaga tcagcctaac
     8521 gatattagac cttttacgga atatgcagaa cagacttctg gaacagacat gtccgtatta
     8581 tttatgtcta cagtttatga tattcgacaa ggttcggcag atttggatgt tattgaagag
     8641 ttggatcgtt tagcttctga agagttaatg gccggaatcg attcaatcat tgactataag
     8701 tcgaggcgtt ttgtcttctt tcctacaaaa attgcaatga cttcatttat tttagttgtc
     8761 ggttttgcag taggcgttct tttcatgaac ctaaaagata ttaactttgg gcaataaagg
     8821 aaaggagaaa gtcaatgcaa gaacaatccg ttatggaaat cattaaatgg tttataggtt
     8881 taatgatgat tatggcaatg gtttctatag gacttttttg tgttcaatta caagatatta
     8941 atactttcaa gcaacaagta aattatcaaa ttgaacgaaa aggaggtctg acgacagaag
     9001 ctgttgaagc aatcgacaaa tattcggcta ctaattatga tagacgtttt acaattgaaa
     9061 gcgataagtt aaatcagaaa gtatcttatg gagaagaaat tgattatacg atcaaagcaa
     9121 ctattccaat tcaaatttta ccgcttcctg atgtaacttt atcgtttaac ggaaatagtg
     9181 tttctcaaat aagatgagag gaaggataaa atgcaagaga ataatgtttc cagaataatt
     9241 tatttgattg gcggattgat aattttatcc ttagctattg ccggtcttgt agagcattgg
     9301 ccggaaataa agttattaat aagaaacttt tacgacaata aaatgattaa aatgtaggag
     9361 gtatagattt ggaagcaatt caagaaaatc gtaaggataa tcaagaaaca agtgaaaaaa
     9421 acaaaaaaaa aagaaaaaag aaagtagata aatttacgga aatgaccgat aaaatcattg
     9481 aaaagaaagg acttaaacct aaagactttg accgtcaagc aatcaaagaa gcacgacaaa
     9541 aactgtatga tgattttgtt aaagaaaaca tatcacagct tttagactaa catttagggg
     9601 gaaataaaat gaaaaattta gttatcagca agtttgcaat gttaccaaga atggattttt
     9661 tcgataatgt aagtaagttt atgtcaaata tgacttcaaa actacaagga atttcactat
     9721 ctgtaattat cttttgtatt gtggttactg gtttgatgtt tcttttcgga gaagggccaa
     9781 gtcgtactgc taaaaaatgg ttaacttata tcgtgattgg ggcaataatt atcttcggag
     9841 cttcaactat cggacaaacg atcaagtccg ttggtggttt ctaaggggaa gcttcttaga
     9901 actaaaaaat tcgcaagtat tgcatgaaag agcattgagt gattaatgct cttttttatt
     9961 ttgaaaaact ataaactaag gagatttaaa ctatgaacca acgattcgaa tataattttg
    10021 aagatgtaga acctaagtta ctgaaaaaag gaaaaggatt aaaaaagaaa aataaatata
    10081 ctctcaaaca agcagaagca ttagtaggat ggattcaaca caattggtca gacaagacaa
    10141 caattacctt gatctgttca gacacagaag aaggaacaaa gtatgctttt gatggaattg
    10201 aaattactcc attttcgatt ggcggacaag aaaaattatt gtttcctgat attgaaggac
    10261 aaattttaca agcgccggac agcatgattt ccgatcctaa taaactgatt ttggatatta
    10321 acgatcaata caaacacgaa ccagacgtag cagaaccaac aaaagaatca aagtcaaaat
    10381 taaatttgaa gctcccttca gtagtattac catttgctaa gaagaaaaat aaacttatga
    10441 acgaattgat tgaaccagaa gaaacggata tttatgaaga agaattagaa gaacaagaag
    10501 agatcgaaga attagttgtg tcttctgaag aaacagaaga agtagaagaa attgaaactg
    10561 tttctgaaaa tgaagaagaa acagaagaaa tctttgactt tgaagatgaa gaagaagtgg
    10621 aaaatgtaca gaaaggcgat ctatctacaa gtagtcaaaa tgggttggaa gctgtaaatg
    10681 atccacaagt tccaccatat atatcttcac aaactcccaa ttactctcca cagtatcaag
    10741 cgcctaatgt cttacaacca ttaagaaaac acgaaacagt gcagttagtt acgcttaaag
    10801 agtactgtga tttgggagaa gaaattgaaa cttcaatttc tcaaatggtc gaaaagttga
    10861 aaccagaatc tttattcaaa ttcataggga ttccttctac aggtcttaca aatactcgta
    10921 ttgatgaata tagaagtaac catgctatgt tgcgattagc tgaagtaaaa tttgaaaatt
    10981 taagagagca ttattcacgg caaattattt cttttaaagc agaagcccta gatcgtttaa
    11041 gaactgcggt agatattgct tggaagaagc cttacgattt agatgtgaag aaaaacaagg
    11101 ccgaagagtt atcaaaaatg gaagcagaag cagaagctaa attaaatgag ttcgtgaaac
    11161 gtcaggaaaa caatgtaaat gataaaatca aaaagtttga gatcgaacaa gaaatagatt
    11221 taaaaaactt tattgcaaga caagaggcag ataaagcggt atttattgct acagagaaag
    11281 atcggactca aaatttaatt gattctaaag cggaatcaat caatgcagat ttacttgaaa
    11341 caaaagataa atttattgat gaagaaatgt acaaaatgaa aattgaaatg aacaaaaatt
    11401 tatttgatgg caagcaaaaa attaaatcag aattggctac tgaactcgct aaggcaaatg
    11461 ataatgtttg ggaaaatgcg ctgaaattta ttcaagaaat tcaagatgaa attgaagcta
    11521 aaacaccaat ttgggctgct gaaatcaagg agtttaatag tttagaagaa caagaacatg
    11581 aacgtatgaa gcaaactaaa gaacttcaat taaaagagga aagtattgaa atcaagcgtt
    11641 tggaagctga aatgaatttg aagcgtatgg aagaattaga tcatgaaaat aaaatgctta
    11701 aaattaaact tgaaactgcc ctttcaaaaa atgagttatt agctatggaa caagatacaa
    11761 agcaagtggt gaatggatca aacagagttg gtgcacttaa tttatttagt aaacgttaaa
    11821 ggagaacgga tatgagtgtt tttaataata aagttatgtt agggaactgt tatgtgaacc
    11881 acattggttt ttacgatgga ggaacataca gagttttatt cttacgttta tctgttttta
    11941 gttactcaaa agatggaaag gggcattatg aaaatattaa tgcacaaatt tcttgtcctt
    12001 tagatagaaa tggggaaacc acgactacaa gtagtcaccc taaagccttg atgaataaat
    12061 ttatctttga aaagttggat cgcaatttgg ttgaggggat gaagataagt attcatggaa
    12121 atattcgtgg aacagaacaa gtgcttctta acagtggttg gaaaaacttt ggtcaattat
    12181 cgcctttaga aaaagaagaa tatcaaaaaa ttcctaaaaa tgaattagta acaagaaatc
    12241 aaacatatat ctatatagaa gaggtaagta tgccagaaaa agaagaattt agaaagtctc
    12301 aatctaaggt aacaaaagaa gatgtggaag ttgcagaacc gaatcaagca gatgaaattt
    12361 tatccgatga tactgatcca gtgaatgatg aaggagaggt tattgaagtt tttgaagctg
    12421 aaattatcga agaggaagaa gaaattaaaa gttttgataa aagaatgtat cgagagaaac
    12481 caaaaggtta tgtgaatttt gaagatatgt attatgacga atattctaat gaaccaccga
    12541 tcaattagtg ggggtcaaat atgaagctag tacaaaacaa tgaagtgaaa gaaataaaaa
    12601 acggctttgt taaaaactcg aacaaaattt tgggaaagct gaaaaaagta ggtagtttca
    12661 aaaaaaataa atatcatact ggaaaaattg agggagaaga tttaccaaaa agtttacaag
    12721 ataaattgaa tgttccgctt gtatttatag gtgttttttt aggttcaata gtttttctag
    12781 caataacgta cttattgaac tttttaaaag ctttgttagt tgcaatcgga cagtcagaaa
    12841 gtgggctact tggtgtagag ttcgatccta agtttagttt ggcatatcta aaaccacttg
    12901 gggatacgaa acaatacttt atgtgtgctg tggttgcggt aataggagtc gcttatttaa
    12961 tatatgggaa attaaatcat gaaagtgaga aaaatcttgt ttacggtcaa aaaggagatt
    13021 caagactttc aactatcaaa gaaattaaga gagattacca tgagatacca gaaaaaacag
    13081 aagtgtatga tggtattggt ggtgtgccaa ttagtcacta tcaagataaa tattatattg
    13141 atagagacac agtaaatacc gttgttttgg gagcttcacg atccggtaaa ggggaaacat
    13201 ttgttgttcc tttattagat aatcttagcc gagcaaaaat acaaagtaat atggtcgtga
    13261 atgatccgaa aggagaattg tttagcgctt caaaggaaac acttgaaaaa cgaggttatc
    13321 gtgtattagt gctaaatatt gatgatccac ttgaatcaat gagttttaat cctttacaac
    13381 tagtaattga tagttgggct aacaaggact atcacgaagc tagtaagcga gcgaatactt
    13441 taacttcaat gctctttgct tcaggaatga gtacagataa tgagtttttc tataaatcag
    13501 ctaaatcagc ggtcaatgcg attattttaa cgattgtaga acactgtttt aacaatgatt
    13561 gcattgaaaa aattacaatg tacaacgtgg ctcaaatgct gaacgaatta ggaagcttat
    13621 tttacactga tccaaagact ggaaaagaaa aaaatgcttt agatgaatat ttcaatactt
    13681 taccacaagg gaatcaggcc aagattcagt atggttctac ttcatttgcc ggtgataaag
    13741 ccaaaggttc gattttatct actgcttcac aaggtattga aatgtttaca agtgatttgt
    13801 tcgggaagtt aacaagtaaa atgtctattg atttgaaaga gataggcttt cctaagtcca
    13861 tacgatttaa agtcaatacg aatttagttg gaaagaggat tagtatttca tttttgagaa
    13921 aagaaaatga tgtaattaga ttaattaaga agtatcgagt gaaagtaaaa gctttagggc
    13981 tatgtgtttt aaattttaat gaatatcttc aggatggaga tatgttggat atacgatatg
    14041 aagaagagaa atcgagagca tggtatcgta ttgaatttcc caaaaaacaa gcaaatagtc
    14101 atgatacttc tttagtcact aaaaaattca agtcaggtaa aaattattct gacttagaaa
    14161 tcagcacctt acgattaaaa tacacggatc agccaactgc tgtgttcatg gttattccag
    14221 attatgatcc gtcaaatcac gtacttgcaa gtatttttat cagtcaactt tatacagaat
    14281 tagcaagtaa ttgtaagcaa acaccggata aaaaatgttt taggcgagtt catttcttgt
    14341 tagatgaatt tgggaatatg ccggctatag acaatatgga tgggattatg acggtatgtc
    14401 taggaagaaa tatgcttttt gacttagtga ttcaatccta tagtcagcta gaaacaagat
    14461 atgataaagc ttttaaaaca attaaagaaa attgtcagaa tcatatttta atcatgtcga
    14521 acgatgagga aacgatagaa gagatttcaa aaaaatgtgg tcataagaca acaataaata
    14581 gaagtgctag ttctaaacat ttagatactg atagctcggt cactagttcg gcagagcaag
    14641 agcgagtaat tacagttgag cgtgctagtc aattgattga aggggaacaa attattttaa
    14701 gaaaccttca tagacaagat acaaaaagaa ataagattag accatttcct atttttaata
    14761 ctaaagaaac aaatatgccg tatagatacc aatttttagc agaagacttt gatactcaaa
    14821 gagatattaa tgagattgat attgcatgtg aacatatcaa tctatcttta caagataacc
    14881 aaattccata tgcaaggttt atcaaagatt taaaaacacg tttggagtat tcaattatta
    14941 ataatattcc tattagtgaa gaagactatc aggattatct aaatttatca ggatcacaac
    15001 aaacaattaa tgaagaagag ctgttaaaac tggtaaatac ggaagtaaaa agtcaagata
    15061 tggaaggtca agttttatca gaacaagaaa tgaaaattaa tatttatcta aaggaaagtc
    15121 aaaaggaagc aatagaatta gtaaaagtaa ttaatggaag gttagctgat gaaaattcag
    15181 cagatatggt tataaaaacc attaattcac aaatccttga tacgcctttc attcaatctt
    15241 taatcaatga ttctatagct attcataatg ttcaagagag taaggatcaa attatgatcc
    15301 tagaacaaca attagctaat gcttatgagt tagcagtgtt taaaacgaaa aattcaatac
    15361 tgaaaaataa aattatcaag ttgaaaaatg ctatgactaa gctagcaaaa gcaatttaga
    15421 gagaagggaa gaaatattga ctgaatctat taattggaga aaactaaatg tgcaatggtt
    15481 aaagtataaa tggccaatca tagtttccct aataatcatt ctatttatgg cctatccgca
    15541 acgagttttt gcgttgccgt ggattacaga caataaagag gtattaaaat ttttaacaaa
    15601 atatcaagat tatcttcagt ttactaaagg tggttttgga agcattgtcg ttcaaagttt
    15661 atcgtggggg ctgattagag gtgcatattt tgtttgtaaa tcagcagaaa accttgttcc
    15721 acaatcgcta agtttgttta gctttgttga aagcagtagt ttaggtgctg tttatcaatc
    15781 tgtattaaac acggtggttg taggattaat gatcctttca ttgatgtttg ttggttacaa
    15841 gatgattact ggaaaaggaa cagtggattt aaaatcggtt ggaatgaacg tagtgatgtc
    15901 tatagcatta atacttttaa tgccaaccat gatttctagt ggtattcaat ttgctaaaac
    15961 attttataag gactctacta cgattacaaa agctgatggg ggcgttgctt ggtcattgat
    16021 tgaggatggt gtaactgatt tagtatatat caataaaaac gatgcttatg atcggttggg
    16081 taaagatggc gtacaaaaaa atgcgttaaa agaaaagaat ttcttttcct atgatttcag
    16141 tgaagtaatc acagttgata cagctaaaga tttggaagat gataataaaa aagctgaata
    16201 tcttcaatct aggttgacac cagacggtga aggaaatatg caagccgtta agattgatga
    16261 tggttggatg tcgatgttct ctgatagttt taaaggaggg tactacaggt ttactaaaaa
    16321 tacttttgca ttgactttag gattgctttc attagctgta gcttatgttt ttagtatttt
    16381 tatcatagtc accgctattt tagaactggc atttaagcgt gtgttagggg ttcttgtttt
    16441 tgcaacagat attgagacag gacagcgttc aaaagttgtt ctatcagata ttctacagtg
    16501 ctatttgact gtaggatttc aaggatttgg attatccatg tttgcaatgt ttgtttccta
    16561 cttaggaaca ggcggagggt cttctgttaa tccgtttatt aaggctgtag cttatgtatg
    16621 tgccgttttt gttttaatca aaggcagtgg aacagtcatg agatactttg gtgttgatat
    16681 tggactcaaa gaaggctatg ggcaacttgc ttctgctttt ggaatgggcg caatgctgtt
    16741 tagaaaagga tcaaatggat ttaatcgtgc taaaggaagc ggaaatggaa atggatcaga
    16801 cagcggagaa ggagaagatc gaaaaccaga aaagaatttc ggcgaaactc tatcaaaaaa
    16861 agctggcaaa actggaagag ctttgggata tgctcatgaa cgtggattat caggtttagc
    16921 ttcagatgga gctacaatag ctagtgaaag agcaacaaaa ccatttaaaa gtatgcgtga
    16981 tatagctaat gataccaaga ataagttcaa agaaggttta gatgatggta cagtgtccgc
    17041 tattaataaa aatagcaaac ctatgttagc taaaaataaa gaagatgaaa ctggaaaata
    17101 tgctgattcc atgccaacac gtctttcgga tagaaaagat ggtgctaagg ttgaaaatgc
    17161 cgataggatt atgtctagtt ctgaacgtat gcgtgaagca atgaaaaata atgctgaatc
    17221 gaataataat cctgtaagtg caattcagca aaaagtccaa caagatattg aagaacgtaa
    17281 aaatgctatg cacggtcaag ctaagtctgc tgaagaatta attaatcaga agcgacagga
    17341 agcgaaatac acgcctgaag caatgaatcg tgaggaaatg ttaaggaaac gtgtagaagg
    17401 gcgtacaggc gctaatatgg acgaaaaaga agcgttgacc aaagaaagaa tccaagaagc
    17461 taaaaattca aataccggat tagaaaaatt ggtcaaagaa aatctacaaa attctacaag
    17521 tagtcaaggt ggccgatcag tagatgtccg agaaaatatt caaggttcat tgaatggtca
    17581 tgtcggacgg aatgttgatg taagagagaa tttacaaagt tcttcaaatg gtcaaggtac
    17641 taagacaatt gatgttcgag aaaatctgca aagtagtagt acaagtcaac caaaaacagt
    17701 agatgttcga gaaaatgtac aaaattctac aagtagtcaa gactttaaat cagtggatgt
    17761 ccgagagaac gtgcaaagta gcagtgcaag tcaaccaaaa acagtagatg tccgagaaaa
    17821 tgtacaaagt tctacaagta gtcaaggatt caaaacagta gatgttcggg aggacgttca
    17881 aaaagatagt ggagaaatga aagaaaaaac acaaaaaatc aatatcgttg aagacagaaa
    17941 gtcagcgaaa agatttgatt caaatcatga aacagtgatt attgatagtg aaatccgtga
    18001 aaatgataag ggatcaaaac caagacgaag attcacttat gaagacaacg agttattcag
    18061 agatacactt aatgatccta atccactttt cgataattta aattaaatta aaagccggca
    18121 tgagtgatta tgccggcttt ttatgaggtg aaaatgatgt atagaaatcc caaaaatata
    18181 aaacaagaga taaagctatt tttcttctat ttagtcgatt taggaatagt agccggaagc
    18241 gtgatggcaa gtgtttactt tgcaaaatta ataccaattt caccaatgat gaaatttgca
    18301 ctgtacttat tagcatttgt agtgggtgtt tggatgtgcg ttagaacgcc taatcaccct
    18361 aaagagcgaa atattttaat gctgtattat ctctttaaaa tggatagaaa cagataccac
    18421 gaagtagagt ttaaaagaaa tagtaggggg aaaattgaat tatgattgtt gctgaaagta
    18481 atgaaaataa attaagtggt gttcttgaca aattcttaga actagttatt ccaaaagata
    18541 aagatatgtg tgaactttta ccatataaaa aaatattgaa agacggaacg ttagtgacta
    18601 atgacaataa gtatcaagcc ttttttaaag ttaaaacaac tgacttaact tctatttcag
    18661 aagatggatt tatgcgtatg gtaaacaaac tcacttattt aaaccgagta tatttagaac
    18721 catataaaat ttattcatta acttatccta ctgaaacagt aaatcaagcg atttattgga
    18781 agcatagaat acaggaggca aagagaagtt tattgagtaa taatgatccc aatttagaaa
    18841 cgtatctgaa gtggaatcta aagctagctt acgataatta tgaaagagtt gatctagtat
    18901 cgactttacc agagttgatg ttcgttattt gtgtttatgg aaaaacacaa aaagaagtga
    18961 aaaatcatgc cgatgtaatg aaacaggccg gtggtagaga attagattta caaagaatta
    19021 ctgaagggga tttaatcaat gtgataacta aattgatgaa tcccaatact tctttataag
    19081 gcggtgctta ttactatgtt aaagcactgt agaaaaggat tttgtaaagt aattaaaggt
    19141 aaaaatgctg ctgatttaat ctttgaatgg aaagaatcta atttaattaa tgtacgtggg
    19201 aaaaatggaa gcggaaagac agaaagagtg atggctagta ttgataattc aaggcctaga
    19261 tcaagagcat tagtaataac tgatgaaaag aatcactata aaggcataag aacgatagaa
    19321 aaaaaatatt taactaataa tgatttaaaa gtagtagatg atattttaaa tatttatcct
    19381 gattttaatt tagttgtttt tgatgaaaca attcctgtga cagaaataaa aggattctat
    19441 caaagctttt ccaatctagc aaataaatat gaggaagttc tgtttgtttg gattacagaa
    19501 gaaaatagta atagcaagtc agcgttcttt agtgaaaaga acgctttttt acattctatt
    19561 taaaaaggag aattgaacat gattgtaagt aaaaaattag caagaaatct agtaagtgaa
    19621 gggtatgact taagattagt agaaaagtat caaccgagcg gtggaattaa atttgatgag
    19681 cgttatattt ctactggtga tggatatgta acttcgattg ctgttattga gtttgcagaa
    19741 gatgtaaata gtcgatggtt aacggatata atggcaattc caaatactat tgcaactttc
    19801 gatgtatgta cggcggataa agaagactta ttacacaaaa tcaatacgtc tattggagaa
    19861 ttagattacc gatcaacaaa tgagaataga acaactgaca aaacagacgc tttactagat
    19921 aaatacaatt tagaagattt tgcacaagaa attacgaaac gtggtgaagt tgtcaaaact
    19981 gttcatgctc gtatttttgt ttatagcgat tctttagaag aattagagaa aagaattagt
    20041 gagattcgta aagatttggc tagtgtcaat cacaaggcaa ttgttccgca atttagaatg
    20101 aaggatgaat ggatgtcttt atttcaagat ggcatggaac aagaatcaaa attatttgcc
    20161 aagaaaggct taactgttcc ggcaaaaaat attggtggcg gtattccatt tcaccacaag
    20221 agtttgaaag atccacgtgg gttttattta ggaactacgt caactggtgg tgcttttata
    20281 tttgatccat tttattctac gaagcaaaga cggtcgttta acggctttat tttaggaaag
    20341 atgggttttg gtaagtcaac tttaattaaa cagctacagg aaggcctaca agcgaaaaat
    20401 tgttttattc gaggatttga caagtcaggt gaatttgaag gcatggtgaa gaaagcaggc
    20461 ggtgtatacg tcgatttagg cggtggtgat atggtagtaa atccattgca aatttatgca
    20521 acagtcatga aaaaagatca atttggaaat gatgttgtag atgaatcaaa gagttttcaa
    20581 aatcatatca ctaagtgtag taatcaaatt cgctttttag aacctgaaat tgatacggca
    20641 actgtacgtg aatatacttt gatgttacaa gacttttata ttcattatgg aattttgcca
    20701 aaagaatgga gagaagcgag agacgacaac gaacgaaatc aattaaatac aaatatttgt
    20761 aacttgccta atgattcata tccaatctat ggagagtttc ttaaatttat tgaaaatcaa
    20821 caattcaaaa ttaaaaatgc tactcctgaa cgtgtccgtt ctattgagct aattaagctt
    20881 atcgttacgg atatgtgtac aacttatccg caaattttca acggagtaac aacaatgcca
    20941 aactttgata caacaaaaat tgtttactat aacattgatt ctattagtaa aatgagtgcc
    21001 ccagtattcc attgccaatt atttacagcg ttaacgacta tttggaacag tgccttgcaa
    21061 aacggaaaga ttcaaaaaga aaactttaaa aaatatggca gtgattatta taagtatgca
    21121 caagatttca tggttttgat cgatgagtgt ca
//
LOCUS       DACDLM010000050        20927 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.050, whole genome shotgun sequence.
ACCESSION   DACDLM010000050 DACDLM010000000
VERSION     DACDLM010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20927
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.050"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            700..2610
                     /gene="ltrA"
                     /locus_tag="IV356_001887"
     CDS             700..2610
                     /gene="ltrA"
                     /locus_tag="IV356_001887"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAP9015574.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            2714..2938
                     /locus_tag="IV356_001888"
     CDS             2714..2938
                     /locus_tag="IV356_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015575.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLNLFNRIVGA"
     gene            2951..3454
                     /locus_tag="IV356_001889"
     CDS             2951..3454
                     /locus_tag="IV356_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAP9015576.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKEQIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCNLAEELEGTPIGEAASEIQHAFFNSFEEMVEH
                     VDDIVYYPDCDDMSDVAHYLIVEAGDFGEVPEQLKPYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPE"
     gene            3581..4618
                     /locus_tag="IV356_001890"
     CDS             3581..4618
                     /locus_tag="IV356_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015577.1"
                     /translation="MANIQTSFIDFHNSIRLDVEDNTLLKDYKDQVIDGLKDYLPDDV
                     KFETFLQGSYSVYTGIKSCDEKIDFDIDIAVAFEIDHTVYEDPREPKLWVKEALVEIF
                     PNAQVNLKVPCVTATFTGKKTKKNVHVDVAVYAKEDENYFLAKAKEFSAPENRCWEEA
                     DPKVLKEKINSHVADSDDRKQFRRCIRYLKRWKDNNFNQEYKPTGIGLTINVMDTFLV
                     NKSTDFLTRKVQYNDMECMKQIVSSLKDSFVYEYSETDGWHYRLHAYLPVKPNSDTYS
                     KMTVNQMSDFKNKLSKLYDDLIFAIDTEDEYEATKRLNNQFGEDFLIISEEEVTEKNL
                     RNAFVTDYPSA"
     gene            4633..6330
                     /locus_tag="IV356_001891"
     CDS             4633..6330
                     /locus_tag="IV356_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HAP9015578.1"
                     /translation="MDYTDILKEKLTDVVRLFDGNYYGDFSFATIGKLRLKIEIPKHF
                     PLVLPRIYIHNFDHLGLYLPHVEKDGLVCFSSDINYLVDEENSELVLLQCVNKTIKTI
                     EEGLKGLNKNDFRKEFVAFWDKQENQISLFYLCEPALFIKSVDTIMYGKSLVALDKEN
                     ELQLNAASRLFNGEKEDTHELDAYYVPIRNKNNIMPPKNNKAWSKKDILQIVKKNVTG
                     ANKRFFLKLEKRKNRHNVLLILDIPIEEKSNNVIIGFLFTKQSGSIKDYKGTPRTVLV
                     QRHDELYLVNRTSGENYGLGANIAIVGVGSVGSKIAENLGPLGVRKMTLIDNDCFQAE
                     NLYRNSLGADSLKNARSQNNFFKVDLMQEELEKKFPYLCVEVESMNVLDLISMQPGFF
                     KEYDYVFVCIGDTMASLALNNYFSKSSQKVFYSWLEPYGIGGHTLFINYSLNQKGCFN
                     CLYTDSNSKNRCSNRASLVKEGQIFERTLASCRSKFIPYNAIASTECAINAIKLFHKV
                     NQNNMTNSTLFSWIGDGSTFENLGYQYSDRNTFLNGVNKFEERFFSKYCKVCGELDD"
     gene            6323..6784
                     /locus_tag="IV356_001892"
     CDS             6323..6784
                     /locus_tag="IV356_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015579.1"
                     /translation="MIKFSCDRIVIEVRDEVLKIFEQYRQGKDDLPEAGGVLHGKRLK
                     NGSIIITDITTPQIGDIQKRLLFKKNREIHQQLSNEKWIESNKFSIALGEWHTHPEAV
                     PTPSNVDKKSWRLNVSKQHDDRVYVFIIVGFSDLRMWLLSKKSDIRQAIKL"
     gene            6797..7657
                     /locus_tag="IV356_001893"
     CDS             6797..7657
                     /locus_tag="IV356_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015580.1"
                     /translation="MKSQKNIWWWGFLVGKVMIPALLLISLPMITFFFTNKKMSKEAV
                     IFFFGDQKATFIETLVTSLQLNLNYIFSIIIVISLLNFFKKRNSGKVFNSNGNVYYNY
                     FYFVFWVAATLLGYDKIQIAGIPIHMQYKLVLSGIFSEVLPDIYDDHYDSDGTCKVSI
                     EKENFDDIDGYDSVNLLIIDTYDIKMSELSMENQTYPTIIVRGNSIDGVRKVNRSLIL
                     EIKKTMDEIQKSDFKKVFVASTSNPKNSINIINSSFRFFGRSRRFKLYVLQKDYASNG
                     KYSKKYRIFI"
     gene            7695..8084
                     /locus_tag="IV356_001894"
     CDS             7695..8084
                     /locus_tag="IV356_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP9015581.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLMFV
                     IVFAHVPPLSMIEGAFLKYLGIPIAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            8071..10518
                     /locus_tag="IV356_001895"
     CDS             8071..10518
                     /locus_tag="IV356_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP9015582.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDLQTDALVSMI
                     GDSQIDYRFFIGFKLISTDEEVNLKNLRKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVKRVTPSDLTYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPTRCLIEEKPRYLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAKSVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HKEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALASAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVIVELRKEDSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDKEDESNQKCMRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            10523..12631
                     /locus_tag="IV356_001896"
     CDS             10523..12631
                     /locus_tag="IV356_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP9015583.1"
                     /translation="MKKKLFRIFGIVLISLVTLIILLSLVGTVAEATGLVDDTVGAGN
                     LYSQYSLGNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEVGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMNMFNLQSNDSQSMGRRVMRKPQMLMNRTLR
                     QLNRNVGRTLAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEIPSDLNKEK
                     PIPNNKKQSRMNLAGRKVGKVLDTQALVKDKTKQVKDGVRNTPTNLKYNFHKGIEKTK
                     KAPEEFKRGLVQEKANRGELREKQQQRRDEKIAEKRKVLNEIGNPHGKRRENVPIKAK
                     VQSQKDRAPKRIVRANSNPEIKRKFASQEIISKGINQSSSKKNSFQQVKRRSTLSKRT
                     NRKVQKSLNPHPKPRSGEKK"
     gene            12628..13632
                     /locus_tag="IV356_001897"
     CDS             12628..13632
                     /locus_tag="IV356_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAP9015584.1"
                     /translation="MNVKKLSAISLTFLTISFMGILMCVGLLFGEDSEGSSSSGAPPG
                     GSSVSEEVLKHRAMVEKYAKESDITEYVPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNFGGGYLDYVAKNGKKHSFALA
                     ESFSKEKSCGQKIDYPNPIANKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSRPETGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTESYWQQHLIGAGRYK
                     "
     gene            13651..14562
                     /locus_tag="IV356_001898"
     CDS             13651..14562
                     /locus_tag="IV356_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP9015585.1"
                     /translation="MKIKIERNQKEKSLKKKKERVVSVGKHRKMVLALWLLLSCSLTF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGIENFTKDFSKEYFSWKNNKEAIEKRMNNL
                     EQYLTEEGFALSQDMVRADIPTNSEVQSVKVLDVEKSSEEFVVSFLVEQKITEGKKAQ
                     SISSAYRVTIFEDENRNYIVTSLPTMIAKPDRAKYKTKQVENDSKIDAKTTEEIAEFL
                     ETFFKLYPSASEKELEYYVENDAMRPINIDLKFSKLEDPVYLQNGKKILVSTKIKYLD
                     NVSKTTSYFQYKLILQKNGNWKIIDVK"
     gene            14749..15036
                     /locus_tag="IV356_001899"
                     /pseudo
     CDS             14749..15036
                     /locus_tag="IV356_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(15224..15439)
                     /locus_tag="IV356_001900"
     CDS             complement(15224..15439)
                     /locus_tag="IV356_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015586.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(15698..15865)
                     /locus_tag="IV356_001901"
     CDS             complement(15698..15865)
                     /locus_tag="IV356_001901"
                     /inference="COORDINATES: protein motif:HMM:NF018933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP9015587.1"
                     /translation="MGSECGHTDGKKSFTIREWTCPICRTHHDRNVNVSINILIKGYV
                     YKHCLRKHQEP"
     gene            complement(16210..17649)
                     /locus_tag="IV356_001902"
                     /pseudo
     CDS             complement(16210..17649)
                     /locus_tag="IV356_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172772.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(18197..18868)
                     /locus_tag="IV356_001903"
     CDS             complement(18197..18868)
                     /locus_tag="IV356_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HAP9015588.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRYLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCQCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEKWIAYITLK
                     KRGTI"
     gene            complement(19217..20668)
                     /locus_tag="IV356_001904"
     CDS             complement(19217..20668)
                     /locus_tag="IV356_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAP9015589.1"
                     /translation="MKKSLKLASAVILMSQLFIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTLSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSAESSTTSSSTSEITSSKVTRPNHIESSKKEAPKTEGQTKNFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            complement(20780..>20927)
                     /locus_tag="IV356_001905"
     CDS             complement(20780..>20927)
                     /locus_tag="IV356_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="pyridine nucleotide-disulfide oxidoreductase"
                     /protein_id="HAP9015590.1"
                     /translation="GLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGL
                     NIET"
BASE COUNT         6994 a         3471 c         4066 g         6396 t
ORIGIN      
        1 aaaagctaag gcactaataa aagaacgaaa aagtttggtt attaggagaa ctgataatct
       61 gacaggtgga atgatgaagt aacgctctga aacgcctgcc ctgagcctcc gacaagcatt
      121 gtatgaggaa actcagaatg tttgaagctc ggtaaagacg gctgaaagat accgtaatag
      181 ttgatgaaca tatatcttct atcgaaaact atccagaggt gggtagcgta tccaacaggt
      241 cgggggtcta taaaatatct atggttagaa tgttctataa ggaactgacg aaacagcgaa
      301 tgtacgggtc taaatttgaa ctttgtagaa atgcaaaggt acgagaaatc gtagctggtg
      361 tggcaaagta agaatatagg ttatgaaatg ccatataacg ttacaggcgg tatcaagcca
      421 gcaggcttat agctagtgac ctaaggatat atatgtatag ataagattat cggaacgagg
      481 aaaggtattg ggttctcatc aagagaataa actgacgaag aacaataagc agttgaacta
      541 atgctgaaaa gcagagggcg aacctaagaa attcttgtaa tgagaatgga ggaatgccct
      601 caagtcgtgt atatattaga aaagtattat gttgtttcaa taaggattac gagtaagata
      661 aaaaagctca ctcaatttca agtaaaggag tgaagcctta tgcctaaaaa taaaaatgaa
      721 acattgtgtg tagaagattt aagacacgct gaatattacg aaatgcaaaa cacctttgat
      781 gatttatatg ccaaaagtaa gaatggagat attttcactc atcttatgga tattatccta
      841 tcgagagaaa atatattact ggcatatcga aatatcaaag caaatgcagg cagtaaaaca
      901 gcaggaacag acggtacaat aattaaagat attggcaaat tgccagcaga aacagttgtc
      961 aaaaaagtaa gatacattgt tgcaggcagt ccacatgggt atcgacctaa gccagtgagg
     1021 cgaaaagaaa taccaaaacc aaatggtaaa accagacctc taggtattcc ttgtatgtgg
     1081 gacaggctta tacaacaatg tataaaacaa gtattagaac caatctgcga agctaaattt
     1141 agtgaaaaca gctatggttt tagacctaat aggtcagttg aaaatgcaat aaaagcaacc
     1201 tataaccgcc tacaaatcag ccagctacat tatgtgattg aatttgatat taagggtttc
     1261 tttgacaacg tgaaccattc caagctgata aaacagatat gggctatggg aatacgggac
     1321 aagcacttga tattcatttt aaaaaggata ttaaaagctc caatcaaaat gactaacggt
     1381 acaataacat atccagagaa aggaactccg caagggggaa taatatcccc actactagca
     1441 aacattgttc ttaatgagtt agaccattgg gtagaaagcc aatggcagga aaatcctgtt
     1501 acaaaaaact atgtggttca tatcaataaa agcggtagcc catgtaaaag caacgcttac
     1561 aaagaaatga agaaaacaaa gttaaaggaa atgtatatgg ttcgttatgc agatgatttt
     1621 agagttttct gccgctacaa ggaaagtgct gaaaaagcca aaatagcaat cactcaatgg
     1681 attgaacaac gattaaaatt ggaagtatca caagaaaaaa caagaattgt aaatgttaga
     1741 aaaagatact ccgactttct tggtttcaag attaaaatga taccgagaag aaagaagtta
     1801 gttgttaaat cacatataag tgataaacaa ttcaaaaacc aaaaagacaa gctggtatca
     1861 caggcaaaga aaattgcttc tccctcaaaa gggaaaacgg aattagaaga aacaagactt
     1921 tataattcaa tggtattagg tatgcaaaat tattatcaga ttgcaacgaa tgtaaatctg
     1981 gattgtatga aactgaatag agctgtaatg gctatcttca ctaacagatt aggtacaaac
     2041 aaaaggggca gattgagaaa aacaggcaga caacttacga caaaggaggc aacaagatat
     2101 ggtaaatcta aaatgcttcg gtatgttgct ggcgagggcg aacctatttt ccctgttgga
     2161 tatatccaac acagaaaacc aatggcaaag gtgtatttag cgaattgcta cactctagag
     2221 ggaagaaaat ttatccacac caatctaagt gttgataaat tactgatgta ccagttaatg
     2281 aaattatctt tggaaaatcg cacaatagaa tacgcagaca atcgaatttc gctattttct
     2341 gctcaacatg gaaaatgtgc tataactctg gaagaatttc aacaagctaa tgaaatacat
     2401 tgtcatcata ttgtaccaac tggagctggt ggaaatgacg attataaaaa tcttattttg
     2461 gtaaaagagg cggtacaccg tctaatacac gctaaaacag aagaaacaat acaaaaatat
     2521 atagctctat tgaagctaaa taaagtccag ctcataagac taaataaata tagagtatta
     2581 gctggcaatc aagaattaaa cttgatatag gtctactaca taaatacttt tcaatataaa
     2641 cacgatggaa cgcggagtgc ggtgaaagtc gcacgctccg tgtgaatggg gggaaaagtt
     2701 tgagatattt ataatatcag gaacttacct atccatatat caatggtttt taaccaatgc
     2761 tcaatcttta gtcttactag cgattgtggt cattggtttg tttttaggat ttaaacggga
     2821 gttttccaaa ctgattggct tcttggtgat tgctttgatt gcggtaggtc tggtctttaa
     2881 tgcttctggt gtgaaggatg tcctactcaa tttgtttaac cgaattgtcg gtgcctgagg
     2941 gggaatcaca atggaacaga tgcgtgttta tattgcgaac cttggaaaat acaatgaagg
     3001 tgagttggtg ggggcatggt ttaccccacc tgtcgatttt gatgaagtga aagaacagat
     3061 tggattaaat gacgaatatg aagagtacgc gattcatgat tatgaactgc cttttgagat
     3121 tgatgagtat acgccaattg aagagattaa tcggttgtgt aacttagcgg aggaactaga
     3181 aggaacgcca attggtgaag ctgcttctga gattcaacac gctttcttca attctttcga
     3241 ggaaatggta gagcatgtgg atgatattgt ctattatcca gattgcgatg atatgagtga
     3301 tgtggcgcat tacttgattg tagaagctgg tgattttggc gaagttccag aacaattgaa
     3361 gccgtatatt gattttgatg cttgcggtcg agatttggag attggaggaa attatttggt
     3421 tactagtcgt ggagtttttg agtatccaga atgaatcaaa cactatatat agtgtttgat
     3481 tagtatatgt aagcaaaaaa acacaatata tagagtgcaa actgaagggt aatgtgatat
     3541 aatatttgcc gaagaaatat ttttgaaatg aggtaatatt atggcaaata ttcaaacaag
     3601 ttttattgat ttccataatt caattagatt ggacgtagaa gacaatacgc tacttaagga
     3661 ctataaagac caagtaattg atggattaaa agattactta cctgatgatg tgaagtttga
     3721 aactttttta cagggaagct attctgttta taccggaata aaaagctgtg atgaaaaaat
     3781 tgattttgac atcgatattg cagttgcttt cgaaattgat catactgttt atgaagatcc
     3841 aagggagcct aaactgtggg taaaagaggc gctagttgaa atttttccta atgctcaagt
     3901 taatttaaaa gtaccttgtg taactgctac atttactgga aaaaagacaa aaaaaaatgt
     3961 gcacgttgat gttgcggttt atgctaaaga agatgaaaat tatttcttag caaaagcaaa
     4021 agaattcagt gctcccgaaa accgatgctg ggaggaagcg gatcccaaag tattaaaaga
     4081 gaaaattaat agtcatgtag cagattcaga tgatcgaaaa caatttcgaa gatgtattcg
     4141 ctatttaaaa agatggaaag ataacaattt taaccaagaa tataaaccaa caggaattgg
     4201 acttacaatt aatgtgatgg atacgttcct agttaataag tccactgatt ttttaactag
     4261 aaaagttcag tataatgata tggaatgtat gaagcagatt gtttcttcgc tgaaagattc
     4321 atttgtgtat gagtacagtg aaacagatgg ttggcattat cgtctacatg catatcttcc
     4381 agtgaagcct aacagtgaca cctattcaaa aatgacagtg aatcagatga gtgattttaa
     4441 aaacaaactt tctaaattat atgatgattt gattttcgct atcgatactg aagatgagta
     4501 tgaagctaca aaacgattaa ataatcaatt tggggaggat tttttaatta tttcagaaga
     4561 agaagttaca gaaaaaaact taagaaatgc atttgttaca gactatccga gtgcttaggt
     4621 tggtgttaaa gattggatta tactgatatt ttaaaagaaa agctaacaga tgttgtgcgt
     4681 ttattcgatg gtaattacta tggggatttt tcatttgcta caattggaaa gttgcgttta
     4741 aaaattgaaa taccaaaaca ttttccattg gtacttccta ggatttacat tcataatttt
     4801 gatcatttag gactttacct accacatgta gaaaaagatg ggttggtatg tttttcttca
     4861 gatataaatt atttagtaga tgaagaaaat tcagaattgg ttttattgca gtgtgttaat
     4921 aaaactataa aaacaattga ggaaggtttg aaagggttaa ataaaaatga ttttcgaaaa
     4981 gagtttgttg ctttttggga caaacaagag aatcaaattt cgttattcta cctttgtgaa
     5041 ccagcgttgt ttatcaagtc agttgataca ataatgtacg gtaagtcttt ggttgctttg
     5101 gataaagaga acgaattaca attaaatgca gcgagtagat tgtttaatgg agagaaagaa
     5161 gatactcatg aattagatgc atactatgtt ccaattagaa acaagaataa tattatgccc
     5221 ccgaagaata ataaagcatg gtcaaagaag gatattttac aaatagtaaa aaaaaatgta
     5281 acaggtgcaa ataaaagatt ttttttaaaa cttgaaaaaa gaaagaatag acataatgtt
     5341 ttacttattc tagatatccc aattgaagaa aagtcaaata atgtcataat tggatttctt
     5401 tttacaaaac aatctggatc tataaaagat tataagggta cgcctaggac tgtattagtt
     5461 cagcgtcatg atgaattata tttggtgaat agaacgagcg gagaaaacta tggattgggt
     5521 gctaatatag ctattgttgg ggtagggtca gttggcagta aaattgctga aaatcttggt
     5581 ccattaggtg tgagaaagat gacactcata gacaatgatt gttttcaagc tgaaaatttg
     5641 tatcgaaatt cacttggtgc agatagttta aaaaatgccc gatctcagaa taattttttt
     5701 aaagttgatt taatgcagga ggagctcgaa aaaaaattcc catacctttg tgttgaagtg
     5761 gagtcaatga acgttttaga cttaattagt atgcaacctg gttttttcaa ggaatatgac
     5821 tatgtttttg tttgcatagg agatacaatg gcaagcctgg ctttaaataa ttatttttcc
     5881 aaaagtagtc aaaaagtttt ctattcttgg ctggagccat atggcattgg gggacacact
     5941 ctatttataa attattctct aaatcaaaaa ggttgtttca attgtcttta tacagattca
     6001 aactctaaaa ataggtgttc aaatagagct tctctggtaa aagaaggaca aatttttgaa
     6061 aggactttag cgagttgccg ctcaaaattt ataccatata atgctattgc ctcgacggaa
     6121 tgtgcaatta atgcaataaa acttttccat aaagtcaatc aaaataatat gaccaatagt
     6181 actctttttt catggatagg agatgggagt acttttgaga atttaggata tcaatatagc
     6241 gacagaaata cttttcttaa tggagtcaat aagtttgaag aaagattctt ttctaaatat
     6301 tgcaaagtat gtggggagtt agatgattaa attttcgtgt gaccgtattg tcattgaagt
     6361 aagggatgaa gttcttaaga tatttgaaca atatcggcag ggaaaggatg acttgcctga
     6421 agctggagga gttcttcatg gaaaaagact taagaatggg agcataataa ttaccgatat
     6481 aacaacacct caaataggag atatacaaaa aagattactc tttaaaaaaa accgagaaat
     6541 tcatcaacag ctttctaatg agaaatggat agaatcaaat aagttttcta ttgcattggg
     6601 agaatggcat actcatcctg aagctgtacc aactccatca aatgttgata agaaaagctg
     6661 gagactgaac gtgagcaagc aacatgatga tagagtttat gtttttatta tcgttggatt
     6721 ttctgatttg agaatgtggt tactgtcaaa aaaatcagat attaggcagg ctataaaact
     6781 ataaaggagt gattaggtga aatcacaaaa gaatatttgg tggtgggggt ttttagtagg
     6841 aaaggtaatg ataccagccc ttctcttaat ttctctaccg atgattactt ttttctttac
     6901 caataaaaaa atgagtaaag aagccgtgat ttttttcttt ggagaccaaa aagctacctt
     6961 tattgaaacg ttagtaacat ctcttcagct taatttgaat tacatttttt caattattat
     7021 tgttatatcg ttattgaatt tttttaaaaa aagaaattca ggaaaggtgt ttaactctaa
     7081 tggaaatgtg tactacaact atttttattt tgtattttgg gtagcagcaa ctttacttgg
     7141 ttatgataaa attcagattg caggaattcc tatacacatg caatataagt tggttttgag
     7201 tggaattttt tctgaggtgt tgccagatat atacgatgat cattacgaca gtgatggaac
     7261 atgtaaagta agcattgaaa aagaaaattt cgatgacatc gatggatatg actctgtgaa
     7321 cttactgatt attgatactt acgatataaa aatgagtgaa ttatctatgg aaaatcaaac
     7381 atatcctacg ataattgtta gagggaattc aatagatgga gttcgtaaag ttaatagatc
     7441 tttaatcttg gaaataaaaa aaacaatgga tgaaattcaa aaaagtgact ttaaaaaagt
     7501 atttgttgct tcaacatcta atccaaaaaa tagtatcaat attattaatt catcgtttag
     7561 atttttcggt cgatcacgta ggtttaaact ttatgttctt caaaaggatt atgcaagcaa
     7621 tggaaagtat agtaagaaat atagaatttt tatttaagaa tgaatttttc cttcttttta
     7681 ttttggagga aactatgaaa aaaataaaaa gctacaccag tatttgggca gttgaaaaag
     7741 tcatttatgc gattaatgac tttcagctgc cttttcctgt gacctttaac cagatggctt
     7801 ggtttgtttt atccttgatg tttgtcattg tatttgccca tgtgcctccg ctatccatga
     7861 tagagggggc ttttttaaaa tacttgggca ttccgatagc ggtcacttgg ttcatgtcgc
     7921 aaaagacctt tgacggtaag aaaccattgg gatttttacg atcctttatc agctatcact
     7981 tacggtttaa ggtcactttt gcaggaaaga aagttaaaga acagaagaaa cgatgggacg
     8041 aaccaatcac cttggtaagg agtgtgaatt atgtacccga ttaagtatat tgaaaataat
     8101 cttgtcttta accaagaagg cgagtgtttt gcttactatg aattagtgcc ttacaattac
     8161 tcctttttgt cacctgaaca gaagtatcaa gtacatgata actttcgcca attaattgcg
     8221 caaaatcgtg aaggtaagat ccatgcctta caaattgcca cagaaagtag tattcgtgcc
     8281 acacaagaac gttcgaaaaa ggaaattacc ggtagactca aagaagtagc aaagcaacga
     8341 attgatttac agacagatgc attagtatcc atgattggcg atagtcagat tgattatcgc
     8401 ttctttattg gctttaaact gatttcgaca gatgaagagg tcaatctaaa gaatctcagg
     8461 aaatctttct tttctggact tcaagaattt gtctatggag tgaatcatca tttgatgggt
     8521 gattttgttt ccttatccaa tgaagaaatt cgtcgctata ccaagcttga aaaactaatg
     8581 gaaagtaaat tggctcgaag atttaaagtc aaacgagtaa cgccgagtga cttgacgtat
     8641 ttaattgaac atatctatgg tgaaaaaggc acaccgtttg aagaatatga attccagcta
     8701 ccaaagaaaa agctgaaatc agaaacgctg gtgaaacgtt acgacttatt acgtcccact
     8761 cgttgtttga ttgaagaaaa gcctcggtac ttacggatgg aacatgaaaa tcatgagtct
     8821 tatgtagcgt acttaacaat taataccatt gtaggggaaa tggagtttcc ttcctcggaa
     8881 cttttctatt accagcaaca acaatttacg tttccgattg atacttcaat gaatgtggaa
     8941 attgtgacga ataaaaaggc cctagctacc gttcgtaata agaaaaagga attaaaagat
     9001 ttagacaacc atgcctatca atctgataat gaaacgaact ccaatgtatt agatgctttg
     9061 gattccgtgg atgaattgga aaccaccttg gatcagtcga aagaatccat gtataaacta
     9121 agctatgtgg ttcgagtgag tgctaaatca gtggatgaat taaaacgccg ctgtgatgaa
     9181 gtgctcgatt tttatgacga taccaatgta aaactagtcc ggccctttgg cgatatgatg
     9241 ggtctacaca aagaattctt accctcaagt aagcgataca tgaatgacta tattcaatat
     9301 gttacgtctg actttttggc gggacttggt tttggggcta ctcaaatgct aggagaatta
     9361 gaaggcattt actttggcta taacgtagat acggggcgca atgtttacct gaaaccggca
     9421 ttggcatcac aaggggtcaa aggctcagta accaatgctt tggcatctgc tttccttggt
     9481 tcgttaggtg gggggaaatc ttttagcaac aatctcttag tctattatgc cgtccttttt
     9541 ggtgggcaag ctgtgattgt cgatccaaaa ggagaaagag gcggttggaa agaaacgttg
     9601 ccagaaattg cggatgaaat taatattctt aacttgacca gtaagccaga aaatcaaggc
     9661 ttacttgatc cctatgtgat tatgaagaaa aagaaagact cagaaagttt ggcgattgat
     9721 atcctgacct ttttaacagg gatttccagt cgggatgggg agaagttccc tgtgttacgc
     9781 aaagccattc gaacggttac ccaaagtgat cagcgaggat tattacaagt aatcgttgaa
     9841 ttgcgtaaag aggactcacc agtcgcggaa aatatcgcgg atcacatcga gtcctttacc
     9901 gattatgatt ttgcccattt gcttttctca gatggttcga ttacccagtc gattagttta
     9961 gataagcagt taaatatcat tcaagtagcg gatttggttt taccagatgc agaaaccact
    10021 tttgaagaat ataccaccat ggaattgctg agtgtttcca tgctaattgt tatttccact
    10081 tttgccttgg actttatcca tagcaaccga gaaattttca agattgtgga cctggatgag
    10141 gcttggagtt ttcttcaagt agctcaagga aaaacgttat cgaataaatt agtgcgtgct
    10201 ggtcgggcca tgaatgccgg tgtttacttc gtcacgcaaa acagtgatga cttgttggat
    10261 gaacgtttga agaataatat tgggctaaag tttgcatttc gcagtaccga tattcatgaa
    10321 atcaagaaaa ccttggaatt ctttggatta gataaagaag atgaaagtaa tcaaaaatgc
    10381 atgcgagatt tggaaaatgg gcaatgcttg atgcaggatt tgtatggtcg agtaggtgtg
    10441 gtccaagttc atccagtctt tgaagaactt ttccatgctt ttgatacccg tccgccagtt
    10501 caagagagaa tggagtgagg agatgaaaaa gaaacttttt cgtatctttg gaattgtttt
    10561 aatcagtttg gtcactctga taatactttt gagcttagtt ggaacggtag ctgaggcaac
    10621 aggtctggtt gatgatacag ttggagccgg aaatctttat tcccaatatt cacttggtaa
    10681 ctatcagttg gatttctttg tggatagttc gtgggattgg ctgccttgga attggggtga
    10741 tggcctaggg aagagcgtaa tgtatggact ttatgccatt actaatttta tttggacagt
    10801 tagtctctac ttatcaaatg ccacgggcta cgtggttcaa gaagcctata agctggattt
    10861 catttcagat acggctgaaa gtattgggaa gaatatccaa accttagccg gcattaccga
    10921 aaatggactc cagacctcgg gcttttactt tgggtttcta ttattgatga ttttagctct
    10981 aggagtttat gtggcgtata caggattatt aaaacgagaa actaccaaag cagtccgggc
    11041 tgtcattaat tttgtgatga tttttctact ttcgggttcg ttcattgcgt atgcgcccac
    11101 ctatatcaca aaaatcaatg attttagctc agatgtcagc gaagcggctc ttagccttgg
    11161 aaccgagatt gtcgtgccga attcagaaag ccaaggaaag gacagtgtgg atttaatccg
    11221 agatagcttg ttttccattc aagtccaaca accgtggtta ctcttgcaat ttgatgattc
    11281 caatatagaa gaagttggcg aagatcgtgt taacaaaatc ctgtctgtaa gtccagatga
    11341 aaataaaggc aaggatcggg aagaagcggt caaagcggag attgaagata atgacaatgc
    11401 gaatctcagt attaccaaga ccatgaaccg cttagggacc gtggtctttt tggtgttgtt
    11461 caatattggc atatccttct ttgtctttct cctaacaggg attatgttgt tctcgcaaat
    11521 tctctttatt atctttgcga tgtttttgcc gattagtttc ttattgtcca tgttgccgac
    11581 ttatgagagt ttgggcaaga aggcgattat tcgcttgttc aatacgatta tgatgcgagc
    11641 aggagttact ttggtgatta cgactgcatt tagcatctcc acgatgtttt tcaatatttc
    11701 ggcaacctat ccatttttca tggttgcttt tctgcaaatt gtgacctttg ccggtatcta
    11761 tttcaaattg ggcgacatta tgaatatgtt caatctccag agtaatgata gccaatcaat
    11821 gggaagacgg gtcatgcgaa aaccgcaaat gttaatgaat cgaacattgc ggcaactcaa
    11881 tcgaaatgtg ggacggactt tggcttttgg tggtggtgca gcagttggaa ataagttggc
    11941 aaaggaacaa tcaaaatcca aatttaagcc atccggttct tctctacgaa agaattcacg
    12001 attaccgaac gatcacgaga taccatctga cttgaataag gaaaagccaa ttccaaataa
    12061 taagaaacaa tcccgaatga atttggccgg gagaaaagtc ggcaaggttc tggataccca
    12121 agctttggtg aaagataaga ccaaacaagt aaaggatgga gtacggaata cgccaaccaa
    12181 cttgaaatac aacttccata aaggaattga aaaaacgaaa aaagcaccgg aagagtttaa
    12241 gcgaggactg gtccaagaaa aagcaaatcg aggagagttg cgagaaaaac aacaacaacg
    12301 tagagacgaa aaaatagctg aaaagcgcaa agtattgaac gaaataggga atcctcatgg
    12361 gaaaagaagg gaaaatgttc cgataaaagc aaaggtccaa tctcaaaagg atagagcacc
    12421 aaagcggatt gtgagagcaa attcgaatcc cgaaatcaaa cgaaaattcg ctagccaaga
    12481 aatcatttca aaaggaataa accaatcctc aagtaagaaa aattcttttc aacaagtgaa
    12541 acggcggtct actctgtcca aacgaaccaa tcgaaaagta caaaaaagtt tgaaccctca
    12601 tcccaaacca aggtcaggtg agaaaaaatg aacgtaaaga aattaagtgc catttcgtta
    12661 actttcctaa caatctcttt tatgggtatc ttgatgtgtg tgggcttatt gtttggtgaa
    12721 gacagtgaag gaagtagtag ttcaggtgct cctcctgggg ggagtagtgt ctcagaagag
    12781 gttttgaaac accgtgcaat ggtggaaaaa tatgccaaag aatcggatat aacagagtat
    12841 gttccgattc ttttagcgat tattcaagtg gaatctggtg gcacaatgga agatgtgatg
    12901 caaagttctg agtcagccgg tttaccaccg aattcattaa gtaccgaggc atccatcaaa
    12961 caaggatgtc tctattttgc gtctttggtt aagcgttcca aagaattagg ttgtgatcaa
    13021 gatagtatca ttcaggccta taactttggc ggtggttatt tggactatgt ggcaaaaaac
    13081 gggaagaagc atagttttgc tttagctgaa tctttttcaa aggaaaaatc ttgcggtcaa
    13141 aaaatcgatt accctaatcc catcgcgaat aaggaaaatg gtggatggcg ctataactat
    13201 ggcaatatgt tttattgctt attggtgaag caatacctaa ctacaacaca gtttgacgat
    13261 aaaacagtcc aagggatttt tgacgaggcg tttaagtatg aaggaacggc ttatgtattt
    13321 ggtgggtcaa gacccgaaac aggatttgat tgtagtggct tgactcaatg gtgttatgcc
    13381 aaagttggtc tgaaacttcc tcgggtggct caagatcagt atgatgccat gacccatatt
    13441 gacctaaaag atgccaaacc aggggatttg gttttctttc attcgactta tgatgccggt
    13501 acttatgtga cccatgtcgg tatttatgca ggggagaatc gcatgtttca tgcaggagat
    13561 ccagtaggct ggacgaatct aacagaaagc tattggcagc agcatcttat cggtgctgga
    13621 cggtacaaat aagagaaaag aggaaaaaga atgaagataa aaattgaacg gaatcaaaag
    13681 gaaaagagcc taaaaaagaa aaaagaacga gtcgtatccg tgggtaagca tcgaaaaatg
    13741 gtgcttgccc tttggctttt attatcttgt agtcttactt ttggcgttta taaaaatttc
    13801 accgccattg atcaacatac aactcatgaa aaagtggtta ttaaagagaa agtagtgaat
    13861 acttctggta ttgaaaactt tacgaaggat ttttcgaaag aatatttttc gtggaaaaat
    13921 aacaaagaag caattgaaaa gagaatgaac aacctcgaac agtaccttac agaagaaggt
    13981 ttcgctttaa gtcaagatat ggttcgagca gatattccca ctaattccga agttcagtca
    14041 gtaaaagtct tagatgttga aaagagctcg gaggaatttg tcgtttcatt tttagtggag
    14101 caaaagatta cagagggaaa aaaggcacaa tcgatttctt ctgcataccg agtgacgatc
    14161 tttgaagatg aaaacaggaa ttatatagta acgagtttgc caactatgat tgcaaaacct
    14221 gatagggcaa aatacaagac aaaacaagta gaaaatgatt cgaaaattga tgccaaaact
    14281 acagaagaaa tcgctgagtt tttggaaacg ttctttaaat tatatccatc agcttctgaa
    14341 aaagaattgg agtattatgt tgaaaatgat gcgatgcgac caatcaatat tgacttaaag
    14401 ttttcgaagt tagaggatcc agtttaccta caaaacggaa aaaaaattct agtgagtaca
    14461 aagataaaat accttgataa tgtatcaaaa accactagct actttcagta caaattaata
    14521 ttacaaaaaa atggaaactg gaaaatcatt gatgttaaat aataatgact caatctaaat
    14581 ttatgagaag ttataagtag tttaacttat ttcaggcaga agtcgcccat cctctatagg
    14641 tgggtgatga atgccgttcg gtaactcgaa aaccgacaat taagacatag tgccttttta
    14701 ttttaatcca tgtcataatc agtctatata agaaatggtt gatataccat ggaattagat
    14761 acaaataatc attcattatt tcttctttgt taccacctta ttttagtagt gaaacattgt
    14821 aaacatctca ttgatgatgt aatgttagct tatgcaaaaa actatctttg aaagaatatc
    14881 agaatcacat cacattacct tagttgagtg aaatcgtgat aaagactact ttcatattat
    14941 gctcaaagca caacctaaaa ccgaattaac aaaattcagc aatgcctaag ctcatgtctg
    15001 ataaaatgag actttctaag ggtcaaaaat ttcctttgaa tacgatcatt agcttagata
    15061 aaagtaaaaa ccttagaact acggggatag cttggttaat aagagatatc gctgttaata
    15121 aagacataag cttgcaagta tgctctattc ccaagaatct cccacttcaa gcactaagga
    15181 tcgttaaatt cagctaagtg gcaagtagtt cactagacga taattatctc catatttcaa
    15241 tctcagcttt tccatttttc atagcaaatt ccgttatttt tatagcatct aaaagattca
    15301 gcttttccac tgatctttca ccacttttca gcttttttat tgtgcttaaa ttgataccag
    15361 taccttttga tattgaattg gaagtaaaat cattaagggt tttttttatt aaattcatat
    15421 ccgcaattcc agcgttcata agaatgaaga ttctcctctc atagactact ttgaaaatgg
    15481 tactacagtg gctgtttata tatttcagta ggttactgta gtggtcattt tattataatt
    15541 agaaaaggaa cctaaatcaa aaatgctaaa gaaaattttc atagtattaa acctatcatg
    15601 actaaagcca cggaattctt gataaaagag tatacttgca agcctatgtc tttactaaca
    15661 gcgatatctc ttattaacca atctatcccc gttgttccta aggttcttga tgttttctaa
    15721 ggcaatgctt gtatacatag cccttgatca aaatattgat actaacgttg acgtttcgat
    15781 catgatgtgt acggcaaata ggacaagtcc attctcgaat tgtgaatgac ttcttaccat
    15841 ctgtgtgtcc acattctgaa ccaatttgac tagacggaaa tcatttatct atcttgatga
    15901 tttttttgac agaagtatcg aaaatcttta cataatctgg gtgttgcatt cttatgcaga
    15961 tgagagcgtt agctccgtat tcataaccag ttgcctctaa aacgtagtcc atcggtggat
    16021 acctagcttg cggttgccag tggctttcgc agtcttcttg taatcaaatc gagcatctaa
    16081 ttgagtacta gtattttgaa gataatactt gagtttttcg gttttcagaa gttcacttca
    16141 tcttccatca tccatggaaa tcccactcac ccatacgcag gcctccaaaa attcttcaac
    16201 aatggttttt cagacatttt tctgaatacc tccttgtttt ttgatacgcc agatagtcag
    16261 gaaaaaggca acaaaacaca aaacaaagct gcctaaaaag gtaatcttca ttccatataa
    16321 aaagacatcc ggccgatctg cgatatagtt agttactcgt tggcccatct tagcagacat
    16381 cgcttgatat aagaccgtcg tagaaagcga aatcccgatg accatcccca aatttcgggc
    16441 aaaggaattc atggagcctg ccagtcccaa attttcgata gtgacagaac tcataaccat
    16501 cgtattattt ggggactgga acaaggcatt gccggcaccc atgatggcag tagcgacaat
    16561 gtacagccac aaaggagagt ccactgacaa aaacatatac atgacttggg ttaccgacaa
    16621 taaacccaag cctactaata caaaaatctc cgggccaacc cggtcggtca ggtatccgct
    16681 taaaggcgcc ccgacgacca tcatcaaggg aaagaccatc atcaacagtc cggcatagct
    16741 aggactcaac ccgcgagcat tttgcagata aaaaggaatc actacattaa caaagaagtt
    16801 ggaagaaaaa atcaacaagg ctgtaatcaa gctcatggta aaaatcttgt tcttaaaaat
    16861 accgaaagaa atcaatggag aggctgcttt cttttcaact tttaaaaagc tgacaaaggc
    16921 aatcactgaa attacgaaca gtacaagggg gactggatgg aaaaagccac tttcttgccc
    16981 caaaaagatt gttccaaaaa ggctgataat cgtagccgca atggcagcaa agccccctcc
    17041 atcgattgta tggccgctca tggtgatatc ttttggtaag aatttttcag caatcaacat
    17101 cgttacgatt cccaccggta cattgatcca aaaaatgtac gcccaagaaa attgggacaa
    17161 aatcaagccg ccaagacctg gtccagcaat cgagcctaat gaaacaagcg caccgattgc
    17221 tcccaatgcc cgaccacgtt catgtatggg aaagacttcc gtgatgattc cggcatttgt
    17281 agccatagtc atactagcac caatggcttg taccacccgt gcgaacaatt aaatacctag
    17341 cgaatgattg aacccacaca acagcgagcc caagacaaag atcagcgtac caatccgaaa
    17401 tactttgatt ttcccacagc tatcgccaat tttaccaaac agcaacaaac aagaacagac
    17461 aatcatcaga taaacggaca ctacccattc cgcttgattc attggtatgc ccatatcatc
    17521 tgagatggta ggtagtgcaa tattgacaat actgccatcc aatgtggaca tgaaggtaaa
    17581 catagatata gcaatcaaaa tccaccagcg atttttttgg acttttgcat cttcttgata
    17641 actatgcata ataggatttc ctttctaatg atcgtgtagc taagaacaat ataacctatg
    17701 tctactgccc aacaacttct cgcgactcta gccataggaa gcttgagtaa tttcgatttg
    17761 ttattctcat gtaaccatgt aagtttgaga tgctttattt gaacttactc tatagtaact
    17821 agtgataatt cgctttactt tcttctagca atttctaaaa gtcgacttca ttgttcttca
    17881 gattaatagt gtgagctatc tcgtgagacg taagaaaatt tccattctac tttttcccaa
    17941 ttttttcata tttatggtgt tgcacctatt tgttttccaa tttgcttttc aaatacattg
    18001 ctatgatatt caattccata ggattatact aaatgtcaat agtatgaata atatattata
    18061 gatgtttata tatcactgtt aattattatc cacaataatt aatgattacc tcgatatttg
    18121 tcaatcaaag gttgaaacaa tttattttca gcatcttttc taacttgagc tgcactctta
    18181 atagaatcat acgatcctaa atagtacctc ttttttttaa agttatatac gcaatccatt
    18241 tctctttaga acgataaact cccttaacac cacttgtatt atttttcggt aattttgacg
    18301 ttagacactc tattactgtc ccttcaacac atgtccttgt ttcttgcctt tttaaacatc
    18361 cacaactttg agtatgtcca aaaaataagt tactataact tatctcacac atactgccac
    18421 actcacattg acaaacccat tttgttttcc atgaacagtt attgtccaaa ggatactttg
    18481 cagtaagtaa tccgaatttt ttattttcaa tgtgatgctt ttttgatttc aaacatccac
    18541 agctttttac atcacctttt agaagtcgct ttgccgatac taactttttt ctcccacaca
    18601 gacattgaca ttcccaaaca acagttcctt cacttcgcag tttagttggc ttgattgcaa
    18661 ctaacttacc aaaagtttta tttgtcaaat ttttatattt atgcctattt ttataatttc
    18721 cacatccaca acttttggtt ctacctgata gtaagtttga tcgatataca atcgtttcat
    18781 tcccacagtc acataggtaa cgatattttt tatatccatt atgagtaatc tcctcaacaa
    18841 cagtaaggtg accatatctt tccttcactg cacctaccct cccaagaaag aagtaccata
    18901 taatttcaat taacttttaa taaatcagaa aaaaatattt tcaatttttc ttagtctgat
    18961 tttatgacta atttataata caagactgaa cgatacgtac acgaaatcct caagatagat
    19021 aaattgtttt catctagtaa aacctgctca aaatatgagc ataaagacgg caataataca
    19081 ctcgatattc gataatggac ttgttttatt tgtcaaactc atcgtaatcg agatatcaat
    19141 tccagtctca atatcctgat caaaggtcta agaatccaac cattttcttg ttactttgtc
    19201 agattgatta ccttttttag tctccgaata ataaggtttt cggatcaact aacatgctct
    19261 gagaaagact actatctttg caaatttcca aatgaaggtg tgggccagta ctattcccag
    19321 tacttcctac atagccaatt atttgtcctt gcaaaacatt atctccagtt tttactaggt
    19381 attgttgctg gtgagcatat aacgcggttg atccatcttc gtgttgtatc accacgtaat
    19441 ttccccaaga gtagtgaaac tctgctttaa caaccttacc agctttaact gcatgaatcg
    19501 gctcaccctg tgtagctgcc atatcaagtc ctcggtgaaa ttcatttcca cgatttccaa
    19561 acaaactggt tattgaataa ttatgaatag gcacttggta tccagtctta ctcatttgtg
    19621 gacctttaac ttctttatca tagttggtta aatcataggt tttaattaat tcatttagct
    19681 tcaaatagta ttgtgtatct gttgcatacc gtcctgtaag gaatttagtt gcttctcgat
    19741 atgttttact attagctttt aatgctcctg cataaaaatc tttatttcca ctaattccct
    19801 tagttaataa tttggcataa tcttcaaaac tttcctcata gttttcatac actctaaatt
    19861 ttgattgggt cgtataaagc gttccattac ccaaatcttc gtttgttacc ataatgacaa
    19921 agtttccatt ataagttcct tttatcccaa ataaattgta attcggtgcc tgagctaact
    19981 ggctttgacc actggcagat tctaagatcg cttgtgcaat cataacagaa gcatataaat
    20041 catatttctg accaattttt ctcgcagact caccaatttt cataataaaa ttttctacag
    20101 attcattttt gtcaaaatga atttcttcat taccagatag tattggttgt gattggaaag
    20161 attctgttga ttctatttgc tgtggtgtcg aaaaattttt tgtttgtcct tccgtttttg
    20221 gcgcttcctt ttttgaagac tctatatggt ttggtcttgt cactttcgaa gaagttattt
    20281 cacttgtact acttgaagtt gttgaagatt cggcacttga aatcgtacta ctttcacttg
    20341 acgaagttgt tgaagactcg gcatttgaag tcgtactact ttcacttgac gaagttgttg
    20401 aagactcggc atttgaagtc gtactacttt cacttgatga agttgttgaa gactcagcat
    20461 ttgaagtcgt actactttca cttgataaag ttgtcaaaag ttcactactc tctgctgtta
    20521 catcggaatt actcatttca gtcgtctcgg ttctttcttt tgcaattttg tatgttgaat
    20581 tttcgcttgc caacacatgg aaaggtgttg ctataaagag ttgggacatt aatataactg
    20641 ctgatgcaag ttttaaagat tttttcattt gatttacctc tcttttttct ctttaatagt
    20701 gttttctatt aaaaattatg ataaatattt tcaatgaatt gagtaataca gtatatttct
    20761 tgatttcatt tagtaacgat tatgtttcaa tgtttaatcc tgttactgcc tttaaaataa
    20821 aattataggg ttggctaaaa ctaggatgaa ataaataatc taacattttc aatttgtcta
    20881 atgtaatttg ttcttctata gcaagagaaa acattgataa tagtcca
//
LOCUS       DACDLM010000051        20664 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.051, whole genome shotgun sequence.
ACCESSION   DACDLM010000051 DACDLM010000000
VERSION     DACDLM010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.051"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            168..362
                     /locus_tag="IV356_001906"
     CDS             168..362
                     /locus_tag="IV356_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015591.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            631..930
                     /locus_tag="IV356_001907"
     CDS             631..930
                     /locus_tag="IV356_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015592.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1027..1461)
                     /locus_tag="IV356_001908"
     CDS             complement(1027..1461)
                     /locus_tag="IV356_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP9015593.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1693..2403)
                     /locus_tag="IV356_001909"
     CDS             complement(1693..2403)
                     /locus_tag="IV356_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAP9015594.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2393..3253)
                     /locus_tag="IV356_001910"
     CDS             complement(2393..3253)
                     /locus_tag="IV356_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HAP9015595.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3258..3896)
                     /locus_tag="IV356_001911"
     CDS             complement(3258..3896)
                     /locus_tag="IV356_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HAP9015596.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3911..4210)
                     /locus_tag="IV356_001912"
     CDS             complement(3911..4210)
                     /locus_tag="IV356_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP9015597.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4253..5737)
                     /locus_tag="IV356_001913"
     CDS             complement(4253..5737)
                     /locus_tag="IV356_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAP9015598.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5757..6218)
                     /locus_tag="IV356_001914"
     CDS             complement(5757..6218)
                     /locus_tag="IV356_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP9015599.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="IV356_001915"
     CDS             complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="IV356_001915"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HAP9015600.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7521..8291
                     /locus_tag="IV356_001916"
     CDS             7521..8291
                     /locus_tag="IV356_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP9015601.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8564..9391)
                     /locus_tag="IV356_001917"
     CDS             complement(8564..9391)
                     /locus_tag="IV356_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP9015602.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9959..11194
                     /locus_tag="IV356_001918"
     CDS             9959..11194
                     /locus_tag="IV356_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HAP9015603.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12193..12453)
                     /locus_tag="IV356_001919"
     CDS             complement(12193..12453)
                     /locus_tag="IV356_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAP9015604.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12480..13781)
                     /locus_tag="IV356_001920"
     CDS             complement(12480..13781)
                     /locus_tag="IV356_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP9015605.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14073..14531)
                     /locus_tag="IV356_001921"
     CDS             complement(14073..14531)
                     /locus_tag="IV356_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAP9015606.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14544..15869)
                     /locus_tag="IV356_001922"
     CDS             complement(14544..15869)
                     /locus_tag="IV356_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005227470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HAP9015607.1"
                     /translation="MKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDEER
                     NMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKIPL
                     KHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVRRK
                     YPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREIMP
                     EIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVVEH
                     TDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLNDDR
                     RRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAVEK
                     LLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15886..17298)
                     /locus_tag="IV356_001923"
     CDS             complement(15886..17298)
                     /locus_tag="IV356_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP9015608.1"
                     /translation="MNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADDMLNIPVIGAA
                     GNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMDPEVNMGIFGG
                     IISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLGFIWPLIQIGI
                     DNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSPSKEVFRGEMT
                     RFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMGSGAGTSFIAN
                     ITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVDYLINFRIATN
                     AILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEETELGLASKNYE
                     YMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISGIIKPTEKNYQ
                     IIIGLEVTYVMAEFNKLLEE"
     gene            complement(17315..18079)
                     /locus_tag="IV356_001924"
     CDS             complement(17315..18079)
                     /locus_tag="IV356_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HAP9015609.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18183..19058)
                     /locus_tag="IV356_001925"
     CDS             complement(18183..19058)
                     /locus_tag="IV356_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP9015610.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(19313..19397)
                     /locus_tag="IV356_001926"
     tRNA            complement(19313..19397)
                     /locus_tag="IV356_001926"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19361..19363),aa:Leu,seq:caa)
     gene            complement(19415..19486)
                     /locus_tag="IV356_001927"
     tRNA            complement(19415..19486)
                     /locus_tag="IV356_001927"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19452..19454),aa:Gln,seq:ttg)
     gene            complement(19496..19568)
                     /locus_tag="IV356_001928"
     tRNA            complement(19496..19568)
                     /locus_tag="IV356_001928"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19533..19535),aa:His,seq:gtg)
     gene            complement(19630..19714)
                     /locus_tag="IV356_001929"
     tRNA            complement(19630..19714)
                     /locus_tag="IV356_001929"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19678..19680),aa:Leu,seq:caa)
     gene            complement(19735..19805)
                     /locus_tag="IV356_001930"
     tRNA            complement(19735..19805)
                     /locus_tag="IV356_001930"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19771..19773),aa:Cys,seq:gca)
     gene            complement(19851..19922)
                     /locus_tag="IV356_001931"
     tRNA            complement(19851..19922)
                     /locus_tag="IV356_001931"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19888..19890),aa:Gln,seq:ttg)
     gene            complement(19934..20006)
                     /locus_tag="IV356_001932"
     tRNA            complement(19934..20006)
                     /locus_tag="IV356_001932"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19971..19973),aa:His,seq:gtg)
     gene            complement(20009..20082)
                     /locus_tag="IV356_001933"
     tRNA            complement(20009..20082)
                     /locus_tag="IV356_001933"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20048..20050),aa:Trp,seq:cca)
     gene            complement(20089..20169)
                     /locus_tag="IV356_001934"
     tRNA            complement(20089..20169)
                     /locus_tag="IV356_001934"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20133..20135),aa:Tyr,seq:gta)
     gene            complement(20171..20246)
                     /locus_tag="IV356_001935"
     tRNA            complement(20171..20246)
                     /locus_tag="IV356_001935"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20211..20213),aa:Phe,seq:gaa)
     gene            complement(20282..20354)
                     /locus_tag="IV356_001936"
     tRNA            complement(20282..20354)
                     /locus_tag="IV356_001936"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20319..20321),aa:Asp,seq:gtc)
     gene            complement(20364..20436)
                     /locus_tag="IV356_001937"
     tRNA            complement(20364..20436)
                     /locus_tag="IV356_001937"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20401..20403),aa:Val,seq:tac)
     gene            complement(20452..20523)
                     /locus_tag="IV356_001938"
     tRNA            complement(20452..20523)
                     /locus_tag="IV356_001938"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20488..20490),aa:Glu,seq:ttc)
     gene            complement(20538..20627)
                     /locus_tag="IV356_001939"
     tRNA            complement(20538..20627)
                     /locus_tag="IV356_001939"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20591..20593),aa:Ser,seq:gga)
BASE COUNT         6531 a         4319 c         3275 g         6539 t
ORIGIN      
        1 taagaacaat agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa
       61 ctttcaaatt gattcttttt atttatcata aagatataga tacataatca ttttcactta
      121 catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag
      181 aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc
      241 ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa
      301 agaacgagct agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt
      361 aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt
      421 atagaattag aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac
      481 catatgatta tttcaatatg tatcctggaa ttggagatct cgtagagcta tatcaagatg
      541 aatcaaatat acttgtcatt catcatgaaa tatagagact tataaaattg tttattttta
      601 taatgtatca gtatagaaag gaaataaaac atggattata ctgttgaatt tgacagtgaa
      661 ctacttaagc aatttccaca agaagaacat ttcatgtata aagaagcaat ttcccacaaa
      721 gtgacagagt atttggagca taattttttt cgtataaagc cagtgcgtac tcgttcggca
      781 aaaggaatat acgagatgaa agtcaaaatt aataaaaaaa attatcgcat agcatttgct
      841 ttaaaaaaaa atcatgtgtt cattttttat attagttcga atttgcaaaa aattgtattt
      901 gataaagagg tgagtaaaaa aataaaatag ctgagcattg gaggatagat tgagtgatac
      961 taagtctatc ctcttgtttt tctaaagaac taagctagaa ttttttcttt tgtacgttat
     1021 tatatgttat ttgtcattac caaaaagcac cttttttctt ctagtatcta tgacataaga
     1081 aataccaccc atttccttta cttgaacaaa tcctactgat tcataaaatt tttttgtttt
     1141 ctcagtatca tctgtcaata attcgatttg gactggtcca taactagtga tcttctccaa
     1201 agcttcattc aaaagcactt tgcctattcc ttggcgctga tacctcggat gaatgaggat
     1261 atcttgaata aatgcgatcg tcgcaaaatc agtgatccaa cgaacgattc cgataatctt
     1321 cccttcccca ttacgcttta tcagagattc agattgttca aatgctctag ctaaccttgc
     1381 agtgtctttt gtgtaattcg tccaaccaac gctcttatat aattcagaaa tctcatcgat
     1441 cataagggaa tcaatattca tttttttctt cctttcttat acaattctcc ctctaataat
     1501 acagttcttt gactatttaa tctatcacat ataactctcc tgtaaagatt ctctcgattc
     1561 cttaaaattc ctctttcctt ttagaatgca tactttttga taaataaaaa ggttgtgata
     1621 aattttcttc acaacctctg tttctctcta tcaagtgtta tcttttaatt ttctaccctt
     1681 accctagcat ctctattgcc cgtagtatgc atactttcca tgtttgcgaa aataatgttt
     1741 atctagtaaa tattgcggga tttcacatat attggggttg atcagctcgt tttctttggc
     1801 catcagacaa atttcatcta agatcaaact gttttctact gctttcatag gtgaatcccc
     1861 ccatgtgaac ggtccatgtc catagacaag tactccaggg acttcgtttg gatctaattt
     1921 tctttcctta aacgtctcga caatcacatt ccctgtatga acttcgtaag cttctcttac
     1981 ttcttctttc gttaattggc gtgtacaagg aaccttacca taaaaagcat cagcatgagt
     2041 cgtgccataa gctggcaaat cgcgtcctgc ttgcgcccac atgacggagt gcgtggaatg
     2101 agtatgagta atagcagtta tatcttcaaa agtttgatac aaaacaacat gtgtggggag
     2161 atctgaagat ggttttaagc tatcttcttc tattatattt cccgacaaat ctgttaccac
     2221 catttgatct gcttgcatgc attcatatct gacaccgctt ggcttaatga cgatgactcc
     2281 tagctcacgg tccacttcac tcacattgcc ccaagtcaat ttgactaatc cgtatcgcgg
     2341 caatgccaga tttgcttcaa ggacacgttg cttcattgct gcaatttttt cttcacaaga
     2401 catcatagcc agcctccttc aatttagaac ttaagtagtc ttttgcctgc tggatttctc
     2461 ttcgaaagtc ttggcttttt tcactccaca tttcaatcag aaatgttcca tcataatcta
     2521 gacgtttcaa atgtcttaat aatccaagaa aatcaacaca accgctacca aaaggaacat
     2581 cacgaaactg gcctgaatat tcttttgtta cagggtaagt atcttttaag tggatagcag
     2641 tgatataatc gatccctttc tcaagttctc gagccggatt attttccggc catgcggaca
     2701 aattgcctag gtctggatat acttgtagaa aaggtgaatg aatctgttct ttgatttcta
     2761 aaaattttga aatggagttc ataaatggat catccatgat ttccacggaa agaatgatgc
     2821 catatttaga agcttccttt acgctttctt ttattccttc gataaagtct tctctggaat
     2881 tcattgattt ctcttcataa taaacatcgt atccagctat ttggattact ttgacgctta
     2941 gattatgcgc caaatggatt gcttttttca ttagttgttt cgctgctttt ttcttttctg
     3001 gatcagcaga accaaacgga aatcgccgat gcgcacttaa acaaatcgaa tggatacgta
     3061 caccggagct gaacatctct tctctcagct cagctatctt ttcttcagac caatctaatc
     3121 gtgctaaccg ctcatccgtc tcatcaatcg acatctcgat aaaatcgaag tccatttctt
     3181 ttacaaggga aaaacgttct ttccatgaaa tatctttggg taacgctttt tcataaatcc
     3241 caatttgagc catttcctta cccccagata cgaatgatct catctttgaa gttttgtgcg
     3301 gccttcatcg gatcatttgc tgctgtaata ccacgaccag tgataaaggt atacacatcg
     3361 atcccttcaa ataagtgtaa tgtgtgtgga tttaatccac cagttacaga aacattaaag
     3421 cctagttcaa tcagtttttt gatcttcgat aaatcttttt caccccaagt ttcaccagat
     3481 aacagcgcat cacggctttg atggtagatt acctgccgga taccgatgtt atgccaatcc
     3541 atggcttgtt caaaagtcca attgccgtag agttctactt gcaattcacc tatttctttt
     3601 tgtgctgcct ccatagttgg aatcgttgca caacaaatga ctgtcatcca gtctgctcct
     3661 gcttttgcaa cattactcgc cactgttcct ccagcgtctg cacatttcgt atcagcgact
     3721 agttttttat ctgggaacat actgcgaata cagcgaatcg ctttttgtcc ttcctgtaag
     3781 caaagaattg tgcccacttc aataatatct actacatcac caactttcat aacatctcct
     3841 aatgcatgtt ctaagtcatt gtgatctaac gcaatttgca aattcggcct gctcatctta
     3901 gttccttcct ttacttgttt ttttggtacc actttgtttc agcaaatttt tcactgattt
     3961 ctttgactga catcacattt ttgataccga taactgtaac tccttttttc tctgcctgag
     4021 taaacatatt caaaaaattg actggcgtaa aaactacatc gtattggcca gctgaacttt
     4081 ttccctctga aatggcacaa tgatggattt tggtaattgg tacgtttagt tctttcattg
     4141 ctttttccac acttctcatc atcatcaagc ttgttcctga tccatttgca cacgatacta
     4201 aaattctcat cttaatccct ccattatgag tgttgtctaa tcagattttc ttttatactc
     4261 tctgcttttc tgcatatgtg tcatagtctt ctacaatcaa aaaataacca tcaggatttt
     4321 tccgatattg taactgcgga atagccaata aaccaatgac aactacggca attccagcat
     4381 aacctaggac tttcatgatt actgtaaaca atggccaagc tgttgcccag tcgaacatcc
     4441 cgatataacc accgtatgtt gacatcccaa tccatgtagc gaataatgct gaaccgccta
     4501 cttgtatgat tcctgaaaga aacgggaaca ggcaagcggc tttgaatcca cctcggttat
     4561 tggcataaac tgctataacg gcattatcaa agaacaacgg aatgaaaccg gctatgacga
     4621 tcgttggtga tttcaataaa atcagtaaac caatcatcaa aaactgtccc aaagcaccaa
     4681 acaagaaccc aatcgttacc gcatttggcg aaccaaagcc aaaagtagca gctacgtcaa
     4741 ttcctggaac agctcctggt aaaatcgtgt ttgagattcc ttggaaagat tgagttagtt
     4801 catcgacgaa tgtccgaaca cctaattgca agatcgccag atataccgca aaatttaaag
     4861 aagtcgtcat aatgtagaat aagaaactct gcccttcttg catgaattgc gcttgaatca
     4921 aataatcttt gcctagtaca atcagaatga tcccaaagaa aaatagcatg agtaacgaag
     4981 tagcaaccat attctcattg aaaatcgaca agaatcctgg taatttgata tcttcaattt
     5041 ttttgtcttg cttgattgat ctatttttct tttcatcccg ctttttcatc cactcagcta
     5101 attttgcaaa tataaagatt ccgaacattt gctgatgtgc cactgcaaat ccggcacctt
     5161 ctgtcaattc ctgcgtgatt cctactgtta agttagaagc tactgtccaa taacaaccta
     5221 aaatcagtcc cataaaaatc aatgcttgta tcctacctag atcaggaaag caaaacagta
     5281 aaatccaaaa agcggtagct gcttgttgaa cctgaacgtt tccggtagtg aaaacggaac
     5341 gcagtttcgt atatttctga aaacggacta ataagatatt taaaacaaat gcaatcagta
     5401 ataaaatcat cacatctcca aaggtacggc caaatgtctc cattaatcca gcatccacag
     5461 cattttgtcc aaaataagga tctgtaacca tggcatccaa attgaaccgt tcctttagtc
     5521 caaccaagat tggccgaaaa ttattgacca aaccaccaga gccaacagtc aaaataaagt
     5581 aaccgaccgt tgcctttaag aatccagcga tgcattcatg aagcgggcgt ttcagcaaaa
     5641 tatagcctaa taacacgata aaaccaatca ggtatgctgg ctgcgtcaag atatttgttg
     5701 caaaatacgt ccaaatgctt aacaaaaatt cccccatctt ttttctcctc tatcaattaa
     5761 ttatattctg ccatcacaac ttggtaatca tcgatggagt tcgtagagat gagacgctca
     5821 accaatccat ctgtcattaa taattcggat aatttttgga tattttctag atgttcttct
     5881 ggatcttttg ctgcgagtgt aaaaaacaaa ctagccgttt tctcctcatt ctccccttca
     5941 ctttcaaaac ggattggctg tttcaacttg gtaaatgaaa tagctgttcc aaaaacacca
     6001 tcactttttt ctgaagaatg cggcattgct acttgaggtg cgatcacaat ataaggaccg
     6061 tatttttcta cacaatggat gatctcctcc acatacgttt catcaataat ttccttatcg
     6121 atcaatacaa gacagctttc ggcgatagct tcacgccaat ccgtgatttc tttatctggg
     6181 taatgaatca attgatggtc aaaaaagtat ttcagcaaga aactcccctt ctttcttata
     6241 aaaacgacgg aaacggtgta tcattttcaa tcgagaagac atcttcaaat cctcgataaa
     6301 aattaaactc aagatcatct ttgtttgtcg gatagatgaa tttcccgcct acttgccaga
     6361 tataaggttt aaatccatac ttcaggcgat cctttttgaa tttccaaatt tcagtgatct
     6421 cttttggatc agccataaaa ttagaccaaa tatcgtagtg gacaggaatc actacttttg
     6481 cattcaatga ctccgccatg cgcagcatat caacagaagt aactttgtct gttatccctc
     6541 gtgggttttc accataggcc cctaaacaga catcgatttt gtgttcatta ccatgtttgg
     6601 caaataaatt ggagtaatgt gaatctcctg catgataaag attccctcct gatgtttcga
     6661 ataaatagtt tactgcaatt tgatccatct cctgaggcat ttttcctttt aatacctctt
     6721 ctggatcttc acaagtgacc aacgctgtcc gatcaaacgc ttctaaagct actacattga
     6781 tgtctttgat tttgactgca tcacctggct ttactgtaat cgttttttct tcaggaattc
     6841 cccatttttg ccacgtgcga accacttctt ttggcccaat gaatgttgct tcaggacaat
     6901 tttgatgaac tgctgcggct gtatggatat ctagatgatc ggaatggata tgtgtaacga
     6961 ttaaagcgtc tacatttttt atcgcaaaag gatcgattac gaaaggctga gtacgtaaat
     7021 taggctgcat attttgaacg ccactcatac gcatcatctg atggcctttt ttcatcatgc
     7081 cattcccatg actacgtttt cccgtcccac accatagatc acataaaata ttcgttcctt
     7141 catgactttt cagccaaatt cccgtacagc ccagccacca catagcaaaa gttccaggat
     7201 ccactacttc tgtttcgatt tcttcattca agtatgtgcc ccactcagga aatgtttcta
     7261 ctaaccactt ttcttttgtt acttcattga cagttttact catttgcttg ctccccccat
     7321 atcgttgttc caacttacaa gtaaatatta atgtgtatca gcatccatga aaaccctttt
     7381 atatgaccgt ttgtttttta tatgattttc tttcagtaat caatgattgt ttcagtataa
     7441 taaagacaga tatgaatgtt taaatgaaca actagtcaaa taaatccatg gatcaagatg
     7501 tccctcagga ggcaaaagtc atgaaaaact cacttgtcaa tattgaaaaa cgtcaaaaag
     7561 aaattttgga actgcttcag cagactgaac aactatcaac tttcgaatta gctgaatccc
     7621 ttgatgtatc tattagtacg atacgaagag atttaaattt attagaagaa aaaaacgaga
     7681 tcatacgcaa ttacggttat tgttcttata attacaaaaa ccagactgat tttgatcaat
     7741 ctggtcctga aaggattaaa caagcgattg ccagagaagc tagtaaatac attaacgatt
     7801 atgatacgct gtttatcaat tctagctcga ctgcgttgaa aacactggat tttcttcaat
     7861 ctaaccattt gacagtcatt acaaacaacg tgaaaatcaa ttactctccg cacaaagata
     7921 attgtagtta tattttaact ggtggagaga tgcgctttcc aaaagaagca ctagtgggcg
     7981 acatcgcatt aaatacgatt tcttcagtca atgcagacat ttgtatcatt ggctgtagcg
     8041 gagtcgatgt agtacatggg gtcacaacaa agatattaaa tgaatcaacg atcaacgaaa
     8101 tgatggtcaa caagacaatc aaatgtaaga ttttagtcgc tgatcatcga aaaatcggac
     8161 tgacatcaaa gttcaagatt gctgatattt cagtctttga ttatttgatc actgataaat
     8221 tttgttctga aaaagtatta gaggagatca gaaatacggg gataaaaacc attcaagtag
     8281 attcatttta agaaccagga cgtaaatatg taaataggat tatcaaaaaa atgaataaca
     8341 aatttatcga taaatgaaaa acacgctacg ctcaaattga taaaggaatc ccaagatgta
     8401 tccatccaat cgataccatc ataatctatt gcttctttta taaccgttat atgttgccta
     8461 aataggaatc aaacaatatc gaaaaaagga ggtatgacaa aagtcacacc tccttttttc
     8521 gaataaacgg tattcaaatc agaacactga tttcacaacc actttatttc aggtcgtttt
     8581 caatcacctt taccgcgtaa tcatttccgt tgaaacgcgc tatttttttt gcgtccatat
     8641 atctttctaa ataatcatct tctcctaatt gcttatggca agaagcaatt tcataaagca
     8701 agtattccaa tgcataagtc gatttatgtt tcttattata ctcaataccc ttctcacata
     8761 attggattgc tttatcataa tcctcgattt tacggtaata ggtggcgata tcataatata
     8821 caatgcagac catcagatta tcaaaatcag tctcactcaa tattttaagt gtacgctcca
     8881 cataaacttt cgcaaaatct aattctcctt ttgacaagta gatcattgcc acgtttgcag
     8941 ctgcttgtaa gtgatggata tctgtttcgg tcgtttgttc caacacttga ttaaaataaa
     9001 ataatgctgc atctggtttt ttcgcataaa gatgatcaag cagtccttga taaaataaaa
     9061 tttgatttaa aagatcagaa ttacttactt tttcctgatc gatcgtttgt aaaattttat
     9121 aagattcttg gtattttgat acagaattca atgattgaat ctcatttatt tttttcctga
     9181 ttttgtcttc ttctgtttct actaatatat cggagatctc gacattcagc tttttgcaaa
     9241 gcgcacttaa gatattgatg cctggcgaca tattcttgtt ttcgatattg ctgacagttg
     9301 cttgttcaca aatgccttct gctaattgta cttgtgttaa cccctttttc tttcggtatt
     9361 cttttagtaa tgctccatct actttaatca aaacaatttc cttcccttta aaaaattatt
     9421 tctcctttat atcatacaca aaaaaaagtt ctaaacaacc aaaaatgttt agaacagaat
     9481 aaaaatttta attttaaaat aatattcaaa ttaaacaact ggcgtatctg ctccttgatt
     9541 tctttttgtg ttatctgaat aattatcgtt tacagttata acacatagtg aaaattgtca
     9601 tggcgagaaa gtctaagaat atttttaaac ataactattt ctttcttacg tgtgtataat
     9661 gacgacagca cacctatcaa ttaatataat tattttattt ttttatgttc tcatgtttat
     9721 ttttaatgac acaacttctc gtatttatct ggcacaacat ataaatcgat caaaaaattg
     9781 ttgcgtgttt ttttgaaaat tggagtttca acttgattac aaaatttaaa tttagaagtt
     9841 gtgaaaacag cgagagacag tttaatattc aaaatataca taggctactc gaacgctgtg
     9901 ttttttagta tactagtaag aaacgaaggg atagactcat tccaataagg aggatttcat
     9961 gaagacaatt ctttttgctc ctgcagtatt caatttagct gagacaacac gaatgattga
    10021 ggttgccaaa gctatgaaag accgttatta ctgtgtattc tttggctttt ctaaaacttt
    10081 tgctcctttg atcacagaaa gtggctttga gtatcattta ctagcgccga tccttacgaa
    10141 aaaacaagaa gaacaaatca taaaatttga ccagttgcgt acacttaaaa acccttttac
    10201 caaagaaatg gttgcctctc gtatcactag tgaacagagt ctgattgcta agtttgagcc
    10261 tcgactgatt gtgacaggtt cgaatgtgac aattttttta tcggcccgca ataaaaagat
    10321 tcctttagta tatgttaaac cctatgcttt gagtgaacct ttttttcaat cagagcatgc
    10381 gctgatgccc cacgagttac gtttcttcgg ccctttaagc aatccccttt ggcactggac
    10441 aaaaaagcgt atagtaaata cccgatggat ccccaatgcc ttcaaacacg ctgcacaaaa
    10501 agaaatgctt cctttaccaa aaacaagttt acaaatgatg gatgctgatc taaatctcat
    10561 cacaacgcct aaactatttt tggaagaaga acagctgccg gaaaattatc gaatcgttgg
    10621 tccaattttt gctaagctca gtacttcctt gcctgaagaa gtgctaactt ttatacagcg
    10681 aaagcaacaa gaaagaaaac gtattatcta tttcgcaatg ggtagttcag gcaatccgcg
    10741 tatgttacgc aaaattttgt tcttcttaca aaaacaaccg gatctagcgg ttattgcacc
    10801 tattgactat ctgcttgatg acattcaatc tgactcagaa gatcttttaa taacagaata
    10861 tctgtctagt catcttttgc atgaattcat tgatttttct tttatccacg gcggggaagg
    10921 gaccgtccaa actgcctgtg aatccggcaa accgtttatc ggtgtgggga tgcaatttga
    10981 gcaaagctgt aatattgact attgtgtaaa atacggaaac gcaatcgccc tcacaaaacc
    11041 agtgactgaa agaaaactgc agattgctct gcgcgaagtt tcttcaccca agattcgtca
    11101 gcaggcacgc acgctgcaag ccgtttttcc aataaatggt ccacaacaag caattcaaga
    11161 aatcgaaacc ttcctgagca accacccaat atagtttcaa gtagaaaaag cttttttaat
    11221 agagactcat cagtaatttc gctattcgag acccagacag tgaaaataca aaaaaagtaa
    11281 atagtggatt gaaaagttag agttacttaa attacggtgt ctaaaaaaca caaaatcatc
    11341 cttaaaataa aagatctgac gctatccaaa tgagcatagg tagcgtctgc catttattct
    11401 tagtcaaatt ctttgacacc tttctctggt tggatcatct caacgtttct tcaaaagaaa
    11461 gaccataata attaggcaaa tacattttct taaaatgtgt catatagatc tagaagcatc
    11521 gctttgtaga gatttgtgcc gctagtcccc tcaacaatta ctaaatcaaa tgtaggattt
    11581 accactttat ctttgataat caacctccct cttctgttga gacaatgatc tcgcaatccg
    11641 atgcatactc ctatataaac tgccagcaat ccccacatat tgagtagatc atgtcagaat
    11701 gttctatgtc gtcagcaacg atacactaaa agtcacgttc accatgactg attgctattc
    11761 ccagcacaat tatttctata cacgtttcat gatttgaata aacactcaca tcatacatat
    11821 taccattcat acaccatact gcagccccta ctatatggtt gtaagctccc aaatctatat
    11881 ttgacttgat cactttggta gtagatctac taattctaaa tccattgctg ataaaatttc
    11941 cattttttcc tccttctttc tgccaaaaca gttaaaacaa taataatctt tatgtaaaaa
    12001 agggctgtga caaaagcctt gtcacagtcc catattccga ataaacggtg gtcaaaagct
    12061 tgcatctgcg gtaataagtt caaccaaacg aaaaataagc caacatttca caaaaattta
    12121 agaagcaatt ttcgtaaatt tcttcttatt tcttgaagct aaccacttct gttacaacca
    12181 cttttagaac atttaaagct tcgatgtgac aaaccatcta tgctgctcga tcataaaatt
    12241 gatagcaaaa attccacaaa gtacatatgt cccccatgaa aacaaaacat tcatatgcgg
    12301 tacaatgatc tttggaagaa tcacgatcaa aaatgatgcc agtgcccaaa tccatcgatt
    12361 gatttgaata tgatatgtag ctagcatatt caatataagg tgactagccg ttaataaaaa
    12421 gataaaaaca aaaaataaaa tcagccaata cattgtttcc caccttctaa aaaccaaact
    12481 tagacagtct ggacttcgtt ttctccacga ctttgttcat ctgacagcat ctttttatca
    12541 taagctttta caaatggata atagataata aatgctatca atgtgttgat catgatcaag
    12601 ataacaacac gccagtcatt tcctgctgaa agataaccgc cgattggagc tggtaatgtc
    12661 catgttggca aaacagtaaa tctattgacc atttctaatt tgactgcaaa ataactgata
    12721 atagtcaaaa ctaaaggaac taagttgaac gggatgaaca tgtaaggatt caacatcata
    12781 ggagctccaa aaattatggg ctcattgata ttgaagatac caggaataat agaaaaacga
    12841 ccaacctctt tcaagaattt tgatttacag aagaatataa acaaaacaga taccacgatc
    12901 gttgctcctg caccaccaat tgttaccgtc cattgataaa actgttcagg agcgatatag
    12961 ggtaattggg tggcagctgt accatctgcc aatgcctttg cattctcatc caacatgatc
    13021 agccacattg gacgaacaac agcccctaca atactcatgc catggatacc aaatgaccac
    13081 aacaaatgga tcaaaaacat tggtagtaaa acaccaagca aattattccc taaaatattg
    13141 gttaaaggct cgaataacga taataaggca gcgtttacat caaagcccgc gacgcttcga
    13201 atcagccaag taattgttaa aatgactgca cctggaatca atgcctcaaa actacgggca
    13261 acagcaggtg gcacttgttc tggcattttg atagtaatat ttcgattttt aaagaaacga
    13321 tatacttcca ctgcaaaaat catagataag atccccgcaa acatcccaga tgctcccaaa
    13381 gaactcatag gtaagaccca gccaagaggt gcctcttcag gagttaaaac gtttacagga
    13441 acttgtaaca taaagaacgt tcctaaagat aatataccac ctgtcacact atctaatcca
    13501 tatgatttag ctagatccga acccataaca aaagttgcat aaatagccat caatcccatc
    13561 gtcatcctaa agggtaaaac aatcgttgcc gaataagggg caataaattc attccatcca
    13621 ggaaacggta aattgataaa gaccataaaa aatgtcccaa tcaaaatcaa tgacaatgtt
    13681 gaaacaaccc cattacgaat tgctaataaa tgacgctgtg taccaatttt tgccattggt
    13741 gggacaagtt tctcttcgac ccatttcatc agcttttcca ctaaaaccac tccttttcaa
    13801 taaaatatga accattcatt gcatgacaac gcaaagaatg ttcataacta attatataat
    13861 taagaaattt tatttcaata tattctctta aataatcaaa tttattttta agaatcctga
    13921 aaataagttt tctaaatcat aggagcaaca aaaaaattcg ataattaaca aaaatcaaaa
    13981 tgattaaatc tagtgattga aacatatcat ttcaaaaaaa ttttgtaaat tcacccataa
    14041 atatcaccct atttaacttt tttcatcgta cactaaaatt caaaacaact atctttaatc
    14101 tttacttctt ggttttgttt taataaattt ccttcaaaaa tgcctggaga aactacaatg
    14161 atcaccgtat ctttttgtgc ttgctccaac ttcttcaaat ctataatagc taacagtgtc
    14221 ccttctttta cctcctggtt actttcaacc cgtatctgaa acggacttcc ttcgagttca
    14281 actgtatcta aacccatatg gatcagtatt tttctgccag attcactttc gatcgttatg
    14341 gcatgtcggg taggaaatat attatcgatt attcctttaa ctggcgcatg gatatatcca
    14401 tcatgattcg ttatagcgta tccaactcct atcatttttg aagaaaagac ctcgtctttt
    14461 actgctgtta atggaataat ttgaccacta gctacagctt ttagaatgtt tcttgtttta
    14521 aagaaatgca ctttttatca cctctacttt aatgctggcc aatatttttt gtttactttg
    14581 atcatttcat ctagtatttt ttttgcgact ctggcatttg gtacggtttg attcaatgta
    14641 aatgcttgta aagctttttg ataagaacct tcaaagtaag catctactag taacttctct
    14701 actgcaactt gtgcctccat caatccttta tgaaaatcac tgattggttt tcttagtgta
    14761 attggctcca caccagttgc accaacatat gccggtattt caacaactgc atctgaccgt
    14821 agattcggaa tcgccccttg attaggaacg attagcataa agcgacgacg atcatcattc
    14881 aacaaggaaa tagctatatc gacgatatat tgtccatgct ccccaaaatt aaagttcaat
    14941 acttcttcca caataccgcg gcgtatttta tcagccattt ctttggtatt tttctctcgt
    15001 ccatccatga ccatattagc acgtgtatac tctttgtcag tatgctcaac gaccatatca
    15061 ggatataagt aatactctaa gtaattattc gggatattac ttggaaaatt tttcgtgatg
    15121 actgacatca tttgaaaggt tttttgccaa gttttatctc ctatattaaa atcggcgact
    15181 tgcatttctt ttgttattag tttttcaata atctctggca taatttctcg ttgcaattct
    15241 ttatcataaa tcgatgtata ccagccaaag tggtttaaac cataatacgt aacgatccaa
    15301 ttcttacgat cataaccgta attcactgca atcgtttctt caattgaaat agtcatatca
    15361 caggcattaa tcatttttac attcggatat ttacgacgaa cagcttcaga aacgatcgac
    15421 tctggatttg tataattcaa aatccatgct ttgggggcat agtcttgtat atgatcgaca
    15481 atttccaata aacctttgat tgagcgcatc ccataagcaa atcctccgag tccacacgtt
    15541 tcttgtccta ctaatccatg tttaagtgga atcttttcgt ccttttctcg catctccaat
    15601 cctccaacac gaatttgtga gaaaacaaaa tcgcatcctg taaaagcaag ctttggatca
    15661 tccgttgcac gaatgcgaat atttgaaaaa ccttttcttt tcagcataaa tttaacaatc
    15721 aagtacatat ccatatttct ttcttcatca atatcatata aacgtatttc agataatggc
    15781 aaccgttttt cattgttcaa aatggcttga acgattcctg gtgtatacgt actcccgcct
    15841 ccagctatag tgataatctg ttttttcatc atcatctttt cctttctatt cttctaataa
    15901 tttattgaat tctgccataa cataagtcac ttctaagccg atgataattt gataattttt
    15961 ttcagttggt ttaatgatcc cgcttatccc taattgcttg attcgctgtt cctcgaccat
    16021 ggtgggatcc actacctcta cccgtaggcg tgtattacaa ctatagacat ccaggatatt
    16081 ggcttttcct ccaaacgctt gtagcatttt tgttgccata tattcataat ttttacttgc
    16141 taaccctaac tctgtttctt ctaaggttac ttcattgcca aactctgcct tagcttcacg
    16201 tcctaatgtc tgaatgtttc tcttattgat caaataataa aaagtaacgt aatacaaggc
    16261 aaaaaagaaa attccgattg gaagaatcaa aatagcattg gtagcgattc gaaaattgat
    16321 gagataatca acaatacatg ctccgaatgt aaaaccaatt cgtatattga ataagtaaca
    16381 gacaatccct gctaaaccgg caaaaagtgc atggatcacg tacaacatag gagaaagaaa
    16441 catgaaacta aattcaacag gctcagtgat atttgcaata aatgaagttc ctgcaccgct
    16501 tcccatgatt cctttgacca tctctttatt ttctttataa gctgctttat agatagctag
    16561 acatatagct ggtataccaa acatcattac tacaaaaaaa actgataaaa acagtccagc
    16621 ctgaggatct ccgttgataa agcgtgtcat ctctcctctg aaaacttcct tgctaggaga
    16681 tgtatagctt cctaaatcgt aataaatata cgtattcaac acatggtgca gtccaaaggg
    16741 gatcagcaaa cgattcaaaa acataaatat ccccacacct aatgctccca tatcaacgag
    16801 cagttttgca aaattatcaa tcccaatttg gatgagcggc cagataaagc ccaaaaaaac
    16861 agctgcgatt gtttgtagaa tcatcaccat agtcaatggg aatttttcgc ccgcaaaata
    16921 agaaaaaact actggtaatt tttgttcttt aaagcgatta tacgtccatg ccgctactaa
    16981 accggaaata attccaccaa aaatccccat attcacttct gggtccataa tttctaagcc
    17041 ttttttcaag gtagcaatcg ctaaaaaacc agtaagtgca ggtattcctt tgtccttatt
    17101 tttgacaaaa ccgattgcaa ctcctatagc aaataagata tccaagtttc caaaaacggc
    17161 atttccagct gcaccaatta ctgggatgtt cagcatatcg tcagctgata aacgcatgat
    17221 caatcccgct aatggcatcg ctgcaactgg aagtagcatc gctcttccaa gcttctgcac
    17281 atttgattta acattcattt ttattcctcc tctattaaat atcctcatat gttactaact
    17341 caatcaaagg atcatttttc actttttgag caaatgctga atgaattaaa aattcgactt
    17401 ggtgggtacg aggatacaca aaacttgaac catttaacaa ttcctgatcc aaatacgctg
    17461 cgtgacacat gacttcgatc gttttatctt ctctcaatat catgagtaaa cttgccaaat
    17521 attcttccac actcgtattg atttgtcgtt ttttttcatc agtttctcct acgacatcga
    17581 aacaaggctc aaaataatcg acatgacgaa cttcatcttt tcgttcaaag ttgctccgaa
    17641 ccggcaaatc atattttttt gctaatgtaa caactacctc ctgattttca tccaaagtat
    17701 gagtatgatg atgactgtct aaatgagttg gtatgatccc cgcatgataa attttttgaa
    17761 tctgagcatt ccattcctga tacagttgat ctttgtcaat gttaaatgga tgctgataat
    17821 aagataagga tctgaactct ccgctttcga taagagtatc gacagttttg aggagtggtt
    17881 tgccacacgt caatgttaaa tggactccta cacctagcct aggcatttcc tttcttagtt
    17941 tcacagcatg ctcgaaaccc ggcatatttg ccatcaatgt agttgatgtc aaaattcctc
    18001 gctgataagc atccataatc ccataattca caccatggct atagccaaaa tcatccgaat
    18061 taaaaatcac ttttcccatt tcattctcct tcttttttct actaaaatag gcgcaaccaa
    18121 ataatcatag tccatttact atgtgtcatt tggttgcgcc tatagatagt tacgccctta
    18181 ttttaataga ttcttgctag atgaattgcc aaatagatga tttcattttc ttgaatggca
    18241 agttgaaatt gctgttcgat gatatcttta atctttagtg ctgtacaata cgctttgcta
    18301 tgtttaaatg tttcagtaaa aaaaccaata ttttctactg gcgtttcttc ctgataaatc
    18361 aagcgtttaa ccaggaattt gatatgaacc attaagcgat gataagtcag tgattcttta
    18421 tcataaacgt ttgaatagga tttttctaga tgggacaaaa tcgtggtcgt catttctact
    18481 atttttaagc tctttaaact attaggctct cctagctcag cattaatgat atgcatagtg
    18541 atgaatccta cttcatttga ccctaactcg gtttgatatc gatgattgat tcgctcgacc
    18601 acttctactg ctatatcata ttcatttgga taaaggaatc tcatttctgg caacataatt
    18661 gctgtgacat ctctatcttc tctttttcgt tgaatagcaa aataaatatg atctgtcaat
    18721 gtaatataga tatttgaatc taatggagag gagatcctag ctgttatcag ttcaatcact
    18781 tcttccgcaa aatccataaa ttcgattgga atctgcgaga ctatctcact gaatcgtttg
    18841 atcttttctt tagaatctaa tacaaataat ttgtcagcat cctcaacatc aaatggctta
    18901 ctcactttag cagaaaagcc aatccctttc cccatcgcaa ttttttctat tccatcgtca
    18961 tcgatcaata cagcattatg attcagcttt ttcatcacat acaccgttaa ttcacctcct
    19021 ctatatgata aaacaaaaca acttgcagac tccttcatac atatttttgt ctccaaacaa
    19081 tttttaaaga caaaaaacga cctaagaaag aaccctttct taggtcgtgc ctaattgaat
    19141 agtagcaccc tacataattt acaaaaatag tttaacacat aataaaagcg ttatcaatat
    19201 cttttttact cgttttatga taatacttgt atcgaattga tttggaggta attacataaa
    19261 aacaaaaaaa atatagcaac tctctataag aaagttgcta tattgataat tataccggcg
    19321 gccggggtcg aaccggcacg tcctcaacgg acactggatt ttgagtccag cgcgtctgcc
    19381 aattccgcca cgccggcaaa tttaaaaata ataactgggg tagctggatt cgaaccaacg
    19441 catgagggag tcaaagtccc ttgccttacc gcttggctat accccaagaa taaagggcga
    19501 atgatgggaa tcgaacccac gaatgccgga gccacaatcc ggtgcgttaa ccacttcgcc
    19561 acattcgcca tcataaaaga tgttatttaa tttctcaata aaaaactaag atgaagacat
    19621 cttagtcaat accggcggcc ggggtcgaac cggcacgccc tcaacgggca ctggattttg
    19681 agtccagcgc gtctgccaat tccgccacgc cggcaagttg atttattagt actaaggcgg
    19741 taaccggatt tgaaccggtg atgaaggttt tgcagacctc tgccttacca cttggctata
    19801 ccgccattat actattatca atctataaaa taaagaataa attatagaaa ctggggtagc
    19861 tggattcgaa ccaacgcatg agggagtcaa agtcccttgc cttaccgctt ggctataccc
    19921 caagaataaa aagggcgaat gatgggaatc gaacccacga atgccggagc cacaatccgg
    19981 tgcgttaacc acttcgccac attcgccatg gcaggggcag caggaattga acccacacta
    20041 acggttttgg agaccgctgt tctaccttta aactatgccc ctataaaatg gaggagagtg
    20101 gattcgaacc actgaaccct aaggaacgga tttacagtcc gtcgcgttta gccacttcgc
    20161 tactcctcca tggtggcgcg ggacagaatc gaactgccga cacacggagc ttcaatccgt
    20221 tgctctacca actgagctac cgcgccatat tttaaaatta ttaattgaat aacaagaacg
    20281 acggttccga cgggaatcga acccgcgatc tcctgcgtga caggcaggca tgttaacccc
    20341 tacaccacgg aaccagttca ttatggaggt taacgggatc gaaccgctga ccctctgctt
    20401 gtaaggcaga tgctctccca gctgagctaa acctccaaca ttcaattaaa atgacccgta
    20461 cgggattcga acccgtgtta ccgccgtgaa agggcggtgt cttaaccgct tgaccaacgg
    20521 gccaggtaaa tttgctacgg agagtaaggg attcgaaccc ttgagacagt ttggcaccat
    20581 ctacatgatt tccaatcatg ctccttcggc ctctcggaca actctccaga gtgaaagaag
    20641 ctcaatactc tttctcaaaa tgag
//
LOCUS       DACDLM010000052        20360 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.052, whole genome shotgun sequence.
ACCESSION   DACDLM010000052 DACDLM010000000
VERSION     DACDLM010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20360
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.052"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            292..1431
                     /locus_tag="IV356_001940"
     CDS             292..1431
                     /locus_tag="IV356_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HAP9015611.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLARHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHSIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(1498..2073)
                     /locus_tag="IV356_001941"
     CDS             complement(1498..2073)
                     /locus_tag="IV356_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP9015612.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQVGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(2078..3052)
                     /locus_tag="IV356_001942"
     CDS             complement(2078..3052)
                     /locus_tag="IV356_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HAP9015613.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPVDIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGLDGLGDTNFPMVLAKQAESL
                     HAVDFLTDYFKEKTDTSVIALGPLTNIASALKNSPSVGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFEKLKQPIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIDESICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(3076..3120)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            3335..4303
                     /locus_tag="IV356_001943"
     CDS             3335..4303
                     /locus_tag="IV356_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP9015614.1"
                     /translation="MVIFYFILILIFIGISYHFLSYFYAKKLVRAGVQRGYDWYEETG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGIPKTIKSYDGLKLAGQMFLQPTQQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLIPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPDASIILHGSSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMIMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            4416..4694
                     /locus_tag="IV356_001944"
     CDS             4416..4694
                     /locus_tag="IV356_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAP9015615.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARREGKKIIPSCPYAKKEFEKKPEYHDVLRQS"
     gene            4812..5048
                     /gene="secG"
                     /locus_tag="IV356_001945"
     CDS             4812..5048
                     /gene="secG"
                     /locus_tag="IV356_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HAP9015616.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAVWMILLFVLAFLSSK"
     gene            5160..5906
                     /locus_tag="IV356_001946"
     CDS             5160..5906
                     /locus_tag="IV356_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAP9015617.1"
                     /translation="MKQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKADYTV
                     YAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFAVRA
                     LEEESVIGGGFFCSPLSPVETNVPENFEKYVRQVLKIAGKSEKEINEKAVSYRSLAEH
                     QLMDIQDQAAIAESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQWYPE
                     SGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            5909..8266
                     /gene="rnr"
                     /locus_tag="IV356_001947"
     CDS             5909..8266
                     /gene="rnr"
                     /locus_tag="IV356_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HAP9015618.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILVEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSDEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDIVGRRDLRDQLIVTIDGEDA
                     KDLDDAVTVKKLENGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHEIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILEMMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKSGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            8288..8752
                     /gene="smpB"
                     /locus_tag="IV356_001948"
     CDS             8288..8752
                     /gene="smpB"
                     /locus_tag="IV356_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HAP9015619.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            9054..9773
                     /gene="atpB"
                     /locus_tag="IV356_001949"
     CDS             9054..9773
                     /gene="atpB"
                     /locus_tag="IV356_001949"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HAP9015620.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            9826..10041
                     /gene="atpE"
                     /locus_tag="IV356_001950"
     CDS             9826..10041
                     /gene="atpE"
                     /locus_tag="IV356_001950"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HAP9015621.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            10132..10656
                     /gene="atpF"
                     /locus_tag="IV356_001951"
     CDS             10132..10656
                     /gene="atpF"
                     /locus_tag="IV356_001951"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HAP9015622.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            10643..11185
                     /locus_tag="IV356_001952"
     CDS             10643..11185
                     /locus_tag="IV356_001952"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HAP9015623.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            11208..12764
                     /locus_tag="IV356_001953"
     CDS             11208..12764
                     /locus_tag="IV356_001953"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HAP9015624.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEETLNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            12778..13680
                     /locus_tag="IV356_001954"
     CDS             12778..13680
                     /locus_tag="IV356_001954"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HAP9015625.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            13703..15109
                     /gene="atpD"
                     /locus_tag="IV356_001955"
     CDS             13703..15109
                     /gene="atpD"
                     /locus_tag="IV356_001955"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HAP9015626.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            15123..15545
                     /locus_tag="IV356_001956"
     CDS             15123..15545
                     /locus_tag="IV356_001956"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HAP9015627.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            16014..16244
                     /locus_tag="IV356_001957"
     CDS             16014..16244
                     /locus_tag="IV356_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HAP9015628.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            16341..17642
                     /gene="murA"
                     /locus_tag="IV356_001958"
     CDS             16341..17642
                     /gene="murA"
                     /locus_tag="IV356_001958"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAP9015629.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNCPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            17655..17831
                     /locus_tag="IV356_001959"
     CDS             17655..17831
                     /locus_tag="IV356_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAP9015630.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            17966..18262
                     /gene="yidD"
                     /locus_tag="IV356_001960"
     CDS             17966..18262
                     /gene="yidD"
                     /locus_tag="IV356_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HAP9015631.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            18326..18709
                     /locus_tag="IV356_001961"
     CDS             18326..18709
                     /locus_tag="IV356_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP9015632.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHH"
     gene            18878..19762
                     /locus_tag="IV356_001962"
     CDS             18878..19762
                     /locus_tag="IV356_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP9015633.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            19879..20112
                     /locus_tag="IV356_001963"
     CDS             19879..20112
                     /locus_tag="IV356_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HAP9015634.1"
                     /translation="MSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYGP
                     KEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            20200..20280
                     /locus_tag="IV356_001964"
     tRNA            20200..20280
                     /locus_tag="IV356_001964"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20234..20236,aa:Tyr,seq:gta)
     gene            20287..20358
                     /locus_tag="IV356_001965"
     tRNA            20287..20358
                     /locus_tag="IV356_001965"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20319..20321,aa:Gln,seq:ttg)
BASE COUNT         6759 a         3566 c         4425 g         5610 t
ORIGIN      
        1 tttttttgca actagcttct gtatatgatg tttacaaaga atggtacaag aaaagatcat
       61 ccttgaaaaa ggaaagctaa caataactag catcatataa gagcttttaa ggatagaaca
      121 gtagaatagg aatctatggg caagtcctct cgtataaata aaataggagg gaagtagcag
      181 catatttttc ataaagtggc tctctttctt catttttact ttggttgctc ctatttgaaa
      241 attcgagcac actcaaatac aataaaaaga aatggcaagg gagaggatta gatgaaaaaa
      301 gaagaaaaaa tcgcgatttt acaagagatt atccgaatta aatcagtgaa tggaaacgaa
      361 ggtgaagtag cagcctattt gaataagctt ttggcaaggc atgacataac aggagagatt
      421 gtttcttaca gagatggtag agataatttg attgctcgtt accaaaaggg ccaatcagga
      481 aaagtgttag gcctatctgg acatatggat gtcgtggcgg ctggtgatga atcgtcttgg
      541 acctatgcac cctttgcagc agaaatccat gggaaccgtt tgtacggacg tggtgctaca
      601 gatatgaaga gtggcttggc agcaatggtg attgccatga tcgaactgaa agagtcagga
      661 aaaccattta acggaacagt caaattatta gccactgtcg gagaagaagt gggtgaacta
      721 ggtggggaac agctcacgaa agcaggctat gtagatgact tagatgcctt gatcatcgga
      781 gagccaacca attacagttt gatgtatacg cacatgggat caatcaacta tacagtcacc
      841 tcgcacggaa aagaagcgca tagctctatg ccagaccaag gttataatgc aatcaatcac
      901 ctaaatgaat tcattacgaa agcaaatgct gaaatgaatc acctcgctga aacaatcgag
      961 aatcctgtcc taggaaaaac aatccataat gttacattga tcagtggcgg gaatcaagtc
     1021 aacagcatcc caagccatgc gcagctccaa gggaacattc gatcgattcc agaataccca
     1081 aatgataaaa tcattgcatt gctgcaatca atcgtcaatg aattgaatca agagacagac
     1141 tatcatttgg aattgatgat cgattacaac aaaatacctg tcaaagctga tccagattct
     1201 cctttgattc attccattca gcaacaattc agccagccat tacctttagt tggagcggca
     1261 gcaacaacgg atgcagccga atttacgaaa gctaaccatt ccttcgactt tgtcgtcttt
     1321 gggcctggtg tcgttacttt gcctcatcaa gtagatgagt atgttgaaat cgataattat
     1381 ttggatatga tcgaaaaata tcaaggaatt attttatcct acttagcgta agattttttt
     1441 aataaatgaa aaaacagagc cagattagca ttattttgct aatccagctc tgtttattca
     1501 gcctattttt ctttttgaat atatcaagcg ttggggcaac atagtgatga ctaatgaaac
     1561 aacgacgata gacaacaagc gatcaaggta gtctgtaccc acctgtacca agatcacact
     1621 tgttgtctga cttaaaccta acccatgtaa tagctgaacg atcatactgg atcctgagga
     1681 ggtgatcccg ccaaataact gaacggtaat gatcgaagaa acgatcgttc caggtaccga
     1741 caaaatcaaa gcgagtaata acagtttcaa gctgttttta tctttgccga gatatcttgg
     1801 caaaatcaat ccagcaagca agcctgtgag aatttggatt ggcgaataat acagagaaaa
     1861 aatatctgta gtcactccac ttaaaatacc gctggacaat cctgtcagca ttccaggtac
     1921 aggcccaagc aatgcaccag caaaaatcgt tccgatagaa tcgagataga ttggcaaacg
     1981 aagccataaa gcaatcgttc ctccaatata attgatccca atacacaaag ccatcactgt
     2041 aagtacgcga gttgccattt tgtttttatt cattttgtta gcccatcttt aacctttcca
     2101 aatctttcat aatcgtttct tcttgtgcat ttaaaagaac ggttaaaaac tttcggaaaa
     2161 aaagacgagt atctactttt gtcataattt tactgttagc aggtttctgc caaaattcat
     2221 aacgatcaac caatgtttgt ccgcgactta ttccttgagt ttctacagca gtgaagcttt
     2281 taaagccttc acagatggac tcatcgataa aataagcaac agctaatgga tcattgatga
     2341 cacatcctaa gattctttct tgtttccagt gaaagtcaaa ataaaaacga gtgatcgctt
     2401 ttagatactc tccctcttca ggattcattt ggcagcaata ttcaaggata gtcggtgtca
     2461 agacgatttc tcttgtcaca tctaacccaa ccatttctat cggttgtttg agcttttcga
     2521 atacataaga agctgcttca ggatcacacc agtaattgta ttcagcaact ggtgaacagt
     2581 taccatggct tttgtaagtt ccgcccattg agacaaaacg atccatatgt ttcccaacag
     2641 atgggctgtt tttcaaagca gaagcgatat tggtcaaagg ccccaaagca atgactgatg
     2701 tatctgtttt ttctttgaaa taatcagtca gaaaatcaac tgcatggagc gattctgcct
     2761 gtttggctaa gaccatcggg aaatttgtgt cccctaatcc atccaaccca tgagtgtctt
     2821 gcgcactaat gaaaggttgc ttcaaaggtt tttccattcc ttgataaaca gggatatcta
     2881 aacgatcaca gcgctccaaa catttcagca cattctgcgt accgatatct acagggacat
     2941 tcccgcaaac gacggtaata gcaactactt cgatatcagg ggatttgaca gctagtgata
     3001 aagctaaagt gtcgtcgatc cctggatcgc aatcaataat tactttacgc attatttcca
     3061 atctcctttc tttagagata cttagttttt tattctggga agtttccgaa ccagtccaag
     3121 acgagtgtct tgtttataat gcacgaaatt agtatactgg cttttattgt gaatgtaaat
     3181 gctctcttac aagtaaatct attgagaaga actttaagta aatgatacaa tgaaaaagaa
     3241 atggaattta cgtgtgccga agaaaaagaa tcctattgat cggtatattg tataataaat
     3301 agattatagt ttggcagaaa gcggcgggtg tacgatggtt attttttatt tcattcttat
     3361 tctgatattt ataggaatca gttaccattt tctttcttat ttttatgcaa agaaattagt
     3421 aagagcgggg gtacagagag gctatgactg gtatgaagaa actgggcacc gcttgatgga
     3481 tcctgctgca gtcacgtcag tagaaaaaaa gcgacaaaaa ttagaagaag agtgtgaaag
     3541 cttctgggaa caaggaatac cgaaaacgat caaaagttat gacgggttga aactagctgg
     3601 acagatgttc ctccaaccaa ctcagcagaa taaatgggtc atttgtgtac atgattatcg
     3661 aagtacaggg aaaagagata tgtctcatat aggtaaaaga tatgcagaga aaggattcaa
     3721 cgttcttata cccgatttac gtgcgcatgg agaaagtgaa ggagaaatca tcggaatggg
     3781 atggctagac cggctagatt taattgcatg gatccaactc atcttagatg aacaaccaga
     3841 tgcatccatt attttgcacg gcagttcgat gggcgcttct actattatga tggcaagtgg
     3901 tgaaaagctt ccatctgcag tcaaaggatt tatcttagac agcggatatg tttctgttta
     3961 tgcggaattt cggtatatgt taagtaaaat cacggtcttt cctaaaaaaa tgatcatgag
     4021 atatgcgaat cactatgctc agaaatacgc aggttattct ttaaagcaag catcagctac
     4081 aagacagctt ggtagtaacc atttgccttt gttagtcatc catggtgaaa gagatcattt
     4141 tgttcctaca gaagcagcat acacgattca aaacgctacg gcaggggata aagcattact
     4201 gcttgttcca gaagcagaac atttggaagc atcgatgaaa gatccgaaaa cctattggac
     4261 agtgattttt tcatttattg aacaaagaat aacgatggat tgattttctc ttcctttttg
     4321 taagcaacac gaggataaat aattgtttat agaccatgag actgttaaaa taaggtagga
     4381 ataaaaaaat atcagttatt tgaggagtgc ggcatatgga aatcaaagag gaaaaaaatc
     4441 gtcttgcttt attcaatgat gagcaacaag aaatcggaga aatgacatgg tcggatgcgg
     4501 ggccagacat catgatcatt gaccatacat ttgtcgatcc agcatatcgt ggtcaaaaat
     4561 tagctgaaaa gctagtgtat actggagtag aactagcaag acgagagggg aaaaagatta
     4621 tcccttcatg cccttacgca aaaaaagagt ttgagaagaa accagagtat catgacgtct
     4681 tacgccaatc ataataataa cagctgaaag atttgcactt tcagctgttt ttccatttat
     4741 atagagttgt cacggagttt tatctatgat aaagttaaag agacgatatc ttttgggaag
     4801 gaggctgcta tatgtataat ttaattttgg gaatcgtgat cgttttatcg attgttatgg
     4861 tcattgcgat tatgatgcag ccaagcaagc aaaatagtgc agcgagtgca tttaccggcg
     4921 gtgcggatca actattcggc aaacaaaaag ctcgcggctt tgaagctgtc atgcagcgat
     4981 caactgcagt catgggagct gtctggatga tcttattatt tgtcctagca tttttatctt
     5041 cgaagtagtc gaataagcct ctcgcacaac ggcgggcggc tttttttatt gcaaagagaa
     5101 cgcttaagaa gaagttatga aagaaactat ggtaaaatga ggcgaaagag gtgaaacgag
     5161 tgaaacaatt accaaaaccc ctttatgcaa aacatggaaa acgagcagtt ttgctgcttc
     5221 atgcgtactc aggaagtcca aatgatgtcc ggatgctcgc acggttttta gaaaaagcag
     5281 attatacagt ctatgcgccg ctatttaaag gacatggaac gatggagcca tatgatatct
     5341 tgcaagaaaa agcagaaagc tggtgggcag atactaaaaa agctatccat tttttacagt
     5401 ctgaacagtt ttctgatatt gccgtattgg gattatcgat gggtggcatc tttgctgtac
     5461 gggcactaga agaagaatca gtaattggcg gcggtttttt ctgttcgccc ctgtctcctg
     5521 tagaaacaaa cgtgcctgaa aattttgaaa aatatgtacg tcaagtgctg aagatagcag
     5581 gcaaatcaga aaaagaaatc aatgaaaaag ctgtgtctta ccgctcgtta gctgaacatc
     5641 aattaatgga tatacaagac caagcagcaa tcgcagaaag tagactatca gatatccaac
     5701 agccaatatt tttagctcaa gctgggaaag atgaaatgat cgacccaaat ggtgtatttg
     5761 aaacggcacg caaattgagc cgccaacgag tgacacttca atggtatcct gaaagcggtc
     5821 atgtgattac agttggcaca gcaagacgcg aattagaaaa agacgtgttg gaatttttag
     5881 aaaaattacc ttggaatgag gaataaatat gacaaaagaa acaataaaag agaaaattct
     5941 ctttttcatg gaaagcagtc gcaaacgtag tttttctatg gaagaaatcg ctgaaggtct
     6001 aggctttcaa aaaagcgatg attttaaatt actagtacaa acgattgctc aaatggaaag
     6061 agaacagagt atcgttttca ataaaaaagg aaaagtcaaa cttcctttaa aaccgatctt
     6121 ggtcgaaggg acatttcggg caaatgaacg aggatttgga tttgtaacga ttgatcccga
     6181 agaagatgat atctatatcc cgaaagaagc gactggcttt gcaatggatg gggataccgt
     6241 agcaattgat atcatgaagc gagcaaatac agatatggat cgcggagcag agggaaaagt
     6301 agtggagatt cgagaccgag cgactactca gttagccgga gaatttgttg cttattcaga
     6361 cgaagagata caggaaacgg atctttatgg tgtggtcatc ccgaaagata gaaagcttaa
     6421 ccaattcaaa gtgtatgcag cggcagaggg agttcgtcca gttgacggaa gtattgtatt
     6481 gatcgaactg acccattacc ctgaaaaagg gtatgcaact agtttagaag ggataatcaa
     6541 gcaagtgatt ggtcataaga atgaccctgg catggatatc ctctcgattg tcgtggctaa
     6601 cggtattcct acaaaatttc ctgatgatgt gttatctgag gcagatgaag ttccagacca
     6661 gatcagcgaa aaggatattg ttggacgcag agatttaaga gatcagctca tcgttacgat
     6721 tgatggagaa gatgcaaaag atctagatga tgcagtgacg gtcaaaaaat tagaaaatgg
     6781 taattatttt cttggagtac acattgcaga tgtatcttac tatgtgacgc aaggcagtca
     6841 actggacaga gaagcatacg aaagaggaac aagtgtctat ttgaccgatc gagtgattcc
     6901 gatgatccca caacgtttat ccaatggtat ctgttcattg aatccccatg ttccacgact
     6961 caccatgagt tgtgaaatgg agatcgatcc aaatggacaa gttgtctctc atgagatttt
     7021 tccaagtgtg atccaaacaa cagaacggat gacctacaca gctgtcaatc aaatcttaga
     7081 agatcaagat gaagaaacga tgcaacgtta tgctcagctc gtgcctatgt tccaagaaat
     7141 gggtgaattg catcgaatcc ttgaaatgat gcgaatcaaa cgtggagcga tttcttttga
     7201 ggatcgtgaa gcgaagatcc ttgttgatgc tgaaggacac ccaaatgata tccagctaag
     7261 aagcagaggg ataggtgaac gcttgatcga atcctttatg cttgctgcca acgaaacggt
     7321 agctgaacat tataataaat taaatcttcc gtttatttat cgaatccatg aacagccaaa
     7381 agaagaaaaa atgcagcgct tctttgattt tgcttcagct ttgggcattc tggtccgagg
     7441 aacgaaagga acgatcacac caaaagattt acagcatgtg atcgaaggag tagaagacaa
     7501 accagaagct gcagttatca atactatgtt gctaagaagc atgcaacaag cacgctattc
     7561 agaagacaat tttgggcatt atggcttagc ggcagattac tacacacact ttacatctcc
     7621 tattcgacgc tatcccgatc taatcgtcca tcgtctgatc cgttcttaca gtgaagataa
     7681 aagtgaaagc aatcaaagtt cgtgggctgc ggaacttcct gaaattgcag atcatagttc
     7741 taagatggaa cgtcgtgcag tagaaacaga acgtgaagta gattccatga agaaagcaga
     7801 attcatgatg gacaaagtgg gagaagaatt cgatgggatc atcagctctg ttgtgaaatt
     7861 cggcctgttt atcgaactgc cgaatacagt agaaggattg atccatatca atgaattgaa
     7921 acaggactac ttccattttg ttgaaaatca tttagctctt gtaggtgaaa gaactggtct
     7981 gacttttaaa atcggacaaa aagtgcgcgt aaaagtagtc aaagctgatc cagatgaacg
     8041 agcagtggat tttgaactcg tttccgcaga agaggtcact gcgttggaac gtccaaaagc
     8101 acgcaatgga aaatctggaa aacgagaagg aaaacaagca ggcaaacgct cagaaaaaaa
     8161 tggcaagaag aacaaacgat atagtgatag taagcaaacg ttcggtaaga aaaaagggaa
     8221 aaagccattt tacaaaggtg tcaaaaagaa gaaaaagaaa aaataaaatg agttggagga
     8281 aacagctatg ccaaaaggcg agggaaaact aattgcacaa aacaagaaag ctcgccatga
     8341 ttattcgatc atcgacacga tggaagcagg gatggtcttg caaggaacgg agatcaagtc
     8401 gatacgaaac agccggatca atctgaaaga tggatttatt cgcgtccgca acggggaagc
     8461 tttcttgcat aatgttcata tcagtcctta tgaacaagga aatattttta atcatgatcc
     8521 gttgcgcacg agaaagttat tattacacaa gaaacaaatc gttcgtcttg aaaacgaatt
     8581 gaaaaacact ggaatcactg ttgttccttt aaaagtctat attcgtaacg gctatgccaa
     8641 ggtattgatt ggtctggcaa aagggaaaaa atcgtatgat aaacgggaag atttgaaacg
     8701 aaaagatatc gatcgacaaa ttgatcgaac attaaaaaat ttctctagat aatttcatta
     8761 tcctttttcg catattcggt gcttttgctt ttacttaatg ataaaatttg ttagcattta
     8821 atctgataaa acatgattat cacaggtttt ttcttagatc aggagcaccg tgcatgggga
     8881 aaaattcgct tcgtttttga ctgaaataaa aaagtgtcta attttcatga aaatgttttg
     8941 aattttctgt ttcatggtgg tatgataccg tgtggttaga aaccgattgg aaaaaaccag
     9001 atacgcacat gaattgattt tatgtgaatt tcggggaaaa gaggtgaaat ggattggatg
     9061 aacgctcgct aacgtttcac attggaccaa tttggtttga tggtacagtt tgtataatgg
     9121 tgttactgac ctgtttgatt gttttcttct tagcttactt ttttacaaga aatcttaagt
     9181 tgaaaccaac aggcaaacaa aatgcgatag aatgggtcat tgattttagt cgaggaatcg
     9241 taacagataa tctgcctaga aaagaattga gcaatttcca tttgttggca tttacattgt
     9301 ttttatttgt ttttgttgca aacaacatag gtttagtaac aaaaatcgtc ttacctaacg
     9361 aaacaacact ttggaaaagc ccgacagcag acccgtttgt tactttaact ttggcattta
     9421 taatgatctt acttactcac ttattcgggg tgaaaaagtt aggcttcaaa ggatatttcg
     9481 taaattcgtt cttgaaaccc tatagtttta tgtttccgat gaaactgatt gaagaattta
     9541 caaacttatt aacacttgct ttacgtcttt atgggaatat ttatgcgggg gaagttttgc
     9601 taaccttgat tgcaaaaatg atgacaagct taggctggtt ctcattacca ttagcaattc
     9661 cattagagat ggtctggatc gcgttctcct tgtttattgg gagcatccaa gcatttgtct
     9721 ttgtcacttt gtcaatggtt tatatgagcc ataagattga agtagaagaa taatactcgg
     9781 ttaaaaaaca aactactatt tatctatttt aggaggaaaa caattatgaa ttatatcgca
     9841 gcagcaatcg caatcatggg agcagcaatc ggagccggtt atggtaacgg tcaagttatc
     9901 tctaaaacaa tcgaatcaat ggctcgccaa cctgaaatgt ctggtcaatt ccgtacaaca
     9961 atgtttatcg gggtagctct agttgaagct gttcctatct taggggtagt tatcgccttg
    10021 attctagttt ttgccgttta attgaatcag tattaaggca gaaacaacat cgtttgttac
    10081 tgctttttta catggaaact agaaatactc caaagaaagg aaggctcgcc tatgctgaat
    10141 caattggcaa ttgcagaagt tggcaatgcg atgttaggta atatcatcgt tgtcagcggc
    10201 tcatttttga tactactggc tctcttgaag cactttgctt ggggaccaat cagcgatatt
    10261 ttgaaaaaac gtgaagacaa gatcgccaat gatttagatt ctgcagaaca atctcgcatc
    10321 aactcagcga aaatggaaca agaacgcgaa caacaattgt tagcctctcg ttctgatgca
    10381 gctgatatca tcaaaaatgc gaaagaaagt ggagaattaa gccgccaaaa tattttgaag
    10441 gatgctcaag aagaagcagc tcgtctaaaa agcaaagccc aagctgatat cactgtagaa
    10501 cgtgattcag cgctgaactc tgtaaaagac gacgttgcag aactctctct tcaaatcgcg
    10561 gaaaaaatct tgaacaaaga attatctcca gaaatgcatg aatcattaat caatcaatac
    10621 attgaaggtc taggttcttc aaatgaaact agataaatat acagtaggaa gacgttacgg
    10681 gaaagcttta tttgaactgg cgatcgattc aaatcaagca gaagaaatct atcaagatct
    10741 cgtaagttta cgtcaaatct atgaacaagt acctggatta gggaatatgt taagtgatgt
    10801 tcgtctagaa cctcatgaaa aacgagaaat catggacaag cttgtcagcg gttatgatgg
    10861 aatcgttaaa aactttttag aagttgttta tgagtataac cgaatggatg accttttgtt
    10921 catgattgaa gaatatgaac gtcgatatga tgaacatcaa gggttactat tgggaagtgt
    10981 cacaacagca gtcccacttt cagacgaaca acgaatacaa ttagaaaaga atgttgcaaa
    11041 aacaatggac tatcaatcag ttgaattaaa acaaatcgtt gattcttcta ttattggtgg
    11101 cgcgattgtt gaagccaacc atcgagtaat cgacggaagc attcgcacgc aattagaaaa
    11161 aatgcgtaat caattaaaca gatagtacaa agaggtaggt gaatcgaatg gccatcaaag
    11221 cagaagaaat tagtgccttg attaaagaac aaattgaaaa ttatcaaaac gtgctttcag
    11281 tcgaagaaat cggtaccgta acttatgtag gtgacgggat cgctcgtgca catggtttag
    11341 aaaacgcgat gagtggtgag ttgcttgaat tttcaaacgg ctcatacgga atggcgcaaa
    11401 acttagagtc aaatgatgta ggtatcatta tccttggcga tttcgagtcc attcgtgaag
    11461 gagataaagt aaaacgaaca ggtaagatca tggaagttcc agttggagag gccttgatcg
    11521 gtcgggtagt caatccgcta ggtcaaccaa tcgacggact aggtgaaatc gttactgaca
    11581 aagctcgtcc agtagaagcg atggcaccag gtgttatgca acgtaaatct gttaacgaac
    11641 caatgcaaac agggctaaaa gcgatcgacg cccttgtgcc aatcggacgc ggacaacgtg
    11701 aattagtcat cggtgaccgt aaaacaggga aaacttctat tgcgattgat acgatcatca
    11761 accaaaaagg tcaagatatg atctgtatct atgtagcaat cggacaaaaa gattctacag
    11821 ttcgtacaca agttgaaaca ttgaaaaaat atggcgcaat ggattacaca atcgttgtga
    11881 atgccggtgc gtctcaacca gcaccattac tttatatcgc accatatgct ggtactgcaa
    11941 tgggtgaaga attcatgtac aacggtaaac atgtattgat catttttgat gatctttcaa
    12001 aacaagctgt tgcttatcgt gaactttcct tgctacttcg ccgtccacca ggtcgtgaag
    12061 cttatcctgg ggatgttttc tacttgcact cacgtttatt agaacgtgca gcaaaattaa
    12121 gtgatgatct aggcggcggt tcaatgactg ctttgccatt tgttgaaaca caagctggag
    12181 atatctctgc ttatatccca acaaacgtta tctcaatcac tgacggacaa atcttcttag
    12241 aaagcgactt gttctacgcg ggtactcgtc cagcggttga tgccggacta tctgtctctc
    12301 gtgtaggggg ttctgcgcaa atcaaagcaa tgaaaaaagt tgctgggact ttacgtctag
    12361 acttagcaag ttatcgtgaa ttagaagcat ttacacaatt cggttctgat ttggatgcgg
    12421 caacacaagc aaaactaaat cgtggacgcc gtacagtaga aatcttgaaa caaaaactgc
    12481 atgcaccgct agctgttgag aaacaagtag tgattttgta tgccttgaca catggattct
    12541 tggacagtat ccctgtagac agtattttag acttcgaaca tgaattattc gaatatctgg
    12601 ataccaatca ttcagatatt tttgaaacaa tccgtacaac aaaagatctt ccagaagaag
    12661 aaacgttgaa cagtgcgatt caggaatata aagacatgtt cttagctaca aaaggaaata
    12721 attcctctac agaagataaa ttgaaatcca ttcaaaatgc atagtgaggt gagatgaatg
    12781 ggtgcttcat taaatgaaat caagacacgt atcgcttcaa cgaaaaaaac gagccaaatc
    12841 acgcgggcaa tgcagatggt gtctgcttct aagttgacaa aatctgaagc ttcttcacag
    12901 aagtttcagg tttatgcaac aaaagtaaga gaaatcgtta cgcatttgac tgctactcag
    12961 ttaaatgata ttgcctcaga aaatcctaga ggggatatca attacaacag catgctgctc
    13021 agccgtcctg tgaagaaaac cggttatatc gtcatcactg cagatggcgg tctggtcggt
    13081 ggatataaca gttcgatatt gaaacaaacg atgtctattt tagaagaaga ccaccaatca
    13141 cccgatgatt acgtgatgat cgcaattggc ggaactggtg cagacttctt taaagcacgc
    13201 ggtatcaacc tagcatatga gctgcgcaat ttatctgatc agccaagctt tgatgaagtc
    13261 cgcaaaatcg taaatatggc aacaactatg taccaaaacg aagtattcga tgaattatac
    13321 gtatgttata accatcatat caattcgcta actagtcagt ttcgtgtaga aaaaatgctg
    13381 ccaatctcag acttagatcc agaagaagca acgactttcg aacaagaata tatttttgaa
    13441 ccttcaaaag aagaaatctt gtctcagtta ttgcctcagt atgctgaaag tttgatctac
    13501 ggtgcgatcg ttgacgccaa aacagcagaa catgctgctg gtatgacagc aatgaaaaca
    13561 gcaactgata atgctgctaa tatcattgat gagctgacgg tttcttataa ccgtgcaaga
    13621 caaggggcta ttacccaaga aattaccgaa attgttgccg gagcttcggc actagaatag
    13681 tattgagatt ggaggaaaaa agatgagttc aggcaagatt gttcaagtaa tcggtcccgt
    13741 tgtcgacgtg gaattttctt tagaccaatc cttaccagat atcaacaacg cattagttgt
    13801 ttataaaaat gacgaaaata aatcaaaagt tgttcttgaa gcagcgttag aattagggga
    13861 cggagtgatc cggaccattg cgatggaatc aacagatggt ttacaaagag gaatggaagt
    13921 cattgataca ggcaaagcaa tctctgttcc tgtaggtaaa gaaacattag gtcgcgtatt
    13981 caacgtacta ggagatacga tcgatttaga aacacctttc ccagaagatg cggaaagaag
    14041 cgaaattcat aaaaaagcac cagcctttga cgaattaagt acaagtacag aaattttgga
    14101 aacagggatc aaagttatcg atttgcttgc cccatattta aaaggtggga aagtcggact
    14161 attcggtggt gccggtgttg gtaaaaccgt actgatccaa gaactgatcc ataatatcgc
    14221 ccaagaacat ggtggtattt ctgtatttac cggtgtaggt gaacgtactc gtgaaggtaa
    14281 tgacttgtat tatgaaatga aagattcagg agttatcgaa aaaacagcca tggtgttcgg
    14341 acaaatgaac gaaccaccag gtgcacgtat gcgtgttgct ttgactggtt tgacgattgc
    14401 ggaatatttc cgtgatgtag aaggtcaaga tgtactgttg tttatcgaca acattttccg
    14461 tttcactcaa gctggatctg aagtatcagc cttgttagga cggatgcctt ctgcggttgg
    14521 ttatcaacca acattggcaa cagaaatggg tcaattgcaa gaacgtatca catctacgaa
    14581 aaaaggttcg atcacatcga tccaagcaat ctatgtgcca gccgatgact acactgaccc
    14641 ggcgccggca acagcattcg cccatttgga tgcgacaacc aacttggaac gtaaattaac
    14701 agaacaaggg atttatccag cggtagatcc attggcttct tcttcaagtg ctttagcacc
    14761 tgaaatcgtg ggagaagaac attataaagt agcaacagaa gtccaacacg tattgcaacg
    14821 atatcgtgaa ttacaagata tcattgctat cttaggtatg gatgaattat ccgatcaaga
    14881 aaaagtgtta gtttctcgtg cccgcagagt ccaattcttc ttgtcacaaa actttaacgt
    14941 ggctgaacaa tttactggtc ttccaggttc atatgtccct gtagaagaaa cagtgaaagg
    15001 attccgcgaa atcttggaag gcaaatacga tgatcttcct gaagaagctt tccgaagtgt
    15061 tggccgaatc gaagacgtcg tagaaaaagc gaaaacacta ggctactaga aaggggtgcc
    15121 ccatggatca atatttaaca gtaaatgtgg taactcctgc cggtttggtc tatgatcacc
    15181 atgcagctat cgtcgttgca cgtacgacag ctggtgagct tgggattttg cctaaacatg
    15241 caccaatcat cgttccattg acgattgatg aagttcgtgt aaaacgaaca gattcagata
    15301 cccacgtcga ttggatcgct gttaatggcg gaatcatgga agttcgtgat aatgttgttt
    15361 caatcgttgc tgatagtgcg gaacgtgaac gtgatatcga tgtatctcgt gcggaacgtg
    15421 caaaacaacg cgcagaacgc caaatcgaag aagcaaaagc aaaacaagat acgaacgaat
    15481 tgaaacgggc aactgttgcg ttgcaccgag caatcaatcg tatcaaagta tctaagcact
    15541 cataaaatga gatgcggatg tttatccgtg tttaagaaca gtaaaaagag gttatgacag
    15601 aagtggtcag cttcaagaca taagaaggaa tttacgaaaa ttgcttctca aatttttgtg
    15661 aaatctcagc ttatttttcg aagaagctac ttctggaaca ccgtatatca gaggttgtga
    15721 aatcagcgtt ttgtcctgag tattagagaa acaaatggaa aatagttcct catattttgc
    15781 cgttttttga gctaataccg agggtcagat gattgaacac cgtttatttg gaataaggga
    15841 ctgcgacaag acttttgtct cagtcccttt ttttgcatat ttttagcatt tatttcctaa
    15901 aaaatgtaag gggattccta tatttttaag tatacttgtt tttcctttta tacattttat
    15961 ggtattatca ttttattagt tattataaaa caatcgttag aaaggacgtc attatgcaag
    16021 tatacggaat tgatgcggtg cttcgaatcg tgagtcattt ggcgtttatc tacttagcct
    16081 tctggtcttt acgttcgtta cgcattgaaa cttttttcag accaatgcat aatacgcaaa
    16141 ttagaatggc aatcgtactt ttttcaattt ttttagggta cactgcaagt aattttttct
    16201 tagaagttat cgctttatgc cgaaatcttt tcgttagcct gtaaatttta aaaaaaggta
    16261 ctattttaaa agcaaggatg ttataataga aaagattttg agtaagtgta tgctcattgg
    16321 aattttttgg agggaacaac atggaagaga tcatcgtaag aggtggcaat caattaaatg
    16381 gaacagtaag aattgaagga gctaaaaatg ctgttttgcc tattttagct gctagtttgt
    16441 tagcagaaga aggtattacg acattagaca acgttccgat tctttctgat gtcttcacta
    16501 tgaatcaagt gattcgtcac ttaaacgtag atgtagattt tgatgaacaa aagaatcaag
    16561 taacaatcga cgcttcaaga caattagaaa tcgaagcgcc ttatgagtat gttagtcaaa
    16621 tgcgtgcttc aatcgttgtg atgggtccgc tacttgccag aaatggacat gcaaaagtag
    16681 ctatgcctgg tggatgtgcg attggtaaac gaccaatcga tttgcattta aaaggatttc
    16741 aagctttagg agcaaaaatt attcaaaaaa acggctatat cgaagcaatt gcggatgaat
    16801 tgatcggtaa cacgatttat ttagatttcc ctagtgtggg tgctactcaa aatatcatga
    16861 tggctgccgt aaaagcaaaa ggaacaacca tcattgaaaa cgtagctcgc gaaccagaaa
    16921 tcgttgattt agcaaacatt ttgaataaaa tgggcgctca agtctatgga gctggtactg
    16981 aaacaatgcg tattgaaggc gtggatcatt tacatgcagt caaccactca atcgtacaag
    17041 atcgtatcga agcaggtacc tttatggttg ctgctgcaat gacacaaggc aatgtgctga
    17101 ttgcagatgc tatctctgaa cataactgcc cattgatttc taaattgatc gaaatgggtg
    17161 cagaaatcat tgaagaagaa ggcggagtcc gtgtcatcgg accaaaacat atcttaccta
    17221 cagatgtaaa aacgatgcct catcctggtt tccctacaga tatgcaagct caaatgacag
    17281 ctatccaatt agttgcagaa ggtacaagtg tggtgactga aacagtgttt gaaaatcgtt
    17341 tccaacattt agaagagatg cgccgtatga acgctcatgt caaaatcgac ggaaatgtag
    17401 caatcatgga tggaaaccat gaattgcaag gtgcagaagt atatgcaaca gacttgcggg
    17461 cagcagcagc attagtttta gctggcttga aagcaaatgg aatcacacgt gtgcgtaact
    17521 tgaattatct agaccgtgga tattataatt tccatatcaa actacagcaa ttaggtgcag
    17581 acgtcgaacg tgtagacatg gatcaaactt ctgctgaaaa aacagcacaa acgattgctt
    17641 aaggaagtgg ctgaatgagt aaccaacgat atatcttatt aactttgata aagattttag
    17701 tggtgatctt attgcttatc cttctttttg tggccggaac gatgatcgga tatggtgtca
    17761 tcggtggcgg caatccattt aaagtattcc agccaagttt gtggattcat attcgagact
    17821 tttttcattg ataaataaga atcacagtgg ttctagtcga tatgaagtga gccatgaagc
    17881 agaacatgat aaaagaaaac agaagggaac gttgacgtta gtcgcgatcc ctttttttag
    17941 taaaagaaaa gaaggaatct aattgatgaa gaagatattg atttatttag ttagaggata
    18001 tcagcgcttt atttcgcctg catttccacc tagctgccgt tattacccaa cctgttccaa
    18061 ttatatgata aaagcaattc aaacccatgg tgcgctaaaa gggacggtaa tggggactgc
    18121 acggatctta cgctgtcatc cttttgtcaa aggcggtatc gattatgtac cattgacatt
    18181 ccgattaacg cgaaataaga aagataaaaa agaaccagat tataaaaagg ttgtgaaaaa
    18241 tacgggtagc actgagcgat aaagaaaaag aggaaattta ttgtcaaagt aacaactccg
    18301 caactactta tatgggggac aaaaaatgat cgaagaacta aacaagaaag atttaccatg
    18361 gtccttgtta ttagatgcag atcctgataa agaaaaagtt caagtatatg tttccagagg
    18421 gagtggctgg atatggaaag aaaaagaaaa aacaataggt gtactgatct atgtggcaag
    18481 ggaaaaagaa tacgaaatcg tcaatgtagc agtaacccca acgtatcaag gaaaggggat
    18541 tggcggaaaa ttacttgaga cagcttttca gaagctttca cagctagctt caaaccaaac
    18601 tcggatcatt atacgtactg gcactactag tagcgctgcg ttacacctct atcaaaaaat
    18661 gggctatgtg gagattggtc gagtcaaaga ctattttatc catcattaat ctgagcccat
    18721 ttttgaaaat ggagatcaat taagggatca agtgatttta gcaattcact tacctaaaaa
    18781 tagctttaac taataaactt tcaattcgag aaaatgcttt caaatgctaa atagatacat
    18841 tacaatagct ttagcaaaca aaaaggagaa tatttttatg ggaatattag tttttgattt
    18901 tggtggatcg gctgtcaaat atggttgttg ggatggcaaa gagattaaag gtaagggaca
    18961 atttgcaacg cctgaatctt gggaagaaat gaaaacgcaa ttatttcaag tttataaaaa
    19021 aatactcgtt tcttttgaag tcgaaggaat tggaatcagc tctcctggag tagtgaataa
    19081 tgagaaacag gtgattgagg gaatcagtgc gattccttat attcatggat ttaatatttt
    19141 ccgagatttg gaaactctgt ttcaactccc agtaacgatt gaaaatgacg ccaactgtgc
    19201 cggaatggct gaattttatg aaggtgctgc ccgtgattat caagatgttg cttttgttgt
    19261 ggcaggaact gggattggcg gggcgttgtt cacgaaagga caaataaata aaggggcaca
    19321 tctttacggt ggagaatttg ggttgatgtt cttagatggc gataagacat tcagtaaact
    19381 tggtacagcg gtacagatgg cttggcgtta ttgtgaacgc aaaggtctcg ataaaaatgc
    19441 ttataccgga aaagatgtct ttgaattagc agaaactgga gatgcaatag caaaagaaga
    19501 agttgagagt ttttatacgt atcttacaaa gggattattc agtattcaat tttcgtttga
    19561 tccagaagtg atcgtattag gcggcggggt ttctgcaaaa gaagggctca ttgatgagat
    19621 caaaagccga atgaagaagc tgacagaaca attcgatctg catgatttcg aaccgcagat
    19681 tttattatgt gagtacagaa acgatgctaa tcttgtaggt gcagcagcaa actatctcgc
    19741 tgtacgtcaa ggagagaatt aagagcttta gagaaggtgc agcttgcata aaagaagaga
    19801 atgaaatgaa taggagattt ttacctaagg aatgttttat ttgctgcagt atgataaaat
    19861 atctgagagg tgaaaatgat gtcaaaaaaa aataaagata ttgaagtgcg tatagaagaa
    19921 gtgaaaaaag atatcaaagg taagaattat gaagtcactc agttatttat agggaaaaaa
    19981 atgattggtg agatcttagc ctatgggcca aaagaatatg aaattttctt tggtgaagaa
    20041 gattttggaa aagaaaaaag tcttgaaaat gcgatagaaa cagtgattcg acactggaat
    20101 ctgcacgaat aaaaaaatat caaaaaaact ttcaataaag ggttgcaaaa atctggaaaa
    20161 ttaggtatta taactaagtc aggttgatac aaacctttcg gaggagtagc gaagtggcta
    20221 aacgcgacgg actgtaaatc cgttccttag ggttcagtgg ttcgaatcca ctctcctcca
    20281 tttcattggg gtatagccaa gcggtaaggc aagggacttt gactccctca tgcgttggtt
    20341 cgaatccagc taccccagta
//
LOCUS       DACDLM010000053        19813 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.053, whole genome shotgun sequence.
ACCESSION   DACDLM010000053 DACDLM010000000
VERSION     DACDLM010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19813
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.053"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            252..527
                     /locus_tag="IV356_001966"
     CDS             252..527
                     /locus_tag="IV356_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015635.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            540..2618
                     /locus_tag="IV356_001967"
     CDS             540..2618
                     /locus_tag="IV356_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAP9015636.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            2778..4664
                     /locus_tag="IV356_001968"
     CDS             2778..4664
                     /locus_tag="IV356_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP9015637.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            4676..5623
                     /locus_tag="IV356_001969"
     CDS             4676..5623
                     /locus_tag="IV356_001969"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAP9015638.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            5643..6170
                     /locus_tag="IV356_001970"
     CDS             5643..6170
                     /locus_tag="IV356_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP9015639.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(6233..6886)
                     /locus_tag="IV356_001971"
     CDS             complement(6233..6886)
                     /locus_tag="IV356_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAP9015640.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            7018..7860
                     /locus_tag="IV356_001972"
     CDS             7018..7860
                     /locus_tag="IV356_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP9015641.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            8018..8914
                     /locus_tag="IV356_001973"
     CDS             8018..8914
                     /locus_tag="IV356_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAP9015642.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            8917..9630
                     /locus_tag="IV356_001974"
     CDS             8917..9630
                     /locus_tag="IV356_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HAP9015643.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            9650..10168
                     /gene="msrA"
                     /locus_tag="IV356_001975"
     CDS             9650..10168
                     /gene="msrA"
                     /locus_tag="IV356_001975"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAP9015644.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            10165..10392
                     /locus_tag="IV356_001976"
     CDS             10165..10392
                     /locus_tag="IV356_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HAP9015645.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            10544..11095
                     /gene="lepB"
                     /locus_tag="IV356_001977"
     CDS             10544..11095
                     /gene="lepB"
                     /locus_tag="IV356_001977"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAP9015646.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(11178..11720)
                     /locus_tag="IV356_001978"
     CDS             complement(11178..11720)
                     /locus_tag="IV356_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAP9015647.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(11957..12355)
                     /locus_tag="IV356_001979"
     CDS             complement(11957..12355)
                     /locus_tag="IV356_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAP9015648.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            12615..13475
                     /gene="ylqF"
                     /locus_tag="IV356_001980"
     CDS             12615..13475
                     /gene="ylqF"
                     /locus_tag="IV356_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HAP9015649.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            13468..14235
                     /locus_tag="IV356_001981"
     CDS             13468..14235
                     /locus_tag="IV356_001981"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HAP9015650.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            14291..15148
                     /gene="dprA"
                     /locus_tag="IV356_001982"
     CDS             14291..15148
                     /gene="dprA"
                     /locus_tag="IV356_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HAP9015651.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            15270..17348
                     /gene="topA"
                     /locus_tag="IV356_001983"
     CDS             15270..17348
                     /gene="topA"
                     /locus_tag="IV356_001983"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HAP9015652.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            17317..18693
                     /gene="trmFO"
                     /locus_tag="IV356_001984"
     CDS             17317..18693
                     /gene="trmFO"
                     /locus_tag="IV356_001984"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HAP9015653.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            18891..19796
                     /gene="xerC"
                     /locus_tag="IV356_001985"
     CDS             18891..19796
                     /gene="xerC"
                     /locus_tag="IV356_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HAP9015654.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
BASE COUNT         6875 a         3415 c         4119 g         5404 t
ORIGIN      
        1 gtcgcagccc catttttttg ttgtgataaa agaacaagaa aggcaggaat gggaaagtaa
       61 acatcctttt gtcagaaact tttatctttc ttaagtttta cttgatatct gatactattt
      121 ggaatagaat gaggcgttga aaaatttatg gaaatttcta actagcaata aacgatgaaa
      181 caatgaaata tttttcatcc aaaaagaact ttgctataat gatggaagtt tgtgtatagg
      241 agatctggaa aatgagagag agttttgaac aacaaaaaaa actgttgcat gatcgctatg
      301 gcgccctttc gatggatgac cgccgtcaaa tactttgtaa gttgcgtaaa agaaatatat
      361 tgatgtatcg tcagttggaa cgtctgaaac atgatctgct tcgtttggag tcaaaacgtg
      421 tacagtgtga attagagggg aaccaaacac aggttgaagt agtcgaaacc aaaattttaa
      481 agaaaaaaga acaattttta aaaatgctta cacaaaataa aaaataaagg ggatggacga
      541 tggaatttgc tgagttagtt attgtatttg cagtaacgat caccttatcg aacatagcta
      601 gccgcatttt gccaatgatt ccagctccac tgatccaaat tttccttgga gtggtattag
      661 gtctgacaga gtggggacaa tcaatcgatt ttgaacctga attgttctta gttatgatta
      721 ttgcaccatt gttatttaga gaaggagaaa aagcagatat ttcttcgatt ctcaaaaatt
      781 tcgggacaat tttgttcttg gcatttggag gagtcatttt gacccttgtc ggggtaggtg
      841 cgacgttatc attcctgttg ccaagtgtcc cacttgctgc ctgctttgct tttggagcag
      901 cgttaggtcc gacagatgcg gtagcagtca gttctctttc tggacgagtg aatatcccta
      961 aaaaggcgat gcatattttg gaaggagaag gtcttttgaa tgatgcatct ggtgttactg
     1021 ccttccagtt tgctcttggt gcgctgatca ccggatcttt ttcagcagta aacgcgggga
     1081 tgagtctagt agtttctagt attgggggag ctttgatcgg ctttttgctt gtctggttca
     1141 aacaaaaaat aattcatttg atcgaaaaag catcagcaca agatgtcaca gggtatctgc
     1201 tgatcgaact tttgcttcct tttctagcct atgtattggc agaggcattt gatgtatctg
     1261 gaatcattgc tgcagtggca gcaggtattc tccaagcttc tggttttagg aaaatctctg
     1321 tgtttgatgc agaattgtcg agcttgtccc acagtacatg gacaactatt gcttttacac
     1381 tgaatgcatt agtatttata tttttaggaa tcgaattgac gcaagtgttc tcgccagtat
     1441 ggggagacgg tttatatcca aacggtcttt tattagcgat tatcgtatta atctctgtca
     1501 tgctttttgt gatcagattc atttctatca gtctttttta tgtattcaaa gatggcagta
     1561 aaaagttcaa aaaacagttg aacgagatct tgatcttaac atttggcggt gtaaagggaa
     1621 cagtcagttt ggctacgatt tttattttgc cattttcaat caataatatg atgttttacc
     1681 agcggtcttt gcttttgttt ctgacggcgg gtgtcatctt agtgactttg gtcataggga
     1741 tcattgtctt gcctatgctg acggaaacag aggaagcgaa aagcacggat ttgaatgctt
     1801 tgatgatttt agaagaggtc gttgaagttt tgcgaaaaga aataaaggaa attgatcgta
     1861 atacaaaaga atttttagcc actgaagcag tgatagaaaa ttatcaagaa cggatacgtg
     1921 atctgtactt ggaagattta accgatgatg aaaagcaaga agtacaagaa atacaagcac
     1981 tgattttgtc gatcgaacgg gatggattgg atgaaagtta tcgttcgggc aagctttctt
     2041 ctaatggtta tcgtttttac tcccgttttc tttctcgatt cgaacattct atcacaagcc
     2101 agattttgtc ttttatcggc ttttggttca ttgttgtccg taggttaatg cgaatcgttc
     2161 tccatccgaa aatgttttgg caaagaagat atgctgatcg tcagacattt attagtgatg
     2221 aagatatcca agaaatcaga gagacatatc aaaaaaatac tcagttgatt attgaaagtt
     2281 tagataactt gactgatatt tatgatgaaa cgatggttca attttttatc cagcaacgca
     2341 aacttgaagg aataaaaatg aactcgggga atttgatttc ttcgtggatg atccagcaag
     2401 atagtctgtt tacgaaaaaa atgctaagag gttattatct tgaaagaaaa atcattgatg
     2461 aatacgaagt tgctgaaaaa atcacgacgt tttctgcgaa cagctatcgc aggaatatca
     2521 atttgttaga atcttatacg atgaacaaac catctgataa cttttctttc cgatttgcgt
     2581 ttcgagcaaa gtcaaaaaaa acgagtccaa taaaataaaa aggtaaaaat tttcaagttt
     2641 tataaaaaac aaaacatatc agaacaggat cgaatcggtc ctgttctttt tttgagaaca
     2701 caaaaagaac aaataccaaa aaaattttcc tgaagttcac tatttttatg atacaatatc
     2761 caagataagg agggaacatg ttgaaagaat taaaagtaac tgacctcaaa aaaacttatg
     2821 gtgaaaaaga tttgtttgac cagatttctt ttttggtcca cgaaaaagac cgtatcgggt
     2881 tgattgggac gaacgggacg ggtaaaacaa gtctcttaaa tattattgcc ggtatcgata
     2941 gcagcgacgg tgatcggcaa acagtgtttt atccaactga ttaccgtatt ggttatcttt
     3001 ctcaagcagc tgaattttcc gatgaattaa ctgttctcca agcagtcttt caaggaaaca
     3061 gccccttgat ccaaactgtt cgagcatatg aggaagcatt gatcgaacta ggggaaaacg
     3121 gagaagaccc tgatgtgcaa aaacgttatg ctaaagcaga agaacaaatg aataaagaag
     3181 atgcttggac tacagatacc aacgcaaaga ttattttgca aaaattagga atcagtgaat
     3241 tagataaaaa aatcagtact ttatcaggtg gtcagaaaaa acgagttagt ctggcgcaag
     3301 tgttgattga tgaacccgat ttactattac tagacgaacc aacaaaccat ttagattatg
     3361 aagcgatcga gtggttggaa aactatttga aacaataccg tggcgcacta ttgatggtta
     3421 cccacgatcg ttattttcta gatagagtag caaaccgaat cttcgaactt tcatttggaa
     3481 aattatacga gtataaagga aattatgaag cttacgtctt agaaaaagca gaacgtgatc
     3541 gtgtagaagt agaacaagaa gaaaagcgca agcggcttta taaacaggaa ttagcttgga
     3601 tgagggctgg cgtacaggca cgtggcacca agcagcaagc acggatcaac cgtttcgaag
     3661 atctaaagga gaacttgtac caagtaaacc aagaagatga tttagagctg aacctagcga
     3721 cacaacgttt agggaaaaaa gtactggaaa tcaaagatgg cagttaccgt ataaatgacc
     3781 aaacactgct agaacattta gatttattga ttcaatctcg ggaaagacta ggtattactg
     3841 gtaaaaatgg tgcgggaaaa tcgacattgc ttaatattct agctggcaga attcccctgg
     3901 atagcggtac aatgtctatc ggtgaaacgg ttcatcttgc gtattataca caagaaaatg
     3961 aagaaatggc accagataaa cggatgattg cttacttaca agaagctgct gaagaagcaa
     4021 aaacagcaga tggcagtcaa atcggagtag cagaattact tgaacgattt ttatttccaa
     4081 gatttatgca tgggacactg ataggcaaac tttcaggcgg agaaaaacgc cggttatttt
     4141 tgttgaaact gctgattcag caacctaatg ttttattatt ggatgaaccg accaatgatt
     4201 tggacatagc aacattgacg attttggaag attattttag aagttttcca ggtgctgtga
     4261 tcactgtttc ccatgaccgt tatttcttgg acaaggtagc agataagtta ttagtattcc
     4321 aaggaaacgg aaaacaagaa ctttattacg gaaacatgtc cagttattta ctgaagcaaa
     4381 aagagaccca gcagcctgct gaaaaagcga aaccaaaaat acagagcaag gaacctgctg
     4441 aaaagaagaa attatcttac atggaacaaa aagaatggga aacgattgaa gatgagattg
     4501 cagaacttga agaaaaaatc tcattgctcc aagaagagat gaatcatcaa ggagataatt
     4561 tcactcgatt acaagaattg caaaacgacg tatctgaaac agaagcacaa cttgaagaaa
     4621 aaatggcacg gtgggaatac ttgagtgaat gggtagaaga ttaggaggaa aaaggatgga
     4681 acaagcgtat cttgacttag gaagaaaatt gttggaagaa gggcatcgta aagaagacag
     4741 aacaggcaca ggcacattaa gcttattcgg ataccaaatg cggtttgatc tgcaaaaagg
     4801 gtttcctttg ttaacaacga aacgagtacc ttttggattg atcaaaagcg aattgctttg
     4861 gtttttaaaa ggagatacga atatccgcta tctattacaa aataaaaacc atatttggga
     4921 tgaatgggca tttgaacgct acatcaaaag tccagactat aatggaccag atatgactga
     4981 ttttggccat agatgtttga cagatcctga attcaatgaa gaatataaaa agcagagcaa
     5041 gcttttttgc gagaagatcc taaccgatga ttcctttgct gaaacatacg gcgatcttgg
     5101 acacatctac ggctatcaat ggcgtcactg ggaaacaaaa gacggtggct ttatcgatca
     5161 aatcaaacaa gtgatcgaag caatcaaaaa gactcctgat tctagaagat tgatcgtttc
     5221 tgcatggaat ccggaagatg ttcctagcat ggctttgcct ccttgtcata cgatgtttca
     5281 attttatgtt caagagggac ggctaagctg ccaattgtat caacgcagtg gggatgtgtt
     5341 tctaggcgtt ccgttcaaca ttgcaagtta tgcgttgctg actcacctaa ttgcacatga
     5401 aacaggttta gcggttggcg aatttgttca cacattagga gatgctcatc tttatatcaa
     5461 tcatatcgaa caaatgaaag aacaattgag ccgagaaata cgcgcatttc cgactttagt
     5521 tttgaatcag gaaaagcagt cagtatttga ttttgagatg gaagatatcc aattagaagg
     5581 atatgaccca catccggcga tcaaagctcc tatcgctgtt tagaatcaga aaggatgaga
     5641 aaatgttagc tgcaatttgg gcacaggatg aaaacggatt gattggaaaa gaagaccgtc
     5701 ttccttggcg tttgccaaat gatctgaaat tcttcaaaca aatgacagaa gcaaatacac
     5761 tagtgatggg acgaaaaaca ttcgaaggga tgggtagccg tccgttgccg aatcgtcaga
     5821 cgattgtttt gacgagagat tcttcctata aagcagaagg cgtgcatgtc atgcatagtg
     5881 tggaagacgt gcttgctctg gaaaaagaaa cagacggtat ctttttcatc gctggagggt
     5941 cagctgttta tcaagaattt ctgccatttt gtacgatatt ataccgtaca gtcatccatc
     6001 atgtattcga tggagatgct tattttccac ctgttgactg gtctgattgg tcactgatca
     6061 atactagtca aggagaaatg gatgaaaaaa atcgttatcc gcatcaattt gaaacgtatc
     6121 agcgtaatga gaatcctgta aaaagcggga caggcgaatt gacgatataa aaaagctatg
     6181 gatagactag ctgttattta gagctgtccc atccatagct ttattttttt tattaagtaa
     6241 agaataaaac agagaagtac ataaaacctg cacctaacat aacaaacaaa tgccaaacaa
     6301 catgcatata gcggatagaa ttcaagctat aaaagaatgc gcctatcgtg taagaaagcc
     6361 cgcctgctac catcaaaata acaccagtca ttccaagaga gtgataaaga ggaacagcag
     6421 ccacgacaca gagccacccc ataaaaatat agatgatcgt agatactttt gatactctct
     6481 cccgtttatg caacgtcaac gctttatata taatgccaag aatcgcaaac aaccagatta
     6541 atacaaataa agtccaacct agccatcctc ggatactcag caaacaaaaa ggagtataac
     6601 ttcctgcaat caaaagaaaa atcgaactat gatcgaatac ttggaacacc ttttttgctt
     6661 ttgtaaaaat caatgaatga aacaaagtag acgttaaaaa taaaagaatc atcatcgatc
     6721 catagatagc ataagagaca atatggaggg aggaatgcaa gtgggcacct tttactaaaa
     6781 gaaccactag tcccgcgata ctcaatccag tcccaattcc atgggtgact gcattaaaca
     6841 cttcatttaa tatttcatac gttcgattaa atttcgtttt ttccatgaaa acggctcctt
     6901 tactaggtgt aattaatgaa aaatcattat ttgtctgtta tactaaaaat agaaattgtc
     6961 ttacatgtag tttaacatga ataaggcatc ttgttaaaga aagagagaga gaaaataatg
     7021 acaaatgtaa aaatcgtaac agattcttca tgtacgatgg aaaaaaatgt acgcgatgct
     7081 ttaggcattc gtgtcatgcc gctatccatc atgatcgacg gaacagtata tcccgatgat
     7141 gaccaactag acggcgaaag atttatggaa atgatggcga aagcaaaaaa tctgcccaaa
     7201 acaagccaac caccaattgg agaattcatc tcgatgtatg atgagctagg agaagacggc
     7261 agtgaagtga tttcgatcca tatgacaaaa ggcttgagtg gaacagtaga agcagcaaga
     7321 caagccagta atctaacaaa aacgaaagta acggttatcg acagtgatac cactgaccaa
     7381 ggattatctt ttcaggtaat tcgagcagct gaattagcaa aagaaggtaa aacagtagag
     7441 aaaatccttg aagaagtcaa aaaagtacaa gacaatacaa aattatacat cggaatatcc
     7501 acactagata acttggtaaa aggtggaaga atcagccgaa caactggttt gctgtctagt
     7561 gttttgaaca tacgcgtggt gatgaatttc gcccattctg aattaatccc tgtaactaag
     7621 gggcgaggaa agaaaacgtt cgataaatgg tttaataatt tgaaaaatga actgaaagaa
     7681 ttgccaaatg tgcgacaaat cggtatttca catgcggatg caaaagaatt ggcgcaagaa
     7741 ttcaaagagg gtttgcaaga attattcccg gacatgcata tccctgtact gcatacgaat
     7801 ccggttatcg ctacgcatac tggtaaagac gcgtttgcaa tcatgtatta tgtagattag
     7861 tcgaaaagag gataagccct cagcctgaaa ggcttgcagc ttattctctt tttctttata
     7921 aaattaggaa aataattgtt ttcttttttc ataaagacta cctttttgat aaaatttttg
     7981 ataacattag aaccaatcga atacaagagg tgaaaaaatg aaattaacga aacgacattt
     8041 gatcctcgtt ttgttcccat tattaattgc gatcatcatc tatgcaggtt tagctgcttc
     8101 tataccgaaa gctggcccac taatgaaacc agtaactact gtgagagaag atccaaataa
     8161 aaaagaaaaa cttcactaca tagctatcgg agattcgctg actgaaggag taggagatca
     8221 aaccaagcaa ggaggattcg ttccccttgt cgcaaatgat ctaaaagacc gttataattt
     8281 gaccgcggtt gaaacagaaa actatggtgt aaatggtgaa cgaagtgacc agatcttaaa
     8341 gcgagtaaaa acaaaagaag aaattcgaaa caatatcaaa acagctgatt ttatcacact
     8401 gactgttggc ggtaatgatt tgatgaaagt tatccaaaat aatttattcg ggttaacggt
     8461 caattccttt aaaaagccac tgaaaaacta tcaggaaaat gtcacagaac tattggaaga
     8521 atttcgatcc ctcaataaaa ccgcacctat ttacatttta ggcatctaca atccatttta
     8581 tttgaacttt cctgagatca ctgacatgca gacaattgtt aacaattgga acaaaggaac
     8641 agaaacggtg acaaaaaaaa tgccgaactg ctactttatc ccaatcaatg atttgcttta
     8701 tcaaggattg aatcaggaag taggtgtcac agaagaagga acagatcaaa caactagcac
     8761 gacagaaaat ctaaatggca tcaaaaataa tgtgctctat gaagaagatc atttccatcc
     8821 aaataattta ggttatcaat tgatggcaaa tgcagtgaga gatcagctga tcgagacaca
     8881 aaaccaatgg ttagagaagg aggatgatca ataaacatga aaacaagatc tgacgtatct
     8941 tcaaacaaaa caaagaaaac aaattactgg aaattcgcct tccttatcct tcttggggta
     9001 gtacttggtt cgaccgtatt tttaggcagc cgtatttttg ctaatcggga accagaactc
     9061 ccagaaatac cagctcttac ggaaagacaa ggagatcctg tcttaacgat caattcaaat
     9121 aaagaaaaag tcaatcaaat catcagcttt ttccttagtg agtatcaaaa agatagtgat
     9181 attgaatata aattttattt ggaaaatgaa gcactactca atggtacttt cgaagtacta
     9241 ggttttccta tcgatttcta tttatatttt gatccgtatg tgatggaaaa cggaaatgtc
     9301 caactaaaag ctagaagtct ttctatcgga acattgagtt tgccaatcaa agatgtgatg
     9361 aatatgatca agagaaacta taaattacca gattggatcg aagtcaatac agatgatctg
     9421 actatcatgc ttaggttgga tcaattccga atgcaaaacg ggatgtatat taaagcagat
     9481 aaaatcgact tagtaaatga tgacattcgg tttagtctat atttgccaaa agatacctct
     9541 gatgcttcaa acaactcaaa taccaacaaa actagcacca gcagtactga aagcaagaca
     9601 aaagaaaata aaaaatcatc ggatgagtag tattagaggg ggaatcataa tggaacgagc
     9661 aatatttgca ggaggctgct tctggtgtat gatccagcct ttcgacacgc ttcctggtat
     9721 ccatacagtg atgtcaggat atactggagg gcatgtacca gatccgactt atgaacaagt
     9781 aaaaagccaa acgactggac atacagaagc agtggagatt atctatgatc caacattgat
     9841 ttcatatgaa caattagtag aactttactg gcagcaaact gatccaactg acgctttcgg
     9901 acaattcgag gatcgcggtg acaattatcg cccggtgatc ttttatttga cagaagaaca
     9961 gcggatcatt gctgaaaaaa gtaagaaaca gttagctgaa agtggacgtt tcgaacagcc
    10021 aatcgttaca aaaatcgaac cagcccaacc attttatcta gcagaagaag accatcaaga
    10081 gtattataaa aagcatcctg aaaattttaa aagaaaccat gcacgccggg ctgcctttat
    10141 cgaagaaaat tggaggaacg aagggtgaat cgaagctttt ttcattattt aatgacactg
    10201 cgaggcggtg gcacacatga tgctttatct gttttcgcta cagaagccgg taaagacatc
    10261 caatttccta agcacagctc tagctacgaa gaaatttcta attatctgga actgaatgtc
    10321 gactatttgc cgtccatgga tatctttgac gaagcatggg aaaaatattt agaaaataat
    10381 catgacatat aagagatagt tttgtacttt atgatcaaaa aagttttttg tccaatagcc
    10441 taattgaaag aattattttt atttcagcta tctagtcgca tttttttgat atttttctta
    10501 taataaagaa agaatgaaaa aaagagggat ggattgatag agattgacaa aaaaacaacg
    10561 ctatattaat cgcttctggc ttgtattcaa atacttactt gtttctgtat tccttgcgtt
    10621 catgttgcgg ggatttttat tcatcccggt accagtggaa ggcaattcaa tggaaaacgt
    10681 gttgaagcaa ggtgatatgg ttgtgatgga aaaattttcg gagatcagac gatttgatat
    10741 tgttgttttt caattagcag atggcacgat ttatatcaaa cgagtaatcg gtcttccagg
    10801 agaaaatgtc agctaccaaa atgatcaatt gaagatcaat gggaaagtag ttaaggaacc
    10861 ttatctaact aaaaacctga aatcagatca tgcaaatgca tcctatacga cggactttac
    10921 actacaagag ctaacgggac aatccaagct tccggaagat aattattttg tacttggaga
    10981 taatcgaaga gtttcaaaag atagtcgttc gtttggcacg atcaataaaa ctgatattct
    11041 aggtaaagca agatttgtct attatccact tgatgaaata aaatggatcc agtgagaaac
    11101 aataaagcgt gcagtctgtt gagactgcac gctttattgt ttaatccaaa atcagtttac
    11161 taccttagta cgtaaaatca aacagctcgt ttaaacactt ttctagcctc taaagttttg
    11221 ataaatgaat aaacaaccat tatttgaata gggatttgga tcatattcct gatgaatcta
    11281 cctagaaaaa ttactttgaa atctgcacca aacaaaacag acatcagcca agaattgata
    11341 aaaaggctga ctgggatcat aatcaataat tgggcagcga tgacggaagg caggtttatc
    11401 tttttatgat ataaaaataa gccattaata aatccaccaa ggaaagccgt gataagaaaa
    11461 gcagcttgaa acgttcctga accaaatatc gtgaaattta aagtgttcga caacatttca
    11521 agcaaaccag cccagatcgg tccatataga taacccataa gcgccatact taaaaatccg
    11581 aatgtgattt gaaaataagc aggaccaatc gctatcttgt ataagatgac atcaagggct
    11641 aataaaagag cagaggtcga caacaatctt gcattcattt cgggcaatct aaaaacgtct
    11701 tttgcaatca aagtgttcaa aatattctct cctttgtcag ttaataataa aaggatacca
    11761 taaaatcacc aatgtgtcat gacacattgg tgatttacat acactggcat ctaacaatta
    11821 aaaaaagggt gagaagactg cttttataaa ctgtaaaaaa gagattgtac gaataaaaaa
    11881 aatagaggcg gagaatactt atcgtatcat ccgcctttgt ttttttgtta taaaaaacgt
    11941 cagattagtt atctgcttac atcttcatcc atacgggttc taatgtattt ccgtctagat
    12001 cttggacttc taatgaaaac atttcttctt caggcattcc catatctact tcgtggaaag
    12061 taccaccatt ttcttttgca atttgagcaa atttttttac ttcatccgca ttttcaacac
    12121 taaacgaaat caaagcacca cttgtttttt tattatcagc tatttcttta tcttttataa
    12181 attttttata aaaatcatga gagagaagca ttatccaaaa agtgtcatcc cataccattg
    12241 aaccagcttc ttcagtagaa aattcttcat tttttttaaa acccagcttt tcataaaaag
    12301 caacggaacg attgacatca gcaacaggaa aattaacaaa aaccatacta ttcatttgtt
    12361 tcgtctcctt tctgttttgt tcgtctatca tctcttattt aggaaacgct gtcaaaaatt
    12421 tagattcata tatagaaacc aaaataaaaa tttgcatcat caaaaaagtg aagatgtgat
    12481 agaatgagga ctggttcact ttcacttaac taatagatgg aatttcttta taataaaaaa
    12541 gtgaatttat attgaaaaag aaaaaaacaa gtaaagccgg ggaatattcc ggtatgaaag
    12601 gaatggagag aacaatgacc atccaatggt ttccgggaca tatggcaaaa gcccgacgag
    12661 aagtttctga aaaaatgaaa tatgtggaca tcgtatttga attggtagac gcacgattac
    12721 ctttatcttc tcgtaatcca atgctagatc agatcattca gcaaaaacct cgccttgttt
    12781 tattgaataa agcggatctg gcagatccac aacagacaaa gctgtggcaa gaatattttc
    12841 gtaaacaagg ccatcttgca ttagctatca cggcacaaga aagtaaagga attaaaggtc
    12901 tagtacctgc ggctaaagaa gcattgaaag aaaaacgggc aagagatgct gctcggggga
    12961 tcaagcctcg cgctattcgg gcaatggtct taggtattcc aaatgttggg aaatctacgt
    13021 tgatgaatcg actagtaggc aagaaaattg cacagacagg aaataagcct ggcgtaacaa
    13081 aaggtcagca gtggcttcgt ttaggtaatg agttggaatt gttagacaca ccagggattt
    13141 tatggcccaa atttgaagat gaagaaatcg gcaaaaaact agcgctgaca ggcgcgatca
    13201 aagaccagct tgtccattta gatgatttag cgatttacgg attagacttt tttgcccgat
    13261 attattcagg aagaatcagc gatcgttatg gtttatcaat cgagcaagaa gaaaaattgg
    13321 caccggaatt actgatggat attacagcaa aacgtgggta taaagaagac tatgatcgtg
    13381 gcagcgaatt agtcgtgcat gatattcgtc aaggaaaact tggacgatac acactggatc
    13441 gttgcgaaga aatggagcaa aaaagtgatg actgaatcca tccaaagtat caaagaacga
    13501 ttgaaaagca tacagagaat agatgatcct acactagaat cattaagaaa tgatccacgc
    13561 aaaggcgtgc agcaagcact ggcttctttt gaacgacgat tgaaaaagga agcattaatt
    13621 aaggaaaaat atgaagaaat gttttgcttt gaaaagcaag ggtacgcaca aggtcaccaa
    13681 tggattgccg gcattgatga agtaggaaga ggaccattag ctggacctgt cgtggcagct
    13741 gcagttatct tgccgaaaaa tgagatcata ttagggctga atgactccaa acaattatca
    13801 gagaaaaagc gagaacttct ttatcaacaa gttcaagaaa aagccctggc aatcgggatc
    13861 gggatcgttg atcagcagac aatcgatgat gtgaatattt atgaagcaag taaattagcg
    13921 atgatccaag cagtagaaaa attgtccatt gtaccaagct atttgttgat cgatgcgatg
    13981 accttggatt tgcctattca gcaggaaaaa ataatcaaag gggatgcacg atctgtgtcg
    14041 attgctgctg caagtatcat tgctaaagta tatcgagacc aattgatgaa agaatatgac
    14101 gtgctttatc ctggatatgg tttctcgcat aatgcaggtt atggaacaaa ggaacactta
    14161 gaaggacttg aacgacaagg aattacgcca atccatcgta aaagttttgc acctgtaaaa
    14221 aaatatttac aataaaaaac agccgctttt acgtatctta ttagaaagag agacgaaagg
    14281 cggttttatg atgtatcaaa tagaagaaaa tttattgaaa cttgcttata caaaaggaat
    14341 cagtagtcaa ggaaaatggg cacttgctaa ctggatgatg cagtatcctt ataaagaaat
    14401 cggatttgaa gacatcatta agataggtaa aataaccaaa caccgggagc tgtttcgcaa
    14461 aagttggcag gaaattcacg ctaactgggg caaaatccaa tcgaaacagt cgtttatcac
    14521 ttgctttgat cccaaatatc cccctcagct gcttcacttg acctatccgc caattgtact
    14581 gttttataat ggtgatctat ctttactttc ttgtaacatg ttaagcgttg ttggtggaag
    14641 acacacttct gctttagcca aaaaaacagt ttattattta ctaaaaccag tgatagaagc
    14701 tggatatgtg atcgtcagtg gctgcgcgaa agggatagat acatacggtc accaagcagc
    14761 aatctctcat ggtggacgga caatcgcagt cattggaaca gggatagagc aagtctatcc
    14821 tgctgaaaat cgtgacttgc aagaggtgat tgcaaatgat catcttcttt tgagtgaata
    14881 tcctcctcaa tccggcccga aaaagcattg ttttccaatg agaaatcgga ttatcgcagc
    14941 tttgtctaaa ggaacatgtg tctttgaagc caagaaaaaa agcggctctc tgataacagc
    15001 acagcaagca ttggatcttg gaagaacagt tttttctgtt ccaggaaata ttttaacaga
    15061 acattctacc ggatgtcatc atttgatcca agacggtgca gtttgcacgg tttcgggtga
    15121 agatatcttg gcagaattta aagaataaca ccatactttt catttgcttt tcttgacaaa
    15181 cgttttctga atggatatga ttagctacga tttgtatgaa tcctctttta atagtaggaa
    15241 cacgacaatg gaaaggagtc cattcagtaa tggcgtataa atatttagtg attgtagaat
    15301 cacctgcaaa agccaagaca attgagaaat atcttggacg aaactataaa gtaatggcca
    15361 gtgttggcca tataagagat ttaccgaaaa gtaaaatggg tatcgatttt gaaaacaatt
    15421 atgaacccca ttatatttct atacgcggaa aaggcgatgt catcaaaagc ctgaaagccg
    15481 cagcaaaaaa agctcaaaaa gtttacttgg caagtgaccc ggatagagaa ggagaagcga
    15541 ttgcttggca tttagcgtac ctacttgggt tggatctgaa agaaaaaaat cgggtggtct
    15601 tcaatgaaat cacaaaagac gcagtcaaag cagcttttaa ggaaccaaga acgatcgatg
    15661 tagatttagt agatgcacag caagctcgtc gtaccttaga cagaatcgtt ggttattcga
    15721 tcagtcctat tctctggcgt aaggtcaaga aagggttaag tgcaggacgt gtccaatctg
    15781 tcgctttaaa aattattatt gaccgtgaaa aagagatccg agaatttgtt ccagaagaat
    15841 attggagcat cgacggtaat tttaaaaaag ctcgcaagaa attcaaagca aatttctggg
    15901 gaatcgacgg taagaaaaag aaattaccag atgcacaaag tgtaaaagaa gtcactgcta
    15961 gaattgatgg aacagacttc gaagttaaaa aagtagaaaa gaaagagcgc aaaagaaacc
    16021 ctgcgaatcc tttcactaca agtagcctgc aacaagaagc tgcccgtaag ttaaactttc
    16081 gaacaagaaa aaccatgatg gtagcacagc aattatatga aggaatcact ttgggtaaac
    16141 aaggaacagt cggcttgatt acatacatgc gtactgattc tacccggatt gccgatacag
    16201 caaaagcaga ggccgcagca tttattgaag atacgtatgg aaaagaattt tctagacatg
    16261 atcaccgaaa gatcaaaaat gctcaaggcg cacaagatgc ccatgaagct gtgcgtccaa
    16321 cgagtgtgct tcgtacacca gatgaactca aacaatattt agataaagat caattgaaac
    16381 tttatacatt gatctggtca cgttttgtgg ctagtcagat gacaccagct attttagata
    16441 caatgaaagt gacattagaa caaaatggtg tcatcttcat tgcgaacggt tcaaaaatca
    16501 aattcaaagg attcatgcaa gtgtatgtgg aaggtagaga tgacggcaaa gaagagaaag
    16561 aaaatattct tccagaactt gaagaaggcg atgtagtcca atctgttgat attgaaccaa
    16621 aacaacattt tactcaacca ccagcacgtt ttagtgaggc tacgttgatt cgtgcactag
    16681 aagaaaacgg ggtagggcga ccttccactt atgcaccaac acttgatacg atccaaagac
    16741 gctactatgt aaaattgaca caaaaaagat ttgagccgac tgaactagga gaaattgtca
    16801 attcattaat ctgtgaattc ttccctcaaa tcgtcgatat ccatttcaca gcagaaatgg
    16861 aaggagattt ggataaaatt gaagaaggca cggaagcgtg ggtcaaagtg gttgatcgtt
    16921 tctataaacc gtttgaaaaa gaactgacga atgcggaaga aaaaatcgaa aaaattcaaa
    16981 tcaaagatga accagcagga ttcgattgtg atgtctgtgg acatccgatg gtgataaaat
    17041 tagggaaata tgggaagttt tatgcttgca gtaattttcc tgattgtcgg aatacgaaac
    17101 caatcgtaaa agaaatcggt gtgacttgcc cagtatgtca tgaaggacaa gtcattgaac
    17161 gaaaatctaa gaaaaacaga ctattctatg gttgttcccg tttcccagaa tgtgaattca
    17221 cttcttggga taaaccagtg ggcagaaatt gtccaaaatg tgacggatat ctggtcgaga
    17281 agaaagtcaa aggcggtaaa caagtagtct gtgtaaatgg agattacgaa gaagacatcc
    17341 aaaaataata gaaaagaggt tctttcattg aaaatggtaa atgttgttgg agcagggctt
    17401 gccggaagtg aagctgcttg gcagatcgca caagcaggag tccctgtccg tttatatgaa
    17461 atgcgtccag tcaaatcgac tgaggcgcat cacacaagta attttgctga actagtatgt
    17521 tccaattcat taagaggaaa cagtttggct aatgcagtag ggttattgaa agaagaaatg
    17581 cgccgattga attcggtagt aatcacttcg gcagatgaaa cagcagtgcc agctggtggt
    17641 gccttagctg ttgaccgcga ttctttttct gaaacaatta cccgaaaagt caaagagcat
    17701 ccattagtaa cagtgataaa cgaagaaatt actgaaatac cggaaggaat caccgtagta
    17761 gcaacaggac ctttgacttc tcatccatta gcagaaagca tcaaagcatt caatggttca
    17821 gatggttttt atttctatga tgcagctgca ccaatcgtag acaaagctac gatcgatatg
    17881 gataaagtat atttgaagtc ccgctatgac aaaggagaag cagcttactt gaactgtccg
    17941 atgacagaag aggaattcaa agctttccat gaggcactaa tcaatgccga agtggcagaa
    18001 cttaaatctt ttgagaaaga aaaatatttt gaaggatgta tgccaattga agtaatggca
    18061 cagcgaggat tcaaaacgat gcttttcgga cctatgaaac cagttggatt ggaagatcct
    18121 aaaactggca aacgtcctta tgctgttatc cagctgcgtc aagacaatgc tgcagcttct
    18181 ttatacaaca tcgtgggctt tcagactcac ttgaaatggg gcgagcaaaa acgtgttttc
    18241 cggatgattc ctgggttaga aaatgctgaa ttcgttcgct atggtgtgat gcaccgaaac
    18301 agctttatga attcgccaga attgctgaaa ccgacttacc aatcaacgaa acgcgaagat
    18361 ctgttctttg caggtcagat gactggtgta gaaggctatg ttgaaagtgc agcgagcgga
    18421 ctacttgctg gaatcaacgc cgcacgctta gcaaaagaaa tggaaccagt cgagtttcca
    18481 caagaaacag ctattggaag tatggcttac tacattactc atgcggaagg aaaacatttc
    18541 caaccgatga atgccaacta tggtctgttt cctgaactgc cagagcgcat tcgagacaaa
    18601 aaagcaagat atgaagcaat tgcacaacga gctttaaaag ctaatgaggc aataaaaaca
    18661 gaattagaaa aaactgcaat cccaaatgag taaggaaact ccatgaagag ggtgagacgg
    18721 atagtctcgc tctttttctt gcgtttttct taagaatttc tcaaacaaaa tgtgaggaat
    18781 tgcgccaatt gtgaacaaac ttagaaatat tggttaaatt ctgacaattt atttgtcttt
    18841 ttataaacgc tgtgctaaat tattctctgg gacaaaagga aggtgagaaa atgacagaag
    18901 ccacgtggga acaaaaattt ttgcgttatt tgattgtcga aagaggatat tcagaaaaaa
    18961 cgaaagaagc atatgaagaa gacattctcc atttcaaaca ttttttggag gaatctggag
    19021 acgctgatct gctgaaggcg gaatatttta cggttcgtgt ctatttgagt gcattagctg
    19081 atcatcgtcc tagctatagc agaaattcta tcagtcgcaa gatagccagc ctacgttcgt
    19141 tttatcagta tcttctcaaa gaagaagtga taaaagaaaa tccattttct tacgttcatc
    19201 tcaaaaagaa aaatttgaga ctgccacgtt ttttttatga aaatgaaatg caagcacttt
    19261 ttgacagcgt agcaggagat agtcctttgg atttgaggaa ccgcgcttta ctggaagtcc
    19321 tttacgggtc aggcatccgt ttaagtgagt gtagcagttt gtcggtatca gacattgatt
    19381 ttgattcaga ggtcatgttg atccatggta aagggaacaa agagagatat gctcctctag
    19441 gttcttttgc tcaagatgct ctgcaagaat atttcaggga aggccgccag gtattgatga
    19501 caaaatatca cgaagagcat gatatcgttt ttgtgaatca tcatggaaaa ccaatcacgc
    19561 ctactggaat tgaatatgtc ttgaatcaaa tgatcaaaaa aagcagtttg gatagtgata
    19621 tccatcctca catgctgcgc catacatttg ctactcattt attaaataat ggggcagatt
    19681 tgcggacagt ccaagaattg ctaggacatg ccaatttatc gactacccag atctatgccc
    19741 atgtaacaaa agaaagttta caaaaaaact atcgttcttt ccatccaaga gcgtaaaaat
    19801 aaggaaaaga aca
//
LOCUS       DACDLM010000054        19342 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.054, whole genome shotgun sequence.
ACCESSION   DACDLM010000054 DACDLM010000000
VERSION     DACDLM010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19342
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.054"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..456)
                     /locus_tag="IV356_001986"
     CDS             complement(<1..456)
                     /locus_tag="IV356_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAP9015655.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEK"
     gene            complement(561..1424)
                     /locus_tag="IV356_001987"
     CDS             complement(561..1424)
                     /locus_tag="IV356_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAP9015656.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(1620..3719)
                     /locus_tag="IV356_001988"
     CDS             complement(1620..3719)
                     /locus_tag="IV356_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAP9015657.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(3939..5048)
                     /gene="rpoD"
                     /locus_tag="IV356_001989"
     CDS             complement(3939..5048)
                     /gene="rpoD"
                     /locus_tag="IV356_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HAP9015658.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(5072..6913)
                     /locus_tag="IV356_001990"
     CDS             complement(5072..6913)
                     /locus_tag="IV356_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HAP9015659.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(7095..9488)
                     /locus_tag="IV356_001991"
     CDS             complement(7095..9488)
                     /locus_tag="IV356_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAP9015660.1"
                     /translation="MFLILEHARLKHVIIFESWRKMEKKKMNGLTQQEVVQKMASGQQ
                     NDYQEDASKSTKQIFSDNILTLFNFLNFGIGICLLFVGAYSNMAYLAIIVVNIVIGIY
                     QEIHARNLVRKLSIVSQSEVLVIRDGKEQSISTKELVLGDLVKIGAGEQIPADLQVIS
                     GRAEANEALLTGESDLIVKETGAELLSGSFLTSGSVMAEVIRVGADNYAVRLTSEAKT
                     HKAIRSELVDSIRKVSKFTSFVIIPLGIILFLEALFIRDASIKISVIASAAALLGMLP
                     KGLVLLISIALTTGVTKLAKKRILVQDMYSIETLAHVDTLCLDKTGTITEGKMSIQRV
                     EALHPLYEKAIPEIMGTYLAESSDNNITMRAMRDYFELSNRYDVTNKVAFSSDRKWGA
                     MEFPELGVVYVGAPERLVEEDRLPDSLKTAQANGYRVLMLGIAPNQQLNEEKPAFVEP
                     VALFEIDDPIRKNAQETLAYLHEEGVDLKVISGDNPFTVSNIARRAGLPNYDAYVDLS
                     QITEEMEVREAAHRYTVFGRVSPQQKKLLVNELKESGRTVAMTGDGVNDVLALREADC
                     SIAMAEGDGATRQIANLVLLDSDFTTLPEVLFEGRRVVNNVTKVSGIFFIKTIYSFIL
                     SIICAVTAIGFPFIPIQITLIDLAIEGYPSFFLSFEQDKRKITYRYLPTALINALPNA
                     LLVVVNIIAVYLLGKTFAWGNAETTTLMYYLLIGISCMAVVKACYPFNPLRIFLAVTT
                     IVGIYVAAMLFHGILEVNLGLGESVGYFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(9595..10455)
                     /locus_tag="IV356_001992"
     CDS             complement(9595..10455)
                     /locus_tag="IV356_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HAP9015661.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(10514..11035)
                     /locus_tag="IV356_001993"
     CDS             complement(10514..11035)
                     /locus_tag="IV356_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HAP9015662.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            11355..12074
                     /locus_tag="IV356_001994"
     CDS             11355..12074
                     /locus_tag="IV356_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP9015663.1"
                     /translation="MKKEKKYAKMPDGSEIYYEKSGQGFPLFLLHGNDGSGRFFSEQV
                     PVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEKIDQADFLGFSDGAN
                     LALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVWLLSLFRPSLRKNLL
                     VIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKTIPKASFVLVKEQGH
                     ELARKDPERFNREVLQFLSET"
     gene            12100..14691
                     /gene="mprF"
                     /locus_tag="IV356_001995"
     CDS             12100..14691
                     /gene="mprF"
                     /locus_tag="IV356_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAP9015664.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(14879..16066)
                     /gene="tuf"
                     /locus_tag="IV356_001996"
     CDS             complement(14879..16066)
                     /gene="tuf"
                     /locus_tag="IV356_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAP9015665.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            16434..16790
                     /locus_tag="IV356_001997"
     CDS             16434..16790
                     /locus_tag="IV356_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAP9015666.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            complement(17031..18035)
                     /locus_tag="IV356_001998"
     CDS             complement(17031..18035)
                     /locus_tag="IV356_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HAP9015667.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            18201..19052
                     /locus_tag="IV356_001999"
     CDS             18201..19052
                     /locus_tag="IV356_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAP9015668.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            19069..19314
                     /locus_tag="IV356_002000"
     CDS             19069..19314
                     /locus_tag="IV356_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015669.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
BASE COUNT         5396 a         3992 c         3383 g         6571 t
ORIGIN      
        1 tttttctttt tcatagcatt cctgacagat tccatggaac gttagccgat gatcttttac
       61 taaaaaatga taacgttctt ctactacttg ctccacttca agtaaaagat cctcttctac
      121 ttcctcgatc gtgccgcagt tcaagcatag taaatgatga tggaaatgtt tggcgccttc
      181 ttttctcaaa tcataacggg ctaatccatc attaaaactt actttatcga caattttcaa
      241 ttctgtcaag atttcaaggg ttcgataaac agtagcaagt ccaatttccg gactcttttt
      301 tttcactaaa aagaagattt cttctgcaga taaatgctct ttctcatttt ccaaaagcac
      361 aagcagagta gcttctcttt gcggtgtcag cttaaacccc gcttcatgta gctgctgttt
      421 tgtttttttc atcgccgaaa tagcattcat gaccatttac tcaaccccaa caatttataa
      481 taattacaaa taaaaaaaga tataacacta tgttaattaa aattattata agctagttaa
      541 gaaaaacatg caagggattc tcaattagat tttttgacta gttttgtcac accgttttct
      601 tgtgtaatca atccttgttt caaaagatta cctaatgcgc gcttaaatgc tcctttgctg
      661 ataccaaaag ctttcatgat ttcttctgga tccgatttat ctgtaaagtt gatttgctga
      721 tctgcagaac gttctaaaat ggttaaaatc atttgtgcat catctgatat agcttcatat
      781 gctcttggct tcaatgaaag attcagtaca ccgtctggtc ggacaccaat cactcgacct
      841 tttatctgct cgcctagacg aggttcatta tatcgttcag aaggatggat aaacccaaga
      901 tagaaatctt ccgttaaaac gtacgtacct gttaatttca agcggtatgc tgttcctatc
      961 acatctttgt ttttcatttc ttctgttcca tatttgctta aagatttgaa tattttttca
     1021 tctgctaaac tgccccaaat acggtctttt gcatcaactc taagggaaat catcaagcga
     1081 tccccttttt taggccatag ctctgtcatt gtcggcaatt catcaagaga tacgacaaag
     1141 tctttatctg gaagaccgat atcgacaaac gcacctaaat cttttcgtgt agcagtaacg
     1201 attccaaaag cgtaatgacc gatacggctt ttaggaattt gtgtagtgat ccgattttca
     1261 tgtttttgat tttggtaacc gaatccttca actgcttcac cgattttgtg ttcaccttct
     1321 gatttgctta agccaaaggt ttgtccgttt ttttggacaa agtagttttt ttcattttca
     1381 tcaataataa tacctgtaaa tatagttgct aataaatcgt tcattttttt ctccctctat
     1441 agtgaaaggt tttcttaata catttctttg ctatcataac ataatgttat ctacttgaat
     1501 agctgagcct tggtttggaa aggtgaaaaa aggagtatga caacagttgt gtcatactcc
     1561 cctttttcga ataaacggtg ttaaacggca ggctcacagc ctctttcatt tgcctaaaat
     1621 taattgctcc catttcctcc gaaccatcca gttttacagt tgatggttac gatgtaaaat
     1681 ggcaaagcac tttctccaat gcctttcatc aatgcagatt ttgttgaagt ggcatataga
     1741 ttataatagc cttccccatt ttcgattctg gctttttcta atctgtaacc tccttcaacg
     1801 atatatccac gttggataca tgtagcaatc actttgcttt ggacacctgg tgcccacgtc
     1861 catgctggat tagatgcatc ggcaatatca cttgctctgg cagatttgat tggctgattc
     1921 gctgagtttg aagaggaagg ggtcgaggat gccgcttctt gctgtgctgc ttgtgcgacc
     1981 gcagcttgtt gagcggcttg agctgcagct gctgcttgag cggcttgttt tgcttgttct
     2041 tcagctgctt ttttcgcttc ttctgctttt ttcttttcct cttcttcttt tttctcttta
     2101 tcagtgagca tcttatctac ttgtttcaat tgttcattca actgagcaga tagatctgta
     2161 tttttcactt tttctactgc ttcttttgcc gtcttgtatt ggtcgcgtgt tgctgaatcc
     2221 actacttttc cgtctttaaa gactatagct gttttttctt tagctgtttg caattcagca
     2281 tattgatttt tagcttctgt ttgtgcttgt tgaatcaatt ttccaaaatc tgtgttatcc
     2341 gtttcgattg cttggatctc tttatctgct ttcaacttga tgtcatctgc tagatgatca
     2401 tcgacgatgg caggtgctat gaaccactca ttcacttttt ggatatctcg gatcttagat
     2461 tggatatctt ggtaagttgt ttctaactct gaatatcctt tttcattctt aagactggat
     2521 aaatcatttt ttagttttga taaatcttga tgaatcatat ctgcacgaat aaattgatgg
     2581 tgatcatctg tataaaaggc agcaagtttc tcatgaagtt cttccatttg ttgctgtctt
     2641 tttgcttctg ctgctacttc ggcttctact ttttgatgat ggtcataata agcccagctt
     2701 cctccaccga gtagaagtac tgctgctaaa acgagataag gtactttttt tgattttttc
     2761 ttttgcgctt tatctggatc tgttttttct aagtttgatt cttgatgtgt tttttcagta
     2821 tctggcacga ttgttattga tttcgcttct gcttcaaaca gcttaggctg gttctcttct
     2881 ttttctattt ttgcttcaag atcagtaccc tctttgctta cagattgatt ttcagcatcg
     2941 gattcactat ttatttcatc gggctctgtt gactttttgt ctgtgttttc gagtatttct
     3001 tttttctctg cttccggcag tttattcgtt ttttcctttt ctaattgttt ttcagtaaat
     3061 acttcagttt tttctgtgat atccgttttt acgtctttta tttttactgt ttctttacct
     3121 gtggcgtttt ctctatcaga gtctttttca gtttcttgtt ccttttctgg ctctactttg
     3181 ttttcctgtg caattttttc actgatcatt ttgagcagct ctttcgcgtg ctcttctttt
     3241 gtatcttcac gatgtgcttt gatataagcg gatagtatcg aattttcttc ctcattatcg
     3301 acgatttctt tcagttcagc tactcttctt ttttgttttg attcaagcgt ttcttcttga
     3361 ttctttcctg attcttccga agtctcatga acagttgctt tcttctgttc atttttctct
     3421 atattagtta cttgatcgtg agcaggtggt tcttcgtctt ctggttctgc tttttcgaat
     3481 aattccatta cagattctag aggtaaatct ttcaattccg accattcgat tggatcgttt
     3541 aattctgtat caggaaagac tgcatcttca gttgatttat cctgcatagc tgcatctgta
     3601 tttgtttctt caattgattc ttttatttgc tgatcttctg cagttatttg atgaccgcag
     3661 tctggacaga tagtattctg ctccattttt ttcgatccgc aatttggaca ttttttcatc
     3721 acttagcgat cggctccttt actaggttta cgctaccatt taatctatca tattctatac
     3781 gtcacgccaa tagcttattt ttaggattta cttaaaaata atgaatgaat ttccttccta
     3841 tagaaaaaaa agcttgagac tgcgtagtct caagcttttt ttcttttaaa ataaaccaaa
     3901 cagttttact gatttctctt ctggtcaata gtccacgctt attctaagaa atcttttaat
     3961 tgttttgaac gagaaggatg gcgcaatttt cttaatgctt tagcctcgat ctgacgaata
     4021 cgttcccgag taacaccaaa tactttccct acttcttcca atgttctcgt ccggccatca
     4081 tctaaaccaa aacgtaagcg aaggacattc tcttcccgat cagtcaatgt atctagtaca
     4141 tcttccaatt gttcttttag taactcataa gctgcgtgtt ctgctggact tgttgcttcc
     4201 tggtcttcta tgaaatcacc taagtgagag tcatcttctt caccgattgg cgtttcaagg
     4261 gaaacaggtt cttgcgcgat tttcaagatt tctcggactt tttctgttgg aagatccatt
     4321 tccgcaccga tttcttctgg cgtaggttct cttccaaggt cttgcagcaa ttgacgttgg
     4381 atacgtatca atttattaat tgtttcaacc atatgaactg gaatacggat cgtacgtgct
     4441 tggtcagcga ttgctcgagt gatggcttga cgaatccacc atgtagcata ggttgaaaac
     4501 ttaaatcctt tgcggtagtc aaatttttca actgccttca tcagtcccat gtttccttct
     4561 tggatcaagt caaggaactg catgcctcgt cctacataac gtttagcgat acttactact
     4621 aaacgaaggt ttgcttctgc cagacgctgt ttcgcttctt ggtcgccttc ttcgattttc
     4681 aatgctaacg ctacttcttc ttccgcagtt aaaagggaga cacggccaat ttctttcaga
     4741 tacatacgaa ccgggtcatt gatttttaca ccggttggcg cagaaagatc ttctgttttt
     4801 gcttgttcag cttttttctc agcactcttc aagctgtgaa ttgatggatc accattttca
     4861 tccaccacac tgatacctgc gtcttcaatc ttttggatca atttgtccat ttcatctgca
     4921 ttcaaagtga atggtgtagc aagctgattg gataaatcat catatacaac ttgtcgtttg
     4981 ggtttgtttt ctttgatgaa agctgctact gctgcttcat acgttttttt atctgttcca
     5041 tttgccataa aagaaggccc cccttgagta gctatttggc ttgttttaac tgtttcgtta
     5101 aattgatgat ttcaatcgtc aattcaagct caagctgttt gtttccagtt cgtctggctt
     5161 cttgctgcat ttgttttttt aatgttattt catcagctaa gccagatttg ctgatcacat
     5221 ctagcaagtc ttggatttct cgtggcgaac tttcttctgc caccggtaaa tattcgattt
     5281 ccaccaccaa ccgccttaaa ttttcatctt gcaaaaagtc taaaaactct gcaaggttga
     5341 attcataatg ttgtgagaca tatgcatcga ataaaaaata aacttctgca tatgcatcat
     5401 gaataaactg aaattctcgt tcttttaaaa tattacggac agaaacttct ttaaatgcac
     5461 gatataatag aatctgctct gccttttcta cttgcgtcaa aggtctcttt ttccgtgcag
     5521 tttcttgtct cgtaacctga gtgtgttgac tttcctgagg ttcttgacga ttttgctgat
     5581 ttgtccttcg aagatcgcgc agttgttttt gtatcgtctc tctgccgatc tgaaactctg
     5641 ttgacagttg agatagatac atatcttgtt cgattggtga aacaactcgg ctaagttcaa
     5701 ctagtaattc ttcgaggtat tcgatcttgt ctttttcatt atctaaattt ttcccttgtt
     5761 ttaaataacg tgatttaaaa gtaaagactg tttcgcgccc atgagccact aattcttgga
     5821 aagatgcttc tccatactta cggagatatt catcaggatc aagcttttct ggaacgacta
     5881 cgacagaaag tgctaatcga ctgttttgcc gaagcaattc aatccctcga ttggttgctt
     5941 caaaacctgc gttgtctccg tcatagcaaa agaccaattc tttcgtcagc ttttccattt
     6001 gttggatctg ttgagctgtt agacttgtcc ccatagaagc taatccagtt ttgataccag
     6061 cctgccatgc agcaatcaca tccataaacc cttcgaacaa caaaatttct ccgtttttcc
     6121 ggatatcgct tcttgcttta tcaagattaa ataaaacttg tcttttattg aacagttctg
     6181 tttctggact attcaagtat ttgggctgat ctttttcctg ccctttttca ggtgcaagcc
     6241 agcgtcctga aaaaccgatc gtctggcctt gagaattacg aagtggaaac atcactcttt
     6301 gataaaaacg atcagacata cggccatcat catgcgtgac aaacaatcca gagcgttcta
     6361 acaattcatt tgaaattgat tcattcttga atacttgctg aagaaaagaa cgctcattag
     6421 gtgcaaaacc tatgttgaat tcttcaatta attctaaaga caacccacga ctttgcaaat
     6481 attctaaagc tggctgtcca gcttttgtat gcaatagcat gtgatgatag atttccgctg
     6541 ctttttcatg agcagcaatc agtttccccg tagcagattc aggattttgg acagctatag
     6601 tacgctgacg ccattgatct tctaacggta tctgttcgaa gtctgccact tttaccactg
     6661 cttctggaaa acttagacct tctagttctt gaagaaaagt aaacacgttt ccgcctttac
     6721 cacaaccaaa gcaatgaaaa atctgcttgt cttctgcaac agaaaaagac ggtgtacgtt
     6781 cttcatgaaa aggacacagc cccaagtaat ttttaccaga ctttttcaac tggacatatt
     6841 gtccaatcac ctcaacgata ttcgtttgac tgcgtactgt ttcgataacc tcttgaggaa
     6901 tccgttgagc cattttttca ccccctgctc tattgatatc ttttgggttt aacagaagat
     6961 atttcaggag aataaccggt aaaaaatcgc actaactgaa atcagtgcga ttttaaagga
     7021 cacaattata catgtttgat tgtatcatat ttcattgctt tttcaagtat aacacatttc
     7081 tatctcatta agcatcaatt tgctactctt ttcagtaact gattttgaat atcagccttc
     7141 cagtacaata ctcgaagaac aatatttacg agcatgaata caaagaagta tcctacgctc
     7201 tctcccaacc ctaagtttac ttccaaaatt ccatggaaca gcattgcagc tacatatatc
     7261 cctacgatcg tcgttactgc taggaagatg cgcaatgggt tgaagggata acaagctttt
     7321 acaactgcca tgcaactgat cccaatcagc aagtaataca tcaaagtagt agtttcagca
     7381 tttccccatg cgaatgtttt tccaagtaga tacaccgcaa tgatattcac tactacaagc
     7441 aaggcatttg gtaaagcatt aataagtgct gtaggcaaat aacggtaagt gatttttctt
     7501 ttatcttgtt caaaagataa aaagaaggaa ggataccctt caatcgctaa atcaatcagc
     7561 gtgatttgga tagggataaa cggaaatcca attgctgtaa cggcacatat aatcgataaa
     7621 ataaatgaat aaatcgtttt gataaaaaag atgcctgaga ctttcgtcac attgttgacc
     7681 actcggcgtc cttcaaacag gacttctggc aatgtagtaa aatcagagtc caacaatacc
     7741 agattcgcaa tctgacgtgt tgctccatca ccttctgcca tagcaatgct gcaatctgct
     7801 tctcttaacg ccaaaacatc attcacaccg tcgcctgtca ttgcaaccgt tctgccgctt
     7861 tctttcaatt catttaccag caatttcttt tgctgcggac tcactcgtcc aaaaaccgta
     7921 tagcgatgag cagcttctcg cacttccatt tcttcagtaa tttgagaaag atcgacatac
     7981 gcatcataat tcggtaatcc tgcacgtcta gcgatattgg agacagtaaa aggattgtct
     8041 ccagaaatca ctttcagatc cacaccttcc tcatgaagat aagctagtgt ttcttgagcg
     8101 ttttttcgga ttggatcatc gatttcaaac agagcaaccg gctcaacaaa tgctggtttt
     8161 tcttcgttca attgctgatt tggagcgatc cccaacataa gtacgcgata gccattcgct
     8221 tgggctgttt ttagactgtc cggaagccga tcttcttcca ccaaacgttc aggcgctcct
     8281 acgtacacga ctcccagttc tggaaattcc atcgcgcccc atttgcgatc agaagaaaat
     8341 gcgactttgt ttgtcacatc ataccgatta gaaagctcaa aataatctct catagcccgc
     8401 atagtgatgt tgttatcact gctttctgcc agatacgtcc ccataatttc tgggatggct
     8461 ttctcgtaca gcggatgtag tgcttctacc cgctggatac tcattttccc ttcagtaatg
     8521 gtccctgttt tatccaagca taatgtatcg acatgggcca gcgtttcaat tgaatacatg
     8581 tcttgaacaa ggattcgttt ttttgccagt ttggttaccc ctgtcgttaa tgcaatactt
     8641 attagcaata ccaaaccctt tggaagcatg cctaacaaag ctgctgcaga tgcaataaca
     8701 gaaattttga tagaagcatc gcggatgaac agtgcttcca aaaatagtat gatccccaaa
     8761 ggaataatca cgaaactagt gaatttggat actttgcgaa tcgaatctac aagttcagaa
     8821 cgaatagctt tgtgagtctt tgcctcgcta gtcaagcgga cagcataatt atctgcacct
     8881 actcggataa cttcagccat gacagaaccg cttgtcaaaa agcttccaga aagcaattca
     8941 gctccagttt ctttgacaat caaatcagat tcgcctgtca aaagagcttc atttgcttct
     9001 gcccgtccag atataacctg taaatcggct ggtatctgtt ctcctgctcc gatttttacc
     9061 aaatctccta ataccagctc tttagtagaa atcgattgtt ctttaccgtc ccggatcact
     9121 agtacttctg attgggaaac aatcgataat ttccgtacaa gatttcttgc atgtatttct
     9181 tgataaattc caataacgat attgacgaca ataattgcta aatacgccat gttggaatac
     9241 gcacctacaa ataacagaca aatcccaata ccaaagttca gaaaattgaa taacgtcaat
     9301 atattatcgc tgaatatttg ttttgtactt tttgatgcat cttcctggta gtcattttgc
     9361 tggccagaag ccattttctg aactacctct tgctgtgtaa gtccattcat tttctttttc
     9421 tccattttcc gccaactttc aaaaataatc acgtgtttaa gtctagcgtg ttccaagatt
     9481 aaaaacaact tgtttttata aaatttatag aaaaacacac gaatgatttt acaaaaaaga
     9541 tgccaacctt tttgtttgaa tcacccgtgt gctgttttta ttatcaatct atctttactt
     9601 atattgttcc tccaaacggc tcatccacca acctagtgct gtaccggcta taaaaagaac
     9661 aggacaagct agtaccccag caactcccaa tcccgcgtaa tcggtaggaa tgatcataat
     9721 cgttgaagca aaaactacac ctaaaatgaa atggaatagc ttgctatatg cctttgagaa
     9781 aatgtaatcc atgatttttg acaatccaag aacacaaaga atcccaccaa ttccgatcgg
     9841 cacaatcact tcaagtcgta cttctttaaa tccgtcagcc atcgctttat acaatcccat
     9901 atacaccaaa aaattagaag ggctcaatcc tgggacgatc atacccaaac caatcaatcc
     9961 gccggcaatc agccatgttc caaaattctg atcgacttgc ccgtcaaata attgagcgcc
    10021 gtataataaa aacaaataag ccagaacaaa agtaacaacc atgatgatca catcagaagt
    10081 atctcttcct tttttccctg cttctttcca taacgcagga acagttccag cgatacatcc
    10141 gacaaaaaac cataatatcg ttgtttcata cgcacctaat aaaaaactga ctaaaaaaga
    10201 aagtagaaag atgcctgtca ctccgcctag accaacaggc agaaaaaaca aaacattttc
    10261 tttgaaattt tttgtaaggt gggctaaaaa agaaatcagc cgctcataca tgccaaagac
    10321 agctgctaat gcaccaccgc tgactcctgg caagataaat cctgaaccga taaacattcc
    10381 cttcacaaac cgtaacatcc agtctttggt tgtgtacccc acttcttgat tttccatttt
    10441 ttgccttttt tccactattt gcgcactcct tctttcattt aattttattc atgattgaac
    10501 atttcctgct attttactta aagacttttt cataggtctc tattattttt tcattcattt
    10561 tgacaatatc aggataaaac atgttacctc cattatgata gagatagccg ccattgtaaa
    10621 gcaaggactg gatccgccaa tatcggtatt gtttcccttc ctcatttcct aaaagtgggc
    10681 tcagcacatc tttagaatac gcttctgcta attctactgt gttttctccg ccatgatttt
    10741 ttacataggc aatataatct ttcccaaaat tatatgcttg gacagctgtc cataaatcgc
    10801 atccttgttt ctttgcttct actatcattt ccgccaaata tttgacacct tgatcaatac
    10861 tgtcagctgg attatcaatg atctcagctt ctccatgcag actttccgag ctctgcatga
    10921 gatctgtccc ttttcctttt gattcggtca atattatcgc cttgatcaaa ttctcgtagt
    10981 tttccatatg ataatttttt gcagctgttg ttatttctat ttgatagctt tccactcgtt
    11041 ttaccgaacg ataagttctt cctcataaaa acaacaccgc accaataacc gtcagaatga
    11101 tcatgtaaaa aagaatacgg ataatagata atcgttttcg cttcatttca tcacctagtt
    11161 attttgacat ctttttttat cttactattt ctttatcttc ttggctattt cttccttgat
    11221 ttctgtgtac gccttaagaa aaaatgaatt ttcctgtatt ttttgacatc ttacgaaaat
    11281 gatcgttgtt tttcagtaaa aacaattgcc caatgactga tataatcgtt atactttaca
    11341 cagtaggtga ttatgtgaaa aaagaaaaga aatatgcaaa aatgccagat gggagcgaaa
    11401 tttactatga aaagagcggt caaggcttcc ctctcttttt actgcatggc aatgacggca
    11461 gcggccgctt tttttcagaa caggtccctg tactcgaacg ctactatacc gtgtatctag
    11521 tagatagccg aggacatggt cgttcgacaa acgaagcatc tatgttgaat tttcagttaa
    11581 tggccgagga tctgaatacg atcatgttgc tggaaaaaat cgatcaggca gattttcttg
    11641 gatttagtga tggagcaaat ctagcactgg tatttgccag cagcttccct aaaaaagttc
    11701 atcgattgat tttaaattct ggaaacacgc ttgttaaagg cgttcgtttt tctgccagag
    11761 tcatcagtaa tattcattat gcatgggtat ggttactctc tttatttcgc ccaagtcttc
    11821 gcaaaaatct tttagttatc aaacttttgc tgcatgacat cgggcttaca gaaaatgatt
    11881 taaaaaaaat caactccccc actttgatca tcgtgggaaa aaaagatgta atcaagctaa
    11941 aacattcttt gtatatagct aaaactatac caaaagcttc ctttgtgctt gtgaaagaac
    12001 aaggacatga attagctaga aaagatcctg aacgcttcaa tcgagaagtt cttcaatttc
    12061 tttctgaaac ataactatta ggaatagaag gtgatttatt tgttaaaaaa taccatacaa
    12121 tggctgaaaa accacctagg actgttcaaa acaatctttt tgatttctgt cattgtcatt
    12181 attgtcggtg aattgatgtc catcggtaaa actctatcta tccagcaatt aggagaaacg
    12241 tttgccacta tacctgtatg gaaaagcgga ctaatgctat tgattggtct tatctctgtg
    12301 ttacctatgg ttggttatga tattattttg aatcggatgc ttgaacaaaa gcagaatcct
    12361 cgttacctgt ttgagacaag ctggctgatc aatacgatca acaatattgc cggtttcggc
    12421 gggtttgtta gtgtggggct tcgctctgaa ctatatggac aaaagaaaga gagcagaaac
    12481 gtgatccaag cattatcgaa agttttcttg tttttgatgg ctggactttc tatttacagt
    12541 ctgctttctt ttttacttgt agtcttcacg ccagttgctc cttttttgaa gcaatattgg
    12601 atatggttga tcggcggcgg tctatatttt cctgtcgtct ttttatttac tactttcaaa
    12661 aagaaaggat tccttggtgg tacctcactt aaaactcaag gacagctatt gctagtttca
    12721 ttgttggaat ggaccggtgt cctgtttagt ttcctttctg ttggttattt aatggaaatc
    12781 cggattgatc tgtggcaaac aattccatta ttcattgctg cttcagtgat aggaatcgtg
    12841 tctatgattc caggagaaat tgggagtttc gatgtaatga tgattatcgg gttgtccgct
    12901 attggtgtgc caagagaaat agtcgttgtg tggatcttgc tctatcgcct gttctactac
    12961 atcattccgt ttttgattgg aatcgtcttt ttcttcaaaa atatcggttc cacttttgat
    13021 cagcgttatt ctggtatccc taaacaatta gcaacagaaa ttgcgcataa aatcgtggtt
    13081 gtcttattat acttttctgg aatcatgcta gtactttctg ccactatccc gcaagctttt
    13141 acagagtttc gctggcttca tagtttgaac ccattgaaat ttcattttat tatccaattt
    13201 cctagtatac tattgggatt tcttttaatc attatgggca gagggatcgc agcacgtgtg
    13261 aaacgagcat atttgcctac aatcttcttg attgttctag ctttacttta tgttttatta
    13321 agtgatttta gtttcacacc ggtggttttc ttgtctattc tgcttctgat cattcttgct
    13381 tctaaaaacg aattatttcg ggaacaattg atctattcat gggagtggcg tacgatcgat
    13441 ggaatcatta ttggtgcact gtccttgctt tacatcgtta ttggggtata caatctgccg
    13501 gatttccctc atcggcgtca ccattttatt tcctttttct tatttccttc tgaaaagatt
    13561 tggttttcgg gattgttggc catcatcgct gttagtttca tgatcgttct atttgttcat
    13621 ttccttcaag gagaaaagaa acagattggc gaagccttta atgaagaaaa ggccctgaag
    13681 atccttacaa cttatggagg aaactccgat agtcaattga tcttcttaaa agataagcgg
    13741 atgtttgcct atgaaaaaga cggtgaacca actgttcttc tccaattcgc ttgcttcaat
    13801 aataaatgta ttgtaatggg tgatccttct ggtaagaaag aagattttcc agaagcaatc
    13861 gaagctttta tcgaagaaac agatcgacta tgctatttac cagttttcta cgaaacaagc
    13921 gaagagattg ttatgatttt gcatgaattc ggctacgatt tcattaagat gggggaagaa
    13981 gcttatgtag acctgaatag ttttacaact tcagggaaaa aaatgaaggg cactcgtgct
    14041 gtcttgaatc ggatcgaacg agaaggattt acatttgatg tcttacaacc accattttct
    14101 actgagcaaa tgagtacttt caaaaatatc tctgataatt ggttgggttc acgaaaggaa
    14161 aaagggtttt ctttaggctt tttctctgaa gattatctac aaagagcgcc tattgcagtt
    14221 gtcaaaaata cccaagaaga aattgtcgct tttgcaacga tcatgcctac ttacacgaac
    14281 aataaagtag gaacgattga tctgatgcga tatgattcta aaaaagcacc ttctggcagt
    14341 atggatttct tgttcttgca tttgtttgcc tatatgaaag aagaacatat ccaatggttc
    14401 aatttaggga tggcccctct ttcaaatgtc ggaacttcca gaaagagttt tttacaggaa
    14461 aggattgcat acttggttta cgagtttggt tctcattttt attctttcca tggattaaga
    14521 gaatataaaa gcaagtacgc tacaaactgg gtctcacgtt atactctata ttctagagat
    14581 agttggattg catatgttat gattgctttg ctgattattg ataatgcgcc agttgagcag
    14641 acacaaggta gaataagtgg tttgaaaaaa tggatacgaa gaaagtatta aaaactgcat
    14701 accgatagat gaacactctc atgatgaata aaagagactg aagtaaaacg aaagttcatg
    14761 cttctacaat ctcttcttat acaattgaag aacaaagagc ggtccaaaca gaaatcctgt
    14821 ttggaccgct cttttatttt aaacattttt cattaccaaa atattcgagt cgcgtttctt
    14881 atgcttcgat ctctgtaacg atacctgaac ctactgtccg tccgccttca cgaattgaga
    14941 atgtcgttcc gttttcaaca gcgattggat ggatcaagtc aacatcaatc gtcacgttgt
    15001 caccaggcat gaccatttct gtatcttctg gcaatgtgat tgttcctgta acatcagttg
    15061 tgcggaagta gaactgtgga cgatagttgt tgaagaatgg agtatgacgt ccaccttctt
    15121 cttttgtcaa cacgtacact tctgctttga attttgtatg tggagtaatg gaacctggtt
    15181 tagcaagtac ttgtccacgt tcgatatcgt cacgttggat cccccgtaac aacacgccta
    15241 cgttatcccc agcttccccg taatctaacg ttttacggaa catttctaca cctgttacaa
    15301 ctgctttttg tgtttcaggt ttgatcccta cgatctctac ctcatcaccg acacgaacag
    15361 caccacgatc aatacgacct gaggcaacag ttcctcgacc tgtaattgag aagacgtctt
    15421 ccactggcaa tagtaatggt ttatctgtat cacgttctgg tgttgggata tattcatcta
    15481 ctgtatccat caattccata atagcagctt cagcatctgg atcgccttgc aatgctttta
    15541 atgcggaacc tttgatcaca ggagtgtcat cgcctgggaa accatattcg ctcaataact
    15601 cgcgaacttc catttctacc aaatcgatca attcttcatc atcgactaaa tcaactttgt
    15661 tcaagaaaac aatcaggtat tttacaccaa cttggcgtga caataaaatg tgttcacgtg
    15721 tttgaggcat cggaccgtca gttgcagaaa caactaagat tgcaccatcc atttgtgctg
    15781 cccctgtaat catgtttttc acatagtccg cgtgtcctgg tgcatcaata tgcgcgtagt
    15841 ggcgtttttc tgtttcatat tctacgtgtg cggtattgat cgtaatccca cgttcacgtt
    15901 cttctggagc tgcatcaata ctagcatagt cttgaggatt tgctaggcct tttttgccta
    15961 atactgtagt gatcgcagca gttaaagtag ttttcccatg gtcaacgtgt ccaatcgtac
    16021 caatgttaac gtgtggttta cttctgtcat aatgttcttt tgccataatt tacaaacctc
    16081 ctaaataata tagatcactg aaaaatttca gctctcacct ttttattata gtcttttttt
    16141 gactaaatca aaaagaatac gtccgactta ctttttgtaa gattcgaact aagcttatta
    16201 tacgtcaata ttggtcaaag tcaactaaga gcactcgtct gtcttatacg cgaaaaaagt
    16261 accttttata aataaaaaaa tgtgtttttt gagaaaaact tcaagatagt ccttaacttt
    16321 cttttgaagc aataagaaca aaatgaggaa aagtttaaaa ttcagctgtt gccaacaact
    16381 ttcaatagac gaaatcttct atttcgttaa taataaggaa agaggtgaag tacatgaaaa
    16441 aattaattgg cgtacttgtc gttttaggca tatttctcgg cggaagtttt gcagcttatc
    16501 attattttta cggcggcgaa gcttattata caaaaatcac gacgaatggc gaaatgtcag
    16561 ctacccaagc agataacgga gagaaattca cgacttatac ctacaagcaa gcggcttata
    16621 ataaagatgg tgaaaaaaaa caggtgacgc ttcgcgaaga aagagaacat ccattaaaga
    16681 tgaatgcgta tcttaaactc aaagtcaatc ctcgtaaagg tgtattaagc tgggaagaaa
    16741 taaaggcttc tgaagtgcct aaaaatgcgg cagaaaaaat cgataattag taaatggtct
    16801 taaaatttta ttagataaaa agaggctggg acagaagcgt ttaactccaa gaaataagaa
    16861 ggagttgctt ctgcttccgc cgtttatacg tgtttagagc gtgagacaaa agtgttcttt
    16921 acttttgtct cacgctcttt ttttgttata ttcgtctttt ccgatccttc tcttgacaca
    16981 attcatttaa ctgatcactg gtacttgaac acctaatatt ctagtcattt ttataaacga
    17041 ttcaatactt catccacatt tttgatcatc acggatatcg taccatccgg attattcaca
    17101 aattcaatca aatctgggtt gcgatataca tctactggta cgatcagttc gatcccgttt
    17161 gatagcttga atttttgttt tccaaatttt ttctcagaaa tttcttgtac ttcttttaca
    17221 ggaggtgctt ctgggacaaa tccttgctct tgtacttctt ctttaaaagc catttttgcc
    17281 gtgatgtttt ccttgaagac tttttccgca atcatctcat gatccaaccg acctttttct
    17341 tctatcgtat catagacagc ttctttcaaa tcagccatga tatcaaattc ttctgtctca
    17401 aatttttttc caagatgctt ggctactttt tggatcactt ttacattttc ttctaaagaa
    17461 ggtgcaggaa cactttcgat cactcttcca gaaaaataaa gctctttttt gccagaaaac
    17521 tcatattttt tttcaattaa ttcgtaggtc caatcagtca aattcacagc gaatgcttca
    17581 tctgcttttt gtgttttcgc ccctagaatt gctcgattca aaatcaagcg gttgtcgatc
    17641 cctgcttcgt ctgcttcaac aaagtgagtg taagcctcac gataattgac tttcaataaa
    17701 gataagtaca tcactgtatc taattcatac aagacaacaa atacatctgc actaggtgct
    17761 tcttcacttt cttggtagat atcgaaccac cgctgaacga ttgcttcact tgcttccaca
    17821 aaattttctt gagcgatttt aagtgattca acgatcatgc tttcttctgc tagttgtcca
    17881 gtttttgttt gagcagaaga gattttttgg atcttctttt gaagaaaatc acgaatatat
    17941 tcttttgtca gatccagctc tttttgtgaa aagactggag aaccagtttc tctgtcaata
    18001 atatgcagaa ttgctttttt taaatagata tccattttct cattcccttc tgtcttagtt
    18061 tacggaaaaa aaatcaaaaa taccagaatc aaaatcattt tcttttaaac aaaaatttca
    18121 agagtagaaa caaaatggat tctttttttc gaaaaatgcg ctacacttat agttgaacga
    18181 ataaaaaagg agctgaaagt atgaattcat taacaagcac ttatcgtcta tcaaatggtt
    18241 acgaaatccc ggtagtagga ttcggcacat ggcaaacacc tgatggggat gtcgctgttt
    18301 cctctgttaa agaagcgctg gctgcaggtt atcgccatat cgatactgcc caaggataca
    18361 agaatgaaga aagcgtcggc caagcgatta aggaaagtgg aattcctaga gaagagatat
    18421 tcttgacaac aaaattatgg aatgcaaacc acagctatga acttgtgatg tcttcttttg
    18481 aagaatcatt gaagaagctc caaacagatt atttagatct gtttttgatc cactggccaa
    18541 accctgttgc ttttcgtgat aattgggaac aagcaaatgc agatacatgg cgagcatttg
    18601 aagaactgta tgaagcaggt aaaatcaaag caatcggtgt gagcaatttc ttaccccacc
    18661 atctagatac actagcaaaa acagcaaaaa ttatgccgat ggtcaatcaa gttttccttg
    18721 caccaggcga attacagaca actgtagttg agtatgcaaa aaaacatgat atgatcctcg
    18781 aagcatatag tccattaggc actggtaaaa tcttcgatgt gcctgaaatg aaacaaatcg
    18841 ctgaagcaca tgacaagacg attgcacaag ttgctttgcg ttggtcgctg caacacgaat
    18901 tccttcctct tcctaagtca gtgacaccaa gcagaatcaa agaaaatact gaattatttg
    18961 attttgaatt aacagaagaa gaaatgaaac aaatcgatca gttagatggt gtagtcggca
    19021 aagcaaaaga cccagatact acccaatttt aagtcgaaag gtgattttat ggatccaatc
    19081 gaacgcttga attctctctc ggaagaagtt acccagactt ttcattccga ttttgtcttt
    19141 ttgatcgatg cagagaaaat ccaacatttt cctgcaagaa actggacaca tgatcaaatc
    19201 atcgaagaac tgaaaaaacg gttcgatcat tcgctaatgg tcaaaccctg gcacgaacat
    19261 gaagtcattt attcacctga actacctgtt tttgccttga taccgaaaaa atagaaagaa
    19321 tggaacggat tatgtatata ta
//
LOCUS       DACDLM010000055        19312 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.055, whole genome shotgun sequence.
ACCESSION   DACDLM010000055 DACDLM010000000
VERSION     DACDLM010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.055"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            218..772
                     /locus_tag="IV356_002001"
     CDS             218..772
                     /locus_tag="IV356_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP9015670.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
     gene            complement(945..1418)
                     /locus_tag="IV356_002002"
     CDS             complement(945..1418)
                     /locus_tag="IV356_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP9015671.1"
                     /translation="MRIKPIKDGEQLLFSSEENKPLYLDYVNHNLKIIIKENNLKHIT
                     LHGFRHTHCSLLFESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFM
                     SSTEEKQGSLQKVKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            1430..1966
                     /locus_tag="IV356_002003"
     CDS             1430..1966
                     /locus_tag="IV356_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAP9015672.1"
                     /translation="MPARIHHISIVNRFIRPTFDFYHNILGLKLLMKTINQDDHTMYH
                     LFFSDNHHRVGTELTFFEVQEGNNQFFGTNTIERTILKVPSEASLHFWEIYFETQGVC
                     HYGIESFSGRPILRFEGPDATRLALVPLREFEDIDDYFPYVTDQIPTEHAILGIDAIQ
                     LRVQYSDATERELLSVGW"
     gene            2006..2377
                     /locus_tag="IV356_002004"
     CDS             2006..2377
                     /locus_tag="IV356_002004"
                     /inference="COORDINATES: protein motif:HMM:NF013098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAP9015673.1"
                     /translation="MTILENQDTQFYQEVQIIQDRENPVAIEGIGSVHHVAFGVENKS
                     DLQRIDKQLQERNFINSGIKDREFFVSLYYRDPNQLLIEIATGEGNLDAKAYENQSPR
                     FEEIPLFLPQYLNFIREQVEQ"
     gene            2661..3932
                     /locus_tag="IV356_002005"
     CDS             2661..3932
                     /locus_tag="IV356_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HAP9015674.1"
                     /translation="MKLSTQEKQLKNVSLKIPKNKISIFTSVSGSGKSSIVFDTITQE
                     AGRQLNDTYDSFTRLFLPKYSRPEVDEIDNLSTAIVVNQKKIGGSARSTLGTITNINA
                     LFRVLFSCFATPSLGYANAYSFNDPSGMCSVCQGIGKTIAFLIGLLYFSAIDNADFVF
                     SDPFTAEVLSGIEEQAKNHGYFVLVHNVNSAEDVKTIQRNWRFEGFIVVGVRVKEFLE
                     LNNVFDGPVVYIDTHLSKETLRELEQQMNRLFVNTNDYQASTLAVEHLIHYGHEKIAF
                     LSFDYIVGEPSVIQERHQAYIDTLKKYHLTFKSHWIYNNSEFERIYQELAEFTAIVVT
                     GDYLAAKLVKFLKNKNKRVMEQLSIIGFDDITFAELMDPALTTIRLNPGNKGAIAFHQ
                     LIGLAKQEEIKNQVLLLEGELISRDSVHKIK"
     gene            4177..5202
                     /locus_tag="IV356_002006"
     CDS             4177..5202
                     /locus_tag="IV356_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP9015675.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            5496..6605
                     /locus_tag="IV356_002007"
     CDS             5496..6605
                     /locus_tag="IV356_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAP9015676.1"
                     /translation="MLDEFEKQNPDIKVEMETTPWDQYWVKLEAATTGGNMPDVVTMH
                     SSESYKYMSQNALMGLDDVIKENDIDMGNFTEGIADFYTLEDELYAIPKDASVVGLWY
                     NKELFDNAGVDYPDETWTWETLRQAAIDLTDESKGIYGFASHIGTETGYWPFIYQNGG
                     EVFADDNTKSGLNTPEAQEALAFYRDIALVDHASPTITELQDPDKLSRFQSGRLAMMI
                     EGNWFAPGFLKNDYLVENVASAVLPKGKVNATITNGLGWAASASTKYPEEVKKLMAFL
                     ASEDANKIQAETGASIPALKGFEDEWAASSDTIDLSAFGKMLEYGVPRPYNKDGLRAE
                     QAEVQIINRILSGEVTVEDGTAQIEKEVNAILSGN"
     gene            6688..7584
                     /locus_tag="IV356_002008"
                     /pseudo
     CDS             6688..7584
                     /locus_tag="IV356_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008378728.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            7600..8424
                     /locus_tag="IV356_002009"
     CDS             7600..8424
                     /locus_tag="IV356_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002579255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP9015677.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            8456..9766
                     /locus_tag="IV356_002010"
     CDS             8456..9766
                     /locus_tag="IV356_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HAP9015678.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            9914..11173
                     /locus_tag="IV356_002011"
     CDS             9914..11173
                     /locus_tag="IV356_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP9015679.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            11183..12055
                     /locus_tag="IV356_002012"
     CDS             11183..12055
                     /locus_tag="IV356_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP9015680.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            12067..12897
                     /locus_tag="IV356_002013"
     CDS             12067..12897
                     /locus_tag="IV356_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP9015681.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            12937..15120
                     /locus_tag="IV356_002014"
     CDS             12937..15120
                     /locus_tag="IV356_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAP9015682.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDKTVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            15181..16401
                     /locus_tag="IV356_002015"
     CDS             15181..16401
                     /locus_tag="IV356_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligo-1,6-glucosidase"
                     /protein_id="HAP9015683.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            16398..17858
                     /gene="gtfA"
                     /locus_tag="IV356_002016"
     CDS             16398..17858
                     /gene="gtfA"
                     /locus_tag="IV356_002016"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HAP9015684.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            17935..19041
                     /locus_tag="IV356_002017"
                     /pseudo
     CDS             17935..19041
                     /locus_tag="IV356_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
BASE COUNT         6576 a         2932 c         3749 g         6055 t
ORIGIN      
        1 ctaaaattta aataagagct tagaatcttc atataagtaa ggttaatttt tttgtacaaa
       61 aaagtcggaa tattctgagt tactgaaatg atataaaatc ataaactaaa tcccttgatt
      121 ttattgactt tcaaaagttt atatatataa gttaatgatt atggtaaaat atatacataa
      181 tcattaactc agaatatttt taagaaggga aacaatagtg agctataatg tacaaccgtt
      241 aaggacaaat gaagagatac aagattttca gttttggcta agaagaacaa gtaatccgga
      301 aagagatagt tttttatttt tgtttggaat caataatggg ttacgtatgt cagatattat
      361 aggattaaaa gttggagata tacgaggcaa aagtaagcct attattgttg aacataaaac
      421 aggtaagcga aaaccgattt ttatagataa tttgagagaa gaaattttat tatatactga
      481 aggtaaagaa gaaaatgatt ggttatttcc gagtcggcaa caaggtcgac atataacaag
      541 ggatcgtgtc tatcagatat atgcagatat agcagaaaaa ttaggacgag atgatatagg
      601 aacacataca ttaagaaaaa cttttgggta tcactactac aagaaaacta gagacattgc
      661 taccttaatg tttattttta atcatagctc gcaagcaatt acaaaaaggt acattggtat
      721 aactgaagat gaaataggag catcacttcg tggatttaaa ctaggtgtat aatttaaaaa
      781 tttttataaa cagtaaagac aaagattaaa agctattttt atctagaacg attttatttc
      841 ataaagttcg cggaataaaa gctggggtta ctggtacttg gtataggttc gtgttatata
      901 aactaagtaa ttaaataaca tttttaggtt ggaaaaggat gaaattaaaa aaagagaatc
      961 aatacggtct caaaaacgca aacgctgcgg aataagaaaa atactgataa ctcaacgttt
     1021 agcagactat ctaataggga tagtctgctt ttttcgtttt tgaccatact tttgaccttc
     1081 tgcaaacttc cttgcttttc ctctgtagaa ctcatgaaat ctgcaaaacg aattgccgtt
     1141 tcctctgtct gctttttcgc gatatgggtg tatatatcat ccatagtggt tttaatatct
     1201 gtatgtccaa gtcgaacata cacttctttg acagacgcac cagattcaaa gagcagacta
     1261 caatgggtat gacgaaaacc atgaagtgtg atatgtttta agttattctc tttaatgatg
     1321 attttcaaat tgtgatttac atagtctaaa taaaggggct tattttcttc tgatgaaaac
     1381 aaaagttgtt caccatcttt tataggtttg attctcattt ttagatatta tgcccgcacg
     1441 tattcatcac atttctattg tgaatcgctt tattcgaccg acatttgact tttatcataa
     1501 tatactcggt ttaaaattac taatgaaaac aattaatcaa gacgatcata ccatgtatca
     1561 cctgtttttt tcagataatc accaccgtgt gggaactgaa ctgacttttt ttgaagtaca
     1621 agaagggaac aaccagtttt ttggaaccaa tacgattgaa cgaacgatac taaaagttcc
     1681 ttccgaagca tcattgcatt tttgggaaat atattttgaa acacaaggcg tttgccatta
     1741 tggaatcgaa tcattttctg gacgacctat cttacgtttt gaagggccag atgcaacacg
     1801 attagcttta gttcccttac gcgaatttga agatattgat gattatttcc cgtatgtcac
     1861 agaccagatc cctacagagc atgccatttt aggaattgat gccattcaac tacgcgtaca
     1921 atattccgat gcgactgaac gagagttatt gtcggtaggc tggtagcaca aagaatacgt
     1981 cagtttcttt tcgggtcatc aacgagtgac aatcttagaa aatcaagaca ctcagttcta
     2041 tcaagaagtt cagattattc aagatcgtga gaatccagtt gccattgaag ggattggtag
     2101 cgtccatcat gttgcgtttg gcgtagaaaa taaatctgat ttacaacgca tcgacaaaca
     2161 attacaagag cgcaatttta taaattcagg aataaaagat cgtgaatttt ttgtatcact
     2221 ttattatcgt gacccaaatc aattattgat tgaaattgct acaggggaag gaaacctaga
     2281 tgcaaaagcg tatgaaaatc aaagtccacg ctttgaagaa attcctttat ttttaccgca
     2341 gtacttaaat ttcattcgtg aacaagtgga gcaataatta gctaatcaaa tccatgacga
     2401 agagtaagag gttgactcat aagtcaaaaa ataaagaaaa acgcatcaaa tccattctaa
     2461 agaatgttga tttgatgcgg ttcctatttt tataaactat cattttcgac taataaaact
     2521 acttatgagt cagcctctct ttttttcttg atttttatac ctctttctag gtaaactaaa
     2581 catctgccaa aaataccgtg tctcattgaa acattctcaa ctatttcaaa ataaagggga
     2641 gtaccaaatg aacgagtata ttgaaattat ccacgcaaga gaaacaactt aaaaatgtca
     2701 gtctcaaaat tcccaaaaat aaaattagta tttttaccag cgtatctggt tcaggaaaat
     2761 catcgattgt ttttgatact attacccaag aagctggtcg tcaactgaat gacacctatg
     2821 atagttttac ccgtttattt ttacctaaat acagtcgtcc agaggttgat gagattgata
     2881 atctttctac ggcgattgtg gtcaatcaaa agaagattgg tggcagtgcg cgctcaacgt
     2941 tagggacgat tactaacatc aatgcgttat ttcgtgtgtt gttttcatgt tttgcaacac
     3001 ctagtttagg atatgcaaat gcttattcat ttaatgatcc tagtggaatg tgttctgtct
     3061 gtcagggaat cggtaagacg attgcatttt taataggatt gctttatttt tcggctattg
     3121 ataatgctga ttttgtattt tctgatccat ttaccgcaga agttttgtct ggaattgagg
     3181 aacaggcaaa gaatcatggt tattttgtat tggtgcataa tgttaattca gcagaagatg
     3241 ttaaaactat tcagagaaat tggcgttttg aggggttcat tgttgttggt gtacgtgtaa
     3301 aagaattttt ggaattaaat aacgtttttg atggtcctgt tgtttatatt gatacgcatc
     3361 tttcaaaaga gacattaaga gaacttgaac aacaaatgaa tcgtttattt gtaaatacaa
     3421 atgattacca agctagtaca ttggcagtgg aacatttgat tcattatggt catgagaaaa
     3481 tagcgtttct ttcttttgac tacattgtag gtgaaccaag tgttattcaa gaacgacatc
     3541 aagcttatat cgatacatta aagaaatatc atttaacctt taaatcgcat tggatatata
     3601 acaactctga atttgagcga atttatcaag aattagctga atttactgca attgttgtta
     3661 ctggagatta tttagcggct aaattagtaa aatttttaaa aaataagaat aaacgagtga
     3721 tggaacaatt atcgattatt ggatttgatg atattacttt tgcagaatta atggatcctg
     3781 cgttgacaac aatacgacta aatccaggta acaagggggc gattgctttt caccaactga
     3841 ttggactggc caaacaagaa gaaataaaaa atcaagtact actattagag ggagaattga
     3901 tttctcgaga ctctgttcac aaaatcaaat aaaaaagctc tgtgaaataa gtatagttaa
     3961 caataaaata tccgaacgat agagagaatg aactgtgatc tagcagttcc tcgtcgcaaa
     4021 ttcactagaa ttagcattat ttactctaaa ttgttcggat attttttctt gtttttaatt
     4081 atgattacag tgcctatttt taacgaaatt tgcttatttt caaaatgtat gattatatgt
     4141 tagtaaacac tttcaaatat gaaaagagga gctattatgg taggaattag ggatgttgca
     4201 aaacgggcgg gtgtgtccat tgcaacagta tcgcgcgtgc taaatgagga tccgacactt
     4261 tcagtaaccg atgaaaccaa acgaaagatt gcagaatcgg ttaattttta tcattatgtc
     4321 aaaaaaagtc ccgttgcaaa aaatttaaca aatattgcat taataacgac agtttctgaa
     4381 gtagatgagt tggaagatcc ctattttcga acgattcgca gagggattca agtcgaagca
     4441 gaacaaagca aagtcaattt gaagaaaatt attcgtttgt cagaaacacc gttggagcaa
     4501 gacgatttgc taaaatgtca aggtgtgttg attattgggc aggtgctatc ttctgtgatt
     4561 gaagaagtat cagcaattaa ttcgaatgtc gtagtgattg atgaccctag tattgaagct
     4621 gaagtagatg cagtttatac tgatttaaca aaagcaacga atcagcattt agatcgattg
     4681 tataaaaaag gacaccgaaa cattgcgttt atcggaggag gacgtgttcg tttagatagc
     4741 caaggaaata aacacgtgtc agatgatgat tatcgaaaaa tagcctatga gacgtggatg
     4801 aaacaaaaag gattagaaaa atatagtcaa atttatttag aaggctggac cacacttgac
     4861 ggaatgcagg cagcagattt acttttgaaa aaacatgcta aagataagtt gccgactgct
     4921 atcatggtag gaaatgatcc tattgctgtg ggggtttatc gttcacttca aaaaaatggt
     4981 ctacatattc cagaagatat ttcgattgtg agttttgata atattgaagt tgctgaattt
     5041 ttaacacctg cattaaatac ggtgaatgtg aatacagaag aaattggaaa actagcagtt
     5101 cgcatggtta atgaacgaat aaaagaagtt agaaatgttt cgatcaaagt gattgtttct
     5161 aataatatta ttgttagaga aagtgaaaaa aatatcgatt aaaaaagtaa acatccaaaa
     5221 aagggtgttt acttttttgt ttactaatat ttttagtaaa aaatctcgac aaaacattaa
     5281 gtaaacagtt atggtgttgt taacaaaaag aaaacgcatt caaaacagga ggaattaaga
     5341 tgaaacattt caaaaaaata gctttaacag ggatagctgt tttaactggg acattactcg
     5401 cagcatgtgg tgggggagat agtaattcta aagacgggca agtaacttta agctatgcga
     5461 gttgagatac tgaccaagct ccaggactaa gaaaaatgtt agatgaattt gaaaaacaaa
     5521 atcctgatat caaagtagaa atggagacaa cgccttggga tcaatattgg gttaaattag
     5581 aagctgcaac aacgggaggt aatatgccag atgtagtaac catgcactct agcgaatcct
     5641 ataaatatat gtcacagaat gctttgatgg gacttgatga tgttatcaaa gaaaatgata
     5701 ttgacatggg aaactttact gaaggaattg ctgatttcta tacgcttgaa gacgaactat
     5761 acgcaatccc taaagatgct tctgtagtgg ggctatggta caacaaagaa ttatttgata
     5821 atgcaggtgt cgattatcca gatgaaacat ggacatggga aacactcaga caagctgcaa
     5881 ttgatttaac agatgaatca aaaggcatct atggttttgc atcacatatt ggaacagaga
     5941 ctggctactg gccatttatt tatcaaaatg ggggagaagt atttgccgat gacaatacaa
     6001 aatcaggttt gaatacccca gaagcacaag aagctttagc tttttatcga gatattgcac
     6061 ttgttgatca tgcttcacca acaattacag aattacaaga tcctgataag ttaagtcgtt
     6121 ttcaatcagg tagattagca atgatgattg aaggaaactg gtttgcaccg ggatttttga
     6181 aaaatgacta tctagttgaa aatgttgctt ctgccgtgtt acctaaggga aaagttaatg
     6241 caacaattac aaatggactt ggttgggctg ccagtgcgag tacaaaatac ccagaagaag
     6301 tgaaaaaact aatggcattt ttagctagtg aggacgccaa taaaatccaa gcggaaacgg
     6361 gggcatcaat cccagcacta aaaggctttg aagacgagtg ggctgcttct tcagatacaa
     6421 ttgatttgag tgcttttgga aaaatgttgg agtatggagt ccctcgtcca tacaataaag
     6481 atggattacg agctgaacaa gcagaagttc aaattattaa ccgtattctg tctggtgaag
     6541 taactgttga agatggaacc gctcaaattg aaaaagaagt caatgcgata ttgagcggaa
     6601 attaaattag ttaattatac aatatacagg cgaaaggatt ctatttcgtc tgtatattaa
     6661 tggatgaata ccaaaaaggg ggatattatg aaaaatcgaa tttttggaaa atatcgtaaa
     6721 gatcaagtga tatggggcta tatttttatt tttccaacgg cattaggatt aattttatta
     6781 aatatatggc cagcaattca aacagcaatt ttaagttttc aaaaaacggt agggttcggt
     6841 gatactgaat gggtcggatt aagaaattac caaaaaatgt ttgcagacgg tgaagttttt
     6901 cagtctttat taaacacatt aatttatgca gtggtttcga tacctagtat tgttgtatta
     6961 tccttgttgg tggcagtttt aatgaataga aaagttaaag gattgtcgat ttatcggaca
     7021 atttattttc taccagtcgt tgctgcacca tccgcagtcg caatgatttg gcgctggatg
     7081 ttcaataatg attatggact gattaataac atgttggcta aaataggtct cgatggacca
     7141 gcatggttaa cggatccatc gattgcgatt tattctatta tcattgtagg agtttggagt
     7201 gctattggtt ataacatggt gttattacta gccggcttat aagaaattcc taaagattat
     7261 tatgaagcag cggaaattga tggtgctagt ccaatccagc agtttttcaa cattacgtta
     7321 ccattagtta caccaacatt attttttgta gttgtaacaa cagttatcaa tgctttccaa
     7381 gtatttgatg ttatttttat gatgattact cctaatagta ccgccatgtt taaatcacaa
     7441 tcattagcct atttattcta taaacattca tttattttaa atgacaaggg atatggttcg
     7501 gcaatcgtta tgttcctttt agtgattata ttaattatta ctgcaattca aatgaagttg
     7561 cagaaaaagt gggtaaacta ttaaggaggc tatcaaatta tgaaaaataa atttttttca
     7621 aatgcgccaa tccatatcat gcttatttta ggtggtattg caatggcatt accttttatt
     7681 tggatgattt taacttcagg gaaaacgttg gttgaatcta cccaaattcc acctacaatt
     7741 ttccctgaga aatttcagct aagtaactat caacaagtac ttgatttatt accattcatg
     7801 gctttttata tcaatacatt tttaatggtt gttggacgag tgattggctc ggttttattt
     7861 tcagcaatgg ctgcatatgc ttgtgcgcgt ctaagttttc cagggaaaaa tatccttttc
     7921 agcttagtac ttattcaaat gatgattccc ggttccattt ttattactcc acagtattta
     7981 ttagcacaaa aattgggtat tttaaataca attccagcat taatattacc aggggtagtt
     8041 agtgcgtttg gtacgttttt attaagacaa tttttcttag gtttacctga tgaattggag
     8101 gaagcggcct atttagaagg tgccaatatt tggacgatct ttttcaaaat tatgttgccg
     8161 cttgctaaat caggattggt tgcacttgga atattcacag cgttgtttgc atttaaagat
     8221 ttaatgtggc cattgattgt caatacttca attgataaga tgcctttagc tccgggatta
     8281 gcaaacttac aaggacaata tgccacgaac ttcccacaat taatggcagg ttcgttatta
     8341 gcaatttggc caatagttgt gatattcatc gttttccaaa gaaaattcat tgaaggaatt
     8401 gctacaacag gtagtaaatt ataaaactat taattagtga ttggagagta agtacatgac
     8461 aaaaattaca tttattggtg caggaagtac tatttttgca aaaaacgtat taggcgatgc
     8521 gatgttaact ccaagtctac aagatgcaca tattgcattg tacgatattg atgaaaaacg
     8581 actaaaagaa tcaaatttaa tgcttaaaaa tattaataaa aattcgaatg aaaatcgtgc
     8641 tgatattgtt tcttattatg atcgcaaaga agcgttaaga gaggctgatt ttgttatcaa
     8701 tgctattcaa gtgggtggtt ataaaccttc aacagtgatt gattttgata ttcctaaaaa
     8761 atatgggttg cgacaaacta ttggtgacac catggggatt ggtgggattt ttagaaccct
     8821 acggacacta ccagtaatgt tagactttgc taaagaaatg gaagaagttt gtccaaatgc
     8881 ttggttattg aactatacaa atccgatggc gatgttaacc atgggtgttt taaaagcgac
     8941 gagtattaag actgttggtt tatgtcatag cgttcaagta tgcgtaccag aattgtttga
     9001 gcatttagga atagccgatc aatatgactt aaatgacttt caatggaaaa ttgcaggcat
     9061 taatcatatg gcattcttgt tggaaattac aaaaaatggg gaagatttct atccaacaat
     9121 tcgtcagtta gctgcagaaa aaccaaatcc acatccagat tctgtacgtt ttgaattgtt
     9181 gaaacgtttt ggttactata ttacagaatc aagtgaacac aatgcagaat accatccata
     9241 ctttattaaa tcaaaatacc cagaattgat tgacgaatta gggattccgt tggatgaata
     9301 cttacgtcgt tgtgaacaac aaattaatga ttgggaaagc atgcgagagg acattgtaaa
     9361 taatggggag ttaacacata cgagaagccg tgaatatgct tcatatatca tggattctat
     9421 tacgacagga actccgtcag tgattgcagg aaatgtctta aataaaggct taatcacaaa
     9481 cttaccgaca gatgtttgtg tggaagtacc ttgtttagtc gataaaaatg gcgtgcaacc
     9541 aacctatgtc ggtgaattgc caacacaatt agctgcttta aatcggacga atatcaatgt
     9601 tcaagaactg acagtagaag ccgctttaac actagataaa tcaaaaattt atcaagcagc
     9661 gtatttagat ccacatctat catctgaatt gtctttaaca gatatcaaaa atttagtgga
     9721 tgatttaatc gaagcacatg gggactattt acctgaatat aattaaaaag aagctgaaag
     9781 agtaaggaat tttcaattcc ttactctttt cttagttaaa tttagtaaaa atattgacaa
     9841 aacacttagt aaacagttac attagtgtta acaaaaagaa aacgcattca aattgtataa
     9901 ggaggagcat aaaatgaagt ggtctaaaaa aattatttta gcttgtatag cactaggagc
     9961 aacgatctct ttgactgctt gtggaaaaaa tcaggaagat gcaagcggta aggtagaaat
    10021 agagtttttt aatcaaaaaa aagaaatgac tcaaacgatt caggagattg ctaaagattt
    10081 tgaagcaaaa aaccctgata ttcatgtaaa agttgtggat gtaccgaatg ctggtgaagt
    10141 aattaaaaca cgtatgcttg caggcgatgt accagatgtc attaatcttt atcctcaaag
    10201 tatagaattg aaagaatggg cgaaagctgg ttatttagag gacttaaccg aagaaccgta
    10261 tttagagaat atcaaaaatg gatatgcaca acgttttgct attgaggatc gtgtatatag
    10321 cataccatta accgctaatg tctatggttt ttactataac aaaactgctt ttgaggaaat
    10381 ggggattcaa gcaccagaaa cttgggcaga atttgaaaaa atagtagctg agattaaaga
    10441 tcaaaacaaa gtaccgtttg cgattgcagg agcagaaggc tggactttaa atggttatca
    10501 ccaactagct atagcgactg ctgctggtgg tgaagaggaa gcgaacaatg tttggcgttt
    10561 ctcagaagtt aatggaatta atgctgaaag caaagaaatg caaaaagatt ttaatcgatt
    10621 agatttgtta agagaaccaa aagctttgca aaacaactgg caaggtgccg gttataacga
    10681 tacagtagtt acttttacaa aaggtgatgc gttgattatg ccgaatggtt catgggcaat
    10741 gccgatgatt cattcacaaa atccagattt tgaagtagga acttttcctt ttccagcaga
    10801 tgaagcaggt caaagtctaa cgattggcgc aggagaccta gccttatcag tttctgcaac
    10861 ttctcaacat aaagaagaag ccaaacgttt tgtagaatat atgacaacac ctgaagcgat
    10921 gcagaaatat tatgatgtag atggtgcacc gtgtgctgtt gagggcgtta tcgagaatac
    10981 tcaggattca ccattaagtg gtttaactga acttgctttt actgatcgtc atttagtttg
    11041 gttagccaaa gattggaata gtgaaaatga tttttatacc ttaacaacaa attatttaca
    11101 caatggcaat caaaaagcca tgattaacgc attaaatgct ttctttaatc caatgaaagc
    11161 tgacggaagg taggaaaata aaatgaaaat aaaagaaatt ttaaatcgtt actgggcaat
    11221 catttttgta gcaattccaa ttattttgca gatgattttt ttctactttc caatggttca
    11281 aggtgctttt tacagtttaa ctaattggac tggtctgact tataattttg attttgtggg
    11341 tttgaacaat tataagattc ttttttctga tccgaagttt atcaaatcga ttggcttcac
    11401 tttaattgtg acgctttgca tgattgctgg acaaattggt tttggtattt tgattgcgcg
    11461 ggcgttgaac gcaaatatta aagggaaaac attctttaga gcatggttct tttttccagc
    11521 ggtcttatcg ggcgtggttg tttctttagt atttaaacaa atttttaact atggtttacc
    11581 aaaaattggt agtatgttag gcattgaatt tttacaaacc agtcttttag gaacaacatg
    11641 gggagcgatt tttgcagtaa tttttgtttt actttggcaa ggaattgcca tgccagtcat
    11701 cattttctta gcgggttttc aaagtattcc acaagaaatt attgaagctg ctagaatgga
    11761 tggggcgaat gataagcaaa ttttttggaa tattgaaatc acctacttat taccaagtat
    11821 ttcaatggta tttattatgg cattaaaagg tggcttaaca gcatttgatc aaatttttgc
    11881 tttaactggt ggtggaccaa gcgatgccac aacatctttg gggttacttg tttataatta
    11941 tgcttttaaa aacaatcagt ttggttatgc gaatgctatt gctttagtct tatttatctt
    12001 aattgggatt gtttcactgg cacaattaaa attatcgaaa aaatttgaaa tctaggaggt
    12061 ttcccaatga aaacatcaaa agaaaaaaat atttctaaat acttgctttt attattaggg
    12121 ggcttcatga ttttagttcc cttagtttca acgctattcg gttcatttaa aacaacaccc
    12181 gatattatga ataatttctt tcgttttcct aatccagcga ctttggaaaa tttccgaaga
    12241 ttgttagcgg atggaattgg tcattacttt tggaattcgg caatcatcac aatcattgca
    12301 gtagttgctg tgacagcaat tattcctatg gctgcttatt cactagcaag aaaaatgact
    12361 cgtgggaaag catacggatt gatgtattta tttttaattt taggaatttt tgttcctttc
    12421 caagtaatta tgattccgat taccgttatg atgagtaaaa ttggtttagc aaatatgtgg
    12481 ggattaatct tactctatct cacttatgcc gtaccacaga cactattttt atatgttggt
    12541 tttattaaac taaatgtgcc tatcagtctg gatgaggctg ctgaaattga tggggctagt
    12601 cactttacaa cttatttcaa aattgttttc ccaatgttaa aaccaatgca tgcgacgact
    12661 attattctta atgctctatg gttttggaat gatttcatgc taccattatt aattttaaat
    12721 cgtgattcta atatgtggac actaccattg tttcaatata attatacggg acaatatttt
    12781 aacgactatg gtccaagttt tgcttcctat acagtaggaa ttgtcacgat tacactagtt
    12841 tatcttgctt tccaaagaag tattatagct ggaatgagca atggagcagt gaaataacca
    12901 ataaattatt ctcattataa aggagttcat aaacttatga ttatatttga caatcacaca
    12961 caaacatttc atttacaaaa taaaaaaatt agctatctat taggaatcga agaaaataat
    13021 tatttaacgc atctttattt tggaaaaaag attacgcact attctggtgg gtatcgctac
    13081 ccccgaacag atcgttcctt ctcacccaac aatgcaaatg cgcaagatcg tttattatct
    13141 ttagacacat taccattaga atttccagga tatggacatg gtgattttag agaaccggcg
    13201 cataatatta aattaggaaa cggtagtcgt gtaaatgatt ttcgttatga tagctacgaa
    13261 attcaaaaag gaaagcccag cttagcggga ttgccagcct tatatacgga agatgatgat
    13321 gaagctgaaa cgctgattat tcaattgaaa gacgcgatta gtggattgac tttacagttg
    13381 ttctacacaa tttatcaaaa tcacagtgta attattcgtt ctacgcaatt agtaaataat
    13441 agtgataaaa cagtggagat taaccgctta gctagtcaat caattgattt tccaaatcgt
    13501 ccactcgagt taattcattt aaatggtacc tgggcaagag aacgtcaaat gactagagaa
    13561 aaaattcata cagggataaa agtattagat agtaaacgcg gatcaagcag ccatcaacaa
    13621 aatccgtttg ttgctttagt agatgccaaa acagatgaat ttcaaggaga ggcatatgga
    13681 tttaatttag tttatagcgg taatcacgaa acggtgattc aaaaagatcc atttgaccaa
    13741 acacgggtca ttatgggaat taattcattt aattttggtt ggcaactaaa aactggcgac
    13801 tcatttcaaa cgccagaagt cgtgatggtt tatagtaatg aaggtctgaa tacgttatca
    13861 cagacgtatc atgaattgta taatcaccgt ttaattcgtg gaaactatcg tttaaaagaa
    13921 cgtcccacgt taatcaacaa ctgggaagca acgtattttg attttaacga agaaaaaatc
    13981 atgaatattg tcgatgatgc gaagaacttg ggcattgaaa tgtttgtttt agatgatggt
    14041 tggtttggcg gtcgtgaaaa tgacttcact tcattaggtg attgggttga aacagaaggc
    14101 aaacttgctt gtggtttgga aaatttagcc aagcaagtgc atgataacgg gatgaaattt
    14161 gggatttggt ttgaaccgga aatgatttct gaagatagtg aactatttcg agcacatcca
    14221 gattgggcat tgggtattcc aggtcgtgac cgctcaatta gtcgaaatca atatgttctt
    14281 gatttttcaa gacaagatgt tcgtgataat atctatcaac aaatgacggc gatttttgat
    14341 cgtgtaccga ttgattatgt gaagtgggat atgaatcgaa atatgacaga agtctattct
    14401 gtcttgttgg actcaacgat gcaaggtgaa gtggctcatc gttatatgtt agggttatat
    14461 gaatttttag aaaagttaac aacgaattat ccaactattt tatttgaaag ttgttcgggt
    14521 ggaggcggtc gttttgatgc aggtttcttg tattacatgc cacaaacttg gacgagcgac
    14581 aataccgatg ccgtggctcg tctgaaaatt caatatggaa ccagcttagt gtatccaatt
    14641 tcaagtatgg gtgcgcatgt ttcagcagtc ccaaatcatc aaacaggaag agaaacgagt
    14701 ttaactattc gtggcaatgc tgcgatggct ggtgtttttg gttatgagct agatctaacg
    14761 caattaactt ctgaagaaaa agcagaaatt aaagaacaag ttgcctttta taaaaagcat
    14821 cgccaacttt tgcaatatgg aactttttat cgcttggaaa gtccgtttga aggcaatgat
    14881 actgcatgga tgtttgtctc aaaagaccaa acagaagcca tggtctttta tttccgagta
    14941 ttagcagaag ctgcgcatcc attagtcaca ttgaaattag caggattagc agaagaagca
    15001 acttatcaaa tggaagatgt aacatttgct ggcgatgaat tgatgaatct cggtttttat
    15061 attgactcag aactacatgg tgattatgcg acacaacgct tttatttgaa acagatatag
    15121 tagcttgaat ttacaatata agtgcaacac caaaagagac tcattccaaa cgaagaaaat
    15181 atgttttatt tacacgcatt tactaaaaag cagcctgatt tgaattggga aaatgaagaa
    15241 gtacgtgaag aaatctatgc aatgattaac tattggttag ataaaggact aggcggattt
    15301 agaatcgatg cgatattaaa catcaaaaaa aaactagagt atggcatctt tgaatctgat
    15361 ggagaagatg ggttagcctt cattgggccc tggattctta atcagtcggg cattgaagtg
    15421 tggttaaaag aaatgagaga gcggacattt aaaccacata atagtatgac ggtagcagaa
    15481 gccgatgttc ctaatgaacg tttagatgaa tatattggtg aagatggcta ttattcgatg
    15541 gtttttgatt ttagttatac ggatattgat gtacctgaaa ctggtgaatg gtttaaagat
    15601 agccaatgga catggacgga tatgcgtacc aatattttta cgaatcaatt agttacgcaa
    15661 gataaaggtt ggggcgcctt atatttagaa aaccacgatc aaccacgttc aattaataaa
    15721 tatattccag aagaatggat caatgattat agtaaaaaaa tgttggcgac gctttttatg
    15781 ttactaagag gtaccccttt tatttatcaa ggacaagaac taggaatgac caacatagaa
    15841 atggcatcat tagaagattt tgatgatgta gctacgcatt ctcagtataa acgggcatta
    15901 gaatatggat tggcaccaga gcaagcattg aaagctgtca ataaacgaag tcgggataat
    15961 tctcgcacac ctatgcaatg gaatacgcaa aaaaatgcca gattctcaac ttctgataat
    16021 gtatggttaa aagtaaatcc taattatcca gaactcaatg cagaagctca gttaaccaat
    16081 caacagtcgg tattcaatta ttatcatcaa ttaattaaat taagaaaaaa tagtgtatac
    16141 aaagacgtgc taatctacgg acaatttcta ccagtgaaag ataaaaatga acatattttg
    16201 ctttatgaac gccaattaga agataaaatc gtattagtta tcttaaacgt tacagcaaca
    16261 gaacaagaat attatgtaga tgaacagtac caacaagtat taatcaataa ttatgaagat
    16321 gttttattag atcaaagtcg aaaattgcgt ttacgaccgt ttgaaagtat tgtattagct
    16381 aattatggag gacaattatg aaaattaaaa acgaagcaat gctcatcacc tatgcagata
    16441 gtttaggaaa aaacatgggc gaattaaaac aagtcttaga caaacattta caaggtgtta
    16501 ttggtggtgt acatctgttg cctttttttc catcgacagg tgatcgaggc tttgcgccga
    16561 gtgattatac gacagttgat ccagctcttg gaacatggga agatgtggaa gcattaggtg
    16621 aagattatta tttgatgttt gattttatga ttaatcacat ttctcgtgaa tcaaaatttt
    16681 tccaagattt caaaaaaaac catgagcagt caccatacaa agaaatgttt atccgtattc
    16741 atgaattttt cccagaaaat cgaccaacac aagaagatat tgatttaatc tacaagcgta
    16801 aagacaaagc gccgtttcaa acggtagaat ttgcggatgg tacgacagaa gaggtttgga
    16861 atacctttgg ggaagaacaa attgatttag atgtgaccaa agaagttgtg aaagaattta
    16921 ttcgagaaac catcaaagat atggcgaacc atggctgttc tttaattcga ttagatgcgt
    16981 ttgcttatgc gattaaaaaa ttagatacca atgatttctt cgtggaacca gatatttggg
    17041 aacttttaga cgaagtgcgt caagaagcag cgaaatatga cgtcgaatta ttaccagaaa
    17101 tccatgagca ttattccatt caaatgaaaa ttgccaatca tgattattat atctatgact
    17161 tcgccttgcc aatggtcact ctgtattcac tttatagtgg aaaatcagaa cgtttagcca
    17221 attggttgaa aatgagtccg atgaagcagt ttacaacatt ggatacgcat gatggaattg
    17281 gtgttgtgga cgctcgtgat ttattaacag atgaagaatt ggattacacc tctgaggaat
    17341 tgtataaagt cggggcgaat gtgaagaagg tctattcaag tgccaattac aataatttag
    17401 atatttatca aattaacagc acctattata gtgcattagg cgataatgac cgtagctatc
    17461 tgttagcacg tgcgattcaa gtatttgcgc cagggattcc acaaatttat tacgttgggt
    17521 tattagcagg aaaaaatgat attgaactgt tggaagcaac gaaagaaggg cgtaatatta
    17581 atcgtcatta ctatgattta gccgaaattg aagaagaagt gcaacggcca gtgattcaac
    17641 aattatttgc acttttaaaa tttagaaatg aatctgcggc gtttgatttg gatggaacga
    17701 ttgaagtagc aacgccatca gaatcagaaa tagtgattac acgtaaaaat aaaaacggta
    17761 gtgatagtgc aacattaacg gctaacttgg atacgaaaga atttatcatt gagtctaaag
    17821 atataaaaat tttcactagt gttgcattaa aattttaacc tattccatag aacaaaaaat
    17881 cctttatact agcacttgga tgacttatcc aagaccaata aaaaggactc atacatggat
    17941 aagtataaaa caaatacagc atttaataaa tggttttctg ccataaaatt aggaaaactt
    18001 tctgtcaact cccaaaaatg tatttttgat tacaattcgt atcgtaaaaa actgtctttt
    18061 gaagctgtgc tcaagctctt tctctacgca gttaatgaag aaaaagaaag tttgcgtgat
    18121 ttgagtacag ctcttatcga ccgatcgctc caactagaaa ccgatgtgtc atcgattagt
    18181 catacccaat tgtctcgagc atttaatgca cttgaaccta aagtgttaga agaaattttt
    18241 caacaactgt tagaaaaagt tcaacatcaa atcaaaccaa ccaagcgaaa tcatctgtat
    18301 ctgattgatt ccagtacgtt ttcgcttagt ttaaaacgtc ataagtgggc gactttccgt
    18361 caaacaaaat caggtgtcaa gttacactta aactattgtt atatggacga tactacgatg
    18421 tatccaactg attttacctt aacaaatgcc catgaacatg atctcaatca actaccagta
    18481 ttggtgaatc aaccagaggc aacttacgtg tttgatcgtg ggtattagga ctttgaaaag
    18541 atggatcaga tgcattggga tggctatttc ttcgtcactc ggattaaaaa aaacaccaaa
    18601 gttcacgtga tagatactct ggaaacatcg ccagaaacag aaattctacg agacgagctg
    18661 gttcgtttag gatctaaaac ctatctaacc gccaatttcc gactagtcac tgttcaagat
    18721 aagaacggac gtgtgtttca atttatcacc aatcgaatgg acgtctcttc aaaagaaatc
    18781 tctgatatgt atcacgctcg ttggcaaatc gaattgtttt tcaagcacat caaacaacac
    18841 atgaccatta aaaccttctt ttctcaaagt gaaaaaggcg tgcagaatca attgatttta
    18901 acgatgattt ccgctctcct cacgtttctc atcaaattgg agacgaaaac ggaaaaatca
    18961 gtgttccaaa tcaaacgatt ctttcgttat ttactgtttc agccctttga atgttgtcta
    19021 gaaaaattaa ttcccacatg agaaaaaaga aatttggctc gttacttttg gttttcagtt
    19081 gaataacaga taaaaaattt tctggaaaaa gtcatcctct gcgtcagcac agtttttttt
    19141 gacttatttt cagaggaaat agttttcaga atattctaaa atgttttatg caacactagt
    19201 gatatttttt agaattagat ttctaatgtg cattttttga gtattaagga gcaagtatac
    19261 aaagatttat aaagctgatt aaatttgaat aaaaatatgc aggaacgcta ct
//
LOCUS       DACDLM010000056        19294 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.056, whole genome shotgun sequence.
ACCESSION   DACDLM010000056 DACDLM010000000
VERSION     DACDLM010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.056"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(47..1426)
                     /gene="brnQ"
                     /locus_tag="IV356_002018"
     CDS             complement(47..1426)
                     /gene="brnQ"
                     /locus_tag="IV356_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAP9015685.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMPLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            2132..3103
                     /locus_tag="IV356_002019"
     CDS             2132..3103
                     /locus_tag="IV356_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HAP9015686.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            3127..5319
                     /locus_tag="IV356_002020"
     CDS             3127..5319
                     /locus_tag="IV356_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HAP9015687.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            5336..5812
                     /gene="ybeY"
                     /locus_tag="IV356_002021"
     CDS             5336..5812
                     /gene="ybeY"
                     /locus_tag="IV356_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HAP9015688.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            5790..6191
                     /locus_tag="IV356_002022"
     CDS             5790..6191
                     /locus_tag="IV356_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HAP9015689.1"
                     /translation="MPMDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFG
                     ILALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKD
                     MAAGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            6206..7105
                     /locus_tag="IV356_002023"
     CDS             6206..7105
                     /locus_tag="IV356_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HAP9015690.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            7248..8060
                     /gene="recO"
                     /locus_tag="IV356_002024"
     CDS             7248..8060
                     /gene="recO"
                     /locus_tag="IV356_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HAP9015691.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            8444..9361
                     /gene="glyQ"
                     /locus_tag="IV356_002025"
     CDS             8444..9361
                     /gene="glyQ"
                     /locus_tag="IV356_002025"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HAP9015692.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            9363..11438
                     /locus_tag="IV356_002026"
     CDS             9363..11438
                     /locus_tag="IV356_002026"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HAP9015693.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKITNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDIKTDRASRGHRFLGEDVTFTHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKNHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLNQIAAMALSL
                     ASLDQIITK"
     gene            11828..12607
                     /locus_tag="IV356_002027"
     CDS             11828..12607
                     /locus_tag="IV356_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015694.1"
                     /translation="MEKPFVKSLTAVAVGAGAIVICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKIFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVIIKEKVT
                     SADVARVRENMSFFKDSPWKTVVIQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISVAYATKAQTVAQQMGYSNISY"
     gene            12653..13597
                     /locus_tag="IV356_002028"
     CDS             12653..13597
                     /locus_tag="IV356_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP9015695.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGSDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            13613..14392
                     /locus_tag="IV356_002029"
     CDS             13613..14392
                     /locus_tag="IV356_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HAP9015696.1"
                     /translation="MEETISLKEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKRTAPARPKATNDKTAPSRRSRSRV"
     gene            14404..15102
                     /locus_tag="IV356_002030"
     CDS             14404..15102
                     /locus_tag="IV356_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HAP9015697.1"
                     /translation="MARTQKQKATQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAS
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENMSRKESLTKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            15130..15894
                     /locus_tag="IV356_002031"
     CDS             15130..15894
                     /locus_tag="IV356_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HAP9015698.1"
                     /translation="MIDLHCHILPGIDDGSENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKEFG
                     KEKVVQMKQVAKDLINGDEINYPIYEEVKKKKFGLF"
     gene            15908..17727
                     /locus_tag="IV356_002032"
                     /pseudo
     CDS             15908..17727
                     /locus_tag="IV356_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008378780.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
     gene            17738..18370
                     /locus_tag="IV356_002033"
     CDS             17738..18370
                     /locus_tag="IV356_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAP9015699.1"
                     /translation="MKAIIIGAGGFGKEIAFLLQSVSRYELIGFVDDSLKMKNQELLG
                     KPVLGTIDSLIELEEETAIFLGIASPDIKEKIYQKINKNNKLIFPNLVAPSALVGINV
                     QLGIGNILMPYTTYTADVVLGNFNMINIGSTIGHDAQIGNYNSIFPSVNISGHVILGD
                     KNEIGVGTKIIQNLRIGNMNIIGAGSVVIKNINNNTKNVGVPTKVIERWD"
     gene            18372..>19294
                     /locus_tag="IV356_002034"
     CDS             18372..>19294
                     /locus_tag="IV356_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HAP9015700.1"
                     /translation="MENKRILLASPHMSEEGYEQEYVKEAFDTNWVAPLGANVNGFEK
                     ELAKYVGASHAAALSSGTAAIHLALKAAGVGKDDIVICQSLTFSATANPILYQGAIPV
                     FVDSDYETWNMKPEHLRTALEKYPNTKAVLVVHLYGLSANLDEITKICKEYDVTLIED
                     AAESLGTTYKGKYTGTFGDYGIYSFNGNKIITTSGGGMLVSNDKEKVEKVRFWATQSR
                     EKARHYQHNEIGYNYRMSNIVAGIGRGQLKVLNERIEKKRYIHSFYKNELSKLSNIQF
                     MPENNWNEPNYWLSVITIKGINTNHLIDELD"
BASE COUNT         6630 a         3417 c         4019 g         5228 t
ORIGIN      
        1 ttttttcctg tttaatatct cttatgttaa attgtgtttg atttggttat tcttctggta
       61 gttcatttgc ttcttgttta taccctgata ggcgataggc gtaataaaag agtaagctgc
      121 cagcgtaacc aagtaacgtt gggaccatcc agccaagtcc taatgcagca aaaggaacgt
      181 gatgatgata aaatcctagt aagcttgcta cgacagtttg ctgactcact aatgcaggcg
      241 aatttgccaa catatccaat acggctggaa cggcagaaaa gaacatcgtt acttgataga
      301 caaatggact cttttggaag aattttgctg ttaaggaaag caagattaac gcaagtgaca
      361 atggatacaa aagcatcaat actggtaaag accattggat gatattatcc aatccggcat
      421 tcgcaacgac aaaagagaca aaagtcgtta accgcagcca tgtcatataa ctgactttag
      481 ggaacagttt atggaaatct tgtgcaaaag aaacaacgag tcccatagcg gtagtgaaga
      541 cacctaatgt gaccattacc cctaagaagc tagcaccgaa gttacctaaa taaaaattag
      601 tgatctgaga aagtgcagtt ccgccatttt ctgataaagg catcttattc aaactcatcg
      661 caccgagaag gaccagacca aaataaatca tgacttctaa cgcaacgctc aggctaccag
      721 cttttgctgt taattctgtg acttttttat ctttaaaacc aagatcacga actgcatgga
      781 caaaagtgac acttaaagca agtaaagcta ctgcatcaac cgtgttgtat ccttctaaaa
      841 cgccatttgt caaagcgttc gtctgataag aatctgcagc agattggttt agattcccca
      901 tgggttggaa taaagaaacg acaaaaatga tagctaataa tgcaagaaac aaggagttta
      961 aatactttcc gacatatttg accaaacgtg ttggatgtac agtaaggaaa taagcaagta
     1021 aaaagaaaag agcagagaat aaaaacatac ctaatgaatc atatttttca ggcaaaaagg
     1081 gtttagcagc catttcaaaa gcagttgctg ctgtccgcgg tgtaccaaag aatggtccga
     1141 tcgttaaatg aacaaggatc aagaacaagg cagcatacca ttttccgaca ggtttagcta
     1201 agtcatacag accatcactt tttgtcacta ctacagctaa gatagctaat aatgggaaaa
     1261 gagcgcctga gatggcaaat cctacaccag cgctgatcca gtttgatcca gccatttgac
     1321 ctaagtggac aggaaagatc agattacctg acccgaagaa catcccgaag ataagtgaac
     1381 tgaccatcaa taattgcttc catgaataag tttttgtttc ttccataaat ttttcctcca
     1441 ataattatca ttttgagtaa caaaataaac gttgcagaaa ctagaaatgc cactaatatc
     1501 agattccatg aaaaccacca ccttaaaata taaaaaaaag cccttttcca cttgggaaaa
     1561 gggctctaga ttctagaacg gtaccacctt ttttcgctta aaaaagcttc ttcattcacg
     1621 gacgcttttc gataaagtta tccgctagcc tgataatgga ggcagccaca atgatctacg
     1681 ttttcgacat tgactcggaa atgatgttcg tctattcgat ttattgtcat ttctcactta
     1741 catgactcac tgggaataaa tcgctgaata gcctactgtt ttcctcgacg ctttgctgta
     1801 tatttatttg ttgacgttat aatacacctg ttttttttga aatgcaagaa tatttcaaat
     1861 attttgtttt ctttttttga aacaagaaaa atacccagag aatacttgct aagttagacg
     1921 gaatacttgt cctctatctt atgcatagct tacatgatca gcttttttta ttcaaacgag
     1981 acctttagag aatggaagca gctatttttt aacgtttctt ggtacttatg gttaagcaac
     2041 tcttttagaa ccttttctta tttgctatat agtttcttct gagtatggta aaataggaaa
     2101 gaatgaatcg aaaaaaaggg gatgtctatt tttgacggaa gagtctagtt ctttagagat
     2161 tagattgacg gctgctgatg atgtcagcat gcttttaggt gcacacgaca agcatataaa
     2221 actgattgaa gaaacaacag aaacaaccat ccatacacgt ggagaaatca ttcagatcat
     2281 tggcgaacaa tcccagattt ccttggctgc ctcagtcatt cggacattgc aggaattgat
     2341 caaacgagga atccatgtaa gtacaccaga tgtcgtgacg gcactgaaaa tggggcaaaa
     2401 aggcacatta gattattttg ttgaaatgta tgaggaagag atcgtcaaag accgtaatgg
     2461 aaaaccaata cgggtaaaaa acagcggcca aaagaaatat gtcgaatcgg tagccaaaca
     2521 tgatatcgta tttggcgtag gaccagccgg gacaggaaaa acttttcttg cagtagtatt
     2581 agcaatcgct gccttgaaaa aaggtgaagt gcaaaaaatc attttgacgc ggcctgctgt
     2641 ggaagcaggg gaaaatctag gctttcttcc cggggatcta aaagaaaaag tagatcctta
     2701 tctgcgtcct gtttatgatg ctttatacca aatttttgga ttagatcata cgaaccgatt
     2761 gatggaacga ggcgtgatcg aaattgctcc tttagcttac atgcgggggc ggacattgga
     2821 tgatgcattc gttattttgg atgaagcaca gaacacgaca gttgctcaga tgaaaatgtt
     2881 cctgacacgt cttggttatc aatcaaaaat gattgtcaat ggagatacga gtcagattga
     2941 tctgcctcga gggacaacaa gtggtcttgt tcatgcagaa cgaacattaa agcaaatcaa
     3001 gaaaatcgat tttgttaatt ttgaagcaag tgacgttgtt cggcaccctg tagttgccga
     3061 aatcatcaaa gcttatgaaa aggcagatct ccatcaagaa taagctttgc ttaggaggat
     3121 aagcacatgt tgaataaaac actgcagaaa ctacaagaaa aacttggaaa ggcagcattg
     3181 cctttcctgc tgttcttgtt ttttatcatt atctgcggcg ttacatttag tagtgtcaaa
     3241 caaaaggcca atgatttcag agaaggccaa gtagcagaag aaagtatccg tgcgaacaaa
     3301 acgatcgaga acacggaaga aaccgaacaa aaaagaaaac tggcagcaga agcagtcact
     3361 ccagaataca cttaccaaaa agatcttgca gatgaccaga acaatcggat caagcaacta
     3421 tttgaattga tcgataaaac gaatgatgcc atcaacaaat cttatgacga aaagattgat
     3481 aaggcaaagg aagatgaaaa tatcccaaag cctactacag aagagcggat cgccgcgttg
     3541 aagaaaaatt ttgaaaatgt gaatgcagaa aatgttgcgt tttatcaaaa actaccgaac
     3601 aatttttatt cgacgatatt tgaaatgact gaaactgaga tccatactgt gagggatgag
     3661 agtctgaagc tcattgacga acagatgagc aaacaagttc gtgaaagtga attggaagct
     3721 tttaaacaag aagcagaaga gcaaatccaa tatttgaatg tcacaccagc acaacaacaa
     3781 atgattcgct acttagtgga tcaaggtatc gtagtgaatg acgtattgaa tgagaaaaag
     3841 acagaagaat tgaaacaatc cgcacgagaa gctgtacaac cagtgatgat cttccaagga
     3901 gaaatcattg ttcgtgaagg taatcaaatc gatgcttcag ctatgaaaaa attggaatta
     3961 ctaggactga ctaatcaaac aacttcgatt tttccgctaa ttgccatggt tttagctgtt
     4021 ttgcttcaaa tcggcgtact gatttataat tcacttcaat tccaaaatgc aggagaaaga
     4081 acaaaatacg tgcttttcta tgtgacagct atgtcagtca gcatagtgct gatgaaattt
     4141 ttccaattat tccaaacgga acaagctact tatatcccgc tgttttatcc cgctgctttt
     4201 gcaccacttg ttttaagctt tttcttgaac cgaagagcag ggatcatggc tggtattttc
     4261 caagcagtat ctgcactttt cattttttat gattcgattg gcacgaactt tctaacgatt
     4321 atcttgatgt cttatgtttt ctctgggctc atggcaacga ttgtcagacg caaacggatc
     4381 tcagaacaag gattatctgc tgccatgtgg gtcattattt ttcctgtgat gatggatgtc
     4441 attttgatcg tctatcaagg aatgagcttt ggtgatgcaa cgacttggtt aatgcttgtc
     4501 tgcgggttca ctggtgcact cttctcattc ttgctgacga tcggtctaca cccatatatt
     4561 gaattgatgg tcaatgatga cagtgtaatt gtattaaatg aactcagcaa tccaaatcat
     4621 cctttattga aacagttgct ggaagaagcg ccaggtactt atcatcatag tatgatggta
     4681 gctaatctaa gtgctaacgc tgtagcagaa atcggcggac gttctttgct aactcgagta
     4741 gcttgctatt atcatgatat cggcaagatc aaacatgcta gctttttcgt tgagaacttg
     4801 ccttcaggag cggaaaaccc gcacaatttc ttattgccag aagacagtaa acatattatc
     4861 tttggacatg tgacagatgg agccaaaata ttggaagatt ataatatgcc gcaaatggtg
     4921 atcgatattt gcaaacagca tcatggaacc acgctaatgc gttatttcta catcaaagcg
     4981 aaagaacgca atccggaagt aacagaagag caattccgtt atcctggacc aaaaccgcaa
     5041 agtcgtgaag cagggatcgt caatattgct gacagttgtg aggctgcagt acgggcaatg
     5101 gatcatccga cgagcgaaaa aatcgaaagt tttgtccata atcttatcga agagcgtatt
     5161 tccgatggtc aattagacga tagtggactg accttgaaag aaatccgaaa agtggaaaaa
     5221 tcattgatca gcggtttaag tagcaccttc cattctcgga tcaaatatcc taaaatgaaa
     5281 acagaagttg agaagataaa ggaagaacaa gaagaataga aagaagcgat gtataatgga
     5341 tattaccttt atggatgaaa caaaccaagt ctcagaagag aaaatgaaag aaatcgatga
     5401 cttgctgcaa tttgcagcat cttatttaaa gctgccagag gaaacagaaa tgtctgttac
     5461 tttcatggac aatgcggcaa tccaagtaat caatcgtgat taccgtggaa aagatgcacc
     5521 gacagacgtc atcagttttg ctctggaaga agaaggcgaa gacgaaatcc cagtgatttt
     5581 tgaagatgga gagaatccat tgcctcgtgt actaggagac atcatgattt ctattgaacg
     5641 tgctgctgaa caagcagaag cttacggcca ttcatatgat cgggaacttg gctttttagc
     5701 ggtacatgga ttcttgcata tcaacgggta tgaccatatg acaccagaag atgagaaaga
     5761 aatgtttggt ttacagaaag agatcttgga tgcctatgga ctcaaaagat aaaaacgtag
     5821 agaaaaacaa acatttcctg atgtctgtgg aatttgctgt ccaaggagtc aaaaccgttt
     5881 ttgaggaaga acgcaatatg aggaaacatg ttgcgttcgg tatccttgct ttatttatgg
     5941 gcgtgatttt ccagcttgat cggatagagt ggttatggct gcttttagct gtttttctcg
     6001 tttggatagt agagatcatc aatactgttt ttgaaaatgt agtggacatg tttacggatt
     6061 ttcattttca tccgattggg aaaaaaatca aagatatggc agctggagca gttttagtga
     6121 ccgcttgttt tgctgtcatc attgggttga ttttatttgt ccctaaaata tatcatttgt
     6181 tgtttaatta aaaaggagaa cgtatatgcc agaacataaa tcagggtttg tcgcaatcgt
     6241 cggccgcccg aatgtaggaa aatccacatt attgaaccga atcgtgggtc aaaaaattgc
     6301 cattatgagt gacaaggcac agacaactag aaataaaatc caaggagtat atactacacc
     6361 agaagctcag ctgattttta tcgatacacc aggaatccat aaaccaaagc atcgtctagg
     6421 agattttatg gtagaagcag cttacagtgc gttgaaagaa gtggatgcag tcttatttat
     6481 gatcagtgct gatcaaaaac gcggccgggg agacgatttt attattgaac gtctaaaaaa
     6541 cgtgcattct ccagtttatc tgattatcaa taaaatcgat aagatccatc cagacgagtt
     6601 gctgggaatc atcgaagatt attcgacgca gatgcctttt gcacaagtga ttccgatctc
     6661 tgctacagaa ggaaacaatg tcgaacgctt aatggatgta ttagtcagtg aaatgccaga
     6721 gggcccacaa tattttccag atgatcaagt gactgatcat cctgaatact ttatcgtttc
     6781 tgaattgatc cgtgagaaag tcttgttttt aacacgagac gaagtgcctc attctgtcgc
     6841 agtcgttgtt gattcgatga agcgaaacga gaatgataaa atccatatcc aggccacgat
     6901 catcgtcgaa agagatagcc aaaaaggaat cattatcggc aaaggcggaa aaatgctgaa
     6961 gcaagtagga acgaaagcaa gaaaggatat cgaaaatctt ttaggagaca aagtatttct
     7021 agaactttgg gtcaaagtcc aaaaagactg gcgagacaaa aaagtctatc tgcaagactt
     7081 tggctaccga aaagacgaat actgatattc tgaacttctt ataggttaag tatagaaata
     7141 aactggataa aaatccgcac gttgagaaaa acggcggaag atcgaaacat aaataatctg
     7201 gatcggcaga atctgctttt ccagatttat tttttaggag ggagaatatg agccagcttg
     7261 cagaatcgaa aggcttgatt ttatctagcc gtaattacaa agaaaaagat aaattagtca
     7321 aaatctttac ggaatcttct ggcaaaatga tgttttatat caaaggaatc catcggcaaa
     7381 atcagccatt agctccggct ttgctcccct ttaccgaagc agtctatatc ggtaattttc
     7441 gaagtgaagg tttgtcgttt ttaagcagtg tcaaagacgt ccatgcgttt cggaacatcc
     7501 aagaagatat ctttttgagc ggttatggta cctatttgct aaatctagta gatgcagcaa
     7561 tcgaagatca tcaatatgac ccgcatttat tccaatttac gcaacaagct ctgcagcgga
     7621 tggatcaagg agatgatgca gaaatcatca cgaatatctt tgaagttcaa atactgcaac
     7681 gcttcggaat cgcgccaatt tggacgcact gtgtcgtatg cggggaaaca aaaggaaaat
     7741 ttgactattc ttccaaatat ggcggtgtga tatgcgagaa acactggcca atggacgaac
     7801 accgttatca tgcagatcct cgcgctgttt atttcgttcg aatgttttcg gctatttctt
     7861 atgataagat cagtggaatc cacttgaaag aagaaacgaa gcaggcaatc cgtgacctca
     7921 ttgaccagtt gtatgatgaa tatgtcggta ttcatctaaa aagcaaaaag ttcattgatc
     7981 aaatgaagtc ttgggcacac gtattaaaga cgccagagaa aaatatgcct gaaaaagaga
     8041 tacctgaaaa agaagaataa atgaaagata caacaaaaaa atcaaaacta tttgacaaat
     8101 acagggactt ccgtctatta ttaaccgtag attaaataga tcgttcactg agaggatcta
     8161 ttatataaac aagaaaactg caaaatgaat acgtacattg accaagatca gtaaaaaaca
     8221 cgtggtttag cgagttcggg agagtggaag ccggacccaa acgatttttg aagaggcact
     8281 tgcgagtacg ataaatgaag ctgccgaatc tttattcgga agtagggtgg aaccgcgaaa
     8341 ttattcgtcc ctatgtctgt aatcagacat agggactttt tgtcgttttc tttcctgtat
     8401 tcttattgac agcaacgctt aaaaattgaa aggggcaaaa cagatgagta aaaaattgac
     8461 cgtccaagat atgattttaa cattacaaaa attttggtca tcaaacggct gcatgctgat
     8521 gcaagcttat gatacagaaa aaggagcagg tacgatgagc ccatatacat tcttacgggc
     8581 aatcggaccg gaaccatgga atgctgctta tgtagagcca tcccgccgac cagctgacgg
     8641 gcgttatggc gaaaacccaa accgtttgta tcagcatcat caatttcaag tcgtaatgaa
     8701 accttcacct gaaaatatcc aagagcttta tttagaaagc ttgcgtcttt taggaattga
     8761 tccattagaa cacgatattc gttttgttga agacaactgg gagaacccat cgatgggttg
     8821 tgccggtgtg ggctgggaag tatggcttga tgggatggag atcacacaat tcacgtactt
     8881 ccagcaagtc ggaggactac cttgtaaacc agttacttct gagattactt atggactaga
     8941 acgtcttgct tcatatattc aagaagttga aagtgtctat gatctggaat gggctgatgg
     9001 tgtgaaatat ggcgagatct tcaaacaacc agaatatgaa cattccaaat attcttttga
     9061 agtaagcgac caagacttgc tactaagcaa ttttgaccgt tttgaaaaag aagctaaacg
     9121 ctgtatcgat gaaaatcttg ttcatccagc gtatgattat attttgaaat gcagccatac
     9181 attcaactta ttagatgctc gcggtgcagt atccgtaaca gagcgtgcag gttatctttc
     9241 ccgtatccgc aacatggctc gtgctgtagc caaaatcttt gtggcagaac gcgaaaaatt
     9301 aggattccct ttattgaata aaaacacagc aaatccagaa aacatgaagg aggctgaata
     9361 agatggcaaa agacttatta cttgaaatcg ggctggaaga aatgcctgct catgttgtca
     9421 caccaagcat gaaacaacta gaagaaaaaa cagcaaaatt tttagatgaa aaccaattga
     9481 cttatgatac gatcgaaacg ttttctacac cgcgccgctt agcaatcaaa ataacaaaca
     9541 ttccagaacg tcaagcagac agtgaagaag aagtcaaagg accagccaaa aaaattgctt
     9601 tggacgcaga tggaaactgg acgaaagcag ctgaaggatt tgtccgcgga caaggtctga
     9661 cgacagatgc tatcactttt agagaattaa aaggcgtgga atatgtctat gtaacgaaat
     9721 acactcacgg caaagaagca aaagaagtat tgacaggttt agcagatgtc attaaaagcc
     9781 tcactttccc agtaacgatg cattgggcag aatacgattt tgaatatatc cgccctattc
     9841 actggatcgt ggcattgtta gatgacgaag taatcccgtt tgagatcttg gatatcaaaa
     9901 cagacagagc ttcaagaggt catcgtttct taggtgaaga tgtgacattt acgcatgcaa
     9961 aagaatacga agaaaaatta aatgaacaat ttgttattgc ttcaccgcaa aaaagaaaag
    10021 aaatgatcat cacacaagca aacgaattag cagaaaaaaa tcactggatc attgatctag
    10081 atgaagattt actagaagaa gtcaacaatc tagtcgaata tccaactgtc ttttctggcg
    10141 acttcgaaga aaaatatcta tctgttcctg aagaagtact agtcacttct atgaaagaac
    10201 atcaacgtta tttcgaagta cggaacgatc aaggtatgtt gcttcctcat tttatttctg
    10261 ctcgtaatgg cgatcgggta aaattggaaa atgtggtacg aggcaatcaa aaagtattga
    10321 ctgctcgttt agaagatgcg gaattctttt ataatgaaga caagaaagct tcaatcgacc
    10381 aatacgttga aaaattaaaa actgttactt tccatgaaaa aatcggtagc atctacgaga
    10441 aaatgcaacg ggtacaagtc atcgctcgca tcataggcga acaagtagga ctatctgagg
    10501 aagaattgat ggatctgcaa cgcgctgctg aaatctataa atttgatcta gtaaccaaca
    10561 tggtaggaga attccctgaa ctacaaggga tcatgggaga aaaatatgct ctgcttaaag
    10621 gcgagaaacc agccgtagca acagcgatcc gtgaacatta catgcctata tccagtgaag
    10681 gagatctacc tgagactaca gtaggttctg ttttagcgat tgctgataaa ttagatagta
    10741 tcttttcttt ctttgcagtt gggatgatcc caagtggctc aaacgatcca tatgctttgc
    10801 gccgtcaagc atatggtgtt gttcgaatca tcgaatcgaa aaaatgggcc tttcctttgt
    10861 ctgttctgca agaaacgatt agtgaagtta tcagtaaaga tacggatcgt tttggcattg
    10921 gcttgtcagc gggacaacaa caggtgatcg actttatcaa aggccgtctg cgccaattat
    10981 tgacaacgaa gaatattcgt catgatgtca tcgaagctgt tttgaacgca gaacaaaaag
    11041 atctgacaaa agtatttgca gcagcacaat tgttcaagca gcatcttgca gatgaagact
    11101 tcaaaccatc gatggaagct ttgacacgtg tcgtgaactt agcgaaaaaa gcggagcttg
    11161 aaaaacaatc agaagtagac cctgaactgt tcgaaaacga agcggagaaa gaactgcaca
    11221 aagcagtaga ggcaatgaaa acaagctttg ctgaccaaac gatcaacgaa aattatgatc
    11281 agcttgtaag ccttcgccca ctgatcgaaa attattttga tcagacgatg gtcatggcag
    11341 aagaaccagc agtacgtaag aaccgattaa cgcaattaaa tcaaattgct gccatggctt
    11401 tgtcactagc aagtttagat caaatcatca caaaataatt tctaatatgt aaataaacca
    11461 gagaacaggc acaaaatagg ctatttctct ggtttatttg ttataaatat aaataactat
    11521 tattaattca atgttaattt ttttgttatt ttattttttg tgtaactttt aaaaacaact
    11581 atgaaaatta aggaaataaa aatgaaatcg attaattgtt atcttattaa tgttttattt
    11641 acttttaaat cgtaaattgc cctagtcaag aaaacagttt gtggtatgat tatatagaga
    11701 aaacttgttt ataaatattt ctgtgaatat attagtttaa ttatgttttt taaaataaaa
    11761 agctgtgatt tttatgtaag tgaattatat cttaatttat ctatcatcaa tacttaggag
    11821 tgaatctatg gaaaagccat tcgtcaagtc attgactgct gtggcggtag gtgcaggtgc
    11881 tattgtgatc tgtttgtttg gttaccatat caataatcag cggcaacatc agcaacggat
    11941 caattatgca gaatctgcca tcaccaatca aaaagacacc ttgacttctt tatcgaaaga
    12001 agtagacaag ctgtatagta caaaagaaaa aatttttcta aaccctgaaa taacagaaga
    12061 aacaattaca agtttgtcca ataagctatc ctctgtcaaa ctttcagcag atgattacga
    12121 catcaaagaa tcagaattgc ctaaagaagc tgttgcaatc caagatgaga agaaagcaat
    12181 cgtgacacag ttagatagtg cagaatcaaa actgaagatc cagacagctg tcaacgattt
    12241 atttactaaa aatgtatcaa actggcagca agctgtagac gatgtcatca tcaaagaaaa
    12301 ggtgacaagt gcagatgtcg ctcgtgtacg tgaaaatatg agctttttta aagatagtcc
    12361 ttggaaaacg gttgttatac aatatctagg attcgctgat acccagatcg cgcaagtcac
    12421 gcaactagat cagttattcg atacgatgtt aaaggatggt caagtgactg ccaccgctac
    12481 ttacgatcaa tatttgacgg cgctcagtca aatagagcag atccggaatg aaaaaataag
    12541 cgtagcatac gcaacaaaag cacaaactgt tgctcagcaa atgggctata gcaatataag
    12601 ctattgacag ttaaagcgtt gattcaagca aggttagcaa acggaggaaa ctatggcaag
    12661 acgaagaaga aaatcaagag ggaaaaaaat atttctgatt attttagcag ttcttatcgt
    12721 attagtatta gcaattgtag gagtaggagc aaaattatat ctggatctct cacattctat
    12781 tgagaaaact tacgaatcag tggaacgaac ccaaggagaa cgaacgaaac cagttgatct
    12841 ggacaaacaa gaatctttct ctgttctatt gatggggatt gatactggag atttaggtcg
    12901 ggtcgatcaa ggaagatcag atacgatgat ggttgccaca gtcagtcctg aagacaaaca
    12961 gacaacgatc gtcagcattc ctcgagatac gtatgtcgac atcgtaggta gtgacacaaa
    13021 agacaagatc aaccacgctt acgcattcgg cggagctgcc atggcgatgg ataccgtaca
    13081 aaaatatgta gacatcccaa tcgatcacta tgtctctatc aatatgaaag ggctaaaaga
    13141 acttgttgat gcagttggtg gtatcgaagt caataatgac ctcactttct cacaagatgg
    13201 ctatgacttt acaatcggta aaattacttt gaacggggat caggcattat cttattctcg
    13261 tatgcgttat gaagatccaa acggtgacta tggtagacaa gagcgtcaaa gaaagatcgt
    13321 agaaggtgta gcgaaaaaag tattgagtct aaacggtgtc agcaactatc aatccgtttt
    13381 gaatgctcta gagtcgaata tgaaaacaga catgagcttt gatgaaatga aaaaaattgc
    13441 tttagattat cgggaggcat ttggtacgat caagcaagat cagctgcaag gagaaggctt
    13501 catgcaagat aatatctcct atcaaaaagt cagtgatcaa gaacttgatc gtgtgaaaaa
    13561 agaattaaaa gatcaaatga atctagagaa taaataggaa agtggagaaa aaatggaaga
    13621 gacaatcagc ttgaaagaaa tttttgaaac attacgcaaa cacttggtaa caatcatcat
    13681 ctcaatgttt gctggcttgg ccatctcagg aatcgtaaca tttttcatct tgacaccaaa
    13741 atacagttca caagcacaat tgatcgtgac actgccacaa tcagacacag caaatgtcaa
    13801 tgatgtcaat acgaacctgc aaatgatcaa tacgtataaa gatatgatcg tcagtgattt
    13861 agtactaaat gaagtcaaag atcgtttaga aacagaagac aatgtgaaaa tgactgctgg
    13921 acaaatcaaa gatgcgatct ccgtcaatca gtcacaaaat tcacaaatgt tctcgatcca
    13981 ggcaataagc acgaatgcag tgactgctca acagatcgct aatacaactt cacaagtttt
    14041 ccaagaaaac gcaaaagacg tgatgaatgt cgataaaatc tcgattattt caggtgcagt
    14101 tgccaatacg acacctgttt cgccaaataa taaattgaat ctagtgattg gcttagtatt
    14161 aggaatgatg gtaggcgtag gtttggcatt cttattcgaa ttacttgatc ggacagtgaa
    14221 agatgaaaaa tatgtgacgg atacattagg attcccaatc ttaggaacag ttccagaaat
    14281 gtcagcgaaa gaattgaacg ctggtatccg taaaaaaaga acagctcctg cacgaccaaa
    14341 agctacaaac gataaaacag ccccatcacg cagaagccgc tcaagagtct aggaggaaga
    14401 aaaatggcac gaacacagaa acaaaaagca acacaaactc atgcagtcag tttgatcaca
    14461 ttaacaaacc catcttcacc aatcgccgaa caatatcgta cgatccggac gaatatccag
    14521 tttgcctccg cagctggtca gcaaatcaaa acgattgtcg tgacttcatc aggtcctgga
    14581 gaagggaaat ccaccactgc agcaaacatt gcagtcgttt ttgctaaatc cggtcaacga
    14641 gttctactag tcgatgcaga tttacgtaaa cccgtcgtct ataagacatt ccagttgaac
    14701 aatgccagtg gattaagtac agcacttagt tcatcaggaa gtgtagcaga tgtgatccaa
    14761 cgaacgccag tcgagaactt gtcgattttg cctagtggac ctaagccacc caacccatca
    14821 gaattgttaa gctcgccaag aatggatcag atcctagctg aagcaagaca gttatttgac
    14881 gtggtgatat tcgatatgcc accagtagta gccgtaacag atgcacagat catgtcttca
    14941 aaaacagatg gcactttatt ggtcgtacgt gaaaatatgt cacgtaaaga atccttgact
    15001 aaagcaaaag aactgctaga gatggtacaa gcacgagtct taggtgtcgt atacaacgga
    15061 gcagaacaca gcaaagatgc tggttattac tacggaaatt aaggaataag aagagaggag
    15121 acaagagaaa tgatcgatct acattgccat atcctaccag gaatcgatga cgggtcagaa
    15181 aacttagaag caagtattgc aatggctgaa aaagcgattc agcaaggcat tacgcatatt
    15241 ttatgcacac cacaccacaa taatggaaaa tacagcaatg aaaaatcaca agtcatttct
    15301 ctagtcgctt cgttacaagc cgaattagag aaaagacagt tgcctttgac gttattggaa
    15361 ggacaagaag tacgtattac cggaacgctc atcgaagaca tccaccgaga tgaaatttta
    15421 tttacagatt tagatgatac atatcttctg atcgaatttc cgacactgga agtgccttta
    15481 tatgcagaac ggcttttttt tgagttgtta gaactaggaa agacaccagt gatcgtccat
    15541 ccagaacgca acgcgcattt tcgagaagac ccaaatcatt tgcttccgtt cctagatatg
    15601 ggatgtttgg cccaacttac tgcgccaagt tatgttggtg tatttggcaa agacatccag
    15661 aaaacagcca aaacaatggt caaacataat ctcgtgcaga tggctgcttc tgatgcacac
    15721 ggggtctcta agcgcacctt ttacttaaaa gagtgctatg agcagattgc caaggagttt
    15781 ggtaaggaaa aagtagtaca gatgaaacaa gtcgcaaagg atctgatcaa cggggatgag
    15841 atcaattatc caatctatga agaggtaaaa aagaagaagt ttggtttatt ttagggggag
    15901 ttaaaaagtg tttatattaa caagaagaag aaaaattgcc acattggttg ttgtggacag
    15961 cttgttatta atcgctgcaa atattgcagc agctaaattc atgaagccgt ttgtatctat
    16021 accaatggat cttattttaa tctctatcgg tttgtcgatt ggtttttatt tattttatgg
    16081 tagtttattc aaagttttca ctcggatcaa tcgctataca aatttaagag agatcattgc
    16141 aatttttagt tcactatctg caagtgctgc ctcaagtatc ttcatactgc tgtttattaa
    16201 tcggcgatac agtttacggt tagttatctt tacttatctg ctttcgctct tattgatcat
    16261 cggtagccga ttgatctggc gtatctacat cgaaaaaaaa aaaatatgag atatgtatca
    16321 gcagattctg ctaaaaatac attgattgtt ggtgctggcg aaggcgggcg tattttatac
    16381 aacagctttc ttggatccaa aacggctcaa gatatccacg ttgtcgggtt tgtagatgat
    16441 gatccaaata aaagaaatac gtatctttca ggaaaaaaag tattaggtgc attaaaagat
    16501 attccggaat tgattgaaaa atatgacatt caaatggtaa cgatcgctat cccttcctta
    16561 tcaagaaaaa aattacgacg aatcttcgag ttagtcgaat ccgctcgtgt gaaagtcaac
    16621 acgatgcctt ctatagaaga acttgcttca gggaaaatta gcgtatcaaa attaaaaaca
    16681 attgacgtag tggatttact gggaagagat gaggtaaagc tggatattga atccatcaaa
    16741 gatcagatca cagacaaagt cattcttgtc accggcgcag gaggatcgat cggttcagaa
    16801 atctgtcggc aaatcattca attcaatcct gcaaagctat tgcttttagg acatggggag
    16861 aactcgatct acttgattga ccgtgagtta cgcacgcatc atcaaaattg tcctacagaa
    16921 atcgtaccga tcatcgcaga tatccaagat cgcgagaaaa tcaatgagat catggaacaa
    16981 tatcatccag atatcgtcta ccatgcagct gctcataaac atgtaccact gatggaatat
    17041 aatccaaaag aagcagtcaa aaacaatatt ttcggtacaa aaaatgtagc agaagcagct
    17101 aaagcagcaa aagtgaaaaa cttcgtcatg gtatcgacag ataaagctaa caatcctcca
    17161 aatgtcatgg gttcaacaaa acgaatcgct gaaatgattg tgactggatt gaatgaagaa
    17221 ggctgtacga aattctcagc tgtcagattt gggaatgtcc ttggttctcg cggtagtgtg
    17281 attccagtat tcagagaaca aattgctcaa ggtggtccaa tcactgtaac agactttcgt
    17341 atgactcgat actttatgac gattcctgaa gctagtcgtt tagttattca atctggcgca
    17401 ttagcaaaag gtggcgaaat ttttattcta gatatgagtg aaccagtgaa gattgtagac
    17461 ctagcgaaaa acatgatccg attgagcggg tatagcgaag acgaaatcga aatcattgaa
    17521 acaggtatcc gtccagggga aaaactatat gaagaactat tgttggataa ggaaagaaat
    17581 gatgaagcag tttatgagaa aatctttgta ggaaacatca aaggctactc aatacaaaaa
    17641 gtgatggatt ttgttaagag cctgccgcaa gacgatgaac aattggctaa agacattgtc
    17701 acttttgcaa atgcttcgaa taagtagggg gagtaaagtg aaagcaatta ttataggagc
    17761 tggtggattt ggcaaagaga ttgcttttct attacaaagt gtctctagat atgaattgat
    17821 tggttttgtc gatgattcgt taaaaatgaa aaatcaagaa ttattgggaa aacctgtatt
    17881 aggaacaata gattcattaa tagaattaga agaagagact gctatttttc tgggaattgc
    17941 ttcgccagat atcaaggaga aaatatatca aaagataaat aaaaataata aactgatttt
    18001 ccctaattta gttgcaccaa gtgcactagt gggcataaat gttcagttag ggattggcaa
    18061 tattttgatg ccctatacga cttatactgc tgacgtagtt ttaggaaatt tcaatatgat
    18121 caatatcggc tctactatcg gacatgatgc tcaaatcggt aattataatt caatttttcc
    18181 aagtgtaaat atttcaggac atgttatatt aggagataaa aatgaaattg gagtaggtac
    18241 taaaataata caaaatctaa gaattggaaa tatgaatatt ataggtgcag gaagtgtagt
    18301 aataaaaaat attaataata atactaaaaa tgttggcgtg cctaccaaag taatagaaag
    18361 atgggattaa gttggaaaat aaacgaatat tattagcatc tcctcatatg agtgaggaag
    18421 gatatgaaca agagtatgta aaagaagcat ttgatacaaa ttgggttgct cctttaggtg
    18481 cgaacgtgaa tggttttgag aaagaattag caaaatacgt gggagctagt catgctgccg
    18541 cattgtcttc tggaacagca gctatacatt tagctttgaa agcggctggg gtcggtaaag
    18601 atgacatagt gatttgtcag tccttgacgt tctcagctac tgctaatcca attctctatc
    18661 aaggagctat acctgtattt gttgatagtg attacgaaac ttggaatatg aaacctgaac
    18721 atttgcgaac agcactagaa aaatatccca acacaaaggc tgtattagta gtacatttgt
    18781 acggtttatc agctaattta gacgaaatta ctaaaatatg caaagaatat gatgttactc
    18841 taattgaaga tgctgcagaa tcattaggaa caacgtataa aggaaaatat actggtacat
    18901 ttggcgacta tggaatttat tcttttaatg gaaataagat aatcacaact tcaggtggcg
    18961 gaatgcttgt atctaatgac aaagaaaagg tggaaaaagt gagattttgg gctacacaat
    19021 ctcgtgagaa ggcacgccat tatcaacaca atgaaattgg ctataattat cgaatgagca
    19081 atatcgttgc aggtatcggt cgaggacaat tgaaagtttt aaatgaaaga attgagaaaa
    19141 aacgatatat tcatagtttt tataaaaacg aattgtctaa attatcaaat atacaattca
    19201 tgccagaaaa taattggaat gaaccaaatt attggttaag tgtcataaca ataaagggaa
    19261 taaatacgaa tcatcttatt gatgagttag ataa
//
LOCUS       DACDLM010000057        17714 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.058, whole genome shotgun sequence.
ACCESSION   DACDLM010000057 DACDLM010000000
VERSION     DACDLM010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17714
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.058"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            3..815
                     /locus_tag="IV356_002035"
     CDS             3..815
                     /locus_tag="IV356_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HAP9015701.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            812..1612
                     /locus_tag="IV356_002036"
     CDS             812..1612
                     /locus_tag="IV356_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HAP9015702.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1773..3041
                     /gene="rseP"
                     /locus_tag="IV356_002037"
     CDS             1773..3041
                     /gene="rseP"
                     /locus_tag="IV356_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HAP9015703.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3109..4818
                     /locus_tag="IV356_002038"
     CDS             3109..4818
                     /locus_tag="IV356_002038"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HAP9015704.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            5030..9382
                     /locus_tag="IV356_002039"
     CDS             5030..9382
                     /locus_tag="IV356_002039"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HAP9015705.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            9526..9999
                     /gene="rimP"
                     /locus_tag="IV356_002040"
     CDS             9526..9999
                     /gene="rimP"
                     /locus_tag="IV356_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HAP9015706.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10023..11198
                     /gene="nusA"
                     /locus_tag="IV356_002041"
     CDS             10023..11198
                     /gene="nusA"
                     /locus_tag="IV356_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HAP9015707.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11220..11513
                     /locus_tag="IV356_002042"
     CDS             11220..11513
                     /locus_tag="IV356_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HAP9015708.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11510..11821
                     /locus_tag="IV356_002043"
     CDS             11510..11821
                     /locus_tag="IV356_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HAP9015709.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11834..14140
                     /gene="infB"
                     /locus_tag="IV356_002044"
     CDS             11834..14140
                     /gene="infB"
                     /locus_tag="IV356_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HAP9015710.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14167..14514
                     /gene="rbfA"
                     /locus_tag="IV356_002045"
     CDS             14167..14514
                     /gene="rbfA"
                     /locus_tag="IV356_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HAP9015711.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(14622..14843)
                     /locus_tag="IV356_002046"
     CDS             complement(14622..14843)
                     /locus_tag="IV356_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP9015712.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYYRKKKVEFFTFLFLFFG"
     gene            15291..17654
                     /locus_tag="IV356_002047"
     CDS             15291..17654
                     /locus_tag="IV356_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
                     /protein_id="HAP9015713.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWELFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKPGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRKDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFRSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAVTLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAEKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
BASE COUNT         6035 a         3146 c         3903 g         4630 t
ORIGIN      
        1 gaatgttacg tttttttccg caaaaaaaca aatatattca agaaaaaagc gaatttcaat
       61 ttaataccga tggaccaatt cctcagcaca ttgccatcat catggacggc aatggtcgtt
      121 gggcgcaaaa ccgtcgtttg ccacgagttg ctggccataa agaaggcatg gaaacagtaa
      181 agaaagtcac aaaaaaagca tcaaggcttg gagtgaaagt gttgacgctt tatgcctttt
      241 cgactgaaaa ctggaagcga ccaaaagatg aagtaagttt tctcatgcaa ctacctgtcg
      301 acttctttga tacgttcgta ccagaattga ttaaagaaaa tgtcaaagtt catgtcatgg
      361 gttatgaaaa cgtattgcca gaacatacgc aagatgctgt aagacgtgca attgagcaaa
      421 caaaaaacaa tactggaatg gtattgaatt ttgctttgaa ttatggaagt agagcagaga
      481 tcgtgactgc tgtccaagaa attgccgaag aagtagcaaa aggagaaata cacgcagaag
      541 aaatcgatga tgaattgatt gctaagcatt taatgacagg tttcttgcct aaagagttac
      601 aagatcctga gctgatgatc cgtacaagtg gagaagagcg aattagtaat tttctgttat
      661 ggcagatcgc atatagtgag ctgtatttta caaaagcgct ttggcctgat tttgatggtg
      721 cgcatcttga agaagcaatc gcctcttatc aaaatcgaga ccgtcgattc ggcggtgtaa
      781 aaaaaacaga agatgagaaa ggggatcagt catgaaacaa cgtgtgatca cagcagctgt
      841 ggcgctagtc ttgtttattc cgattatatg gatcggaggc atagcggttg agcttacagc
      901 agcaatctta gcggtagtag gagtttacga gctgttccgg atgaaaggat tgacactctt
      961 aagttttgaa ggagttttat ccgccgttgg tgcagtgtta cttgttttgc caaaagaaag
     1021 atggtttttc tttcttccag agaatgtaag tacatttatg ttattttatc ttatagttat
     1081 gattctttta ggaacatcag ttatttctaa aaatacgtat acgattgatg aagcaggttt
     1141 tcctgtgctt gtcagcttgt atgtgggaat aggtttccag aattttgtca atgcacgaac
     1201 agaaagcttg gctgttttga tatttggtct atttattgtt tgggcaactg atatcggagc
     1261 atatatggtt ggtcgacgtt atggtcagca taagttaagt cctgatattt cgcccaacaa
     1321 aacgattgaa ggtgcgctcg gtggtatcgg tagtgctgtt gtagtcgcat ttctttattt
     1381 attgctatac ccagcaaaag aactattcaa tcatggtatg tttgtcatgc ttctgatgac
     1441 gattattttt tcagcagtcg gacaatttgg tgatttggtc gaatctgcaa tcaaacgtca
     1501 ttatgatgtg aaagactcgg gaaatatctt accaggccat ggtggaatct tagaccgttt
     1561 cgacagtttg ctgtttgtat ttcctatcat gcatttattt ggcattattt agtaagtata
     1621 cctgcgtttc tttgtgaatt tcataaaaga cgcaggtttt tatttttcat tatattgata
     1681 ctattggtgt ctttggtata ctatggtaaa attatagtgt tttatcgttg ttttataaaa
     1741 aacacaaaaa acaagtaaag gagaaaaaag ctatgaaaac gattctgaca tttatcatcg
     1801 tttttggtat attagtgatt gttcatgagt ttggtcattt cttctttgcg aaacgatcag
     1861 gaatcctcgt ccgcgaattt gctatcggta tgggtccgaa aatttatggg catcaagcaa
     1921 aagacgggac aacatatacg cttcgcctat tacctattgg cggttatgtt cgaatggcag
     1981 gcaatgggga tgatgaaaca gaaatggcac caggaatgcc tctttctctt ttactaaatt
     2041 ctgacggcat cgtagagaag ataaatttaa gtaagaaaat ccaattgaca aatgctatcc
     2101 cgatggaatt gagccgttat gatttagaag atgagctgac tatcactggt tatgtgaatg
     2161 gagacgaaac agaagtagta acctaccctg ttgatcacga tgcgacgatt attgaaaacg
     2221 acggaacaga aatcagaatt gcgccaaaag acgtacagtt ccaatcggct aaattgtggc
     2281 agcgtatgct gaccaacttt gctggaccca tgaataactt tattttggca atcgtgttat
     2341 tcatcattct ggcatttatg caaggtggtg ttcaagtgac gaacactaat cgcgtaggag
     2401 agatcatgcc taatggagct gcggcagaag caggcttaaa agaaaatgat gaggtagtca
     2461 gtgtggacgg aaaagaaatc cattcatgga atgatctgac aacagtcatt acgaaaaatc
     2521 caggtaaaac attagacttt aagatcgaac gagaaggtca ggtgcaatct gtcgacgtga
     2581 caccgaaatc tgtagagtca aatggcgaaa aagttggcca acttggtata aaagccccaa
     2641 tgaatacagg ttttatggat aagatcattg gagggacgcg tcaagctttc agcggttcat
     2701 tggaaatttt caaagcctta ggatcactat ttacaggttt cagtttagat aaattaggcg
     2761 gacctgtcat gatgtaccaa ttgtcttcag aagcagcaaa tcaaggtgta acaactgtta
     2821 ttagtttgat ggcgcttctt tcaatgaatc tcggaatcgt caatctgctt ccgattcctg
     2881 ccttagatgg cgggaaatta gtcttgaata tttttgaagg gattcgcggg aaaccattaa
     2941 gtcaagaaaa agaaggaata ttgacattag ctggctttgg atttttaatg ttgttgatgg
     3001 tgctagttac atggaacgat attcaacgat tctttttcta gaaaaagttg acaaataggg
     3061 tataataaca aacgataact attttgagga aataaaggag tatatagaat gagacaatca
     3121 aaaatgttga ttccaacatt acgcgaagtt ccaaatgatg cagaagtatt aagccatcaa
     3181 atcttgctaa gagctggata tatccgccaa gtatcagcgg gtatttattc atatctgcca
     3241 ttagcaaatc gtgtattgga aaaactgaaa cgcattatgc gggaagaatt tgaaaaaatc
     3301 ggagcggtag aaatgctgat gcctgccatc ttgccagcag aactttggga agaatccggg
     3361 cgttacgaaa catatggacc aaacttgtat cgtttcaaag accgcaatga tcgaaaaatg
     3421 atccttggac caactcacga agaaactttt actgatttga tgcgtaatga aatcaattca
     3481 tataagaaat tacctttaaa tctttatcaa atccaaccta aatatcgtga cgaaaaacga
     3541 cctcgcttcg gtttgcttcg cggaagagag tttatcatga aagatgcata ttctttccat
     3601 gcaacggaag aaagtttgga cgagacatat aaagattacg aaaaagccta taccgaagta
     3661 ttcaagcgtt gtggcttaga atttcgctcg atcatcggag acggcggcgc aatgggcggg
     3721 aaagactcaa aggaattcat ggcgatctca gaaatcgggg aggatacgat ctgttattcg
     3781 actgaaagtg attatgctgc aaacttggag atggctacaa gctactatgt atcaaaaaaa
     3841 tcgcatgaaa cacagcttga attggagaaa gtagctacac ctaacgtaaa atcaattgac
     3901 gaagtagcag atttcttttc tgttgaacct caaaaaatca tcaagtctgt attgttcatt
     3961 gcggatgaac aacctgtcct tgttttggta cgtggagacc atgaagtcaa tgacgtaaaa
     4021 ctgaaaaact ttttatctgc tgacttttta gaagaagcaa cagaagaaga agcacaaaaa
     4081 tatctaggtg ctgagtttgg ttctgtcgga ccagtcggtg tttcagatga cgtaaaagta
     4141 tatgcagacc gttatgtcca agatttagcg aatgccatta ctggagcgaa cgaaacagga
     4201 ttccactata aaaatgtgaa tccagaacgc gatttcactg tgctttctta tgaagatctt
     4261 cgttttgtac aagaaggaga tccttcacca gacaacaacg gtgttcttgc ctttactcga
     4321 ggaatcgaaa tcggacatat attcaaaatc ggcactcgtt acagtgaatc tatgggagca
     4381 actgtactag acgaaaatgg acgagaaaaa tttgtgatta tgggctgtta tggtatcggt
     4441 gtaagtcgtt tattatcagc aatcgtagaa caacattcag atgaacaagg aatcaattgg
     4501 ccaaaaggaa ttgcgccatt tgatctgcat atcgtccaaa tgaatctaaa agacgaatac
     4561 caaacaagcc tgacgaatga actagaagaa gcgatgacaa aagctggcta tgaagtactg
     4621 gttgatgaca gaaatgaacg cgcaggagtg aaattcgcgg attctgattt gattggctgt
     4681 ccaatcagaa tcactgtcgg taaaaaagca gtggatggaa tcgtagaagt gaaaatcaag
     4741 aaaactggcg aaatggttga agtacgtaaa gaagaattgg cgaatacttt accaatcctc
     4801 ttgaaccaag gcgaataata agcgttaaaa cacagaaaat aaaaatagct gaatcagctg
     4861 tttttgacaa tctgatgatt cgcttttaaa attggaactg cgatttgaat cgcagttcca
     4921 attttttaat gtaaaactca gaaaaaacga gtatactaaa aggtactgaa aaagaagagg
     4981 ataagatgcg atcaattgca ttgtttctca tcagaaaggg cgtatatctt tgtcagaaaa
     5041 acgagattta tttgaaaaac tgttggaaca aatccaacta gaggaagcag aaaaaaatca
     5101 tccactgctt actgctggtg aaatggatag tgtagtggtc catcgtaaat cgcgtttatg
     5161 ggaatttacg ctacattttt ccaaaatttt gcctattatg ctatatcggt cattgactca
     5221 gcatctgact atcgctttta aagatattgc acaagtcaaa ctgaatatct tagcagatga
     5281 ccagacattc gatgaacagc tcttgcaaga ttactgggcc caagctttgg aaaatcagca
     5341 atgcgataca ccactagcac agcaagtatt gaaaacgcag gtacctgtga taaaagatcg
     5401 taaagtcatc ttgccaatcg acagtacagg agctatttct tatttgaagc aacaatactt
     5461 gccattagta gaagagttgt tcgtcagtta cggattccca aaatttcgta tcgaaccaga
     5521 agtggatgag cagcaagcgg aacgtgtatt gaaacttttt gaagaacgca aacaagaaca
     5581 ggcagaagcc tttatgaagc aagcagctga aagtctagtt gtccacgaac aaaagaaaaa
     5641 ggaaagaaaa gagcaatcgc cagctcttga aggacccatc cagctaggac gaaatattcc
     5701 agccgatgaa ccaacgacac caatgatcag tatcgttgaa gaagaacgaa gagtcacact
     5761 tgaggggtac gtattcgaca aagaagtcag agaactacgt tcaaaacgca agatcttgac
     5821 tttgaaaatc acagattata cttcatcatt tatcgtcaaa aaattctcga acggcgaaaa
     5881 agatgaacaa gtatttgatg cgatcagtgt cggtagctgg ttaaaggtac gaggaagtat
     5941 tcaagaagat acgtttgtcc gtgatttggt catgaatgcg caagatatca tagaagtcaa
     6001 acatacacct cgcaaagatt atgctcctga aggggaaaaa cgagtagagc ttcatgttca
     6061 tagcaatatg agtacgatgg atgcaacaaa cagcatctct gatcttgtgg cacaagcagg
     6121 aaaatgggga caccgagcta tcgccattac agaccatggt ggtgcgcaag cctttccgga
     6181 agcacatagt gctggaaaaa aagcaggtgt gaaaatctta tacggcgtgg aagcgaatgt
     6241 cgtagatgat ggtgtcccaa ttgcttataa tgatgcacat gaagcattga gtgaagccac
     6301 atacgtcgta tttgacgtgg aaacgacagg attgtctgca gtatatgaca cgatcatcga
     6361 gctagccgca gtcaaaatgt ataaaggaaa tgtgatcgaa agctttgatg aatttatcga
     6421 tccaggacat ccattgtcac gaacaacggt agatctgact ggtatcacgg atgaaatggt
     6481 tcgagggtca aagtcggaag aagaagtatt gcggatgttc cttgaatttt caaaagatac
     6541 aattttggta gcccacaacg cggcttttga tatggggttc ttgaatacta gctacgcaag
     6601 gtatggtatt cctgaagcgg ccaatccagt cattgatacg ttggaattag ctagatatct
     6661 gtatcctcaa ttcaaacgtt tcggattagg tgtgttatct aaaaagtttg gtgttagctt
     6721 ggaacagcat caccgagcaa tctatgatgc tgaagcaact ggtcacttag catggatctt
     6781 tgtgaaagag gcaatggaca atcataacat gctttatcat gatcagctaa atgagcatat
     6841 cggagaagga gattcttaca aaagggctcg acctttccat gtaacgattt tagcaaaaaa
     6901 tcaggcagga ctgaaagatt tgttcaaact gatttcaatg tcgaatgtcg aatacttcga
     6961 acgcgtccca cgaataccac gctcccaatt gaaaaagatg cgtgaaaatc tattgatcgg
     7021 ctcagcttgt gataagggag aaatattcga agccatgatg caaaaagggg tagaagaggc
     7081 aagaaaccga gcaaaattct atgattatat tgaagttatg ccaaaagcgg tctatgcgcc
     7141 tttgatcgag caagaattgg taaaaaatga acatgatttg gaagaaatta tccaaaattt
     7201 ggtagaaatc ggaaaaagtt tggataaaat cgttgttgca acaggtaatg tacattatct
     7261 gaacgaagaa gatgccattt accgaaaaat tttgatcaat tctatgggcg gagcgaatcc
     7321 gttgaatcgt catagtttgc cggatgtcca tttccgaaca accgatgaga tgctaactgc
     7381 atttcacttt ttaggggaag aaacagcgaa agagatcgta gtagaaaata cgaataaaat
     7441 cgcagatatc tgcgaagaag tgattccagt caaagatgaa ctttatacac cgaagattcc
     7501 aggttcagaa gatgaaatat cagaattgag ttacacaaaa gcaaaacaaa tgtacggaga
     7561 tccgttacct gagatcattc aaaaacgatt agaaaaagag ttgaattcta ttaatggtaa
     7621 tggcttctcg gttatttatc tgatcgccca aaaactagtg cataaaagta atgaagatgg
     7681 ctatctagta ggttcacgtg gctctgttgg ctctagcttt gttgcgacga tgacaggaat
     7741 cactgaagtt aatccattag cccctcatta ttattgtcca gagtgccaat attccgagtt
     7801 ttttgaagat ggtacgtatg gttctggatt tgacatgcca gaaaaacaat gtccaaaatg
     7861 tggtgcacgc ttaaacaaag acggtcatga tattccattt gagacatttt taggattcca
     7921 tggagacaaa gtgcccgata ttgatttgaa cttctcaggt gattatcaag cagaagccca
     7981 taactatacg aaagtattgt ttggcgaaga ctatgtttac cgtgccggaa cgattggtac
     8041 agtcgccgac aaaacagcat atggctatgt aaaaggatac gaaagggaca ataatctgca
     8101 gtttcgaagt gcagaagtcg acagattagc aaaaggcgct actggagtca aacggacaac
     8161 cggccagcat ccagggggga tcatcgttat tcccgattat atggatgtct atgattttac
     8221 gccgatccaa tatccagcag acgatcaaaa ttcagaatgg aaaacgactc attttgattt
     8281 ccactcgatt cacgataatg tattgaaatt agatattcta gggcatgatg acccaactgt
     8341 tattcggatg cttcaagatt tatcagggat cgacccacaa acgatcccta cggatgaccc
     8401 ggaagtgatg cggatatttg ccggtcctga agtacttgga gtaagtcagg aacaaattta
     8461 ttccaaaaca gggacattag gtattccaga attcggcact cgttttgttc gagggatgtt
     8521 agaagaaacg catcctacaa cttttgcaga actactgcaa atttccggac tatctcatgg
     8581 tacagacgta tggttaggaa atgcggaaga attgattcga cgaggagatg cgacactggc
     8641 ggaagtaatc ggctgtcgtg atgatattat ggtttatttg atccatgctg gattagatag
     8701 cgggatggca tttaaaatca tggaaactgt tcgtaaagga caatggaaca agatccctga
     8761 tgaattgcga gaaacctatc tatcggcgat gaaagaaaat aatgtgcccg actggtatat
     8821 cgattcttgt tcaaaaatca aatatatgtt tccgaaagcc catgctgcag cttacgtatt
     8881 gatggctctt cgtgtcgctt atttcaaggt ttatttccct attttgtatt actgtgcata
     8941 cttttctgta cgtgcagacg actttgatct agtctccatg tgcaaaggaa aagatgctgt
     9001 gaaacaagca atgaaagaaa tcacggacaa gggattagat gcttccgtaa aagaaaagaa
     9061 tcaactgaca gtgctggagt tagccaatga aatgctggaa cgaggattca aatttggaat
     9121 gattgatttg tataaatcgg atgccgttaa ctttgttatt gaaggtgata cgttgatcgc
     9181 accatttaga gctgtcccaa gtttgggaac caacgtggcg aaacaaatcg ttgaagcaag
     9241 aaaagacggt ccatttttat ccaaagaaga tcttgccacc cgcggtaaag tttcaaaaac
     9301 attgatcgaa tatatgaacg acaatggcgt attgaaagat ctaccagatg aaaatcaatt
     9361 atcgttattc gatatgctat aagcatctgt tttcctgtct gcttgtaatt ttaagcagag
     9421 tatggtatag ttcttatagg taatgatact aactgtgagt gagcggattt ttcgctcact
     9481 ctttttaatg gaattacgca cttaattttt aaggaggcga aacttttgag tagcgtcgtt
     9541 gaaacagtca cagaaatggt gacaccgatt ttagatgaac aaaattttga acttgtcgaa
     9601 gtcgaatttg taaaagaagg aaaaagctgg ttcttacgag tatttattga caaagaaggc
     9661 ggtatcgata tcgaagaatg cgcctttgtc agtgagaaac tgagtgaaaa acttgatgca
     9721 gcagatccag atccgattcc tcaagcttat ttcctggagg tatcctcccc gggagcagag
     9781 cggccattga aaaaagaaag cgactatgaa aaggcacttg gtgattatgt ccatgtctcc
     9841 ttataccaac cagtagatgg cgaaaaacaa tatgaaggat ttcttcaatc atttgatgct
     9901 gaacagctta cattgaaaat acgcataaaa acacgagaaa aagaattgac ttttgaccga
     9961 aaaaatattg caaaagctcg cttagctatc caattttaat cacggagagg aatcagaaaa
    10021 aaatgagtaa agaaatgtta aatgcgttag acgctttaga agctgaaaaa gggatctcaa
    10081 aagaaatcgt gatcgatgct ttagaagcag cattggtttc tgcatacaaa cgtcactatg
    10141 gccaagcaca aaacgtcgaa gtggaatttg atcagaaaaa aggaaagatc catgtctatg
    10201 cggtaaaaga agtaacggaa gaagtgatgg attcacagtt ggaagtctca ttgaaagatg
    10261 cacttttaat caatccagca tatgagatcg gtgatacgat ccgttttgaa gtaacaccaa
    10321 aagattttgg acggatcgct gcgcaaacgg ctaaacaagt tattttacag cgtgtacgtg
    10381 aagcagaaag aacgattatt tataacgaat tcagtgctta tgaaaaagac atcatgcaag
    10441 gaatcgtcga acgccaggat aaacgttata tttatgtcaa tcttggtaaa attgaggcag
    10501 ttctttctaa acaagatcaa atgccaaatg aattttatca accacatgat cgaatcaaag
    10561 tttatgtttc ccgagtagaa aatacgtcta aaggtccgca agtatttgtt agccgcagcc
    10621 atccagacct attgcgtcgc ttatttgaac aagaagtacc agaagtctat gatggaatcg
    10681 ttgaaattgt cagcatcgcc cgtgaagctg gcgatcgttc aaaagtggca gttcgctcaa
    10741 atgatccaaa tatcgatgca gtcggtacat gtgtcgggcc aaagggacaa cgagttcaag
    10801 caatcgtcaa tgaattaaaa ggcgaaaaca tggatatcgt cgaatggaat gaagatccag
    10861 ctgtattcat cgcaaatgca ttgaatcctg cacaagtcat ggatgtgatc ttcgatgaga
    10921 caaatccaaa ggcctgcaca gttgtcgttc cagactacca attatcgcta gcaatcggta
    10981 aacgcggaca aaatgcacgt ttagctgcta aattgactaa ccataaaatc gatatcaaat
    11041 cagaatctga catgacggaa ttttatgaaa atcaagaaca acaaaaagaa acagaagaac
    11101 tgcatgatga agcaatcgtt cagtcagatt taacagacga tgaatatgaa acaattgcat
    11161 tcaacaatga aacggtcgaa gaaaaaccag aagcttaact ttagtaagga ggcaaagaga
    11221 tgaaacaaag gaaaattcct ttacgcaaat ccgtggtttc aggtgaaatg aaacctaaaa
    11281 aagagatggt ccgaatcacc cgttcaaaag aaggggaagt atcgatcgat ccaactggaa
    11341 aaatgcctgg acgaggagcg tatgtctcac ttgagccgga agaagtacaa caagcttggg
    11401 ataaaaaaat tctcgatcga gtactcgaaa caacattaac agatgagttt tatcaagaac
    11461 ttcttgacta tgtcactcac caaaaagcac gtaaagagtt atttggaaaa tgaatacagt
    11521 taatcggcaa aaagccatga atctcatcgg tctagcgatg cgcgcgggaa aactaatcac
    11581 gggtgaagaa ctgaccattg ctgaaatccg caaacaaaaa gcaaaattgg tgtttgtggc
    11641 aaccgatgca agtgagaata caagaaaaaa gataaaagat aagagttcat attatgaagt
    11701 tccttgcttt gagctatttt ctgaagcaga aatcacgcag atgatcggaa aacctcgcaa
    11761 ggtattcgga ataatggatg ccggatttgc gaagaagacc aaggagctaa ttgaaggtta
    11821 ggaaggtgat tgcatgggca acaaaagaat ctatgaatta gcaaaagaac tcaaaaaatc
    11881 tagtaaagac gtcgtggaaa aagcacaaca acttggcatc gatgtgaaaa accatatggg
    11941 tgcgattact agcagtgatg agaagaaatt gcaacaagcg ttcaaaaacc caagcacgaa
    12001 acaacaagct gcacaacaag caagcagaaa accagccaat caacagccga acgatcaacg
    12061 taaaaaagaa acaacgaaca atcaacaaaa aaataaaaat aaccgcagtt atcaagatcg
    12121 cggtcaaggg agcggtcaag tgaatcaagg aaaaaaacca acaacaaacc aaaataatac
    12181 gggaaatacc agcagccaaa atcgtcaagg aacgagccaa ggcggcaatc aaaaccgtac
    12241 taacaataac aacaaaccaa acaataacaa tcgcggcaaa tttaataata ataaccgtaa
    12301 tcgttataat aaaaaaggta aaaaaggcaa acagcaacaa tcaactaaac cagctgtacc
    12361 accacgcaaa ttccgtgaat tgccagatgt attagagtat actgaaggta tgaacgtagc
    12421 agatattgcg aaaaaaattc atcgtgagcc agcagaaatc attaaaaaat tatttatgct
    12481 tggtgtcatg gtcaatcaaa accaagcact ggataaagat acgattgaac tgttagcgac
    12541 ggactatggc atggaaccac aagaaaaagt ccaagttgac attgctgata tcgataaatt
    12601 cttcgaggca gaagaagtcg atccagataa attagtctca cgtccgccag tagtaacgat
    12661 tatgggacac gtagaccacg ggaaaacaac cttattggat acattgcgcc attcacgtgt
    12721 aacaagcggc gaagccggcg gaatcacaca gcatatcggt gcctaccaga tcgatattga
    12781 tggtaaacca atcactttct tggatacacc aggacatgcg gcctttacaa gtatgcgtgc
    12841 acgtggagca agtatcacag atatcacgat cttagttgtt gctgcagatg atggcgtcat
    12901 gccacaaaca gttgaagcaa tcaaccatgc caaagctgca ggcgttccaa tcatcgtcgc
    12961 tgtaaataaa attgataaac caggtgcaaa tcctcagcat gttatgcaag aattaagtga
    13021 gtatgaatta attcctgaag catggggtgg agaaacgatt tttgttgaga tctcagcgaa
    13081 attcggccaa aacatcgaag aattgctgga aatgatcctg ttagtcgcag aagtagaaga
    13141 tttaaaagca gatccaacac aacgcgcaat cggaacagtg atcgaagcac gtcttgataa
    13201 aggtaaaggt cctgtgtcaa ccttacttgt ccaagaagga acacttcacg ttggtgaccc
    13261 aatcgttgtc ggtaatactt acggacgtgt ccgtgtaatg acaaacgatc ttggccgtcg
    13321 cgataaagaa gcaggacctg caacgccagt agaaatcact ggcttgaatg atgtacctca
    13381 agcaggtgac cgtttcgtag tcttcgaaga cgaaaagaca gcacgtgcag cgggtgaaga
    13441 acgcgcaaaa cgtgcattat tggaaaaccg tgctgccaca agccgtgtga ctttggacaa
    13501 cttatttgaa agcctgaaag aaggcgaatt gaaagaagtt aacgtaatca tcaaagcaga
    13561 tgtacaaggt tcagcagaag cactggctgc atcattgaag aagattgatg tggaaggtgt
    13621 ccgtgtaaaa atcgtccatt cagctgtcgg agcaatcaat gaaagtgatg taaccttagc
    13681 agcagccagc aacgctatta tcatcggttt caacgttcgt cctacaccgc aggcaaaagt
    13741 gcaagctgat actgaagaag tcgatattcg tcttcaccgt atcatctata aagccatcga
    13801 agaaatcgaa actgcgatga aagggatgct agaccctgaa tttgaagaaa aaatcaccgg
    13861 tcaaatgatc gttcgtgaaa ccttcaaagt ttctaaagtt ggtacgattg caggtgccta
    13921 tgtaacagaa ggatatattc gtagagatag cggtgtccgt gtaatccgtg acggaatcgt
    13981 aatctatgaa ggccaacttg caagtctgaa acgattcaaa gatgacgtga aagaagtcaa
    14041 aatgggttat gaatgtggtg cgatgattga aaaattcaat gacatcaaag tagatgacgt
    14101 aattgaagga tttatcatgg aagaagtcaa aaatgactaa aaactgataa aaggaggcca
    14161 atcattatgg ctaactaccg tgatcgccga gtcggtcaag aaatcttaaa agaagtcaat
    14221 gatattttgc gcaaaaaggt ccgtgaccct cgtgtggaga acgtaacgat cacagatgtg
    14281 aaagttacgg gggacttaca gcaagcaacg atctattaca gcattttatc tgacttagca
    14341 tcagataaga aaaaagcaca agatggattg aataaagcat caggattgat tcgtcgagag
    14401 ttagggcaca atctaagtat ttataagaca cctgaattgt tctttgaact tgatgaatca
    14461 gttgtctatg ggaaccatat cgatgaattg cttcgcgact tgaacaaaga ctaatcaaaa
    14521 aatcccgcaa atcctgtgaa atcaggggtt gcgggatttt tttgttttca ttaagacgta
    14581 ttacctaaga gttccatgac tttagtctgg tagcgtgtca gctaaccaaa aaagagaaaa
    14641 agaaaagtaa aaaattcgac tttctttttt ctatagtata taaatttttg catatagata
    14701 aagatcaaga taccgataac ggaagctaga ttgtaatcta ttttagtgac agtcaggtat
    14761 agccaagtaa ctagaagatc agtggaacct gcaccataaa agtttgagtt tgtcggtccg
    14821 ttgacagtta aaagaaaaat cacgttgaag ttattgatat ttccgattac gccgcttcga
    14881 tttggtcacg atccaaattt tggataatcc ctgtagaaat tagcatagta gctgggatac
    14941 caattcacat attgacaaag ataacagaga cttttacata aaacggatca atcaggaaag
    15001 gaattgctcg atccagcccc agttttccaa caatgtgtta actggcctag cgtcattcag
    15061 caaattatgc atgatgagga gcgaaatgaa ctgcggaaca gccattgtga taacgacaag
    15121 ttttttggat caatgtaaaa aacgtcagcg aaaggaaaaa tttcgtggtt ttttatacct
    15181 gttcatttgg ctagatataa aatccaaaca aatgaacaga agtgcttatt aggtttcaat
    15241 tgggagtatc tgcgctagaa taagagtaat aatgaaaagg agtgttatgt atggattatt
    15301 ctagtaaaga atactttgat aaaatgacgg cttggtggcg tgctgctaat tatctttctg
    15361 ttgggcaact ttatcttaaa gataacccct tactgagacg tacactgaaa ccagaagatg
    15421 tcaaaaaaca tccaatcggt cattggggaa cgattcctgg ccaaaatttt atttatgtcc
    15481 atttgaaccg agtcatcaat aaatatgatt tgaacatgtt ttatatcgaa gggccaggac
    15541 acggcggaca agtcatggta tcgaatgctt atttagatgg aagttacaca gagatctatc
    15601 cagaagtaac ggaagatgag acaggaatgc aaaaattatt caagcgattt tcatttcctg
    15661 gaggcattgc ttctcatgca gcaccagaaa caccaggttc tatccatgaa ggcggagagc
    15721 ttggatactc tctttcacat gcagtcggag ctgtattaga caatcctgaa gtaatctctg
    15781 ctgtcgtgat tggtgatggt gaagcagaaa ccggtccttt agctggaagc tggttctcaa
    15841 atgtctttat caatccagtg atagatggag ctgttttacc gatccttcat ttaaatggtg
    15901 caaaaatagc caacccaacg atcttggcac gtaaatcaga tggagaatta gcaaattact
    15961 ttaacggact tggctgggag cttttcttta ttgaaggaaa tgatccagaa aaattaaatc
    16021 ctgttatggc tgaaaaaatg gatcaagcaa tcgagaaaat caaatccatc caaaaagaag
    16081 ctcgcctgaa gacagcaaca gatgtcgtga tgccaaaatg gccagtattg atcgtacgca
    16141 caccaaaagg atggaccggt ccaaaagaat gggacgggga accaattgaa ggaaccttcc
    16201 gagcacacca agtaccgatt cctgtagatc aagaacatat ggatcatgca gatgctttac
    16261 tccgttggct gaaatcctat gaaccagaaa aattatttga tgcacaagga cgtattttag
    16321 aagaaatcag agaaattgcg cctactggtg accaaagaat ggcaaaaaat cctatcacca
    16381 atggtggaat cgatccaaga ccgcttatta tgccagattg gaaaaaatat actttgcaat
    16441 ttgaaaaacc aggctccgtt aaagcagaag atatgaccga acttggtaaa ttcgttcgcg
    16501 agatcattga gaaaaatcca gaaaatttcc gtatatttgg accagatgaa acaaaatcaa
    16561 accgattgaa tcaagttttc aaaacgacaa atcgccaatg gatggaaaaa atcgaaccag
    16621 aaaatgatga atggctttcg ccatctggtc gcgtcatcga cagtcaatta tcggaacacc
    16681 aagatgaagg gttcttagaa gggtacgttc tgactggacg gcatggtttt tttgcaagtt
    16741 acgaatcatt cttgcgagtg gttgactcta tgttgactca gcacttcaaa tggatacgga
    16801 aatcacatga cctttcttgg cgaaaagatt atccttcgct gaatctcatt gcaagctcaa
    16861 cagtcttcca gcaagatcac aatggatata gccaccaaga tccaggaata ttgacacatt
    16921 tggcagaaaa gaaggcggag ttcatccgtg aatatctgcc tgcggatgca aatacattgc
    16981 tcgcagtcat ggataaagca ttccgctcgt cagaaaaaat caatttgatc atctcttcca
    17041 aacatccgcg tgctcaattt tactcagcag aagaagcagc cgtcttagtg aatgaaggct
    17101 tgaaaatcat tgattgggct tcgacagcaa aagaggagga acctgaattg gtcattgctg
    17161 ctgcaggaac ggaatctaac ttagaagcat tagcagctgt aactttgctg ctggaagaat
    17221 tcccaaaact aaaaattcgg ttcatcaatg tcgtagattt attgaaatta cgtcatccaa
    17281 gtcaagatcc gcgtgggttg agcgatgaag aatttgatca atattttaca aaagacaaac
    17341 cgatcttatt tgctttccac ggttatgaaa cattggtccg cacgattttc tttgatcgtc
    17401 ataaccatca tttaatgatt catggctaca aagaaaatgg agatatcacg acaccatttg
    17461 acatgcgtgt agtaaatgaa cttgatcgtt atcatttggc aaaagacgca gctttaaaaa
    17521 tcaaaggaag tcaagcagaa gattttgcgg aaaaaatgga tcagaaatta caagaacatc
    17581 aaaactatat tcgtgaaaat ggtattgatc tgccagaagt attggattgg aaatggaaaa
    17641 atcttgacca ataaaatgat aaaatcgatc ccgcaaaaca gaatttttta cattgtatta
    17701 tttgtcaaat taag
//
LOCUS       DACDLM010000058        17610 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.059, whole genome shotgun sequence.
ACCESSION   DACDLM010000058 DACDLM010000000
VERSION     DACDLM010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17610
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.059"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..356)
                     /locus_tag="IV356_002048"
     CDS             complement(<1..356)
                     /locus_tag="IV356_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP9015714.1"
                     /translation="MKFGGHFLNKKQDQEYYIEKLEKENLELKERIRYYESKFHKRSD
                     CMKPNLIETGKRIKSIRSNLGMTMEQFAILTDSSNTSAVNNWERGYNLPNKTKLKKIA
                     ILGNTTTDWIKWGTLE"
     repeat_region   864..1169
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=1002..1037
                     /rpt_unit_seq="atttgagaaccatgtcgtcttatatagctccaaaac"
     gene            complement(1277..2449)
                     /locus_tag="IV356_002049"
     CDS             complement(1277..2449)
                     /locus_tag="IV356_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015715.1"
                     /translation="MTKKIEVYVDGSQEERDSFFGFFWKNSREYVKALNMVYRQLMFE
                     ELIKDAIKEMDQGYVEREKSIQNRIEKLAYTDPIDQKKLDKAKAELSKLRNEKNKEAR
                     EILTQAIGLKSQTRTRDVAKKLDFDFGDFVDSANMKASKDFGNDFVGIVTGQRTPRVY
                     RNKSKYGLLPFRGRDIKIHKADKFYISLPKGFRFKVNLGSKPRKARDSALTLEYIMDG
                     KYKLNQSNLIFEGNKLFFNLTISFEKDYHKLEFKEGSELTIKFTDLCSGECLVNNKSV
                     IDFGDSKYISNFKNKIKAMKSREQSRGVFSKGGHGRKRKLDQDRWEAIKKRESNFVKT
                     YNNQCSAKIVQTAIRNKAQIICISEPDKSYGEWAYYQLKEQIINKGKRYGIEVKSM"
     gene            complement(2694..3662)
                     /locus_tag="IV356_002050"
     CDS             complement(2694..3662)
                     /locus_tag="IV356_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAP9015716.1"
                     /translation="MSLGNEKPYYVVIGGVNGAGKSTIYQVQNLKRKELDTDRINADE
                     ILRSFGGNWKKQADINKSMREVLREIEGHFKEGKSFHHETTFGGNPYPDKKRLLNAKK
                     LGYESFLIYIGLDSPERAIERVKSRVAKGGHGVPEDVIRKRYEFSLRNLAELEKYFDN
                     VSIYDNSDEFSYIYVKENHTVVANNTQEYNWVPKAIQEKSAEIPISKQIIKDISQEGR
                     SPKETLERIYSASDDFISDRFLKAEQVDDFYMNHKNEIKERILAISFSTGVSEDELVG
                     QDKKRNSCKLSYINSVGELLEKTDSELSGMEASRDRSIKKTDFEIE"
     gene            complement(3659..3856)
                     /locus_tag="IV356_002051"
     CDS             complement(3659..3856)
                     /locus_tag="IV356_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015717.1"
                     /translation="MRDMTEAVKELKKMYPDVLNMTVDDFHEALKNAESEEERTFYLT
                     LSSFVTRVDQKKVINQKDFKI"
     gene            complement(3867..4184)
                     /locus_tag="IV356_002052"
     CDS             complement(3867..4184)
                     /locus_tag="IV356_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015718.1"
                     /translation="MKDYASRKFIHLEPMKELVINGNEYNDYKSLFVKEQPKGGIRMK
                     NLPDFRLIEVNNLGIIEDYLAKLDEAVKQSIEKNGEDHVLTVVLKDLKDRLEAEAENF
                     NKD"
     gene            complement(4221..4439)
                     /locus_tag="IV356_002053"
     CDS             complement(4221..4439)
                     /locus_tag="IV356_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015719.1"
                     /translation="MVNKKETFKVGMEVQGVVIGSGELIEGEVISLLANVAVVKAIGK
                     APVVMKKCSMMCLDGLNNPITQRFENVI"
     gene            complement(4548..4739)
                     /locus_tag="IV356_002054"
     CDS             complement(4548..4739)
                     /locus_tag="IV356_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015720.1"
                     /translation="MEQTRMFWSDRMQDHLDCIYKTREQLNKLDTVRYYFTYFSENDE
                     QRWDIFHDGNYEEFFYTES"
     gene            complement(4900..5256)
                     /locus_tag="IV356_002055"
     CDS             complement(4900..5256)
                     /locus_tag="IV356_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015721.1"
                     /translation="MNDTIAILSDSLIDLDKTSTDYMIIEEQLKNKNPEFDIQEKSLR
                     IELPKFKQKKLITILFEIIERYGLTYYQIWTDKKDGQYTKGVSIEAVREDDQVSIKAV
                     QPLMGYNEELLSCLNV"
     gene            complement(5281..6285)
                     /locus_tag="IV356_002056"
     CDS             complement(5281..6285)
                     /locus_tag="IV356_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3991 domain-containing protein"
                     /protein_id="HAP9015722.1"
                     /translation="MDLKKAKKVSIVDFCKQNGIGLKQDSREYYRLEDHDSCVISDRK
                     NLFKWNSKDLGGDIFDFIKAYYDCSFKEAKQKLEDSDYEVHSFNTKVKKSPYQYQKEN
                     EVPVSVAKSYLVNERRIDTALVEDFLSKGLIKQDKKGNVLFLWKKDQEIVGCTEQGTR
                     KFFHEGKQKDVTWKKIQENSKEYSGFNVTFGQPDKMYFFESEIDLMSYITQKPEKAEN
                     ATFVSMNGLKVGNVLHGVTEHYNKFKSLPSETVLCVDNDKAGRTFIETEFKEKGIGRE
                     GIGISEVKVDVPLREGFDWNDNLTRGKEAFKRFKLEDVSKIVNFTHKLSLNTPVYEME
                     "
     gene            complement(6322..6582)
                     /locus_tag="IV356_002057"
     CDS             complement(6322..6582)
                     /locus_tag="IV356_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015723.1"
                     /translation="MIGQENRNFLETQGEYRQINNSHFVICEDVQIAFKMALKYGKSI
                     RKKIIREKKSKKIGFWELSLRDGLNFIFCTEDYYEKYKCTLS"
     gene            complement(6591..7664)
                     /locus_tag="IV356_002058"
     CDS             complement(6591..7664)
                     /locus_tag="IV356_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015724.1"
                     /translation="MSNEQNYETGGTYRLFHGSMNKFDEFSLDHKGLNGTANGFGVYL
                     TPNKEMATMYAEQGSNGNNGFVYEVNVELEKPISMNERTITDEELSKVIDKLQESNDI
                     LNDYNDVSYYGEKVVKREVIASLSENENDVDLINDIGNTIGDHEATAKAFYDVGKYTH
                     IIAEEQLRQKDVVIVVLQPDKVKIETIHDLIEERNSLESSEDMTDKFVGHKVSEVPIR
                     EVVIKDFEQELETTNYYDKQAWQERIEYLENMEEPVSRLALDSDINEFYDSHKEEIET
                     KLTNLSEKLEIDKEELLGFPVDTSSTEYKKATSIMAYNGAMREIYDEIENDTFEIPPV
                     SEEMENKILKLTNFENTTKFEME"
     gene            complement(7673..9499)
                     /locus_tag="IV356_002059"
     CDS             complement(7673..9499)
                     /locus_tag="IV356_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAP9015725.1"
                     /translation="MAYKKGNWKPKTKEQKQKELDDLIKVSNSKIEQYQSNPEDMIEF
                     AKFMSKIHNYSPLNLSLIDEGFEGAIAVASYDGWKKLGFQVKAKEKGIGIYAHAPVTV
                     FIDENGEEKTLKEATSEQKEKIKNGELRSKKIKHFKKGYVFDISQTNATEADLPKIFP
                     NRVWNFNIDGELSVSQLEKGVNHLAESMNISIKDMNESGRGEMGSARGEYIQYVDGRE
                     EIVLNSRNSRTQNLTTSIHELAHKKLHNKNEHGSSYSIPIKEFQAEMTSFIVCHNYGI
                     DTSDFTIPYIANWTKNNEKIDPKNFRQIMQEVRETSIDFISTIDKKVLEEQQTAFNAL
                     KNSFVPNENKEQIQQKSDLEFHNFYDSTINDPDRTIHGSYLEAMVDYYRGKYGENSIK
                     LTHSNYDVTAKIGENYVTYYSDTKQFDVCDVYGVVFENPSENKHDRLLLDRSPENCDY
                     VEKFVVESLKACENHELKNDTLKLSEPLRSVVINEAVYNLSENANNYYNEKCWQEEIE
                     NQTNINDVKELNSCMTAEDFYESHKQEIENTITDFESVSGTNLRDTIDNESYKEVASV
                     VAYKLVATKVKYEMDEGTFKIPENSNLEKPTVKTAERSFEME"
     gene            complement(9654..10520)
                     /locus_tag="IV356_002060"
     CDS             complement(9654..10520)
                     /locus_tag="IV356_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015726.1"
                     /translation="MKKLRVIATIPMFFSFALLLSACGKEEAGAKSNEAHNISFIDSA
                     EQKDSRCWLVVETSSKNKTPIDKNEYVKAVIQTKNGKAKVFKTDMEQLTLEKVSKMSD
                     EEIIEQALNADKQKFNDKKKSDIDSYNATLDSVKTELENEEKQEFQNDQKIADFQDSI
                     PKIQADIEEIDGVQYSEPEWEKVSATIKMDNENKSPSMETVKLSYKYLDSPIWNLNSF
                     GEVSSEGELSYEPTSMDLKLSIPVATTKVLDNFYSGYSNDELDQLLLTKVASKDNKVQ
                     LDSKGKNVSIVE"
     gene            complement(10907..11170)
                     /locus_tag="IV356_002061"
     CDS             complement(10907..11170)
                     /locus_tag="IV356_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015727.1"
                     /translation="MIDFRTVMDKLSNGDFRVLIELYLNVTSTVKEFLYSNPKIALVL
                     VAVLIVFAVISFIKKMIPLLIIGAVLILGLYFPEVLDQIKNIF"
     gene            complement(11172..11501)
                     /locus_tag="IV356_002062"
     CDS             complement(11172..11501)
                     /locus_tag="IV356_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015728.1"
                     /translation="MKNFDIVCSNTKNIYLRELLNSDSETIEDVKKIIVLFEKENMEL
                     ENWGLFEIPISGNYCFYNWKTEDDVAFANYFFDKNYFSPLYIDKHSNEQVASSIKEAI
                     KLERVRK"
     gene            complement(11523..13043)
                     /locus_tag="IV356_002063"
     CDS             complement(11523..13043)
                     /locus_tag="IV356_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015729.1"
                     /translation="MTEHIFNRKSASIILKAKFETGKNKKKNHMVELQKFVDYISRQE
                     AIRQDKLDHDYSEDELNELARIEKALEKIEQETDQPVIKDLREMDKYIDYMTRKKAIL
                     ENVDNEIVNGAFSNTKRYITKKDISKIKESVIEAKNNGSVMFQDVISFDNDFLVREGY
                     YNPETNELNENILYEATKSMMGKMQEKEELVDPFWFATIHRNTEHIHIHVTAMERKNT
                     REIMEYDGVLQARGKRKQSTLDDMIFKFGSKILDRTNEFEKISKLRKEVPLELKQSVK
                     DSLIQLYVENNSRYDKELVKYLKELKKEIPSTTRGYNELPEETKEKIDEVTNYMTKDN
                     PKRKEYDRMTKEIDELYQTTYGKRYNPQEYYLNRKKDFNARMGNAVVGQIKLLKQSEE
                     KNLKSNELKNLLDGKKLNVKFDREKPEFKTKYAKQSYDDFQKRLEERQLAREKNEVHF
                     KKISEKFKDKKLIRKIDRVINDDLNMYRAKNDYEVAQRMIEQEKMRQAREFEIGMN"
     gene            complement(13126..13593)
                     /locus_tag="IV356_002064"
     CDS             complement(13126..13593)
                     /locus_tag="IV356_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015730.1"
                     /translation="MNYPYFKVSATEDVKEKFNKCFEVNKSVFQTKANMFRYVVSNLP
                     MLTKANQNFRDPEKEELAKNLEEAKLKISELETIIELQKQQLENFNKKEDSTHKDYSE
                     QLNSIEESVYKLLINSGLASKELEEERAEPEKESSRLGDGTMFSSPSLRFTTD"
     gene            complement(13590..13886)
                     /locus_tag="IV356_002065"
     CDS             complement(13590..13886)
                     /locus_tag="IV356_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015731.1"
                     /translation="MDVSIRGIDPQYVKEIDKKVKKIQERTGKKFSRNDYFLAIIRQD
                     SEIDLIDYKKSEFDLVVEKLLLSNEQMVESISELTSVYERLFNFLISERSDLNK"
     gene            complement(14237..14467)
                     /locus_tag="IV356_002066"
     CDS             complement(14237..14467)
                     /locus_tag="IV356_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015732.1"
                     /translation="MCNSIVTIQEKAEEELMRIEAEYKEKRKAIKRKKNAELKKYKEE
                     QALKLGMMLCKYYDCYDINEVLKKANLNQFCE"
     gene            complement(14503..15399)
                     /locus_tag="IV356_002067"
     CDS             complement(14503..15399)
                     /locus_tag="IV356_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015733.1"
                     /translation="MNKKYSIHNKKEPNKKNKAQIDKVYKKTKGVKLYLGAILGFLAI
                     GMIIVFSPYVMGKSYDFETVKMSSAQNVTSSLNMYVDDMEINREAGLFKLVLRYQDDT
                     GTKSLSNIKSDYKLNFITNKNNEDVKTKVVKLSDEYTVIYYQNLPKDFGVISVTVNPR
                     YIYPELEPSNDLKEKEIKFYAVDKDIKSNAKLEVESTSDLQKDNFKYQIKAIENSIKD
                     EKKSIEKMNLANKVVQKDIDKANQNLEFQTLDEQTDTKNEISSMQTTIENNKSSIEES
                     ENKIKQFEEKIKQLEKSASRFE"
     gene            complement(15413..16063)
                     /locus_tag="IV356_002068"
     CDS             complement(15413..16063)
                     /locus_tag="IV356_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HAP9015734.1"
                     /translation="MIKRKNDNKWKYICGVLLIILVLGGLLSQLHTSNIQAKNKKLDQ
                     EVTQLEEQNSKLSKNISDLNANVEANLTNDDGSELNKQIAEVAKKFVELYPVYDIEKV
                     EEKKADLEKIATPSVADSIVPDDMITTSKKTLESKSTTQKGEAYSSDPTFKSKYKDSK
                     LYTNYVNANTINYFAEVNYKTESSSGDTENTVYMLFEVTNKDGQVLVDNYEIKYLK"
     gene            complement(16077..17213)
                     /locus_tag="IV356_002069"
     CDS             complement(16077..17213)
                     /locus_tag="IV356_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015735.1"
                     /translation="MEQNKNNNVASTLARQGMKQVSKKIGLALKIKIGVVIGLITLVG
                     LLVIGSLATLQGTQTATNTGGAEVIGGNKPLSPEVQKWQKTVEKYAEKYGIKELVPYA
                     LAIMQCESGGKLPDLMQSSESAGLPVNTLQYEESIDQGLKHLSNVYNIAKSYGMESNY
                     DGIVQAYNYGIAYMHYLGKNKKTHTIETAEAYSKNVVAPSLGNTTGQTYSYVNEVSIK
                     YGKTYLYLNGGNFYYAELVKQYIGGGSGNPANPSEFWGKMKTEMEKYQGWPYVWGGKN
                     PTTGFDCSGLTAYLYQFSAGITIDSYTVTQYEATEAVSIKEAKAGDLIFFRGTYGAPD
                     FISHVGIYVNETTMYDSNSSGIGYHNWQDSYWQSHSPEIRRVKK"
     gene            complement(17235..>17610)
                     /locus_tag="IV356_002070"
     CDS             complement(17235..>17610)
                     /locus_tag="IV356_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tra protein"
                     /protein_id="HAP9015736.1"
                     /translation="INSNNKYACEYVLSFEREMRKMRAGVYFATQTPEEIIPKDSGSE
                     VADVIRNIFNLCTFKCFFNLDSALLEDIKKVLGNTITDTEIMLLPELEVGQAVVQTSS
                     EDTYMINFDPYPEQIERFDGGQ"
BASE COUNT         5095 a         3378 c         2037 g         7100 t
ORIGIN      
        1 tcttctaaag ttccccattt aatccagtca gtagttgtat ttcctagtat agctattttt
       61 tttagtttgg ttttattggg taagttgtaa ccacgttccc aattattaac agcactcgta
      121 ttagaagaat cagttaaaat agcgaattgc tccattgtca ttcccaaatt agaacgaatt
      181 gatttaattc ttttacctgt ttcaataaga tttggtttca tacaatcact tctcttatgg
      241 aatttggatt catagtatct tattcgctct ttgagttcta agttctcttt ctccaatttt
      301 tctatataat attcttgatc ctgtttcttg ttcaaaaaat gacctccaaa tttcacattg
      361 tgttacaccc taatgttaca cctccaaacc ttattatact gtactttacc atatgataca
      421 atagggtata cccttatgta acacgcaaaa caaaaaaata gtcttagcat gtaactaaga
      481 cctaaaagat atactgactc attgatattt aaaatctgtt tatttacaca ttttcaagtg
      541 tatccgtgtt tatttgagaa ctacattgtt ttacatggtt ctaaaaccaa caaaaccatt
      601 taagagtatg cgtgataatt tgagaactat gttgttttac atggttctaa aacattttga
      661 tagtcaatta aaaatataca tttatttgag aactatgttg ttttacatgg ttctaaaacc
      721 tcaacaatat tcgtccttcc gtctggtcac acaatatgac ggagttgacc cttcagtgag
      781 tggaatttcc ctcactattt cgttgccaaa tcaacgattt ctctacttat ctataactat
      841 ttccaaaata ttactatatc tatttttgag tactatgcta ttttatatga ttccaaagcc
      901 ttgtcaactt tttggatata ctcttctttc gtatcatttg agaaccatgt cgttttatat
      961 agctccaaaa cagagactac agatcaattc aataaagcat tatttgagaa ccatgtcgtc
     1021 ttatatagct ccaaaacttt ctacaaagct aaacaaatct aaaacctatt tgagaaccat
     1081 gtcgtcttat atagctccaa aacgcaaaga tataatcgtc tttttgtttg ataatttgag
     1141 aaccatgtcg tcttatatag ctccaaaacc tcaacaacat tcgtccttcc gtctggtcac
     1201 acaatatgac ggagttgacc cttcagtgag tgagtgtccc ctcactattt cgttgccaaa
     1261 tcaacgattt tttattttac atacttttaa cttctattcc gtatcttttt cctttattta
     1321 ttatttgttc tttcaactga taataagccc attccccata acttttatct ggttcagaaa
     1381 tacaaattat ttgtgcctta ttgcgaatag ctgtttgaac aatttttgct gaacattgat
     1441 tattataagt cttaacaaaa ttactttctc ttttctttat ggcttcccat ctatcttgat
     1501 ctaattttct ttttcgacca tgaccgcctt tagaaaaaac tcctcggctc tgctctcttg
     1561 atttcattgc tttaatttta tttttgaagt tacttatata tttgctgtca ccaaaatcaa
     1621 tcacagattt attattaact aaacattcac cgctacacaa atcggtaaac tttatggtta
     1681 actcagaacc ttctttaaat tctagcttat gataatcttt ttcaaaagaa attgttagat
     1741 taaaaaacaa tttattccct tcaaaaatta ggttgctttg atttaacttg tatttaccgt
     1801 ccataatata ttccaaagtt aaagcgctat ctctcgcttt tctcggtttg ctacctaaat
     1861 ttactttaaa cctaaatcct ttaggtaaag agatataaaa cttgtcagct ttatgaatct
     1921 taatatcccg acctctgaac ggtaacaatc catatttact tttatttcta tagactctag
     1981 gtgttctttg accagtaaca attccaacaa agtcattgcc aaaatcctta ctagctttca
     2041 tatttgctga atcaacaaaa tctccaaaat caaagtctaa tttttttgct acatctcgtg
     2101 ttctcgtttg actcttcaat cctattgctt gcgttaatat ttctctcgct tctttatttt
     2161 tttcatttct caatttagat aattcagctt ttgctttatc aagttttttt tgatctattg
     2221 gatcagtata cgctaacttt tcaatcctat tttgaatact tttttctctc tcaacatagc
     2281 cttgatccat ttctttgatt gcatctttta tcagctcttc aaacatcaac tgtctatata
     2341 ccatattcag cgcttttaca tattctctac tatttttcca aaaaaaacca aaaaaagaat
     2401 ctctttcctc ttgtgatcca tcaacatata cttctatttt tttagtcata gttattattg
     2461 tcaattttag cacctcatta ttatgtatct ggtatataat aataataaca tatttattag
     2521 accataatca acaatcaatt gtctacttgt agtaattatt ttaaaaacaa gaactaaaaa
     2581 tgatatatta tcccttatgt ctacatgtag tcatttcgtt taaaaaaata agaagtgctt
     2641 tcgcactcct tattaaattt atttactatt aaccgtttca gctacatctt cttttattca
     2701 atttcaaaat cagttttttt tatacttcta tctctgcttg cttccatgcc cgatagctca
     2761 ctatcagttt tttctaaaag ctcacctaca ctattaatat atgacaactt acaagaattt
     2821 ctttttttat cttggcctac taattcatct tcagatactc ctgtagaaaa actaattgct
     2881 agaatccgtt ccttgatttc atttttatgg ttcatataaa aatcatcaac ttgctctgct
     2941 tttaaaaaac gatcactaat aaaatcatca cttgctgaat atattctttc aagggtttct
     3001 tttggactcc gtccttcttg ggatatatcc ttgataattt gtttgcttat aggaatttca
     3061 gcgctttttt cttgaatagc tttgggaacc caattatatt cttgcgtatt attggctaca
     3121 actgtatgat tctctttaac ataaatataa gaaaactcat ctgaattatc atagatactt
     3181 acattatcaa aatatttttc taactctgct aagtttctta aagaaaattc gtatcgtttc
     3241 cttattacat cttcgggcac accgtgacca cctttagcaa cacggctttt aaccctttca
     3301 atcgctcttt ctggtgaatc tagtcctata tagattaaaa acgattcata acctaatttt
     3361 ttagcattta gaagtctctt tttatcggga taaggattac caccaaaagt cgtttcatgg
     3421 tgaaaagatt ttccttcttt aaaatgacct tcgatctctc ttaaaacttc acgcatactt
     3481 ttgtttatgt ctgcttgttt tttccaattt ccgccaaaac ttctcaaaat ttcatctgca
     3541 ttaattctat cagtatcaag ttcttttctt tttaaatttt gaacttgata aatagtagac
     3601 ttaccggcgc cgttaacgcc cccaataact acataatacg gtttttcgtt tcctaaactc
     3661 atattttaaa gtctttctga ttaattactt ttttttgatc tactcgtgtc acaaaactag
     3721 aaagtgtaag gtagaaagtc ctttcttcct cactttctgc attttttaag gcttcgtgaa
     3781 aatcatctac agtcatattc aaaacatcag gatacatttt ctttaattct tttacagcct
     3841 cggtcatatc tctcattccc ttcttattag tctttattaa agttctctgc ttcagcttct
     3901 agtctatctt tcaagtcttt taaaacaacc gtaagtacat ggtcttcacc atttttttca
     3961 attgattgtt ttaccgcttc atctaactta gctaaatagt cttctataat tcctaaattg
     4021 tttacttcaa taagtcggaa gtccggtaaa tttttcatcc gaataccacc tttaggctgt
     4081 tcctttacaa ataaagattt gtaatcatta tattcattcc cattaataac caattctttc
     4141 ataggctcta agtggataaa tttacgtgaa gcatagtctt tcataataat ctctcccagt
     4201 agaaaatctt cttttttcta ttatatcacg ttctcaaagc gttgagttat tggattgttt
     4261 aaaccatcaa gacacatcat gctgcatttt ttcatcacta ccggtgcttt tccgattgct
     4321 ttaactaccg ctacattagc taacaaacta attacttctc cctcgataag ctctccgctc
     4381 ccaataacaa cgccctgtac ttccatacct actttaaacg tttctttttt atttaccatt
     4441 attccgctct ctttccatga ctacttgtag tcatttgaat attttttagg ggaacggttt
     4501 tccgttccct ttcatcaaat agaattcttc atcatttcaa caaataatta actttcagtg
     4561 taaaaaaatt cttcgtaatt accatcatga aaaatatccc atctttgttc gtcattctca
     4621 ctgaagtagg taaaataata tctgacagta tctaacttat ttaattgctc tctggttttg
     4681 taaatacaat ccaagtgatc ttgcattcga tctgaccaaa acattcttgt ctgctccatc
     4741 tattatctct cctttttatt aaatcaaggg tttgagcctt tgactacttg tagtctatag
     4801 ctatatcata caggaatgac tacttgtagt caatagtttt ctttagttta attaactgtc
     4861 tattcgtagc caaataatgt aaaaaacgcc tagtttacac tagacgttta aacaactcaa
     4921 taattcttcg ttatacccca ttaagggttg aactgcttta atacttactt gatcgtcttc
     4981 tctaacggct tctatgctta ccccttttgt atattggcca tctttcttat ccgtccaaat
     5041 ttgataataa gtaagcccat atcgttcaat aatctcaaag agaatagtta ttaatttttt
     5101 ttgtttaaat tttggtaatt caatacgcaa tgatttttct tgaatatcga actctggatt
     5161 tttattttta agttgttctt caataatcat atagtctgta gacgtcttat ctaaatcaat
     5221 taatgaatct gataagattg ctattgtatc gttcataaca catcaactac tttcttcttg
     5281 ttattccatt tcatatacag gagtattaag agataattta tgtgtgaagt tcacgatttt
     5341 tgatacatct tctaacttga agcgcttaaa agcttctttt cctcttgtta aattatcatt
     5401 ccaatcaaat ccctctcgca aaggtacatc gacttttact tcactgattc ctatcccttc
     5461 tcttccaatt cctttttctt taaattcagt ttcaataaaa gtacgtccgg ctttatcatt
     5521 atcaacacaa aggactgttt ctgaaggcaa tgatttaaac ttattataat gctctgtaac
     5581 cccatgcaat acattaccta cctttaatcc attcatgcta acaaacgtag cattttcggc
     5641 tttttctggc ttttgtgtaa tgtacgacat caaatctatt tcactttcaa aaaaatacat
     5701 tttatctggt tgaccaaaag ttacgttaaa tcctgaatac tctttagagt tttcttgtat
     5761 ttttttccat gtaacatcct tttgtttgcc ttcatgaaaa aattttctag ttccttgttc
     5821 cgtacaccca acgatttctt gatctttttt ccataagaac aaaacatttc cttttttatc
     5881 ttgtttaatt agtcctttag ataaaaaatc ttccactaaa gctgtatcga ttcttctctc
     5941 atttactaaa taagactttg caacagatac tggcacctca ttttctttct gatattggta
     6001 cggagatttt ttcacttttg tattaaacga atgaacttca taatcactat cttcaagttt
     6061 ctgttttgct tctttaaatg aacaatcata gtaggctttg ataaaatcaa aaatatctcc
     6121 ccctaaatcc tttgagttcc atttaaaaag atttttgcga tcactgatta cacaagaatc
     6181 atgatcttct aatctatagt attctcttga atcttgcttt aaacctatcc cattttgttt
     6241 gcaaaaatca acgatactta ctttttttgc ctttttcaaa tccaaacaaa aacccccttt
     6301 actagaccat cactagtaaa attacgataa ggtacacttg tatttttcat aataatcttc
     6361 tgtacagaaa ataaagttta gcccatccct aagagataac tcccaaaacc ctatcttctt
     6421 gctctttttt tctctaatta tcttttttct aatacttttt ccgtacttca aagccatttt
     6481 aaaagcgatt tgtacatctt cacaaattac aaaatgacta ttattaattt gacgatattc
     6541 accttgcgtt tctaaaaaat ttctattttc ttgtcctatc attcatttat ctactccatt
     6601 tcaaattttg ttgtattttc aaaattagtc aatttcaaaa tcttattctc catttcttca
     6661 gaaacaggtg gtatttcaaa cgtatcattt tcaatttcat cataaatttc tctcattgca
     6721 ccgttgtaag ccatgataga cgtagctttt ttgtattccg tagaagaagt atctactgga
     6781 aaacctagca gttcttcttt atcgatctct aacttttcgg ataaatttgt caatttcgtt
     6841 tcaatttctt ctttatgact atcataaaat tcattaatat cactatctaa tgctaatctg
     6901 gaaactggtt cttccatgtt ttctaagtat tcaatgcgct cttgccaagc ttgtttgtca
     6961 taataattag ttgtttctag ctcttgctca aaatctttta tcacaacttc tcgaatagga
     7021 acttccgaaa ccttatgccc aacaaattta tctgtcatgt cctcactact ttctaagcta
     7081 ttccgttcct cgattaaatc gtgaatagtt tcaatcttta ctttatcagg ctgtaacact
     7141 acgataacta catccttttg tcttaactgt tcttccgcaa taatatgtgt atatttccca
     7201 acgtcataaa atgccttagc agtagcttca tgatctccaa ttgtatttcc aatgtcgtta
     7261 atcaaatcta cgtcattttc attctcacta agagaagcaa tcacttctct ttttacaact
     7321 ttttctccgt aataactaac atcattgtaa tcatttaaaa tatcattact ttcttgtaat
     7381 ttatctatta ctttagaaag ctcttcatca gtaatagtgc gttcattcat agaaatcggc
     7441 ttctctaatt caacatttac ttcatatacg aaaccattat ttccgttact accttgttca
     7501 gcgtacattg tagccatttc tttattaggt gttaagtaca caccaaatcc attagctgtt
     7561 ccgtttaaac ctttatgatc taaactaaat tcatcaaatt tattcatact tccatgaaac
     7621 aggcgataag ttccgcctgt ttcataattt tgttcattac tcataatttt tttcactcca
     7681 tttcaaaaga acgttctgct gtttttacag tcggcttttc caagttagaa ttttctggta
     7741 tcttgaaagt tccttcatcc atttcatatt ttactttagt tgcaaccaat ttataagcta
     7801 ccactgaagc cacctcttta tatgactcat tgtctattgt atctcttaaa tttgttcctg
     7861 acacagattc aaaatctgta atcgtatttt cgatttcttg tttatgagat tcgtaaaaat
     7921 cttccgcagt catacaagag tttaattctt ttacatcatt aatatttgtt tggttttcaa
     7981 tttcttcttg ccaacatttt tcattatagt aattgttagc attttcagat agattataaa
     8041 ccgcttcatt tataacaact gatcttagcg gttcgcttaa ttttaacgta tcatttttta
     8101 gttcatgatt ctcgcaagct ttcaaacttt ctacaacaaa cttttcaaca taatcacaat
     8161 tttcaggtga tcgatctaat agtaaacgat catgtttatt ttcacttgga ttctcaaaaa
     8221 ctacaccata aacatcacat acatcaaatt gtttcgtatc tgaataatat gtcacatagt
     8281 tttctcctat tttagctgta acatcataat tgctatgagt aagcttaata gaattttctc
     8341 catactttcc tctataataa tccaccatcg cttctaaata actaccgtgg attgttctat
     8401 ccggatcgtt aattgtacta tcgtagaaat tatgaaattc taaatctgat ttttgttgta
     8461 tctgctcttt attctcatta ggaacaaagg aattttttag tgcattaaat gctgtttgct
     8521 gttcttccaa gactttctta tcaatcgtac ttataaaatc aatagacgtt tctctaactt
     8581 cttgcattat ctgtctaaag ttttttggat caattttttc attattttta gtccaatttg
     8641 caatataagg aatagtaaag tctgacgtat caataccgta attgtgacaa acaataaatg
     8701 aagtcatttc cgcttgaaac tctttaatcg gtattgagta ggaagaaccg tgttcattct
     8761 tattgtgaag ctttttgtga gccaattcgt gaatactggt agtaagattt tgtgttctgc
     8821 tatttcttga atttaataca atttcttccc taccatcaac atattgaata tattcacctc
     8881 tagcgcttcc catttcacct ctaccagact cattcatatc ttttatagat atattcatag
     8941 attcggccaa atgatttaca cctttttcta attgactaac acttaattca ccatcaatat
     9001 taaaattcca taccctgtta ggaaatattt ttggcaaatc agcttcagtt gcattagttt
     9061 gggaaatatc aaatacgtaa cccttcttaa aatgcttgat ctttttgctt cttaattctc
     9121 catttttgat tttttctttt tgctcgcttg tcgcttcttt taacgtcttt tcctcaccat
     9181 tttcatcaat aaaaaccgtt accggagcat gcgcataaat gcctatccct ttttctttcg
     9241 ctttaacttg aaatcctagt tttttccaac catcataact tgctacagca attgctcctt
     9301 caaatccctc atcgatcaac gataggttta aaggactgta attgtgtatt ttagacatga
     9361 acttggcaaa ctcgatcata tcttcagggt tagactgata ttgctcgatt ttgctgttgg
     9421 aaaccttaat taaatcgtct agctcttttt gtttttgctc tttcgttttc ggtttccagt
     9481 ttcctttttt ataggccatc ttctatctcc tttctttttt aggtaagtta aattacctaa
     9541 ttaaattata ccagatatat aaaaactctt ctatctaatt taactgactt aatgcaaata
     9601 aaaaagagat aagatagtta tagtaaccat cttatccctt cttattttac catctactca
     9661 actatactta cgtttttacc tttactatct aattgaactt tgttatcttt agaagctact
     9721 ttagtaagca aaagttgatc caattcatca ttagaatatc ccgaataaaa attatctaaa
     9781 actttcgttg tggcaactgg aattgacaac ttcaaatcca tactagtagg ttcataagat
     9841 aattctcctt cagacgaaac ttcaccaaaa ctatttaaat tccaaatcgg actatctaaa
     9901 tatttataag ataatttaac ggtttccatt gaaggtgatt tgttttcatt atccatttta
     9961 attgttgctg ataccttttc ccactccggc tctgaatatt gaacaccatc gatctcttct
    10021 atatccgcct gtattttagg tatactatct tgaaaatcag caattttttg gtcattttga
    10081 aactcttgtt tttcctcatt ttctaattct gtttttacag aatctaaagt agcattatag
    10141 ctatcaatat cgcttttttt cttatcatta aacttttgtt tatcagcgtt caatgcttgt
    10201 tctattattt cttcatcact cattttagaa actttttcca atgtaagctg ttccatatcc
    10261 gttttaaata cttttgcttt gccattttta gtttggatca ccgcttttac atattcgttc
    10321 ttatcaatag gcgttttatt tttactactt gtttcgacta ccaaccaaca acgtgaatct
    10381 ttttgttctg cactatctat gaatgagata ttatgtgctt catttgactt agcaccagct
    10441 tcttctttac cacatgcaga taataatagc gcaaaactaa aaaacatagg tattgttgca
    10501 ataactctta actttttcat ttataagcac ctctttttta tcggtctgat acataatttc
    10561 atattatcat atttttattc caatacacag atactcttaa gataattgcc tgtagaaaaa
    10621 tatagcaaaa aacaaagaac caaataatca gtcctttgtt tatcactttt tttagttttc
    10681 cattatgtct actttatttt ttttaaattt tttactcatg ggatcgttga aagaaaggat
    10741 ttcatagtcg tactccttat ctactttcca atgatagaaa gaagggttat cttcagaagc
    10801 atattctgaa acacaattca ttaccaacaa atttaataga tcgtcagaaa cactatgttg
    10861 ttagtacaag taatctaaaa aattttctac tggaagcttt tagagcctaa aatatatttt
    10921 ttatttgatc caaaacttca gggaaataca aacctaatat caacacagca cctataatta
    10981 atagcggaat cattttctta ataaaagaga tcacagcaaa aactatcagt actgcaacta
    11041 atactaaagc tattttggga ttagaatata aaaactcttt gactgtagac gttacattta
    11101 agtatagttc aatcaatacg cgaaaatctc cattacttag tttatccata accgttctaa
    11161 aatcgatcat atcatttcct cactctttcc aattttattg cttcttttat tgaagaagca
    11221 acttgttcat tactatgctt atctatatat aatggggaaa agtaattttt atcaaaaaag
    11281 taatttgcaa aagctacatc gtcttctgtc ttccaattat aaaaacagta attcccacta
    11341 atcggtattt caaaaagccc ccaattctct agctccatgt tttctttttc aaacaacact
    11401 atgatttttt ttacatcttc tatagtttcc gaatcactgt taagtagctc acgtaaatat
    11461 atattttttg tattactgca cactatatcg aagtttttca taatttctat tctccgtttc
    11521 tactaattca ttcctatttc aaattcacgt gcttgtctca ttttctcttg ctctatcatt
    11581 cgttgcgcta cttcataatc atttttcgca cgatacatat ttaaatcatc attgattact
    11641 ctatcaattt ttctaataag ctttttatct ttaaattttt cagaaatctt cttgaagtgg
    11701 acttcatttt tttcacgtgc taattgtcgt tcttctaatc ttttttggaa atcatcataa
    11761 ctttgtttag catatttcgt tttaaattct ggtttttctc tatcaaactt aacgtttaat
    11821 ttttttccgt ctaatagatt tttaagttca ttacttttca aatttttttc ttcagattgc
    11881 tttaaaagtt tgatttgtcc tactacagca ttacccattc gagcattaaa atcttttttt
    11941 ctatttaaat aatattcttg tggattgtag cgtttaccgt aggttgtttg atatagctca
    12001 tcaatttctt tagtcatacg atcatattct tttctttttg gattatcctt tgtcatataa
    12061 tttgtgactt catcaatctt ttcttttgtt tcttcaggaa gctcattgta gccacgtgtt
    12121 gtactaggta tttctttttt taattccttt aggtacttta ctaattcttt gtcatatctt
    12181 gaattatttt ctacatataa ttgaatcaaa gaatctttta cagactgttt aagttctaaa
    12241 ggaacttctt ttctcaactt agaaatcttt tcaaactcgt tcgttctatc taatattttg
    12301 ctaccgaatt taaaaatcat atcgtctaac gtagactgtt ttctcttacc cctagcttgt
    12361 aaaacaccat catattccat tatttcacga gtatttttac gctccatagc tgttacatga
    12421 atatggatat gttcagtatt tctgtgaatc gttgcaaacc aaaaaggatc aactagttct
    12481 tccttttctt gcatttttcc catcatagat tttgttgctt catatagaat attttcattt
    12541 aattcatttg tttctggatt ataatatcct tcccttacta aaaaatcatt atcgaatgaa
    12601 attacatctt ggaacatcac cgatccatta ttttttgctt ctataaccga ttcttttatt
    12661 tttgaaatgt cttttttagt gatatatctt tttgtattac taaaagctcc gtttactatt
    12721 tcattatcta cattttctaa aatagctttt ttacgtgtca tataatcaat atatttatcc
    12781 atttcacgca aatctttaat cactggttga tctgtttcct gttctatttt ttccaaagct
    12841 ttttctattc tagctaattc atttagttca tcttcggaat aatcatgatc taatttatct
    12901 tgcctaatag cctcttgtct ggaaatgtaa tctacaaatt tttgaagttc taccatgtga
    12961 ttcttctttt tgttttttcc agtttcaaat tttgctttaa gaataatgct cgcacttttt
    13021 cggttaaaga tatgttcagt catatcatca cccaccaatt tcaaaatttt ttttctacag
    13081 gcggttttgt acttaatgct aagttgcatt agaatttttt agtgttcaat ccgttgtaaa
    13141 tcttaatgac ggtgaactaa acattgttcc atctcctaaa cgactacttt ctttttctgg
    13201 ttcagcacgc tcttcttcta attctttact agctaatcca ctattaatta atagtttata
    13261 gacagactct tctatactat ttaattgttc actataatct ttgtgtgtac tgtcttcttt
    13321 tttattaaag ttttcaagtt gctgtttttg caattctatt atcgtttcaa gttcgctaat
    13381 ttttaatttt gcttcttcta agtttttagc taactcttct ttttctggat cacggaaatt
    13441 ttgattggct tttgttaaca ttggtaaatt tgaaacaaca tatcggaaca tattagcttt
    13501 tgtttgaaat actgacttgt ttacttcaaa gcacttattg aatttttctt ttacatcttc
    13561 tgttgctgat actttgaaat aagggtagtt catttattta gatcactcct ttcgctaatt
    13621 aaaaaattga ataagcgttc ataaactgaa gttaactcgc taatactttc taccatttgc
    13681 tcatttgaca ataatagttt ttcaactact aaatcaaatt ctgacttttt ataatcaatc
    13741 aaatcaatct cactatcttg gcgaatgatt gctaaaaaat agtcattcct actaaacttt
    13801 tttccggtac gttcttgaat ttttttaact tttttatcaa tctcttttac atattgtgga
    13861 tcaatccctc taattgaaac gtccatatat acacctcatt caaatagttt ttatctatct
    13921 ggtatatatt attatatcaa agtctaaagg agaattaaag atttaaagac gaaaccaaag
    13981 aattaatgca aagagcataa gggaaaactg atagcacctt cctaaaggaa ggtggctaag
    14041 ttggctgtgc caactggttt tctttcaaaa tagcttcata ttttttgcta tcacaaaaaa
    14101 atccattttc gacctatttt cggtcataat atagtaccta cttttggtca tagtttcgtc
    14161 cgtagttttg gtcatagtaa ctaaagcttt tacgcccaaa aaaagagtgg caagttttac
    14221 cttgccactc tcttttctat tcacaaaatt ggtttaaatt cgcttttttt agcacttcgt
    14281 ttatatcata gcaatcataa tatttacaca acatcattcc taattttaac gcttgttcct
    14341 ctttatattt tttaagctct gcattttttt tgcgcttaat cgcttttctc ttttctttat
    14401 attccgcttc aattctcatt aattcttctt cagctttctc ttgaatagtg acaatagaat
    14461 tacacattct ctctaaactc ccttaaaata atttaaacac gatcactcaa atcggcttgc
    14521 agacttttct agttgcttta ttttttcctc aaattgtttg attttatttt cactttcctc
    14581 tattgaagat ttattatttt caatagtcgt ctgcatagaa ctgatttcat tttttgtatc
    14641 tgtttgttcg tctagggttt gaaattctaa gttttgatta gctttatcaa tatctttttg
    14701 cactacttta tttgctaaat tcattttttc aattgatttt ttctcatctt ttatagaatt
    14761 ttctatagct ttaatctgat atttaaaatt atctttttgc aaatcagaag tactttcaac
    14821 ttccaattta gcatttgatt taatatcttt gtctactgca tagaatttta tttccttttc
    14881 ttttaagtca tttgaaggtt ctaattcagg ataaatatat ctagggttaa ctgtcacaga
    14941 aattacacca aaatctttag gcagattttg ataataaatt accgtgtatt catctgacaa
    15001 ttttacaact tttgtcttaa catcttcatt atttttgttc gttataaaat ttaatttata
    15061 gtcactttta atattactta gtgatttagt acctgtatca tcttgatacc gcaatactaa
    15121 tttaaacagt ccggcttccc tatttatttc catatcatca acatacatat tcaaagaaga
    15181 cgttacattt tgggctgaac tcatttttac agtttcaaaa tcataacttt tccccatcac
    15241 ataaggagaa aaaacgatta tcattcctat tgctaaaaat ccaagtatag cacctaaata
    15301 taattttact cctttcgttt ttttatatac tttgtcaatt tgtgccttat tttttttatt
    15361 tggttccttc ttattatgaa tggaatattt cttattcata tacttcacct cactatttta
    15421 agtacttgat ttcataatta tctaccaaca cttggccgtc tttattggtt acttcaaaaa
    15481 gcatatagac tgtattttct gtatctccac tagaagattc tgttttataa tttacttcag
    15541 caaaataatt aatagtattg gcgttaacat aattcgtata taattttgaa tctttatatt
    15601 tacttttgaa tgttggatca cttgaatatg cttctccttt ttgagtagta gatttacttt
    15661 ctaaagtctt tttactcgtt gtaatcatgt cgtccggcac gatagaatca gctacagaag
    15721 gagtagctat tttctctaaa tcagctttct tttcttctac tttttcaata tcatataccg
    15781 gatatagctc aacaaatttc ttagcaactt cagcaatttg tttatttaat tcactgccat
    15841 catcattagt taagttcgct tctacatttg catttagatc actaatattt ttacttaact
    15901 tgctattttg ttcttctagt tgcgtaactt cttgatccaa ttttttattt tttgcttgaa
    15961 tgttacttgt atgaagttga gataataatc cgcctaaaac taaaataata agtaaaacac
    16021 cacaaatata tttccattta ttgtcatttt ttctcttaat catctatttt ttcctcctat
    16081 tttttgactc tgcgaatctc tggactatgt gattgccaat atgaatcttg ccaattatga
    16141 taaccaattc cgcttgaatt actgtcatac atagttgttt cattgacata aatacccacg
    16201 tgagaaatga aatcaggcgc tccatatgtt cctctaaaga aaatcagatc accagctttt
    16261 gcttctttaa ttgatactgc ttcagtcgct tcatactgcg ttactgtata actatctatc
    16321 gtaattccgg cgctaaattg ataaagataa gctgttaatc cgctacaatc aaaacctgtc
    16381 gttggatttt taccgcccca aacataaggc caaccttgat atttttccat ttctgttttc
    16441 atttttcccc aaaattctga aggattagcc ggattaccac tacccccacc gatatactgt
    16501 ttaactaact ctgcatagta aaaatttcca ccatttaaat acaaatatgt ttttccatat
    16561 ttaattgata cttcatttac atatgaataa gtctgtcctg tggtatttcc taaacttggt
    16621 gcaacaacat ttttagagta agcttcggcc gtttcgatag tatgtgtttt tttgtttttt
    16681 cctaagtagt gcatgtaagc tatgccataa ttgtaagctt ggactattcc atcatagtta
    16741 ctttccatgc cataactttt ggcaatgttg tacacattac tcaaatgttt aagcccttga
    16801 tcgatacttt cttcatattg aagtgtgttt acaggcaatc cggctgattc gctactttgc
    16861 attaaatccg gtaatttacc tccggattca cattgcataa ttgctaaagc ataaggtact
    16921 aattctttaa ttccgtattt ttcagcatat ttttctaccg ttttttgcca tttttgaact
    16981 tcaggtgaca acggtttgtt gccaccaatg acttctgcac ctcctgtatt agttgcagtt
    17041 tgtgttcctt gtaatgtagc taaagaacct ataactaaaa ggccaaccaa tgttatcagt
    17101 cctataacta cccctatttt tatttttaaa gcaagaccta ttttctttga tacttgcttc
    17161 atcccttgac gagcgagtgt tgaagcaaca ttattatttt tgttctgctc cattaaattc
    17221 acctccgatt tctattattg accaccatcg aatcgttcaa tttgctctgg atatggatca
    17281 aaattaatca tataggtgtc ttcactggaa gtttgaacta cagcttgtcc tacttctaat
    17341 tctggtaaaa gcataatttc tgtatcagta attgtatttc ctaaaacttt ttttatgtct
    17401 tccaacaatg cagaatctaa attaaagaag catttaaaag tacatagatt aaaaatgttt
    17461 ctaatcacat ctgctacttc tgatccagaa tctttaggga taatttcttc aggcgtttga
    17521 gttgcaaaat aaacacctgc acgcattttt cgcatttctc gctcaaaact tagtacatat
    17581 tcacaagcat acttgttatt tgaattgata
//
LOCUS       DACDLM010000059        16986 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.060, whole genome shotgun sequence.
ACCESSION   DACDLM010000059 DACDLM010000000
VERSION     DACDLM010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16986
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.060"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(517..954)
                     /locus_tag="IV356_002071"
     CDS             complement(517..954)
                     /locus_tag="IV356_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015737.1"
                     /translation="MMSKTKKVTSAGSNGSGNPFGIKSGSGGFNIGQQMLKGKAGIKS
                     TGDKRKSVRVPVELYDEVVKDLSYGAKYSLMTEILALFLKEFETHGNSIVTDFGKLKT
                     RPVKISEEAFKVLKVIKFETDQSNTNIIASALTWYLDKRKGKA"
     gene            complement(967..1821)
                     /locus_tag="IV356_002072"
     CDS             complement(967..1821)
                     /locus_tag="IV356_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAP9015738.1"
                     /translation="MMKSNFLGYVIAINMFKGGVGKSTLTQLMADILSARGFKVLVID
                     VDPQGTVTKKFQRQYDLKVVGKMTLFEAVINMSFLDCISPVKENLDIVLGSEQMSRFT
                     KVLRDMWRSTGFTDEGEEVFWNLFNYMIGNDNLRDQYDFILFDTIPTVSEFTDNVYVA
                     SDFLVIPTQTEQDSIDNLHSTVTNYQTAVKEVNGDLEILGIVPYLVDTKLKTGLELLS
                     ELQEEYGDLVYSHIVSERGVIKRWGREGLNKSIPHSKTAYSMYVDIVEETLVRLEKAT
                     GENILERV"
     gene            complement(1901..2137)
                     /locus_tag="IV356_002073"
     CDS             complement(1901..2137)
                     /locus_tag="IV356_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015739.1"
                     /translation="MLSDYKEELKLIENRVLGFVECKDNLDDTLEVLESIIFNTKVLD
                     LKAINGDMTTHIILDEISAKEIGETLIAWANKEL"
     gene            complement(2489..2713)
                     /locus_tag="IV356_002074"
     CDS             complement(2489..2713)
                     /locus_tag="IV356_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015740.1"
                     /translation="MISMARPRKYNTEEERKEAMKKARKKWVEKNQETIAYIRAKSFA
                     KKFIEMSEDEDIELLEKWLEDRKNNGQNDE"
     gene            complement(2825..3424)
                     /locus_tag="IV356_002075"
     CDS             complement(2825..3424)
                     /locus_tag="IV356_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015741.1"
                     /translation="MNLKNTNSNKSTLYVISDDYINKLKKVDYRVQNNYREQRLYFKS
                     NLKISNKNEEINYYVPLASAKENQRSLTNKSVFKIYGDREEKDFLGVLHINNMIPVPK
                     DCAKVWTPNSPNVDEKYKMLVIKQAKYLKLHESEINESCELLYNSKLGKLDPSYFKKN
                     RKEVITYQKIMTNVESLEAVSIAESQRNIHVQTQSIDVE"
     gene            complement(3742..6105)
                     /locus_tag="IV356_002076"
     CDS             complement(3742..6105)
                     /locus_tag="IV356_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HAP9015742.1"
                     /translation="MATVILAEKPDQAEKFAFALADKKIPKSGGKFEFQSEVFGDTIV
                     TWGIGHLVGLSMPEKYEWLPNKEKWDLANLPFLPKMDELKYEVSKGKSQQFAVVKACL
                     ENADQIIIATDPDREGENIAYNIFKLCKQSIFKKPMKRLWINSLVKSEIIKGFKNLRN
                     AEETISFFEEANARQIADYLVGMNYTELYTLKLQQKGLSGVVSLGRVQTPVNTLVVEN
                     DLSIKNFKSEKYKVIECHTVDREPKVIFKNSREYFNLDEFEADTKKYGLDSASIGIVK
                     SVEKTLKQVEPQKLFSLGGIQEYANKKWKYSAKKTDKIIQSLYDRGYLSYPRTDSELI
                     TTNEFEYLKANLDVYKSVLGISIDTPCLEPKKRFVDNDKVLEHYALIPTMDIPDIANL
                     TLDEKNIYEIVTRRACLMFAEPYKYENTKVTLDVNGLEFTTSGNVPISLGWKQVDTNL
                     DESDDKEETLPKFHEQETINIDIRFIDKLTKEPKRLTEGKLLGKTGIMAKLGLGTPAT
                     RSNIVDTLLNREYIKIENTNVYPTPKGYLLWDLTKNKDLLIGKPENTAIWEESLGKIA
                     QGSYTQEAFLRNIYNYINKTVSDLKKVEFTSDYLEKTVNQNKFDIGSYQVEEKKKVYS
                     ILNITSGEQFVIFKNISGKAINKKVLQELLLNNRTDKVLSGFKSKEGKAFNARLLFDP
                     NVMKVVMEFEKNSPKGDKKSKHDTVNGYEIVEKAKVFEIKELATGESFIFYKNNSGKT
                     LSSKTVKELLENGKTKEKVTGFISKDNKKYSAYLVFDNKNKVIKKEF"
     gene            complement(6120..6338)
                     /locus_tag="IV356_002077"
     CDS             complement(6120..6338)
                     /locus_tag="IV356_002077"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015743.1"
                     /translation="MELIPYAYQHLYKAKSMKDGNEVVGALICCPPFSYIATIESMKK
                     MCVDELNDGEVKNLKLTRVLERSIEEFR"
     gene            complement(6355..6714)
                     /locus_tag="IV356_002078"
     CDS             complement(6355..6714)
                     /locus_tag="IV356_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /protein_id="HAP9015744.1"
                     /translation="MNIDGIYNESDFKKGDIAVIRSEYDFPSEIGIHTVEGKTVCRYW
                     GRKGNLILLLDTDSGDKLKFCFWHNTNYCCEPIPKRLIDVDKESVRYLADGTRIRLTY
                     QKSENASITRVRDIVVI"
     gene            complement(6849..7148)
                     /locus_tag="IV356_002079"
     CDS             complement(6849..7148)
                     /locus_tag="IV356_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HAP9015745.1"
                     /translation="MVIKKYVYSHPINVFIIGKLGLSVEVFCELYGFKQGTLSSWITR
                     EREVADLPISFLYALSLASGGNMNEVYDCLCEYEKEYKEYLKISAPKRNKKYIED"
     gene            complement(7382..8983)
                     /locus_tag="IV356_002080"
     CDS             complement(7382..8983)
                     /locus_tag="IV356_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAP9015746.1"
                     /translation="MLNSCEYADVLAKILKNGIKQFNSKNLVAFKKNSNKIGAIAGFT
                     SKTNMIKTKGLIYRSIDRVLEDSDVLTHWTPNVYSWLGGGENKTIFGHKEANLIQINT
                     FVADIDYPVGEKKTDLNLLVLYLLEEGLLPTLIVDTPKGYHCYFLIQNYNQETDSFDK
                     ASYISNSNDFKSLRVAKRISENIRKSIQNRLPQVDMGCNHFGIFRFPTKKNIVHYEPN
                     FVDTFEGYLKWSKDFEEKEYALKRSNLSLLAPNSTGKKGSKRQIDTKWYDFLIHTDIA
                     EGDRNKTVFTLALACKSSGLSIGECMDQLDQLQFNNDLSYSEVERTIRSAYRGDYKGA
                     KSSYVNEIIENYATPTEFEKYSINVNRQAVKRKGNRVDPSNWVKFAKPREERKYSHFE
                     ESKADLLAYLERKQRSLKKNELFLSVSMGTISEETQIPVSTLKVILKELRTANTVILQ
                     TSRGRYGSTKIATSKFVEAKILSTVIQNKKDKQVFVLELLGTANSHVETILRRYEDKT
                     VPFHANILKEREKSKHAPIRGANTG"
     gene            complement(9381..9635)
                     /locus_tag="IV356_002081"
     CDS             complement(9381..9635)
                     /locus_tag="IV356_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015747.1"
                     /translation="MYNVGDQIDEIVKIGNVKLVKSKYYISETELIFNTESGCILIWK
                     LPFPKDETTLKKINTLKIRYCIHEIIDKNTYVINQVKVMG"
     gene            complement(10134..11018)
                     /locus_tag="IV356_002082"
     CDS             complement(10134..11018)
                     /locus_tag="IV356_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraA"
                     /protein_id="HAP9015748.1"
                     /translation="MKRFKGSRMSKKIGKESLSLGLKKEIFKFKNMYSEPEFRLIFQL
                     DIVRGLKISFSCLGYLVWLFIARVGWSNAYSFYKLFAGTDRLKESLEVKEALNILGSL
                     AFSLFIFALFILQVGKIMMSKNDNYINYLKPFQKGIKIICRQGTVLFLLSLYEHEIHF
                     QNYYNTTTKLGAFLLLYLVSNIAEKMLFKHIVKQVFSDIQKESYCLKTPYGNLKNVEL
                     FLFKMDSKWDKYIYRSKEVFLTGSYNETLQESLYDTGAIFNNEPMVLKDFFGDYELVW
                     NPKQLSEQGAEDEFAEVH"
     gene            complement(11005..11568)
                     /locus_tag="IV356_002083"
     CDS             complement(11005..11568)
                     /locus_tag="IV356_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015749.1"
                     /translation="MTAIYKALKNSNVSEYVKSRVLNNNLDYILENGVADLISKLSDP
                     IDIDHLVVWQDGTLEVSIYGEFYSRNKVTTFKNSISGREDLKGINKNSKFYRTNKELL
                     EKISKRVFELVNPFSKKRSKELFGIFYDGFSAKSNVEKFFYFNDSAYIAVKDSKRIPE
                     ATLEYLEPIKLSVFYSLYEKEIADEAV"
     gene            complement(12064..12372)
                     /locus_tag="IV356_002084"
     CDS             complement(12064..12372)
                     /locus_tag="IV356_002084"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015750.1"
                     /translation="MKLEIKEVVCDWGIYVDGETYPFMIFNSKANAQEIMRIMELDNK
                     HERFDEVNKMENECEAVEYQKTCANNKYILGAMGLGKSASIKQVYEESQENCVYENSN
                     "
     gene            complement(12540..12932)
                     /locus_tag="IV356_002085"
     CDS             complement(12540..12932)
                     /locus_tag="IV356_002085"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015751.1"
                     /translation="MNQQVNWVNDFEKEFRLKFFGNPTAESTEEKNVVYFENTRNTEW
                     AVKIDQNIKVITIGKLKSNNFEIGEREKQMIDFLLSHSKKWHEIGLKESNNSIEVKNI
                     TNKLFQIEVKYGEKEKPNVFGNYDWSEF"
     gene            complement(13092..13703)
                     /locus_tag="IV356_002086"
     CDS             complement(13092..13703)
                     /locus_tag="IV356_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP9015752.1"
                     /translation="MLVGYARVSSDDQNLERQLEEFKKIGVEKVFAEKKSGRNTVERP
                     EFNKMLSFVREGDTLVFESLERLGRNSDEILETVSFIDKNGMGLMVLNLPILDTKFGD
                     PNLEKLVRSLVINIFSWTAQNEREEIKRKQKQGIAIAKKKGVYKGKPYEYSSTAKNPQ
                     KRFIYNEIVRMLGEGVPIKRIAEKTGTNRNLVYRIKKRISESD"
     gene            complement(13743..14525)
                     /locus_tag="IV356_002087"
     CDS             complement(13743..14525)
                     /locus_tag="IV356_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP9015753.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSDTFSLDKDYELLNPIIKNIFTKYYSKDFEDYRDIEVKPDPKKVGRKIRSIRK
                     KLGLTMQEFGCEVSNSPRSTVSTWEHGGNLPNKAKLRKIADIANCSVEDLLFDEGFIS
                     KQSKVKLINELKEENSKLKEKIKYYECLFDGIESLLNSRKNS"
     gene            complement(14539..15921)
                     /locus_tag="IV356_002088"
     CDS             complement(14539..15921)
                     /locus_tag="IV356_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP9015754.1"
                     /translation="MKPNLSLTSKRIRKIIESKGLTLEQFGDLIGDTPISSVNNWLRG
                     VSLPNKNRLLTIANIGNTSADWIKWGTLEEYIASYLIDSGYELYIKDFPEIPHKVFKD
                     IQEKYSDTFSLDKDYELLNPIIKFNIGGVTLNRIKFYIDSSKKTIKQISTETGINYTT
                     LTNYYRGERNPRNTETWNILADYFHVPVSYLMGLDETNVELKNLNIGDNIKSTRKSKK
                     MTQNDLAIKASISRSYLADVEGDRYNPSIETLDSIARALDVPIVALINDSSTDNIVEP
                     YESLTAENILLKQENEELKYEVESLRKRLYEIQQVVNQGAEKMIPNLKDVSKRIKYIR
                     KKLGMTMEQFGSHLSNSPKSTIATWESGRNIPSQKKLQLIAIVGETTTDWIKWGTLEE
                     YITSYLIGIGYELYIKDFPEIPHKVFKDIQEKYSDTFSLDKDYELLDSIIKNIFTKYY
                     SKEFEVNQIP"
     gene            complement(15970..16845)
                     /locus_tag="IV356_002089"
     CDS             complement(15970..16845)
                     /locus_tag="IV356_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP9015755.1"
                     /translation="MKPNPVETGKRIKSIRSNFGMTMEQFADLIGNAQKGNINNWERG
                     FSLPNKERLIKIAELSNKTIDWIKWGTLEEYIASYLKDSGYELYIKDFPEIPHKVFND
                     IQERYSNTFSLNKDYELLNPIIKNIFTKYYSKDFEDYRDIEVKPDLGLTDDNKNIKMI
                     GQRIRKIRKKENITLEEFGKLFSPTADKAVISNWENGKNLPNSERIKKIAEIGGVSEL
                     YLMTGVDSSVAESMYFLSEVALDALERLSIEEVNRIIESFAGYLNVISKIDDPDKREI
                     SLNAICQLSLLDKMG"
BASE COUNT         5269 a         3142 c         2031 g         6544 t
ORIGIN      
        1 aaggtttctt caaagaaagg agcaaaaatc ccacttatga aaaacgaaat aaacgttact
       61 aattcagtta cattgtcttt tctttgatta acaaagacca acgctatcat cgaaaggaat
      121 aaatttacta caagaagaac taatgtatag cctattatcc ttttccaata aattttaata
      181 tcttctaaaa tctgcataat tagttaatct gcataatgat ataaatagct gtcgctatta
      241 aaattaggta cgaccacttt ccaagcaaag aatatacagg cgaccagaaa aaagagagta
      301 ctttaaacat aaaccagatt atcaatatat agccaaaaaa actccaaaaa ttagggacaa
      361 accaattgat aaatactaaa gcattaggaa ttatagccca tttaaccaat gcaataattc
      421 cacctaccag tagaaaaacg gctactacat acttccaaat ataattttct ttgtatgaat
      481 aatttgattt atgatccata gtcttacctc atttcattat gcttttcctt ttcttttatc
      541 aagataccat gtcaaagctg aagcaataat attagtatta gattgatctg tttcaaattt
      601 tataactttc aaaactttaa aggcttcttc agaaattttt actggtctcg ttttcaactt
      661 gccaaaatca gtaactatac tatttccatg tgtttcaaat tcttttaaaa ataaagctaa
      721 aatttctgtc attaatgaat atttagcccc gtatgataaa tctttaacaa cttcatcgta
      781 taattcaact ggtaccctaa cagatttccg tttatcacca gtagacttaa tgccagcttt
      841 accttttaac atttgttgtc ctatattaaa tccaccacta ccgcttttta ttccgaacgg
      901 attacccgaa ccattactgc cggcactagt tactttttta gttttcgaca tcatgcaaca
      961 cctttcctaa acacgttcta aaatattttc tcctgtagct ttttctaaac gtactaacgt
     1021 ttcttctaca atgtctacat acatgctata agcagtttta gaatgtggga tagatttatt
     1081 tagtccttct ctaccccaac gtttaattac gcctcgttct gaaacaatat gagaataaac
     1141 taagtctcca tattcttctt gaagttctga taaaagttct aatcctgttt ttaatttagt
     1201 atccactaga tatggaacaa tacctaaaat ttctaaatct ccgtttactt cttttacagc
     1261 agtttgataa ttagtaaccg tactatgcaa gttgtctata gaatcttgct cagtttgcgt
     1321 gggaattact aaaaaatcac tcgccacgta aacgttatct gtaaattctg aaactgtagg
     1381 aatagtgtca aacaaaataa aatcatattg atctcttaaa ttatcattac cgatcatata
     1441 attaaacaaa ttccaaaaga cttcttcacc ttcatcagta aaaccagtac ttctccacat
     1501 atctcttaat actttggtaa accttgacat ttgttctgaa ccaagcacaa tatctaagtt
     1561 ttctttaaca ggagaaatgc agtctaagaa agacatatta attactgctt caaacaatgt
     1621 cattttccca acaactttta aatcatattg tctttgaaac tttttagtta ctgttccttg
     1681 tggatcaaca tcaataacta aaactttaaa gcctctagcc gatagaatat cagccattag
     1741 ctgagtaaga gttgacttac caactccccc tttaaacatg ttgattgcaa ttacatatcc
     1801 caaaaaattt gatttcatca tgtatacctc acttttgata atttattata ctatacagac
     1861 tacttgtagt caattggcca ctttatttta aaattatctt ttacagctct ttattagccc
     1921 atgctattaa agtttcgcca atctcttttg cgctaatttc atctaatatg atatgtgttg
     1981 tcatatcacc attaattgct ttcaaatcca gaactttggt gttaaatata atactttcaa
     2041 ggacttctaa agtatcgtct aaattatctt tacactctac gaaccccagt actctattct
     2101 ctatcaactt tagctcctcc ttataatcag ataacaaaaa aattctctaa aagtcctaca
     2161 aaaaaatcta gtaaaaaagg tcaaaagtga acgattcatt aatataattc gttattttcc
     2221 attatgagcg gttttgtaat aatttcaata tttttttcta cgcttgaaca atacatagat
     2281 attaagaaaa tatttagtga aatttatcaa cgctcattta ataaatcgtt cctcaaaata
     2341 ttcatattcc tcctttcttt aggccataat cgtctgtttt tattcccgat ccctctatcg
     2401 actacttgta gtcattagac ttttagaaaa gggatatttc tatccctaaa accattctac
     2461 accattgact acttgtagtc aatggttatt attcatcatt ttgaccgtta tttttccgat
     2521 cttctaacca tttttccaac aattcaatat cttcatcttc agacatttca atgaattttt
     2581 tagcaaatga tttggctctt atataggcaa tagtttcctg atttttttca acccattttt
     2641 tcctagcctt tttcattgct tcttttcttt cttcttctgt attgtatttt ctcggtctcg
     2701 ccatagaaat catcctttaa gttttatctt ctacagtata ataacattta aatacatatt
     2761 cgattaaaat tcaatgtatc ataatatcca atagaataat aaaataagat aggtttagcc
     2821 tatcttactc tacatctata ctttgagttt gtacatgaat atttctttgg gattctgcta
     2881 tactaacagc ttccaatgat tctacattcg tcattatttt ttgataagta attacttctt
     2941 tacgattttt cttaaagtaa ctaggatcaa gtttacctaa cttagaatta taaagtaatt
     3001 cgcatgattc atttatttca gactcatgta atttcaaata ttttgcctgt ttgattacta
     3061 acatcttata cttctcatca acatttgggc tattaggtgt ccatactttt gcacaatctt
     3121 ttggcacagg aatcatatta tttatatgaa gtactcctaa aaagtccttt tcttctcgat
     3181 caccataaat cttaaacact gatttattag tcaaagaacg ttgattttct tttgctgaag
     3241 ccaatggtac ataataattt atttcttcat ttttgttaga aattttcaag tttgatttaa
     3301 aatataatcg ttgttctcga tagttgtttt ggacacgata gtccaccttt ttcagcttat
     3361 ttatataatc atctgaaatt acatatagtg tagatttgtt tgagtttgta ttctttagat
     3421 tcattggatc tccccctttc caatggatta tatatgctaa gattaacagc ctataatctt
     3481 ttttaaaact aattgctctc attttacatt taattcataa aaatatattc acgtttatgt
     3541 aattttattg gtaaaacaca ctatacatat caaaacggta ttattctact tccaatttaa
     3601 caaaatagca atctaatttg tttgtatttt ttcaactgtc ctctaactag ttttgtattt
     3661 atccttaatt cagtatacct atattttggg cacttttgaa taaaaataag cggaaaaaca
     3721 aatgatttcc gccactaaga attaaaattc tttctttata actttgtttt tattatcaaa
     3781 gacaagataa gcactatatt ttttattgtc tttacttata aaacccgtta ctttctcttt
     3841 agttttccca ttttctaaca attctttgac tgtttttgaa cttaaagttt tcccactatt
     3901 atttttatag aaaataaaac tttcacctgt tgctaattct tttatttcaa atacttttgc
     3961 tttttcaact atttcataac catttactgt atcgtgtttg ctctttttat cgccttttgg
     4021 actgttcttt tcaaactcca ttaccacttt catcacattt ggatcgaaaa gtaatcttgc
     4081 attaaaagct tttccttctt ttgacttaaa gccggaaagg actttatctg tacgattatt
     4141 tagtaatagt tcttgaagaa cttttttatt gattgctttt cctgatatat ttttaaatat
     4201 cacgaactgt tcaccactag taatatttaa aatagaataa acttttttct tttcttccac
     4261 ttgataacta cctatatcaa atttattttg atttacagtc ttttctaaat aatccgaagt
     4321 aaattctact tttttcaaat ctgaaacagt cttattgata tagttataga tatttcttaa
     4381 aaaagcttcc tgtgtatagc taccttgcgc aattttccca agtgattctt cccatatcgc
     4441 tgtattttct ggttttccaa tcaataggtc tttattcttt gtcaaatccc ataataaata
     4501 tccctttgga gtaggataaa cattcgtgtt ttctatctta atatattccc tatttagaag
     4561 agtgtctaca atattagaac gtgtagcggg cgttcctagc cctaatttcg ccataatacc
     4621 ggttttacct aataatttac cttcagtcaa ccttttaggt tccttagtta atttatcaat
     4681 aaatctaata tctatattta ttgtctcttg ttcatgaaat ttaggtaatg tttcctcttt
     4741 atcatcagat tcatctaaat tagtatctac ttgcttccaa cctaaagata taggtacatt
     4801 accacttgtg gtaaattcta agccgtttac atctaatgta acttttgtat tttcgtactt
     4861 gtaaggttct gcaaacatta gacacgcacg cctagtaacg atctcataaa tatttttttc
     4921 atctaatgtc agatttgcta tatcaggaat atccattgtt ggtattagtg cataatgctc
     4981 taatactttg tcattatcta caaaccgctt tttaggctct aaacaaggtg tatcaatact
     5041 gatccctaaa acactcttat acacgtctaa attcgctttt aaatactcaa attcatttgt
     5101 agttatcaat tcactatcgg ttcttggata agataaatat ccacgatcat atagactttg
     5161 gataatttta tctgtttttt tagcagaata tttccatttt ttattagcgt attcttgaat
     5221 cccccctaaa ctaaataatt tttgtggttc tacttgcttc aatgtttttt ctactgattt
     5281 tacaattcct atactggcgg aatccaaacc gtatttttta gtgtctgctt caaattcatc
     5341 taaattgaag tattctcgac tatttttgaa tataactttt ggctctctgt caacagtatg
     5401 acattcaatc actttatact tttcagactt gaaattttta attgataaat cattttcaac
     5461 aaccaatgta ttaacaggtg tctgaaccct acctagtgat accaccccag ataagccttt
     5521 ttgttgcaat tttaatgtat acaattctgt ataattcatt cccactaaat aatctgcaat
     5581 ttgtcgtgca tttgcttctt caaagaaaga aatagtttcc tctgcatttc taaggttttt
     5641 aaatcccttt attatttcac ttttaaccaa agaattaatc cacaaccgct tcataggctt
     5701 cttaaaaata gattgcttac acaacttaaa aatattataa gcaatattct ctccttcacg
     5761 atctggatca gtggctataa taatttgatc agcattttct aaacacgcct taactacggc
     5821 aaattgctga ctctttccct ttgaaacttc atacttcaac tcatccattt ttggtaaaaa
     5881 aggaagatta gctaaatccc atttttcttt gttaggtagc cattcatatt tttccggcat
     5941 tgataatcca actaaatgtc ctatccccca agttacaatc gtatctccaa atacctcact
     6001 ttgaaattca aacttccctc cactttttgg aattttctta tcggctaacg caaaagcgaa
     6061 tttctctgct tgatctggtt tttctgctaa aattacagtt gccataaata ctctctcctt
     6121 cacctaaatt cttcaattga acgttctaat acacgtgtta attttaaatt tttaacttca
     6181 ccatcattca attcatcaac acacatcttc ttcatagatt caatggtagc aatataagaa
     6241 aatggtggac aacaaatcaa cgctccaaca acttcattac catctttcat tgatttagcc
     6301 ttatacaaat gttgatacgc ataaggtatt aattccataa tccttcacct cccactagat
     6361 tacaacaata tctcttacac gagtaattga agcattttca gacttctgat acgttaatct
     6421 aatcctagtt ccatcagcta aatatcttac actttcctta tctacatcaa tcaatctttt
     6481 tggaataggt tcacagcaat aattagtatt atgccaaaaa caaaacttta atttgtcacc
     6541 tgaatcagta tctaataata atattaaatt cccttttcta ccccaataac gacaaacagt
     6601 ttttccctct actgtatgga ttcctatttc tgaaggaaaa tcatactctg aacgtattac
     6661 cgctatatcg cctttcttaa aatctgattc attataaatc ccatcaatat tcattaatag
     6721 cccccttttt ttatttacct gatatatatt aattctaaca aaaaaacagc caatatcaaa
     6781 ctatcaaaaa acagagtagc tatcagtcta cttgtagtca aaaagcaaat tattcttttc
     6841 ttctttctct aatcttcaat atatttttta ttccgttttg gggctgaaat tttcaaatac
     6901 tctttatact ctttttcata ctcacacaaa caatcataaa cctcattcat attccctcct
     6961 gaagctagag acaaagcata caaaaaagaa ataggcaaat cagctacctc acgctctcta
     7021 gtaatccaag acgatagagt tccttgttta aatccatata actcacaaaa cacctcaaca
     7081 gataaaccta gcttaccgat aataaataca ttgatcgggt gtgagtaaac atatttctta
     7141 attaccacag aaaatcttcc tccttcaaac ataactgcat acgcagttat aagctgtatt
     7201 ccgtacacgt ggattaaggg aaaagacaca agtaaaaata gttctatgca ctccatacgt
     7261 aaaagagagt actaactact aatgattagt atacgttaaa acaggaatag gagtgagcag
     7321 aaacactaga tatgttaatt ggcaatttag ctatttaaaa atcaaaaaaa taaatagaac
     7381 tctaacctgt attagctcct ctaattggcg catgtttgct cttttctctt tctttcagta
     7441 tgttcgcatg gaacggtact gttttgtctt cataacgtct taaaatcgtt tctacgtggc
     7501 tatttgctgt tcctaataat tctaagacaa atacttgttt atctttttta ttctgaataa
     7561 ctgtacttaa tattttagct tccacaaatt tgcttgttgc tattttagtc gatccatacc
     7621 gaccacgaga cgtttgtaat atcactgtat tcgccgttct aagctctttt aaaatcacct
     7681 ttaacgtaga tacaggaatt tgtgtttctt cagatatagt tcccatagag acacttaaaa
     7741 acaactcatt ttttttcaat gatctttgtt ttctttctaa gtaagctaat aaatcagctt
     7801 tactttcttc aaaatgacta tattttcgtt cttctctagg tttagcaaat ttcacccaat
     7861 tagacggatc gacacgattc cctttacgtt taacagcttg tctatttaca tttattgagt
     7921 atttttcaaa ctcggtaggt gtagcataat tttcgataat ttcattgaca tatgaacttt
     7981 tagcaccttt gtaatcgcca cgataagcac ttcttattgt tctctcaact tcagaatagg
     8041 acaaatcatt attgaattga agttgatcca attgatccat acactcgcca atagataagc
     8101 cacttgattt acatgccagg gctaaggtaa aaacagtttt atttctatct ccttcagcaa
     8161 tatccgtatg aattaaaaag tcgtaccatt tagtatcaat ttgtcgttta gaccctttct
     8221 tgccagtaga attaggagct aataatgaca agttagacct ctttaaagca tattcttttt
     8281 cttcaaagtc ttttgaccat ttcaaatacc cttcaaacgt atctacgaaa ttaggttcat
     8341 aatgtacaat atttttttta gttggaaatc taaaaatacc aaaatgatta cagcccatat
     8401 cgacttgtgg taaacgattt tggatagatt ttctgatatt ttctgatatt cttttagcaa
     8461 ctctcaaaga tttaaaatca tttgaattag aaatatagct tgccttatca aatgaatcag
     8521 tttcttggtt atagttttga atcagaaaat agcaatgata accttttggc gtatctacaa
     8581 tcagtgtagg caataaccct tcttccaata gataaagaac tagtaaattc aaatccgttt
     8641 tcttttctcc tactggatag tcaatatctg ctacaaaagt attaatctga attaagttag
     8701 cttctttgtg accaaaaatt gttttgtttt caccgccacc aagccatgaa tacacgttag
     8761 gagtccagtg tgttaataca tctgaatctt ccaagacacg atcaatagaa cgatatataa
     8821 gacctttagt ctttatcatg tttgttttag aagtaaatcc ggcaatagca ccaatcttat
     8881 tgctattctt tttaaaagca actagatttt tgctattaaa ctgtttaatt ccatttttaa
     8941 gaattttagc taaaacgtcc gcatactcgc aactattcaa cattgcactt tctccttgct
     9001 atcaattttg aatagcaaaa aagacatagg gtaactttag attccgtaat aaggagtcct
     9061 aaaattacac tatgtcttta gagtaagcac ttaaatgcta aactttaaac gtgcaaaaat
     9121 taaaatgagt tggtagctca tcttggtgga cttcgtggat tgccaaatcg cttttcttac
     9181 tacagaagtt ccattaaata agattggtag tcttatttaa ttatcttttt cgctattttt
     9241 ttcgttacat tcatacatag tagagagtct gtaactaact tttctactag aattttttag
     9301 tgttcctttg gcttcagaac taataccaat attataagct aatagaatta cttttaacaa
     9361 gagttttttt taaaagattt ttaccccatc acttttactt gatttataac ataagtattt
     9421 ttatcaataa tttcatgaat gcaatatctt atttttaaag tatttatttt tttcagtgtt
     9481 gtttcgtctt tgggaaaagg cagtttccaa attagaatac atcctgattc agtattaaaa
     9541 attagttcag tttctgaaat atagtactta cttttaacaa gtttaacatt acctattttt
     9601 acgatctcat ctatttgatc tcctacgtta tacatttttg tttctccttt cttgatatac
     9661 atattatatc accttgacta caagtagtca acttggaaca aaagaaatag tctacttgta
     9721 gtcatgtttt caattggaaa aaaatttatt taaagattct tttaaggaaa cgcttaaaca
     9781 atatttctta gcttttttac ttgcaaattc aggaaaatga ctgtataatc atttatataa
     9841 attatgaaat aaagacttcg tggattgcca aagatttttc ttactacgaa cagtcttacg
     9901 agtcaacgat tgttggtagc tttcgttggc tctttatttt tgccacaaaa gactacttgt
     9961 agtcttttgg aatttcattt tcaggctact tgtagtcaaa aaaaaaggaa agacattttc
    10021 attgtctttc ctttttttta cgatctttcg ttagtcttct gtacggccca atcgttctta
    10081 tactttcttt tgaaggcgtt cttctttcag ataatgtttt tctgtacact atgttagtga
    10141 acttcagcaa attcatcttc tgccccctgt tcactaagct gttttggatt ccaaactagt
    10201 tcataatctc caaagaaatc tttcaaaacc ataggttcat tattaaatat tgctcctgtg
    10261 tcgtacaggc tctcctgaag agtttcgtta taactaccag ttaaaaatac ttctttactt
    10321 ctatagatat atttatccca cttactatcc attttaaata aaaacagctc aacatttttt
    10381 aaatttccat aaggtgtttt taaacaatag ctttcttttt gaatatcaga aaagacttgc
    10441 tttacaatat gtttaaacag cattttttca gctatattac taactaaata taggagtaaa
    10501 aatgcaccaa gtttagttgt cgtattataa taattttgaa aatgaatttc atgctcatac
    10561 aggctaagta gaaataaaac tgtgccctgt ctacaaatga tttttattcc tttttgaaaa
    10621 ggcttcaaat aattaatata attgtcattt tttgacatca ttatttttcc tacttgtaag
    10681 ataaataaag caaaaataaa caggctgaaa gcaagacttc ctaaaatatt taaggcttct
    10741 ttcacctcta atgattcttt taatcgatca gttccggcga acagtttata aaagctataa
    10801 gcattgctcc atcctactct agcaatgaat agccaaacca gataacctaa acaactaaaa
    10861 ctaattttca gccctctcac tatatctaat tgaaaaatga gtctaaattc cggctcacta
    10921 tacatatttt taaatttaaa aatttctttt ttcaatccga gcgataacga ctctttgcct
    10981 atttttttac tcatcctact ccccttaaac cgcttcatca gcgatttctt tctcataaag
    11041 tgaataaaaa acagacaatt taattggctc taaatattct aaagttgctt cagggattct
    11101 tttactgtct ttaaccgcaa tataagctga atcattaaaa taaaaaaatt tttctacatt
    11161 actttttgca ctaaaaccat cataaaaaat tccaaaaagt tctttactac gtttttttga
    11221 aaatggattc accaattcaa aaacacgctt tgaaattttt tctagcaatt ctttatttgt
    11281 cctatagaat ttactatttt tattgattcc ttttaaatct tctcgaccac taatactatt
    11341 tttgaatgta gttactttat ttctactata aaattctcca tatattgata cttctaaagt
    11401 accatcttgc cataccacca aatgatctat atctatagga tcacttaatt tactgattaa
    11461 atcagcaaca ccattttcta aaatgtaatc taaattatta tttaatactc tcgacttaac
    11521 gtactctgat acgttagaat tttttagtgc tttataaata gctgtcattc tttattctcc
    11581 ttcgtagcct tttgatctac gaatttaact accctttttc tatatacaac cctcctcatt
    11641 caaaattaga tagtcaagac gcttaacaag actacatttc tattttgtat gatttaccgc
    11701 tataattcaa cctcaattaa aatttatttc gtgcctaacg atttaaatat tcagttactt
    11761 tctttattaa aaacagcaaa ctataaatga taataaaatc aaacactatt aaaatcatac
    11821 ttgatattaa agctttattt gttaatgttg taatcccaat agtaattact attaagtttg
    11881 tgattataat tctaccaata ttactatttt cattcttatg aattagtaaa tcatagacat
    11941 caaatacgat aatacaaact attaagaaca atataaatat taccttattg ttatatacaa
    12001 attcagttga ttttcctatt aagtataaaa ctaaataaat tagctcccac atattctcac
    12061 tctttaattc gaattttcat atacgcaatt ctcctgtgat tcttcgtaga cctgtttaat
    12121 agaagctgat ttacctaatc ccattgcacc taaaatatac ttattattgg cgcatgtttt
    12181 ttggtattcc actgcttcac attcattctc cattttgttt acttcatcaa atctttcgtg
    12241 cttattatcc aactccatga tacgcattat ctcttgtgca tttgctttac tattaaaaat
    12301 cataaatgga tatgtttctc cgtctacata aattccccaa tcgcagacaa cttctttgat
    12361 ctctaatttc ataaaaaaca ccttcctgta gataatcaat taacactcat gcttatcaac
    12421 tgattcttga atggtattgc aaggaaatgt attgaatctg ttttcgtcac attctaacat
    12481 tgtatactgt ggcgtaagag aactattatc ttcaacactt attgaatcga atatgcaacc
    12541 taaaattctg accagtcata atttccaaaa acattaggct tctccttttc tccatattta
    12601 acttcgattt gaaaaagttt attagttata ttttttactt ctattgaatt gtttgattct
    12661 tttaagccaa tctcgtgcca ttttttactg tgtgacaaaa gaaagtcaat catttgtttt
    12721 tctctctctc ctatttcaaa attattgctt tttaattttc caattgttat aactttgata
    12781 ttttggtcta ttttgacagc ccattccgtg tttcttgtgt tttcaaaata gactacattt
    12841 ttttcttctg tactttctgc tgtaggattt ccaaaaaatt tcagtcgaaa ttctttttca
    12901 aaatcattaa cccaattaac ttgttgattc actctcgcat agcctctttc ttttctattt
    12961 ctgtcgttac ttgactgcca caaaattaat tcttttgttt agaagcttct ttgtataatt
    13021 gtacacctta aaagtttgaa acaggcttag aatccttctc tcgtaacatt gatttctcaa
    13081 agaacttaaa atcaatcaga ttcacttatt cttttcttta ttctatagac taaatttcta
    13141 tttgttcctg ttttttctgc aattcgctta atcggaacac cttctccaag cattcttact
    13201 atttcattat agataaacct cttttgtgga ttctttgcag tagaagaata ttcgtagggt
    13261 tttcctttat agactccttt cttcttcgca attgctattc cttgtttttg ttttctctta
    13321 atttcctccc tctcattttg agccgtccaa gaaaaaatgt taattactaa gcttctaaca
    13381 agtttttcta agtttggatc accaaatttt gtatctaaaa ttggtaaatt caaaaccatt
    13441 aagcccatac catttttatc tataaaagat actgtttcta gtatttcatc agaatttctt
    13501 cctaagcgtt caagcgactc aaaaacaagc gtatcccctt ctctgacaaa tgacaacatt
    13561 ttattgaact ctggccgttc tactgtgtta cggccagatt ttttctcagc aaatactttt
    13621 tcaacaccaa tttttttaaa ttcttcaagc tgtctttcca aattttgatc atctgaactg
    13681 actcgtgcat aacccactaa catatttaac acctacaaat aattttactc tagtttaatt
    13741 aactaggaat tttttcgtga gttcagcaga ctctctatac catcaaataa acattcatag
    13801 tattttattt tttcttttag ctttgaattt tcttctttga gttcatttat caatttaact
    13861 ttggattgtt tagaaataaa gccttcatca aaaagcaaat cttctacact acaattcgca
    13921 atgtctgcaa tttttcttag tttggctttg ttgggtaagt taccaccatg ttcccatgtt
    13981 gacacagtgc ttctaggaga attagaaacc tcacacccaa attcctgcat agtaaggcct
    14041 aatttttttc taatagaacg aatttttctc cctacctttt tagggtctgg tttaacttct
    14101 atgtctcgat aatcttcaaa atcttttgag taatattttg taaatatatt ttttattata
    14161 ggattcaata actcatagtc tttatctagc gaaaacgtat cactatatct ttcttggatg
    14221 tctttaaaga ctttgtgagg tatctctgga aagtccttaa tatatagctc ataccctata
    14281 tcgataaggt atgaagttat atactcttct aatgttcccc atttaatcca gtcaattgtt
    14341 gaattagtga tagttgacaa taatttcagc ttttgtggat ttggcaaatt ggtcccacgt
    14401 tcccagttgg atatggtcgc acgtggtgaa ttatctattt tccttccaag ttcttccata
    14461 gtaaaaccac atgaaaggcg taattgttta attcgttttc ctgcttctga aggattcggc
    14521 ttcatacaat cacctctctt atggaatttg gtttacttca aattcttttg agtaatattt
    14581 tgtaaatata ttttttatta tagaatccaa taattcatag tctttatcta acgaaaacgt
    14641 atcactatat ttttcttgaa tgtctttaaa gactttgtga ggtatctctg gaaagtcttt
    14701 aatatatagc tcatatccta taccgataag gtatgaagtt atatactctt ctaaagttcc
    14761 ccatttaatc cagtcagtgg tggtttctcc tactatagca atcagctgta actttttctg
    14821 agaaggtata tttctaccac tttcccaagt agcaattgta cttttaggtg agttgcttaa
    14881 atgagaacca aattgctcca tagtcatacc taattttttt ctgatatatt taattctttt
    14941 acttacgtct tttagattgg gaatcatttt ttcagctcct tgatttacta cttgttggat
    15001 ttcatacaat ctttttcgta agctttctac ctcatatttt aattcctcat tttcttgttt
    15061 aagaaggata ttttcggctg tcaaactttc atacggctct actatattat cagtagaaga
    15121 atcgttgatt aatgctacta tcggaacgtc caatgctcgt gctatggagt ctaaagtttc
    15181 aatactaggg ttatatcgat ctccttctac atcggcaaga taagagcgag agatactagc
    15241 tttgattgct aaatcatttt gtgtcatttt tttacttttt ctagtgcttt taatgttatc
    15301 tccgatatta aggtttttga gttcaacatt tgtttcgtct aatcccatca aataacttac
    15361 aggaacatgg aaataatcag caaggatatt ccatgtttca gtatttctag gatttcgctc
    15421 accacggtaa tagttcgtaa gagttgtata gttaatacca gtttctgtac taatttgttt
    15481 aatggtcttt ttactggaat caatataaaa ttttattcta ttcaaagtaa cgccccctat
    15541 attaaatttt attataggat tcaataactc atagtcttta tctagtgaaa acgtatcact
    15601 atatttttct tgaatgtctt taaagacttt gtgaggtatc tctggaaagt ctttaatata
    15661 tagctcataa cctgaatcta taaggtatga agctatgtat tcttccaaag ttccccattt
    15721 aatccagtct gcactagtgt ttccaatatt tgcaattgtt aaaagcctat ttttattggg
    15781 taaagacacg cctctaagcc aattattaac agaacttatt ggtgtgtcgc caattaaatc
    15841 accgaattgt tctaatgtca gacctttgga ttcaataatt tttctaatac gtttactagt
    15901 taacgataga ttaggtttca tagctaagcc tcctcgtgag taaagtaatc tttcaatatt
    15961 ttttgtgaat caacccattt tatcgagaag tgatagttga caaatagcat tgagagatat
    16021 ttctcgctta tctggatcat caatttttga aatcacatta agataaccgg cgaagctttc
    16081 aattattcta ttgacttcct caattgacag acgttccaaa gcatccaatg ctacttcaga
    16141 tagaaaatac attgattctg ctacgcttga atcgacaccc gtcataagat aaagttcaga
    16201 aactccgcca atttctgcaa tctttttaat tctttctgag ttaggaaggt ttttaccatt
    16261 ttcccagttg cttataacag ctttatcagc tgtaggagag aatagtttgc cgaattcttc
    16321 taatgtaata ttctcttttt ttcttatttt ccttatacgt tgtccaatca ttttaatatt
    16381 tttgttgtca tcagtcagtc ctaaatctgg tttgacttct atgtctcgat aatcttcaaa
    16441 atcttttgag taatattttg taaatatatt ttttattata ggattcaata actcatagtc
    16501 tttatttagc gaaaacgtat tactatatct ttcttgaatg tcattaaaga ctttgtgagg
    16561 tatctctggg aagtctttaa tatatagttc ataccctgaa tctttaaggt atgaagctat
    16621 gtattcttcc aaagttcccc atttaatcca gtcgatagtt ttgttactta attcagcaat
    16681 tttaattaat ctttctttgt tgggaaggga gaatcctcgt tcccaattgt taatatttcc
    16741 tttttgagca tttccaatta aatctgcaaa ttgttccata gtcattccaa aattagaacg
    16801 aattgattta attcttttac ctgtttcaac aggatttggt ttcatacaat cacctctctt
    16861 atggaatttg gtttacttca aattcttttg agtaatattt tgtaaatata ttttttatta
    16921 tagaatccaa taattcatag tctttatcta acgaaaacgt atcactatat ttttcttgaa
    16981 tgtctt
//
LOCUS       DACDLM010000060        16626 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.061, whole genome shotgun sequence.
ACCESSION   DACDLM010000060 DACDLM010000000
VERSION     DACDLM010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16626
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.061"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..160)
                     /locus_tag="IV356_002090"
     CDS             complement(<1..160)
                     /locus_tag="IV356_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAP9015756.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINR"
     gene            complement(162..359)
                     /locus_tag="IV356_002091"
     CDS             complement(162..359)
                     /locus_tag="IV356_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterocin"
                     /protein_id="HAP9015757.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(753..2480)
                     /locus_tag="IV356_002092"
     CDS             complement(753..2480)
                     /locus_tag="IV356_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP9015758.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2473..3666)
                     /locus_tag="IV356_002093"
     CDS             complement(2473..3666)
                     /locus_tag="IV356_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HAP9015759.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(3853..4497)
                     /locus_tag="IV356_002094"
     CDS             complement(3853..4497)
                     /locus_tag="IV356_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP9015760.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4591..4725)
                     /locus_tag="IV356_002095"
     CDS             complement(4591..4725)
                     /locus_tag="IV356_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HAP9015761.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(4727..6859)
                     /gene="feoB"
                     /locus_tag="IV356_002096"
     CDS             complement(4727..6859)
                     /gene="feoB"
                     /locus_tag="IV356_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HAP9015762.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(6856..7329)
                     /locus_tag="IV356_002097"
     CDS             complement(6856..7329)
                     /locus_tag="IV356_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HAP9015763.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            7730..7954
                     /gene="nrdH"
                     /locus_tag="IV356_002098"
     CDS             7730..7954
                     /gene="nrdH"
                     /locus_tag="IV356_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HAP9015764.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8113..10272
                     /gene="nrdE"
                     /locus_tag="IV356_002099"
     CDS             8113..10272
                     /gene="nrdE"
                     /locus_tag="IV356_002099"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HAP9015765.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10322..11287
                     /gene="nrdF"
                     /locus_tag="IV356_002100"
     CDS             10322..11287
                     /gene="nrdF"
                     /locus_tag="IV356_002100"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HAP9015766.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11376..12515)
                     /locus_tag="IV356_002101"
     CDS             complement(11376..12515)
                     /locus_tag="IV356_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP9015767.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(12824..13537)
                     /locus_tag="IV356_002102"
     CDS             complement(12824..13537)
                     /locus_tag="IV356_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HAP9015768.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(13791..14492)
                     /gene="nagB"
                     /locus_tag="IV356_002103"
     CDS             complement(13791..14492)
                     /gene="nagB"
                     /locus_tag="IV356_002103"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HAP9015769.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            14726..16258
                     /locus_tag="IV356_002104"
     CDS             14726..16258
                     /locus_tag="IV356_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP9015770.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16449..>16626)
                     /locus_tag="IV356_002105"
     CDS             complement(16449..>16626)
                     /locus_tag="IV356_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP9015771.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5159 a         3424 c         2875 g         5168 t
ORIGIN      
        1 atctatttat taaaggactg ggatctaatt catatttttg tttttctaat tttaaatata
       61 ccttttgtaa aacctcaaga atatcagaat atttaggatc tttacttata gatatatcat
      121 tatataattc atgaacaatt tgcttagcat tttttttcat tttagcactt ccctggaatt
      181 gctccaccta aaaaaccacc tatagacatt cctgcaatac aagtagttgc cttggcccaa
      241 tcgaccgtac atttattttt agtgcaatac actccatttc cataatattt tccactatga
      301 gtggtacccc catagataag ttgtgtctct ttaatagaca aaatttttaa atgtttcata
      361 atctaatcac ccctaaatta atgtttttag actattattc taacattcat taaatttcaa
      421 aaaacaattc cttcttgaaa cgtagcaaaa taattcctga ataagaattt aatcactttt
      481 aagtatataa actatgtata ttctttaata ttttttgaga atgcacttcg tacataataa
      541 actttaatca cattagtctt tcatacctac gatcgatctc tttgactcgc acccataaat
      601 tcataatagt ttgtcggcgt ctttgaacgt ttcgaagatg agctacgcat tctctttttt
      661 tatagacaaa aaagatagag acgaacatgg agcttccaaa tttggatatt tgatccaatt
      721 ttggaagctc catttatttc gtgtctgtct ttttattttt tccagctttc gactaattct
      781 tggttctctt tgatccagtc ttttgctgct tgctgtggat cttttccatt gttgatttcc
      841 aacataactt tttccatatc tttttctgac caatggaaat tgtctaatac tttgtaagct
      901 tctggctggt cttctttcaa tccttttcga accatcgtat ggatctgctc ttcgcttccc
      961 attccgtttt caggatcttc taagtatttc agatcatatt tggcaaacat ccaatgaggt
     1021 gtccatcctg taactacaat tggttcgtgt tttttgatcg cttgacctag tgcaacggtc
     1081 attgctcctg aagaagatgt ctctactttc cagtctttca agttgtcata tttttggatc
     1141 gtgttttcag cagccgtaac tacaccagct cctggctcga ttcctatgat tttcttacct
     1201 gcctgatcgg ttaactcatc gatcgaattt acatccatgt aggctggcac tgctaaacca
     1261 acttttgctc ctgtcaaatt ggcacctagg tcttcgactt gatctttata ttgtgcatat
     1321 tgtgaaccat gagttttagg tagccaagct gaaaccatgg catctgactc gccatttgaa
     1381 acagatttcc acatgattga attatctaat ggcgtcatcg ttacatcata gcccatttgt
     1441 ttcaatactt caccgactac atttgttgaa gcaacttctg tatcccattc aacataagat
     1501 aagttgatac gttttgtttc tttggcagat gaaaaactcc ctataccaat cgcacctaag
     1561 atcactacta ctacagcacc aatgatcagt ccttgacgtt ttttactttt ctgtgttgtt
     1621 gctcctgcag cttttttatt gtttggctgg ttcaaatgct gtgtaaaacg gtcaatgatg
     1681 attgctaaga taactaatgc aaccccgttg acaaatccat tcccgacttg tgctctttgc
     1741 aatgctgata atacgccgcg tcctaagccg ggtgcaccga tcatagaggc aataacgacc
     1801 attgaaagtg acagcattgt tgtttgattg atccctgcca tgatcgtact tttagctaaa
     1861 ggcaattcta gtttgaatag tttttgacga cttgtgctcc cgaatgaatc agaagcttct
     1921 actaattctt taggaacttg tcgaatccct aaattcgtaa aacgaacggt tggtggcaga
     1981 gcaaagatga ctgaggcaaa tacccctgga accatcccga taccgaaaaa tgcaactgct
     2041 ggaatcaaat aaacgaatcc tggcattgtc tgcataaagt caaggatcgg tttgataata
     2101 ctttgggctt tactgctttt tgccatcaag atccctaatg gtaccccaat gatgatcgag
     2161 atcacactag ataaaagaac aagtgtgaca gtattcatca aatcattcca tagaccttgg
     2221 ttataaataa accatagacc gattaatgtg aacaacgtaa gtcctggacg tttcttagaa
     2281 ataaagaaag ctgctaccgt caataacaag ataaacaaag gagctggaat cactaacagt
     2341 aaatttgtaa ttcccgacat cactgcctgt ccaatcgttt gtaaaaatga aaataggcca
     2401 gaaaaagttg tcgtaaacca ttctgtgata ttttctaccc agtttgccac tggtaattga
     2461 tagttcaata gattattcat gttcactcac ctcgcttgtt tctgctaatg cttcaatcac
     2521 actacctcgg atgacgacac cttttaattt tccatcctct acaactgcaa gtggagtcgg
     2581 tgagtcataa ataatattga aaatatcact taccaccatg tctttcccaa tcaccgtcac
     2641 attttcatct aggaagtcga tcaatggacg tttttgcttc ctagcttcta acgcttgatc
     2701 tgcagtgatg atccctttca ggtgtctctt tctgtcaaca gccatcagca tgctgacttc
     2761 ttcattacgc atccttgtca atgcaacgtt tggtccatca gattcgatat tcgtcgtcaa
     2821 tgcaggtacc atgatgtttt gagccgtaag cactttggaa cgatcgactt cttccacaaa
     2881 ttcacgtaca taatcatttg ctggattggt caatatttct tcacctgttc cgatctgcat
     2941 gatttcgccg tctttcatca aggcgattct gtccccaatc cgtaaagctt cattcaaatc
     3001 atgggtaatg aaaataatcg ttttttgaac attggcttgc aggtccagta attcgtcttg
     3061 catttctcgc cggatcagcg gatcaagagc cgagaacgct tcgtccatca gcaagatctc
     3121 aggatcattt gctaaagctc tggctaggcc aacccgttgt tgcatcccac cagataactg
     3181 actaggatat tggtctttaa atgaaagcaa actagaattt tctaatgctt tttctgcttt
     3241 ttcttgtcgt tcttctttag gtacaccacg gacttctaac ccgtattctg tattttccaa
     3301 gatcgttcga tgtggaaaca gaccgaagtt ttggaaaacc atattgattt tatgacgacg
     3361 gacttctcgc aattcttctt tgcttaactt cgatacatct tctccatcaa tatagatact
     3421 gcccgaagtt ggctcaatca gacgattcaa tagacggatc aatgtggatt tcccactccc
     3481 ggaaagcccc atgatcacga agatttctcc ttcttttacg tcaaaattca cgtcatacac
     3541 accaaccgtt gcaccggttt tctttaaaat ctccgttttc ggctggtgat cattcatcat
     3601 atctaaagcg gcttgtgtct ttttaccaaa tatctttgtt aaatgtttta cttctacttt
     3661 taccaaacaa attctccttt tttatgtaaa ttcatttttc tttctgaaaa aagtgaccac
     3721 actatgttaa catcatgtag tcactttgtc aaaaatgaaa gaaatttgct tgtccaaact
     3781 gaaaaaaact tggctaaatc tttgtaaata aaaggtttag ccaagttaat atttttttaa
     3841 tatttcacac aatcattctg caagctgatg ctccgggtaa aaaaagtttg tcatacgctg
     3901 tagtgtatat tcatttccaa taaaatgaac gatgtcccct gccgtaaatt tagcataggg
     3961 gccaggtgaa acaagcagtt cttcattatg agaaattgcg ataactgtgg cgccagtcgc
     4021 ctgccagata ttcaactcgc taattgaacg gtccagatgc attgcttttt ctgataaaga
     4081 taattcaaac ggaagtaaag gattcatctt atgtattcgc ttcgtttgat tgaccagctg
     4141 atccaataat tgagaaaaat gattcagctc atcttgttgc ttctccacac ttgccatgat
     4201 ttctgctttt gtatcttgga tggattgtac atcttgatat tgcaatagga aatcttttgc
     4261 tttttccttc gaagcaacaa atgccccact tccatgccgt acttccatga ttccaagatc
     4321 taccagcaca ttgatagcct tgcgggtagt ctcaggagaa gcattgtacg tactggcaag
     4381 tgttgagcgg gcatggatct tctcacccac tttatatcgg ttttcaacga tacgttcggc
     4441 taaatcaaca gcaatctgct ggtagcgcgg gcggacgatt tttttctttc cagacatttt
     4501 ctttcctctt tcttttttta ctttccctca tcttactatg ctctagcaaa ataagcaaaa
     4561 aaggggagaa tagcctcttg caacgactga tcatcgcttg atctgttcct tttttactgg
     4621 gcaagctgtt tgacagtcat cacaattctt accggatttt aaacgagtat agacaattgc
     4681 gcctgcactt ccaaagatta acacacttaa taagaatgtc gccatcctat tcctctcctt
     4741 ctaatgacaa tatagtataa aactggttct tggattttgg ctgacggaac aaaacataaa
     4801 cgagtcctat catcagtaaa atagcaagat acgtccctaa cgctacctgt ccaccctcca
     4861 ataagtgtcc caactgataa atcacaaaac taactaaata agctaaaccg cattgatagc
     4921 ctatggcgat ccaagtccat ttcttggcat tcatttcccg atggatagcc ccaattgccg
     4981 caaaacaagg cgcacaaagt aaattgaagg ctaacaatga ataagctgct gcgggagtat
     5041 atgtgtgttg tagcacttgc cagatttctc tgccattttc ggatacttcc gcatgaccaa
     5101 acaaaatacc aaatgtgcca ataatatttt ctttagcgac caatcctgta atcgctgcga
     5161 ctgttccttg ccagtttccc caaccaagcg gctgaaaaac aactgccagg attcgcccga
     5221 aaaaggctaa gatactttgg tcttcagaaa caggttgagc ataaaaatta taagaagagc
     5281 tgaaccagat cacgatacta gaaacaaaga taatcgttcc tgctttttta acaaaagact
     5341 tgctgcggtc ataggtttgt cttaggaccg ctgaccattg aggaaaatga tatgcgggca
     5401 attccatgat aaaaggagct gtatctccag caaacaaacg tgtttttttc aagctgattc
     5461 cagagaaaat aattgcagtc ataccaagaa aataggcaga aggagctacc caagattgat
     5521 gaggaaaaaa ggcccctgct actaaggcaa taatcggcaa ctttgcagaa caaggcatga
     5581 aggttgtgac catgatcgtc aaacgacgat cttgctcgtt ttcaatcgtg cgactggcca
     5641 tgacgcctgg cactccacat cctgtagcaa tcagcatagg aatgaaggat tttcctgaaa
     5701 gaccgaattt cctgaaaagt cgatccatga caaaagcgat cctcgccata tatccgcagt
     5761 cttccagaaa gctcaagcat aaaaacaata taatcaattg cggtagaaat cctaacactg
     5821 ctcccacgcc tgcgatgatg ccgttcaaga tcagctcctg catccatccc gctacttgcc
     5881 attcagctaa caatctgcca acatgttctg gtaaccatgt accaaacaat gtgtcattga
     5941 tccaatctgt ccccattgtt cctactgttt gaatagccag ataatagatc agccacatca
     6001 caaatgcgaa gatcggcaag gctaaccaac gattcgttgc aatctgatcg attttgtcac
     6061 tcatcgataa ttggaaagaa tcatttgaca caacacagag tgtacatagt tgggtaataa
     6121 attcataacg ttcattgacc agaatcgtct cactatcgtc gtccaatagt ttctctgtta
     6181 actggatcag ttgctcgatc tctttttgct gagaaactgc tatctcgtaa tcctctctta
     6241 ccttctgatc tcgttcaaaa tatttcattg cataccagcg tttcttgccg ctttgttctc
     6301 ctagtacatc ttcaatttca tgtaaagctg cttctaaacg tggatcatat gtacagggaa
     6361 caggaataga aggccgcttt tttgcagact cctgaatctt ttcgattagt ttttcgattc
     6421 cttgcttttt caatacgctg attggtaaaa ctggtacacc aagaccatag gaaagctttt
     6481 ctagattgat tttttttcct tcttttttga tgacatccat catattcaga ccaatgatca
     6541 taggaatgtc taaatccaat aactgcgtag ttaaataaag atttcgttct aaattggtag
     6601 catcaataat gttgatgatc agttcaggct gttcctgaac caaataatct cttgcaatca
     6661 cttcttctgg tgtataagga gacaaagaat agatgccggg taggtcctga atatgaatgt
     6721 tcggattttt tttcaacgat ccttcttttt tttctactgt tacgcccggc caattcccta
     6781 catattgatt cgaaccagtc aagagattga acaagctagt tttcccgctg tttggatttc
     6841 cgactaacgc gatattcatt ctttttcctc cctttgtatc aagattagtt cggcctctga
     6901 ctttcgtaac gtcagttcat accctcgcac tgtcagttcg attggatctc ccagaggggc
     6961 tagttttcgg ataactattt ttacatttcg cgtcaatccc atatccatta accgtcgctt
     7021 cactgcgcct tgtccgtgga ttgctacgac gatcccagtc tctcctgctt ttaattgatc
     7081 aagagaagtc cagctttcag aggaagcagt ctttttattg acaaagattt gacctagtat
     7141 ttcccgactt actgccactc gatgactttt taccagtaaa atggcattgt tgcctgataa
     7201 attgacgacg acgattttac ttccggcaac gatcccgata ttttgcaaat ggcgttttgt
     7261 tttttcttct gtttcgattc gttcgacttg ataaacgaaa ttctgctttg cctgcgctaa
     7321 ggtctgcata ttgattcctc tcttgtgaaa taaatcatgt attaaaatca ttcattatat
     7381 gttctaattt tcttacgtgt tacgcaaata aatgagaatc attctcacat agaatactct
     7441 cggtaattga gaatgtcaat tatacttgtg atattatgag cgaatcttta gtattgatag
     7501 ataaaaatga gaaaaaaata tttcttcata gttttccaca attttttctc tattaaattt
     7561 gctattttcc cacacgatac ttgttttcag ctcttttttc aaaaacacaa aacttagtat
     7621 tccacagttt ccacaacaca atatgtagtg tttgttgttt gactttttta ctaagagttt
     7681 tatactatct attatagata ataagaatgt gttagaggag gcactcacca tgaacgtaaa
     7741 aatcttttct aaaaataatt gtatgcaatg taagatggtc aaacggtttt taacagaaaa
     7801 tcaaattgct tttgaagaag tcaatatcga tgaacagcct gaagcagtag actggttgaa
     7861 agcacaagga ttccaaagtg ttcctgtcat tacttctgat gcagaaacag ttatcggatt
     7921 ccgtcctgat cagttgcgta aacttgccag ctaacatgac taaaagaatc aaaacgtgat
     7981 acatggattt gaagggcttg agacagcacc agtttttgtc gcaaacttcc aaatcctttt
     8041 ttaaagctta aaaacaatgc aatgatttgc aatcaagcat catcaaatac gaaatgaagg
     8101 ttgggcgtac gtatgagtct taaaaattta caagatgtca gttatttcaa gctgaataat
     8161 gaaatcaatc ggccagtcaa tggtcaaatc cctttgaata aggataaaga agctttagtt
     8221 gccttttttg aggaaaatgt caaaccaaat acgatgactt ttccatctat tatggaaaaa
     8281 atcaattact tgatcgatca agaatatata gaagcagaat tcattcaatt gtattcacca
     8341 tcatttattg aaaagctata tcaatttttg gacgagcaac atttttcttt caaatctttt
     8401 atggctgctt acaaatttta ttctcaatat gcgttgaaaa ccaacgacgg ttccgcttat
     8461 ctggaaactt atgaagatcg agtagccttc aatgcgcttt actttgcgaa cggggatgaa
     8521 gaattagcac ttgctcttgc agacgaaatg atccatcaac gatatcagcc agctacacct
     8581 tctttcttga atgctggacg taaacgtcgg ggcgaattgg tgtcttgttt cttgactcaa
     8641 gtcactgacg atatgaactc tatcgggcgc tcaatcaact ctgctttgca attgtcccgt
     8701 attggtggcg gcgtagggat tactttatca aatcttcgtg aagccggcgc tcctatcaaa
     8761 ggatatgagg gtgctgcaag tggtgtcgtt ccagtcatga aattattcga agatagtttc
     8821 agctattcta atcaattagg tcagcgtcaa ggagctggcg tggtttattt gaacgttttc
     8881 catccagaca ttattgcttt cctttcagca aaaaaagaaa atgcagatga aaagattcgc
     8941 gtaaaaactc tttctcttgg cgtgatcgta cctgataaat tttatgaatt gacacgtaaa
     9001 aacgaagata tgtatttatt tagtccatat agtgtcgaaa aagaatatgg tgtcccattc
     9061 tcttatgtaa atattacagc tgagtatgat catctagttg caaatccaaa cattcgcaaa
     9121 caaaaaatca aagcgcgtga tcttgaaaat gaaatctcaa aattacaaca agaatctggc
     9181 tatccttacg taatcaatat tgatacagcg aaccgcgaga atccaatcga tggcaagatc
     9241 atcatgagta atttatgttc agagatttta caagttcaaa cgccttctgt gattaacggc
     9301 aaacaggaat atgaagtatt aggaacagat atctcatgta acttaggctc gacaaatatc
     9361 gtgaatttga tgcaaagccc taactttggt caatctgtgc gtacgatgac tcgtgcattg
     9421 acatttatta cagatgcatc tgatatcgat gtcgtaccac cgatccaaaa cggaaataag
     9481 ctgaatcata cgattggatt aggtgccatg ggcttacaca cttatcttgc aaaagaacaa
     9541 atggaatatg gctcagagga ttcattagac tttacaaata tttacttcat gctgttgaat
     9601 tattggacac ttgttgaaag caacaatatc gctcgtgaaa gaaaacaagt tttccataat
     9661 tttgaaaaat cagcttatgc tgacggcact tatttcgaaa aatacgtaac tggagaattc
     9721 cagccaaaat cagaaaaagt caaagcattg tttgaaggca tttttatccc aactgctgaa
     9781 gattggaatg ctttgaaaca agcagtaatg aaagatggac tgtatcatca aaatcgcttg
     9841 gcagtagcac caaatggctc aatttcatat atcaacgata cgagtgcaag tattcatcct
     9901 atcactcgca tgatcgaaga acgccaagag aagaaaatcg gtaaaattta ttacccagcg
     9961 ccttatctat ccaatgagac gattccgtat tacacttctg cttatgatat ggacatgcgt
    10021 aaagtaatcg atgtttatgc aacggcacaa caacacgtcg atcaaggcat gagtttgact
    10081 ttattcatgc gttctgaaat cccagaaggc atttatgaat ggaagacaac aacgaagcaa
    10141 acgacacgtg atttgaatat tttaagacat tacgctttcc acaaaggaat caaatccatt
    10201 tattacgtac gtacctttac tgatgatgca gaagaaatcg gaagcaatca atgtgaaagc
    10261 tgcgtgatct aatatcatag atagattcgc ttattcatat tttaattaaa ggagcattct
    10321 catgtcagaa acatattatg aagcaataaa ctggaatgaa attgaagata tcattgataa
    10381 atccacttgg gagaagctga cagagcaatt ttggctagat acacgtatcc cactttcaaa
    10441 tgacctagat gattggcgta cattgtctca attggaaaaa gatacagtag gacatgtatt
    10501 tggcggtttg acactgctag atactgtcca atctgaaagt ggcatggatc agttgcgtaa
    10561 agatgtccgc actccccatg aagaagccgt tttgaacaat attcaattca tggaatccgt
    10621 tcatgccaaa agttattctt ctatttttag tacactgaat acgaaaaaag aaatcgaaga
    10681 aatttttgac tggacaaata cgaatcctta tctgcaaaaa aaagctgagc gtatcaatga
    10741 aatctacaaa cacggtacac cgctagaaaa gaaaattgcc agcgtctttt tagaaacatt
    10801 cttgttctat tcaggttttt atactcctct ttattattta ggaaacaaca aattggctaa
    10861 cgtagcagag atcatcaaac taatcatccg agatgaatct gtacatggaa cctacatcgg
    10921 ttacaaattc caattaggat tcaacgagtt acctgaagca gaacaagaaa cgttaaaaga
    10981 ctggatgtac aatcttcttt atgagcttta cgaaaacgaa gaacgttata cagaagaatt
    11041 atacgatcca atcggctgga cagaagaagt caagacattc ctacgctata atgccaacaa
    11101 agcattgatg aacctaggga tggatccact ctttccagat actgccaatg atgtcaaccc
    11161 aatcgtaatg aacgggattt caacaggcac aagcaaccat gacttcttct cacaagtcgg
    11221 aaacggctat ttgttaggtc atgtagaagc gatgaaagac gacgattatt tgattggatt
    11281 ggaataagga tttattttaa ttcaaaaatt tttcgaaaaa taaaaagagt ttagcgtaca
    11341 gatattttaa atgtacactg aactcttttt tatgcttatt cacttgtttc ttccagcact
    11401 tttggactgt ctaacttttc cgaaacatgt tccattcttc tcaataaata gattttccgg
    11461 atatttaata ttatcgtctt aatcactgca tagacaggta tgcaaatcag catgcctaat
    11521 attcctgcga cacttcctgc tccaatcaat accaagatga tcgtcaaagg atggatattc
    11581 attgatttcc caaataacaa cggcttgatc aaatttccat ctaattgttg gatcactaaa
    11641 atcgacaacg ccatatacaa agcttgaaat ggagagataa acaaaccgac aatgattgct
    11701 ggtaccgctc caataaaagg gccgacatac gggataatat tcgtgattcc gcaaatgacc
    11761 gcaagcaaca agctataagg ctgatcgaat attctcattg ccaaaaagct cattacacca
    11821 ataatcaaag catctaagat cgtactgctg atataggcag ataatgtttc gtttaattct
    11881 tttaccgttt ggcgtaactc tttacgaatc gctttcggaa agaagtgaga caacgcatca
    11941 ataaatttgt gcccatcctt gaacataaat agcaaaataa atggaacggt aaataacaaa
    12001 ataaaaaatt gcatcataaa tgaaatgatt tttgagacac ttgcagataa actgactaat
    12061 atgatattga acaaattact aagagataaa tttgctgatg ctaattgttc ttccaaattg
    12121 aaatttttaa actcttcccg ctgcgccaat tcatttaacc atttgcttgt ttcatctgca
    12181 tacattggca agctctgggt caattgaatt gtctgttcca ttaactgagg cactacattc
    12241 atgacagtta aaacaactaa aatgattacg accaaaaacg tcaataaaaa accgaacact
    12301 ctcgggatcc gatgcttttc gagaaaaaca acgattggat cgaacatata atagataaaa
    12361 ccagcaacaa gcaatggtaa aaaaattgcc gaaagcattt tcaatattgg actaaaaata
    12421 ttcggcattt gtaaaataaa gtacacgccg atgatcgtga gtactagctc cactgtccag
    12481 aaaaataatt ttgattgttt aaaacgtgat tgcatacatc tcctccaagg tcctttgata
    12541 cttctattct atcatttaac aaagagttac gcgctgagat tttcatttgc ttaaaaaaaa
    12601 caaaaaaaat aaacatattt taatgagtag acgagtactt aaacaaaaac acggtttgga
    12661 gtagtgacaa aaattatact gcagtccctt tttccaaata aacggtgttc aaaagcttgc
    12721 atcttcgtaa taagcccagc caaacgaaaa atataaggaa ctatttttat ttggctgggc
    12781 ttattacttg atgtaggaca tctattttac aacctcagat catttattgc gcaatactga
    12841 ctaaatgcaa ctttgtgata tttttgtgta cggacaactc ctcgatcaca tcggcataag
    12901 tgagcccttt tggaagatca atcgtataga tatttttgta cactcggtag tcatcaacga
    12961 attttacgtc aaaattcaca tcttcgatta cgatattttt ctcttcaaaa taatcggtaa
    13021 gaaaatcttt ggtttctttt ctatggataa attggatttc taacttttta gtcgtaggta
    13081 catggatcac gcgtttcact actgtgagtg caatagcaat cccgataaaa ctgatgatcg
    13141 caatggaata gtaacccatg ccgatggcga tccctaatcc agcaattgcc cataaagaag
    13201 cggcagtcgt aagtcccgtc accgattgtt tcgtgacgat gatcgttccc gcgcctaaga
    13261 aaccgacacc actcaccact tgagcaatca gccttgcttc atctgaacga atcgttccag
    13321 caagctgtgg atactctaaa gcatctctta atgcaccact agcgatctca acttggatca
    13381 atgcaatgat acatgctccc atacaaacta aaatatgcgt acgcatacct gctggacgat
    13441 ttttatattg tcgttcaaaa ccgattgctc cgccaaatag catagcgatc cctaaacgta
    13501 aaataatctc tggaattgtc aataccatat cattcatcta aacaccctcc agtccaatat
    13561 atcatgtctg aaaggagcag acaaaaaaag tgcaattttt acctcttacg aaaaaaggac
    13621 tgtgacaaaa tttttgtcat agtccttttt atgaataaac ggtgttcaat cagctgaccc
    13681 tcggtattac tcaacaaacg gcaaaatatg gggagctatt tttcctttgt cttctctaat
    13741 actcaggtca aaacgctgat ttcacaacct ctttagccta ctattgaaaa ttacaactta
    13801 cttgctgctt cttcatcgat gatcacaaca acattgtcgt gattttgcaa tacacttgct
    13861 ggcaaatgat tcgttacagg tccttcaatc atccctttga ttgcatcagc tttgctttcg
    13921 ccaaatgcca tcaagacgat ttctttactt ttcataattg aaccgattcc cattgaaaca
    13981 gcttttgttg gtacatcttc tgctttatcg aagaatcgtt tgtttgcatt gattgttgat
    14041 tctgttaagt caactactga agtcgttccg tcaaatgaag caccaggttc attgaaaccg
    14101 atatgtccat tttgcccgat tcctaagatt tggatatcga ttggatgtgc atcgatgatt
    14161 tgatcatact ttttgcatgc tgcttccaga tcttctgctt ttccatctgg tacaaacgtt
    14221 tctttgaatg gttttttatc aaataattgg acatccatga aatgacggta gctttgttca
    14281 tctgaaccgc ctagtccaac gtactcatct aagtttacag aagtcatttc actgaaatcc
    14341 aaatcgcttg aagtcatttc tttatataaa gtaactggtg tgcttcctgt tgccaatcct
    14401 aatacttttg cacctttgtt cataccttct ttgatgattt caaatgcttt ttttccgcct
    14461 tcttcagcgt tttttacacg aatgatttcc atagtgattg ctcctttata ttttggtata
    14521 gcccaattat agcattcttt ttttcttttt acaataatta gtatagacca aattgcattt
    14581 ttttcatttt cttgacaata aataggaatc cgtgttaggt ttcataagat ggttcaatca
    14641 aacaatccat gttgcatgaa aaccaagcaa gtgattcact gtggacgctt tatgtctgca
    14701 gtttttttat gaaaaaggag ttattatgag tatactgaca ttaaacaaca ttacccagca
    14761 atttggcgac aaaatcctct atgaaggtgt cgatctgcaa ttaaatgctg gcgaacatct
    14821 tgggctgatt ggacaaaacg gagccggtaa aagtacattg attaaaatca tcactggtga
    14881 gatcttacca gatgacggac agatccattg gcaaaaaaat attcacaaag gttacctcga
    14941 tcaatatgtg gaagtcgatg aaacattaac aatcgaagaa tttctaaaaa ctgcgtacgc
    15001 aaaagaatac gaaaaggaag aaaaaattgc ttttctttac caaacatata gcgagacctt
    15061 cgatgattcc ttgctggaaa aagctgggaa actccaaacg gaattagacc aaggagtgtt
    15121 ttatcaaatc gacaccttag ttgctgagat gagcagcggg ttggggatcg atgtcttagg
    15181 tttagattca ctgttgaaaa atctaagtgg tggacaacgt tcaaaggtga ttttagcaaa
    15241 actactttta gaaaacccag atgttctgat cttagatgaa ccaaccaatc acttagatga
    15301 tcagcatatc caatggctga cgcagtttct tcaggatttt gacggtgcgt atatcgtgat
    15361 ttcccatgac caagaatttc ttgatcagat caccacccat atcgcagaca tcgagtttgg
    15421 aaagattact aagtatactg gccatctaaa acaagcattg aaacaaaagg aacaaaatcg
    15481 cgaaagctat ttgcgccaat atcatgctca acaaaaacaa atcgaaaaga ccgaagctta
    15541 tattcgaaaa tacaaagccg gttcccgatc aacgatggca aaaagccgac aaaaacaatt
    15601 agataaaatc gaacggctga cgcctccagc ttcagcaagt aaagctgtct ttgattttcc
    15661 attctcgcct attgtcacga cattagcagt ggaaacaact gatttagtca tcggatatga
    15721 tcgaccgcta cttgcaccca tcaatttgac catccgcttt ggtgaaaata ttgccattcg
    15781 aggcttcaac gggattggaa aatctacttt attaaaaaca ctgatcggtg agattgaaaa
    15841 aataagtggc gatttccact tcccagataa cacaaaaatc aattactttt cacaagatct
    15901 gtactgggaa aatccattag aaacaccact acaatattta agcagtcaat ttccaaaagc
    15961 gactatcaaa gaattacgtc gccaactagc taaagcaggg ttagttaatc aattagcaag
    16021 tgaacctctc actacattaa gtggtgggga acaaactaag gtgaaacttg cacagttgac
    16081 aatgaaccaa ggtaatttac tgattctcga tgaaccgacg aaccatatcg atcaagaaac
    16141 gaaagaaagc ttacaagacg ggatacagaa atttccagga acagtaatca tcgtctctca
    16201 tgaacaagaa ttttatcaag atcttgtgca acgagtcatt gagattgaac caaaataaac
    16261 gtttgattga atagttgaaa aaaaggagct gtgacaaaag ttttgtcaca actccttctt
    16321 ctgaataaat ggtggccaat tagctgacct tcggtattag ctcaaaaaac ggcaaaatat
    16381 gaggagctat ttttatttgg ctattcttat tacttgatgc agaacagctt ttcacaacct
    16441 cttttcgtct attttttatt ttcgagattt ctctttcctt taaaaacaac tgtttgaaag
    16501 aagaacgcac atccttgaaa aacaagcccg ctaaccgtta cacctaacca gccatactgc
    16561 tgccacattg tcgtccctag caatgaacca gccgcacctc caataaagta cataaacata
    16621 aataca
//
LOCUS       DACDLM010000061        16527 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.062, whole genome shotgun sequence.
ACCESSION   DACDLM010000061 DACDLM010000000
VERSION     DACDLM010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16527
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.062"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(141..416)
                     /locus_tag="IV356_002106"
     CDS             complement(141..416)
                     /locus_tag="IV356_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008214712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HAP9015772.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(659..1969)
                     /locus_tag="IV356_002107"
     CDS             complement(659..1969)
                     /locus_tag="IV356_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HAP9015773.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(2151..3380)
                     /gene="rpsA"
                     /locus_tag="IV356_002108"
     CDS             complement(2151..3380)
                     /gene="rpsA"
                     /locus_tag="IV356_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HAP9015774.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(3515..4195)
                     /locus_tag="IV356_002109"
     CDS             complement(3515..4195)
                     /locus_tag="IV356_002109"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HAP9015775.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVPFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(4244..4879)
                     /locus_tag="IV356_002110"
     CDS             complement(4244..4879)
                     /locus_tag="IV356_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP9015776.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(4945..6348)
                     /locus_tag="IV356_002111"
     CDS             complement(4945..6348)
                     /locus_tag="IV356_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HAP9015777.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATKQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(6335..7366)
                     /locus_tag="IV356_002112"
     CDS             complement(6335..7366)
                     /locus_tag="IV356_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015778.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESEVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            7397..7618
                     /locus_tag="IV356_002113"
     CDS             7397..7618
                     /locus_tag="IV356_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HAP9015779.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(7783..8520)
                     /locus_tag="IV356_002114"
     CDS             complement(7783..8520)
                     /locus_tag="IV356_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HAP9015780.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(8673..10013)
                     /locus_tag="IV356_002115"
     CDS             complement(8673..10013)
                     /locus_tag="IV356_002115"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HAP9015781.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(10250..11773)
                     /locus_tag="IV356_002116"
     CDS             complement(10250..11773)
                     /locus_tag="IV356_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HAP9015782.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(12151..12762)
                     /locus_tag="IV356_002117"
     CDS             complement(12151..12762)
                     /locus_tag="IV356_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP9015783.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(12885..13010)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(13092..13808)
                     /locus_tag="IV356_002118"
     CDS             complement(13092..13808)
                     /locus_tag="IV356_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAP9015784.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(13814..14383)
                     /gene="scpB"
                     /locus_tag="IV356_002119"
     CDS             complement(13814..14383)
                     /gene="scpB"
                     /locus_tag="IV356_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HAP9015785.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(14367..15164)
                     /locus_tag="IV356_002120"
     CDS             complement(14367..15164)
                     /locus_tag="IV356_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HAP9015786.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFGTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(15134..15505)
                     /locus_tag="IV356_002121"
     CDS             complement(15134..15505)
                     /locus_tag="IV356_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAP9015787.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(15524..16411)
                     /gene="xerD"
                     /locus_tag="IV356_002122"
     CDS             complement(15524..16411)
                     /gene="xerD"
                     /locus_tag="IV356_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HAP9015788.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
BASE COUNT         4644 a         3577 c         2799 g         5507 t
ORIGIN      
        1 aaaaattaaa taaaatacat gtgttttcta tgtatgacat acggattcgg aatctctgtc
       61 tcttatttat tccttttctg ctaggaaata aaaagaaaag cacttgtagc cctagagcca
      121 caagcgcttt ttcaactgtc ttatttaaca gcgtctttta atgctttacc tggtttgaat
      181 gcaggtactt tgctagctgg aatttcgatt tcttcaccag tttgtgggtt acgacctttg
      241 cgagctgcgc gttcgcgaac ttcaaagtta ccaaaaccga ttaattgaac tttttcgccg
      301 ttagctaaag catcttgaat agttgaaaat acagcatcta ctgctgcagt tgcatctttt
      361 ttagttaaat cagtagctga agcaactttt tcgattaatt ctgctttgtt tgccatggat
      421 agattcacct cctccacaag agatatgata gaaatatcat ttagttaaaa ctttctgagt
      481 ggtccagaag tttaaaaaga aatattgatt aacttcaata ttctgttatc acgatatcat
      541 atgaaccgct taatagcaag gtttttacca attttcacat gcttttttta gtcatagaaa
      601 cgtaacaaac gaaactgtct ttttcttttg aaaaaaaaac gtcgatatgg taaaatgcct
      661 attttctcct acgagggata attcggatgg acgtcccttc aaaagtaaat gcttttctga
      721 tttgattttc taagaaacgt tcataagaaa aatgcatcaa ttcctcttca ttgacaaaaa
      781 cgacaaatgt aggtggtttg acagcgactt gtgtagcata aaaaatcttc aggcgttttc
      841 ctttatctgt tggtgttgga ttgattgcta cagcatccat aatgatatca ttcaacacag
      901 ccgaagagat acgaagattc tggttcatac ttacttgttc gatcatttca ggcagacgtt
      961 ccaaccgttg tttagtcact gcagaaacaa aaacgattgg agcgtaatca agataccgga
     1021 attcatcacg aatctcttgt tcgaaatcac gcattgtatt ggtttctttc tttacaagat
     1081 cccatttatt cacgacgata ataattccac gaccagcttc atgggcgtaa cccgctactc
     1141 gcttgtcttg ttcccgaatc ccttcttcag cattcagtac catcaaaacg atatcagaac
     1201 ggtcaatggc acgcattgca cgcatcacgc tgtatttttc agtattttcg tatacttttc
     1261 cgcgtttacg cataccagct gtatctatca ttaagaattt ctgaccactt tcagaaacga
     1321 agtgggtgtc gattgcgtct cgggtcgttc cttcaatatc cgaaacaatt acacgttctt
     1381 ctcctaaaat cgcattgatc aaagaggatt taccaacatt tgggcgacca atcaaactaa
     1441 acttaatcgt gtcgtcgtcc tcttcttcag tctcttcaga gaaatacttc actgcttcat
     1501 ctaaaatatc accaatccct agtccatggc ttcctgaaac aggataagga tcgcctagcc
     1561 ctaaggaata aaattcatag atatcgtttc tcatttctgg attatctact ttattgactg
     1621 ctaaaatcac tggtttatta cttctgtata aaattttcgc aaccatctca tctgcgtctg
     1681 tcacgccttc gcgtccgctg actacacaaa tgattacatc tgcttcttca atcgcgattt
     1741 ctgcttgatg cttgatctga tccataaaag gttcatcgcc aagatcaatt ccgcctgtgt
     1801 cgatcacgct gaattctcga cctaaccatt caccttttgc ataaatacga tcacgagtta
     1861 ctccaggagt atcttcgaca atcgagatac gctcaccagc gatgcggtta aaaatcgtag
     1921 acttaccgac gttcgggcgg ccaacgattg caattgttgg atttgccata ttatttcctc
     1981 ctcacaagtt tccaatctca cttagtttaa cgaatgcatt gccaactttc aagcatagat
     2041 tgtcaattaa acgaagtatt tttattcctt attgaaatac taatcgcttt tcaaaagaaa
     2101 aactgagaca aaagcagctg ctttcatctc agtcacagat acaaaatcaa ttatttttca
     2161 gaatcatcgg ttgctttttc ttctacttct tctttcaacg catcacctaa aatgtctccc
     2221 atagtaaatc cagtattttc ttctggtaat tcataagact caacattttt tggttcttct
     2281 tctgaagctg gtttttcttc taaagctttg atactcaatg caatacgatg ttcttctgga
     2341 tggatctcta atactttcac tttcacttcg tcaccttcat gaagcacttc atgtggtgtc
     2401 gcaatatgtt tatgtgaaat ttgagagata tggactagcc cttctactcc agggaacact
     2461 tcaacaaagg caccgaagct tgtcaaacgt ttaactgttc cgtctaatac tgtgccaact
     2521 ggagcttttg tatcgatttc tgaccaaggt ccaggctgtg tgtctttgat tgacaaggaa
     2581 acacgttctt gttcaggatt gatagacaac actttgacat ttacatcatc attgacagcc
     2641 aatacatcac ttggttttgc tacatgacta tgtgaaatct ctgagacatg gactagaccg
     2701 tcaattccgc ctaggtcgac aaatgcgcca aaatcagtaa gacgtgcaac acgtccactg
     2761 agaacatctc cctcatggat agttgaaaga atttcttttt tcttttcttc tctttcgttt
     2821 tccactaccg ctttatgcga taagatcaaa cgattttctg atggttcgat ttcgatgatt
     2881 ttaaagctca atgttttgcc tttatagtct gaaaagtctg caacaaaatg atcttccacc
     2941 attgatgcag ggacaaaacc acgtacaccg acgtcaacga ctaaaccgcc tttgacaaca
     3001 tttgtaacag gtgcttcgat gaccttgccc tcttggaaat ctctttcgat atcttcccaa
     3061 acttttttag catctaaacg gcgttttgaa agtaggtagc tgccgttttc tttatctttg
     3121 ccgatcgtac tgataacgac taaatctaat acatcaccga cttttactac ttcgctgata
     3181 tcttctaccg gcaaagttga taattctttt gccggaacga ctccttcaac tccagcccct
     3241 tcgattccga caatcacttg tttgtcttca atgactaaaa cttcgccctt aacaacatcg
     3301 ccaactttta cttcttgtac gcttttcatt gcgtcttcca ttgactggtt gttctcttga
     3361 ttttgatcaa attctgtcat aacacttgtc ctcctaacca acattctgcc gtaagtacgg
     3421 tactgttttt agtttaattg attattcaaa aaaaataaag cgatttcgtt cgttttcctt
     3481 gaaaaaacaa ttgtttttca ttttttttct taatttaaaa aagaagataa ccttttttca
     3541 aaacaacagc ttttattgct gcaacgactt ctggaatcga tttgccagtc gtatcgatac
     3601 gaacagcatc ctctgcttgc ttcagcggag agacgtccct tgttgaatca taatggtctc
     3661 tttcctgtat ctctttcgtc agtgtttcaa gatcagtcgg aattcctttt tcttggttct
     3721 ctttgaaacg tctttctgca cgctcactta cgcttgctac taaaaagatt ttcacttctg
     3781 cattcggtaa tacagctgtc ccgatgtctc ttccgtccat gacaacgcca ccgcgttccc
     3841 ctatttttcg ttggacagca actaattctt ctctgacttt tccatgtgca gagacttcag
     3901 aaacagcttt tgtgacatct ggttgacgga tttctaaagt cacatctttt gatgctatga
     3961 atacatgctg tccatcttct tgttgcgaaa aagagatagg atactttttg atcagcgaaa
     4021 ctagcccttc ttcatctgaa aaaggtacat tgttcgtaat agctaaataa gttactgcgc
     4081 gatacatggc accggtatct gtataaatat aattcaattc ttttgctaat atcttggcaa
     4141 cggtactttt cccagatgaa gcaggcccgt cgattgcaat actgatttgt gtcatgatat
     4201 aactcctttt tctcagaaaa aaagccgcaa agcgcggcta ttattattta attcttaatt
     4261 cttgaccagg gtaaagcata aagttgtttg gatctaagcc attcaattca aacaattgat
     4321 cagtggtgat ccctgcacgc tcagccactt gttttggacc ttcgcctgct tgaacagtcg
     4381 ttgttgaacc ggctgcagct gatgaagaag gtgttgtttc tgctgcattg ctgcttgaat
     4441 cccctgcttg ataagttgcc tcacttgagg aagtcggtgt tgtctctgct gcaatactgc
     4501 tttctgacgt tacacctgta tcttgagaca cagtagattc ttccgcgatt gtactagatt
     4561 ctactgttga agtctcagtt gactcctctt ttgttgtact tgtagaactt tctactactg
     4621 atgtcgaagt ttcagaagaa gttgctgctg ttgcattgtt gcttgatcca tttctgatcc
     4681 agaaataagc acctgctgga atagcgatac ataagaccag taaaatcaaa aatagcgaaa
     4741 gaaataatgt atttcctttc ttttgttgtc tctgagaact tcttgatgaa acttcatcat
     4801 ctgtatcgta gattggttgt tcccatggtt cttgtgtttc gttattttct gtagattgat
     4861 gtctatcttt tctgctcact gttttacctc ctaaactcta tcgtgtgtat tataccatag
     4921 gaaaaagtgt cttgtcctaa aaaatcaatg ttccatgttt tttttaaata aatttagtaa
     4981 aatcgtttcc caatgaagtt gttcagtctt agaaaaaagc ttcctctttg gcagaagttc
     5041 tgcttttgct ccatcaatat cacaacaatt ctgcggcttt tcggagagtt tttcgccaaa
     5101 ataagctaag atgaattttc tgcggcagtt ttcttcatta atatagcgaa gcatctgctg
     5161 caggcggaat tctttttctt tttcctgacg tttgagccgt tccacccaat tttctggttt
     5221 ttcagactgc tggatcagct ccatccattt tttttgcagc tcatcaaagg gagcttgctt
     5281 tgtggcatat tccaaataaa gctcaaaact ttgtcgctgt tctctagaaa gttgattaaa
     5341 gaaataatgg atacgttcat ccccactttg ataaaaaaga attgctgcac tttcttcctg
     5401 atctctgcct gctcgaccga tttcttgtac atagttttct agactgtctg gcaaatcata
     5461 atggaccaca taacggatat cagatttatc gatccccata ccaaatgcat tcgtagcaat
     5521 gagaaactgc agctgatttt ttacaaactg ctgttgaagt tgtcttcttt gagctgcatc
     5581 aagaccaccg tgatagtatc caactgtaaa acgttccctg aataaatgat acaatcgttc
     5641 gacttctttt tttgttgcac aataaatgat tgccgctcct tgtgctcttt ccatgaagtg
     5701 ttcaagttct tgttcttttt gctgcgtttt ccgaacaaaa agcgagatat tttgccgatt
     5761 gactgattgt ctgatctctt ttggtggtcg atcaaatagt acatgacgta tatctcttgc
     5821 tactaaatct gttgctgtcg ccgttagtgc cagtgtgacc gggtttccta aaagctttcg
     5881 gatttttcct aactgttgat attctggacg gaaatcaact ccccattgag acacgcaatg
     5941 agcctcatct actacatata acgcaatatt ttgttttttc agatgctcta aaagagaagg
     6001 attagtcaac atttcgggac tcaaaaacaa aaatttatat tgcgatagat gacggaggac
     6061 gtatcttctt tcagattgcg aaagtaaact attgaaagca gctactcgtt tctcccctcg
     6121 tttttgtaat tgcgtcactt gatcttccat tagagaaagc agcggtgaca cgatgatgac
     6181 cagaccttcc attaaatacc ccgtcaattg atagcaaagg ctttttcccg ttcctgtagg
     6241 caaaatagcg agagtatctt ctccatcaag caacgcctga ataatttctt cttggccggg
     6301 acgaaatgaa tcaaatccaa aatatttttt taattcattt attaacattc tgtatcgctt
     6361 cctttctcaa tagatagatt tgatacaaac gaaattctcc ataatctaat tgtccatcta
     6421 cattccattc gctaaagcgc cactctcgca cggaatcctt atttggttcc aaacgttcga
     6481 ttgtttctgc agagagaatc cactcgtatg gaaaatcatc aaaaaacaag gcccactcaa
     6541 taagatgatc tgttactgtt cctcttttta aatgacggat tgccatgatc tggtcaattg
     6601 tctgaccatt cataaacatc tgcttggtga tcatcatgct ttgattgaaa ttttgctgta
     6661 ataatgaatc gatcaaagcg tgccaaagcg aatctggccg tttttcgatt tgtgctaaca
     6721 aaaggtggat acatctgctt tgttgcagat aaacctctga ctcatcattg ttttttgcca
     6781 gctgataagg aagcagccct gttcgctcat ttccagataa ttggttagct aaaaaatctg
     6841 ctgcttcttc tggtatctcc gaaaacagct gcaccaaact ctcatacgca gtatcaatca
     6901 aaatttcacg tggcaattgg ctttcactaa gccatttttt tagttggaaa gtataaaaag
     6961 gacttgtctc tgctggaaga tagtcttgaa tacccgttgc cagattagaa attacttgaa
     7021 cagcaaattt aatgagccgc caactagttt cccctgttct gccatagcgg tcaaaacgca
     7081 aaccagtatg ttctatttga tgttcggaca acatatcagc ccctgcaggc gttagctttg
     7141 cttcattttc atttatttcg atccaacctt gctgcgcaat tttttgcaaa atttgataaa
     7201 acttatcctg cttcaattct ggaaaactgt tatggataaa caaaagttcg tgggtaaatc
     7261 cataaataag tactgaagtc gttcgttttc ccacaaggag ttggtaaaga gaactaatcc
     7321 gcagcttgtg tcctgatgaa aatagcgata aaataaaaac aatcatatta ttctccttaa
     7381 gttaggatgg ttagaaatgt cactactatg taaacttgta cctgaacgct gtattgcatg
     7441 cggtctttgt caaatcgaag cgccagatat tttcgattat gatgaagaag gaatcgtttt
     7501 atttgcccaa gaaccagagg ctcatcaaca gttcgtgatg ccggaagaag aaacatatgt
     7561 aaaaaaagcg tatcaaaaat gtccagttcg agcgatttta ttagaaaata aaatataaat
     7621 ataaacgaaa ctttaaaaac gtacactaag ttctctaaac ttgaaaataa gccgggatct
     7681 gtttctcttg ttccgtgaaa tcccgactta ttttgaaaga ttcatttgct atctatagtt
     7741 aattgactag ttttttcacg gaccctatag gacccattta tattatttca actttttcag
     7801 ccagttttcc aatgtattga cgatcacagt ttgctggtct gcgttagaaa tttctgcctc
     7861 tccatctcct ttttgctcac catagctgcc aaaacctcca tgatttccgc cattgattga
     7921 tacatactct gttctttccg gtaaatactg cttagcttct tgataagctt cctgattcaa
     7981 tactttatct tttgtcgccg tgatcgataa aacaggaaca gctgattctg tcaatgttcc
     8041 ttttttgtcg ggataacttg ccatgaagaa tacccctttt aaatgtttgt ctgaatgatt
     8101 cttattgaca taacgacttg ccattacgcc acctaatgaa tggccaccga tcacataatc
     8161 ggaatttgga aaatcttctt tgaccttatc cgctttgttt ccgcccatca ctgctagatc
     8221 aagtggcatt ttgacaatag cgactgaaaa gccgtttttt gctaaatctt gcgcccaaat
     8281 actataactt tctggctcta cgagagcacc aggataaaaa ataagtaatg gagactttcc
     8341 atgattcttt ttctctcctt caaaaaataa gtaatcttct ttgttttttc cttcttttac
     8401 caacacttgc gcttctgacg atggttcgta cgtattttgc tgtatatagt aataaccggc
     8461 tccaccgagt aatcctaaaa tgatgactaa gccaattagt attcgtctaa atattttcac
     8521 tttctcccac cttttctatc tgagtgaccc ctttttctta atcaagtatg attatacctt
     8581 aaaaaaataa gagagaaatg caaactttcc agcatcaaat aaaaaaagac ggaatatcca
     8641 tttgaatatc cgcccttttt gtatgtttat ttttatttag cacataaacg atacacagct
     8701 tctgcataaa tttccattgc tttatacata ctacttaatt cccatcgttc attcgcctgg
     8761 tgcataaagt caggagtatc agggaacatc gcaccgaatg ccacacactg gttcatcgta
     8821 cgagcaaaag tagcgccgcc tgatacaaac ggttcagtca tgtctccagt aatatcgcga
     8881 tatgtcccca atagattttt cactaactca ctgtctagtg gcacgtataa tgaatcaagg
     8941 aagtcaaatt cttcataagt caacccatat ttttctgctg ttttagttaa tttagctact
     9001 aaatcatctt tcttgaatgt aacagggatt ctcatatcta caccgatttt tgtttgttct
     9061 ggtgtgattt ccaaacttgc aaagttcatc gttagctcgc cggattgttc atcttctgtt
     9121 ttgcccacga cagcttcacc agttgcattt tcttgaacta attttcctaa gaaattgatt
     9181 gggccaaaat caaatacttc tgaaagagca attgccagac gagaaatagc attcactcct
     9241 tgtgctgcat ctttcgcgtg gatactttta ccaagaacga cgatgccttc accttgttct
     9301 tcgaaatcga attcgtgttt tttcaatgct tcttttactt cagaaagctt ttctccagag
     9361 taaggagctg catcaggaac aacattcaac gctcctccag cttttacaga aaactcgttc
     9421 gttcctggtc ctgtcaagta agcttgcaat aagccttttt ctgcataaat taaaggaaat
     9481 tcagcatctg gcgcaaatcc ttgcgtaatt ccttcttctt tttcgttata tttttctaaa
     9541 caacgccata aattttcttc atctgtacca aagataaaac gaatacgtgt cttgaattcc
     9601 acgccagcat caatcaaagc tttgacggca tacattgccg caatagaagg acctttgtca
     9661 tcttgggatc cgcgaccaac taaccagccg tcttttatag ttggatcgaa tggttttgtt
     9721 tcccaattat tttcgtcccc tgctggaaca acgtccatat gacacaagat accgaataat
     9781 tcatctccag agccaatctc tgaataaccg taatagcctt ctggatcttt aaatgttcta
     9841 aatcctagct tttcactgat ttccaatact ttatccaaag cttcaatcac ttttttaccg
     9901 aagggatgtc cttgtcctga atctgcttca tctagtacgg aaggaattcg gatcaattcg
     9961 ctcaatgatt ctaatgcttg ttcatgatgt tgttctgtca caaatttttt catgatatta
    10021 tcctcctaat atgttaaaaa gggtcatgtc aaattcctcc gacacaacct cttcttctca
    10081 aataatgacg ttttaagcct gctccatcag caagcagaat gttcttaaca aatgatgaaa
    10141 gaaaaaacac tcactgaatg gagctattga cttgtccacg tgcttatcga tagccgttta
    10201 tcggtttctt cattcttatg atagaccttg tacctgtatt tgtctaggtt tagaacattg
    10261 ctgctacacc taggatcaca cagatggcta caaataatat cgcaattaat ttaccggtaa
    10321 atttccacca cactgaaaca tcgaaacgag caattgctac agcacccatt acgatagcag
    10381 atgttggtgt aattaagttt actaaaccag atgcagattg ataagcagtg attactaaat
    10441 ccttaccgac gccggcaaat tcacccatag gtcccatgat tcccattgtt gcagcagcta
    10501 agccggaagt tgaaggaatc aagaatgaca tagggatata gaaaataaat gtaataatga
    10561 tgaatacact tgaagataat gaacttaatc cttgttcgcc ccaatgtaag atggtgtctg
    10621 tgattaatcc attgttcata accacttgga taccacgagc aacagctact acgattgcta
    10681 caccgatcaa atcagaagca ccagctaaaa attcagagac aaattcagac tctttcatgc
    10741 cataagtgat tgctactacg atggacatta ctaagaataa catagtaatt tctgggaagt
    10801 accagtcacc taatggaagc atgcttttac ctagaaccgt acctagtacc ggaaggtttg
    10861 ttaaccagtt tgtcaatgat tcaaaaatcg tgaaattcgc attcaaggtt gtccaaggaa
    10921 tcaaactgat gatcatgata ccaaaagtaa taaagaacaa tacattaaca tgtttttgtt
    10981 ttttcgtgat tacttcttga cgaccgattg cttcaatatc gaaatgcttc atatcttctt
    11041 tacgttggtt gtatactaat gattttgttg gatctttttc gatctttgat gcataacgat
    11101 acacatatac aatagaaata gctaacaaaa taacgaacat caagaatcga agaccaatac
    11161 cttcacccat cgaaatccca acagcttgtg aagctacgcc tgttgcaaaa ggatttaccg
    11221 ttgaagctag acagcctact tgagacccta ctaatacgat tgctacagct actactgtat
    11281 caaagcctac agccatcatg actgggatca gtaaagcata gaatggaatc gtttcttctg
    11341 ccattccgta agtagagccg cctaatgcaa ataacagcat caatactgga ataagcattt
    11401 tttcttttcc tttgaatttc ttcacaactg aagcaatccc ggcatctagt gcccctgttt
    11461 tgttgataat acctaaaaat ccaccaacaa ccaaaatgaa gaaagagatt gggattgcag
    11521 caggtgtttc tttagttagc tcccccgctg gtacacctag catcccattg attggcgcca
    11581 tgaaaatatc ccacagccct tgaggatttt gttgtactcg ttcatatgat ccagcgacga
    11641 tgttgcctgc atcgtctaca ctatagtgcc cagctggtat aaaccaagta agtacagcga
    11701 ttactgcaat aataataaat aagaccgtat acgctgaagg catttgaaat tttttctttt
    11761 ttgtttgttc catcttcttc ttcctttctt ttccgttaga gacaacaatt ttggctctaa
    11821 tgttatttta tcaaaaagag tatcagaaca aaaataataa cacgcatttt gtaaaacttt
    11881 tgttcaaaaa gttcgttttt ccctattccc tcctcttttt tcaggttttt aaagctttct
    11941 tctttttcat tgtagcgttt cctttttttt ataaacaaac attttcgtct tttaaaagga
    12001 gaagaatttc acatttgcaa agaattgatt gatttttatg cataaatcaa aaaaatactc
    12061 aaaacaaaca aataaaacgt ttacattatt gcatgtcttg tatttttttc caaaaaaaaa
    12121 gaccaagaaa tttcttgatc tttttgatat ttatttgact gctgtatgac gttgttcgaa
    12181 ctgatgttgt tttcgactta accatggaag aagttgcgca tgcagcacta aaaagacagc
    12241 actcacgatg aatcctttga tcaagttgaa aggaacgatc ccaatcagta catagtttgc
    12301 taaagacatg cccagcatct gtgttgcgtt cagccctaaa aacattaagt aaagaggcgt
    12361 aataacgaaa taatttgcga tactcataaa aatagttaga gcgatggttc ctgtaatgac
    12421 acctaaaaat ttgtttcttc ctttatgctg tttctttaca ctaaagaaat aataaatcgg
    12481 gaatgtaaag atcgttgttg ataagaaact agcagtgtct cctaccaaat tatccggaga
    12541 aaaacctgta gtcagcagat gtaatactga acgcaagaac gctgttgcaa ctccggccgc
    12601 tggaccgaat aagaacatgc tgatcaatac cgagatatca ctaaaatcga tcttcaaaaa
    12661 actaaaagcc ggcatgatcg gaaaagcaaa atactgtaaa actaatgcga tcgcagcaaa
    12721 catcgctact gcaaccattt tctgtacacg ggtgttcttc atttgaaatc ctcctgttag
    12781 gactcctctt cagcgaactt tttgacgttt ctctccaaat gaaaaaactc tattttccag
    12841 ggaaaataga gttagagtta tttgatcaag cgtcgtcaaa taagctctat cttctttatc
    12901 cagactatac tgtcggtatc ggaatttcac cgattcagct atttttttgc aaaataggtc
    12961 gtggactata accaccggtc gggaatttca ccctgcccct gaagacgaac cttatataat
    13021 ttttgtttac atattcatta tacatatcta ttcaaaaaac gcaacatcta acacttataa
    13081 aaagtaagtg ttcattttga gtggttcagc aaactgctga cttctttttt gttcagttca
    13141 cggtaatccc caggacgtag gccttgtaaa gtcagatctc cgtatttttc acgttttagt
    13201 ttttgcacag gaagaccaac tgcttgaagc atatttttca cttgatgatt acgtccttcg
    13261 tggatcgtca attccacgat actgtggttt gtcttaggat ccactgataa aatttggaat
    13321 ttagctggag atgtttttcg tccttcgatc tttattcctt ttgtcaaagg tgcaagcatc
    13381 gattttgtag cgatcccttt tacctttgca acgtaaactt tatccacttc atgttttgga
    13441 tgtgtcaggc gctgagcaaa atctccatca tttgtcagta gcaagatccc cgaagtatcg
    13501 taatccagtc gacctacagg atagatacgt tcttttacca tcggcaaaag atccgtaaca
    13561 acttttcttc ctttgtcatc tgcaacagca gaaataactc ctttaggttt gtacaataaa
    13621 tagtaaccgt attcttcttg ataaattggg acttcatcca cttccacagt gtcatgtttc
    13681 ccaactttta tccctaattc ccttacaact tgtccgttta cttttacacg tcctgcaagg
    13741 atgaattctt ctgcttttcg acgagaagtg atgccagcgt gggcaattac tttctgcaat
    13801 ctctccatta caattattct cctttattca ttccatcaaa gaatagatct ggtgacacgt
    13861 cttcttcaag tgaaatttcc atttcttgtg tatcaggcag ttcttctaat gatttcaaac
    13921 caaaataatc taagaagtag ccagttgttc catataatat cggccgacct ggtccttcta
    13981 ctctaccttt ttcttcaatc agtttatggg cagctagacg ctgtaccgct cctgaaacct
    14041 gaactcctcg aatctgctcg atttcagctc ttgtgattgg ctgtttataa gcgatgattg
    14101 ctaaggtttc gacggcggct tgagataatg tgtttgatgt cccttgcgca tatcgcttaa
    14161 gtaagggagc cagctctttt ttagtcgtta atacataatg gctttccgtt tcaaaaatat
    14221 gcaaagctga gtgcgagttt tgagtgtaag attcttttaa ttctttcact aaacttgtga
    14281 cttctgcttc gctgagattt aacagtccgc ttaattcttc attactgatc ccttcctcgc
    14341 caacaataaa aagaagggct tcaagttcac ttaatttcgt catgttcggt atctcctact
    14401 gctggataaa gcataattga ttcatagttt tctttttgtt gcgcaatgat ctgccctttt
    14461 ttcatcaatt ctagcaaagc cataaaagta gtgacaactt cacttttaga aggtgactca
    14521 aaaaaagaat cgaaagtaca gccatgcgca tttcttttta tacgctcttc gataaatacc
    14581 attcgttctt cgatcgttgt gtcatcgggc gtgatcgttt tttccacttt ttgagaaaat
    14641 ttcttacgtt ctaagatttt ctgcatggca cggatcaaat cgattttttt gacttgtcct
    14701 cgcttcaacg gcttttcagc atccgctaac ccatcgatgt tcataggttc ttttgtgtaa
    14761 taaagacttc gttcctctgc tttttctgtc agtctttcag ctgcatattt atatttacgg
    14821 tattctaaaa gctgagtgac caattcttct cgaggatctt cttcccataa ttcttcatcg
    14881 tctgtgccga attcttggac aggaagcaat gtcttgcttt tgattgccat caatgtagca
    14941 gccatcacta agtattctcc tgcaacagct agctcgagtg ttttcattgt atggatataa
    15001 ttcatatatt gctccgtgat cgtagcgatc ggtatatcat atatatcgat ttccatttgc
    15061 tgaatcagat gaagcagcag atcgagagga ccctcgaata catctaattt aatattgatc
    15121 tccgtcaact cattcactct ttcttctttt tctttgctag ccattttcca atgtaaggct
    15181 ctgtgatttc agttgcacgg atggagacat ccgggtactt ttcctgtaat tcatctaaca
    15241 tttgaaagcc catattctca ccgcgataag acggattcaa agaaatgtca tggatgatca
    15301 gctgatcgtt cgttgcccag taaataccaa taatcccttg aatgttggtt gaaccttctg
    15361 gcgtaaagaa aaaaagttca taatcgtctt cagattcgta cgtatcaatc tccttcaaca
    15421 aagaagtttt acctgtcagt ttcttatgga aactcaatag tcccatagca attttacggt
    15481 tttctttccg gtaatgtgtt aacatcttct caccttccta tgactaagcc cttggaaaat
    15541 gctgcttata aacatccgtc attcttttct tcgtgatatg tgtataaatc tgagtcgtag
    15601 agatatccgc gtgacctaac aattcctgta ctgtccgcaa atcagctcca ttttctagca
    15661 gatgtgtggc aaagctatgc cgcagcgtat gtggtgttac ttctttgtaa atcccagcct
    15721 ctcgtactaa ctgcttcaga tttttccaga ttccttgccg agaaagacct ttcccatgat
    15781 tattgacaaa tacatgcatt tcagatgcgt cctttacaag taatggacgt gcttcgtcta
    15841 agtagcgttc cagccattgg atcgcataat cacctaaagg aatgatccgc tctttatctc
    15901 cttttccaac tgtctgtacc agtccaagag aaagatgaag atctcccaat ttcaatccaa
    15961 tcaattcact gacgcgcatc ccagtagcat acatgacttc caagattgca cgatctctta
    16021 tccctaacgt ttttgtcgta tcaggtgctt caatcagctt ttctacttct gtcagagtca
    16081 atgtacttgg taatttctgt gctttcttcg gcgtatcgat atgttgcatc ggatcatgat
    16141 cagtgatacg ctcttgccgt aaaaactgat ggaatcttct gagacttgag atcatccgag
    16201 taacagttgc tgtcgctttt ttttcttcat gcaacttctc cagaaaacgg atgactaaaa
    16261 agcgatcgac atcctgccat gaagcaattt tctgctcctg tagaaaatgc aagtactgtt
    16321 ccaaatcacg ttcatagctt tgtcgtgtat tggcggacaa tccccgttca atattcaagt
    16381 agtggagata atcgttgatt tgctctttca taataatccc cctcatgcct ctctatcata
    16441 tcagataccg cttcattctg atagtctttt tccataatct gagcaaagaa aaagccgtct
    16501 agacactcag acggactggt ttctttt
//
LOCUS       DACDLM010000062        16136 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.063, whole genome shotgun sequence.
ACCESSION   DACDLM010000062 DACDLM010000000
VERSION     DACDLM010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16136
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.063"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..1759
                     /locus_tag="IV356_002123"
     CDS             <1..1759
                     /locus_tag="IV356_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAP9015789.1"
                     /translation="NLEQKDVVESEDNLYVNACPGSGKTRVLTRKIAYQAIKHDGSLK
                     RIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYPFKMNLSRVSKGF
                     TIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQYTQVSEMYHTMLE
                     KNKEIDFDMILLVAYKILTVNSNVARNIASNIRAIYVDEFQDTRELQYNVIAKLLQNN
                     PQIQSMFVGDIDQAIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCYRSNQRLVDFYSN
                     FQSCPYEIESRGNNKNDRGFISYDCKVTKEDLPNIIKNIIKEKIESGIHEKDICVLAP
                     QHYPLFSLGEYLKKELPYCNFDAINISPIKVNNHSLFFKLAILYFTESGEKVRRRKLI
                     ANDILIILKNEFGIEVKDYFIDLDLLQLINSVKRMYSGDDNGVDLYKFVTKHIFVNLN
                     IDEKNYPSIFKHYLFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGITLTTAHKVKGNE
                     YDTVIAINLLNGKIPHWNEIFNVSDKGISSARKLLYVICSRAKNNLFLFSEVGYFTSK
                     GDLLYPTQLLDKIEFDYNI"
     gene            1959..2273
                     /locus_tag="IV356_002124"
     CDS             1959..2273
                     /locus_tag="IV356_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018705633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAP9015790.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            2294..2671
                     /locus_tag="IV356_002125"
     CDS             2294..2671
                     /locus_tag="IV356_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAP9015791.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            2681..3454
                     /locus_tag="IV356_002126"
     CDS             2681..3454
                     /locus_tag="IV356_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015792.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            3476..4879
                     /locus_tag="IV356_002127"
     CDS             3476..4879
                     /locus_tag="IV356_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAP9015793.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            5061..6245
                     /locus_tag="IV356_002128"
     CDS             5061..6245
                     /locus_tag="IV356_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAP9015794.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            6242..6532
                     /locus_tag="IV356_002129"
     CDS             6242..6532
                     /locus_tag="IV356_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015795.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            6529..6750
                     /locus_tag="IV356_002130"
     CDS             6529..6750
                     /locus_tag="IV356_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015796.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            6792..7571
                     /locus_tag="IV356_002131"
     CDS             6792..7571
                     /locus_tag="IV356_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HAP9015797.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLN
                     EARNRHSLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            7638..8132
                     /locus_tag="IV356_002132"
     CDS             7638..8132
                     /locus_tag="IV356_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAP9015798.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            8188..8826
                     /locus_tag="IV356_002133"
     CDS             8188..8826
                     /locus_tag="IV356_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015799.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            8898..9293
                     /locus_tag="IV356_002134"
     CDS             8898..9293
                     /locus_tag="IV356_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP9015800.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            9277..11730
                     /locus_tag="IV356_002135"
     CDS             9277..11730
                     /locus_tag="IV356_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP9015801.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            11727..13754
                     /locus_tag="IV356_002136"
     CDS             11727..13754
                     /locus_tag="IV356_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015802.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            13751..14773
                     /locus_tag="IV356_002137"
     CDS             13751..14773
                     /locus_tag="IV356_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAP9015803.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDDETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            14790..15719
                     /locus_tag="IV356_002138"
     CDS             14790..15719
                     /locus_tag="IV356_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP9015804.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            15964..16080
                     /locus_tag="IV356_002139"
     CDS             15964..16080
                     /locus_tag="IV356_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HAP9015805.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
BASE COUNT         5527 a         2642 c         3159 g         4808 t
ORIGIN      
        1 aaatttagaa caaaaagatg ttgtggaaag tgaagataac ctttatgtaa atgcatgtcc
       61 tgggagtggg aaaacaaggg tacttacaag gaaaattgct taccaagcaa ttaaacacga
      121 tggatcacta aaaagaataa ttgctatcac atacactaat agagctgctg aagaaattaa
      181 ggaacgccta agtttactta gtatagatga tgatattaat atttgggtgg ggacaataca
      241 tcagttttgt cttgaattta ttatttatcc ttttaaaatg aatctctcaa gagtatcaaa
      301 aggatttaca attattgatg attatactca aagagcttac gtcagccaaa ttaataatat
      361 gctgaattta aatctcaaaa cgtatgaact gaacaaaatt gatttgtcac tttctcatga
      421 ttttaaaatt aatgaagttc agtatactca agtttctgaa atgtatcaca ctatgttgga
      481 aaaaaataaa gaaattgatt ttgatatgat tttactagta gcgtataaaa ttttaactgt
      541 aaacagtaac gttgcacgta atattgctag taatataagg gcgatttatg tggatgaatt
      601 tcaagatact agagaattac aatacaatgt aatagctaaa ttacttcaaa acaaccctca
      661 aattcagtca atgtttgttg gagatattga ccaagcaatt tatggatcat tagatggtat
      721 agctaaatca gttgaagaac tagaaatgct aactagtcac acttttcaat caaagacgct
      781 acatggctgt tacaggtcta atcagagatt agtagacttc tactctaatt ttcagagttg
      841 tccttacgag attgaaagca gagggaataa taaaaacgac cgtggtttta taagttatga
      901 ttgcaaagtt actaaggagg atttacccaa cataataaaa aatataataa aggaaaagat
      961 tgaaagcggc attcatgaaa aagatatttg tgtacttgct cctcaacact atcctctgtt
     1021 ttcactgggt gagtatttaa agaaagaatt accgtattgc aattttgatg ctataaatat
     1081 atcaccaatt aaggtaaata atcatagttt atttttcaag ttagcaattt tgtactttac
     1141 tgaatcaggt gaaaaggttc gaagaagaaa gctaattgca aacgatattt taattatatt
     1201 aaaaaatgaa tttggaatag aagttaaaga ttattttatt gacttagatt tattacagct
     1261 aataaacagt gtgaaaagaa tgtatagtgg agacgacaac ggtgttgatt tatacaaatt
     1321 tgttaccaaa catatatttg ttaatcttaa tattgacgag aaaaattacc cgtctatttt
     1381 taagcactat ctatttttta ttaacgaagt agaagatcgg ataaaaaata attcattatc
     1441 tagtagtgta tctagtttta agaagatgtt taaatctcga gatggtatca cacttactac
     1501 agcacataaa gttaaaggaa atgagtatga tactgttatc gctattaatc ttctaaacgg
     1561 gaaaattcct cattggaatg aaatttttaa tgtttctgat aaaggaatta gttcagcgag
     1621 aaaactacta tacgtaattt gttcaagagc aaaaaataat ttatttcttt tctcagaggt
     1681 gggttatttt acgagtaaag gagacttgct ttatcccact caattattag ataaaataga
     1741 atttgattat aatatttaaa atacctaggt agtcgttgtt ttaaatatag taggaatcgg
     1801 acgctcagta cggagcgtct atttttttac ccaattttga aaggaagtga acttatgaaa
     1861 ataaaaaatc aagaatcaaa aggtcgctct ccccccttta aaaccatcac acaaataaga
     1921 ttcattcaaa cataaaaaca gaaaggatag gtaaaaatat ggaacttaaa tatgtcattc
     1981 ccaatatgga aaaaacattt ggacaattag aatatgctgg tgaagggaac attgaacaac
     2041 gtcgaataaa tggcagacca accattctct ctcgtagtta caatttatac tcaacgattc
     2101 aacgagcaga tgatattgtt gtcattcttc cctccgaagc tggcgagaaa cattttgaat
     2161 ccgacgaaaa agtcaaactc atcaacccac atattaccgc agaaggttat aaaattggca
     2221 atcgaggatt taccaattac attatgcacg cagacgatat ggtgaaagca taagaaagga
     2281 aaggtgaaaa aatatgagat tagcagaagg tattgtgatt gaaaaagacc agacatttgg
     2341 cacattgaaa ttttccgcct tgcgtcgtga ggttcgtatc cagaatgaag atggtacggt
     2401 ttccgaagaa attaaagaac gtacctatga cttaaaatca aaaggacaag gacgcatgat
     2461 acaagtcagt atccccgctt ctgttccttt gaaagaattt gactacaacg cagaagtgga
     2521 attaatcaat cctgtggcag ataccgtagc gacggctact tttcgagggg cagacgttga
     2581 ttggtacgtg aaagcagacg atcttgtatt aaaaggacag acaaaacctc atcagaaata
     2641 taaaaaagaa gcgtccgaaa gtgaaaaata ggtgttgctt atgacaaaca caccattgat
     2701 tttgaaagaa attccgaagg atgaagccat ttcttttatt cggcaatacc attattcaaa
     2761 gatactccct agattgtgta aatactttct agggattttt tcagaagaaa aattattagg
     2821 cgttgtggaa ttaggctggg gtacgcaacc cctacaaacc atacgcaaac tctttcccga
     2881 cagttccctt caaaccacag attatttaga aattggaaag atgtgttttc ttccagaaat
     2941 gaatcaaacc aattattttg gcagtcaagc tctttcagct ctaattaagt ggttgaaaga
     3001 acatacggac tgtcattttt tatatacact ggcagatgga attgagggaa aatgtggcta
     3061 tgtctatcaa gcgtccaact tcttttactg cgggtatttc aagacaagtg tctatcgtga
     3121 taagcagtca tgggaaaaga tacaccctcg aagtgctcgc cttttattag aggaaaatgc
     3181 tcgctttgaa caggtagaga aaaagcattg gctttcccag gcattttgcg aatacaaagg
     3241 gattgagaaa atcaatggac gcatgtttcg ctatctctat ccgttgacaa aagaagcgaa
     3301 aaaactgtta ggacacactc tctatcgacg tcattattat ccgaaagaaa aaaatttacg
     3361 ctttgaaaag cgaatcgctt atcagaaata tgaagccatt tctcaaccaa cttttgataa
     3421 acaggctcgt atctacaata cacaattatt ttgataggtg gaaaggagga tttttatgcc
     3481 attgcttcat gacagaggag agcgaatcaa agccaacgat aagcacttgg tctatcattt
     3541 tgtactaatt tcattgctgg tagtttttct agtcgtccta ctcccttttc attggagagc
     3601 gttacaatcg gtgaactggc aagcagttca gttagataca tttttctatc aacttcatac
     3661 gccatacttt tggagcagta ttctcactgc tctttttgta tgcggactta tcagctggct
     3721 ttattatcac tatcgtatag attctataaa acagttagag caccgtcaaa agttagctcg
     3781 tatgatttta gaaaatcatt ggtatgaagc cgaagaaact caatcagagg gattctttaa
     3841 agatttaccc agcaagaaaa ccaaacaacg aatccgccat tttcctaaaa tatattatcg
     3901 aatgaaagat ggactaatcc atattcatgt agaaatcacc ttagggaaat atcaagatca
     3961 gcttttgcac ctagaaaaca aactagaaac aggattgtat tgtgaattag tggaaaaaac
     4021 gttgaaagat tcttatgtag agtatgtcct actttatgat actattggca atcgaattgg
     4081 cattgaagac gtggtagctc aagatggacg tgtcaaattg atggaatcgg tctattggga
     4141 gttcgattct ctccctcaca tgttaattgc tgggggcact ggtagtggaa aatcctattt
     4201 tattctcaca ttgattgaat ctctcctgca tacaaatgca aagctttata ttcttgaccc
     4261 taaaaatgct gatttggcag acttaggggc ggtcatgaat aatgtctatt accgtaaaga
     4321 agatatgttg gcatgtatca atcaatttta cgaagatatg attgatcgca gtgaaaccat
     4381 gaaacaacac cctaactata aaacaggaga aaattatgct tatcttggtt tgtctgccaa
     4441 ttttcttatt tttgatgaat atgtggcaat gatggatatg ctaggtcgtg aaagtaccac
     4501 cgttattcat aaactcaaac aaattgtaat gttaggacga caagcaggct tctttttaat
     4561 tcttgcctgt caacgtccag acgcaaaata ttttagtgat gggattcggg acaactttaa
     4621 cttccgtgtg gctttgggtc gtatgtctga aatgggcttt ggtatgatgt tcggaagcga
     4681 tacacaaaaa caatttttct taaaacccat caagggaaga ggttacgtgg atacaggaaa
     4741 aagtgtgatt agtgagtttt atacacccct tgtaccaaaa aggtacgatt tcttaggaga
     4801 aataggaaaa gtcattcaaa aaaagcaatc tgagcctgta ccgcacgaag tgaaaggtac
     4861 aggttcagac ttgctttgat tggtgtggcg ttagccacgc caatccttta gccccctcta
     4921 tctaacaggg gggcacaaat acaactgaaa acaggcaatt ctcatcaacc aatgttgatg
     4981 gtacaaagga ttgcggaaaa tatgaaaggt gtaaactcaa gggtcatagt ttacatcttt
     5041 tttagattgg aggtttgcga atggaaaacg aaaaaatttg gattaaggaa ttgaaagaaa
     5101 agcgactggc ttatggcgtt tctcaaaata aactggcggt tgcttctcat attaccagac
     5161 cttacctatc ggatattgaa acaggcaagg cagtccctac tcaacaggtg aaagaagatt
     5221 tactgaacgc tttggaacgc ttcaatcccg ataacccatt ggagatgtta ttcgactatg
     5281 tacggattcg attccctacc aatgatgtgg ctcaaattat cggtgaggtt ttacgtttga
     5341 atatggatta tatgctacac gaagactttg gctattattc ttatcccgaa cactatcgtt
     5401 tcggtgatat tgttgtccta gtctctcatg atgtaagtaa aggtgtttta ttagaactga
     5461 aaggaaaagg ctgtcggcaa tttgaaaact ttctattggc tcaacatcgg agctggtatg
     5521 atttctttca agattgcatg gaacataaag gtattttcaa acgcttggat ttagctatca
     5581 acgataaaac agggattttg aatattccag atttggcaaa gaaatgtaaa caggaagaat
     5641 gcatttccgt ctttcgaagc tttaaaaatt atcgcagtgg tgaattggtt caccgtgatg
     5701 aaaaaccata catgggaaac acactttata ttggctcatt aaaaagtgaa gtctatttct
     5761 gtatatatga gaaagattat gagcaatacg tgaaaaatga tgttccctta gaagacgcag
     5821 aagtaaagaa tcggtttgaa attcggttaa aaaatgaccg agccacccaa gccatgaaag
     5881 atttattggc acatcaacag gcggaaaaaa cagcctttga aattatcaat cgctatatcc
     5941 gctttgcaga taaagacgac actaaacgtc ggagtgattg gaaaactaat gaacgttggg
     6001 aatggtttat cggtaaaaat cgtggagcat tacgcctaac cacacagcca gagccttatt
     6061 cttttgaacg aacattgaac tggttacatc atcaagtcgc ccctacatta aaaatcgcaa
     6121 gcattttaga tgttctcaac ggtacaacca ttatctccac catgattcag gaagccaaac
     6181 tgacagaaaa acatgagaaa ttaattgaac aacaacatct agccatggag gatttgatta
     6241 catgagcctt ttaacaaaag aattaaagaa gttagggttt cagtgtggca ttgagtttca
     6301 agcgtatata caaaatacag ggaaatatac gtctctcatt attgagggaa aacggcaagc
     6361 tggtgatacc atctatacct atgattttta caaggtgaga ttttataata attataccaa
     6421 tcgagtaacc gtctatggag agcatttaac cccttttcaa ttattaaggc gtgtaaaaag
     6481 ctatatctat tatcgagaaa aatatcttaa ggaaaggagg acaatcacat gaattttggg
     6541 cagaatttgt acaactggtt cttggataat gcacagtcat tggtattgtt agcgattgtt
     6601 gtcattggac tgtttttagg ttttaaacga gaattttcaa aactcattgg cttcttgatt
     6661 attgctctaa tcgccgtcgg acttgtgttc aatgcagctg gcgtgaaaga tgtgttatta
     6721 aacttattta accgaatcat tggtgcttaa cagatatttt tcatgataaa ataggaagta
     6781 tatattttgt tatgaaagga tttatgaata tgtttacaaa tgatcaattt aaatctcttt
     6841 taattaaaac attagaaaga aagagctctt caaattatta tgaaggaggt aacgagattg
     6901 tttctaaaat gaaaatatca gaggtaactt tagatgagac tgacgatttt acttattata
     6961 aaggatataa aaagggctgg aatacgcttt gcacatatct taaaataaga gttccttttg
     7021 atgatttaga cttttttgaa agtcataaag atttgattac ccagacagca agctccatat
     7081 atgataaaca aggtgataat gtattagtgg atactatttt agtaccactt ccagagaatt
     7141 acgaagtaat taactttagt cagttgaaaa ttagtgatgt ggtttcacaa gctattgaag
     7201 acgctgagtc ttttatgagt aatggtgaat atcaacgtgc ctttgacaga gttcacactg
     7261 cttttcatgg atatttaatt gaaatactaa aaaaatatga aattacagtt cctagagacg
     7321 aaaatctatc taaattatat agtaggatac aacaattaat tgaaaaagaa attcaaccta
     7381 ctgaacttgc tgatatagtg aagacaacga taaggtcatc aaatggaatg attagctctc
     7441 ttaatgaagc aagaaatagg cattcacttg cacaccctaa tacaaatatt attggaaaga
     7501 gagaagcaaa actaataata ggtatttcaa gtacagttac agattatatt agcggatacc
     7561 ttgataagta gcgtcattaa ctgattgcta ctttttttat gactattttt ataaaaagga
     7621 tgtgataaga attggaaatg aaagtctatg tggcaaattt aggacggtat aatgaaggtg
     7681 aattagtcgg agcatggttt actccaccaa ttgatgagga agaaatggca gaaagaatcg
     7741 gtttaaatga ggactacgaa gaatatgcaa tacatgattt tgagcttcct tttgatgtgg
     7801 acgaatacac gccgattagt gaaatcaacc gtctatgtga agccattcaa gaaatcgaag
     7861 gtacacctat ttataatgaa ctcaaagaaa ttcaaggcat gtggtttagt agcttggaag
     7921 aattactgga aaacaaagag gatattcatt gttatagtga ttgtgattcg atggaagatg
     7981 tcgcccgtta ttacgtggaa gaaacaggac agcttggtga agtcccttcc aatttacaaa
     8041 attatattga ctaccaatct ttgggacgtg atatggaaat agagggtaat tacctagtta
     8101 cctctcatgg ggtatttgaa tattgtcagt aagtttaaca atccgtgtta taattaaatt
     8161 aataaatagc acggagaggt ataaattatg gtaaatgtat ttgaaaatct taaactatta
     8221 aaactagaca tgaaagataa aggctgggtg atagattcct tttactttcg ttacaaacag
     8281 caaaattata ttgtacttgt taagctattt gaaaaagagg aaaaagttcc agaatatgct
     8341 ctgttaaaac tagaattttt aaaggaaaac gatttttcag atatgctagc tgtctatgct
     8401 aattcggtaa aattatatac agacacgaaa acaataagag aatattttgg tatcgaatac
     8461 agtagtaact tgggagatgt tttatttcaa tttagccaaa ctcttgctcg atttattccg
     8521 acagaagtta gtgagaagaa aaatgaagac caaaaagaag ccatgtgttt ctcattaagt
     8581 caaagtgatt cagaagatcc cagaaaaaaa tattgttttt cagttagaag aaatccttta
     8641 aagggaaatg gtgagctggg aaaacgaagt ccttttaatg acaataaaac gagattgtat
     8701 agacccagct tatatgaacg attagggtca gataccaatt taagtttcag atattcaatg
     8761 aatccagatg atgaagaaac tgatgaaggt attattgcaa aatggacaaa aaataaaatt
     8821 gaatagttaa agcattgaaa gagcaatcac ctattttgat tgttcttttt ctatttttac
     8881 ggaaaggacg tgaagacatg aaaaaaataa gaagttacac cagtatttgg tcagtagaaa
     8941 aagtgattta tgcgattaat gatttacaac tccctttccc aattaccttt acgcaaatga
     9001 catggtttat cgtttctttg tttgtcgtca tactctttgg cagtttacca ccactttctc
     9061 tgattgacgg agcactactc aaatacttag ggattcccat tgttctcact gggttcatgt
     9121 gccaaaagac ctttgacgga aagaaaccct atggatttct aaagtctatc attacctatg
     9181 ctctacgccc taaagtaacc tacgctggca aacaaatacg attaaaaaaa gaaacaatga
     9241 atgaatcgat tacgattgta aggagtgaac aactagatgg catatccgat taaatatatg
     9301 gaagataatc tcgtatttaa tcatgatggc gaagtattcg cttattatga attaattccc
     9361 tataattaca gttttttaag ttccgatgaa aaaattcaag ttcatgataa tttctgtcaa
     9421 ttgattgccc aaaatcgtga tggcaagatt catgctctgc aactagcaac cgaatcaagt
     9481 attcgagcca cacaggaaca atcgaaaaaa gaaatcactg gacgattaaa agagatagct
     9541 tacgaaaaaa tagatgaaca gaccgaagcg ttaatttcta tgattggtga caatcaagta
     9601 gactatcgct tttttattgg ttttaaactc tacctcaatg aacaggaagt atccgtaaaa
     9661 aatgttggga aagaaattca aaaagcattt gcggaattct ttcatggtgt gaatcacaaa
     9721 ttaatgggcg attttgtttc tatgcctatg gcggaaatcg aacgcttttc taagatggaa
     9781 cagttgttag aaagtaaatt atccagacgc tttcagattc gtaaattgga gaaagatgat
     9841 tttggttata ttattgaaca tctttacggg caaacaggtg tcccttttga tgactacgac
     9901 taccatttac cgaaacgata cgaagataaa aaagtgttgg taaagaaata cgatattctc
     9961 aaacccactc gctgtttaat cgaagaaaat caacgctatt tacggattga acaggaagat
    10021 accactactt atgtggcgta ttttacaatt aatagtattg ttggtgaatt ggatttccct
    10081 aatagtgaaa ttttttatta ccagcaacag cagtttactt tccccgttga taccagtatg
    10141 aatgttgaaa ttgtcgccaa taaaaaagcc ttatctaccg ttcgcaataa aaagaaagaa
    10201 ctgaaagatt tagatagcca cgcatgggaa agcgacaacg aaaccagtac taatgtggtg
    10261 gacgctttag aatctgtcga tgaattagaa agtaatttag accaaaccaa agaatctatg
    10321 tacaaactaa gctatgtggt acgggtatca gcaaagaatt tggacgagct gaaacaacgt
    10381 tgtgatgaag taaaagattt ttatgatgat ctgtctatca aattagtacg accttttggc
    10441 gatatgctag gcttgcataa tgaatttatt ccctcaagca agcgatatat caatgactat
    10501 attcaatatg tcacgtcgga ttttttggct ggtcttggtt tcggtgctac acaaatgatt
    10561 ggtgaaaatt ctggtattta cgtcggttac aatctcgata caggcagaaa tatttatctc
    10621 caacctagcc ttgcaagtca aggaattaaa ggctctgtaa caaatgcatt agcgtccgct
    10681 tttattggtt cattaggtgg cggaaaatca ttctctaaca atatgctggt ctattattca
    10741 gtactctttg gcggacaggc aaccattgtt gacccaaaag ctgaacgtgg tgaatggaaa
    10801 gaaaccttac ctgatattgc ccatgaaatc aatattgtta atctcacgag tgagaacgac
    10861 aataaagggt tacttgaccc ttatgtgatt ttaaaactcc cgaaagattc agaaagcctt
    10921 gccattgata ttctcacgtt cttaacaggt atttccagcc gagatagcga gaagtttcct
    10981 gtcctgcgta aagctattcg gagtgtaact caaagcaaac aacgagggtt gttattggtg
    11041 attgatgaat tgcgaaaaga agatacgccc atcagcaata gtattgctga ccatatcgaa
    11101 agctttgtcg attatgattt tgcccatctg ttattcagtg atggcagtgt cacccaatcc
    11161 attagcttgg aaaaacaact caatattatt caagtggcag atttggtctt acccgattcc
    11221 aatagctctt ttgaagaata cactaccatg gaattattaa gtgtggcaat gctgattgtc
    11281 attagtacct ttgctttaga ctttatccac tctgaccgtt ccatttttaa aattgttgac
    11341 cttgatgagg cttggagttt tttacaagtg gcacaaggaa aagctctatc tatgcgattg
    11401 gttcgagcag gacgtgccat gaatgcaggg gtctatttcg ttactcaaaa cgcggacgat
    11461 ttactagatg aaaagatgaa gaataatatt ggcttgaaat ttgcctttcg ttccactgac
    11521 ctagtggaaa tcaaaaagac cttagaattt tttggtgtgg acaaggaaga tgaaaacaat
    11581 cagaaacgct tacgtgaatt agaaaatgga caatgtttag tttcagacat ctatggtcgt
    11641 gtaggggtta tgcagtttca cccgattttt gaagagttgc ttcatgcctt tgataccaga
    11701 ccgcctgtgc gaaatgaggt ggaagaatga cacaaaaaca aaagaaattt cttcactata
    11761 gttggataac gctcctttgt gtgggcgtta ttttactttt attaggcacg ctgggcaatg
    11821 cagtacaagc gacaggctta gttgatgaaa ccattgatac aagcaatgaa tactccaagt
    11881 atggtttgaa tcaatatcag cttgattatt atgtggacaa tagctggggc tggcttccat
    11941 ggaattggag tgatggcata ggacaatcgg tgatgtatgg attgtatgcc attactaatt
    12001 ttatttggac aatttctctt tatctatcga acgccacagg ttatttggtg aaagaagcct
    12061 atgccttaga tttcattagt caaacatccc aagcaattgg cgaaaacatg cagacgattg
    12121 caggcattac accgaatggc ttttccagtt cagggtttta tgtcggtttc ctccttcttt
    12181 ttattctcat tgttggaatc tatgttgcct atacaggatt ggttaagcga gaaacgacga
    12241 aagtgatacg agctgtttta aactttgtcg tggtgtttat tctatcggct tcctttattg
    12301 cgtatgcacc cgattatatt gcgaaaatca atgatttttc caaagatgtc agtaccgcca
    12361 gtctgaatat tgggacaaaa attgttcttc ctaacacgga tagtcaaggg aaagacagtg
    12421 tggacatgat acgtgacagc ttattctctg ttcaagtaaa gcaaccatgg ctattgcttc
    12481 aatatggctc cactgatgta gaagcgttag gggaagaacg tgtggaaagt ttattgtcta
    12541 ccagtccaga tacaaacaat ggtgaagata gagaaaatgt agtgattgaa gaaattgaag
    12601 atcatgacaa tacctattta accctaccga agacgatttc cagattagga acagtcttct
    12661 ttttgtttgt attcaatatt ggtatctcga tttttgtttt ccttctaaca ggaatcatga
    12721 ttttttcgca agtgctattt attattttcg ctatgttttt gccaatcagt ttcctattaa
    12781 gtatgttgcc gagttttgat ggcatgggca ggcatgccat taccaagtta tttaatgtga
    12841 ttatgacaag ggctggtatt accttgatta ttaccgttgc ctttagtatt tccactatgc
    12901 tttattcgct gtcagcaagt tctccctttt tcatgattat gtttttacaa attgtgacct
    12961 ttgcagggat ttattttaaa ctgggcgatt taatgagcct attcacttta caaagcaacg
    13021 actctcaaaa catgggcaga caagtgtttc gcagacctcg tcaaatgatg aatcgacaaa
    13081 ccagaagatt tcaacgcagt atgagtaaga tttttcgtgg aaaagcaggg tcaacgaagc
    13141 aaaagacaat gacaacaaag cagaatcaaa ccaataaagc taaccatact cgtcaaaatg
    13201 aacggactac accaaagaaa gaaacagcac tttccaatgt gaaaaagcaa caaggcggta
    13261 tcgggcaacg attaggtgaa aagacagccc atgtattgga cacgaaaaat cgtctagtca
    13321 ataaaagaaa gcaggcaaaa caacagatac aggcgacacc aacccatgtc aaatatgccc
    13381 ttcatcaagg aaaagagaat gtcactcata atgtaacaga ctttaaacaa tctatggcag
    13441 ataccaaagc tcaacgcaaa caacagcgta tgaaccagca ggagcaaaaa cgaaagaaca
    13501 ttgctcaaaa gcgtttggag ctggataaag caaaagaaaa aagacgaaaa gaaaacccat
    13561 catctcctgt tcagaataac cagcagcatg ttcgcaagcg tcagcaaacc gtcacgcctg
    13621 ttttgtcaca aaacactaaa cgtgaaaatc atcagcgacc attgaaaaaa gagcaaaaac
    13681 aaaagacacc accgaagcaa ttcaatcaga ggaagctaaa taaaagaacg gataagcgag
    13741 gacaacaaac atgaagctaa aaataacagt gatttgtagt gtggtcttct ctctcttctt
    13801 ttttctctta ttattcctag tcattttctt tgcagatgat acggacagtg gcgaaaacaa
    13861 caaggattct tctattccac aaggcggtgt gaccgtttca ccagaagtgt tggcacaccg
    13921 tccgttgatt gaaaaatatg gtaaggaata tgggattgaa gactatgttt cttatatctt
    13981 agccattatg caagtggaat cgggcggtac agcagaagat gttatgcaaa gttccgaatc
    14041 tttgggttta ccgcccaaca gtttgagtac cgaagagtcc atcaaacaag gggttaaata
    14101 tttcagtgaa ttattaacca gtgcagaaca acaaggagtg gatatagatt ctgttatcca
    14161 atcttataat tatggcggtg gctttttaaa ttatgtgagg agtcatggga aaaaatatac
    14221 ctatgaatta gccgaacagt tttctaaaga gaagtcgggt ggtcaaaaag cagactatcc
    14281 caatcctata gccatacctg tgaatggtgg ttggcgatat aactatggaa atcagtttta
    14341 tgttcagttg gtttcacaat acctaaccga cacttcccca acagaatttg atgatgaaac
    14401 cgtgcaagtc attatggacg aagccttgaa atacgaaggg tttccctatg tctttggagg
    14461 ggcgtcgcct accacctctt ttgattgtag tggcttaata caatgggtgt atgacaaagc
    14521 tggcatttct ctccctcgtg tcgcccaaga tcagtatgac gctacgcaag aaatctctat
    14581 ggaagaagcc caagcaggcg accttatctt ctttcattca acctataatg caggcacata
    14641 tgtgactcat gtggcgatat atttagaggg aaatcgcttt tatcatgcag gcgacccaat
    14701 cggttatggc gacttaagca gtcgttattg gcaagaccat ctgattgggg ctagacgtgt
    14761 tattcataac taagaaagga atgaatcaaa tgattataaa aatcgagcga aaagaaaaga
    14821 aggagaaacc aaagaaatct aaaaaaccga gcaagcaaag aaaagttccg atgattaaag
    14881 ttggcacgca taagaaatta acctttgttt tatgggtttt attgattggt agtgtcggat
    14941 ttggaatcta taaaaatttt actgccattg acactcatac tgtccgtgaa acagaaatca
    15001 ttaaacagca gattgtcgat accaaccaag tagaaagttt tgtgaaatcc tttgcgaaag
    15061 actacttttc gtggcaacaa tcccaagaag ccattgataa acgaaatgaa aaattgaccc
    15121 attatttgac ggaagaattg caggtattaa atgaagaaat gattcgtaag gatattccta
    15181 ctagttctag tgtgaacgat atacaggtgt ggcaggtttc tcaagtgaat gagaacacct
    15241 ttgaggtact gttttctgtt gaacaagtta ttaccgaaga caaagacaag gaaactatat
    15301 cgtctagctt tcatgtggtt gtccatatag atgaatcaga taatatggtt attatcaaaa
    15361 atccgacaat gagtaagaaa cctcaaaaat cggactacca acccaaacag ctagaaagtg
    15421 accatacagt agatacagaa acgatggacg aaatcactag ctttttagaa acgttcttcc
    15481 agctctatcc taccgccaca gaaaaagaat tgacttacta tgtaagtaat catgtgttac
    15541 ctatgattaa caaggaatat gttttcgagg aattggtgaa tcctatcttt accagaaaag
    15601 ataaccaagt aatcgtgaat gtcgctgtga aatatttaga tcaagaaaca aaggcaaccc
    15661 aaatctcgca atttgagttg atattagaaa aacaagataa ttggaagatt gtaaaataac
    15721 aaatattggt acatgattac agatactttg taatcatgta ctctttttga taaaaaattg
    15781 gagattcctt tacaaatatg ctcttacgtg ctattattta agtgactatt taaaaggagt
    15841 taataaatat gcggcaaggt attcttaaat aaactgtcaa tttgatagcg ggaacaaata
    15901 attagatgtc cttttttagg agggcttagt tttttgtacc cagtttaaga atacctttat
    15961 catgtgattc taaagtatcc agagaatatc tgtatgcttt gtatacctat ggttatgcat
    16021 aaaaatccca gtgataaaag tatttatcac tgggattttt atgccctttt gggtttttga
    16081 atggaggaaa atcacatgaa aattattaat attggagttt tagctcatgt tgatgc
//
LOCUS       DACDLM010000063        15048 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.065, whole genome shotgun sequence.
ACCESSION   DACDLM010000063 DACDLM010000000
VERSION     DACDLM010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15048
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.065"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(21..251)
                     /locus_tag="IV356_002140"
     CDS             complement(21..251)
                     /locus_tag="IV356_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015806.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            complement(687..1253)
                     /locus_tag="IV356_002141"
     CDS             complement(687..1253)
                     /locus_tag="IV356_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAP9015807.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1253..2209)
                     /locus_tag="IV356_002142"
     CDS             complement(1253..2209)
                     /locus_tag="IV356_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HAP9015808.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2209..2865)
                     /locus_tag="IV356_002143"
     CDS             complement(2209..2865)
                     /locus_tag="IV356_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAP9015809.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3235..5253
                     /locus_tag="IV356_002144"
     CDS             3235..5253
                     /locus_tag="IV356_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP9015810.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     gene            5680..8094
                     /locus_tag="IV356_002145"
     CDS             5680..8094
                     /locus_tag="IV356_002145"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016183651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HAP9015811.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8442..9995
                     /locus_tag="IV356_002146"
     CDS             8442..9995
                     /locus_tag="IV356_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAP9015812.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10376..12160)
                     /locus_tag="IV356_002147"
     CDS             complement(10376..12160)
                     /locus_tag="IV356_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9015813.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12175..13896)
                     /locus_tag="IV356_002148"
     CDS             complement(12175..13896)
                     /locus_tag="IV356_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9015814.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13996..14757
                     /locus_tag="IV356_002149"
     CDS             13996..14757
                     /locus_tag="IV356_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP9015815.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         4884 a         2766 c         2969 g         4429 t
ORIGIN      
        1 ctcattaaaa agcataacca ttactccgat ctgtttttaa aattagtttc tacctctaat
       61 atatatcgag tttttatttt gccttcagag aatactgttt ctttttttgc agttacaggt
      121 tgtttatttt cggaaaaagc taatatagct aagattgaaa catccatctg gaatttatct
      181 tttttactgc tttgatcata aaagtctgca tattcatcac tgatattttt tctaataaat
      241 tcttccatca taaaaatcac ctcaaaacga ttatacgaac ttacgttctt gttgtaaagc
      301 gatatttgag gggcaaaaaa ggggcataat ttgactgata ttaagttagc tattgatata
      361 tgaatgacat acaaaaatat aaaatctttt aaaaatgctt atatatcaat gtttttgcca
      421 ttcttttata tatctgttat atgtcaaaaa aatgtgttca atttcaattt gtatttgaat
      481 aaagaggttg tgaaaaagct gtcctgcatc aagtaataag aacagccaat caaaaacagc
      541 ttctcatgtt tttgatttgg ttggacttat taccgcagat ataagctttt gagcaccgtg
      601 aataaagagg ttatgaaatc aacgctctaa cctgagtatt agagaaaaaa acgcaaaaca
      661 tatcatttat gttttgcgtt ttttatttat ctttttttct caatacaata taaaataggc
      721 ggctggttct tttggttgat aaaccgataa ttcagcacat tatatgtttc ctgtggcagt
      781 ttggaacaaa aagaatcaac catatccagt tctttttctc caccttcatg accatagtag
      841 acgacaagga tcaatcgtcc gcgaggcaca agtcgtttca atatttcttc catagctgtg
      901 cgtgtagtct ctggcatagt gatgattgct ttatcacttt ttgggagata ccctagattg
      961 aaaatccctg ctttgagatt ttgttgttca gctatcactt ctcctaacgt ttcgtggcct
     1021 tgtagaaaca atgagacacg ttcttctaac tgacgctgtt ctagcctttc acgagtagca
     1081 tcgattgctt gttgctggat atcaaaacta tagacatgac cagtttttcc gatgtgttct
     1141 gctagaaaaa ccgtatcgtg gccattgccc atcgttgcat ctacgacgtg atcccctggt
     1201 tgcaagattt cttgcagtaa tgtatggctg aaatgcaaag cagtttgcaa catcagacgc
     1261 tcaccttttt ccgtacatca tattttcctt ggaagctatc tctgcgaaga agttcttcat
     1321 caattgcatt caagacttcc cattttttca agctccacat tggtccaatc aaggaatccc
     1381 acggcgcatc ccctgtcaaa cgatggatga tgatctcttt tggtatcatt tccagctggt
     1441 cgcaaatgac attgacatag tcaggacggc tcattaattg aaggcgacct tcatgatagt
     1501 cccgcaacat tctcgttttg cgcatcagat gcatcaaatg gagcttgatt ccttggatat
     1561 ctgaatctaa aatggtgcgt ctgacatttt ctttcatcat ttctaaactt tcgcctggta
     1621 atccgttgat caaatgcgta caaacacgga tattatgttt gcgtaattta gccacgccat
     1681 ctaaataagt ttgataatca tgtgctcggt tgatcagttt tgaagtttct tcaaaagttg
     1741 tttgcaatcc aagttctacc cataaataca tccgctcgtt cagttcagca aggtaatcaa
     1801 ctacttcatc tggcagacaa tccggtcgtg taccgactga taatcctacg acacctggta
     1861 aattgactac ttgctcaaat cgttctttga ttatttcaac tggcgcatgg gtgtttgtaa
     1921 aattttggaa ataaacgatg tattgttgga catgaggcca tttttgatgc atcatgtcga
     1981 tttctttctg gaattggatt ggaagagggt cttcaggtgc aacgatcatg tctcccgaac
     2041 cagatacact gcaaaaagta caaccgccat gggcaacagt cccatctcga ttcggacagt
     2101 caaatcctcc atcgatcggc accttgaaaa ttttcccgcc aaactcattt cgtaaagcgt
     2161 aattccaaga atgatatctt ttatttcctt ctgaataagg aaaagtcatt aaaagtcctt
     2221 ctttctgtaa gagttatcta tttgttttct tttttctcta tacactggat aagtcaggca
     2281 cagccaagaa agactgagta agtagccgcc gatgatatca gtaggaaaat gaacgcccag
     2341 ataaatgcgg cttatcccga cacttactat aataaacatc atcagcaatt gaagcaatgt
     2401 gcgtaaggtt cttttttgaa caaaagctgg aagcagaaat agtaaagaac cgtaaagaat
     2461 catactgcct gctgcatgtc cactagggaa actgtaactt gtttcaacta ctaagtgcgc
     2521 caatgaagga cgctctcgca tgaaaaatag tttgatcacc gggttgatga ttccagcaat
     2581 tacaataaat ccagaaacga accaaaatgt ttctgccctt tttttcttat accacatcca
     2641 taaagccgca caagcaaata aaatgatgac ggtaagagga ttaccgaatt tagtcataaa
     2701 gagttggtag ctgttcagat caggataaga agctctgaca atgcctgtaa accactgatc
     2761 gaaaccagaa agccacgaca gatggaactt tacgatccag cccaaaatga aaaacaggac
     2821 aagaaagaag ctaccagcca cctgaaatga tgttttatat ttcatacaat tcctcctttg
     2881 aagcaatgac ttattatagc atttttggtc cagcgaaaaa aacggtaaag agataaaacc
     2941 aatgtatgat tcctctttga ataaccaata ttcttataaa aaaaataact gtaatcggaa
     3001 agacattttt tggtaatgca aatgaaatgt tagggaaata aaatcagtgt ttttcgaaat
     3061 ccttttaaac aagaacgtag acgtaggaag aacttgaaaa tgaacagaag ttgttcatta
     3121 cggtaaatta caatatgatt acaaaaaaca acaaagctct taaataactt ttaataaata
     3181 ttaagagaag ttataattat taataataga taaattgaag ttggaggata gaagatggaa
     3241 aacattgcaa gaaaagaacg gagacgttta gaacagacca aacgttttcg aaaagcaaaa
     3301 cgaggggcag caatcgtggg aactgcgatg gtaggctgtt ctgtcgctgc cccattagta
     3361 cagccggttc ctgttcaagc ggatgaaaca cctgttcagt tcggcgcaag aatcaataca
     3421 gcggcattta tcacagaaat tgctacttat gctcaaccaa tcgctcaagc caacgatcta
     3481 tatgcatcag tgatgatcgc acaagcagtt gtagaaagcg gttggggcag tagtgcgtta
     3541 tctcaagcac cttattataa tctttttggg ataaaaggca gctatcaagg acaaaccgtc
     3601 tacatggata cgcttgaatt tttaaataat caatgggtaa ataaaaagga gcctttccga
     3661 caatatcctt cttttgctga atctttcaat gacaatgcct atgtacttag aaatacttca
     3721 tttggcaacg gttattacta tgccggtact tggaagagca acacgaaatc ctatacagat
     3781 gcgacagctt gtttgacagg gcgttatgcg actgatcctg gttacgcagg caaattaaat
     3841 aatatcatcg caacttacgg attgacccaa tatgatacac cagctagcgg aaacgcaggc
     3901 ggtggagcga ctacaggtgg caataatact ggaagtgcag gtagtactgg cggttcaagc
     3961 aattctggta atacaaactc aggttcagca acttcgacca cttatactgt ccaatctggt
     4021 gattctgttt ggggaatctc aaataaattc ggtatcacaa tggatcaatt gatccaatgg
     4081 aacaacatcc aaaacaattt catttatcca ggacaaaaac tgacaatcaa aggtagccag
     4141 gaaaatggct cttcgacgaa taattccggt aacaatacca actcttcagg aaatgctggt
     4201 acatcaaacg gaggacaaac aactggtgcg aaatacactg ttcaatctgg tgattctgtt
     4261 tggaagatct caaatgatca cggaattacg atggctcaat tgattgaatg gaacaatatc
     4321 aagaacaatt tcgtttatcc aggacaacag ctaatcgtat caaatggcgg ttcttctaat
     4381 gctggagcaa atactggctc aaatactggg aatacaagtg gctctagttc gtccagctca
     4441 agttcttcta atacagcttc aggaacgaaa tatacagtta aagccggaga ctctgtttgg
     4501 agcgtctcaa ataaatacgg aattacgatg gctcagctaa tccaatggaa caatatccaa
     4561 aataacttta tctacccagg acaacaactg actgtttcaa acagtggatc aacaaacagc
     4621 acgtcaggta atacaggttc gtcaaccaat acaaataaca gcagttcagt taatactggc
     4681 agcagttcgt ctcaaggcac ttataccgtg aaagcaggtg aatctgtttg gagcgtggca
     4741 aataaaaacg gcatcacgat ggatcagtta atcgaatgga ataatatcaa aaacaacttc
     4801 atttatccag gacagcaatt gatcgttaaa ggtggaactt cggcaaatac aaatacaggt
     4861 tcaactactt ctgcagcgaa accaaataca ccgaatacgt ctgctacgac aagtacatca
     4921 tccactggta atacgatgta taccgtgaaa gcgggcgagt cagtttggag cgtagcgaac
     4981 aaacatcata tcacgatgga tcagttaatc gaatggaata atatcaaaaa taatttcatc
     5041 tatccaggac agcaagtgat tgtgaagaaa ggttcatctc aatcaacaaa ccaacaatca
     5101 gttactggtt cgaaaaccta tactgtgaaa tctggagaat ctgtttggag tgttgctgac
     5161 agtcatggaa ttacaatggc tcaactaatc gaatggaaca atattaagaa caactttatt
     5221 tatccaggtc aaacgttgat tgtagctaaa taaaatagct gttcgaagaa ataacgattg
     5281 aattccacaa aaatatttgt tactataagg ctacttaaat atgacaacac ttgaaaagga
     5341 agtagtaaaa agactgaagt ttcagagagc gcatggctgg tgagaatgtg cacggatgct
     5401 tttgaactcg cctttgagtt gcccttgctg aatacccgag taagcaagcg gcggtgacgg
     5461 ccgttacaac gttcgaggcc ttttcactaa ggtaaaatta ggtggtaccg cgtagattac
     5521 gtcctataaa aagagcaatc tttttatagg atttttttat ttcttttgtg aagtttgaga
     5581 aaacaaagca aaaggaaata aaaataaaca gattctgccg gttttttcgt tatatttata
     5641 atagaaacaa gtgttttcaa tagaacagga ggacagcaaa tgagttacaa tcataaagaa
     5701 attgagaaaa aatggcaaaa atactgggca aaaacgaata ctttcaacac ccatgatgat
     5761 cctgaaaagc caaaatttta cgcactggat atgtttccct atccatccgg tcaagggcta
     5821 catgtagggc atcctgaagg ttatacggca acggatatcc tttcacgtgt gaaaagaagt
     5881 caaggataca acgtgctgca tccaatgggg tgggatgcat tcggtctgcc tgctgaacaa
     5941 tatgcgctag atacaggaaa cgatccagct gagtttaccc aaaaaaatat cgaaacattc
     6001 cgacgccaaa tcaattcttt aggatttagt tatgactgga atcgcgaagt gaatacaact
     6061 gatccggagt attataaatg gacacaatgg atctttacga agctttatga aaaaggtcta
     6121 gcttatgaag cagaagtagc ggtaaactgg gtacctgaat taggaacagt tatttcaaat
     6181 gaagaagtga tcgatgggaa aagtgaacgt ggtggctatg atgtagtcag aaaaccaatg
     6241 cgccaatgga tgctgaaaat cactgcttat gctgatcgct tattggatga tctagaatta
     6301 gttgattggc cagaaagcat taaagaaatg caaagaaatt ggatcggtcg ttcagtagga
     6361 gcaaatattg aatttaaagt ggctggtacg gataaatcct ataccgtatt tacgacacga
     6421 ccagatactc tattcggtgc aacttactcg gttcttgcac ctgaactaga tcttgttaga
     6481 gaaattacga cccctgaaca aaaagctgct gtagaagctt atatcgaaga gacagctaaa
     6541 aaatcagatc taaagagaac ggatcttgca aaagaaaaaa caggagtatt tactggtgct
     6601 tatgcaatca atccagttaa tggcaaggaa atcccaatct ggatcgccga ttatgtatta
     6661 tcttcatacg gcacaggagc catcatggct gttccagcac atgatgaacg tgactttgaa
     6721 ttcgctcaaa ctttcggact agaaattctt ccagttatcg aaggtggaga tgttgaaaaa
     6781 gctgcttaca cagaagatgg tacgcacatc aactctgaat ttctagacgg catgaacaaa
     6841 caagaagcaa tcgataaaat gaatgaatgg ctagaagaaa atggcgtagg gaaaaaagaa
     6901 gtcagctatc gcttacgtga ctggctattc tcccgtcaac gttactgggg tgaaccaatc
     6961 ccaatcatcc attgggagga cggaacagtc acagctgtcc cagaagaaga gctaccatta
     7021 cggttgccta agacaaaaaa catcaagcca agcggtactg gagaatctcc attagcaaat
     7081 atcgaggagt gggtcaatgt cgttgatcct gtaacaggta aaaaaggccg tcgcgaaacg
     7141 aatacaatgc cacaatgggc aggaagctca tggtattacc tgcgttatat cgaccctcat
     7201 aacaaaaaag aactagcaga ttatgaaaag ttgaagcgtt ggctaccagt tgacatctac
     7261 attggtggag cagaacatgc ggtacttcat ttactatatg cacgattctg gcataaattc
     7321 ttatacgata tcggtgttgt tcctacaaaa gaaccattcc aaaaactata caatcaagga
     7381 atgatcttag gcgaaaacaa cgaaaaaatg tcaaaatctc gtggtaatgt agtcaatcct
     7441 gatgatgtgg tcgaaactta cggtgcagat acactgcgca tgtacgaaat gttcatgggg
     7501 ccattagatg cttcgattgc ttggagcgaa aatggcttag aaggaagccg taaattcttg
     7561 gatcgtgtat ggcgtttgat cgttgatgag aacaataaaa tgcgtgaccg tatcactaca
     7621 ttgaatgatg gcaagcttga taaagtgtat catcaaacag tgaaaaaagt gacagaagac
     7681 tatgaaaatc ttcatttcaa tacagcaatc tcccaattga tggtctttat caatgaagcc
     7741 tataaagtgg acgctctgcc ttatgaatat atcgaaggat ttgttcaact actcgcaccg
     7801 attgctcctc acatgggtga agaactatgg gcaatccttg gaaatgatgg tggtatttct
     7861 tacgcaccat ggccaacata cgatgaagca gcacttgttg aagacgaagt agaagttgtt
     7921 ttccaagtaa acggtaaagt tcgtgcgaaa agcaatgttc cccgagactt aggaaaagat
     7981 gagctagaaa aagcagcatt agccaatgaa atagtgcaag aatatattga aggcaaaaca
     8041 gtcagaaaag ttattgcggt accaaacaag ttagtcaata tcgttgctaa ttaattggct
     8101 ctttgtcaat aaggactgat gagttgtgca aaatcaaatc tgggccagaa tgaacttcat
     8161 tctgtctcag attttttgtt atttcaaatt gattaattga ttgatcaaaa aggttttgat
     8221 tttcatgttc tcaaacacgt tcaatgtctt tttcttctga atggtcttgt aagagatctc
     8281 tgtaatcatc aaatttttgt ctattaatct tagtattttt tgatgtataa actacctgaa
     8341 attgagagta cataccaaat tcataaattt tttattagtg ggactagtga ttgtatggat
     8401 tttgacgcat aatgaatgaa gtatgagaaa aggagagaca aatggatcaa gaactattta
     8461 ttatcgaagt attatcagct aaacaaaaaa ttatcgagaa agcgaaaaaa agagcgaaaa
     8521 gaataatgtt caagctttta agcttagtat ttttctctgg tttgcttttt ttcggagctg
     8581 tatcgttcct atatcgccat atgagtgcag tagtccgttc agctgaaggg atgcaaaaat
     8641 taaataattt gtatcacttt tcgtggggag ttggcggaat aacaattgtt gtgcttattg
     8701 tttttcttct acttatttgg ctccgttacc atcaattgtc gcgtcatttc gatcaatggc
     8761 ttagtcaaag agcacaacag tttttacata ataaaccaac ttctcaagat gatgactatc
     8821 tttattttga gaagacttcg acgagtcaag cttttcggat acaaaaaagt gattgccagt
     8881 tattgctgag atcacttgat gatttaccta tctacttagg cgaaagcaaa tcaaaattcg
     8941 gaatgaacac attccatatt tttttactag aaaacgaacc cagatgggaa aaaagccagt
     9001 cttcgcctgg tggatacctg acaactaaga tgagtacatt agtcactggt tttttcctca
     9061 ttcttttagc tggaacaatc tattatggga gatacactca gccaaaaatg tcttctcata
     9121 taaatgctgc ttctcacatg acaatgaact caactaacga tacgcatata caaaagacaa
     9181 atgaagggtt gttagctgat cctaagcaaa aggtaaattt gacaacacaa aagataaatg
     9241 atctcaaact tgatacagag acgcactctc tctatatgac aacagatagt ggtgctaatt
     9301 gggtatttgt gccgattgat tcgcaatggt tgcgttttgg cgaatacacc ctgacaacgg
     9361 ggctgattcc tgaaggttat tggatggaca acacatatga tatttccgcc gatttctcat
     9421 ggtttatcta ttcttctggg gatgatgtac gtctgctgac ttcaagagat aatggtaaaa
     9481 catggcaaac gtctattatc acccaatcag ttcagccgat acgttatcga aaagcggtat
     9541 tttatggcaa cgatggtcta tttatctgta catcagccag tgggatgtct gcagaaactt
     9601 tgtacattta cactactatg gatggcggaa tcacttggat aaaaagtgga agtacaatga
     9661 tcaatcagcc agtacaaaat gtcagcttcg ttacaacttc tttaggtttt gtttcgacac
     9721 gtgaaagttt gttttataca aacaacggag gacgctcatt caaagaatca gttctgtcga
     9781 ttccggaaaa ctatcagaca ggggggatag atctttttca atcaccaaat gaagttactc
     9841 aaataagcgc gaatacgtta gagacaaaat tttatttgtt gaaaaaagga ccaatcgatg
     9901 cagggaaaat gtttgcctgc ctcttccgtt caactgataa cggggaaaca tggcaattcg
     9961 ttcagcaact atcgcaagta gaacaaggag attaaagaag agagattgtg agcctgacgt
    10021 tcagcaccga gtcacaagaa acaaattcaa aaaacagctt ctcatatttg ttgaatagtg
    10081 taactcgtga ttcggagttg acaagagcaa caagaagcga ttttgaagta tagcttctcg
    10141 tattttacaa gatcgtgtct tattgccgat aggttgtctc ttgaacaccg tttattcgta
    10201 aaaagggatt gtgacaagtc ttttgtcact acttaccgaa cgaaactgaa ggagctatcc
    10261 aaaaagtatc attagtatta ttctttgtgt ttctagtggc accactagta catttaaaaa
    10321 agctatcgat catggactaa tcatacatga tcgatagctt tttagataat gtttgttacg
    10381 ctatctgaaa ttgactatta taaagactgg cataaagcgt tggtgattgg agtagttcag
    10441 aatgtgttcc tttttcgacg atatcgccat tcttcattac aaggatcatg tctgcatttt
    10501 caatcgttga caaacggtgt gcaatcacaa aacttgtcct atcttttgtc acagcttcca
    10561 ttgcttgctg aatcaatgct tctgttcgtg tatctacgct agaagttgct tcatctaaaa
    10621 taacgacagg aggattcgct agaatgactc gagcaattgt caataattgt tgctgtcctt
    10681 gagataacgt gccgttttcg ctagaaatga tcgtatcata tccgtctggc agtgttcgaa
    10741 taaagtgatc acattgtgcg atttcagccg cttcgataat ttgttctctt gtggcatcca
    10801 ttttcccgta ggcgatatta tcagctaccg ttccttcaaa cagccaggta ttttgtaaaa
    10861 ccatcccaaa agaacgacgt agttctccac gtgaaagctt ggtaatatca agaccgtcga
    10921 attcgatctt tcctttattc agttcataaa aacgcatcag cagattgact aaagtcgttt
    10981 ttcctgcacc agttggacca acgatcgcta ccgtttgttt tggctttact gaaaaatcga
    11041 cttgattcat caatatttta tctgatgtgt aaccaaactg tacatttttg aaagctattt
    11101 ttcctttcgg ttgttctaaa agtcttgcat ctggaaggtc tggaatttca tctgtttcat
    11161 ctaatatctc aaatatccta tcgattgctg ccattgcgga ttggatcgag ttgatcacat
    11221 aagaagcggt agaaattggt tcagaaatct gattgatgta ctgaagataa gcttgtaaga
    11281 agccgatcgt cacaccacct gatagaacaa gcatagcacc gaataccgca cttatgatga
    11341 aggcgagttg attaatgaaa cgaatggccg gatagatagc acagttcata aattgagcac
    11401 gtttaaaagc gttgtattgc tttttattta cttcgtgtat agcagcttct gcatgagctt
    11461 gctgattgaa tgttttgacc actagattac cagctaagat ttcttccatt cgattattta
    11521 aaacacccag ttcatactga ttctgttcag aaatctgttt gtttttgttc gcaatcttag
    11581 ttgtaacaat tgaactgcca acgatcagca ataagacgag caaagtaagc ttgctttcga
    11641 tataaaacag catcagacca gcagcagcta ttgttacgac agaagtaaaa aattgattga
    11701 tacctgtcaa taacacttga gaaagttgat tgagaccggt agttgtccga ctaatgatgt
    11761 cacctacttg atgattgtca aaaaacgaca tcggtaatgt tttgaatttt tttgtgattt
    11821 cttttcgcac cctcaatgtg atcttttcgc ttaacgctgc cattgtccgt tcctgaataa
    11881 atgaagtgat gctgcttaag actgaacagc cgatcagcaa taagacaggg aacaacaatg
    11941 cttgtttgat atcactgaaa gaaagctgtc caatacctgt ttttcttatt tctgataaga
    12001 gatcatcgat cccgattccc atgatcaagg gcatggctac gactaatagg ttcccgaata
    12061 aactgcatag aaacaatccg taaaaatatt tatgttcagg tttgatcatt ttccaaaaac
    12121 gtatcaaagc acgcgtgttc aacgtttttt tcttttccat cgtatccctt ctttctatat
    12181 tccttgtgat tttgcaaact cctgataagt ttggcaatta gacagtagtt cttcatgagt
    12241 accttgtcca acgatttttc cttcatctaa aacaatgatg ttatctgctt gttggattgt
    12301 actgaggcgt tgagcaacaa tcacgagagt tttctccgac atgtgtttat gaagggctgc
    12361 tcttaatgct gcatctgttt tatagtctaa agcggagaaa ctatcatcga atacatagat
    12421 ctctgctggt ttgatcaacg ctcgagcaat acatatccgc tgtttctggc cccctgaata
    12481 attagaaccg ccttgagcaa caaagctgtc caatccgtca ggaagggtgt ccactagttc
    12541 ttctaattga gcgatcttga tcgctttaga caactcttct gttgaggcat attcatttcc
    12601 catctgcaag ttgcttaaaa ttgtcccgct gaataagaaa gccttctgag ggacataact
    12661 gatgtgggag cggatctgtt cttgagtcat ttgagtaaga ggaataccac caagggttac
    12721 ttttcctatc gtagggtcac taagtctcaa gagaagtttc gccaaactac tttttccaga
    12781 tccggtcccg ccaacgatcg ctgttgtttt tcctttaggt attgtgaaat caatatcttc
    12841 tagaactgga tcagagattt cagtatattt aaatgtgaca tgttcaaaag cagctgcatt
    12901 tgtctgatca aaggttggtt cagctactgt tttgatcgtc tcttcctcaa tttcgatctc
    12961 tgcttgcagt atttcttcta tccgtcgtaa tgaggcaaac gatttaggga taatgaccaa
    13021 taccatagct gcgatcatca agtaagcaag tgtcagcata gagtattcga ctacagcagt
    13081 cacgacaccg atttgtaatg ctccttctgc tacaagattt ccgccaaacc acaaaataga
    13141 agcataaacg attcccatga gcaaaaaagc aattggagtg acccaagcaa atattcggtt
    13201 cactttgatc atttgattag catagtcagc aaagctctta ttcgttcgct tttcttcata
    13261 tgattgatta tcaaaggcac ggatcatatt aatcccagta aagaattctc tcaatgtgat
    13321 ggtgatccga tccatttttg gctggatact caaagataaa ggtgcccctc gtttcatcag
    13381 tcgataaaca atccatacat aaaaaacaac agagatcaat gtaacccatg ttagtaatag
    13441 agaataacga aacatcatga gaatggtgaa aacgcaaata accggtgctg gtaagatcat
    13501 ttggcaaaat aaaacaatca tttgctggac attatcgaca tcattcgtca ttcttgtcaa
    13561 aagagatcca gaactaaaac gactgatatc cttcattgac agctgttgga atttacggaa
    13621 atatttctcc cgcgtttgga atccaaacct agcggaagcc aatgctgaaa agtaactaga
    13681 ggcaactgca gcgattgttc ctagaaacgc tacaagcagc atttcaactc caattttttt
    13741 tataactgag gcttcgccac ttgctatacc tgtgtcgatc agctttgcta ctaattttgg
    13801 tacacctaat gtaccggcga tttctaaaca gatcatcaca aaggtaagga gagcgagtcc
    13861 tttgtttttc tgtaagaatg tttttaagat agacatatta ttcctccttt tttcctgata
    13921 cttttcgatt ctataccttc aagtaacttg aaggtcaata gaaaaaagaa taaactgaaa
    13981 aagaggtgag aaaaaatgaa aaaaatgtat acgattggcc aagtatcgga actatttgat
    14041 ttgccaaaat caacgatccg ctattgggat gaacaaggat taatccgttc aagtagacaa
    14101 gaagagaatg attatcgatt gtttgatatc gatgatattt ttatgcttta tgatatcgtt
    14161 ttttatagaa aattagatat accgatcaaa cagatgaaga atttatatgg aaaaacattg
    14221 acggagttat atgagacact tgatgaaaca gaaagaagaa tccataaaga actggtggtg
    14281 atgaaacaaa aacaaaaaga gataagggag caaaaaaaac agttgaaatt gatgatcgat
    14341 acaaacgagg aagaatttcc tgtagaagag atcccttttg actgtatgat ctcaacggag
    14401 tttgaagata ttgtggaaat caaaaaattt ctacctaact attcaagctt tgggatgatg
    14461 agtatgccag cttccagttc acagacgatg tatggatttt ttatcgaccc tagtgaagta
    14521 catttattta ctcaagacgt gatttgggag aaaaaagata cggctgttta tcgtcgattc
    14581 ttattgaaat ccgagatgaa ccatgcggaa cgtaataata ttttagaaat cagagaaaga
    14641 atgtatgaaa aaggatggaa aacaggagaa gtgatcggcc agtatctatt gacgaatacg
    14701 gatgaaaaca atatcagaac tgaatattat catgcatgga tagaaatgaa aaaataggaa
    14761 atatgtgttt aagataactc gaaaatgatg gttgttttag ttataaagaa aaattttctg
    14821 gttcgattac gggtttaatg tgggggatta ttagtcgtgg atagatagaa ttttagtttt
    14881 ttagaggaaa tatgtcttta aaaatggaat ggttgcaatt cttagcgata tatacgatgt
    14941 aattgtcctc ttaaaaaagt atggaaaaat aattgtattg ggtgttatgt ataattcatg
    15001 gtgaactgag actaatgaga agaaaaattc atattgttat gagtgaga
//
LOCUS       DACDLM010000064        14454 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.066, whole genome shotgun sequence.
ACCESSION   DACDLM010000064 DACDLM010000000
VERSION     DACDLM010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14454
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.066"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..209)
                     /locus_tag="IV356_002150"
     CDS             complement(<1..209)
                     /locus_tag="IV356_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015816.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISS"
     gene            complement(197..826)
                     /locus_tag="IV356_002151"
     CDS             complement(197..826)
                     /locus_tag="IV356_002151"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HAP9015817.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            complement(833..1549)
                     /gene="pyrF"
                     /locus_tag="IV356_002152"
     CDS             complement(833..1549)
                     /gene="pyrF"
                     /locus_tag="IV356_002152"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HAP9015818.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKEIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            complement(1546..2478)
                     /locus_tag="IV356_002153"
     CDS             complement(1546..2478)
                     /locus_tag="IV356_002153"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HAP9015819.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDPDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(2475..3251)
                     /locus_tag="IV356_002154"
     CDS             complement(2475..3251)
                     /locus_tag="IV356_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HAP9015820.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(3305..6490)
                     /gene="carB"
                     /locus_tag="IV356_002155"
     CDS             complement(3305..6490)
                     /gene="carB"
                     /locus_tag="IV356_002155"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HAP9015821.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTYHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(6495..7571)
                     /gene="carA"
                     /locus_tag="IV356_002156"
     CDS             complement(6495..7571)
                     /gene="carA"
                     /locus_tag="IV356_002156"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010744830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HAP9015822.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(7576..8856)
                     /locus_tag="IV356_002157"
     CDS             complement(7576..8856)
                     /locus_tag="IV356_002157"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HAP9015823.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(8875..9801)
                     /locus_tag="IV356_002158"
     CDS             complement(8875..9801)
                     /locus_tag="IV356_002158"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HAP9015824.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(9814..11097)
                     /locus_tag="IV356_002159"
     CDS             complement(9814..11097)
                     /locus_tag="IV356_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HAP9015825.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(11111..11650)
                     /gene="pyrR"
                     /locus_tag="IV356_002160"
     CDS             complement(11111..11650)
                     /gene="pyrR"
                     /locus_tag="IV356_002160"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015694870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HAP9015826.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(11885..12796)
                     /locus_tag="IV356_002161"
     CDS             complement(11885..12796)
                     /locus_tag="IV356_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAP9015827.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKPAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(12793..13257)
                     /locus_tag="IV356_002162"
     CDS             complement(12793..13257)
                     /locus_tag="IV356_002162"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HAP9015828.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLVLAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICILIYIILDEKDQRKK"
     gene            complement(13262..13960)
                     /locus_tag="IV356_002163"
     CDS             complement(13262..13960)
                     /locus_tag="IV356_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAP9015829.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(13947..14333)
                     /locus_tag="IV356_002164"
     CDS             complement(13947..14333)
                     /locus_tag="IV356_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015830.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINDEKRSVLSHEKKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
BASE COUNT         3912 a         3313 c         2583 g         4646 t
ORIGIN      
        1 gaagagatta ttctcttctt tctgctaacc agtcttagaa aaatgaattt taaaaaaatc
       61 aaaaactgat cacgatagaa gtttcttttc atacctgatg aaaagatgct tctcgcaatc
      121 agtttttgga tttttgctat tccaattgat gattctggag acacaaatcg gatttctcta
      181 tcttcatcaa gcgcgcttaa atctgccaat tttcaggatc ttttttccat tcttttagca
      241 gagttaattc ttgctcatcg atataacgat cttctaaagc tgcttcaatc aatacagaat
      301 aattggtcaa cgtcataaga gggatttcgg ctttttcgaa atttgctttt ccttttggca
      361 actcatacgt aaagatagcc gcaacaccaa ggatatccgc accttctctt tttgctgctt
      421 cagctgcttc caagacactt ccgcctgtag aaatcaaatc ctcgatcaca accatcttct
      481 gaccttcaaa tatacgtcct tcgatttggt tacctttccc atgatctttc gccttacttc
      541 gaatatagac cattggcaaa tccagtattt ccgctaccca tgcggcatga gggattcctg
      601 ctgttgcagt tccagcaatc acttgtactt cagggtaagc ttctttgatt ttgcttgcta
      661 atccttttgc gatctctttt cggacttttg gatagctcat cgtgattcgg ttatcacagt
      721 aaattgggct tttgattcca cttgcccatg taaaaggatt acttggattt aaaaatactg
      781 cttcaatttc taataagtct tttgcgatac tttgttcaac attcatttta ggttagctcc
      841 attctgtttg aatcgtttga tatgctttat aaggattagt tgactgagtg attggtcgac
      901 ctataacgat aaaagttgag ccgatctctt ttgcctgaga aggtgtgact actcttgtct
      961 gatctcctgc gactgttcct tctggtctta tacccggagt taagcaaaca aattcgtctc
     1021 ctgccatttc tttgatcgct tctacttccc aagcagaaga aaccacacca tctaatcctg
     1081 cttttttggc acagctagca taatggatca cacttttttc taaagaaact tcgattagtt
     1141 gatcggcatg catttcttct tcacttgtag aagtaagctg agtgatagct agaagtagcg
     1201 gacgttttcc accttctgga gtcccctctt ctaatcctcg cattgccgcc tccatcatac
     1261 gaataccgcc agcggcatga acacaggtga gatcaacacc aagctttgcc aatccccgca
     1321 ttgctttttc gaccgtattc ggaatatcgt gaagtttcag atctaaaaat acattatgac
     1381 cagcctcttt tagataacgt acgatttcag gtccttcttg gtagaacaat tccattccga
     1441 ttttcacaaa caatttttct tctttcggga aaaatcgaag aaagtcttct acctcttgcc
     1501 tagttgaaaa atctaatgca ataattggtc gttggtctag ttgattcatc gttcacgttc
     1561 ctctctcact tcttttatta atctttccag cgattcgatg cctagttcgc tcattcgcac
     1621 agggagctct ttaattagtt taggacagat atacggatcg gtgaaattcg cggtccctat
     1681 agctacagca cttgctccag ccataaacat ctcaagaaca tcatccactg tctgcacgcc
     1741 gcccatccca atgattggaa ggctggatat acttgctact tggtgaatca aacgaatagc
     1801 gacaggcttg attgctggtc cggagagtcc acctgtttga ttggctaaaa tcggttttct
     1861 tgtcttaagg tcaatccgca taccaagaag agtattgatc atcgtaaacc catctgcccc
     1921 tccagcttcg attgcctgag cgattggaac gatgtctgtt acatttgggg acaatttgac
     1981 atagacagga acagaagaaa ctttctttac tgcttgtgtt aattgaaaag caacatcagg
     2041 atctgttcca aaagcaattc cgccatgttt gacatttggg caagaaatat tcagctcgat
     2101 tgctttcaca tttggcgctt cgccaatttt gctacaaact tctacatagt cttcttcaca
     2161 agcaccagca acatttgcga tgatgggtaa ctcattgtac tcctctaatt ctggaagaag
     2221 tttatgcata acaacgtcta gaccaggatt ttgcaaacca attgcattca acatgccaga
     2281 tggtgtttcc gccactcttg gtgtgggatt gccaaagcgg gcatttggag tcgttgcctt
     2341 gaccatgatc gatccaagct gattcaaatc atagtatttt ccgtattctt tgccaaaacc
     2401 gaaacagccg cttgccggca tgataggatt ttttaattct agaccgggga gcttgactgc
     2461 taaaggattc tcattcatat aattacctct cctattttaa aaatcggtcc ttcgtcacaa
     2521 actttcacac tttttgttcc tgtttcatct tccggcgtat gacaaacgca agcatagcaa
     2581 gcccctatcc cacatgccat gcgggattct aatgataact ggacattttg atgcgaagaa
     2641 aacagctgtt ccactgtctt caataacccg tttgaaccac atgcaaaaac agctgtaggt
     2701 tccgtcttcg ttcctaacaa taaattaccg acatttccgt gcataccgta tgttccatcg
     2761 tcagtagcga ttcttgtttc tcctagacga ttaaattctt tttcataata aacgacttca
     2821 tgtgtggcaa aacctaaaaa atgcgttggc ttaattcctt tttcgactaa ctgttttgat
     2881 aactcatata gaggagggac accgattcct ccaccgatta taaatacttc gtctcctgta
     2941 tgaagattgg acaaatcaaa accattgcct aaaggaccca tgacatctaa atggtctccg
     3001 gcagaaagag tagagaagac tctagtcccc tcaccttcca cccgataaat gatacggcaa
     3061 gtatttgttt cgtggtcgat atgattcaag ctaatcggtc ggcgtaatag caagtctgca
     3121 cgcggcacga gaatatgcaa gaactgtcct ggttgctgca tttcttttac tagatcacct
     3181 ttcaatgtca tttcaaaaat ctttggtgcc agctgttttt gctgaacgat ttccatcatt
     3241 tcttgtttca tctgtcccct cctgcaacgg tttttcgtct ttttgtctta acatgtgctc
     3301 gccgttaaat agggttagtt gaaaaagcac gggattccat cactcgaacg atcgcatctg
     3361 ctgtgtctaa agaagtaaac aatggaatac catgttcaac tgcttctctt cggatgatga
     3421 aaccgtcttt agaagcattt ccccgatctt tatcaatcgt attgacaacc acttgtgttt
     3481 taccatctct tattaagtcg actacatttt tttctgctgc ttcctcagaa attttcgcta
     3541 ctgtttcaac gaccagacca tttttttcga aataagcagc tgtatgtttc gttcctatca
     3601 gactatagcc aatttctgta aaacgtttag ctaattctag tgcttcttct tttgtttcgt
     3661 ccgcaatcgt aaataatacg gctccatatt caggcaagtg taatccagaa gcttcgaatg
     3721 ccttgtacaa agctttgtct aattgtctgt cagatcccat tacttctcca gtcgatttca
     3781 tttcaggccc taagtaagta tcaactttct gcaatttcgt aaaagaaaag acaggtgctt
     3841 taacatgaac ttcttttgtt tctggataaa gtccgttttc ataaccaagt gtctttagtt
     3901 tctctcccaa aatagctttc gtcgcaattt gtgccattgg aattcctgtc accttactta
     3961 agaatggaac agtccgactt gctcgaggat tgacttcgat cacataaacc tcattttcat
     4021 ggatgacaaa ctggatattc atcatcccga cacaattcaa acctaatgct aagcggatcg
     4081 tgtaatcttc gatcgttttc ttgatcgatt cagataatgt ttgaggtgga tacacagcca
     4141 ttgaatcccc tgaatggaca ccagcacgct caatatgctc catgatccct gggatgagta
     4201 ctgtttcacc gtcacaaatc gcatccactt cgcattcacc accaagcaag taacggtcca
     4261 ctagtactgg atgttctgga gatgctttca cagcatgttc catgtaatct tctaaatctc
     4321 gctggttttc aacgatttcc atcgcacgtc cgcctaatac atagcttgga cgaacaagaa
     4381 ctggataacc aattctcgaa gcgataacca cggcttcttc tttacttgta gcagtatccc
     4441 ctaaaggttg aggaatatcc aactctttca gcgcttgctc gaataaatca cgattttccg
     4501 cacgatccaa gtcttcgatc gttgtcccta agatttttac accagcagca gtcaaaggtt
     4561 cggctaagtt gattgctgtc tgaccaccaa attgaacgat tactcctatc ggctgttcta
     4621 gctcgatcac attcatcaca tcttcgaagg tcaatggctc aaaatataat ttatccgaaa
     4681 tagaaaagtc agtcgaaact gtttcaggat tgctgttcat gatgattgct tcgtatcctg
     4741 cctgctggat tgctttgaca gaatgcacag tcgcatagtc aaattcaacc ccttgtccga
     4801 tacggatagg accagatccc agtactagaa ttgagggctt ttctgatcgt gaactttcat
     4861 tttcatattc ataggaacta taaaaataag gtgtttttga ttcgaattcc gctgcacaag
     4921 tgtcaaccat cttatataca ggaatcaaat cattttcttt tctcatctgg cgaacggctt
     4981 cttcgtttat ttcccacagc tccgccactt ttttgtctgt aaaaccgttt tgtttcgctg
     5041 ttttcaatat cttgtcatcc aacggctgct gtttcaactg ctgttcgatt tctacgatat
     5101 gcaacagttt atctaaaaag aataaatcga tttttgtcaa atccgctaat tcttctatgg
     5161 tgtaccctct tctaatagct tcagctacat aaaacaggcg atcatcttgt gctcgaacca
     5221 ctttttggat taggtcatcg tccgtgatgt ctgccaactc aggaagttcg atatggtatg
     5281 taccgatttc taaagaacgc acagctttca ataaagactc ttcgatattc cgaccgatag
     5341 ccatcacttc accagttgct ttcatctgcg tgcctaaaag ccgttctccg ttttcaaact
     5401 tatcaaacgg ccagcgagga attttagcta caacataatc taatgcaggt tcaaattctg
     5461 caaaagtcgt tcctgtaaca ggatttttca tttcgtctaa tgttaatcca agcgctattt
     5521 tagcagctag cttagcgatc ggatagccag tcgccttact tgctaacgca gatgaacgag
     5581 aaacacgcgg attgacttca atcacataat aattaaaact atgtggatca agagcgagtt
     5641 ggacgttaca gcctccctcg atcttaagtg ctcgaataat cgaaagagaa gcatcacgaa
     5701 gcatttgata ttcatggtca gacaatgttt gactaggggc aaatacgata gaatcacctg
     5761 tatggatacc caccgggtca aaattttcca tattgcagac aacgattgca ttatcagccg
     5821 aatctctcat cacttcatat tcaatttctt taaaacctgc aatacttcgt tcaatcaaac
     5881 attgggtagc gggggaaaga cttaatccat tttctgatac gatacgtaat tcttcttcat
     5941 tttcacacat acctccacca gttccgccta aagtaaaggc tggacgaacg atgacaggat
     6001 agccgatttt atttgcaaaa tctacagctt cttctactgt attgacgatt tcagactcgg
     6061 ggattggctg attcaattct ttcatcaact gtttgaatag atcacgatct tctgcttgat
     6121 cgatcgcaga aagctttgtt cctagaagtt ctatgttcaa ttcttctaaa atacctgatg
     6181 ctgccagctc cattgccata ttgaggcctg tctgtccgcc taaagttgga aggagagcat
     6241 ctggacgctc ttttcgaaga atccttgata caaattcaag tgtgatcggt tcgatatata
     6301 cttgatctgc cacttcttta tccgtcatga tcgtcgcagg attagaattt actaaaacca
     6361 cttcatatcc ttcttctttt aaggcaaggc aggcttgtgt tcctgcgtag tcaaattctg
     6421 cggcttgacc aatgatgatc ggaccagatc caatcaccat aattttcttg atatctgtac
     6481 gtttcggcat ctgtttactg ctcctttcct gcgtccatca tttccataaa ttcatcaaat
     6541 aaatgtagtg catcatgcgg accaggggca gcatctggat gaaactgcac actgaaagcg
     6601 ggataatctc tgtgtttgac tccttctact gttccgtcat ttacttctac atgagttacg
     6661 atgagttttt ctggatcaat cgtggcttca tcgactgcat agccatgatt ttgagaagta
     6721 aaatcaattc ttccggtcgc tacttctcgt accgggtgat ttaatcctcg atgtccgaat
     6781 ttcattttat aggtatctgc accgttggct aaagcaaata actggtgacc gagacaaata
     6841 ccaaaaatcg gtacttttcc ttggattttt ttgatcattt cgattgcttc tggcacatct
     6901 tttggatcac caggtccatt cgtcagcatg actccgtctg gtgatagcgc taaaatcgtc
     6961 tcggcatctg tgttataggg aagtactgtg aggttacagt ttcttttact caattctcgt
     7021 aaaatactat gtttcaagcc gaagtcaatg acaatgactt tccgacctgt tcctggactt
     7081 ggataaggtt tgttagttga gacttgctgc acttgattgg ttgctagaac ggttgctttc
     7141 agctgatcaa atgcatgttc gaaggaatct ccagcatcaa cgatactagc tttcatcgtt
     7201 ccgacttcac ggattttgcg agtaagggcg cgcgtatcga tacctgatat tccaggaatt
     7261 cctttttgtt tcaaaaatga atctagcgtc atttggtttc gccagtttga agctacacgt
     7321 gcatgttctt ttactactac tcctttgcat gttggagaaa tcgattcata atcatctcta
     7381 tttaccccat aattacccac cataggatag gtaaatgtaa tgatttgacc gttaaaactt
     7441 tgatcagtga tagtttcttg ataaccagtc atacttgttg taaaaacgat ttctccgaag
     7501 acactagcat ctgcaccaaa agcctttcct tcgaaaactg ttccatcttc taatataagc
     7561 aaacgttcca tacttttatt ctcccttctg ccacacaagt tttccgttga caaaagtcat
     7621 ttgtgtttcg ccttttactt tccagccgat aaaaggtgta ttctcccctt ttgataaaaa
     7681 gtcttcttta tcgatcgtgc aagtttgtgt aatatcaaaa actgctacat cagcgggggc
     7741 accaaccgtt agcgttcctg cattcaaacc aaaaatctca gccggtttaa ctgccaacca
     7801 attgatcact tgttccaacg tgaatcgacc agtttctaca aaatgagtat agatcagttg
     7861 aaacgctgtt tcgcttccta cgataccaaa tggtgatttc atgaaacttt ggcttttttc
     7921 ttctaatcca tggggagcat ggtctgtagc gatgcaatcg atcgtaccgt caagcaagcc
     7981 ttcgatcaaa gcttctctgt cctcccgtcc tcttagcggc gggttcattt tccaaaagcc
     8041 gaaatcttcg ggaatatctt cgtcgatcaa aataagatga tggggtgaaa cttctgctgt
     8101 tacgtggatt cctgcttttt ttgcgtctct gattacacgg acactttctt tagtagaaac
     8161 atggcaaaca tggtaatgaa caccagttgc ttcagctagc aacagatctc tagcaatttg
     8221 agaagactcg gttacgctta agatcccggg aagaccaagt tcttctgcct tcttgccagc
     8281 gtgcataacg ccgccaaata ataaagattc atcttctgta tgggctacta gggctttatt
     8341 gttttttgca gcttctttca tagccagata catcgtccca gctgtttgga cacctacacc
     8401 gtcatttgtg aaagcaaaag caccttcttc aatcagtgct tcttgatcaa ctaatttctc
     8461 acttcgcaga ttttctgtga ttggcgcata ctgcaatacc ttcacaactg catcttttct
     8521 aatgatgtca tatacttgtc tcagcttttc tgccgtatca ggtacaggat ttaaattcgg
     8581 catcgcgcat acagtagtga aaccgccacg agcagctgag cgagtcccag cttcgatcgt
     8641 ctccttgtat gtaaatcctg gctctctcaa atgaacatgg acgtccacta aaccaggtgt
     8701 gatcaattgt ccctttgcat caaacacttc atcaaattcg gcttctgaga atcctgtacc
     8761 gattgctttg attcgcccat cttctatcca aatttctgct ggtgtcgtca tattttttcg
     8821 tgtattgatc tgaccgtttt taatgagtgt tttcattttt tcatcctcct ataattacgc
     8881 ttttccattt agcactgctt ctaagattgc cattctgacg aatactccat tgctcatttg
     8941 ctgaacgatc cgcgactgta atccttccac taatgaatca gctaattcta catcgcggtt
     9001 aactggtgct gggtgcataa tgattgcatg tttttgcaac ttcttcgcac gctcaactgt
     9061 taacccatgt tcctgatggt agccttcttt tgagaaactt tcttttccat catggcgttc
     9121 gtgttgcacc cgaagcatca tcatgacatc aacttgatct agtagttcat ccaatggcat
     9181 ataatgtccg tacacttcga attcatcgtc gtaccattct ctaggacctg agaagaatac
     9241 ttgtgcgcct agacgtttta acatctgcat attggattta gctacgcgag agtgagtgat
     9301 atcacctacg atggcaactt tcagaccttc aaaatgacca aattcttcat aaatggtcat
     9361 caaatcaagc aagcattggg ttggatgctg tccgcttccg tctcctccat tgataatcga
     9421 acactggatt gttttacttt gtatcagttc gtcataatag ttctcatcac catgacggat
     9481 aaccgctacg tctacgccta atgctgacat cgtcagtact gtatcgtata gtgtttcccc
     9541 tttttggaca gagcttgtgc ttgcttcaaa ttcaatcact tctagcccta gttttttctc
     9601 cgctacatcg aagcttttat gtgtgcgagt actattttcg aaaaagaggt ttgtagcaaa
     9661 gtactggcgc ttttgcggag tccaattagc accttgcttg aattcctgcc ctctgcggat
     9721 caagcccata acttcttgat cagtaagtgc ctcaacggtc aataaatgct ttaagctgat
     9781 acgttctgat ttgatgatca taatgtttcc tccttagttt tcttcgcttc gtgaagtttc
     9841 tggtaagata agatttaaaa tgatgccaag tacagttgct aatgccattg ccgacaatgt
     9901 aaatgtgcct acttcaaaga cgagtccgcc aattcctact actaagataa ctgaagcaat
     9961 caacagattt ttctttttat caaaatcgat tttgttctcg attaaaatct tcattccact
    10021 tgccgcaatt actccaaata agataaaact gattcctgag atgactggtc cagggatact
    10081 taaaatcaaa gcgcttaatt ttcctacgaa tcctaaaatg actgcaaata ctgcagctcc
    10141 accgatcaca aacacgctat ggacacgtgt gatagccaga acaccaatgt tttcaccgta
    10201 acttgttaca ggaggacctc cgacaaaggc tgccacgatt tgtgctaacc catcacctgt
    10261 caacgtctta tgaagacccg gttcttcaaa gaaattacgt ttagttagtt tattcaatac
    10321 cataagatgg ccgatatgct ctgtcatcgt cacaaaagcg atgggtgcca ttgttgtgat
    10381 tgctccaaga tatagctttg gttcatattg tacaaaggga atctcaaagt taggaacagc
    10441 aaaccaggca gcgtctacga ttggcttagt atccacgatt ccaaacagca aggctacgat
    10501 gtatccgcta atgataccta gtaaaatcgg aatcaatccg agaaaacctc ttagccacat
    10561 gttgaagaaa attgttaatc ctaatgtgat cagcgctaca gcaatatact tgaaatcata
    10621 cgtgccctga ttatacatag catttgttgc tgcatttgcc gcaagtccca acccgataac
    10681 catgatgact ggaccgacga cgattggagg caagatttta tccagccatg ctgaaccgat
    10741 ctttttgatg atcagcgcaa caatcaaata gactaatcca gttgtgactg ctccttgtgc
    10801 aatcgctgga taaccatctg ttttcatcaa aagctgcatc gctgcaatga aagcgaagct
    10861 gcttcctaag tacgcaggta tctttccttt agtagtaaat aagtacacca atgtacctag
    10921 tcctgaactg actagcgcaa tacctggatc gatacctact aagatgggga ctaacacggt
    10981 tgctccgaac atcgtgaaca agtgttgtaa acttaatcct acccaatgtc ctggggttgg
    11041 gcgatcgtgg atatctaaca ccacgtcatc attatgaaat ccttttttct ccgacatgtt
    11101 tctctctcct ctaatcttcc tctttcaaaa tcatgatacg atcttgtcca tcaagctctt
    11161 gcatctctac taaaatctct tccgcccgag atgttggaat gttcttccca acataatctg
    11221 cacggattgg caattctcga tgcccacgat cgaccaggac tgctaatgaa atttttcttg
    11281 gtctgccaaa atccattact gcgtccattg ctgctcgaat cgttcgtcct gtatacaaaa
    11341 catcatcaat caaaataact tcttttcctt ctaaggaaac tgggatgtca gaagaatgaa
    11401 gttccggttc ttctggattt tcttttttgt catctcggta taaagtgata tccagttctc
    11461 ctacaggaat atcgatatct tctagctgct tcaggcgttc ggcaattctt gatgcaatgt
    11521 agattccacg tgttttgata cctactaata caatatcttg gatactatga tttctctcga
    11581 taatctcgta agtaattcga gtcaatgctc gcttcatcgt tacctgatct actacttctt
    11641 ttgcttgcat attcattccc cctacttttt tgcataaaaa aactcctgcc ctaagaggac
    11701 aggaggaatg tttagactga gcgtatactg atacactgat agctatacta tgtcaatgag
    11761 caatctactt atggcgcacc atacgtatcc ttgctcccac ccttcttagc ctcacgggac
    11821 taaacttaaa ggaattctat taagttttat gctttcgttg ttaattacta taccgttatc
    11881 taaattaaaa tgcaatgttt tttcttaatt tttctaaagt tttttcaaaa acttctggaa
    11941 gaggtgcttc aaagatcatc ttttcgtttg tagtcgggtg cgtaaaacct aacatttgcg
    12001 catggagaaa ctgaccattg cctttcaaag ttttcttcgg tccgtatact ggatctccag
    12061 ctaacggata accgatatac ttcatatgca cacggatctg gtgtgttctt ccggtttcta
    12121 gttttaattc aaccagagta aatccttcga aacgttccaa tacagtaaaa tgtgtgacag
    12181 ccggcttccc atcttctctt atcgcctgca ttttccggtt ttccttcgaa cggccgattg
    12241 gcgcattgat ggttcctttt tcgtgaggaa tctctccatg gactaaagca acatatttgc
    12301 gcaaagaggt cttatctttt aattgctgag ctaatgattc gtgtgcctgg tcatttttgg
    12361 caaccattag cagtccggaa gtatctttgt cgattcggtg aacaatacct ggacgaataa
    12421 cgccgttgat cgtagaaaga tccttgatat ggtacatcag cgcattgacc attgtgccat
    12481 gcgtatgacc tgctgaagga tgaacgacca ttccttgagg tttgtttatc accgctacat
    12541 cttcatcttc gtaaacgatc gtcaacggga tattttctgg gaccacatct aatgtttctg
    12601 gttcggggat caagacagta atctcgtctc cttgttttac tttgtaattt gctttgactg
    12661 gctgtccatt gacagaaacc gctccatttt tcagccacag ctgaatttgc gaacgactgt
    12721 aatcggtgaa taaattagtc aatactttat cgatcctacc agattcatgg tgaatcgtcg
    12781 ttttaagttc tgtcattttt ttctttgatc cttttcatct aaaataatat aaattaatat
    12841 acaaatcact ccacatacaa gtgtcacatc tgctacgtta aaaatcggaa agctcataaa
    12901 atctgtctgg aacatatcta ctacatagcc aagacgaata cgatcgataa aattgccaat
    12961 cgcaccagct agaaccaaac tcaatccaat catgaaccag cgattacctt tttcacgatt
    13021 tttaatcatc aatgtgagaa tcacaacgac tgcaatgagt gtcactatag taaagaacca
    13081 catcttccct tctagcatac tccatgcggc tccagtgttt cgaatatgat tcagtgacaa
    13141 aatacctggt ataagatttt tcgtctctcc aagcgctaga ttatcagtga tccaccattt
    13201 gaccaactga tccactccta ctagcaaagc gctgaatatc caataaataa ttaacaaaaa
    13261 atcaatcctt ttctatttgt ttataaatat cacgaggtcg tacgatcccg agcagattac
    13321 catcgggatt cccatcttta gtgataagta cggcttccaa agtcccttgc tcacgaaaca
    13381 tcgcttcaac ctcgtaaata tgtgttttag ctggaacaaa atgataattt gtgtactttc
    13441 cgttttggat gatcaaatcc aacgctcgtt tatttgttaa atcaaccgga cctttttggc
    13501 tttcttttgc tagccaaaac ccgatattac gtaaagtaat caatgctaca aattttcctt
    13561 tattgtataa cggaaattgt gaataccttt tttctgctac tatctttaac agttcaagta
    13621 acggaagatc ttgttcaaaa cctgttacac gttttgcaaa tcgaggcagc acggtttcag
    13681 gctgaatcag ttcttgttcg atcagctgga ttcgcttgac tgtccaatca tttggctctg
    13741 caatgacaaa atcgactgcg atccgatcat ggacgatcgc attccttaac tgagcaagct
    13801 gtaaaagatc atcttcgtat tttctgatca ttaattgttt tctttgagct aggcgtctga
    13861 caagttcggt aaatcccata tttcgtgcat ttcccatctc gtctctcatc catttttcga
    13921 ttcgattgaa actgattaaa aaaagatcag agtttgccat aattttcctc cttgatcaaa
    13981 tatgcccggt tttttatata gaaaaagaac gcaatcaaca caataactgc aaaaaaactg
    14041 aaaaataaat tttgtaggaa aacggccccc aacccagttg ctagaaataa aaacggatag
    14101 atttgaagaa tcaagtaatt cattgtgatc acataagcag gctttgcttc tttcactgta
    14161 taaacggggc tttttagcca ataaaaggtg acctgcatcg taaagggcac ttccagatca
    14221 agcgttatct ttttttcatg actgagaaca ctgcgttttt catcgttgat tcttagctga
    14281 atcgagctac ccataccgta aaaaccggtt tttcttataa atgtcgtttt catcataccc
    14341 tcctattatg ctttagtata gctcaaaata caataaagaa aaagaatgat cctagtgtaa
    14401 acaaaattaa ttccctatcg tctaaaaaaa gaagctgtag tcaaaataca gctc
//
LOCUS       DACDLM010000065        14303 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.067, whole genome shotgun sequence.
ACCESSION   DACDLM010000065 DACDLM010000000
VERSION     DACDLM010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14303
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.067"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..210)
                     /locus_tag="IV356_002165"
     CDS             complement(<1..210)
                     /locus_tag="IV356_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP9015831.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETI"
     gene            complement(537..1904)
                     /gene="nhaC"
                     /locus_tag="IV356_002166"
     CDS             complement(537..1904)
                     /gene="nhaC"
                     /locus_tag="IV356_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAP9015832.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(2013..3434)
                     /locus_tag="IV356_002167"
     CDS             complement(2013..3434)
                     /locus_tag="IV356_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP9015833.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(3677..5554)
                     /gene="tdc"
                     /locus_tag="IV356_002168"
     CDS             complement(3677..5554)
                     /gene="tdc"
                     /locus_tag="IV356_002168"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAP9015834.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(5845..7101)
                     /locus_tag="IV356_002169"
     CDS             complement(5845..7101)
                     /locus_tag="IV356_002169"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HAP9015835.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     gene            7681..8982
                     /locus_tag="IV356_002170"
     CDS             7681..8982
                     /locus_tag="IV356_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAP9015836.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(9051..9650)
                     /locus_tag="IV356_002171"
     CDS             complement(9051..9650)
                     /locus_tag="IV356_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP9015837.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            9904..10785
                     /locus_tag="IV356_002172"
     CDS             9904..10785
                     /locus_tag="IV356_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9015838.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            10798..12408
                     /locus_tag="IV356_002173"
     CDS             10798..12408
                     /locus_tag="IV356_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HAP9015839.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(12485..13144)
                     /locus_tag="IV356_002174"
     CDS             complement(12485..13144)
                     /locus_tag="IV356_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAP9015840.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(13427..14092)
                     /locus_tag="IV356_002175"
     CDS             complement(13427..14092)
                     /locus_tag="IV356_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015841.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
BASE COUNT         4190 a         2893 c         2613 g         4607 t
ORIGIN      
        1 aatcgtttcc ttcttcccat ttttcactac aattactttc ccgtttccat ctaccacagt
       61 agaaccacaa tttctacagg tatggggagc aggtgagaaa acagcatcga cgatcaacgt
      121 ctttttcttc tgaaaggtct cgtaagagac ctctgtaatc atcaaatctt tctctattaa
      181 tcgcagcatt tttttgatag aatcattcat atagcatatc gtcctctcag ttgtttattt
      241 tgtcgtgatt taatcatact agagaacgat atgtttttta atacctaaaa taaaaatggg
      301 gctgaagaat caattctgat tcatcagtcc cataaattat agagcctaaa aaagagcgtg
      361 ggacaaaagt aaagaacact tttgtctcac gctctaaaca cgtataaacg gcggaagcag
      421 aagcaactcc ttcggaaata agctgaaatt cacaaaaatt taaaaagcaa ttttcttgag
      481 tttcttctta tttcttggag ttaaacgctt ctgtcccagc ctcttttttc cttccttcaa
      541 ttttttacac gtcgacgatt caataaaaaa ccgcctaata ttgtaaagac aggtgcaaga
      601 atcgagaaaa aggcgaatgg caagtaatgc aacgcgctaa ctttcatcgt tcccataatg
      661 aatgtgccgc tgactcccca cggtacgaga gaattgacgg tcgcacctga atccgctagt
      721 gttcgtgtca aataggtttt tgataagcca acgtcatcaa aagaacgctt gaatgtttct
      781 cctggaagaa tgatggacag atactgttct ccaacgatca gattgattcc gatacagctc
      841 aaggcagtaa acccgactaa acgagaaggt cggtccatct tttcttttaa ttcttgaacg
      901 atggtatcaa cgatcagata tttgatcagt aacccaccta atgccaatgc aagtaaaatc
      961 aaactagcag aacctaacat actcatgatc ccgcctcgag aaagcagttc atctagcttt
     1021 ggatcaggtg tatttgcgac ataaccattc atcaagatgt ctgctgcttt tccgaccgtc
     1081 aaacttttct catggataaa agaaagaacg agagcagctg tcgatcccgc tagtaatgta
     1141 gggatagccg gaattttttt gattgccccc ccaaataaaa taactagtgg aatcaatgtc
     1201 caaggagaga tccaaaagct cgctttcatg ttttggatca tttcattgat actagctaga
     1261 tcggctgaat gactgttatg tcctaatatc gtataaaaaa tcaacgaaag gacgaatgct
     1321 gggaaatccg tataacgcat accagcgata tgttcgaata gattaactcc tccaataccc
     1381 gctgccaagt tggtcgtatc tgataaaggc gagcagttat tccctaaaaa ggcaccggaa
     1441 acgactgcgc ctgtagtcat tgcatcattg aatccaagta aatgaccgat ccccaaaaaa
     1501 gcaattccaa tcgtcgaaat cgttgtaaat gaactgccga cagtcactcc gacaattgca
     1561 caaacaagaa atgctgtcgg taaaaagaaa cgcacagaaa caagtttaaa tccataaacc
     1621 ataatcgtag ggatggttcc agataaaatc catgaagcaa ctaagacacc aatcaaaaga
     1681 aaaatcagga ttggaatgat ccctggagtg attcctttga tgatcccgtc atggatctca
     1741 tcccatgtga actttttaaa tctgccataa aacaacaaac acatgaaagc tgcaaggatc
     1801 gggatatgtg gcgagagctg gaatccgatg atcagtactc ctaggagtgc caacaacacg
     1861 atcaatacag cgatactttc ttttaaagaa atatttttat tcatcgtcga tctcctattt
     1921 caaatgaaaa ggccctgcca tgaaaaaact attcacttgg caggacctcc tactaaatca
     1981 gcgacaaaac gtcggctgaa agacttattt ttttattttt cttctaaact tttttctacc
     2041 tcaatccccc aagaatcttt cttgaagtga ttgatgatca atggaataac gaacatgacc
     2101 actgtgatag ctgctactaa taatgcatca ctcaatgtcg ctgtacctaa tgtagcaaat
     2161 acgacaacga tgatagagaa gatcagcatg cagctgacta cccaagctaa tccgtttccg
     2221 tttttaccaa ttcggtaagg acgttcgaat tctggatgtt tcttacgcat tttaagcaat
     2281 gaaacagcaa tcaaaatgta cacgatacaa taaataacag ttgtagcatt tgtaagtgtc
     2341 aagaatacag cacttacgtc atccattaca ccataaagca aagcaaataa tgaaataacg
     2401 attgattgtg ttagaacgac atttctagat acgccgtatt tgttttcttt atggaatccg
     2461 aattttggtg gaaggaatcc ttcacgagct acttggatga ttgtttttga tggtccagta
     2521 acccaagctg ataattgtaa aagcacacca ataaatacca tgaagctgaa gatatttccg
     2581 atcacttctg gtaagcctag gatttgacag tcaatcaaga taggctgcgt gatatttgct
     2641 aattccattt ttccatctgg tacgacattt gctacaagca tcgcattgat gacattcaat
     2701 aaaactaatc cgatcaaagc gataaatacg ccttttgtat aattttttgt tgcgtctttc
     2761 aaacgaggca tgtaaacaga actcatttcg atcccaacaa aaataaatgt gataccagct
     2821 aagtatttca atgaatcaat atgttccaag tcagggaaag cttttgacca tgaaaagtca
     2881 cctagatagc cgtttgagac tagtccgact ttgaaggctg ccaaaacacc taaaacgaac
     2941 atgatgacta ctgggatata tacccctagc catacaccga tgttcccgcc gacttttgcc
     3001 atatcgaatt tcaagttcaa gatcgtgatg atccagtaga taactaaaat acaacctaaa
     3061 acgaaccagt gattattgcc aagttctaca ttaccaaatg tgtttcctaa caatggtcct
     3121 aaagtagaag cgaccattac catacctggg aacatttgca cccataatag ccatgcaacg
     3181 acaaatcccc atttgctgcc cagtgctgtt tttacccata actgaggacc gccttcttga
     3241 ggaagcatcg tggaaagctc accggaaacc attgatatcg gaccggcaaa aaacaaaact
     3301 gcaaaaattg aataaaaaat caatgtccaa ccgactgcgg ctaacgtagg aatactccga
     3361 accgttgcac acagtgccat tgtcagaccg ataaaggtcc caagacccat tttacttact
     3421 tcagatttac tcaccgttga cactctcctt gattttttgg ataaaataac ggtgtctttg
     3481 aagtagtttc agcaataaac gaaacaattc agcgaatatt tgaggggatt ctttgagttt
     3541 attgcttgaa gggtttcttc aaagacaacc tcaaaacaaa gggatcgaag agcttaggtc
     3601 tccccttgct cttcagatcc aaacatgcgt cagaaacagt tagtattcaa gctgttttct
     3661 aacatgatta ccttgcttat tttgcttcgc ttgccaataa ttggtctgcg tagatttttt
     3721 ccaatttttc ttgaagagct gctttgattt tttcagcata ttcttcaaag tgttcttctt
     3781 tgttcatgta tggtgtcatt acgctggcac gcaatacagt tacttttccg gcacggttcc
     3841 attcttcatc tgagaatcct agttggttca caaattgtaa tgggctgttg ccatagtctg
     3901 ggatagcaaa gtcagtatgt gaagttaaga actcattacc gtaaatgctt cctttcacgt
     3961 atgaagaata atcatatacg tcatggttca atttattcat tgcaactaag tcatcgttgc
     4021 ctttttcttt gaatacatag tctaccatat tgaaatctgg ataagttaat ggatgaactt
     4081 cgatttcttt gtctcctact ttaaatgaca agtcattcaa gaagttgtag aaacgatgtg
     4141 caccttcgat tgatgcaccc attaatttac catatcctgt gacattcaaa ggtaagacat
     4201 ggtgtgctgc ccaaacgctg gctgctgttg cccctgcttt tgaaccttcc aagatataag
     4261 ccccaagtaa tgctgggata tctgcgcctt tttcaaatac atatgtcgca aagtaagaga
     4321 taacgtctct catgcggata tctttgatga cgataccacc ggcagaatat ggaacatagc
     4381 ccattttatg tgggtcaatc gttacagatt ctgcttcttc gattgcttta tacgcactgt
     4441 gtacttcttc taagatataa tctttgtttt ctgtaaagac attgtatttg taatgaacat
     4501 cttttaaatc ttcaaatgga atgaagttgt tgtcttcgtc taagaaaatc gcacggccgt
     4561 atccgccata agcagcatct acgtgtaagt agaagtaaat accgtctttt tctaatacgc
     4621 gacgcaatgc aacgatttta tcgataccgt cgattgctcc ttcttctgtt gatcctacaa
     4681 caccgactac acctaggatt ggtgtttttt cagctgctag accacgaacg attttttcaa
     4741 gttcgttgat gtccatgcga tagttgtggt caactggcac tggaatcact tggtctaaac
     4801 cgataccgat gatgtcggca gcttttagcc atgaatagtg tttagtttgt ggaaccaacc
     4861 attttcctaa tttttctaaa tgttttccgc tacgtgctga gtgagctttg atttcgtcga
     4921 ttttttctgg gacgctgtct aacagattca tgatttcttc tgttgacaag ttcattaatt
     4981 cccaatcgct ttttccagca actagttcag gtgtcacttc tttcattgca agcggcaatg
     5041 atttgatgtt gcgggcatac caaagtcctt ctaagtttgc taaagaacca tcagcaacga
     5101 tgtggcccca gccatcttta tagctcatta attttgcaaa ttccattcct acttcttctt
     5161 ccatttggct tgttgcagga gaagattcat aggcaacgtt attaccattc catagcatag
     5221 caaaattgta cgctagtaaa gatggcatca atgtttcaga gttcatatga ccccagtaac
     5281 gtccggcatt atgccaagga acggaatggg tacgcatccg cgctgaaatt tctgatagaa
     5341 catcctttgt tttattcaca gtgtgttcaa aactagcact gcttttttct tctggcgtaa
     5401 taataggcat gtcttgaggc atgtagtttt gacgccagcc taaatgttca tccaccaatt
     5461 cattcaacaa agctttatag atttggccgt tctcagcttt gtccccaatg aatagggcat
     5521 ttaggtttag atctttcgac aatgattcac tcatagtgaa accctcctaa aaaaatattt
     5581 aaattttgtc gagccctaca ttacacctgt tcttctattc tgtaaactaa gttttggcct
     5641 gatttttaat catattttaa tatgtatcaa ttatccgaat tgttcacact tttgaaataa
     5701 ttaaaaaaaa cgagggaatt tacaaatgta aactccctcg caaagattgt attaacgaca
     5761 accagcgttc tattttagga tgggtttcaa aattggaatg ttgtaatagt atttcccttt
     5821 ttcaaggtaa aaacttacta aattctaatc aattactttg gccaaaaagt aatttttctt
     5881 accttttcga ataaccacaa acttaccatc gaattcatcg gatggattta tgacaaaatt
     5941 taaatcggta acgcggtcac cgttaatact tatagctccg tttgaaacat cttcacgtgc
     6001 ttgacgttta gatggttcaa tttttgtgga aacaagcagt tccacgatat tttcaggtgt
     6061 gcttgaaatt tcaacgttcg gcattttacc gaatccttgc gcgatttctt ccgcatttag
     6121 ttctttaata tttccagaga acaatgcttg cgttattttt tgcgcttctt tcaagtcttc
     6181 ttcactatgc acaaatcttg taacttcttc tgccaaacgg cgttgtgctt cacgtttctc
     6241 aggttctgtc tctacttttt tcgctaagtc ttcgatttct tcttgagaca agaaagtaaa
     6301 gaatttcaag tatttcacta catcgcgatc atcttgattc aaccagaatt ggtagaactc
     6361 aaatggtgaa gttttcttcg gatcaagcca aacggcaccg cctgcagttt ttccgaattt
     6421 cgttccgtca gccttcagca tcaatgggat cgttaaaccg aacgcttctg cttctggtcc
     6481 ttctaatttt cggattaggt ctaatccagc tgtgatattt ccccattggt ctgctccacc
     6541 gatttgcaat tgcacatcgt atgttttatg cagatgcaaa aagtcgatag attgcaggat
     6601 ttggtaagta aactctgtaa atgagattcc tacttccaaa cggctggcaa cgatatcttt
     6661 tgctaacatc gtgttgatgt tgaagttttt accgtagtct ctcaaaaatt caagtaaaga
     6721 gatttttgac aaccagtcgt agttgttcac aaatgtgata tttgcatctt taccaaacaa
     6781 ttttctcatt tgattggaaa gtgcgtccac gttatgttgc acttgttcca tcgtttgcaa
     6841 cacacgttct gttttgcggc cgcttgggtc gccgatcgtt cctgttccgc cgccaatcag
     6901 aatatatgga tgatggcctg ccaattggaa tcttttcatc atcataaatg gaatcaaatg
     6961 tccgatatgc atcgaatcac cagttggatc aacgccgcaa taaagtgaaa tgctcttttc
     7021 ttcaacgagc tcgcgaagtc tttcttcgtt tgtttgctga ttaatggcgt cgcgccaagt
     7081 taattcatca ataatattca ttttactgac ctccgtgtag tttttttatg aaagcaggaa
     7141 cctgctagca tgtgtaatta attatttctt caggatagga taggaaataa aaaaagtccc
     7201 ttggcatata agccaaggga cgaaatctcg cggtaccacc caatttgtat gtctagatat
     7261 ccaacatacc tctcgaacat ttaacgctgt cgcgtggcaa tcactgccaa agactcctga
     7321 aatgtaattc gctttaaagc atgtactggt ttgcagcgac caccagcttt ctgaaacatt
     7381 ggctttaaca actacttcgt ttcgatcttc gtcttgttat tattaatatg tgtctatcat
     7441 agagcgcaac tttttctttg tcaacagaaa aaggatattt tttttaaatt cctcattttt
     7501 tcttttttga atccgctcta attccgaaca ttttattttc aattattgtt aaaagaaata
     7561 actttttctg tattttttct gcaatttatc gagaagtcac tttactttgc ctcttattct
     7621 ttcttcgtta caataaggaa tgggacaagt aaaaaaatga aaaagcaagg gacgaggtat
     7681 atggaaaaaa agcaaaaaat tattttagga gccacttctg ctttaactat cgttatttta
     7741 attctaagtt tgttttttgt catccgatca tctacaaaaa aagaaccaat cattcctgaa
     7801 aaaaaaataa cagaaaaagc aaaagaaccg acagatgata agcaacaact agttactcaa
     7861 gcaaaaaatc tggctcaaag ctacgattat gaccaagcga ttgcgttatt ggaaaaagat
     7921 agtaagaacg gatctactga aacacaacag cttcttcaaa cactaaaaaa ggagaaagaa
     7981 caactgatcg actggtctga tcctactcag atctctcatg tctttttcca cagcttgatc
     8041 gtggacccgc aaaaagcctt ccactctcaa caggcacaag gatacaaaga ttatatggtg
     8101 actgttgaag aattcaaccg ttcgatcgaa caactttatc aaaatgattt tgttttagtt
     8161 aatttgaatg atttgatcca aaaagacgaa caaggaaatc tttcctttaa cgggcttgcg
     8221 ctacctgaag gaaaaaaacc attggttctt tcacaagatg atgtcagcta ttatgaatat
     8281 atggataatt ccggttttcc tagccgattg gtcgtatcaa ataacaatga aatcaaaaat
     8341 gtctataaag agaaagataa agaagaaatc ggtgactttg acatggttcc tctgatcgat
     8401 gcctttgtca agaaacatcc tgatttttct tatcgaggcg caaaaggtac cttggccctg
     8461 acaggttaca acggagtttt aggttatcga acatcaaaat ctcaatatgg agacaatgaa
     8521 aaaacaaaaa aagagattaa agaagctaaa aaagtggcgg aacagttgaa gaaagacggc
     8581 tggagctttg cttcccatac atggggtcac ttgaatatga ctcaagcttc actagaagat
     8641 gtaaaaaaag acaatgaatt gtggcagcaa gaagttgcac ctatcctagg aaaaacaaat
     8701 attctgattt atccatttgg tgcagacatc agcgactggc agccttattc agcagaaaat
     8761 caaaaatttg cttacttgaa gagtcaaggt ttcgatattt tctgtaatgt cgatgcttct
     8821 acaccagctt ggggacaatt aggtacggat ttctatcgaa atgctcggat caatatcgat
     8881 ggcattcgtt ttcaatctga tttagacgga aaaaatccta ttcttgatcc attcatcaat
     8941 gtccatgatg tctatgacaa agaagcacgc gaatctgctt gattttacgt catttatgaa
     9001 ccaaaaaagc cgaactgaca ttttatcgtc agtttcggct tttttatgct ttatttcttc
     9061 ttcggtgcga ttcccttgat caggacttct gtccattctg ctgtatatgg aagcagtttt
     9121 gcgtatatct ccggcttaga aattccttct accattgctt gaaaatagag gatcaagaac
     9181 tcatccgaat atttcaaatc cacttttcct tctttccgcc ctcgatggaa aagatcaagc
     9241 atgatactga aactttcttg cgtatacgca tccatcgcgt cagaaaattc ttttttttct
     9301 ttttttgtat agtatgtcat caaatcgata taaaattgtt tgttcactcg attgagataa
     9361 cggattttgt tttcactcat ggcaatcagt gtttcttcaa atggaagatt ttccgcaatc
     9421 aacgctttcg cttcttgccc taaatcattc ataaatgcaa aaaatacttc ataaatcagc
     9481 ccttccttgc tgccaaaata tttaaaaatc gtcgctttac ttacctgagc gttctcagct
     9541 accttatcca ttgtcactcc agcggttcct atgtctgtgt tcatcaagtc aaaagctgct
     9601 tgtaaaatct ctttcttttt ctcttgtgct ctcttttcaa aaccgttcat ttgtagagcc
     9661 tcccgtaatt ttaaactttt ataatatata tagttcaaat ttattctgag gtttattata
     9721 actatctatt gagaaagtat caagctagca attccttgtt tatgaattca ttgacagaaa
     9781 tttataaaaa gaatattatg tactaaaata ataaaaaaag ttttataaaa aggtataaaa
     9841 cctttttatt aaactattta atcttgttta gtatatattt ttagaaaaag gagtggggtt
     9901 tttatggcag aaatcgtcaa agtcacacat ttgaaaaaga gctttggtcg tttcgaagct
     9961 ttaaaagatg tctctttcac cgtacattca ggtgaagtcg ttggatttat cggaccaaat
    10021 ggttctggaa aatccacgac gattcggaca cttttaggga ttataaaaaa agacggcgga
    10081 acggcaacga tttttgggca agatgtatgg gaagatagtt tatctatcca tgaacgtctt
    10141 tcttatgttc caggcgatat ctctttgtgg ggaaatttga ctggaggagc gatcatcgat
    10201 ctcttcatga agcttcatgg aaaagggagt gctcaaaaaa aagatgaact gattcaacgt
    10261 ttctctcttg atcctaagaa aaaagcaaaa aactattcaa aaggaaatcg ccaaaaagtg
    10321 ggcttgattg ctgctttggc tgttgattcg gatctctatt tatttgatga gcctacttct
    10381 ggtttagatc ctttgatgga aacgattttc caagaagaag ttgaaaaatt gaaagaacag
    10441 ggcaaatcca tcctactttc ttctcatatt ctcagtgaag tcgagcgact agcggataaa
    10501 gtcgtgatca tacgcgaagg aacactcgat gaagaaggaa cactcgatga attgcgtcat
    10561 ttgactcgtt cgaccatcac tatagaaaca gaagcagaga atagtcactt agcacaattg
    10621 aacggtgtcc atgactttgt gcaaaaaggt cacctcgctc aatttgctgc tgataacgaa
    10681 gctttcgatg tgattttagc tgaagcgtcc aaattaggtg tgaaaaaatt tgaatctatt
    10741 ccaccgactc ttgaggattt attcatgaga cattatgaag gatgaggagg aagcgaaatg
    10801 actgataaat tttcacgctg gtccaccctt ttttctcaaa accttagccg tgactggaaa
    10861 aagatcctga tatggctagt cggtgtcact gctttttctg gtggttttgt ccctgcgttt
    10921 gaagaattga cttccggaca aggattagct ggattatacg aaaccttgca aaacccggca
    10981 atgattgcaa tggtcggacc aactccagct tcgaatgctg ctgagtatac tttaggagcg
    11041 atgtatgcaa atgaaatgtt gcttttttgc agtttgtttg ctgctgtgat ctctgtttta
    11101 cacgtggtga gccaaacgag aaaaaaagaa gaacttggtc tgattgaact tattcgttcc
    11161 tttcgagtcg gacgtcaagc aaactcttta gctgtcatcg ctgaaagtat tctgatcaat
    11221 ttgcttttag caatatcgat cagctgtacg atgatttttt tccaagcgga ttcgatcact
    11281 gcagaaggtg cttggctttt tgggctatct gtaggtagta tggggatttt ggggagtgcc
    11341 gttgcactgt ttgctgcaca actgatgcca agttcagcca gttcgaatgg tctgtcttta
    11401 gcgtttttag gtggacttta ccttctacga gcaataacag atgtagctga ttcctccctt
    11461 tcgatgtgga atcctttagg ctggtcttat ttgacctatc catttacaac taacaactgg
    11521 attcctttgc tttatttgtt tttgttcagt ctaatcttga taatcagttc atttgtttta
    11581 gaggaacatc gagatttgaa caccggctat atccccgaac gtgaaggaaa accgtatgct
    11641 aaacgttctc ttttatcctt gcgtggttta ttattctatc taaataaagg gatgacaatc
    11701 agttggctta tcacttttgg tttgatgggg gcggcatacg gctctatcta cgggaatatg
    11761 caacagtttt tagaaagtaa cgacttaatg aaacagatgt ttatccaatc tggcgtctca
    11821 attgaaaaaa actttacaag cacgatcatg gtcgtcttga tttgtctagc tgctatttta
    11881 ccaattgcta gcatcaatcg tttatttaca gaagaaaccc acggacgtat gaatcagctg
    11941 ttcgcaacaa aaatttctag gaaccaactt tattggacca atatgttact agctattcta
    12001 tttgctatat tggcaatcct gattagttct ggtgcactag ggctttctgc tttggcttcg
    12061 atgaaggatg cgaaagacat ggatctattg atgtttctta aagccgggtt caatttcctg
    12121 cctgccgttt tagtgtttat cggaattagt ggctttctat tcggatggct tcctcgaatc
    12181 ggtaaacttg cttatatcta cttagcttac tcctttgcac tcaattactt tggcggaatt
    12241 ttggatttac cagaatggtt ttccaaaaca gctgtcccta gctgggttcc acggatgcca
    12301 aacgattctt ttgatctttc cgtgttcctt acgttatcat gtatcagcct tgcactgttc
    12361 gtccttggtt ctattggtta taggcgaaga gacttactag aaggataata aaaaagcatg
    12421 tacaatttca tgctagcctc caaatctggg tcaaaaatcc aacatttgga ggtcattttt
    12481 ttatttacaa gtcttctaac tgctctttat caatgatcca gacttctcga ttctttcttt
    12541 ttacataacc attctcctct aataatttaa attttctaga taaagtttcg ggggtcgtac
    12601 cgataaatgc agcaagttct ttcattttca ttggcaggaa aaagtgatcc ttccctgtcg
    12661 ctttagctaa gtcaagcaga tagacagcga ctcgttcttc tactttttcc atcatcaaaa
    12721 aagttgtctg ctgctgtact tttgttaatt tctcaacgtt gattgctaaa agtttcagac
    12781 taagggcggg ataatgcagt aagagttccg agaaatcttt ttgtctcaat atgcaaattt
    12841 ccgttttttc tagtgcttcg ccaaataaag actcatttgg aacgcctagc aactggctct
    12901 ctccctcata tccgcccggc tctattactc gtaaaagctg ttcctttccg ctagcagata
    12961 attgatacac tttcatactg ccggaggcca cgatcactaa ttgaggttct ccattcggcg
    13021 caagaatctg ttctcctttt tccacatagt gatgtttgac aagtgcgtgt actttttctt
    13081 gatcttgctg tactaagtga ttgaacaaag gaacaaatga aacacataaa tgatcatgac
    13141 tcataatctc tcctccttct aaacagctat ttctaataaa gaaacataac ttcccttatt
    13201 ccaactgata attttctttt atcatagcat aaacgtcaag cgaaccagat accagcaaat
    13261 agagtggatt tctttttgtc ccttgcttta ttttccttct tttgagacct taagtaattg
    13321 attcctatca attttttaaa tatttacttt ttgaataatc aaaaacaaac cttcactcgc
    13381 aagccgagag taaggtttgt ttttcgcatt gcttatttcg tgttgtctat tgaaattttt
    13441 ccgcacctag cttttgatat agtggtgcta gttcttgtaa ggtttcagcg gttatttgct
    13501 caacgtgttc gatttcttgc ggatagaaga atagtttacc catttgaaag gttcggtctc
    13561 tcatcgcttt tttcaactct tcttgtttct ttgtatcgga caaatagtca gacaaagcta
    13621 agtggtcgtc aagttcatgt tctggttgcg gccatatgta ataatccttg atatcgactg
    13681 ttttgctcca ctctttcagt atcgcaagca actggttata cgctgcaatg ctaccatatc
    13741 gttcttcgct tttataatgt tggtacatca aatagatttg gtattgtttt tgattcaaca
    13801 aaactgctag acaggcattc tcgtcttgac gagattcgct tcggtacgcg ctccaaaaat
    13861 gactgcgtaa attccagcca ttcgtccagc tttcgatttt aggtttgctc atgccgtaca
    13921 tatcaggcaa aagtgcagct gtctggagct gaatctcttt ccatttttgc cagtgttctt
    13981 tatattcttt cttgatttgt tcaatcttat ctgttggatg gctctctttg agctgtttga
    14041 atgcgtagat tggtcgatca aacaactgat aatctgattt tccaagttcc attgtttcgc
    14101 ctctttccgt tatcttttgt attctacctg aattttgcga tatggacaaa tagaggttgt
    14161 gaaaaagctg ttctgcatca agtcataaga acagccaaac aaaaaactgc gatgagcatc
    14221 accgcagttt tattggctct ataatttatg gctctataat ttatgggact gatgaatcag
    14281 aattgattct tcagccccat ttt
//
LOCUS       DACDLM010000066        14174 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.068, whole genome shotgun sequence.
ACCESSION   DACDLM010000066 DACDLM010000000
VERSION     DACDLM010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14174
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.068"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..832)
                     /locus_tag="IV356_002176"
     CDS             complement(<1..832)
                     /locus_tag="IV356_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP9015842.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            complement(846..1644)
                     /locus_tag="IV356_002177"
                     /pseudo
     CDS             complement(846..1644)
                     /locus_tag="IV356_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
     gene            complement(1677..1961)
                     /locus_tag="IV356_002178"
     CDS             complement(1677..1961)
                     /locus_tag="IV356_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAP9015843.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            complement(1958..2959)
                     /locus_tag="IV356_002179"
     CDS             complement(1958..2959)
                     /locus_tag="IV356_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAP9015844.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            complement(2961..3863)
                     /gene="gnd"
                     /locus_tag="IV356_002180"
     CDS             complement(2961..3863)
                     /gene="gnd"
                     /locus_tag="IV356_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HAP9015845.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            4027..4875
                     /locus_tag="IV356_002181"
     CDS             4027..4875
                     /locus_tag="IV356_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP9015846.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            5521..5727
                     /locus_tag="IV356_002182"
     CDS             5521..5727
                     /locus_tag="IV356_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HAP9015847.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(5929..6930)
                     /locus_tag="IV356_002183"
     CDS             complement(5929..6930)
                     /locus_tag="IV356_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP9015848.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(6935..8848)
                     /locus_tag="IV356_002184"
     CDS             complement(6935..8848)
                     /locus_tag="IV356_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAP9015849.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            complement(9016..9522)
                     /locus_tag="IV356_002185"
     CDS             complement(9016..9522)
                     /locus_tag="IV356_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP9015850.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            9682..10122
                     /locus_tag="IV356_002186"
     CDS             9682..10122
                     /locus_tag="IV356_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAP9015851.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            complement(10148..11305)
                     /locus_tag="IV356_002187"
     CDS             complement(10148..11305)
                     /locus_tag="IV356_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015852.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(11308..11664)
                     /locus_tag="IV356_002188"
     CDS             complement(11308..11664)
                     /locus_tag="IV356_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015853.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            complement(11962..12855)
                     /gene="sgrA"
                     /locus_tag="IV356_002189"
     CDS             complement(11962..12855)
                     /gene="sgrA"
                     /locus_tag="IV356_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HAP9015854.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTGKVNNELDLVPII
                     PTKEQKRNAGSNLKSVLKQPDFVSRGIDHQEKAKETDNRKSDLPETGSRTLNKLITWM
                     GVLLILIVGASYFRSLFHRVK"
     gene            complement(13051..13890)
                     /locus_tag="IV356_002190"
     CDS             complement(13051..13890)
                     /locus_tag="IV356_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAP9015855.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            14075..>14174
                     /locus_tag="IV356_002191"
     CDS             14075..>14174
                     /locus_tag="IV356_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rotamase"
                     /protein_id="HAP9015856.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIA"
BASE COUNT         4159 a         2933 c         2191 g         4891 t
ORIGIN      
        1 aaaatccgtc atcatagtca tcttcgtcat caaaagatgc tgaattgtta ttgcttgtgg
       61 caggctgtac ttgtttccct ttttgcgact ggacaaagat caaagcgata ataatcccaa
      121 aaatggcata agtaaccatc gtaatatcta aagatttcaa aacaacactc ataaaataag
      181 caaggaagaa aaagaccaga taatcttttc gaccgataac gtatacagtt gtcgcgatac
      241 cgattgccgc taaccctcca cctactactt caagaatgtg gataacgact gttccctcta
      301 aagctttgat tacatcagcg atcaatggcg cccctaaata taaagcaatg aaaacaagcg
      361 gaacgaataa taaaaatgag gcaaccgttg gataaagaat aattgatcgg gccatagctt
      421 ttgtattcaa atcttctaca gctttgtctg tatatttacc taaaaaagta ttgatgaaaa
      481 aacgaaactg atacaagtaa cttccgagca atccgactgg caccgcaacg gcaatcgctg
      541 cttctggcga cagatcccct aataatgcga ctggtactgc gatagctgct gcaatagatg
      601 gttcagctgg cattgatcct cctggagaaa aaacccccat ataaatcatt tgcaaagcgg
      661 ctgtaacaat catcgcttgt gcaacttccc ccatgatcaa cccgacgact aatccagtca
      721 tcaaaggaga aaaacgtaag gtcaacgtgg ctcctccacc taaccagcgg gacataaccg
      781 cggctaccca taaagcaatc aacaaacttt gtactacact taatgtttcc atgtgtcctc
      841 ctccttcaga tctttctgat ataaccttcc agttccatca ttgactgtat cagtgatttc
      901 tgtgttacct ctataggaat caaatgcact ttctctttcg aatcaataaa ttcagccatt
      961 ttatctatta tctgtttatc tttcggaaat aatcccattt gttctagaga aaccggcagt
     1021 tctaattccc gatacaaagg atataactcg tctatttttt cccagcgacc ttctagtgcc
     1081 agttgataga aaatcccata cgctactttt tctccatgta gaaaacgatg gctttccgga
     1141 atatatttac tgatagcgtc atgcatagca tgtgctgccg catttcttgc gtatttatct
     1201 cctaatcctc caactaaacc agcaacagca aagataatct ctgaaagctg tttgaactcc
     1261 gatgtcagtt ttctttgtgc catatcttgg attgctttag cagaatgatt caaaatctct
     1321 tctttgcaga tcttcgcagt atcttgtgct agcttcaaaa atgattcatc ttgcaaaaaa
     1381 tcttgttcta agatgagctc agattcatac cattttgcta gtgtatctgc taacccggca
     1441 atgaaatatg gaacagggga atcaatcact aattggggat cctgttataa aaaaagcagc
     1501 ttgtctgtaa aagtgttctg ttttcccttc tgcttgtcca ttctccttat acatgacagc
     1561 aagaggtgtc catggagcac aattactagc taaagtaggg atgactccga aatcgattct
     1621 tgcaagattg gcactataac ccactagatc ggtcagtttt cctccgccaa cgccaactac
     1681 gaaatcgatt tcattttttt gatgattgta gctattcgtc tggcttcagc ataactacat
     1741 tctccagaat aacgatgata aaaaaattga atcgtttcgt cattcaaaaa tactaattta
     1801 ggtagcgcct tttcccatga taccgttccg tgggtgacca gtactctttt cgcgccgtat
     1861 gatttcaaga gatcagaaac ttttgaaata ccaccttctt catataaata aaattgaggg
     1921 cctgttttca cttttaaacc gttcaccatt ttcttcatca tccttttata tagttgctct
     1981 ttgtctggac agaacgttca ggaagaaggt gctgactgat ctgttcgaca tctctgacac
     2041 atttttcacc cattgcttct aaacattccc ttgtgtaggc cgatatatgt ggcgtaatca
     2101 ctacttgttc aaacgctaaa tacggatgat cttgacgtcc cggttcttct tctaaaacat
     2161 ctgtggcata tcctgcgatc tttccgcttt tcagaccatt aatcatcgct tcttcatcaa
     2221 ctagagcgcc tcttgcacta ttagatagat aaacattttc tttcatctga tcgacttctt
     2281 tatcagaaat catgtgatag ttctcttctg tcaaattcgc acataaacaa atgatatctg
     2341 attgttccag taattcttga agttctactt tttttgcacc aaagctttcg atgtataaat
     2401 ctgatttgta aggatcataa gctagaacat cacagcgaaa accgttacgc aaaatttcga
     2461 ttactccgct tccggtattt cctgcaccaa tcacaccaac tgttttgtta aacagcgtcc
     2521 taccgacgaa ctccgcccga tcttcccatc gatcgtcctt gactcttgct tgtgcttgtg
     2581 tcgtgcgtcg aagcatggac aacaaattag ttatattatt ttctgctaca gcatttcgtt
     2641 caactaaagc aggtatgata gatacgattg tctggtgttc ttttgctgct tttaaatcaa
     2701 tattgttgta accaatacca tgtcgggaaa tcaatagcag ttcatctttg ttttcaaaaa
     2761 aatctcgtcg aaaaaatggc gtaacacttg caataatgat attgaatcct ttaagtaact
     2821 ccgctagttc ttttcctgga atctcttgat caacagtaaa gaaatgaacg tctccaactg
     2881 actttaatct ttccaagtgg tgtggaaaga ctcttccgaa actgctggaa ttaacgattg
     2941 ctatatgata atctggcatt ttactcaccc ttttcaacta tttcatgtcc gccaaaccca
     3001 tttcttagtg ctgaaactac ttttgctgaa aaactatctt cttcctgtga aagattcctc
     3061 atgaacaaac tagttgcaat tactggaact ggaacagcca tttctagcgc tgtttcaacc
     3121 gtccattttg cttcacctga tgcagaaacg attccccgat aattacttaa attgggatgt
     3181 tcgtttaact gatcttccat gatttccatc agccagccgc gaatcaccga accatgattc
     3241 caaacacgtg cgacttgttc caagtcaaaa gcatactcac ttttttgtac aagttggaat
     3301 ccttcaccga ttgcttgcat cattccatat tcgattccat tatggatcat tttcaagaag
     3361 tgtccgcttc cggatgcacc agcatacaga tatcctcttt caattgctac atctttgaat
     3421 aattgttcca cggatagaaa agtttcttta tctcctccaa tcattaagca ggcttgatgt
     3481 cgtgctcctt cgattcctcc agaagtccca caatccaagt aaccgatttc atttttctga
     3541 aactcttctg ctcgacggat tgaatcttta taataagagt ttccgccttc aataataatg
     3601 tctcctggtc cgagttttgg aaaaagtttt cttaacatgt tttcggttat ctctccagca
     3661 ggaagcatta accagatgat ttttttctgc tcaaaagtag ctagaaattc agagatctct
     3721 tgataagcag gaatgtcatt ttctcttgcc tgactaacag ctgtacttga aatgtcgagt
     3781 ccttgtactt tgtgatggtg ctcttttaag tttaaagcta aattcaatcc catttttccc
     3841 aaaccaatta caccaatttc catgatagcg cctccatttc ttataccctc attatacaaa
     3901 aaaatttttt tgtaaataga ttttacaaaa atattttttg tttgattttt tcctactctc
     3961 cttgtatctt taacattaat gagaacggaa aaaatgataa tcttattatg aaaatgagga
     4021 attctcatga gcgtctccat aagactacaa atcaaaacaa tgtacaacga cttcagccca
     4081 aaagaacagg ctatcgccga ttatatttta gaaaatccaa gcaaagtaag tcatagtcct
     4141 attagcaatt tagcaagtga actgggcatt gctgactcta ctttttttca atttacaaaa
     4201 aaacttggtt ataatggatt taaagatttt aaaatggcca tgttgatcca agaaaatgat
     4261 ctatctgcta tttctatcca cgaaaatatt cagaaaacag atactgagct cactatggcg
     4321 caaaaggtgt tcgagtctag tatttcaact ttaaatgaca caaaaaagtt gttacaacaa
     4381 aaggatctaa aaaaagcggc tactattatc aatgaatcta aacgtgtcta ttttttcggt
     4441 gttggcggtt cagagattgt agcaactgac gcttatcata aatttttgcg ttcccctatc
     4501 gcaacttctc acagcacgga ttaccatatt caattgatgg aagcttcttt attgacggaa
     4561 aaagactgtg ctgttttgat ttctcacaca gggcaatcaa aagaaacaat ccatattgct
     4621 gaaaccgtaa gaaaaactgg agcaaaaaca atcgttatta ctagccaagc taattcttcc
     4681 cttgctaaac ttggcgatgt cgtttttatt tctatttctg aagaaacaga attccgatct
     4741 gaagctttag cttcccgtat ttctcaacta agcattttgg actctctata tgtgattttg
     4801 atgttttaca acgaaaaaga atcacgtcgt tctatcgcta aagttcgaca tactatttct
     4861 gaaatcaaag aatagcacca taacagaaaa agcgaaaaat ccataaaaca aaaaaagcca
     4921 ctaccaaata tttggtagtg gcttttttgg ttctgcaagg gtggtacaga acatcaatag
     4981 tcggtgggtt agaacgtatg tcatcgcatc tttggagaag gttgtattgg tattattcga
     5041 gttacttgtt agatgcgata acaaagttag tatacagtag taaaaaattt atcttttctt
     5101 ttttttatta tttttgtttc ttattttcta aaaaattaaa aaaaattttg gtgaattaag
     5161 tatttccttg ataacactgg cttttggcct cattttaggt tatcatttgt aattttattt
     5221 cacagttgat atgattgtta tgtaaaataa aaaagtttag gatacatcga atttttgggg
     5281 aaattctttt gggggtatcc taaatctttt ctattatatt cccatatttt ctattattgg
     5341 tctagacgta tgatggtaaa ctttgtacct atctgattgc tgaatcatta attgcttatc
     5401 attagccatc tttgtttcaa gttcgctaga tgatcatttt attcacatcc taacaaactt
     5461 gtcacattta tagattctta atctatttat catacaatta taaaaaagga ggtgctgctt
     5521 atgaaagcta tccatatttc tttgcttttt ttcgctagtg cattgatttt atttgctatt
     5581 catctttgtt cccagcctta tatcaataac aacggaatat tagtggaacc agcattcttt
     5641 tgcttaccac tcggcttttt gtcccttctt gcctccgcag gcttcggatt tgttgctttt
     5701 tttaaacgat caaaacaaca aatctgactt ataaaattta cgtaaaagag atcgtgacaa
     5761 taatcgtgtg atattcccaa atttcgaata aaaggtgccc cttgccatct ctaactcctc
     5821 agtcacaagt tacaatattc ataaaccatg aaaagcttgt ttattgaaat tgctccttgt
     5881 gacttggagc taagtgacag attacaacct cttttgcatc ataagacttt actccttgaa
     5941 aaacattact aacttttgat atgtttcttg cgcttgttta ttgctgaaat caaactgata
     6001 ttcatggttc aaaacagcat ttttctccgc ataatctact tttgtgactt tcacccccgc
     6061 tttctcaaat acagaagtta cttcttccat ttgtttcgta aacgtatttg tatttccatc
     6121 cgttaagaat gtgttttgcg tccaacgatc cgcatgtctg accaaggcta aacttttgac
     6181 cttctctgat tgttcaaagt ccttattatc aaagtaagcc catccacatt tttcataaag
     6241 aaagctagag attttatcac ttacttgagt aagtgcagaa ggatccaaca gaccagacaa
     6301 agaaataaac ttcgtaatct gcttgttctc caaagtcgga tcaagatgat cagctttttt
     6361 aatttcttca ttttgaagtg ctaacaaata ttctccacta atttgtgcac ctgccgaatt
     6421 tccaccaatc gaaatattcg accaatctgc ttgatctttt atctcttttt tagctgcttg
     6481 aatggcttcg ttcaattgga taactggtgt aggatgtttt gcttccggtg atcgttcata
     6541 atctatattt acgatgattt gctgcgtgtc tgaacataga tattccaaat aatcacgaca
     6601 atcattttta tcccctccta catatgcgcc tccatgcatc cagaaaagaa tcggtaattt
     6661 tttcttttcc actttcggtg tgtagatatc catattatta tttttgtact ttgaaggata
     6721 ggatatttct ttttttatat cgatttgttc gattttttgc tggaaatcat ctggtcgggc
     6781 atatacttgt tctttttcac ttgtgtcaaa ttgttttcta acaagcaagc taatcggctt
     6841 tggtgtgatt tgattaatca aaaatacagt gactaaaata actacgatga taactggtac
     6901 tgcaatcact attcgcttga accatttcat tcatttaccc tctctttctt cgccaaatcc
     6961 atgtgataat cgtgctaaca gataaaaatc cacctgaata aatgagaagc gaatgtttct
     7021 tttctccagt tttcggcaac attctttttt ttgcatctgt ctttttttgt actttcactg
     7081 tcatctgaat cggttgcgta tcatcacttg attgatcctc tcgaggttca ttctttccct
     7141 tattgtctgc attctctgtc ggatcttgct tttttggtgg agctactggg atttttttgt
     7201 aatagaaaat aatagttggt atcgtctcat taaaaatccc ttcagtcggt ccttcaacat
     7261 ttgctaattc gtatccttcg aatgtctttt gctctgtcat ataattttct ccataagctc
     7321 cgtaaagctg gatttcgtcc tggtctttga gtagactttt attgttttca tccacatact
     7381 ttacgtttat ctgatcatgg aacactactt tcaaaaagtc cgttacatgt ttcgtgtagg
     7441 cagcatggtc aacttcctgt gcctttccat gccctgctcc ttctactaat aaaagatctt
     7501 tataccctcc tgataactca tataattttt gcgcgttaga cacaggtact acatcatctg
     7561 ctgttccatg gataatcaat ttaggcaatg aatctgacat tccaatcgta ggtagagcag
     7621 cttttgtatc caaatgcatc tcctgatcaa aatagtattg tttcaaaagg cccataaata
     7681 aatcttcatg ctcttgatcc ccaatgatgt ctaactgatt ttttatggca tccggtagtg
     7741 cgggggctac tgtctggctg tacgtaaaac gtagttgttc atcaattgat gcaaatccgc
     7801 aattttcaat aattcctttg acattgacag gaatatcttt cgctaataca gacatcatcg
     7861 tagctgctcc catcgaacca ccataaagta aaatcttttg agatggccgc tctcgaactt
     7921 cttgatttat ccagtaaagg acgtcatctg actcatattg tccataggtc acataatcgc
     7981 ctccgctatt accagtcgct ctggaatcaa caaataataa attatacccg gccttataaa
     8041 aatcattgta ttcttctgta acgatcccgt tattccaatt ccctcgaaat ccgccatgga
     8101 tcatgactgt tttatctgaa ccttgatcga cataatatgc atatacatcc atcattttgc
     8161 catcttgttt gtttagtaca gtttgatgaa gttgttttgt atttggatag aagcctgtgt
     8221 tttctgtagg cgttgtccca tcatctgtac ctccaagcat cgacatcaac acactgtttt
     8281 ttgcaaaagc gatatcgtac aatagataag tagcaatcag atgtttgata atctctttat
     8341 ctacaccata atcattaaca gcaagctcag tgactaataa ctctattaat tttgacttga
     8401 tgtcttctgt tggtccatta agtatttctg tcatctgttt accgaagtaa ttcaaatatt
     8461 ctttaccatt gaaattttca cctttaccga tatcatcatt ttctgtccca ttctctttgt
     8521 cacttacttt agcagaagag gattcgtcgt ttgacatttt tgtagctgtt gcttcttctg
     8581 tttgttggtt atctgtggta gcggtcgttt cttgatctgt gctagtaaca gatgtctcaa
     8641 ccgttgtttc agtatttgtt tctgtttgtg aagtactcga tttcgtttca tttccagcat
     8701 cagtagtttc tgtggtttct acctcccgag attccgattc ggaagaaatg ctctctccat
     8761 atactgtcca ttgcgggacg cttgtactta cagcaaataa gatgaccaac gctcccttta
     8821 atacttgttt tgttctcaag ctattcactc ctttttatgt ttctaggaga attatatgta
     8881 aacgcaaaca ttttttatac aaaaaataaa tggtttatcc cataaaaata gaacaggatt
     8941 attttctcat tttacgtaat aaagcagaat ggataaacca gtatccattc tgcttttttt
     9001 aaacgaagaa acaacttatt gctccaaaaa tgtcagaaat cgtttatccc aaattttctc
     9061 gtaaaaagcg attgtttcct ttgctttcat aaaaggatta tcataagttg tcgttgctcc
     9121 tctacacatc ataagctggt atcctaatcc atgagcaaac ttcacagtcg tatctataca
     9181 atactctgct tgtgccccac ataattcgat cgaatgacag tccaattcag ttaataaaac
     9241 actcaaatta gtcttataaa atgaattcgc atgggttttt ctcacaaaat aactgtgctc
     9301 aggaatagat aattccgaca atagctccca tggttttgtt tgtggcacta attgagcatc
     9361 ttcgtgttga acgaaaataa ctggtttccc aatcgtttcg tatgttttga ttcttttatt
     9421 cactaatgct gtcactgttt ctaattcgtg tatcggcgaa gaatcaaaac ataccccttt
     9481 ttgtaaatcg atcactacta ttgcgtcggc tgtgtttgac atacttgtgc cttctttctt
     9541 ttttcttgat ttaatagtat ttcttatcta gctagttcca ttatacgtga caacattttc
     9601 ttattttaca cctctaaatg gcacttttcg actatttctt catgttatta tttcataaat
     9661 acttagctat tggaggaatg tatgatgatt aaattgtata caggttctgg ctgctcgtct
     9721 tcaagacgcg caaaacgttg gcttatcgtc catgatatac cgtttatcga acagaactta
     9781 attcgtcaac cactaaccaa aaatgaattt atccacttac taaaattgac aaacaacggc
     9841 gtgaccgaaa tgctctctac tcattctatt agttataaaa atcttgttca cagaatagat
     9901 gaactcagtt tgagtgaact atatattgag attcgtacat ccccttcttt attgaaaaaa
     9961 ccgattatct acgaccaatc tgcaaaactt ttgactggat ttagcgaaga taaaatcagg
    10021 atgttccttt ctaaaactaa aagaaagcaa gagctcaacg aactcttgct ttctggtcat
    10081 cttgtcgatt ttaaagaaaa taatcttttt gcaatgtctt aattttggca taaacaatct
    10141 gcttttctta attaacgaaa tccaattttt ccaatatgga tctatttttc tcattcctga
    10201 tttttatgat ttcagctttc agacgcgccc aatcattttt tgtaggttgt ccattccagt
    10261 aaaatatctg tgtattcgtt tgatcatatg cctttttgtc gataggataa tcgctaatga
    10321 caatatcagg taactgatca gcggatgcac tatattttat tgggcgttca gtcatagata
    10381 atatcctttt ctttgcccat aattcctgtg ttttaccata ctttgattga atatagaata
    10441 tgacaggttg ttcgtgtttt ataaaaatat ccctgactaa catacagtat tgaaaaatca
    10501 accgtctgtt cttttcataa taagtattaa gctctggaat tctgcgagct accccactaa
    10561 aaaactgttg catgattgga tacatcactg gaaatatatg ctgaaaatct ctgtcttctg
    10621 ctgattttcc aaaagcatcc accttctttt ttgtcccaaa aacccttgaa tacaaatgga
    10681 tcattgccaa attgacatat agataatttt tttctgaagt tgtaaaacaa atcttgaagt
    10741 ttttttcaaa attttctaca atagacgatt caatccagcc ccaactttct tgtactttat
    10801 ctggagtatc caacaaatct tcttccaaat aggtgttcat tacaccaaac ataaaataaa
    10861 ggtaagcttg ctctgttgga gtgatgtgat tcatcgacca gaagtttgct tcaaaaaaag
    10921 gctctagtat gtaatgcgta aactcttctt ttgttatcaa tggatgcaca aatttgttca
    10981 tctcttctgg gacatacgta atcgagtggc cttgtttcat tcgttgcaac gaaattctta
    11041 gtaggctgat ccatttcttt ctatctatac tacgcgtata tggcgcatgt ttcgcaaatt
    11101 tttctaatag ttgacgttta ttttttatac ttgataatat atcagaatga ttttcgtcga
    11161 atgactgcca atacatcaag tgaaaaaagt atcggatacg gtattcttct ccttctatcg
    11221 gattaccttt tttcaagctg caagataaat gatagttttt caaaatagta ttaagttctc
    11281 ttaattttct ttgaatcgta cgcaaactta tataattttt tgactaagat tttctaagga
    11341 ttgataagta cctttgtaaa gtgaatccag taaaatataa ccaatcgttc cctctaaaag
    11401 tatagaataa actttactca gtaaaaactg agaagaaaac tcgactttta tcatcttgtt
    11461 ttctgaaaga aaagataatt tatattctgg atacctttcg caaaacgatt ctgcttgttg
    11521 aatcaccgaa ttcatcttag ccagggtgta gtttagatct aaagcgatat ccttcaccac
    11581 atataatttc tcgtctcttt cataacaata gttcaaaaat tgatatactt gcctttcatt
    11641 gatatcaata aattcttcaa acaaagtaca tactcctttt tatctattat ttagacttat
    11701 tccgacagct acatgaataa cgtacaaata gattcgttac tgatttttca gagatactac
    11761 catgcgcagt gtgcattgtc aattattctt gctcttattt tccatttgtg ttcctgttat
    11821 ttcctgtttc tcaaatatgt tagtaaacaa aaatagatct ggcaaagcta caacttcgcc
    11881 aggcaataca gcactctcga atgaaatatt cactcaaaaa tctatcgttt tattcaattt
    11941 tagatctgtt gcttttattc tttatttcac tcgatggaag agagaacgaa aatagcttgc
    12001 tcctacaatc aaaatgagta acacacccat ccatgtaatt agcttgttca aggttctact
    12061 accagtttct ggtaaatcgc tttttctatt atctgtttct ttcgcttttt cttgatgatc
    12121 aattccacga gaaacaaaat caggctgttt tagcacactt tttaggttgc tccctgcatt
    12181 tctcttttgt tccttagttg gtatgatagg taccaaatca agttcattat ttacttttcc
    12241 tgtgctgctt tcgctgctcg tgcttcctgt gctactttca ctactcgtac tctccgtact
    12301 gctttcgctg ctcgtgtttt ctgtgctact ttcactgctc gtactctctg tactgctttc
    12361 accgctcgtg ttttctgtac tgctttcact acttgtgcta tccgtactgc ttggcggtcc
    12421 aacaactgtc caactgcttg gtttcaaatt ctccgtgatc gtcatctgtc catcataaaa
    12481 aacaatcaaa tcaactttat ctttactctt gatctcatca atcgatagtt ctgcagaaat
    12541 cattattgta tactcaatac cagcggtcca ttgtacgtct tttaaataaa cttccccaat
    12601 aactttttct gaacttccat taccatccca accatatgtt agaacagcat gtacatcact
    12661 agcattcacg cttttgtttg gtttgactgg aatagtaatg acttgttgtg tcatgtcata
    12721 aacaatccga tcagttttca cagtaaatga aagattctca tttgcccgtt catttgcaga
    12781 agtactgatt ccaatcattg ctgcaattat actcagccca agaataacaa ataatacggt
    12841 cgctgttttc ttcatttcta tcactctcca tataattacc ttctatttga taaaggaatt
    12901 atataaaatg aaaatgatga gaacacgaca gtcagttgtg aaaatctaac aaaagatgtc
    12961 gtgtattcgc ttgaatttgt ttactttttc gtttaatcaa tgacagactt aaaaaagcaa
    13021 gaccgatatc agccttgctt tcttcatctt ttattgataa acagcagtgt atttcttcat
    13081 ccgctttgtt ttatatgcat agagtaacaa accaacaatc aagactaaca agaataatgt
    13141 agttgatata gatgcttcag ccccaaagtt tcccccagta attattgtat tttgcgattg
    13201 gatcagagtg gagaaaaaac cttgttcttg cgttccgctg actggtatac ccaaaatagc
    13261 tccttgtgtc caattccaag taatatgagc accaatagcc gtaaataaac ttcctgtact
    13321 gtagataagt gcgctgaaaa agcaacctgc taaaaagata ttgaaaactg ccagaaatgt
    13381 catgttagga ttcaatccgt gcaaaagagc aaataatgca gcagatccaa tcattgctat
    13441 taacggacca aatctaagca tctgatgctg aaaaaagcca cggaataaaa gctcttctga
    13501 tgcccccact gcaataaata aaataaaact cgttatcagc ggcacaatgt ttgcgtttcc
    13561 tgaatctaac cgatacgccc ccgtcaaata taatggacta gtaataagca gaaacactcc
    13621 aattccaaca acgagacctc ccgctaaata cccccagtct tttcctcgaa cagaaacacc
    13681 ataatcttct attctttttc cttcgacctt actagcaaga aataaagcta gtaaaaaaac
    13741 agctaaatgt ccgaccgtac cggcaattgc tccaatccat tcactatttc caataaacat
    13801 atccgcaagt gcattattga caagaattcc taaaacaaaa ccaactaaga ctattaaaac
    13861 agatccaatc aaccgaataa tcctgatcat ctttcatccc tcctttatat taagtttaac
    13921 aacccttttc tttcttgtct cgtgaaaact atgtaaatgt tctccatcat agagagaata
    13981 gatttttacg aactaagaat atctacagca accttacgaa aatgaaagac tgtctcccta
    14041 attcttctgt tagactgttt ttaataagga aaggatggga aattttttga aaaaacaact
    14101 actaattatg tgcctttcag catgtgcaat tttactattc tcaggttgta gcaagtccaa
    14161 tgaaacgatt gcaa
//
LOCUS       DACDLM010000067        14115 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.069, whole genome shotgun sequence.
ACCESSION   DACDLM010000067 DACDLM010000000
VERSION     DACDLM010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14115
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.069"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..554)
                     /locus_tag="IV356_002192"
     CDS             complement(<1..554)
                     /locus_tag="IV356_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HAP9015857.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGA"
     gene            complement(570..1049)
                     /locus_tag="IV356_002193"
     CDS             complement(570..1049)
                     /locus_tag="IV356_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HAP9015858.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKARLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(1055..2079)
                     /locus_tag="IV356_002194"
                     /pseudo
     CDS             complement(1055..2079)
                     /locus_tag="IV356_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
     gene            complement(2096..3202)
                     /locus_tag="IV356_002195"
     CDS             complement(2096..3202)
                     /locus_tag="IV356_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAP9015859.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(3431..6028)
                     /gene="adhE"
                     /locus_tag="IV356_002196"
                     /gene_synonym="adhC"
     CDS             complement(3431..6028)
                     /gene="adhE"
                     /locus_tag="IV356_002196"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HAP9015860.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(6333..6713)
                     /gene="yajC"
                     /locus_tag="IV356_002197"
     CDS             complement(6333..6713)
                     /gene="yajC"
                     /locus_tag="IV356_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HAP9015861.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(6810..7955)
                     /gene="tgt"
                     /locus_tag="IV356_002198"
     CDS             complement(6810..7955)
                     /gene="tgt"
                     /locus_tag="IV356_002198"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010769586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HAP9015862.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            8173..8871
                     /locus_tag="IV356_002199"
     CDS             8173..8871
                     /locus_tag="IV356_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAP9015863.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(9039..11678)
                     /locus_tag="IV356_002200"
     CDS             complement(9039..11678)
                     /locus_tag="IV356_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAP9015864.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(12297..13328)
                     /gene="queA"
                     /locus_tag="IV356_002201"
     CDS             complement(12297..13328)
                     /gene="queA"
                     /locus_tag="IV356_002201"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HAP9015865.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            13521..>14115
                     /locus_tag="IV356_002202"
     CDS             13521..>14115
                     /locus_tag="IV356_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005232177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP9015866.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDE"
BASE COUNT         3957 a         3095 c         2543 g         4520 t
ORIGIN      
        1 gcgcctacga gataacctcc cataaacaaa gcagagatcg aagcaccacc agcaacaagt
       61 gaatacatga taaaagcagt acttggagga atgaccatac ctgtcggagc tgacgcgata
      121 ttgaccgctg tcgcaaactt ccggtcatat ccttcttcca cttgctgagg gatcaacact
      181 ccaccaatcg cggtagaagc ggcaatggcc gagctagaga tggaaccaaa taaagcattc
      241 cctaacacat tcgtatgagc caaagccccc ggcacgcgcc cgacgaacaa catcgcaaaa
      301 tccactagtt tcttagctat ccctccatta ttcatgataa tgcccgagag aacgaaaaac
      361 ggaatagcga tcagcgaaaa actattgata cttcccacca ttttttgagc tgaactaaaa
      421 gcagaaacat caaacggtat aactaacaat aaagtcatca tcgatgagaa tgcaatactt
      481 atagcaatcg gcatccctaa tacaagcaac acaacaaata caaaaaataa cactaatccg
      541 gcttctattg ccattttatt cctccatttt tatatttttt cttgaattgc tggcttgttg
      601 cttaatgtat cgattagatt gatcaggcta tagataatga tgagtacccc cgatacaggt
      661 actgacagat aaacatatcc cataggaata cttaaagaag gcgagatctg ccccattgtc
      721 aatgtgacag cattccatcc gccatacacc atgatcatcg cagcaaatac cagaaataaa
      781 ctttgaacaa caacttctaa aattttactt tttttgccag ttaatttttc acttaaaacc
      841 gttacggcta aacgtgcttt ttgtcccaca acatacgcgg aagacaacat ggcaaaccag
      901 acaagaccga atcgaacaag ctcttccgtg accgtatttg gatttcctaa aaccgttctg
      961 gaaaatactt gccataaaac aacagcgacc atcccaacaa gcaaaacagc tcccaggatc
     1021 tctaatacct tgtttaaaat cattttcatt acagctacgc tccttgctct tggatctttt
     1081 gataaaggtc tttgtaggta ggatcgtttt tgaatatatc atgaagtggg gcaactgcct
     1141 ctcgaaacgg tgtattatct acatcattga attggactcc atgttcttct tgtgctaaag
     1201 ctttttcttc ttcaattgct tttgcaaaag cttcaatttc aaaaaccgtt gattctttcg
     1261 ctgcttcttc aatggctttt tcctgttcat cagttagctg ttctttgatg gcatcattca
     1321 tgatgatgat atctggcaca cgtgtatgct catcatagga atagtattta gctaccccgc
     1381 catgtccagc tgtatacaag acaaattcat tgttttctga tccgttgatc aaattggatt
     1441 gaagagacgt gtacacttca tcacttccca taggtacggg cgaaccgcct aaaagctcta
     1501 ccattttgat agcggtttcg ctttgcatca cacggatctt ctttcccttc aaatcttccg
     1561 gcgtatggat cggaccgtct accatataaa agctgcgctg accagaatca taataggtca
     1621 atccggtaaa tcctaaattt ttggtcgatt ggtagattgg ctccattatt tcttcattat
     1681 ccatcacctt aaagaaatgt tcttcatcat tgaatagata aggaacggaa aaaatcgaat
     1741 aatctttaga gaaactttcc aacgctgagg cacttacttt tgtgaaatct actgctcctg
     1801 actgtgtcaa ttcgatcagt tcacgttctc cacccagttg tccatctggg aaatactgga
     1861 tctgtacgga accatctgtt ttttctttta ctaaacgccc aaattcattc attgcatcaa
     1921 ttactggctg ttgcttgcat aagcaaagcg caaggtaact atctcattta cgtctgcatc
     1981 tgcgacagtt gccacactag aattatttcc gcagccgctt agacctagca gacctaggct
     2041 aagcgaactt gctgcaaaca gcagtgatgt ttttttcata tgggtttcct ttcttttaac
     2101 aataagagac gagcaattct gtcaaacaaa gcaccgttaa cgactgtcca taaggcattg
     2161 ctgtgattcc gatattccga taaaaatcta aactgtcccc cattcctgtc ccgattgaaa
     2221 cgttttgaac ttctcctttt tcatcgattt gttcaagcaa tccttggata gcacgataag
     2281 cgacttcttt atattcttgt ggtaaataac gtttatggac cgctttcaaa ataccgtaag
     2341 caaatcctgc agttgcagaa gattctacgt aagaagaagg atcatccaac aacgtatgcc
     2401 ataaaccgct ttcagactga taagttttta atgcacgcac ttgtgcttca agtgtttcga
     2461 tcaataattt gcgcaatgca tcttctttcg ataattctaa gatttcaatg atctctggaa
     2521 tagcaatcgt caaccagcag tttccacgag cccaaaatgc ttcggcatag ttatgatttc
     2581 cttcaaacgt ccagccgtga taccacaatc ctgttcgttt atccatcaag tatttgatat
     2641 ggatcataaa ctggtaacga gcttcttcta aatattctgg gcgattcaac agtttcccga
     2701 tttttgccaa aggaagcact gtcatcatca atgtatcgtc ccacaactga ttcttatttt
     2761 ccggtccata tgtggcatgc tgtaacccgt cttcatttgt ccgaggcatg tcattcatga
     2821 cccattctgc ccattgttct aaataaggca aatagcgtga atctttcgtg tcttcataca
     2881 agtaagccat agtcaatagc ggtgccattg tattgacgtt tttgggcgga gcgccttctt
     2941 ccatacgatc ctcaaaccat tcattgacca cttgataagc gcgaggattt tttgtcatct
     3001 ggtaattttt ataaatacca tatagaccga caccttgtgg ccaattccac actgtccagc
     3061 ttttgtcatc tactttcagt ccatcaaagt ccaacaaaaa ttcaccatta tcgtctttga
     3121 tcgttgtcag gttttcaacg agcaggtcaa ttttttcttt cactaattct ttaggtacaa
     3181 aaatctcttc tttaataatc atctttacgc caccttttta aacgctttca ttttatatcc
     3241 ttaatatagc agtaataccg tccactataa atatcgcttt ttgaacaaaa actgtctaaa
     3301 attgacctaa atgttaaata acaaaagtaa ctttcagtta cttggaaatt aaaaaaagaa
     3361 cttggagaaa caacgttttc caagttcttt ttcatctatt ttcttatctt ttttctacgc
     3421 tttcttttgc ttatccgttg taagcatcaa tgatgatctg tttcaattca gagatcaatg
     3481 gttctttcgg attagctgtc gtacattggt cttcgtaagc taattcagcc atacggtcta
     3541 cggttgtatc tagtgtttct tgtgtgactc cttgagcttt tagactcatg ttgatgccga
     3601 cagattttcc taattcataa acagccgttg ctaaagcttc gactaattcc tctgttgttt
     3661 cgcctttcag acctaagaat tttgcgatat ctgcgtaatc tgtatctgca cggaaatagt
     3721 catatttagg gaacatcgca tgtttttgtg gatcttttgc attatagcgg ataatatgcg
     3781 gtaaaagaat cgcatttgtc cgtccatgag ggatcccgta ttccccgccg attttatgtg
     3841 cgactgagtg acaaatacct aggaatgcgt tagcaaacgc cataccagcc attgtagaag
     3901 cgttgtgcat tttttcacgt gattccatat caggtgtttt tactgatttt tctaaatagt
     3961 caaagactaa cttgattgct tgtaggctca atccacgtgt ataatctgaa gccatgactg
     4021 aaacatagga ttcgattgca tgtgttaaca catccatccc ggtatctgct gtgacagatg
     4081 ctggaactga catgacgaat tgaggatcga cgattgcgac atctggcgtc aatgcataat
     4141 ctgctaacgg atatttcaca tgtgtttcac tgtcagtgat gaccgcaaat ggcgttactt
     4201 cagaaccagt ccctgatgtt gtcgggatac atacgaattg tgttttttct ggtttgtcga
     4261 tcttatatgt ccgtttacgg atatccaaga atttttgttt tgcaccaaag aaagatgtgt
     4321 ctgggtgttc atagaacatc cacattccct tagctgcgtc cattgcagaa ccgcctccaa
     4381 gagcgattac tgtatctggc ttgaagtctg ccatcagttt cgttcctgcg tatacggtat
     4441 ttgtcgatgg gttcggttca acatctgaga agacttcgat cttcacatca tttttacgtc
     4501 gtgccaatac ttcacgaact gtatcgcagt aaccgaattg gaccatacca gggtcacaaa
     4561 cgatcatgac acgttcaacg ttttccattt tctctaagta caatagagag ttcttttcaa
     4621 agaagatttt tggcggtaat ttgaaccatt gcatgttatt tctccgtttc gctacagttt
     4681 tgacattgat taagtttaca gcagagacgt tacgagaaac agagttctta ccataagaac
     4741 cgcatcccaa agtcaatgac ggaatcattt cgttatagat atcaccgatg ccgccttctg
     4801 cagatggtgt attcactaaa atacgacaag ctttcattcg aagaccgaat ttgacatgca
     4861 actcttcgtt ttctgaatgg ataactgctg tatgtcctaa tcctccaaga ttcaacatac
     4921 cttcacacaa atcaaacgca tggtccgtgt tgttagcttt gatcatggca agaactggag
     4981 aaagtttttc tcttgatagc ggataatctg ggcctacgcc ttccaattca gcaatcagca
     5041 ttttcgttcc ttttggtaca ctgattcctg ccaattttgc gatttccatc gcagaatgtc
     5101 caacgattga tggattgacc gcatattttc cttcgttcat cactgcatct tctaattttt
     5161 gcaattcatc tggttttacg atataaactt ggtgtgcttg gaattctgct tttactgctg
     5221 catagatttc tttatccacg atcacagctt gttcagaagc acaaatcatt ccattatcaa
     5281 atgttttcga aacgatcaaa tcgttcactg cacgtttaat ttttgctgtt ttttcaatat
     5341 aagctggtac gttacctgga cctacaccta aagctggttt tcctgtagag taagcagact
     5401 tgaccattcc agctccacct gtcgctaaga cgatcgcgat acctggatgg ttcattagca
     5461 tagaagtcgc ttcgatcgaa ggatgttcga tccattggat acaattttca ggagctccgg
     5521 cagcgatagc agcatcacgt accactcgtg ctgcttctgc agaagatttt tgggcacttg
     5581 gatggaaagc aaaaacgatt ggatttcttg ttttcaacgc gatcattgat ttgaaaatcg
     5641 ttgtggaagt cggattcgtt gttggagtta ctccgcaaac cacaccgact ggttcagcaa
     5701 tttcaatcaa ccctttttgg acatcttcat tgatcacacc aactgtttta tcatgtttga
     5761 tattatgcca aatatattcg gacgcataca tatttttgat tgctttatct tcgtaaacac
     5821 cgcggcctgt ttcctctaca gccatcttcg ctaatggcat atgttgatcc aaagctgcca
     5881 ttgccatttc atgcacgata tggtctactt tttcttgatc aaagctttcc atttctttca
     5941 atgctgcatt tgctttttct gccaaatcat caatcattgc ttgtacgtca attgtcttcg
     6001 ttttttcttt ttctattact ttagccatca ttatcctcct aatgggtcat ggttatttgt
     6061 taaataattc acatgtatat catacaatat ttatttttct atgtaaacac ttttttgtga
     6121 tttttttcac agttattttt aaatataaaa ttgctttatt tacaggtgtt tgtatagaaa
     6181 aatatataaa gttatttatt attatttata tgacacaccc gattattcaa tattgagcaa
     6241 tatatcccat gctcttatct ctttcttttt tgaataaaaa atgaggtagg acatctttct
     6301 gccctacctc gtctttaaat aagctttgat acttattttt cttccttctc ttctgtctct
     6361 tccagcgttt ctgttgtttc agtttttact tcaactgtct cagctggttc ttctgttgtt
     6421 tcaacagtag tcgttgcatc atttgttacg acagtccctg gtttgaccgt tttgattgct
     6481 gcacgatcgt actcaaggaa gatcccttcg cagtctaaaa caactgtccg tttgtcattg
     6541 tcgatttctg aaacaactcc atgtaatccg ccgatcgtta cgactgaatc acctggtttc
     6601 atgctatcta acaagttttg acgttcttgc tgttgtttct tttgcgaacg tgacataaaa
     6661 aaccacattg ctaatagcgc gataaacatc acaagcattg gtaatgttcc catttttttc
     6721 acctcactaa ttctgtatct acaaaaaaca ctttagcaga aaaatgctga taacactagt
     6781 tttttactta atttttaaaa gattttcctt tagaagcttt ttgcgttttc tttattgaac
     6841 ccgtattctt caaaaaaggc ttctctaaat tcaagcaaat tatcatccat gattgcttga
     6901 cgtacttgtt tcattagatt caacaagaag tataaattgt ggtaagaagt caaacgaatc
     6961 ccaaatgttt catcacattt gatcaaatgg cggatatagg cacgtgtata gtttttacat
     7021 gtataacaat cacatttctc atcaattgga cggaaatcat gggcatattt cgcatttttc
     7081 actactagac ggccttgaga agtcatacat gtgccatttc gagcgattcg agtaggcaag
     7141 acacagtcaa acatgtctac tccacggata acaccatcga tcaatgaatc agcagcaccg
     7201 acacccatca agtaacgtgg tttgttttcg gggatcaacg gtgtagtgaa ttctaataca
     7261 cgattcattt ctgatttagg ttccccgaca gataacccgc cgattgagta accagggaaa
     7321 tccatcccga ctagatcttt cgcgctttga cgacgaagat cttcaaaccc tgctccttgg
     7381 atgattccaa ataatccttg acggtctgga ttagcatgag ctttcaatcc tcgttctgcc
     7441 catcgagacg tacgttctac tgattttttc acgtagtcgt aactttcatc gaatggtgga
     7501 cattcgtcaa aactcatcat gatatcagag cccaatttat tttggatgtt gattgctttt
     7561 tctggtgata aaaacatacg cgaaccgttc aagtgatttt tgaaatgcac gccttcttct
     7621 tcgatattcc gcatatcact taatgaaaaa acttgaaagc cgcctgaatc tgttaaaatc
     7681 ggttgatccc agttcataaa tttatgcagt ccgccagctt cttctactaa gtcttcacca
     7741 gggcgtagcc ataaatgata tgtattactt aaaataacgc cagcacccat ttctttcaac
     7801 tcttctgggg acattgtttt tactgtagct aatgttccta ctggcatgaa cattggtgtg
     7861 gggaaagttc cgtgtggcgt gatcaattcc cctaaacgcg cgccagtatg tttttctttc
     7921 ttgattaaac gatagcgaat ggcaggttgc gtcattcatt tccctacttt ctatataaaa
     7981 tatcttgaca actcccacca tcataatcgt ttcaagtgct ttttgcaagt tccctcggct
     8041 tccttctact ttatttaata ttcttttttt tatccttttt ttatgaataa caaaaaaaag
     8101 aaaaacatta tgacagaaat attttttgat acatggtata ttggtgttat taaagaaaag
     8161 gagggaaaaa tcatgcaatc ttctgcagaa ttaaaacgcc aagcaaaaga gagtctaaaa
     8221 ggacgttggg gacaagctgt tttactaaat ctaatcccta cattgattgg tattgctact
     8281 attcttctta ttatgattcc tattatcttg tttgccacca ccatatatga tggatcagcg
     8341 agcgtctcag aagcgacaac ttcaggaggc ggtagttcag gaggcggtgg cggaattatt
     8401 tccagcatca ttagcgcttt gttcatgagc ggtatttctt ggacttatct tgatatttta
     8461 cgtggacaaa aagatcagat cgaaccattc aaagatgcat ttcgtggatt caaaggtttg
     8521 tttatcggcg gagtgatcag cttagctgtg ctgatctcga tctttacaac attatggggt
     8581 ttgctattag ttattcctgg aatcattaaa agctattctt attctcaaag ctattttatt
     8641 tactacgata tcgtccaaga aacaggacaa acacctaaag tactggatac gatcactgca
     8701 agtcgaaaat tgatggatgg ttataaagga caacttttct ggttagatct ttcatttatc
     8761 ggctggcata tcttagcatt agcaactgct ggtattggtt atctatggct cagcccatac
     8821 atttctgcaa caaaagcagc attttatgaa caattgccaa aagatattta aaagagagtg
     8881 tgacttgtga ccgagggggt ggcaggagaa caccgtttat cgagaggcag taaaagaaac
     8941 attcagccca ttagcaaaaa ggaggtgtga caacattcat gtcacacctc ctttttgtat
     9001 agttccagta aaaagaaaat caacttagaa acagttaatc attcctcttc ttctgcttcc
     9061 ggtaatcgat ggaacttgat cagttcattc accgcgattg gtacgataga taaaatccct
     9121 accaagaacc agtgattcaa actgatgtgt actaggccga atagttcttg cgtaaatggc
     9181 agcaaagcaa cagccgttgt aatagctaat gccagtaacg ccatttctac caaagcttta
     9241 ttggtcgcta aattgacttt gaagatcgat tggctgctgc gtacattgaa cacatgcaga
     9301 atcgatgaat aagctaagat caagaatgca acagtttgac cgacatgctg acttgcgtct
     9361 acccatgggc tgatagtatc gacataacta cctaaataat aaccaaacaa ggttacgatg
     9421 gtgaagaccc ctgcatttat ggcaattttt tgcaataaac ctcgagcaaa gatcccttca
     9481 tttttcggaa tgggtggctg atccatgatg ccgtgttccg ctggctctct tcctaaagca
     9541 aatcctggaa gtccatcagc aactacattg acaaacagta gttgcacagc tgtaaatggt
     9601 gctccccatc ctaacagcat cgcaatcaaa acaataaaga tctccgaaat attacagctt
     9661 agcaaaaagt tgatagcttt acgaatattc tgataaaccg aacgtccttg actgacagcg
     9721 tctacgatcg tcgcaaagtt gtcatccgtc aaaatcatat ctgcggcact ttgcgccaca
     9781 tctgttcctg tgatccccat ggcacaccca acgttacttg ctttcaacgc tggtgcatca
     9841 ttcacaccat ccccagtcat cgctacgact gcacccgtac gttgccaaga tttgacgatc
     9901 cggatcttgt cttctggcgt tacccgagca tagacagaga gagctttgac acgcgcatct
     9961 aattcttcgt ctgataattg atgcagttct gatcctgaaa gtgcttctga cggatcattc
    10021 aagataccta attctttcgc tatggcactg gcagtcacca catgatctcc agtgatcatg
    10081 actgttttga tgccagcctt tttcgctcgc ttgattgctc ctttactttc tggacgtggt
    10141 ggatcgatca ttccgatcag accaatcaaa cgtaagtctt tttccagtgc ttcagaagaa
    10201 atatcttgcg gttcttcgtc ataagtagca taaccaacag caatcactct cagtgcccgt
    10261 ttaccaaagc gatcattaac gatcgccgct tgttctacat cgcctgaact aaagcgcgga
    10321 gcaagaacat cgaatgctcc tttggtgatt gagatgtatt tttcgcccat ttggtgaact
    10381 gttgtcatca tttttcgttc agaatcaaaa ggaagctcgt ttactcgtgg atatttttct
    10441 tctaattctg cctttgtatg ataattctct tcaacagccc ttacgatggc tacttctgtt
    10501 ggattacctt tgataacaag gtcgtcatct tcttgctcga ccgtcacatc tgtacatagt
    10561 gcagccattt tcaatatttc catcgcgctg ttcgtcattg aatcttcgat attcgttact
    10621 tcatcttctt tgctccatac ccggcggacg cgcatttcat tttgtgtcag cgttcctgtt
    10681 ttgtctgagc agataacatt agcggttcct agcgtttcaa ctgctggcaa ctgtcggatg
    10741 atcgcatgtt tcctcgccat cttctgcaca ccgtatgcaa gtgtcaacgt aacaataaca
    10801 gtcaaggttt ccggtacagc tgcaacagcc aaggaaatcg aagtcatgaa catctcaagg
    10861 agtggttctc cttgcagttc accaatcaca aatactaaag ccgcagccgc taaagcgatc
    10921 atactgattc gtttgcctag ctgattcaat cggacctgta aaggtgtttt ttgcatagta
    10981 ttttcgttca aaagatccgc gatcttaccc atttctgtag ccatgccaat ggcagtgacg
    11041 atcgctttcc cacgacctgc agcaaccgta catcctttaa ataccatatt aagttggtca
    11101 cctaatgact catcttcttc agcaataaat gctgcatctt tttcaactgc ttcactttct
    11161 ccagtcaacg ccgattcttc tacacgtaat tgtgatgctt cgatcaaacg ggcatcggca
    11221 gaaatagcat caccggactc taaaacaaga atatcaccca ctaccagttg ctctgactca
    11281 acagtggtca ctttgccgtc tcgtatgaca gttgccgttt gtttattcat atcttgcaag
    11341 gattccagtg ctttttctgc gtttccttct tggacaatcg ccaataccga gttgatcaca
    11401 acgatagcga tgatcagcag tccttcaaat aaatccccat gttctgtagc aaatgcggta
    11461 taaaaggaaa tcaccgctgc tacaagaagg atgatcgttg taaaatcgga caagcttcga
    11521 aagaattttt tgatcatcga ttctttcggc gcctcatcga atttattcaa tccctgcttt
    11581 tttcgccgtt catccacttc ttgtgaagac aacccagtat ctggatctgc ttctgttacc
    11641 ttctttactt cttctattgt ctgcttgtat tcttccatcc tattcctcct ttaaaatctt
    11701 cgtacaaaaa aaggtactta ttttactata acatcctttt tttatttact tcaaataaag
    11761 ggcttatcga ttatttgtta agaaagcgta aaatttaaag tgcttatatt tgcaaacgct
    11821 accaaaggat gctattatat agatgtaagg aaggaggata ccatcaaata gacagaagaa
    11881 tttctcgata gaacagtgta agcaaacaaa gttgttagaa gtacaggttt cacccagaca
    11941 tgcgtgtaga gtacaaacct ataaatagtg aatgcgtatg gatgtttgga tcacgaagta
    12001 tccgaaacaa gaagtaatgc gatacgtaac aattgaataa cgtaaacgtc tgaaaattga
    12061 ataggaacaa gagatgtttc aaatgttgaa gatgtaacga aaacaaaatt tttgtttaac
    12121 atgaagaaat tcaacaccgt gctttgcatg tatgatggaa agttacaatc atttctgttt
    12181 atttgaatcc ttccgaggta caagaaagcc gagcttatcg agagctcggc tttttctttg
    12241 tcataaaatc tttgtaaagc ttttttgtta ttcaaaacta gcggcttttc ataaccttat
    12301 ttcacgaaca tcgcatctcc aaaactaaag aaacgatagc gctcttcaat cgcatgctgg
    12361 taagcagata aagtcaattc tcttcctgca aaggcactaa ctaacatgac taaagtcgat
    12421 tttggcaaat ggaaattagt tgagaaagct tctaccactt tgaattcata gccaggcgta
    12481 atgaaaatat cagtccatcc gctgtctgct ttgatttctc cattaaattt cgttccaatc
    12541 gtttctaatg ttcgaattga agttgttccg acagccacga ttttcccgcc atttttacgt
    12601 acttggttca atcgctcagc cgcttcttcc gtcaaacggt agaattcact atgcatatgg
    12661 tgttcttcaa ttttatctac gctgacaggt cggaatgtac ctaaccctac atgtagtgtc
    12721 agatagacta attcaacacc ctttgcttcg atctcatcaa gtaattcttt cgtaaaatgc
    12781 aatccagctg ttggcgctgc agcagaacca ttttctttcg catagacagt ttgatagcga
    12841 tctgggtctt ccagacgttc tttgatatat ggaggcaatg gcatttctcc caatgattca
    12901 agaatctcta gaaaaattcc ttcatactca aagtcaatga tccgtccgcc gtgttccaat
    12961 tcttctttca ctactgcttg caatctgcca tcaccaaaag agattcttgt cccaactttg
    13021 gcacgtttcg caggtttgat caatgtctcc cacgtatctc cttgtgtatt cgttagaaga
    13081 aggacttcta aatgcgcacc agtatctggt ttttctccat ataaacgagc aggcagaact
    13141 cgtgtattat tcataactag cgcatcacca ggctgtaact cttcaatgat ttcatggaaa
    13201 tgtttatctt ccatctctcc agttttccga tccaaaacaa gtaaacgaga atgatcgcgg
    13261 tcttttaatg gtgtttgtgc gattaattct tccggcaagt caaaatcaaa atcttctgtt
    13321 gttaacatat cgtcactcac tttctatcat gtgcttcatc attctatcat gtttttcgtt
    13381 ctgttggcaa aatcagcact ttttcacttc tattttttgt tttcctaaat aaaaaaacta
    13441 ccctatttgt attttttcat tgttttaggc atactagtaa tagatagttc ttcattgaaa
    13501 atagaaaaag aggtggcacc atgattgaat ttcaaaatgt gtcaaaaatt tataaaggtg
    13561 gaaaagtcgc tgtagaggac gtcaatcttt catttgaaaa gggtgagttc atttgtttta
    13621 tcggtacgag cggaagcgga aaaacgacga cgatgcggat gatcaaccga atgactgatc
    13681 caacacaagg gaaaattttg attgatggaa aatccatcca agaaattgat ccagtggaat
    13741 tgcgacgtca gatcggctat gttatccaaa gtattggatt gatgcctcac atgacgatcc
    13801 gtgaaaatat cactcttgtc caaaaattgt tgaaagtcag tcaagaagaa cggaataaaa
    13861 cagctgaaaa aatgattgat cttgtggaat tgccccgtga gatgttagat cgctacccac
    13921 atgaattatc tggtggtcag cagcagcgta ttggagtcgt tcgtgccctt gcagcgaatc
    13981 aagatatcat cttgatggac gagccattcg gtgcgcttga tccaatcact cgtgattcct
    14041 tgcaagacct tgtcaaagat ttacaagagc gtttgggaaa aacgatcgta tttgtaaccc
    14101 atgacatgga tgaag
//
LOCUS       DACDLM010000068        13983 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.070, whole genome shotgun sequence.
ACCESSION   DACDLM010000068 DACDLM010000000
VERSION     DACDLM010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13983
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.070"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(3..2060)
                     /locus_tag="IV356_002203"
     CDS             complement(3..2060)
                     /locus_tag="IV356_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HAP9015867.1"
                     /translation="MKLFNPKTVLAIGTFAASLSLAGSVDAASTNVMYRLYNPNNNEH
                     FYTSSKKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWL
                     TKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVKSGSHHYTASWKEVQWLTKDYGWKYEG
                     IGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDSKAT
                     QKQVDSAKNKLDSAYKGLKKKPVPTVNKAELQALYNRVKSTAKGDFTEESWNNFQTAL
                     SNAKKVLDDSKVSQTQVNNAKNSLDAAFKGLQHKPETPKEYTVTINHIDNQTGQVIAT
                     DQAKVTSGSTYTAKAKAFKYSEGAKDNFSYKVIGNDTQSKTITGNTTITFNYNQVHQI
                     NLLCNNNYKNEGRVNILKEQIVNVTHGDSVTLTAPSIQGYVLDDRVEPTNSVTLNNVT
                     ESQNYIFNYTRKFNVTVNHVNADTNAVLSSESKTVYEGDSFATPWKNMTDQNYFLCRN
                     DDPTVTVDKNGQRSINNVDQNKTITFKYKKISLDELRNFMRQKELAWLNDYRQQNGVA
                     PMQFNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENISQTGLYID
                     DLLSDDGAIDAMVGWKNSPAHNANLLYNNQSILGLGHNFVVDSAGRIGVDNVFISANP
                     IFK"
     gene            complement(2174..2386)
                     /locus_tag="IV356_002204"
     CDS             complement(2174..2386)
                     /locus_tag="IV356_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015868.1"
                     /translation="MYADKKKIEWLLFDSGKSVRSISIESGVPLTTVSDLANKRSSID
                     NMRFINAMKLNKLAEEIVDINTSTNK"
     gene            2573..3040
                     /locus_tag="IV356_002205"
     CDS             2573..3040
                     /locus_tag="IV356_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015869.1"
                     /translation="MKKKQLWFVSMFAIFFIILSGCSSNKKSEAKEDNSLLQPGTVWK
                     EEVGGLIHNLKIIDDTTWEYSESVWHPDPVQITVKRQKDYEGLERYKIVDSAGIREFI
                     NKPDSLFIVVPYEKDGVKKIIFLGSSKDEKRTKEKLIHDGSELNKYKLQKTSE"
     gene            3037..3279
                     /locus_tag="IV356_002206"
     CDS             3037..3279
                     /locus_tag="IV356_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015870.1"
                     /translation="MIASLFIYPEGGITVAKVKTPFEKAASKILERRGVSEIQWKKEV
                     LEKAQFDLLRGKDKDLEEYIYQREREKLVFDEIIKH"
     gene            3297..3599
                     /locus_tag="IV356_002207"
     CDS             3297..3599
                     /locus_tag="IV356_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015871.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAVAA
                     VASIALGGIFFFFGRRGAENGKTHVGYVLLGVGVILAAASIVVSMFSMFGQTPQGL"
     gene            3671..5725
                     /locus_tag="IV356_002208"
     CDS             3671..5725
                     /locus_tag="IV356_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015872.1"
                     /translation="MFFTISGNAKLDKELIRKATKKVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDKEGKIEKAGTEYVFGPLDYQISEGFYPTLIDLIR
                     LDVFKDTDETMSVEESYRNEKLLQVLEEELESDQRKVNQVSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETDEVEVDPVEA
                     NEESTWTEGDFQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKVKEELNKEEQRVIEEEVQKVKERYEKKRDNAYSLCVE
                     KINNFTKTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMEKHEQIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLEIRKREQD
                     LAEQKMAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPVAAVQTPVNNQ
                     ANLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQE
                     QARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKAKEGSSDSTVQSNTSESSESNE
                     VK"
     gene            5725..8337
                     /locus_tag="IV356_002209"
     CDS             5725..8337
                     /locus_tag="IV356_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HAP9015873.1"
                     /translation="MRVRETTKRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     KKIFYSGLVYLPLEYLVTRVPEVFNRLEIVKGSLQGINLFQLQEMPQVFHFDSAGFWN
                     PFTPTTSLGTRLAISTVCVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPENEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSIGFPKYLDLKLHESLLNQRIVVEFYHKGK
                     KFHEERVKVGYRGFCEINFDCHLEQGDHVCLKYNHQGKQYVAWYEFSQKVLKDEEGKI
                     VYRKKRGETHLPELEKEAVLTLDEKKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSFENETAKKLLIQFYEEQATDRLQEYVEKLIKNEEISEMI
                     RKRLLLEAEKAVKE"
     gene            8334..10712
                     /locus_tag="IV356_002210"
     CDS             8334..10712
                     /locus_tag="IV356_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015874.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDADPKTVTKVLQDYGNYLQYQDV
                     FSWICNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKNFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PDQAKKMSESSDISTVQKDRLKALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYRRY
                     ISSPGIILAGESSLSVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSAIE
                     DISQSFLLLAFTILELRIYTLMLSGIGDLHAVGKINGFLYVVALIVLTIALFKGSQSV
                     TKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGFGH
                     RKDITHDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGTVE
                     DLTEKAKDTLEEKLDGTRAKEFAEAVKNPSEALEKQKEKASAVKEGLKDAYGEGQVNA
                     AVKANTTSEKENQEGAAIPSAKDHQDELHSNENSIGEKDSEEGQHGQLPKTDPEQYRY
                     KSNINSENEKRISDLPKRNQEVQTDEDSIDLPNDNGIEVGTEKSTKIGLPKTQNLPMK
                     DSRLNQFKENDQSFVHQSPAGTVQMKSSRLPENGNLTTVSYNLAESGETENASVQNIV
                     TKEAAPKPINKVHNGYRPANVAFTAPTKINVTRETKNRNNELKEQLLKDIKP"
     gene            10773..11315
                     /locus_tag="IV356_002211"
     CDS             10773..11315
                     /locus_tag="IV356_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015875.1"
                     /translation="MEDILIATFITALGAFLTIFVVTIKGFKDTDSLQKDHQSILDGQ
                     KTHTESIIVHLSEGFTYLKDAMPTFTVKLTEIFHSVEQISSELKEQRQQKDRQLGSLN
                     FRQETIQESLENVNRLNDEMQRVHLENEELRAQNYDLIQKKRNLEQKIVELKEENRQL
                     NYQLRRGKNRSRDLGNELEL"
     gene            11393..11725
                     /locus_tag="IV356_002212"
     CDS             11393..11725
                     /locus_tag="IV356_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015876.1"
                     /translation="MDKYIHMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKIVNNLV
                     HLPLFFALLNYGLWLAIALVIVWRPYNNPGQRQIFAIIESIFFTDKNHYHALDPNRNY
                     HGTYKEDE"
     gene            11726..12319
                     /locus_tag="IV356_002213"
     CDS             11726..12319
                     /locus_tag="IV356_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015877.1"
                     /translation="MRVKGQNSVDKKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLRKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            12341..>13983
                     /locus_tag="IV356_002214"
     CDS             12341..>13983
                     /locus_tag="IV356_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAP9015878.1"
                     /translation="MLDVIKTAFSTQSNQKVIDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLAFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDEC"
BASE COUNT         4940 a         2213 c         2780 g         4050 t
ORIGIN      
        1 ttttatttga agattggatt cgcactaata aatacattat ctacgccaat tctaccagca
       61 gagtcaacta caaaattatg acctaatccg agaatacttt ggttattata aagtaaattt
      121 gcattatggg cagggctatt tttccatcct accatggcat cgatagcacc atcgtctgat
      181 aaaaggtcat caatatacag cccagtttga cttatgtttt ctcccttagc accgtagcag
      241 cctaagcttt ccaataaatc ttggaaagta ccaccaccag ggcgatagtg actgaagctg
      301 acttgtaatt ctttagctcg aatatctgca gcctgttgaa caatatcatt gaattgcatt
      361 ggggcaacac cattttgttg gcgataatca tttaaccaag caagttcttt ttgacgcata
      421 aagttacgta attcgtctaa tgaaatcttt ttatatttga atgtgattgt tttattttga
      481 tcgacgttat taatggatcg ttggccgttt ttatccacgg taacggtagg atcgtcattt
      541 ctgcacaaga aataattttg atcagtcatg tttttccaag gagtagcaaa gctatcccct
      601 tcgtatactg tttttgattc actagagaga acagcgttgg tatcagcatt tacatgatta
      661 acagtcacat taaatttacg agtgtagttg aaaatataat tttgactttc agtcacattg
      721 tttaaggtta ctgaatttgt tggttctacc cgatcgtcta aaacatatcc ttgaatagaa
      781 ggagcagtta aagtgacact gtcaccgtga gtgacattga ctatctgttc tttcaaaata
      841 ttaactcgtc cttcgttttt gtagttgtta ttgcacaaca aattgatttg atgcacttga
      901 ttataattga atgtgattgt tgtattacct gtgattgttt tgctttgagt atcattacca
      961 atcactttgt agctaaaatt atctttagcg ccttcgctat atttaaatgc ttttgcctta
     1021 gcagtgtaag tagaaccaga agttactttt gcttgatctg tagcaatcac ttgacctgtt
     1081 tgattgtcaa tatggttaat agtaaccgta tattcttttg gtgtttcagg tttgtgttgc
     1141 aaccctttaa atgcagcatc aagactattt ttagcattgt ttacttgtgt ttgagaaacc
     1201 ttagaatcgt ctagtacttt tttagcattg gataaagcag tctgaaaatt attccaagat
     1261 tcttctgtaa aatctccttt agcagttgat tttactcggt tgtataaagc ttgtaattca
     1321 gctttattca cagtaggaac tggttttttc tttaatcctt tgtaagcaga atctaattta
     1381 tttttggcac tatccacttg cttttgagtc gcttttgagt catttaacac tttcttagca
     1441 ttgtttaaag cggtttggaa tgcgttccag gtattgtcgg tatagtcacc ttttttcgtt
     1501 cccttaacgc tcgtataaag agcttctaga gccgatttat tcactttggg tttagaggtg
     1561 tcagcgccat accaaccgat accttcgtat ttccagccat agtctttggt taaccattgt
     1621 acttctttcc aacttgcagt gtagtgatgt gagccagatt ttacaccagg aaggaaaagg
     1681 cggtagatcg gtttattatt tttttcggca gaacgccagg caggcccttc ataagtccag
     1741 ccgtaatttt tagtcaacca tttcacttca tcccaactag ctgtgtaatg gtgatcacga
     1801 agacctttat tgtacaaacg atagacaaga tggccaccgc tagtcggtgc ttcccaggcg
     1861 gggccttcat aatttcccca ttttatcttt actagatggt cacgttcttt tttgctagag
     1921 gtgtaaaaat gttcattatt atttggattg taaaggcgat acatgacgtt agttgaagca
     1981 gcgtcaacag atccagcaag actaagtgag gcagcaaatg ttccaatagc taaaacagtt
     2041 tttggattaa ataatttcat tttttcaact cctaaattta attaaaaatg tttacatgat
     2101 tattatatat cggctaaccg atatagtcaa taaaaaataa gaaaagcctt atataatttt
     2161 ggcttttctt attttatttg ttagttgaag tattaatatc aacgatttct tcagccaatt
     2221 tatttaattt catagcattt atgaatctca tgttgtctat actagagcgt ttgttggcaa
     2281 ggtcacttac tgtagttaag ggtacgccag attctatgga tatagaacga actgatttac
     2341 cactatcaaa cagcaaccat tcgattttct ttttatcagc gtacatttca atgctccttc
     2401 ttgttttttc tttattatag ctcttttttg taatgaatca caatatcaag agaaaaattt
     2461 tctatagaaa ggtggatttt tatgagtatt cgttctccgt gtatccaaat gaggtttgtt
     2521 gctactttcg ttatttgata tactaaaaat aaacaacgaa agaaggaata aaatgaagaa
     2581 aaagcaacta tggtttgtct ctatgtttgc aatatttttt attattttaa gtggatgttc
     2641 aagtaataag aaatcggaag ctaaagaaga taatagttta ttgcaaccag gaactgtttg
     2701 gaaagaagaa gtaggtggtc ttattcataa tttaaaaatt atagatgata ctacctggga
     2761 atattctgaa agtgtatggc atccagatcc tgtacaaata acagttaaga ggcaaaaaga
     2821 ctatgaaggt ttagaaagat acaaaatagt agattctgca ggcattaggg aatttataaa
     2881 caaacctgat tcattattta ttgttgttcc ctatgagaag gatggcgtaa aaaaaataat
     2941 ttttcttgga tctagcaagg atgagaagcg aacgaaagag aaattaattc atgatggatc
     3001 agagttaaat aaatacaaat tacaaaagac tagtgagtga ttgctagtct ttttatttat
     3061 cctgaaggag gaatcacagt ggcaaaagtt aaaacaccat tcgaaaaagc cgcgtctaaa
     3121 atcttagaac gccgtggtgt ttctgaaata cagtggaaaa aagaagttct tgaaaaagca
     3181 caatttgacc tattacgagg aaaagataag gacttagaag aatatatcta tcaacgtgaa
     3241 cgtgaaaaac ttgtattcga tgaaattatt aaacattaaa aggagcgaat aatcttatgt
     3301 ttgaatcaat tacaatgaat tttttaactc aaccgaaagt agtagctgca gttgatattt
     3361 ttagagcatt acaaactgcc gcaactagtt tgaaaaataa tctgatgatt tttgctgctg
     3421 ttgcggcagt ggcttccatt gctcttggag gtattttctt cttctttggg cgaagaggag
     3481 ctgaaaacgg gaagacacac gtaggttatg tattgttggg ggtaggagtt attttagctg
     3541 ccgcttctat tgtagtttca atgttctcaa tgtttggaca aaccccacaa ggactataaa
     3601 aaaaacaagt aggaggagta aaaagtacgt ggctactttt tactcctttt tttatgaaag
     3661 gagaatattc atgtttttta cgatttcagg aaatgcaaaa ttggataaag agttaataag
     3721 aaaagcaacg aagaaagtgg gaaagcgtac ttccttttta ccgaaaacaa ttaaatattc
     3781 tgtcattgaa acggaagaac agctacatgt gttaggacaa gtgttagaac aagagaatca
     3841 atcttctgtt aaattgactc tcacgttaca tgataaagaa ggaaaaatag aaaaggctgg
     3901 cacagaatac gtttttggcc cactggatta tcaaatttca gaaggttttt atcctacatt
     3961 gatagattta atccgccttg atgtgtttaa agatacggat gaaactatga gtgtggaaga
     4021 gtcttatcga aacgaaaaac ttttacaagt tttagaagaa gagttagaga gcgaccaaag
     4081 aaaagtgaat caagtgagtg aagtcgaagt aaatgaagaa gtaccatggg aacgaccaat
     4141 ctttccaaag aaggagtcaa aagaaaaaga gacagtctat gttgacgaac aagctgatat
     4201 tccgactcag aaatcgatat ttgaggaaga gaacgatgtg atgggtcaat tggaggtaga
     4261 tccctttgaa gaaacaatgg aggatgaaga gacggacgaa gtagaagttg atccagttga
     4321 agctaatgaa gagtcaacat ggactgaagg ggattttcag gaatatattg aaccacttat
     4381 cagtgaagaa gtagaaaaaa acgaaacaga gatacaaaag gcaactgtat ttgattatat
     4441 tttggatcaa tatccgccag agcatgaatg gatgaaagaa aaaaacaaat tatttttaaa
     4501 tgagctttat tcgaaatatc aattacccca aacctatcaa gcatttttag agagtaaaga
     4561 agaattaatc tcacagggta aaggcacact tttagaacag ttagagtctg tccaatcaac
     4621 aaattggcat gagcttgcac aagaagattt attagccacc tttgaagaac gtcaacaaga
     4681 aacagatcaa gaaattaatg agtatgcgac ggaacagtcg tctaattggg agaaagtaaa
     4741 agaggaacta aataaagaag aacagcgagt gattgaagaa gaagtacaaa aagtcaaaga
     4801 gcggtacgaa aagaaacgcg acaatgctta ttccttgtgt gtagaaaaga tcaacaattt
     4861 tactaagacg aatcaagaag cgttatcgaa agaaaaagaa aacttgttaa aagaacgtat
     4921 taaagaacga aaagaagagt tctaccgcgg tttacgtaca gataagctaa agattagcaa
     4981 agaattaaat gaacaactga ataagctata tcaaacaacg actgaagttc ttatggaaaa
     5041 acacgaacag atccagcaag aattacaagt acaaattcca aaatggaaaa aagagtatga
     5101 aattcaacaa caagaattga aagaacaaga agaaaaacaa cggcaaaaag aaaaagagcg
     5161 tgaacaatta gaaataagaa aacgggaaca ggatcttgcg gaacaaaaaa tggcgataga
     5221 aaaacaacgg ttagagcaag aaaaggaaaa agaagcagct gctcgtaagg aacgtcaaga
     5281 acaaatggat acattgcgtc aagcacagtt gaattatcta gcacaacctc aaccagtagc
     5341 tgctgttcaa acgccagtga acaaccaagc aaatttaact ccttcacccc agcgttcctt
     5401 taacggatgg atggtgggat gtattgcaag tttaagcttg cttctaggtg gaggaacagt
     5461 atttgctttt aatcatatca atcaatcttc acaggctgat tctgtagcca caacggcgtc
     5521 aatcaaggaa gaagcccagg aacaagcaag aaaagagtat gaacaacaat tagaagaatt
     5581 attgaatcgt accaatcagt caacaacaga gtcaagcatg gaaaatagca aagagagtga
     5641 ttctagtaag gctaaagaag gatcaagcga ttcaactgta caatcaaaca cttccgaaag
     5701 ttcagaatca aatgaggtga aataatgcgt gttagagaaa caacgaagcg aaaagacaaa
     5761 cgattcaatt tagaaaagaa taggtatctt tctcatttct atcgctatac tccctcagga
     5821 gaagagctac cagaaaaaca tgacaaacgc atttcgaaaa agatttttta tagtggactt
     5881 gtatacctcc ctttagagta tttagtaaca agagtaccag aagttttcaa ccgattggaa
     5941 attgttaagg gaagcttaca aggaataaat ctgtttcaat tacaggaaat gccacaggtc
     6001 tttcattttg attcagctgg tttttggaat ccatttactc ctacaactag tttgggtaca
     6061 cgtttagcaa tttcgacagt ttgtgtggtt ccagctgtac ttatgggatt gaaaatggac
     6121 atgtggtttc gtcctctagc agatggacaa aaaggggata atcgattaat gaccttaaaa
     6181 gaaatccaac agatttatcc gcaaatacct gaaacaaaaa ctacttttcc aggttatgga
     6241 ggtattccaa tcacacatta caaaaaatat tggtacattc aaacagatac tgttaatacg
     6301 tgtattgttg gtacctctcg atcagggaaa ggtcagattg aagtgttagc caccattgac
     6361 aatttatctc gtgcagaaaa acaaagttca atggtcgtta atgatccaaa aacagaatta
     6421 tatgttggta gtaaagatga actagaagct agagggtatg atgtatatgc ctttaatatc
     6481 accgatccac tgcaatcaat gagtgataat ccattggcac tcattgtgaa atactggaag
     6541 cgaggagaca tagacaccgc aacacagtta accaatactt ttacgaatac gatttattat
     6601 gatgcaaatg cttcagacaa taaatacttt aacgaaaatg cgcagaaagc tgtcaatgcg
     6661 cttatttttg cgttattgga acaagcggat caaacagggg attactccaa attaacacca
     6721 aataatctcg ttgaactact ttcagaaatt ggcggtttta attattatcc agatcctgag
     6781 aatgaattca agcagctcaa tgccttagat gagttcatga atcagttacc ccctggaaat
     6841 atagcaaaaa aacaatatgg ggcaacaaaa attggatctg ataaagcgaa agggaatatc
     6901 ttgtctacgg caattacagg attgaatcca tttaccctaa cgaaaattgc gaagatgact
     6961 tctcaatcga ccattgatta caagtccatt ggttttccga agtatttgga tctcaaatta
     7021 catgaaagcc tattaaatca acgcattgtc gtggaatttt atcataaggg aaagaaattt
     7081 cacgaggaac gagtcaaagt tggctatcgt ggtttttgtg aaatcaactt tgattgtcat
     7141 ttagagcagg gagatcatgt ttgcttaaaa tacaatcatc aaggaaaaca atatgttgct
     7201 tggtatgagt tttctcaaaa agtattgaaa gacgaagagg gaaaaatcgt ttatcgaaaa
     7261 aaacgaggag aaactcattt gccagaacta gaaaaagaag ccgttctaac attagatgag
     7321 aagaaaagta acctattagt agagtctatt cggatgcact ataccgataa accaatggct
     7381 atttttatgt taacgcctga ttatgatcca tctaaccata tcattgttag catctttctt
     7441 agtcagttgt ataaagaatt atctacgcaa tgtgttaaga ctaaaggaga taaatgtcac
     7501 cgtaggattc attttatttt agatgaattt ggaaatatgc caccgatgga caacatggaa
     7561 ggaatcatga cggttacggc aggtcgtaat atgttatggg atctgtttat tcaatcttat
     7621 cagcaacttt atgcgaagta tggagaacaa aacgcagcga ttatcaaaga aaattgtcag
     7681 acacatattt atattatgtc gacagatgat aataccatcg aagaattttc taaaaaagtg
     7741 gggaataaga cggttgaaca agagaacagt accatcaatt cattaggtat gaatactcat
     7801 atcaatcgca atgttgattc agatcgtatc ttaactcctg aaagaatttc tactttttta
     7861 gaaggtgaaa cgattgtact cgctccttta aaacgacaag atttgaaagg tcataaaata
     7921 cggccgtatc ctatttttaa tcatggggaa acgaatcttc cttatgctta tcaatatatt
     7981 gaagatttca atccatcgtg ggatatcaat gatatagaca tacattgtac acatgcggac
     8041 ttggatctta aggctttaca aattgattat gattatttcc taccagatga atatgctaga
     8101 aatctctatc atggactgca tgatcaatta gaagaaaaaa acgaagaaaa tatgttttat
     8161 aaaatcgttc aatcttttga gaatgagacg gctaaaaaat tgttaattca attttacgaa
     8221 gaacaagcaa cggatcgtct tcaagaatat gttgaaaagt tgatcaaaaa tgaagaaatt
     8281 tctgaaatga ttaggaaacg gctgttattg gaagctgaaa aggcggtgaa agaatgatca
     8341 ttggaggaat tttctctggc atagccgact ggtggtcagg tttattcgga gaaggggatg
     8401 cagatcccaa aaccgtaacg aaagtcttac aagattatgg taattatctg cagtatcaag
     8461 atgtattcag ttggatttgt aatacttttt tatggggatt gatcaaaggg ttatataatc
     8521 tcaatacttt attagaaaaa acaatttatc aaagctttga tttaaaagac ttattgaacg
     8581 ccgctggtgt taatgaacta tttcaaagtt tgattagtaa ggtattggct cttttttgtg
     8641 tcgtcacatt aatttattta ggcttgaaat tttttatgag taaacaccca ccgaaagtca
     8701 aaaatatctt ggttaattta tttatggcca tgatcttgat ttttggtggt agttctttaa
     8761 tcgatgaagg gttaaatatc agtaaaaact tttatggaga cgtcactgca gcaaataaag
     8821 cagataaaac gggttcacct gcttttcaaa ttattcaaaa taatgtgatt gatgtcagta
     8881 cattactagc gactgacccg aataaagtag aatccttacc aacagataaa agaaatgctt
     8941 taacagcgaa aaatttcaaa acagcgaata tcaatgggat tattacacct gatcaagcta
     9001 agaaaatgtc tgaatcaagt gatattagta cagtacaaaa agatcggtta aaggcattac
     9061 agtatcgact agagttagac gataatggga aagaaatccc tgttcaaatt agtgatgaag
     9121 gtttagcaaa atatgtgtat acgtcaggct atcgtcgata cattagtagt ccagggatta
     9181 ttttggctgg ggaatcttct ttgtcggtag cctatttatt tattttgttt acaatcgtta
     9241 cttgcattat tgagctagta tttaaaaaat tctatttagt aattgccgcg tcaacggact
     9301 ttgagacagg acaacggatg aaaagtgcga tagaagatat ttctcaatcc ttcttgttat
     9361 tggcgtttac gattttagaa ttacgaatct atacattaat gctttcaggt atcggtgatt
     9421 tgcatgcggt aggaaagatc aatggattct tgtatgttgt tgctttaatt gtgctaacta
     9481 ttgcgctatt caaaggctct caatcggtta cgaagatttt cggtgttgat acgagtctga
     9541 aaaacggcag caattctctt cttagcatgt ttgccttagg aaatattgcg aaaaatgtgg
     9601 gtagcggagc taaaaacctt gcaagtgctg gtaagagtgg tttaagccat ttaaatgata
     9661 ttcgtaagaa tggatttggc catcgaaaag atattaccca tgataacggg gaagaacaat
     9721 cagacgataa agctacaact gtacctaata gtaagaagac agtttccgaa atgttcggga
     9781 aagcgaaaaa tggtgtttct aaagccgcag aaggtcttgg ttacgtcaat gaacgtgggt
     9841 taaaaggaac agttgaagat cttacagaaa aagccaaaga caccttagaa gagaaattag
     9901 acggcacgag agctaaagaa tttgctgaag ctgtgaagaa tccatccgaa gcactagaaa
     9961 aacaaaaaga aaaagcttca gcagtcaaag aaggactaaa agatgcgtat ggtgaaggac
    10021 aagtcaatgc agcagtgaag gcaaatacaa caagtgaaaa agaaaatcaa gaaggtgcag
    10081 cgattccttc agccaaagat caccaagatg agttacattc taacgaaaat tcgatcggag
    10141 aaaaagattc agaagaagga caacatggtc agttaccaaa aaccgatcca gaacaatatc
    10201 gttataaatc taacattaat tctgaaaacg aaaaacgcat ttcagattta ccaaaacgaa
    10261 atcaagaagt acaaacggat gaggattcca tcgatctgcc aaatgataat ggcatcgaag
    10321 ttggaactga aaaatcaacg aaaattggtt tgcctaagac acaaaattta ccaatgaaag
    10381 atagtcgttt gaatcaattc aaagagaatg atcaaagctt tgttcatcaa tcacctgcag
    10441 gtactgttca aatgaaatca agtcgtttgc ctgaaaatgg aaatctgaca actgtttctt
    10501 acaatttagc tgaaagtggt gaaacagaga atgcgtccgt tcaaaatatt gtgacaaaag
    10561 aagctgcacc taagccaatc aataaagttc ataatggata cagaccagca aacgtagcat
    10621 ttactgcacc gacaaaaata aatgtgacaa gagaaactaa aaacaggaac aatgaattga
    10681 aagaacaact attgaaggat atcaaaccat aaaaggccta tttaagggcc tttttcttta
    10741 taaaacaagt ttaaaatgga aaggagaaaa ttgtggagga tattttaata gctacgttta
    10801 taactgcact gggagcattt ttaacgatat ttgtggtgac tattaaagga tttaaagata
    10861 cggatagttt acaaaaagat catcagtcta ttttagatgg tcaaaaaaca cataccgaaa
    10921 gcattattgt acacctttca gaaggattca cttatttgaa agatgctatg cccacattca
    10981 cagtaaaatt aacggaaata tttcattctg ttgagcaaat atcgtcagaa ttgaaagagc
    11041 aaagacaaca aaaagatcgt caacttggct cacttaattt taggcaagaa acgatacaag
    11101 aatcattgga gaatgtaaat cgattaaacg atgaaatgca acgagttcat ttggaaaatg
    11161 aagaattacg cgcacaaaat tatgatttaa ttcaaaagaa aagaaatctg gaacaaaaaa
    11221 ttgttgaatt aaaagaagaa aatcgtcaat tgaattatca attacgacga ggaaaaaatc
    11281 gttctcgtga tttaggaaat gaattagagt tgtaatattt agaaaaacgc tgtgagaaat
    11341 cacagtgttt tttatttcta aaaatacaaa atataagggg tatggttata ttatggataa
    11401 atacattcat atgaaaaatc ctccaagatt tagtggggaa tggaagtttt tcgccttttt
    11461 ctttttagat ctattaacgc ttggtggctg ctttttttgg gcgaaaatag tcaataatct
    11521 tgtccactta ccactctttt ttgcactctt gaattatgga ttatggcttg cgatagcgtt
    11581 agtgattgtt tggcgaccct ataataaccc tggtcaacgc caaatttttg cgattatcga
    11641 atctattttc tttacggata agaaccacta tcatgcgtta gatcctaacc gaaattatca
    11701 tggtacgtat aaggaggatg aataaatgcg agtcaaagga caaaattcag ttgataagaa
    11761 atccattttg cagtttggaa aaccagaaga gcgctctatc ttggacttat ttccatataa
    11821 atcctgtaca gaagagggag tcttaattac tagagaagat cattttcagc gttattatcg
    11881 tgtcgtttcc actgacgtgg agggattaaa tgaacaagag aaactagaac gaatgaatca
    11941 gttgaccacc gtcatgcgta cgtatgtgcc aacaattaag ttagttagtt tgaccacaga
    12001 gacggatcta acggaacaaa tcgtgcaaaa gcggcagtta ttagataaaa atcgtatgga
    12061 acagtcacta ggaagaaatc tacagcgatt aagaaaatat gaaaagaaat tagtagagga
    12121 gatccaggaa ttaaaacggg cagaacaaga acgtcctgac ttaagcttct ttttcgttat
    12181 tgaaggaaag acaatcaagg atttacaaac tagaaatcgt cagttaatgc gatctagtgg
    12241 cattttaggg ttaaaaccac tctacaaaaa agaattgatt aagattcttt atcgaatgaa
    12301 caacatgaat gacgaataaa aaagatggag gaaatgattc atgctagatg tgataaaaac
    12361 agctttttca acgcaaagta atcaaaaggt gattgatcca ttaaaacaac ttggtaatcg
    12421 tgaaatagag attttaaaat caaaaggtta tgatttagat ttcttaaaac aagtgatgcc
    12481 acaaggtggg ttgaattttg atgaagaata tgtgacctat ggaaatggtt attcacgatg
    12541 tgtgacagtt tatcattaca caaaaaatcc tactcttttt tggttggcca atctcatgaa
    12601 caatcctcat acagtggcca cactagatgt tagcacagat gaaaagcaaa aagtgattga
    12661 tcaaatcaac cgcgcattag atgaattaaa tgatcgatca gataatgaac gaaaagcgac
    12721 tgaccgaaat aaaagtgcgg aagaatacct ggaactagcg gaatatgccc gaaaattgac
    12781 ttctaatggg gaaatttcta aacaagtcaa agtgagagta catgtttacg gaaatacgat
    12841 ccaagaagtg gatgaacggg cgcaggaact gatcgaaaat ctaaaaggga tggattatcg
    12901 tgcggtgact tatctgcata aaaccaaacg agattggcaa tcgatgttta ccatgttcga
    12961 tgaacaagct gaatggtttg gaaatatcaa agggcaatca cttccatcgt taaacattgg
    13021 cggaggattc ccgttccacc accaaacgct aaaagatcca ggaggcacac aatatgggga
    13081 aaccatgaca ggcggcccat ttgtctggaa tgccacgtat aaaaatagtg tacgtttatc
    13141 taccaatacc ttgcttctag gaatgatggg agctggtaaa tcgaccgttc ttaaaatgat
    13201 cgcggaagcc catttagctg caggagactt tatttggggc tttgaaaagg gaaaagactt
    13261 tattcctttc ttaaaggaat ataacggtat tatggtgcgt ttagacggat ctgacggaat
    13321 gatcaatcct ttagagatat ttgccacacg gacgtatgat gaagcatcca gtttatatga
    13381 cgatggatca gtcaaagatt tgaagatcaa tgaagcagcg tcctatcaaa cacacttaga
    13441 caaagtggtc tatcaggtac agttagtgag tcctcagcta aaaggaacga tgaaagcaga
    13501 atttaagacc tacttaaatc gtttttatga agagtatgga acagtaccac gcggctttac
    13561 ttcctcaaat tcgcgttcaa atactgatac gcaagtcaca gggaaagatc cagaagctta
    13621 tccgacgttc aaagaatttt tagccttttt aggacaactg gaactaccag gggcttccca
    13681 agagaaaaag aatcggaaag aagaaatgga gtctatcgtg gaatccttat gtgagactta
    13741 tggcatgatt tttgatggtc atagtacgat tcgacacctt gaccaacaac agttggtctt
    13801 ttttgacatt gactctatta caggcctaga tcgaggggta caacaatgtc agatgtacat
    13861 ggccatgacg ttgatttgga atcaggcatt gattcaagga cgaagacaac gacgcttaat
    13921 taaagaaaaa caaatggaag aacaagactt caaacgcttc ttggcgatga ttgatgagtg
    13981 cca
//
LOCUS       DACDLM010000069        13818 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.071, whole genome shotgun sequence.
ACCESSION   DACDLM010000069 DACDLM010000000
VERSION     DACDLM010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13818
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.071"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(163..2160)
                     /gene="tkt"
                     /locus_tag="IV356_002215"
     CDS             complement(163..2160)
                     /gene="tkt"
                     /locus_tag="IV356_002215"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HAP9015879.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2262..2513)
                     /locus_tag="IV356_002216"
     CDS             complement(2262..2513)
                     /locus_tag="IV356_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HAP9015880.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2660..3283
                     /gene="lexA"
                     /locus_tag="IV356_002217"
     CDS             2660..3283
                     /gene="lexA"
                     /locus_tag="IV356_002217"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HAP9015881.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3463..3681
                     /locus_tag="IV356_002218"
     CDS             3463..3681
                     /locus_tag="IV356_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015882.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3970..4482)
                     /locus_tag="IV356_002219"
     CDS             complement(3970..4482)
                     /locus_tag="IV356_002219"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HAP9015883.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4496..6793)
                     /gene="recJ"
                     /locus_tag="IV356_002220"
     CDS             complement(4496..6793)
                     /gene="recJ"
                     /locus_tag="IV356_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HAP9015884.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6935..7369)
                     /locus_tag="IV356_002221"
     CDS             complement(6935..7369)
                     /locus_tag="IV356_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HAP9015885.1"
                     /translation="MKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPLILV
                     IIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQREFRN
                     ERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7379..8167)
                     /locus_tag="IV356_002222"
     CDS             complement(7379..8167)
                     /locus_tag="IV356_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP9015886.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8164..9105)
                     /locus_tag="IV356_002223"
     CDS             complement(8164..9105)
                     /locus_tag="IV356_002223"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HAP9015887.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9282..9869)
                     /locus_tag="IV356_002224"
     CDS             complement(9282..9869)
                     /locus_tag="IV356_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HAP9015888.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10090..11403)
                     /gene="obgE"
                     /locus_tag="IV356_002225"
     CDS             complement(10090..11403)
                     /gene="obgE"
                     /locus_tag="IV356_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HAP9015889.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11700..12710
                     /gene="gap"
                     /locus_tag="IV356_002226"
     CDS             11700..12710
                     /gene="gap"
                     /locus_tag="IV356_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAP9015890.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12795..13730)
                     /locus_tag="IV356_002227"
     CDS             complement(12795..13730)
                     /locus_tag="IV356_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP9015891.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         3810 a         3096 c         2436 g         4476 t
ORIGIN      
        1 tctcaagaaa cacaaactaa tccgaagaat tctttgtttt gtcatttaaa tgtaacatag
       61 ccgaaaacga aaagtaatat tgatttattc ttctaacaca taaagaacag ctgtctccaa
      121 cttgcagaca gctgttctta tcagtcaaac aattgcttgg atctatgata gttgattgta
      181 cgtattcacg acattttcta ctgtaaatcc aaattcttct aaaattttag tgccaggggc
      241 agatgcaccg aaatgatcga ttgtaatcgt tgcgccctct gttcctacgt agcgttccca
      301 tccaaatgat gcagcagctt cgatagccac acgtttcttc actgatttag gaagtacact
      361 ttctttatat tcagaagatt gtttttcaaa gaggtcaaag cttggcatag aaacaacaga
      421 aacatctttg cctttttcag ccaattcttt ttgagctttc acagccaaat caacttcaga
      481 acctgttgca atcaaaatac cttctggtgt ttctccttgt gatggagaaa gaacatacgc
      541 gccttttttc accatttcat ctgctacttc ttttgtagaa ggcaatactg gaaggttttg
      601 acgactcaat acaaggatag taggcgcatc tgttgtctcc atcgctactt tccaagcagc
      661 acgtgtttca tttccgtctg ccggacgaat cacttgaaca ccaggcatgc agcgaacaga
      721 tgctagttgt tcaatcggtt cgtgcgttgg tccgtcttct ccgacagcaa ccgagtcatg
      781 tgttaagacg taaacaacag gagtatgttg gattgctgct aaacgaactg ctggtcttag
      841 ataatcgaca aagacaaaga atgttccacc gtagatacga gttccgccat gaagttggat
      901 accattcata gccgaagcca ttgcaaattc gcggacaccg aaccagatgt tgcgtccttc
      961 ataatgttca ggagtgaaat ctttatctgc agccaccatt gtattattgg aacctgacaa
     1021 gtccgctgaa ccaccccaga agcttggtat agctttcgat aattcttgga tgacttcttt
     1081 acttgaaaca cggcttgctt gactgcttcc aacttcataa gttggcaatt ctgcatccca
     1141 gttttctggt agtttgccat caaaagcatc ttcaaattgt tgtgctaatt caggataagc
     1201 ttttttataa ttggcaaaca tttcattcca tgcatcttca gctttttgtc cttcttctat
     1261 catcgtttga tggaagcggg cagctacttc ttctggaaca gtgaaatctg gatactccca
     1321 accataaact tctttagcca tcttgatgcc atcttcacca agaggagcac catgaacagc
     1381 agatgttcct tctttaggag caccatagcc gatgactgtt tttacttcga tcaatgttgg
     1441 tttgtctgtt tcagcttttg cttcttcaat cgctttagag attgcttcta ggtcatttcc
     1501 gtctttcact aagatatgtt gccagccata tgcttcatag cgagcaccaa cgttttctgt
     1561 gaaagctttt gaagttggac cgtctagtga aatatcgttt gaatcgtata aaacgatcaa
     1621 tttccctagt ttcatatgac ctgccatcga acttgcttct tgagataccc cttccatcaa
     1681 gtctccgtca ccgcatattg catacgtata gtgatccatc acattaaagt tttctttgtt
     1741 atacgttgct gcaaggtgcg cttctgccat tgccataccg acagccattg caatcccttg
     1801 tcctaatggc cctgtagtgg cttctacacc atctgtatga tgtacttcag gatgtcctgg
     1861 tgttttagaa tcccattgac ggaattgttt caaatcatcg attgtcactt gatagccagc
     1921 taaatgaagc aagctataca acattgctga cccatgtcct gccgaaagaa cgaaacggtc
     1981 gcggtcagcc cagttttttg atgtcgttgg atttactttc aggtgttttg tccataacgc
     2041 atatgccata ggtgctgcgc ccatcggcaa tccaggatgt cctgagtttg ctttttggac
     2101 tgcttcaata cttaatgtac gaattgtgtt aacgccaagt tggtcaattt tgtcaaacaa
     2161 aataacccct cctattaatt taggtttttt ttacctttat ttcttacact ttcattctat
     2221 aagatgtcac acgaaaaagc aatctttttc agtatttttt actaaaagtt gtcatttcgg
     2281 ttgtgtaagc cttttttctt ttggatttct tttaattttt ccggggtcac gtcattgccc
     2341 tcaggatcga cgactttcat tccttcgata tgatgacgca taccggaacg aaaagcttcc
     2401 aaatactctt tgcgcaagtt gatttgttct tgttcttcgg cttttgagag accattttcc
     2461 ttctttttac gtgcaagttc attgatccgc tctatttttt caggtgacag catgctcagc
     2521 cctcctttta ctctccttca tattatataa aaactgaaaa aaaaacaact agataaacta
     2581 aataaaatac gaacattcgt ttgatttagc gctttttata tggtactatt tatttatcaa
     2641 gtgaaagaag gtgtaccttg tggcccgaca aactgaatca agacaaatcg aagtcttacg
     2701 atatatccat gaacaagtaa cccaaaaagg atacccgccg actgtccgtg aaatcgggga
     2761 agctgttcag ctttcttcta cttctactgt tcacggtcat cttgcacggc ttgaaaaaaa
     2821 agggtttatc caaagagatc cgacgaaacc tcgtgcaatc gagttgacaa aacaaggttt
     2881 agaaaagatt gggattcgtc caacaactat tccagtactt ggcgtcgtaa cagctggaga
     2941 acccatttta gcagtagagg atgcttcaga cttctttcca atccctccta atctttcttc
     3001 cgaagaaggc agtctcttta tgctgacaat tcgtggagat agtatgatca atgctgggat
     3061 attggatggt gacaacgtga tcgttcggaa gcaagaaact gctcaaaatg gcgatattgt
     3121 cattgcaatg actgccgagg acgaagcgac ttgcaaacga ttctataaag aaaaaaactt
     3181 tttccgtctg cagcctgaaa acgacttgct cgaaccaatc atcttagatc aagtatctat
     3241 attaggacga gtagtaggac tttatcgtag tcatatctat taattgctac taattaaaag
     3301 aaaacttttt aaaaagagtt tgagacgttg gtctcaaact cttttttcgc ccgggttctt
     3361 cttctttcaa atttttatca cttccctctt tacaaaccga acaaatattc gtatactaaa
     3421 tatacgaaca attgttcgca taaattaaag aggtgagaat tcatgaaatc aatgagacgt
     3481 cttggcttag tattaactgt tttgttttta ggtattatta ttggtaattt cggcatacgt
     3541 ccagctttac ttgtgtttgt tccgttattt actttgtggt tcatgttgtg ggatgaaaag
     3601 aagtaccgtc aatctgagcg gcgcagaatt catgaagatc atttctatca tgagccctac
     3661 tacagatcca ggcaatcata ataaggattg actgctaatt attcaaaaga caagaagtta
     3721 aacttttacg ggggtgtgac aaaaatcggt cacatccttt ttttcgaata aacggtgttc
     3781 taaagccagt ttttcggtat taagtcaaat tgcggaaaaa gtgatttttt aaacttctac
     3841 tggtctttgc ttgtttccat ttataaaaaa atagcgaccc tcaaaagtca gatagagaat
     3901 ctgacttttg agggtcgctt taaaatcgct tctttaagaa taacatcaag aatagcttct
     3961 tttttctgct taatattcca ttaatgtaat gatgtcatat cctttgattt tgtcgcgtcc
     4021 atggagatcc atcaattcga tcaaaaatgc gcagcctacg actacaccgc ctaattgttc
     4081 gatcagttcg atcgtcgctt tgattgttcc tccagtagct agcaaatcgt cacaaatcag
     4141 cacacgttga cctggtttaa tggcatcctt atgcaatgtc aatgtatctg ttccatattc
     4201 taatccataa gtcacttcga tggtttctcg aggtaacttc ccttttttgc ggactggggc
     4261 aaaaccgact cctaactcat aagcaacagg acatcctacg atgaatccac gggcttctgg
     4321 cccaactacc atatcaattc gtttttcttt tgcataattt acgatttgtt tagtagcttc
     4381 ccgataagcg tcaccatctg ccatcagtgg ggaaatatct cgaaacacaa ttccttttga
     4441 cggatagtcg ggaatactgg caatataatc ttttaaatcc actctttgtt tcctcctagg
     4501 ttgttaacca tttctttatg gtaggaatat cgctcaaaag caaaaattcc tcaactttga
     4561 ttttattgag ccgtcgctgg tataatctgc tctcagtcaa aggatgactt tctgggctag
     4621 cgactttttg taaaacaccg ttctctattg taacaaattt caattcaaaa aacacctgta
     4681 tcataaaaat taataatttt tcagggatac gcaaatattg agctattgct tttattttat
     4741 gacgtatatc aattcgttct tgagaatgga tcaatttaaa caattttgcg tactgttctc
     4801 ttgtgcctac cccattcaaa taggcctcat caggtgaaat ccccatcaga taaacacgat
     4861 tgaatgaata agaccgaaaa acttctttca gatccgctaa atcatctgga caatccataa
     4921 caactagaga gtttggtttt cttttttcaa ttattgcctt tacagaatct agtccttcga
     4981 aaacaatcgc agcttcctgg ataatctcag gcacgaattt caacgtcgaa gaatcaaatg
     5041 ctaaataaag gctaccttcc gacgttcggc tctgttcacg gaaacgtttt gcccgccaat
     5101 caaatacttg cagaccaccc acagaaaaat cagataccat cagctgcggt ttcttacgcc
     5161 cgttccattc attgatcgaa agctttccta ccacatctac ctgattattc agcagttctt
     5221 cttcttgagt accaaaacca aaagcgaccg catcaagctg actcgatgca tcggaaagga
     5281 caaatttcag atgctgttgg tttgctccga ttcttttgat attttctgct tggacttgtc
     5341 gaaataaaaa ctgaggcaaa ggattatccg taccaaatgg cgccaatagt ttcagctcat
     5401 caattcgctc tactgttact tcatttggca gcaatacttc atcaattctc aactcaggcc
     5461 ctctcatcaa gtcaatttga tgatcgacta tatattggtt catcttctcc tgtagtatag
     5521 tgacattttc acttggcatc gttaaaccga ctgctgcatg atgtcctccg aagtaagtaa
     5581 ataaatctcg catctggtca agcatttcaa aaagattcaa ggcttcaata ctacgtccag
     5641 atcctttagc tgatccatct tcttttaaag taaggacaag cgttggttta cccgtttcat
     5701 tcattatttt cccagcaaca atgcccaaaa cgccttcatg ccatcctcgg tttaccaata
     5761 gatggatatg attctcctta ttgaccatcg ctaatgcttc ttgtgttatc tgctctacga
     5821 ttgcttttct ttcttcattg atctcattca atttttttgc ttgaacggat gcttcctctt
     5881 catcaaacgt cgcaagtaac gagacggcag gacgtggatc gcccatccga ccgattgcat
     5941 ttagtctggg agcaatcgaa aaaccgatcg ttgtttcgtc tgcgtccctc atttttacgc
     6001 cgctttcttc aaatagcgcc tgaagtccta tccgttctga atgatgaatg gcatcgattc
     6061 ctaatgaaac aaggattcga ttctcatcag tcaatgaaac taaatcggcg atcgttccta
     6121 tcgctactaa atccaaaaat tctgcaggcg gttcttccaa taatgcagaa gctactttga
     6181 atgctactcc gactcctgcc aaatctggaa atggatagtg ccccgctgga tgacgagggt
     6241 gaacaatcgc ataagcgtct ggtaaattct caggtagttc gtgatgatct gtaatgatca
     6301 cgtctacacc agcttgctga gcgtatgcta ccgcatcatt tcctgctacc ccgttatcaa
     6361 cagtgatgat caactggatt ccttcttcga tcttttcttg gtataccgat tggtttggtc
     6421 catacccatg ctcaaatcga tttggcagga atacttctac ttctgcacca agtaattcca
     6481 gtgtttcttt cattaccgtt gcactggtga tcccatctgc gtcataatca ccgtaaacga
     6541 ggattttttc tccactgatt acagcttctt ggattcggct gattgcttta tccatatcgt
     6601 gtatcagata cggatcatgt aattcttgtt cctttggatg taaaaatcgg ttgatatcct
     6661 tttcctcatg gtaacctctt tgccacagta acttaccgac aaatggagat aatttcagtt
     6721 cacggatcat ttggagaaag gattcagaag gctctgtctc gcttaacttc caatcaaaat
     6781 ttgcttgtct cactttctca ctcctaactt agttattata gcaaaggaaa tcagcaaaaa
     6841 aaagcagaaa gaaagaataa aaacagatca gatccgctag acagatgttc agcaggacct
     6901 gatcttttgt acgaccattt atgaaatatc cctattagtc aaaataattg aagctttgtt
     6961 tgggcgattg agttttttgt tcttccggcg ctttcaattg actgatttgt gcggttttcg
     7021 cttgtaactc cgcctgataa gcagcttcca actccgcacg ttcgtttcta aactcgcgtt
     7081 gctgttcttc ttttgcttct tcaattttct tttgaagttc tgtttgatat tctgacattt
     7141 cctgagtcag ctgtttgatt tgcttttttt gctgccatag tgttgccgaa gcagtcaaaa
     7201 atacaatcag tgcaccaatc agcgcagaac cgatgatcac taagatcaat ggcgcagaaa
     7261 aggaagtgaa gccaaaactt acaggaacat ttttattgtt caatacagca aaaagaacaa
     7321 taatcaaaac taaaacaaat ccaagaatca cattgctttg ctttttcaat tccttcacct
     7381 actttttgtt aaaaattccg ctggctaaat aatcaccaat cgttggaaac agcgtataaa
     7441 attttgatgc aacttctaaa ataaacggtt gattgatttc ccgttttgga tgtctcatat
     7501 tgcggacgat catttttgcc aacttggcag gttctaaaac gatttgtccg actttttcca
     7561 aatagcttcc gcttggatca gccttatcga agaaatttgt ctcgattgga cctggattca
     7621 ctgtcgtaac agctacgcca agtggtttca attctaatcg caaagcgttg gagaagccaa
     7681 ggactgcaaa tttcgtggca gaataaaccg ttgattttgc agttgccatt tttccagcca
     7741 tagaggcgat attaatgata tgaccttgtc ttctttctgc catatcgatc gcaaattttt
     7801 gtgtcaaaac catcattcct aagatgttga cttcaaacat atcgtatgct tttccaaggt
     7861 cgaatgtaag gaagtcttcg aaaatcccaa aacccgcatt gtttaccaga atatcgacgc
     7921 gcccgacttc ttccatcacc ttttcatata attcgtccac gctttcagga ttgctgacgt
     7981 ctaccttgaa agcataagcc tctttgccgc tcaagcgtct gcactcgtct ctgacacctt
     8041 ctacaaatgc cattcttcgt gcgcaactta taacgattgc tccttgcttt gctgcttcat
     8101 aacagatttg tgcgcccaga ccgcctgaac tacctgttac taaaacaact ttatcttcta
     8161 aattcatgcc tcttcctcct cgcgaaatgg aatctcaatg ctatcaaaat ctttcataat
     8221 cgtcgtgttt tcaaacactt cttgtgcttc tttttcaagc tctaaagctg cttttcctaa
     8281 atatctcgca ctgatatgag taagtagcag ccgttttgcc tgcgcttctt ttgcaacttc
     8341 agcagcttga tgagtcgtgg aatggaaata gttgtgcgcc attcttgctt catctttatt
     8401 aaatgtgctt tcatgtacca gaatatcgct attttccgca agcacaacgg aattatgtgt
     8461 ttttctcgta tcgcctaaaa tagtcacgat tcgtcctttt ttatctggac ctacgaaatc
     8521 ttttccattg atcgtccgcc catcttctag ttggatcgtt tcaccttgct tcagtttgcc
     8581 gtacagtggt ccagctggaa tacctaattc ttttagacga tccacctgca attctccttt
     8641 atgatcatgt tcaaccacac gataaccaaa actgtcgatc ccatgattta gtttttttgt
     8701 ataaacagaa aattgctgat cagtaaaaat cggggctgtt tcatttagct caatgaattt
     8761 cagcggataa cttaaacgcg tttgcgaaat acctaaagag acttttatgt attcctctat
     8821 cccttttggc ccgtaaatct ctaatggcgt atccccacct tgaaatgacc ggctgctgat
     8881 gagcccggga agtccaaaaa tatgatcgcc gtgtaaatgt gtaatgaaaa ttttaccgat
     8941 ttttctcgga cgaatagtcg ttcgcaaaat ctgcatttgc gtgccttcgc cacagtcgaa
     9001 caaccaaact tcattgcgct cgtctaaaag tttcaatgct atacttgtca catttctatg
     9061 ttttgcagga acacctgcac ctgttcctaa aaattgtaat tccataatct acctgacttt
     9121 ctttaagttc ctctttaatt ttagggtaaa aagaagggat aatcaaccgt aagtcgagaa
     9181 tgggttcaaa ttaaaaataa cgttctaaag cgatagcgtt ttctttgaaa attactataa
     9241 aaacagcagc gaacccgttt gagatcctct gctgtttttt attaatttga agatccagaa
     9301 ctttcattgt cgttggaagt ttgcggatgt ttgtccttcc aagtcttttg tgcagcttct
     9361 ttcgcatgat tttcagcttc tttcgcatca tgcacatctt tttcgacatc ttcataatcc
     9421 aagcgagtaa tttctccgcc taattccatc attaccaatt gattcagtgg gcgattgtcc
     9481 tcttcatcag caatcaagat cagtcctgta gctccttcac cgattttatt tcctacaaag
     9541 tcgaacacgg tctgggcatc ttttatttct ttggcatctt gtgtcgcacc gatcattcct
     9601 ccggcaaacc atcctaataa aatccctagc ggaccaccta atacaccaac caacattccg
     9661 attaatccac ccgtagaaga tttgttatta ccggtaaagt cgataaaatc ttctattttg
     9721 aattgatgtg tcccattagg atcatggctg acaactgcca tctgttctcc tttaatcgaa
     9781 cgaacagcat gtaacttttt gatttctgaa aatgcctgat atgcctggct ttctacttga
     9841 aaatttaaaa tgattactcg tttgctcatt aaaaacgccc ctttcatacc ttcttgttat
     9901 ttattttacc tttaattgta aaataagaaa agaaaagcac tctttttttc caataaaata
     9961 gggctgtgac aaaagtcgta tcacagctcc tttttccgaa taaacggcgt tcttgaagct
    10021 gatcacttct gtcacaacct cccttaaatc tgaatctata ttttttggta tttgttttta
    10081 tttgcttgcc tattcgacaa attcaaattc aaactcaccg atacgtacaa ggtcgccatc
    10141 tttcgcaccg cgtgcccgaa gagcttcatc cacacccata ccacgtaatt gacgagcaaa
    10201 acgcatcact gtttcatcat gatcgaaatt cgtcatttgg aataattttt cgatcttctc
    10261 accagataag atccacgttg catctgaatc acgatcgatt tggaactcag gaccttctgg
    10321 attgaatcca tagtgtacag tttcttcttc cagttcttct tcgtacaatg ggaattctgg
    10381 cgttacttct aacaaatctg ctgtagcatt caataacgcg tccaatcctt gtcgagtcac
    10441 tccagaaatt ggaaatactg ggatgtcatc agcaaattca tcttcttttt ccttgttcag
    10501 ctgttctttg aatttcacta gattttccgg tgcatccggc atatccattt tgtttgccac
    10561 gatgatttgc ggacgctcta gcaagcgtaa gttataagta gataattctt tgttgatggc
    10621 aagatagtct tcataaggat ctcgtccttc catcccactc atatcgatca catgtaaaat
    10681 tactcgtgtt ctttcgatat gacgaaggaa ttgtgtaccc agcccaacac cttgcgaagc
    10741 tccttcaatc aagcctggca agtctgctgc ggcaaaactt ctgccatcac ttgtagtaac
    10801 cattcctaga ttaggtacga gcgtcgtgaa atgataagcg ccgatttttg gacgagcaga
    10861 tgaaataacg gatagtaaag tcgatttccc gacagatgga aaacctacaa gtccaacgtc
    10921 tgccaatact ttcaattcta gttcgatttt tcgctcttgt cctggttcac cgttttcagc
    10981 aatttccggt gcaggattcc gaggagaggc aaaacggata ttccctcgtc caccgcgtcc
    11041 accttttgcc acaactagtg tttgaccatt ttcaattaaa tctcctaaaa gagcaccagt
    11101 ctccgcatct cggacagtgg ttccttgtgg tactttaaca taggtatctt ctgaaccacg
    11161 accgtgcatc cctttactca tcccattttc acctggctgc gctttgaaat ggcgattgaa
    11221 ccgaaaatcc atcaatgtac gtaacccttc atcgacgatc aagatgacat cgccgccacg
    11281 accaccgtct ccgccagccg gtccgccgtc aggaacgtat ttttcgcgac gaaatgcaac
    11341 cattccgtct ccgcccttgc cagctttcac atcgatcgtt acttgatcta aaaacatgga
    11401 cataattaag tcctcctatt attcatttat ttatttgact gcctgaattt ccacaataaa
    11461 caaaagtctt acttatttta tcggtgaaat ctgattttgt ctatcatttc agcaaaaaga
    11521 ttgtttacct tcttcttttt ttatcatttg gtaaggtttc caaccttttt tctgctacca
    11581 agtataattt tttgacaaaa tattctttgc gtagcagaat aacagtgtat taattgtatt
    11641 aattgtatta attgaggatg ccgtttcaca gcacccctaa taaaggagga acttttgata
    11701 tgacagtaaa agtaggtatt aacggatttg ggcgtattgg ccgtctggct ttccgccgca
    11761 tcaaagaagt ctcagatgat attgaagtag tagcaatcaa cgacttaaca agtccaacta
    11821 tgttagcaca attattgcaa tttgactcta ctcatggtac ttatcctggc acagttactg
    11881 caacagaaga ctcaatcgta gtggatggcg aagcaactcg tgtttatgca gaacccgacg
    11941 caagcaaaat cccttgggca aaagaaaacg gtgtagatat cgtactagaa tgtactggtt
    12001 tttatacatc tgaagaaaaa gcaaaagcgc atttagatgc tggtgtcaaa cgagtagtta
    12061 tttctgcccc agctggtgct atgaaaacca tcgtctataa cgtcaatgat gatacattag
    12121 atgaaaacga caaaatcatc tcagcaggtt catgtacaac aaactgttta gcacctatgg
    12181 cttatttctt aaataatgaa tttgggatcg aagttggtac aatgacaaca gttcatgcct
    12241 acacttccac acaaatgctc ttagatggac ctgtaaaagg cggtaatttg cgtgctgctc
    12301 gttcagctgc tgacaatact atcccacatt ctactggtgc tgcgaaagca atcggcttag
    12361 ttatccctga gctacaagga aaattacaag gacacgcaca acgtgttcca gtcgttgatg
    12421 gttcattaac tgaattggtt tcagtattga aaacaaaagt aactgctgat caagtaaacg
    12481 aagcaatcaa aaaacacaca gttgacaatc cttcattcgg gtatgatgac cgtcaaatcg
    12541 tttctagcga tgtcattgga acaactcaag gttcgatctt tgacccaacg caaacagaag
    12601 taacaactgc tggtgatttc caacttgtta aaactgttgc atggtatgac aatgagtatg
    12661 gatttacttg ccaaatgatt cgcttactag aaaaattcgc taacttgtaa tttgatagat
    12721 caatcgataa aagaagcctt tgactggatc cagtcaaagg cttctttctt ttcatcccct
    12781 acttttaaac tcgttcaatg aacatattgg cttaaaaatt gttggactac ttgctgatat
    12841 ttttcaggat ctgtcttgta tgcttccgca tgctcggctc cttttacaac atacttttct
    12901 tttggtccct tcgttgcacg atagacctta tctaacattt caaatggtac aaatgtatct
    12961 tcgtctccat gtataaagag cattgggcgc tggtttttct tcaattgttc cactgcattt
    13021 gcttcaccga aaaagtagcc agcacggact tttgtcacta gactcgttac ttgcataagc
    13081 ggaaatgctg gaagactaaa catatcgtct agctgataag caagctcatc atgaacggaa
    13141 gaataaccgc aatcttcaat gattgctttc acattatctg gtagtttttc tccgctagtc
    13201 atcataactg ttgctgctcc catgctgaca ccgtatagaa cgatttcttg cgattttcca
    13261 ttgttttcta gcactttgtt tatccactgt acatagtctt tacgctctgg ccatccaaat
    13321 ccaatgtaat ccccttcgct ttttccatgt cctcttgcat caggaacaag gacattgtaa
    13381 cccatatcat gaaacatctt tgcgtaattg gtcatcgttt cagcgtttcc catatagcca
    13441 tgagccacaa gagctgtttt ttcacttttc gtttcagcag gaagataaat cgctgataat
    13501 ttcagaccgt cttttgaagt gatggtccaa tcgcttcggt tttcttttga actaaaccat
    13561 ttatgtgcat ccgtttcttt ggatgtctgt gttgtaccag gtgtatcttc gtctaaaaag
    13621 tctttctcag aaggcacaac agcataatta taaaaataat tccctgcaaa cactaacgca
    13681 acaatcagag ctaaagcgac gcctaaaagg attttcatcc aaagtttcat aaatcatcca
    13741 tctcatttct cttttttcat ataaccttga attagtataa tcaaagaatc tctactatgc
    13801 aatgttcatt tttataac
//
LOCUS       DACDLM010000070        13791 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.072, whole genome shotgun sequence.
ACCESSION   DACDLM010000070 DACDLM010000000
VERSION     DACDLM010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.072"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(115..450)
                     /locus_tag="IV356_002228"
     CDS             complement(115..450)
                     /locus_tag="IV356_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP9015892.1"
                     /translation="MGVEAVDKYLYLLAGNKIQKSLMDFIQELECTFHKKFTHSILLK
                     LLIHTACLIERTLINGHELKIISEDDTRPSHETIFHVKKAFKNIETEFGITVSYDECF
                     FIYDIIASK"
     gene            736..2616
                     /locus_tag="IV356_002229"
     CDS             736..2616
                     /locus_tag="IV356_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAP9015893.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIIIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDNVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDQFSQYYTPTVLLIALLVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQRGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAMLKQAGAKHLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLH
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSSFGSLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLIGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            2695..2922
                     /locus_tag="IV356_002230"
     CDS             2695..2922
                     /locus_tag="IV356_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper resistance protein CopZ"
                     /protein_id="HAP9015894.1"
                     /translation="MKKMIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSTKVKEA"
     gene            2927..3469
                     /locus_tag="IV356_002231"
     CDS             2927..3469
                     /locus_tag="IV356_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAP9015895.1"
                     /translation="MNIVEEKFAQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLKQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            3720..4397
                     /locus_tag="IV356_002232"
     CDS             3720..4397
                     /locus_tag="IV356_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HAP9015896.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATIATTTTTSTESKPTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSESSEQVEQTLWNADKSAQLEAFMA
                     TWGQTMGQQYKSYTNQMSVDLYGLKVPQVILNGEWKMAIGGVPVSAEWSESGTGQADY
                     QITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELKNG
                     FNQIVYG"
     gene            4718..5959
                     /gene="sstT"
                     /locus_tag="IV356_002233"
     CDS             4718..5959
                     /gene="sstT"
                     /locus_tag="IV356_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HAP9015897.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEPT
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            6106..6741
                     /locus_tag="IV356_002234"
     CDS             6106..6741
                     /locus_tag="IV356_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HAP9015898.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            6932..7675
                     /gene="truA"
                     /locus_tag="IV356_002235"
     CDS             6932..7675
                     /gene="truA"
                     /locus_tag="IV356_002235"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAP9015899.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYRS"
     gene            7909..8742
                     /gene="msrA"
                     /locus_tag="IV356_002236"
     CDS             7909..8742
                     /gene="msrA"
                     /locus_tag="IV356_002236"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAP9015900.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDTRENISVKEQ
                     LSKLEVTLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQDERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            8823..9816
                     /locus_tag="IV356_002237"
                     /pseudo
     CDS             8823..9816
                     /locus_tag="IV356_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L-glyceraldehyde 3-phosphate reductase"
     gene            10105..10803
                     /locus_tag="IV356_002238"
     CDS             10105..10803
                     /locus_tag="IV356_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HAP9015901.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNIA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNVLAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            10953..11408
                     /locus_tag="IV356_002239"
                     /pseudo
     CDS             10953..11408
                     /locus_tag="IV356_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016619852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            11489..12615
                     /locus_tag="IV356_002240"
     CDS             join(11489..11717,11717..12615)
                     /locus_tag="IV356_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAP9015902.1"
                     /translation="MTRYEENFKQMIIELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAGSHILSENLNSLVQFIEKWCKDYTVS
                     LLCRLLEIPRSVYYFYKNKPLTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKE
                     GISVSLKHVQKLMKQLNLRSIVVKKYRPQRSNKPIILKENLLNQDFSTETICEKWAAD
                     ITYIPTKKNGWCYLSSIMDLHTKKIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMIL
                     HTDLGSQYTAREVEQWLKTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDF
                     EEANRALFSYIEGFYNRNRIHSSIHYLTPQEFEELAKEKMA"
     gene            12660..13616
                     /locus_tag="IV356_002241"
                     /pseudo
     CDS             12660..13616
                     /locus_tag="IV356_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
BASE COUNT         4626 a         2225 c         2835 g         4105 t
ORIGIN      
        1 gtaaccgata cattagtttc aatgtttact gagtaactaa ttattttgca ggaggacaat
       61 ttatttacac aaaattattg acgctcccaa aatactcgtt tacataaaaa aagattattt
      121 agatgcgata atatcataga taaagaaaca ttcatcataa gaaacagtga tcccaaattc
      181 tgtttcaata tttttgaagg ccttttttac atgaaaaatt gtttcatgag aaggtcttgt
      241 gtcatcttct gatataattt taagttcatg accgtttatc aatgtacgct caattagaca
      301 cgctgtatga atcaaaagtt ttaaaagaat ggaatgagtg aattttttgt ggaaagtaca
      361 ttccaattct tggataaaat ccattaagct tttttggatc ttattcccag ctaataagta
      421 gagatatttg tccactgctt caactcccat atcaaaaaac gatatttctt gtgaatgagt
      481 ggctgctgcc cttttttgat tgttgttctt cagtcgtaag atgacaaagc atcttatctt
      541 tgaataaaaa aatagaacta cctaaggaag cgtttcggcg cttccttttt ctatatgatc
      601 gtttaatgac tgtaggaatt cagtatacca aaagaaaacc gcctttttga ataaacttga
      661 tagtggtcaa ttttttatga tggataagta tctatactta gtctcgtaag aatgaaaagg
      721 aaaagaggga gaaagatgaa attacaaaag tggatccaag agcatcgaaa tcatatcacc
      781 gccttatcag ctgtgttgat tatttttggt tttatcggga aatttactgg atttgtcttg
      841 ttctataaca ttgctctagc catagcttct attattgcgg tcatacctat tataatccat
      901 gcgtatcagg cagtaaaagt caaagttatc tcaattgatt tactcgttac tattgctgtg
      961 cttggtgcct ttatgatcgg agaatacaag gagtcagcta tcgttacatt cttgtttttg
     1021 tttggtagtt atctggaaca aaaaacattg accaaaacgc gggaatcaat caaggctttg
     1081 accgagatgg ccccatcgac tgccagcgtt gtccaagaag atggaacgac cgaagaagtg
     1141 gaaatcgatg acgtggaaga aggcgatatc gtcttagtaa aaactggtgg agctattcct
     1201 gtggacggac gagtcattga cgggaaaggg tatgcggatg aagccgcagt gacgggtgaa
     1261 tcacgacaag tcgtcaaaat cagtggagat aacgtatttt ctggaacgat tttagcagat
     1321 ggctacgtga cgatcgaagc aactaaggtc ggagatgata cgacctttgc caaaattata
     1381 gaattagtcg aagaagcaca agataccaaa tcacatgcgg aaaaattcat tgatcaattt
     1441 tctcagtatt atactccaac cgttttactt attgcgttgc ttgttggtct gatcagtcgt
     1501 gattttcgtt tagccatcac tgttttggtt cttggttgtc ctggcgcttt agtcattggt
     1561 gcgcctgttt cgaatgtagc aggaatcggt aatggagcga aacggggcat cttagtcaaa
     1621 ggcggtgaag caatggatac tttttccaaa atcgatactt ttgtctttga taaaaccggt
     1681 acattgacca aaggaactac tgctgtatcc actatcaaga actatacaga ggatgaaggg
     1741 gacagcttag ctttagtggc tcgattagaa acgttatccg atcatcctct ggggcgcgcc
     1801 gtgatccatt atgctcagga gaaagacatt gattttcaac aattagcagt caaagataat
     1861 cagacgatca agggacaagg aatcacagct gagattgatg gtcatacagt ttgtgcgggc
     1921 aacaccaaat tgattgccgc tcacaaactt tctctcacac caaagcaagt acaagattta
     1981 catcaattac aacaaagagg cagctcagtc attattgtag caatcgacaa aaaaatcact
     2041 caaatcattg gtgtgtcaga tgtgattcga ccagaagtcg ctgaacaatt agctatgttg
     2101 aaacaagcag gagcaaaaca tttagtgatg ctgacaggtg ataatcagat gactgctgat
     2161 tatgtagctg acatgttagg cattgatgaa gtccatgctg aattattgcc agatgaaaag
     2221 gttcaatttg tgaaaaaata ccaagaacaa ggattgcacg ttgctttcat tggagatgga
     2281 atcaatgatt ctccctcttt ggctgcggct gatatcggga ttgctatggg atcaggaacg
     2341 gatgtcgcta tcgaaacgag tgacgttgtc ttgatgcaat ctagttttgg atcgttggtt
     2401 catgcttacc gtttggctaa gaaaactgtt ttgaataccc gtgaaaatgt agtgattgcc
     2461 attggtgtcg tcttattttt actcatcggc ttatttgccg ggtttattta catggctagt
     2521 gggatgttcg ttcacgaagc tagtatcttg atcgttatct ttaacgcgat gcgtttattg
     2581 tattttggac acgaaagcaa agaagaaaaa tcgtaaaact tgataagaat caattttttt
     2641 atggaagctg taatctagaa taagactatc aagaaaaagg aaggaagaac tacgatgaaa
     2701 aaaatgatta tgcaattaga tacactagct tgtccaagct gtatgcaaaa aatagaacat
     2761 gcggtttctc aacagcctgg ggtaagcaat acgaaagttt tgtttaatgc gagcaaaatc
     2821 aaagcaaact ttgatccaga tgaagtccac cctgaacaat tagctgcagt tgtggaaaaa
     2881 ttaggttatg aagtccaatc aacaaaagta aaagaggcgt aaatcagtga atatagtgga
     2941 agaaaaattt gctcaagaaa caaaacaagc agatatcgat catcataaac caactgctgg
     3001 cgccatggtg gggcatgtat tggcaaattt taaattagaa gaaatgaaat tgatccaagc
     3061 acaattgtat gttttgggta catcttcgca agaattaagt accctttttt cagaatatgc
     3121 tgatcaagaa gcgagatggt tcaataaaat ctctcatgag ttagtgattg aaaatgaaat
     3181 cgttccgtct actttagaag aagtcatgcg ttatggaaaa atttacgaac atggtcaaaa
     3241 caaatattta ccagcctcaa caatgttgga aaactttgca aaagattttg atttccaaaa
     3301 tgtctttatc acacgggcaa tcaaattagc tgaaaaagaa gaaaaatatg gcttgaaaca
     3361 attgcttgtt gaacttttaa gtttcaataa agaaatcatc taccaagtac aaagactcca
     3421 aggaaaaact gtccgacaag atttggatga ggaagacgat gatgactaaa agtctatgtt
     3481 tcttcaaata caaatataaa gcgtgaggta aattggaaaa tcgcgaagat taaaataaaa
     3541 gaagcacccg ctgatgtatt acagacaaca tcagcgggtg cttcttagtt tttaaaaggt
     3601 ttaaaagatg gatgagaaaa tacaaaaaat caataaaatc acattgctta tttgatagaa
     3661 taaagaagtg ggagtaatcg aaaggagttt tttaatttaa aaaaaggatt ttagtaacaa
     3721 ttggtctagc ttttttgtta gctggttgta ccaacgggaa tgaatcgaaa aaagaatcaa
     3781 caaaagaaac agcgaaagca acaattgcaa ctactacaac aactagcaca gagagcaagc
     3841 caactgcagc aagtacggaa acagcagata cctctacttc gtcagagtct tccaaaacga
     3901 ctgaaacaac tcaaacatct acttcaagtt cttctgtaga ggcttcatct tcagaaagca
     3961 gcgaacaagt cgaacaaaca ctgtggaatg cagacaaatc cgcacaatta gaggcattta
     4021 tggctacatg gggccaaaca atgggacaac aatacaaaag ctatacgaat caaatgagtg
     4081 tggacttata tggtcttaaa gtccctcaag ttattttgaa cggggagtgg aagatggcta
     4141 ttggtggagt gcctgtttct gcagaatggt cagaaagtgg gacaggtcaa gcagactatc
     4201 aaatcacagc cgtctattcc gatgcagaga cagaaccata tctgaaaaag cacgtctatc
     4261 tattcgggtt tcagcaaaat cagccaaaag tattggtgac acaacaaaat caggggaatc
     4321 ccgataatta tctttacttt aacgagacag cgaataatga attgaaaaat ggctttaatc
     4381 aaatcgttta tgggtaagta aaccagtgag agtgagagaa agaagagact cagtggaaaa
     4441 tattaattga ttgctatgtc taagaattaa gatgaaggat gaaatttcta gtttcgtcct
     4501 tcatcttagt tacgttttac ttggataact ataataataa cgataaatag ttttctctcg
     4561 acttctttag agattgaata aaccctccaa tactaaaatt gaatgttgca agagcatgaa
     4621 ttgccaattg tattattaga atttttagaa aattgcacct ttagtttctt tagataaaat
     4681 gatacaatga ttgttaaaat tgtgaaaggg tggtcatttg ttagagaagt ttttggatat
     4741 gtcgttagtt caacgtattg ttgttggtat tttagtcgga atattgtttg gtatcttttt
     4801 ccccacgtgg acatttattt caatattggg gacgttgttt gtcagttgct tgaaggcaat
     4861 cgcacctatt ctggtttttt tcttgacgat ggcgtcaatt gccaagcata aaattgggaa
     4921 taagacattc gtgaagccta ttttgatctt atatttagtg ggaacattgc tttctgcact
     4981 tgtagcagtc attgtaagtt caatttttac tgttcctatt actttacaag aaacagtatc
     5041 tgaaaaagca ccgcaaagtt tggaaagtgt tttatctact atgttgacga atgtcacaca
     5101 aaatcctgtt caatctctta ttgatgcgaa ttaccttggc gttttattct gggctgtatt
     5161 gttgggacta gcttttcgag cacgttcaga accgacaaaa gagttggtgg atcagatatc
     5221 tatagcgttg tcacaagtcg tacaagtgat tattgcattt gctccgatag ggattttagg
     5281 attggtttat caatcaattg ctacgactgg aatcgctgga ttggcagagt atctgcagct
     5341 tttacttgtt ttgatcggta cgatgctgtt tgtcgcatta gttgtgtacc cattcctcac
     5401 gtttttgttt attaaagaaa atccctatcc attgattttc ttttgtttga aagaaagcgc
     5461 acttcccgct ttctttaccc gaagttctgc cgcaaatatc ccgataaaca tgatgttggc
     5521 tgaaagattg aaattgacaa aagagtctta ttccatatcg atcccgttag gtgctacgat
     5581 caatatgggc ggtgccgcga ttaccatttc cttgatgacg ttgactgctg tacattcttt
     5641 agggattgaa gcaccatttg ttttgaaagt ccttttatgt attttgtctg ctttagctgc
     5701 ttgtggagct tcaggtgttg cgggcggttc actgttattg attccattag catgtagttt
     5761 gtttggtatc tctaatgatg tcgcgatgca aatcgttggt attggattta ttatcggtgt
     5821 tatccaggat tcaatggaaa ctgccttaaa ttcgtcaagt gatctgttgt ttactgcaat
     5881 aggagagcta ggcgcgcgta aaagaagtgg ggaaaaaatc aaattgaaag attgtttaga
     5941 tggattaagt gaacgttgaa cgttagatat ttagtatttt taaaatgatt cgagttttta
     6001 atgagttata tagatgttcg tgtaaataga ggtttctgtt aaatcaagat aaagtcgttt
     6061 ataataacaa ttaaaagcat aggtaattgt tattggaggc gtatcatgga ttttttacgt
     6121 aaatttggtt ttttcttttt attattaggc gtgctgagtg attttttgac tccgtacgta
     6181 ttaggattgt attatcctga attagatcaa atgaagagcg tgatcagtgt atttggagag
     6241 gtttccagtc ctgtaagaaa agcgtttctt atttggtctg tggtttcagg gatctttttc
     6301 atcctgtcat tgcctgcatt gtatgctgca tttgtaagta catctcgtgt gttagctacc
     6361 ctagttacag cagccatcgc gttctatggt ataggtgatt gtatctttac aggtttgttc
     6421 agtatcaata cccatgaatc ttcgtggaat gtctcgacat gggtccataa tatcggatca
     6481 ggtttaggtt acagtggttt tttattgttt ccagttcttc ttttcttgat ctatcgaaaa
     6541 aatgggcaaa tggacgtaag ccacttatac cttggactgt ctgtgatcag tttgcttttt
     6601 gcggcgattt atggactggc aagaattcct tctataaatt cttggccatt actgaataaa
     6661 ataggttttt gccaaagaat cagttttttc tttaattatg tgcccattgc ctggttgagt
     6721 atcttgcatc tcaaacagta aaacttgagc cgtcaaattg aacagtcagc ggatacttca
     6781 tccggtggct gttttttgtt tttctgaaat atatatttcc acagttttct tgtatagctt
     6841 ctgtcttaga gaagcaagga gctatatttt gtgctacaat cttaaaaagg tagagagaag
     6901 accaaatgga agacagagga gccactaaaa tatgagaaac atcaagttga caatcgaata
     6961 tgacggaaaa agatattcag gatggcaaag acttggagat gacgataaaa ccattcaagg
     7021 aaaaatcgaa aaagtattgc atcagatgac aaatgaagag atagaaatta ttggatcagg
     7081 aagaacagat gctggcaccc atgcgcgagg acaagtagca aattttaaaa caaacacaga
     7141 aattggactg gcagaaatga tcgactttat gaatcgttac cttccgcggg atattgtcat
     7201 caaaagaatc gaagaaatgc ctgagcgctt ccattcaaga tataatgcgg tgggcaaaaa
     7261 atacagctat tatgtttgga acaacgtgat tccttcagca tttgagcgaa accacagctt
     7321 ttatttccct caagagttgg atatggacaa gctgaatgca gcttgcgaaa aattagtggg
     7381 tacacatgat ttcattggtt tttctgcatt gaaaaaatca aaaaaatcca cagtgcgtac
     7441 gattgatgaa ttatctatcg aacgaaaggg agaaatgctt cattttactt ttgtcggaga
     7501 cggattctta tataaaatgg tgcggattat catggggaca ttactagaaa tcggcacagg
     7561 tgccatgccg atagaaacaa tcgatgaaat atttgaaagc aaagtgcggc aacatgcagg
     7621 agaaaccgtc cctgcacaag gtctgttttt ggatgaagtt tattatcgct cataaaaaag
     7681 aatcatcttt actcgacttc tgagaattgg agaacatccc ttttttcaga ggtcgttttt
     7741 tagttaaacc aaaccataga gtatgctttt taagataaag atcatcttat atcatctgaa
     7801 gctgcttatc ttctttgaat aaatacgatt caatcgatta tttcctcact ttatgataaa
     7861 ttacagctaa agtcactagc ttgtcttctt cggaaaggag gagaatctat ggatgaggaa
     7921 caaatattca ttcaaacact ttataatctg attttgaatc cgaatacacg agattgggaa
     7981 cgaaaagtat tgattcagac aaagaatgac acaagagaaa atatatccgt taaagaacag
     8041 ttatcaaaac tagaagtaac actacgtcca ttagctatcc gaatgaatct gacgcctgat
     8101 gtaatggact tttatttatt gattacggaa ggatttgata aggagcaaaa atatgacttt
     8161 tccaagcatg ccatgcaaga tgctgactat caagaacgtg cagtatttgc agggggatgt
     8221 ttctggtgta tggtcgagcc gtttgaatcg aaaaaaggga tcctatctgt tttgtcagga
     8281 tacacgggcg gacatgttga aaaaccgaat tatgatcaag taagtggtgg ttacacaggt
     8341 catgtggaag ctgtggagat catttatgac acaagagaaa taagttatag cgagttgctg
     8401 acaatctatt ggcaaattac tgatcccaca gatacatttg gacaatttca agatagaggg
     8461 aagcaatatc gtccagtgat tttttatcaa gacgaacgac aaaaagaatt agcggaacaa
     8521 tcaaaacaga aactagacag ttcaggaact ttccaccaac caatcgtcac aaaaatcgaa
     8581 ccagccggta cgttttggcc agcagaaaac tatcatcagc aattttacaa aaaacaaccg
     8641 aaacgctata aaaaaatcca gcaagcacgt aatcaatttc tgatctatca acgagtaaaa
     8701 aacaaatggc aaaaaaatat acgaaaaaat cattttgatt aactcctttt ctttaaaatg
     8761 tagtaaacta aaaatagaaa acaagaaagc gttttaaaaa gatttgatga ggaggagaaa
     8821 aattgtatat tgcagatagt gcacgttatg aaaaaatgga atatcgtaaa tccggtcatt
     8881 caggtttaaa attaccgatt ttatctctcc tctcggatta tggcaaaatt ttggtgatta
     8941 tgatcctatc cataatcaaa gagagatttt aagaggcgca ttcgacatgg gaattaccca
     9001 tttcgacctt gcgaataatt atggaggccc tgctggagct gcagagaaaa actttgggcg
     9061 tatttttaga gaagattttc aagcctaccg tgatgaactg attatttcta gcaaagcagg
     9121 ttatcatatg tgggaagggc catatgggga atggggctct cgtaaatcca tcatatcaag
     9181 ttgtgaccaa agtttccaaa gaatggggct agattatgtt gacatcttct atcatcatcg
     9241 cccagaccct gatacacctt tggaagaaac agcagaagcg ttgatgcaac ttgtaagaca
     9301 aggaaaagca ttatatattg gtatatccaa ctataatgga gaagatacaa aaaaatgact
     9361 gaaattttaa aaagaaagga agcaccgttc attattcatc agatgcgcta caatatgttt
     9421 tctcgtgcac tactagaaga cgatctatct ccagtattag aagaagaagg gctaggggca
     9481 atcacgttca gtccgcttgc tcaagggttg ctgacaaatc gttatctaca tggtattcct
     9541 gaagattcta gagcacatcg taaggaaata ccattccttt cagaagaaca agttggatca
     9601 actctggaaa aaatcaaagc actgcaaaca atcgccgtat cacgaggaca atcattagcg
     9661 caaatagccc ttgcatggaa tttacgacaa aaatctgtta caagtgtact gatcggagca
     9721 agtcggttaa gtcagttaca agaaagtgtt cgaatgatgg ataatttaga tttctcacca
     9781 gaagaagaat tgagaatcga ccaaattcta gaatagaaac gatgtaatca aactttttat
     9841 ccatatatta aaaaaaacaa aagatgacat caagaatcga atgaagatcg tctgttattg
     9901 aacatcatat tttttgtcga tcaaaataaa aatgatcgaa ggctaggagt gaattttatc
     9961 ctagtctttt ttatggtaaa tatcttcttc gtttgtatgt ctatgaacgg attaatcgat
    10021 tttttataca aaaaatcatc agatgattca aacgtgttat aataattacg aaaaaataca
    10081 tcagatgaaa aggaggtatg tggtttggaa gaaaataaaa ccctagtaga agtaactact
    10141 gacaagatcc ttagatattt aaaggaaatg cagttgcaag taggagataa actgccgaat
    10201 gaatatgaat tgtccgatta tttagaggtg gggcgaagca cggtgcgaga agctgtgcgg
    10261 gctctagctt ccaggaatat ccttgaagtt cggcaaggag cggggacatt tgtcagtgat
    10321 aagcgaggga ttgccaatga cccactcggt ttttctttga ttgaagatca ggatcggatg
    10381 atacgagact tatttgaact gagatattta ttggagccta agatggcagg tttggcagcg
    10441 gaatatgcaa cgaagaatca aatcgtccaa atgaaaaaat taacgcaaaa gattgaaact
    10501 tcttttcgag aaggcacaca agaacatgtt caattagaca tcgattttca tacgatgatt
    10561 gcagaagcta gcggaaacat agccttgctg catattatcc caatcattaa tgaatcgatt
    10621 gctttgttta ataaaaatta tgatatccag catctgaaaa tcgagacgat cgatattcat
    10681 acagagatcg ttcaggccat cgaaaggcgg aacgtacttg ctgcgtttga cgcaatgact
    10741 gtccatatgg caataaatcg gagagaatta cagaaaataa taggagaaaa agaaactaat
    10801 tgacagttca tctgatgtat tttatgataa atacatcaga tgattttttg ttttatattt
    10861 ggtaaaaaag aggagtaaat agtttctgtt caccaaaatg taagcgctga ctaatagaca
    10921 aaaagagatg acgtcaagga gaagaagcag gaatgagggg atctggaatg agttttatgg
    10981 ataaattagc caaagtttta gggaacgtgg caacgagaat caataattta aggtatatca
    11041 tggtgataaa aaacgcattt gctgcattga ttccggtaat tattacgggt gcttttggca
    11101 cattgttttc agcaatggtc tttgactcgg aaaatggctt agcacagata agttacttgc
    11161 gttttttaga agaattaaag cctatcgcat ctgccatcag ctatgtcaca ctaagtttct
    11221 tgaccatcta tgctgttttt ctaataggga tcgaattagc caagctgaat aaagtggatg
    11281 gtgtattccc tggtatcatc gcagtgatgt cttatttatc tgttaatcca actgtttatg
    11341 aattagtgaa tgaaaatcag actgttatag tagaaaacgt attggctaaa caatatacag
    11401 acacgaaagt ggtgttagta tcaaatctta gacagctttt cgtagagaca agaataaatt
    11461 aaacttatct acgagaggat gaatttttat gacccgatat gaagaaaatt ttaaacaaat
    11521 gattattgaa ctgaatcaaa ctggacgttc tgttcgaggg ttagcgaaag aatatggctt
    11581 atctgaagca acgatttaca aatggaagaa tttatattta cctgatcagt ccacaggact
    11641 gactggaaaa gaagtagctg aactgagaaa agaaaatgct cgtttaaatg aggaacttga
    11701 aatcttaaaa aaagccgcag ccatattctc tcggaaaacc taaattcgct tgttcaattt
    11761 attgaaaaat ggtgtaagga ttacactgtt tctttgttgt gtcggttatt agaaatccct
    11821 agaagtgtct attattttta taagaataaa ccgttgacag ctacagaaat cagaaataat
    11881 aagttgaaaa agaagatttc aacaattttt tttacgaata aacaacgcta tggtgccaca
    11941 aagatccatc aagttttatt aaaagaaggg atttcagtat ctcttaaaca tgtccaaaag
    12001 ctaatgaaac aattaaattt aaggtcgatt gtagttaaaa aatatagacc tcaaaggtct
    12061 aataaaccga tcattttaaa agagaatctc ttaaatcagg acttttctac tgaaacgatc
    12121 tgtgagaaat gggcagctga cattacgtac attcctacta agaaaaatgg ttggtgttac
    12181 ttatcttcaa tcatggattt acacacgaaa aaaattatta gttatacatt ttcaaaacga
    12241 atgactgtgg attgtgtcat tcaaacattg aataaagcaa aaatacatta tcacattcca
    12301 gaaggaatga ttctacacac tgacttgggc agccaataca cagcaagaga agtggaacaa
    12361 tggcttaaaa ccaacaaaat aaggcattct tatagtagaa aaggaacacc ttatgataat
    12421 gctggaatcg aatctttcca tgcctcattg aaaaaagaag aagtctacac gactagctac
    12481 tcagattttg aagaagcaaa tcgagcgcta tttagctaca ttgaaggatt ttataaccga
    12541 aatcgaatcc atagctcgat tcactatcta accccacagg aatttgaaga attagcaaaa
    12601 gaaaaaatgg cttaaccgtc tctactaaaa tgtgtccaag atattgactc aaatccattg
    12661 atcgttacgg tgatagggta aaaaactggt ttacattcaa cgaaccaatc gttccccaaa
    12721 cgcgttgcta tttggatgct gttcgctggc cgcatgaaca aaacacaaaa aagtggatga
    12781 tgtggaatta tcataaagtt ttagcaacgg ctaaagcagt agagatttac cgcagcggaa
    12841 attatggtgg aaggattggc tgtattttaa atcctgaaat ggtctatgct cgatctaatt
    12901 ctccagaaga ccaaaaagct gcttatatgt atgatttgtt ttataatcga gtattttttg
    12961 atccgatggt aaaagggtac tacacagaag agttcctgga gttgtgtcaa aaacaatcga
    13021 tttatttcga tcctgcaaca gaggatttag aaacgattca gcatcataca gtagatttcc
    13081 ttggaatcaa tcaatattat cctaaacgcg ttcgcgctcc tcgttatcaa tggaatgaag
    13141 agacaccttt ccatccagaa cgatattatg aagtctttga tttacctggg aagaaaatga
    13201 ataattccag gggatgggaa atctatccga aaatcatgta tgatatagcc atgtatctaa
    13261 aagaaaatta tcataatatc ccttggctga taacagaaaa cggtatggga agagaacatg
    13321 aagaacggta tatggatgag aaaggaatcg tgcaagatga ttaccgtatc gaatttatcg
    13381 gacagcattt gcgttatttg atcaaagcaa cagaagaagg cgcaaattgc gaaggctata
    13441 tgttatgggc attcactgac tgtgtgtcac caatgaatgc atttaagaat cgatatggat
    13501 tagttcgaat cgaattgaac gatgaacgaa gcagaacatt gaaaaaatct gcttcgtggt
    13561 atcagacttt gattgataag agagaattgg atttgcctga cgaaatctat aaataaatag
    13621 aagttttttg tagatgttca ttgtatttac tggttatttg aaataaaaga ggttgtgaaa
    13681 aagctgtcct gcatcaagta ataagaatag caaagtaaaa acaacatctt atgtttttaa
    13741 cttggttgga cttattaccg cagatgcaag cttttgaata ccgtttattc g
//
LOCUS       DACDLM010000071        13735 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.073, whole genome shotgun sequence.
ACCESSION   DACDLM010000071 DACDLM010000000
VERSION     DACDLM010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.073"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(63..1268)
                     /locus_tag="IV356_002242"
     CDS             complement(63..1268)
                     /locus_tag="IV356_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAP9015903.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            complement(1291..1444)
                     /locus_tag="IV356_002243"
                     /pseudo
     CDS             complement(1291..1444)
                     /locus_tag="IV356_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(1447..2832)
                     /locus_tag="IV356_002244"
     CDS             complement(1447..2832)
                     /locus_tag="IV356_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAP9015904.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            complement(2861..3247)
                     /locus_tag="IV356_002245"
     CDS             complement(2861..3247)
                     /locus_tag="IV356_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAP9015905.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            complement(3263..3577)
                     /locus_tag="IV356_002246"
     CDS             complement(3263..3577)
                     /locus_tag="IV356_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAP9015906.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            complement(3930..4409)
                     /gene="rlmH"
                     /locus_tag="IV356_002247"
     CDS             complement(3930..4409)
                     /gene="rlmH"
                     /locus_tag="IV356_002247"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HAP9015907.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYGLAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            4837..6126
                     /locus_tag="IV356_002248"
     CDS             4837..6126
                     /locus_tag="IV356_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAP9015908.1"
                     /translation="MDRKNVTPKMKKNKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVMMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(6165..6770)
                     /locus_tag="IV356_002249"
     CDS             complement(6165..6770)
                     /locus_tag="IV356_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HAP9015909.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVASYGMICSARELHLPNAPEKKGILVLPEDAVVGEVFPK"
     gene            complement(6966..7430)
                     /locus_tag="IV356_002250"
     CDS             complement(6966..7430)
                     /locus_tag="IV356_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAP9015910.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKALEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKQMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYAIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(7452..7772)
                     /locus_tag="IV356_002251"
     CDS             complement(7452..7772)
                     /locus_tag="IV356_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAP9015911.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VIKG"
     gene            complement(7915..8994)
                     /gene="pepA"
                     /locus_tag="IV356_002252"
     CDS             complement(7915..8994)
                     /gene="pepA"
                     /locus_tag="IV356_002252"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HAP9015912.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            9194..9544
                     /locus_tag="IV356_002253"
     CDS             9194..9544
                     /locus_tag="IV356_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAP9015913.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKTSFLKEGAIEGAWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLDISRKKGAID"
     gene            9729..10682
                     /locus_tag="IV356_002254"
     CDS             9729..10682
                     /locus_tag="IV356_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP9015914.1"
                     /translation="MESREKIAVLIPCYNEEATISTVIEDFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAAHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVKNTITYLYKTKIRDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMCKDYKPLLFFGIWTIFFFLFGLVMGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYQNKEMK"
     gene            10695..12482
                     /locus_tag="IV356_002255"
     CDS             10695..12482
                     /locus_tag="IV356_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015915.1"
                     /translation="MHKKKENLFPTFFATLFASGFAFFTSYGLGTLNPTVIIGLAMVL
                     LLAFKQYGIELFSIKNKVAAIARLFFSAAFALTLSIGRQIQFQYVSANYTKTTIADGS
                     IFYFLVYFSIFVYSFLFLQSIYLSMPKLETFFTAQNTQAFSSRKYFLFFTVFLVLCWL
                     PYLLALYPGVVLPDSLSSVAQSMGDVPISNHHPVLFTLLVKLFVHDLPTDTINHGVFL
                     FSIFQTLITASAISYSLCWLLKRNIHFFPVLISLCYFAFAPVFPIYALNMQKDTLFSI
                     ACFLFSLAVFDFIFQREKPTILNQIYVIILALLTTYLRNNGIYVVTGTGLICGLIILK
                     QKRYQAFFQVVLGYTVIAGLLIHPLMARYAIPTETAEQLGVPLQQISRTIVMDGDLSK
                     KDKAFMNQLLPIKDYEAYSPSLADSIKWHKNFNNEFLNTHKKEFLSLWARNLPSNIKI
                     YTDAYILETFGFWVPGTKNSYGFLDTRVNTNNYGMKQVDLIEHLTGLSGMKKIIDARD
                     FFGSGTLLWLAIGSALLAIFKKKYRYLLLFLPGMLVFATIMIATPVAFSLRYVFVLAL
                     GLPVYILSPFLLDKREKMKTDIGDTHETI"
     gene            12469..13671
                     /locus_tag="IV356_002256"
     CDS             12469..13671
                     /locus_tag="IV356_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015916.1"
                     /translation="MKLFKKIFFAFVLLIASYCVLLTITFFIPQHSIESNAEKSLQMV
                     EKEGMYPSINQGNMLGTRLDNFTDHLMIRKTKADPELNSLENAMSMADYPRYWHGYQL
                     FLRPLLLGMSLGSIRMIYAAILFLLIGLTSYFLTKCSDIYLTTALLISLAIGNAATFF
                     FSMQFSNIWILTLLSVLLFLTKPQLSNTNQQLFLYFFVIGSLANFFDLLTTPVISWGI
                     PVIIIYYVTNKYLMDKRSSLSKQVGSFVFTGIFWGLGYGLTWVAKWILSSIILNKNIV
                     KDAINQILFRTEGNDKYPLHRLEMLKSNIRLMYPKVAILLLLITCLVFLYFAYRKRNS
                     WRPFQLLVLFVLAAVTPYIWYNILANHSQIHYWFTYRTQIITSFAILSAFAFLIPPEK
                     SKDELNYF"
BASE COUNT         3938 a         2689 c         2520 g         4588 t
ORIGIN      
        1 aggttttgtc caaaattcat aaaaatgttc tcctctctat attcaatgaa tttgtatttg
       61 agttattttt ttgttgttat cacgtcctgt tcttttactg actgttgctt caaaatctgc
      121 ttgtgtcggt ctgtcagttt cgcatggtcg agaatgtctt ttacaacctg cgtctggttg
      181 atttcatcaa gtttaatcgc aacctttaag gtcggggcaa cttgatgaga tagccagttc
      241 agcgtccttt ggaaggagta aggctctggt tttgtggtta gttttaatcg ttcacgattg
      301 ttcccaataa accaagccca ttcttcattc agtttccaat cagaacgagg tttggaatcg
      361 tctttatcta caaaacggat ataccgattg ataattttaa aggcggtatg ctctggattg
      421 tcatagacga gtaaatcacg gactgcataa taggcacgct catttttcaa tcgaatctca
      481 aaacggtttt ttacttctgc gtcttcaatg ggaatatcat ttttcttgta ctgctcgtag
      541 tccttttcat agatacagaa ataaacttca ctttgtaatg aaccgatata gagggtgttt
      601 cccatacatt ccttttcctc tttgcgtacc agttcgccac tgcgatagct tttaaaactg
      661 cggaagacgg agatacattc ttcctgttgg cacttttcag tgagtacagg gatatttaaa
      721 atccctgtct tatcgttaat ggcaaggtca aggcgtttca tcacaccgcc agccaccaaa
      781 acgtccataa agaactcata ccagcttctt tgttgtgcca gaagatagct ttcaaattgt
      841 ctgcacccac gacctttcaa ttccaccaga actcctttgt ccagttcatg ggagcaaagg
      901 acgaatatgt cgcctaaagc ataatgctct gaataagaat agaaaccata gtcctcatga
      961 agaaaatagg acagtttcag ttgtaagatg ttttcgacca cctgctgtac gtctgttgtc
     1021 ggaaagcgaa ttcttacata atcaaacagc atttcaaggg gagcgtcggg attgaagcgt
     1081 tccagagctt cccaaaggga ctgctgtaaa tcctctgatg gcttgacttt tcctgtttca
     1141 atatcgctta gatactgcct tgtaatacca gtcgcaacag ctaaacggtt ttgagatagt
     1201 ccataagcca agcgtttttc ttttaaatgc tgtaaccaag tttgttcatt cagtaaaaat
     1261 ccctccaatc aaaaaggcgt atgtcaactt ttaaagccca tttgacatac gctgaaattt
     1321 tgtaaatccc ttgtaaccaa aggattttct aatgtttttt tgactgtttc ctgtcgattt
     1381 gtacccccct gttagatacc gaggggttaa gtgctggcgt ggctattgcc acaccagcca
     1441 gcaagatcag tccacacctg cgacttccgc ttcgcacgtc gcctgcgtgg actgtctgct
     1501 gttggataac tttttaattt cctccaagaa atcatatcct tttggtacaa ggggagtata
     1561 aaactctgat atgacacttg ttcctacatc aacatagcca cgacctttga ttcgctttaa
     1621 gaagaaatcc ttttgtacgt cactgccaaa catcatgcca tagcccattt cagacatacg
     1681 acctaaagcc actctgaaat taaactgatc acggattccg tcgcctaaat attttgcgtc
     1741 tggacgttga caagccagta ttagaaagaa gccagcttga cgacctaaca tgacaatctg
     1801 tttcagctta ttcataactg cggtgttttc ttttgttccc agcatttcca tgaaagcgac
     1861 gtattcatca aagattaaga agtgtgccgg gagacctaag taagcataat ttttgccagt
     1921 cttatagttc ttcatctgct tcatttcctc actacgtttc atcatttctt catagaatgt
     1981 ttcaatgcaa gaaagcaagt cttcttttct atagtagaca tttgccatca cagaacctaa
     2041 gtccgcaagg tcagcatttt tcgggtcaag aatatacagt tttgaatctg tatgaagcaa
     2101 ggcttcaatc agtgtcagta taaagtaagt tttaccgcca cctgtaccac cagcaatcaa
     2161 catatgaggg agcttatcat attcccacca tacgtttttc attaagcgaa gtttaccatc
     2221 tttagcttct acttcatcaa tagaaatacg actggctatg gtgtcataga gcaaagtata
     2281 ttccacatag gaatccttta actctttatc cgtcagctca cagtacaagc cactctctaa
     2341 tttcttttcc aagtgtaaga gttggtcttg atattttccc agcgtgattt ccacccgtat
     2401 ctgtatcaag ccatttttaa gtcgataata cattttaggg aagtaggtta tcttttcctt
     2461 tgtacgacca gcactatctt taaagaaacc ctctgttttg acctgttcag attcatacca
     2521 cttgttttca agtatcatct ttgccagttt ttgacggtgg taaagttgtt taaccgtatc
     2581 atagcgaacc cgtttgaata caaacgctac cagcaagcag ataagaattg cgacactgaa
     2641 actgataatt aaatagggaa tgtcaatctt atctgcttgt gataggttaa aatcctgcca
     2701 gttgatctgc tggattgtct tcacatgaaa cagtccgaca accagcagga aaacaggcag
     2761 gagtgacgct atcgtaaaat gaaagactaa atctttacca gatgggcgaa tccttttacc
     2821 acgctgtttc atgcgaaaaa gtctcctttc tacctagcga ctatttgtct tgtgtcggtt
     2881 ctttctttgc ttgtggttga gctttgaatg aactagaatc ctttgtcagc acaatatcgt
     2941 ctgccttgat ataccagtca acatctgctc cttgataggt ggcagtagca acggtgtccg
     3001 caatgggatt gataagttcc acccgtgcgt tataatcaaa ctctttcaaa ggcacgctgg
     3061 caggaatact tacttgaatc atgcgtcctt gtcctttgga ttttaagtca taggtacgtt
     3121 ccttgatttc atctgaaacc gacccgtctt cattttggat tctcacttca cgacgtagag
     3181 cagagaattt caattctcca aaagtcgtgt ctttatctaa tacaatgcca tttgctaatc
     3241 tcatcatttt tcctctcttt ctttattctt ttatcatgtc gtcagcatgt aaaaggtaat
     3301 ttgtaaaacc acgagtgccg attttgtagc cctctgcggt aatacgtgga ttgactaact
     3361 tcacacgttc ctcaaagccg aaatgttttt cgccagcttc agcaggaagc accaccacaa
     3421 tatcatctgc tctttgaaca tcagaataga gattatagct tcttgataag acagttagcc
     3481 gtccgttgat tcttcgctga acgactttat cctcgccagc aaattctaaa ttgccgaatg
     3541 ttttttccat gttgggaatc acaaatttaa gttccatatt tttacctatc ctttcttttt
     3601 tattggctga atgaatgttt gatggtctta aagagtgggg aacgaccttt tgattcttga
     3661 ttttttgttt tcataagttc acttcctttc aaaatcgggt aaaaaaatag acacctcatt
     3721 ttttgaagtg tctacctatt aaatattcaa attttattgg aagtatcttt atatcttcac
     3781 ttttcaagga taaatcgtcg tatcaaagct cattcataag tagtaaatta gtagtaaatt
     3841 gagtggtttt gaccttgata aagtgtgata agtccagttt ttatgcggat aactagattt
     3901 ttatgctatt tttctcttaa aaaatatcat tatttgtggt atggagcccc cgcgttgatc
     3961 cggaaggcac ggtagatttg ctcgacgagg atcaggcgca tcaattgatg tggatacgtc
     4021 attttgccaa aagagatctg agcattgctt cttttcatga cggcttcgct gagtcctaaa
     4081 gaaccgccga taacaaaaac aaggtggctt tttccttgga tacctaattg gtcgatttgt
     4141 ttagcaaaag attcgcttgt gggatttttc ccttcaattg ctaagccata gacgtattct
     4201 tgttctttga ttttcgctaa gatccgttct ccttcttttt cttttacttg tctcatttgc
     4261 gcttcgctta aattctccgg ggctttttcg tcaggaactt cgatcaattc gattttcgca
     4321 taggcattca gccgtttgac atactcattg ataccttgga tcaagtattt ttcttttaat
     4381 tttcctactg aaataatttt gatattcatg ttttctctcc tttgatcttc acgctcactt
     4441 tgtttattat aatcaatttt ttcgtctata tgtttatttt gactattttt gttaaaaaga
     4501 tttccccaac agttatgcac aacatccaca ggtttatcca cagaaaacag cgttgtttta
     4561 ccttatttca tcacattcat taggcaaaca tacgttttat aagaatttat ccactttata
     4621 cacaggctgt ggatatgttt tatcccttat ttttccaatc ctatccgcgt agttttacac
     4681 aatatctgtg gaaaaagaaa atcaaatatt ttcatctgaa aacaatgatt tttcctaaag
     4741 tttttcataa aaagttcaaa gtctcaaagt agactaaagt caacaaataa gactatacta
     4801 acagtagata aatgaatgta attggaggag gaacacatgg atagaaaaaa tgtgacacca
     4861 aagatgaaaa aaaataaaaa taatagcctc tggcgtaagt tgggtctggg gcttgttgga
     4921 gggatcgttg gaggactact gacagctggc attttttatg cagcgatggg cactggcaac
     4981 aatagttcta ctgctacaag cggcaatcaa aattctgccg gtgaaacagt tgtggaaaat
     5041 gtcaaagtca atgtagattc tgatatcacc aaagcggtag ataaagttca agacgctgtc
     5101 gtttctgtta tcaacttaca aagtcaaaac caatcaagcg gttttggcgg attattcggg
     5161 cagcaagaag aaagtagcag ctcagatgat agtaatttgg aagcttatag tgaaggaagc
     5221 ggcgtaatct acaaaaaaga cgggaatact gcttatgtag tcacaaacaa tcacgtagta
     5281 gatggacagc aaggtttgga agtcatgatg aaagacggta cgaaggtaaa agctgaatta
     5341 gttggaacag atgcctattc agatttagcg gtgttgaaga tcaattcaga caaagtcgaa
     5401 acggttgcct cttttgggga ctcaagtgct ttgaaggttg gtgaacctgc gattgcgatt
     5461 ggttccccat taggatctga atatgcgaat tctgtcactt caggaatcat ttcttccttg
     5521 aaccgacaag taacaagtac gaatgaatcg aacgaaacag tcaatatcaa tgcgatccaa
     5581 acagatgcag cgatcaaccc gggaaattct ggtggtcctt tagtgaatat cgaaggacaa
     5641 gttatcggta tcaactcaag taagatcgca agtacttctg aatcgacttc taatgtaagc
     5701 gtagaaggaa tgggatttgc catcccaagt aacgatgtag tgaatatcat caaccaactg
     5761 gaaaaagacg gaaaagtgac acgtccagct ctaggtatca caatggtcga cttatctgcc
     5821 gtttctactc agcaacaaga acaaatcttg aagattcctt catctgtaac taacggtgtc
     5881 atcgtgacaa atgtccaaac agctacaccg gcagaaaaag ctgggttgaa acaatacgac
     5941 gtcattacta agatcgatga caaagaagtt tcttctggtg tagaacttca atctgctttg
     6001 tataagaaaa aagtgggaga ttctgtcaaa atcacttact atgaaggctc gaaagaaaaa
     6061 acaactactg ttgaattgac gatcgatcaa tcggcattaa aacaaaatca aaatagtgaa
     6121 aattaataaa aaagaggttg tgacaaagac ttgtcacaac ctctttattt tggaaatact
     6181 tctccgacta cggcatcctc aggcaatact aagattcctt ttttttctgg agcatttggc
     6241 aaatgcaatt cacgagcaga acaaatcatt ccatagctgg ctacccctcg caaagttcct
     6301 ggccagatca tcattccatc tggcatcatg gctcctggtt ttgcaacgac aactttttgt
     6361 ccagcttcga tatttggtgc accgcaaaca atttgcaata ctgtcccatt gtccacttct
     6421 gtctcagtaa tcgataaatg gtcagagtca ggatgcggga cgcatgtttt tacatacccg
     6481 acaacgatct tcggttcatg atcagcttca agctgttctt cgaatcctgc ttctttaatc
     6541 aatcgattca atttcgctaa ttcttcatct gttaagctta cttggccgtt cccttcaatt
     6601 gttagatgat cggagatatg gaaaaagttc caagcaacaa cttgaccttg ttcatctttg
     6661 atccgagcaa cattccattt acgttcgaca gtgttttctg ttcctttatc gtcggctatg
     6721 ataaccatca aagtgtctcc gacgtgtgct ttgttataag caaaaatcat gttctttcct
     6781 ccattatcct ttgctgagat ttatcttaac aaaaaattgc attcactgca tgagattttt
     6841 ttcatgcttt atttccgaag aagcttcttc tggaacacca tttattcgta acaagggact
     6901 gtgacaagac ttttgtcaca gtccctttac tgtttgatta aaaaggttat acaagttcca
     6961 cttgcttaat tactcggctg ttcttcttcg tcagaaacga tcaagacatc acaaggtgaa
     7021 tgacgtatga cgtagctggc tacacttcct gtcataaagc gttcgactgc atttagtcca
     7081 gactgcccaa ccatgattag atcgattgca tatttttttg gcaatttgac tgccatggat
     7141 tcacgaacag agccgtatgc aataattcct tctatatttg tgtaatcaac agattttcca
     7201 tattctttac attcttcgat catttgcttg gctgtttcag tttgctgatc gactagattt
     7261 tgatcaatag gagcatagcc cataaaatta taaaattgct gatcgattac gtttgctaca
     7321 tatactttcc cattattacg gcgagccact tctaacgctt ttttgaaagc agcaagtgct
     7381 tgttcactac cgtcaatacc tactaaaatg ttcttatatt cttgattcat cttgacccct
     7441 cctaacagat gtcagccttt tattacactt tctaggaacg attcgatttc ctgttttgtt
     7501 ttacgatctt tattcactag acgacctaat tcttttccgt cttggatcac gacaaaactt
     7561 gggataccaa aaatgttcca ttcagcggct acatctatgt acttgtcacg gtctacttca
     7621 ataaattgcc aatcagaaaa gtcattttcg atttcaggca tttgcggttt gataaaacgg
     7681 cagtctccgc accagccggc agtaaagaaa aatacacttt ttccagtttc tacgtagcct
     7741 gctaattctt ctaaactatt tgggataatc attctttttc ctctactttc tgtttatgta
     7801 tttttcaatt aaattataca cctttctttc gaactaacaa acattgatcc tctttttata
     7861 aaaaaaatct gacaaaaggt tgcttttgcc agattttata gtttcactat cgcgttattt
     7921 cccgtatacg atcgtgttca ctgttgattt atctaaacct ttcaatgttt gaatcaacat
     7981 ttctcgtgca gcttcaaaat cgcgaatact gaacatcgtt tgatgcgtat ggatataacg
     8041 tcccactacg ccaatcactg tacttgggat tccttcattt tgtgtatgag cagcacctgc
     8101 atctgtaccg ccttttgaaa caaagtattg ataagggatg ttgtttgttt cagcgatatc
     8161 tagcaagtac tcacgcaaac gaggaagcat gatcaaacct ggatcttgga tacgcatcaa
     8221 tgtaccttct cctaaatgtc cgaatgtgcc atttttcgtc actgtgtcat ctgctgcaga
     8281 gcagtctact gcaaagaaca gatctggctt gaatttattg acagaagctt tagaaccacg
     8341 caagcctact tcttcttgga cattcgcgcc tgcaatcaat gtatgaccta atgtttcatt
     8401 ttgtaacgct tctaaagctt ctaataccat tgtacagcca tagcggttgt cccacgattt
     8461 gctgatgata ttcttcccgt tggctgtttt gatcgtttca gcgtaaggaa cgattgtgtc
     8521 tcctggaaga acaccgtaac tcattgcctc ttctcttgat tcaaacccag catcgaacaa
     8581 aatatctgtt acttctactg atttttgtcc gcttgttcct cgtaataaat gtgggggaac
     8641 ggaagaagaa atacatggat aattcttacc agtagaggtt ttaagtgtaa aacgttgagc
     8701 agaaacaacg taagggttcc atccgcctag aggtacgact ttaaaaagcc cgttttcttg
     8761 gatttgtgtc agcatgaatc cgacttcatc catatgtgct gcgaccatta cacgaggtgc
     8821 atccgcttct tcatggtggc gcagcccaaa aatgccgccc aaaccatcta actgtaactc
     8881 atctaccagc ggttccatat gactttccat ataggcgcga acgtcttgtt caaaaccgct
     8941 tgttccttgt aattctgtta actctttgat tcgttgaaat gttttttctt ccatatgcta
     9001 ttcgtctaaa tttcagacta aactcctctc agacttatat tgatctgcgg ataaaatatg
     9061 attttttctg cagaccgatc gtatttatta tagcttattt tttctggtag cggttattta
     9121 tttcaaagaa aatatgagag tgtggtaaaa taaacacaaa gagtagcaag tgagaagaag
     9181 gaggtatatc cacatgtatg aagaaagcga attaagctat tttaaaggcg ggttagccgt
     9241 tgggatcggt ctaggattat tgagtggggt agcttcaacg atttggtatc atcgcaaaaa
     9301 agtgttatca gcagaccaag tgcttgaaaa tatcaaaaca tcttttttaa aagaaggcgc
     9361 aatcgaaggt gcttggatct cttttgaaaa agaacctatt cggaaattcg ccgttcggtc
     9421 gagtgcttat cggggtgggc tttcccggat agaagatggc gaaactgttt attatgaatt
     9481 tttagcagat gctcatacag gaaccgtatt agacatttca agaaaaaagg gcgcaataga
     9541 ttaatacgtc aaaaaaatga aataacgaat acgcacccac tatctaaaag agaggtatcc
     9601 tatccttctt ttatagtggg tgatttttat aaaaataggg ctatttcctc ttggaatagc
     9661 tagtatttgt agttattata cggtattctt gaaataagat tagttttatt atataaggag
     9721 agtgacaaat ggaatcacgt gaaaaaattg ccgtgctcat tccttgttat aacgaagagg
     9781 cgacaatttc aactgttatt gaagatttta aaagggaatt accagaagca gatatttatg
     9841 tctatgataa taattcgacc gatcgaacat acgaattggc cgttcaaggc ggagcaatcg
     9901 taaagaaaga accacgtcaa ggaaaaggga atgtaatccg tcaaatgttt tttgatattg
     9961 atgccgatta ttatttgatg gtagatggtg atgatactta tcctgcagaa gctgcacatg
    10021 gtttgcttga gaaattacgt tctggcgaag cagatatggt cattggcgat cgtctatcaa
    10081 atggaaccta ttttgatgaa aataagcgtc ctttccatga ttttgggaat aatctggtta
    10141 aaaatacaat tacttactta tataaaacaa aaattcgcga tgtcatgacc ggctatcgag
    10201 gattcaatcg aatttttgtc aaaagcttcc ctattatgag ttctggtttt caaatcgaaa
    10261 cagaattgac gattcatgct ttagataaaa aattcaagtt cgttgagatt ccaatcgatt
    10321 atcgcgatcg tcctgaaggt agcgaatcaa aattgaatac attctctgac ggattcaaag
    10381 tgatcatgat gatcatcaaa atgtgcaaag attataaacc tttgcttttc tttgggatct
    10441 ggaccatctt cttcttttta tttggattgg tcatggggat tcctgtgatt cgtgaatata
    10501 tgctgacaag ctttattaca cgcatccctt ctgcgatttt aagtactgga ttgatgactt
    10561 tagcccttct ttcattagta acagggttga ttttggatac ggtcgtcaca aatgccaaga
    10621 aagaatatga attgaattta taccatgtct accacgaata tcaaaataaa gaaatgaagt
    10681 aggaggcctt ttttatgcat aagaaaaagg agaatctatt tcctactttt tttgcaactt
    10741 tatttgcgtc aggttttgct ttttttactt cttatggtct aggaactttg aatccaacag
    10801 taatcattgg tttagccatg gttttgctac ttgcttttaa gcaatatgga atagagttgt
    10861 tttcaataaa aaacaaagtt gcagctattg cccgattgtt tttttctgca gcttttgctc
    10921 ttacactttc tattggcaga cagatacaat ttcagtatgt ctcagcaaac tatacaaaga
    10981 caacgattgc tgatggaagt attttttact ttcttgttta tttctccatt tttgtgtatt
    11041 cttttttatt tttacaatcg atttatttat caatgccaaa actggaaaca ttttttactg
    11101 ctcaaaacac acaggctttc tcttcaagaa aatatttttt attctttact gtctttttag
    11161 ttctgtgttg gcttccttat ctgttggcat tgtatcctgg agtggttttg cctgattcgt
    11221 taagttcggt cgcccaatct atgggtgatg ttcctataag caatcatcat ccagtcttat
    11281 tcaccttact ggtcaagcta tttgttcatg atttaccaac tgatacgatc aatcacggtg
    11341 tatttttatt ttcgattttt caaacattga taacagcttc agcgataagt tattctcttt
    11401 gctggctgtt aaaaagaaac atccattttt ttccggtact cattagttta tgctattttg
    11461 catttgcacc ggtttttcca atctacgcct tgaacatgca aaaagatact ttgttctcta
    11521 tcgcttgctt tttattttcc ttagcggttt ttgactttat ttttcaacga gaaaagccaa
    11581 cgattctcaa tcagatttac gtaatcatcc ttgctttact gaccacctat ctaagaaata
    11641 atgggattta tgtagtaacc ggcacaggtt tgatttgcgg cttgattatt ttgaaacaaa
    11701 aaaggtatca agcattcttt caagtggtgc tgggttatac agtgattgct ggactactca
    11761 tccacccgtt gatggctcgt tatgctattc ctacagaaac tgctgaacaa ttaggtgttc
    11821 ctttgcagca aatttctaga actattgtta tggatggtga cttgtctaag aaagataaag
    11881 cattcatgaa tcagctactc ccgataaaag attatgaagc gtattctcct agtcttgcag
    11941 actcaatcaa gtggcataaa aattttaaca atgagttttt gaatacacat aaaaaagaat
    12001 ttctatcact atgggcaaga aatttaccaa gtaatataaa aatctataca gatgcttata
    12061 ttttagaaac gttcgggttc tgggtacctg gtacaaaaaa tagttacggc tttttagata
    12121 ctcgtgtaaa cacgaataat tatggtatga agcaagtaga tttgattgaa catcttactg
    12181 gattgtcagg aatgaaaaaa atcatcgatg ctcgtgattt ctttggttcc ggcacattac
    12241 tgtggttagc tatcggcagt gcacttttag caatctttaa gaaaaaatat cggtatttac
    12301 tcctttttct tcccggtatg cttgtttttg ctactattat gattgctact cctgtggctt
    12361 ttagtttacg gtatgtgttt gttttagcat taggtctacc tgtttatatc ctctctcctt
    12421 ttttactaga taaaagagaa aaaatgaaaa cagatatagg agatactcat gaaactattt
    12481 aaaaagatat tttttgcttt tgttctcttg atcgctagct attgcgtact actgacaatt
    12541 acttttttca ttccgcagca ctctattgaa tcgaatgcag aaaaatctct acagatggtt
    12601 gaaaaagaag gaatgtatcc ttctatcaat caaggaaata tgctaggcac tcggttagat
    12661 aattttactg atcatttgat gatacgaaaa acaaaagcag atcctgaatt gaactccttg
    12721 gagaacgcga tgtctatggc ggattatccc cgttattggc atggttatca gcttttttta
    12781 cgacctttac tgctagggat gagtttgggg agtattcgaa tgatttacgc agccattctt
    12841 tttctgctga ttggattgac gagctacttt ttaaccaagt gtagcgacat ctatttaacg
    12901 acagccttgt tgatttcgct tgctatagga aatgctgcaa cctttttctt cagtatgcaa
    12961 ttttcaaata tttggatttt gactttattg tctgtattac tatttttaac aaaaccacaa
    13021 ctctccaaca ccaaccaaca attattcttg tatttctttg tcattggttc tttagctaac
    13081 ttttttgact tgttgacaac accggtcatc tcttggggga tacctgtgat cattatttat
    13141 tatgtaacaa ataagtattt aatggataaa cgcagttcat tgagcaaaca agtaggcagt
    13201 tttgttttta ccggtatctt ttggggatta ggctatggtt tgacatgggt ggctaaatgg
    13261 atcctatcat cgatcatatt gaacaaaaac attgtaaaag atgcaatcaa ccaaatcctc
    13321 tttcgaacgg aaggaaacga caaatacccg ttgcatcgat tagagatgct gaaaagcaat
    13381 attagattga tgtatccaaa agtagcaata ttattgctat tgattacttg tcttgttttt
    13441 ctctattttg cttatcgtaa acgaaatagc tggcgtccgt tccaacttct agttttgttt
    13501 gttttagctg ctgtaacgcc gtatatttgg tacaatattt tagctaatca ctcacagatt
    13561 cattattggt ttacgtatcg tacgcaaatc atcacaagtt ttgctatact tagtgctttc
    13621 gcctttttga tccctcctga gaaatcaaaa gacgaactaa attactttta agaataccga
    13681 tgtactaatt catttttaaa cataaaaact ccagctgtca gagatagccg gagtt
//
LOCUS       DACDLM010000072        13508 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.074, whole genome shotgun sequence.
ACCESSION   DACDLM010000072 DACDLM010000000
VERSION     DACDLM010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13508
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.074"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..377
                     /locus_tag="IV356_002257"
     CDS             <1..377
                     /locus_tag="IV356_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAP9015917.1"
                     /translation="IEQPNLDRIKTARLEKKDKIVKNIASLDSDYFTELSNLYFSMTS
                     LLEVKLQEDDSDFLFLKSILEDSFEYTILFAKQKKFINKALNLNIDERKELESELFGN
                     LTQVQVNNLKREITARLISKLQ"
     gene            432..1598
                     /locus_tag="IV356_002258"
     CDS             432..1598
                     /locus_tag="IV356_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP9015918.1"
                     /translation="MSIQKYTTKSGARYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDTGYHKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFG
                     NKSISKITPVHCQNAVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPK
                     REKKENENYFSLEELKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFE
                     EQLMYVRKSYATIRNEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQA
                     RELLQFGINTNTKNQLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFR
                     HTHATLLLEGGASIKETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
     gene            2015..5242
                     /gene="fss3"
                     /locus_tag="IV356_002259"
     CDS             2015..5242
                     /gene="fss3"
                     /locus_tag="IV356_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HAP9015919.1"
                     /translation="MYKKQKKKLCVLTILSLAVQSIVGAIAPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCVEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIADYQKKPSFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENTANIDYRVN
                     GNQLIISPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTVKIDVE
                     MEGSLKIKKVDKESGDIIPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTATIKAGETISVTSKNTREKGQIILDKTGIETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGHETQGKAEFKRAEYTL
                     FTVKDGKAVKWTENFKPELLKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDSEKNAVITRDVAAKEQVIRFGFDFFKFAGSTTGTAETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDYTKSDYIFTITEKGQKQPIKTVTVPYGNLTNENFSVSLNR
                     LMLYDLPEEEDSLTSLATWKEGDKELTTLDSTELVDKLSYNLHEIKEDWYIVAQAIDV
                     DATKAAQEKDKKAKPVAIAETTATLANKEKTGTWEILHKLTVEQVLDKTIVLFNYVYE
                     SKEAYEAGDEPVAKDASLNNQAQTVNCMVERHVSIQTKAHLEEGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALFPDGTSKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYDKDGNINGKHNEDLKEKSQTLTPKKVPTTPSTPEQSEMPTVP
                     SGSQESSPTVKAFPQTGEKTSNVLLFIGFSLIFATAGYYFWNRRN"
     gene            5354..5668
                     /locus_tag="IV356_002260"
     CDS             5354..5668
                     /locus_tag="IV356_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAP9015920.1"
                     /translation="MELKFVVPDMVETFGKLTYGGEGEVLSEGYGRNTTIVGRSYHLF
                     SNKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLIAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            5681..6055
                     /locus_tag="IV356_002261"
     CDS             5681..6055
                     /locus_tag="IV356_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAP9015921.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQLNQGKPTNQNEGKK"
     gene            6065..6409
                     /locus_tag="IV356_002262"
     CDS             6065..6409
                     /locus_tag="IV356_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HAP9015922.1"
                     /translation="MEINVEHILDCLDQFGKGELTGEQLTNALTYDEKMFLIMHQGLL
                     EVGNDAKEDFDVLDWLGEEESFFMVVEVNESLCRQAESVLEEIDVEMPDAIERFLKQL
                     VETKQLPVVVND"
     gene            6478..7494
                     /locus_tag="IV356_002263"
     CDS             6478..7494
                     /locus_tag="IV356_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAP9015923.1"
                     /translation="MYKGHRIRAGDQHLIYHFVLGWLIFLFIGWMSVFYLQELRQFDI
                     SKVSFSTSEIGWSMKDVICLLGSLALSGSMMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQGEGFFKDLNSSWTKESISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LENKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIEEIVAENGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIQALLKSDAELFILDPKNADLADLGTIMPHVYSQK
                     EEISECVEDFYERMIARSRSMKEMPNYKTGENYAYLGLPPNFLIFDEYVAYMGANRFP
                     TSIE"
     gene            8088..9962
                     /gene="ltrA"
                     /locus_tag="IV356_002264"
     CDS             8088..9962
                     /gene="ltrA"
                     /locus_tag="IV356_002264"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAP9015924.1"
                     /translation="MNVETDEVQGSGKNVGKSVMEVPRLNTKIRYWEYYDLQETFDQL
                     FTQSRNGKKFYQLYELIISENNILLAYRTIKANKGSSTPGTDSFTIDNYKEMNQAEFI
                     HLILSHLENYKPKSIKRVMIPKPNGEKRPLGIPCMIDRMIQQMFKQILEPICEAKFYE
                     HSYGFRPLRSAKHALGRIMYLINISKMHYAVDIDIKGFFDNVNHRLLIKQLWNIGICD
                     KQVLAILSKSLKSPIQGEGIPSKGTIQGGIISPLLSNVVLNDLDHWVSKQWHTFETKY
                     PYTKGYNKFRALRDTNLKQGYIVRYADDFKIMTNDYPTALKWFHAVKLYLKDRLKLDI
                     SNEKSKIVNLRKCKSEFLGFAICVKQKGKKWVCNSRISNKKKDQIKEEIKQRIKDIQK
                     SPTAQNALLFNALVLGVHNYFRYATHINLDLNRMNYVLSFTTYNRLSNCSTRCYPNKA
                     SPTYKKFYSTTMKTYKVAGVYLYPLCDVSTKTIYGFNTEDTPFTPFGRQRLEHKSLQS
                     LVFQELRKLMESKIPNRTVEYLDSRISRYSMKSGKCEITKQFLPAKAVHCHHYLPKSL
                     GGDDKFDNLRIIHKDIHLLIHTTNKMIIDHYVHELKLVPEQIAKINLYRKMCNLQNIQ
                     "
     gene            10088..10444
                     /locus_tag="IV356_002265"
     CDS             10088..10444
                     /locus_tag="IV356_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HAP9015925.1"
                     /translation="MILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRV
                     ALGRMSELGYSMMFGEVDKNFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREIS
                     NIVGLTVHTERENNSV"
     gene            10489..11631
                     /gene="dcm"
                     /locus_tag="IV356_002266"
     CDS             10489..11631
                     /gene="dcm"
                     /locus_tag="IV356_002266"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HAP9015926.1"
                     /translation="MTFLDLFAGIGGFRLGMEQAGHQCIGFCEIDEFARRSYKAIHDT
                     RKEVEMHDITSVSDEFVRSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     ATLLQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQSRERI
                     FLIGHSRDACTEQVFPIIGSSSTSDQNIRNLVNINPSNRGMGGQVYGSDSVAPTLTGD
                     EGIKIALPVKDGISVAGMLSGNFEQGNRIYEVTGTAPTLSTKQGGTKIMIRKNETEYQ
                     EVKPGDSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKGVKAYDL"
     gene            11621..11910
                     /locus_tag="IV356_002267"
                     /pseudo
     CDS             11621..11910
                     /locus_tag="IV356_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395166.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            12166..13350
                     /locus_tag="IV356_002268"
     CDS             12166..13350
                     /locus_tag="IV356_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAP9015927.1"
                     /translation="MAQRNLDYRLLKERRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     IASTKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDVRKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYYAIQDLL
                     KGRSIESTTFSIINRYLRFADKVDGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     IV"
     gene            13365..13460
                     /locus_tag="IV356_002269"
     CDS             13365..13460
                     /locus_tag="IV356_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HAP9015928.1"
                     /translation="MEIVKDMLLVLGGSMLGVTVMCLMNASAAAD"
BASE COUNT         4611 a         2294 c         2883 g         3720 t
ORIGIN      
        1 ccatagaaca acctaatctt gatagaataa aaactgctcg tttagaaaaa aaggacaaaa
       61 tagtcaagaa tattgccagt cttgactcag attattttac tgaattatct aatctatact
      121 tttccatgac ttctttactt gaagtcaaac ttcaagaaga tgactccgac tttctttttt
      181 taaaaagtat tctagaggac tcctttgaat acacgattct atttgccaaa caaaagaagt
      241 ttattaataa agctttaaac ttaaatatcg atgaaagaaa agagttagaa tctgagttat
      301 ttggcaactt aacccaagta caggttaaca atctaaaaag agagataaca gctcgattaa
      361 tatcaaaact tcaataaaac taattattca atcagccaac tcgccaagtt atcagattgg
      421 agagattagt tatgtcaata caaaagtaca caacaaaaag cggtgcacga tatagtgtcc
      481 gcttgtatgt tcgtaaagat gaaaatggaa agcaagaata ctatgtaaaa aaagggttta
      541 aaactgaaaa agaagccaag ttacacgaag caagaaaaaa ggtcgagatt gaagataccg
      601 gctatcataa gccttctaat gacttgttta taacagtgta tgaagaatgg ttgccttctt
      661 ataggaatcg tgtacaagaa acgacatatc aacgtacaaa agaccttttc cgcttgcata
      721 tactaccaaa attcgggaat aagtccattt ctaagattac tcctgttcac tgtcagaatg
      781 cagtcaatga atgggcttta aaattcaaga atatcaaaca gcttaagtct tacagctctc
      841 aaatatttga gtatgccatt tttgcagagc tattacaccg aaatcctatg gcaaatacaa
      901 atctaccaaa gcgggaaaag aaagaaaatg aaaattactt ttcattagaa gaactaaaag
      961 ctttttggga tattctcaat aaagaagagc ctttaaaaca tattttaatc ttccagcttt
     1021 tgattactac tggtatacgt aaaggagagc tagctgctct tcattggtct gacatttatt
     1081 ttgaagaaca gctaatgtat gttagaaaga gctatgcaac tattcgaaat gaagagaaga
     1141 atgcaagaag aaaaactgtc aggattcaaa aaaatacaaa aaatatatct tccgaacgaa
     1201 tattaccaat tgatgcacaa actattgaaa tgttaaaaat ctggaaaaaa gaacaagctc
     1261 gagagctttt gcagtttggc ataaatacaa atacaaaaaa tcaacttatc tttacctatg
     1321 taaatgcaga cggtgacatt aatcaacctt tgcatgcgga ctattcaaat aatatattga
     1381 aacgtttaga gaagaaatat aaatttaagc acgttactat tcatggattc cggcacactc
     1441 acgctactct tctactagaa ggtggagcaa gtatcaaaga aacacaagat cgattgggtc
     1501 ataaaaatgc tgaaactacc cttaacactt attctcatgt tactgaaaaa gctcaacgaa
     1561 atgcgttaga aaaattcatt gcttacactg gtttataata ttgtcattac ctttctcatt
     1621 accagaacga aaaaaagaca ccttctcgca atgagaaagt gtctgaaatc gttggtataa
     1681 caacgattaa cgttttgaaa actgtgaagc tttacgtgct ttcttaagac ctggtttttt
     1741 cttcgtatca ttgaataagt ttgaaaagcc ttgatttata aaggtttttc cgtaaatata
     1801 ttttgttata tttgattaaa tttgaaatgt ttgtgttcta aaatgtgttc taatttaaag
     1861 gcagtatatt tcgtatttta tattaaattt ttaggctcat tcattctcaa atccattcta
     1921 tttagtcaat aaatatttta aaaagacttt ataaacaaag atgttcaagc gagcatctta
     1981 tttttttgtg cctaatttga aaggagaaca tttcatgtat aaaaaacaaa aaaagaaatt
     2041 atgtgtatta actattttga gtttggctgt tcaatcaatt gtaggagcaa ttgctcctac
     2101 gattgctttt gctgatgaaa ttacccatcc acaaacggta accgtagaac tagatttagc
     2161 acatcaatat gctgttgaag gaacttttag tgatggtcgt ccaatgtcag aagtcactgt
     2221 tccgcattat gcagtgtaca acggcgttaa acaagatatt ttctgtgttg aaccaggagt
     2281 cccgatttac aatgagttca ctcctggata tgagaagaac ccgttaccag atatgtccga
     2341 taaagccaaa ttagtttccg ttttatggaa aaaagtaggt acagatgcag atactcatat
     2401 tgtggcacag aagatgatct ggcaagaagt taatgggtat acccttcact caataaaacg
     2461 atcagatggt agtgccgtaa atatcgcagc cattgaggca aaaatcaatc aagccattgc
     2521 cgattatcag aagaaaccaa gcttccataa tagtacggct aaaacagtat tagggcaatc
     2581 gactactgtg acggatacga ataatctgaa tttgtcagag ttcgatgagg ttgtggaaaa
     2641 taccgcaaac attgattatc gtgtgaatgg caatcagttg ataatcagcc caaatgccaa
     2701 ttcaaaagaa agtggtgtgt tgacgcttaa gaaatctgct ggtaccggaa cacctgtcgc
     2761 ctataaaaag gctggccaac agactttaat ggccggggcg atcgataagc cgaacactta
     2821 tacggtcaaa attgatgtgg aaatggaggg ttctttgaag attaaaaaag ttgataaaga
     2881 atcgggtgat attataccag gaacggtttt ccatttagac tttggaaaaa ctttacccgc
     2941 aaaagacgtg accaccgata aagaaggcat tgcgacctta gatgagattc ctcatggtac
     3001 aaaggtaacc attactgaaa aatcggtgcc ggcgccttat acgattgata ccacacccat
     3061 gactgccaca attaaagcag gtgaaaccat ttcagtgact tcaaaaaata cgcgagaaaa
     3121 aggtcaaatt attctggata aaaccggaat tgaaacaggg agtgatcttt ggaacgataa
     3181 ttactcttta gcgggcaata cgtttgccat tcgcaaggat agcccaactg gtgaaatcgt
     3241 ccaagaaatg accacggatg aaaaaggtca tgcagaaaca ccaaaagaga ttgccaatgc
     3301 gttggaattg ggaacctact atgtgactga aaccaaggct agtcatggct ttgtgaatac
     3361 tttcaaacca gtaaaagtcg aattgaatta tgtcaatcaa acagtggctc ttgttaccag
     3421 taacgtaaaa gggcaaaacc aagaaattac tggtgaaacc actttgacaa aagaagacaa
     3481 agataccggt catgaaactc aagggaaagc tgagtttaaa agagctgaat acaccttgtt
     3541 tactgttaag gatggaaaag cggtcaaatg gaccgagaac tttaaaccag aattgttgaa
     3601 gggaacgaaa gcttctgatg aaaccgtaac tttgacttta gatgaaaaga atcaagttgc
     3661 cgttaaacac ttagcgatta atgagtatta ctggcaagaa accaaagcgc ctgaaggata
     3721 taccttggat gaaacaaagt atcctgtatc catcaaaaag gtggatgata gcgaaaaaaa
     3781 tgctgtgatt actcgagatg ttgcggcaaa agaacaagtg attcgctttg gctttgattt
     3841 ctttaaattt gctggatcaa ctactggcac tgccgaaact ggcttcaatg atctaacctt
     3901 taaagtgtcg ccattggaag gaaccaatga aatcaccggt gccgaagatg aagcgaccac
     3961 agcttataac gagcaattag ggtttgatgg ttatggcaag tttgaaaatc ttccttatgg
     4021 ggattattta cttgaagaag tagaagcccc agaaggtttt caaaagatta cgccattaga
     4081 aatccgttct acttttaaag aaaataaaga ggattatacc aagagtgatt atatctttac
     4141 tattaccgaa aaagggcaaa agcaaccgat taaaacggta acggtccctt atgggaatct
     4201 aaccaatgag aatttctcag tcagtttgaa ccgtttgatg ctttatgatt tgcctgagga
     4261 agaagatagc ttaacttctc ttgcgacttg gaaagaagga gataaagaat tgactactct
     4321 tgattctacc gagctagtcg ataaattgag ctataatcta catgaaatca aagaagactg
     4381 gtatatcgta gctcaagcca tcgatgtaga tgctacaaaa gctgcccaag aaaaagataa
     4441 aaaagccaaa ccggtggcga ttgcggaaac aaccgcaact ttagcgaata aagagaaaac
     4501 aggaacttgg gagattctgc ataaattaac tgtcgaacaa gttttagaca agaccattgt
     4561 cttattcaac tatgtgtatg aaagcaaaga agcctatgaa gctggtgatg agccggtagc
     4621 gaaggatgct agcttgaaca atcaagcgca aactgttaat tgtatggtgg aacgtcatgt
     4681 ttccatccaa accaaagcgc acttagaaga aggttctcag acctttactc atggtgacgt
     4741 ggtagatatg tttgatgatg tatccattac ccatgatgta ctagatggct caaaagaagc
     4801 ttttgaaaca attctgtacg ctttatttcc agatggtaca agtaaagaaa tttggaaatc
     4861 tggcaagatt gattacgaag tgaatgacaa agaatttacc aaaaccgtac ttgcggaaaa
     4921 agtggataca agtaaatatc cagaaggtac aagttttacc ttcaaagaaa ttaactatga
     4981 caaagatggg aatatcaatg gaaaacacaa tgaagatttg aaagaaaaat ctcaaacttt
     5041 aacgcccaaa aaagttccga caacaccaag tacaccagaa caatctgaaa tgccaactgt
     5101 tccaagtggc tctcaagaat ctagtcctac agtgaaggca ttccctcaaa ccggggagaa
     5161 aacttccaat gtgctactgt tcattggctt tagcttgatc tttgcgacgg ctggctatta
     5221 tttttggaat cgtcggaact aaggtgataa gatgaaacat gtaaatagta gaaaacaata
     5281 cgcgcgaccg cctcctaaaa aagtggtcgc gctatttttg tattcaaaac taacaatgaa
     5341 aagaggaaaa aatatggaat tgaaatttgt tgtaccagat atggtcgaga cgttcggaaa
     5401 actaacatac ggtggtgaag gtgaagttct atcggaaggg tatggtcgaa atactacaat
     5461 tgttggtcga agttaccatc tgttttcaaa taaacaacgg gccgatgata ttgaagtggt
     5521 ggtagctgcg gaagccggcg aaaaggattt tgaccaagat caaccactaa aagctgtaaa
     5581 tccccactta attgccaaag gctatgaaat tgagaatcgt gggtttaccg attacgtgtt
     5641 gtatgttgat gatttagtga aagcatagga ggaaaagaag atgagattaa cagaaggtat
     5701 tgtcgtagat tcaggattaa cctttggcaa gttgcgtttt tccgcattac gtcgagaagt
     5761 acgcaagcaa aatgaggacg gaacggttag taacgaggta aaagaacgga cctataattt
     5821 gaaatcctcc gcgcaaggtc gaatgatcca agtcagtatt ccagcaaatg tacccttacg
     5881 cgagtttgct tatgatgcag aggtagagct ggtcaatcca atcgtggata cggtcgccaa
     5941 ttatgttttt cgggaaggaa ccaccgttaa ttggtttatc aaggcagatg atttagtctt
     6001 gaaacgacaa ctgaatcaag gaaaacctac gaaccaaaat gaaggaaaga aataggtgaa
     6061 gaatatggaa attaatgttg aacatatttt agattgtctc gatcaatttg gcaaaggtga
     6121 gctaacgggg gaacaactca ctaacgcatt aacctatgat gaaaaaatgt ttctgattat
     6181 gcatcaaggg ttactggaag taggtaacga tgccaaagaa gactttgatg tactggattg
     6241 gttaggggaa gaagagtctt tctttatggt tgtcgaggta aatgaaagtt tatgtcggca
     6301 ggcagaatct gttttggaag aaatcgatgt ggagatgccg gatgccatcg aaagattttt
     6361 aaaacaatta gtggaaacga aacaacttcc cgtagtagta aatgactagc ataacttttt
     6421 gaaattgccc aatgaaatcc tattgggctt tttcgactgg aggtggaaac catcaaaatg
     6481 tacaaaggac atcgcatacg cgcaggagat caacacttga tttatcactt tgttcttggc
     6541 tggctaatct ttttgttcat tggttggatg agcgtctttt atttacaaga acttagacaa
     6601 tttgatattt ctaaggtatc attttccact agtgaaattg gctggtctat gaaggatgta
     6661 atctgcttgc taggaagtct cgctctttca ggaagcatga tgttacttta tatacacttt
     6721 tttcaggatc attggcgaag tctttggcat cgacaaaagt tagctcggat gattctagaa
     6781 aaccattggt atgaagtaaa gcagactcaa ggtgaaggtt ttttcaaaga tttgaatagt
     6841 agttggacca aagagagtat cagttacttc cccaaaattt attatcgaat gaaagatggc
     6901 ttactttcta ttcgcgttca aatttcactg ggaaaatatc aggatcagct attgaagttg
     6961 gaaaataagt tagaaagcgg actgtattgt gagttagtag aaaaagaact caaagactcc
     7021 tatgtggaat acaccttgtt atacgatatg attgccaatc gaattgggat agaagaaata
     7081 gtggcagaaa atggggcgtt gcgattgatg aaaaatcaag tatgggcgta tgattccttg
     7141 ccgcatatgt taattgctgg cggcacaggt ggtgggaaga cctatttctt actcaccatt
     7201 attcaagcac tattgaagtc agatgcagaa ttgtttatcc tcgatcccaa aaatgcggac
     7261 ctcgccgatt taggtacgat aatgcctcac gtatactccc aaaaagaaga aatttctgaa
     7321 tgtgtggaag atttttacga acgcatgata gctcgtagta ggtcaatgaa agaaatgccc
     7381 aactacaaaa caggagagaa ttatgcgtat ctcggacttc cgcccaactt tttaatcttt
     7441 gatgaatacg tggcttatat gggtgcgaat cgttttccta caagcatcga atagatgtga
     7501 aatggaagcc tattgagatt atcaatagtg acaactaatg ttttgagaga tggaatgaaa
     7561 gccttcaagt tgagctgaaa catccccgct aatactccta catgctctaa tcaatgaagt
     7621 agattggttt tggtatgaag ctaggtgaag tcgtctgaaa tctgcctaag tgcttgagca
     7681 taaggctgac tatagggcgg gcggctgaaa aagataacta tggtaagaat gtctgaaaat
     7741 gactgacgaa tctgcgaatg tacgggtcta aaaggctgat cttattgaaa gataggaaca
     7801 tacggacgta tggtgagata ccgacaagta aggttccatg atatgaaaat cgggatagct
     7861 aacgaagaag ctataatttc acaggctcat agtagatacc taaggttata catgatagct
     7921 aaaaacattg gaacgatgta agcagaaaac tatcaattaa atgactactt ctagataggt
     7981 gcatataagt aataacgaaa ttgctttgtt tctgtgaaag taagggcaca gtaccgatga
     8041 agcgtctaac aaatgtggag ggatagccct aagtctattt aataacaatg aatgttgaaa
     8101 cagatgaagt tcaaggatct ggtaagaacg tgggaaaatc cgttatggag gtgccacgct
     8161 tgaacacaaa aatacgttac tgggaatatt atgatctaca agaaacattc gatcagctat
     8221 ttactcaaag tagaaacggg aaaaagtttt atcaattata tgagttaatc atttctgaaa
     8281 ataatattct tttagcatac cgtactatca aggcaaacaa ggggtcttcg acaccaggaa
     8341 cggattcctt cacaattgat aactataagg aaatgaacca agcagagttt atccatctta
     8401 ttctcagtca tttagaaaat tacaaaccaa aatccataaa gcgagtaatg atacctaaac
     8461 ccaatggtga gaaacgccca ttaggaattc catgcatgat tgatcgaatg atccaacaga
     8521 tgttcaagca gatactggag ccaatatgtg aagctaagtt ttatgaacat agctacggtt
     8581 tcagaccatt gagaagtgca aagcatgctc taggtcgcat tatgtatctc ataaacatca
     8641 gtaaaatgca ctatgcagta gacattgata tcaaaggttt ctttgataat gtaaaccacc
     8701 gtttactgat aaaacaatta tggaatatag gaatttgtga caaacaagtc ttagctattc
     8761 tttcaaaatc tctgaaatca cccattcaag gagaaggtat cccgagcaaa ggaacgatcc
     8821 aaggaggtat catttctcca ctattatcta atgttgttct aaacgactta gaccattggg
     8881 tctcaaagca gtggcatacc tttgaaacaa agtatcccta tactaaaggt tacaataaat
     8941 ttcgtgctct aagagataca aatctaaagc aaggctatat tgtcaggtac gcagatgact
     9001 ttaaaatcat gactaatgat tatccgacag cattaaaatg gttccacgct gtcaagcttt
     9061 acctaaaaga cagacttaaa ttagatattt ccaatgagaa gtctaaaatc gtcaatttgc
     9121 gtaaatgtaa gtcggaattt ttaggattcg ctatttgcgt gaaacaaaaa gggaaaaaat
     9181 gggtttgtaa ttcacgtatt tctaacaaaa aaaaggatca gattaaagaa gagattaaac
     9241 aaagaatcaa agatattcaa aagagtccta cagcacaaaa tgctctcctg tttaatgctc
     9301 tcgtgctcgg tgttcataat tatttcaggt atgccactca tattaattta gatttgaata
     9361 ggatgaacta cgttctttca ttcactactt acaaccgatt atcaaattgt agtacaagat
     9421 gttaccccaa caaagcttcc ccaacttaca aaaagtttta ctcaacaacg atgaaaacgt
     9481 ataaagtagc tggagtctat ttgtaccctc tttgcgacgt atctacaaaa acaatttacg
     9541 gatttaatac ggaggataca ccgtttactc cgtttggtcg tcaaagattg gagcacaaaa
     9601 gcctacagtc tcttgtgttc caagaattaa gaaaattgat ggaatcgaaa ataccgaata
     9661 gaacggttga gtatttagat agtagaatat ctcgttactc aatgaaatca ggcaagtgtg
     9721 agattacaaa acaatttttg ccagcaaaag ccgttcactg tcatcactat ttgccaaaaa
     9781 gtcttggtgg agacgacaaa ttcgataact tgagaattat tcataaggat atccatcttc
     9841 tgatccatac aacaaataaa atgataatcg atcactacgt gcatgaactg aaactggtgc
     9901 cagagcaaat agcaaaaatc aacctttatc gaaagatgtg taatctgcaa aacattcaat
     9961 agaaaataaa tagatggaac gccgtatgag gtgaaagtct cacgtacggt gtggagcggg
    10021 ggaaaagatg gagattatat caaattctta cctatcgcta tagatgttaa cgacaaaaga
    10081 aagtgcggtg attttgaata agcttaaaca aatcgtgatg ttaggccgtc aatctggttt
    10141 ctttctgatt ctagcttgtc aaaggccgga tgcgaaatat ctaggagatg ggattcgcga
    10201 tcagtttaac ttccgtgtgg ctttgggtcg tatgagtgag cttgggtatt ccatgatgtt
    10261 tggagaagtc gataaaaatt tttttatgaa acgcatcaaa ggacgaggtt atgtagatac
    10321 agggggcagt gtgattagtg agttttatac gccacttgta ccaaaagggt atgatttctt
    10381 aagggaaatt agcaacattg ttggattaac cgttcatacg gaaagagaaa ataatagtgt
    10441 gtagcctagg aatatcaata atcctgggct tttttattga ggtgatttat gacattttta
    10501 gatttattcg ccgggattgg tggctttcgc ttaggtatgg aacaagccgg tcaccagtgt
    10561 atcggttttt gtgaaattga tgaatttgct cggaggagtt ataaagcaat ccatgataca
    10621 aggaaggagg tggaaatgca tgacatcaca agtgtatcag acgaatttgt tcgatccctc
    10681 ggaccagtgg acatcctttg cggcggcttt ccgtgccaag ctttttcaat tgcgggaaag
    10741 cggcaaggat tttccgatac tcgaggtact ttattctttg aaatcgctcg gttcgccact
    10801 cttctccaac ctaagtttct attccttgag aacgtccggg gattgctcaa tcacgaagga
    10861 ggggctacgt tcgagacgat cctccgaacg ttggatggat tggggtatga tgtggaatgg
    10921 caagtgctta actcaaaggc ctacgttccc caaagccgtg agcggatctt ccttatcgga
    10981 cattctcgag atgcatgtac cgaacaagta tttcctatca ttggatcgtc ttcaacatct
    11041 gatcaaaaca tcagaaactt ggtaaatatc aatccttcca atcgaggaat gggtggccaa
    11101 gtctatggtt cagatagcgt agcaccaacc ttgaccggtg atgaaggaat taaaattgcc
    11161 ttaccggtaa aggatgggat ttctgtagcg ggtatgttgt cgggaaattt tgaacaaggc
    11221 aataggattt atgaggtaac cggaacagcc cccactttgt caacgaaaca agggggaacg
    11281 aagattatga ttcggaaaaa tgaaacagaa tatcaagagg tgaagccagg ggacagtgtg
    11341 aacctggctt ttcctaattc cacaagtcgc cgaggtcgtc tgggaaaaca aagtgtgcat
    11401 accttactaa caggagacca acaagcggta gtcacggatc agtaccagat tcgaaagtta
    11461 acacctaggg agtgctggcg gcttcagggc tttccagatt gggcttttga tcgagcttct
    11521 caagtcaatt cagatagtca gttgtataaa caggccggaa actcagtaac agttccggtc
    11581 atttttgata ttgctagaag attaaagggg gtaaaagcat atgatttatg acgagttgat
    11641 tggagaaatc tactgggtga ttggcaagat tcaggcagat ccgaaattgg aagaagaact
    11701 gtaccggctc aattttgata ttcgcaaaaa cggggtgaaa gtccaggtga ttcgtatgta
    11761 gtggatgagg aaacggatgc tcgaatggag ctcaatcaag tcatcggtga attggaacga
    11821 attgcggacc ttgccaaaga acctgatatc cgccaatact tgtttgagat aaaagcagag
    11881 ttggaaattg agggtatcac cgcggagtaa tagggaaata acccactgat aggcactgac
    11941 cgcgggggat ttgcgaagca gaaatcctcc gtggtgctgt gcctgttcat ggacggcggc
    12001 agccggccat gatgtctcac cccccgtatc taacaggggg gtacaaaaac acaaaaaaca
    12061 agcaagtaac cataaaaaat gcttgttgta tcaaggatat taagtaattt gtataggtgt
    12121 taactcattt ggaaaagtta acaccttgaa tttggaggtg aaaacttggc gcaacgaaat
    12181 ttagattatc ggttattaaa agaacgacgc aacgaatatg gcgtttcaca aaataaatta
    12241 gctactgctt gcggacttag ccgcccatac ctaaatcaga tagaaaacgg tggcgtaatc
    12301 gcctctacaa agaccatgag aaaaattttt gatcaactgg aaagtttcaa tcccgattta
    12361 cctttaacgt tactatttga ctatgtaagg attcgctttc ccacaacgga tgtgcggaaa
    12421 attattcaag aaattctcca tttgaaattc gagtatatgc ttcatgaaga ttacgccttt
    12481 tactcctatc aagaacaata tgtcatgggc gatattgtag tgatgttatc tcatgaagaa
    12541 gataaaggtg tccttttgga attaaaaggt cgtggttgcc ggcagtttga aactttttta
    12601 ctcgcccaaa agcgtagctg gtacgacttt tttgaagatt gtctaaaagc cggtggcgtg
    12661 atgaaacgct tggatttagc aatcaatgat cgagtggggc tactggatat tcctgattta
    12721 acgaaaaaat gtcagaagga agaatgtatc tccttgtttc gtaccttcaa aagttaccgt
    12781 tccggggaac tgttgaaagc tgatgaaaag gatggtatgg gcaatacctt atatattggc
    12841 agcctcaaaa gcgaggttta tttttgtttg tacgaaaaag attatgaaca atatatcaag
    12901 ttagggattc cattggacca gaccgaaacg aaaaatcgtt ttgagattcg gttgaaaaat
    12961 gaccgtgctt attatgcgat tcaagatttg ttaaaaggtc gtagcattga aagtaccacg
    13021 ttttccatta tcaatcggta tttgcgattt gcggataaag tagatggaaa acggcgaacc
    13081 aattggccct tgaatgaaca atggggtcgt tttattggac ggaatcggaa agagattcaa
    13141 ttaacttctg aaccgaaacc gtataccatt gaacgaacat taaattggct aggtagacaa
    13201 gtcgccccta cgtggaaaat ggctaaggag ttggatcgat tgaatcaaac aacgtatatc
    13261 caggatatgg tacagaatgc gcgactctcg gaccggcata aaaagatttt ggagcaacaa
    13321 agtatggcaa tcgaaaactt gattgtatga aaagaggaat tttgatggaa attgtaaaag
    13381 atatgttatt ggtacttggt ggcagtatgc ttggtgttac cgtgatgtgc ttgatgaatg
    13441 caagtgcagc agcggattga gcaatggaaa agaaaggaaa gtgacaaaat gaatttcgga
    13501 caaaattt
//
LOCUS       DACDLM010000073        13489 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.075, whole genome shotgun sequence.
ACCESSION   DACDLM010000073 DACDLM010000000
VERSION     DACDLM010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13489
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.075"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(165..389)
                     /locus_tag="IV356_002270"
     CDS             complement(165..389)
                     /locus_tag="IV356_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HAP9015929.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(587..2167)
                     /locus_tag="IV356_002271"
     CDS             complement(587..2167)
                     /locus_tag="IV356_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HAP9015930.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(2568..3944)
                     /locus_tag="IV356_002272"
     CDS             complement(2568..3944)
                     /locus_tag="IV356_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAP9015931.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(4072..5190)
                     /locus_tag="IV356_002273"
     CDS             complement(4072..5190)
                     /locus_tag="IV356_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP9015932.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            5332..5766
                     /locus_tag="IV356_002274"
     CDS             5332..5766
                     /locus_tag="IV356_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP9015933.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(5844..6377)
                     /locus_tag="IV356_002275"
     CDS             complement(5844..6377)
                     /locus_tag="IV356_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HAP9015934.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(6471..7649)
                     /gene="mutY"
                     /locus_tag="IV356_002276"
     CDS             complement(6471..7649)
                     /gene="mutY"
                     /locus_tag="IV356_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HAP9015935.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(7642..8439)
                     /gene="recX"
                     /locus_tag="IV356_002277"
     CDS             complement(7642..8439)
                     /gene="recX"
                     /locus_tag="IV356_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HAP9015936.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            8546..9928
                     /gene="rlmD"
                     /locus_tag="IV356_002278"
     CDS             8546..9928
                     /gene="rlmD"
                     /locus_tag="IV356_002278"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAP9015937.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(10102..10680)
                     /locus_tag="IV356_002279"
     CDS             complement(10102..10680)
                     /locus_tag="IV356_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin-binding protein"
                     /protein_id="HAP9015938.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            11002..11472
                     /locus_tag="IV356_002280"
     CDS             11002..11472
                     /locus_tag="IV356_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HAP9015939.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(11580..12806)
                     /locus_tag="IV356_002281"
     CDS             complement(11580..12806)
                     /locus_tag="IV356_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HAP9015940.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
BASE COUNT         3960 a         2719 c         2248 g         4562 t
ORIGIN      
        1 gtaaagaaca cttttgtctc acgctctaaa cacgtataaa cggcgaaagc agaagcaact
       61 ccttcggaaa taagctgaaa ttcacgaaaa ttgcttttca aatttttgtg aattccagct
      121 tatttcttgg agttaaacgc ttctgtctca gcctcttttt ctttctagct ttttgatttt
      181 tctcttttct tttgtacttt tctcttttca ttttcagttc tacgcgtgtc tttattttta
      241 actttttcct ctttatggat gattgatcgt actttttgtg caatttgctc gtttttgtcc
      301 cagtctttta catctaataa tcgacataat cgtaacatct cttctttttt ctgttttttt
      361 ctttcacgtc tttgccattc tgtttccatg tgtcacactc tcctttcttt aatcatatgt
      421 acgcaaaata atttttatat ttttttgatt agacatttct atgattttaa tatagtaaaa
      481 agagccgtca cggaaaatcc gtcacggctc taaacaaaat atgagaggct gtttttgttt
      541 ggctattctt attacttgat gcagggcagc ttgtgtcaag acttctttac atcaaacttt
      601 ttaattttac attgggatat ttatccgcaa accagcgttc tgcaaattgg ttctcgaata
      661 agaacaacgg ttggtcgaaa cggtcacgag ccaagatatt gcgacttgaa ctcatcttct
      721 catccaaatc ttctggatcg atccagcgag cgattttgtg tcccattgga gacatgatta
      781 cttcggcgtt atactcattt aacatacgat attggaatac ttcgaattgt agctgaccaa
      841 cagctccaat gatatattct tccgttagat atgttttata aagctgaatc gctccttctt
      901 gaactaattg atagattcct ttgtggaagg atttttgttt catgacattt tttgcagtca
      961 ctttcataaa cagctctgga gtaaatgaag ggagttcttc ataagcaact tttagttttc
     1021 cttcgaacaa tgtatcccca atctgataat tgcctgtatc atatacaccg atgatatcgc
     1081 ctgctactgc tttttcgacg ttttctctcg aatctgccat aaattgtgtg acattgctta
     1141 atttcagttt tttatttgta cgttccaacc agacatccat tcctcgttcg aatgttccag
     1201 aacagattcg gacaaaagcg attcggtcac gatgggctgg attcatattt gcttggatct
     1261 tgaatacgaa acctgaaaat tcttcctcat aaggacttac catctgatca tcttgtgttt
     1321 tgtgtccata aggagctggt gccaattcaa cgaaagtctc taaaaaagtc tgtacaccga
     1381 agttagtcaa tgcagaacca aaaaatactg gtgtctgatc gccacgagca attttttctt
     1441 gattaaatgc atctccagcc tctttgatta gttctacttc ttctaagact tgttcatata
     1501 aggaattttc agttagagga tgattttcgg gaagcagtcc atcttcatcc aattctacta
     1561 atcgttcatc ctgataattt tccggacgat aaaactctac acgattatgg tagatatcat
     1621 aaagaccttc tagcccttta cccataccga ttggccaatt catcggataa gattcgatat
     1681 ctaatagctc ttctaattct tctaacaatt ccaatggttc acgaccatca cgatctagtt
     1741 tgttgataaa agtaaatatc gggatgccac gtttttttac aacttggaat aatttctttg
     1801 tctgtgcttc gatccctttt gcactatcga ttaccatgac cgcactatcc acggccatca
     1861 aagtacgata agtatcttca gaaaaatctt catgtcctgg tgtatccaag atatttactc
     1921 gtttcccttg ataatcaaac tgcataacag aactagtaac agaaatccca cgttgtttct
     1981 cgatttccat ccagtctgat ttggcaaaat tacctgtttt tttgcctttt acggtcccgg
     2041 cttgacggat agccccacca aacaatagta attgttctgt aatcgttgtt ttcccagcat
     2101 ccggatggga aatgatcgca aaagttctgc gattgtccac ttgttgcttt aattttggat
     2161 tattcataac ctaactccat ttcttccatt caattattta tattttctct aggcacagat
     2221 tgtccgatct cttaaagaaa gacaatttca tatagggctg tgacaaaagc cgtgtagcag
     2281 tctctttttc cgagtaaacg gcgttctaga gacagcctat cagcaataag cccacccaag
     2341 ccaaaaatac gaaaagctgt ttttgcttgg ctgctcttat tacttaatgc aggatagctt
     2401 tttcacaacc tttgtcaact actacaactg aatcagtata gcatggattc agcgaatgaa
     2461 aaagccacca aaccataaga gtcaaatatt tttttgtcag ctgactaaaa gaaaagacgt
     2521 gttgcttgtt tattcaagca acacgtcttt cataaccaag tttccaatta tcttcttggc
     2581 tcgtcatctt cgaattcttt tctgaagtat cttcgttctt cttcaggttc cgcttctgtt
     2641 tcttccggat catgaaaaat gacacggatt ttaaggattc gagaaccttc catttcttca
     2701 gaaaccagcg taatattatc gacatcaaac gataactttt cgccttcatc cggaatcatg
     2761 cctaatgctg taatcaaata accagccatc gtatctacat cactcatatg cagatcactg
     2821 tcaaaagctt cattgaactc atcaatcagc atacgtcctt ggatgatata ttcgtgttca
     2881 tcgatttttt cataaagatt ctcaacttca tctgattcat catcgatttc tccgacgatt
     2941 tcttctaaaa ggtcttctag tgttgctaac ccaacgacgc cgccatattc atctaataaa
     3001 atagccatct gattctgcgt ctttttcatt tcatataaca gatcatcaat aaagaccgtt
     3061 tcaggaacga ataaaggctc ctgcatgatt ttcttgatat ctaaattatc aaagccgaat
     3121 ttatgggcag cttttagtaa attctttgta tgaaggattc cgactacttt atctttgtct
     3181 tcgttataaa cagggattct tgaatagttt tcggataaaa cttcattcac attttcttcc
     3241 acagtgtcgt tgatatcaat cataaatgca tccgttcgtg ggaccatgac ttctcgggca
     3301 actttcgtat caagagaaaa aaccccttgg agcatttcta attcttcatt attcaatacg
     3361 ccttcgtttt caagcatata acgcatttca tctctggtca tttttgaatc ttcatcatca
     3421 aaagtcatcg gcgtgatacg cgccaataaa cttgtggaag cagaaagcag ccagacgaag
     3481 ggcttagcta ctacaccaat caagcgtatc agccctgaag tgaactttgc gacttcttct
     3541 gatttattta aagcaatacg tttagggtac aattctccaa aaacaatcga tacataggtc
     3601 aaaatagcca gcacaatgat atttgcaata ttttttgccg ctgtgccgcc acctaatacc
     3661 ggagctaacc gttccgataa agtattagct agtgaagcac cagacaaaat gttgaccaaa
     3721 gtgattccta cttggattgt cgataggaaa ttatttggat tctgcaatat ttttaaaagc
     3781 ttttgagatt tcacatctcc ttcatcagct ttttgctcga ttcgattctt attgatcgaa
     3841 acaacagcaa tttcggaagc tgctaaaaaa gcattgatca atgtcaaaac gatcaataat
     3901 aaaatctgcg ctaacagcga ctgactctca gggtcagcat tcataatcgc attctctcct
     3961 tataaaatta atttttagtt tacgatagaa aaaaacgtgg cactatagcc acgttaaaat
     4021 ggtatcacaa agcaattttc tttgcaataa aaacaagtgt actaaaacta cctacgaggt
     4081 cgtagcaatt ttcttcttgt tttcattttg cttgtcttct ttgacgattt tgattatata
     4141 ggaaatgatc gtcttgcaga ttgcgtaaaa aggaacacct aagaagatac caagcaatcc
     4201 ggcaatattt ccagctacta gaagaacgat aatgatcgtt aatggatgga ttttcagtga
     4261 tttcccaatt acattaggat aaatgatatt cccatccaac tgttggacga ttagcacaac
     4321 cacacaacaa agtaatgctt ttaccggatc attgaagact gttactagaa atgcaggtgc
     4381 tagtcctaga taaggtccta aatatggaat taggtttgtc aatcccgcaa tgaccccaaa
     4441 taagaaagca taatccacac caattaccat atatcctaaa aatgtgaagg taccaacgaa
     4501 taaacattcg attgcttgtc cgctaatgta attagccaat gttttattca gttgccccaa
     4561 taactccaca atttggtttc ttcttttttc tgggaaaaac tgttggatgt ttggcactag
     4621 tttttctccg tctttcaaca tatagaacaa gatgaatggt gctgtaatga ttactacggt
     4681 tgccgaagcg atcgttccaa cgatcgaacc taaactattg gatactccac taaggaattg
     4741 ctgaatgatt gtcccgtaag aaatgtctaa ttgctcaaaa tatttattga tatctacttc
     4801 cttgaacaaa ggcaattcgg ctacctcttt taaccagctt tctacctgtt tgatgaaatc
     4861 aggcatatta gatgccaatg aggaaatttg ctgtactaga cttgggatga cactaagtaa
     4921 aatccaaata attgctgcaa ctaaaaggag cagcacaatt gcgacagccc atattctttt
     4981 gatttttgct ttcatcaaca gcttgacaat aggattcaat aaatagtaaa gaaagcctgc
     5041 aatcagtaca ggtgcaaata acgtggaaaa aaatgtcccg atcggttcga aaataaagtt
     5101 tatttctgat gaaatcatga tcaatgcagc tatgatcaat aattcaagcg accaaaacat
     5161 tagtttagac tgtctaagtt tttcaaacaa tagatttcct cctttctttc ttactagtat
     5221 atattatatt cgttaaaaat tcttttattc tttttttatt tttgaaaact tgccatactt
     5281 tttatttgtt ttattttcca gtatactata cgaaaggaag gtggctagac catgaaagtt
     5341 gtacaaacaa aagatacaat gagcaatatt tacttagatg ctgtacggat caggcatcaa
     5401 gtttttgtag tcgaacaggg tgtgcctttg tctcgagaaa tagacaaaga tgaagcccat
     5461 tgtatccact tcgtcctgta ctcagataaa aaagaaccgc aaggaactgt acgtcttttg
     5521 cctttagaaa acggaaaaat gaaattacag cggatggcga ttctttctga atacagacac
     5581 caagggttag gaaaaatatt gattgaagaa gcagaaaact ttgctaagaa tcaaggctat
     5641 aatacgattt tattaggggc acagtccaca gctgaaactt tttacgaaaa actaggatat
     5701 acagcttacg gcgatccttt tgaagatgct ggcatgcctc atatttatat gaaaaagact
     5761 ttataaaaat ttatttcgaa aaaagcaaaa aacagcaagc ttttgagaaa aatctctcac
     5821 tggcttactg ttcttttttg tgtttactta cgcgacaatt gcttgtaacg gttataccaa
     5881 atatcaatat agccttccga gaacgggcca tctccattat tgatccagtc aaccagaatc
     5941 ttcacatttt cttttaggat gaagtcaata tcgttcgggt aattcatcat tttgctgtgc
     6001 atctcatatt catcgacatc caatagtcgt ttctcgccgt caggaaatac cttgatatcc
     6061 aagtcatagt cgatatattt caaggcctca tcgtccagca aaaaaggtga agctagatta
     6121 caataatagg aaaccccctt ttctctgatc attgctatta cattgaacca gtatttttta
     6181 tgaaaataaa caatcgctgg ttcgcgcgtt acccatcggc gtccatcaga ttcagtgact
     6241 aatgtgtgat cattcacgcc gatcatagag tgttcgcttg tttttaatac catggtatct
     6301 cgccacgttc gatgcaattt gccgtcgtgc ttgtaacttt ggatcgtcac aaactctcct
     6361 tcttttggaa ctcccatagc aacccttcct taagcagcat tttgtgcttt gtgtttgggt
     6421 gttcattaca ccgacatcat aattattata tcaataaaaa tgagctttgc ctagaaagga
     6481 ttcctattgt ttcgattttt ctctaactga tctaccagtt tcatttggac cttaggaaaa
     6541 acgaccgaat caaatgcatc aggcttcaac cacttcgaag ttttgttctc ggtaaattct
     6601 tgttctgctc cctcggttgc ccgtccgtaa aaaaggagaa catgccattt cagatgacta
     6661 aaaatatgag taacttctcc taaatgtcgt gtctgccaaa caaagagttc ctgcttttca
     6721 aatgggagat tttgctcttc ttctgctact aggtcatcaa acagatcgat ttctggcttt
     6781 gtttcccatt cttttttcaa tcgctcatac tcctcttgtg tcacttccat cattggaaat
     6841 gtccacatat tcgccagcaa tttttggcta tctctttctt caaaataata cgctccagaa
     6901 tgattttgaa gagctgcact gatataataa acgtcttttg gctttgcttt ttttgttttt
     6961 acaggaaaac tcgtttggat tcctcgtttg ttagctaaac aaaaggcttg gatcggacaa
     7021 gtctcacact ttggagaagt tggtgtacag atagctgaac ctagatccat cattgcttgg
     7081 ttgaattcac ctggatgctt ttcatcaatg attttccgca tcgcttcatc aaagattttc
     7141 ctgctagaag cttttgcgat gtctgcttca atgcaaaaca atctgctgac tactcgcatc
     7201 acgttgccgt caactgcagg ttctggaagt ccaaatgcga tacttgcaat cgcgcctgtc
     7261 gtatatggtc ctattccctt caatgagcta atttcttcag gcgtttgcgg catttcccca
     7321 tcaaattctg acatgatctg tttagcagca gcttggatgt tccgggctct tgagtaataa
     7381 ccaaggccct cccatgcttt taaaagcttt tcttctggag catttgctag ctcttcaatt
     7441 gtaggaaacc attccatgaa acgataaaaa taatcgatca ctgtgtctac tctggtttgc
     7501 tgaagcatga tctcagagat ccagatacga taaggatcac gattatagcg ccaaggcagg
     7561 tttctttttt cttgttcata ccattgaatg aactgatctt gaaattcttt tgtttcttta
     7621 tctgtccatt tttcccattc tttattcact ttcctcttcc ttttccgtaa tgaatcgctg
     7681 gatcatatcc aaatcaaatc ctttttgata taagctttgc tttactttta gatttctttt
     7741 tttaggttca aaccttaaat ttcttcgcca tagtttatct ccttgtttga ctaaataatc
     7801 atattctatt tcttgatctg cttcttgcgg aagatcagct atcgcttgtt ggatcacttc
     7861 ttgagaaaag cctttcgtca tcaatgtttg ttggattttt ctcaataatt ctttttggct
     7921 ttttccgtga ttttttccaa acgctttttc ggctgtctga tgtgcatttt gaacttggtc
     7981 ttcaaatgta tattggctga gcgcttgttc aatgatttca ggtttcaaac ctttttgctg
     8041 catctgctgc gctaatttct ttggtccttt gtcacttaag cgcatattcg tgcgcacata
     8101 actttcccca tagaccaaat catcgacaag gtccaattct tttaagcggg ctacgatttt
     8161 atttcgatct tcttgaagga tttccttttc ttttaagtat gttcggattt ctttttccga
     8221 tcgcaactga taacttaagt aattcattgc taggtgaaaa ccgaaatcag ctccgctact
     8281 cttcttgatc tcttggatag tttcttcgtc taattcccgt ccttttaata atcgatagcg
     8341 tactaataca tcttcagata cttgtaaagc ttctccttca gataaatcta cgcgatagaa
     8401 agggcctttg cctttactga ttctcgtaac ggttaacata aacatcctcc tcgaacatat
     8461 attctctatc ataccacaga aaatccccgt aatcaggtat tatatgttag aataaaccac
     8521 agaaaaaaga aaaagggaga tacttatggc agaaacaatt gtcaaaactg gacaaacggt
     8581 tcctttgaaa atcaagcgtt taggcataaa tggtgaagga atcggttatt tcaaacggtt
     8641 gatcatattt gttccatatg cactaccaaa agaagaagta ctagtgaaaa tcacgaaagc
     8701 aactcctcgc tatgcagaag gagaattaat aaaagtcaaa aaaacaagca aagatcgcgt
     8761 agtggcacca tgtcctgttt actatgaatg cggtggctgt caattacaac acttagctta
     8821 tcaagctcaa ttggatttta aaaaggatct gcttttgcaa gcattggaaa aattcaaacc
     8881 agcaggcttt cgatcttatc aacttttgcc gacgatcggg atggatgagc cttggcatta
     8941 tagaaacaaa gcacaatttc agttacgaaa aaataagcag actcaaaaaa ttgaagctgg
     9001 tttatacgaa gcaaactctc atcagttagt ccctataaca gactgcttgg ttcaagaacc
     9061 tcgaacacaa aaagtaatga atactgttgt tcaactattg aataaatttg atgcacccat
     9121 ctatgatgaa cggacaaaca gtggaatctt ccgcacaatc atggttagaa tcggtgttaa
     9181 aactggggag ttacaagttg tttttattac tcgcagtaaa aaattcccgc aaaaaaacgc
     9241 aatgatccgt gagatcaatg aacgactgcc cgaagttgtt tcaatcatgc aaaatgtcca
     9301 ggcacaaaaa acgtctctcg tgatggggga tgaaacgatc cacttatggg gaaaagaagc
     9361 cattgaagaa caaatcaatg aagtgacttt cgatctttct cctcgtgcct tctttcaact
     9421 caatcctcag cagaccgaat tgctttatgg cgaaggaatc aaagcattag atgtccagcc
     9481 taatgaaacg atcgtggatg cttattgcgg agttgggacg atcggcttaa gtgtagcaaa
     9541 acaagccaaa gaagtacggg gaatggatac cgttcctcaa gcaatcgctg atgcaaaaaa
     9601 aaatgcggaa agattaggat atcacaacac tcgatatgaa gtcgggacag cagagcaagt
     9661 tctgcctaaa tggttgaatg aaggttttca gcctgatggt atcatcgtag atccaccacg
     9721 tacgggtttg gataacgcat tgatccaatc attattgaaa taccctccaa aaaaacttgt
     9781 ttatatctcc tgtaatgttt ctacacttgc cagagatctg gttaatttaa gtaaaaagtt
     9841 caagattgaa tatttacagt ccgtcgacat gtttcctcag actgcacgtt gtgaagttgt
     9901 cgtgaagatg acgagactcg ctgactaaat gaaagaggtt gtgaaaaagt ctgccctgta
     9961 tcaagtaata agaacagcca aacaaaaata gctcttcatg ttttatgaat actgtacttg
    10021 tgaccgaaga gttaacagga ggacactatt tatttaaaaa aagggttgtg acatagtttt
    10081 tgtcacagcc ctttttgatt attattggat attcacgtct atcacttgat aaaatgcatt
    10141 tgtcgtatcg ctgatattcc atactgctaa aatcacatta tatccttttc gatcctgcgg
    10201 aagtgtgatc gtttggttga ctgtttttgg tggaacagtt gctttgtcgt ctatttttgt
    10261 gatcaattca aaatcactaa atttcaaagg ttgattagga ttccaagttg gtttggtaat
    10321 gtagtaatcc caagtacttg tccgatgttg tgctgttaaa ttccaagtaa tatttaatgt
    10381 tcctggatta accatgtttt tatgccatct gttagatgtc tgttcatcta aaggctcaaa
    10441 gccgctgact cctgcactag caatttttcc atcaatgaat gtatttttgg tagcttcgat
    10501 actttgcggt tcccattgtg ctcttccgac attttgattt aagtttcctg ctgctgatgt
    10561 tcctaggtat gcacggcttc ctggagaagt aatataacca tgcgcaaaac ctggaatgct
    10621 aaaaccgaac aaccctaaac taactaaccc aataaacaat aacgtactaa tctttttcat
    10681 gtagaaacct ccttcatttg ataaccacat tgtaaacgct ttattgtatt aacacaaaca
    10741 ttatgctttt ataattttat gttgaagtaa aaaaggtgaa aaaagtaaga tgcagattat
    10801 aacagaagta gacgagaaaa gtacaaatag aaaacatgag aatcaaatca tatgatcttt
    10861 ttcaaaaaca tcattcatat aaacaaatgt tcaacttttt aataacaaca attatcaatt
    10921 tttttcttac ttcacaaact aaatacaggt cttgctgtga gccttcatgg taaactaata
    10981 ttatagaaag gagttagtaa aatgaagatg ataaaagata ttcgtttttg ggtttgtgtt
    11041 ataggaattg tcatattagg ctttttatca gggttgctta gcggaaatcc cggaaaatat
    11101 tactattctt tgcaacttcc accatttgca ccacctagct ggatatttgg gccgatgtgg
    11161 accttactgt atatattgat gggtatttct ctttatttgt tacttaatca caacaacaaa
    11221 aaacagcgaa acaatcttgt cggtcttttt gtgattcagt tcatttttaa ttttatatgg
    11281 tctgctctat tttttaattt aagaaatatt ttcattgcag caatcgatat tacactttta
    11341 gttattttct tgtcagtgct tatgtatcag ttgtggctgc atcatcgcct ggcaatgtgg
    11401 ctcatgattc cttattattt atgggtacta ttcgcaactc tattgaatta ttcaatttat
    11461 tttttaaact aagcgctaaa aagagacgtc ctgtaattta acacatagaa aaagtgccac
    11521 ctaagttaga ttttttgtct aatttaggtg gcactcttta ttaaccaaac tatttttttc
    11581 tagtacccac ttgttgttcc atactcatta ttctggtcat aaccataacc attttgttcc
    11641 tgtccagcgt aaggatcata actttgagta tcttgacttg gtgtatagta ctgacttgta
    11701 tcttctgttt gctgataata ggtattcgga tcttggtact gatcatatgt gttttctgaa
    11761 taggaagaat aatcggtgta cccttcacta ttcgatccat caccgtttgt cgaatcgcca
    11821 tcttccgaat catcaaagaa catcattgaa gcattctcat ttttcaaatt aggtaatgta
    11881 tcgcttgttt ttatatttaa ttgtttcttc agttcatttt ggatcgaaag aagatcattt
    11941 tttcctaaaa tttgatagta gatatcattg atcatttgtc cttcgccttg caactggtct
    12001 tgtttgattg tttcaaacgc cggggtgtag ttcgtcgcta catcaagcat gtcatcccaa
    12061 tctaagtccg tcgtcacatt gttctcaact gcttttaaaa tttttctata attgcttacg
    12121 ccatctaaac ttaaaacttt attgacgatt ttcgtcacta cttcccgctg acgacgttgt
    12181 cgaccgatat cgccttctgg atcttcgtgt cgcattcgag aataggctaa acctttttct
    12241 ccattcaatg tttgttcacc tactggtaca tggacaccat ccaaagtaaa gtcaatttta
    12301 ttattcactt tgatgccacc gaccgcattg atcaaatctt ccatgccatc caaattgatc
    12361 gttacataat gatcaatagg aatatcgagc agttgctcaa ttgaatccat ggccatttcg
    12421 acaccaccaa atgcgtaggc atgatttaat ttatctaccg ttccataacc tacgatattc
    12481 gtataaatat ctcggtccaa actgatgatc gttgattttt tttgtttcgg attaactgtt
    12541 actaccatca tcgtatcaga acgtccttgt tccgttcttc ctaatccacc ggtatctaaa
    12601 cctaatagca aaaccgaaaa aggttctttg tcatcaatgc ttactctctc agaacgtttg
    12661 gaggatattc gattagagtt tttagaaatt ttgtttactg tttggctcgc ttctcccata
    12721 aatctgattc cgtatgctga taatccggca atcagcaaaa cgaatacccc taacaaggtt
    12781 aatagaactt tttgccatcg cttcataata cacctctgtt tcacattttc taaaatattg
    12841 tctcatataa ctgttcaatc agcaaattca ctttttaatc ataagaaaac tttaaaaaac
    12901 atttttgtgt aacgattatt attttttaaa atttctcaaa attcttaact atcataccat
    12961 accgtgaaaa agatcgaaag accgaataca cgcagttcgc aatcgtttta tcttttttta
    13021 tgtatttttt ccagaaaaag cgaacaacaa ggtattttcc aaataatcgt gcagtaaaat
    13081 gatcgcacat acctttccca tctttttaac agtctttgcc taccgttcag attatcattc
    13141 gatttcacga caatttcttc ctatgactgg tccttttgtt aaacccatct tctattcgtt
    13201 ttatttccag ctcactgcat ggctcttaaa atgactcgaa ctagtgattg cattaccatc
    13261 atcttttaat ggatagatat gctcctcttc aaagtaaaac gattttcttt taaagtaata
    13321 gaattgacat ggtaatgagt atgtatacta gtggtttcac aaatggtctt ttattcaaca
    13381 tccaaaaact gaaatttctt taaaatccat tactaacgaa gaaaatgttc cttgcttgat
    13441 aattagttag gacatgtcaa atgaacaaat gcatttactt agccaaaaa
//
LOCUS       DACDLM010000074        13462 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.076, whole genome shotgun sequence.
ACCESSION   DACDLM010000074 DACDLM010000000
VERSION     DACDLM010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.076"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..523
                     /locus_tag="IV356_002282"
     CDS             <1..523
                     /locus_tag="IV356_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAP9015941.1"
                     /translation="EKAIPYIAAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTIS
                     NEINQYREREPEIQPAEVKQEHKNTVETAENKNIVPVGSLWIDKKDGKVMEEDTGRTL
                     HLKDAAFIEDPQHNQVILKGKSYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNE
                     IYYEQQLSQKERV"
     gene            584..2053
                     /locus_tag="IV356_002283"
     CDS             584..2053
                     /locus_tag="IV356_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3991 domain-containing protein"
                     /protein_id="HAP9015942.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKHERQNF
                     LVGDDRLDHAVAFLWKDPQTGETVGASYQGTIVDFNRFGKRGTYKHIDKNPTPNHGFN
                     LKIGDPKHLKFFESSIDLLSYAALNREKLQDAWLVSMDGLKHHVISHYVEESISELRR
                     KQTFPQSIEICVDNDRAGHIFYEKEQMKGIVDPFTNKKIRCERGIPNDWQVPKEYKAT
                     YEAVAKEMSVEPEAIMAIHKTETNLQLTNQLVSAHDVQSTFGKMLAKGEPVETIDLKE
                     ACTTVAKELKVCERADGTYNFDRFYSRKANIKDVNAGILLSYKAEQYYKGYKKHEHEF
                     VPEVKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            2064..4073
                     /gene="topB"
                     /locus_tag="IV356_002284"
     CDS             2064..4073
                     /gene="topB"
                     /locus_tag="IV356_002284"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP9015943.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFTGETVIT
                     YGFGHLVELDSPDMYDEKWKQWALEHLPIFPNQYHYHVPKDKKKQFSVVKRQLQSADT
                     IVIATDSDREGELIAWSIIQQAGANQGKTFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEVQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEAYLKEKGVQLGKQPGTILQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIEKVPLDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKRSEGFI"
     gene            4419..5015
                     /locus_tag="IV356_002285"
     CDS             4419..5015
                     /locus_tag="IV356_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP9015944.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDPERTLCDIWNPWYTVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            5028..5927
                     /locus_tag="IV356_002286"
     CDS             5028..5927
                     /locus_tag="IV356_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HAP9015945.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNEIFSTPTKEGIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVI
                     HVEEKERKLAYQRHQQMNREMER"
     gene            5930..6061
                     /gene="ssb"
                     /locus_tag="IV356_002287"
     CDS             5930..6061
                     /gene="ssb"
                     /locus_tag="IV356_002287"
                     /inference="COORDINATES: protein motif:HMM:TIGR00621.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAP9015946.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGN"
     gene            6083..6415
                     /gene="ssb"
                     /locus_tag="IV356_002288"
     CDS             6083..6415
                     /gene="ssb"
                     /locus_tag="IV356_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAP9015947.1"
                     /translation="MIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEV
                     VADNFQLLESKAATESRAHADQSSTSPSTATFEQRNTATPNNNGLNASQNPFGGQSID
                     ISDDDLPF"
     gene            6437..6694
                     /locus_tag="IV356_002289"
     CDS             6437..6694
                     /locus_tag="IV356_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015948.1"
                     /translation="MAKKISLTMDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVF
                     VYLVCSYLLKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(6853..6975)
                     /locus_tag="IV356_002290"
     CDS             complement(6853..6975)
                     /locus_tag="IV356_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HAP9015949.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK"
     gene            7165..7389
                     /locus_tag="IV356_002291"
     CDS             7165..7389
                     /locus_tag="IV356_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015950.1"
                     /translation="MIKTQPLLVRFTLRTSHEPINCVVANIEIADKLLILEEGKYTIS
                     VTGHFNKRNQLVIESMQIRNPDHFTRLMGI"
     gene            7830..8036
                     /locus_tag="IV356_002292"
     CDS             7830..8036
                     /locus_tag="IV356_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HAP9015951.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            8036..8287
                     /locus_tag="IV356_002293"
     CDS             8036..8287
                     /locus_tag="IV356_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015952.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYEIEYWLTKLEN"
     gene            8302..8739
                     /locus_tag="IV356_002294"
     CDS             8302..8739
                     /locus_tag="IV356_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015953.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFAQIKKAKAMASDWLDTFESIEKNGAFYTIESEEKDNE"
     gene            8732..9439
                     /locus_tag="IV356_002295"
     CDS             8732..9439
                     /locus_tag="IV356_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015954.1"
                     /translation="MNKVVYQLTTEDVSQFLTSKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNHLDVYKRRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKGK"
     gene            9820..9999
                     /locus_tag="IV356_002296"
     CDS             9820..9999
                     /locus_tag="IV356_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015955.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            10340..10603
                     /locus_tag="IV356_002297"
     CDS             10340..10603
                     /locus_tag="IV356_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HAP9015956.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            10597..10947
                     /locus_tag="IV356_002298"
     CDS             10597..10947
                     /locus_tag="IV356_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAP9015957.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(10971..11585)
                     /locus_tag="IV356_002299"
     CDS             complement(10971..11585)
                     /locus_tag="IV356_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP9015958.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRL
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            11899..12321
                     /locus_tag="IV356_002300"
     CDS             11899..12321
                     /locus_tag="IV356_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015959.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            12331..12534
                     /locus_tag="IV356_002301"
     CDS             12331..12534
                     /locus_tag="IV356_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015960.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            12745..13329
                     /locus_tag="IV356_002302"
     CDS             12745..13329
                     /locus_tag="IV356_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP9015961.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT         4834 a         2209 c         2727 g         3692 t
ORIGIN      
        1 ggagaaagct attccttata ttgcagcatg gacgaagaat ggtcagacgt tggatgataa
       61 ggaagcggcg gaacgtggga aaatcatgaa tgatgtcagc cgtgtcgcaa atgaattcat
      121 tcaaaccatt tctaatgaaa tcaatcaata cagagaaaga gaaccagaga tccaaccagc
      181 agaagtgaag caggagcata aaaatactgt agaaacggca gagaataaga atattgtgcc
      241 cgttggttca ctttggatcg acaagaaaga cgggaaagta atggaagaag atacgggtcg
      301 aacgttacat ttgaaggatg cggcgtttat tgaagatccg cagcataatc aagtgatttt
      361 aaaaggaaaa agttatggaa aagagattca aacggcgtta ccttcagaag aatttgcgct
      421 aggaaatcca ttccgatttt cacttgaaac agtgtcagaa gtggccaaac gaaaaaatga
      481 aatctattat gaacaacaat tgtcacaaaa agaacgcgta taaaacaagt aaaaaagact
      541 atctgaaaaa cggatagtct tttttctttt gggaggtttg aaaatgaccg aaaaaaaaat
      601 gagtcttatt gatcgatgta aacagatcga tatagtggat tttgctcgaa acaatggaat
      661 ggctgtagtc aataaaggac gagactatcg cttagaagac catgattcat ttgtttttga
      721 tcgaagaaaa caacgttttt attggaacag tcaaaatatt agtggcgaca ttattgaatt
      781 agctaaactt tttttcatag acaaagagat ccaagactct aagcaacaat ttaaagcagc
      841 cactgatttt attctaaaga atgaagacaa aacagaacga gtggaaaatc ttcattttga
      901 aacagaaaag tacaaagatc accccgttga ttatcaacca ctcacagaaa aaggaaggaa
      961 ttatctgaag gaagaacgaa aactaccaga gtggctgatt gattatgcag aaaaagaagg
     1021 gttgattgct gaactaaagc cgaaacatga acggcaaaat tttttagttg gagacgaccg
     1081 tttagatcat gcggttgctt ttttatggaa agatccacag acaggagaga cagtaggggc
     1141 aagttatcaa ggaacgatcg tcgattttaa tcgtttcggt aaacggggaa cgtataaaca
     1201 cattgacaag aatcctacgc caaatcacgg atttaattta aaaataggcg atccgaagca
     1261 tttaaaattc tttgaaagta gtattgatct gttaagttac gctgcattga atcgggagaa
     1321 actacaagat gcctggttag tttcgatgga cgggttaaaa catcatgtaa tcagtcatta
     1381 cgttgaagag tcgatttctg aattaagacg aaaacaaaca tttcctcaat cgattgaaat
     1441 atgtgtggac aatgatcgtg caggacatat tttttatgaa aaagaacaga tgaagggaat
     1501 cgttgatcct tttaccaata agaaaatccg ttgtgagcga ggaattccaa atgattggca
     1561 agtacctaaa gaatacaaag ctacttatga agcagtcgca aaagaaatga gtgttgaacc
     1621 tgaagcaatt atggccatac acaaaactga aactaattta cagctgacaa atcaattggt
     1681 gtctgctcat gatgttcaat ctacgtttgg aaagatgttg gcgaagggcg aaccagtaga
     1741 aacaattgat ttgaaagaag catgtaccac ggtcgcgaag gaactgaaag tatgtgaacg
     1801 cgcagatgga acatacaact ttgatcgttt ttatagtaga aaagccaaca taaaagacgt
     1861 taatgcagga atccttcttt cctataaagc agaacaatac tacaaaggct ataaaaagca
     1921 tgaacatgaa tttgtacctg aagtgaaaaa ggattggaat gatcaattga agcatgagat
     1981 ccagcaacaa gaaatcagaa agcaaaaacg tgcgatgttg tttcaacaag gcagacaaca
     2041 agaaagggag tgaagtcgtc actatgaaaa ccgtcatttt agcagaaaaa ccgtcacaag
     2101 cgaaggctta tgccgatagc ttttctaaag ctacccgaaa agatgggtat tttgagatcc
     2161 aagatcgatt gtttacagga gaaactgtga tcacgtatgg ttttggtcat ttagtcgagt
     2221 tagattcgcc cgatatgtac gatgaaaaat ggaaacaatg ggcattagaa catttgccta
     2281 ttttccccaa tcaataccac tatcatgttc ctaaagataa gaaaaagcag tttagtgtcg
     2341 tcaaacgaca gctgcagtca gctgatacga ttgtgatcgc gactgatagc gatcgtgaag
     2401 gggagctgat tgcctggtca atcattcaac aagcaggcgc caatcaagga aaaaccttta
     2461 aaagactttg gatcaactcc ttagaaaaag aagccattta tcagggattc caacagttac
     2521 gagacgcaga agagacctat ccaaaatttg aagaagtaca agcacgtcag atcgccgatt
     2581 ggttaattgg gatgaacggt agcccactgt atagtttact cttgcagcaa aaaggcatac
     2641 caggaagttt ttctttaggt agagtccaaa ccccaacact ctatatgatt tatcaattgc
     2701 aggaaaagat tagaaacttc caaaaagaac catattttga aggaaaagcc caagtaatcg
     2761 ctcaaaatgg cgcatttgat gcgaagcttg atccaaatga aacccaagcg acacaagaag
     2821 catttgaagc ctatttaaaa gaaaaaggtg ttcaattagg aaaacagcca ggtacgatcc
     2881 ttcaagtcga aacagagaaa aaaagtgcgg ctagcccacg tcttttttct ttatcgagcc
     2941 ttcagtctaa aatgaatcaa ctcatgaaag ctagtgccaa agatactttg gaagccatgc
     3001 aagggttgta tgaaggaaaa tatctaagct atccgcgaac ggatacccct tatattacgg
     3061 aaggggaata tgcgtatctg ttggatcact tagacgaata caagcatttt ttaaaagccg
     3121 aagcgattcc gactcctatt catacaccga atagtcggta tgtgaataat aagaaagtcc
     3181 aggaacatta cgcgatcatt cctacaaaaa cggttatgac agcagcggct tttgaacaac
     3241 taagtccact gcagcaggct atttatgaac aagtgttaaa aacaacggtg gccatgtttg
     3301 cggaaaagta tacctatgaa gaaacaacga tcttgacgca agttcagcag cttcagttaa
     3361 aggcaatcga aaaggtgccg ctagatctag gttggaagaa gttatttgga aaagagagcg
     3421 acggaaaaga gaaggaagaa gagccgctac ttcctaaagt gacaaaagga gaaatggtga
     3481 cggtggatct acaagttctt gaaaaagaaa ccaagccacc acaaccttat accgaaggta
     3541 cgttgatcac tgcaatgaaa acagctggga aaaccgtgga tagtgaagaa gcgcaatcca
     3601 tattgaaaga agtggaagga atcggtacag aagcgacacg ggcgaatatt attgaaacct
     3661 tgaaacaaaa ggaatatatc aaggtagaga aaaataagct cgtggtgacg aataaaggga
     3721 ttttgctttg ccaagccgtg gaaaaagagc cgctgcttac gagcgccgaa atgaccgcca
     3781 aatgggaaag ctacttgtta aagatcggtg aacgaaaagg aacacaaacc acttttctag
     3841 ccaatatcca aaaatttgtc tctcacttat tggaagtcgt accagggcaa atccaatcca
     3901 ctgattttgg atcgacgtta caagaagtga aagcagccag tgaaaagcaa gaagccgcgc
     3961 gtcatttagg aatttgtcca aaatgccagg aacaagaagt cttactctat caaaaggtgg
     4021 cagcttgtac gtctgaagcc tgtgatttta aaaggtcaga agggttcatt tgaagcaacg
     4081 attgttttaa aagaagactt cactacaggc tttgaatttt ctgaaaagaa aaaaacgaac
     4141 ttcaagaaaa gaacacgccg cactgcaaaa taatggaggg ttaatcttat gcgtaatacc
     4201 acacacaaac aacaagaaat cgaaaatcaa aaagccaaaa ttcgttcaga acaggaaaaa
     4261 atgcgtgcca gcaaacgaag actgcagcaa ttgaagaacc agcagaggat tcaaaaagaa
     4321 atcgaattag atcgataaaa tcttcctaac tattgtatac gtataaactt atgttatact
     4381 gtttttataa gtttatacgt atacaaagga gggagaaaat gacaaaagca atggtataca
     4441 agctgctaga agaatttaat ggaactttgg ctttgaagga tgccaaaaaa gcgggcattt
     4501 ctcctgtaac gatcaaacgt atggtagatc gaggggagct ggatcgagag tatccaggtt
     4561 ttttcacctt acctggtcaa tttcctgatg aattgtttat ggcgcaaaaa aaatatgaac
     4621 gcggcattat ttcacatatt accgcgttag atttgtatga tttaacagat atgatcccta
     4681 gacagatcga tctgactgta ccttacggtt atcacgtttc tgaaaaagga ttgaaggaat
     4741 tcgcagttga gctacactat acaaaagcgg aatggtatga attaggtaag attgaaataa
     4801 aaagtcgcta tgggaatcct attatagctt atgatccaga aagaacttta tgtgacattt
     4861 ggaatccctg gtataccgtt gaggatgaaa tcaaagtaaa agcaatcaaa aactatatgg
     4921 agtcggacag aaaaaatctt agaaaattga atgagtatcg acgaatttta ccaacagaca
     4981 aaacgatgcg ttcttatatt atggctttaa attaaaggag aagatacatg acacctacgc
     5041 agttaaaagc aaaagtgaag aatatttcta gagaaaaaga agttgatccg cagcttgttt
     5101 taagacattt tatgatggaa aaattcttgg aaaaaatctc agagtctcct tatcgtgaaa
     5161 attttgtgtt aaaaggcggc ttcttgattg gctcaaagta tggcattgaa aatcgcacaa
     5221 ccaaagatat tgatacgact ttacgggaaa tgaaagtaac caaagaaaca ttaacaacgg
     5281 ttctaaacga aattttttca acgccgacga aagaaggcat tcaatttgag attcaaggaa
     5341 tgaaagaaac gagagaagcc gattactatc caggatttag cttacgtgtg ctggcacatt
     5401 tggaaaacat gcggccagat tttaaggtag atgtgactac aggtgactcg atctatcctg
     5461 caacgatcac tcacagtcat aaattgatgt ttgaggatcg aacgattcct ttggaatcct
     5521 atcctacaga acaaattatt gctgaaaaat taagtgcaac ctttgatttt ttaacagata
     5581 attcgagagg aaaagatttt tatgatctct atactattcc taaaatggag aagatcgatg
     5641 agaagacctt gaaagatagt gtgagaaata catttacacg tcgaggaaaa actgatccgt
     5701 taaagatata ctatgaaaag gatatggatg tactgaaaaa tagtcacgag ctaaaagata
     5761 cctggaagaa atatcaaaaa agcaatcctt atgctgcgtc gatcacgtac gatgagacaa
     5821 tggattcgat tagtaatttg atggaaaaag tgattcacgt cgaagaaaaa gagcgaaaac
     5881 tagcttatca aagacaccaa cagatgaata gagaaatgga gagataaaga tgattaataa
     5941 tgtgacatta gtaggacgct taaccaaaga tcctgattta cgttataccg caagtggtac
     6001 tgcagtagcg acttttaccc tagccgtcaa ccgaaatttc acgaatcaaa acggcaattg
     6061 agaagccgat tttattaact gcgtgatttg gcgcaaacca gcagaaacaa tggcgacatt
     6121 agctaaaaaa ggtagcttga ttggtgtagt tgggcggatt caaacgcgga cttacgacaa
     6181 ccagcaagga caacgtgtat atgtgactga agttgtagca gataactttc aactattaga
     6241 aagtaaagca gcgacagaga gccgtgcgca cgctgatcaa tcgtccacca gtccaagcac
     6301 cgccaccttt gaacaacgga atacagcgac gcctaacaac aatggattga acgcttcaca
     6361 gaatccattt ggtggacaat caatcgatat tagcgatgat gatctaccgt tttagtttga
     6421 gaaagaagga gtaagcatgg caaaaaaaat tagtctgacg atggatctat tgatacccgt
     6481 aattgcattt atagacggga tttctttggg cgtcactgaa aatcctttgg taaatagaat
     6541 tgcgaaagga tcactatttc ttgtattcgt gtatcttgtc tgttcttatc ttttaaaaag
     6601 agcaggaaag gataattcct tttggcgatt gactaaagtc acagtagcag cgacagctgt
     6661 tatacttacg gctattctac cgctttatat gtagagttaa cgggaaatcg ttgaacttct
     6721 tgcgaaatat tgctataatg aacatgaaaa agaggagttg cgctaacaac ccctcattaa
     6781 cagcaccgat taaagaacgg tggcagaata ttagttattt ggaaataacc gctgacctgc
     6841 taaagtagac ggttatttct ttttgtcatt tttaagcata tttacaatca aactaatcaa
     6901 agcaatggta aacataccaa aaccaagaat ggtttgaatt gtctcatatg cggacaaaag
     6961 gcttactcct ttcatagatt ttagcactta cattcataag caccaccacc tttccagaag
     7021 tcgccaccgt cttcaaactt tactgtcttg actattatag catatctaaa atcgaataaa
     7081 aattctcaat tttagctgtt tttgctataa ttttagcgag gtgatcgtga tggaacaata
     7141 tattggttta ctcgataaat tagggtgatc aagacacagc cattgcttgt gcgatttaca
     7201 ttacgcacga gtcatgaacc aatcaattgt gtagtggcca atatagaaat agcggataaa
     7261 ttgctgattt tggaagaagg caagtatact atttcagtga caggtcactt caataaacga
     7321 aatcaactag tcattgaatc aatgcaaatt agaaaccctg atcattttac gagattaatg
     7381 ggcatataaa taaaagaaga gctgcagtcc taaatgagga ttgcagctct ttttgtttta
     7441 catagaaaca ggaaaagacc tttttaggaa gacacaagtg ccttctcaat tgaaaaacct
     7501 ttctctcact ccaaccgcca ccgccgttcg agaagaaagg aagtgaacgc tgcacgttca
     7561 ctaagatatg gtgtcttgca aagcaagaca aaatagacaa aacttcctct caccaaaagg
     7621 ttcgttcctg ttcgttatct ctttattgat ttgccagacc ggcaacaagt tgccttttat
     7681 caccaaaaag cgacaaggac aagggtaaat ggcacgctgc gcgcccttgt ccttgtcgct
     7741 tttcgttgat ttattctggc caacaaatca ataaagaaag aactaacgaa aggaagtaaa
     7801 acctttccta agaggaggca gaatcaaaca tgcgaaagaa atttgattat tggggtgttc
     7861 ccttcagcga attattccca aactatcatg caccacatac tgttgaatgc gattgtggag
     7921 aaagagcgaa atgtatcaaa agctatcgtt tgtatcaatg tccaacatgc gggaaaaaat
     7981 ataccttgtc ttatggcgat tacattttga ttgatgagaa aggaaagaaa cgctgatgaa
     8041 aacacaacac aaattattga ctgtaaaaga agtcgttcaa attttggtgg acaaagaagt
     8101 catttctgaa aaagtagcag aagctttact tattccgcgg tactggacga tagaaacccc
     8161 tttagtagag gatgcaccga ctatgctatt tgaagaccta gtgaagattg caggatatga
     8221 actgcattat caagaaaaca tggaaactta tgaaatcgaa tattggttaa ccaaattaga
     8281 gaactaaaaa ggagaaaaaa tatggctcaa aattactatg acgaatttgt caaattacct
     8341 ttggataaaa tggcacaaaa aatggaggat atgacgttcc tataccatga aacacgtgta
     8401 cccaaaaaac attacaagga aaaattgtca gtcgcagtgg aagaaatgat tgaatcaggt
     8461 gtcgaaatga atctcattgc gacgtactat cgaacactgg aagaactgaa aaaacaaaat
     8521 ggaaaatggt ttttccaagc cttactatgc ttggaagtag gtgtcaaacc aagcactatc
     8581 aaaccttccg aatatcaagc cttagaactg acttatgcaa aattcgcaca gattaagaaa
     8641 gctaaagcaa tggctagcga ctggctagat acttttgaaa gtatcgaaaa aaatggtgca
     8701 ttttatacga ttgaatcgga ggagaaagat aatgaataag gtggtttatc agctaacaac
     8761 agaagatgtt tcgcaatttt taacaagcaa agaacacttg aatgaagtaa tcagacggat
     8821 tcaaaaagac tttagttgta tggaagaaat gaagtacttt attcaaagag tggaagaaca
     8881 gttgtatatg gaaagcgaaa caagtcaaac gaaggtcaca gtcagccata atcatttaga
     8941 cgtgtataaa cgtcgtcctg aaacggtaaa aaaaggaaca gagcttctac gactagaaac
     9001 agaaaaatac atcatgaatg tgtacctaga aaggagtgag ctggtcgaaa actttgtcag
     9061 ctacacgatt tgtaggaaac actattactc agaatcagaa tattattcaa ttttcgagag
     9121 catggaatta atggaagaag aaatggaaga gctaaacagc aaaaatgcga cggtagacga
     9181 ttattacctt gtatttacta ggtttttgac gtgtgggacg gaatctatcg tgttaatggg
     9241 aatggattat gaactcgctg tacccgaagc atttttgagg gaatatgtag aagaagtaga
     9301 taacccaggc gacgactggt acacgacttt aactgatttt ttagacacct acacttacga
     9361 cgatacagaa gaaatccaaa atgaacttga ccgtaaacga atgccatatc aacgatttga
     9421 aaggaaaaaa ggtaaataac catttatacc gaaaagtgag gatgtgtgaa ataagaacaa
     9481 aaaaccttga aattaaggga atggttctta tttcgcacca atcgctccaa ccgcccccgc
     9541 cgcttaggtg gtgcgaaata agcgggcaaa gcccgataac ctaagagaaa gaaggagatc
     9601 catatgaata aaatcattcc tctattgttc gtactgtttg ttggcgagat acttatgcgt
     9661 catgctgcag ctgtacattt aaacttcgta gtattcttag gaatactggt attttgtttg
     9721 atcttttggc gatttgtatt agcccttgtg agtctactat tcaagatgat tgcagccata
     9781 tttttcatag ggttatttcg atgaaaggag agagtactaa tgccaattgc aataggaaat
     9841 aaacggttac ccgtgacatt agatgaaaag agacaaaaag aattgcagca actaaagcag
     9901 aagtacggaa aaagtgaatc taagattatg tgtattgcgt tagatctatt gatcgcgcaa
     9961 gaaaaagcag gatttgatat accagcacta aaaaagtgac gtcacttttc atttgaagaa
    10021 acaaaagtga tagcacttaa ttgttcctac tatttagaat attttctatg tcctttttat
    10081 tccattttgt atcaataact atgaaatctt taaagtatcc agaagagatt atttttagat
    10141 caattttttt cttacctgat tctaaagatt ttgttttctt aaacatatta tgatttcctt
    10201 tcgactattt tcatataaat gttaacatag tttatggatt catggaatgt taatctaatt
    10261 taatagaaaa ggataattaa gtatatacgt tttttcttat gtatgttata ctatgtatat
    10321 acagaaagag gtgtctacta tggaaatgtt acctataaaa aaatggggaa atagtaatgg
    10381 ccttagattg ccaaagtata ttatggaata tcttggaatt catacagaag acaaagtgaa
    10441 gataatacaa gaagaagtaa acggtcagaa gcggctaatt atcgaagcgg ctaatataga
    10501 aaatgaatta acaattgaac agttatttga aaattacact gatgaaagaa atcatgtgac
    10561 gattcaaaat ttaggtgaag cagtaggtaa tgaaaaatgg tgagaaaacc tagacaaggc
    10621 gatattctat tattgaatac agcacctcga tctggacacg aacagacagg taaaagacct
    10681 tatattgttt taagtcatga tattattgcg gattatagta acgttgttac agttgctcca
    10741 atttctagta caactagaaa ctatccgcta tatgtaaata taaactcaga atatgaaatg
    10801 aagacaacag gaaaagtatt attagatcaa ctaacgacaa ttgattatga agccagagag
    10861 tgtatttttt tggaaaaagc gcatgatagt ttagttgagg agttattgat gaaagttaga
    10921 acagtttttc aaaaagtaag caaataaaat agaaacagca gcatgatcaa ctattcgtga
    10981 ttgaccatgc tgtctttttt tattctatat acggtttgtc tcgtaacatt gtagtctttt
    11041 gcaatcttag cgatcgcaac accttttttt agatcctcaa cgatgttttt ataaacaaga
    11101 cgacgttggg gatcttttgc attggcactg tatagcttag gacgtccttt ataaacaccg
    11161 ttcgcttttg caatcttaat gccttgtgcc tgacgtcgtt tagattcggt acgttcttgt
    11221 tcagcgatca tggccaaaat ttgaatgatc aaatctttaa tgaatttatc caggagagga
    11281 ttgccaattg cttcggccat gatcggtaga cttgtgatga tcagctgcac atttttcttc
    11341 ttcaagtaat tgactgaagc gatgatctcg tcgtaatttc ttccaagtcg atcaatagct
    11401 tccacaataa aaatatcttg atctcggacg aaatccagtg cttcttgaaa aacaagtcga
    11461 tgagtaatcg ttgcgccaga ttgtttctca atgaaaattc tctctgcacc gaattttttc
    11521 atttcttcaa tctgccgttg ttcattttga tcgatggatg agacacgtat gtatgcaact
    11581 ctcaaaattt ttacctactt tctgcaacta tttaaaaaac accctaatca tacacgagaa
    11641 aaccagattt ttcaatgtcg cggtcgtgtc tagttagggt ataccttata tagacaaaaa
    11701 ctaatgatgg aggaaatagt atgtgtcact tttcttttta aatggcaata ttttttgtaa
    11761 ataaatgtca atcaagaaaa tttaaacgat tatgacatta aaaatatatt ttatgaattt
    11821 tctagtatat aacttgattt atctgttaag atttattaag aaaacgtttt cttatttttg
    11881 atttcgaggt gatagacaat gaaaaataag tttattttat ctttaggtat tttaactatt
    11941 ggaattagtg taactggaac tacaattcct acatttgctg atagtacaaa tgaaccaact
    12001 actgtagtag ataataacca agaattaact cctttagata ggaacggaat agccattggt
    12061 aacccaacta acgacttaac tgttactgaa aattatttaa tagtttctcc attacttgct
    12121 cgagcagctt ctaaaacgat acgagtgaca ggaacgatga tttttgataa agttggttgg
    12181 ccttctagac ctcctcaatc acggaattgg aaagaaaaaa gaaatggtta ttggtactat
    12241 ggaaaattgt atttacaaag ttataaatca gctggaaaca attggattgc gacttattca
    12301 ggaaccttaa ctagaaagta gggatttttt atgccagaat ttgtgaacac accaaatttt
    12361 tatcaagata gcgatattct aagtaaaatt aatttaccga aagaagaatc agctttacaa
    12421 gttcagcgaa ctttacagga gacacaaaaa attcaaaaat caatttctaa tctagaagat
    12481 tctgaagaaa aaagaaaaaa aagagaccaa aaaacatatc aaaaagaaaa ataatgattt
    12541 taaaaaaaga gtgtctagtc gacattcttt ttttctaatt gaaagtgttc ataaaatcac
    12601 ccatttctgg acacttcctt tttttgcttt atttttcaaa aaaacaattc atttcatgtt
    12661 cataaaccca taacaatatc tatgttcagt taaactatat ggataaagtt atgttacaat
    12721 aaaattaatg aaggagtgat ttttttgaaa ataggatacg cccgggtatc tactggttta
    12781 caaaatttgg atttacaaga agacagccta aataaatttg gttgtgaaaa aatttttact
    12841 gatcatatga gtggggcaaa aagtaatcga ccaggattag aaatggccat tgattttgtt
    12901 cgctctggcg atacacttgt cgtttggcgc ttagatcgtt taggtagaaa tatggaagat
    12961 ttgatttcaa tcgtcaatcg actgaatgag cgtggtgtga gttttcatag tattcaagaa
    13021 aatattacga tggacaaatc aagttctaca ggacagctca tgtttcattt gtttgcggca
    13081 tttgcagaat ttgagcgtaa tttgatcctg gaacgatccg cagcaggacg agcagctgct
    13141 cgtgcaagag gacggtttgg tggtcgtcct gaaaaattgt ctgaacaaga tttggaatta
    13201 ctgaagactt tagtggatag cggtacacct attaagacta ttgcggaacg gtggaacgtc
    13261 tcaagaacca ccatttatcg ttatttggca aaaatggagg agaaaaatgg aaagacaaat
    13321 tctcattagt ttttgtcatt taatgctgaa aatttttgcc atttatctag aaaagtgaca
    13381 atagtatgag aattttttgt aagtgtctac tgataactta ttctcaaatg ttgtaaggat
    13441 tttattcatt tgttaatatt aa
//
LOCUS       DACDLM010000075        13146 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.077, whole genome shotgun sequence.
ACCESSION   DACDLM010000075 DACDLM010000000
VERSION     DACDLM010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13146
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.077"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(77..149)
                     /locus_tag="IV356_002303"
     tRNA            complement(77..149)
                     /locus_tag="IV356_002303"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Lys,seq:ctt)
     gene            530..1099
                     /locus_tag="IV356_002304"
     CDS             530..1099
                     /locus_tag="IV356_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HAP9015962.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1086..1946
                     /locus_tag="IV356_002305"
     CDS             1086..1946
                     /locus_tag="IV356_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP9015963.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2136..2840
                     /locus_tag="IV356_002306"
     CDS             2136..2840
                     /locus_tag="IV356_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP9015964.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2845..4680
                     /gene="walK"
                     /locus_tag="IV356_002307"
     CDS             2845..4680
                     /gene="walK"
                     /locus_tag="IV356_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HAP9015965.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4677..5993
                     /locus_tag="IV356_002308"
     CDS             4677..5993
                     /locus_tag="IV356_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015966.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5994..6863
                     /locus_tag="IV356_002309"
     CDS             5994..6863
                     /locus_tag="IV356_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015967.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6918..7727
                     /locus_tag="IV356_002310"
     CDS             6918..7727
                     /locus_tag="IV356_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAP9015968.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7830..8459)
                     /locus_tag="IV356_002311"
     CDS             complement(7830..8459)
                     /locus_tag="IV356_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HAP9015969.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8629..9921
                     /locus_tag="IV356_002312"
     CDS             8629..9921
                     /locus_tag="IV356_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP9015970.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9997..10659)
                     /locus_tag="IV356_002313"
     CDS             complement(9997..10659)
                     /locus_tag="IV356_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAP9015971.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10884..11168
                     /locus_tag="IV356_002314"
     CDS             10884..11168
                     /locus_tag="IV356_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HAP9015972.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11219..12844
                     /gene="groL"
                     /locus_tag="IV356_002315"
     CDS             11219..12844
                     /gene="groL"
                     /locus_tag="IV356_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HAP9015973.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4369 a         2265 c         2833 g         3679 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtc
      121 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
      181 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      241 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      301 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      361 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      421 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      481 atcataagtc tgatatcatg tttatgaaat gaaaaaagga gcggttatga tggaaaaaat
      541 gcgtcagcaa ttaatggagt gggggaagga actagaaaca ttccgtctgc ctcactggga
      601 agaactccct gacttagaac tttatatgga ccaagtcaga acgttagttg atcgttatct
      661 ttcacctgtg atacaaggag aaaagcatcc attgcttacc tcttctatgg taaacaatta
      721 cgttaaacta ggtttgatac cagcaccagt taaaaaaaga tataacaaag aacacgtagc
      781 atttttactt gcaatcacta cgttgaaaca agtattgact attcctgaaa tcaaagaagg
      841 gatattgttc caaggaaaaa cagtaggaat tcgtgaagcc tataatctat tttgcgatga
      901 acaagaagca gctgtgtgga tggtcagcca attagcacaa ggtaaatctc atccgcaaaa
      961 attcgaccag gcaacccctg tagaatatat tgctgtaaga gcggcaactt tatcgtttgc
     1021 aatgaaactt cttgcggaaa aaacgattgt tctagaaacc gaatatttaa aagaggagaa
     1081 aacaaatgaa aaacaataaa atcgcaattt tagtagattc aggtacggat gtgccagaag
     1141 aattgataaa aaaatacgag atgtatatga tcccattgaa aattatttat aaagatcagg
     1201 tatatacaga taaaattgac attacctctg aagagatcta tcaacgtttg ccagaggaaa
     1261 tccctggtac atctttgccg gatggtgagt cgatcacaga aatctttgag caaatcaaaa
     1321 aagacggtta tgaaaaggta cttgcggtaa caatttccag tggattgagc gggacatata
     1381 atgtggttcg tttaattgca caacagcaag aagaattgga agcatatgta ctagatacga
     1441 aaaatattgg tattggtgca ggtttttctg cgatccaagc agcaaaatgg ctggaagaag
     1501 gagtagaatg ggatcaactg atcagtaatc tgaatgagtt agtcgaaaga acaaaagttt
     1561 tctttaatgt tgcgacattg gaatatcttc aaaaaggtgg acggatcggt ttagttgctt
     1621 ctattgtagg aaccgcttta aagcttaacc caatcatctc atgtaatgaa gaagggattt
     1681 attacacagt aggaaaagct aggggacgta aaaaaagttt ggataaaacg gttgcttacg
     1741 tcaaagaaaa aatcggtaat gcaaaggtct tcaacttagc tgttgcccat ggggatgcga
     1801 aagaagaagc aattgaaatg gaagcgagac ttaaaagaga gttcccacaa gcaaaccaaa
     1861 tctactttgg ccagatttct ccggcattag tagtccacac tggtccggga ttattgggtg
     1921 tcggtgtaca agttttagaa ggataaatca aaaaaaggaa acactgaggt gaaaatcagt
     1981 gttttccttt tttattgaag ttagaacaaa aaataataaa gtattttgca ctttcatttt
     2041 aattttctct tttgttttat aggcaaagat gaaacaaaag cagaaatacg gtataatgag
     2101 aaggtatgac aataatatat aagaggtggc tctttatgaa aaaagtttta gttgtcgatg
     2161 atgagaagcc gatttcggat atcgtcaaat tcaatttagc caaagaaggc tatgatgttt
     2221 atactgcata tgatggggaa gaagccttgg aaaaagttgc tgaggtagaa cctgatttga
     2281 ttttacttga tttgatgcta cctaaaatgg acggcttaga agttgctcgt gaggtacgca
     2341 aaacttatga tatgccgatc attatggtaa cagccaaaga ttctgaaatt gataaagtcc
     2401 taggcttaga gttaggcgcc gatgattacg tgaccaagcc attttccaac cgagaattag
     2461 ttgcacgtgt caaagcaaat cttcgtcgcg gtgccacggc tgcgaaggaa ccagaagagg
     2521 cagcacctgc ggaattgacg attggtgatt tgacgatcca tccagaagct tacatggtga
     2581 cgaaacgagg agaaacaatc gagttaacac atcgtgaatt cgaactactc ttttacttgg
     2641 cgaagcacct tggacaagtg atgacaagag aacatttatt acaaacggtt tggggttatg
     2701 attattttgg agatgtacga acagtggatg taactgtacg tcgtttgcgt gaaaagatcg
     2761 aagataatcc aagccatcca aattatttag tgacacgtcg tggtgtcggt tactatttgc
     2821 gtaacccaga acaggagtaa ttggatgaaa agaaaagtcc gcttttttcg atcagtcaat
     2881 tttaagatcg ctattacctt tattctgatt ttattgatct cgatcgaaat tattggtgcc
     2941 tactttatac gtggtttaga acgttccacg atcaatacat ttattaaaga tatgaatcaa
     3001 acggtggaat cattagcaac aacaatcagc ccggaattga atcgaaaaga taatgcagat
     3061 gatgaagagg taaatgcgaa tatcaaaaga tttattgaaa acagtgcgac tagcgatatc
     3121 atcgaaatac gggtcgttga cgaaaaaggg atcatccgag gaacaaccga tgtcaatgaa
     3181 caaagcgctg tgggaaagaa aaatgattat gttgatatca atgatttcac gactaaacgt
     3241 tatgttgctt tagataacga cgataaacgg gtgaatatca atgttcaacc gatcctgtcc
     3301 ccgaccggcg atgccgttat cggggctctt tacgtcaaaa gtaatatcga acaaaaatat
     3361 tcggaaatca ataacacagc agtcattttc tttactgcct cactaattgc ggcatttatt
     3421 tcaatgatcg tatctgtttt agttgctcgt tcgattacac agccgatcgg tgaaatgaga
     3481 gaacaagcca ttcgaatcgc tagaggagac tacagtcgga aagtcaaagt gcatggacaa
     3541 gatgaacttg gacagctggc tgataccttc aatcagttag ctgaacgtat tgaagaagct
     3601 caagatacaa tggaagctga acgcaatcgt ttggatagcg tgctatccca tatgacagac
     3661 ggcgtcattg cgacagatcg caggggtaaa gtcattacga tcaatgatat ggctgtttcc
     3721 ttgctagata tcaaaaacga ggaagcaatc ggacaatcga ttttgacact tttagatatc
     3781 gaagaagaat atacgttgcg gaaattatta gaagatccaa acgaaatggt acttgaccgt
     3841 tcaaccagta cattggaaag tgatcagatg atcttgcgag tagacttttc tatgatccgt
     3901 cgcgaatcag gttttatcag cggattagta gctgtcttgc atgatgtgac agaacaagaa
     3961 aaaacagaac gggaacgtcg tgaattcgtc tctaatgttt cccatgaact tcgtacaccg
     4021 ttgacaagta tgcgtagtta tatcgaagca ttgagcgaag gtgcgtggaa agacgaggaa
     4081 gtagcaccaa attttttgaa ggtaacgcta gatgaaacag accgaatgat tcgaatgatc
     4141 aatgacctct taaatctatc tcgcatggat acaggtaata cccagcttca attagaatat
     4201 gtcaatttca acgagttagt gaattttgtt cttgaccggt ttgatatgat ggtgggaaat
     4261 caggaaaaaa attataagat ccgtcgtgaa tttacgcaaa gagatctttg ggtcgaagta
     4321 gatacagata aaatcatcca agtagtcgat aatatcatga ataacgcgat caagtattca
     4381 ccagatgggg gaacgattac ttgtcgctta ttagaaacgc ataataacgt ggttttaagt
     4441 atcaccgatc aaggattggg gattcctaaa aaagatctga accgagtgtt cgagcggttc
     4501 tatcgagtag ataaagcacg tgcaagagca caaggtggga caggacttgg attagctatt
     4561 tctagagaag tgattaaggc gcatcgaggc gctatttggg cagagagcaa ggaaggaaaa
     4621 gggtcgactt tttatatctc gctgccatat gaaccttatg aggaggaatg gtgggaatga
     4681 gaatctctga aaaagtcgtt cgtataggac tcattttgat ggttgcgtta agcatatact
     4741 tctcttatgc aatctggctg agcccagcag gaaaaagttc aatcaacgta gatgagacaa
     4801 acactcaaat gatcgagtct caaagcaatc gaaaaacttc cgaagtcttt cttccgcttc
     4861 atgttacatg gcaccattcg ggaatgatcc aagaaaccaa cagtgaaaat ctcgtgtacc
     4921 gattgcaatt gatcatcgat aaagcaagat ttggaaagct ttctgaagta gtttcaggag
     4981 acaaatcaca gtttgaacag gtgaaaaatc tgaactctgg ttttgagttg gcctataatg
     5041 cgcctttttt gctaagagaa tacaaggaag catttgattt agatttagat gtgtcgaact
     5101 tggcaaaaga aagcgaaaat atgtatttta ctagaataca attcgatcaa ggaaataaaa
     5161 aaatccgatt tttgaattat tcgaaccatc tcgtatatga agcaaatatt tcgttgaatt
     5221 ggacagatat caataaagaa ttaacagcaa aagacacaaa atggacagaa atgacaacag
     5281 aaccatcgac gatcgacacg caatatgcta cgaaacattc gatcaaactg aaaaagtata
     5341 gttatatcct gtcacagcaa ccctatacac tttttagaaa tgcttttttc cagaaaccag
     5401 atagcgtgaa aaataatgat gaaagcaatg aattgatttt ttacggtggg aatgaaacaa
     5461 tgtctatcca ttcggaaacg caagtagttg attttcgtgg agagctgcca gagaaaaaag
     5521 aaaatgctag tgtattttct gaaagtttcc cctatattag caaattaggc agttctttag
     5581 ggaacctcag atattttgac cgcagtgaca atacgatcga ttatcggata ttcgtggaag
     5641 gcttcccggt ttttgggaca gacagcagag gacagattgg tgtggaagtt ggcggtgaaa
     5701 cgaatggttc tgtgcaagtg aatatccaaa ccagtttgaa tacgattcaa gtgccgatac
     5761 cttcagacga agaagtagaa cttgcaagta cgaatgaaat catccagcag ttaaaagcta
     5821 agggagcaga tagcaacaag attggttcag tgatcgttgg ctatacatgg caaaatgtca
     5881 aagaaacgaa tcgtgtcgtt gatctcttac ctgaatggta tgtgaaatat aaagataact
     5941 ggtattcagc taacgacctt ctggaaaaat tacctggatt ggaggcgaat taattggatt
     6001 tcaaaaaaat cgaatggata tttttcgtcg cttttttagg gttgaatgtg tttttattca
     6061 gcagttatca tgacgcggta taccaagaaa acaatgtcat tcgctctaat cagactgaat
     6121 caatccaaca acgtctggct agcgacgata tcacttacac ggggaagatt tcgtctgaga
     6181 acaagcaagg ctattatctt agcgcggagc agaccaatct tagcacttca ttagcgaatt
     6241 atcgcaaggc tggtaaaagc ggcttgctgg caagtggtgt gtttttagac ggtgatgttt
     6301 tgacgaaatc tttatccagt tcagatgctg aaaagaacgt gatcgatcca gataaaatta
     6361 gtagttcctt ggaagatttt ttatctaaca aagacaatat tttattcggt aatgattatg
     6421 tgtacacgaa aaacttttct catttagaag aagaaccact agaaatccaa gcaagccaag
     6481 agtatgaagg catcccattc aatgatgata cagcaaaaat cgttctttct ttagaaaaaa
     6541 acgataatga ttatagcatc acgaaataca tgcagacgca tttatctgat atcgagcagc
     6601 tgcgcgaaaa gacggaactg tatacggaag aggaagcaat caatacattg tacatcaata
     6661 acaaaatacc aagaggatca aaaattttat ggcgtcagct agcttattcc tgtattctga
     6721 aagtccggga aaaaaatgtg tatgttcctg tttggcatgt agcgatcgaa acaagcgata
     6781 aagtggtcca aattgagagt gtcaacgctt tcagcaatac gatcgtgaca aacaatactg
     6841 taccaaaagt ggaagatcaa taaaaaagcg agtataatga aaaaagttta caaagtaaga
     6901 agggaagtag gagtcaaatg gctgaagaaa aaccagcttt taaaatcagt atcctagcaa
     6961 gtggaagttc gggtaattca ctttatatcg aaagtgaaaa aaaacggctt ttggtcgatg
     7021 caggacttag cggtaaaaaa atcacttcct tgatggctca aattgatcgg acaccggacc
     7081 aattagatgg aatacttgtg acgcatgaac atcgagatca tatacatggc gtgggtgtct
     7141 tggctcgtaa gtatcatttg gatgtttttg ccaatcagca gacttgggaa gcgatggaac
     7201 cactgattgg aaatgtacca gtggaacaaa aacatctatt tgagatgggg aaagtcagaa
     7261 cattcggcga tatcgatatt gagagtttcg gcgtctccca tgacgcagcg gctccgcaat
     7321 tttatcgttt ccataaagaa aatcggtcat tcgtcatgtt gacggacacc ggatattgca
     7381 gtgattatat gcgaggtgtc attgaaaatg ccgatggtta tttgatggaa agtaatcatg
     7441 atcttgagat gttacgcatg ggaccttatc cgtggaattt aaaacagcgt attttaggag
     7501 atagaggaca tctttccaac gaagacggtg cacttgtcat gactgatgtg atcggtaatc
     7561 ggaccaaacg aatctatctt ggccatctta gcaaggaaaa caatatgaaa gaacttgctc
     7621 atttaacaat ggaaaatgtt ttgaaagaaa aagattttgg cgttggacat gattttgaaa
     7681 tctatgatac agatccagat gaagcaactg agctattttc gatttaaaca gttcaatcaa
     7741 taaaaatata aaaagcagaa gataaaatca atcagggttg gttttatctt ctatttttat
     7801 ttttttagca tattaaaaaa ataaccgtat tatcgactga ctacactgat gtgctgcttt
     7861 tcatgtttct catccagtat ctcatctact aatgcaatcg cgtaatctgc catgctgatc
     7921 gtactgtcgc cagcagcgtt tctttgtaaa taatcatcac ttaacaaata agtacctgta
     7981 cgtttgccat gtggatcaaa taaagaagct ggactgatat aagtccaatg tagattttta
     8041 gattgtttca attttaacaa tccttcgtac atattgaaag ctgttggata gaagggtgca
     8101 tttttaggta cttggtcaat catacgagtc gtcttttctg tatctaagaa taacgaagag
     8161 gcacccccaa cgacaattaa gcgtgtatcg gttccttcaa gcatctcaat caaatgggac
     8221 aaagaagttt gatgcatttc ttcttttcct ttgggagcgt tgaaagcatc aacgacaaca
     8281 tcaaaagatg caagatcagt agttgtcaac tcaaataaat ccttttgtat aaacggaaca
     8341 tctgatggca atttttctgg atgacgcacg attgccgtca cgtctaaatc tctggacaat
     8401 gcttcgtcta aaataaatga acctgcatgg ccagtagctc caatgagtgc aattttcata
     8461 aaaaacctcc ttttttattc ctgtccattg taagcagttg ctgaatattc gtcaaagaat
     8521 ccgatttttg aaaagctcag tgcgcattcc tttcatggtt cgtgatcatt gggtatagtt
     8581 aaattaagaa aactgattga taaaaataga agttgaagga gataagaaat gaaagagtgg
     8641 ttagatcgtg cctttttacc aatgataaca tctgttgtga atcttagacc cttaactgct
     8701 ttgcgtaatg gaatgactta cacgatccca ataattattg ttggctcgct gtttttctta
     8761 tttgctcatt ttcctgtgga ttacatcgct cagtggatag acaaaacagg attttctatg
     8821 tattttacac aagtatacca ggctacattt gatgtgatag ccttttggat cgtttttgcc
     8881 attgcatacg cttatgcaaa agaagaagac atcgatcgct taccagtcgg cataacagcc
     8941 ttgtctgctt atctactgct tattcagcca ctaaatactc agatagatac tgtctggaca
     9001 ggtgctgaag ggatactagg agcagttaca actgggctca tcatcggatg gggctatgca
     9061 cgtttagtaa gacttgcgaa agggtggaag caaagagaga agatacctga aaatgtttgg
     9121 cagtctttta cttcattgat tccaatcatt gttatagtca cttttacgct tatcggttca
     9181 gcggtttttc aacagttgtt cagaatgact gttgttcaag gagtatggac atatgtccag
     9241 cttcccattc aatcgttcat agacacgttg tttggtgtgc ttttattagg tttttttgtt
     9301 ccgtttttat ggttatttgg tcttcatgga tctgcgatgg tcaatgggtt ggttagtccc
     9361 gtcttgcaag cgaattcatt agcgaatgca gaaatcttag cctcaggaca agagttgacg
     9421 gtggcaaatg gcggacatat cgttactcag caatttctcg atcagttcat gacggttacg
     9481 ggtgctggat tgacgttagg ggctgtattt tttatgacgg tttttgcgaa atcgaagaaa
     9541 tacagagaat taggaaatct tgctctttta ccagcctttt tcaacatcaa tgaatcaatt
     9601 attttttcca caccgatcgt gatgaacccg atgatggctg ttccttttat tttcgcaccg
     9661 gtcgtttcag gattgattac ctattccgct ttatattttg gattcgttcc tttatttaca
     9721 gcagtccaag tcccttggac aacaccgccg atcctctcgg gtttcttagt aggcggagtg
     9781 cctgcagcga ttttacaagg tatcgtgttg tcaattagtt ttttcattta tttcccattt
     9841 ttgaaaaaaa tagattctgc aaactgcaaa aaggaaagac agacaaaaaa tgatggagca
     9901 gcagaaaaga tgaacgacta aaaaacaaaa atactcctgt cgctttagat tgggaaaatc
     9961 accaatctag gatgacagga gtatttatag tcatgtttat actagccctt tttggacagc
    10021 taattgaaca agaacaacta atgtgttcat tcctacgtgt gtgatcatcg atgtccagat
    10081 ccgaccagtt gctttgtact ctaggctgaa gaagaaacct aggaaaaagt agattagcag
    10141 atgaccatca ttatgagcaa acgcaaacag caaagagctg atcactgctc cgacccaaaa
    10201 atttgaatat cgactgatga tccccagtat actgcggcgg aatacgaact cttccatgat
    10261 gggtccagca acagttgtcg ccaaaataaa agcgggtgct tccatgatca tctggatgat
    10321 attttgtgta ttctcggaag gggttgcttt gccaaacaat acagattcta acatgacagc
    10381 gatgctttgc agaatcaatg cgacaaagat tccaaccaat ccataaataa caatctttgg
    10441 agcagaagct ttttttaccg ctgattcgat cgctaagggt tcacgttgct taaaataaaa
    10501 aatagctagg acaacggcgc ctagtatata catgactgca gttgctgtga tcaattcaga
    10561 cgtagatttt acaagtccta tcgaagctag gatcaagggt gagataaaaa ttagaccata
    10621 gcaaaaaatg ctgaggaagc tatatttttt taaagacatg taattcctcc ttttaaggga
    10681 taacaagcat gcaaggcaag cttatatcga ttgatttcaa ttatatcata atttcaataa
    10741 gcagctgtca gaataaaatt tcttttcttt gatttaaaag cttgcaaaaa agagggagaa
    10801 tgagtattat taaaaatgta ggttagcact cgaaggttaa gagtgctaac agattaaaaa
    10861 aagagttatc ggagggattt atcgtgttaa aaccattagg tgatcgcgtc attatcgaag
    10921 tcgcaaaaga agaagaaaaa actgtcggag gaatcgtttt agcttctgct gctaaagaga
    10981 aaccccaaac tgggacagtt gttgcagtcg gtgaaggccg tttgttagaa aacggtgaaa
    11041 aagttcctgc cgctgtaaaa gcaggcgacc aagttatgtt cgaaaaatac gccggtacag
    11101 aagtaaaata cgaaggaaaa gaatatctga tcgtcgcagg aaaagatatc atggcgattg
    11161 ttgagtaaat ttggaagata aaaaaataat caaaaataat caatgaggtg aatcaatcat
    11221 ggcaaaagaa ttgaaatttg cagaagacgc acgcgcagct atgttacgcg gggtagataa
    11281 attagcagat acagtgaaag taacattagg acctaaaggc cgaaatgtcg tactagaaaa
    11341 atcttacggc tctccattga tcacaaatga tggtgtgacg atcgcaaaag aaatcgaatt
    11401 agaagatcat tttgaaaaca tgggtgcaaa acttgtatca gaagtagcat caaaaacaaa
    11461 tgatattgca ggagacggta caacgacagc aactgttctg acacaagcaa tcgttcgcga
    11521 aggtttaaaa aacgtaactg caggtgctaa tcctctaggc attcgtcgcg ggatcgaatt
    11581 ggcaacaaaa gcagcagtcg aagaattgca taatatctca actgttgttg attcaaaaga
    11641 agccattgca caagtagcag ctgtttcttc gggttctgat aaagttggac atttgattgc
    11701 tgatgcaatg gaaaaagttg gaaacgacgg tgtcatcaca atcgaagaat caaaagggat
    11761 cgaaacagaa ctagatgttg tagaaggtat gcagtttgat cgtggttact tatcacaata
    11821 tatggtaaca gataacgaca aaatggaagc tgttctagaa aacccatata tcttgatcac
    11881 agacaaaaaa atctctaaca tccaagatat tctgccattg ttagaacaaa tcttgcaaca
    11941 atcacgtcca ttgttgatta ttgctgacga tgtagatggt gaagcattgc caactcttgt
    12001 attgaacaaa atccgtggaa cattcaacgt agtagctgta aaagctcctg gtttcggcga
    12061 tcgtcgtaaa gcaatgcttg aagatatcgc tattttgaca ggtggtacag taattactga
    12121 cgatctaggt ttagaattga aagatgtaac aatcgaaaac ttaggaaatg cttctaaagt
    12181 tgttgtagat aaagacaata caacgatcgt agaaggttct ggagaaaaag aagcaatcga
    12241 agctcgtgtg caattgatca aaaaccaaat tgctgaaaca acttctgatt ttgaccgcga
    12301 aaaattacaa gaacgcttag ctaaattagc aggtggtgta gctgttgtta aagttggtgc
    12361 agctactgaa acagaattga aagaattaaa attacgcatt gaagatgcat tgaatgctac
    12421 acgtgccgca gtagaagaag gaatggtctc aggtggtggt acagctctag tgaacgttat
    12481 cagcaaagtt tctgctgtag aagcagaagg agacgtggca acaggtatca agatcgttgt
    12541 tcgtgcttta gaagaaccaa ttcgtcaaat cgctgaaaac gctggttatg aaggatcagt
    12601 gattgttgat aaattgaaga acgtggaact aggcactggt ttcaatgctg ctactggaga
    12661 atgggtaaac atggttgaag caggtatcgt agacccaact aaagtaacac gttctgcctt
    12721 gcaaaatgcc gcttccgttt ctgccttgtt attaacgaca gaagcagtcg ttgcagataa
    12781 accagaacca gcagcgccag cagctcctgc aatggatcca tcaatgatgg gcggtatgat
    12841 gtaagaaaaa gcaacttgct tatctacaac tgatcattag tgaaagacag ataaaaagag
    12901 gctggaacag aagcgtttaa ctccaagaaa taagaagaaa ttcacggaaa ttgcttttca
    12961 aatttttgtg aatttcagct tatttccgaa ggagttgctt ctgcttccgc tgtttatacg
    13021 tgtttagagc gtgagacaaa agtgttcttt acttttgtcc cacgctcttt tttgtgtgta
    13081 attataatga aaatagttat ttttaatagt tataatattt tatctattaa aagtaaatat
    13141 ccattc
//
LOCUS       DACDLM010000076        13085 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.078, whole genome shotgun sequence.
ACCESSION   DACDLM010000076 DACDLM010000000
VERSION     DACDLM010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13085
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.078"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            252..2417
                     /gene="acm"
                     /locus_tag="IV356_002316"
     CDS             252..2417
                     /gene="acm"
                     /locus_tag="IV356_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HAP9015974.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(2689..3174)
                     /locus_tag="IV356_002317"
     CDS             complement(2689..3174)
                     /locus_tag="IV356_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HAP9015975.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     gene            3654..4295
                     /locus_tag="IV356_002318"
     CDS             3654..4295
                     /locus_tag="IV356_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAP9015976.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            4314..4949
                     /locus_tag="IV356_002319"
     CDS             4314..4949
                     /locus_tag="IV356_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAP9015977.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            4967..5782
                     /locus_tag="IV356_002320"
     CDS             4967..5782
                     /locus_tag="IV356_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP9015978.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            6101..7537
                     /locus_tag="IV356_002321"
     CDS             6101..7537
                     /locus_tag="IV356_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP9015979.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            7726..10173
                     /locus_tag="IV356_002322"
     CDS             7726..10173
                     /locus_tag="IV356_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAP9015980.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            10403..11470
                     /gene="rlmN"
                     /locus_tag="IV356_002323"
     CDS             10403..11470
                     /gene="rlmN"
                     /locus_tag="IV356_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HAP9015981.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(11663..12766)
                     /locus_tag="IV356_002324"
     CDS             complement(11663..12766)
                     /locus_tag="IV356_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAP9015982.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
BASE COUNT         4489 a         2169 c         2766 g         3661 t
ORIGIN      
        1 tggaaatata gattgaaaaa atgaaagcaa taagtaaaat aaaatgaata tatgcgaaaa
       61 aataatttac attaggaaaa accttgtaaa aacagttttt tggcatattt attttttata
      121 aatatttgta aaataactat caatttttta gttaaaagat tggaaatgag tgggggagga
      181 attgaagaaa ggatttttga gagatgatat agtaggtttt atttttagtt aaaatagggg
      241 agatagaaaa aatgaaaaag tgtagaaata ttattttatc aatgttattt attattacta
      301 atataacatc actgattcct gttcatgtct atgcggatgc aggcagagat atcagcagta
      361 atgtcacttc gttgaccgtg gacccaacga atattacaga tggaggaaac ataaaagtaa
      421 aattctcgtt tgacgaaaaa aaacaaaata tccaaccagg tgattatctt tggatcaatt
      481 ggccaagtga aggaaatatt cgcggtgaag gattccaaaa agaaatccca ttaatgattg
      541 aaaataaaaa tgttggaact ttaacggtca gaaaagattc tgcgcaggtt gtgtttaatg
      601 aaaatattaa aaacctagac tcagtagaag gttgggggca atttgagata caggccagaa
      661 acgtaaccga taccggtgaa gaaaatacgg gaccattcac cgtgacgagc ggtgataaaa
      721 cagctactgt aaatgtgaca aagccagctt ctggttcttc ttctagcgtt ttttattata
      781 aaacaggaga catgctacct gaagatacta agcacattcg atggtttttg aatattaaca
      841 ataacggcac ttatgttgaa caaccagtta aaatcagtga tgaaatccaa agtggacaaa
      901 gattagatcc aagtacgttt gaaattaatc aaatacactt aggtgaacag aaggtttata
      961 gaggagaaga gggaatccaa caatttttac aagatttccc cagcgctaca tttaattttt
     1021 cagtaactga taattacatt gaaataacta taccaaaaaa ctttgtcaat cttaggaaaa
     1081 taatggtgag ttataagacg atcatagaaa acccagaaca aataaatttt gagaatcatt
     1141 cggaagcttg gtttaaagaa tttaataaac ctgctgttga tggagaaagt ttcaatcata
     1201 cagttaaaaa tatttcagct tctggtggag tcaacggtac agttagaggc gaattgaaga
     1261 ttttcaaata tatcaatgac acagagattg gtatcccaaa tgtgactttc gaattaagac
     1321 gagcagatga acagcctatt caaggacagt ctagtatcct gttgacttcg aatgaacagg
     1381 gagaagctag tatcaaaggc ctgcaagtag gagactatgt tgtaaaagaa aaagaagcac
     1441 ccaattggat tgattttgat ccactaagtt caaatgaact caaattctcc ataaacgaaa
     1501 atgatacaga gggagtcagt ttacctattt ataacaagaa aaaggttacg aacatcacag
     1561 caactaaaat ttggaacggt ggaaccactc caagaccgag tatttatttt aaattattca
     1621 gagcaagtac aaacaattgg gaaccagttc ctgatgcaga aacaaaacga ttagacaatg
     1681 gaataacttc agtgacttgg gaagatatcc aacagtatga tgatagtgga aacgaatata
     1741 cgtttaaagt gcaagaagta gatcaaaacg gaaatgatta tgtcccttca ggttatcaaa
     1801 aaattgaaaa cgggctagtc gttacaaatg agaataaaga agtcatttca gtctcaggac
     1861 aaaaaacatg ggaagacaat gagaaccaag acggcaaacg accgacgacg atcacagtaa
     1921 atctattagc cgacggtcaa ccgatccaac acaaagaagt aagtgaaaaa gatgattggc
     1981 gctatcgttt cacaaatctg ccaaaataca gagacgggca agaaatcatc tatactgtaa
     2041 cggaagacaa cgtgcccgaa tacagtacga cgattgacgg gtataacatc aaaaacagtt
     2101 atacaccgga aaaaacaaat atatctatac caggtagcca tataacaccg tggaaaaatt
     2161 ttccagagaa gacagagaga gagaaaatta gaaatctatt ctctcaaaaa ttgcaaatat
     2221 ttgctcatac aggagaatcc agcgaacaaa gaagcaatta tattagtaag agagctgtac
     2281 ctaaacagat aacaaataaa tcaaaaagca ttcttcctaa aacaagtagt aaaaaatcta
     2341 gttttgctgt aatcattggt ttattgatag taactatctg tgctgggata ttcttacaaa
     2401 aatataaaaa agtttagtta gaatataata ttttttgtta aatatgactg aaatcaaaag
     2461 aataaaattc cgatttataa tcgaaaaaag aagcattttt atatatgctt cttttttcgt
     2521 agaatcaata aatatggatt tggctaacta tggaagaata ctcgtattag ttttcagcgt
     2581 tcatactagt tgttacattg tttgattggc caaaagaatt tctgatatat tttgtgctaa
     2641 ataaagaaaa agacgcttga attgggaaat aagaaaacta ctctatcatt acaaattttc
     2701 ataaactggc agatgttcta agtaaacaag tatcttttca aagtcggaaa aatccataat
     2761 caacgtagtg gtattgatat ttggatgaaa gcctacggta tcttgacgat caatagcagc
     2821 atcgatcacg acttggattt ttttctcttt gtcgtgcatc aatgctaatg gagtcactgt
     2881 acctgctgga acgcctagga ggtcaggaag ctgttcttca gaaacaaaag ataagcgctt
     2941 ttcttttaat tgttcagcta gttgttttaa atcggcgtgc ttttcatcag gcaagatgac
     3001 aagatagatt tgttttcctt ttcttgattt caataataga ttttttactt gcggaccagg
     3061 tagggaaaaa gggacatttt tgactgacgt aatcgcagga tgatcgactt tttgaaaaga
     3121 gatacccagt ttttttagta gttcataagc ttcttgttcg gttgcacgac tcatcgcgca
     3181 tcaccctcct ttttttatta gtgtatcata aaaaagagtt gacaaatgaa aaataatcat
     3241 gtaaattaca cgtaaagtta aaacaaatga catcgaaaag aagagtagcc gttaggtgtt
     3301 tttagagagt ctctggttgg tggaaagagg cagcagttaa ccgtgaaaca catcttggag
     3361 tcgattttct gaagcgtata gtaggaaaat ccggggagcc cgttacagct gcggtcgttg
     3421 ctagatgacc agataaggct ggcttttccg tgaggagtcg gtaaaaaaag gtggaaccac
     3481 gtgattaacg tcctttgatc ttcggatcaa aggacttttt gttttcatct gaacggcaac
     3541 gactgtgtga ggttttttct gcaaggaaaa aataaacaga ggtggaacca cgtataatac
     3601 gtcctcttgg catttgccaa gaggattttt ttattttaaa ggaggaaaag aagatggagt
     3661 atttgattga agttatgccg caattattag taggagcact cacaacattg aaattatttt
     3721 tatttacctt gattggctca ttaccattag ggattgtttt agcattagga ttgtctttgc
     3781 attttaagcc gctacgctac ttgcttcaaa catatgtatg ggttatgcgg ggaacaccgc
     3841 tgttgttgca actgattttt attttttatg ggttgccgac gattgggatc gtttttgatc
     3901 gtttcgaagc agcactcatt gcctttatct taaactatgc agcttatttt gcagagatct
     3961 ttcgtggagg gatacaatcg attcctcaag gtcaatatga agcagcgcaa gttttgcaat
     4021 taagtccctt tcaaacggtg acgaaaatcg tcatcccaca agtgacaaag attgttttac
     4081 cttctgtagg gaatgaagtt atcaacttgg tcaaagattc ttccttgatc tatatattag
     4141 gtttaggtga cgtaatgcgt gctgggaaaa tcgcgatgga acgcgacgcg actttactgc
     4201 ctttgctagg cgtggcaatc atctatctta cattgactgg tattctaaca atcgtaatga
     4261 aacaagttga aggaaaatta aattattacc gctaactgat aggaggaaga aatatgattg
     4321 aattgaagaa agtgaacaaa gcatttggtg aaaaaaaaat aatcaaagat ttgaatctaa
     4381 tcattccaga tgggaaaaca ttagctatcg taggtccttc cggtggcggt aaaaccacgc
     4441 ttttacgtat cttggctggc ttagaaagtt ctgacagcgg agaattttat ttagacggtg
     4501 taccgttcaa cccattcgag cttaaaatga aagaacaagt tgtaggagtc gtattccaag
     4561 acttccagct atttccacat ctgaatattt ttgaaaacat taccttagca ccaaaaatgg
     4621 tattgaaaca gacaaaagaa gaatacacca aaaaagcaga agaattagcg gcttcattag
     4681 ggattagtga tttattgaat atctatcctt atcagctttc tggcggacaa aaacagcggg
     4741 tagcgattgc cagagcattg gctatgaatc cacgggtatt ggcttatgat gaaccaacaa
     4801 gtgctttaga tcctgaatta cgccagcaag tcgagcgttt gatcctatca ttgaaagaag
     4861 atggggtaac ccaaattatt gtcacccatg atttagtatt tgcagaaaat gtcggtgatc
     4921 aattactaaa agtttcccca attcattaag aaaggagaag atagagatga aaaaaaccag
     4981 ttttctattc gctttgatcg caggtcttct tctttttgca ggctgttcga acaaaaaaac
     5041 ttcagcagat aattgggcga ctatcaacga agagaaaaaa atcgttatag gtttagacga
     5101 tacatttgtt cctatgggat ttagagataa agacgggaag ctcacaggat ttgatattga
     5161 tttagccaaa gcagtctttg aacaatatgg gattacggta gactttcagc ccattgactg
     5221 gtcaatgaag gaatttgaac tgaacaatgg aacgatcgat ttgatatgga acggctattc
     5281 caaaacgccg gcaagagaaa agaaagtgca atttacaaaa ccttatatgg aaaacgatca
     5341 agtgctgatc acacctaaag aatcaggaat cacaaacttt ggacaaatga ataataagag
     5401 attaggtgcg caaaatgggt catctggtta tgatgtattt acgaaacaac cagaagtatt
     5461 aaaagagata gtcaaaaacc aagatgctgt tttgtatgat agttttaatg aagcattgat
     5521 cgatctgaaa agcagacggg tcgatggtct gctgatggat aaagtatacg cagactatta
     5581 tttgaaacaa agaaacgaac tagaagactt caacataaca aaaggttctt atgagagtga
     5641 ggattttgca gttggtgcac gcaagtcaga tagtacatta gtgaaaaaaa tcaatgaagc
     5701 cctagatcaa ctagagaaaa caggtgaatt ccaaaaaata tccgataaat ggtttggcga
     5761 agatgttacg ccgagaaatt aacaaatagg ggactgtgac aaaagacgtg tcacagtccc
     5821 tttttccgaa taaacagtgt tctcctgcca actccttgtg actcggagct gaatggcagg
     5881 ctcacaacct cttggtaaac ggtgttcaaa agccagtttt tcggtattaa gccaaattta
     5941 tgcaaaaatg tagaaagcca ttttcacaaa atttttctta ctactcgaaa ctaagcgact
     6001 ttttcacaac ctcctttaca tatttttatt ttgttgtgga aggggtttcg tgttattcta
     6061 aaagaggaac gattgaaggt tataggaaag gaagagatga atggaacaca aagaacttac
     6121 ctcatttcca aaagattttc tgtggggctc tgcttctgca gcgtatcaag tagaaggagc
     6181 ttggcaagaa gatgggaaag gagaatcagt ctgggatcga tttgtacgga tacctggaaa
     6241 gacatttaaa ggaacgaacg gtgatttggc agtagaccac tatcatcgtt ataaagaaga
     6301 tattgcttta atgaaagaac aaggtctgaa agcttaccgc ttctctgtag cttggacacg
     6361 gatttttcct aatggacgag gagaagtcaa tcaagctggg ctcgcttttt atgagagatt
     6421 gatcgacgaa ttgattgaaa acgatattga acctatgttg actttatatc attgggatct
     6481 tccacaagca ttgcaagatg aatataatgg ttgggaatca cgtcagatca ttgaagattt
     6541 cactcattat gcagaaacat tatttgaggc attccgcggg aaagtccatt actggattag
     6601 tttgaatgaa caaaatatct tcacttcatt aggttatttg ttagcagcac atccgccagg
     6661 tgtgacagac ccgaaacgaa tgtatgaagt taaccatatt gctaatttag caaatgcatc
     6721 tgtcatcaat aaatttcacg agttagaaat gcctggaaaa atcggaccaa gctttgcgta
     6781 tacgccaaat tatccaattg acagtaatcc tgaaaatgtt ctggctgctg aaaatgcaga
     6841 agacctgatg gccaattatt ggatggatgt ctatatgtgg ggaaaatatc cgattgctgc
     6901 catgaggttc ttagaagaaa aaggatgggc accaacgatt gaagctggcg atgcagaatt
     6961 gctagaatct gctaaaccag attttcttgg gatcaattac tatcaaacgg cgacgaatgc
     7021 attcaatcca ttaaacggag ttggtgctgg aaaaatgaat acgacaggaa aaaaaggttc
     7081 atcagaagaa actggagttc ctggaatgta taaaaaagtt gagaatccat ttgtcgaacg
     7141 aacaaattgg gactgggaga ttgacccaga aggattaagg atcggactgc gtcgtatcac
     7201 aagccgttac cgcatgccgg tactgattac ggaaaatggc ttaggagagt atgacaagtt
     7261 gacagaagat aaacaaatcc atgacgacta tcgaatcaat tacttacaaa gccacgtcaa
     7321 agccatcaaa gaagcaattt cggatggagc agaagtccta ggctattgca cctggtctta
     7381 tacagatttg cttagctggc tgaacggtta tcaaaagcga tatggatttg tatatgttga
     7441 tcaagacgaa acacaagaag gatctttgga acgatataag aaagacagtt attactggta
     7501 ccaaaaactg attgaagaaa atggagagaa cctttagttc acatacttaa aacaagaagg
     7561 tacggctgga tatggccgtg ccttttcttg ataaaatcat ttagaaatta agaaaaactg
     7621 taaaataagc tgaaaaatga aagaaagcgt cagttctttc aaacaaaact ttagttccct
     7681 tacttttttt tgtataatga aacttgatga aatgagggat aataaatggc acaaaagaaa
     7741 cggcctacta aaaaaaggaa aaagacgaaa aaaacgaaaa agcaaaaaca gcagcaggaa
     7801 caaatgctga cgattggtgt tgggtttgcc ttgattttat ttgctgtctt cggcttttta
     7861 aaattaggtt ttttaggaat attgattgca aacggctttc ggatcattgc aggaaatact
     7921 taccaaatcc tctgtctttt attagccgta ttaggatttt ggattgtcat taagaataca
     7981 gagttttcaa ttggtaaaaa ccgacgctgg tttggcggca tactctttta tttcggtatc
     8041 ttattattgt tacatgccca tttatttggc aaactccata ctggggaacc aaatatcatg
     8101 gggacgacat gggatttgtt agccagtgat ataaaacaaa gtcaagtaga caataacgtt
     8161 ggtggtggga tgattggagc aatcctttat cattttactt acttcttgat tgcacagcct
     8221 ggaagttatt tagcagcagt gctattactg gcaggaggag cattcctgtt cagtaatctg
     8281 gaaggctatc agctgttaaa tggtatccaa tcaattggag aacgagtaca ggaattattg
     8341 gaaggtgatc ctgccaagca agctcgaaag caagcggcaa aggaagagag aatgaaacag
     8401 cgcgcagaag cgaaagaagc aaggcgctta gctgcaaaag aagctgcaga aaaagaagct
     8461 gcagaatatg agaagaaaaa agcggtgagc cagcaaaggg aaaatactgc tgatgaatgg
     8521 caggaaccag aaaatacaga gccggagcag ctaagttttg ttccaatcga cagttttcaa
     8581 gaaaatatcc atcctgcgaa tctagagaaa ccagtaccag atacaccaaa acagaccaat
     8641 acagcagaag gtttttcaga tgagttgcca gaggatgacg gtacctcatt agaatttgag
     8701 attgaagcag aacaggaaaa tcaagactat gaattaccga cagttgattt gcttgattct
     8761 ataccaactg tggatcaaag tgatgagtat aaaaaaattg aaaaaaatat cggcgtatta
     8821 gaacaaactt tccaaagttt cggtgtcgat gccaaggtcg tcaaagccag cttaggacca
     8881 tccgtcacaa aattcgaagt ccagccggct gtaggggtaa aagtaagtaa aattgtgaac
     8941 ttaacagatg atatcgcgct tgctttagcg gcgaaagatg tccggatgga agcaccgatt
     9001 ccaggtaaat cactgattgg tattgaagta ccaaatggaa agatcagtat ggtttccttt
     9061 agagaaatca tcgaagcaca accaaaccac ccagataaat tactagaagt acctttagga
     9121 cgtgatgttt ctggacgggt acaaacggct gatctttcga agatgcctca cttactcgtg
     9181 gctggttcga ctggtagtgg gaagtcagta gcaattaatg ggattatcac aagtatatta
     9241 atgcgtgcta agccccatga agtaaaactg atgatgatcg atccgaaaat ggttgaattg
     9301 aatatgtaca acggcatacc tcatctgttg acgccggtcg tgacgaaccc tagaaaagca
     9361 gcgcaagcct tacaaaaagt agtacaagaa atggaagaac gatatgaaaa attcgcggca
     9421 accggagtaa gaaatatttc tggttacaat gaatttgttc aacagaaaaa cttggaaaac
     9481 ggaacgaaac atccaacctt accattcatc gtagtgatcg tagatgaatt agctgatttg
     9541 atgatggtag ccagcaatga agttgaagat gcgattattc gtttagcgca aatggctcgg
     9601 gcagcgggga ttcatatgat cctagctact caacgtccaa gtgtggatgt tatcacagga
     9661 atcatcaaag caaatgtacc ttccagaatg gcatttgcgg tatcaagcgg tacagattct
     9721 cggacgatca ttgattctaa tggggcagaa aagctcttag ggcgaggaga tatgctattc
     9781 ttgccaatgg gtgagaataa accgatccgt gtgcaaggag cattcatttc tgaccacgaa
     9841 gtagaacggg tcgttcaatt tgttacagat cagcaagaag ctcattatga agagaaaatg
     9901 atgccgacag atgaagttga aacgacaggt gctccagaac agccacaaga tgagctgttt
     9961 gaagaagcaa aagcacttgt cgttgaaatg caaacggcaa gtatttccct tctccaaaga
    10021 agatttcgga tcggttacaa ccgagcagca cgtttagtag atgaactgga agctcatgga
    10081 gttgttggcc cgtcagaagg aagcaagcct cggaaagtat tcattgagca ggaagaaaca
    10141 tcagaaacgt tgccggacga taatgacatg taaaacttgt gtgatgaagg gttgaaaaac
    10201 gaataaccaa taaaaagaca aggcatgatg ataccaaaag aaaaaatggt ttttttccat
    10261 cttttctaat acggtatgat gtcttgtctt tttagttttt gtgagattaa agttctattc
    10321 gatttatttg tgaagtattg cattaaggaa atgaatcatg tatagtatgt agcgaaactt
    10381 tgagaaaaag agggaaaata ctttggaaaa acagtccatt tatggcttga cgaatgaaga
    10441 attaatcaat tggtttatag aaaacggcga gaaaaaattc cgagctgccc aagtttggga
    10501 atggttgtat caaaaacgtg taagtaattt cacagaaatg acgaatctat cgaaacaatt
    10561 gatcgaaaaa ttatcggagc attttatcat caatcctcta aaacagatgg tcgtccaaga
    10621 agcttcggat ggtacagtaa aatatttgtt tgaactccct gataaaaaca tgattgagac
    10681 tgtactgatg agacaagaat atggcttgtc agtttgtgtg acgacacaag taggatgtaa
    10741 tatcggctgt acgttttgtg caagcgggct gctcaaaaag aaccgtgatc tgactgctgg
    10801 agaaattgtt gcacagatca tgatggtcca acattatttt gatgagcgca atcttggcga
    10861 acgcgtttca catgtcgttg taatggggat cggtgagcca tttgataatt acgacaatgt
    10921 aatggacttt ttgcatatca tcaatgatgc caaaggattg gcaattggtg ctcggcacat
    10981 tacagtttcc actagtggat tagcacacaa aatcaaggaa ttcgctaata acggcttgca
    11041 agtcaatctg gctatttcct tgcacgcgcc gaataatgag gtgcgaacat cgatcatgcg
    11101 gatcaaccga agtttcccaa ttgagaaatt gatggaagct gtggatgagt atttagagaa
    11161 aacaaaccgt cgaatcacgt ttgaatatat catgttgaat caagtaaatg atagaccaga
    11221 gcatgcgcaa caattagcag atctattaaa agataagaaa aaattagcat atgtcaactt
    11281 gattccatat aatccagtca gtgaacatga tcaatattct cgcagtccaa aagctgatgt
    11341 attgagattt tatgatgtat tgaagaaaaa cggcgtaaac tgtgtgatac gtaaagaaca
    11401 tggtacagat attgatgcag cttgcggaca attgcgaagc aagcaaatga aaaaaacagt
    11461 tgccaaataa tcgtatccta ctcgtttttt caattaccat aaaaggagca gttttcttaa
    11521 ttaaggaact gttcaactta aataagagaa aagattctat agcgaaagct ataaagcttt
    11581 ttttgacaag aaaaaccctc atcaagcaaa gaaatgtcct caatttgatg acagcctgct
    11641 tgatgggggt tttagcaatt atttaactga ttttcttata tccttgctgg ctttcttgtg
    11701 tagcatgata agtttctacg tcaagaatgg cctgtttaaa tttttctcgg gtgatttcat
    11761 aaggcacatg tttaatatca tttgttgcca tggctttatc taagattgct tctaaatcgg
    11821 tcgtgacatt gagattcatg tcggttaacg atactggaag ttggttcttt ttcataaaca
    11881 catagatttt atcaaacaaa tcgaactgct gatccatcat caataaggtc agtacaccat
    11941 aactgacaga tgctccgtga aggtatccct ccattttttc tagaacagtc gtaccgtaat
    12001 agaatgagtg tgccatagca gaattatagt tattgttaac taaaacagaa accaatccgg
    12061 tagtaacaat gatatccgaa acgacttgtt caattgcata tgagggacga tcgtcggcac
    12121 tatctttcaa tgcttgcgta ccataagtca agagacgatc aatgcacatt tttccgattt
    12181 ggattcctaa tctatccgtg tagcctagat catcgccacg agcagaaaaa gtagattcga
    12241 cttctttgga taaagcatcg ccaatacctg cccataagta tttatcaggt gcttcggcaa
    12301 taattgctgt atcaatgaag gtgtgtacag gtggttttga aggaaagaag agtccgtcca
    12361 ttacgccttc ttcgttatag atgacacata ccgcagtgac gggcgaacag ttcgaaccaa
    12421 tagtgggaaa ggtgaagact ggtttagcta gtttttcacc aatgactttt acagtatcgc
    12481 aagcacggcc accaccgact gcaaacagga cgtctgcttt ttggacactt tcatgctgga
    12541 tcaactgttc aatatttcca taagttgaat tacccccgta ccagagactg gcgacaacct
    12601 ctatttcctg tgtcaaagct acttttattt tgttttctgc ctttgaaagt gcagtcttcc
    12661 ctccaatcag cactactttt gtcccatatt ctttgacgat tccatttgct ttttcatacg
    12721 catctgttcc aatggtataa tttggtaaga aaacactttg actcatattc atttccttct
    12781 ttcttcgttg aaacgggtta aaattttaaa gagtgatcga tctgactgcg gctgtagatg
    12841 gagtagaggt gaacctaaga caggataagt gatgaataag gtggcatgaa caccttgaaa
    12901 tcatcaataa gtatcctaaa aacgaacaag tacaaaaaca ttgaaaacga caataatgaa
    12961 tttttgttcc tcttagtatt tctaccgatt ccctttgctt ttttgtaatt atctaaaaat
    13021 tctaaaaatt aagattatta tatgaaaaca ggttttattt gtcaattcat aattggtttt
    13081 tttta
//
LOCUS       DACDLM010000077        12659 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.079, whole genome shotgun sequence.
ACCESSION   DACDLM010000077 DACDLM010000000
VERSION     DACDLM010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12659
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.079"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(419..2428)
                     /gene="metG"
                     /locus_tag="IV356_002325"
     CDS             complement(419..2428)
                     /gene="metG"
                     /locus_tag="IV356_002325"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HAP9015983.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            2696..2974
                     /locus_tag="IV356_002326"
     CDS             2696..2974
                     /locus_tag="IV356_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015984.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            3071..3892
                     /locus_tag="IV356_002327"
     CDS             3071..3892
                     /locus_tag="IV356_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAP9015985.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(4177..5187)
                     /locus_tag="IV356_002328"
     CDS             complement(4177..5187)
                     /locus_tag="IV356_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP9015986.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(5199..6152)
                     /locus_tag="IV356_002329"
     CDS             complement(5199..6152)
                     /locus_tag="IV356_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP9015987.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            complement(6142..7212)
                     /locus_tag="IV356_002330"
     CDS             complement(6142..7212)
                     /locus_tag="IV356_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9015988.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            complement(7218..8261)
                     /locus_tag="IV356_002331"
     CDS             complement(7218..8261)
                     /locus_tag="IV356_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9015989.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            complement(8262..9203)
                     /locus_tag="IV356_002332"
     CDS             complement(8262..9203)
                     /locus_tag="IV356_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9015990.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            9287..9634
                     /locus_tag="IV356_002333"
     CDS             9287..9634
                     /locus_tag="IV356_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HAP9015991.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            complement(9704..11365)
                     /locus_tag="IV356_002334"
     CDS             complement(9704..11365)
                     /locus_tag="IV356_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP9015992.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(11911..12459)
                     /gene="aac(6')"
                     /locus_tag="IV356_002335"
     CDS             complement(11911..12459)
                     /gene="aac(6')"
                     /locus_tag="IV356_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAP9015993.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         3615 a         2563 c         2254 g         4227 t
ORIGIN      
        1 atctatattt tcaatcacac atataagagc acaaactaat tgaacataaa gtgatagaac
       61 ttataattaa cacatcaacg ctactgttag atataaatat agatgtaata aagtcattgc
      121 attcaaactt tatgaatgta aggacaataa aaaagagtac cagatgaatc aattaaaatc
      181 tgcccgaccc tttatcatta tgcttttttt ctgtttttac gattcctatt agtattattc
      241 taaattaaca aaaatcagcg aagctcgtac ttctttttct aggatttatt ttggatagtt
      301 ctctgtttct gtattatatg attggcttca agtaataaga aggaatttac gaaaattgct
      361 tctcaaattt cggaaaaagg gggtatgaca caactagtgt cataccccct ttgaatttct
      421 atgcgatttc tgagccattt ggcatggatt ttggtgcttc gattacttgt aaagagccat
      481 ctggtgcttc tgcagaaagg atcattcctt gactgatttg tccacgcatc tttcgtggtt
      541 tcagatttgc tacaatgacg acttttttcc cgatcaattc gcttggatca ggataaaatt
      601 cagcgattcc tgacaagatt tgacggtctt ggctgtctcc agcatctagt cggaattgca
      661 gcaacttatc tgccccttct actttttgac agttgatgac ttctgctact tttagttcta
      721 ctttttcaaa tacatcaaat ttgatttgtt tttctttcgt tgaaacaagt tctgtttctt
      781 ctggatccca tttgactgta tcttcgtttg tttgagtacc ttcagacatt ttttcttgaa
      841 taaaagcaac ttcttcttcc atatctaaac gtgggaagat tggtgtacct tttgcaacta
      901 cttttgttcc tgaaggaaat tcgccaaagt gtaatccttc aagattcatt gtttcagagt
      961 ccaatcctag ttgattgaag atcttctctg gcgtttctgt catgattggc tgaagtaata
     1021 tcgctgcgat acgcaaagat tcagctaaat ggatcatgac actattcaat tcagctttct
     1081 tttcttcgtc ttttgctaat acccatggtt ctgtttcatc aatgtatttg tttgcacgag
     1141 aaatcagcac ccagatttca gccaatgctg tattgaattc cattttttcc attgcatcat
     1201 ggtaacgtcc gacaacgtta gcagccgtcg tagacagttc actatcaaat ggagtgacaa
     1261 gtgaggcata gtcaggaacg agtccatcac aatatttgtt gatcatagca atcgttcgat
     1321 tcaataagtt ccctagatca tttgccagat cataattgac acgggaaaca aaatcttctg
     1381 gcgtaaagac accatctgac ccaaacggaa cagcacgaag caaataataa cggagtgcat
     1441 ctaaaccata acgttccaca agcatttcag gataaacgac atttcctttt gatttagaca
     1501 tttttccgtc tttcatcaat agccagccat gcccaaatac ttttttaggt agaggcaaat
     1561 caagggccat cagcatgatt ggccaataga tcgtatgaaa gcgaacgatt tctttaccga
     1621 ccatctgaac atctgcaggc cagtattttt cgaatagact ttcatcttcg gagccatatc
     1681 ctagtgcagt aatataattg gataatgcat cgatccatac atacaccaca tgtttcggat
     1741 cactcttgac tggtactccc caagtaaaag ttgttcgtga aactgcaaga tcctctaatc
     1801 ctggtttgat aaagttgttg atcatttcgt ttttacgaga ttctggctgg atgaattcgg
     1861 gatgttcttc atagtattcc aatagacggt ctgcgtattt gctcatgcgg aagaagtatg
     1921 attcttcttt taccaattct acttcgtgtc cacttggcgc tttaccaccg atcacgttac
     1981 cttcgtcatc tttgtacact tctgcaagtt gtgtttctgt aaagaattct tcgtcagaaa
     2041 cagagtacca gccttcatat tcacctaagt aaatatctcc ctgttctaat aaacgatcaa
     2101 atattttttg aacagctgct ttatggtaat catctgtcgt gcgaatgaat ttatcataac
     2161 tgatatcaag cgttttccat aatttcttga catcagccgc cattttatct acatattctt
     2221 gcggttttac acctagttct tctgcttttg tttcgatttt ttgaccatgt tcatccactc
     2281 cagtgagata aaacacatca aagcccatca accgtttata acgagcaatt gcgtcacatg
     2341 caatcgtagt atacgagttg ccgatatgaa gtttgccgct tggataatag attggcgtag
     2401 tgatataaaa agtttccttt tctgccacgg ggctcttcct cctttatcgc atgatgcgaa
     2461 ttcgtttcct tgctagtata ccataaaaaa agcatgctgt tagctttttt tcaaaatgaa
     2521 aaagactgga taaacgactt ctatctacgt tcaatctatc ctttaaaagg atgaataggt
     2581 tgaataaatg cgggtttttg ttttgtttca tatctactaa aaaacggctt tttatttctc
     2641 ccctcacacg tggtataata aagactatct atcttagtaa gggactggaa caatcatgca
     2701 gaagaaacat ctttttttta cacttagtat tgcttttctt tcattagcac atttaatatt
     2761 cagctatttt tatattcgta tgtatggtta ttttaacctc catgggcatt tgaacagttt
     2821 tatgacagca gcttggattt tgcgttttat cattgacgta tatatcgtta tttgtggctt
     2881 ctttgccatt cgtgaagagc ggtataaagt attgccgttt tatctgcttt tctttttatt
     2941 caatctcata cttccattta tttttcatat ttaaatgata acctagattt ttcaagtaaa
     3001 tccttggttt tttttcagag tctgctacaa taaggtaaaa agtactttta ctgtcaatgg
     3061 aggtggtcag atgaaccgtt ttgcttctaa agaagaagaa aaattatatt atgaacataa
     3121 agcaagtgaa gaagaatttc ttaactggta tcaaaaacag gaacgtccag aatatgacaa
     3181 gccctctttg actgtcgata tcgtactgat gtgctataac aaagaagaag atcagctgaa
     3241 agttttgttg atccaaagaa aagggcatcc ttatcgaaat tcatgggcat tgcctggtgg
     3301 ctttgtccaa aaggatgagt caactggaga aagcgtctta agagaaacaa aggaagaaac
     3361 tggtgtggtt atttcaaaag aaaatattga gcaactgcat acattcagta cgcctaatcg
     3421 agatccgcga ggctgggtcg tcacagtcag ctacttagcc tttattggag aagaaccgct
     3481 aatcgccgga gatgatgcca aggaagtacg ctggttcaca ctagaacgtc atagtaacaa
     3541 gatccattta tctagcggag aagtggctat ctcgcttgat ttagtcactg gagagtcttc
     3601 tggcaaagat actttggctt ttgaccatag tcaaatcatc ttgaaagcat tcaaccgtgt
     3661 agtcaataaa atggaacacg agccgcaagt tctacaagtt ttaggtaaag atttcacgat
     3721 tacggaagct cgaaaagtat ttgctaaatt cttagggatc gattataaaa cgatcgatca
     3781 ttccaatttt aagaaagcta tgctccaata tttcgatgag atcggtgaac gtcctgtagg
     3841 aatcggccgt ccttcaaaaa tctatcagct caagccgggg caccatgaat aaggttgtga
     3901 gcaaaagatt cagacctaat cattcaagaa aaaacgcaaa aacaactctt tgtgagttac
     3961 gttttttgtt tcagaatttt gatgtattcg taaactttct gaataaaaaa ttaacaatag
     4021 cagaaaaagc tcgtacgaac tttttctgct attgttttat tggtttgtca taattagtga
     4081 gcttttcttc aaaagaaaaa ttcctagaaa caaaagtcat taagactttt tattaacaag
     4141 gctaacccta acgctcctat cagtttcatt cattttttat cccttgataa ccgaatgtct
     4201 gcccattttt tctactactt ggctctttct tacggaattg ctttcttctg ctccgtcggt
     4261 attgatcaaa agaaattttt tattatacca ttgggactta taacgcaatt ttgttattaa
     4321 tttatgccag tcgtgaatag aaaaatcagc atgtgcctct tcttttggaa aagattctac
     4381 aaataagtag tcatattgtt tgaccaattt cccagataat tgttcaagat aatcttctcg
     4441 ctggttcttt tgtttcagat aaagatccat tacttttctc ttttgtttct gataattgct
     4501 tgcctgatct aacctgatct ttctatggtg agcggagcgg actttcacat tcaatttccg
     4561 ctgtgcatgt tgcagctttt cttctgtctg gtgaaatttt ggtaaagtta cttctagagg
     4621 tcgagatgtt tggatcaatg tcttcggatg ataggcgatc ccgatccatt tagctaaaga
     4681 ttcttttttt actggcgaaa catcacaaag tagtgcgaca taaaattctt cattatatcg
     4741 agcagaaatc gtagcggagc gaatcgatcc ttcaactggc cgatgctgat ttatcttgat
     4801 tagttctttt tgttttggta actttaagta gccattttcc agatagatcg tacgggtttg
     4861 gttgttggtc gtataagatt gccacatact ttttttcgtt ttaagctttg ggaagctggc
     4921 acgtcccttg aaataattgc gaaaagcccg atccaaatta agctgtgcat ttgctaaagc
     4981 aagactgtct acttctttta agaatgggta ttcttttttt aatgtagcgg gtgtgagcga
     5041 aaaattggct actcctgttt gttgccaact tttctgccgc tttttcagca aatggttata
     5101 ggtaaatcga gcacatccaa aagtacgaat caattgctgt ttttgttctt ctgtcggata
     5161 catacggaat ttaaaagctt ttagcatcta tgtccctcct agttagcaac cagaagagat
     5221 tccttttgtc gttttagttt ttttgcgtaa tatgggactt cctgctcagt tgcatagaca
     5281 aaatgttctg gtgcgatttc acgaagttga cgtacttgtc cgtcatctgg ttcaggttga
     5341 tatttgattc ttctgcgttt tctctcatgg tctggatctg gtagaggaat agcagataac
     5401 aaactttctg tataaggatg aacaccgtga ttatagattt catcacttgt tcccatctct
     5461 aataacaagc cgttatgcat tacaccgatt cggtcactaa tatgtttaac catcgacaaa
     5521 tcatgtgcaa taaatagata ggtcaattga tgttcttttt ggagatcttg caacaaattg
     5581 accacttggg cttggatcga cacatctagt gcagaaattg gttcatcaca aatgataaaa
     5641 cgcggtttta ctgccaatgc tcgtgcaata ccaatacgct ggcgttgccc acctgaaaat
     5701 tcatgaggat aacgagtacc gtggcttgga ttcaatccaa cagttctcaa tagatcatcg
     5761 actttttttg cacgctcttc agatgattta gctagtccat taacatcaat tccttcggca
     5821 atgatatctc tgactttcat acgaggattc aacgaagcgt atggatcttg aaagatcatc
     5881 tgaacatcat gccggaattt cgtcaaacct tttttatctt tgatcttcgt tatatcttga
     5941 ccgtcgaata atatctcacc atcagtaggt tcattcaagc gaatgatcgt acggccagta
     6001 gtggattttc cgcttccaga ttctccaact aaaccgaatg tttctccttc ataaatgtga
     6061 aagctgatgt catttacagc atgtacttca ttcttttttc ctacattgaa atactgtttc
     6121 aatcctttaa cttcaagtag tttatttggc atcagcaatt cctccttgac cgtaagtatg
     6181 tttttgtttc tctttaaaga tagcccagcg acgttggatt tcttctggcg gtgtcacttt
     6241 gggtgcctgc ggagcaagta gccaagttgc tgccttgtgt gtttttgata gttcaaaaaa
     6301 tggtggttct tgttctgcat cgattttcat cgcgaattca tttcttggat agaatgcgtc
     6361 tccttttggc gggttcaata aatccggtgg agaaccagga atagcataca atcgatcgtt
     6421 cgcactatct aatgtcggca ttgaaccaag cagtccccaa gtatagggat gttgcgggtt
     6481 gtagaaaatt tcttccgatg ttccaacttc aacgattctt cctccataca tgacagcgac
     6541 acgatcagcg acattcgcta ctacaccaag gtcatgagtg ataaagataa ttgatgtatc
     6601 gatttttgtc tgaatttctt tcagcagctc caaaatctgt gcttgaatag tcacatcaag
     6661 cgctgttgta ggttcatcag caatcaggat ttccggataa cataccagtg caatcgcgat
     6721 cacgatccgt tgacgctgac ctcctgagaa ctgatgcgga taactgttga tacgtttctc
     6781 agcttcgggt attccaacta atttaagcaa ttctaatgca gctttttgtc cctctttttt
     6841 tgaaacttta ttatgctttc taagggactc agcgacttgc ttcccaatgg gcatcgtcgg
     6901 atctaaagag gtcattggat cttggaaaat catcgctatt tctttaccac ggattttttg
     6961 catctctctt tctgattttc caacgatatc gttaccttta aagaggattt gaccagcatc
     7021 tatattggcg ttgcttgaca gcaagcgcat gatgcttctg gtcgtcactg attttccact
     7081 tccagattcc ccaacgatcg ccaatgtttc tcctttattc aaatgaaaat tgacaccgcg
     7141 aatcgctcgt acctttccag catacgtatc aaaagagatt tctaagtctt tcacttctaa
     7201 aattttcgtc atcgtcttca ctctttcatt ttaggatcaa aggcatcacg caatccatca
     7261 gcaagtaagt taaagccaat catgataacc gataaagtta ctgccggaat ccataataga
     7321 taaggcagat acaggaatgt cttgtaccct tcgctcaaca tcgttcctaa tgaagctgac
     7381 ggaggcgtaa gacctaaacc gataaagctt aaaaaggctt cgaagaaaat agcagatgga
     7441 atactaaaca tcatttgaat aataatgaca ctagagatat tcggcaaaat atgtttgaat
     7501 gcaattttca ttcttgattc acctaatgtc aatccagcta aaacatattc ttgatctttt
     7561 aatttcattg tttgtgcacg aacgatacgt gccattggta tccagtttgt gatggccata
     7621 gcagccacga ttgaaaaaat tcctggttca aaaacgacca acatcaaaat catgacaacg
     7681 aggtttggaa ttcctgataa gatttccaaa aaacgttgca tcacgttatc gacacgtccg
     7741 cctaacaaac cagaaaccaa cccgtaagct acaccaatcg ttacatctag taatgcagca
     7801 ataaatgcga tcagcaacga gattctcatt cccataaata agcggcttaa tacatcacgt
     7861 cccaaaccgt ctgttcctaa aaagaaattt acgtttgaag ggacgtttgc ttgagcatat
     7921 ttatcaacaa gttcaccacc aaccattgct tttccattca atccatcgat attgattccc
     7981 ggaatacgag gaggcaaatt gatataagcc acgttttggg cagttggatc atgaggagaa
     8041 acaaagattg tgatcacaga gatcaaaatg atgaccaata gtaaaaccat tgaaataacg
     8101 gcagctttgt ttttctttaa acggcgccat gaatcttgga taaaattcaa agaaggtgca
     8161 gtaatctgtt cacgttcttc ttcggtattt ttttgtaatg gaagaaattc atccgcaggg
     8221 atatctgcaa ctgtttcata acgctttggt atcatttcca tttatcctcg gctcccttct
     8281 gaaacacgaa ttcttggatc aactagaccg tacaatagat ccacgatcaa aataacaaaa
     8341 atcagcataa atgagtaaag gatcgttaca gccatgatcg taggataatc atttgttgtg
     8401 attgacttaa cgaattgttc cccgatacca ggaatagcaa agatattttc taccaccagt
     8461 gatccggtca tcaatgctac agctaacggt cctaataaag tcatcaatgg aatcaaacta
     8521 tttcgaagac catgtttaaa ggcgatttcc caacggctca atccttttgc ttttgctaat
     8581 tccacataat cactatgcag tacttccacc atttccgtac ggataaaccg agcagagtca
     8641 gcaagcggcg acatggccaa cgcaattgtt ggtaagattg tgtacacaaa gccatcccat
     8701 tttgcgattg gcaaaacttg taatttgatt gcaaagatat attgtaataa aacagcaaat
     8761 acaaagtttg gaatggaacg acctaatatc gctacgagtg tagaagatgt atctgcccat
     8821 gtattttgct tcatggcaga gatcgttcct aaaatcgtcc ctaggactgt tccaaagata
     8881 attgcctgta accctaactg caaggatggt ccgattcttc cagctaacaa atgtgcgact
     8941 ggctggtttt taaattggaa ggaaattcca aaatctcctt gaagcaaatt agaaagataa
     9001 atcccatatt gtacgataac tggtttatcc aaaccgactt gtttatttag catctcgatt
     9061 gtttcaggac tcaaacgttc ctgattcgta tatggcgtgc ccggcagcaa ttgcatcaag
     9121 aaaaaggtga ttgttgcaat taaccaaagc gtgatgatca tgaaaaagac acgttttaat
     9181 acatatttga tataactatt cactaatgtt tccccctagc ttttgacttc tgacagatgt
     9241 ttcgctacat tattagataa tgaaccaaaa ataaaggagc aatcaaatga aaaaaaaatc
     9301 tatcccctac gcagtagctt ttctactgat tctggttatt ttaataaaaa atctcatcaa
     9361 ccattccttt acactcattc aattatctaa tgatctattc ttatggtcat tgccgtttct
     9421 gattatcggc ggttttttat gggtcttttc ttcgggtttc ttcgatcatt ttcagcgatc
     9481 ggtccatctt gcacgaacaa ggaaccgaaa gaaaaaacca gaattttcct cgctctcgtc
     9541 tgccagctac ggtatgtaca gcttttggct gatcattgcc ggaatactaa ttgctctttc
     9601 tgctattttc atgctttttt ctttgttagg ataagtgaat atgagaacga ggttgcgaca
     9661 tttgccgcag cctcgttttt tctcatgctc acggtattaa cgattattct tcaacgtatg
     9721 tccatttgta atcccatgaa gcgcctgccg catggtgaac gatacctttg attttttcat
     9781 tcactaggtg accttctgct ttttggtaca ccggaacgac acccatatca tcagagatga
     9841 tcttgattgc tttttggaaa tcatcccaac gggcttgttc atcgccagcg tctgttgatg
     9901 aagctgcttt aactgcttcg tcatattctg cattgctcca gcgaccacgg ttgtatgaat
     9961 tacctgtgac aaacaaatca gtaaagctgc ttgggtctgc atagtcagca gcccatccgc
    10021 ctagtactgc gtcaaaatca cccgaagttg agcggtcaag acgtacagag aatggaacag
    10081 gtgttggttt gactgttacg ccatccaagt tttcttggat tgagttttga acatattcga
    10141 ttactttttt cgatgaatca tcatcagaag ccatcaaatc aaattctaaa gaatcaacgc
    10201 ccaattcttt tttcgctttt tcccaatatt cttttgcttt atctttgtca taagaaacta
    10261 attttccagc ttcttttgca aagtcttcgt tcgttgttgg actttttacc atatctgatg
    10321 ggatcaatcc tgtagagaca actgatccgt cacctagtac ttgttttact aaagcttcac
    10381 gatcgataga ataagaaata gcttttctta ggttcacatt gttgaatggt gaattctttt
    10441 cacgttgatt gaattcgata tagcttgtcc gcgcttcttt aacagaagta taagctggat
    10501 cgtttgcgtt ttgctgtgct aactcaccag acaagatcac gtcatctgct tggccatctt
    10561 tgaataagtt caatgcagta gaagattctt ttactacact gactttgatt tcagaaagtt
    10621 ttactgtatc tttgtcccag taatgatcat ttttcttata agtccattct gtatctgttc
    10681 ctggtccatc aaaatcttct aatgtgaatg gtccattata aacagcttta tcacttgcag
    10741 atgcataggc atccccattt tcttccacta cggattgttt ttgtgggaaa aatgatggga
    10801 aagcaagcag atattggaaa tatggtgttt gtttcgtcaa tttgatttct aattcatagt
    10861 caccaactgc tttgatccct agttctgatt tatctttctt tccagctgta atgtcttctg
    10921 cattttcaac tggcgcatac aggtaagcat attcagaagc tgtagctggg tctactgttc
    10981 gttgccagcc ataaacgtaa tccgctgctg taacaggatc accatttgac cattttgcgt
    11041 cttctcgtaa tttgattttg taagttaatc cgtcttcact gacttctgcc aactcgctag
    11101 ctcctgccgg ctgtggtttg ctgtcttcat caagacggta aattccttca taaacgttat
    11161 tcaatgctgt aaaactgatt gtatctgttg caactgataa gtcagctgta ggcatttctt
    11221 gaggcacgac taagttaaat acgcctcctc catctgctga accgcttttt gctgaactac
    11281 tgcttgtggc tgaactgccg ccataacatc cagcaagtac aaggccgcat accgcaacca
    11341 aaccaaatgt aaatttcttt ttcattttac gtaccccttt attggaattt tcagaataat
    11401 taatattttc tgaagttgtt taagagttta atgaataatt attaaaaaat caacactttt
    11461 ttttgtcttt ttcataaaat aatgattttt tcgtgaggtt tcaaggaatt tttcagaaaa
    11521 aatagctttg tacaaggttt tccatggtct tccaaaagcc attaaataat tttcgttata
    11581 ttgtctatta ttgccataca aagataaaaa agaataaaca aaaagaaact gtgacaaaag
    11641 tcttgtcaca gtcccttatc tgaataaacg gtgttcaaaa gccagtttct cggtattaag
    11701 ccaaatttat gcaaaaatgt agaaagccat tttcacaaaa tttttcttac tactcgaaac
    11761 taagcgactt tttcacaacc tctggtacac ggtgttccaa aagtagcttc ttcggaaata
    11821 agttggaatt tcacaaaaat tcaagaagta attttcgtaa attccttctt atttcttgaa
    11881 gctgattact tctgtcacaa cctcttttta ttattgagaa tttggtcgag gaataatcgt
    11941 ttttgccatc caaatatccg gtttgtccca gccatttgca tttggtaaga cacctacgat
    12001 tttataacct aatttttcat agaattcata cggatgttca cgaaggttct ggatggaagc
    12061 cactttatca aatgtatgct catacaggtc cgtttgactt aacgttgttc catggtctaa
    12121 atcatccgta cctaaataaa tcgtgattcc tcctctggaa gctacttctt tttctaagta
    12181 attgactaat cgagtaccta tttggttctt tcgtcgggag ctttctacaa ctaatggatg
    12241 caattcccaa cctgtgatac cgtattgagg gattgcacca ataaatccta ctaactcatc
    12301 ttggtctacc gctgctaccg cgattcgttc tggattcatc atttcttcta cttcttctgc
    12361 cgagctgtct ccatattctt ccggccaagt cagtctcagt aaatcagaaa gctgatcttt
    12421 caatactgga ttattacggt caaattcact gattatcata cgtcttcccc cttgttcttg
    12481 cttattctaa cagtcctttt gaaaaaacga aatgttctcg ctcaaaaatc tttagctacc
    12541 aatcagtatc tctattcttt cattatttat cttacttata aaataaaaaa attatacaga
    12601 aacactttat tcaaaatagg aaagatcagg aaagccatca attggaggaa aaaactctg
//
LOCUS       DACDLM010000078        12323 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.080, whole genome shotgun sequence.
ACCESSION   DACDLM010000078 DACDLM010000000
VERSION     DACDLM010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12323
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.080"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            51..260
                     /locus_tag="IV356_002336"
     CDS             51..260
                     /locus_tag="IV356_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9015994.1"
                     /translation="MICYISFLILGLPQAVFPEMFSGDWGIVSYSILTLIAMVLGTSF
                     YNAFVSKHVEEYEVLMYLKEKKTSN"
     gene            467..667
                     /locus_tag="IV356_002337"
                     /pseudo
     CDS             467..667
                     /locus_tag="IV356_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298761.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1379..1984)
                     /locus_tag="IV356_002338"
     CDS             complement(1379..1984)
                     /locus_tag="IV356_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP9015995.1"
                     /translation="MAKIGYIRVSSQDQNLDRQLAMMEDLNIDKLFQEKASGKDIQRP
                     EFQKLLNYIREGDCVIVASLDRLGRDYEDIKNTVTFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAKKAGRYKGRPIEYSENSTDPQ
                     KRLVFKTVVDMLNQGVPVAEIAKENGLSRPTIYKIKKANDL"
     gene            2166..2501
                     /locus_tag="IV356_002339"
                     /pseudo
     CDS             2166..2501
                     /locus_tag="IV356_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2666..2893
                     /locus_tag="IV356_002340"
                     /pseudo
     CDS             2666..2893
                     /locus_tag="IV356_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613886.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            3019..3990
                     /locus_tag="IV356_002341"
     CDS             3019..3990
                     /locus_tag="IV356_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP9015996.1"
                     /translation="MKTTMKDVAALAGVGVGTVSRVINGVKVKEVTKEKVMAAISELN
                     YEPDEYARGMKTNSSNTIALILPTIWHPFFSEFAYYVEEALSQKNYKLFLCNANGSAE
                     KEKEYIQMVKQSKVDGIIGITYSDIDKYVSSNLPFVSIDRHFSEQVSYVTADNYLGGQ
                     IAAQELLTRNCKNLCYVGGVSPYPNETNNRKAGFYNICEENKIAVKVLDMPEPISNLE
                     EQLLAFFSDNPEIDSIFTINDFMALDVIKAQKKLGKEAPKDFQIIGFDGVKLSLQKDY
                     LLSTIVQPIEEMAKVSVETLMAMILNEEPPKRVVVPVFFHAGETTKE"
     gene            4130..5443
                     /locus_tag="IV356_002342"
     CDS             4130..5443
                     /locus_tag="IV356_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAP9015997.1"
                     /translation="MKKRMLAIAAILALTAGGLAGCGSKEKSSGSSDPGEIKIWVQFS
                     DETPEGKAWAEIVNNFNDEYEGEYKAVTEYIPRSGSGGGYEDKVNAAITTNTLPDVIT
                     LDGPNTAAYAHSGVIAPLDDYLKDADMDDVLDSIIQQGTYDGKMYAFGFSESSVGVYY
                     NKSLFKDAGITEDQLPTLEDPWTWTEFQAICQKLTDKYKTPAIDMQMASGDEMLTYAY
                     TPFIWSNGGDVVNADGTKAEDYFNGKKSVEALEFIQELVEKGYTTISPIEKGFETGKY
                     AMMLSGSWTMADLEENYQEIDYGILPYPVSDATGELVSPTGSWQLAMTEKTEKKDASA
                     AFIKFATSTESSRIMSLGNSVLPIRNSTVDLIKDEVSEGMQVLIKQNQLSGHARPVVV
                     AYPQVSRAFQQAVQDISYFEENPDVQKVADSRAAEMQQAIDTSLK"
     gene            5486..6352
                     /locus_tag="IV356_002343"
     CDS             5486..6352
                     /locus_tag="IV356_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP9015998.1"
                     /translation="MKDNLIGYGFLAPALLLLTIFLIIPVIMVIYYAFTDYYLLTPDA
                     RQFIGLENFKRLFADPIFVKSIWNTAKFVVWIIPVQIGAALGMALIINKNRKGNIFFK
                     VAFFAPVVMSLVVISILWLYLLNPNEGLVNTLFAKIGIASQPFLTSPKQAMYTLVFVS
                     AWQGAGYQMLLFLGGMQNIPQDVYEAAEIDGFSKFQQFRYITMPLLKPTAIFILLTTL
                     ISAFKLIIQPMVMTQGGPMNSTMTMVYYIYQTGFTDRMVGYSSSIALIFTTMIGLITI
                     AQRKLVKEDDPA"
     gene            6349..7197
                     /locus_tag="IV356_002344"
     CDS             6349..7197
                     /locus_tag="IV356_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006639650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP9015999.1"
                     /translation="MTKKFGPLMIVEYCLLFLLAALFIFPMLWMVVSSMKPEADVYQN
                     LASFKAFLPSLNPANWFKTYQEVISRFSVGTYLLNSIFYGLTFACGSIIVNSLAGFAF
                     AKVNFSGKKIIFGALLALLIVPMETVLIPQFTIVNSLGLVNTRLAVILPAMASAFNIY
                     LFRNFFIAIPEEIIESAKLDGANIVKIFFHIMLPMSKPAIATVGVLSFISSWNDYIWP
                     LMVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTIATIPLIIVYIVAQKYILQGLGG
                     SGTGIK"
     gene            7211..8683
                     /locus_tag="IV356_002345"
     CDS             7211..8683
                     /locus_tag="IV356_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HAP9016000.1"
                     /translation="MLQKLLKANEFIEKNAQTVNQEYRNKFHLMAPIGWMNDPNGFVY
                     YQEEYHLFYQYYPYDSIWGPMHWGHAKSKDLIHWEHLPVALAPGESYDKEGCFSGSAI
                     EKDGKLYLIYTGHNVVEGQVRQVQCLAVSEDGIHFEKYAGNPIIAEDHLASVATTEDF
                     RDPKVFQRKEDYFTVVATKTADARGQIVMFHSKDLLTWEFYSVLLEGTPEQGIVWECP
                     DLFELDGKEVLILSPIQMTPQGNAYQNTNSTVAFIGTVDWQTGKFLVENFHEIDGGLD
                     FYAPQTCENEAGQRIMIAWMQMWQRKIPTNDLGHGWSGSMTLPRELRVADNQLLQRPV
                     SSIYQVIDPQERIEWAKTEENRFLLKDLVYDQHYLRLEINLKQATKLELHYAKGPDHT
                     LLLNYDVERECFTASREHMPYDLSGAEKEVLKKRSVTIPLENNCLTIEIFRDTSAIEL
                     FLNDRLTMSTTFYETEKGQDFLLLADSEVTFSLESGLINL"
     gene            8700..9572
                     /locus_tag="IV356_002346"
     CDS             8700..9572
                     /locus_tag="IV356_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP9016001.1"
                     /translation="MIYGSIEAGGTKFVCAISDEEMTIKERVSFPTTTPEETIPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKVAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
     gene            complement(9808..11190)
                     /locus_tag="IV356_002347"
                     /pseudo
     CDS             complement(9808..11190)
                     /locus_tag="IV356_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726506.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            11652..11933
                     /locus_tag="IV356_002348"
                     /pseudo
     CDS             11652..11933
                     /locus_tag="IV356_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            12007..12323
                     /locus_tag="IV356_002349"
                     /pseudo
     CDS             12007..12323
                     /locus_tag="IV356_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISS1N family transposase"
BASE COUNT         3837 a         2095 c         2480 g         3911 t
ORIGIN      
        1 atttaaaaag aaaagtgaca gataggaata aaaacttatt aaatgtagtt atgatctgtt
       61 atatttcatt tctaatacta ggtcttccac aagcagtgtt tcctgaaatg ttttctggag
      121 actggggtat tgtcagctat tctatattaa cattgattgc tatggtttta ggtacttcat
      181 tttataatgc ttttgtaagt aagcatgttg aggaatatga agtattaatg tacttaaaag
      241 agaaaaaaac aagtaattaa tatgagaaca ccacgcatag tttttatttt gagatattct
      301 agaatgaaac acattaagaa cgaaagcaaa gcaaaagacg ccagaacttc tactaccttc
      361 taagtttttt catatttgtt tgttatgcta tacatagatc tgcataatta gacttgcgct
      421 gcccgttatt gaagtttcag gcagcgctct ttttggggga tcgataatgg aagaagaaaa
      481 aatatttgag aaacgctggc agctagcatc aagtgaacaa agagcaagat acaataattt
      541 gatcacctcc taccccactg ttgactagac atataaggaa aagaaatact tactttggct
      601 gtgccagtta gatatagata cctttgaaac atttgaagtg atcctagata aaattaaaca
      661 gaattgatca gaaacaagcg aagccttctc tcggttcgct tgttttgcta tttattagtt
      721 ggctcagggc aactctaagc tcgtttgaaa gaaaaccgat ggataatccc cttgtttgta
      781 ccactttaga atacatggat gtacgtattg ccattgactc ctattagtta ctgaaaaaaa
      841 atttaaacaa gttgagtatt gcagataaat agctccagtg aggtgaataa ctgctccact
      901 caaggcaata gatagctcca tccagggcaa caaactgctc cactttcata tttaatagat
      961 gaataacctt ctgtataata gaaaggcata cctttcggta tgacaactta tacagaatgt
     1021 tattttattg gttcactatc gaaaaatttt ggagctttat ttttccggta tttctcaacg
     1081 aacgattagt ttaactgtgg gaagctccag acatacgatt cgagaagtta cttctcgagc
     1141 agacaggaag ggggtgactg aactaaccgc tgatatgagc gatacttggc tgtaggaata
     1201 tctttttccg gaaaaacaaa caacagcacg aggttacctt cctgtagact gggaatatgt
     1261 tcataaagaa ctaatgaaaa agaatatgac attgaaactc cttcatagag aatatggggt
     1321 acatggaaca tagaaacgaa aatgcacggt agaaaagcga atgaatatag tataaattct
     1381 acaaatcatt cgctttcttt attttatata tggttggtcg agagagacca ttttctttgg
     1441 caatttctgc aactggaact ccttgattta acatgtccac cacagtttta aagactaatc
     1501 gtttttgcgg atctgttgag ttctcagaat attcaattgg tcgcccctta tatcgaccag
     1561 cttttttggc caataatact ccttgccgct gacgttcacg gattttctca cgttcgtttt
     1621 gtgcaatata acttagcaat gataaaaaca tatcgaacat agcagtatct aggagttcat
     1681 ttccagtatt aaaatctaaa aactgtgcat ctagtatttt taatgctact tttttctgtt
     1741 tcataaaggt aactgtattt tttatgtctt cataatctct gcctaggcga tccagtgatg
     1801 caacaatgac acaatcacct tctcggatat aatttagtaa tttttgaaac tcaggtcgct
     1861 ggatatcttt accactggct ttttcttgga ataatttatc aatgttaagg tcttccatca
     1921 ttgccaattg tcgatctaaa ttttgatctt gtgaagacac tctaatatat ccaatttttg
     1981 ccataaaaac tccttttaaa aaatgatata atttacatgt aaaatttact tgtagtttta
     2041 ctgttatcat agcattttta aaaataaatt ttaagtctac ttataattta ctttggaggt
     2101 tttgaatgaa tgaaattaag cgcaataaaa attcttttgg tgtttattta ggagagccta
     2161 gctcggaaca gttaaataaa ggtgaagctc gtcatgctct atgtcgaaat atattttatg
     2221 gtagaaaagg caaactttat caaacttatt acgacggtat ggaggaacag ctcaacgcat
     2281 taggattagt aactaatgct atcatatatt ggaattcact atatttagaa aaagtctttg
     2341 aacaaattaa aacggaaggg ttcgactgtt ccgaagaagt gttacgcaag caatttccat
     2401 taattagtga tcacattaat tttgttggca aatatagttt ccgctatgaa aaagaattat
     2461 cgaatggaat actacgtccg ttaaatatag agaattattg agaatgttcg tcttttggtt
     2521 cctaccgtgc attttcgcac ggatgttcca gatactattt ttgaatgtat aaaattgaaa
     2581 acacaagaat actaataaat caacgattct tgtgttttta atttttcact accgtgcatt
     2641 ttcgtttcta tgttccatgt accccaatct tgaaaaatta attaaagact tagataaagc
     2701 cattgacgac ttagtcgtgg tgctaccgga gtatcaatgt ttaaccagta tcccaggtat
     2761 tggtcctgtt taggctgctg gaatactcgc tgaaattggt ccaattgaac gtttttctga
     2821 tgaaataaaa ttgacaaagt atgccggcct atattggcga cagagtcaat ccggtaaatc
     2881 tgaatacgaa aattttttta cgaaaagctt cacgtctaat atctatttta aaataaaaat
     2941 attcctgcta atttggaatc gtttccttct tttggtataa taatacctga aattcttttg
     3001 agaggagttg ttcgtgaagt gaaaactact atgaaggatg ttgctgcgtt agcaggagtt
     3061 ggtgtgggta cggtatctag agtaataaat ggagtaaagg tgaaagaggt taccaaagaa
     3121 aaagtaatgg ctgcaattag tgagcttaat tatgagcctg atgaatatgc cagaggtatg
     3181 aaaacgaata gtagcaatac aatagctctt attttaccta cgatttggca tcccttcttt
     3241 tccgagtttg cctactatgt agaggaagct ctcagccaaa aaaattataa gctttttttg
     3301 tgtaatgcga acggcagtgc ggaaaaagaa aaagaatata tccaaatggt caagcagagt
     3361 aaagtagacg gaattatagg tattacctat tcagacattg ataaatatgt atcatcaaat
     3421 ttaccatttg tcagtataga ccgccatttt tcggaacagg tttcttatgt aacggcagat
     3481 aattatttag gtgggcaaat tgccgctcaa gaactactta ctcgtaactg taaaaacttg
     3541 tgctatgttg ggggtgtttc accttaccct aacgaaacaa acaatcgtaa agctggtttt
     3601 tacaatattt gtgaggaaaa taaaatagct gtgaaggtat tggatatgcc tgaaccaatt
     3661 agcaatttag aggaacaatt gctcgctttt ttttcggata atcctgaaat tgatagcatt
     3721 tttaccatca atgatttcat ggctttggat gtgataaaag cccaaaaaaa actagggaag
     3781 gaagcaccta aggattttca aattattggt tttgatggag tcaagctatc gttgcaaaaa
     3841 gactatttac tatcaacgat tgtacagccg atagaggaaa tggccaaggt ttcagtagaa
     3901 acactcatgg cgatgatttt aaatgaagaa ccgcctaagc gtgtggtagt accggttttc
     3961 tttcacgctg gagagacgac taaagagtaa aaaaccggtt tataacgatt tttttgagat
     4021 aggttgacag aaagtgattt caatgatatc ttaaaaccaa ttaattggaa acgttaccaa
     4081 ttaattgaaa aataaaacgg aaacgtttca aaaaatagga ggaacatcga tgaaaaagag
     4141 aatgttagca attgcagcaa ttttagcatt aacagctgga ggacttgcag gatgtggcag
     4201 taaggagaaa agttcaggta gcagtgatcc aggagaaatt aagatttggg ttcagttttc
     4261 tgatgaaacg cctgaaggaa aagcttgggc agagattgtg aacaatttta atgatgaata
     4321 cgagggtgaa tataaagctg ttactgagta tattcctcgt agcggaagcg gcggtggata
     4381 tgaggataaa gtaaatgctg caattacaac caataccctt cctgatgtta ttacgttaga
     4441 tggaccgaat actgcagctt atgctcattc aggagtcatt gctccattag atgattattt
     4501 gaaagatgcg gacatggatg atgtattaga cagcattatt cagcaaggaa cctacgatgg
     4561 caaaatgtat gcgtttggtt tctcagagtc cagtgtgggt gtctattaca ataagtcgct
     4621 gttcaaagat gctggaatta cagaagatca attgccgacg ttagaagatc cttggacttg
     4681 gacggaattt caagcaattt gccaaaagct gactgataaa tacaaaacgc ctgcaattga
     4741 tatgcaaatg gcgtcgggag acgaaatgct gacctacgca tatacaccat ttatatggtc
     4801 gaatggcggc gatgtcgtta atgctgatgg aaccaaagcc gaagactatt ttaacggtaa
     4861 aaaatccgtt gaagcgttgg aatttattca agaattggtt gaaaaaggtt acaccacaat
     4921 cagtcctatt gaaaaaggat ttgaaactgg caaatatgcc atgatgctga gcggttcttg
     4981 gacaatggca gatttagagg aaaactatca agagattgat tatggtattt tgccttaccc
     5041 cgtttcagat gcaactgggg agttagtttc accaaccgga agctggcagt tagcaatgac
     5101 tgagaaaaca gagaaaaagg atgcttctgc ggcctttatt aagtttgcaa ccagtacaga
     5161 atctagtcgt attatgagtt tagggaacag tgttctacct atcagaaatt caacagttga
     5221 tttaattaaa gatgaagtgt cggaaggaat gcaggtatta attaagcaaa accaactttc
     5281 tggacatgcc cgcccagtgg ttgtagctta tccgcaagta tctagagcat tccaacaagc
     5341 agttcaagat attagctact tcgaggaaaa cccagatgta caaaaagtag cagatagtcg
     5401 cgctgctgaa atgcaacagg caattgatac ttcactaaaa tagaagtttc taaagggggc
     5461 caatcaagtg ttaaaaaaac cgacaatgaa agacaatttg ataggttacg gctttctagc
     5521 gccagctttg ctgctgctga cgatttttct gatcataccc gtaatcatgg taatttatta
     5581 tgcctttact gattattatt tgttaacgcc agatgctaga caatttatcg gcttagaaaa
     5641 ttttaagcga ctgttcgctg atccaatttt tgtaaaaagt atttggaaca cggctaaatt
     5701 tgttgtttgg attattccgg tccaaatagg ggcagcttta ggaatggcac ttattatcaa
     5761 caaaaatcgt aaaggaaata tcttttttaa agtagccttt tttgcgccag tcgtgatgtc
     5821 cttagtcgtt atttcgattt tatggttgta cttgttaaat cctaatgaag gtctggttaa
     5881 tacgctattt gcaaagattg gaattgcttc gcagcctttt ttgactagtc ccaaacaagc
     5941 aatgtatacg cttgttttcg tatcggcatg gcaaggtgca ggatatcaga tgctgctgtt
     6001 tttaggggga atgcaaaata ttccgcaaga cgtttatgag gcagccgaaa ttgatggttt
     6061 ttctaagttt cagcaatttc gctatatcac catgccatta ttaaagccca cggcgatttt
     6121 tattttactt accacattga tttcggcctt taaactaatc attcagccaa tggtaatgac
     6181 tcaaggtgga ccaatgaatt ctactatgac aatggtttat tacatttacc aaactggatt
     6241 tacagaccgt atggtaggct actccagctc cattgcgtta atctttacca ctatgattgg
     6301 tttaattaca attgctcaaa gaaaattggt aaaggaggat gatccagcat gaccaagaaa
     6361 tttggaccgc taatgatcgt agaatattgt ttgctgttcc ttttagcggc attattcatt
     6421 ttcccgatgc tgtggatggt agtttcctct atgaagcctg aagcagatgt ctatcaaaat
     6481 ttagcttcct tcaaagcttt tttacctagt ttgaatccag ctaattggtt taaaacttat
     6541 caagaggtta tttcccggtt cagtgtggga acttatttat taaacagtat tttttatggt
     6601 ttaacctttg cctgtgggtc aatcattgta aactctttgg cgggttttgc ctttgcgaag
     6661 gttaattttt caggcaagaa aattatcttt ggagctttgt tagctctgct gattgtcccg
     6721 atggagacgg ttttaattcc gcaatttacc atcgttaatt cactaggctt agtgaatact
     6781 cgcttggcag tgattttacc agcgatggcc agcgcgttta atatctatct gtttagaaat
     6841 ttctttatcg cgattccaga agaaatcatt gaatcagcga aattagatgg tgcaaatatt
     6901 gttaaaattt tctttcacat catgctgcca atgtctaaac cagccatagc cacagtaggt
     6961 gtcttatcct ttatctccag ctggaatgat tatatttggc cgttaatggt cttaactgac
     7021 agcagcaaat tttcaatgca agtggcaatt actacgatca atactacaca gccagtttat
     7081 atcaatcaag tgatggctgt tttaaccatt gcaacgattc cactgattat tgtttatatc
     7141 gttgcacaaa aatatattct gcagggactt ggcggttctg gaacgggtat aaaataggag
     7201 tgaatagtga atgttgcaaa aacttttaaa ggccaatgag tttattgaga aaaatgctca
     7261 aacagtcaat caagaatacc ggaataaatt tcatttgatg gctccgattg gctggatgaa
     7321 tgatccaaat ggttttgttt attatcaaga ggagtatcac ttgttttatc aatattatcc
     7381 ttacgacagc atctggggac caatgcattg gggccatgct aaaagcaagg atctaattca
     7441 ctgggagcat ttgccagtag cactggcacc aggtgaaagc tatgacaagg aaggctgttt
     7501 ttccggcagt gccatagaaa aggatggcaa gctgtatttg atttatacag gacacaatgt
     7561 tgtggaaggg caagttcgac aagttcagtg tttggcagtt tcagaagatg gcattcactt
     7621 tgaaaaatat gccggaaatc caatcatcgc agaagatcac ttagcttctg ttgcaacgac
     7681 cgaagatttc cgcgatccca aagtgtttca gcgaaaagaa gactatttta ctgtagtcgc
     7741 tactaaaact gcagatgctc gtggacaaat tgtgatgttc cattccaaag atttactaac
     7801 ttgggagttt tattccgtat tgctggaggg aactccagaa caaggcattg tatgggaatg
     7861 cccagacttg tttgaactag atggcaaaga agtcttgatt ctttctccta ttcaaatgac
     7921 tccacaaggc aatgcttacc aaaatacgaa ctcaactgtt gctttcatcg gtactgtcga
     7981 ttggcaaaca ggcaaatttc tagtagagaa ttttcatgaa atcgatggcg gtttagattt
     8041 ttatgcaccc cagacctgtg aaaacgaagc aggccaaaga ataatgattg cttggatgca
     8101 aatgtggcag cgtaaaatac ctacgaatga tctgggccat ggttggtcag gttccatgac
     8161 cttgcctaga gagctgaggg tggctgataa tcaattgttg caacggccag tttcatcaat
     8221 ttatcaagta attgatccgc aggaaaggat tgaatgggcg aagactgaag agaatcgctt
     8281 cttactgaag gacttagtat atgaccagca ctatttacgc ttggaaatca atttaaaaca
     8341 ggcaacgaaa ctagaacttc actatgcgaa gggacccgac catacattac tgcttaacta
     8401 tgatgttgaa cgggagtgct ttactgcttc cagggaacac atgccgtatg atttatcagg
     8461 agctgaaaag gaagtgttga aaaagcgcag tgtgacgatt cctttggaaa ataattgtct
     8521 aaccatcgaa attttccgtg atacttcagc tattgagctt tttctaaatg atcgtctgac
     8581 tatgagtaca actttttatg agacagaaaa aggacaggat tttcttttgc tggcagacag
     8641 tgaagtaacc ttttcattgg aaagcggctt aattaatcta tagaagggag agctcagtga
     8701 tgatttatgg ttcaatcgaa gcaggcggca caaaatttgt gtgtgccatt agcgatgaag
     8761 aaatgacgat caaggaaaga gtgagctttc cgacaacgac acctgaggaa acaatacctt
     8821 tagtcattga cttcttcaaa caataccaag cagatttagc agggattggg attggctcat
     8881 ttgggcctat cgatatccat cgcgattccg ccacttatgg gtacattacc tcgaccccga
     8941 aagtggcatg gcaaaatttt gatttcatcg gtaccatgaa aaaagaattt ccgatcccga
     9001 tttcttggac aacagatgtc aatgcggctg cctatggtga gtatgtcttc ggcagtggca
     9061 aaggattgag cagtgtcgtt tactatacga tcggtacggg tgttggcggc ggtgccttac
     9121 aagaagggcg ctttatcgaa gggtttagtc atccagaaat ggggcatatg ctcgtcgtcc
     9181 ctcatccaaa agatgacttt gctggcagct gtccatttca tggcaactgt ttagaaggga
     9241 tggccgctgg acccgccatc gaaaaacgct tagggaaaaa aggacaagag gttgcagaag
     9301 atgatcctta ttgggaaatc gaagcctcct atattgctca atgtgcctac aatacaacct
     9361 tgatgttttc tccagatgtg atcatttttg gcggtggtgt gatgaaacaa cgccatatgc
     9421 tgcaaaacgt ccacgacgca tttgcaaaat tggtcaatgg gtatgtcgaa acacctgagt
     9481 taagcaaata tatcgtgacc ccagcattag aagacaacgc tggaacgctc ggttgtttgg
     9541 cattggctcg agaagcggtc ttacattcat aaacgaaaaa aggctcttcg acatttagtg
     9601 ttggtagaga aagatacaac tgaaaattta gtcataacca gttaggcaga gtgcttaact
     9661 ggtttttgtt ttacttggaa gatcaagcct tgaatgagat aagttcttgc tcgaaagtta
     9721 tggaaatttc gatagccgta ggctacttgt attgtgcaat agttttttac aaaaaaaagg
     9781 gggtgcggat attttttttg gaccttttta acaaatatat ctttgcttct tccgatattg
     9841 aagagggctt agccttccta aagataactt aattcgttga ttattatacc aatgaatata
     9901 atcatccaat ttgtttataa actgattgat tgttgtattc ttccagtcac gttgataaaa
     9961 catctcgttt tttaatcgtc caaagaaacc ttcgcacgct gaattatctg gtgaataact
    10021 ctttttagac atagagtgaa gcaagttggc tttgttccaa tagtccaact aacaatagca
    10081 ccatcgtaac aatcgacaag tggtgataag tagattttcc ctgcgagaat tctaaattca
    10141 gtaatatctg ttaaccattt ttcatttggc ttctttgctt taaaattccg atttaataaa
    10201 ttggggtgtg caggagaaat ttccccagca tacgaagaat acttttttcg tctagaaaat
    10261 ttaacaaata gattttcctc agtcatcaat ctacgtacaa ctttttcaga aagcttttta
    10321 cccatatttt ttaaagcttg gtgaattcta cggtaaccat acgcacagaa gttatgattg
    10381 aaaatcgtga taattaattt gacgttcttt gtaatactta tctggtttct caagtgcttg
    10441 tttttgataa aaatagctgc ttttaggaaa ctggagctgt tgaagaagct ctttcaaggt
    10501 gaactgattt cgtaaggcat caatcaatat cgttttttct tgatttgata gacaaagaag
    10561 attgacgcct ttttcttttt ttagcagttc agccgctcct tcgagtaatg ctttttcgag
    10621 ctgtaattgg tgtacttgtt tttgtaagtc ttctacttcc tttaaaagta gctctttttg
    10681 tttttcctga ttttttaaag tcatacacaa tggaaaatcc tttccaagaa ccgtgttttt
    10741 ccattgatat agagtaactc tactaattcc tccagattcg gctaaatttt tcctattagt
    10801 ttgcggttta tagaattttt tcaacacagc ttctttttga tcttgtgtta actttaccgc
    10861 actttttcgg agttttctag ctcctggtgc aagttcttca caccgctgcc gcaaggactc
    10921 tctattagga taaccaagca tgcgaatggt tcgtgcataa cattgaccat attcaaaata
    10981 atgattcacc gctattcgtt tttgttcttc agaatacttt gatttttttc ggtgctcctg
    11041 atggagctct ccggattcca aatactcttt ataccatttc cgtagtgcac caatcgacgg
    11101 ataccctaat tctcgaatgg ttgcagcata agagcaatcg tattttaaaa ataactgaat
    11161 tgcccttaca cgctctttgt gggaaaacac acggacattc ctcctaagtt tattttttcg
    11221 tccaggatta tgtccgcacc cccttgcttt ctgatgactt attctggttc tttgagtgtc
    11281 aatgcataga tgtgatgtag ctagttagaa aaaaattttg aatactcttt ttttctttca
    11341 gactcctttt taagtaagat tttgaagtgt gagttacggg gtcagaaact taaaagtttt
    11401 tgatccttta ttttcaagtc tgatttggca gcttttcggc agctcattta tttatggtca
    11461 gaaatagatg ctgaaatttt aatctattag caaatagtcc agaacgtatg aagaggagtc
    11521 ggatatcatt tgtcattaac accataaata tttataaaat tcgtgttcac ctacaattaa
    11581 atttaatata taatattcgt tgtaagggct tataattttt tgttaatgaa caagatagga
    11641 agaaacattt aatggacagt tttcagagat tgtcactagt aaatcaattt gagttattgg
    11701 ctaaatttga ggaccaaaac agatcttatt atgaaagaaa aatcgaaata ttgagagaag
    11761 gttacgagta tcattatgat gatgaaattt ggagtgatct ttctgagcca tttccgaaag
    11821 aagattctcg atttgtatta gatgtattga acatgtatcg agatatcaat tttagtaaat
    11881 caaagctaaa cttagatgaa aaccaaatta ctaattcata ctatactcat ttcggttctg
    11941 ttgcaaagtt ttccaaaaaa tctattttag tgtaaaattg agaaaaaaga cagagaggac
    12001 agagtaatga atcattttaa aggcaaacaa ttcaaaaaag acgtcattat tgtcgctgtt
    12061 ggttactacc tgcgttacaa tctaagctat cgtgaagttc aggaattgtg atatgatcgt
    12121 ggaataaatg tttgtcatac tacgatttat cgttgggtac aagagtacag caaagtcctc
    12181 tattatcttt ggaagaagaa aaatagacaa tccttctatt catggaaaat ggacgaaacc
    12241 tatatcaaaa ttaagggacg ttggcattat ctttatcgtg caattgatgc ggacggctta
    12301 accttagata tctggttacg aaa
//
LOCUS       DACDLM010000079        12321 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.081, whole genome shotgun sequence.
ACCESSION   DACDLM010000079 DACDLM010000000
VERSION     DACDLM010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.081"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(178..735)
                     /gene="frr"
                     /locus_tag="IV356_002350"
     CDS             complement(178..735)
                     /gene="frr"
                     /locus_tag="IV356_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HAP9016002.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(738..1460)
                     /locus_tag="IV356_002351"
     CDS             complement(738..1460)
                     /locus_tag="IV356_002351"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010761216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HAP9016003.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1596..2477)
                     /locus_tag="IV356_002352"
     CDS             complement(1596..2477)
                     /locus_tag="IV356_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HAP9016004.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2576..3358)
                     /gene="rpsB"
                     /locus_tag="IV356_002353"
     CDS             complement(2576..3358)
                     /gene="rpsB"
                     /locus_tag="IV356_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HAP9016005.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3717..4196
                     /locus_tag="IV356_002354"
     CDS             3717..4196
                     /locus_tag="IV356_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HAP9016006.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4413..5504
                     /gene="phnW"
                     /locus_tag="IV356_002355"
     CDS             4413..5504
                     /gene="phnW"
                     /locus_tag="IV356_002355"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HAP9016007.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5497..5625
                     /locus_tag="IV356_002356"
     CDS             5497..5625
                     /locus_tag="IV356_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HAP9016008.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            5629..6174
                     /locus_tag="IV356_002357"
     CDS             5629..6174
                     /locus_tag="IV356_002357"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HAP9016009.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6628..8319)
                     /locus_tag="IV356_002358"
     CDS             complement(6628..8319)
                     /locus_tag="IV356_002358"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HAP9016010.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(8739..9686)
                     /gene="arcC"
                     /locus_tag="IV356_002359"
     CDS             complement(8739..9686)
                     /gene="arcC"
                     /locus_tag="IV356_002359"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HAP9016011.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(9801..10820)
                     /gene="argF"
                     /locus_tag="IV356_002360"
     CDS             complement(9801..10820)
                     /gene="argF"
                     /locus_tag="IV356_002360"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HAP9016012.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(10911..12140)
                     /gene="arcA"
                     /locus_tag="IV356_002361"
     CDS             complement(10911..12140)
                     /gene="arcA"
                     /locus_tag="IV356_002361"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HAP9016013.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         3380 a         2545 c         2212 g         4184 t
ORIGIN      
        1 ttaaaagatt cccactatct taagtattat agcaatatct aactgttttt cctatgaaat
       61 cattgttttt ttatttaaaa actgaataat tttttctttt tttaattttt aaataaaaga
      121 aatataaata aaaacagagg aagcggaatg atccgcccct ctgtttttat gattttatta
      181 aacttccaat aattcttttt ctttatcagc agcgatctta tctacttctt tgatgctgtt
      241 atctgtcaat gtttgtacgt ctttttctaa tccgcgcaaa tcatcttcgg taatatcacc
      301 atttttttgt tgttttttat attcatcgat cgcatcacga cggatgttac gaatcgcgat
      361 ttttgcattt tctgcttctt ttttcacatc tttagctaat tcttttctgc gttcttctgt
      421 cagttgcggg ataactaagc gaatgacatt tccatcattg gttggactga ttccgatatc
      481 acttgccata atagcttttt caacatcttg aagaatgctc ttgtcaaaag gtgtgatcat
      541 taaaacacgt gcttctggaa tttggattga tgccatttgg ttcaatggtg ttggcgcacc
      601 gtagtagttc acagtaatac ggtccaaaag gctagcgttc gcacggcctg cgcggatttg
      661 cccaagttca cgttgaagat tttgtgctgc ttttttcatt ttttcttttg cttctgtcat
      721 aattgcatct gccattttta tttccccctt acagttgttc cgatattttc gcctaagatt
      781 gcacggcgaa tatttccgtg ttcatttaaa ttgaagacaa gcagtggaat atcattatcc
      841 atgcttagtg aacttgcagt tgaatccatg acttgtaatc ctttggcaat aacttccaga
      901 tgagtcagtt cttcaaattt tactgcattt gcatctactt tcggatcagc agaataaaca
      961 ccgtctacat tgtttttagc catcaggata acatctgcgc cgatttctgc cgcgcgtaat
     1021 gctgctgttg tgtctgtcga gaagtacggg ttgccggtac cgcctgcaaa gataacgatc
     1081 cgtccttttt ctaaatgacg ttctgcttta cggcgaatat atggctctgc gatttgacgc
     1141 atttcaatcg aagtttgcac gcgtgtcggt acacccacgt tttccaacgt atcctgtaaa
     1201 gctaaggcat tcataactgt agctaacata cccatgtaat cagcttgagc acgttccatg
     1261 cccatttgtg ctccgatttg tccgcgccag atatttccgc cgcccacaac gattgccatt
     1321 tcaacgccca gctcgtgaac ttctttgatt tcttggatga tttctttgat tactggtggt
     1381 ttgattccaa atcctgcgtc cccagctaaa gcttctccac tcaattttaa gactacacgc
     1441 tgatatttcg gtgtgaccat gttcattcct ccaatatttt ctattgccat tttaccatac
     1501 ttagatgatt tcgacactct aagactggtt tttcttgttt tgcttaaaaa aagggagcgc
     1561 acaaaccgtg cgttcccgtc tgttattcaa cagaattatt ttttcacttg gctcataact
     1621 tcttctacaa agttatcttc gcgtttttcg ataccttcgc caacttcgaa acgtacgaat
     1681 gttttaacag ttgcgccttt tgatgcaacg tatttttcaa cagtcatatc aggatcttta
     1741 acgaatggtt ggtccaccaa agcgatttct gctttgaatt tcttcaagcg tccttctacc
     1801 attttttcaa cgatattcgc tggtttgcct tcgttcaatg cttgttctgt aagaacagtt
     1861 ttttcatgtt ctaattcagc ttctggaatt tgtgattcgt ttacataacg aggattgata
     1921 gctgctacgt gcatagctac gtctcttgca actgtttcgt cagttgttcc atctagaaca
     1981 gtcaatacgg caatacgtcc gcccatatgc aagtatccac caaatgcagc attgtcgtct
     2041 ttttctacaa cttcaaagcg acggaagctg attttttctc cgataacttg agttgcttcg
     2101 atcaagtcag attcaattgt acctttatct gttttgattt tcattgcagc ttccatgtct
     2161 gctggtttgt tttcagcaac aagttctgca atttctttta ctaaatcttg gaacatttcg
     2221 tttttagaaa caaagtctgt ttctgagttt acttcaacga ttgctgcagt gttacctttc
     2281 acagcaactg aagccaatcc ttcagctgca atgcggtcat ttttcttcgc agcctttgcc
     2341 attccttttt cacgtaaaag atcaactgct ttttccatgt cgccttctac ttcaactaat
     2401 gcttttttcg catccatcat tcctacgcca gtcatttcgc gtagttcttt taccatttta
     2461 gctgtaacgt ctgccatgtt taactcctcc tgtgtgtttt tctttttaaa aaaagctgct
     2521 tcaaaggaga gtgaggcttg tcgcccagcc tttgaaacag ctccatcatt caaaattatt
     2581 ctgctgaaga attgtcgcct tcaacaacat ctacgatttc ttcgattgat gttgctgtgt
     2641 tttcttctgt gaaatcttct tcaactactt gatcttcacc ttggtttcct tcgatgaaag
     2701 catcagccat ttttgaagta atcaatttaa cggcacgaat tgcatcgtcg tttgaaggga
     2761 ttactacgtc gatttcatct ggatcgcagt ttgtatcaac catagctacg attgggatat
     2821 ttaatttgtg tgcttcttga acagcaatac gttctttacg tgggtcaacg atgtacatta
     2881 catctgggat tcttggcata tcagcgatac cgcctaagaa tttttcaaga cgttcacgtt
     2941 ctttgttcaa accagcaact tcttttttag gtagaacttc aaaagttcca tcttcttcca
     3001 ttgcattgat ttgtttcaaa cggctgatac gtttttggat agtatcccag tttgtcaatg
     3061 ttccgcctaa ccaacgatgg ttaacgaagt attgtcctgc acgagttgct tcttctttga
     3121 ttgcttcttg tgcttgtttt tttgtaccta cgaataatgc tacgccgcct tcttcagcaa
     3181 cgctcttcat gtaatcataa gctgcatcta ctaatttaac tgttttttgc aagtcaatga
     3241 tgtagattcc gtttctttct gtgaagatat atttcttcat ttttggattc cagcgacgag
     3301 tttggtgacc aaagtgtacg ccggcttcta gtaattgttt catagaaatt actgccatgt
     3361 ttgtttcctc cgatttggtt ttatttttcc tcttcttatc ttctaccttg ccggcaaact
     3421 ttttcaagca cctaccgaca atccaataag aatgtggatt tgctgatgca taaagcaccc
     3481 tcagctatta tacagacaaa agatccgtat cgcaagagca aatatacttt tctgctcaac
     3541 attcaatagt ttacctgaaa gataaaaaga attcaagaaa aacagtagat ttctctttgt
     3601 ttctttatta tcctttttcc ataaaataat tttaggtata aaagacgaat attattgggc
     3661 aatccttctt ttttttgtta tgatacatgt gaaatctttc gtaaaggaga aagaaaatgc
     3721 gcaaagctca aagacatttg ctgattaaac aagtcattga agaattcccg atccgtacgc
     3781 aagaagaact attaaacaaa cttgggcatt atggcgttac cgccacgcag gcaacgattt
     3841 ctcgagatat ccgtgatcta aaaatcgtga aggcacctga tgaaaatggc gtttcccgct
     3901 tcgtattgtt tcgcgaaaaa ggaactcctg agactaggac tgaggaagag gatcggctgg
     3961 ttcaaatgat tgaagacatt gtattgaaag tcgaacgagt ccactttttg acgatcgtca
     4021 ataccttgcc agacaatgct catttatttg catctgtttt agatgagatc aaacctccct
     4081 ctattgtcag tacaattgct ggattcgata cgatcatggt catctcggaa aatgaggagg
     4141 acgcaaaacg agtagaagaa tttcttcacc atccaactga agtatcactt ttttaatcag
     4201 agcacgtatt cctaatatgg aatgcgtgtt tttttatttt caatattttc cttattgaat
     4261 aaacctttac actctttaca aaaatacatc attttttatt caaatttttc aacaccttga
     4321 ttgaatcaca ataatcatca tttatattgg atgttaacaa gagcagcttc ttgctctttg
     4381 tgtatttcaa aaaagaaatg aaaggaaatc atatgtataa attattaact tctggaccat
     4441 tgacgacttc tgaaacagtg aaaaatgcta tgctgatcga tcattgtact tgggatcaag
     4501 aatacaaaga aattacacaa tggataagaa aaaaattatt ggatcttgct caagtatcgg
     4561 aaggaatata cacaacggtc ttaatgcaag gtagcagctc cttcggggta gaatcggtat
     4621 taagttctgt gatcaggcca gaagatactg tactgatttg ttcaaacggc gcatatagac
     4681 aacgaatgat caacatgtgc gaatgtctga aactgaacta taccgtttat gaggtatcgg
     4741 aacatcaaat cctccaagct catgtgatta cacagctgat tgaagagaat ccgtctatct
     4801 ccgcactagc aatggtccat agcgagacta cttccggtat tttgaataat ttggaagaga
     4861 ttgctgctgt cacacaagaa agagatcttt tgtttatagt ggacgcgatg tcaagctttg
     4921 gtgggatacc gatttgtgta gccgaactag ggattgattt tttgatttcc agctcaaaca
     4981 aatgtattca aggtgttcca ggcttttctt ttgtacttgc taataaagcg gaactggaaa
     5041 aacgaaaaaa tgttagccga agtttgtcac ttgatctata tgaccagtac cgcgtgatgg
     5101 aaaacgagaa tggcaaatgg cgtttcactt cccctaccca tacggttttg gcttttcaac
     5161 aagcgctgaa ggaactagag gcagaaggag gaatcgaaac tcgatattca cgttatctcg
     5221 ccaataatca tgtgctacga caaaaaatga cagagatggg gttccagcct ttcattcaag
     5281 aatatcaggg gccattcatc acctcttttc tttaccctaa ggactggcga tttgatttta
     5341 atcattttta tcagtattta aagcaaaatg gatttgtgat ctatcccggg aaaatcagcg
     5401 atcatgaatg ttttcgtatc ggaaatattg gcgagatcta tccggaagat attttggaac
     5461 tgacagcaat tatcaaagac tataaggaga acgttaatga ttaaaactgt aatttttgat
     5521 tgggcaggaa caactgtgga ctttggctgt atggctcctg tccacgcttt tagaaatgct
     5581 tttctagaaa aaggaatcca actgactgac aaagaaatcc gctaaccgat gggaaaatta
     5641 aaatgggatc atatccaaca gcttctttcc ctcccttctg tcaaaaaaca atggatagct
     5701 atttatggac aactacctca ggaaaaagag gtggaggaat tgtatcaaca atttgaacat
     5761 tatctgttta aagatttggt caagcattct accttgaaac ccgacacatt ggaaacgatc
     5821 gaacggttga gaaacgctgg gatcaatatt ggttccacga atggatttaa tgctcctatg
     5881 atgacaatcg tagcagaaac cgcaaaaaaa gaaaggtatt caccagactt catggcaact
     5941 tttgaagacg tcgaagggta tggtcgaccg tttccttata tgatccataa aaacatgcag
     6001 tacttcaaaa acaagtcggt tgatgaagta atcaaagtcg gagatacggt ctcagatatc
     6061 caggaaggga aaaatgccgg agtgttgaca gtaggtgtaa ttgaaggtag ttcgctaatg
     6121 gggatttctt atgatgagta ccaaaaatta gagatgggga aaaagatcgt ttaaaacagt
     6181 ctgttgctct tagattccaa caagccggcg ctgatatttg tgtaaacaat ttaaaagagt
     6241 taacagaata cattttgtac gctgacaaga atccagaatg acttttatac aaaataagag
     6301 gttgtgaaaa agctgtcctg tatcaagtaa taaaaacagc caagcaaaaa tagctcctca
     6361 tatttttcgt ttggttaggc ttattaccgc agatgcaagc ttttgaacac cgtttattcg
     6421 aaaaaaaaaa gggagctgtg acacgacttt tgtcacagtc cccttatttg caaacaaaca
     6481 gtgtttaaga gacaacctct ccactaaacg gtgttcattc agctgactct cggtatttgc
     6541 tcaaaaaacg ataaaatttg aaaagctatt ttctcttttg tttctctaat actcggatca
     6601 gaacgctgat ttcacattct ctttttctta catcttatct ggtgcatgaa gtcctagcaa
     6661 acgaaggtct tctttcaata atacagtcac tgcataaact agagctaagc gtgcttcttt
     6721 ttgttcatca tcagctaaaa tcttcgtatg agcatagtat ttgttgaatg cttgtgctaa
     6781 tttgattgca tgtttcgcaa tcactgacgg ttcgtatttt tccccagcag acaagaccgt
     6841 ttcagggtat ttttgaacta atttaaccac ttcccagctg gtatcgtcat tcaatgcata
     6901 gtctgctgtt tctgaaggga caaatcctgc tttttccaac aggctgactg cacgagcatg
     6961 tgtatattgc acataaggtc cagtttctcc ttcaaatcga acaacttctt ccaggttaaa
     7021 gtcaaatgta ttcagtcgat cgtttttcaa atcgtggaaa atgactgccc caaccccaac
     7081 ttgtttagct acagcatctt tgttttccaa atcagggttt ttctcgctga tttgttcttt
     7141 agcagattgg attgcttcat ttaatacttc ttctaataag acgatctttc ctttacgagt
     7201 tgataatttt ttaccacctt gcgtgatcaa accaaatgga atatggtgca tgtcgtcaga
     7261 ccagtcaaag cccatttcct tcaagacagc tttcaactgt ttaaaatgat agctttgttc
     7321 attccctact acatatagag attgtttgaa gtcgtaagta cgtttacggt acaatgcagc
     7381 agctaagtca cgtgtaatgt atagtgtcgc accgtctgac ttcttaatca acgctggatt
     7441 caggtcataa gcagataggt caacgatctc tgcaccttta tcctcgttca gcaaatgttt
     7501 ttcttctaaa agtttgacga tttcatccat cttgtcattg tagaaagctt caccgttcaa
     7561 cgaatcgaaa cgtacttcca gcagatcata gattttattg aattctttca tcgattcatc
     7621 acggaaccat tgccataatt gaatagcctc tttatcgcct tcttccagac gtttgaacca
     7681 agcacgagct tcttcattta attctggttc tgtttcagct acttcatgga attggacgta
     7741 taaacgaagc aattcattga ttggttctgc tttaacagct tcttctgtac cccatttttt
     7801 gtaagcgacg atcagttttc caaactgtgt tccccagtca cctaaatggt tgatgcggat
     7861 tggctgataa ccgatttttt ccataatgaa accgatcgaa ttaccgataa ctgtcgaacg
     7921 caaatgtccc attgagattg gtttggcaat attaggagaa gacatgtcga ttggtactgt
     7981 tccttgattc ccgatgttgc tatccccata atgttctttt tctttcacta cggtttgcaa
     8041 aacttttttg ctgataagtt ctttattcat gaaaaagttc aagtaaggtc cgacaacttc
     8101 gattttttca aagttggcag aatcgatttt ttctgctaaa tctgcagcga tttgctgtgg
     8161 cgcttttcgg taaacttttg ctaatgaaaa ggctggaaat gcaacatctc cgtgttcagc
     8221 tgattttgga ttttctagta attgctcgac ttgttccagt gttaaatcat ctttgacagc
     8281 gtcatagaca gcttttgcga caagatcttt attattcatc tttattcctc ctaaagtgtt
     8341 cccttgattg ttaaacaaaa aaaatctcta gcgacggcat acttagtatg ccatcactag
     8401 agacgagatt tcccgcggta ccactccaat tgtcctaaaa aaggaccagc tccatctgat
     8461 atcggtagac gaccgtctgt ttaaaacaga attctccaag tgcgcttcgt tgtatcttct
     8521 tcattcggct tccaccactt ccgaattcgc tagccaagaa tgatacaagt actctcttgt
     8581 tcaacaaatc ttagtcttat taaactttct tgaattatat cagaaaaaaa aacgaaaggc
     8641 tagtcgtttc ataaaaaaaa aatccagatg gcctaaagga gaagaaatac cacctggata
     8701 gctataaatc atttcgtaaa tacgaaagac ttaacaaatt aatcagctac gataatcgtt
     8761 ccttcttcag aagctaaaag attctcgata ttttctaaag aagtgatgat tgccttagcg
     8821 tttggttttg cttcaacaaa tgcaatagct gcttctactt tcggaagcat gcttcctgga
     8881 gcgaattgct tttcatcaat gtattgtttc atttctgaaa cagtaacagt ttctaatttc
     8941 ttttgatctg gtttttggta attgacatac acattgtcta ctcctgtcaa tacgatcagc
     9001 aaatccgcat cgatgatttc ggctaatttt tctgaagcaa aatctttatc gattacggct
     9061 tctcgtcctt ctaatccagt agctgtttct acaacaggaa tcccaccgcc accaacagag
     9121 actgtgataa ctccttgatc gaccagcgtt tcgatgacac gtgcttcttt aatcgagatg
     9181 ggtttagggg aagcgactac ttttctccat ccacgtccag catcttcttt gaatgtcaca
     9241 gtggagtcag cattcatttg ttctttggct tcttcttccg tgtagaatgg accgactggt
     9301 ttacttggat ttttgaatga aggatcattt tcatccacaa taacttgagt gactaaagaa
     9361 accacatctt tatcgatccc tttttccttc agtacttcgc ccatggcgtt ttgtaaccag
     9421 taaccgatag atccttctgt cattgcaaca catgtatcta aaggcattgc cggtgttttc
     9481 tcagaatcag cagcttgctg ctgaatcaat aggttaccga cttgcggacc atttccgtgg
     9541 gagatgatca attcatctcc ttgttcgata aatttcacta aatactttgc tgtttccatt
     9601 aacgcttctt gttgggcttt tgcacttgca tccgtagaca agatggcatt gccccctaaa
     9661 gcgacaacta cttttcgttt ggccatttca ttcgtccttt cttcagttct accgaatttt
     9721 ctagataaca aaacgagcca gcgttttgtg attttccctc aatgctgact cgttttttcg
     9781 tgagatgaat gtggttatgc ttaaacgcga gggataaaca agttacctaa tgttgctgcc
     9841 atgatcgctt tgattgagtg catacgattt tctgcttggt caaattgacg agcatatttg
     9901 ctgcggaaga cttcatctgt tacttccatt tcagtgatgc caaagcgttc tttcatttgt
     9961 tcaccgtaaa cagtgtttgt atcatggaaa gctggcaagc agtgcaagaa gatcaaacga
    10021 tctgtgttgt gtgttttttc taccatttcc atattgattt ggtaaggttt caacaatttg
    10081 atacgttctt cgaatttatc ttcttcaccc attgataccc atacatcaga ataaaggacg
    10141 tctgctccgt ctacaccttt atcaacatcg tcggtaatca tcaattgtgc accggatttt
    10201 tcagcaaagc cttctgccat tttgacgatt tcttcttcag gttgtaattc ttttggtgca
    10261 acgatacgca tattcgctcc taaaattgca cctgtgacta ataaagagtt agccatattg
    10321 tttcgaccat ctccgcagta agcaacagtg ataccttcta ctgttccaaa gttttcttgg
    10381 atagttaaaa agtcagcgat catttgtgtt ggatgccatt catcagtcaa gccattccaa
    10441 actggaacac cagagaattc tgctagttcc tctaccattt tttgactgaa tccacggaat
    10501 tcgattccgt caaacatacg tcctagtact ttagctgtat cttctgtgga ttctttttta
    10561 cctaattgga tatcatttgc acctagatat tcaggatgtg cacctagatc gatcgctgca
    10621 gtagtaaatg cagaacgagt acgtgtagat gttttttcaa ataaaagcgc aatatttttt
    10681 ccttctagat agtgatgtgg gataccacgt tttttcaagt ctttcaagtg ttctgaaaaa
    10741 tcgatcaaat attgtaattc ttcttttgta aagtcttttt ctgctaataa gcttcttcct
    10801 tggaatactg attctttcat attaaacatt ctcctttaga ttgtttttat ttaagattaa
    10861 agaggaaatc ccgacggcag ctgacagtaa gactgccgtc aggaaacaaa ttacttcaag
    10921 tcttcacgga caagtggttg gctcatgcag cgtggaccac cacgacctcg tgacaattca
    10981 cttgaattga tttctaacac tttgatgcca tagctacgaa gcaattcgtt cgatacataa
    11041 tttcggttat aagtgactac aacacctgga gcgattgcca atgtgtttga tccatcattc
    11101 cattgttctc gaggtgcaac gatctcatct ccattaccag ttgggatcag tacaagatca
    11161 tctaatccaa gagcagcttt catcgtttcg tgtaagttat ctgaatgagt aatcttgata
    11221 tcatcaccat ctggttcgat tgtaaagaca tccatcttac cgtctttact ttgaattgct
    11281 ggatggatag tgaatttatc gtgatctacc attgtaaata cggtatccaa atgcatcatt
    11341 gcacggttgt tcggaatttt gattgccaac actttttcaa atcctgaatt ttttgcgaat
    11401 aggtggcgtg ctaatttttc taaagctttc gcattagttc gttgagaaat cccaacagct
    11461 actactttat cgcttaagat caattcgtct ccgccttcga tatgatctgg attttcacga
    11521 tccaaccata cttcgattcc tttatttgca aatcttggat gatgtttcaa aatatattct
    11581 gtaaacatcg attcacgacg acgtgcttca aaagtcatct tattgactgt catcccattt
    11641 cccattgatg cggaagggtc gcgtgtaaag tacaagtttg gcattgggtc catgtaaaat
    11701 ggatagtcat cgtctgctga cagatcatat agactgctag aacgtacttc gatatctttt
    11761 gtacgaaccc cagccatgat tttatctacc atttcttgcg tttccattga tagaaggaac
    11821 tcatgaagac cctctcttac agcattcgat gcaatatgag attcatccaa cattttattc
    11881 aagaattgtt ctttgacatt gcctgcgtca atcgcttctg ccgctaattt ttccaagtaa
    11941 agagtctcga cgccttcatt ttgcaatgtc ttcgcaaagt tgtcatgttc ttcttgagca
    12001 atcggaagat atggaatatc atcgaacaac agacgatcca taatatctgg tgtcaaattt
    12061 tccacttctt gtccaggccg tttcagtaaa actgtcttta atttccctat ttcagagaaa
    12121 acgtgaatag gtttatccat gttgtgttgc ctccttcttt ttgattacat gtataggata
    12181 tcctcctttt gtaatcactt tcataatttt gtctcattca aaatgagaca ttcctcacat
    12241 taatattcga taattaaata attaaacgtt tttctatttt taagcgtaat ttattcattt
    12301 tttattctgt atacactttc a
//
LOCUS       DACDLM010000080        12190 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.082, whole genome shotgun sequence.
ACCESSION   DACDLM010000080 DACDLM010000000
VERSION     DACDLM010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12190
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.082"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..395)
                     /locus_tag="IV356_002362"
     CDS             complement(<1..395)
                     /locus_tag="IV356_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP9016014.1"
                     /translation="MQGVIAMMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFE
                     FIYPIVEATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGYS
                     FEEKIPPFSTFGKNYVRRFRETTVFEDIFA"
     gene            1029..2000
                     /locus_tag="IV356_002363"
     CDS             1029..2000
                     /locus_tag="IV356_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HAP9016015.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
     gene            complement(2078..2314)
                     /locus_tag="IV356_002364"
     CDS             complement(2078..2314)
                     /locus_tag="IV356_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP9016016.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(2283..2414)
                     /locus_tag="IV356_002365"
     CDS             complement(2283..2414)
                     /locus_tag="IV356_002365"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP9016017.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            complement(2490..2873)
                     /locus_tag="IV356_002366"
     CDS             complement(2490..2873)
                     /locus_tag="IV356_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAP9016018.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            complement(2906..3691)
                     /locus_tag="IV356_002367"
     CDS             complement(2906..3691)
                     /locus_tag="IV356_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HAP9016019.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            3869..4969
                     /locus_tag="IV356_002368"
     CDS             3869..4969
                     /locus_tag="IV356_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP9016020.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            4959..5783
                     /locus_tag="IV356_002369"
     CDS             4959..5783
                     /locus_tag="IV356_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphatase"
                     /protein_id="HAP9016021.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            5789..6595
                     /locus_tag="IV356_002370"
     CDS             5789..6595
                     /locus_tag="IV356_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP9016022.1"
                     /translation="MKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLANYS
                     DIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLAANF
                     AGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYPSMK
                     EVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALTSSN
                     VNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            6592..7422
                     /locus_tag="IV356_002371"
     CDS             6592..7422
                     /locus_tag="IV356_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9016023.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            7429..8460
                     /locus_tag="IV356_002372"
     CDS             7429..8460
                     /locus_tag="IV356_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9016024.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(8567..9840)
                     /locus_tag="IV356_002373"
                     /pseudo
     CDS             complement(8567..9840)
                     /locus_tag="IV356_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            10117..10326
                     /locus_tag="IV356_002374"
     CDS             10117..10326
                     /locus_tag="IV356_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016025.1"
                     /translation="MDVLREYSSLFTEAYLLEQFGYKIPFADYQQGVGTAAELSFYEG
                     ISQAVGRPVDAEHFEQRISSTGKSE"
     gene            10376..11092
                     /locus_tag="IV356_002375"
     CDS             10376..11092
                     /locus_tag="IV356_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HAP9016026.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(10994..11514)
                     /locus_tag="IV356_002376"
                     /pseudo
     CDS             complement(10994..11514)
                     /locus_tag="IV356_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            11802..>12190
                     /locus_tag="IV356_002377"
     CDS             11802..>12190
                     /locus_tag="IV356_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP9016027.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLS"
BASE COUNT         3494 a         2279 c         2772 g         3645 t
ORIGIN      
        1 gcaaaaatat cctcaaacac cgtcgtttct ctaaatcggc gaacataatt ctttccaaaa
       61 gttgagaaag gggggatttt ctcctcgaag gagtagccta aaaaccagcg gtaagcgaca
      121 ttggtatcga cttccttaat ggtttgtcgc atggaacgga taccgaataa atactgaata
      181 aacaccaatt tgatcagaat cactggatcg atacttgggc gacctaaatc ggagtaagtg
      241 gcttcgacga ttggataaat aaattcaaaa tcaagcgcgg catcaatctt tcgaacgaga
      301 tgatcttgag gaactagatc atcaatcgta agcatcgcaa attgatttct accattcgta
      361 ttgtttttag acatcatagc tatcactcct tgcattcgtt ttcataaatc tattataaaa
      421 gaaaagactg tagacatcat ccataaaatg gactttgtct acagtctgga taacgtgatt
      481 ttttgctgta atgacaaggt tttagctgtt tcagatacca tgtatccaaa aatagtttat
      541 tgagaaaata ggagagtatt tgatactaac tagtaggaaa aaatgagata aaaagtaaat
      601 ggaatcattt aaggtaatct gaaataaaaa atatacagcc ctgtggtact ttacctacaa
      661 ggctgtatat attttttact ctcagcgttt ttgactccgt gtctgactcc gttttattga
      721 ttttgaatgt tattcaatga ccatttaaca ggtcaaattt gatgtttttg attccgtatg
      781 acgccgtttg atatctagtg atatagtgat ttgagtctac atcgaataag ggaataaacc
      841 aataaaaaat gatttagaat attaaaataa caaaaaagag gactacctgt attagtcctc
      901 ttttttgacc agattttgac cagtctattt tacatcctag tatatttata tgagctaatt
      961 ttatgattaa atggtaagtt tttccttgtg tgttttagtt taaactagtg tgtaattcaa
     1021 aaatctatat ggaaggaaca gtattaagaa tagaacaggg ttctctacat gatggtgctg
     1081 gtttacggac cgttgtttat ttaaagggct gcccattacg ctgtgcctgg tgttcgattc
     1141 ccgaatcaca aagcaagcag attgaaaaag gatttggcca gaccatgacc gctgaagagg
     1201 taatggatga gattgagaag gatgctgttt tttactttca ctcggatggc ggagtgacca
     1261 ttagcggagg cgaggcactg gttcaggcgg attttgctaa agaaattttg caaaaatcga
     1321 aatacattgg aatcaatacc gtactggaaa ccagcttttg tggtgcttat aatgaaatcc
     1381 aaaaggtagc tccctatgtg gatacattgt ttgtggatgt aaaaatgttt accagcaagc
     1441 tccacaaaca atggaccggc ttagataacc aacaaatttt gaagaatatt cgtcgctttt
     1501 taattgagta tcctaactgc gaagtgcgaa ttcgagttcc tgtggttcca ggtatcaata
     1561 tgaacctgac cgagctgctg acgattgctt gttttgtggc agatcttgat cggttcgtac
     1621 cgttagaatt actaccgtac cactgctatg gtatgcacgg ttaccaagca ttgggactgg
     1681 agtatccgtt ggcagacacg ccagcgcctt cacctaaaga aatgtttgca ttggcagatc
     1741 aactggctcg cacggttcct catttgctgg tcacagcttt aaccaaaaca tttatttatt
     1801 tattgaatcc aagctttatc ttatggataa atgaaagaca ctcactagct gcagccagct
     1861 caagaataga gcttttgctg aagtcagtga gtgtcttttt acgatgtttt ttcgaagtta
     1921 atttgtcgaa tgaacactgg ctcaatcggt acatcttcac tgtttgtcgg ctgagctgcg
     1981 atcgctgcta cgatttctaa cccttggtat acctgtccaa aaacagtata acgaccatcc
     2041 agctccggta gtcctccaag ctccaagtat gcttgcttta cattagcagg tcagcctgcg
     2101 cctttgtgtt ttgcacaata aaaaactggt tgccgttggt gtgggggccg tggtccccta
     2161 aggccaaggc gccattaaaa tgataaagtc cgcgatgcac ttcatcagcg aaaaagccct
     2221 catagctgga aacagcttca tcaccagaac catccaaagc gccaccttga ataacaaatt
     2281 ccttaatgac acgagccgaa aggtgtgttg tcataaacgc cttgctcagc tagggagcgc
     2341 cagttggcta cagccagggg agcttggtca ggaaataagc ggagacgaat ttcaccagca
     2401 tcggtgacca gcacacaaac ttcttcctgc tgcggttttt ctaattgaaa gagaggaagg
     2461 tttgcaactg aaacgccttg atcctgccat caaatatcga aaatccgcca ctcgaccttc
     2521 gcctgatcac caaggcgagc cattcccaat aaaacggtat aggcggtttc atccgcttga
     2581 aaggtcaatt gcagctgtcc tcgtaaatcg ttgtagtcat ctggggcggc tacttgataa
     2641 aaaagatgaa actgcgcatg caaatattcc aaaggctgat ctttaaaggc tgcaaaataa
     2701 gcctgaactt tttcccgctg caagctgtca gccaccaaaa aattttccag ttgttgtttt
     2761 ggaacggctg ctaacaagga tcggcaaacc gcctcaattt tcaacgcatc ccaatgtcgc
     2821 gcaattaaat aatggatggg tgcctcttga ttgtagtccc acaggttgct catttttttc
     2881 accactttct tctattatat aggaatcaca aaatcggcag cggcgtcagg cggcgttctt
     2941 ttccttgaat gactagcaac ttttctacct gacagtctgc caacagctga ctcatttttt
     3001 taaagcccag ctgataatct tcggcaacat gagcatccga gcctaaggta aagagctttc
     3061 cgccgacact ttgatacaaa ggaacggcat aacggtaaag gtcttcgttg ccgtatttca
     3121 agaagctctt ggcatttaac tccatcgcca attctcgttc aacaaccttt ttgaaaatcg
     3181 ttagcagctg agcctcaaaa tgctccgcga attcttccgc tgtgaaggtg aagcggcgta
     3241 atccataatc aaagtgagtc aaaatatctc cttctggaaa atccgtcaag acctgcaaca
     3301 tctgatcaaa atattccttg gtagtttgaa tgggatcttt ggttaaaacc acatcgtcca
     3361 tataatcaaa gcggccattt tgatgaatac ttaccagctt taaatcataa ggatgctgag
     3421 cgaggtaatc cacgatccgc tcttcttgtc ctggaacaac gccaatctcg atacctcgca
     3481 gaaatttggt ggaataggtt tcttttaaag agtccagttt gtttatatag gctggataat
     3541 ccggaatgtc atcttttccg gtagatggat tgtttaaatc aaagtgatcc gtagaaacga
     3601 aaaactccgg ctgataggct aaatagtttt caaatttttc ctctgaatca aaggaaaaat
     3661 acgtgtggag atgctgatca taatactgca tagggagcct ccttttttct actatcatac
     3721 cgcaaaagct ttagaaggtt aacgggaatt cgtcgaaatt tacaaaccat atacaacctt
     3781 tacattgttc atgaaacctt ttcaagaaac tgattctctc attacaaagc tttgttagaa
     3841 tggaattatc gaaaggggag aagaatgaat gaaaatgaat gaaaaaattc gtaacatgac
     3901 tatcggttta ttttgtgcag caacagtaag tatcctgctg acaggctgcg gctcaggtga
     3961 agcaacgaag caatcggctg cggcagacga ctctttagat acgattatag aaaaagccaa
     4021 ggaagaagga gagattgcca gcttgggaat gccggatact tgggcaaatt gggtaggcac
     4081 ttggaacgac cttgaaaaag aatacggctt aagtcacgtg gatacggata tgtccagtgc
     4141 agaagaattg gctaagtttg aatcagaagg aaaaaatgga accgccgata ttggtgatgt
     4201 cggtatcagc ttcggtccgt tggctgaaag caaagagtta accttacctt ataagaccaa
     4261 ctattgggag gaaattccgg attgggcaaa ggatgatgat ggggattggt tgttaagcta
     4321 tacgggaacc atttccttta tcaccgataa agagaatgtg aagcaagcac cgactagctg
     4381 gaaggagctg caagagggtg actatcaagt tagcgtgggg gatgtgacga ttgccaacca
     4441 agcacaattt gctgtattgg ctgcggcgat tgccaacgga ggtgacgaaa aggatattca
     4501 gccaggtctg aattactaca aaaaaatggc agaaaaaggc cgtttgtcca ccgttgatgc
     4561 cagcgtagca aatcttgaaa aaggtgaaat cgatgtggca gttgtttggg acttcaatgg
     4621 actaaattat cgtgaccaaa ttgactccga gcgttttgag gtaactgtgc caacagacgg
     4681 ctccatcatt agcgggtata caaccttaat caataaaaat gcccctcatc ccaatgcggc
     4741 aaagctagca cgggaatata ttttatctga tgaagggcaa atcaatttgg caaagggcta
     4801 tgcgcgacct attcgcaagg tagagctgcc taaagaagta gctgaaaaat tactgccgga
     4861 ggatgcttat gaagcggcgg tgccagttga agacaatgaa gcttggaaca agacctctgt
     4921 agagcttcca gagctttggc aggcggaggt actgacctat gcaaagtaga cttgacaaac
     4981 tgattgtagt tatactagac ggctgtcgct acgacacagc cgtcgcccag cttgggttca
     5041 tgaatcattt agttgagcac cagcaagcaa gcttattgaa ggtaaaaagt gagctgccca
     5101 gcaattcacg tccgttatac gaagtactga tgaccggcgt tccagcctat gaaaatggca
     5161 tctatagtaa ttaccatgct cagcgatcca aagagtggtc gctgtttgaa ttagttaagg
     5221 aagctggcgg aaaaacagga gccgccgctt accactggta cagcgagttg tacaatcaag
     5281 ccccctataa tcgtttggtt gatcgcatcc agcatcagga ggagcgactg attcagcatg
     5341 gcatctttta tagtgaggac acttaccctg attcgcattt atttgcggat gcccattatt
     5401 tagtgaatca gtatcagcca gactttttgg tcgtacattc gatgaatatt gatgatgtcg
     5461 gtcacaaatt taccgccgat tctcatgaat atgcagcagc ggttaatcag gcggacagat
     5521 tattggctat ttaccttcct gaatggctgc aaaaaggtta tcaagtcgtg gtgactgcgg
     5581 atcacgggat ggatgcgcac ggactgcatg gcggcagctt ggctgcacat cgtgaagttc
     5641 ctttttattt gatttcaaat aaacgccaaa agctgaagga acaaactgta ccacagctgc
     5701 tggcggctcc attgttttgc tggttattag gaattgcacc gtcagagaaa atgcaggaca
     5761 ttcaagaatt gatgagggga tgaaagagat gaaaaaacgc ttggttctgg ttcctgcctc
     5821 ctttatcttc tgtgcatttt tactgctgcc gctgcttttt atggttctgt gcagcttgca
     5881 cagtgattta actaaccagt ggacattggc caattacagt gatattttca gcaacaaata
     5941 ttacacacag gcctttgtta acagcgtact gattgctgtc agctccagtg tgattgggtt
     6001 aatcgggacg tttattttat gtttatgctt aatgaatcta tcgactaaat tgcaggagaa
     6061 aatcaccttt gtttccaatt tggcagctaa ttttgctggg attccgctgg cattctcttt
     6121 tattattttg ttggggaatg taggtgtgct gaaaatgatt ttgccatttc tagcggactt
     6181 caatttgtat tcttggtggg gattgaccat cacgtatacc tatttccaaa ttccgttagg
     6241 ggtcttgttt ttgtatccca gcatgaagga agtgaaaaag gaatggctgg agtccgcaca
     6301 attgctgggc gcttcatcag cgtatgcttg gttcaaggtg gctttgcctt ttttgcgacc
     6361 atcgattgcc agcacctttg tcatcttatt tgctaatggc atggggacct atgaaacagc
     6421 gtatgccctg accagcagta atgtaaatct tttaacgatt cgaattgcgg ctttagtgtc
     6481 gggagatgtg ttcgccaagc ctaatttagg cagtgcgttg gcagtcgctt taggtgtcct
     6541 gctggtaacg gcaatgttga ttattcaaaa gaaaggcaag gtggtgcaga cgtgaaaaag
     6601 ttaataaaac cgattttgtt ctgctttgtc ctgtattact tgctgccgat tattggaacg
     6661 attttgtatg ccagctccac taaatggtca aaatcgcttt tacctagtga ttttaccttg
     6721 caatggttcc aacagctgct gacggacagg gaatttattg ctgcggtggg tcgctcactt
     6781 ttattagcag gtgtggtctt ggtgacgatt ctgttgttga tgattcccac cattatttgg
     6841 attcatttgt atttccctcg tttgaatcgt tggctggaaa agctgctcct gctgccgtat
     6901 gctttaccag gagtgatttt ggtaacggct ttgcttcgaa cgtatgctga aactggtatc
     6961 ccaatgtttg tagtgttggt aggtgcattg tttattacgg cgttgccgat tgtctatctt
     7021 agtcttaaca accagatgcg cttaattaat ctgaaggaat tagtggatgc agcagaaacc
     7081 ttgggcgccc cgatgtctac gattattatc caggtgctgt ttccaaacat ccgtatcggt
     7141 gtgaccctag tttctctgat gattttttct tcggtttttg gggagtacat gctgacgaac
     7201 ctgttgattg gcggtcgatt tcagacggta cgcatctata tgctgcggcg gatgaacgaa
     7261 aacggccatt tggctagcgc tgtgatggtt ttgtatttgc tgtttatggt gggaattgct
     7321 ttaactacct ttatgctgac ttatcgacaa aagcaacagc tgtcccttaa gcagacgagg
     7381 gaagagaagc agtcgaaaaa gaagccctta aaggagttgt gacggaaaat gtttttagaa
     7441 atacatgatc tcaatctgtt ttttgatgaa aaacagattt tagctattga tgaaattcag
     7501 attgaaaagg gtgagctggt tactttacta ggtcccagcg ggtgcggaaa gtctacgttg
     7561 ctgcgctgta tcacgggatt ggaacaacca aagagcggtg agattgtgct ggacaatgag
     7621 aatattgccg ataagcctac gaaggatcgc aatatcggct ttgtttttca acagtatgca
     7681 ttgtttccaa ctatgactgt ttttgaaaat gtagcctttg gtttgaaggt aaagaagctg
     7741 agtcctgagg tgattcagga aaaggttttt gagatgctat cattggtgga tatgacggag
     7801 caggcagata aaaatgtcca gtttctttct ggcggtcaac gacaacgggt ggcactggct
     7861 cgctcattgg tcactgaacc gaaagtcctg ctgctggatg agccattaag tgctttggat
     7921 gcccgaatta gaaaacagct gcagcgggat ttgcgcgcta tccagcaatc gctagggatg
     7981 acgatgattt ttgtgactca tgaccaagaa gaggcgatgc gaatcagtga tcggattttt
     8041 gtgatggaag ctgggcgggt ggctcaggtt tccacctcga aggaattgta tcagaatcct
     8101 cagagccgat ttgttgcgga atttatcggc aactataatc gtttcgaatg gtatgagctg
     8161 aatcagtata cccacgagtt ttccgctaag ggcaatcgct gcatttatta tttaagaccg
     8221 gagctgattc aatttgaacc ggttcctcag ggggttaaga ttccggttct atggaaggaa
     8281 tcatttattt taggcaacat tcaacggtat gtttttcaaa cgctggaggg caaagaaatt
     8341 ttagtggatc ggttgaacga tcgggaagag aaaattagcg atgccttata cattcagctg
     8401 aaagatattc tagcaatccc tgtggaaatt gatactcagc attttgcaca acaaagctag
     8461 tgtatagtcg gcaaacattt ctggctcttt gtcaaatagg actgatagag tgatataaga
     8521 acatctaagg tagaattgat tttctgcttt agatgttttt ttatgtttaa taagtgatca
     8581 gatgattgat taagaaaatt ctggttctca tcctaacccg taagctattc gtttcaatgc
     8641 tttgatgtgg gtatgcagat tttctatttt gccatttgag taaggcaact ctaaggctaa
     8701 acgaatgccg gattcatagt ttataaacgc tttttttata tgatgcagtt ctcttggaac
     8761 cgacttgggc attgttttta caagctgaaa gaagatgtcc gcttctttgt cataaaaagc
     8821 ttgaagaatt tcttgatagt aagcataagc tattcgtagt tcatcagaag tagaaagtag
     8881 acgttctacg acttcacttt cggttaaata ggcccaacca aaattacgcc attttgtcca
     8941 tttatcataa acaagcgtgt cctgtcgttt gatcagaagt cgagataaag ccttcacttg
     9001 tcgatagtgt ttggcttgta ttggatcgtt tcggtcgaag cttttcatga ctcatagtca
     9061 aatatcctta aaactgcgaa tgaggtgctt gacgatgtga aagcgatcca caacgagttt
     9121 ggcatgagga aagcactctt ttatcagcaa agcataagag gcgttcatat ctgttacgag
     9181 tatttttacg tttaaacgtg cacgtcgttc aaattgcata aaataagaaa tgagatcttt
     9241 cttcttacgt gaaggaagaa tatccagtaa tttcccagta tcgccatcca tacaagaaaa
     9301 agaataggga ccgacttgat ttttcaatga acgaaattca tctaccaatg aacagcgagg
     9361 caaccaattt attttcacgt ttgtcatggg gagcagagaa gcgagtgttc gcgaaacggt
     9421 tgaccaagaa acgccgcaat gtttagaaat cgtcgtcatt gcttgttttt cagtcaattc
     9481 ctccaatatt ttataatgta cttgtttggc gataaaacag tttttttcaa caatgtaggt
     9541 attcgccgta aaataggtgt gacagccacg acagaggtac cgttgctttg ccaaagcaag
     9601 ataagtccgt tgattcgcac acttattgag aaggaccagc gattttttct ttccgttctt
     9661 aacgatcagc ccatgttgat tcacctgttt acactgagga cagggctgaa tcgttttaat
     9721 gagcgtggca gaaacaacga tactgttgat tgaatgtatt tttttcttct cgacatgagt
     9781 gatttgaatg tttccatctt tgattcctag taatagtttg ataagatgaa gatcaggcat
     9841 acagaacgct cctttgattg tgttgtggtg attcaattct aacggagctt ctgtatgttt
     9901 tgttttttta tgctcaaaag gactgataga atgatttact atcagtccta gaaattatag
     9961 cgccacattt ctttcacctt tgacttttca gacggcagtt tttatgctga tactgtagag
    10021 agagcaggac acagcttttg cttgttttgg gtaaggggga aagaagatga ccaaagcact
    10081 tatttttgat tttgatggga cgatgattga cagtgaatgg atgttttacg agagtattca
    10141 tcactattta ctgaagccta tttactggag cagttcggct ataaaattcc ttttgcagac
    10201 tatcaacaag gtgttgggac ggcagcagaa ctgtcctttt atgaagggat aagtcaagcg
    10261 gttgggagac cagtggatgc tgaacatttt gagcagcgga tcagcagcac tggaaaatcg
    10321 gagtagtctc aattctgaac tgcgggagct agactatttt tttgaagcac atccgatgat
    10381 taaggaaaaa attgattcct ttgtgacgat cgatgatctt caggtcggca aaccagatcc
    10441 agaaggttat ttgttgtgct tgaaacggct gagggttgaa caggctgttg tagttgagga
    10501 tagtccagtc ggtgcccaag cagcaccgca tatgacagtt gatgtacaag cgttggatgc
    10561 agattttttc gcctttagcg ggcataaaat gtgcgggccg acaggaatcg gtgtattata
    10621 tggcaaacgt caattgttag aacaaatgga gccagtcgaa ttcggcggtg aaatgataga
    10681 ttttgtcaat ctttacgata gttcatggaa agagctgcca tggaaatttg aagctggtac
    10741 tccgaacatt gcaggagcaa tcgattactt gaatgagatt ggtatggaga atattcatcg
    10801 ttatgagcaa gaactggttg cctacgtttt acctaaatta caagcgatcg gcggtatcac
    10861 catttacgga ccgcaagatc ctgaacatca tactggcgtg gttgctttta atttggatgg
    10921 catccatccc cgtgatgtgg cgactgctct ggatatggaa ggtgtcgctg tacgttcagg
    10981 acaccattgt gcacaacggt tcatcgacga tttctgtttg actaattggt cgtttaaaca
    11041 gtcgatgata atgccgtttg agcggctcca atgtcgtgga atctttgagt aagagtttcc
    11101 aatatcgctt gagccgacgg tacttcttct gattttcaga ttacgtgatt gattttcgta
    11161 cagttctatg agaatcgcct gcttcagttc ctttgttagt tgatgatgtt catcaactaa
    11221 gtccgttttc gcagaaaagg tctgcccaca atcatagcat agaaaacggg tacgttttaa
    11281 ttctaaaata gtcaactttt ctttgacttt caacatctga gtacgtgtcg tataggaacc
    11341 gttgcggata atacgaatcg atccacagtg ttcacaatgg gaaggtgagt catccaatct
    11401 ccctttaata aactgcgctt gaacgccttt atattctttt tcaatcagcc attcttcatc
    11461 aaaaaataaa tgtttatctg ttaatccgag taattttcta gtatgattat ccatagagcg
    11521 actcctttgg tagggtgatg ttttggtcga ctaaatttta ccaaaagtga gtctcttttt
    11581 gagttgaaac gaagaaaaag tgttagtaga aaatcgcctt cgattttcca acaacacaaa
    11641 atattataga agcctttttt ctaaaggatt tcaaggtgtc tgtttgcatt tattaaaaaa
    11701 aagaaaaagt attggcaaca gaaggcgtca ccaacactag atattataga gccataatat
    11761 gctgtataat atctagtgta taggcttaag tggaggtata tatgaaaata ttaactgttg
    11821 aagatgataa tatgataaga gagggaataa gtgaatatct ttcagaattt ggatatactg
    11881 ttattcaagc taaagatgga agagaagcct tgtcaaaatt taatagcgat ataaatttgg
    11941 ttatcttaga cattcagata ccttttataa atggtttaga agtgttgaaa gaaattagaa
    12001 agaaaagcaa tttaccaatt ctaatcttga ctgcatttag tgatgaagaa tataaaattg
    12061 atgcatttac taatttagta gacggatatg tagaaaagcc attttcattg ccggtcttaa
    12121 aagctagaat agattcttta attaagaaga attatggaca tttagagaag tttgaatata
    12181 aggatctatc
//
LOCUS       DACDLM010000081        12125 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.083, whole genome shotgun sequence.
ACCESSION   DACDLM010000081 DACDLM010000000
VERSION     DACDLM010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12125
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.083"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..1740)
                     /gene="uidA"
                     /locus_tag="IV356_002378"
     CDS             complement(<1..1740)
                     /gene="uidA"
                     /locus_tag="IV356_002378"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003479936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HAP9016028.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRK"
     gene            complement(1763..3529)
                     /locus_tag="IV356_002379"
     CDS             complement(1763..3529)
                     /locus_tag="IV356_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HAP9016029.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(3542..4336)
                     /locus_tag="IV356_002380"
     CDS             complement(3542..4336)
                     /locus_tag="IV356_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAP9016030.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            complement(4346..5722)
                     /locus_tag="IV356_002381"
     CDS             complement(4346..5722)
                     /locus_tag="IV356_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP9016031.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKASNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFLYPLSKDKVLENC
                     ELLKQKHK"
     gene            complement(5842..6489)
                     /gene="eda"
                     /locus_tag="IV356_002382"
     CDS             complement(5842..6489)
                     /gene="eda"
                     /locus_tag="IV356_002382"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HAP9016032.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(6573..8000)
                     /gene="uxaC"
                     /locus_tag="IV356_002383"
     CDS             complement(6573..8000)
                     /gene="uxaC"
                     /locus_tag="IV356_002383"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HAP9016033.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(8074..9153)
                     /gene="uxuA"
                     /locus_tag="IV356_002384"
     CDS             complement(8074..9153)
                     /gene="uxuA"
                     /locus_tag="IV356_002384"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAP9016034.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(9156..10787)
                     /locus_tag="IV356_002385"
     CDS             complement(9156..10787)
                     /locus_tag="IV356_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAP9016035.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            11091..11762
                     /locus_tag="IV356_002386"
     CDS             11091..11762
                     /locus_tag="IV356_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP9016036.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
BASE COUNT         3890 a         2415 c         1566 g         4254 t
ORIGIN      
        1 ttttctatct ctagtaaaga ttcctttctt atttccttgc actcttaaaa tcccttgact
       61 tgttgcaaaa tctgcaaaat tccacacttg ttcaccaaca aaattttcac atgtatctat
      121 tacttcgtga tttgcttcgt aataagccac ttgatactct tctgtaaaca ttgttggtac
      181 tgtatcatga aatccagcta ctgtatctgc tccatattct gtaaacatta ttggcgtatc
      241 aggacatctt tccatccatc catctagctc ttttttcaac agatattttg catgtgccag
      301 atcccctccc gaaacatacc aaccataata acgatttaaa cataaaacat cgacaatatc
      361 tcctacctta caaacatctg gcgttgattt tagataagta acgattgtta caggtctttt
      421 ctgcggatca agttctttag ttaattcaac taaaggttca aaatattctt tagcaccttc
      481 ggaatccgaa tctggttcat ttgcaataga ccacattaca acacttgggt ggttcttgtc
      541 gcgttctatc aattccttga tcaccgtttt atgagaattt tctgttcgta tctctttcca
      601 cgtattatgt ttttccacat tatcatctaa taaagtggcc atgaaattta aatgtaaccc
      661 tactgcaggt acttcatcaa taactacaat accttctcga tctgctaatc gcataatttc
      721 ttctgagtaa ggataatgtg atgttctaaa agaattagca cctatccatt tcattaaatt
      781 aaaatcttta atatttacag cctcattcaa accacgtcca ttaacatacg aatcctcatg
      841 cttaccaaat cctttaaaat aaaaaggttt attattaatc aaaaatttgc cattggtaac
      901 ctgaacactg cgaataccaa attcttctgt ataggtatcg atcactttat tatcatcaat
      961 taaactaatt ttcatactat ataaataagc gtctagaggt tcccaaaaaa ttggattctt
     1021 aagctgaatc attcctttct ttccttcagc ttcagctaca agttgagcct cttcgtcata
     1081 tatcgctatt aagatttttc cggtccattc tgtatcgata ttgaattcta cacttgcatc
     1141 caaatcagtt attcttgtat taatagtaat atcacttata tagtctttcg gagttgtata
     1201 taacttaaca ggtctatgaa tacctgcata attgaagaaa tcaaaattaa ctaagttttc
     1261 cttttttata tccccatttt cctgtactgt ttccttcata atccccacag gtaaagtact
     1321 atcgtcaata atattgttta cagcaactgt aattcgatta ttcccgtctt ttacaaaccg
     1381 attaatttca gactcaaatg gtgtaaaccc acctttgtgt tgagtaataa actttccatt
     1441 caaaaaaact tttgcttcat gtgttgcaga tccaaaacga agaactaatc tttcttctaa
     1501 taatctttta ggaagagtca cttctttttc ataccacacc catccaacat gatttctaat
     1561 gttctctgtt tcaaataaat cattataaga agagggaact gaaatcggat aactctcttt
     1621 ttcatttatt ggttctaaag caagttcttc ctgtaagtca tcatttgtat ctaatttaaa
     1681 tctccagaga ccgcttaagt caattacttg cctcgtctct gtcataatgg gatacaacat
     1741 ataaaccact cctatctaaa tattaaataa atgtatcctt taaaccacaa taagcatcta
     1801 ttggacttac tcccttaaat tcagaaagac ccattagttt gtccaccaat atttctaaag
     1861 tttcttgttt tccatcataa gtattaatat aagtctttac ttgaggtaca tcagccaaat
     1921 gaaacggaca ctgtacagat acaaaaattg ttggaatttc atgaatgtaa aacggtatat
     1981 ccggagttcc tttacttgct ggccagacaa ttcgttgaac tgtgcctgga ttaacattag
     2041 ctatattaat gatcaagtca tattttttag ttaaattttt aattggtctc ttagcagcat
     2101 atattccagc tatattttta attttttctt cttgcgataa tcctttcaat tcttcttcag
     2161 gtgaaatgta tttttcaact tcaaatcctt ttgctgacaa aatctgtttc aataaatcaa
     2221 tggcttgagg tctatttcca gcaactactt caccaaaccc accttttacc ccatgtacat
     2281 ctactagtaa aatcctttta tatttttctg gtacaatagg ccaaatatct tgtttatctt
     2341 taactaatgt aattgcttgg tcagccacct ctttaaaaat tgatttattt tcaattaaac
     2401 caattttttc cagagcttct tgcttaggta ataaaatttg ttcttttgct tttttgtgta
     2461 atcccaattt agcttttaac cctaaaattc tttttaaggc atctaataac cgatcatcag
     2521 tgataattcc tttacgatag ccttccatca tataattaaa gtcttcatct ggatcattaa
     2581 aaaatagaaa tagatcacat ccagctgcaa tagaagtggg caataattct gatcgtttca
     2641 ttgccccagt cattcctaac atatgactag catcagtaac tactaatcca ttaaatccga
     2701 gttttcctct aagtaagtca gtgattaatt cttttgataa agttgcagga agtaaatctt
     2761 catctttcag atcaggatta aaatgttttg aataagctgg catatggata tgacctgcca
     2821 taattgaagg taatccagct tctattaagc ctgagtatac ttttccaaaa gaattatccc
     2881 attcttccgt acctaaacta ttaatactaa aagatagatg ctgatctcgt tcgtcaatac
     2941 cgtcaccagg gaaatgttta gctgcaggca aaattccact ctcctgaata cctttcatat
     3001 aagctaaact aagttctaaa actttatcag ggttttgtcc aaaagatcga ctagaaatga
     3061 taggatttct ccaatttcta ttaatatcta caataggagc aaaactccag ttacatccaa
     3121 tagccgatgc ttcaatccca gaaactctcc ctaattcata agcatatttc gcatcatttg
     3181 ttgcaccaat ttttacttct acaccaactt cagtaccatc tgtacaagct ccgttaccac
     3241 ctgcttccgt attagcagca attaatagag gaattttact ttctgtttgt aagatatagt
     3301 tttgatcata tacctcatca gcagttcctg gattatatcg tacagctcca atatggtact
     3361 gattgaccat attactcaag taatttttat cacgactaga tcccatatta acaaacaatt
     3421 gacctatttt ttcttccaaa gtcatagaat caatcgtctc ttcaatccaa gaaatagcat
     3481 cttcatctaa attatatggt ttttttcgta aatctacttt tatagtcatt ttctttctcc
     3541 tctacttatt agtaagattt ttccaaaaag tatctatata tttttgttca atatctacat
     3601 aatctcccga taaacattta aataaaacat cagttcttaa gttttcccat gattcttttt
     3661 ctttattgac caaaatagga taaaagaaaa ctttattttt atttgcagct tctagatcac
     3721 caggagaatc accaatcatt aatatcttat ccaaatcaca accattttca attacacttc
     3781 gaataatatc ttcttttttt cctttatctt gacaacacag ttcatcaact aatgataata
     3841 attcatgtct ttcccattct tcttgaacag cttccttatt agctgagctt acaataatta
     3901 tcttcccata ttttttcaga gcttttatag tatctctagc acttaaaaag ggtttatcta
     3961 atccttttgc ttgactaatc tgttgattga cttcttccga ccattttaaa gcttttaata
     4021 aatcctctga ctgagaatat tctatttccc tcttcaaaga tggattagac aattcttttg
     4081 ttagagatac ccagtgcttt aatcgattaa tcgatgttac atcatttttt tctaatgttt
     4141 taactaaacc taaaaatctg tttattccac gagtctctga atataaatta atattattcc
     4201 aatcctgtag gaatttttct ctatgatgaa catcaaaaat ctctgcagca attggtccga
     4261 aaaagagatt gtgtttataa gtcatcgtat ccataacaca gccatctgaa tcaatacaaa
     4321 atatccaatt attcatattt ctctcctatt tatgtttttg ttttaaaagc tcgcaatttt
     4381 ctaagacttt atctttagat aatggataaa ggaaaaataa aattaatcct acaatcagaa
     4441 aacaaattga tggaattaat gttgaagcgt tatataactt ttctaaaaca tctcccgttt
     4501 gtacatttgc taaagagtca tagcctataa tagaaagagt ccaacctccg acgcctccag
     4561 ctagagcttg acctattttt ctagcaaaag aatataccgc atatacggtc ccatcttctc
     4621 tttgatcaga ctttacttct tgatcatcaa taacatcagt aatatttgcc caaataacag
     4681 tattaaacac acccaaaccc atatagccaa ccgaactaag aattaagaat acatacatat
     4741 tactagcttt tatcaaaaat aagatcaaat atactattgc tgaaaagaac attcctactg
     4801 atgccagttc tttttttcca tattttttac ttaaaaacaa agttaaaggc gaaacaacta
     4861 ttaaaaccaa aataggattg ataaaattca ttaaaactat tccctgtgca tcattatagt
     4921 aatcaggaaa tacataatta ttcatactca taattaataa ttgagcaagg agtaagaaaa
     4981 tagccgcacc aattatagaa agtaatgccc tatttttaac taaccctttt aaagatttta
     5041 acaatgaaac tttgtattga gattggtcaa ttcttactcg ttcagtagtt agtttataac
     5101 atattaaata acaaataagt gcacatatcg aaaatattcc cgcaacaatt gtaaaagttg
     5161 atccaccacg aactatttga gcgcctgaat catctcttgt ataaataaat aatggtgtta
     5221 atacaccaat gaccaaactt gctaaagtag ctccaacatt tcggaatgtc gatagcattg
     5281 ttctttcttc tgtaatagaa gtaatagctg atgccattga tccataagga atatttatag
     5341 atgtgtaaaa aatactcccc cataatatat acgtaacata catgtatact accttaacgc
     5401 tcatagaagc tgaaatcata gaagtttgat acattaaaaa acttgctaaa gcgactggac
     5461 cactcattct taaaatccac ggtttaaact taccctgctt agttgctttc gatctatcaa
     5521 caatacgccc catagttaca tcagtaactg catcgataaa tcttgctact aaaaataatg
     5581 ttccaacggc agctccgctt atccccaata cttttgtata aaagatcatt aaaaaagaac
     5641 tagcaaaaat gaaagtaaaa tcgtttccaa aatctccaaa catatatcct attttgtctc
     5701 ttataccaaa ttttctttcc atacaattct ctcccttctg ttgttaagcg ttttcattct
     5761 gatgaaagta cgtactatac tctgaagcgt aaagagtcag tatttatttt ttacatttca
     5821 gagtattatt tgttttttct cctaataatt ctttatctca taaaacttat ctatatattt
     5881 actagctact cgacttactt cttcaaaatc acctttttca acagaagcca ataaattccc
     5941 acctacacca actgcaacaa ctcctacttc aaaccaatct tctaagttct ctatacttac
     6001 tccgccagta ggcattatat ttacgtgtgg taatggagct tgataggctt ttacaatgga
     6061 tggaccaaaa gcagaacctg ggaatagttt aatgatatct acgccagcag taagtgcctc
     6121 ctttatctca gtaattgtca tacaacctgg taaataagga atttgatata aattacaaat
     6181 ctcagctgtt tgtcgatcaa aagatggact aacgatatat tctgccccag ccataattgc
     6241 gatacgagca gtaaacgcat ctaaaaccgt accggctccg attattacat ctttttgatc
     6301 agcatatttt ttagcaattt ctttgattat ttcttcagca ttaggaactg taaaagttag
     6361 ttcaatccct ttaattccac ccgcaataat tgaatttatt gctttaatgg cctcatcctt
     6421 atttttccca cgtacaaccg caatgactcc agccgcttct aacttactta aaatttctac
     6481 ttttttcata tctatctcct tcctttatgg atacatactt tgtctagctg tactaactta
     6541 caaagaataa atttaagctt ttatttcaag tattattttc tacttccgat ttcaaaaaaa
     6601 ttaaaataat tatacgcatt acgataacaa atattctcca ctatctgact aagatacatt
     6661 tcatcatctg gaattcggcc tgctttaacc cactcgctta gtaattgaca taatactcga
     6721 cgaaaatact catggcgagg atagcttaga aaacttcgag aatcagtcaa catacctgta
     6781 aaattcgaca acaaactttg ttgtgccatc gtagtcaact gttgacgcat tccttcagct
     6841 gtatcattga accaccaagc acatcccaat tggatttttt gaatcatacc cccttggaag
     6901 ctttgcattg ctgttgctag tggaagccaa tcagttggat ttaatgaata taaaattgtt
     6961 tttggtaagc acccactctt ttcagcggta tcgaacaatg ctacaacatt ttgtgtcaaa
     7021 ctagcttgat cccccatcga atcaccaccg acatctactc caatttgttc ctttaatata
     7081 cttgaattat ttcttaaagc atttaaatgc atttgcatcg tccaaccata tcttgtatac
     7141 tcagacatca aatgtaattg aatacctgta acaaattgtg caatttctga taaatggaaa
     7201 tccgtttttc ctgctaaagc ttttattaac agattgtcga gtattttttc atctgctatt
     7261 tcataaaaat aagtattcaa accgtgatct gctaatcgac agccaatttg atgaaaatga
     7321 tccactcgtt ggctcaatgc ttgcttcaac ccattaaagt ctttgattgg tatagccgct
     7381 gtttgactaa gttttaaaat atagttcgaa aagcctgatg atttgatact ccagacctta
     7441 tctggacgga aagtaggtaa taccttgaaa gaattatcct gtttagaaag ctcagtatga
     7501 taccacaagt catctgtagg atcatccgtt gtacagatgg ctttcacatc catcatctcc
     7561 aacaattctt tcgggcgata ggaatccgtt tgaatttttt cgttagcacg tcgccaaatt
     7621 tctggtgcat tcttctcaga aattgtcaaa tcaatatcaa agtaacgttg taattccaaa
     7681 tgagaccatt caaaaatagg attacctggc gccttctcca ctgtttttac aaaagctaaa
     7741 aatttttcat aatcatcacc tggaccactg atcaactctt cttctatacc attagctcgc
     7801 atcaatcgcc atttataatg atctccagct cctttatcat ttaaccatac ctgagtcaaa
     7861 ttcttgtatt gcttattttc tagcaaatat gctgggtcta aatgacaatg atagtcgata
     7921 attggttggt gttttgcaaa tttatgaaaa agtcttttag ctatttcatt ctctaataaa
     7981 aagttcttat ctaaaaacat atttaaacac tcctttcctt ccgttagttt ttagaagaga
     8041 aaatttttcc tctaaataaa ctcccttata taattattta ctcgccccct tttcaagcgc
     8101 ttcccaaata ccatttaaat aaactgcacc tagagctcgg tcatataatc cataaccagg
     8161 tctaccggtt tctccccaaa tcatccgacc atgatctgga cgaatatagc cattaaatcc
     8221 attatcgtac attgttttta atatcttata catatctaga gaaccatatt ctgatttatg
     8281 cggcgcttcg taaaaatcga gtccattgtc acttaaatat ttgatattac gaacatgtgc
     8341 aaaaggaatc cgatcccgtt gacaaaattc agatagaatt tcatagacat cattatctgg
     8401 tcgttctgca atacttccag tacataatgt aataccatta gaaggagaat ccactacatt
     8461 acacaaccaa tctaaatcgt cacgattttt aacaatacga ggtaatccga aaatggaata
     8521 tggtggatca tctgggtgaa ctgccatttt aatcccaact tcttcacatg tcgggataat
     8581 tgctttgaga aaatatgcaa agttctctcg taatttctct tcatcaactt ctttataggc
     8641 ttctaataat tgcttaattt gtgataaccg atgaggttcc caacccggca attcaaaatt
     8701 attagtagaa ttttctactt ctctaataat ttcctccgga tcagtaggga tattttttga
     8761 aatataggct aacgtagaag acccatcatc taaacgataa tccaaatccg attttaccca
     8821 atcaaatact ggcataaaat tataacagat aacctcaatc ccaaattctg ccaaattgcg
     8881 aatcgtctgt ttataattct caatgtattg atctcgtgtt ggtaaaccaa ttttgatatc
     8941 atcatgaaca ttaacactct caataacttt caaggtaagt ccattggctt cgacttcatc
     9001 ttttaaagat ttaattcgtt ctctcggcca aacctctccg gctggtatat ccattaatgt
     9061 tccaacaatt cctttcattg ctgggatctg acgaatttct tgtagtgaga ttttttcttc
     9121 atttgcccca taccatctaa aagtcatttc catagttact ttcctccaac ttctgttata
     9181 tatttattga ttgttttacg aactgcttga ggacctacta gcatttcgca aaagattttt
     9241 tcagttttct ttcctacccc aacttgatat aaatctaaac caaagatttc tttattttct
     9301 aaaatttcct gtaccgcaca atgaatcttt gaaggatctt gttcacctaa tttcaatact
     9361 gataatttat cctgcaactc taccaataac ggatcaggac ttggcacaaa attttcccct
     9421 tgatcatcga ctgccagtaa ataacgtaac caagcagcaa tagcgatagg aataaatgtt
     9481 agattttctg catttccgtc tttttcgaca tactttttaa ttgtttcacc atagcgaatc
     9541 gctacttttt gagaagtatc tgttgcaatt cgttgtggtg tatctggaat atagggatta
     9601 ggcaaacgtt tattaattac ttcatcaata aattgttttg gatcaataat gcctggattt
     9661 tcaactactg gtaaaccttc taaataacct attcctttga ttaaaccaac caaatcatca
     9721 tcctgcatct ctgctgaaat tgattgatat cctagcagac aacctgttac tgccaaagca
     9781 gtatgaagtg gattcaagct tgtcgtaacc ttcatgatgt ctgctttatc aaccgtctct
     9841 ctatctgtca taatcacacc agccttttcc aatttaggcc ggccatttgg aaaactatct
     9901 tcaataacta aataatgaac tacctcagta ttagtgaaag cagcaatatt ggtatgtttt
     9961 tttgtgtgaa tgatatctaa atcctcgagc cccatcatca atagatcttc ctttacattc
    10021 tctgaaggat ttggcgtaat tcgatcaatc atactccaag gaaaagtcac tttttcttta
    10081 tcctttaaat aagcaataaa tttttcagaa acatatcctt ctttttgcca agcttctgca
    10141 atcgtaaaaa tactatcttg aaaacgttga ccattctgtg agaaattatc agtagaaacc
    10201 atcgcaatcg gcaactctcc agcattaaat ctgctatata acaaggatgt tacaatactc
    10261 atcgtatgtt gaggattgct aggtccagat ttgatatcag ctttgactac cgaaaagaat
    10321 tgccctttag aatcttttaa actgtaacct ttttcagtaa tagtaaacgt tgtaaactgt
    10381 aatttaggat cttcaaaata tttaaccact ctttgatagt ccgctatatt cttcggattg
    10441 caatataaac tatcagccgt tactgccaaa agtctttttt tgagttcacc atctccactc
    10501 ataacaattt ccaaaatgtc attgttatag tcatgataag ctttttccac tacttcttca
    10561 tcaaatgttt cacacacaac tactcctgtt tctaattcat tttgatctgc taagcattga
    10621 gcaatttctg catgaaatcc tcgataaaga tttcctccac caaaatgaag ccatactgga
    10681 tgttgctggc cttcttgctt aacttctttg acatcaaaac acggcagtag aatctgcatt
    10741 tcattgaatt cttcgataga attttgccaa tttttaatcg aaaccataat taacctcctc
    10801 aaactgatat gttagttttg atacatttta tattttaaaa cccattgtaa ccgttgtcaa
    10861 tataaaaagg gaataaactt gcttttttct accatatcag aatgattgta ttttttattc
    10921 agaaaaataa aatactcctt ctttttggac tgattttatc gaaacttatt ttttcttttt
    10981 ttcatgtatt cttttatttt tataactagt gtattacttc aaaatttgat attatatggc
    11041 atgaacagaa ttaaaatatc agttaaaata aaagttaagg agcattgtgt atgacaatta
    11101 aaactagtct ccaaaatcaa gcttaccaat ctattcgccg acaaattatc tatgctgact
    11161 tagaacctgg aaaaaaagta tcagaaaaaa aattagaaga aacactttct attggtcgta
    11221 caccaatacg tgaagcactg attcaactcc gacaacaagg tcttgttgat acaattcctc
    11281 aaagcggaaa ttatatctca ttaattgatt tagattcggc caaaaatgct cgatttgtca
    11341 gagaacattt ggaacgacaa attatgttag agtgttgtgc caaaatgaat aaccaaaaaa
    11401 aacggatttt agaaactata atttcagaac aagaaaaagc tgttagtcaa aaaaatgctc
    11461 gtagtttttt tcataatgat aatttattcc ataaagcttg ttttgaaatt gcagagcgag
    11521 aagaagtatg gcaatggtta gaaaataaca atacacactt agaacgattt cgatggctac
    11581 gagtaaaaac ggaaggatta aagtgggaaa aaattatgga acaacattat caactatttg
    11641 aggcattaac aaaacaagat ccagaagaag ctaactttct aacatcgttg catcttcatt
    11701 taatgcttaa tgagcaaaat attgttttag ctactcatcc aaaatatttc aaaaatatat
    11761 aacttttaac tctttttaaa ttaaatggtt gttctgatca gaaaaatatc gcttgttttc
    11821 ttattatgta atatatttca taaactattc tgcataacaa ctattgtttg tactttttac
    11881 attggataac taattatgac tgctgataac ttttgatatt aaactagtat ctccaataca
    11941 aataaaaaat agatatcttg ttcatcaaaa ttagttcgtg gatacttacc ttcatttaca
    12001 tcattcagcg gtttcccatt ttcttttatt ctattatttc attttctaat agacttggct
    12061 tcatttcgca atactttttt tcaataggca tcaaattggt gttgtttaga tatttagttg
    12121 tagtt
//
LOCUS       DACDLM010000082        11630 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.084, whole genome shotgun sequence.
ACCESSION   DACDLM010000082 DACDLM010000000
VERSION     DACDLM010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11630
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.084"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            253..522
                     /gene="rpsN"
                     /locus_tag="IV356_002387"
     CDS             253..522
                     /gene="rpsN"
                     /locus_tag="IV356_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAP9016037.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            537..716
                     /gene="rpmF"
                     /locus_tag="IV356_002388"
     CDS             537..716
                     /gene="rpmF"
                     /locus_tag="IV356_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAP9016038.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            748..1125
                     /locus_tag="IV356_002389"
     CDS             748..1125
                     /locus_tag="IV356_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016039.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            1146..1295
                     /gene="rpmG"
                     /locus_tag="IV356_002390"
     CDS             1146..1295
                     /gene="rpmG"
                     /locus_tag="IV356_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003550836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAP9016040.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            1319..2302
                     /locus_tag="IV356_002391"
     CDS             1319..2302
                     /locus_tag="IV356_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAP9016041.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVIADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLEKFNHPLVFESDSSENH
                     YNGKHYHQHHQEHEFKSILLTSDQDIKKDFLFQLIDRLILTNQGSLYRFKGLIALQDQ
                     DFIVAIQGVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            2332..2454
                     /locus_tag="IV356_002392"
     CDS             2332..2454
                     /locus_tag="IV356_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAP9016042.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKQNKMKKLA"
     gene            2472..3995
                     /locus_tag="IV356_002393"
     CDS             2472..3995
                     /locus_tag="IV356_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAP9016043.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLIQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKLNKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNEMHNWPTFYPASLSEHEIAQEMMAH"
     gene            4019..4258
                     /locus_tag="IV356_002394"
     CDS             4019..4258
                     /locus_tag="IV356_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016044.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYQFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(4451..5086)
                     /locus_tag="IV356_002395"
     CDS             complement(4451..5086)
                     /locus_tag="IV356_002395"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP9016045.1"
                     /translation="MVRHLFVDFQWSPEKISNRLKHEHMDFSISFITIYRAICNDLFD
                     TEPLSHGNKGLIRSLHHRGKTRHTKNHVESRGKICLTHSIHGHPKSADDRSDFGHWKA
                     DIVAGKTSGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEVLNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(5107..5325)
                     /locus_tag="IV356_002396"
     CDS             complement(5107..5325)
                     /locus_tag="IV356_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP9016046.1"
                     /translation="MSQYCHLTILKRERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTNHLPKRKKIMLIEEKNADVITF"
     gene            5634..6461
                     /locus_tag="IV356_002397"
     CDS             5634..6461
                     /locus_tag="IV356_002397"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HAP9016047.1"
                     /translation="MPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGISKPIPII
                     QAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVVEEEQDI
                     RGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVDLSKILN
                     TNLFNIDETSYSMGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFAHLTDKN
                     FPGNITRAKGFLWFAQHSDFSTIFETSGSHKSIESLNYWVASLPKIECQMIIQKNPN"
     gene            6650..7057
                     /locus_tag="IV356_002398"
     CDS             6650..7057
                     /locus_tag="IV356_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HAP9016048.1"
                     /translation="MKFLRKAGVKIGDVIIIGILIIPSFIPLFVFSIEKENETTEDAI
                     KYAIVQIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVR
                     TGWISKPGQTSICLPHKLVISIEKKESKDYYIY"
     gene            complement(7298..8638)
                     /locus_tag="IV356_002399"
     CDS             complement(7298..8638)
                     /locus_tag="IV356_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP9016049.1"
                     /translation="MSYSEFTKELLDILDLNLTFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTIVRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPISMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKGDRRS
                     KHLKKYWRLLQKNAWELNGQHRYWRPSFRDHLTEAEIVDRLLYYDDSLKRGYEVYQVF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYRERIFLYRGKYFKKTKNTTQLTKARTTTRLDKIAV"
     gene            complement(8914..9069)
                     /locus_tag="IV356_002400"
     CDS             complement(8914..9069)
                     /locus_tag="IV356_002400"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HAP9016050.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLTDHHITHSMSQTGTPVDNAVIE
                     AFHRSIK"
     gene            complement(9253..9456)
                     /locus_tag="IV356_002401"
     CDS             complement(9253..9456)
                     /locus_tag="IV356_002401"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAP9016051.1"
                     /translation="MFYEHKDRYGSPGITQKLYDEGIEINKRVVAVLMREMNLCTRGF
                     HRRKSSHGREKTIKEMVKKMLNR"
     gene            complement(9366..9698)
                     /locus_tag="IV356_002402"
     CDS             complement(9366..9698)
                     /locus_tag="IV356_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP9016052.1"
                     /translation="MKKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            complement(10212..10403)
                     /locus_tag="IV356_002403"
     CDS             complement(10212..10403)
                     /locus_tag="IV356_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP9016053.1"
                     /translation="MNTLKEDFILAKNGNEEAVVAILKRFSALVHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            complement(10501..10887)
                     /locus_tag="IV356_002404"
     CDS             complement(10501..10887)
                     /locus_tag="IV356_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAP9016054.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFNKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
BASE COUNT         3868 a         1818 c         2230 g         3714 t
ORIGIN      
        1 gtatttgtgt ttgattggac taataaaagt gaattcttat ttttcagagc ttaaactgca
       61 tattctttta aatgatttga ttatctctat gtaccgataa attcgttttc aaatagttat
      121 ctattcatat gagttttatt tcatgttatt tattgttgac aagagcaact cttgttggta
      181 aagtatcagt gtcaaaacgt aacgattacg atttgagatg tctaaatcaa aataaaagga
      241 gtataaaggt atatggcaaa aaagtcgaaa attgctaaag caaagaaaca aatggcgatg
      301 attgaaaagt acgcagataa acgtcaggaa ttaaaagccg caggagatcg caccgctctc
      361 gctaaattgc caagagattc aaatccgaat cgtctgaggc ttcgtgatca gacggatggt
      421 cgtccaagag ggtatatgcg aaagttcggt atgtcccgta ttaagtttag agaacttgcc
      481 catcaagggt tgattcctgg agtaaaaaaa gcaagttggt aaaaggagga aatatcatgg
      541 cagtaccagc aagaaaaaca tctaaggcga agaaacggtt aagaagaact catcaaactg
      601 tagtaaaacc agaaatttca tttgacgaag cgaatggtga ttatagacgt agccatcatg
      661 tatctttaaa agggtactat aatggaaaga aagtaattaa aggagcttca aaatagttta
      721 atatataact tttaggaggg aatcaaaatg gaaattattt acccaccttt agttgaagaa
      781 ggattaaagt attatcttga aacgacccag caatcgctag ataaatgcac tttttatcgt
      841 tcgatggtag agagaggaat tattactgaa acgggtttac cgacccaaca ggcaattgaa
      901 aatggattag tcaaagatta ctatgaggac caaggcttat catttgatga ttttttaaga
      961 atctatccaa tttttgaaga gtatgacgag gagttatttc aatgtattga tggttattgg
     1021 gagatacctg ttgatatgaa agaaaattta gtttcacaat tggaatctgg cgagttaact
     1081 tttgaagatg cacaacaaat tcaagcatat cttgaagatc gataagtatt gaaggaggaa
     1141 gatttatgcg tcaaaatatt attttggaat gtgtcgaaac tggagaacgt ctgtatctca
     1201 ccagcaaaaa taaacggaat aaccctgaac ggttagaatt aaaaaagtat tcgccaaaat
     1261 tgcgcagacg ggcaattttc aaagaagtga aatagctaag tggtaaaaag gtgacaaaat
     1321 gggcatacca gttacaatcg tttctgggtt tttaggggct ggaaaaacaa cgctaatcaa
     1381 tcaagccttg caagtctcac cctaccccag ggaagaaatt attataattg aaaatgagtt
     1441 tggtgaagtt gggattgatc acaaattatt agttcatagc gaggaacggg tgttacaact
     1501 aaataatgga tgtatgtgtt gcagtcttcg cagtgattta ttagcaatat tgatttcttt
     1561 actggaaaca atagaagaac atcaacaacc aatttcacaa atcatcattg aaactacagg
     1621 tatagcagat ccccaaccaa tcattcaaac acttttaaca gcgcctcaac taagaggaag
     1681 agtatatatc gatagtttat tgactgttat tgatagtgac agttttgaac ttattgaaag
     1741 agaaccacaa gcccttaagc aacttgtcat agcagatcgc atttttgtgt ctagaaaaca
     1801 aaacttgaat ttatctgcac taaaaaaatt acagagagaa atcaaaagta ttaacccttt
     1861 atccgatatt cgaatgttca cacatagtga aacgattcaa aaaaaggatt tttataattt
     1921 ggaaaaattc aatcatccct tagtttttga aagtgattca tcagaaaatc actataatgg
     1981 caaacactat catcaacatc atcaagaaca tgagtttaaa tcaattctct taacttcaga
     2041 tcaagacata aaaaaagatt ttttattcca attaattgac cggctgattt taaccaacca
     2101 agggagcctg tatcgtttta aaggattgat tgctttgcaa gatcaagatt ttatagttgc
     2161 catacaaggg gtaaacgaac aggttaattt tcaatacacc actcgacaaa aagaccaaac
     2221 cactattatt ctaattggaa aaatgttgga tgaagaaagg atcaaacaga gttttgataa
     2281 attactggcg gaaagcaaat aatgataagt attgattagg ggtaatttct aatggagaaa
     2341 acggatatat ctagtgcata tcgacgactt aaaagcccga atatcaaaac tagaaaaagg
     2401 gcattaaaaa ttatcaaaga acataaacaa aataaaatga agaaattagc ataattaagg
     2461 aaggaaaaag aatgaagaaa atcagtgtag gacttattgg gatagcagct ctaggattat
     2521 tgggagcttg ctccagcact aatgatgcaa aagtatcgaa tgataaagat ggaaaattag
     2581 aaattgtaac aacattctat ccaatgtatg atttcaccaa aaacatcgtc ggcgatgaag
     2641 cgaacgtgga tttaatggtt ccagcgggat cagaacctca tgactatgag ccctcagcta
     2701 aggatatggc aaaagctcat gatgctgatg tttttgtata tcataacgaa aacatggaat
     2761 catgggtacc aaaagctaaa gaaagttgga agaaagctgg gcctaatgta gtagaaggaa
     2821 caaaagacat gattttattg ccaggtagtg aagaagaaga tcatgatcac ggagaagaag
     2881 atcaccatca tgaactagat cctcatacgt gggtttcacc caaaatggca attaaggaag
     2941 tttcaaatat caaggatcag ttagttaaat tgtatccgaa aaaagcaaaa gtatttgaga
     3001 caaatgctga aaagtatttg actaaactga aacggttgga tgctgactat accactagtc
     3061 ttaaagaagc gaaacaaaaa agttttgtga cacaacatgc agcctttgga tatttagctt
     3121 tggattatgg attgatacaa gttcctattg ctggactaag tcctgaagaa gagccatctt
     3181 ctggtcgatt agctgaatta aaagagtatg ttaaaaaaaa taagatcaat tatatttact
     3241 ttgaaaagaa tgctaatgat aaaatcgcaa aaactttggc caatgaagct gggataaaat
     3301 tggaagtatt gaatcctctt gaaagtctta caaaagaaca aatggataat ggtgaagatt
     3361 atgtttcagt aatggaagac aatctaaaag cgttagagaa aacaactatg gttgctggtg
     3421 aagaggtagt tccagaaaaa gaagcgaagg atgaaaagac agttgctaat gggtacttta
     3481 aagatgccga tgtgaaggat cgcgaattga gtgattatac aggcgaatgg caatctgttt
     3541 atccgttgtt aaaagatgga attttggatg aagttttcga ttacaaagca aaactcaata
     3601 aagacatgac agctgccgag tacaaagatt attatactac tggctataag acagatattg
     3661 atactatcaa cattaaagac aacaccattg attttgtagt caacggtgaa catcatcaat
     3721 acacatacaa atatgttgga tacaaaattt tgaattatga aaaaggaaac cgtggtgttc
     3781 gttttaattt tgaaactgat gatgcaggtg ctggtcgttt taaatatatt caatttagcg
     3841 atcatggaat tgcaccaagt aaggcagagc atttccatat tttctttggt ggagaaagtc
     3901 aagaaaaact ttataatgaa atgcataatt ggcctacttt ctatccagct tcattatctg
     3961 agcatgagat tgctcaagaa atgatggccc attaaaatcc aatctttgga ggaaatacat
     4021 ggtaagaaaa gtattattgt ctatggattc caagaatatt gatgcttatc ggcgttatca
     4081 atttgcaaag caaatgagat taaatgggag tacattagct gatattgctg caactttaca
     4141 tgttagtatt gacacagttc atagagtatt aaaacgggat cctgattgtt gttttatcaa
     4201 ggtcaatact ggaagaagta gacgtttagc aaaacggcat aatagcttgg ccaattaatt
     4261 gataatacca gagtagatca tttttccctt atttggattt gatctgcttt ttattatttc
     4321 ttgaattgtc aaatcaagcg caacacttta tcaaagaaga cttcataagg tgttctccaa
     4381 tctaaacact ttctaggtct gttattcagt ttttcaatca tctgatttat cgttgagtta
     4441 tctaccgtag ctatctcttt cgattttggc aagtattctc gaatgagtct attcgtattt
     4501 taatttgttc attgttgcca agggcatgag gatctggaaa ataaaagggc atattattca
     4561 atacttctgt aactgcgaaa tgattggaga attcttttcc tctatctgga gtgatcgttt
     4621 tgaccgcctc atttggaata ctgcttaaaa gttcaatcat tttctcgctc acataagcgg
     4681 ctttctttct ggggaccttc tttcctgcta aaaggaagca tgattttctg tctgtcaaag
     4741 tcactaaaca agtaccacta gttttgccag ctacaatatc ggctttccaa tgaccaaaat
     4801 cacttctatc atctgcggat tttggatggc catggatcga atgagtaagg caaatcttcc
     4861 cacgagactc gacatgattt tttgtatgtc ttgtttttcc tcgatggtgc aatgaacgga
     4921 tcaggccttt attgccgtgt gagaggggtt ctgtatcgaa aagatcattg caaattgcac
     4981 ggtagatcgt gataaaacta attgaaaagt ccatatgttc atgcttcaaa cgattcgaga
     5041 ttttctctgg cgaccactga aaatcgacaa ataaatgacg aacaattgac caaactcacg
     5101 gatcatttag aatgtgataa cgtccgcatt tttttcttcg ataagcataa tttttttccg
     5161 ctttggaagg tgattagttt ttttcttgtt tcttctcagt tcatgtaaaa tagtaaacgg
     5221 gctatgctga atgtcgttgc caattatact aatagaaaat ccttcttcgt gaagcagaaa
     5281 gattctttct cgtttgagta tagtaagatg acaatactgg ctcataatta ttttccttct
     5341 aggagtgttc tcgacaaact tatactagtt ggatatcgat tatgactcat ttttatgtgt
     5401 tgcacttaaa gtgtaaattc aaggtataga aagaggttcc ctatgaaaaa atacctatta
     5461 caatcttaac tggctatctt ggttcaggaa aaacgatact tctaaatcat attctgtacg
     5521 gtgatcacgg aaaggaaatt gctgtcattg taaatgacat aggggaagta aatgttgatg
     5581 gggtattagt cgacaagaaa ggttttaaaa gaactggaga aaaacttgtt tcgatgccga
     5641 atggatgcat ttgttgtaca ttacgcgaag atttgattgt tgaactagat caattagtgc
     5701 aattttctga cttgaatcaa attgttattg aagcttcagg aatcagcaaa ccaattccaa
     5761 ttattcaagc aattatatta gctaaaaacc ctttagacat tgatttgacc caacgattag
     5821 agattggtgc cattattata gtagtggatg taaaacgttt ttgggataat ttcgaaacgg
     5881 gtgaaaagat tcaggaaaga aaagctgaag gtaatgtagt tgaagaagaa caggatattc
     5941 gtggcttgtt aattgatcaa ttcgagtgtt gtaacatatt acttttaaat aatagtgact
     6001 tagtgtcaac caagacgatt tacaaaatta acggtctaat tgctaagtta cagtccaatg
     6061 ccaaaataat taggacaatt aaaggtgaag tagacttatc gaaaattcta aatacaaatc
     6121 tttttaatat agatgagact tcctattcaa tgggctggtt caaagagtta gagcttggct
     6181 atcaaaatca tattcctgaa acagaagaat atggtatctc aagttttatc tatcgaaatc
     6241 ggttactcct tgacgcacaa aaatttgccc atcttacgga taaaaatttt cctggcaata
     6301 ttacaagagc aaaagggttt ctttggtttg cccaacatag tgatttttcg acgatctttg
     6361 aaacatcggg tagccataaa agtattgaat cattaaatta ttgggtagct agtttaccta
     6421 aaattgagtg tcaaatgatt atacaaaaaa acccgaattg aaggaagcct ggcatccgtt
     6481 gtttggtgaa cgcattaata aactagtttt tattggtatg aagatggatc aacaatgtat
     6541 taaggaacaa cttgagggtt gtttaactga ttctcttaat gcagataatt tccgaaaaat
     6601 ttcaccattt ccatggaaaa attctaatat gtttagccag atatcgttaa tgaaattttt
     6661 aagaaaagct ggtgtcaaga taggcgatgt cataattatt ggcattttga ttattccctc
     6721 ttttattccc ttatttgtat tctctataga aaaggagaat gaaacaactg aagatgctat
     6781 caaatatgcc atcgttcaaa ttgatggcaa ggaaatggat cgcttcgatt tggataagat
     6841 caatcataaa ctcgtgaatt atcatcctgc gaagggacaa tataatattg ttgagattaa
     6901 agatggaaga attcgagtta aagaagataa tagtcctgat caaatcgcgg ttagaactgg
     6961 atggatctca aaacccggtc aaacgagtat ttgtttaccc cataagttag ttattagtat
     7021 tgagaaaaaa gaaagcaaag attactacat ttactaatct ggaaatagat gaggaggttt
     7081 ttaataagaa aaagatatta ttattaataa tagcaggggc tttattaagt gtgttaagcg
     7141 cttgtggaca agaaaaagaa gcggtgacaa caggcacaag tatctttaac gggacctgca
     7201 atggtttagt taacagtcgg ttagattact tattttggct cttcgtcaat gagtgttggt
     7261 gaagaaattc aatagaataa tcgagatact cacacggcta gacagctatc ttgtctagcc
     7321 gtgttgttgt tctggcttta gtcagttggg tagtgttctt agttttcttg aaatattttc
     7381 ctcgatataa aaagattcgt tctcggtagt tttgaaagtt tctaaagcca taggcaattc
     7441 gttttagtac tttgatatgg ttgttcaaac attctatagg gccgttggaa tagggaactc
     7501 gcaacgctcg tttgatttct gttcgatatt tcttgaaggt cgtgaacact ggttgatagt
     7561 gctctggcaa ctccttgtag tcttctttta ggagcgcgac gaattcagga acatcttgtc
     7621 ttctgatagc ggaaagaaaa acctggtaga cttcgtagcc tcgctttaag gagtcatcat
     7681 aatataatag ccgatcgact atctccgctt ctgtcagatg atctcgaaat gacggacgcc
     7741 agtagcgatg ctgaccattc aattcccacg cattcttttg aagtagtctc cagtatttct
     7801 ttaagtgctt cgaccgacga tccccttttt taaaggtctt cattacttga attcggtggt
     7861 tggtaaaggc ccgaccgatg tgttggctaa tatgaaagcg atcggcgacg attcgggcat
     7921 tcggaaaaca ctctttcacc aatgtgcgat agggtgtata gaaatctgaa accactagac
     7981 gtacttgttc acggactttt ctagggtagc gcaagaaata gtcgcgtaaa ggattgagtt
     8041 gccgattttc cacaatatca atcagttgat gggtcttgcc gtccatcatg acaaagctca
     8101 tggctcccga gacgtttttc accgatttga attcatcgaa acacaccact tctggtaacg
     8161 gctggttcaa agaaacggtt ttaggccgaa ggctgcgaag tattcgaatg acagtggtcg
     8221 gagaaatgtg cttcatacgt gcaatcaaag acatagaaat aggctcactt aatagctcaa
     8281 gaatggcttg tttgactctg cgggcaatgg agcagcgacg atcgctaact gaatcttctg
     8341 ctaaaaaagt ctttccacag tgtttacatt tgaagcgctg tttgttaatc cgcacaatgg
     8401 tcttgtagtt actgacatca ttcaataaga tggatacttt tttccagccc catttaatga
     8461 tcgtttgctt attttgatag tggcaatgga agcattcctc tggttgatag gtcaatgtgc
     8521 catcaaaaac aaaacatgtt tcgtcattaa tgcgctcttt gcgaaaggca tcttcatgaa
     8581 aggtaagatt taggtctaga atatctagta actctttggt aaactctgaa taggacatct
     8641 tgaaacactc ctttgaatgg ttttcgtcga ctttattcta aaggatttca aggtgtctgt
     8701 ttgcgtttat tagaaaaaag aaaaagtatt ggcaacagaa ggcgtcacca acactagata
     8761 ttatagatcc cttattttct tcgcttcaaa ttgtcaagga gtcatcataa attttgtatg
     8821 gattcttttg tttgggtagt agtcttctaa ataatcttgg attaacacct tcatctctat
     8881 tttactttta tatttgttgg agtcgattaa ttctcatttg attgatcgat gaaacgcttc
     8941 aattactgca ttgtcaacag gagtcccagt ttggctcatt gaatgtgtga tgtggtggtc
     9001 ggtcaacagc tcttgataaa taaaagaccg atgctggcta cctctatcgg aatgaattac
     9061 cgtaggcaat tctccttaat aaatttgtaa tggacggacg acaatctctt ttttcatgtg
     9121 tgaatccacc atatagtaac gtagaatacg agttgctaag tcaatatagg tggacaaata
     9181 gaggcgaccg tcattacatg gaatgtaagt aatatccgtc acccaaacag catcaatttg
     9241 gttctgttca aattatcgat tcaacatttt ttttaccatt tctttgattg ttttttctct
     9301 accatgagaa gatttgcgtc gatgaaatcc tcttgtgcat aaattcattt cacgcataag
     9361 aacagctaca acacgtttat tgatttcgat tccttcatcg taaagttttt gagtgatccc
     9421 tggagatccg tatcgatctt tgtgttcgta gaacactcgt cttcctcttt tagtcgttta
     9481 ttttcctgtt caagaatgta gaaatctgct ttatcaggta atctttttcc ttgtccagca
     9541 aaagcatttt tcccgtatcg acgatattct gaaacccatc gggaaattgt tggacgagag
     9601 atattgtatt cttcagcaat tttcttggta gttacttttt tctcaaggat atcctgtgaa
     9661 atctttagtt taaatttacg atcatatgtt tttttcaata gagttcattc cttccggtaa
     9721 cgtaactgat agtcaagaaa agtgtatcat agcccaactt agtatcaggg tttgtcaact
     9781 aaactgtgga agttgataga taagagtttt taacaaccaa aattctcttg actatttttg
     9841 aaatcagaca aattttgatt ggacacatag ttgaataaat ctaccgtcgt tacggaaggt
     9901 aaatcgcatg cttttcaatt ctagaggaga agtcctcgtt gaagtaccat ggcccagttc
     9961 tggattcgac ctcctgccca cttcgtacgt aaataaagta attttaggag tgagactgtg
    10021 acaaaagtta tttttaagct aaaaacgaat taaaaaacgt taataattaa aatcattcgt
    10081 tttagattct atgaatcatt atagaacgct gtaaaatcga tactttataa ttataaagaa
    10141 gatggcttca aatttattgt tcgaaatttg aaactatctt tttacttatg tcacagactc
    10201 ccttagttga gttattcttt aatttcgaat ttcgagatag ctagatatat tgcaagcata
    10261 cattcttgat aacaatcttg atcatatttt ccagttctcc aggattgctt atggaccaaa
    10321 gcgctaaatc ttttgagaat ggccacaact gcttcttcat ttccattctt tgctaaaatg
    10381 aaatcttctt ttaaagtatt cataaattta ccttcttccc atgaacttat aatctattta
    10441 tttttttggg aaggaggagg acgagcaaag aagcatacaa aattagttat tatgcagata
    10501 ttaaaccagc attttttgaa tttttttgta aagtcgatgt tttaaatttg tcgcaccctg
    10561 tcttgtaata cccagaacct ttccaatttc tttatcagtt ttattaaaga taaatttttc
    10621 gataagaaaa atttgttcag gttctttcaa caaaggaagg atttttgcta attttatatc
    10681 ttcaacaagg agagtcacat ttaaaacatt aatcggttgt ttaaatttta tagtatcttt
    10741 agtaaacaaa tatggtggga gttgatcaag ttgttcatgt ttttgaattt cttcttgttt
    10801 tttataataa gtattagcgg tgttcaaaat gaccttttca aagaatcgaa tcaactgggc
    10861 atttacgcgt tcgtcgttat ctgacatatt gcacacctcc tccattaaga tttaaaggga
    10921 aaagaggcaa aaaacacgaa aagaagctaa tgcaattatg ctgcgctgcg aataacttct
    10981 ataagctcac atgcattgat aggactgctg atgtttattt tcaaaaatgt ttttttagtt
    11041 gataatggat agttatcttt atacttagaa aagaaaattc atatatcttc ttaaatatca
    11101 aacatgtcct tatggctaag aaaatgtctt gagcttttta cgtataataa atcttttcta
    11161 aaacctcctt ttggataata ttcttattcg tgtatagatt gtatttttta tttcttcccc
    11221 cttcataatt aacaactaga aaagagttcg aatagacacg tatttgaacg aaaattttta
    11281 ttggattccc aaattggagt atttagaaac gaaaaattcc tattatctgt atagtgctta
    11341 gataataacg gatcataata attattgtct ttgaactaga tatatgtaaa tagtattcat
    11401 catgatgaaa aatgatgagt tctcggtgat aaaatgtact ttttacggtg gaatatacat
    11461 gaaagcgata agtggatatt ttataatgaa gtaagttagc ttattttgac agaggaatag
    11521 tattttagat aacgtataaa atactattta atgatgtaga aaggaaagag agaaacaaaa
    11581 gtgttttcag ataaagaagt cttattaaag tctcttcatg tttgtttaaa
//
LOCUS       DACDLM010000083        11615 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.085, whole genome shotgun sequence.
ACCESSION   DACDLM010000083 DACDLM010000000
VERSION     DACDLM010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.085"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(125..1285)
                     /locus_tag="IV356_002405"
     CDS             complement(125..1285)
                     /locus_tag="IV356_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAP9016055.1"
                     /translation="MSKGKHRKKQKISISFLVILLLSVSFFSTGIIIGGQLTKIPHSQ
                     TYKAEPTQLTSNLTPDEQRLASKIDQLLQKSDYIGSIYVRKNNRVLLEKGYGYANLRV
                     KESNSPSIYYQIGSIQKAMTALLILKQIQAGKLTFDTKLAEFYPQIPGSQQITIKNML
                     YMRSGLHRTASPDKPMSDSEIIQFALHHLKLTDYDTYHYEPLNYTLLTGILIKLTNQP
                     YETLLKKEIIRPLHLEHTDFYDNVKNSPQHAVSYQMSATDDYSKALIEPETDIRNELG
                     TGNISMSVYDLNKFFTSVLSGGIIPKELLFSLWQNNGDKHPYSGGVYSGNDYILAQGN
                     INRFHAVVAMKKDTKDAIVMESNIQSDKNIKLPATDLRNQIYELMEGVHLSN"
     gene            1450..2625
                     /gene="mltG"
                     /locus_tag="IV356_002406"
     CDS             1450..2625
                     /gene="mltG"
                     /locus_tag="IV356_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HAP9016056.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELYQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVQKYVNNS"
     gene            2761..3240
                     /gene="greA"
                     /locus_tag="IV356_002407"
     CDS             2761..3240
                     /gene="greA"
                     /locus_tag="IV356_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HAP9016057.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGD
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            3408..4139
                     /locus_tag="IV356_002408"
     CDS             3408..4139
                     /locus_tag="IV356_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HAP9016058.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKYPRTKFQNFQLILGSLVIFFSLVNSPALWMMVVLAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMVQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAIISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKICSS
                     DYDENPRRLKIITNTLVGDVEVIRI"
     gene            4136..5203
                     /locus_tag="IV356_002409"
     CDS             4136..5203
                     /locus_tag="IV356_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP9016059.1"
                     /translation="MMGRISKAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLMAISLGVGLIVFLLLSLIQKAKYGKIEEKLRALSSGNYESKLLHQP
                     IPSASDDLYIKDIDMEITKIKEKMIEVSSELQIMTSRPQYVDGQTKEEILKLERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWEVEDVKLTSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVETKVPLMKEA"
     gene            5210..5842
                     /locus_tag="IV356_002410"
     CDS             5210..5842
                     /locus_tag="IV356_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP9016060.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     ALRPDVILMDLVMEEMDGIESTKAILKDWPKAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNDPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            5982..6647
                     /locus_tag="IV356_002411"
     CDS             5982..6647
                     /locus_tag="IV356_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HAP9016061.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            6675..6968
                     /locus_tag="IV356_002412"
     CDS             6675..6968
                     /locus_tag="IV356_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HAP9016062.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEMDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(7036..7983)
                     /locus_tag="IV356_002413"
     CDS             complement(7036..7983)
                     /locus_tag="IV356_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAP9016063.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(8161..8964)
                     /locus_tag="IV356_002414"
     CDS             complement(8161..8964)
                     /locus_tag="IV356_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HAP9016064.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            9110..10024
                     /locus_tag="IV356_002415"
     CDS             9110..10024
                     /locus_tag="IV356_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAP9016065.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKNVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            10072..10542
                     /locus_tag="IV356_002416"
     CDS             10072..10542
                     /locus_tag="IV356_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HAP9016066.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            10627..11235
                     /locus_tag="IV356_002417"
     CDS             10627..11235
                     /locus_tag="IV356_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HAP9016067.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNAAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            11369..11569
                     /locus_tag="IV356_002418"
     CDS             11369..11569
                     /locus_tag="IV356_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP9016068.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
BASE COUNT         3900 a         1800 c         2376 g         3539 t
ORIGIN      
        1 taaaataaga aataaattaa caaataataa ggacagataa tatttgttaa tttatttcta
       61 cttttcagat agagtactaa ctaaattgac tatacagaga tgacaactaa tattatgtca
      121 aaatttaatt tgataagtga acaccttcca tcagttcata aatctgattt cttaaatcag
      181 tggccggcaa tttgatgttc ttatccgatt ggatattact ttccatgacg attgcatctt
      241 tagtgtcttt tttcatcgcc actactgcat ggaatcgatt gatattcccc tgagcaagga
      301 tataatcgtt tccactgtaa acaccgccgc tgtaaggatg tttatcacca ttattttgcc
      361 acaatgagaa aagtagttct tttggtatga taccgccaga aagaacactg gtaaagaatt
      421 tgttcaagtc ataaacagac atacttatgt ttcctgtacc taattcattt cggatgtcgg
      481 tttcaggctc gatcaatgct tttgaataat cgtcagttgc agacatctgg taagatacag
      541 catgttgagg cgaatttttt acattgtcat aaaaatctgt atgttctaga tggagtggac
      601 gaatgatttc tttttttaga agagtttcat aaggctgatt cgttagtttg atcaatatcc
      661 ctgtaagcaa tgtataattc aatggttcat aatgatacgt atcataatca gtaagtttca
      721 aatgatgaag ggcgaactga atgatttcac tatccgacat aggtttgtcg ggagaagcag
      781 ttcgatgaag accagagcgc atataaagca tatttttgat tgtgatttgc tgacttccag
      841 gaatctgagg ataaaattct gctaactttg tgtcaaaagt taacttacca gcttggattt
      901 gttttagtat cagtaaagca gtcattgctt tttgaatcga accgatttga tagtaaatag
      961 aaggtgaatt cgattctttt acgcgcagat ttgcatatcc atatcctttt tctaatagta
     1021 cgcgattatt tttgcgaaca taaatcgaac cgatataatc tgatttttgt agtaattgat
     1081 caattttgct agcaagcctc tgctcatcgg gcgttaaatt ggaagtaagt tgtgttggct
     1141 ccgctttata agtttgggaa tgaggtattt ttgttaattg acctcctata atgatgcctg
     1201 ttgaaaagaa gctgacagac aataataaaa ttacaagaaa agaaatagaa attttttgtt
     1261 tttttcgatg ttttcctttt gacatgttaa ttcctttcta tccattttta actatttttc
     1321 attgtaatcc tcaaaaagag tatttgccac ttacaatttt gacataatat ttggtaaaat
     1381 aattcacggc agtagaaatt tcatgtataa taaacagagt tacgaagatg atagtaagga
     1441 ggagttgttt tgtcaggaaa caaacaacac ccaagtaaag ataaaaaaga agccagtaag
     1501 gcagctacag cagatataat cgacaagcgg agaaatctgc gtaaaaaaga agataagatt
     1561 gtgaggaaga tcattttagt gattgctctt acattattaa ttattggcgg atttcttgga
     1621 tttaccgtgt atcgttatgt agatagcggg ttgaagcctt tagataaatc agatgaccaa
     1681 ttagtccaag tggagatccc gagtggctct tctaacaagc agattggtga gattttggag
     1741 aaggacaata ttattaaaag cgggattgtt ttcaattatt atacaaaatt taaaaattta
     1801 actggctttc aagctggcta ttatcagtta gcgcctaata tgactcttga cgagattggc
     1861 aaacagctgc aagaaggcgg cacttctgag ccaacaaaag ttgcagatgg gaaaattgcc
     1921 attccagaag gctacgacat cgatcagatt gctgagcggg tagcgaaggt aactggtaaa
     1981 gacaagaaag aatttttaga tttagtaaat gatgagactt tctttaacga gttgtatcaa
     2041 aaattcccag aattgttgga aagtgcctct aaagctgaga acacaaaata ccgtttggaa
     2101 ggctacttat tcccagctac ttatgattac tacacgagta cttcgcttaa ggatcttgtg
     2161 attgagatgg tgaacaaaac aaatacggtc atgcaaaact attattcagc tatcaaacag
     2221 aaaaatttga ctgtacaaga agttttaact ttggcttctc tagttgaaaa agaaggcgta
     2281 aaagaaaatg atcgtaaaaa tattgcacaa gtcttcttta accgaatcaa ggcaaatatg
     2341 ccacttcagt cagatatctc tgttttatat gcattaggag aacataaaga attggtgacg
     2401 tatgaagata cagctgtaga ttcaccatac aatttgtata ccaataccgg ctatgggcct
     2461 ggtccttttg acaatccaag cgaagaggca atcaaggcag tattagaacc agcagaaaat
     2521 gactattatt atttcgtagc agatacgagc actggaaatg tttatttcgc taaaacgtat
     2581 gaagaacata tggaactagt gcaaaaatat gtaaataatt cttagaaaaa caggggctag
     2641 tcattgatca tttttagaaa aacatttaca ttttaagaaa agcgtggtaa tcttttttgg
     2701 actatattcc tcaaaagatt accttttgcg gtattttatc gaaaaaagga gacgttacac
     2761 atggtagaga aagtttatcc aatgactcta gaaggtaaag aaaaattaga aaaagaatta
     2821 gaagaactaa aaacagttaa acgcggagaa atcattgaac gaatcaaaat cgctcgcggt
     2881 ttcggagatc tttccgaaaa ctccgaatac gaatcagcta aagatgaaca agcatttgtt
     2941 gaaggaagaa tcacaacaat tgaaaatatg atccgttttg cacaaatcat cgataatgac
     3001 ggcgtagatg cagatgaggt atcgatcggt aaaacagtta cgttcatcga gttgcctgat
     3061 ggagatgaag aagagtacac gattgtcgga agtgctgaag cagacccgtt ttctggaaag
     3121 atttccaatg attctcctat cgcgcaagca ttgattggca aacgtaaaaa tgatgaagta
     3181 accattgcta caccaggtgg cgatatgtta gttaaaatcg tcaaagtaga acaagcgtag
     3241 tctgactgaa agatctagag agttcatctt actgatgacg cactctagat cttttctctt
     3301 tgagtattgc aggtttcact gaacgatctt acatctaaag tcctatagcc aacagtcaaa
     3361 aaaataggta tgatgaaatg agaatgtgtc aggagggaga aaaagcgatg aatagttctt
     3421 ggcgtttttt tgtggtagtc gaagcactgc tgctgttatt tgctgtttgg caaatcgtaa
     3481 acaatactgg acttttgctt ttagtaatat tcggtatttt caatatatat ctagctatgc
     3541 gcaaatatcc tcgtactaaa tttcaaaatt ttcaattgat cttagggagc ttggtcattt
     3601 tttttagctt agtcaacagt cctgctttat ggatgatggt tgtattggcc gttttattta
     3661 tcgggctgaa aggtgtagag atttcaggaa tagatttgac aaaaaatgct ttttggcgaa
     3721 aaaaacagat catgatggtc caaacagagc aattaaaaac acataataat gagcgtaaaa
     3781 gacagcaatt atttggtaac caacgtattg gaaacgacgt ctatgaatgg gatgatatca
     3841 acattgccat catttctggt gatactatca tcgatttggg caatacactt ttgccaaaag
     3901 atgataatat tgtgattgta agaaaaggga taggcagaac acggatctta gtacccctgg
     3961 gagtggctat tcgtttagag catgcgacat tagtaggaaa tgtcttgttt gaagaagagc
     4021 agttttcctt aaaaaacgaa cagatcaaaa tctgcagcag tgattatgat gaaaatcctc
     4081 gcagattgaa gatcattacc aatactttgg ttggagatgt cgaggtgata cgaatatgat
     4141 gggaagaata tccaaagcaa tgctagctgt ttattcgggg attgcggctt tccttattat
     4201 tctattttca cttttcactt atttttatgc cagtaaccaa agtcattggt ggggagaatt
     4261 gctgcgtgcg cgtttattat acgttccgct tatcttccat ttgatggcaa tttcattagg
     4321 tgtaggattg atcgtatttc tattgttatc acttattcaa aaggcaaaat acgggaaaat
     4381 cgaagaaaag cttcgtgcac tttcttctgg caattatgaa tccaaacttt tgcatcagcc
     4441 gatcccaagc gcgtcggatg atctgtacat caaagatatt gatatggaaa ttactaaaat
     4501 aaaagaaaaa atgatcgaag tatccagtga attacagatt atgactagcc gtcctcaata
     4561 tgtagatgga caaaccaaag aagagatttt aaaattagaa aggcatcgat tagctcgtga
     4621 gcttcatgat tcagtttcac agcaattatt tgcagcgatg atgatgatgt cggcattgac
     4681 ggagcaagca gaaaaaagtg agacaccaga aatgttccgt aagcagttga aaatggtggc
     4741 agagatcatc aacgcttccc agtctgagat gcgtgcgctg cttcttcatc tgcgtccagt
     4801 caatttagaa gaaaaaagtt taaaacaagg cattgagcag ttattgaagg aattgcagaa
     4861 taaaatccag atttcgctaa aatgggaggt agaagatgta aaattaacta gttccattga
     4921 ggatcacttg ttccgaatcg ttcaagaatt gttatcaaac acattaagac atgctaaggc
     4981 taatgaatta gaagtctatt tgcataaaat agataacaat cttttattac gtatcattga
     5041 cgacgggaca ggatttaata tgaatgaaac caaaacggga agttatggat tgaacaatat
     5101 caaagaacga gtagctggta ttggtggaac agtaaaaatc attagtttta aagggcaagg
     5161 tacgagcgtg gagaccaagg tccctttgat gaaggaggca tagataaaga tgataaaagt
     5221 tttattagta gatgaccatg aaatggtacg cttaggcgtc tcttcttatt tatctatcca
     5281 agaagacatt gaagtgattg gagaagctga aaatggacgt caaggctatg aaaaggcgat
     5341 ggcacttcga ccggatgtca ttttaatgga tctagtcatg gaagaaatgg atggcatcga
     5401 atcaacaaaa gcaatcttaa aagattggcc aaaagccaaa atcattatcg tcacaagttt
     5461 tattgatgat gaaaaagttt atcctgcaat tgaagcagga gcagcaggat atttgttgaa
     5521 gacgtctaca gcacatgaaa tagctgatgc tataagggct acgcaacgcg gcgagcgagt
     5581 actagaacct gaagtgacaa caaaaatgat ggaaaaaatg agtcggcgaa atgatccagt
     5641 attgcatgaa gaattaacga atcgagaaaa tgaaattttg atgctgattt ctgaagggaa
     5701 aagtaatcag gaaatcgcgg atgaattgtt tatcacactg aaaacagtca aaacgcatgt
     5761 gtcgaatata ttagctaagt tagaggtaga agaccgaact caagcagcta tctatgcgtt
     5821 taaacatggt ttggtgaaat aaaaacgatg ataaagagga taatcaaaag ctgagaaaat
     5881 aactattatt tttcttggct tttttacaat aatgatgctt gcttttgttt ttggaaaggc
     5941 tttgttatac tgagaaaaga agatactaaa ggaggaaaat ggtgaaacaa aattttgcaa
     6001 ttgtaggcct tggacgattt ggcggaagca tctgccgtac actgatcgaa gctggacaag
     6061 aagtactggc tattgacagt aatgaagatc gagtcaatga atatatgaat atagccaccc
     6121 atgctgttgt ggcaaatgca caggatgaga tgacacttcg ttcattaggt ataagaaatt
     6181 tcgatcatgt aattgtcgct attggagaag atatccaagc cagcatctta gttactctga
     6241 tggtaaagga aatgggcgta ccgaatattt tagcaaaagc ccaaaatgag taccatgccc
     6301 gtgtactaga gaagatcgga gcagatcgtg tcgtacaccc tgagcgagac atggggatac
     6361 ggattgcaca taacttagta tcaaagaata ttctagacta cttagagctg tcagataaat
     6421 attctttagc agaaatccga gtctccaatc ctaaattttt caacaaaaca ttagctgaat
     6481 taaatttcag gcaacgtttt gacttaacag tagtcgccat acgaagagta gatcaaacgg
     6541 ttatcgcttc tcctgcagca gatgaatatg ttcgtgaaaa tgataatcta ctggttattg
     6601 gagagacagg cgatgtggat attctagacg ataagatgaa tcaatagaaa gaaaagagaa
     6661 agtaggttgt tgggatgaaa ttaacggtaa cgccaaaagc acaaaaatgg tttgactcag
     6721 aaattgatct gccagaaact tacggaatac gtttttttgg aaaagtctac ggcaaaacag
     6781 aggttcatga tggtttttcg attggaatgt cagttgaaca gccagaacat cctgtaaaga
     6841 aagtggaaat ggatgggaca ctttttttta tcgaggaagc agatgaatgg ttctttaaag
     6901 gatatgattt acttgttgat tatgatccca acctggagga gccaacctat cactttaaaa
     6961 aacaataaaa aaagagaggg tgacacaatt tttgtcacct tctctttttt cttttgaaaa
     7021 tattgttttc agctattaat atcctgcaga caattttact tgattggttt gaagctcatg
     7081 ggtggcaaag tagcttttca gattggttaa aaaaatagcc attaatttct tttgaaaatc
     7141 aggtgtcaaa cctgcaatgt gggaagtaat cagtacattg tccattttcc aaagaggatg
     7201 atcttgtgga agaggctctt cctcaaaaac gtctaatgct gcaaaggaaa gttgctggtt
     7261 atttaaagcc tgcaccagat cttgtgtctt aacagaagca ccacggccaa cattgatgaa
     7321 tacagatttt ggatcaaagt gttcaaacat atgctgatca aagagcccag ttgtttcctc
     7381 cgttagaggt aagatattga ctacgaaatc tacttcagga agaacttcct ttagttgatt
     7441 taaagaaaaa gtcttttcca ttccttctgc tggatgaccg gatgtattga ttccatagca
     7501 gttcatgtct aatgctttgc atttttttgc aatcattttt ccaatatggc cagttccaat
     7561 gattagtatt tttttccctt ggatagattg gtaatggacc gatgaaccta accatttcat
     7621 gtcactctgt gccttttgtg cttgaaaaag accacgagaa tacccaagga tgattcctaa
     7681 gacatgctcc gtaatcgatt cactgtggat gccactacca tttgaaagta aaatatgttt
     7741 ctttgaaaaa gtctcaaggg gtagctgatc aacaccagct gagatagatt ggacccattt
     7801 caaggtagaa gaggctaata gtttttcttg gtagtctgag ttccagccca aactgatctc
     7861 tacattttgt agatcctctg gttgtaattc tgttttaaag atataaccag gcgctatagt
     7921 atggatttct tcgataaatt catcacgaaa tggacgatct gcataaatga ttctttctga
     7981 catagttaat ttcccgcctt tctttactct aagtgtagcg catacaagaa gaactttgaa
     8041 gcgccttgct tgttttttga gaaagaaata tttttcaaat aaaaaagggg ctgtgacaaa
     8101 aaaatgtcac aacctctaaa agggtctatt taagtagaaa taacgagttg tctttatttc
     8161 ttaattgatc gatatttttg cccatccttt gacagcttga gcaaaaataa agattcctgc
     8221 aaaagcaatg aaggcgctag tgtcaaaaga aggaagaaag accatcaaga ttgttgcaat
     8281 tatagtaggc aatgaaattg aatagatcaa tgtttttaaa caatcaagaa aagtagcttt
     8341 tgttagtcga aagcgtgcat agagaaaagc agcaatgttg gtaaatagca aagtgatcag
     8401 cagattcaga aaactaggat aaatagaaaa tataaatgtc aggactttta tccaaagtgg
     8461 tatagatgct tcacttaaaa aagaacggag ctgcttacct gttaagtttt ttaaagattc
     8521 attggtgtag ggaagttcta attggttatt gttcaacaaa gcagaagtcg tgcctgtatt
     8581 aggaagagct atgataagtt tgttttttaa catcccgaca ctaacaaaat tccccatcaa
     8641 atcagtagag atgtcctgtt ctgttcgttt tccctctgga tcaaatgtga agataatgga
     8701 gtttgtttgg taaatgaatc cttctttttc ttcggtttga agctgcccgt tttggattgt
     8761 aaaatcagga atgcgagtag caatcttttg cccatccaat tgaatgttat ttaagacttg
     8821 aaaaacttga aaagagattg gcaaagccat aattatactc aaaactaaaa gatagacaat
     8881 ggctttccaa aatgggacat ttctcgcctc ctttaggtct ttgaatcgta taaaggaact
     8941 gataattaat tgttttgttg tcataagtac tcctcatcta gtagtgtcat cacttgcaat
     9001 tctagcgaag tatcaagtga aatacaagtg ctttagggaa acatctgaat gattggtgaa
     9061 atatcaaaaa aatgttattc ttgtctaaag actatccaat ataaataaaa tggaggaagg
     9121 aatagtgcct acacagccac agagatcatc aaaaaaacta tttggagtag tggttttgaa
     9181 tgcggtgatc actttatcag aatttattgg agggattatg tcagggagtt tgtctcttgt
     9241 ttcagatgct ttccataacc ttagtgatac attggcaatt attttttctt acggggcaca
     9301 aaaaatggcc cgaaaagaag caaataaaaa acgtacgtat ggctaccagc gtttagaaat
     9361 attgagtgct ttcatcaact cattcatatt gatcatatta tccttgtttt taaccgttga
     9421 agcattcaag cggttcactt caccagaaaa gataaatagt catttgatgc taacagtagc
     9481 agttattgga ttgctcgcga atttgttctc agtattatta ttacgacaag aagcagatga
     9541 aagtttgaat ataaaatcta gttatttgca tttgttaagt gatacactgt cttcggtaag
     9601 tgtgattatc ggagcaattt tgatccgttt tttcgatatc tactggatcg atccagttat
     9661 tacactgatc atttcgatat atatattgat agaagcgata atggtgatca aaaaagctgc
     9721 cgctattttg atacaaagtg cacctgctat tgactatgaa aaaatggaac aagaaattga
     9781 agcaatcgat ggggtaaaga atgttcatca tgtccatatt tggcagtata gcgaaaagat
     9841 aattattttc gacggacata ttgattttga agatcagcta ctaagcgaga ttgaaaagat
     9901 atatcctcgt ataatttctt tattaaaatt aaaatatggt attacacatg tgacgatcca
     9961 agcagagaca aaggcaaagg atcaaaaaaa attaattttt ttaaataaag atgaaagtta
    10021 ttgaaatata gagtatgata aataagaatt tttaataagg taggttggct catgaagcag
    10081 tatcgacagt taaaaggata tttagaagca aaaggatatt gggagatact agtctatctc
    10141 ttttttggtg gtttggctac gattgtaaat tttgttagtt ttgctctcgc acgccaatat
    10201 tttgatttaa gtatggcctt atccaattct atttcgtggt tttgttctgt attgtttgct
    10261 tttgtaacga acaaactttg ggtattccat tcaaaatcac cgaattttac acatgcactt
    10321 attgaatgcg gtaagttctt cttctaccgt atcctttctt acggattgga catgggggca
    10381 atggtattgt tgatcaatgt tatgaacagc aatgagtatg tggcgaaaat catcactcaa
    10441 attattgtta tcctagcgaa ctatattttc agcaagttgt ttatttttaa agaaactgag
    10501 gtttttgaag aagaagtagg tcaaagtgaa aaagacgact aggcataaca attgaagaat
    10561 ttccttctct ttgttactct ttgtaatgta gacattataa agaaaacatt gaggaggaat
    10621 ttttttatga cttacacatt accagatcta ccttatgcat atgacgcatt ggaaccttat
    10681 attgacgaag aaacgatgca tctgcatcat gataagcatc acaatactta tgtgacgaat
    10741 ttaaatgcag caattgagaa atacccagaa ttaggcgaaa aaacaataga agaattatta
    10801 tctgatatgg acgctattcc aacagatatc aagacagctg tacgtaacaa tggtggcgga
    10861 catgctaacc attcattttt ctgggaaatc atggcaccaa atgctggtgg cgaacctaca
    10921 ggagaaataa aagaagcgat taatgaagct tttggtgatt tttcttcttt taaagaagaa
    10981 ttcaaaaaag cagccgctgg acgatttggt tctggatggg cttggcttgt aatggaaaat
    11041 ggaaaattag ctattacctc tactgcaaat caagattctc cattgatgga aggaaagaca
    11101 ccaattctag gtttggacgt ttgggaacat gcttattatt tgaaatataa aaatgtccga
    11161 ccagattata ttgcagcatt ctggaatgtt attaattggg atgaagtaaa caaacgtttc
    11221 gaagcagcaa aataaccatt tcctccgtca tatcagtctt aaaaataatt tggaaaataa
    11281 aagagcgaaa gcttgctagc gttttctaaa ttgggtataa tgttcttgca aggttacttg
    11341 caagaacttt tttggaggat atacatttat ggaacacgga acggttaaat ggttcaacaa
    11401 tgaaaaagga tttgggttta ttacagtaga cggcggagat gacgtatttg ttcatttctc
    11461 agcaattcaa ggagacggct tcaagagcct agaagaaggt caagaagtag aattcacgat
    11521 tgttgaaggt gcacgcggac ctcaagctgc tgaagtgact aaattataat aatttgttga
    11581 ataaagacac gacttcttag agagtcgtgt ctttt
//
LOCUS       DACDLM010000084        11378 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.086, whole genome shotgun sequence.
ACCESSION   DACDLM010000084 DACDLM010000000
VERSION     DACDLM010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11378
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.086"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            81..644
                     /locus_tag="IV356_002419"
     CDS             81..644
                     /locus_tag="IV356_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016069.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(705..1070)
                     /locus_tag="IV356_002420"
     CDS             complement(705..1070)
                     /locus_tag="IV356_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016070.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(1146..1391)
                     /locus_tag="IV356_002421"
     CDS             complement(1146..1391)
                     /locus_tag="IV356_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP9016071.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(1461..1715)
                     /locus_tag="IV356_002422"
     CDS             complement(1461..1715)
                     /locus_tag="IV356_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016072.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(1879..2202)
                     /locus_tag="IV356_002423"
     CDS             complement(1879..2202)
                     /locus_tag="IV356_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016073.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            2389..2462
                     /locus_tag="IV356_002424"
     tRNA            2389..2462
                     /locus_tag="IV356_002424"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2423..2425,aa:Ile,seq:cat)
     gene            complement(2847..3344)
                     /locus_tag="IV356_002425"
     CDS             complement(2847..3344)
                     /locus_tag="IV356_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP9016074.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKAHQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(3384..4193)
                     /locus_tag="IV356_002426"
     CDS             complement(3384..4193)
                     /locus_tag="IV356_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP9016075.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            4527..5384
                     /locus_tag="IV356_002427"
     CDS             4527..5384
                     /locus_tag="IV356_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAP9016076.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            5377..6279
                     /locus_tag="IV356_002428"
     CDS             5377..6279
                     /locus_tag="IV356_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAP9016077.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            6312..6662
                     /locus_tag="IV356_002429"
     CDS             6312..6662
                     /locus_tag="IV356_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAP9016078.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            6696..7634
                     /locus_tag="IV356_002430"
     CDS             6696..7634
                     /locus_tag="IV356_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAP9016079.1"
                     /translation="MRYYFVDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPD
                     DIFVGTEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLI
                     TCIDRKTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAAR
                     KTTENEELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQ
                     RQTEKMIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTG
                     GLPGKSSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            7712..8605
                     /locus_tag="IV356_002431"
     CDS             7712..8605
                     /locus_tag="IV356_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP9016080.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            8643..9206
                     /gene="amaP"
                     /locus_tag="IV356_002432"
     CDS             8643..9206
                     /gene="amaP"
                     /locus_tag="IV356_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAP9016081.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            9219..9407
                     /locus_tag="IV356_002433"
     CDS             9219..9407
                     /locus_tag="IV356_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAP9016082.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            9420..10322
                     /locus_tag="IV356_002434"
     CDS             9420..10322
                     /locus_tag="IV356_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAP9016083.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            10354..10596
                     /locus_tag="IV356_002435"
     CDS             10354..10596
                     /locus_tag="IV356_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAP9016084.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(10852..11223)
                     /locus_tag="IV356_002436"
     CDS             complement(10852..11223)
                     /locus_tag="IV356_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016085.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         4026 a         1938 c         2150 g         3264 t
ORIGIN      
        1 ataacgtaat aattttttta ttttttgtgc tttcgccgtt attgtagagt gatttagcat
       61 tcttattttt aaaaataact gtgttatata ttaaaaaagg cataatagtt ataagctttt
      121 ttaaagaata tttagaaatt attaattttc gtctgaaaac aaaaaaagaa agcgttatta
      181 ttttagtcta ttttcagggg gggaacctta tgataaaaaa actattttta ctatcaatat
      241 taacgctagc aatggcaggt tgttctgact ctggcttagc aactgaactg atcacaaaat
      301 caactgaagc cacgacagag gagttaaaat gtggaaacga tcacagtgac tacagaggct
      361 taaatcgacg atgcatggga atattaggca gaagcaattg taagcatcga tgtagtaatc
      421 gaagaaggtg tagaagaagc aacagaaaaa tcaaaagaaa gatcaaaaga agcaatctgt
      481 gctgtgcatc gtatacagac gtcgaagatg cggtactttt aaaccacgtc aggagatgtt
      541 catttatgtc tagggaagtt ggcgatgaac caaaactaga gtacgctttt agttttgcac
      601 gtgaggatga agataaccct aaaacttacg acattttagc ttgatctaag atggttaaag
      661 ctttttaatg aagtaagagg agatagaagg cttttctagt tatattaggt aagataaatt
      721 cctttttgct ccaaatttgc taaacattct gctagataaa cttcatcgtg ttccggataa
      781 atcggcacgt tgcgctctac agtaggtaaa tcaaaaaatg cttcgcatga tttgccacga
      841 tacataggat ttttccactc tggtgctggg ctgtaaccac gtttttccat ttcatccatg
      901 acaagctgat gatattggaa taatctataa ggagaatagt gaaaaacata atccacagta
      961 gcatgtttct ttccccagcc atttcctctt aatgcacagc attcccgatg ttgtcctaaa
     1021 agctgttgac gaggaagctt tgaaatcaat ttttcatgcc ataatcgcat agaaatgtct
     1081 cctttatata tagattgtta accttagacg ttaaatgaaa aaaccagcac caaggctgga
     1141 aaaaatcact tcagtttgct tgctgtttct gagcgaccaa ttaggtaatc aacggaaata
     1201 tcgtaaaagt cagcgatata gattaattca atgatgcttg gaatttcttc tccttcttcg
     1261 tacttacgat atttgaataa aggaatactt aacgcgctag aaacagctac ttgagataaa
     1321 gatcggccag ttcttaagaa attcagacga caacgtaaag tatccagtaa aatagcttct
     1381 tcgatactca tttaatcacc tttcattata gtagaatagt tataatgact atagaaagct
     1441 acacatgcaa tcaatagtac tcaatgtttt ttatttaaac gtatcaaata aagaatgacg
     1501 atcaataaag acaaaaccag tcctgataat tcttctataa aaacactatc gggttcaaag
     1561 tagttgtaat taaaaacttt ccacataaag tagatagccg gaagagtcaa aatagctaaa
     1621 taaaaccgtt ctttgttcca attcataaga taaacaatac ttgcgaccag tgcgaccgca
     1681 ggcacccaaa acaaaactct caccaacgta atcatgtaac ggactcctca acgattcata
     1741 taataaaaga taacatgtta ttgcatacat cacaaatgaa atgctaggaa aataaaagaa
     1801 gaatagatca atgaaaaatg aaaaagcaga acagttttct gctgataagc aggaactgtt
     1861 ccgctgaatg tgtcttatct atcgagaaaa aatcaatgga ttgatatcta agtaattcaa
     1921 tacatataaa aagaggacga tcgcattcac taaaaaggaa agaatgatga tcccatagcg
     1981 aatggaaaca tatttaacaa atacttttgt ttgaatacgg gcatatcttt ttcctttata
     2041 gctgagcatc atgacaagaa gcaaaagggt aatcacacct tgaaaaatca ttccaataaa
     2101 cagaattcct gaggtttgat aatttaattg gagaaaataa gctgctgccg caactaaatc
     2161 gaataaaatc gcaataaatg gcaaaataat cactcctaac attgagaata aataaaagaa
     2221 taacattttt tctaaaataa gcaaataaaa attaaagtaa caaaatagtt atgacacaag
     2281 taaaagaaat aagaataaca atattatttt acttatattt tgaaacttgt gagagtttgt
     2341 cattcgtgct atagttgaaa agtaacaaaa ataaatttta tttatgatgt acctttagct
     2401 cagttggtta gagcagacgg ctcataaccg tccggtcgta ggttcgagtc ctacaaggta
     2461 cataagaggt tgtgaaaaag ctgccctgca tcaagtaata agaacagcca agtaaaaaca
     2521 gcttcttatg tttttacttg gctgttctta ttactgcaga tgcaagcttt tgaataccgt
     2581 ttaaggaaga ggttgtgaaa tcagcgtttt gacctgagta ttagcttaac aaacggaaaa
     2641 atagttcctc atattttgcc gtttgttaag ctaataccga gggtcagctg attgaacacc
     2701 atttaagaaa gaggtcgtga gcctgccgtt tcactctgtg tcataaaaaa gccaatctac
     2761 tttgatagaa aaagcacgta ggactaaaac agttctgcgt gcttttttta ttgtgtgtta
     2821 aatatcgtaa atgaagatag atatttttat gattcgacga tagagacgtt gaaatctttc
     2881 aacagctcta aagcggattc tccgtgtttt ctactggaga ctaacattgg atcaacaaaa
     2941 aagtctgctt caggaaaagc actctgcagg cctatcagat tagagagtac acacaagttt
     3001 gtttcaatcc cgactacttc gatctctttt tgttcttctt tgctttcaaa taaagtttcc
     3061 tggatttcag ctaaagtttc aggtggaatc gtaaagtaat actttttaat cactcgttca
     3121 ttttcttgtg gagaaagaag agggatcaat tgcaaatctt ctcgttcttc ttctttgtcc
     3181 ttcagttcaa ctggtatatc ccgtgtgaag agaatatatt cattattttg gtgtgcttta
     3241 gctaatcttt gagcaatacg ttctgccaat tgatctgact ctggaatata aaattcgctg
     3301 tttggatcaa gaatatgatt ttgcatatca ataataacta acattttctt tcctcctaca
     3361 ttcatatcgt cattttattc tttttaatag aagtttttta aaatataagc aacaccagct
     3421 tcttcattcg tcagtgttac ttggtttgca atttctttta cttgtcgctg tgcattcccc
     3481 atcgcaatac tcaacccgct gtaattcaac atagcaatgt cgttttcttg atcgccaaaa
     3541 gccatgatgt cactcgattc gattccaagg taatccgcca gaaaaacaag tgaatgagct
     3601 ttagtgatac ctgtaggcgt gatttctaag aaatgcggat cagagaatac tgattggata
     3661 ccatctgctt gcagatctct ttgtagcttc tgtagttttt cttcactctt atctgttaat
     3721 gctaatttaa gatagctaag agaaggatct tccaacatat ttaaaatttg atcaaaagaa
     3781 tggttctgta aattgaaatg ttcataataa gggtcatctt tgactagatt tgattcatcg
     3841 aatgtcagct gatcatcttg ggtttctcgg ctagcaatga tggatatttt cgcttcttga
     3901 gcatagaaga aggcttttct cagtgtatcg ctatctattt ttgaacgtct gagaactttc
     3961 gccatttttc catccttcat ttcagcaatc agtgaaccat tggaagaaat caaatagcca
     4021 ccgattccta attcggaaaa aatatcttta gcagaaatgc tgttccttcc ggtagcgacg
     4081 gttacgattc cgccattttc atcaaatttc cgaagtgctt ggatattttc ttctggtatc
     4141 tttccatttc gatcaagcaa ggtaccgtct aaatcaatcg ctgctagttt cattttatct
     4201 tcctactttc tttttacata tctattttcc tgttacctta agattaaatg agaatttaaa
     4261 aaaatgaaac taacttgctt tgtcattatg aattttttca aaaaacattc ttaagaaaaa
     4321 ggtggctata tatagtagtt tttggtcaat acctttgaat aaaaagccat gaaaaacgaa
     4381 tagttagcgc ttaccgatgc gttttgtgat aaaaaaattt taaaatattc aatgaaaaca
     4441 aagcatatat tttgctttaa aaccaaatga ggaatattct agatgtagaa caggttagaa
     4501 aaagattaga aaaaggagtg attttgatgg agaagagata cggcgtagtt cctgtggtaa
     4561 ctgcttcaga cgaaaattat gctccttact tgagcgtgat gatcgcaact gcattagaaa
     4621 attgcaataa aacaagacgc ataaaatttt atgtgattga cgatggtcta tcagaatata
     4681 gtaaagaagg attggaagaa acggtaaata aatattcaag taatgcaagt atccaattcc
     4741 tgacagtgga aaaagatatc tacgaagact tcctagtcag tgaccatatc acaactaccg
     4801 cttacttaag aatttcttta ccaaacttat tagctaaaga ggattataag aaagtccttt
     4861 acttagattc agatgtgtta gtactagacg atatcgtaaa actatatgat gagccgttaa
     4921 atggaaaaac aatcggcgct attatcgatc caggccaagt gaaagctttg gaaagattag
     4981 gaatcgattc cgatgacttg tacttcaatt caggagtgat ggtgattgac attgatcaat
     5041 ggaataaaaa agaaattaca gaaaaaacta tccattacct cagtgaaaat ggcgatcgaa
     5101 tcatctatca cgaccaagat gctttgaatg ctgtacttta tgaagattgg gaacaacttc
     5161 atccaaaatg gaacatgcag acttcgctga tatttgaacg tcatccagca ccaaatgaaa
     5221 aatatgaacg tcagtataaa gaaggaaatg aaaaaccttc gatcgttcac tttacaggac
     5281 atgataaacc ttggaatacg ttgaaagatc atccgtatac caatttatac ttaaaaaaat
     5341 tagcacacag tactctaacg aaagtaggcg agatcaatga ataaaaaaga aatagcagta
     5401 gtcgcaagtt gtaacacaaa attcgtacca catttagctg cattatttgt ctcagtatta
     5461 gataattgca acccgtctaa atttgttcgg ttctatgtga ttgacgatga tatcgatttt
     5521 gaaagtaaac agcttttacg cttctcagtg aaaaacgcac gaatgaactc agatgtggaa
     5581 ttcttgaaaa tcaataaaga attctttaca aatgtggtaa tcagcgatcg tattccagaa
     5641 acagcttatt atcgtattgc gattccggaa ttgttccgcg gcacagaagt tgaacgtatc
     5701 ttatatatgg attgcgacat gatcgcttta caagatatct ctaaattatg gcgtcttgac
     5761 ttcggtgatt caatcgtagc agctgttgaa gacgctgggt tccatcaacg actggaaaaa
     5821 atgaaaattt cagctaaatc aatgcgttat ttcaactcag gtttgatgct gatcaatgtg
     5881 aaaaaatggt tagatgaaaa tattacgcaa aaagtattag atttcatcga acataatcca
     5941 gaaaaattac gattccatga ccaagatgca ttaaatgcta tcttacatga ccgttggtta
     6001 ccacttcatc cgcgttggaa tgcacaaggc tatatcatgg caaaagcaaa aaaacatcca
     6061 acagcagcag gtgaacgtga atacgaagaa actcgcaaca atccttacat tatccatttt
     6121 tcaggacatg tgaaaccgtg gagcaaggat tttgaagggc caacgaagaa atattacgaa
     6181 aaatatgcag ggatgacggc tttccgttgt gtagctaaat tccctaaata tccaaaatat
     6241 gcaaaagttc aaccaaaaac agatgtagtt gttaaataat agaagacaac aactgaagag
     6301 ggggagtagg aatggaaatt acaatgtcta aaaatgcagt agagacgtta attgaaaagg
     6361 ttggggaaaa tacaaaaatc gcactcgcgc ttatcaatga ttccgatcca tttctaaggg
     6421 acaaaggtgc ttttgcaaaa ggcagctttt ttcaaatcat tccttttgtt tcggaatttg
     6481 gagaatatgc gactaaaatc gagcatccat tattggacat ctatacatct aaattagagc
     6541 aaaattattt cggtaaacga ttgaacatgg acttcaacaa acagcttgac agcttttcat
     6601 tagaaaatga aatcgcagta ctcgattata atatcaaatt aaagaactgc ttcttcagct
     6661 aatagtttcg agaaagtcca aaaaggaggt atacattgag atactacttt gtggatgaag
     6721 aaaagaatgt aatagaaaca gatgaaaaaa aatataattg gctcgtactt gatagtgcaa
     6781 agcccgaaga gattgagcaa gcaatcgaag aattcgagct tcctgatgat attttcgtag
     6841 gaaccgaata tccggaagaa gtttctcgga tggagcgcct ttatgagacg aaactagagc
     6901 atccattttc tttggtagtg attaatctag atcagtcaga taatcgtatc gaaaaaaaat
     6961 taacgccaat atcttttgta ctttccgata atctcttgat tacttgtatc gatagaaaaa
     7021 ccgaatttgt ggatcggctg ctgacaaagc atggaaatca tttaaactcg tttgaaaaga
     7081 tcatcacgta tacattatta gatatttaca cccattacgt gaaagaacta agagagatga
     7141 aaaagcgaat tgacgctttg gataaagcag ctcgtaaaac aacggaaaat gaagaactgt
     7201 ataaacaggc agatcttgaa agagacatcg tatatatcga tcatacctta agagatcaac
     7261 gggaaacaat ggatcaatta tggaattctg aaactttcat caaacgttta gacgatgaac
     7321 agctactcta tgatgtccat ttgagacagc gacaaacaga aaaaatgatc gagatctatc
     7381 gagatttatt agagagtatt ggtgatctat tcaacgggat gatggacaat aatctaaatc
     7441 atatcatgaa atatctagat tcagctgcat taatcatttc cgttccggcg ttgttcgcag
     7501 ggatttgggg aatgaataca ggaggattac cgggtaaaag ttctgctcta ggctttatac
     7561 tcgtagtctt tggctctttg atagcagcag tagttttagg ttaccattta taccggaaag
     7621 attatacaaa ttaaagaatc tatttaaaac aggtatcaaa caaagaaatt tgttttggca
     7681 atacaattta aaaactagga ggaatacagc aatgacagaa ccaaaattaa tcgacccgcg
     7741 aaacttgtac catacggaga aatttcctaa acaagatcag gatacaccag ctttacagca
     7801 gaatatgatt cctgttcctg attgtggaga agaatcctat gaaggcaata atcaactaga
     7861 aaaccgccgt gtactaatca ctggtggaga ttcagggatc ggtcgtgcag cagcgattgc
     7921 atttgctaga gaaggggcag atatcgctct tcaattcttc ccaggagaag aaaaagatgc
     7981 agaggaagta gcaaaatacg tgaaagatgc aggacgtaag attgtcttac taccttttga
     8041 tcttcgtgac gaacaagcac ctaaagaaat catagataaa gccgtgagtg aacttggcgg
     8101 gctagatacg atggtactaa acgcaggaca gcaaatttct tgtcagtcta ttgctgagtt
     8161 accacttgag caagtcaaag acacatttat gataaacatc atcgctatgt ttgctttagt
     8221 gaaagaagct gttccgcata tcccagcagg aggagcaatc gtaacaacaa cttctgttca
     8281 agcattcaat ccaagcgaac atttattaga ttacgcagca acaaaagctt caatcgctaa
     8341 ctttacgatc ggtttagcaa aacagcttgc acctaaagga atccgtgtaa atggtgtagc
     8401 acctggtcca atctggacac cattacaact agacgaagga caaccttctg attcgatccc
     8461 tgaatttggt cagcaaagtt tactagaacg tgcaggtcag ccaggagaat tagcaccagt
     8521 ttatgttttc ttagcatcga ataaagcaag ttatgttaca gcccaaattt acggagtaac
     8581 tggtggagaa gcgatcaact tataagaagt tgatcgtttc acccctatga ggaggtgcga
     8641 aaatgaataa aggtgtaaaa acgatcggag tgatcggaac attacttttg ctatctgtgc
     8701 ttttgtttgc gatactatta agtgcaacct atccattgcc ttttcagcta gagaagtttc
     8761 gattcttttc catcactaat tcatacgtgc aacaatatgt attttggctt gccgttgcat
     8821 ttgctatttt gacaattatc acgttacttg ttttcctgtt ttatccaaaa acaatcggaa
     8881 actttctact gaaacatggt gatggggagt tgacgttgga taaaaaagca attgaaggaa
     8941 tggttcgttc tcacttgcat gaagatgaat tcatccattc accaaaagta aatgtcaaag
     9001 caacgaaaaa caagatcgcc gtcaatgtaa aaggggagtt gaaacgaact tcagcactca
     9061 ttggtaaaac aggaacattg atgaaagaaa tcgaaaatga agtacaacac atattgggaa
     9121 caaaagagcc agtgaaagta tcggtgaaat acacaggctt tgaagaacca gctaaacgaa
     9181 gcaatgaccg caaacgagta gaataggggg gaccaaaaat gaaagaacta ttttcgacat
     9241 acaagctccc tatcatcttt ggggtacttg gattgatatt agccgtttta tggatcaccg
     9301 tgggcttttt caagacctta ttgatcttga tcatggcagc gatcggcgtc gctatcggtt
     9361 tttatctgaa acaaacgaaa atcttagatc actattttaa atcttaggag gaaacatcca
     9421 tgaataacaa taacaaaaat aataacaata aaatgaacaa ccaaaaacca gtgtctgcac
     9481 atccagaccc aacgacacca aaccaatcaa atggtgtgaa cgatgaaaag aacaaaacag
     9541 caccagtatc tgcacatcca gatccagtag tccctaacgt tcaacaagga gtagaagaga
     9601 agaaacatga tgcagaaaag catgcacctc atcatccagg aactccagaa tctaaagttc
     9661 cagaacaaca tgatgcaatc gatccttcta aacctgtgga agagcaaaaa catccttctg
     9721 accatgcgaa agcacaagaa aaacttagtt ctgaccacac aaacggacaa ggaaaacttg
     9781 gttctgatca tacaaataac caaggaaagc atgattctga acaggaagat tcaatgcgcg
     9841 gtgagctgaa ttatgaagat aaagttgtgc aaaaaatcat cggaatcgca attgaacaag
     9901 tagacggttt attatctgca aacggtggtt tcttctctaa tgtggcagga aaacttgtga
     9961 atacagataa tgtaacggct gggatcgaaa cagaagtcgg taaaaaacaa gtagcagttg
    10021 atatggatgt cattgtggaa tatggcaaag atatcgaaaa aatctttgaa gaaatgcaag
    10081 aagtaatcgg caaagaagta aaaaatatga cacatttaga agtgatcgaa gtcaacgcta
    10141 acgtagtgga catcaaaaca aaagaagaat ttgaaaaaga tcaagaaacg gtgcaagaca
    10201 aagtaactga cgcagcgaaa aaaaccggtg aatttgcttc gaatcaaaca gataaagtaa
    10261 aatcagcagc tggaagcggc gcacaaaaag taaaagaaaa tacagaacca cgggttcagt
    10321 aataaggaag taaaacatta ggaggaacga aacatgggat ttatttggtc acttatcgtc
    10381 ggaggaatta tcggagcaat tgcaggagca atcacgaata aaggttcttc gatggggatt
    10441 attgcaaatg tcgtagcagg tttagttgga tcagcacttg gtcaagcatt attaggttct
    10501 tggggaccaa gtattgcagg aatggcaatc gtgccatcat tgattggtgc catcatttta
    10561 gtactaatcg tatcattctt tgctcgaaaa ctgtaaaaag acttttaaaa agaggtcgtg
    10621 aaaaagctgt tcttcatcaa gtaataagaa cagccaaaca aaaatagctt ctcatatttt
    10681 tcatttggtt gggcatatta tcgaagatgc aagcttttga acactgttta tacggaataa
    10741 gaggctgtga caagactttt gtcacagcct cttatttatg cgggcaaatt cccaattaga
    10801 tttttaaaag tttttcctta aatgtgtctt tattgataca gagaagcttc tttaataaaa
    10861 caatgcctcc ctaaattttc ttgagatagg aaaggtgaac atacaaaata atacgaccac
    10921 tttgaaaacc cagatgatcc acaaatggat cgtatgatac tgatgaagta aaaagcaatg
    10981 gatcagaaac tcaaagagat tgaaaaagac aaggaagaaa taatatctct tttttactct
    11041 tgtctgtttt agccaataat agctcgtaaa gtaatctaga caaacaaata gaagtaaaca
    11101 aagtttcgta agagcagcaa tcgtatcatg ttgctctgct agacgattga cgagcaggaa
    11161 aaatgttggt aatggaatat agatcacgag taatgaaaga aaaaagtaaa caataaatgg
    11221 catactattc ctcctaattg tgtgagttcg ccctcatttt aaaataacga tatttgtttg
    11281 tgaagctttt tcgtgtcgta acaaatgtta tctaatgtat ttttaaataa ataatcatta
    11341 ttatcaaaat aatgtcagac tgtagacaaa gtccattt
//
LOCUS       DACDLM010000085        10936 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.087, whole genome shotgun sequence.
ACCESSION   DACDLM010000085 DACDLM010000000
VERSION     DACDLM010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10936
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.087"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..154
                     /locus_tag="IV356_002437"
     CDS             <1..154
                     /locus_tag="IV356_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAP9016086.1"
                     /translation="SLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTL
                     RYSLGY"
     gene            complement(235..1218)
                     /locus_tag="IV356_002438"
                     /pseudo
     CDS             complement(235..1218)
                     /locus_tag="IV356_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311512.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
     gene            complement(1613..2455)
                     /locus_tag="IV356_002439"
     CDS             complement(1613..2455)
                     /locus_tag="IV356_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAP9016087.1"
                     /translation="MKGDVIVEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAG
                     ANKKLVYNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLK
                     ILTTFLYVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKF
                     VYDDFSDELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIGI
                     PYINNLGLPEQEVMKIGNKLNDSRVEKILTCHCTGSKAFNILKTQLGNKLEAIKTGQH
                     LEIS"
     gene            2780..3196
                     /locus_tag="IV356_002440"
     CDS             2780..3196
                     /locus_tag="IV356_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAP9016088.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            3193..3663
                     /locus_tag="IV356_002441"
     CDS             3193..3663
                     /locus_tag="IV356_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP9016089.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            3677..4450
                     /locus_tag="IV356_002442"
     CDS             3677..4450
                     /locus_tag="IV356_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP9016090.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAASPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            4464..5276
                     /locus_tag="IV356_002443"
     CDS             4464..5276
                     /locus_tag="IV356_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP9016091.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            5330..6295
                     /locus_tag="IV356_002444"
     CDS             5330..6295
                     /locus_tag="IV356_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP9016092.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            6432..9155
                     /locus_tag="IV356_002445"
     CDS             6432..9155
                     /locus_tag="IV356_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP9016093.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESQILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGGSIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            9168..9800
                     /locus_tag="IV356_002446"
     CDS             9168..9800
                     /locus_tag="IV356_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP9016094.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKALRKEVKPLLDFLKKRDIP
                     LALASSSPAVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTAALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            10005..10232
                     /locus_tag="IV356_002447"
     CDS             10005..10232
                     /locus_tag="IV356_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009320234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HAP9016095.1"
                     /translation="MLQQNQNTNSYQAAILTAVNLGGDTDTTAAVTGALAGILYGGEV
                     IPENWRKSLQNDQLLKTISQRFCDTVLSQRI"
     gene            10301..10567
                     /locus_tag="IV356_002448"
     CDS             10301..10567
                     /locus_tag="IV356_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAP9016096.1"
                     /translation="MLVQMMNGGRIMSQSTITFRIPDDEKELVLEYAKAHNSSLTELY
                     RNAVLDKIEDEIDLRTLRSAIEVSKEKKESGISQEEMEKLLNEL"
     gene            10557..10826
                     /locus_tag="IV356_002449"
     CDS             10557..10826
                     /locus_tag="IV356_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAP9016097.1"
                     /translation="MNYKVIYMPQAQKQLKKMDRNQAKIIVAWIRKNLENTTDPRQHG
                     KGLTGNKSGEWRYRIGNYRILANICDSEIEIQIFSIGHRSTIYKR"
BASE COUNT         3625 a         1742 c         2137 g         3432 t
ORIGIN      
        1 ttccttagaa aaattaggtt gtcaaaattt caactcacgt tctgttaaag ggctagagag
       61 tagatttgaa agcatattac tggcttacag tgttctatta agtcgagcac aacgacgttt
      121 tgaaggaact ttgagatatt ctttaggata ttaaaattaa ctagcaccac gggtaaaata
      181 aatagttttt ctatcaagta tattgaacta cgataaattt gttattttgt tttgtttaat
      241 ttcgttgtac ttattggctt tgacttcgat ttctttaaat actgggtaat cggtgtccgg
      301 caaagctagc aaatctgttt tttctgtgtt ccatagatca ttgataatga catgtttttc
      361 gtaatggatt cgctctcgat cgtgtgacag ctccaccgct aatgcctcgt tgaaactggc
      421 gaaatccttc ataatcggtg tagatgaaaa gaagttgtac cgtacatagc cgactttgtt
      481 ttccatacta cctttctcgt ttccgctacg tggattgcac acctgtgtct caaaaccata
      541 gtgcatagaa aatcggagga aaccgtcagt cagcaccgct tgttcagtct ttgtttttgt
      601 ctaagtaacg gccgttgaca tattatcaat ccgtattttc cgaggaacgc cacctgattg
      661 gctgaagagt tctttcatgc cttccaacaa acattcttga ttctcggcgg ggagtacaac
      721 ggcgaatcct gcattactaa aagggaaagt catcactaat accttcacat ctttaaacgc
      781 tccatcgtga caaacttcca tcgtaccaaa atcaagttgc gcttctgctg gcgggtgttc
      841 aagacgctca aagccttggt cttccagtgt ttccaagtag tgtgtcgctt tccaatcttg
      901 aatgaataca cagactgttc ggtaggatcc tggaaagcca tcggctttta aagcagtagt
      961 cattgcttca gcagtcctac gctttttatt tggcagctta gcatcttctg aaagccatag
     1021 ggaaacgatg cctccccact tttctgtata catcatacca gtctttttgc gtgctttagg
     1081 ttgcggcagc aaatcatcat ctgcatattt tttagccgtg cgccaattta catctagctc
     1141 ctttgcaata tgattaatgg atttatcatg attatttcgt aaatttctga tagtattaat
     1201 atcggtcatt gtgagcatac ctttcttacc tccagttaca gtgtcgagac tataacttta
     1261 gaggagtttc aggttgcccg caatggcttt ttatcttaac ttaatcgatt tgcggagttg
     1321 tgtagttttt cgttgcactt gtatgtactt ttattctgcc ataaacagct taatgaatgt
     1381 ccacttgaaa aagtgaataa acgaaataga tgactcgatt taataaggaa gtaaacccac
     1441 acagaaatat aggtgatttt ccttgaatga ccaagatatt gaaagttagt gaaaaaacac
     1501 aaaaaggtag ccctattcac agaaggtctg ccttttgtgt tatcgccagc aaacattaga
     1561 gggggtattt catatagctt ttgtcctctc gacagtccta tcagtttctc ttttaactta
     1621 tctctaagtg ctgtccagtt ttaatagctt ctagcttgtt tcctaactgt gtttttaata
     1681 tgttgaaggc ttttgaacct gtgcagtggc aagtaaggat tttttctact cgtgagtcat
     1741 tcaatttatt tccaattttc attacctctt gctcaggtag acctaaatta tttatataag
     1801 gtatgccaat catatggaag ccaccaatta ggtattttat gggtttagtc ggaaatgttt
     1861 caagagcaat ttccatcata tcgataatgc catgatgact acagccagta aagacaatca
     1921 gaccgtcttc ttgctcaatt acgaccaata attcatctga aaaatcatca taaacaaatt
     1981 tatcatccat ctttttgtat aaattcttgg tggtcgagtt tgctttgcct agggggatga
     2041 tatggaagct cggagcaagt tctgttttcg tttttattgt atgtaaattc tcatgcattt
     2101 taaggatttc atttttagga ataccaacat acagaaacgt ggttaaaatc tttaaataat
     2161 ggggtaaagt tacaccttca gctgtataaa taggggcgtt tcctgatttt aaatatctta
     2221 acccgccggt gtggtcagaa tgaccgtgtg aaataatcac tgcctccaga tcattcaaag
     2281 tttcccccat tttagtcgca ttatagacta attttttatt agcgccagca tcgaagagat
     2341 atttcttccc tgagtagtta attaagagag ataacccatg tccactttta aagttcaaat
     2401 ttattcttga gttttcaaat aaaaccttga tttccactat aacatctcct ttcacatgaa
     2461 cgtgtattca tatattgtag cacattaagt tctatttttt gttgtaatta ccgaaaaaaa
     2521 tattaatgga cgctttttac gctttatttc gtatgtggaa gaaaatttct taggatgtgg
     2581 cgggggattg gggcaaagct aaattccaat tacagtgatc atttaattag acacctttaa
     2641 atacccacac tttcatcaac actataattt agggaaagaa aagtgttggc atgatataga
     2701 aaaaccttta attaacagcg tttcctaaaa ttggcacgca tcttgcttat agaaaagcgt
     2761 aaggatagga ggaatgaaaa tggcaactat aattcttgcc agccatgggg aatttgctca
     2821 aggattaaag caaacagcga caatgattat tggagatagt gtaccaattc atgccttgtc
     2881 agcatttaga gatgaagatg aatctatttt ggtacaaata aaaaaacttt tagccacaat
     2941 agatatagaa gaaacctaca ttttaactga tattctaggt ggtagtgtga ataatgatat
     3001 gctcactatt attaaagagt atgagggatt gcaattaatt actggaatga acttaccttt
     3061 agttatttct attgcaacct ataatggaaa aattggggaa agtgagctag aaaagcttat
     3121 taaagagagt caacaatcag tgattgattg tagaaaatta ttagtagaac aacttactgg
     3181 aggagatgac ctatgattaa gttagtacgt attgaccatc gtttgttgca cggacaggta
     3241 gtattttctt ggagtaaatc attaaatatc aatcgtatta ttattgccaa taaagaggca
     3301 gcgaatgatg aattcaaaaa aatgtctttg aatttatcta aaccgactgg cattaaatta
     3361 acaatttttt cagttgaaca gttactagaa aaaatgccta aaatcgaaac acttaacgaa
     3421 aatatcatgc ttatttttgg taatacaaaa gaaattcgtc aattttgtga agcctatcct
     3481 aaagtacaag aaatcaacta tggagggata atcaaaaaag aaggttccaa gcaatttagt
     3541 aatgccattt tcttgaatga atctgagcaa gaagatgcca aaaaattaaa agctcttggc
     3601 attaaacaat ttattcaaca ggtaccaact tctaaaaaag aagatttgaa tacaatgtta
     3661 taaaggagga atgaaaatgc tcgttcagtc aattggttta gggttaatcg gtgttttttg
     3721 tattttagac tcaaggcttt taggaagaat gaattttgaa cgaccgttga ttgtcagtac
     3781 gcttgttggt ttggtacttg gagacatgga aaaaggatta attgttggag cctctttgga
     3841 attgatgtcc ttaggattag taaatatcgg agctgcttca ccacctgata tgaatatggc
     3901 atcaattatt gctacagcct ttgccatttt atcaaatgcg aatgcagaag cagcattaac
     3961 gattgccatt ccaatttcag tgttaggtca aatactaggt atcttaatgc ggacgatttt
     4021 gtcaaatttg actcacgttg cggatcgctt tatcgaacaa ggaaaattta gccaagcaag
     4081 gagaattcat atactttatg gctcgggatt atatgctctc atgtatttta ttcctatttt
     4141 tctagcaatt tattttggaa cgaatcttgt ttctcagatt gttgatgcga ttcctgagtg
     4201 gctaacaaat ggcttaacgg ttgcaagtaa aattttacca gcatatgggt ttgcgttgtt
     4261 attacaaacg atgttaacga aaaaaatggt gccattttta ttacttggat ttttaattac
     4321 tgcttattct ggattgggaa tcattggtat tgcagccttc gcatgtattg ttgcgtttgt
     4381 catggttcaa gttcaaggta aaaactcaaa tggtaaccaa aatgagccag atccattaga
     4441 tgacttataa ggaggtagat taagtgaaag agaaagatca aaatgcatgg aaatatcggc
     4501 agttcttatg gcgttcatgg gcaattcaag cctcatggaa ctatgaacga caaatgaaca
     4561 tgggttttat gtacggaatt gcaccaattc tagataacat ttacaagaat ccagaagatg
     4621 aagcaatgaa gaaagaagct tacgagcggc atatgatgta ctacaactgt acccctcaaa
     4681 caagtgcatt tgtgttaggg ttaactgctt ctatggagga gcaatactac gaagaccaag
     4741 aaaactttaa tccggaatca atcagtgcag tgaagacttc tctgatggga ccgctatctg
     4801 gtgttggtga ttctttcttt caaggaacga ttcgggtatt agcctttgga ctaggaatta
     4861 atttagccca acaaggtagt attttaggtc caattctagc aatgttaatt tcctttgtac
     4921 cttccttttt agttacttac tatggtggga aaattggcta taacatgggg aataaatact
     4981 tgtctaaact gtatcaagaa ggtttgatgg ataaagtaat gtatgtttgc tccattgtgg
     5041 ggttgatggt cattggttcg atgattgcca gcatgatcgg gattacaaca ccaattcaaa
     5101 tgggtaaagc ttttgtctta caagatgtat tagatagtat tatgccacaa tttttaccat
     5161 taggattaac cttcttcatg tactggttat tgcagaaaaa ggtcaaaaca ggatggatgt
     5221 tggcaatctg tttagtcgga ggaattattt ttagtttgtt aggtatctta caataaggga
     5281 ataaccaata aatttggttg aataatataa ataaggagga attcaattga tgaattcaaa
     5341 agaaattgtt aaagaaatcg tagcgaaaaa agaggtaaaa tcaatcgtat ttgttggctg
     5401 tggcgcttca aaagcggacc tttatcctgc aaagtatttt ctagaccaaa atgcgaagca
     5461 gttacggatt agtcattaca cagccagcga atttaactat gcaacaccag catctgtaga
     5521 tgagtcaact gtcgttattt cagcttcttt aggaggtacg actccagaaa cagttgaagc
     5581 taacgcagta gctaaagaaa aaggtgctac agttattagt ctaacacgaa gcattgactc
     5641 accgttaaca aaagatgcag attatgtaat ttatcatcga tttgcagaga actatgctgc
     5701 taaattagaa aaaacaggct actgtttaga attggcagta gaacttttac atcaagtaga
     5761 aggttatgac cattatgaag caatgcaaga aggatttgct actatctatg atcttgccca
     5821 aaaaagtgca gaatcagctc gtaaagatgc gaagaaattt gctgaacgct ttaaagatga
     5881 aaaagttatt tatgtaatga gtagtggtgc tacacatgaa gtagcatact caacatcaat
     5941 ttgcttgatg atggaaatgc aatggattaa ttctggtacc ttccattcag gagaattttt
     6001 ccacggacca ttcgaaattg tggataaaga cgtaccgttt atattattaa tgaatgatgg
     6061 aaaaactaga aatatagatg ctcgagcatt aactttcctt gaacgctttg atacgaaaac
     6121 agaagttgta gatgccttgg attatggctt gtcttcacat attgctaaag aagtcttaga
     6181 ctactttaac ccattcgtga ttactgcagt atttagagtt tatgcagaag aattgtcaga
     6241 agcaagagaa catccattaa ctaagagacg ttatatgtgg aaactaactt attaaaaaat
     6301 agatcaaact aaataaggtg gcttgagaaa ttaagccacc ttgttttctt caatgtgatt
     6361 ttatacatat ggtaaaataa ctagtacata tggtaaaata actagtacat attgtgaaag
     6421 caggtggcaa gatgcagcga ttaaatgact atctttatca actaacattg cttttgaaat
     6481 ctacgccttc agataattat tcagctcgca gtatttcgca agctctacag ttgaatagaa
     6541 gtacaatcag tagctactta aatgaaggtg ttcgtgaagg gcttttcata aaagtaaaaa
     6601 gttacccggt tttattttta catagaacag ctcttgaaga actacatatc acactgaata
     6661 actccgaaat agaatcaatt gaaagcttgt taacaatttc tcaaaaaccc gcattagatc
     6721 aagtaattgg ctctaaagga agtttgaaag aagcaattga tcaaattaaa acggcagtct
     6781 tatatcctgg aaaagggttg cctttattat tgatcggcgc tagtggatca gggaaaacct
     6841 ttctagcgaa taaaatatat gaatatgcag tagaagaaaa ggtcattcac acatcggcac
     6901 ctttcataga ttataattgt gcacaatatg tgagcaatcc agagttacta tcctctgctt
     6961 tatttggcta cacgaaagga gcatttaccg gagcaagcca ggagcatact ggtttgctag
     7021 aaaaagccga tggaggagta ttgtttttag atgaagtgca tcgcttatct gaagaagggc
     7081 aagagaaatt atttacattt atggatacgg gtgaattctc tcctatgggg gataatagta
     7141 ttcggaaaaa agccgatgtt cgattagtct ttgcaacaac agaaaatata tatacgactt
     7201 tcttaccaac ttttcttagg agattgccag ttattgttaa tctacctaga tttcaacaac
     7261 gtccgtcgtt tgaacgtctg tcattgattg atgaattttt tgtttctgag agccaaattt
     7321 tagctaagga actatctgtt tctgatgcat tgattcattt cttaatgaat agtgattttg
     7381 aaggtaacgt ggggaatatt aaaaatatta tcaagtatgc ttgcggaaac gcatatatcc
     7441 accagaagag tcagcaaaca attcaagtta aattattgga tatgccttta gagtacagtt
     7501 ataaattcaa ggagcaacta aataaaccca gaaagaaaag agcagatcga atctactatc
     7561 cagaagaaac acgacaagtg caactagaaa gaaacaatca gctttttgtt caattttttg
     7621 accaattact tactggattc tctgaagtga ttgaaaataa caaggatatt aaactatttt
     7681 tagaagaaat ggttaccaag gtaacacaag taatggatac gcttattttt caagaggatt
     7741 acgaaaaaga gcagtcttta tacgccattc taaactatca tattcgtcaa agtattgatt
     7801 ttatgcgaga aagctacggg tttgaacaag atggtaaccg ggtagtcgct ttggccaact
     7861 atctatatgt caaggataat caagtgattt ttgaaaatag tcttcaagaa aagaaaacca
     7921 aagatcagct taacgaattt tttgctaatg ttcttgaaac cccttattgg tatgcaaaaa
     7981 aaatcttaag ccttttatct gagtgtttag atcaacctgt gtatgaagag gacattttct
     8041 ttattacgct atatttttat agtttgaatg tcacgaatgt taaaacaggt attaagagta
     8101 ttgtgctagc tcatggttat tctacagcta gtagtatggc gaatgttgcc aaccgtatgc
     8161 tgaataagaa cgtttttcaa gcttatgata tgcctttaga tattacatta gagaaaattg
     8221 aagcaaaatt gattcaattc cttggagatt atcgaacaga ttcaggcttg attttattgg
     8281 tagatatggg ttcactaaac caactaggcg gtttattagt gaatcatcta aatggaccac
     8341 tgttaatcat tgatcatatc aatacaccgt tattattgga agtcggccaa caagtattaa
     8401 acaataaaag tatcaccgaa ataggagcag aaattgaaac aagtcttact ttcaaaaagc
     8461 agttactact tcccaagaaa aagaaaaaga aagccatcat tacttgttgt tatacaggga
     8521 ttggtagtgc gacccagatt caggagattt taacgaaatg cttgaaagat gcagttagag
     8581 aattagtaat tattccgtat gattacaaaa agctgttaga aaacaagaat tttgagactc
     8641 cttttcaatt atacgatgtc atcatgattg taggtacaga agatcccaaa attaatcaga
     8701 ttccatatat tggattagat cgcctgatta atgggggaag cattggcgaa tttgttcatt
     8761 acttggaaaa agagctgact attgaagtga acgatttaca aaaagaatta attttcaatt
     8821 tttcaattag taaaattgtc gaaaatttaa ccattttgga tccagataag gtgctatctt
     8881 ttgtacaaaa agcaattaaa gaattatcga agttattaaa ttttgatttt tctaataatc
     8941 agctgttttt gttgtacctt cactgtagtt gtatgattga acgaattgta cgtaaagaaa
     9001 gtgtggatga gcaagaggac attgaagaat atatgcaagc aaatggagaa ataatggata
     9061 aaattcatag cgcttttttt gagattgaaa gggaatacac aattgaaata ccagatttag
     9121 agttgcgatt attgagcgat attgttcaag gataggagtg aattcgaatg acaatgggag
     9181 taatttttga tatggatggg gtactcatag atagcgagac attttatttt gagagaagaa
     9241 tgaacttctt tcaagaactg gagatagatc caggatcaaa ccagattgat gattatgtgg
     9301 ggaaaacaga agctgcaata tgggaaacat tagttcctga ggacaaatca ttaagagagg
     9361 aactttatcc gaaatatgta gattatcgaa aaacgcatcc aattgatttc gctaaagctt
     9421 tacgaaaaga agtgaaaccg ttacttgact tcctcaagaa gcgggatata ccattggcac
     9481 tggcatcttc ttctccagct gtcgagatag agagtatgct cattcaatgt gaacttactg
     9541 aatatttttc ctttgttata agtggtgagt cattaaaaca aagcaaacca catcccgaaa
     9601 tatatttaaa agcgaaacag caattagact gtgacttctt tattgcagta gaggattcaa
     9661 cgattggtat taaatcagca aaggcagcaa atatctatac ggcggcacta aaacaaccaa
     9721 tgcaaatcga tcagagtgaa gcagacatac aaattgaaag tctacaagaa ctggaacaaa
     9781 ttgttttaga aaaaggttag tgaattaatg gaaataaggc tatatatctg tgctagctat
     9841 tttgactaac caaaaaaact tgctataatt caggtgtagt aaaaggtgct ggtaacacct
     9901 tttacgaaaa tgcttcggca gtgataatgg gattggcttt ttaagttttt tattttgttc
     9961 gcaatcccta aggtcatgtg aatgatccta gggattgcta gaatattttg caacagaacc
    10021 aaaatacgaa tagttatcaa gcagccatat tgactgcggt caatttagga ggggatactg
    10081 atactactgc tgccgtaact ggtgctcttg cgggtattct ttacgggggt gaagtgatcc
    10141 ctgaaaattg gagaaaatcg cttcaaaatg accagcttct taaaacgatc agtcagagat
    10201 tttgcgatac cgtgctatct caaagaattt gaataatgga tatgatgcaa atcttgtttg
    10261 tactaacgtt gtattgacaa aaaggatttt atttagtaca atgttagtac aaatgatgaa
    10321 cggaggtaga atcatgtctc aatcaaccat tacatttagg attcccgacg atgaaaaaga
    10381 actggtatta gaatatgcaa aagcacacaa ttcttcattg accgaacttt atcgaaatgc
    10441 tgtactggat aaaatcgaag atgaaatcga tctacggact ttacggagtg caattgaagt
    10501 ttccaaagag aaaaaagaga gtggtatttc tcaagaggaa atggagaaac tgctaaatga
    10561 attataaagt catctacatg ccgcaagccc agaagcaatt aaaaaaaatg gacagaaacc
    10621 aagctaaaat aattgtcgcc tggatcagaa agaatttaga aaacacgact gacccgcgtc
    10681 agcacggaaa aggtttgact ggaaataaga gtggggaatg gcgctatcga attggaaact
    10741 atcgaatatt ggctaatatt tgtgattctg aaattgaaat ccagatattc tcaattggac
    10801 atagaagtac aatatataaa agataaccgt ttttggaacg aagtagagtt tcgaaagtca
    10861 atgtataatc ttttgaattt tgcataatac cacaggtaga aactacccga tactatcggt
    10921 tggtttctgc tttttt
//
LOCUS       DACDLM010000086        10595 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.088, whole genome shotgun sequence.
ACCESSION   DACDLM010000086 DACDLM010000000
VERSION     DACDLM010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10595
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.088"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..523
                     /locus_tag="IV356_002450"
     CDS             <1..523
                     /locus_tag="IV356_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016098.1"
                     /translation="EKAIPYIAAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTIS
                     NEINQYREREPEIQPAEVKQEHKNTVETAEQKNIVPVGSLWIDKKDGKVMEEDTGRTL
                     HLKDAAFIEDPQHNQVILKGKSYGKEIQTALPSEEFALGNSFRFSLETVSEVAKRKNE
                     IYYEQQLSQKERV"
     gene            584..2044
                     /locus_tag="IV356_002451"
     CDS             584..2044
                     /locus_tag="IV356_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HAP9016099.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFIPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            2055..4259
                     /gene="topB"
                     /locus_tag="IV356_002452"
     CDS             2055..4259
                     /gene="topB"
                     /locus_tag="IV356_002452"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP9016100.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAESIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ENDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            4498..5091
                     /locus_tag="IV356_002453"
     CDS             4498..5091
                     /locus_tag="IV356_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP9016101.1"
                     /translation="MKDKIQCIFDKHNGNLSLKDARSEGLSPMTLDRLAEKDKIEKVA
                     PGFYTLKDAFVDELYLAQSIYSRGIFSHETALDLFQVGTYIPKKINMMFPKGYNVSKE
                     KLDQYAIQPHYTNKENFDLGVTETESFYGNKILVYDLERTLCDMWNPRYKASVEVKQE
                     ALKEYMTSTSRNTNKLRRYMDILKSPKEMTLYMLPLY"
     gene            5107..6006
                     /locus_tag="IV356_002454"
     CDS             5107..6006
                     /locus_tag="IV356_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HAP9016102.1"
                     /translation="MTPTQFKEKTRNFAAEKHLNPQIVQRYYMMEKLLECIVESPYHD
                     DFVLKGGFLIGSKYGLENRSTVDIDTTYRNSKLTKEKLETVFSELTANPTKDGIRFEL
                     KGLTETREADYYPGFQAKFIAYLENARVPFKLDITSGDSIIPAALMYEHKLMFEDKTI
                     HIPAYPTEQILAEKLHATFSFGKDNSRMKDFYDLYMIPKLERIDEKNLYKSVQGTFKE
                     RNNQSVFKHLYDQEMPQLVKDEGLREKWKRYQQENYFAKDISFESTLTSVDSLMQSIV
                     EQEKAERKQNFKRSQQMNQEMER"
     gene            6009..6494
                     /gene="ssb"
                     /locus_tag="IV356_002455"
     CDS             6009..6494
                     /gene="ssb"
                     /locus_tag="IV356_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAP9016103.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFSLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRMHADQSSSSPSPTTFEQRDTATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            6860..7120
                     /locus_tag="IV356_002456"
     CDS             6860..7120
                     /locus_tag="IV356_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016104.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            7568..7774
                     /locus_tag="IV356_002457"
     CDS             7568..7774
                     /locus_tag="IV356_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HAP9016105.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPYTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            7774..8025
                     /locus_tag="IV356_002458"
     CDS             7774..8025
                     /locus_tag="IV356_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016106.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYENEYWLTKLEN"
     gene            8041..8478
                     /locus_tag="IV356_002459"
     CDS             8041..8478
                     /locus_tag="IV356_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016107.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGQWFFQALLCLEAGVKPNTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYLENVNKYGACYIMKKEDNENE"
     gene            8471..9166
                     /locus_tag="IV356_002460"
     CDS             8471..9166
                     /locus_tag="IV356_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016108.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKRRPDTLKKGAELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEELNSKDATVDDYYLVFTKFLTCGTE
                     SIVLMGMDYELAVPEVFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNELDRK
                     RMPYQRFERKKGQ"
     gene            9547..9726
                     /locus_tag="IV356_002461"
                     /pseudo
     CDS             9547..9726
                     /locus_tag="IV356_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            9788..9972
                     /locus_tag="IV356_002462"
                     /pseudo
     CDS             9788..9972
                     /locus_tag="IV356_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003027804.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module toxin, HicA family"
     gene            10006..10437
                     /locus_tag="IV356_002463"
     CDS             10006..10437
                     /locus_tag="IV356_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HicB family protein"
                     /protein_id="HAP9016109.1"
                     /translation="MLSEPLAKTYPAIFSPEEGGGYFIEFPDVQGAYTGINEDDISYG
                     IAMAQEVLGMVLADYIEHEDLLPEPTPINKISVEDDSFTTLIRVDVAKYLKDTELVKK
                     TLTIPQWADKLGKRAGINFSVLLTESIADKADNILRSGRNN"
BASE COUNT         3865 a         1782 c         2194 g         2754 t
ORIGIN      
        1 ggagaaagct attccttata ttgcagcatg gacgaagaat ggtcagacgt tggatgataa
       61 ggaagctgcg gaacgtggga aaatcatgaa tgatgtcagc cgtgtcgcaa atgaattcat
      121 tcaaaccatt tctaatgaaa tcaatcaata cagagaaaga gaaccagaga tccaaccagc
      181 agaagtgaag caggagcata aaaatactgt agaaacggca gaacaaaaga atattgttcc
      241 tgttggttca ctttggatcg acaagaaaga cgggaaagta atggaagaag atacgggtcg
      301 aacgttacat ttgaaggatg cggcgtttat tgaagatcca cagcataatc aagtaatttt
      361 aaaaggaaaa agttatggaa aagagatcca aacggcgtta ccttcagaag aatttgcgct
      421 aggaaattca ttccgatttt cacttgagac agtgtcagaa gtggcaaaac gaaaaaatga
      481 aatctattat gaacaacaat tgtcacaaaa agaacgtgta taaaacaagt aaaaaagact
      541 atctgaaaaa cggatagtct tttttctttt gggaggtttt aaaatgaccg agaaaaaaat
      601 gagtcttatt gatcgatgta aacagatcga tatagtggat tttgctcgaa acaatggaat
      661 ggctgtagtc aataaaggac gagactatcg cttagaagac catgattcat ttgtttttga
      721 tcgaagaaaa caacgttttt attggaacag tcaaaatatt agtggcgaca ttattgaatt
      781 agctaaactt tttttcatag acaaagagat ccaagaccct aagcaacaat ttaaagcagc
      841 cactgatttt attctaaaga atgaagacaa aacagaacga gtggaaaatc ttcattttga
      901 gacagaaaag tacaaagatc accccgttga ttatcaacca ctcacagaaa aaggaaggaa
      961 ttatctgaag gaagaacgaa aactaccaga gtggctgatt gattatgcag aaaaagaagg
     1021 gttgattgcc gaactaaagc caaaatatga acggcaaaat ttcttagttc gagacgatcg
     1081 tttagatcat gcggtcgcct ttttatggaa agatccacag acaaaagaga cagtaggggc
     1141 gagttatcaa ggaacgttca ttgattatga acgttttggt gagagaggca catataagca
     1201 tatagataaa aattcgacag cgaatcatgg ctttaaccta aagatcggtg accctaagca
     1261 gttaaaattt tttgagagta gtattgattt acttagctat gctgcactga atcgtgatca
     1321 gttaaacgat acgtggttag tctctatgga agggttaaaa caccatgtga tcagtcatta
     1381 ttttggtgag gcagtatctg aattgagaaa gaaacaagcc tttcctcaat ccatcgagat
     1441 ttgtgtggat aatgaccgtg caggacatat tttctacgaa aaagaacaat taatgggcgc
     1501 agtcgatcca tttacgaatc agaaagtacg ttgtgaacga ggaatcgcta atgattggca
     1561 agtgccaaaa gaatacaaaa tcatttatga agaagtcgca aaagaagaaa aggtcacacc
     1621 agaagctatt atggccatac acaagacaga aaacaatctg caattaacga accaactggt
     1681 ttccgctcac aaagtaaatg cgttttttgg ccagcagctt tctgttaacg attcaataga
     1741 agccattaat ttgaaagata tttgtagaga agtcgcaaaa gaattaaaag tttgtgaacg
     1801 cgtggatggt acgtacgatt ttgatcgttt ttatcaagaa aaaggggata ttaatgcgca
     1861 gattcttttc tcttataaag cagaacaata ctacaaaggc tataaaaatc atgaacatga
     1921 atttatacct gaagtaaaaa aggactggaa cgatcaattg aagcatgaga tccagcaaca
     1981 agaaatcaga aagcaaaaac gtgccatgtt gtttcaacaa ggcagacaac aagaaaggga
     2041 gtgaaatcgt catgatgaaa accgttattt tagcagaaaa gccgtcacaa gcgaaagctt
     2101 atgccgatag cttctctaaa gccactcgaa aagacgggta ttttgaaatc caagatcgat
     2161 tgtttcctgg tgaaactgtg atcacgtatg gttttggtca tttagtcgaa ttagattcgc
     2221 ccgatatgta cgatgaaaat tggaaacaat ggtcattaga acatttgcct attttcccta
     2281 cacattatca ctatcatgtt cctaaagata agaaaaagca attcaaggtg gtgaaacagc
     2341 aacttcaatc ggccgacacc attattattg cgacagatag cgatcgtgaa ggggaactga
     2401 tcgcttggac gatcattcaa caagtaggcg ccgatcaagg aaaaaccttt aaaagacttt
     2461 ggatcaactc cttagaaaaa gaagccattt atcagggatt ccagcagtta cgagacgcaa
     2521 aagagaccta tccaaaattt gaagaagcac aagcacgtca gatcgccgat tggttaattg
     2581 ggatgaacgg tagcccactg tatagtttac tcttgcagca aaaaggcata ccaggaagct
     2641 tttccttagg cagagtccaa accccaacgc tttacatgat ttatcaattg caggaaaaga
     2701 ttagaaattt caagaaagaa ccttattttg aaggaaaatc cgaagtaatc gctcaaaatg
     2761 gcgcatttga tgcgaagctt gatccgaatg aaacccaagc gacgcaagaa gcatttgaag
     2821 attatttaaa agaaaagggg gttcaattgg gaaaacagcc aggcatgatt cgccaagttg
     2881 aaaccgagaa aaaaagcgcg gcaagtccac gtcttttttc tctatccagc cttcagtcta
     2941 aaatgaatca gctcatgaaa gctagtgcca aagacacttt ggaagccatg caaggcttgt
     3001 atgaagggaa atatctaagc tatccacgaa cagacacccc ttatattacg gaaggggagt
     3061 atgcgtattt gttggatcat ttagatgaat acaagcattt tttaaaggcc gaatcaatcc
     3121 caacccctat tcatacgccg aatagtcggt atgtgaataa caagaaagtc caggaacatt
     3181 acgcgatcat tcctacaaaa acggttatga cagcagcggc ttttgaacaa ctaagtccac
     3241 tgcagcaggc catttatgaa caagtgttaa aaacaacggt ggccatgttt gcggaaaaat
     3301 atacctatga agaaacaacg atcttgacgc aagtccagca gcttcagtta aaggcaatcg
     3361 gaaaagtacc gatagatcta ggttggaaga agttatttgg caaagagaac gacggaaaag
     3421 agaaggaaga agagccgcta cttcctaaag tgacaaaagg agaaatggtg acggtagatc
     3481 tacaagtcct tgaaaaagaa accaagccac cacagcctta taccgaaggt acgttgatca
     3541 cggcgatgaa aacagctggg aaaaccgttg atagtgaaga agcgcaatcc atattgaaag
     3601 aagtggaagg aatcggtaca gaagcgacac gggcgaatat tattgaaacc ttgaaacaaa
     3661 aggaatatat caaggtagag aaaaataagc tcgtggtgac gaataaaggg attttgcttt
     3721 gccaagccgt ggaaaaagag ccgctgctta cgagtgccga aatgaccgcc aaatgggaaa
     3781 gctacttgtt aaagatcggt gaacgaaaag gaacacaaac cacttttcta gccaatatcc
     3841 aaaaatttgt ctctcactta ttggaagtcg taccagggca aatccaatcc actgattttg
     3901 gatcgacgtt acaagaagtg aaagcagcca gtgaaaagca agaagccgcg cgtcatttag
     3961 gaatttgtcc aaaatgccag gaacaagaag tcttactcta tcaaaaggtg gcagcatgta
     4021 cgtctgaagc ctgtgatttc aaactatgga caacgattgc caaaaagaaa cttacagcga
     4081 cacagctgaa agagatcatt caaaatagcc gaacaagcca accagtgaaa gggttaaaag
     4141 gtcagaaggg ttcgtttgaa gcaacgattg ttttaaaaga agacttcact acaggctttg
     4201 aattttctga aaagaaaaaa acgaacttca agaaaagaac acgacgcact acaaaataat
     4261 ggagggttaa tcttatgcgt aatacaacac acaaacaaca agaaatcgaa aatcaaaaag
     4321 ccaaaattcg ttcagaacag gaaaaaatgc gtgccagcaa acgaagactg cagcaattga
     4381 agaaccagca gcggattcaa aaagaaatcg aattagatcg ataaattcct ttcttgttaa
     4441 tataaaacta acatgttata gttgtgttag ttttatatta actttagggg aagagtaatg
     4501 aaagacaaaa tccaatgtat ttttgataaa cataatggca acctatcctt gaaggatgct
     4561 agaagtgaag gattatcgcc tatgacgtta gatcgattag ccgaaaagga taaaatagaa
     4621 aaggtagcac caggtttcta taccttaaag gatgcgttcg tggatgaatt gtatctcgct
     4681 cagagtatct attccagagg gattttttct catgagactg cgctcgatct ttttcaagta
     4741 ggaacatata tccctaaaaa gatcaatatg atgtttccta aaggatacaa tgtatcaaag
     4801 gagaaattag atcagtatgc cattcaaccg cattacacta ataaagaaaa ttttgacctg
     4861 ggagtcacag aaacagaaag cttttacggc aataaaattt tagtctatga tttagagcga
     4921 acgttatgtg acatgtggaa tccaagatac aaagcaagcg tagaggtaaa acaagaagca
     4981 ttaaaagaat atatgacaag taccagtaga aatacaaata agctaagaag atacatggat
     5041 attttaaaat caccaaaaga aatgactttg tatatgttgc cactttattg agaggagtaa
     5101 agatgaatga caccgacaca atttaaagag aaaacaagaa atttcgcagc agagaaacat
     5161 ttaaacccac aaattgtcca aagatattat atgatggaaa aattattaga atgtattgtt
     5221 gaatcgcctt atcatgatga ttttgtatta aaagggggat ttctgattgg atcaaaatac
     5281 gggttagaaa accgttcaac cgttgatatt gatacgactt atcgaaattc gaaactaaca
     5341 aaagaaaagt tagaaactgt tttttctgaa ttaacagcta atcctacaaa agatggaatt
     5401 cgttttgaat taaagggatt aacagagacg agggaagccg attattatcc aggttttcaa
     5461 gcaaagttta ttgcttatct tgaaaatgca cgtgtacctt ttaaattaga tattacttca
     5521 ggtgattcta ttattccagc agcattgatg tatgaacaca aattaatgtt tgaagataaa
     5581 acgattcata ttccagctta tcctacggaa caaattctag ctgaaaaatt acatgccacg
     5641 tttagttttg gaaaagataa ttcgcgcatg aaagattttt atgacctgta tatgattccg
     5701 aaattagaac gtatcgatga gaaaaatttg tataagagtg ttcaaggaac attcaaggaa
     5761 agaaataatc aatcggtgtt taagcatttg tatgatcagg aaatgcctca attggtgaaa
     5821 gatgagggct tgagagaaaa gtggaaaaga taccaacaag aaaactattt tgccaaagac
     5881 atttctttcg aatctacact aacttccgtt gattccctga tgcaatcaat tgtagagcaa
     5941 gagaaggcag aacgaaaaca aaattttaag agatcacaac aaatgaatca agaaatggag
     6001 agataaagat gatcaataat gtaactttag tagggcgatt aactaaagat ccagatttac
     6061 gttataccgc aagtggcaca gcagtggcga ctttttccct agccgttaat cgtaatttca
     6121 cgaatcaaaa cggcaatcga gaagctgatt ttatcaattg cgtgatttgg cgcaaaccag
     6181 cagaaacgat ggcgacatta gctaaaaaag gcagcttgat cggcgttgtc ggacgaattc
     6241 aaacacggac ttatgacaac cagcaaggac aacgtgtgta tgtgacagaa gttgtggccg
     6301 ataacttcca actattagaa agtaaagcag cgacagaaag ccgtatgcac gctgatcaat
     6361 cgtccagcag tccaagccct accacctttg aacaacggga tacagcgacg cctaacaaca
     6421 atggattgaa cgcttcacag aatccatttg gtggacaatc aatcgatatt agcgatgatg
     6481 atctaccgtt ctaagtagca ttttctattg gttgcatttg ctacggttta tgttataatt
     6541 tagacaacaa aaagaatttt caatctataa ccaaaaacca ctagctggcg ggctagtggc
     6601 tttcttttac gtttctatta taagaattaa cgggtaggct tactgtcttt cttggcaaat
     6661 ttacaatcaa gccatttgca gatatagtgc gcggctactt ctgccatgat tgcaaaaaca
     6721 aaatcaaaaa gaattttcaa acctataacc tcctcccctt gccagattag gccggggtag
     6781 cagacagcaa gactattata gcataattga aatatccaaa tgattggatt tttgctataa
     6841 ttttagcgag gtgattgtga tgaacaaata tgttggtttg cttgataaaa tccgagtaat
     6901 aaaaacgcaa ccgttattgg ttcgctttac tttacaaacg attcatgaat cgattaattg
     6961 tgtagttgca gatattgaaa ttatcgataa attgctaatt atggatgatg gaaaatacaa
     7021 tattgccgtc acaggtcact tcaataaacg aaatcagcta gttattgcta gcatgtatgt
     7081 tagaaatccc gatcatttta cgcgatcgat gggcatataa ataaaagaag agttgtagtc
     7141 ctaaatgagg attgcagctc tttttgtttt acatagaaac aagaaaaatg aaaaggcctt
     7201 tttaggaagg cgcaagcgcc ttctcaattg aaaaacctct ctctcactcc aaccgccacc
     7261 gccgttcgag aagaaaggaa gtgaacgttg cacgttcact aagataaggg gtcttgcaaa
     7321 gcaagacaaa atagaaaaaa cttcctctca ccaaaaggtt cgttcctgtt cgctatctct
     7381 ttattgattt gccagaccgg caacaagttg ccttttatca ccaaaaagcg acaaggacaa
     7441 gggtaaatgg cacgctgcac gcccttgtcc ttgtcgcttt tagttgattc attctggcca
     7501 acaaatcaat aaagaaagaa ctaacgaaag gaagtaaaac ctttcctaag aggaggcaga
     7561 atcaatcatg cgaaagaaat ttgattattg gggtgttccc ttcagcgaat tattcccaaa
     7621 ctatcatgca ccatatactg tcgaatgcga ttgtggagaa agagcgaaat gtatcaaaag
     7681 ctattgtttg tatcaatgtc caacatgcgg gaaaaaatat accttgtctt atggcgatta
     7741 tattttgatt gatgagaaag gaaagaaacg ctgatgaaaa cacaacacaa attattgact
     7801 gtaaaagaag tcgttcaaat tttggtggac aaagaagtca tttctgaaaa agtagcagaa
     7861 gctttactta ttccgcggta ctggacgata gaaacccctt tagtagagga tgcaccgact
     7921 atgctatttg aagacctagt gaagattgca ggatatgaac tgcattatca agaaaacatg
     7981 gaaacttatg aaaacgaata ttggttaacc aaattagaga actaaaaagg agaaaaaaat
     8041 atggctcaaa attactatga cgaatttgtc aaattacctt tggataaaat ggcacaaaaa
     8101 atggaggata tgacattcct atacaatgag acacgtgttc caaaaaaaca ttataaggaa
     8161 agattgtcgg tagctgtgga agaaatgatt gaatcgggtg tcgaaatgaa tctcattgcg
     8221 acctactatc gaacgcttga agaactgaaa aagcaaaatg gacaatggtt tttccaagcc
     8281 ttactatgct tggaagcagg cgtcaagcca aacactatca aaccttctga ataccaagct
     8341 ttagaactaa cgtatgggaa atttgtcgaa acgaaaaaag ccaagactgt ttcaagtgaa
     8401 tggttggact acttagaaaa tgtcaacaag tatggcgcat gttacatcat gaaaaaggag
     8461 gacaacgaaa atgaataagg tgatttatca actaacaacg gaagatgtgt cacacttttt
     8521 aacaaacaaa gaacatttga atgaagtaat cagacggatt caaaaagact ttagttgtat
     8581 ggaagaaatg aagtacttta ttcaaagagt cgaagaacaa ttgtatttgg aaagtgaaac
     8641 gagtcaaacg aaggttacag tcagcaataa ttatttagac gtgtataaac gtcgtcctga
     8701 cacattaaaa aaaggagcgg agcttctacg actagaaaca gaaaaatata tcatgaatgt
     8761 ttacctagaa aggagtgaac tggtcgaaaa ctttgtcagc tacacgattt gcaggaaaca
     8821 ctattactca gaatcagaat attattcaat ttttgagagc atggaattaa tggaagagct
     8881 aaacagcaaa gatgcgacgg tagacgatta ttaccttgta tttactaaat ttttgacgtg
     8941 tgggacggaa tctatcgtgt taatgggaat ggattatgaa ctcgctgtac ccgaagtatt
     9001 tttgagggaa tatgtagaag aagtagataa cccaggcgac gactggtaca cgactttaac
     9061 tgatttttta gatacctaca cttacgacga tacagaagaa atccaaaatg aacttgaccg
     9121 taaacgaatg ccatatcaac gatttgaaag gaaaaaaggt caataaccat ttataccgaa
     9181 aagtgagaat gtgtgaaata aaaacaaaaa accttgaaat taagggaatg gttcttattt
     9241 cgcaccaatc gctccaaccg cccccgccgc ttaggtggtg cgaaataagc gagcaaagcc
     9301 cgaaaaccta agagaaagaa ggagatttat atgaacaaaa ttattccctt attattagtc
     9361 ctatttgttg gagaaatact tatgcgactt agtgcagctg tacatttaaa cctcgcagta
     9421 tttttggtaa tactaatgtt ttgtttgatc ttttggcgat ttgtattagc cctcgtaagt
     9481 ctactattca agatgattgc agccatattt ttcataggat tatttcgatg aaaggagaga
     9541 gtaccaatgc caattgcaat aggaaataaa cggttacccg tgacgttgga tgaaaagaga
     9601 caaaaagaat tgcagtaacc aaagcagaag tacggcaaaa gtgaatccag gattatgtgt
     9661 attgcgttag atttattgat tgcgcaagaa aaagcaggat ttgacatacc agcactcaaa
     9721 aagtgatcgc actttgcgca cgtgttaata cgtgttataa ttattttgta aggaggtata
     9781 gtgcacaatg ccacttacgg gaaaagaaat gcttaagtta ttgaaaaaaa tggctgggtt
     9841 gagcgaaggc aagagggatt tcatcatcat ctttataagg atggtgttag aatcactgtt
     9901 cctgttcatg ccaatcaaga tcttggccga ggacttgagc gaaaaatttt aaaggatgcg
     9961 ggattgaaat aatctcgcat tcgattaaag aaaggattga ctgaaatgtt aagtgagcct
    10021 ttagcaaaaa cctatcctgc tatttttagc ccagaagaag gtggtgggta ctttattgaa
    10081 tttcctgatg ttcaaggtgc ttacacagga attaacgaag acgatatatc ttatggaatt
    10141 gctatggcac aagaggtgtt aggtatggtt ttagcagatt atattgagca tgaagatcta
    10201 cttccagaac caacaccaat caataagatt tctgttgaag atgattcttt tactacttta
    10261 attcgtgtag atgttgccaa atatttgaaa gacacagaac ttgtcaaaaa aaccttaaca
    10321 attcctcaat gggcggataa gctaggcaaa agggctggca taaatttttc agtccttcta
    10381 acagaatcaa ttgcagataa agcagataac attcttcgtt ctggaagaaa taattagaac
    10441 tcaaaagggt cagaaactta aaaatctttg gcttcttttt ttactacaaa gatggcttct
    10501 ttaaattatt tgcctgattg atttaaaaaa attgcgcaaa gactacgagc taattaagtt
    10561 gctcgtggtc tttttttatg aaaacttttt agatc
//
LOCUS       DACDLM010000087        10497 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.089, whole genome shotgun sequence.
ACCESSION   DACDLM010000087 DACDLM010000000
VERSION     DACDLM010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10497
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.089"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..361)
                     /locus_tag="IV356_002464"
     CDS             complement(<1..361)
                     /locus_tag="IV356_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HAP9016110.1"
                     /translation="MATVWMGLALVGNTFSPNSAMEGQGVIDVLTHIYTTGPAEYAKS
                     ILVNVFFGAFFGRVLVDSGIAATLIRKVVELGGDKPRITMSLLCIVTAVIFMSMTGIG
                     PVISIAVIVLPILMSLGI"
     gene            complement(713..1072)
                     /gene="rplT"
                     /locus_tag="IV356_002465"
     CDS             complement(713..1072)
                     /gene="rplT"
                     /locus_tag="IV356_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HAP9016111.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(1125..1325)
                     /gene="rpmI"
                     /locus_tag="IV356_002466"
     CDS             complement(1125..1325)
                     /gene="rpmI"
                     /locus_tag="IV356_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HAP9016112.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(1397..1921)
                     /gene="infC"
                     /locus_tag="IV356_002467"
     CDS             complement(1397..1921)
                     /gene="infC"
                     /locus_tag="IV356_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HAP9016113.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            2241..2873
                     /locus_tag="IV356_002468"
     CDS             2241..2873
                     /locus_tag="IV356_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAP9016114.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGNQSYLDAKN
                     MVLRESHIQKLTMQKTGLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTTIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(2875..3780)
                     /locus_tag="IV356_002469"
     CDS             complement(2875..3780)
                     /locus_tag="IV356_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAP9016115.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWEIALIISLVLSIWMLIALWRRIR"
     gene            complement(3865..4518)
                     /locus_tag="IV356_002470"
     CDS             complement(3865..4518)
                     /locus_tag="IV356_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAP9016116.1"
                     /translation="MIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFYAN
                     PEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEVCV
                     YDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYDYY
                     KELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVSI"
     gene            4840..5784
                     /gene="mvk"
                     /locus_tag="IV356_002471"
     CDS             4840..5784
                     /gene="mvk"
                     /locus_tag="IV356_002471"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HAP9016117.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            5777..6754
                     /gene="mvaD"
                     /locus_tag="IV356_002472"
     CDS             5777..6754
                     /gene="mvaD"
                     /locus_tag="IV356_002472"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HAP9016118.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKKGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            6767..7852
                     /locus_tag="IV356_002473"
     CDS             6767..7852
                     /locus_tag="IV356_002473"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HAP9016119.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            7849..8913
                     /locus_tag="IV356_002474"
     CDS             7849..8913
                     /locus_tag="IV356_002474"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HAP9016120.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKDPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAQEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(9162..9965)
                     /locus_tag="IV356_002475"
     CDS             complement(9162..9965)
                     /locus_tag="IV356_002475"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HAP9016121.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIRDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(9985..10290)
                     /gene="kduI"
                     /locus_tag="IV356_002476"
                     /pseudo
     CDS             complement(9985..10290)
                     /gene="kduI"
                     /locus_tag="IV356_002476"
                     /inference="COORDINATES: protein motif:HMM:NF002091.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
     gene            complement(10272..>10497)
                     /locus_tag="IV356_002477"
     CDS             complement(10272..>10497)
                     /locus_tag="IV356_002477"
                     /inference="COORDINATES: protein motif:HMM:NF018513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HAP9016122.1"
                     /translation="LWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKIIKEAIPSLLLI
                     VIIIGGILTGIFTAVEASAIAVIYKWVIRF"
BASE COUNT         3107 a         2220 c         2008 g         3162 t
ORIGIN      
        1 aaatacctaa tgacatcaag atcggcaaca caataactgc aatagaaatc actggtccga
       61 ttcctgtcat cgacatgaat ataacagcgg ttacaataca tagtaagctc atcgtgattc
      121 ttggcttgtc ccctccaagt tcaactacct ttcgaatcag ggtagctgcg attccgctat
      181 ctactagaac acgcccgaaa aaggcaccaa agaagacatt taccaagatc gatttggcgt
      241 actcagctgg ccccgtcgta tagatatgcg tcaacacatc aattactcct tgcccttcca
      301 tcgccgagtt tggtgaaaac gtgtttccga ctagcgctaa tcccatccat acagtagcca
      361 tgatgacaaa agccgaccat caagttgtag ccttttacac agtaccagac catgaaaaag
      421 aatgagataa ctaacaaaat accaataata atatcactca tgttattcct ccgtccattt
      481 tgtttttctg ataagcaaac taatatatca gtcaaactca ttctaactta tgtagttagc
      541 gctttcatta aaggatgacc ataaatgttc agttttcaat taaaaaacct taattatgtt
      601 attttagact tatacgttat tgtcctgttt catttgatgg aggattgtaa ataaaaaaag
      661 aggaaagaac ataacttttc gttatcttct ttcctcttta taattgttta gcttatttag
      721 ccaaagcttc ttttgcttgg tcagccaatg cagtaaatgc tgctgcatcg ttaacagcca
      781 agtcagctaa cattttacgg ttgatgtcga tttcagcaac tttcaaaccg tgcattaatt
      841 ttgagtagct caagccattc atacgagctg ctgcgttgat acgagcaatc cacaatttac
      901 ggaagtcgcg tttcttttga cgacgatcgc gatatgcgta gttgtatgaa ttcattactt
      961 gttcttttgc tgttttaaat aaagtgtgtt ttgaaccgta gtaacctttt gctaatttta
     1021 gcactctttt acgacgttta cgagttactg ttccaccttt aacacgtgcc atgtataatt
     1081 cctcctaata aaaataaatc ttcagattct gttatttgta cttcttattt catttttgct
     1141 agttgttggc gaatacgttt gaagtcgcca ctagaaacca tgcttgcttt acgcaattga
     1201 cggcgttgtt tttttgtttt gccgtggaaa cggtgacttg taaacgcgcg gaagcgtttc
     1261 aatccgcctt taccagtacg tttgaaacgt tttgctgatc cgcggtgtgt tttttgtttt
     1321 ggcatgacta tatttcctcc tcaaaatctt tcgttatccg actatcggct gtccaacagc
     1381 cagttagtca ttcaaattac ttactgtcgt ttttcggtgc cagcgtcaag aacatgctgc
     1441 gtccgtccat tttcgctttt tgttccactg ttgcaatatc cgcagtttct tcagctaagc
     1501 gattcaagac tttttgacca atttctttat gggtaatggc acggcctttg aaacggatag
     1561 aagctttcac tttatcgccc ttttccaaga acttacgtgc attacgaagt tttgtattga
     1621 agtcattcaa gtcgatcgta ggacttaagc gaacttcttt tacattgatc actttttgtt
     1681 ttttacgcgc ttcgcggtct ttcttttgtt gttcgaaacg gtatttaccg tagtccatga
     1741 ttcgcgcaac tggtggtttc gcaccagggg caactaacac aagatccaag tttgcttgtt
     1801 ctgcaatatt caatgcttct gcttttgtct taactcctaa ttgctcacca tctgaaccga
     1861 tcaatcgtaa ctctcgtgca cgaatgccgt cgttaaccat catatccttt gctatggtca
     1921 ttcacctcca aatattatga gagaaagaaa agcttaccga ataaacggca ataaaaaaac
     1981 gagttctctt acagaacccg cgcgtacttc acctaataga accagtgaaa actatctagc
     2041 ccagtgacat tatcaactaa ggcgagaagc gggtgcttct gcttttattt ctcaaccatt
     2101 atagtatagc aaaaactaat ctttttgtca atgtttttca tacagtttgt cttccttttc
     2161 tgaaaatgat tagattagca ggctttctag cagtgattcc cgcttctttg ctatactaaa
     2221 gaaaaacgag gtgaacccac atgaaaaaaa tcgaacctat tccaccttct cttcctcttc
     2281 ttacaaaggg agagttttat ttagaagatg aggagatctt ctctggtctt ctgatcaacg
     2341 gaggtaacca aagctatctc gatgccaaaa atatggtatt aagagagagt catatccaaa
     2401 aacttacgat gcaaaaaaca ggtttacgtc attttgaatg cagtaatgtc atttttgaaa
     2461 aatgtgattt ttccaatctg gagtggattg gtggcagttt ccaccaagtc gtgtttcatc
     2521 aatgtaaatt aacaggtacg aattttgccg aaagttatct tcgagactgt actttcactg
     2581 attgtattgc ttcgatggct tcctttagta gtacaaactt gaaagctgtc tccttcgatc
     2641 attgtcaatt agaagacagc gaattttatg aggtcacttg gaaaaacctt tttttgtctg
     2701 acaatcagtt aaccggttcg aactggtttc gaacttctct gaagggatta gactttacga
     2761 ctaatttctt cacaacaatc gctttatctc aagattcttt ggcgggacta atcgtcaatc
     2821 aagagcaagc acttgtgatc gcccaagccc ttggtttgca gatcaaagac tagatcaacg
     2881 aatccgccgc cacagtgcaa taagcatcca aatagataag accaaactga tgatcaaggc
     2941 gatttcccat ccgaaaacgg aatgggtaaa gggtaactgg agattcattc cgaagaatcc
     3001 tgtcacaata gttggaacgg tcaagatcag cgaccagacc gtcaaaaatt tcatcgtgtc
     3061 attcaagttg ttattcagca aattattata agtgccagag agctggtcta aaatctgcga
     3121 agctaagttc gtcatttcaa ctgcttgtcg tgcttcgatc agtgcatcgt ccaactcttc
     3181 tttttccttt tctgacaact tgcgataaat agccagtgcc ttgatttgtt ctaaaagtac
     3241 tacattttgt tttgttcctg taactaagta aaccaaaccg atctctaaat ctgaaagttg
     3301 cagcagattc ttgttcgttg ttttttctct taatttcaga ttaagccgct gacgttcact
     3361 attcacttcc tcgattaaag gaaaaaagga atcagaaatc aaaaacaatg tacgaaacaa
     3421 taaactgtat acactcatgt ctggcatccg ttccaaaagc gatcgaatta gtcgaatcac
     3481 gtactcggta ttcggcgtgg taaatgtaaa caaaccgtct tcttttaaaa taaaagcgat
     3541 aggactagtt tcataatgat tatcgacttt ttgctggtgc ggaacatttg atacaagcag
     3601 taacgcttca tcaaaagaat cgtactctac gcgcgcccgt tcatttttat ctagagaata
     3661 agtcagcatc tcgtcactaa tgccatattc ttcttttaag tttttaacag ctagcacatc
     3721 gttttgctgt acattgatcc aaaaattacg gtcttgatta aaatagtgtt tttcccgcat
     3781 actctatcct cctgacattt gtttccagta taaagaaaaa agtcgctcaa ataaaggttt
     3841 accctttatt tgagcaactg taaatcaaat ggatactttg gtttggcgaa tctctgctaa
     3901 tttttcttcg atcattttca agacttcttc ttttgcttga ggatcttcca caaaattata
     3961 gcggtctcca tcgatttgga tttttggact ttctttgtat tcttcatacc attgatcata
     4021 acgtctgttc aattctttgt aataatcgta tagacttggg tcaaaggaca attgttcata
     4081 cgaacgacca cgtttttcga tacgctctaa catcgtatca aaagatacac gaatatgaac
     4141 taataaatcc ggatgttttt tatgggcagc atagggaagt tcttccatca tgttttccag
     4201 cagttcatca tacacacaaa cttctgtttc tgttgctctt cctagatctg catttagatg
     4261 gaaaagcagt gaatcttcat aaatcgaacg gtccaataca ttattgtcat ctttcattgc
     4321 ttgtttgatg cttgcaaaac gtttattcaa aaaataaatt tgcagcaaaa aagcatactg
     4381 ttcagggttt gcataaaata agggcaagac ttcattatca tcaatcgatt cataaaatgc
     4441 ctgactatca aagtgttcag ccatcatttc tgttaaactt gattttccgg caccaattgt
     4501 acctgctaaa acgatcacgc tcatttacct ccagctcact tcatcactaa atattgtgtt
     4561 taactccaac cttttttaaa tataccccca atatctagta gtgtcaattg tattttttct
     4621 agtcaaagaa gaaaaaaagt caaaaaattc ttaagaaaaa agtgtttttt ctttagaaaa
     4681 cgtattctta gttttacttc tgagatggtt ttagtaaaat aaaggaggaa tgttttttga
     4741 gacccttagt ggacaaaaaa attcgtgaag cagcgcaact cgttttgggc gctttatttt
     4801 ttgcttaaaa atcactttta cgtgagaagg agttagatta tggcaaacta tggccaagga
     4861 gaatcaagcg gaaagatcat attgatgggc gagcacgcgg ttgtttatgg agaaccagcg
     4921 attgcctttc ctttctatgc aacaaaagtc accgcattcc ttgaagagct ggatgcaatg
     4981 gacgatcaac tggtttcttc ctactattca ggaaatttag ccgaagctcc tcatgcatta
     5041 aaaaatatca aaaaattatt cattcactta aaaaaacagc atgacatcca aaaaaacttg
     5101 caactgacca ttgaaagcac gattcctgct gaacgtggaa tgggatcaag cgctgcagtc
     5161 gccacagcag tcactcgtgc tttttatgat tacttagcat ttcctttgtc tcgtgaaata
     5221 ctattagaaa atgtccagct ttcggaaaaa atcgcccacg gtaatcctag tggaatcgat
     5281 gcagccgcta ctagcagctt gcagccgatt tattttacaa aagggcatcc ttttgactac
     5341 ttttctttga acatcgatgc ttttttgatt gtcgctgata caggaatcaa aggacaaaca
     5401 agagaagccg tcaaagatgt cgctcacctc tttgaaaccc agcctcatga aactggacaa
     5461 atgatccaaa aattaggata cttgacgaag caagcaaaac aagcaatcat tgagaattca
     5521 ccagaaacgt tggcacagac aatggatgaa tcacagtcac ttctggaaaa gctgacaatc
     5581 agcaatgatt ttcttaatct attgatccaa acagcaaaag ataccggggc attgggtgcc
     5641 aaattaactg gcggtggacg cggtggctgt atgattgcat tagcacaaac aaaaacaaaa
     5701 gcccaagaaa tcagtcaagc acttgaagat gcgggtgctg ctgaaacttg gatacaagga
     5761 ttaggagtac atacctatgt ttaaaggcaa agcacgcgca tataccaaca ttgctctaat
     5821 caaatattgg ggtaagaaaa atgaagaact catccttcca atgaacaaca gcctttcgtt
     5881 aacattggat gcattttata cagagacaga agtcatcttt tctgatagct atatggtaga
     5941 tgaattttat ctagatggca ccttacaaga cgaaaaagca acaaaaaaag tcagtcagtt
     6001 tcttgacctt tttcgtaaag aagccggcct ctcactaaaa gcttcagtaa tcagtcagaa
     6061 tttcgttcct accgcagctg gattagcctc ctctgccagc gggctagctg ctttagcagg
     6121 agcttgcaat actgctctta agcttggatt agacgatctc tctctttcaa gatttgctcg
     6181 acgcgggtct ggttcagctt gccgaagtat tttcggtggt ttcgttgaat gggaaaaagg
     6241 ccatgacgac ttaagttctt acgctaagcc agtcccttcc gattctttcg aagacgattt
     6301 agcaatggtt ttcgttttga tcaacgacca gaaaaaagaa gtgtccagca gaaatgggat
     6361 gcgtcgaaca gtcgaaacat ccagttttta tcaaggctgg ttagattccg ttgaagggga
     6421 tctatatcaa ttgaaacaag caatcaaaac aaaagatttc caacttctcg gagaaacgat
     6481 ggaaagaaac ggactaaaaa tgcatggaac gactttagct gcccagcctc cattcactta
     6541 ctggtctcct gacagcttaa aagcgatgga tgcggtgcgg caattgagaa aaaaaggcat
     6601 tccatgctac tttacgatgg atgctggccc taatgtcaaa gttttagtgg aaaacagcca
     6661 tttatctgag gtacaagaaa catttaccaa attatttagc aaagaacaag taattactgc
     6721 ccatgctggt ccaggaattg cgattattga ataaagggag atttttatga ttgaagtatc
     6781 tgcaccaggc aaactctata ttgccggaga atatgcagtt gttgaaacag gacatccagc
     6841 agttatcgct gcagtcgatc aattcgtaac agtcactgta gaatccgcac gaaaagtcgg
     6901 aagtatccaa tctgcacaat atagtgggat gcctgtacgt tggacaagac gcaacggaga
     6961 attagtttta gatattcggg aaaatccttt tcattatatc cttgctgcta ttcgtttgac
     7021 tgaaaagtat gcacaagaaa aaaacattct tttatccttt tatgatctga aagtaacaag
     7081 tgagttagac agttcaaatg gccggaaata tggattgggt tctagcggtg ccgtgaccgt
     7141 tgcaacggtc aaagccttga atgtttttta cgcgttgaat ttatctcaat tggagatttt
     7201 caagattgca gcactagcca atttagcagt tcaagataat ggttcctgcg gcgacatcgc
     7261 tgctagctgt tatggtggct ggatcgcttt ctcaaccttc gaccatcctt ggctccaaga
     7321 acaagaaact cagcattcta tcagtgagtt acttgccctg gattggccag gtctatccat
     7381 tgagccattg attgctcctg aagatttacg tttattgatt ggttggacgg gtagccctgc
     7441 ctctacttct gatttggtcg atcaagttca ccgttcgaga gaagacaaaa tggtggctta
     7501 tcagcttttc ttaaaaaaca gtacagaatg tgtcaacgaa atgatcaaag ggtttaaaga
     7561 aaataatgta acgttgatcc aacagatgat tcgaaaaaac cgacaattac tgcatgattt
     7621 atctgcaatc actggggtcg tcatcgaaac gcctgctttg aacaaattgt gtaatttagc
     7681 tgaacagtat gaaggagccg caaaatcttc tggtgcaggt ggtggcgatt gcggaatcgt
     7741 aattgttgac cagaaatctg gcatccttcc tttaatgagt gcatgggaaa aagcagaaat
     7801 cactccactg ccgttacatg tctatagcga tcaaagaaag gaaaaccgat gaatcgaaaa
     7861 gacgaacatg tttcactagc taaagccttt catgataaac aaaaaaacga atttgacttc
     7921 gtacggatca tccataaccc tttgccgcaa atagcagttt ctgatgtcga tctaagtaca
     7981 caggcagttg ggtttacact aagcagccca ttttatatca atgcgatgac tggcggaagc
     8041 gaaaaaacaa aaaaaatcaa ccaagatctt gcaatcgtcg caagagaagc agatttgatg
     8101 attgccactg gttcagtcag cgctgccttg aaagaccctt ctttagccga tacttatacg
     8161 attatgcgac aagaatatcc tcacgggaaa atcattgcca acatcggtgc agggacttct
     8221 gtcgaaagag cccaagaagc tatccgattg tttcacgcag atgccttaca gattcatttg
     8281 aatgcacctc aagagttggt tatgcctgag ggagaccgtg attttaccaa ttggaaagta
     8341 cttattcaag agactcaaac agccattgac gtccccctca tcgtaaaaga agtcggtttt
     8401 ggcatgacaa gagaaacgct caatgatcta gctgctttag gagttcatac agttgatatc
     8461 agcggtcgaa gcggaacaag cttcacccag atcgaaaacg cccgtcgctc caagcgggaa
     8521 ctgagttatt tagctgactg ggggcaatcg acagtctctt cattgcttga agcaaatgaa
     8581 gcagacactt ctatggaaat cctagcctcc ggaggtatcc gcaatgccta tgacatattt
     8641 aaagcccttt gtctcggcgc aaatgcagtg ggtacttcag gaaccgtact gacgcatctg
     8701 atgaatcacg gcgtagaaga aactattata ctgatgaagc aatggcaaga agagcttcgt
     8761 ctgctttata ctatggtcgg cgcaacgaat accgcggccc tacaccaaca atcactgatc
     8821 ttttccggac cagtgaagga ttggtgcgaa gcaagaggga tcgacttagt gaagtatgga
     8881 agacgcacag aaaagagcgt gggacaaaag taaagaacac ttttatccca cgctctaaac
     8941 acgtataaac ggcggaagca aaagcaactc cttcggaaat aagctgaaat tcacaaaaat
     9001 ttgaaaagca attttcgtga attccttctt atttcttgga gttaaacgct tctgtcccag
     9061 cctctttttt cgaataaatg atgtttaatc agctgtcctt cggtattcgt tcaagccgct
     9121 gatttcacaa cctctccact aaacggtgta ctaaagctct tttaaggttg ttttccgata
     9181 taggcaagta tgcctccgtc cacatacaag acatggccgt taacgaaatc agatgcgcta
     9241 gaagccaaga agacagatgg tccagccaaa tcgattggct cgccccagcg tgctgctggc
     9301 gtacgtccaa cgataaattg atcgaatgga tgacgttcac cgttttcttg tgtttcgcgt
     9361 aatggagcag tttgcggtgt agcaatataa cctggtccaa ttccattaca ttggatattg
     9421 tattgaccgt attcagaagc gatgtttttc gtcagcattt ttaatccgcc ttttgccgca
     9481 gcataagcac tgaccgtttc gcgtcctaat tcactcatca tggagcagat attgatgatt
     9541 ttaccgccgc ctttttcgat catatcccga ataactgctt ttgaaacgat gaatggggca
     9601 tttaaatcca cgtcgattac ttggcggaag tctgccgcat ccatttcgat catcggtgtc
     9661 cgtttgatga tccctgcatt gttgactaga atatcaactg aacctacatc ttctttgatc
     9721 tgttgaacca tcgcttgaac cgcttcttca tcggtcacat cgcagacata accttttgca
     9781 tcgatgcctg cttctttata atgcgctata ccttcatcaa ctgattcttg attcaagtta
     9841 ttaaatacga tttttgctcc tgctgtagct aaagagcgtg caatctcaaa tccaatacca
     9901 tagacagcac cggtgactaa tgctactttt ccatctaaac gaaacatatc catactaaat
     9961 tccatcattt tctctccctt atgcttattt taattgatcc atttgcacca tatccatgtc
    10021 tgtataggtg atattttctc cgcacattgc ccagatgaat gagtaattgc ttgtacctac
    10081 acctgaatgg atcgaccagc ttggcgaaat aatggcttgt tcattgtcta cgactaaatg
    10141 ttttgtttca tctggtttgc ccatcatatg gaacacacgt gtatcttcat tggcataatc
    10201 aaaatagaca taagcttcca tacgacgttc atgtgtatga caaggcatcg tattccaagc
    10261 acttcctggt tctaaaatcg tataacccat ttataaatga cagctatcgc tgaagcttct
    10321 actgctgtaa atatccccgt caagatacca ccgataatga tgacaatcaa tagaaggcta
    10381 ggaatcgcct cttttattat ttttccagca tgagccatct gtcctttttc gacaacaggg
    10441 tatttattct ttttagcaac gatgaatgct actagcatga ttcctagcgc ccacaaa
//
LOCUS       DACDLM010000088        10282 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.090, whole genome shotgun sequence.
ACCESSION   DACDLM010000088 DACDLM010000000
VERSION     DACDLM010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.090"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(47..871)
                     /gene="iolB"
                     /locus_tag="IV356_002478"
     CDS             complement(47..871)
                     /gene="iolB"
                     /locus_tag="IV356_002478"
                     /EC_number="5.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-deoxy-glucuronate isomerase"
                     /protein_id="HAP9016123.1"
                     /translation="MEKTLKHQPLNKELAPGVKQIQNIRQSNSALSYIEFQILELEKG
                     ASYKETGSQQEVCIVILTGKIKVKAADTWYEDLGTRESVFEKIPTDSIYLPAEHSFEL
                     VATTDNVRLALCYSPAKKALPISVIRAEDNTVEERGLYQNKRLVHNILPDNVDTASSL
                     LVVEVYTEGGNFSSYPPHKHDQENLPHESFLEETYYHELDPEQGFVFQRVYTEDRSLD
                     ETMTVEHQNVVEVPKGYHPVGVPDGYTSYYLNVMAGPERIWKFHNEKKHEWILQRK"
     gene            complement(910..2826)
                     /gene="iolD"
                     /locus_tag="IV356_002479"
     CDS             complement(910..2826)
                     /gene="iolD"
                     /locus_tag="IV356_002479"
                     /EC_number="3.7.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002397168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3D-(3,5/4)-trihydroxycyclohexane-1,2-dione
                     acylhydrolase (decyclizing)"
                     /protein_id="HAP9016124.1"
                     /translation="MEKTVCLTTAQALLKFLNQQYISIDGKETPYVEGIFHVYGHGNV
                     LGIGQALELEPGHLKSYSGKNEQGMAHAATAFARQNLRKKIFAVSTSVGPGAANLLTA
                     AGTAFANNIPVLFLPADTFATRQPDPVLQQLEHASSVAFSTNDAFQAVSRYWDRINRP
                     EQLMSALLRAFEVMTNPATMGPATICLPQDVEAEAYAYPEEFFKKRVHYIDRRIPTAR
                     ELAEASQRIKASKRPVIIVGGGCKYSEAGEILEQISRDCQIPLVETHAGKSTVSWDFK
                     NNLGGMGILGTSAANKAVQQADLIIGIGTRYTDFTSASKSIFNFEQAKMMNINVSRQQ
                     AAKLEAFQVVGDAKATLEQLAPMIEGYQTAYGEKIDELKEEWISERNRLKAAHFKRKD
                     FTPEIKDHFSQEILNEYADALATNLTQTEVFIHLNDFVDEDAIVIGSAGSLPGDMQRL
                     WNPVKENTYHLEYGYSCMGYEIAGAMGVRMARPEQEVYALVGDGSFLMLHSELVSSLQ
                     YDKKINIVLFDNSGFGCINNLQMDNGGASQGTEFRNTKDEIMNIDYAKVAEGYGAKTY
                     RVSSIAELQAAVEDAKKQTRSTLIEIKVLPKTMTEGYDGSWWNVGISEVSGKAAMQEA
                     YKAKQAKLATIRKY"
     gene            complement(2837..3871)
                     /gene="iolC"
                     /locus_tag="IV356_002480"
     CDS             complement(2837..3871)
                     /gene="iolC"
                     /locus_tag="IV356_002480"
                     /EC_number="2.7.1.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018593001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-2-deoxygluconokinase"
                     /protein_id="HAP9016125.1"
                     /translation="MSYIKFDQSKEFDLLLLGRVAIDFNPAYNDQVKEEFKPLKKVHM
                     FEKFVGGSPANIAVGVTKHGMKAGFIGTVSDDQFGEYVIDYFNEQGIDTSQISKAQHG
                     EKLGLTFTEMLSSKESNILMYRNQAADLQLSVEDIDEDYLKRSKALLISGTALAESPS
                     REAVIKAVMLAKRNNVKIIFDIDYRAYNWKNNDDISIYYSMIAKESDIIMGSREEFDL
                     TEKLIQPNMSDNESAAFWHSCGAEIVVIKHGMKGSTAYTADQQQFSIKPFPVEARKGF
                     GGGDGYGSGFLYGLFEGWEIIDCLEFGSAEASMMVKSNNCSDSLPTTQEVKDFITLEK
                     EIYGEMIARI"
     gene            complement(4028..5044)
                     /locus_tag="IV356_002481"
     CDS             complement(4028..5044)
                     /locus_tag="IV356_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016633586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAP9016126.1"
                     /translation="MAGTIKEIAEKAGVSRGTVDRALNDRGRINPEVAERIRAIAKEM
                     NYVPKKKKVIKETTLKLGIVTQLAKSSFMIPIRSGLESIIGDLKKRNIDCFLEEVDGV
                     DEAAQLQALDRLVELGVKGIAIMPVDSDGIREKINQLTDQGILIITFNSDILGTNRQC
                     FVGMDNFKSGKTAAGLLGMLTKGKGKVLAITGYFGNSVNSLRVAGFVEELKESFPELE
                     LTGVQSSFDSSAEVEKILSNTLENYSNLDGVVVFSGGQAGIARALEKIDESKRPFVII
                     YDLTKNNIEMLKNDQVDFLIDQDGFVQGYRSLLMLANQLQNNKTVTKDALFTDIIIKT
                     KYNI"
     gene            complement(5146..5343)
                     /locus_tag="IV356_002482"
     CDS             complement(5146..5343)
                     /locus_tag="IV356_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016127.1"
                     /translation="MKFICLSCGEKESIPMDVVKFLDDADIANDPNNPPQFTCEKCGK
                     EMYPEYYRNALGIEFKISDVQ"
     gene            complement(5315..6634)
                     /locus_tag="IV356_002483"
     CDS             complement(5315..6634)
                     /locus_tag="IV356_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011674482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /protein_id="HAP9016128.1"
                     /translation="MKANILEAIFFDEHHNWDNFVEKYGRKIRLVVKREVNKFRYCGD
                     IQKGYRLFVCEGCHQTKFVPLKCRGKFCPTCATGESQRWSAVVANDMFKVTHRHVIFT
                     IDEGLREIFMMENYRDSLLKGLMDEAAKIILAYFEKRKVKAGIVATIHTFGSKLEFNP
                     HVHMVVTMGGLTRDGSWEEYDYLPFSMLRKYWKNAVLKLIRRTLGEWDKQRVQSRLQA
                     AYKNNGEGFYVNAPKRSRTNLKSLLQYISRYMKRGPIALSRILMYDGDTVMFNYMDKR
                     TNTKETMTMSIDEFIAALIRHIQNKNFKTIRRYGIYSRRIKTLMKKVMKEYQKRVKKL
                     FINLNEALRPKSWEERITEEFGENPLECSCCGEYYEFVGMSVRKNGRLVIKYAKDNHA
                     KRFMREENRKIDQKEFRQQYEEEKEKTFKAIRWDWERQREIYMSKLW"
     gene            complement(7375..8355)
                     /locus_tag="IV356_002484"
     CDS             complement(7375..8355)
                     /locus_tag="IV356_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HAP9016129.1"
                     /translation="MLFLKKEDIIKSFSMREAIDADKKALSLYSAGKASVPLRTNIDV
                     PKSNGQSLYMPAYVEGGEGALGVKIVSVYPENIKKNLPSVPATMIVLDPETGMVSACL
                     DGTYLTQLRTGAVQGAATELLAREDAKIGALIGTGGQAQSQLEAMLTVRKLEEVRIFD
                     IDFERASQFAEKMMQQFSVTMRPTKTSQECVEGADIITSVTTSKRATFSAEWVKKGAH
                     INGVGAYTPEMCEIPREIIKAADVVIFDTMDGVLKEAGDFISPLQDGYIQRDSYHGEL
                     GQLINEELIGRTSGEQITIFKTVGSAVLDVVVATEIVKKAKENNLGKLIF"
     gene            complement(8368..9246)
                     /locus_tag="IV356_002485"
     CDS             complement(8368..9246)
                     /locus_tag="IV356_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HAP9016130.1"
                     /translation="MIRNILLTLIVAINLYFIIYFLRDLFKNKQNFKEEPGDMRLLPF
                     TSFIIFFLSTFGVSDFAIGTVLYPKLKWVSMKKLPGTLNTQCVVPVAVMALSYITAIN
                     VGIKTLAVCIICQIIGAYLGPRFVVKLPEKTIKLFVGIGLVIAALLIFAGQMNWIPSN
                     GTASELYGGKLILAGFLLFVYGALNNIGIGSYALTMVTVYLLGLNPVAAFPIMMGACT
                     FSVPIGSVQFIKFNEYSRKITLFTSTFGVLGVLVAVFLVKSLDTYILKWIVILVLLYS
                     AYTMLGSQLKKVTAAN"
     gene            complement(9262..10062)
                     /locus_tag="IV356_002486"
     CDS             complement(9262..10062)
                     /locus_tag="IV356_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HAP9016131.1"
                     /translation="METIIQIMKKYDFSEMETRVYTTLLEKGNLTGYEVSKISGVPRS
                     KVYNILEKLLKKNLIVVNKSEPKLYHAISANEFLEKLEKSVKNDLSFLTKNLGMIKEK
                     DEEEMLWKVDGIEYVLDKVEHLVKNAKESLLIQVWHENFTDSLLKALQQAEKRVDKFV
                     LILFSSTHEYDLPLEKYYIHGFETDKLADFGARWINIVADEQEVVFGTINEELQSTDV
                     TWTKNHAMVNLAKEYVKHDAYTLKVIAESPEELKAKYGEGFEGIRKIY"
BASE COUNT         2802 a         2369 c         1728 g         3383 t
ORIGIN      
        1 acctaactaa acctaactaa actttatgta tctaacagct taataactac ttgcgctgca
       61 agatccattc gtgtttcttt tcattgtgga atttccaaat tcgctcaggt cccgccatca
      121 catttaaata gtaggaagta tacccgtcag gtaccccaac tggatgatag cccttaggaa
      181 cttcgacgac attttgatgc tctaccgtca tcgtttcatc tagtgaacga tcttccgtgt
      241 agacccgctg gaaaacaaat ccctgctctg gatcaagctc atggtaataa gtttcctcta
      301 aaaaagactc atgtggcaga ttctcttgat cgtgcttatg aggaggatag ctggaaaaat
      361 taccgccctc ggtataaact tcgacgacca gcaggctgct ggcagtatcg acattatccg
      421 gtaaaatgtt gtgaacaagt cgtttattct gatagagtcc acgttcttcg acggtattat
      481 cctccgcgcg aatcacactt atcggcaaag cttttttcgc tggtgaatag caaagcgcca
      541 atcggacatt gtctgtagtt gccacaagtt caaacgaatg ctccgccgga agataaatac
      601 tgtcggttgg aattttttca aaaacagatt ctcgtgttcc taaatcttca taccaagtgt
      661 ctgctgcttt aaccttaatt tttccagtca aaatgacgat acagacctcc tgttgactgc
      721 cggtttcctt gtaagaagct cccttttcca gctccaaaat ctgaaattcg atataactca
      781 aagcagaatt agactgccga atattttgga tttgttttac tccaggtgcc agttctttgt
      841 ttaatggttg atgcttcaat gtcttttcca atcaatccac tccttatttt caatcacaaa
      901 aagcaatatt taatactttc tgatagtggc aagtttcgct tgtttggctt tgtaagcctc
      961 ctgcatggct gctttacccg atacctctga gataccgacg ttccaccagc tgccgtcgta
     1021 gccttctgtc atggttttag gaagtacctt tatctcaatc aacgtcgatc gcgtttgctt
     1081 cttcgcatcc tcgaccgctg cttgtaattc tgcaatcgag cttacacgat acgtttttgc
     1141 accatagcct tcagcaactt tggcgtaatc gatgttcatg atctcgtcct tggtatttct
     1201 gaattcggtt ccttggctag ctccgccatt atccatctgt aaattattga tacagccgaa
     1261 accagaatta tcgaaaagta caatgttgat ttttttatca tattgcaaac tagaaaccag
     1321 ctcgctatgc aacatcaaga aactgccatc gcctactaag gcatagacct cttgttctgg
     1381 tcgagccatt cttacgccca tcgcaccagc gatttcatag cccatacaag aataaccgta
     1441 ttccaaatga taggtattct ccttcacagg gttccataag cgctgcatat cccccggcaa
     1501 tgaaccggct gaaccgatca cgatcgcatc ctcatcaaca aaatcattta aatgaatgaa
     1561 gacctctgtt tgcgtcaaat tcgtagccaa cgcatcagca tattcattca agatttcttg
     1621 agaaaaatga tctttgattt ctggcgtaaa atctttacgc ttaaaatgcg cggcttttaa
     1681 ccgatttcgc tcactgatcc attcttcctt cagttcatcg atcttctcgc cataggcggt
     1741 ttggtaacct tcgatcattg gggcaagctg ctccaaggtc gctttcgcat caccaaccac
     1801 ttgaaaggct tccagcttag cggcctgttg tctgcttacg ttaatattca tcattttcgc
     1861 ttgttcaaaa ttaaaaatac ttttagaagc tgaggtaaaa tcagtgtagc gtgtgccgat
     1921 ccctatgatc agatccgctt gctgcacagc tttattagca gccgaagttc ccaaaatccc
     1981 cattccgccg agattgtttt taaaatccca cgaaacagtc gatttacctg cgtgcgtttc
     2041 aactagcgga atctgacaat ctcttgagat ttgctcaaga atctcaccag cctccgaata
     2101 tttgcagccg cctcctacga tgatgacagg tcgtttactg gcctttattc gttgactcgc
     2161 ttcagcaagc tcacgagcgg tcggaatcct gcgatcaata taatgtactc tttttttgaa
     2221 aaattcctcc ggataggcat aggcttctgc ctccacgtcc tgcggcaaac aaatcgttgc
     2281 cggacccatc gttgccgggt tcgtcatgac ttcaaaggcc cgcaataacg cggacatcaa
     2341 ctgctctggt cgattgatgc ggtcccagta gcgagaaacc gcttgaaatg catcatttgt
     2401 cgaaaaggct acactgcttg catgttccag ctgctgcaag accggatcag gctgacgtgt
     2461 agcaaacgta tccgccggta aaaaaagtac ggggatatta tttgcgaatg ccgtacccgc
     2521 tgctgttaac agattggccg cgcccggtcc aacagatgtt gatacggcaa aaattttctt
     2581 gcgtaaattc tgtctggcaa aggcagtagc cgcatgggcc attccctgct cattttttcc
     2641 gctataactt ttcaaatgtc cgggctctaa ttccagcgcc tgaccgatcc ccaaaacatt
     2701 tccgtgacca tagacatgaa agataccttc aacataaggc gtttctttgc cgtcgatgct
     2761 gatgtattgt tgattcaaaa attttagtaa tgcttgtgct gttgttaaac aaaccgtctt
     2821 ttccattttt ttcaccttaa atccgagcga tcatttcgcc gtatatttct ttctccaatg
     2881 taataaaatc ttttacctcc tgagtcgtcg gtaaagaatc tgaacagtta ttgcttttga
     2941 ccatcattga tgcttccgct gagccaaact ctaaacaatc gatgatctcc cagccttcga
     3001 ataaaccgta taagaaaccc gagccgtaac catctccgcc gccaaagcct ttgcgtgctt
     3061 ccaccggaaa cggcttgatt gaaaactgct gctgatcggc cgtataagca gtcgatcctt
     3121 tcattccatg tttgattacg acaatctcag caccacaact gtgccaaaaa gcagcgcttt
     3181 cattatctga catgttaggc tggatcaact tctcagttag atcgaactct tctcttgaac
     3241 ccatgataat gtctgattcc ttagcaatca tcgaatagta aattgaaata tcatcgttgt
     3301 tcttccagtt ataagcacgg taatcaatat caaaaataat tttgacatta ttccttttcg
     3361 ccagcatcac tgccttgatt acggcttctc tggacgggct ctctgctagt gcagttcctg
     3421 agattaatag tgcttttgac cgtttcaagt agtcctcatc aatatcctca acgctaagct
     3481 gcaggtctgc ggcttgattt cgatacatca aaatattact ttcctttgat gagagcattt
     3541 cggtaaaagt cagccccagc ttttcaccat gctgcgcttt gctgatctga gacgtatcga
     3601 tgccttgttc attgaaataa tcgatcacat attcgccaaa ctgatcgtcc gagactgttc
     3661 cgataaaacc agctttcatg ccatgtttag taacacccac agcaatattg gcaggagatc
     3721 cgcccacaaa tttttcaaac atatggacct ttttcaatgg tttaaactct tctttgactt
     3781 gatcattgta ggcaggatta aaatcaatag cgactcttcc taaaagcagc aagtcaaatt
     3841 cttttgattg gtcaaacttt atataactca atatatccac ctctttatcc gttcttctat
     3901 ttctgaggca agtatagcac gccaaaacaa agcgtgcaat atttatttta gaacgcaata
     3961 ttgcgtgctg tttgaaaatg acggcaaaaa aaacgtgaat cgccttacat cacgattcac
     4021 gcctagatta aatattgtat tttgtcttaa taattatatc agtaaatagc gcatcttttg
     4081 taaccgtttt attattttgc agctgattcg ctaacatcag taatgaacga tagccttgaa
     4141 caaatccatc ttgatcgatt agaaaatcaa cctgatcgtt tttcagcatc tcgatattgt
     4201 tcttagtcaa atcataaatg attacaaagg gccgcttgct ttcatcgatt ttttccaacg
     4261 ctcgggcaat tcccgcttgt ccgccagaaa agacgactac gccatctaag tttgaataat
     4321 tctccaaggt gttgcttaaa atcttttcaa cctcagcact cgaatcaaag ctgctctgaa
     4381 cacccgtcag ctccagttca ggaaacgact ctttcaattc ttcaacaaag cctgccaccc
     4441 gtaagctgtt gacgctattt ccaaagtagc cggtaatcgc tagaaccttg ccctttcctt
     4501 ttgtcagcat acctaacaat cccgcagccg tttttccgct tttgaagttg tccatcccaa
     4561 caaaacactg tcgattcgta ccaagaatat ccgaattaaa ggtaatgatg aggatgcctt
     4621 gatcggtcaa ttgattaatt ttttctctga taccatcact atctactggc atgatcgcga
     4681 tcccttttac tccaagctcc accaatcgat ccaacgcctg cagctgggcc gcttcatcga
     4741 ccccgtctac ctcttctaaa aaacaatcaa tgtttcgctt ttttaaatcc ccgataatag
     4801 attccagacc tgatcggatc ggaatcataa aagaagattt cgccaattga gtgacaatcc
     4861 ccagcttgag cgttgtctct tttatgacct tctttttctt tggaacatag ttcatttcct
     4921 tggcgattgc tctgattctt tctgcaacct caggattgat ccttcctcga tcgttcaatg
     4981 cccgatccac tgtccccctt gacactcctg ctttctcagc tatttcttta attgtacccg
     5041 ccatcttgcc tctccttttt tcctattgtg tttattttat cacaaaactt aagaaaacca
     5101 ccggagaatg aattctccgg tggacttttt gtatgattaa ccttcttatt gaacatcact
     5161 gatcttaaac tctattccaa gggcgtttct ataatattct ggatacatct ccttcccaca
     5221 tttttcacag gtaaattggg gaggattgtt cggatcattt gcaatatctg catcatctaa
     5281 aaattttact acatccattg ggattgattc tttttcacca caacttagac atataaattt
     5341 cacgttggcg ttcccaatcc cagcgaattg ctttaaaagt tttttctttt tcttcttcat
     5401 actgttgcct gaattctttt tggtcaattt ttcgattctc ctctcgcata aaccgctttg
     5461 catggttatc tttcgcatat ttaataacta accgtccatt tttgcgcaca ctcatcccaa
     5521 cgaattcata gtactcaccg caacaagaac attctaaggg attttcacca aattcttcgg
     5581 ttattctttc ttcccaggat tttggtctta aggcctcatt cagattgata aacagctttt
     5641 ttactcgttt ctgatactcc ttcatgacct ttttcattaa tgttttgatt ctacgactat
     5701 agattccata gcgacgaatc gttttgaaat tcttattttg aatatggcga atcagtgcag
     5761 ctatgaattc gtctatactc atggtcatcg tctctttagt attcgttcgt ttgtccatgt
     5821 agttgaacat gacagtgtcg ccatcataca ttaagattcg gcttaatgcg atcgggccac
     5881 gcttcatata acgactgatg tattggagta gtgactttag atttgtcctg ctccttttag
     5941 gagcatttac gtaaaaccct tctccattgt tcttgtacgc agcttgtaat cttgattgaa
     6001 ctctttgctt gtcccactca cctaacgttc gtctaattag tttcaataca gcatttttcc
     6061 agtattttct taacatagaa aaaggtaaat aatcgtattc ttcccaactt ccatctcttg
     6121 ttaagccacc catagtaaca accatatgaa catgcggatt aaattctagt tttgatccaa
     6181 aggtgtggat tgtagctact atacctgcct tcacctttct tttctcaaaa taggcaagaa
     6241 taatttttgc ggcttcatcc attagtcctt tcagtaagga atctcgatag ttttccatca
     6301 taaagatttc ccgtaacccc tcatcgatcg taaagattac gtgccgatgt gtcactttaa
     6361 acatatcatt cgccacaacc gctgaccacc tttggctttc acctgttgca cacgttggac
     6421 agaactttcc acgacatttc aagggaacaa actttgtttg atgacatccc tcgcagacaa
     6481 acagtcggta tcctttttga atatctccac aatatctaaa cttgtttact tcccgtttga
     6541 cgactagccg aatctttcgc ccgtatttct caacaaagtt atcccaatta tggtgttcgt
     6601 caaaaaagat tgcttcgaga atattcgctt tcatagtaat attttacttg ttcaaaaaca
     6661 aaatgaaaag ggctaaaaga ctggtagtgc agccttttta gcccttaact ttttatactt
     6721 tctttactgt ctaaaaaata tgcggcgcac agaacgcgcc gcatatcgga ctaagtttta
     6781 ttcaaatttg tcttcgccaa cacaatttga cgaagagcct tttctttcag gaagacttcg
     6841 gtaattttta ggagttctac ctattctttt aaccgtttat tctctttttc taagcgtgta
     6901 atttcatttc tgcgaatgga tttcatgact tcctctaccg agaaaagtac gttatccata
     6961 tttttcaact tcttgaactc atcaatacac gctattagag cgagcttcta gctatagact
     7021 aacttcttta acagaaaacc cttcttccgt taccagtttt acagcggtaa ttttaaatat
     7081 ttcatcaaat gaacgtcttg gcataatcca gatcttcgct ttctcttaat ttggtgtcaa
     7141 ttttagtata acccgtccaa cttatttttt aactaagtgc ccggtttttc ttgacaactc
     7201 cacccaaaag ttagattttt tggtctaagt tttagggtcg cttcattact agaattcaac
     7261 aagagatgtt ttttatttta tttaaattat ggggtcagtt tccatttgat tacaaacttc
     7321 tttgttttct ttttttaaac gcaataataa aggttttaat ttcagccttt ttaattagaa
     7381 aatcaatttt cccaaattat tttctttagc tttcttaacg atttctgtcg caactaccac
     7441 atctaataca gccgaaccaa ctgttttgaa gatcgtgatt tgttctccac ttgtccgacc
     7501 gatcaattct tcattgatca gttggcctag ttccccatga tagctgtctc tttgaatata
     7561 cccatcttgc agcggtgaaa tgaagtcccc agcttctttt agaacaccgt ccatggtatc
     7621 aaaaataaca acatctgcgg ctttgattat ttctcgtgga atttcacaca tttccggtgt
     7681 gtaagcaccg actccattga tgtgcgcacc ttttttgacc cactcagcag agaatgtcgc
     7741 acgttttgaa gtggtcacac ttgtaatgat gtctgctcct tcaacgcatt cttgactggt
     7801 ttttgttggg cgcatcgtta cagaaaattg ttgcatcatt ttttcagcaa attggctggc
     7861 acgctcaaaa tcaatatcaa aaatccgaac ttcttctaat ttacgaacgg tcaacattgc
     7921 ttctaattgt gactgtgctt gtccgccggt tccaatcagc gcgccaattt tagcatcttc
     7981 tcttgcaaga agttctgttg ctgctccttg aacagcgcct gttcttaatt gtgtcaaata
     8041 agtaccatcc aaacaagcgg ataccatacc cgtttctgga tccaatacga tcatcgttgc
     8101 tggtacactt ggtaagtttt tcttgatgtt ttcaggatac acggaaacga ttttgacacc
     8161 tagcgcgcct tcgccacctt ctacataagc aggcatatat aagctttgtc cgttgctttt
     8221 tggcacatcg atattggtgc gaagaggcac acttgccttt cctgctgaat acaatgacag
     8281 tgcttttttg tccgcatcga tggcttctct cattgaaaaa cttttgataa tatcttcttt
     8341 tttaagaaat aacatttgaa tcgctcctta attagctgct gtaacttttt ttaattgact
     8401 gcccaacatc gtatatgcac tgtatagtaa gaccaaaatc acgatccatt tcaggatata
     8461 ggtatctaaa gatttgacta ggaatacagc gaccaatacc cccaatacac cgaaggttga
     8521 agtaaaaagt gtgatttttc tgctgtattc attaaattta atgaattgaa cactgccgat
     8581 cggtactgag aaggtacaag cccccatcat aataggaaag gctgcaactg gattcaagcc
     8641 tagcaagtag acagttacca tcgttaacgc ataagaacca atgccgatat tgttcaatgc
     8701 accatagaca aagagtaaaa atcctgccaa gattaatttt ccgccataca attcactggc
     8761 tgttccgttt gatggaatcc agttcatttg tcctgcaaaa atcaacaatg cagcaatgac
     8821 caatcctatg ccgacaaaca gtttgatcgt tttctctggt aacttcacga caaatcttgg
     8881 tcctaaatat gcaccgataa tttggcagat aatacaaaca gctagtgtct tgatccctac
     8941 gttgatggca gtgatgtaag acaatgccat gacggctacc ggtactacac attgggtatt
     9001 caacgttccg ggtagttttt tcatgctgac ccatttcaac tttggataaa ggacggttcc
     9061 gatagcaaag tcggaaacgc caaatgttga aagaaagaag atgataaatg acgtgaaggg
     9121 caacagacgc atatcccctg gttcttcttt gaaattttgt ttgtttttga aaaggtctct
     9181 tagaaagtaa ataataaaat atagattgat tgcgacaatt agtgtcagca aaatattccg
     9241 aatcataaaa aattcctcct actagtaaat ctttctgatt ccctcaaagc cctcaccata
     9301 ttttgcttta agttcttcag gagattctgc aatcactttt agtgtatatg catcatgttt
     9361 gacatattct tttgctagat tgaccatggc gtggtttttt gtccaagtga catcggttga
     9421 ttgcagttct tcgttaatgg taccaaacac gacttcttgc tcatcggcga cgatgttgat
     9481 ccatcttgct ccaaagtcag caagtttgtc tgtttcaaaa ccatgaatat aatacttttc
     9541 taagggaaga tcatattcat gggtagaact gaataaaatc agtacaaact tatcaactct
     9601 tttttcagct tgctgcaatg cctttagtag tgaatccgtg aaattctcat gccaaacttg
     9661 aatgagcaaa ctttcttttg cgtttttcac caaatgctct actttatcca gaacatactc
     9721 gataccatca actttccaca gcatttcttc ttcatctttt tctttgatca tccctagatt
     9781 cttggtaaga aaagaaagat catttttaac acttttttct aatttctcta aaaactcatt
     9841 tgccgagatg gcatgataaa gtttaggttc tgatttatta acgacaatca aattcttttt
     9901 taatagtttt tccaaaatat tatatacttt cgagcgtggc acacctgaga ttttacttac
     9961 ttcatatcct gtaagattac ctttttctaa tagtgtggta tacactcttg tctccatctc
    10021 tgaaaaatca tattttttca tgatttgaat aatcgtttcc attgattaat cctcacttta
    10081 tttttagtag ctactacggt aacaactata aattcttttt gattatctgt caagagttag
    10141 ttcaataaca cacatataat aattagctta aaaacaatct ttttattaaa aagaaacatt
    10201 ataatatgaa tgtttgtgaa aaaataatac aacttagtca ttctttacaa cgatttatag
    10261 aaaaacaacc tctttaaata ta
//
LOCUS       DACDLM010000089        10126 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.091, whole genome shotgun sequence.
ACCESSION   DACDLM010000089 DACDLM010000000
VERSION     DACDLM010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10126
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.091"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            115..621
                     /locus_tag="IV356_002487"
     CDS             115..621
                     /locus_tag="IV356_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HAP9016132.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            638..1537
                     /locus_tag="IV356_002488"
     CDS             638..1537
                     /locus_tag="IV356_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HAP9016133.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            1624..2508
                     /locus_tag="IV356_002489"
     CDS             1624..2508
                     /locus_tag="IV356_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAP9016134.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(2700..2771)
                     /locus_tag="IV356_002490"
     tRNA            complement(2700..2771)
                     /locus_tag="IV356_002490"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2736..2738),aa:Arg,seq:ccg)
     gene            2831..4165
                     /gene="rpoN"
                     /locus_tag="IV356_002491"
     CDS             2831..4165
                     /gene="rpoN"
                     /locus_tag="IV356_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HAP9016135.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            4368..5405
                     /locus_tag="IV356_002492"
     CDS             4368..5405
                     /locus_tag="IV356_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SorC family transcriptional regulator"
                     /protein_id="HAP9016136.1"
                     /translation="MLDEIKMIESVAPDIIEVLQERYKILRNIYWMQPIGRRSLSESM
                     GITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSLENFMDQLLGTHQTEQQLA
                     EYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEGENIIAVMGGTTMAVVAEQ
                     LSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKANGNHRALYVPEQLSLATYN
                     SLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEKELVMLKQANAVAESFGYF
                     FNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAIRAYMKNAPKQTWLITDEA
                     AANEILKGVTL"
     gene            5446..6447
                     /gene="gap"
                     /locus_tag="IV356_002493"
     CDS             5446..6447
                     /gene="gap"
                     /locus_tag="IV356_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAP9016137.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            6557..7747
                     /locus_tag="IV356_002494"
     CDS             6557..7747
                     /locus_tag="IV356_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HAP9016138.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            7851..8606
                     /locus_tag="IV356_002495"
     CDS             7851..8606
                     /locus_tag="IV356_002495"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HAP9016139.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            8722..10020
                     /gene="eno"
                     /locus_tag="IV356_002496"
     CDS             8722..10020
                     /gene="eno"
                     /locus_tag="IV356_002496"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HAP9016140.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
BASE COUNT         3548 a         1869 c         2098 g         2611 t
ORIGIN      
        1 tcacaccttc ttttttgtat ataaaaatcc caagtaaata cataaaaaat aaaaaaattg
       61 aaacttttag cgcaccttgt acgtcatatt aagtgaggca gaaaggagtg gagaatgatt
      121 tttactggat ataagaaaaa acggcagatc gaaaaatacc gtcacctgct gaatggactc
      181 atcgaaactg attatcaaaa aatgttccgt atcacgatga attacgtaca tgataaagaa
      241 gaggccttag atgtgatgca agatagtttt cataaagccc tgaactattt tgaaaaagaa
      301 aaagagatcg agcattttag tgcatggttt tatcggatat tgatccgcac ggcattagat
      361 agttggcgca gacaaaaaag gacgcctgtg gacttatttg aaattcaaga tatcccccaa
      421 cagttacctt tagaaacttc cgttgcagag ctccatatga ttttagataa aatagacagt
      481 ccggaaaaag agattctgat cctctacttt tttgaaggat ttcgtttgaa agaaattgcg
      541 actatcttgg atatgaatga aaacacagtt aaaacgaaaa tgtaccgctc attgaatgct
      601 ttacgtcaaa tcctagaatg aaggagagaa gagtgccatg tattcccaaa aagaaaattt
      661 aaaaaaacta aagaaaactt ataaagaaca agcaattccc aaagggctta aagaggagat
      721 ccgccagcgt tttattatcg aagagcaatc atttataaaa gcaaagcgga gaaagagacg
      781 tctccaaggg ttcggagtat ctttggctat cgtaatgatt acaacaagta gccttctttt
      841 taatagtcaa gttcgaagct ttgcagaaga tttacccatc ttaggatcag tcattgaatt
      901 gatcttaggc gaacgcttta ctgatcgatc tgaaaaaatc gatattcagg taccgaagat
      961 caatacacaa aatgagaaag aaaataaaac aattcatgga ttaaatcaaa aatactttcg
     1021 cgaaggacaa gcagattttg aaaaagctga aaaagaatat ggaaattttg aaacggatca
     1081 ttaccaagtt ttgggagatt atcagaaaat cgtagacgat aaccggtttc tcgtgattga
     1141 aaggcagatc acccaaacag cagcagatag ccatgttgaa aaaagatacg acacaatcga
     1201 caagaaaaac agtgtccagc tctcacttcc acttttattc aaagatgaca cctatctatc
     1261 tgttttgaca aaagaagtca aacggcagat ggccgaacaa gtcaaggaag atccatctaa
     1321 gtactattgg actgagcaag atattcaaga agggacgata gaaaaaccaa cacttgttac
     1381 gcctacacga agtttttatt tgaacaaaga gcatcaatta gttttgactt tttctcaata
     1441 cgaaattgct cctggttata tgggtacacc agaatttgtc attcctaagt ccgtgacaaa
     1501 aacgattttg gcatcggaag attatttgga tcattagacg agaagtagtt gcgactagca
     1561 gtttcaattt tcaagtaagt acaagtaaat aataagaaga gaaaaagaga aagaagagat
     1621 atagtgaaaa gaaattattt agttatcagt attattgctt tatccgtgct tttgtttttc
     1681 gaaattactt cggtggcctc cttgatcacc gaagtaaaag gacaaacaca ctcttcggag
     1741 cattcgtcac aatctttcaa acaatcagaa caatcaacca ttaaaagcca atcaactgaa
     1801 acagctaacg tcaaagaagc cattcaagaa tcagcggaaa aggtacaaag tcagtcatca
     1861 caatcaacac aagacagtac aaaaacgagc cgagatccgg ctgtcaaaag cgtcgcaatc
     1921 agctttgatg atggaccagg agcgaccaca acaccgcagc ttctgcgaat cttaaaagaa
     1981 aaaaacgtgc atgccacttt tttcgtctta ggagaaaata cggcgcagca tcctgaaatc
     2041 gtgaagcaga cagctgaagc agggcacgag attggcaatc acacatacga tcatcagaat
     2101 ctggccactc tttctgccca gtcgatgacg gaggaagtga cgaaagcaga cactgagatc
     2161 aaaaaagtca ctggcaaaac ccccactttt gttcgtccgc cctatggttc tgtcacgaat
     2221 gtaggagcaa cgatcatcca gcgaccgatc atcgaatggt ctgttgattc agaagattgg
     2281 aagacaagaa atcctgattt gattttgcag aagatccaag caacagtata cgatggggca
     2341 attattttat tccatgatat ctatcctgaa acgattcgtg ccgttcctca agtgatcgat
     2401 tatctgaaag agcaagggta tcgcatcacg acagttgggg atttattagg gcatccaacg
     2461 gctgtcgaga actattatgg cagaaacgat catcggccag ttcagtaagt gagacaagta
     2521 tctttaataa ataacacatt ttaataagta gttgaacaca taactacctt acttgcaaag
     2581 gcttaacaat atctatacag gtacaacaaa aaactgtcca ccaattttct ttggcggaca
     2641 gttttcactt aaaaataaag aagcaactat tcgtaaatta tgctaaaata gcagtagaac
     2701 gcgtcctgag ggaatcgaac ccccgtctca agaaccggaa tcttacgtga tatccactac
     2761 actaaggacg caagcactgg gataattgta actaaacaga taaaaaatta caaggggatt
     2821 ggacaaaaaa atgaaatttg agcaaaattt ttcacaaaaa cagcagcaga cacagaaact
     2881 agccatgacg caacagttgc aacagtccat ccaagtttta caatataaca gtgaggagct
     2941 gttggcattc gttgagaatc aagcaatgga aaatccattg gtggaagttg ttgagccgga
     3001 atggcagcca gattacataa aagcttcttc atcttcttat gaaggagaag agacaaatta
     3061 cctaaatcag attcctgata caaaagggtc tttatttgat tcattgatcg aacaagtcca
     3121 tttgaattac cgagatactt ttttgaggaa aatcgttctt tatcttgtag aatacatcga
     3181 tttgaacgga tttttgacga ttagtttaga agaagccgga aaagagattg gagctacgcc
     3241 tatccaaatg ctcgatgcgt tgactctgat tcagcaatta gaaccagctg gagtaggtgc
     3301 acgtagtttg caagaatgtc tcatgcttca aacagaacga gatgattatg cgccggaatt
     3361 agcttatatc gtgttggaag aatgttttga ggaactggtg gagcgaaaat ggaaagaaat
     3421 cgcacaacgt ttttctgttg atctacatgc tgttcagcag atattcgact atttacaaac
     3481 gttgagtcca agccctggcc ggattttcga ccgtagcagc gaattgtaca ttattcctga
     3541 tgtccgggta ttagtggacg acgataaaaa tgtacaagtt atctcaaacc gaaaaaatca
     3601 gccaaatata cgctttcaag agagttactt caaacaaatg tcacaacaag cagataaaga
     3661 aactgaaaat tatttaaaag aacggaaaca ggaattcgaa tggttgaaga aaacgatcct
     3721 acaacgtggg gatacaattt tgcgggttgc tcaagtcatt gtttcccggc aaaaagcttt
     3781 ctttatcgac aaggaacgtc caatcaagcc tcttacgtta aaggaagttg caactgagat
     3841 agatgtgcat gaatccacgg tcagtcgtgc agtcaacggg aaatatttgg aaacagactt
     3901 cggtgtattt gaattaaaaa aatttttcac tacacgaatt cctacgaata gtacagaaca
     3961 gacagaagac ctttcagcag atacagcgaa gaaaaagctg caggaattag tcgatcaaga
     4021 agacaaaaac aagccgttgt ctgaccagaa attggttgaa ttgctgaaaa aagatgagat
     4081 agcgatctca agacgaacag tagcaaaata tcgtgattta ttaggaatcc cgagttcatc
     4141 aaaaagaaaa cgttatgata actaatcagt caaaagacta gaaaaagtat ttcacttttt
     4201 ctagtctttt tagttgaaaa acgagagcaa aactgttaga cttacagtcg tgaggttgag
     4261 atttcccttt attgatgtga aattcgaata gttaatttct ttttttatcg tatatgggtc
     4321 gttttaagtc tacattggac gtaaagtgtc caactaagga gatcgctatg ctggatgaaa
     4381 taaaaatgat tgaatctgtt gcaccagata ttatcgaagt gttgcaagaa cgctataaaa
     4441 ttttacgaaa tatctattgg atgcagccga ttggacgtcg aagtttatcg gaaagtatgg
     4501 ggatcacaga acgagtattg cgaacagaaa cagatctttt gaaaaatctg aatttgatcg
     4561 acacctcaaa aagcggtatg acgctgacaa ctaagggcga agaagtttat caaagccttg
     4621 aaaacttcat ggatcagctt ttaggtacgc atcaaaccga acaacagttg gcagaatatt
     4681 ttggtaacca acgctgtatc gttgtttcag gaaacagcga agagcagacc aaagtggctg
     4741 atgcattcgg cgaagcgctg agcgaagccc tagaccgact acttccagaa ggcgagaata
     4801 tcatcgctgt gatgggagga actactatgg ctgtggtagc cgaacaattg tctaatctgg
     4861 aaaataagaa acggcataac ctgtttgtcc ctgcaagagg cgggattggt gaagcgataa
     4921 ctgtacaggc aaattctgtc agtgcaagaa tggctgctaa agcaaacggt aaccaccgtg
     4981 cactttatgt tccggaacaa ttaagtctgg caacttacaa ttctttactc aatgagccat
     5041 ctatccaaga agtcttaaac ttgattagtg aagcgaattg tgttattcat agtattgggc
     5101 gtgcattaca catggcagca cgtcgtaaga tgactgaaaa agaattagtc atgctgaaac
     5161 aagcaaatgc tgttgcggaa tcttttggct actttttcaa tgaaaaaggt gaagtcgttt
     5221 ataaggtccc tagaatcggc atagaattgc aagatttgga aaaagtcccg atcatcatgg
     5281 caatcgcggg cggaaaatca aaagctaaag caattcgagc ttatatgaaa aatgcaccaa
     5341 aacaaacgtg gctcatcact gatgaagctg ctgcaaatga gattttaaaa ggggtaaccc
     5401 tttaaaataa atattttttt gattttcata aggaggaaat cttaaatgac agttaaagta
     5461 ggtattaatg gttttggacg tattggacgt ctagcattcc gtcgtatcca agatgtagat
     5521 ggaatcgaag tagtagcaat caacgacttg acagatgcta aaatgttggc acacttgtta
     5581 aaatacgaca caactcaagg acgtttcaac ggaacagttg aagttcatga aggttcattc
     5641 aacgtaaacg gaaaagaagt taaagtatta gctaaccgca acccagaaga attaccatgg
     5701 ggcgaactag gcgtagatat cgttctagaa tgtactggtt tcttcacttc taaatcagca
     5761 gctgaaaaac atttaacagc tggtgctaaa cgcgttgtta tctctgctcc tggcggaaac
     5821 gatgttccaa caatcgttta taacacaaac cacgaaacat taactggtaa agaaacagtt
     5881 atctcaggtg cttcatgtac tactaactgt ttagctccta tggctaaaac attgaacgac
     5941 aaatttggtg ttgttgaagg attaatgaca actatccacg cttacacagg tgaccaaatg
     6001 actctagacg gacctcatcc taaaggtgac ttccgccgtg cacgcgctgc tgctgcaaac
     6061 atcgttccta actcaacagg tgctgctaaa gctatcggtt tagtaattcc tgaattgaac
     6121 ggtaaattag acggagctgc tcaacgtgtt cctgtaccaa caggttcatt aacagaatta
     6181 gtaacagttc ttgaaaaaga agtaactgtt gacgaaatca atgcagcaat gaaagaagct
     6241 tcaaacgaat cttacggata caacacagac gaaatcgttt cttcagatat cgttggtatg
     6301 acttacggtt cattatttga tgctacacaa actaaagtaa tgacagttgg cgacaaacaa
     6361 ttagttaaaa ctgttgcttg gtacgacaac gaaatgtcat acactgcaca attagtacgt
     6421 actttagaat acttcgctaa cttataagat agacaaacgt acaagtgtaa attatagaca
     6481 tgtacattta aaagcgggga agcaatcgcg cttcttccgc tttttttgat aataagttta
     6541 ttcaggagga aataaaatgg ctaagaaaac agtgaaagat atcgatttaa aagacaaaaa
     6601 agttcttgtc cgtgttgact tcaacgttcc tttgaaagac ggcgtgatca ctgacgacac
     6661 tcgtatcaaa gcagcattgc caacaatcaa ctacgttcta gaacaaggcg gaaaagcaat
     6721 ccttttctct caccttggac gtgtaaaaac agaagaagat aaagaaggaa aatctttagc
     6781 tccagttgca aaacgtctag gcgaattatt aggtaaagaa gtaacattcg tacctgaaac
     6841 tcgcggagaa caattagaag aagcaatccg caacatgaat gacggcgacg ttgtcgtatt
     6901 cgaaaataca cgatttgaag atattgacgg taaaaaagaa agcaaaaatg atacagaact
     6961 aggtaaatac tgggcttcat taggcgatgt atttgttaac gatgctttcg gtacagctca
     7021 ccgtgcacat gcttctaacg taggtatcgc ttcaactggt atcccaacag ttgctggatt
     7081 cttgatggaa aaagaaatca agttcatcgg tgaagcagta gaagaaccaa aacgaccaat
     7141 gattgcaatc cttggtggcg caaaagtttc tgataaaatc ggcgtaatcg aaaacttgat
     7201 tcctaaagca gataaaatct tgatcggtgg cggaatgact tacacattct acgaagcaaa
     7261 aggaatcaag atcggtaact ctctagtaga agctgataaa gtggaactag caaaagaatt
     7321 aatcgaaaaa gcaggcgaca aacttgtctt gccaatcgac aatgtctgtg caccagaatt
     7381 ttcaaatgat gttgaaacac aagtaatcga aggagacatt cctgatggtt tgatggcttt
     7441 agacatcggc ccagcatcag taaaattatt tgctgataca ttacaaggtg caaaaacagt
     7501 tgtttggaac ggacctatgg gtgtatttga aatgagtaac tttgctaaag gtacaatcgg
     7561 tgtttgtgaa gcaatcgcta acttagaagg cgcaacaaca atcatcggtg gcggagactc
     7621 agctgcagca gcagaacaat taggatttgc tgacaaattc acacacatct caacaggtgg
     7681 tggcgcaagc ttggaattgc ttgaaggtaa agaattacca ggactagcag caatcaacga
     7741 taaataaacg accaagtttg ctcaattctg acgagtaatc gatcaaaagg tgaagggagt
     7801 tttcatgact ccctagccat ttttcaataa attaaggagt gtgttcctca atgcgtaaac
     7861 ctattatcgc aggtaactgg aaaatgaaca aaactgcatc agaagcaaaa gaatttgctg
     7921 aagcagtaaa aaacaaaatc ccttcaaatg acaaagttga ttcagtcatc ggatctcctg
     7981 cattattctt acaagaatta atgacatcag ctgaaggtac agaactaaaa atctcagcac
     8041 aaaactgcta ctgggaaaac tcaggtgcgt tcactggtga aacttcacca gcagctcttg
     8101 ctgatctagg tgttcattat gtgatcatcg gacattcaga acgtcgtgaa tatttccatg
     8161 aaacagacga agacatcaat aaaaaagcaa aagctatctt tgcaaatggt atgacaccaa
     8221 tcctatgctg cggcgaatct ttagaaacct atgaagcagg caaaactgct gaatggatcg
     8281 aaggacaaat tacagctggt ttagctgatc tttcagctga acaagtgtca aacatggtta
     8341 ttgcttatga accaatctgg gcaatcggta ctggtaaatc agctgacgca caaatcgctg
     8401 acgaaatttg tggagttgta cgtcaaacag ttgaaaaact ttatggaaaa gaagtatcag
     8461 aagcagttcg tatccaatac ggcggttctg taaaaccaga aaatattgct gaatacatgg
     8521 caaaagaaaa tgttgacggt gctttagtcg gtggcgcaag cttgcaagca gattcatttt
     8581 tgtcattgtt agacgctgta aaataattgt tgaaaatttg cgaaaaatgc aagaaatgtt
     8641 tgcactaatg agcaaaatta actaaaatcg tatatgaggg aaatccctta ggaaaaaaca
     8701 aactcaaagg agagacaaaa catgtcaatt attactgatg tttacgctcg cgagatctta
     8761 gactcacgtg gtaacccaac aatcgaagta gaagtataca cagaaagcgg agcttttggc
     8821 cgcggaatgg ttccttcagg tgcttcaact ggtgaatacg aagcagttga attacgtgac
     8881 ggagacaaag ctcgttatgg cggtaaaggt gtaactaaag ctgtcgacaa cgtaaacaac
     8941 atcattgctg aagcaatcat tggctacgat gttcgtgacc aaatggctat cgacaaagct
     9001 atgatcgctt tagacggaac tcctaacaaa ggtaaattag gtgcgaacgc tattttaggt
     9061 gtttctatcg ctgttgcacg tgcagctgct gactacctag aagtaccttt ataccactac
     9121 ctaggcggat tcaacacaaa agtattgcca acaccaatga tgaacatcat caacggcgga
     9181 tcacatgctg ataactcaat cgacttccaa gaattcatga tcatgcctgt tggcgctcca
     9241 acattcaaag aagctctacg tatgggtgct gaagtattcc acgcattagc ttcaatcttg
     9301 aaagctcgcg gattagcaac ttctgttggt gacgaaggtg gatttgctcc aaaccttggt
     9361 tcaaacgaag aaggttttga agtaatcatc gaagcaatcg aaaaagctgg ctatgtacct
     9421 ggtaaagacg ttgttcttgc tatggatgct gcttcttcag aattctacga caaagaaaaa
     9481 ggtgtttacg tactagctga ctcaggcgaa ggcgaaaaaa caactgacga aatgatcaaa
     9541 ttctacgaag aattagtttc taaatatcca atcatctcaa tcgaagatgg attagacgaa
     9601 aacgactggg acggattcaa gaaattaact gacgtattag gcgacaaagt tcaattagtt
     9661 ggtgacgact tgttcgtaac aaacactcaa aaattatctg aaggtatcga aaaaggaatt
     9721 gctaactcaa tccttatcaa agtgaaccaa atcggtacat taacagaaac tttcgaagct
     9781 atcgaaatgg ctaaagaagc tggctacaca gcagttgtat ctcaccgttc tggtgaaaca
     9841 gaagattcaa caatctctga tatcgctgtt gcaacaaatg ctggccaaat caaaactggt
     9901 tctctatcac gtactgaccg tattgctaaa tacaaccaat tactacgtat cgaagaccaa
     9961 cttggtgaag ttgcagaata caaaggtttg aaatctttct acaacttaaa aaacaaataa
    10021 ttcttttcta atgaagatac atgatcgact attgaaagat agtcgagtat gatcacttag
    10081 ttaagtaatc gaactctcta cttgctgaaa tatcagcagg tagaga
//
LOCUS       DACDLM010000090        10086 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.092, whole genome shotgun sequence.
ACCESSION   DACDLM010000090 DACDLM010000000
VERSION     DACDLM010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10086
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.092"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..722)
                     /locus_tag="IV356_002497"
     CDS             complement(<1..722)
                     /locus_tag="IV356_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAP9016141.1"
                     /translation="MTYKNIVFDLDDTLYDHQLPFKRSVEKCFPTIDIQQIDNIYKRF
                     RCWSDVAFPKYTKKLISIEQLRIFRCQKTMEEFGIDSISRTEALDFQADYEYELDQIT
                     MIPEIHQLLLALHKNRIPIGILTNGPVDLQSRKLQNIGAYQYFEKQNIIISQSTHGGA
                     AENSYEGNVKNLQSYQNVQLSKRAIEILKEEIELNHQHIRFNPDYKDNGWIFTSKSRH
                     KPGMATVFLTNFIRCRTSFRML"
     gene            complement(727..1494)
                     /locus_tag="IV356_002498"
     CDS             complement(727..1494)
                     /locus_tag="IV356_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP9016142.1"
                     /translation="MNKKRRLEKILDMLKIDGTITIKEIIDELDISDMTARRDLDALE
                     ADGLLTRTHGGAQLLSSKKPLEKTHIEKKSLNTKEKIDIAKKACSLIKDGDTIFIGPG
                     TTLEQLALELKGRKGYKIRVITNSLPVFLILNDSETIDLLLLGGEYREITGAFVGSMA
                     STNLKAIRFAKAFVSANAVTHNSIATYSDKEGVIQQLALNNAVEKFLLVDSTKFDRYD
                     FFNFYNLDQLDTIITDNQISPQHLEEFSQYTTILKAD"
     gene            1983..2408
                     /gene="lacA"
                     /locus_tag="IV356_002499"
     CDS             1983..2408
                     /gene="lacA"
                     /locus_tag="IV356_002499"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HAP9016143.1"
                     /translation="MAIVVGADLKGTRLKDVVKNFLVEEGFEVIDVTKDGQDFVDVTL
                     AVASEVNKDEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     VGAEIVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            2425..2940
                     /gene="lacB"
                     /locus_tag="IV356_002500"
     CDS             2425..2940
                     /gene="lacB"
                     /locus_tag="IV356_002500"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HAP9016144.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGHEVLDFGTYDHARTHYPI
                     YGKKVGEAVVSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSAIYAKEELNAN
                     VIGFGGKITGGLLMNDIIEAFIEAEYKPTEENKKLIAKIEHVETHNAHQADEDFFTEF
                     LERWDRGDYHD"
     gene            2951..3883
                     /gene="lacC"
                     /locus_tag="IV356_002501"
     CDS             2951..3883
                     /gene="lacC"
                     /locus_tag="IV356_002501"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HAP9016145.1"
                     /translation="MILTVTLNPSVDISYPLETLKIDTVNRVKDVSKTAGGKGLNVTR
                     VLYESGDKVTATGFLGGKIGEFIESELEQSPVSPAFYKISGNTRNCIAILHEGNQTEI
                     LEQGPTISHEEAEGFLDHYSNLIKQSEVVTISGSLPSGLPNDYYEKLIQLASDEGVAV
                     VLDCSGAPLETVLKSSAKPTAIKPNNEELSQLLGKEVTKDIEELKDVLKESLFSGIEW
                     IVVSLGRNGAFAKHGDVFYKVDIPDIPVVNPVGSGDSTVAGIASALNSKKSDADLLKH
                     AMTLGMLNAQETMTGHVNMTNYETLNSQIGVKEV"
     gene            3886..4866
                     /gene="lacD"
                     /locus_tag="IV356_002502"
     CDS             3886..4866
                     /gene="lacD"
                     /locus_tag="IV356_002502"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAP9016146.1"
                     /translation="MVLTEQKRKSLEKISDKNGVISALAFDQRGALKRLMAQYQDTEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDKEAGLLLAYEKTGYDTSSTK
                     RLPDCLDVWSAKRIKEQGADAVKFLLYYDVDSSDELNQQKQAYIERVGSECVAEDIPF
                     FLEILAYDEEISDAGSVEYAKVKPRKVIEAMKVFSDPRFNIDVLKVEVPVNVKYVEGF
                     ADGEVVYSKAEAADFFKAQEEATNLPYIYLSAGVSAKLFQETLQFAHDSGAKFNGVLC
                     GRATWAGSVEPYIKEGEKAAREWLRTTGFENIDELNKVLVKTASPWTDKV"
     gene            4894..5211
                     /locus_tag="IV356_002503"
     CDS             4894..5211
                     /locus_tag="IV356_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011669100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAP9016147.1"
                     /translation="MNREEMTLLGFEIVAYAGDARSKLLEALKAAENGDFAKADSLVV
                     EAGSCIAEAHNSQTAMLAREASGEELPYSVTMMHGQDHLMTTVLLKDVIHHLIELYKR
                     GAK"
     gene            5211..6917
                     /locus_tag="IV356_002504"
     CDS             5211..6917
                     /locus_tag="IV356_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP9016148.1"
                     /translation="MHKLIELIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIETFLMTPYSYSMGILAFFVGGTTAKALTDSMNRDLPATNQ
                     INFLSTMLASMVGFLLMAAEPAKEGGFLTAFTGTKGLLTAFIAAFVTVNVYKVCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTVAVVLLYGFELIVKGTLGVTVAESIGTLLAPLFS
                     AADGYLGITLIFGAYAFFWFVGIHGPSIVEPAIAAITYANIDANLHLIQAGQHADKVI
                     TSGTQMFIVTMGGTGATLIVPFLFMWICKSERNRAIGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFVPFIFAPIVNVWIFKFFVDTLNMNSFSANLPWVTPGPLGIVLGTNFQVLSF
                     ILAGLLVVVDTIIYYPFVKVYDEQILEEERSGKTNDALKEKVAANFNTAKADAVLGKA
                     GVAKEDVAANNNITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGSYGAHR
                     EMLPEFDLVILAPQVASNFDDMKAETDKLGIKLAKTEGAQYIKLTRDGQGALAFVQQQ
                     FD"
     gene            7059..8465
                     /gene="lacG"
                     /locus_tag="IV356_002505"
     CDS             7059..8465
                     /gene="lacG"
                     /locus_tag="IV356_002505"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HAP9016149.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYHKYPVDLELAEKYGVNGIRISIAWSRIFPTGYGEVNEKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEVLHSDGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPYDPENPADVRAAELEDIIHNKFILDATYLGHYSDKTMEGVNHILAENGGELDL
                     RDEDFQALEAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     IAPDYVPRTDWDWIIYPEGLYDQIMRLKNDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFDTQERY
                     PKKSAHWYKKVAETQVIE"
     gene            8488..8761
                     /locus_tag="IV356_002506"
                     /pseudo
     CDS             8488..8761
                     /locus_tag="IV356_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209209.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
     gene            8782..9681
                     /locus_tag="IV356_002507"
     CDS             8782..9681
                     /locus_tag="IV356_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HAP9016150.1"
                     /translation="MTIELKNEYLTVQFKTLGGQLTSIKDEDGIEYLWQADPNYWNGQ
                     APILFPICGSLRNDWAIYRPQERPFFTGLIRRHGFVRKEEFILEEVNDNSVTFSIKPN
                     AEMLDNYLYQFELRVVYTLNGKSIRTEFQVTNLEMEKTMPYFIGAHPAFNSSLVEGEN
                     YEDYYIEFSEVESCSIPKSFPETGLLDLQDRTPFLENQKILDLDYSLFSHDAITLDQL
                     KSRSVTLRSRKSGKGLRVDFDDFPNLILWSTTNKSPFIALEPWSGLSTSLEEGNFLED
                     KRQVTKISPQETSRKIYDITILN"
BASE COUNT         3181 a         1700 c         2018 g         3187 t
ORIGIN      
        1 aatagcatac ggaaagaagt tctgcacctt ataaaatttg tcaaaaaaac tgttgccatt
       61 ccaggtttat gacgactttt ggaagtaaaa atccatccat tatctttata atcaggattg
      121 aatcttatat gttggtgatt taactcaatt tcctctttaa gaatttctat agccctttta
      181 gataattgga cattttggta actttgtaag ttttttacat taccttcata gctattttct
      241 gcagctcctc cgtgagtgga ctgactaatg atgatatttt gcttttcaaa atattgatag
      301 gcaccaatat tttggagttt tcgactctgt aagtcaacag ggccattagt tagaatacct
      361 attgggatgc ggtttttatg tagagccagc agtagttgat gtatctcagg aatcatcgta
      421 atctgatcga gttcatattc atagtcagct tggaagtcta gagcttctgt cctagaaata
      481 ctatcgatgc caaattcttc catagtcttc tgacagcgaa aaattctaag ctgctcaata
      541 ctgatgagtt ttttcgtgta tttaggaaaa gcaacatcag accaacatct gaaacgtttg
      601 taaatgttat ctatttgttg gatatcaatc gttggaaaac atttctcaac gctacgttta
      661 aaggggagtt gatggtcata aagagtgtca tcaaggtcaa aaacaatatt tttataagtc
      721 ataattctag tccgctttta aaatagtagt gtactggcta aattcctcta agtgttgagg
      781 gctaatctgg ttatctgtaa tgatggtatc gagttgatct agattataga agttaaagaa
      841 atcgtatcga tcgaatttag tactgtctac taataagaat ttttctacag cattgtttag
      901 ggcaagttgt tgaatcacac cttccttgtc actatatgta gcaatagaat tatgggtaac
      961 agcatttgca ctaacaaaag ctttggcaaa tctaattgct tttaaatttg tcgaagccat
     1021 tgaacctaca aaagctccag ttatttctct atattcaccg ccaagaagca ataaatcaat
     1081 ggtttcgcta tcatttagaa tcaagaacac agggagacta tttgtaatga cacgaatttt
     1141 ataaccttta cgacctttca attctaatgc cagttgttca agtgtagttc cgggtccaat
     1201 aaaaatagta tcgccatctt tgattaaaga gcaggctttt ttagcaatgt caattttttc
     1261 ttttgtattt agacttttct tctcgatatg tgtcttttca agtggctttt tagaggaaag
     1321 taattgtgca ccaccatgag tacgtgttaa aagtccatca gcttctagag catcaaggtc
     1381 tctacgggct gtcatatcgg aaatatctag ttcatctatt atttctttta tggttatggt
     1441 cccatcaatc tttaacatat ctaaaatttt ttctaatcgt cgttttttgt tcatatgaag
     1501 acccttcttt cataaagtaa tttttttcca aagataattc tcttttaatt gtatcataaa
     1561 agacaatatt ttcaaggtaa aacaaacaat ttcaaacaaa aacaaatgtt agatgatgaa
     1621 ataagaacag tggattgacg tatattagct taggtcagat tttgtataag acgaaaataa
     1681 agtaggacct cttaatcagt aagttataga aagtaaaaga cttttgtaat acttgaatag
     1741 atatttcacg tccattttgt gatggattaa atgaacaaaa atgaacaata atttaacggt
     1801 gttatctatt ttttaagaaa acaaataaaa aaaacaaaaa ataaacaaaa aagtgttgct
     1861 tttcgtttga atgattgata ttatataaac aaagaaatga tgaaaacgtt ttttcgaaca
     1921 ttttgcaaaa tgttttctac ttctacgtag catttctttc taaaatttag gaggtggtca
     1981 aaatggctat tgttgttggt gcagatctca aaggtacgag attaaaagat gttgtgaaaa
     2041 attttcttgt agaagaaggt tttgaggtaa ttgatgtgac taaggacgga caagattttg
     2101 ttgatgttac cttggcagtt gcctctgaag taaataaaga tgagcaaaac ttaggtattg
     2161 taattgatgc ttatggagct ggtccattca tggtagcaac taaaattaaa ggtatggttg
     2221 cagcagaagt ttcagatgaa cgctcagctt atatgacacg tggacataac aattcacgaa
     2281 tgattacggt tggcgctgaa atcgtcggtg atgagcttgc taaaaacatc gctaaaggtt
     2341 tcgtcaatgg taaatatgat ggcggacgtc atcaaatccg agtagatatg cttaacaaaa
     2401 tgtgttaaga aaaggagtta aggaatgaga atcgcaattg gatgtgacca cattgtcaca
     2461 gatgaaaaaa tggcagtatc agaattcttg aaatcaaaag gacatgaggt ccttgatttc
     2521 gggacatatg accacgcacg tactcactac cctatctatg gtaaaaaagt cggtgaagca
     2581 gtagtaagtg gtcaagcaga cttgggagta tgtatctgtg gtacaggtgt cggcattaac
     2641 aatgcagtca ataaagttcc aggtgttcgc tcagcgttgg ttcgtgatat gacatcagct
     2701 atatatgcaa aagaagagtt aaatgcgaat gttatcggtt tcggtggaaa gattactggt
     2761 ggtcttctta tgaatgacat cattgaagct ttcattgaag ctgagtacaa accaacagaa
     2821 gaaaataaaa aattgattgc aaaaatcgaa cacgttgaaa cacataatgc acatcaagca
     2881 gatgaagatt tctttacaga attccttgaa agatgggacc gtggtgacta ccacgattaa
     2941 ggtataacaa atgattctga cagtcacact aaatccttca gtagacatct cttatcctct
     3001 agaaacattg aaaattgata cagtgaatag ggtgaaagat gttagtaaga cagctggtgg
     3061 aaaaggctta aatgttacta gagtcttgta tgaatctggt gataaagtta ctgctacagg
     3121 tttcttaggt ggtaaaattg gtgaatttat tgaaagcgaa ttagaacaat ctcctgttag
     3181 tccagctttt tataaaatct caggaaacac tagaaactgt attgctatct tacacgaggg
     3241 taaccaaaca gaaattttgg aacaaggacc aacaatttct catgaagaag cagaaggctt
     3301 tcttgaccac tatagcaatc ttattaaaca atcagaagtt gtgacaattt caggaagttt
     3361 accttcagga cttcccaacg attattatga aaaacttatc caacttgctt cggatgaagg
     3421 agtagcagtc gttttggatt gttcaggtgc acctcttgaa acagttctaa aatcgtcggc
     3481 taaacctact gccatcaaac ctaataatga ggaactttca cagttgcttg gaaaagaagt
     3541 aacaaaagat attgaagaac tcaaagacgt tcttaaagag tcacttttta gtggtatcga
     3601 atggatagtg gtctcattag gtcgaaacgg tgcctttgca aaacatggtg atgttttcta
     3661 taaggtagat attcctgata tcccagttgt taatccagtc ggatcagggg actcaacggt
     3721 agctggtatt gcatcagctt taaatagtaa aaaaagtgac gctgacttat taaaacatgc
     3781 gatgacattg ggtatgttaa atgctcaaga aacaatgaca gggcatgtga atatgactaa
     3841 ttacgaaaca ctaaactcac aaattggagt aaaagaggta taaaaatggt acttacagaa
     3901 cagaaacgca aatctttgga aaaaatttca gataaaaacg gtgttatctc agctttggca
     3961 tttgaccaac gtggtgcttt gaaacgtttg atggcacagt atcaagatac agaaccaact
     4021 gtagctcaaa tggaagaact aaaggttttg gttgctgatg aacttacaaa atacgcttct
     4081 tcaatgttgc ttgaccctga atatggactt ccagcaacaa aagcattgga taaagaagca
     4141 ggtcttcttc ttgcctatga aaaaacaggt tatgatacat caagtacaaa acgtttgcct
     4201 gactgcttgg atgtttggtc tgcaaaacgt atcaaagagc aaggcgctga tgccgttaag
     4261 ttcttgcttt actatgatgt agacagctca gatgaactta accaacaaaa acaagcttat
     4321 attgaacgtg ttggttctga atgtgtcgct gaagatattc ctttcttctt ggaaatcctt
     4381 gcttatgatg aagaaatctc agatgcaggt tctgttgaat atgcaaaagt gaaacctcgc
     4441 aaagtcattg aagcgatgaa agttttctct gatccacgct ttaacattga tgttcttaaa
     4501 gtagaagtac cagttaacgt taaatatgtc gaaggttttg ctgatggtga agtggtttac
     4561 agtaaagctg aagctgctga cttctttaaa gcacaagaag aagcgactaa ccttccatac
     4621 atctacctaa gtgcaggtgt atctgctaaa ttgttccaag aaacattgca atttgctcac
     4681 gactcaggtg ccaagtttaa tggtgtgctt tgtggacgtg ctacttgggc aggatctgta
     4741 gaaccttaca tcaaagaagg tgaaaaagca gcacgtgaat ggttgcgtac tactggattc
     4801 gaaaatattg atgaacttaa caaagttctt gttaaaacag ctagtccatg gactgataaa
     4861 gtatagtaaa aacataaaac ggaggatatt gttatgaaca gagaagagat gactctctta
     4921 gggtttgaaa ttgttgctta tgctggagat gctcgctcta aacttttaga agcgcttaaa
     4981 gcggctgaaa atggtgattt cgctaaggca gatagtcttg tagtagaagc aggaagctgt
     5041 attgcagagg ctcacaattc tcagacagct atgttggctc gagaagcttc tggggaggaa
     5101 cttccataca gcgttaccat gatgcatggt caggaccact taatgactac tgtcttatta
     5161 aaagatgtga ttcatcacct catcgaactt tataaaagag gagcaaaata atgcataaac
     5221 tcattgaact tattgagaaa gggaaaccgt tctttgagaa aatctctcga aacatctatc
     5281 ttcgtgctat tcgtgatgga tttatcgctg gtatgccagt catccttttc tcatctatct
     5341 ttatccttat tgcctatgtc ccaaatgctt ggggattcca ctggtcaaaa gacattgaga
     5401 ccttcttgat gactccttat agctattcga tgggtatcct agcattcttt gttggtggta
     5461 ctaccgctaa agctttgacg gactcaatga accgtgacct acctgcgacc aatcagatta
     5521 acttcttatc tacgatgcta gcgtctatgg tagggttcct tttgatggca gctgagcctg
     5581 caaaagaagg aggcttcttg acagccttca cgggaacaaa aggtcttttg acagcattta
     5641 ttgcagcctt tgtgacagtt aatgtttaca aggtctgtgt gaaaaataat gttactattc
     5701 gtatgcctga agaggttcca ccaaatatct ctcaagtatt taaagacttg attccattca
     5761 ctgtagcggt tgttctcctt tatggatttg aactcattgt taagggaact cttggtgtaa
     5821 ccgttgcaga atcaatcggt acccttcttg ctcctctctt ctcagctgca gatggttacc
     5881 ttggaattac acttatcttt ggtgcttatg ccttcttctg gtttgttggt atccacggtc
     5941 cttcaattgt cgaaccagca atcgctgcta tcacttatgc caatatcgat gccaacttgc
     6001 atcttatcca agctggacaa catgcagata aagttatcac ttctggtact caaatgttta
     6061 ttgttaccat gggtggaaca ggagctacat tgattgttcc attcttgttc atgtggattt
     6121 gtaaatcaga acgtaaccgt gccatcggac gtgcctcagt tgttccaaca ttctttgggg
     6181 ttaatgagcc aatcttattt ggtgcaccaa tcgtattgaa tccgattttc tttgtaccgt
     6241 tcattttcgc tccgattgtc aacgtttgga tctttaaatt ctttgttgac acattgaaca
     6301 tgaactcatt ctctgccaac cttccatggg ttactcctgg tccgttggga attgtactcg
     6361 gtactaactt ccaagttcta tcatttatct tagccggact cttggtagtt gttgatacta
     6421 tcatttatta cccatttgtt aaggtatacg atgaacaaat tcttgaagaa gaacgttctg
     6481 gtaaaacaaa cgatgctctt aaagaaaaag tagctgcaaa cttcaatact gctaaagcag
     6541 atgccgttct tggaaaagca ggcgttgcta aagaagatgt agcagcaaac aataatatca
     6601 caaaagaaac taatgtcctt gttctttgtg caggtggagg tacaagtggc ttgcttgcca
     6661 atgccttgaa caaagcagca gcagaataca atgttccagt caaagcggca gcgggtagtt
     6721 acggtgctca ccgtgaaatg ttgccagagt ttgacttggt tatcttggct ccgcaggtcg
     6781 cttcaaactt cgatgatatg aaggctgaaa cggataaatt gggcattaaa cttgcaaaaa
     6841 ctgaaggagc tcaatatatc aaattgacac gtgatggaca aggtgctctt gcatttgttc
     6901 aacaacagtt tgattaataa atttgtaaaa gttatttgag acgagattat tctttcagtt
     6961 ccttataata ttgttaacca tatcattgca tttcatttcc ttggtttccg gaactcagaa
     7021 tatcgtctca aatgcttttt ttgaaaggat ttatagttat gactaaaaca cttcctaaag
     7081 attttatttt tggtggtgct acagctgctt atcaagcaga aggtgcgact cacacggatg
     7141 gtaaaggccc agttgcatgg gataagtatc ttgaagacaa ttattggtac acagcagagc
     7201 ctgcaagtga tttttaccat aaatatcctg ttgatttaga attagctgaa aaatatggcg
     7261 ttaatggtat tcgtatttca attgcctggt ctcgtatttt cccaactggc tatggcgaag
     7321 taaatgaaaa aggtgttgaa ttctaccata atctttttgc cgagtgccac aaacgtcatg
     7381 ttgagccatt cgtgactttg caccactttg acacaccaga agttcttcac tcagatggag
     7441 atttcttaaa ccgcgaaaat atagaacact ttgtagatta tgccgctttc tgttttgaag
     7501 agttcccaga agtaaactac tggacaactt tcaatgaaat tggcccaatt ggagatggtc
     7561 aatacttggt tggtaaattc cctccaggca ttcaatatga tcttgccaaa gtcttccaat
     7621 cacaccacaa tatgatggtt tctcatgcac gtgctgtgaa attgtataaa gataaaggtt
     7681 ataaaggcga aattggtgta gtacatgcgt tgccaaccaa atacccttat gatccagaaa
     7741 atccagcaga tgttcgtgcc gctgagttag aagatatcat ccataacaaa tttatcttgg
     7801 atgcaaccta ccttggacac tattcagata aaacgatgga aggggtcaac cacatcctag
     7861 ctgaaaatgg tggagaactt gatcttcgtg atgaagactt ccaagcactt gaagcagcta
     7921 aagatttgaa cgatttcctt ggtatcaact actacatgag tgattggatg caagcctttg
     7981 atggtgagac tgaaatcatt cacaatggta agggtgaaaa aggaagttct aagtaccaga
     8041 ttaaaggtgt tggtcgccga atcgcaccag attatgtgcc tagaacggat tgggactgga
     8101 ttatttatcc tgaaggcttg tatgaccaaa tcatgcgatt gaaaaatgat tatccaaact
     8161 acaagaagat ttacatcact gaaaacggtc ttggatacaa agatgagttt gtagataata
     8221 ccgtttatga tgatggtcgt attgattacg tgaagaaaca cttggaagtt ttatcagacg
     8281 caattgcgga tggtgcaaat gttaaaggtt acttcatctg gtcacttatg gatgtcttct
     8341 catggtcaaa cggatacgaa aaacgttatg gactattcta tgtagacttt gacacgcaag
     8401 aacgctatcc taagaaatca gctcattggt ataagaaagt agcagaaact caagtgatag
     8461 agtaatatta cttgaaaatg taaaaaattg ttatccgata ctttagaaaa agtacaacac
     8521 ttatttagac caggctttga aaaggtatat attgttagtt tcgaagattg tcctatgatt
     8581 cctgagcttg aagctaccct cgttgctaaa atgtggtaaa tggtatgttt taactggaaa
     8641 agagtggatt tgccattctg atttagagtt atcagcattt gaatgggaat ttttacaatc
     8701 actcgatgta gaaatacgtg agactattca cttcgaggta aattatttgc ctttccaata
     8761 ataaaaagaa aggaattagt tgtgactatc gaattaaaaa acgagtatct tactgttcag
     8821 tttaaaacac ttggtggtca actgacttcg attaaagacg aggatgggat agagtatctc
     8881 tggcaagctg atccaaatta ttggaatgga caggcgccta ttctatttcc tatctgtggt
     8941 agtttacgaa atgattgggc tatttataga cctcaagaaa gacctttttt tacaggtctt
     9001 attcgtagac atggttttgt tcgaaaagaa gaatttattc tggaagaagt caatgataat
     9061 agcgtgacct ttagtattaa accaaatgct gagatgcttg ataattacct atatcagttt
     9121 gaactgagag ttgtttatac cttgaatggt aaatcaatta gaaccgaatt tcaggtaacg
     9181 aacttggaaa tggaaaaaac aatgccttac tttattggag cccatccagc attcaatagt
     9241 tctttagtag aaggtgaaaa ctatgaggat tattatattg aatttagtga ggttgagtct
     9301 tgctcgatac caaagagttt tcctgagaca ggattattag atttgcaaga tcggacacct
     9361 tttttggaaa atcaaaaaat tctcgatttg gactactcac ttttttccca tgatgccatt
     9421 acacttgacc agctcaagtc tcgtagcgta acgcttcggt caaggaagtc tggtaaaggt
     9481 cttcgagtag attttgatga ttttccgaac ttgattctgt ggtctacaac taataaaagt
     9541 ccattcattg ctttggaacc ttggagtggt ctctccactt cacttgaaga aggtaatttc
     9601 ttagaagata aaagacaggt aacgaaaatt tcacctcaag aaacttctag aaaaatctat
     9661 gatattacta tccttaatta aaatttgtta ttatttgagt cttcaataag atttgaatac
     9721 tcttaccttg tgatgataga ttggtcttct ccgtgccagt cttacatcgc aaggttttta
     9781 agttttttgt gggtctatgt caactgtagt gggtgacgaa aagctaatat ctaaagacag
     9841 tctggtagta aaaaataaga ttatttacta cttcttgatt taaaataata gtggagccat
     9901 taatttgtgg caaatttaat ttaatatttt gcctcaaatt agccacactt tttatagaac
     9961 taagaggaaa aatgaaattt tcttcctatt aatatagttg tttgaaatct taaatatagc
    10021 gttttggaat ggcaacagtt tttttgacaa attttataag gtgcagaact tctttccgta
    10081 tgctat
//
LOCUS       DACDLM010000091         9966 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.093, whole genome shotgun sequence.
ACCESSION   DACDLM010000091 DACDLM010000000
VERSION     DACDLM010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9966
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.093"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            8..81
                     /locus_tag="IV356_002508"
     tRNA            8..81
                     /locus_tag="IV356_002508"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:42..44,aa:Pro,seq:tgg)
     gene            101..173
                     /locus_tag="IV356_002509"
     tRNA            101..173
                     /locus_tag="IV356_002509"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:134..136,aa:Ala,seq:tgc)
     gene            201..274
                     /locus_tag="IV356_002510"
     tRNA            201..274
                     /locus_tag="IV356_002510"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:235..237,aa:Met,seq:cat)
     gene            288..361
                     /locus_tag="IV356_002511"
     tRNA            288..361
                     /locus_tag="IV356_002511"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:322..324,aa:Ile,seq:cat)
     gene            385..474
                     /locus_tag="IV356_002512"
     tRNA            385..474
                     /locus_tag="IV356_002512"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:421..423,aa:Ser,seq:tga)
     gene            487..560
                     /locus_tag="IV356_002513"
     tRNA            487..560
                     /locus_tag="IV356_002513"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:521..523,aa:Met,seq:cat)
     gene            579..654
                     /locus_tag="IV356_002514"
     tRNA            579..654
                     /locus_tag="IV356_002514"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:612..614,aa:Asp,seq:gtc)
     gene            656..726
                     /locus_tag="IV356_002515"
     tRNA            656..726
                     /locus_tag="IV356_002515"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:688..690,aa:Gly,seq:tcc)
     gene            740..813
                     /locus_tag="IV356_002516"
     tRNA            740..813
                     /locus_tag="IV356_002516"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:774..776,aa:Ile,seq:gat)
     gene            838..925
                     /locus_tag="IV356_002517"
     tRNA            838..925
                     /locus_tag="IV356_002517"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:872..874,aa:Ser,seq:gct)
     gene            947..1018
                     /locus_tag="IV356_002518"
     tRNA            947..1018
                     /locus_tag="IV356_002518"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:980..982,aa:Glu,seq:ttc)
     gene            1041..1130
                     /locus_tag="IV356_002519"
     tRNA            1041..1130
                     /locus_tag="IV356_002519"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1077..1079,aa:Ser,seq:tga)
     gene            1143..1216
                     /locus_tag="IV356_002520"
     tRNA            1143..1216
                     /locus_tag="IV356_002520"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1177..1179,aa:Met,seq:cat)
     gene            1235..1307
                     /locus_tag="IV356_002521"
     tRNA            1235..1307
                     /locus_tag="IV356_002521"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1268..1270,aa:Asp,seq:gtc)
     gene            1311..1383
                     /locus_tag="IV356_002522"
     tRNA            1311..1383
                     /locus_tag="IV356_002522"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1344..1346,aa:Phe,seq:gaa)
     gene            1388..1458
                     /locus_tag="IV356_002523"
     tRNA            1388..1458
                     /locus_tag="IV356_002523"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1420..1422,aa:Gly,seq:tcc)
     gene            1471..1544
                     /locus_tag="IV356_002524"
     tRNA            1471..1544
                     /locus_tag="IV356_002524"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1505..1507,aa:Ile,seq:gat)
     gene            1556..1627
                     /locus_tag="IV356_002525"
     tRNA            1556..1627
                     /locus_tag="IV356_002525"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1589..1591,aa:Glu,seq:ttc)
     gene            1893..3086
                     /locus_tag="IV356_002526"
     CDS             1893..3086
                     /locus_tag="IV356_002526"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HAP9016151.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            3216..4688
                     /locus_tag="IV356_002527"
     CDS             3216..4688
                     /locus_tag="IV356_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP9016152.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            4771..5559
                     /locus_tag="IV356_002528"
     CDS             4771..5559
                     /locus_tag="IV356_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HAP9016153.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(5626..6294)
                     /locus_tag="IV356_002529"
     CDS             complement(5626..6294)
                     /locus_tag="IV356_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAP9016154.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            6409..8121
                     /locus_tag="IV356_002530"
     CDS             6409..8121
                     /locus_tag="IV356_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9016155.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            8124..9896
                     /locus_tag="IV356_002531"
     CDS             8124..9896
                     /locus_tag="IV356_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9016156.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
BASE COUNT         2901 a         1781 c         2279 g         3005 t
ORIGIN      
        1 aattaaacgg gaagtagctc agcttggtag agcacttggt ttgggaccaa ggggtcgcag
       61 gttcgaatcc tgtcttcccg ataattataa atttaaacac ggggccttag ctcagctggg
      121 agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct ccatttcatt
      181 taaataatga atatcttttt cgcggtgtag ctcagctggc tagagcgtcc ggttcatacc
      241 cgggaggtcg ggggttcgat cccctccgcc gcgattttta agagcctgga cctttagctc
      301 agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc tacaaggtcc
      361 attgtggcgt tgtaagtttc atatggagga ttacccaagt ccggctgaag ggaacggtct
      421 tgaaaaccgt caggcgggta aaaccgtgca agggttcgaa tcccttatcc tcctttttca
      481 tattatcgcg ggatggagca gtctggtagc tcgtcgggct cataacccga aggtcgtagg
      541 ttcaaatcct gctcccgcaa ttaaaaacta aaaacactgg ttccgtggtg taggggttaa
      601 catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc gccatgcggg
      661 tgtagtttag tggtaaaacc acagccttcc aagctgttgt cgcgagttcg attctcgtca
      721 cccgctttta gttttttatg ggcctatagc tcagctggtt agagcgcacg cctgataagc
      781 gtgaggtcga tggttcgagt ccatttaggc ccattagtac aaaatcttat tggttttggg
      841 gaagtactca agtggctgaa gaggcgcccc tgctaagggt gtaggtcggg aaaccggcgc
      901 gagggttcaa atccctcctt ctccgtttca atattttgtt ttacctggcc cgttggtcaa
      961 gcggttaaga caccgccctt tcacggcggt aacacgggtt cgaatcccgt acgggtcatt
     1021 aatttaatat agttttacat ggaggattac ccaagtccgg ctgaagggaa cggtcttgaa
     1081 aaccgtcagg cgggtaaaac cgtgcaaggg ttcgaatccc ttatcctcct ttttcatatt
     1141 atcgcgggat ggagcagtct ggtagctcgt cgggctcata acccgaaggt cgtaggttca
     1201 aatcctgctc ccgcaattaa aaactaaaaa cattggttcc gtggtgtagg ggttaacatg
     1261 cctgcctgtc acgcaggaga tcgcgggttc gattcccgtc ggaaccgttt ggctcggtag
     1321 ctcagttggt agagcaatgg attgaagctc catgtgtcgg cagttcgatt ctgtcccgcg
     1381 ccattatgcg ggtgtagttt agtggtaaaa ccacagcctt ccaagctgtt gtcgcgagtt
     1441 cgattctcgt cacccgcttt tagtttttat gggcctatag ctcagctggt tagagcgcac
     1501 gcctgataag cgtgaggtcg atggttcgag tccatttagg cccatttatt ttattggccc
     1561 gttggtcaag cggttaagac accgcccttt cacggcggta acacgggttc gaatcccgta
     1621 cgggtcatgg aagatacttt ttgagtatct ttttcttttt atctgaaaga atgattttaa
     1681 aaagcttagc agagttatct ttatggatga ttgtgctaag cttttttgga cagttctaat
     1741 gtaaaatatt tttatatttt ttaagcaaaa aaatgaaaaa atacgagcag aaaactgttt
     1801 tatctgctat acttggttcg ttgcaagttc ccgaaaggat ccgcaggacg gagatgcctt
     1861 gtaaccgaat ttaactaggg ggaatcatta taatggtaga aagacactta tttacatcag
     1921 aatctgtttc tgaaggacat ccagataaaa ttgctgacca aatcagtgat gcaatcttgg
     1981 atgcaatttt aaaacaagat ccaacagcac gagtagcgtg tgaaacgtct gtaacaactg
     2041 gtcttgtttt agtatttgga gaaatatcta cgacggcata tgtagatatt caaaaagtcg
     2101 tacgggaaac aataaaagaa attggttata cacgtgcaaa attcggattt gatggagata
     2161 cagcagctgt attggttgcg attgatgaac aatctcctga tattgctcaa ggagttgatg
     2221 aagcacttga gatccgggat gaagataaaa aagacgtatt agatgagatt ggtgctggtg
     2281 accaaggttt aatgtttggg tttgctgtag atgaaacacc agaattgatg cctttaccaa
     2341 tcgctttgag tcatcgtctg gtacgacgct tggcagattt gcgtaaatca aatgaattaa
     2401 cgtatttacg tccagatgca aaatctcaag taacggttga atatgatgat caaggacaac
     2461 cggaacgcgt agatacaatc gttatttcaa cacagcatga tgatgcagta gataatgaaa
     2521 caattcgtca tgatgtcatc gaaaaagtag tgaaggaagt tattccagct gaattattag
     2581 atgatcaaac gaaatattat atcaatccga ctggccgatt tgtcattggt ggtcctcaag
     2641 gggatgccgg attaacagga agaaaaatca ttgttgatac gtatggcggt tatgctcgtc
     2701 atggtggcgg tgctttttct ggtaaagatg cgacaaaagt tgaccgttct gccagctatg
     2761 ctgcacgtta tattgctaaa aacattgttg cagcagggct tgctcgcaaa gcagaagtac
     2821 agctagctta tgcgattggt gttgctcaac ctgtttcgat ctcaatcaat actttcggta
     2881 ctggaacggt tccggaagaa gaactgattg ctgcagtgag agaaaacttc gatcttcggc
     2941 cagcaggaat catcgagatg cttgatttgc gtcgtccgat ttacaaacaa acagctgctt
     3001 acggtcattt tggtcgtaca gatgtagatt tgccttggga acatacggac aaagtagatg
     3061 cgttgaaagc aagtttagca aaataagtta tattcagctg gaacgatcgc caagtggtgg
     3121 ttgttccagc tttttttatg gcagttaacc tcttgaaaaa gatagtaatt atttatctat
     3181 ttttagatcc tgtcataatg aaagggagga ataagatgaa aaaagaaaca aatgttactt
     3241 tggtcacagt gagtattttc attgcaacgt tcatgacggc tattgaaggt acaatcgtaa
     3301 caaccgctat gccaacgatt gtcggttcat tacatggaat ggaaatcatg aactgggtat
     3361 tttcgattta tttgctgaca aacgctatgc ttactccgat ttacggaaaa cttgcggata
     3421 aagtgggacg gaaaccaatc tttatttttg ggacattatt gtttattatc ggttcgttat
     3481 tttgcggttt atctcaaagc atgattgggt tgattgctgc tcgtgcgatt caagggatgg
     3541 gtgctggggc aatgatgcca gtagctttga cgatcatcgg cgatctttat tctattgaaa
     3601 agcgagcaaa agttttaggt ttgaatagtt cagcctgggg gattgccagt gtttttggac
     3661 cgcttgcggg aggattcatc gttgaaacga tcagctggca ctggatcttt tttatcaatg
     3721 tgccgatcgg aattctatta attattttga tttggctata tttaaatgaa ccaaaaatca
     3781 tacatgagtc taaaccaatg gatatttttg gtagttttag tttgatggcc atgcttgtct
     3841 cattgctgtt agggttccaa ttattaggag acgaaggaat gagtccgctt gtttctgctt
     3901 tgctgctagg tagtatcgta atgttaggta tttttgtttt tgccgaaaaa agagctaaag
     3961 atcctgtcat catgatgcat ttattcaaaa atccactatt tgttgtggtc aacttggctg
     4021 cagcattggc tagtggtttt ttgatgggaa tcgatgttta tatccctatg tggatgcaag
     4081 gtgtattagg gctgaatgca gcaattggtg ggctggtatt agcaccatta tcactagtct
     4141 ggatggtcgg ttctttcctt gcaagcaagt ggatgactca aatgaaaact cattgggtct
     4201 tgagaattgg actactaatc gcagctattg ggggcgcttg gttgtatctt atgcctttca
     4261 gaagtaacta tttatggttt tttgctatat caacggtcat cggtataggc ttaggtgtga
     4321 ccatgactac ctcgactgtc agtgcacaaa atagtgtatc tcgtgaccag cttggtgtag
     4381 caacttcttt taatacgtta gttcgaacaa ttggtcaaac agtcatggtt tctatttttg
     4441 gtttattgat aaatggggta actaaacgag aacttgcagc agcaaattta acaaatgatg
     4501 cagatatcat gaataaactg gtgaatccac aaacggctaa atatattgat gcggatattt
     4561 tgttaccatt aagaaaaatt ctttatgatg ggttacattc cgtttatcta gttggcttgt
     4621 tactcgtgat cattgctttg gtcttaacgc ttttcgttca tgaaaaaagt ggtaaaataa
     4681 aacagtagtt tcggttaaga tatgtacgta gccgaatcat tcaaatttaa agttattcaa
     4741 aaataacttc ttactaagga aggcgaaaat atggcattta ttcaagcaaa tatttattcg
     4801 aatgtgttag aaatggaagt caatctaaat gtgatactac cgcaaacaac aaaaaaggtg
     4861 attggcacca gttcagagca agagacaacg gatatacctg ttttatattt acttcatgga
     4921 atgggtggca atcatagtgt atgggaaaga cgtacgtcga ttgaacgtta tgtagcaaac
     4981 tacggattag ctgtcatcat gccatctact gatcttggct ggtacacaga tacagtttat
     5041 gacatgaagt attggacatt cattgcagaa gagctacctg agatttgtca tgaattattc
     5101 ccgcaattaa caagaaaaag agaaaaaaca tatgccgctg gattatcgat gggcggatat
     5161 ggcgcgttaa aactaggcct tgcaaaatca gaaaatttcg cagcagtaat ctctctttca
     5221 ggcgctgttt ctgtaggaaa tcgaatggat gatcttttga tggttcgtaa agcatctttt
     5281 tgggaaggga tctttggacc attggatcaa atcgaaggtt caaaaaatga tccgcaatac
     5341 ttattgaaag aactagtaaa aagcggaaaa ccagttccaa gattttatat ggcttgtggg
     5401 gaatctgatt ttctttatca ggcaaatcag gaaatggtat ctgctatgca ggaacaaggc
     5461 ttggcggtca cctttgaaca aggacctggc gatcataact ggatcttctg ggaccaatgg
     5521 attcaacgtg cattggcgtg gctaatggaa gaaaaataaa aaaagagtct taaaaagata
     5581 gctcctatag agatcacaaa catagtgatc tctataggag cttttttact gctcgttttc
     5641 tcttctttta ttttgttggc ataagccttc aatataggtt tgtgcactcg ttagaaagag
     5701 tgctttttca ttcaattctg catgggactg catactttct ttaaatccct ctaattgatt
     5761 ttcaactaca taattacgca taaatagaac tgtttctttc aaaaattcat ttccgtccat
     5821 aattttttgt cgaagctgct gttcatgctg ctgatccatt aactgtccaa tcaataaatt
     5881 gtggagagag gcaatggcct gatgactttg ggtgactgaa aatccttcac gaacaagtaa
     5941 ttggatcatt tgctccaaat gttctaatcg actcggaaaa gcgggcacag tattgatttc
     6001 taattctgcc ccacaaggga aacgtgtata aaggtcatag taattttcca tatactgcag
     6061 caactgttca ttccaaggca aagttggatc tggaagcgct aattcttctt ccattgtttc
     6121 agccattttt tgcaagagct gttgtttgtt tttgaaatac caatataaag caggtgcttg
     6181 aacatgaatt ctgtttgcga tgtttcgcat ggaaagctgc gaaagagctt gtgtttcagc
     6241 caggatatca aaggcggcct gaatgatgat tgcttgagaa agctttattt ccattttatc
     6301 aacctcgtgt attgcattat ctttttaaac atggtaaatt gttagtcggt ctaattttac
     6361 agtgttaaat tagtcctgtc aatttaaaca aaggggtgta atcaacgaat gaaattaatc
     6421 ttacgacatg cgaaaaaata taaagtagct gtttttattt ccttgctgtc cgtagcagtc
     6481 atggttgcag cagcattatg gcaacctaag ttactacagc aagtattgga agctattatt
     6541 acagaagata atgatgaaat gaaaacaatt ggtatttacc tgatcagtct ggctttgcta
     6601 ggattagccg caggtgtaac gaacacgatt ttctctgcaa aagtagctca aggcgtaagt
     6661 gcagatatcc gagaagaagc atttcgaaag atccagacat tttcatttgg aaatatcgaa
     6721 cagttctctg ctggaaatct tgttgttcgt ctaacaaatg atatcacgca aatccaaaat
     6781 ttagtgatga tttctttgca atcacttttt cgaattccat tcttatttat tggtgccttc
     6841 attttagcta tgatcacgat gccgcaatta tggtggatca tcgtagcgct tatcgttacg
     6901 gtatttctga ttacggcact ttcatttaca aggatgggca agcacttcat gatcattcaa
     6961 aaactgattg atcgtgtgaa tagcattgca aaagaaaact tactagggat tcgtgtagtg
     7021 aaatcttttg tacaagaaga aaaccaattg aagtcattca gcaaagtaag tgaggactta
     7081 acaaaacaca acatcatagt cggtacatta ttttctgtga tgatcccgtc cttcatgctg
     7141 gctgccaatt tggctgtggt tggggcgatc ttttttgtga gcgatcttgt taaagatgat
     7201 cctacgttaa ttggtggaat tgcttcattc atgaactact tgatgcagat tatgatggca
     7261 atcattattg gcggaatgat gatgatgatg acttcaagag cagccgtatc gctgaagcgg
     7321 attgcggaaa ttttagatgc tgaaccagat cttacttatt tagacgttcc agaacaagag
     7381 ttgacgggtt ctgtcacttt tgaccatgtt tcttttcgtt atcctggtga ggatacagat
     7441 acgcttaaag atatcagctt ttctatcaaa cctggagaaa tggttggtat cgtcggggcg
     7501 actggtgccg ggaagtcaac actagcacaa ttgatccctc gtctatttga tccgacagaa
     7561 ggcaaagttg aagtaggtgg tgtagatctt cgtcaagtaa atgaaaagag tttaagacaa
     7621 acggtttcct ttgttttgca aaaagcaatt ttattctcag gaacgattgc tcaaaacttg
     7681 cgccaaggga aaaagaatgc aacagaaaaa gagatggaac atgcttcttc tattgctcaa
     7741 gcaaaagaat tcatcgaaaa gttatctgat cgttacgaag caccaataga agaacgtagc
     7801 agtaactttt ctggtggtca aaagcaacgt ttatccatta ctcgtggcgt tatcggtaat
     7861 ccaaagatct tgatcctaga tgacagtacg agtgcactgg atgctcgctc tgaaaagctg
     7921 gtccgagaag cactcgatcg agatttgaag ggaacaacga cgattgtcat cgcacaaaaa
     7981 attgcttctg ttgtcaaagc agaccgcatc ttagtattgg atgaaggcag attagtcggc
     8041 gaaggaaccc atgaggaatt ggtagctgga aaccgtgtct atcaggaaat ctttgaaact
     8101 caaaaaggaa cggaggagta agtatgactg atctaataaa agcaagtaaa tttttctatc
     8161 actatttgaa gcggtacaaa ctctcctttt tctttatctt tatcacagtg atcattgcta
     8221 cctatctaca agtaaaggca cctcaataca tcggggaagc ttttcaagaa ttagctaatt
     8281 acgtaggagg cttgatgcaa ggcgtagacg ataaaagcaa atttgtttct gtaatatgga
     8341 aactcttgct gttttatgta ctagctagtg cagccaactt tatctatagt attttgttca
     8401 cacaagtagt agggaagtca acgaaccgaa tgcgtatcgg tctattcaac aaattggaaa
     8461 aattgacgat ccgtttcttt gattctcatc aagacggtga aattttaagt cgttttacca
     8521 gtgacttaga taatattcaa aatagtttga accaagcttt gcttcaagtc atcacgaatg
     8581 ctgttttact tgtcgggatc ttgatcatga tgttccgcca aaatgtagag ttagcttggg
     8641 ctacaattgc ttccactcca gtagccgttt tgatagctgt cttgattatc cgcaaagcac
     8701 ggaaatatgt ggatcttcag caagatgaag tggggaaact aaatggttat atggatgaaa
     8761 aaatcagcgg acaacgtgtc atcatcacaa atggcttaca agaagaaacg attgaaggat
     8821 tcttagagca taatcaaagt gttcgcgaag caaccttcaa aggacaagct tattctggtc
     8881 tactatttcc gatgatgcaa ggaatgtcac tggtcaatac agcgatagtt atctttttcg
     8941 gcggctggtt agcattaaat ggtgatttgg aacgttcggt ggcattaggc ttagttgtga
     9001 cattcgtcca gtattcacaa caatattacc aaccactgat gcagatttca tctggataca
     9061 gcatgatcca attagcgatt acaggggcaa gacgattgaa tgaaatattt gatgaaaaag
     9121 atgaagtcaa accagaaaac ggtaaagcat ttgatggtgt tgaaaaaggt cttgcgttgc
     9181 agcacgtaga ttttggttat tctccagaaa aactagtctt gaaagatgtc tcgatcaatg
     9241 tggacaaagg agaaatggtt gctcttgttg gtccaacagg atcggggaaa acgacgatca
     9301 tgaatctgct aaaccgtttt tacgatgtca atgatggttc agtagtcatc gatggaatag
     9361 atatccgaga ttatgatctt gatgcattac gtagacatgt aggaatcgtt ttgcaagaat
     9421 ctgtattgtt ctccggaacg atcaaagaca atatcacatt cggcaaaccg gacgcttcag
     9481 atgaagaagt catcaatgca gcaaaacaag cgaatattca tgacttcatc atgacgttag
     9541 aaaaaggtta tgatacagag atatccgaag aaaataactt attcagtaca ggtcaaaagc
     9601 agttgatcag tattgctcga acgatcatca caaatccatc tttattgatt ttggatgaag
     9661 caacaagtaa tgtagacacg gtaacagaag caaggatcca aaaagcaatg gatgaagcaa
     9721 tcaaaggaag aaccagcttt gtgattgctc accggctgaa aacaatcttg aatgcagata
     9781 gaatcgttgt cttgcgtgat ggggaagtca ttgaagaagg cagtcatcat gagttattag
     9841 cagaaaatgg attttatgcg gaactttatc ataatcaatt tgtatttgaa agttaaatta
     9901 aaagaacctc gttataacgg ggttcttttt atatatttta tgttgtttgt ttttataagg
     9961 ggcaga
//
LOCUS       DACDLM010000092         9810 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.094, whole genome shotgun sequence.
ACCESSION   DACDLM010000092 DACDLM010000000
VERSION     DACDLM010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9810)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9810)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9810
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.094"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(33..2153)
                     /locus_tag="IV356_002532"
     CDS             complement(33..2153)
                     /locus_tag="IV356_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAP9016157.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYISAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2383..3561
                     /locus_tag="IV356_002533"
     CDS             2383..3561
                     /locus_tag="IV356_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HAP9016158.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3577..4335
                     /gene="aroD"
                     /locus_tag="IV356_002534"
     CDS             3577..4335
                     /gene="aroD"
                     /locus_tag="IV356_002534"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HAP9016159.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4358..4843
                     /gene="ybaK"
                     /locus_tag="IV356_002535"
     CDS             4358..4843
                     /gene="ybaK"
                     /locus_tag="IV356_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HAP9016160.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4914..6167)
                     /locus_tag="IV356_002536"
     CDS             complement(4914..6167)
                     /locus_tag="IV356_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP9016161.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6284..7633
                     /gene="gdhA"
                     /locus_tag="IV356_002537"
     CDS             6284..7633
                     /gene="gdhA"
                     /locus_tag="IV356_002537"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HAP9016162.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7745..9091
                     /locus_tag="IV356_002538"
     CDS             7745..9091
                     /locus_tag="IV356_002538"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HAP9016163.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9399..9785)
                     /locus_tag="IV356_002539"
     CDS             complement(9399..9785)
                     /locus_tag="IV356_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAP9016164.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         3127 a         1782 c         2010 g         2891 t
ORIGIN      
        1 attttgtcgc tgctcctttt aaatttattt tatcattcgg aagaacttgt ggtcgttccg
       61 tgaagttctt ggtacgtttg cgttttataa agatcaacag ttgattgtcc gttgtgttca
      121 ctaaagacac tagttgactt gtcaccaaga gatttttcag cttcttttaa tttctctaag
      181 ccattcttgt agtcataatc actggtatca attgggtcta atccactatt cgtatagaac
      241 cgaagaagat caccattatt gatttggtca gaaacagcta actgtttatc aactttttct
      301 ttcagtgaat caatttcatt ctgtacttcc tcagtaggtt cagtaatagc ttcaccagtt
      361 tcgttactat agatcgtacc accgtagtaa gtatattttg gtgtaacaaa atcaccatca
      421 cggaaagaaa caagctgttc atgatctttc gagaatagat cttgtcctaa ctgaatataa
      481 ttttttgtat ctacacctag taagtgaagt aatgtaggca aggcatcaac ttgtccgccg
      541 taagtgtgat tgattccgcc ctgtgtttgt ccagggatat ggatcatata agggacacgc
      601 tgcatttgtg cattgtcgta gtttgtccaa gtagaacttg tttttccaac taattcagct
      661 agatttttat ttcttgaatt cgagacaccg taatggtcac cgtaaaggac gatgactgaa
      721 ttatcataca agccgctttc tttcaaataa ttgaagaatt cttgtacggc ggtatctaaa
      781 taattggctg tcgcaaagta accgttgatc gtttcatcat ttgtattggc taacgggaat
      841 cctgcttcgt cattggtgaa ttttgaataa ggataatggt tagatacagc aatgaatttt
      901 gaataaaatg gttgttgcag acgttccaag tattgtacgg attgttggaa aaatggttta
      961 tcatgcaacc cgtattggaa cgaattgtca tcattaacat cataataaga agaatcaaag
     1021 aaataatcat atcctaaatt cttgtatgtc tcgtttcgat tccagaatgt accagcgttc
     1081 ccatggaata ccgcactaat gtaaccttgt gtttgactta aaatatcagg tgcagcttgg
     1141 aaagtatttt ttccgcctaa ttgtgtgaac aaggagcctt gattcaagcc aaacaatgaa
     1201 ttttccatca gcgtttccgc atcgcttgtt tttcctgctt ttacttgatg gaaaaagttg
     1261 tcaaaactga acgtgctgtt gctgtggtaa agactattga tgaaaggtgt aacttcatgc
     1321 tggagaccat tctcatctgt caatttataa tcgatcagga attgctggaa gctttctaaa
     1381 tggatataaa tcacattttt tcctctagcg agcccgaaca aatcgtcatt tggtgctgca
     1441 taatgttctt ttacataatt ttctacttct ttcatatcat tgggacttgc ttctgcccgc
     1501 acttggtttg tctggtaagt ttgaacaccg tcataaacca tgaaagcatt caagccaaga
     1561 tatttgacca aataatcacg agagaatgtt cgagtcagca attctggacg atcagcttcc
     1621 gccataaaaa gatttcctga gaaaatcata actgctaatg tagagatcgc aaaagccatt
     1681 cttgctcgga tcgggcgagg gtccaacttg attttttttg caatcagcag aacagtcaag
     1741 ataataaaat cgatccaata gatcacatca tatgggcgaa acagtcgaat ggcactttct
     1801 cccagaccac tcgctacttt cccagcacct aaaatcgtgt tgatcgtaat gaagtccgtg
     1861 aattctcgat aataagtgac attcgaaaaa acaagcaatg tcaaaagaaa ataaatgacc
     1921 atcatcgtga tataagcaac tctagggcgt ctgatataaa gagcaattcc aagtaataac
     1981 aatgtagttg caatagggtt gataaacaag ataaagtatt gaatgccact ttcgattccg
     2041 agatggaaat caactaaata ggcaaaaatc gttttcaacc aaagtaaaac gactagtaaa
     2101 gaaaaaaatc cgagcctctt attcaaaaag gcaggtgttt ttatacattt caagataatc
     2161 ttcctttctg cacttcttaa tcacagaagt gtcctgaaac catgttacac agctcactta
     2221 ttctcattta ttttactagt atgacaatat agtgtcaatt gaaaccagaa gtttatgctg
     2281 tttcattaag gttttcttta agcttcatga aaaaatgagc agtaagacaa gtcctatgtt
     2341 ttttgttata cttgggaaga gaaagctaaa gcaggtgaag gaatgaaagt aaaagtaaaa
     2401 aaaagagcaa gcaatcgatt gaaaaaagga tatccactga tccaaaaaga agaccttgct
     2461 catccccaaa aagaaaccac gcaatgggtg gaattagttg attcgcaaaa ccaatttatc
     2521 gcaaaaggat atctaggaaa gcagaataag ggaatcggtt gggtattgag ccagcagaac
     2581 atcccatttg atcaatcttt ttttgaagaa ttttttgtga agtcaaaaga aaaaagaact
     2641 ttcttttttt cagatgattc tactaccgct tttcgtatat tcaatggaga aggagacggg
     2701 atcggcggtc tgattgttga ttattatgca ggttatgctg ttttttcttg gtataacgaa
     2761 acgttatatg cacatcgtga attattgatt caagcttttc gtgaaatcta cccggaaatc
     2821 ataggaggct atgagaaaat tcgatttgaa tcagtaaatc tgcctgagag ccagttcatt
     2881 tacggaaaag aggcaccgga acccttgatc gtaaaagaaa acggagtaaa atttgccgtt
     2941 tatttaaatg aaggattaat gactgggatc tttttagacc aaaaagaagt acggggatca
     3001 ttagcagaag gtttcgcttc tgggaaaaca gttttgaaca tgtttagtta taccggcgcc
     3061 ttttctgttg ctgccgcaat gggaggggca atcgaaacaa caagtgtcga tctagcaaaa
     3121 cgcagtttaa aaaaaacaca ggaacagttt gaagtgaatg gtttggatgt cgatcagcaa
     3181 aaaatcattg ttatggacgt attcgagtat ttcaaatacg ccaaaagaaa acaattttta
     3241 tatgacatga ttgtattgga tccaccaagt tttgccagaa ataagaaaaa agtctttcgc
     3301 gtagcaaaag attatgggga actggtcaag gatagtctgg atattttagc agaagacggg
     3361 atacttattg cgtctacaaa tgctgcgaat gtctcgatag aacaattcca aacaatgatt
     3421 gaagaggaat tccatgccaa aaatgtttct tttgaacaac ttgctttata tcgtctgcca
     3481 aaagatttcc agacgacgga taccttttta gaaggcaatt atctgaaagt gtttgtttat
     3541 caaattaaaa ataaccatta gaaggagcga tgcagaatgg ttcgggtaaa gggattgaat
     3601 ataggaagcg gtagaccaaa gatttgtgcg cctcttatcg gggccgtccg agaggaagta
     3661 ttacgtgaag cagttcttgc acgtgaagca ggggccgatt tagtcgaatg gcgagtcgat
     3721 cattatcgtg aagttttttc ttttgatgaa gtagcagaaa cattggttct tatccatgag
     3781 atgcttgatg gactgccgtt attatttacg tttcgtacct tagctgaagg cggagaacaa
     3841 gacatatcga tccgtcagta tcgcgacctt tatgaacatg tgatacacac aggattagta
     3901 gatatggtcg atatcgagtt gttcaaagta gaaagtctag gaaaaagact gatagaggaa
     3961 atcaagtctt taaacattcc tttaattatc agtagtcatg attttaaaga aacaccagca
     4021 gaccctgtct tgctttaccg attgaatgtt atggaacatt ttggagccga tatcggaaaa
     4081 ctggcagtaa ctcccaataa tgaacgagat gttttgcggt tgatggagtt gactagacgg
     4141 gcaaatgctt ttgtctccat gcctattatt acgatgtcca tgggaaatct tggtaaaatt
     4201 tctcgtctgg ttggcggaac gacgggttcc gttatgacat ttggttcctt aagcagcgat
     4261 tctacttctg ctccaggaca attaccggtc aaagcattga agcaaattat tcaattatta
     4321 aatgaaccgt tgtagaacaa gtttgaggtg atattttttg gcaaagaaaa aaatagtaaa
     4381 aacgaatgca atccgtatgg tcgaacaaaa aaagattccc tatacagagc acgaatatga
     4441 gtgggacgaa agccacctaa gtgcgtcatc ggtcgctgaa cagcttccag aaagccaatc
     4501 tcgtatattt aaaacactgg ttgctgtggg caatgtgacg gggcctcttg ttgctgtgat
     4561 accgggagaa gccgaattga atctaaaaaa attagcaaaa gtttcaggga ataaaaaagt
     4621 agaaatgctc catttaaaag atttggaagc aacgaccgga tacatacgtg gtggctgctc
     4681 gcctataggt atgaaaaaac tatttcctac ttatttagat caaattgcag aaagctatga
     4741 acaaatcatt gtctcggctg gcagaagagg gctacagatg gagttagcac ctcaagatat
     4801 ctgtgcatta acgagcggac aatttgcaga tataaaacaa taaatcatac gtataaaaga
     4861 aagaaggagg ccgggatgtt gtttgtccag tctccttctt tcttttttat acattatgct
     4921 ctttgcccgg cattcattcc tgctacatgc cctgtagcga aagccgctgt gatattaaag
     4981 ccgccagtat aaccattgac atccagtaat tctcccgcaa aatacagacc atcaatgatt
     5041 ttactctcca atgttttagg ataaatttcc tttagagaaa cccctccgcc agttacaaat
     5101 gatttctcaa taggaaaagt tttgttgatt gatagcttaa actctttgca tagttgaaca
     5161 aaatcttgaa tttgtttttg agaggcttgt tgtcctgtca gatgatccat ttcaagccgc
     5221 tcaagaaaga aaactaacaa tcgctcaggc aatataccat gccaagcatt gaccaagttc
     5281 tttttggttg ctttactttt ttctgtcaat atatgaataa gctcttgttt ggtttgtgta
     5341 gggaaacaat ccagagaaag tgtcactggt tctcccgttt tctctaattc tttattgaca
     5401 aaacttgaac aacgcagtgc agccggacca gaaataccga aatgggtgaa aagtaaatcc
     5461 atcgtatgtt cagtcaatac acgacctttt ttatttaaaa cgcgtaaagt gatgtcttgt
     5521 aaagaaagcc cttgaagtgt tttctcctga atatacggtt catccgatat caagggggac
     5581 tctgtcgcat aaagaggcgt caccgtgtga cccactcgct tcacgatctt gtacccatct
     5641 ccagtagaac cagtagatgg ataagtccgt ccaccagttg ttaagataat ggcaggagca
     5701 tggaactctt cgaattccgt gcgtataccg taaattttat gttctttgtg gatcaatttc
     5761 tctactcgag tagagaatag aagcgtcaca tctagttctt tcagacgatt gagcaatgct
     5821 tcgataatcg tttttgattt atttgttaca ggaaacatcc gtccatgatc ctcttctttt
     5881 aaatgtacgc cttgtgattc aaagaagttc atgatatcga aattattcca ttgcgcaaac
     5941 gtactatata aaaactttcc atttccagga atatgtgcaa tcaaatcatc aacaggacga
     6001 ttgttcgtaa cattgcaccg accaccacct gtcatcagta gtttttttcc tgcttttttg
     6061 tttttttcga tcaagagtac gcgtgcgcct tgttcagctg cactgatcgc tgccatcatc
     6121 ccgcttgttc cagcgccgac tacgatcaca tcatacagtt tttccattcc ctcacctcaa
     6181 ggaaagtgta gcatatctga agaaagaaaa cagaaaaaaa tgttttgagc caaaagagaa
     6241 aatgagctaa aatgagggaa gataagcaaa ggagcgtgga acgatgacaa acgcaacaga
     6301 atatgttcaa gcaattcaag aaaagctaca tcaaaaggat caagggcaag aagaattttt
     6361 acaagcaatc gatgaattca tgcccacggt tatgtctttt ttggacactc atcccgaata
     6421 tatcgaaaag aatatcttag aacttttaac ggaaccagaa agagttattc aatttcgagt
     6481 gccttggcaa gatgatgaag gaaactggcg agtaaataga gggtaccgta tccaatacaa
     6541 ctcagctatc ggcccttata aaggtggatt gcgcttccat cctagtgtca atctaagtat
     6601 cttgaaattt ttggcttttg aacagatttt caagaatagt ttaaccggtc tgccaatcgg
     6661 tggaggaaaa ggcggaagtg acttcgatcc taaaggaaaa tctgataatg agatcatgcg
     6721 tttttgtcaa agtttcatgc tggaattgtc aaaacatatc ggcccatcga ttgatgttcc
     6781 tgcgggagat atcggtgtag gagctagaga aatcggctat ttgttcggcg aatataaacg
     6841 attgaaaaaa tatgatactg gtgtgttgac aggtaaacct ttggattttt ggggaagtaa
     6901 gatacgtacg gaagctactg gttatggatt agtgtattat gtcaaacatc tattgaacga
     6961 agaaaaagat tcatttaatc aaaaaacagt ttttgtttcc ggaagcggga atgtagccat
     7021 ttatgcaatc gaaaaagtgc aagagctagg cgggaaagtt gttacatgtt cagattctag
     7081 cgggtacatc tatgatccag aaggaataga tgtgaaacta ttgaaagaag tcaaagaaat
     7141 caatagacaa cgtttgacgg aatacgcaaa ccaacgtcct tctgctattt atcatgctgg
     7201 agaatctgtt tggacattga aagaaaaagc ggatatcgct ttgccatgtg ctactcaaaa
     7261 tgaaatagac gaaagcttgg ccgaaatctt agtagaaaat gggatcaaaa tcgtagcaga
     7321 aggcgctaat atgccatgta cagtaaaagc tgtttctgtt cttcatgaag caggcgtgtg
     7381 gtattgtcca ggaaaagctg ctaatgctgg aggagtagca gtatctgctt tagaaatgag
     7441 tcagaacgtc cagcgattga cttgggaaag agagcaagtg gatgagcagc tggatcaaat
     7501 catggaaacg atttaccata cgtgtcgcca aacagcagcc gagtacggcg acgaaaaaaa
     7561 tctgcttctt ggagcaaatg ttgctggatt tgaaaaagtt gccaaagcaa tggcagcaga
     7621 aggtttagtt tgaaaaatga aactttcttg gaaatattgt cagcattttg tttatttgct
     7681 tgaaaaataa taaaaaaaaa cgtaaagtat tacctgtaga gtaaacctat aaggaggaga
     7741 acaaatggca cacattcatt ttgactattc aaaagtagca ccgtttgtca acgaacaaga
     7801 gttagggtac atgcaaagcc aagtaacagc agcccacaac gaattacggg aaggtactgg
     7861 cgcaggaagc gacttccgcg gctggatcga tttaccaacg aactatgaca aagaagaatt
     7921 tgcacgtatc aaagaagcag ctaaaaaaat ccaatctgat tctgaagtat tagttgttat
     7981 cggtatcggt ggttcttatt taggcgctcg tgcagcgatc gacttcttga atcacacatt
     8041 cttcaattta ttagatagca acacaagaaa agcaccacaa atcttctttg ccggaaattc
     8101 aatcagctca acatatattg ctgacttgat cgaagtaatc ggtgatcgcg acttttcagt
     8161 aaacgttatt tcaaaatctg gaacaactac tgaaccagcg attgcgttcc gtgtattcaa
     8221 agagcttctt gttaagaaat atggacaaga agaagcaaac aaacgtatct acgctacaac
     8281 agataaagca aaaggtgcag ttaaagtaga agcagatgca gaaggttggg aaactttcgt
     8341 gattcctgat gacatcggcg gacgtttctc tgtattaact gctgttggtt tgttaccaat
     8401 cgctgttagt ggtgcagata tcgatgcatt gatgcaaggt gccgctgatg caagcaaagc
     8461 atactcaagc gacaaactag aagaaaacga agcttaccaa tacgcagcaa tgcgcaacat
     8521 tctttaccgt aaaggcaaag taactgagtt gttgatcaac tatgaaccag gaatgcaata
     8581 cttctcagaa tggtggaaac aattgtatgg tgaatctgaa ggaaaagacc aaaaaggcat
     8641 ctatccttca agcgcaaact tctcaactga tttgcactct ttaggacaat tcatccaaga
     8701 aggacgtcgc aatatttttg aaacagttgt gaaggttgaa aaacctcgta aatcaatcac
     8761 aattcctgaa caagcagaag atttagacgg tctaggctac ttgcaaggaa aagaagtgga
     8821 cttcgtaaat acaaaagcat ttgaaggaac attgcttgct catacagacg gtgacgtgcc
     8881 taacttgcta gtcaaaattc cagaaatgga tgcttataca ttgggttata caatgtactt
     8941 ctttgaaatt gctgtaggta tttcaggtta cttgaatgga atcaacccat tcgaccaacc
     9001 aggtgtagaa gcttacaaga aaaacatgtt cgcacttcta ggcaaaccag gctttgaaga
     9061 tcttgctaaa gaattgaacg aacgcctgta agataagggt ttttcgctag atttaaataa
     9121 tcagtgatag aaacatgttc gctttaaaat gaaaactggt acccatttag gtactcaaac
     9181 atactgcatc gtttattcag aataaggggc tgtgacaaga cgtttgtcac agtcccttgt
     9241 ttgtatagaa atcgattgat tgccttgctc tttagtttgt tttaggactt taagaacagt
     9301 gaggctgact tcgaaggtta attctgtttt tttgttttct agaatcagta agcaaaaaag
     9361 cactcacttc gagtgctttt ttgcgatata ttcttagctt aagataggcc taatttttct
     9421 tttacagatg agggtacctt atcgctggta attacttttt tctctatgat ccgcttttcg
     9481 cttgctttca actgcaagat cgttccttcg gggtaagcag aaccattggc agagtcacca
     9541 gaagtaatga catcgaaatc taactgtctt ttttcaccgt tttcagcata agcatctacg
     9601 ttgtatttaa aacctcttcc aattacttcc ccattatctg ctttgatatc agtttctgca
     9661 ggcattggag ctttgactac cgcataataa tctttaccta cataagtaga ctgatagtag
     9721 tcccaacctt tccatcctat aaaagcaatc aatatgataa cgatcaaccc taaaattttt
     9781 ttcatgaaag atctcctttt ttatttttat
//
LOCUS       DACDLM010000093         9667 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.095, whole genome shotgun sequence.
ACCESSION   DACDLM010000093 DACDLM010000000
VERSION     DACDLM010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9667
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.095"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(174..1946)
                     /locus_tag="IV356_002540"
     CDS             complement(174..1946)
                     /locus_tag="IV356_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002841847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9016165.1"
                     /translation="MRMQMIGGLTMKSFYKNKFALTNQGAEDLVKASISSFFVYCINM
                     VPAFIIMMLIDELVLENVKPPWLYFTVSFVTLLFMYWLLDREYENLYNSTYKESAHLR
                     MQIADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVM
                     LLVGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEI
                     NSFNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLL
                     TGEVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSP
                     LKSFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDY
                     DEGCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAA
                     RLANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLD
                     AENEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKIVDQGTHSELYRRSE
                     IYKNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(1900..3654)
                     /locus_tag="IV356_002541"
     CDS             complement(1900..3654)
                     /locus_tag="IV356_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9016166.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLK
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(3764..4333)
                     /locus_tag="IV356_002542"
     CDS             complement(3764..4333)
                     /locus_tag="IV356_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HAP9016167.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(4351..5775)
                     /locus_tag="IV356_002543"
     CDS             complement(4351..5775)
                     /locus_tag="IV356_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAP9016168.1"
                     /translation="MKELFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSG
                     KSTLLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTN
                     TTSELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLS
                     LNSKLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVK
                     NRTVKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDIN
                     FDVKVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQF
                     FTESVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSK
                     TNLFLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGG
                     IKKDIKLRVEDSTLIEQIFNDITK"
     gene            complement(5777..6445)
                     /locus_tag="IV356_002544"
     CDS             complement(5777..6445)
                     /locus_tag="IV356_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAP9016169.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFGTSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(6576..7160)
                     /locus_tag="IV356_002545"
     CDS             complement(6576..7160)
                     /locus_tag="IV356_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP9016170.1"
                     /translation="MESGLSHFEKVGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(7491..7724)
                     /locus_tag="IV356_002546"
     CDS             complement(7491..7724)
                     /locus_tag="IV356_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HAP9016171.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLTKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(7739..8689)
                     /locus_tag="IV356_002547"
     CDS             complement(7739..8689)
                     /locus_tag="IV356_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAP9016172.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(8686..9528)
                     /locus_tag="IV356_002548"
     CDS             complement(8686..9528)
                     /locus_tag="IV356_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAP9016173.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
BASE COUNT         3263 a         1760 c         1268 g         3376 t
ORIGIN      
        1 tttaaaactt tgattattcc ttatattata agaatagaca ttaagtgaac taattcaatc
       61 atactgattc tttcgtgtat tcaaaattag atgctgttta ataaaattat tctttttgaa
      121 aaagaattat aactatatcc caaaaattgt aggttaattt aaagcctatt tcatcatcgt
      181 gattgagctt ctttttcata gacgaatttc tcagatagtt tagttttctt tatgagattt
      241 ttgtatattt ctgaccttcg atacaactca ctatgagtac cttgatcaac tatttttcct
      301 tgatccatca ctacaatttt atttaccttt tcaatagact tcaagcgatg cgatataatt
      361 agtactgtct tatcttgtat taaacgattt aaactttcct gaatacgttt ttcattttcc
      421 gcatctaaac tggcagtaat ttcatctaaa attaaaattg gcgcattttt caaaaaagcc
      481 cgtgctatgg ataggcgttg tcgctctcct ccagaaagtg aacttccgtt ttctccgacc
      541 aatgtatgat aaccgtcagg tagtttttca ataaagtctt cgcagttagc taaacgagct
      601 gcttttttca cttcctcatc tgacgcttga ctatttccaa tacgtatatt ttccaaaata
      661 cttgtattaa acaaagttac ctcttgaaaa acaatagcga ttttgctaaa caaagaagct
      721 ggagatacac gtttaatatc atacccatca attaaaatac agccttcatc ataatcatac
      781 agtctagaca ctaatttcaa gatactagtt ttcccggaac cactagcacc tactaacgca
      841 gtcacttctc cttgtttagc cgtaaaagag atatgatcta aaattggggt attgttatca
      901 tatgagaaag agacatctcg caactcaatg tcaaaagatt tcagaggact atctgatccc
      961 tcttggatac tggtttcctt catagctcta attcgctgta ttttaggagc taaataaaat
     1021 atttcaagca ctgcttcttt catagaatcg aaggaatcct ttatttttat tgcggctagt
     1081 aagtaaccaa cgacgtagag tatagtcact tcacccgtta acagtaagtg aacacctact
     1141 agaatgacta ctgctaaact aacatatgag aaaatagagg ataaggccat gactgaaaaa
     1201 gtacttaatt ctacctttaa atgaatcctt tcactctctt ccattttttt gaaaagtctg
     1261 tcttgaactt ttttagatag attaaagcta ttaatctctt gctgcaattc tatagtttct
     1321 tgaaattctt ccgagttttc tctcaaagta tcgtaatatt tagtattggc tttcgtttgg
     1381 gatttctttg ataacaagat taagacaaaa ctaaataacg ttggcaaaat aacagctaat
     1441 cccattttga cattaccaac caaaagcatc actgaaataa aagggaaaaa cagagccata
     1501 ccgccggctt taggtattgc atgactcatc gcatgctcaa taccttcaac gtcagacatg
     1561 atagtttgag ataaatctga taaattatgt tttgaaaaat aggataatgg taaatttgac
     1621 aaatcgtctg caatttgcat tcttaaatgc gcactttctt tataagtact attatataag
     1681 ttttcatact ccctatctaa caaccaatac atgaaaagca aagtaacgaa cgatactgta
     1741 aaataaagcc aaggcggctt tacattttct aaaactaatt cgtctatcag catcattata
     1801 atgaatgctg gtaccatatt aatgcagtat acaaaaaagc tagaaataga tgctttaacc
     1861 aaatcttctg cgccctgatt agttaaagcg aatttgtttt tataaaaact tttcattgtc
     1921 aagcctccaa tcatttgcat tctcataatt agtgaccaat tgtttataca cttgatgttt
     1981 agccattaat tcattatgat ttccacgttc tactattttc ccttctgaca agacaagaat
     2041 ttcatctaca gatttaatgc tggataatcg atgagctatc ataataactg ttttttcttt
     2101 catcagatgt tgaaaagcct tttgtagttc atactcatta tctggatcaa tagatgcact
     2161 ggcttcatcc ataataacaa tctttgcatc ttttaaaatt gctctggcaa tagctatacg
     2221 ttgtttttct cctcctgaca gataaactcc tttactacca attaaggtat gctctctttc
     2281 gggaaatttt tctaaaatcg attcgcaacc ggctaatctt agcgcgtcaa atactttact
     2341 tgctggcgct tgaggatttg ctatagaaac gttatcgtaa atactctgat tgaatagttt
     2401 cgtatcttga aagacaaaag caattgtgtt aataattgtg tcttttgaat agtgatttaa
     2461 aggcttacca ccaattttaa tctgtccctt atccacattg tagaaacctg aaattagttt
     2521 agctatcgta ctctttccgc ttcctgattt tcctactaat gcataaattc ttttttgttc
     2581 taaaactaag ttgaaatttt ctaaaacaca ctcttctttg tatgaaaagc tgacattttc
     2641 aaatgcaatg tcacaatttt taatctgtgt ctcgttccca tattttagtt ggtcttgctt
     2701 catttctaaa taaagggagt ctagtgtttc gactgcatat cttgcttcaa acaagtgcat
     2761 acttacatac attattctca tgaaagaaac aaaaataatt ccacttaaaa aaaacaacat
     2821 caacaagtca acagctaata tcttgggagt ggtaagagaa gttataaaaa aggttatagg
     2881 aactatcaaa atgcaaacta tgccaaaaaa tagccattga aaaagaacaa aaggtgtttt
     2941 cccactcaaa gaatacttat atgcaaactt agcataatcg ttaattgctt tattcaaggc
     3001 tttaaatgat gttactttag caccaaatat ctttataact tgaattcctc ggatatattc
     3061 taccgtttca gagcttaaca catctaacga ttcttgatat ttttgaataa aatttgtatt
     3121 ctctgtcatt ttctttaaca agaatacacc aattactaac atggcgatta gaaccaatcc
     3181 aattttaaaa ttaatgaaaa agcctaaggc aactgataaa acaggtgtta ctatggcttg
     3241 agcactatct ggaatcaagt gagcaattgc catatgtgtt ttagccgcgt tgtcatcaat
     3301 tgtctttcga atatatcccg aagaatttaa atcaaaaaaa cgaaaacttg cttctgttaa
     3361 accgctaatt cccttttttc tcaaattagt ctctaagcga aacccaagga tatgagaaaa
     3421 taagccagaa aaaatataaa ataaagctcc taaagttaac caagcaacag tttgaaccgc
     3481 ataactctta gctaaatatt catctcctac aataattaga gacttaagaa atttgtaaat
     3541 actgtaatat ccatagactg ttaatacgac agaaaaatca gaaaataaag tggctaacca
     3601 tccgtagtat ttcattttag ggacataact aaataatttt ttgtatactt tcattttttc
     3661 ctcccccgca ttcaatttct tctcttattc gtttacaact gttaatgctt tccgtaatag
     3721 cgtaaattag agatgtacaa acagatagaa ggtaaactac gttctatttt ttgtattttt
     3781 ttaagacttt tcttccaatc aatacaccaa tcatagataa acttgctaca actaacactg
     3841 aaatgattcc ccatatacct accgcatagt ggatcattgc atccattgtt gcagcagatt
     3901 gtcctttatc tatccaatct tgacgaaaac gatctgtaaa gaaccatata ggaatccact
     3961 gtccggcagc actgcctaat tgcattagag cccaagacgc aacttgagga attgctcgat
     4021 catatccaaa tacagataga ataatatcag ctaagatcgc catactaatc gaactgataa
     4081 accaaggtaa gtacgccccg cccattaacg taaaaaataa caataaaaca attgtgtaaa
     4141 tagtaaaaat tccttttcta gggtagttat agctaatata aacaaatatg attccagata
     4201 ataatccaaa aatccctggg gatatgctgt gaccaaacgc cccaccaata ctactaacca
     4261 ttattgaaaa aaagtaaatt actagggaaa taactgtagc taaaccaata aaaatataat
     4321 cttttgtttt catatatatt ctcctcaatt ctatttcgtt atgtcattaa aaatctgttc
     4381 tatcaaagtt gaatcttcta ctctaagttt tatatctttt tttattccac cattttttaa
     4441 ataaataatt ctattgcatg ttttataaag aaattccgga tcatgagtgg ctataactac
     4501 tgcacccttt tcttttaagt ctttaataag gtcagcaatc ctttccatat taatataatc
     4561 caacccactt gtaggttcat caaatagaaa taaattagtt tttgacaatg aagctataga
     4621 aaccaataat ctttgttttt ctccaccgga taaatcaaac ggtaattgat ctttcatttt
     4681 ataaagttcc atttttttta aaattttttc ttgctgatct ttactaacta tttcattccc
     4741 cagggctaac tcgctcctca ctgattctgt gaaaaattgg taatccattt cttgcattac
     4801 taaaaacggc gatgacaaat tttttttatt ttcgattatc tttcctttgg tagggcgaat
     4861 aatcttcatg agtattctta gtaaggttgt tttccccaca ccgtttttcc ctaccaaacc
     4921 aataacatct ccaactttga catcaaaatt tatgtctttt agaatatttt cataagtaat
     4981 ttcttcaact tttaatacat ctgcacttac cttttcgata tagggaactt caatcgaact
     5041 attaaaaatg tcaaatttcc ttaatgcgtt attgttttca gtttttaaca actgaatagt
     5101 tgtagttttt acagttctat ttttaacaaa tagaacttga tcaattaatt ctttcaaata
     5161 gtaaaaacga tgttcagcta taacaatagt aaatccttta ttttttaaat cacaaagtaa
     5221 gtcagcaagt ttcttagtcg ctttgaagtc caaatttgaa gacggttcat ccaatataat
     5281 taatttagag tttagcgata aactacatcc aatagaaatt ttctgccgtt caccacttga
     5341 tagcgaaaaa atgtttttat ctaatatatt tgaaagatct aataattcag ctaattcatt
     5401 gattctttta tccatatgct cttttgtaaa tccaaagttt tccatcgaaa atactaactc
     5461 actcgttgta tttgttgtaa agaattgtcc tctaggatct tgacttacgt agccaatatt
     5521 ttttgatata ctttcttgtg ttaaggattg tagcgagtta ttttcaaata aaatttcccc
     5581 aaccaatttt ccgtcataaa gtcttggaat aagtccattc attaacttta atagtgtgga
     5641 tttcccactc ccagaagaac cagtaatcaa tgtaagacta ccttttttta ttgaaaaatt
     5701 aaggtcaaca agcgcttgtt ccttaacatc cttatatgaa aaagaaacat tgttaaattc
     5761 aaacaattct ttcacctcaa atcaaaatac ttaagaaaaa aatagtaacg gaaaacagga
     5821 tgatatagtc taataagctc atgtttgttt tatagtaaga acttcttttc acaggagatt
     5881 ctatcccctt tgttattgca ttagcggtca tttcttcagc aatcatagtt gcacgtataa
     5941 gaacgggaac taacagaaat tccaaatatt gcagaggctg aaaaaaagac aagcgaatgt
     6001 ttctcatttt taaagattct ttaatcattc ttatttcaga acgataagtc ggaaagaatc
     6061 tgatcactac tgtaatactt aacattattt ttttcggtaa atgtattttt tctaaagagg
     6121 ataataattc attgctagta tagacactaa ccaacaacca tgagatcatt acgaccggca
     6181 acattcgaaa tacaatatat aaggatgtcc caaaaaatat agtaaaaaac tctatcttga
     6241 tagcatcaat aattttcatt actaaaaaca gaactgaata aatcaagatg aaataaatac
     6301 atgtctttat tttacgaaac atcaatacta aaactgtagc aataatgaaa caccccactt
     6361 gaaatatatt tccctttcct aaaaaaataa tgaccggaaa aaaaatattt aaagtaatca
     6421 aggttaacgg attgattttt gacactcttt cacctccaaa aaataagatc gcactgttat
     6481 cttaagctga taaaaatgca ccgttattca gataacagtg cgatcttatc aaaaagcata
     6541 actgagaaca attctcaatg caagcttttt tttaattaac tcagtaattc aatccaccca
     6601 ggaacagaaa attgatacaa tcttctggtt aatagcatag tcttttcttt tgaatagcta
     6661 tgcttcaata tatcatagaa tgtagcgtag aatgagtaaa tgtagaagtg gatttcttct
     6721 tcattaaaga ctaaattttg attgatcatt ccgatagtct ttaacttatc tagacaacag
     6781 actgtctttt ttgtcacaaa tgatgtaatt ttttcaacaa tatcttgata tttggttcca
     6841 gctgattgga ataaaaccaa atcgaatata cgtttattct caaaaatata attaataaat
     6901 ggatctaatt cattgaagtt ctctctccaa cttttctcta tatctatatt ttctaagttt
     6961 aagaggtatt tggtaaactc ttcattatac atattaataa gcgcattaat atgcggctga
     7021 ataatttctt caaatagcgc ttccttagaa gtaaaatgtt tataaaaagc acccgtagtt
     7081 acgcctgcgg tcaagcacag ttgccttatc ttagtttgct gaaatcctac tttttcaaaa
     7141 tggcttagtc cactttctat taatttttgg tgagttgtaa tataatctct ggtttctatg
     7201 ggtacttcct cctaataaga tgaattaact atattatctt acacaggact tgaagtttca
     7261 atcgttaacc tctattactg aactcattcc ttagagctaa actaatgaga aagagcaaaa
     7321 taactgatac aaaaagcaat cctacaagaa ttaatagact catctaaatc attcaccttt
     7381 tctaaaataa tccgagaaag atttaaaaaa attatatcca gctattagga taagtcctat
     7441 cataatcact ccaatagcca ttttcttatc ctccctaaaa ataaagcctt ttacttaaaa
     7501 ccttttttgt aatcgtcaat aaattttttc cctttatcag ttaattgaaa tcctatatct
     7561 aaatagtcct catatctaag tttagtcagc atctcactta cagatgctgg actaacactt
     7621 agaacttttg ctaaatcatt attttttaat ttcttttttc tttttgataa ttcctgaatt
     7681 gctagtaaat aaattagtat agtagttgtt ttaatttgta ccatacctac cctccaaatt
     7741 atttcgaaag gccttcagca attttatcca ggttccattt catcatcgca tagtaactat
     7801 caccatcttg tcctttttct gcaattgaat cagtaaaaat cgttgaatag ataggaatat
     7861 tggtatcttt tgatactgtt ttcattggtc tatcgtccac actgctttct acgaataagg
     7921 agggaacttt tgttgtgcgt aatttttcaa ctaagtgttt tatttgatct ggtgttcctt
     7981 cttcttcagt gttgatttcc caaatgtaag cagaaggcac attatacgct ttcgagaaat
     8041 atttaaagca tccttcactt gtaacaatca tttttttatc attcggaatt gaagcaaatt
     8101 tagatttagc ttctttgtct agagaatcca atttttcaat atacttatct agattttctt
     8161 tatagaattt tttattatca ggatcttttt ccgctaactg tttttcaata tttttagcgt
     8221 aaataatacc gttttctaaa tttaaccaag catggggatc ttccttccct ttctcactct
     8281 gaccctctaa gtaaataaca tctatgccat cacttgctgc aaaatagtct ttgttttcct
     8341 ctttgttcgc attttttact aattttgtaa accaagcatt tcctccagtt tccaagttaa
     8401 caccgttata aaaaatcaaa tctgcttttg aagttttttg aacatcttca ggcaaaggtt
     8461 catattcgtg gggatctttc ccaataggta cgatactgtg taaatcaatt ttatcttttg
     8521 ctatattttc agtaatatct gctaaaatcg aattagtaac tactaccttt aatttttcgt
     8581 tcgaagccac tgtatctttg tctttactat ttgttgaaca tgccccgaat ataaaaagag
     8641 caatcaaaat ccccagactt cccagtactg ctttccattt tctcatcata actttctctc
     8701 cttctttctt aaaaattttt gttttggtga gattagaaaa ctaattacaa ataagaatgc
     8761 cgctgttaaa acaatacttg atcctgctgc tatgttaaaa ctataaccaa tgaacaaacc
     8821 tagcaatgat gagcacgctc cgactgtcgc cgaaataaat atcatagttt ttaaactgtt
     8881 tgcatataaa tatgctgtag cagctggtgt aattaacatt gcaacaatta atatagttcc
     8941 cacactttgc atagctgtta ctgctactaa agttaataga atcattaata gataatgata
     9001 aaaactgaca ttcatcccca ttgcttttgc cattaatgga tcaaaagaag tgattaataa
     9061 ttctttaaaa aatagaacaa ctgtaaccaa cactaaaaca gaaacgccaa ttgtaatcca
     9121 cttatcaata tcttgtacag ctaaaatatt tccaaataag atatgaaata aatccgttga
     9181 gctatttgca actcctataa ggataactcc taatgctaaa aaagaactga aagtaatacc
     9241 aattgctgta tctcctttta ttacactatt gctttttata aaagtaataa tgatagaagc
     9301 taatagacca aatacaatcg caccaataaa aaaattaata cctaaaatat aagaaattgc
     9361 tactcctggc aaaacagcat gagaaatagc atcacccata agagacattc ctcttaaaat
     9421 aataaaacaa cctactgttc cagaaacaat ccctataact acagatgtaa ttagagcatt
     9481 ctgtaaaaag tgaaagtcat acagaccatt aataaaattt tgaagcatat tattcccctt
     9541 gtatattaga gttagggttt taaccttccg gttttgattg gataacccta tgaaccatcg
     9601 ttattttaat ttggtattaa ctcatttctt ttgagataat atatttattg gattgagagg
     9661 ctaagcc
//
LOCUS       DACDLM010000094         9637 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.096, whole genome shotgun sequence.
ACCESSION   DACDLM010000094 DACDLM010000000
VERSION     DACDLM010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9637
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.096"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(162..3803)
                     /locus_tag="IV356_002549"
     CDS             complement(162..3803)
                     /locus_tag="IV356_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016174.1"
                     /translation="MKFKKYLLQNLRIKRWVVRGLVIGGVLAVTLGAPFGMNDPTPDN
                     QDSKQETVINKNVVYAESKPAEQGMWTLYARILMGDKEVNDSAAKTGQMNLLGQGGIS
                     ADFPYSDISKQGNSIAGGNAGTQLASTLATYSYYGYIETVSGNAIASQASSILGSIGR
                     TIGSFIGSISLILSNIAESINELLGKFFMSMNIFSLMGWGEGGSDVSNPVSKALTSLL
                     NNLGLNNELFKAIASLSMLFFTAILGYQGMKLLSKDGVNSKGLSPVLEKWIVRIFVLF
                     IFLPVAGSLLGVYINGIQSAKKDGDIPTNVVSDYIINTRLWASTQNLAPSSDTGGDVP
                     DGKPTSEIKFVDTDYEPSKKSAMIRAINTSSYARQNNDLDSNSVGMALLKEWSSNDTF
                     NINTYAGDVNVAENDAYMGRAPAVWTGYNLGDGKEGSAIKKPTNLNGYIWSANQNVTD
                     DNRKPDGKGTAHNFDATQPWGVANNATFSTQSVALLLQSALDTSGAKFYAYNIAPSGI
                     QGSAKNMSTVKTEWRTASLVGHGAMGKFGSWLAMNAESIVLAVLYLACAWAMFNVNIV
                     KAFKREFIRIWEVVLTGSLASGAGVMAISLGVVTTSLIGLQLPIFLITFIRAFGDTAV
                     GFIPNTLVGDGVANIVRSAMILGVGYLLVFKKGEKVNNLINMLIGLPLEVAFGFDERA
                     KLLFGNRNDAVRVVDGVSKAIKKSQGAKNPYYDGGNSSVKDMVAGGLGAVGAQKMAER
                     LNNMGDSNADAKSIADKVIPETPEGMSFNGGGVGSTINNTSFKDLVRQDQLRNNSQQY
                     IDHLGRMIDENGNFVDENGEILKDSKYGKDAKGNFIDEKGRLVDEDGNLIDTNGKPLE
                     DSEDGNIGMDSEGRLIDEKGRLVDEDGNLVDENGRRLLNGDFGQDSNGRLVDEKGRLV
                     DEDGNLVDEFGNKLGKHSDGYNVNGDLVDEDGNIIETRDALVADRNRELEQQRHTPIA
                     VAIPENEDDEITLDQTHQELRNEMSGEDVSDRVHRELGDGASGESQSRELNSNFDNSA
                     IRNDTALKDRESLTKETDKEQSDVKKKFIPTPNVNQTDKYETNIGSGMSKDNQSIREP
                     ELTNKNNRTNNSKSTSDNSGKSNQSTKKPSTAKSAVEYLSKTGKNVYTSADKALAKAP
                     KGSLAGITYEAKNEAIKIGKGTAKVAKATATGASKTGKVVKKSTMSVKDYIVKYGNQK
                     STENKSEDE"
     gene            complement(3806..5755)
                     /locus_tag="IV356_002550"
     CDS             complement(3806..5755)
                     /locus_tag="IV356_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HAP9016175.1"
                     /translation="MENSTEFFKNIQTEFNHALTPMKPPKHKLVGRDDELHELSLILN
                     RPETPQAILLGEAGTGKTALASEWAERQRQDGKKVQVYKLSIGQLRVGGDDVLQTRLE
                     TLIPRLKEYERILKSEDKENEFVLFIDEFHKVVSSFGSGNKIGGDSLKEPLANESLQL
                     ITATTRKEYENYIKRDDALGRRLQPLELNELKSDVVVDILRQWLNTSSVKDDPQASFK
                     LSQRIPDELLQEIVQANKLYREDLSEPAKSIAVMEDLIAKDRVDGNAYNRESLLQIFG
                     KYNIQLDSDFDMEKLQEELKSIKGQPLAVYTITMLFKRMKLGFDRFKGRKQPKATALF
                     TGSTGVGKTAMAKAVARGLYGDENKVLLVNMPDYKTKDDAMRFRRLIGTHVRHDPSAI
                     IVCDEYEKAGVETLDAFLSILDEGRISFTERGWDDREVHDTVSLSNTILFATTNAGAE
                     MFDSLNRYSSLSRVTNKENSNEYSTELKREYRKVASGIKQALIGEGLKPEVINRFGRI
                     VPFWALSEQTLLEIAYNEMLKSAELVRKHLNIDLRLPPRKERVYGQNFYADDLSMHLV
                     FDMASQEDSKSGGARNILHLVESEFEEAITEAIITYPNAKIFDVKLSEAGAFEGKGDS
                     NAEIIAKPSVAESKENKIVFSIGGA"
     gene            complement(5797..6855)
                     /locus_tag="IV356_002551"
     CDS             complement(5797..6855)
                     /locus_tag="IV356_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliS"
                     /protein_id="HAP9016176.1"
                     /translation="MKKNVNSTSTKDQYSIIGGLLGDKDKRTRHGLRIMLATFLGVLF
                     LLTGLGSYIYQLGNYNYYLVNNTTPIGSSLEFARSGAEITISDVWTDQNRDVTVVKLG
                     YSQNARKLLSTQGKNYNLYMATKEKDRPKKLEMSYGMLSTDGDAFLFLKGKLDERAYQ
                     VFIANQVSLISGDDTADDDTKVNVNEADSVTKALSQYSMNDVNNEGVISFGKKAKPVN
                     TPDNINFRINPYSDSTNVYQGSFLTKDGDIDYSKVVAVTSKNNVVNKLEDQLNASNTN
                     IKKIEATKAEYLERLQQNPDDKDSQESIRQLDSRMETEIKAINDTQKLIDQYKNADFN
                     KDSFGDMKTTFKYLTLTD"
     gene            complement(6974..7429)
                     /locus_tag="IV356_002552"
     CDS             complement(6974..7429)
                     /locus_tag="IV356_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016177.1"
                     /translation="MNAINWHEFVNYMESLLDDLKSFSIADAVKHGLPVSTTMKLRGL
                     KIPDEIIKLRTKTIIETAKVVDNMNHELKGKKTTYEKDFERFLKSVIGKYLGKKSFSE
                     LRDEEIVPTPMVSKIRKNKAEGNYYLGTIAKIIDYLENKEQKKGTKKGR"
     gene            complement(8012..8815)
                     /locus_tag="IV356_002553"
     CDS             complement(8012..8815)
                     /locus_tag="IV356_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAP9016178.1"
                     /translation="MSQEVTEKIIDSDVDLVSEQTNAIVRYNNGLNTTALRGFKPVEM
                     DVFWAILSKMKRQGTAEVTFDFNLFRYLVKYDRREKDSFYSVLKALSDKLGTLTYRFE
                     DSDVYEQLWLFQKFRIDKQKETVTIKANEEFEFILNSIGKNFTRFELDNFTKLRSSYT
                     KELYRHLMQYRNKEWRNGYWVVKVEDFRRALSIPSSYRMTNIDKRILEQAKEEFLAPD
                     ENGIQVFETFDYEKIYAKKGRRVDRLRFTFSEPESNLPTISMHNWLEED"
     gene            9462..>9637
                     /locus_tag="IV356_002554"
     CDS             9462..>9637
                     /locus_tag="IV356_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAP9016179.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LKQRDTVIIACVIWG"
BASE COUNT         2826 a         1974 c         1387 g         3450 t
ORIGIN      
        1 taccagcata agcccttttt aattatacaa ctttgaacag taaacattta attcatttat
       61 agacaattta aaataatttt tttgcataaa tagaaatttt ccttgacatc ttcagttaga
      121 aatcaaagta aaaagaagga gcaaatcaat gctccttctt tttactcgtc ttcagactta
      181 ttttcagttg atttttgatt accgtatttt acaatatagt ccttgactga catggtagat
      241 ttcttcacta ctttaccagt tttggatgct cctgtagcag tagccttggc aaccttagcc
      301 gttcctttac ctattttaat agcttcgttt ttagcttcat aggttatccc tgctagacta
      361 ccttttggag cttttgctaa agctttatct gctgaggtgt aaacattttt accagttttt
      421 gatagatatt caacggctga tttagctgtt gatggtttct tggttgattg attagatttc
      481 cctgaattat ctgaagtaga tttagaatta tttgttctat tatttttatt tgtcagttca
      541 ggttctctaa ttgattgatt gtctttcgac attcctgatc caatatttgt ttcatattta
      601 tctgtttgat taacattagg agtaggaatg aactttttct tcacatctga ttgttcttta
      661 tccgtttctt ttgttagcga ttctctgtct ttaagtgctg tgtcattccg aatagcacta
      721 ttatcaaagt tgctgttaag ctctcttgac tgactttcac cagatgctcc atctcctaat
      781 tcccgatgca ctctgtctga cacgtcctca ccactcattt cattcctcag ttcttgatga
      841 gtttgatcta aagtaatctc gtcatcttca ttctcaggaa ttgcaacagc aattggcgta
      901 tgccgttgtt gttcgagttc tctatttcga tctgccacaa gcgcatctct cgtctcaatg
      961 atattcccat cctcatcgac taaatctcca ttcacattat atccatcgct gtgtttacca
     1021 agtttattac caaactcatc aacaagattt ccatcttcat caactaaacg acctttttcg
     1081 tcaactaaac gtccgttact atcctgacca aaatcaccat ttagcaacct gcgtccattt
     1141 tcgtcaacaa gatttccatc ttcatcgact aagcgacctt tttcatcaat taaacgtcct
     1201 tcgctatcca taccaatatt accatcttca ctatcttcca atggtttacc attagtatct
     1261 ataaggtttc catcttcatc gaccaaacgc cctttttcgt caataaagtt gcctttagca
     1321 tctttaccgt atttactatc ttttaatatt tcaccatttt catcgacaaa gtttccgttt
     1381 tcatcaatca tacgtcctaa atgatcaata tattgttggg agttattacg tagttgatct
     1441 tgacgaacta aatctttgaa agaggtatta ttgattgttg aaccaactcc gccaccgttg
     1501 aatgacattc cttctggtgt ttcaggaatt actttatcag caatggactt agcatcagca
     1561 ttgctatctc ccatattgtt caaacgttca gccatttttt gcgctccaac tgctccaaga
     1621 cctcctgcaa ccatatcttt tactgagctg ttgccaccat cataataggg atttttagct
     1681 ccttggcttt tcttgattgc tttagaaacg ccgtccacaa ctcgcacagc atcatttcta
     1741 ttaccaaata ataacttagc acgttcatca aacccaaacg ctacttcaag tggtaagcca
     1801 ataagcatat taatcaaatt atttactttt tcgccttttt taaagactaa aagatatcct
     1861 acacctaaaa tcatagcaga tcgaacaata tttgctacgc catcgccaac taatgtatta
     1921 ggaatgaatc ccacagcagt atcaccaaat gcacgaataa aagtaatcag aaagataggt
     1981 aattgtagtc cgatcagaga tgttgtaaca acacctaatg aaattgccat cacacctgct
     2041 cctgatgcaa gtgatcctgt tagaactact tcccaaatcc gaataaattc acgtttaaat
     2101 gctttcacga tattcacatt gaacatcgcc caagcacatg ctaagtaaag aactgctaaa
     2161 acgattgatt cagcgttcat cgctagccac gagccaaact tacccatcgc tccatgacca
     2221 actaaggatg ctgtacgcca ttctgttttt actgttgaca tattcttagc actgccttga
     2281 attcctgaag gagcgatatt atacgcataa aacttagctc ctgatgtatc aagtgctgat
     2341 tggagcaata aagctaccga ctgtgtgcta aaagttgcat tgttagcaac gccccaaggt
     2401 tgagtagcat caaagttatg cgctgttcct tttccatcag gcttgcgatt gtcgtctgtc
     2461 acattttgat ttgctgacca aatatatcca tttaaattgg ttggtttctt aattgcactt
     2521 ccttcttttc catcccctaa attatagcct gtccaaacag caggcgctct tcccatataa
     2581 gcatcatttt cggcgacatt aacatcaccg gcataagtat taatattgaa agtatcattc
     2641 gatgaccatt cttttaatag agccataccg actgaattag aatctagatc attattttgt
     2701 ctggcataac tgctagtatt gatcgctctt atcattgcag attttttaga tggttcataa
     2761 tctgtatcaa cgaacttgat ttcggatgta ggctttccgt caggtacatc accaccagta
     2821 tcagatgatg gagcaagatt ttgagtagaa gcccaaagtc ttgtgttaat gatgtagtca
     2881 gaaacaacat ttgttggtat atctccatct ttttttgctg actggatgcc gttgatataa
     2941 actcccaata gcgatcctgc cactggtaag aatataaaca atacaaaaat acgaacaatc
     3001 catttttcaa gtactggtga taatcccttc gagttaacac catctttcga caataatttc
     3061 attccttgat aacctagtat tgctgtgaaa aagagcatag ataagcttgc tatcgcttta
     3121 aataattcat tatttaatcc caaattgtta agcaagctag ttaatgcttt agataccgga
     3181 ttagatacat ccgatccacc ttctccccac cccataagag aaaatatatt catactcatg
     3241 aaaaattttc caaggagttc atttatggat tcagcaatat tagaaaggat taaactaatt
     3301 gatccgataa aactaccaat cgtcctacca atacttccta gaatggatga tgcttgactg
     3361 gcaatagcat ttcctgagac tgtttcaata tatccgtagt aactataagt tgctaaagta
     3421 gatgctagtt gagtacctgc attaccccct gcaatcgaat taccttgttt agaaatgtca
     3481 gaataaggga aatcggcact gataccacct tgtcctaaca aattcatttg tccagtttta
     3541 gcggcactat cattaacttc tttatctccc attaggatac gagcatatag tgtccacatt
     3601 ccttgttctg ccggtttact ttccgcatat acaacgttct tatttataac tgtttcttgt
     3661 ttgctatctt gattgtcagg agttggatca ttcattccaa aaggagcgcc taaagtaact
     3721 gctaatactc ctccaataac tagacctctt acgacccatc gttttattct aaggttttgt
     3781 agtaaatatt tcttgaattt catagctacg cccctccaat cgaaaataca atcttgtttt
     3841 ctttactttc agcaacggaa ggctttgcaa taatttcagc attagaatca ccttttcctt
     3901 caaacgctcc ggcttcactc aacttaacat cgaatatttt tgcgtttgga taagtaatta
     3961 ttgcttcagt aatcgcttct tcaaactcag attcaactaa atgcaagata ttccttgcac
     4021 cccctgattt agaatcctct tgtgaagcca tgtcaaaaac taagtgcatg gagagatcgt
     4081 ctgcataaaa attttgacca tatactcttt ctttcctagg tggaagacgt aaatctatat
     4141 ttaaatgttt tcgtactaat tcagcactct tcaacatttc attataagca atttccagaa
     4201 gagtttgttc ggataaagcc caaaatggaa ctattcgtcc aaatcggtta ataacttcag
     4261 gctttagacc ttcaccaatc aaggcttgtt tgatccctga tgcgactttt cggtattctc
     4321 tttttagttc agtgctatat tcattagaat tttccttgtt tgtaacacga gatagtgagc
     4381 tatatctgtt taacgaatcg aacatctccg cacctgcatt tgttgtcgca aataaaattg
     4441 tatttgacaa tgaaacggtg tcgtgaactt ctcgatcatc ccatcctctt tcagtaaaac
     4501 ttatcctacc ttcatctaaa attgataaaa aggcatcgag tgtttctaca ccagctttct
     4561 catattcatc acacacaata atcgcagaag gatcatgcct tacatgagta cctatgagtc
     4621 gtctaaaacg cattgcatca tcttttgttt tgtagtccgg catattaact aagagaactt
     4681 tattttcatc gccataaagt cctcttgcca cggctttagc cattgcagtt ttaccgaccc
     4741 ctgttgatcc tgtaaacaga gcagttgctt ttggttgctt tcgaccttta aaacgatcaa
     4801 atccaagctt catacgttta aacaacattg ttatagtata aactgctaac ggttgccctt
     4861 ttatggactt taattcctct tgaagttttt ccatatcaaa atcagaatct agctgaatat
     4921 tatacttacc aaatatttgc aatagacttt ctcgattata agcatttccg tctactcgat
     4981 cttttgcaat caaatcctcc attacggcaa ttgatttagc cggttcggac aaatcctcac
     5041 gataaagctt gtttgcttgt acgatttctt gaagtaattc atcaggaatc ctttgcgata
     5101 atttaaaaga agcctgagga tcatctttaa cagaggatgt atttagccat tgtctcaaaa
     5161 tatcgacgac aacatcactt tttagttcat tcaattctaa cggttgtaac cgtctcccta
     5221 aggcatcatc tcttttgata tagttttcat attcttttct tgtagtagcg gtaatcaatt
     5281 gaagtgattc atttgctaac ggttctttta gcgaatcacc cccaatttta ttgccactac
     5341 caaaagagct aacaacttta tgaaactcgt caatgaagag gacaaattca ttttctttgt
     5401 cctcagattt taaaattcgc tcatattctt tcaatcttgg aattaatgtt tctaaacgtg
     5461 tttggaggac atcatctccc ccaacacgca attgtccgat tgataatttg tatacttgta
     5521 ctttctttcc atcttgtcgc tgtctttcag cccattcact tgcaagtgct gttttacctg
     5581 ttccggcttc acctaacaag atagcttgcg gtgtttccgg tctattcaag atcagtgaca
     5641 actcatggag ttcgtcatca cgtcccacta acttatgttt cggtggtttc attggtgtga
     5701 gagcatgatt aaattcagtt tgaatattct taaaaaactc ggtactattt tccatctgtt
     5761 tgtgttcact tcctctaaaa taagaataat ttacttctag tcagtcagag ttaggtactt
     5821 aaatgtcgtc ttcatgtctc caaaagaatc tttgttaaag tcagcatttt tgtattgatc
     5881 aatcaatttt tgtgtatcat tgattgcttt aatttcggtc tccattcgac tgtctagttg
     5941 acgaatactt tcttgcgaat ctttatcgtc aggattttgt tgtaaacgtt ccagatactc
     6001 agcttttgta gcttcaattt tcttgatgtt agtatttgaa gcatttaact gatcttctag
     6061 cttatttaca acattattct tacttgtaac tgctacaact tttgaataat caatatcgcc
     6121 atctttggta agaaagcttc cttgatagac attagttgaa tctgaatatg gatttattct
     6181 gaaattgata ttatcaggag tattaacagg ttttgctttt ttcccaaaag aaattactcc
     6241 ttcattatta acatcattca tagaatattg agaaagtgct tttgtaactg aatctgcttc
     6301 attcacattg actttggtat catcatcagc tgtatcatca ccagaaatta gtgatacttg
     6361 gtttgcaata aaaacttgat aagctctttc atctaattta ccttttagga ataagaaagc
     6421 atccccatca gtacttaaca ttccatagct catttcaagc ttcttaggac gatctttttc
     6481 ttttgttgcc atatataagt tgtagttttt tccttgcgta gataacaact ttctagcgtt
     6541 ttgcgagtaa ccgagtttta ctactgttac atctctgttt tgatctgtcc acacatctga
     6601 aatagtgatc tctgctcctg atcgagcaaa ctccaatgaa gagcctatag gtgttgtatt
     6661 gttcacgaga taataattat agtttcctaa ttgataaatg tagctaccca agcctgttaa
     6721 taaaaaaagc actcctagaa aagttgcaag cataatgcgt aatccgtgac gtgttctctt
     6781 atccttatca ccaagcaacc ctccaataat actgtattga tctttggtag atgttgaatt
     6841 gacgtttttt ttcattagtt tgtccgcccc ctttcataaa agagcaaaca atcagacgtt
     6901 ttttcggtaa ttctaggttc gggattttta atcatttcgg tatattcttc cccattaata
     6961 tttaacacaa aaattatctt cctttcttcg ttcctttctt ttgctcttta ttttccaaat
     7021 aatcaatgat ttttgctatt gtaccaagat agtaattccc ctcggctttg ttttttcgga
     7081 ttttgctaac cattggagta ggtacaatct cttcatctct caattcactg aaagattttt
     7141 tacctagata ttttccaata acagatttta aaaaacgttc aaaatctttc tcgtaagttg
     7201 ttttcttgcc ttttagttca tggttcatat tgtcaacgac ttttgcggtt tcaataattg
     7261 ttttagttct cagcttaata atttcatctg gaattttcaa tcctcgtaat ttcatcgttg
     7321 tactaactgg taacccatgc tttactgcat cagcaatact aaaacttttt agatcatcta
     7381 gtaagctctc catatagtta acaaattcat gccaattaat agcattcatt gtctcacccc
     7441 ttcatttttt taaaatgagg ttcgggcgta acacatttat gttattataa tatcataata
     7501 acataaataa atcaatcagc aaatttagat atcccttaaa gtatcagcaa ttattcaaca
     7561 agatatttat tttagctatt tcagtcatca tgaaagacta attagcaata aaataactaa
     7621 tattatccat ttatcagacg aaaagaaaaa acttatctaa ttactctata ttaactttta
     7681 acaaatagtt gacttgtcca aaaatgttac cttcaatctc acaaagatat taagatgttt
     7741 cctaccaaaa ctgatatcac cggacttttt attctgtgtt gtccaaaagt gttaccttta
     7801 gtcgatcaac aaattaaaaa aattgttttt ttcttgactt gtccaaaagt gttacccata
     7861 gttgttaaaa tttgtataga ttagccattc tttcaaatat tatttagact gaaacttgct
     7921 tacaaaaaaa cttcttgcat ttattgtcca aaagtgttac ccatactttt ttaaagaagc
     7981 aggttgtatt aaaattacaa cctgcttctt ctcaatcttc ttctaaccaa ttatgcattg
     8041 aaatggttgg caagtttgat tctggctcac taaaagtgaa tctgagccga tcaactcttc
     8101 ttcctttctt tgcatagatt ttttcataat caaaagtttc aaatacctgt attccgtttt
     8161 catcaggagc taaaaattct tctttcgcct gctctagtat tcttttgtca atatttgtca
     8221 ttctataact tgaaggtata cttaatgctc ttctaaaatc ttcaactttg actacccaat
     8281 aaccatttcg ccactcttta tttctgtatt gcatgagatg acgatacaat tcttttgtgt
     8341 agctacttct tagttttgta aaattatcaa gttcaaaacg agtaaaattt ttgccaattg
     8401 agtttaagat aaattcaaat tcctcatttg ccttaattgt aactgtttcc ttctgtttat
     8461 ctatccggaa tttttgaaaa agccacagct gttcatagac gtctgaatct tcaaaacggt
     8521 aggttaaagt acctagtttg tcactcaaag cttttaatac agaataaaaa ctgtcctttt
     8581 ctcttctgtc gtatttgacc aaataacgaa agaggttgaa atcaaaagtt acttctgctg
     8641 ttccttgacg tttcattttt gataaaatag cccaaaacac atccatttca acaggcttaa
     8701 atcctcgcaa agctgttgta ttcagaccat tgttataacg cacaattgca tttgtttgtt
     8761 ctgatactaa atctacatca ctatcaataa tcttttcggt aacttcttga gacattgatt
     8821 actctccaat cttctttttg cgctccttta atcatgttaa tctggtacta attaaaggaa
     8881 acattttttt ctgcttgtta cctaaattaa atcacaacta aaggtaacag tcaacaaaga
     8941 tttgttacta atctaatttt ctattttttc gccttccaaa tcaagaaaac cgaaggtaac
     9001 gtcttatcct agtatgatac ctcaaatgtc cacttttgtt acctttgctg tccaaaagtg
     9061 ttacccttac tgtccacttt tgttaccttt actgtccaaa agtgttacct ttatacccct
     9121 ttaatactta ctctcccaag agattaagcc tcccctaaca gatatattaa cagatattta
     9181 acagatatat taacagatat ttaataaagg aggattactc ctctcttatt tcaaaatctt
     9241 aaaaaaaaac taacactatc taggagttta ttttgcttgt gtaactttga ataattgaaa
     9301 aaaaggaaaa ggaggaagct tcagcttccc cttttattta tatttataat acccgtggtg
     9361 ctagttaatt ttttcctaga ggaaaatgtc taaacatgtt ggtaaatcaa caaaaaaacg
     9421 catatagtag tctcaaaact cccaagaaat gaggactaca tatgcgttca tcaaaatata
     9481 ctgaacatta tacagatact tttataacat tcaaggaaat tatgagaact gtttctaaca
     9541 tataccacaa ttgtgtacca gataagatta aaaaccgaag aaatactgat caactgaagc
     9601 aacgcgatac agtgattatt gcttgtgtta tatgggg
//
LOCUS       DACDLM010000095         9607 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.097, whole genome shotgun sequence.
ACCESSION   DACDLM010000095 DACDLM010000000
VERSION     DACDLM010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9607
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.097"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(180..887)
                     /locus_tag="IV356_002555"
     CDS             complement(180..887)
                     /locus_tag="IV356_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016180.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENG"
     gene            complement(952..1788)
                     /locus_tag="IV356_002556"
     CDS             complement(952..1788)
                     /locus_tag="IV356_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP9016181.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(1806..3215)
                     /locus_tag="IV356_002557"
     CDS             complement(1806..3215)
                     /locus_tag="IV356_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP9016182.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(3229..5052)
                     /locus_tag="IV356_002558"
     CDS             complement(3229..5052)
                     /locus_tag="IV356_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP9016183.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
     gene            complement(5895..6221)
                     /locus_tag="IV356_002559"
     CDS             complement(5895..6221)
                     /locus_tag="IV356_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016184.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
     gene            complement(6267..6629)
                     /locus_tag="IV356_002560"
     CDS             complement(6267..6629)
                     /locus_tag="IV356_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HAP9016185.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEKMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(6666..6881)
                     /locus_tag="IV356_002561"
     CDS             complement(6666..6881)
                     /locus_tag="IV356_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP9016186.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPMNELFSDVFNKVNS"
     gene            7008..7343
                     /locus_tag="IV356_002562"
     CDS             7008..7343
                     /locus_tag="IV356_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP9016187.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(7419..9416)
                     /locus_tag="IV356_002563"
     CDS             complement(7419..9416)
                     /locus_tag="IV356_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016188.1"
                     /translation="METSMINIPIYVDQEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKIHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVGDNSVKNALIKNRGYFVKQGFTLERASKDIKKLYNVKASSSFLIYLAKGAGI
                     DETIKELILSGAGIVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(9514..>9607)
                     /locus_tag="IV356_002564"
     CDS             complement(9514..>9607)
                     /locus_tag="IV356_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAP9016189.1"
                     /translation="SQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
BASE COUNT         2958 a         2007 c         1435 g         3207 t
ORIGIN      
        1 gaaaaaaaat acccccagta gcttatccta agctactgga gatgtataag tacggtcata
       61 taacaacggg gtagggtaaa taaatgaaaa agatggaaga atcattattc aataactttt
      121 ttaaatactt cgttgtaatc agttacctgt ccgttcttaa ataccacaga ataatctttt
      181 tacccatttt caagtaaccg aagtggaatg tctttaccaa cttgctctgt cactgcatta
      241 ctgatacctg ttagattagc taataaatct gataaagatt gagcatctgt agaaatctct
      301 gtatcagtat ttatcgtgat tcctttatct tcatttacaa gcttccaagt aggtggtata
      361 gctgtgtatg tttcgatgaa tgaatcaatt ctttcatcta tcgtcttccc agtatctact
      421 tctgtctcat tactcttaga tgaatcgatt ctttcatcca tcgtctgctc cgtaactgct
      481 tctgtctcat tattctcacc ggaaactctc ttcacaccca aacttatata ttgtccatct
      541 ttagtgtgca tagttaaaat tcccacgctt ttactaataa attcactata accagttctt
      601 tcaatagaga cttcaatgta tttcacacta tcatactcaa aagaaaaata gacatgtaaa
      661 agcattttgt tgtttacatc tacataataa tcctttgact ctacttgaga ccttcctata
      721 cggaatacag ctttactgtc tgatatctct ataccagcat ccttattatt aatctgccaa
      781 tctccaagta gctcttctgg caagctagta gtttcttgtg aacactttac cacttcactg
      841 gtagaggtcg aaacattcac ctccgcactg ttagaagaat tttccaagga atcaggagcc
      901 ttagcacaac caacaagtct ttatatattg tgcagccgat attttcttca ttcagtacac
      961 ccttgaaata tgcagtgtta gataaagcag ttcgtcctga tttgctgagg cacccatctc
     1021 ttcttgaacg tactccttga ttttcaaggc cgcccgatac tctttcggaa aacgctgctt
     1081 cactgaagcc agcaaaaaat catccttctc cggcaactct tccttcttaa tcattcgggc
     1141 aataaaaaac tgtaaatgcg tcacaaatct taagtaaagc atcgaatctt tatcaacctt
     1201 tttttcggga aacagatatc ctagcatagc caagatatcc tttagtgctc ttaccgagag
     1261 catggtttct tccatatttg cttgttcact ttgggcattt acaatgtgaa acgcaatgtt
     1321 tccagcctcc tcttctggca actgaacatt catttttttg ttgatcaatt ggatagcata
     1381 gcagccgatc tcaaattctt ttgggtaata cttttgaatt tcaatcagca ggcgattttg
     1441 aaaaacaatg cctttttgac tgcgttcaat ggcatgcttc aagtgatcaa ccaaggtaaa
     1501 aaatagactt ttattcagct taaagtcaaa cttggcgttg gcataatcga taattcgctt
     1561 gacgcaaata attagatcat ccggagcagc ctcaaacagt ttaatgtaat ccttttttag
     1621 agcatcagaa agtgaatcta atttaaatac tttttggatt ttgtcagccg gaaccaaatc
     1681 gcctttcttt agttgaaatc caatcccttt ccccatcaaa attacttctt tgccttgctt
     1741 atctaagcaa agaattaaac tgttgtttaa cgttttaatt actctcatta gattcaccgt
     1801 tctctctaag ctaagccatt tcttgcgatt actttttgat accaaaagaa gctttctttt
     1861 tttattcgtt ttaattcttt aagattctca tcggttcggt caacatatat aaaaccataa
     1921 cgcttattga agccttgatg ggtactaaca acatcaatcg ctgaccaagg taaataacca
     1981 aaaacatcta caccatctgt taaagctgct tgaatagcca gaatatgttt ggctagataa
     2041 tcaattcgat cctggtcatt aattcgtcta tcttcctcaa ctatgtcggg tgccccatag
     2101 ccattttcag taattaaaat aggtaaatca tagcgatcgt acaatttcct caatgttaat
     2161 cgtagtccag tagggtcaac tacccagcca tatggcgttt tatctacata aggattttca
     2221 gctgcccggt agacaccttc ttctcccaac atgatctgtt gatcccccgc tctagcggaa
     2281 acatctgatc cgtcattttt gctggcagcg atggtggcag ttgaataata attaatcgca
     2341 ataaaatcgg gtttaccgga ggataaaatt gcctgatcct ctgcctcaat tttaggatat
     2401 aatccacgat cattcaaata gttttcaaac aaataattgt attttccccg aactgctaca
     2461 tctaagaaag accagcctct caatgtttcc caattatggg ctgcaattgc atcttctgga
     2521 ctggaggtag cttgatacat agccgttaaa ttgattgctg gaccgatttt tcctttaaga
     2581 ttcaactgat gatacaagtg aattactcta gcttgagcta ataaaacatg gtgattaatt
     2641 tgaaagagtt ctttttttga aggcagctct ccacttggtg gcaaaccaat cgctccagga
     2701 tgaaggatca tcgtgttttg ctcattaatt gtcagccaat agttcacctt gtcaccatac
     2761 tcagtaagca atacctgtac atagtccaca aaataatcga tagttgctcg atttaaccaa
     2821 ccgccctgct cctctagaaa ataaggtaaa tcgaaatggt acatggtgac aatcggttcg
     2881 attccctgat tcaggcattc atcaattact tgatgataaa aagaaattcc cttttgattg
     2941 gttttattat tttcaatatc cataattcgc gtccaagcga tggaaaagcg aaaagctttt
     3001 aagcctaatt ctttaaacag ctgtatatct tctttatagt gatggtaaaa atccgaggca
     3061 acttcaaaat tagctacccc ttctgtatgc tgatacttgt caataataga cggttgtttc
     3121 ccatcctcct gataggcacc ctctgcctgg taggcactaa tggaggcacc ccataaaaac
     3181 ttctctggaa atgctgaaag ctgtttgtat tgcacaaaaa tcctctcctt aactaatttg
     3241 catcaatggt tcgtgttcct ttaagcttcc gcttgcttca ctaattcctg cgtaattttc
     3301 actgttggtc actaccacaa tcactgtatc atcgtagcca gcgtttctaa tggcagcgaa
     3361 atcggcgttg attaataatt gtcctgctga cacctgatct cctgctttta caaatacttc
     3421 aaagggttcc ccttttaaat tcacggtgtc gatccccaca tggatcaata attcaatacc
     3481 ttctttagaa cgtagaccaa tcgcatgttt agattctaaa atagtaatga cttctccctc
     3541 aacaggtgaa taaatgctgt tttcttctgg atgaatggct acgccctttc ccaatagtcc
     3601 cttagaaaag acagcatcgt tcacttcaga aataggacac acggttcctt ttaccggatt
     3661 ttcaacaatg actgcttcgg ctattgccgt ttgctctgat tcatcagaag tatcgtcaaa
     3721 tccaattaga taagcaatga taaaggttgc aacaaaggcg attacacacg taataattgc
     3781 gtgaacaata ttcattggat tttctccaat aaaggctggt aaggctgcta agccagggga
     3841 aacaaaggca tatctgacta aaccgctcaa gccagcatac aaaccagcaa ttgcaccacc
     3901 aatcatggaa gcaactaatg gttttttcag cttcaaggtt actccataga gtgaaggctc
     3961 agtaattccc attaaagcag tgatcccagt ggacacagct agctgcttca actctttgtt
     4021 tttagttttc gcggctacag caaaggtagc acctgattga gcaatattag aagccagcat
     4081 tcctggccca ttgatcattt cagaacccgt actgctcaat tgcatagtag cgattggcgt
     4141 cattgcccaa gctgtacccg taaccaccaa aaatggctgc aaaccaccca tcaaaaatgg
     4201 aattaaccaa gctgctttgc cgttaatcca ttcagccccc attgctataa gatcgttcag
     4261 caacgttcca aacggtccaa tgacaaccaa cgctaaaggc cccataatta aaaataccag
     4321 catcggctta gtaaagaatt taataaacga aggcgaaatt cgatccgcaa agggctctac
     4381 ataggacatg atccaaacag taaagataat cggtaaaact gatcccgcat aatctgcagc
     4441 taataccgga attcctagaa aagaaacggc atcgccagta gaaaaaagct gtgaaatatt
     4501 tggatgaagc aaaatgccag caacagtaat cgccaaaatt gggttgacat caaactttat
     4561 ggctgcccca taggctaata gtactggcat aaaataaaag gctgcatcag caatagtatt
     4621 caaaatgatg taagtttgac tactgtctga tagtacacca gtcaaagtca agacggccaa
     4681 aatggctttt accatcccgg cacctgttat agctggaatc atcggtgtaa aggtggtaga
     4741 aatgacacta atcaatcttg aaataatact ttcttgattg tctgaagagg ggcccttttt
     4801 aattgaagtt cccacttcct tttgaatttc cttgaaggct gtttggactt cattgccaat
     4861 caccacttgg tattgtccac cgctatccac cacactaatt acaccaagtg ttttttctaa
     4921 ggctttcgta tcggctttcc ttttatcttt gagttcaaaa cgcagtctgg tggcacaatg
     4981 ggttaagctg accacatttt cttttccccc aacctgttgc aatacatttc ttcctacttc
     5041 tctgtaatcc attattctct ctccttaaag cagtaaaaaa gaccaagtca aaccacgccc
     5101 caatcaacat tgaagtgtta gtttgtcttg gtcttgcctg cataatcagt aacatgccaa
     5161 taacgttatt ttgctgtaat ccaataatag cacattatga tagcgcaatc aacagggaat
     5221 ttaatttttt atcttttcgt ttgaccgtat agggtaatat aacagttaga tcacatcaac
     5281 tagggtatat ctgcgtatac ttactgctaa aataagtata tctaatatta actataccag
     5341 taaaaccatt cctacataac cagcgggaaa ttcccaaaat cgtgaaagca tcaaaaatgc
     5401 atataacgga tcacacaact tcaacaattc tgctcttggg aaaaattgat gaatttggtg
     5461 agtaaaggat ggaataaaca gcattccaac aatataggca acaatagtga tacttgtttt
     5521 tttggtaaaa atcagtaagc aatagccaat ttcaatcatt ccgagatata aaggtatcaa
     5581 tagaatgatt tgggctagta ttcttaaaaa ttaactagca aatgtttaaa ctgatttatt
     5641 tctaatctac atgtagtaag tatttcaatt ccaccaatta tcaataaaaa taccaaacat
     5701 atccataata attttttctt tttcatttct tttatattgt tataacagtg aataacataa
     5761 aaattcccga caatcattgt aatatttttt tgtcacctgt attagtattt aatttatagg
     5821 aaactataaa aactccctag tgaatttaca cctttgggag ttcctgtttg gacggtatgc
     5881 ataatacatt taaatcaatt taacattaac acctcagcat atggtatctc cacatatata
     5941 cggtctttct ttggatagta ctcaatattt atgttgatag cacttccatt gtctaatata
     6001 gctttagccc ggtatgtgtt atctccattt tcatgagtaa tcgtcacatc atcacatgat
     6061 cgatttaagt tgtactgttc ttgtaaaatc tgtgttacca atggttttga tgacttctct
     6121 aatccagatg tacctgtcat ttttgaaaaa ataataccta taatagccaa gacaacaata
     6181 cctataatga caaacttctt gttcatattt actttattca actttttatc tcctatctcc
     6241 aaaataattt gttcttatcc ctcttatcag tacattgaca tccctaaaag tacaccaaag
     6301 attgctccag ctacccctgc tatcatcaaa atcgtaccca ttttctcatc tttttctcga
     6361 tataagtagc ccataataac agcaacagca ccaaatacaa caggaataaa tgctaacgat
     6421 actaccatag aaatccaacc aataatcaaa tacagcttcc ctgtctcttg tccatgtacg
     6481 atttgttcct tcatttcatt aattgtctgc tcagtacttt tctttactgt gtctgttccg
     6541 gttgtctcat ctgtttcttg tagtgctcca caaaactggc aatacttact ttcatctgtt
     6601 atttctttgc cacattttct acaatacatg tcttctcctc ctaaaatcat tcaattgctt
     6661 attagttaac tgtttacttt attaaataca tcagaaaaca gctcattcat tggtacactt
     6721 aatatctcag aaagcatctt catttgatag ggtttaggaa tcgttctccc tgtttgccac
     6781 gaacttacac attgctgtgt aacattcatt ttttttgcta actccgtttg agaaagtcct
     6841 ttttcttttc tgtatcggct gagattactt acttttttca tgattctccc ctcctgtttt
     6901 attatataca acaatatgat gtatttcaac tcataaaata taaaaaactt caaataccat
     6961 tacaaataca acaacttgtt gtactatact gagatggggg tgtattaatg aaacagaaac
     7021 aatatgcaaa ggtcattaga gaaaagcgaa aagctctcgg gtggacacaa aaagaattag
     7081 ctgaaaaaat cttctctaca caacaggcag tagcaagatg ggaaaattct gtaacagagc
     7141 ctaacctcga tagcttaaca gctctttcta gagccctagg aacccctgta agccattttc
     7201 tagacaatgt tgtcgtagat tatgaggaag agtttttggc tctctatcgt tctcttagca
     7261 ctgaagatgc agttcgaaca attgactata tgaagctatt aaaaaggcaa gaaaatgaac
     7321 gcaatcagct attgaaagat tgaaaaataa ataacccacc gaactttaac ggtgggtgta
     7381 ttgagatgaa ataagattaa gagctatgga taacctgtct agtttaatac aattgggtct
     7441 tttctcttcc ttactctccg tccatcatct cttgttacac ttgtaaattg atacagagga
     7501 actatcccag ctcctgataa tatcaattct tttattgttt catctatccc tgcccctttc
     7561 gctaaatata ttaaaaaact actacttgct ttcacattgt atagtttctt aatatcctta
     7621 gaagctcgtt caagagtgaa tccttgttta acaaagtagc ctctgttttt tattaaagca
     7681 tttttcacgc tgttatcccc aacattacgt aggcgttcac aaacagtgtt aataagttct
     7741 ttctctgtca ttagatatgt cccttgccac gataagccct gtaaaacttc atgtgcttca
     7801 tctaaaatca attgtttttc cttgctgagt tctgatcggg aattttgagg aaatactctt
     7861 ttagcctctt tttcgttaaa acatatctta acccattcat aagaaaaata ttgatatgta
     7921 aaatgaattt tttccagaag tggaaggata tcttcattca atttttgaat cacagaagtt
     7981 gcattaaaaa cgtctaatcg atagacattg cttctcttat gattaaagtt tcctaacgct
     8041 ttctcttcct ttaacctatt taggtattcg agcatcttca aaggaacatc ttcatcatct
     8101 aattttttta tcaatcctat aaaagtcata agtgatagta acttattaca tttatctatg
     8161 tcataagttt taccatagta agaactcatt tttttagcta attgttcccc cgacaaaata
     8221 caagtcacac tttccttact atcatcaaaa aaattaacat cagaaagcaa gacatcatag
     8281 acacgtcgca tttcctctag ataattcctt attgtcctga aaagtttgtc tttcattgat
     8341 tcaagagtgt caaaaagtac ttttgattcc tctttcaatt ttcgaaaatg tgtaggatac
     8401 aagtctaggt tctctaatag ccaattaaat gtttctaccc gactgtcttt ctttaaaatt
     8461 agcatcacaa ctccaataaa attttcactg atatcacaat tactggaatg acaataaaaa
     8521 atggaatgcc cagttttact ggtaaaaata ctagcagagg gattatgatc gttgtgaaac
     8581 agacatctta agtttttact tgacttaagt aatttattca tatcaatggt taacaatctt
     8641 tcataaatct cattaaaaga catgtcggag gaatcaaaca ggcagtcttt aaaccactgt
     8701 ttcatttctt ctttgtcgtc attttttatc aacttaacaa aatcggtttc attgactagt
     8761 tcatactctc tccctgaatc actttgacaa tttttagaac atgtcatggt aaaatcaatc
     8821 ggaagctcag taatatctaa catgttgtct tcattaatta ttatcactgc atctgactta
     8881 tatcctccaa aaaacattct attcgaagca tttacattgt catcacaccc ggggatgttc
     8941 tttttcaagt attcgtaaac agcaaccatt ttaccatagt cagtaattgc ttcttttaat
     9001 agaaagacaa tcttgtattt ttctagattt tcagagtacc gaatactttt ttgtatcgca
     9061 aacgcagaat tatgaactaa attgatagat aaaacctttt ctatgcttaa gtatctacta
     9121 tcatctttac tcaaatctac taccttcccc ttctcatctt taacagtgtt atcgacatcc
     9181 agaataatta ctctggtttc cacaaaactc tccttgtcat tgcctttatt ctttgtcttg
     9241 cttggaataa atgattgtga tgaatttagt atctctacaa actcatctct tgtaacttct
     9301 ctatagttat ctaaacacct atctcttaca tcagtttttt ctttttttgt aactggcttc
     9361 tctaataatt tttcttgatc tacataaatt ggaatattaa tcattgatgt ttccatttgt
     9421 gtttcctcct tataaaattc tgttaaagac taaaacatac agataataaa aacaaactct
     9481 ttattactat atgttttagt cttatttgtt tactcaacct ttataccgtt ccatgaaact
     9541 atcaatatca gattttttaa atctaatgac cgtatcaatt tttataacag gtaacccgta
     9601 ttgagaa
//
LOCUS       DACDLM010000096         9488 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.098, whole genome shotgun sequence.
ACCESSION   DACDLM010000096 DACDLM010000000
VERSION     DACDLM010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9488
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.098"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            125..1429
                     /locus_tag="IV356_002565"
     CDS             125..1429
                     /locus_tag="IV356_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAP9016190.1"
                     /translation="MLNDINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLS
                     QNSLFLKTCLLYLEEDEPDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPR
                     FTEMERRLLLLNVSYRLGGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILLI
                     GFAISFLRQQVCAVTIDSKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLF
                     NLCNYGFHSYQLIAEDFQQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIH
                     LMRSAWDNYQLFMPEKFYLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVI
                     ELSGILRLTKEHLTIYIVTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQ
                     QSSNRVLCERTLYTPDAVQYENIIPISINTIDRAIISAVQNK"
     gene            complement(1521..1886)
                     /locus_tag="IV356_002566"
     CDS             complement(1521..1886)
                     /locus_tag="IV356_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAP9016191.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(1883..2248)
                     /locus_tag="IV356_002567"
     CDS             complement(1883..2248)
                     /locus_tag="IV356_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAP9016192.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2440..2688)
                     /locus_tag="IV356_002568"
     CDS             complement(2440..2688)
                     /locus_tag="IV356_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016193.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2687..2815
                     /locus_tag="IV356_002569"
     CDS             2687..2815
                     /locus_tag="IV356_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HAP9016194.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            2872..4566
                     /locus_tag="IV356_002570"
     CDS             2872..4566
                     /locus_tag="IV356_002570"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HAP9016195.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKMTNTLTQ
                     EEEHVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4648..4839
                     /locus_tag="IV356_002571"
     CDS             4648..4839
                     /locus_tag="IV356_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016196.1"
                     /translation="MDLLPQMQAFEHRLPRGCEKAALHQVIRAAKLKQLLMFLTWLDL
                     LPQMQAFEHRLPRGYEKVV"
     gene            5217..6350
                     /locus_tag="IV356_002572"
     CDS             5217..6350
                     /locus_tag="IV356_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HAP9016197.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQNGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYE
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            6381..6701
                     /locus_tag="IV356_002573"
     CDS             6381..6701
                     /locus_tag="IV356_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016198.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(6730..7194)
                     /locus_tag="IV356_002574"
     CDS             complement(6730..7194)
                     /locus_tag="IV356_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP9016199.1"
                     /translation="MVTYNWIKLREHPELVKQSAKWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(7323..8572)
                     /locus_tag="IV356_002575"
                     /pseudo
     CDS             complement(7323..8572)
                     /locus_tag="IV356_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736485.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(8601..8918)
                     /locus_tag="IV356_002576"
     CDS             complement(8601..8918)
                     /locus_tag="IV356_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAP9016200.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(8944..9264)
                     /locus_tag="IV356_002577"
     CDS             complement(8944..9264)
                     /locus_tag="IV356_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP9016201.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDIINMADYGMMNGEKVLDQAEK
                     LINK"
BASE COUNT         3055 a         1870 c         1691 g         2872 t
ORIGIN      
        1 ccccttttaa ttagatttct agtctaactt ttggggtgca catcatttat gtgggcaatt
       61 ctatgtaaat aaagaagtca atctagaaaa gctctccaat ctcctgcatg tttgcaaaac
      121 cactttgctc aatgatatca ataacataaa aaaagaattt gaagaacaga tcgcttatac
      181 acatcgggaa aaggaccgtt acactttata tttttcagaa catatacctc gatgcaagat
      241 catgcagcaa ttgtctcaaa attcgttgtt tttaaaaact tgtctgcttt atttggaaga
      301 agatgaacct gattatcttc aattaactga atgtgaattc atctctgtca gcaaagctta
      361 ttcattaaaa aaacaagtat tagcttattt taatgactgc gggatcgaaa tcgaccgcta
      421 ctcccctcga ttcactgaaa tggaaagacg tctgctgctt cttaatgtgt cgtatcgttt
      481 aggcggtttt aattcttggg agctacctga atcgtttttt gaacgtgccg atcgtttcat
      541 tgaatccgta acggaaaata gtggcagatt ttatgataaa gaaaataaag aaatcttatt
      601 gattggtttt gctatcagtt tcctacgcca gcaagtgtgt gctgtgacaa tagattcaaa
      661 atttatcgaa gaaatcaaaa aacgtcctat ttacaattat gtcgaatcag catgggaaaa
      721 cactgatttc caaacctatt ataaaaaaga agaattcgcc tttattttga cactattcaa
      781 tctttgtaat tatggtttcc attcttatca gttgattgcg gaagactttc aacagctaca
      841 ccaagtgttt attgacaata ctcccgaaat aaaagaacta gttgctacct ttgaatctca
      901 cttcaatcaa gaattattcg gaaaccaacc attcgaacgt gcgctgattc atctgatgcg
      961 ttcggcttgg gataactatc aattattcat gccagaaaaa ttttatcttc taaatgagga
     1021 acagacaaat ttatataaag aagtccagac aattttttcc agctggtcca gccagttacc
     1081 ttatgatcta cggttgaatc ctaattgcat gcgggctttt gtgatcgaat tgagcggaat
     1141 tctccgtctg acaaaagaac atctgactat ctatatcgtc acaaattcgg atgttcatta
     1201 tctgatttat cgggaagcct tggaagctgt aactactttc gattttcaag ttgcaccaac
     1261 aatttattca agtatatctg atataaagaa gtatgcgcag cagtcctcaa accgggtatt
     1321 atgtgaacgt acattatata caccagatgc ggtccaatat gaaaatatta ttcctatttc
     1381 gatcaatacg atcgatcgag ctatcatttc agctgtgcaa aacaaataag ggactgtgac
     1441 aaaaatcatg tcacagcctc ttatttgttg aagatgccca tttctgtaac aatctcttga
     1501 tacacatcag gctcacaacc tcacttattt tggacatcta cgggtccgat ctctttattt
     1561 aaaaaataag aaatgatggt tcggataact accaacgccg ctagttggaa aatatcctgc
     1621 aaggtaggtt tgataatcga ttcgatgatc ccagctgaaa caagaatttc caaacttaga
     1681 agtatatagc ctcccaacat ctttttaata gcattgttct cgctgactcg gtcgctttgc
     1741 acttttgtat ggacaaataa atatttcaaa aaatccttga ttgatagaca aacaccccaa
     1801 accaataaac agatagcaaa gatatcaagt cccagtacaa gtttttcaaa atatggaaga
     1861 agaaactgca tcaactctgt cgtcatccta cctctcctct tctttgtttt tctttgtctt
     1921 ctatttcctg attcaagaaa taagaaatga ctgttcgaat gataataata agtgcaagct
     1981 tcaaaatatc tgtccaagtc ggcttgataa ctgactcgat gatatcagca acgactagta
     2041 cttccaagct taacaaaata taacttgcta gcagttttct tgtatctgca ttacgagtat
     2101 tacgttctgc atagtttttc ttgacatgag accaatcaaa aagtttgaat agaacaagaa
     2161 cgatcccgac aattaagata ccgatagaac aaatatttaa aatagcaatg atccattcta
     2221 gaaattcaat taaatttgag cgaaacatat acgctaccta ctttctttta atttgttcct
     2281 attcttttat tgtaaaagaa agttaccttg ttcgtctatt taaaagttgt tctaatgata
     2341 acggttcgct taaatttttc tttttcactc tccccttttt ctccctccat ccataaatcg
     2401 tggaagtatc caaaacaacg tagcaagtta aaataaggct tagtccgtca tcagcttttc
     2461 aaagaagcac tgtctcggtg ctttttttgt acccaaattt ctaaaaatag aaccatacac
     2521 ctcctcaaat cttttcttct tacctaccct atttttattt acaggaaaat cagacacttc
     2581 ttcttttttg tcaaaatttc ctttttcttc tcgtcctatc atttggcatt ctaataaaaa
     2641 cgaactatcc ttggatatag aaagagaaaa caaggaggcg tttttcatga gtaaaaaatt
     2701 aatcaaagtc ggcatcggtt taggtttgct tgcccttggc gctgcatatc taggaaaaaa
     2761 gacaggacta ttcgaagatg acagtcattt atatgatgaa ttcgaatcaa tctagcatcc
     2821 tatttagttg aatcactacg gacatacttg gaagacattg gaggaatcac aatgagaaaa
     2881 agtaaagcaa taatgattgg tgccggtatt gccaatatgg cagcggctgt ttatttgatt
     2941 caagaaggca aatggaaagg ggatcagatc accttttatt cattggatga tcacggttca
     3001 aatgatggtg caccgaccga cactgtagtg gatgaatatt ggaataaaaa ccatccatta
     3061 gaaaaccaaa aaggctatat tgctcgaggc ggtcgcatgc ttaattaccg tacctatgta
     3121 gatttgatgg atctgttaag tcgaatacct tctgttactg agccagggat gactgctgaa
     3181 gaagatacga gagattttga tgcaaaacac cgaacctttg acaaagcacg tttgatggaa
     3241 ggtggcaaag gaatcattga tggcggaaaa ctgggattca ataataaaga ccgtattctt
     3301 ctgactaaac tgattgctat gcctgattca gaagaagaaa aactagacaa tatcactatc
     3361 gaagaatatt tcaaagatga tccacacttt tttgaaacaa acttctggtt tatgtgggaa
     3421 acaacatttg ctttcagaac acgtagttct gctcaagaat tgcgtcgcta tatgcatcaa
     3481 atgatttatg aattcactca aatcgaacat ctagtgggcg tcaatcgaac acgttacaat
     3541 caatacgaaa gtattatgct tcctttgatc gagtacttga aagaacaagg atgcaaaatc
     3601 attttgaacc gccgtgtcac tgactgggaa ttcaaagaaa caccgatgca agatgaaatc
     3661 actgtgactg gtttgaaaat gaccaataca ctgactcaag aagaagaaca cgttgtggtc
     3721 gatgaagata cagcagttat tttcactaat gggtccatta cagattcagc tactttagga
     3781 gattacgaaa caccagctgt agaaaatatg gattatggtg cagcttctag tctctggaaa
     3841 aaagccagtg aacgtttcta caacttggga aatcctgaca aattctttgc tgatcgagat
     3901 gcaagcgaat gggtcagctt taccctgacg acgaaaaacc atttgttgtt gaatgaaatc
     3961 acccgtatca cgactcaaga accaggaaat gccttgaatt catttatttc aaccacaccg
     4021 atcacgccgt taggccaaaa agatgtcaat atgtctatcg tcgtgcatca tcaaccgcat
     4081 tttacgtctc agaaaccaaa tgaaacagtt atttggggtt atttccttta tccaagacga
     4141 cgtggcgaat ttgtggataa acagtatatt aaaatgaatg gaaaagaaat gctagaagaa
     4201 ctgattggac aactttcaaa agtagatcct ggaccagtga atattcgtga aaaagaaaca
     4261 gaaattttcg acagcgtaat aaataatatc cctgtctata tgccttatgc ttccgcgttg
     4321 ttcaataatc gtgccaaaag cgatcgacca aaagtcattc ctaaacattc gaccaatctg
     4381 gcctttacag gagaatttgt cgagcagcct tatcagatga tctttactga acaaagtgct
     4441 gtacgttctg gagaaatcgc tgctttccat tttgcgggta tccctatgtc acgtcttgtc
     4501 aaaacaccgc gttacgacaa agatattcct actctagctc gtgccgcaaa aaaaatgttt
     4561 gaataatcaa gaggttgtga aaaagctgcc ctgcatcaag taataagaac aaccaggcta
     4621 aaacagcttc ttatgttttt gatttggttg gacttattac cgcagatgca agcttttgaa
     4681 caccgtttac caagaggttg tgaaaaagct gccctgcatc aagtaataag agcagccaag
     4741 ctaaaacagc ttcttatgtt tttgacttgg ttggacttat taccgcagat gcaagctttt
     4801 gaacaccgtt taccaagagg ttatgaaaaa gtcgtttagt ttcgagtatg aagaaaaatt
     4861 ttgtgaaaat ggttcctcac gtttttgcat aaatttgact taataccgag aaactgatcc
     4921 cttctgtcat aacctctttt tatttatgtc tgtttctttt tgaaaacaac cattttttca
     4981 acgtttactc tcttgccaat ccaacatcat ctaacagata caactatttc aatgattacc
     5041 attacactaa aaaatcggaa actcacctct ccgaacacaa atacataaga ctatagaatg
     5101 tttcatttaa gaaaaaaagc gtttcattat caaaaaggta agatctcctt taaaatgaaa
     5161 ttatctgtag tactaataat gcagacaatt ttatgaatct gaaaggagca tctccaatga
     5221 aagcagtcac ttggcaagga aaacagaaaa tggaaatcag aaacgtagat gatccaaaaa
     5281 tattagaacc aacagatgca atcatccgta tcacagcaac agccatttgc ggctccgatc
     5341 tgcatcttta ccatcatggt gaagcagttt tggaaaaagg gtatgttgta ggacacgaac
     5401 caatgggaat cgttgaagaa gtgggatctc aagttcaaac attgaaaaaa gggcaacgtg
     5461 tggttatccc ttttaatatt agttgtggtc attgtcattt ctgcctgaat cacatggaaa
     5521 gccaatgtga tgaatcaaat ccagatcagt tatatggcgg gcttttcgga tttggcaagt
     5581 tgaacggtaa tcattggggt ggtcaagcgg aatatctaag agttccttat gcagactcta
     5641 cttcatttgt tgtaccagat aatgatcttc ctgatgaaaa agttttattt ctatcagata
     5701 ttttgcccac agcttattgg agcgttgaaa acgcaggagt aaaaaaaggc gatacagttg
     5761 tgattctagg ttctggtcca gtcggtctat tcgctcaaaa attcgctgtt atggctggag
     5821 cagagcgcgt aatcgcagta gatccagtac agcaccgtct agataaagcg gctaattaca
     5881 atggggttga aacttatttc ttagaagaca cggcacaagc tggaacagaa ttgtatgaac
     5941 tggctaaagg tggcgcagat gtcattatcg attgtgtagg aatggacgga ttagagcctg
     6001 tcaaagaaaa agcgaaaaat ttagtaagct tacaaaacgg cacaatctct ccattacaga
     6061 tggcatcgca agctgtcaaa aaatttggaa cagtccaagt aactggtgtt tatatgactc
     6121 cagcttcttc ttacccgctg caagaatttt ttatgcggga tatcgctgtc aagcatggac
     6181 aggcaccaat tatccatcta atgccaaaaa tttacgaaat gattgcagaa ggactattcg
     6241 atcctacaca aatcattact cattcgctgc cactatcaga agcagcacaa gcatatgaga
     6301 tctttgacaa aaaagaagat aaaaatataa aagttgtttt gaaaccttga attcagtaaa
     6361 aaatacaggt gattttcttt atgcccaaaa tcaaacgaaa tacccatgag atcgaaatag
     6421 gaaaagaaga agatatcgaa atacgaggac gtcgcttccg cttctatttc caaaatcgtt
     6481 acacattgat ctcactggct gtcgatttat taaccgggat tttctatatt tttggaagcc
     6541 ttgcttcctt aactaaaatc cccgatcgat atggcaccta tttttatttg gctggtgcta
     6601 ttttcttgac gattcgtcct attctcagaa tcgtaaggaa catttttatt tacgacgaaa
     6661 aaaaagcaat gaagagaaca agcaaaaaaa aagaggcatg agatttgaaa aaatctcatg
     6721 cctctttttt caccctatcg tatcactttg atacagacga gcggtcgtcc cactttcttc
     6781 cttgaccatt gtcaaaaatg tccactcgta tcgttcataa aacgtggtat gatctgtaat
     6841 taagtaaagt ttttcgtacc caagttgatg catttctttt ctgatttccg ctaatatccg
     6901 cttggctatc ccctgcttac gcttttccgg ttcaacaaac agggcacaaa gatttggtgt
     6961 caaatcaggg cggttatgga agtcgttttc aataacgccc gctcctccga cgatggtttc
     7021 tttttcatct aagaccacat accattgagg aatactttcc ttattagcga ttccagtacg
     7081 aatactttcc tcatacacaa cagcaggaac tccccatttt gatgaaaacc acttcgcact
     7141 ttgttttact aattctgggt gttctcttaa tttgatccag ttatatgtaa ccaatgttta
     7201 aacctccgac taaaataaaa cgtttacaaa aattatacaa gtctttatga aaattagcaa
     7261 tgacaacaat agtgatgtaa aaaaaacgga aaacaatcac ttgttctccg ttttttgatt
     7321 aatcaagcat ctaaagcttc ttttcttctt tcttggatcg tagctacctt gacgaacggt
     7381 agatagatca aaatagaaag aaccaaattg acagcggcta gtacaccacc tgcaatactt
     7441 tttgttgcca atacaccgcc aataattggt ggagttaccc atggaggcat aacggtagct
     7501 gctggcacta aacctgtaga agtcgcaaag taagcaacac taactaagac cattggtgtc
     7561 aaaataaatg gaatgaacat gatcgggttc aacacgatag gtaacccaaa catcgttggt
     7621 tcattaatat tgaagacacc tggcgcaatc gacaagtttg ttacaaccat atatggtttg
     7681 tttttacgtc ctactaaata aatagctaac agtaaaccta aagttgcacc tgttcctcct
     7741 aagttgacaa agctgtcaaa gaaaggtttg ttcacgataa acggtgcgct atgtccagct
     7801 gcgattgcat taacgtttgc ttcaatggct ggcgcattga ttgtttgcat caaaggatcg
     7861 accatattcg ctccgtgtaa accaaagaac cataagaatg gtgtgataaa tgcaagcagt
     7921 aaggcagatg gataagagtt tgcaagtccc ataaatggtt cttggaccac tgtatagaaa
     7981 gaacctacga tatcatcaac accgaatgca gcaaaaattg cagcaactaa agcaaacgca
     8041 gagatagtga tcattgctgg tagtaatgaa gcaaatgctt ttgcaactgc cggtggcaca
     8101 ccatcaggca ttttgatgat caatttttca tttccgctta aacgtacaaa gatttctgtt
     8161 gaaataatcc caacaataat agcaataaac aaaccgtttg agctcatacc taatgctccg
     8221 cctaaagcga agaaagagcc taaagaaatc acacctgcgg aaacaccgtc ttttcggtag
     8281 ccgttagcta aatgataagc aagaaagcaa tcaagacaga aagaatggca aatgtaccgt
     8341 tccaagcagc agccccgaat cctttccatg attcaccacc aaaaattgag ttcatcaatt
     8401 cttggaaccc gggaatcggt aagttattga tcattactgc taatgctcct aagatcatta
     8461 acggcatact caccataaat gagtcccgaa tcgcaactaa atgccgttgt gcaccaattt
     8521 ttgatgctac aggtataaaa tgtttctcca taaatgcaac aaatttatcc ataaatcttc
     8581 cctcttttct ttactgtaga ttacgcgttc aatcgacgat acagatcaat gatctctttt
     8641 gctaaatctg taaaagctat ggatgtcatc agatgatctt gactgtggac tgtcaaaagc
     8701 gtgacttcaa cgtgatttcc ttgtgcttct tgtgtcagca tctctgtttg agagtgatgt
     8761 gcttggacta aagattcctc tgcatctttg attttttcat ctgctaaagt gaaatcacct
     8821 tttttcgcag cagcaatcgc ttccattgca tcgctttttg catttccgcc aaacatgatc
     8881 agacccatga tggcttctag atttttttga tcttccattt attgtatcct ccgataattt
     8941 ttattatttg tttattagtt tttctgcttg gtcgagtact ttttcaccat tcatcatgcc
     9001 atagtcagcc atattgatta tatctaaagg aatgccttta ggtgctagct tttcagcaaa
     9061 ttgattttgc ataaagcgta cttgcggtcc taaaagtaaa acgtctacat ttttagattc
     9121 tagttgatta tccgcatctg aagcagatac agcaaagatg tctgcttcca ttccttttgc
     9181 ttctgctgcc ttttgcattt ttgtgactag gagacttgta ctcattccag ctgaacatac
     9241 aagcatgatt gttttctttt ccattttaaa cacgttcctt tctatactta cacttgtata
     9301 taagcaagta gcgtgccaac tttgaaagcg ctttaaaaag ttgatatcat cacatttaag
     9361 gtctatacca agttgcatac acactaaaaa agaaagtgca cactaaacac acaaattaat
     9421 ttttattacc ttttttcttt taacgtgcac aaaaaaagtt gtgacacaaa acttgtcaca
     9481 actttttt
//
LOCUS       DACDLM010000097         8864 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.099, whole genome shotgun sequence.
ACCESSION   DACDLM010000097 DACDLM010000000
VERSION     DACDLM010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8864
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.099"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            3..1457
                     /locus_tag="IV356_002578"
     CDS             3..1457
                     /locus_tag="IV356_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010825391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-acylating methylmalonate-semialdehyde
                     dehydrogenase"
                     /protein_id="HAP9016202.1"
                     /translation="MTRFLRNYIDGRWVASRSTEFEEVMNPATEEALANVPLSSKAET
                     AEAVKAADAAFQTWKKVPVPVRGRYLFKLHQLLTDHKSELARLITLENGKSLSESLGE
                     VQRGIENVEHAAGITNLMMGDSLSTAATDIEITNYRYPIGVIGGITPFNFPMMVPFWI
                     FPMALAAGNTVVLKPSEKTPLLMEKIVELVEKAGFPSGVFNVVYGAHDVVNTLLQDPL
                     VKGISFVGSKNVGEYVYREGTKNLKRVQALTGAKNHVVVLKDANIDRAVKDLIGGAFG
                     SAGERCMAASVIVLEEEIADQFVEKFKAAAKAIKIGNGLDEGVFLGPVIRKDAQQRTF
                     DYIQKGVDEGAKLVLDGRENIPEKGYFVGPTIFDNVTMDMKIWQDEIFAPVASIVRVK
                     DLMAAVELTNESEFANGSCLYTNNASAIRYFRENVDAGMLGVNLGVPAPMAWFAFSGW
                     KHSFFGDLHANGKDSVEFYTHRKVVTARYAQSEI"
     gene            1533..2693
                     /locus_tag="IV356_002579"
     CDS             1533..2693
                     /locus_tag="IV356_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HAP9016203.1"
                     /translation="MNIQLKMPANLRIGGGTIQFLMEESEQLGNKPLIISDTVMEQTG
                     HLQKIKELLGKTDDQLAEYTDIQAEPTQENVYDALKLFQKHQCDHIIAFGGGSCLDTA
                     KVVAVLAANQLSLEAIHARNFDQLQAGIPLIAVSTTAGTGSEVTDVAVITNTKTAVKM
                     MMKDLVFMPQISIVDSDFTKTVPPKVTAATGVDALCHALESYVSVKANEVTQLFSLEA
                     MKKILNTLSQAYENSDDTEAREQMSLASTEAGIAFSNASVTLIHGMSRPVGALFHIPH
                     GISNAMLLPVFFEFSKDAIQTELATIARFIYPAAEDLSLEEAADYLIKKIQELCEQLS
                     IPTIRDYGIDQQAFMAALDKMAADALTSGSPQNNKKVPSHSQIKELYVQAYG"
     gene            2806..3813
                     /locus_tag="IV356_002580"
     CDS             2806..3813
                     /locus_tag="IV356_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP9016204.1"
                     /translation="MRVKVGVIGTGAIGIEHIDRINQKTQGAYVTAVSDINVKAAKEV
                     AKRVDAKFFETGEALIASEDVDVVVVTSWDPTHEQYVLEAIKHGKYVFCEKPLAMDAA
                     GCRRIVDAEVAYGKKLVQVGFMRRYDRGYIELKEAIESKQYGEALMMHCAHRNPSADE
                     NYTTPMAISNTAIHEIDVLRWLLNEDYESVQMILPKKTSNSHADLHDPQLLIFQTKSG
                     VTIDLEIFVNCRFGYDIKCDVVFETAEVGMTDPAYTRIKSEEKNYTPVSPDWQTRFLD
                     AYDYEFKLWIDSIKNDAVVGPTAWDGYVAAITMMACHESRETKTKVMIQMDERPALYN
                     E"
     gene            3837..4862
                     /gene="iolG"
                     /locus_tag="IV356_002581"
     CDS             3837..4862
                     /gene="iolG"
                     /locus_tag="IV356_002581"
                     /EC_number="1.1.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol 2-dehydrogenase"
                     /protein_id="HAP9016205.1"
                     /translation="MNNIRVGIVGLGRLGKVHAQNLATGVSCCELTAACSLVETELAF
                     AQKKLGVKHTFSSYEEMVKSSVIDAVFIVSPSGFHCDQVRLAMENGKHVFTEKPLGLE
                     VEDIKKTQKVIEEHPEQVFMLGFMRRYDESYQYAKKMVEDGEIGEITLIRCYGIDPSE
                     GLESFVKFAMNNDSGGLFLDMAIHDIDLVRWFTGQEVDQVWAIGKNAAYPELDQAGEL
                     ETGAAMMSLSDKTIALLVAGRNAAHGYHVETEIMGTKGMLRVAQAPEKNLVTIMNDQG
                     IIRPCSQNFPERFREAFIREAQEFVSCIQEKRQPAVNAEDGLQSTKIALACQESFDTK
                     SLVQLKK"
     gene            4879..5769
                     /gene="iolE"
                     /locus_tag="IV356_002582"
     CDS             4879..5769
                     /gene="iolE"
                     /locus_tag="IV356_002582"
                     /EC_number="4.2.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015076872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="myo-inosose-2 dehydratase"
                     /protein_id="HAP9016206.1"
                     /translation="MTKQIQLAIAPIAWTNDDMPELGSENTFEQCISEMALAGFTGTE
                     IGNKYPKDPEVLEQYLNIRGLKVASAWFSAFLTTKPFEETAEAFKAHRDFLHAMGAKV
                     IVVAEQGHSIQGIMTAPVFDDKPVFTDEEWKKLAEGLEKLGDLAHEKDMEIVYHHHMG
                     TGVQTTEEIDRLMEMTDPDKVKLLFDTGHLVFSGENPIAVYNRHQDRIKHIHFKDIRQ
                     ETAEEVEKEKDSFLNGVKKGVFTVPGDGMIDFTPIWTAIHASDYEGWIVVEAEQDPAK
                     ANPFEYAVKARSYIREVTGL"
     gene            5792..7387
                     /locus_tag="IV356_002583"
     CDS             5792..7387
                     /locus_tag="IV356_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="solute:sodium symporter family transporter"
                     /protein_id="HAP9016207.1"
                     /translation="MNLFSIISFLVIVICVWLFAYSRSRSVDTSGSEGFFMGGRSLTA
                     LPIAGTIIMTNLSTEQIVGQNGQSYHAGMEVMAWEVTATIAIVALAVIFLPKYFKYGI
                     NTISDFIEIRYDTVTKRIISILFIVTYMTSFLPVVLYSGSLVFNKIFHIDELLGVQPI
                     VAIIIVAMAIGIVGILYLLIGGLSLSANSDSIYGVGLLACGLLVPILGLMKLGDGSFV
                     GGIEHVVVNTPWLLNSVGSIDSAVVPWPTLFTGMLFNNLYFWCTNQMIVQKALSGKNL
                     AEAQKGAFLVGVFKILGALFLVFPGIVARNIFGDSLMSNPDNAYPFLVSEVLPKMIFG
                     IFAAVIFGAILSSFAGALNATSTLFSLDFYKPLINKKANDKQIARAGKTVTVVVGIIS
                     IIVAPFISFAPAGLYQFVQEFNGLYNMPLLVIILFAFYSKKATAFGAKTTIAVHIVLY
                     ALSKMLFQNIHFLYVLTALFVLDIIILMVVSKLKPDGEFVLNSFDTKVDIEPWKYTKV
                     TAIALVVIVILTYVAFSPIGFAG"
     gene            7403..7717
                     /locus_tag="IV356_002584"
     CDS             7403..7717
                     /locus_tag="IV356_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAP9016208.1"
                     /translation="MHKDLLIICETGISASLLVSKMLETIRAKNLSYEIDYATIRNVE
                     EKLNYKDYDVLLLTPQVARSEEKVKEIIKKEKCTAQIVYIKQEDFRYMNIENIIASIE
                     ED"
     gene            8178..>8864
                     /locus_tag="IV356_002585"
     CDS             8178..>8864
                     /locus_tag="IV356_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAP9016209.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIVHGSVES
                     VFNEENLKKAY"
BASE COUNT         2702 a         1615 c         2087 g         2460 t
ORIGIN      
        1 aaatgacaag atttttaaga aattatattg atggtcgttg ggtcgctagt cgctcaacag
       61 agtttgaaga agtaatgaat ccggctacag aagaagcgct ggcgaatgta ccgttgtcta
      121 gcaaagcaga gacagccgaa gcagttaaag ctgccgatgc tgcgtttcaa acttggaaaa
      181 aagttcctgt tcctgttcgc ggacgttatc tgttcaagct gcatcagctt ttaacagatc
      241 ataaaagtga attggcgcgt ttgatcacgc tggaaaatgg gaaatcattg tccgagtcac
      301 tgggagaagt tcaacgagga atcgaaaatg tggagcacgc agcgggaatc accaatttaa
      361 tgatgggaga ttctttatca acagcggcga ctgatattga gatcacgaat tatcgttacc
      421 caatcggagt aatcggaggg atcacaccgt ttaattttcc aatgatggtg cccttctgga
      481 tcttcccgat ggctctggcg gcaggaaata cggtggtgct gaagccttca gaaaaaacac
      541 cattgttgat ggagaaaatt gttgagctgg ttgaaaaagc aggctttcct agcggtgttt
      601 ttaatgttgt ctatggtgcc cacgatgttg tcaacacatt gctgcaagat ccactggtaa
      661 aaggcatcag ctttgtagga tcaaaaaatg tcggtgaata cgtttaccgt gaaggaacaa
      721 aaaatctaaa acgggtacaa gcgttgactg gagcgaaaaa tcatgttgtt gtgctgaaag
      781 atgccaatat tgatcgggca gtcaaggacc ttattggcgg agcttttggt tctgctggtg
      841 aacgctgcat ggcagcctcc gtcattgttt tggaagagga aatcgcggat cagtttgttg
      901 aaaaatttaa ggctgcggca aaagcgatca agatcggcaa tggcttggac gaaggggtct
      961 ttttaggacc agtgattcga aaagatgcac agcagcggac ctttgactat atccaaaaag
     1021 gggtcgatga aggagcgaaa ctggtactag atggtcgcga aaacattcca gaaaaaggct
     1081 attttgttgg accaacgatt tttgataatg tcacgatgga tatgaagatc tggcaggatg
     1141 agatttttgc cccggtcgca tcaatcgtgc gggtaaaaga tttgatggca gccgttgagc
     1201 tgacgaatga atctgaattt gcgaatggtt cgtgtctgta taccaacaac gcatcagcga
     1261 ttcgctactt cagagaaaat gttgatgctg ggatgctggg ggtcaatctt ggggtgcctg
     1321 caccgatggc ttggtttgcc ttttcaggct ggaagcactc tttctttggt gatttgcatg
     1381 ccaatggcaa agacagtgtt gagttttata cccatcggaa agttgttaca gcacgttatg
     1441 cgcaaagtga gatttaaaga tttgcttcga agctctgtta aagagcttcg aggattctgt
     1501 tataggctat aagccagaga gaggtttttt ctgtgaatat tcaactgaaa atgcctgcca
     1561 atttaagaat tggcggcgga acaatccaat ttcttatgga agaatcagaa caactaggca
     1621 acaagccgtt aatcattagt gatacggtta tggaacagac cgggcatctt caaaagatca
     1681 aggagctgtt gggaaaaaca gatgatcaat tagcggagta tacagacatt caagccgaac
     1741 cgacgcaaga aaatgtttat gatgcgctga agctttttca gaagcatcaa tgtgatcata
     1801 tcattgcttt tggtggcggc agctgtctgg atacagccaa ggtggtagcc gttttggctg
     1861 ctaatcaatt aagtctcgaa gcgattcatg caagaaattt tgatcagctg caagcgggca
     1921 ttccgctgat tgcagtgtca acaactgctg gaactggttc ggaagtaacc gatgtggcag
     1981 ttattaccaa tacaaaaaca gcagtcaaaa tgatgatgaa ggatctcgtt ttcatgccac
     2041 agatctcaat cgttgactct gattttacga aaactgtacc accaaaagta accgcggcaa
     2101 cgggagtcga tgcgctatgt cacgctttgg aatcttatgt ttcagtcaaa gccaatgaag
     2161 taacgcaact attttcactg gaagcgatga agaaaatttt gaacacgctt tctcaggcat
     2221 atgaaaatag cgacgacact gaagccagag aacaaatgag cttagcttca acggaggcgg
     2281 ggattgcctt ttcgaatgcg tcagtcacat tgattcatgg aatgagtcga ccggtggggg
     2341 cactttttca cattcctcat gggatatcaa atgcgatgtt attgccggtc ttttttgaat
     2401 tctcaaagga tgctattcag actgagttag cgacgatcgc cagatttatt tatccggcag
     2461 ccgaagattt atcgctggaa gaggctgcgg attatctgat taaaaaaatc caagagctct
     2521 gtgagcagct gtcgatccca acgattcgag attatggtat tgatcagcaa gcgtttatgg
     2581 cagccttaga caaaatggcc gcggatgcgt tgaccagcgg aagtccgcaa aataataaaa
     2641 aggtgcctag tcatagtcaa attaaggaat tatacgtaca agcttatggg tagtaaaagg
     2701 cggagcaaag agagggctct accttttaag aataaaagct acacaggaat aattttgtaa
     2761 gcgcatacta tgtgtgctta aacaacagaa cagggggata agtaattgag agtaaaagta
     2821 ggcgttatcg gaacaggtgc aatcggcatc gagcatatcg acaggatcaa tcagaaaaca
     2881 caaggggctt atgtgacagc agtctcagat atcaatgtaa aagctgctaa agaggttgcc
     2941 aaacgtgtcg atgctaaatt ctttgaaacc ggagaagcat tgatcgcttc tgaagatgtg
     3001 gatgtcgttg ttgtgacttc ttgggacccg acccatgagc agtatgtgtt agaagcaatc
     3061 aagcatggga aatatgtttt ctgcgaaaag ccattagcga tggatgcagc aggctgccgc
     3121 cggatcgttg atgcggaagt tgcttatggg aagaaattgg ttcaggttgg cttcatgcgc
     3181 cgctatgacc gcggctacat tgaactgaaa gaagcaatcg aatcgaagca atacggagaa
     3241 gcattaatga tgcattgtgc ccatagaaat cctagcgcag atgaaaacta cacaacaccg
     3301 atggcgatca gcaacaccgc gattcatgag attgatgtgc ttcgctggtt gctaaatgaa
     3361 gattatgaat ctgttcaaat gatcttgccg aaaaaaacca gcaactccca tgccgatttg
     3421 catgatccgc agctgctgat ctttcaaaca aaatccggtg taacgattga tttggaaatc
     3481 tttgtgaatt gccgctttgg ctacgatatt aaatgtgatg tggttttcga aacggcagaa
     3541 gtaggaatga cggacccagc ctatacacga attaaatcgg aagaaaaaaa ttacacacct
     3601 gtttcaccag attggcagac ccgctttttg gatgcctatg attatgaatt caagctgtgg
     3661 atcgattcga tcaaaaatga tgcggttgtc ggtcctaccg cttgggatgg gtatgtagca
     3721 gcgatcacca tgatggcttg tcatgagtct cgtgaaacaa aaacaaaagt aatgattcaa
     3781 atggatgaac gaccagcact atacaatgag taattctcag aaaacggagg tatttcatga
     3841 acaacattag agtaggcatc gtcggtttag gaagattagg aaaagtacat gcacaaaatt
     3901 tagcaacagg tgtcagttgt tgtgagctta cggctgcgtg cagtttagtt gaaacagaat
     3961 tagcattcgc acagaagaaa ttaggcgtca agcatacttt ttccagctat gaagaaatgg
     4021 tcaaaagttc cgtgatcgat gcagtcttta ttgtttcacc atcaggcttt cactgtgacc
     4081 aagtccgctt ggcgatggaa aatggcaagc atgtctttac tgaaaaacca ttaggccttg
     4141 aagttgaaga tattaaaaag acccaaaaag tcatcgaaga gcatcctgaa caggtcttca
     4201 tgttaggctt catgcgccgc tatgatgagt cgtatcagta tgcgaagaaa atggtagaag
     4261 atggcgaaat cggcgaaatc acactgattc gttgttatgg gatcgatccg agcgaaggct
     4321 tggaaagctt tgtcaaattt gccatgaata acgacagcgg cggcttgttc ttagatatgg
     4381 cgatccatga tattgatttg gttcgctggt ttaccggcca agaagtcgat caagtgtggg
     4441 cgattgggaa aaatgcggcg tatccagaat tggatcaggc tggtgagctt gaaactggag
     4501 ccgcaatgat gagcctgagc gataaaacaa tagctttact agttgccggc agaaacgcag
     4561 cccatggcta tcatgtcgaa acagagatca tgggaaccaa aggaatgctg cgggtagcgc
     4621 aagcgcctga gaaaaatctt gtgacgatca tgaacgatca agggatcatc cgtccatgtt
     4681 cacaaaactt cccagaacga ttcagagaag ccttcattcg tgaagcccaa gaatttgtct
     4741 catgtattca agaaaaacgt caaccagcgg ttaatgcaga agatggattg caatcaacta
     4801 agatcgcgtt ggcttgtcaa gaatcattcg atacgaagag tttagtacaa ctaaaaaaat
     4861 aagcaggagt gtgagaatat gaccaaacaa attcaattag ccatcgcacc aatcgcgtgg
     4921 accaatgatg atatgcccga gcttggtagt gaaaatacct ttgaacaatg tatcagtgaa
     4981 atggcccttg ctgggttcac cggaacagag attggcaaca aatatccaaa agatccagag
     5041 gtgttggaac aatatttgaa tattcgcggc ttaaaggttg ccagtgcatg gttcagtgcg
     5101 tttctgacaa ctaaaccttt tgaagaaact gccgaagcct tcaaagcaca tcgggatttc
     5161 ttacatgcga tgggcgctaa agtcatcgta gtagctgagc agggtcatag tatccaaggg
     5221 attatgacag cgccagtctt tgatgataaa ccagttttca ctgatgaaga gtggaaaaaa
     5281 ctggcggaag gattagaaaa attaggggat ttggcccacg aaaaggatat ggagatcgtt
     5341 taccatcatc acatgggtac cggcgttcaa acgacggaag aaatcgatcg tttaatggaa
     5401 atgactgatc cagacaaagt taaattattg ttcgatacgg gacatttggt cttttctggt
     5461 gaaaatccaa tcgcggttta caaccgtcat caagatcgta tcaaacacat ccatttcaaa
     5521 gatattcgtc aagaaacggc tgaagaagta gaaaaggaaa aagacagctt cttaaacggc
     5581 gtgaagaaag gcgtcttcac ggttcctggt gatgggatga ttgatttcac tccaatctgg
     5641 acagcaatcc atgccagcga ctatgaaggc tggatcgtag ttgaagcaga acaggacccg
     5701 gctaaagcca atccatttga atatgcagtc aaagccagaa gctacattcg agaggtcacc
     5761 ggtctttaat ctattgaaaa ggagctagac gatgaatctt ttttctataa tcagtttcct
     5821 agtgattgtc atctgtgtat ggttatttgc ctattctaga tccagaagtg tcgatacttc
     5881 tggatcagaa gggttcttca tgggagggcg gagcttaact gctttgccaa tcgccggcac
     5941 gatcatcatg acgaacctgt ccaccgaaca aatagtcgga caaaatggtc aaagttatca
     6001 tgcagggatg gaagtaatgg cctgggaagt aactgctacg attgcgatcg tagctttggc
     6061 tgtgatattc ttgccaaaat attttaaata cggcatcaat acaatctcag atttcatcga
     6121 gattcgttat gatacggtta ccaaacgaat tatttcgatc ttatttattg tgacctatat
     6181 gacttctttc ttacccgtgg ttctttattc tggatcgctg gtgttcaata agatcttcca
     6241 tattgatgag ctgctgggcg tccagccgat cgtcgcgatc ataattgtag cgatggcaat
     6301 tggtattgtc ggcatcctct atctgctgat cggcggcttg tcgttaagtg ccaatagtga
     6361 ctccatttat ggagtcggtc tgctggcttg tggtctgctg gtcccaattt taggcttaat
     6421 gaagcttggt gacggcagct ttgttggcgg gatcgaacac gttgtggtaa acacgccatg
     6481 gctgcttaac tctgtgggat cgatcgactc ggctgttgtt ccatggccga cactatttac
     6541 agggatgctg tttaacaatc tgtatttctg gtgtaccaat caaatgatcg tccaaaaagc
     6601 attgtccggc aagaatttag ctgaggcaca aaagggcgct ttcctagtcg gcgtcttcaa
     6661 aatcttaggt gcgttattcc ttgtctttcc agggatcgtc gctcgcaata tttttggcga
     6721 tagtttaatg tcaaatccag ataacgcgta tcctttttta gtcagtgaag tattgcctaa
     6781 aatgatcttt ggtattttcg ccgctgttat ctttggcgcg atcttatcat catttgcggg
     6841 agctttgaac gcgacatcga ccttgttttc actggatttt tataaaccgc ttatcaataa
     6901 gaaagcaaat gataagcaaa tcgctcgtgc tggtaaaaca gtaacggtcg ttgtggggat
     6961 tatctccatt atcgtagcgc cattcatttc ttttgcaccg gctggattgt atcagttcgt
     7021 tcaagaattc aatggactat acaacatgcc gctgctcgtg atcattctct ttgcctttta
     7081 ttcaaaaaaa gcaactgctt ttggggcaaa aacgacgatt gccgtgcata tcgtcttgta
     7141 tgcactatca aaaatgcttt tccaaaatat ccatttcctt tatgttttga cggcattatt
     7201 cgttctggac attatcattt tgatggtggt ttccaaattg aaacctgatg gagaatttgt
     7261 gttgaactca ttcgatacaa aggtcgatat cgagccttgg aaatacacca aggtgactgc
     7321 tatagcattg gtagtcattg ttattttaac ttatgtggca ttttcaccaa ttggctttgc
     7381 aggctaaaaa caggagggta ttatgcataa ggatctattg attatttgcg agaccggaat
     7441 cagtgcgtcg ctgctcgtat caaaaatgct tgaaacgatc agagccaaaa atctatcgta
     7501 tgagatagat tatgcaacga tccgaaacgt tgaagaaaaa ctgaattata aagactatga
     7561 cgttttactt ttaacgccgc aggtcgcacg ttctgaggaa aaagtaaaag aaatcatcaa
     7621 aaaggaaaaa tgtaccgctc agatcgttta tatcaaacaa gaagattttc gttatatgaa
     7681 tattgaaaac atcattgcaa gcatcgaaga agattaacga gaatctttga ttattgagtg
     7741 tcgaggaggt ggtatatgaa aagatggcat gttcgccccg atcaccccaa tatgaagggc
     7801 ggacttatta gaaataccca atcttgtatt tattcaatag ggtaagcgga cctcaatagc
     7861 cagctcatcc ccaaaaagtc gaatggagac acttaaatga gtgtacctat tcgacttttt
     7921 gagactctaa gtcaaatcgt gttgttctca ttaaatcact gaaaggaaat gcttcggcgt
     7981 ttcctttttt ctttttgttt ttcttcgtgt tttgaaaatt acttactatt tactatacga
     8041 gtagtttcaa ataattttga catcctaatc ttcaacaaca gaaaaaaatc taaattataa
     8101 aatttagggt tgactaaaat ataatttttg tataccatat gatcgtgata atcattatca
     8161 tttagaagga gaaagttatg ttagaagtga aaaagcttaa tgtttgttat aacgattttt
     8221 tagcattgaa cgagatttct ttaaaaatac aagaaggtgc tttaacaggt attattggtc
     8281 caaatggtgc tggaaaatct acattgctta aagcaatgtt aaatattatc cctcatcagg
     8341 gagaggtctc cattaataat gaagatatca ataaaaaact ggtgaagatt gcatatgtag
     8401 agcaaaaagc tgatattgat tttacttttc caataaaagt aaaagaatgt gtatctatgg
     8461 gaacatatgc cggaatgaaa gtttttcaaa gaattaaaaa tgcagaatgg caaagagttt
     8521 caaaggcttt ggaaaaggtc gatatgggaa aatattctaa tcatcaaata ggagaattat
     8581 ctggaggaca atttcaacgt gtacttttag caagatgtct tgctcaaaat gcggatttca
     8641 tatttttaga tgaaccattt gtagggatag acttagttag tgaacgaata attatggata
     8701 cgttaaaaga attgaaacat cagggaaaaa cagtgctaat tgtgcatcat gatttaagca
     8761 aggtaaagaa gtattttgat aatattattc ttttgaatcg aaatctaatt gttcacggaa
     8821 gtgtagaatc tgtatttaat gaagagaatt taaaaaaagc ctat
//
LOCUS       DACDLM010000098         8347 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.100, whole genome shotgun sequence.
ACCESSION   DACDLM010000098 DACDLM010000000
VERSION     DACDLM010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8347
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.100"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..376
                     /locus_tag="IV356_002586"
     CDS             <1..376
                     /locus_tag="IV356_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAP9016210.1"
                     /translation="INPDFIETVNYVTNFQREMRKVEAMTVLATQSPQEMVPENMSSD
                     NFSKLKKVFEFSSTKIFMRMDESILRHIEGLVGKSMTNSELESIPQQNQGDAVINFGS
                     KETIRVHFSPNKRQLKLFDGGK"
     gene            376..1581
                     /locus_tag="IV356_002587"
     CDS             376..1581
                     /locus_tag="IV356_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAP9016211.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWLFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMS
                     IITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDP
                     LPFLNSSKK"
     gene            1597..2241
                     /locus_tag="IV356_002588"
     CDS             1597..2241
                     /locus_tag="IV356_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016212.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQAANTYKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPTDDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVIDFSYFTR"
     gene            2252..3058
                     /locus_tag="IV356_002589"
     CDS             2252..3058
                     /locus_tag="IV356_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016213.1"
                     /translation="MSKKKGERQRFKKRKSYLRWLGIFMILGFLILASPIYTNQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIRAKVIKVSDDYFAVKLTHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQLKDQEEIIQKLQEKIDRMTKEKI"
     gene            3080..3310
                     /locus_tag="IV356_002590"
     CDS             3080..3310
                     /locus_tag="IV356_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016214.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
     gene            3856..4131
                     /locus_tag="IV356_002591"
     CDS             3856..4131
                     /locus_tag="IV356_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016215.1"
                     /translation="MDLLIRNIEEKYINKIDKRCEELTVKTGKKWSRNQYLKVLIEND
                     FDHALLNYKKDQFDRLLEKFVDIQTYNTKTLEEYIATNNQLIGLLIE"
     gene            4173..4595
                     /locus_tag="IV356_002592"
     CDS             4173..4595
                     /locus_tag="IV356_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016216.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAEERVE
                     GKIKSNQTKKYSSKLKKPVNESVHTRVDPFDPTKILKR"
     gene            4614..6206
                     /locus_tag="IV356_002593"
     CDS             4614..6206
                     /locus_tag="IV356_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016217.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEMERRTPEE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVISHDNSYLEKMGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEIENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPEKRSEWNYGDENRTKLSPFTRGKLDELTKYVLTKEPGYQEYIQ
                     ISKALKEEAKSLYGESKRETKNAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVN
                     QMQSIYNERSFRTLKQLPTNEYKYSYQEFVKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            6218..6553
                     /locus_tag="IV356_002594"
     CDS             6218..6553
                     /locus_tag="IV356_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016218.1"
                     /translation="MKQYLDQWKVIEGSLKEERIEQLPDCLEKEHLFQISEMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEINEEGINNFPCESI
                     EESISLTEC"
     gene            6700..6894
                     /locus_tag="IV356_002595"
     CDS             6700..6894
                     /locus_tag="IV356_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016219.1"
                     /translation="MTQTTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQNGNI
                     LTLNLTTKMFVDAVENYPFV"
     gene            6926..>8347
                     /locus_tag="IV356_002596"
     CDS             6926..>8347
                     /locus_tag="IV356_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016220.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNNQFQKLFDHQKLTNGQ
                     PMNDKRNGRSWFNQQEKIENKIQSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKEKDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNHPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSSEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKK"
BASE COUNT         3251 a         1268 c         1712 g         2116 t
ORIGIN      
        1 gattaatcca gattttattg aaacggtaaa ttatgtcaca aactttcaac gagaaatgcg
       61 taaagtagaa gcaatgactg ttttagctac acaatcccca caagaaatgg tgccagaaaa
      121 tatgtcttct gataacttct cgaaactgaa gaaagtcttt gaattttctt ctacgaagat
      181 ctttatgcgt atggatgaat ctattttacg tcatatagaa ggattagtgg gtaaatcaat
      241 gacgaactca gaattagaat ccattcctca acaaaatcaa ggagacgctg tgatcaattt
      301 tggctcaaaa gaaaccattc gtgttcattt tagtccgaac aaacgtcaat taaaattgtt
      361 tgatggagga aaataatgga aaaccaaaat gaaagtttaa tcaagcagta tgttaagcgt
      421 cgtgcaaagc ggcgcttatt tttgtggttg tttggtactt ctgcaggttt gattactatt
      481 ttgatcactg tgttcgtgac cctatttcta atacttgcgg cgggctcgat tgataattcg
      541 gattcagatt caagcagtgg tggcgaagct tttacaggag aatattcgga aggcttaccg
      601 atttataaag aaatcaaagg aagaggccct ttttctgatg agattgcgca atatgccgta
      661 ggtgcagcag tgaaatataa attattacca agtgtgatcc tttcgcaata cggttacgaa
      721 tcagcgtttg gtacatcggc gtccgcaaga aatgatctca actattttgg gattacttgg
      781 tttgatggtt gtctgtttcc taaaggaact gcacgaggaa ttggtggcat tgaaggtggc
      841 tggtacatga agtttcccaa ctcaaaagct gcattttcct attacggctt tatggtagcc
      901 acacaatcca attttaatgc ttgtgtagga aataaaagcc ctggcgcaag cttattgatc
      961 ttaggacgag gcggttatgc cgctgcagga attacggaag atagtccgta ttatacaggt
     1021 tgtatgtcaa ttatcacttc taataaatta accgaatatg atgaattcgc catcaaacat
     1081 tggggtgaag gtggcaataa caacggcacg attactggtg aatggacgaa tccattccct
     1141 ggcagcagtt tagataaaag ttccttcagc ggtggtcaat tatttggaac gaatccaggc
     1201 ggtgaattcc gtccgaacgg cttccatgat ggattagatt ttggttcagt tgatcatcca
     1261 ggaagtgaga ttcatgcggt tcatggcgga aaagtcgtgt acgttggcaa tcctggtatt
     1321 tcaggtttgg gcgcgtgtgt gatcgtgatt aattacgatg gcttgaatat ggtgtatcaa
     1381 gaatttgcaa atagtacagg aaattctcga gtgaaagtag gcgatcaagt gaaagttggt
     1441 caagtaattg ggatacgaga tacagcacac ttgcatttag gatttactcg aatggattgg
     1501 cgtcaagcac aaggacatgc attcattgat gatggtacat ggatcgatcc gttaccattt
     1561 ttgaatagca gtaaaaaata gatcaggaga aaaaatatgg aaaataaaac gttaaaaatc
     1621 gtcttaacag ctgcaattag cgttagttta atcggcaata ttgcgttgtt ttggcagctg
     1681 aaagaggaac aagcagcaaa tacctataaa attgaagaag tggctaaaaa cgcgtctgag
     1741 aagctcaaaa aaaattcctc tgaggcacag gcgaagatcg acaagttaaa tcaaaccatc
     1801 aatgagaaaa accaagaaat cgatcagctg aagcaacaag atggcacaaa agcaaaagag
     1861 gaagtaactg aagcacaaag aaagacggca gaagagttcg gtcaattggc cattgataaa
     1921 tcattaagca gaaatgaatt aacggaaaaa ctaaaagatg tcgcaaccca agaagtgatc
     1981 gacaaattaa gtcctacaga cgatgatcac caacatgatg attacggaag ttactccttt
     2041 acattaggtg acgtgcaaac ttacgctcaa acaagcagtg taaaagagga acaaaatttt
     2101 gtcgtatttg ttgattatac aatcggcaat ccgcaattca aagatgtcaa accacaaaaa
     2161 ataaaaggtg gattaactgt cactgaaaaa caagtagatg gtcaatggaa agtcatagac
     2221 tttagttatt tcactcgtta ggaggaagaa aatgagtaag aaaaaaggag aaagacaacg
     2281 tttcaaaaaa cgaaaaagtt atcttagatg gctgggaatc tttatgattc tcggcttttt
     2341 gattcttgct agtccgattt atacgaatca gaaggtagat ataccagatg aggtaagcac
     2401 gaacgccttt ttaaacacga aagagctgac aatggtttca aaagaaaaag gagcgaacca
     2461 gcaattagtt tttgaatttg cgatcgatga tgaagatcaa agcttgttaa aagaactggc
     2521 taatcttaat tatcgcgtag aagtaaagac agctaaaggg gattatcaag caatacgagc
     2581 caaagtgatt aaggtgtctg atgattattt tgcagtgaag ctaacgcatg taccagaaga
     2641 atatatcgcc atgcgtttaa ccattattcc tgaaaaaatt gatccaaaag tggatatgca
     2701 agaaccacaa gatctgattt attacgtgca cgaagataag gttaaagatc aagtgaaaga
     2761 tgaagattat gaacaacacg cgatcaatta caaagtgaaa ggatacaaga aagaacaaaa
     2821 agcagctcaa aaacaaatgg aatctttcca agcaaccatt gatttgaatg aagaattagt
     2881 gaagaagcta aaagatcaat tgccttatca agtcgcagat gatcaggaaa atactgaaaa
     2941 caagattaat agctaccagc aagaaattga aacatcgaaa acgcaactga aagatcaaga
     3001 agagatcatt caaaaacttc aagaaaaaat tgatcgtatg acaaaagaaa agatttagaa
     3061 ggacaggtgg agtgaaaaaa tgaagcgaac aaacttggct gacaaagata ctttcgctga
     3121 gcagaaagta ttgattaaag cctatctcaa agttgtaaaa gctaaagaaa tatgtcgaga
     3181 agtgaattta tctaacacaa caatatctga gttgaagaat ggtcgaaaga atttagatac
     3241 tttaaaattc agatcatttg aagctctata tgtagctgct aaaaaatatt ttacagctga
     3301 taacaaataa aaaacaggag tattttatgt gaaaaaagta tataaaaaat gcttatgaat
     3361 cagctatatc accttaacca tttgttaatg agatgggaga aaacattaac cacgattcta
     3421 acgcaaacat caagcacata aaacatttaa cactcctcct ttctggctga agatttcaac
     3481 caaacaggaa gacagcgtat caattatagc atacactttt tcttaaattc atttttcata
     3541 tgacaaaata tttccttcta atcgacaaag ttagaaggat tttttattgt ctaaatacac
     3601 aaataacctt aatttttaaa gagcataagg aaacgtgata tcactttctc acgaaaggtg
     3661 ttaggtaggc tgtgcctacc acgtttctaa gaaagataaa tgatatcaaa attttggatt
     3721 tgtgtgtaga tttgtgggta ggatgaaagc gaatgtgggc agtaaaataa gcgtttgtgt
     3781 gtagcaaaat caaaaaatgt gtagggatat gtgtagctac acatatccct acacataata
     3841 aatttggagg aaaatatgga cttattaatt agaaatattg aagaaaagta tattaataaa
     3901 attgacaaac gttgtgaaga acttacggtc aagactggca aaaaatggag tcgaaatcaa
     3961 tacctaaaag ttttgatcga aaatgatttt gatcacgctc ttctgaatta taaaaaagac
     4021 caatttgatc ggttgttaga aaaatttgtg gatattcaaa cttataatac gaaaacttta
     4081 gaagaatata ttgcaacaaa taatcaatta attggtttgt taattgaata ataaaaatag
     4141 tattgtgaat ttataaaagg aggaaatcaa ttttggcaaa agcaacaaga aaacatgtat
     4201 atctttacga tatgcatatc gaagtacttg atgaaataat ttctactcat gaagatatat
     4261 ctaattatag tgaagcagtc agacatttgt gtatgatgta tgatccaaaa atcgaagaaa
     4321 aaataaatcc aattcaaatt aaattgaatg caatgggaaa agaaatttct attttaaccg
     4381 aaatggtttc agagtttgcg gatcttcatt tgaaagatac aggaatacta attggtacaa
     4441 attcaactgt ttatcaagaa gcagaagaac gtgtggaagg aaaaattaaa tccaatcaaa
     4501 ccaaaaaata ttcttctaag ttaaagaaac cagtgaatga atctgttcat accagagtag
     4561 atccatttga tccaacgaag attctaaaaa gataaaagta gaaggagaac gtgatgaata
     4621 aatcgcctgc agttattctt acttgtcaat ttaccttgcc caataaaaaa tctttttcaa
     4681 catacattga ttatatgaca agagaaaaag cactggaaga aatggaacga cgtacgcccg
     4741 aagaagaaca ggaactgcaa cgaatcaaga atgctttaga ggatttttat attcctgaag
     4801 gagaaacttt ttcggaaagt aagacggata aagaattcag tgaaacgtcg aatgaagctc
     4861 aatcgttgat ggaacatgga atcaattttg acaagttaga ggaacaagat tttaccaaat
     4921 atctttctta tatgacccgt cactatgcgt tagaacaaaa gaaagaactg acgcaaaggg
     4981 aacaaaaaga ataccaacgg ttgaaccaag caatgaaaaa atatcaaaca gagccacata
     5041 aaaaagcttc aggaaatctt cctggagttt tttctatggc ttcagacgaa gtgaaaggaa
     5101 gtgatctgaa ggagatcaaa caaatcttcc aaagaggaca acaaaaaggc tcaatcattt
     5161 atcaagatgt tatctctcac gacaattcgt atcttgaaaa aatgggcttg tacgatccca
     5221 aaacagatac cttagatgaa gaaggtttga aagcagctgg aagaaaaatg atggagacat
     5281 tattcgagaa agaacaattg aatgaaacag gttactggat ggcaacgatt caccgtaaca
     5341 ctaagcatat ccatattcat tttgcagttg ttgaaaaaga aaatacgcgt aaaccgtata
     5401 ctgagattga aaatggtgtg agttatatcg taccgaaggg gaagagaaga caagcaacat
     5461 tagacgcaat gaaaaccaat tatgtacatg agttagaacg tttctcttat gaaaaggatc
     5521 gaatgatcgg tatggagaaa cgaaatttat tgacacgaaa aagtgatttg cgtaacacct
     5581 taacaaaagt agtaaaagaa ccagcacgtt acgatcgaca cgccatgaac ttattaaatg
     5641 aagtatataa aaccctacct gaaaaacgtt cggaatggaa ttatggagat gaaaatcgaa
     5701 ccaagctttc accatttaca aggggaaaac ttgatgagtt aaccaaatat gttttaacaa
     5761 aagaacctgg atatcaagaa tatatacaga tttcaaaagc attgaaagaa gaagccaaaa
     5821 gcctttatgg ggaaagcaaa agagaaacaa agaatgcaga aaaaaacgcc ctctttgatt
     5881 taaaaaagcg cacaggaaat gcgattttaa cagaactgaa gagacaggat agtcaaataa
     5941 aaccattaat agaaagtgtc aatcagatgc aatctattta caatgaacga tcctttcgaa
     6001 cactcaaaca gttgccaaca aatgaataca agtatagtta tcaagaattc gtaaagcgta
     6061 ggaaacaatt ccaacaaaga gttgtcacgc agcgaagctt gcgtcaatta aatcgaacaa
     6121 ttaatgcaca tgaagaaaaa taccacgcaa gtaaagcata tgaagagcaa cagcgaagaa
     6181 tccaaatgga acaagaaaga caataggagg aagagaaatg aaacaatatt tagatcaatg
     6241 gaaagtcata gaaggatcac taaaagaaga acgaatcgaa caacttcctg attgtttaga
     6301 aaaagagcat ttgtttcaga taagcgaaat gttgagaaac gaacagtttg atccaaatca
     6361 atttttagtt gttgagtacc cagctactgg tgtgtattgt tgtaatcatg tgaagggtga
     6421 aaaatatttt attattcaag aatacgaagg taagttagcg ccttattata ctacttggga
     6481 aataaatgaa gagggaatca ataatttccc atgtgaaagc attgaagagt ctatttctct
     6541 cacggaatgt taaataaata gagacgtaaa agagtcctga acgtgattgt ccaggactct
     6601 ttttcaatga attgttttcc gccaattcac tgagtggtgc gattcaattt tattatatca
     6661 aaagaaagtg agattccaaa gtgaagggag gaagaagaaa tgactcagac aacgattggt
     6721 gttgtggttg aaaaaagcag ggataatctc gtttttgtga cagaaattca aacaggtaga
     6781 gcttttgtag tcacagacaa agctgcaaaa gcgtatcaaa atggcaatat tttaacgtta
     6841 aatctgacta cgaagatgtt cgttgatgca gtagaaaatt atccatttgt ttagacaaac
     6901 gatattttac aaggaggaaa cggacatggc agaagaaaaa gaaccactag ataatagtcg
     6961 gttgggaaag tccaaaagaa aattagtacg gttgcaaaac gaattaaata atcaatttca
     7021 aaagctattt gatcaccaaa aattgacaaa tgggcaacca atgaatgaca aacgaaatgg
     7081 tcgttcatgg tttaaccagc aagaaaaaat agaaaataaa atacaaagtt tgagagaaga
     7141 gatcaagcaa caagaaaaac aggtagaaaa acttgaaaga caagaagagc taaaggaaat
     7201 gggctataac aagtacggcg gactggatat gacgatcgat aatattccaa gaatcaaaga
     7261 agaaatcgaa cgctttgaaa aaggtgaatc gactttttca gccgccacga tccgaaaata
     7321 tcaacggaag ttggaaacat tagaacagct gaaagaaaaa tcagaaaaag gaaaagaaaa
     7381 tatcctccct gaagtacaag cgatcattga cagcggacga gtgacgcaat ggaaaaaaaa
     7441 tccaaccatt tattttttga aaggctatcg aaaagttgct ttagaactga atgaaaacgg
     7501 gggatttgag gaatcaaaaa aataccaagc cacgtcggaa gaggaaaaag cagctgttcg
     7561 tgaattactt gaagaggctg caccaactga ttctctgaag gagaaagaaa aagatcattt
     7621 ctatcgagta gaattcaacg aaaatgatcc agaaaaagga ttgaaaagtt atggtgggga
     7681 gatcgtaaca ttagaattga tcgatcaact taaaacgttg gataaccaat acgctgcaga
     7741 agcaggttat tataaattct attttgaaga agtgaagaac ggagaagtag tagatcagat
     7801 ccgaatggat ctaggggatg gcgtcaacag taatcacccc atctatttag agttagcaaa
     7861 attgtgcgaa caagtacctg agaaggaaca aaaacaatcg gtcaaaaatg aacctgtttc
     7921 gaaagaacaa atgcagtcga aagaaacaaa aacaaaacaa aagggctatc aaaaacgaac
     7981 ggcagaagag atcaaacaag aagttaaatc cctttcgcaa caggcactgg atgcggtgaa
     8041 aaagcatacc cattcttctg aagacgtcaa agaacttttg aactttatgt ctcgttttcc
     8101 agaacgatcc tttagaaatc aattattgat tgaggaacaa tttccaggtg caacggcttg
     8161 tttaggtcgt gccgcgttga aaaaagaagg aatctatatc aaaaaagggg aacaagggaa
     8221 caagatcttt gtcagaaaaa cggtcaaagg attttatgag aaaggacgtg gctttgttcg
     8281 agaaacagaa gctacaccag aagataaaaa acgaatcgaa agtggtcaaa tcgaagtgat
     8341 caaaaaa
//
LOCUS       DACDLM010000099         8344 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.101, whole genome shotgun sequence.
ACCESSION   DACDLM010000099 DACDLM010000000
VERSION     DACDLM010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8344
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.101"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            430..597
                     /locus_tag="IV356_002597"
     CDS             430..597
                     /locus_tag="IV356_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP9016221.1"
                     /translation="MVYLNKKQTCEFLGIDNNTLDKWIRIYNFPVIKIDGIIRFDVED
                     IKGFMDTFKKI"
     gene            671..1897
                     /locus_tag="IV356_002598"
     CDS             671..1897
                     /locus_tag="IV356_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP9016222.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFKEITGISSEKFQKTFPTRQLAIKA
                     ENEMKKKIAKVLREENANSLELKGQIKFKEFYKSKWLPRYELGQTTRSHKAPSDITII
                     NTKNLFRLHILPIFGEYAMSYLNANTEIISDELTKKSKEYANIKIIKCYVRSMFDIAE
                     VLNYIEFNRTTKIIQSITAPKKVALEEKRIREGKQALSSKELTDWLDAVRDDFNDQLL
                     SFHDYTLFMLTLYLGDRKSETYALQWKYIDFENQTVRLKYALDKHTKKKFTKGRKDTI
                     IQVPEIVMTLLQEWKSVQAEQLLKLKIKQTPDQYLFSYSKPSGEVNCPVHTDYLNYRI
                     NSIKKRHPHLVHLTPHKLRHTYATLARQGGADMNQISNALTHSGISTTKIYVNTPDLV
                     DKAVFEAFQRGLQKSN"
     gene            complement(2055..2672)
                     /locus_tag="IV356_002599"
     CDS             complement(2055..2672)
                     /locus_tag="IV356_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP9016223.1"
                     /translation="MAKIGYARVSSLDQNLDRQLELLSECDKIFSDKASGKDTNREGF
                     QEMMKFIREGDIVVVTELKRLGRNNKELTETMNLIQLKKATLEVLNLPALTGITDDNL
                     RRLLNNLIIELYKYQAEEERRYIRETQQQGIALAKAKGKYKGGTLKYRENDPRLQLAF
                     NLFLTGSTDKEVEELTGINRRTFRRYRMKHGITNEVREQKNKSFS"
     gene            complement(3355..4350)
                     /locus_tag="IV356_002600"
     CDS             complement(3355..4350)
                     /locus_tag="IV356_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP9016224.1"
                     /translation="MRPKLEDVAKRANVSKTTVSRVLNNRGYLSQKTIDNVYKAIEEL
                     NYQPNVVARQLFQKKTNIVGLLFPTVANPFFSELVEALEKKLYEIGYKVLIGNSMNNK
                     EKETNYLNQLLSDQVDGLIVGTHNQGIQEYKYQNLPIVAIDRVMNEDIPVVESDNYNG
                     GKLATKLLIAQGAKNIIHTNGPIDLQTPANRRRLAYEDTMKAYQLIPRTVTLDFNISY
                     VKKKQIFFQMFEDYPKIDGIFASNDIDAALILQVAKEKGLNVPADLLVVGYDGTLMTR
                     SILPDLTTVIQPINDIADTAVAILMKRINKEETKKEYILPVTLWMGKTSVKKKNN"
     gene            complement(4445..5317)
                     /locus_tag="IV356_002601"
     CDS             complement(4445..5317)
                     /locus_tag="IV356_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP9016225.1"
                     /translation="MLIGSIEAGGTKFVCAVGDEDYRVQDQIICPTTTPRETLKKTVD
                     YFKQFDINALGIASFGPIEIRKNSPKSGYITSTPKVGWRNVNVLGYLQDELNVPMSWT
                     TDVNGSAYGEYIMSTLSNEKINSLVYYTVGTGVGGGAVVDGKLLGSFGHSEMGHTFVK
                     RHPDDIDFKGICPYHGDCLEGLVAGPTFEARFGKKGEDVSLTDPIWDVMAYYLAQAVI
                     QTTLIIRPDKIVFGGSVVNEKLLEKIRVNVNKLLDDYVEIPPLSKYITRPLIKNNGSA
                     TLGNFALGLNQLQE"
     gene            complement(5330..6757)
                     /locus_tag="IV356_002602"
     CDS             complement(5330..6757)
                     /locus_tag="IV356_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HAP9016226.1"
                     /translation="MTKRAIELTNTRYRLGYHVSAPSGWINDPNGFCYFDGYYHVFYQ
                     HHPYSAEWGPMHWAHARSKDLVHWESLPLALTPGDQEDEGGCFSGSAIEKNGVLYLFY
                     TGHHYYGDNDPDHFWQNQNMAYSTDGIHFTKYEKNPVIAKAPEDNTHHFRDPKVWKHD
                     EKYYMVLGSQEKDGLGRAIVYQSLDLLNWDYIGPISKAKEVLTEGFMWECPDFFELNG
                     KSILLLSPQGIEANGKDYLNLYETGYFIGDYDYETAKFIRGNFYELDKGHDFYATQTT
                     LSPDGRRIVMAWMDMWESPMPEKVDGWAGALTLPRELELIGDRLYMKPVRELEQLRVG
                     SGVETTVNLAGEIIIAQDASFKEALIDVLLTKSKNQEVKFSLKTKDEELINIFYSKDK
                     NECTLTRNGKNDPRYGTIQMCDRLSLRVFIDKSSAEIFINDGELVFTERYYTENQPSM
                     HLSVSEEAFVSSTIYHLKKDAISYE"
     gene            complement(6811..8085)
                     /locus_tag="IV356_002603"
     CDS             complement(6811..8085)
                     /locus_tag="IV356_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP9016227.1"
                     /translation="MSKVNVFKNQSYLQSSATLLLFFASWGVWWSFFQLWLTSESNGL
                     GLSGSAVGTVFSANSLVTLILMFIYGTLQDKLYIKRNLLIFASVLATLVGPFFIWIYG
                     PLLDNNFNLGIIMGALFLSAGYLASVGVFEAVSERFSRLFGFEYGQARAWGSFGYALV
                     ALLAGFLFVKNPHLNFWAGSFFGSLLLLNLLFWNPKVEREANQNFNQEQAESNSIPSL
                     KEMFDLMKLPQLWTIIIFIVFTWTFYTVFDQQMFPGFYTGLFSTSANGEKIYGTLNAI
                     QVFCEALMMGIVPIIMRKLGVRNTLLLGVTIMCVRIGLCGFASTPLSVSCIKMLHALE
                     VPLFTLPMFRYFTLHFDTKLSATLYMIGFQIAAQIGQVILSTPLGILRDNVGYQPTFK
                     IISLIVLLAGIYAFFILKQDDRDVQGDPFIRG"
BASE COUNT         2767 a         1534 c         1193 g         2850 t
ORIGIN      
        1 ttaaattttt acatacctgt ttatgaaaaa ctaaataatc tgtcaaaaaa atatgattgt
       61 tcatttctaa atatgttttc caattttaaa atctttttta gcatttttgt ttccttttca
      121 tatggttttt cgttgttaat agtgactagg atgatattcc tattttgacc attgacaatt
      181 aaatataatt tttgaataac gttccctgct attcgagcta agaattcaag tacgccatga
      241 cctatttagc gataactact tagagatttc tttttgtttt gggaagacaa aatgccatga
      301 caatagcagt agataatgat acttccgtaa ggctcgccgt aaactgggga gaggtgaaat
      361 tcctatgtgc ttacccaagt caattcaaaa attttagttc atttataagg ggatgatttt
      421 attaaatcaa tagtctatct aaacaaaaaa caaacctgtg agtttttagg aattgataac
      481 aatactttag ataaatggat tcgtatatat aattttcccg taataaaaat agacggtata
      541 attcgctttg atgtagaaga tatcaaaggc tttatggata cgttcaaaaa gatttgaatt
      601 ttacttttga ctgcatatac taaaagtagc gaaatatact gccttacttt tttattaagg
      661 agtgaggaag ttgcctacga agctttcaaa tggaaaatat aaaactaatt tgagatatcc
      721 aaaaaaattt aaagaaatta caggtatcag ttcagaaaaa ttccaaaaaa catttccaac
      781 taggcaattg gctattaaag ccgaaaatga aatgaaaaag aaaatcgcaa aagtcttaag
      841 agaggagaat gcaaattcat tagagctcaa aggtcaaata aaattcaagg agttttataa
      901 atctaaatgg cttcctagat atgagttagg gcaaactact agatcccata aagctccaag
      961 cgatataacc atcattaata caaagaattt atttcgattg catattctgc ctatatttgg
     1021 tgagtatgcc atgagctatc ttaatgcaaa taccgaaata atatcagatg aactcacaaa
     1081 aaagtcgaag gaatatgcaa acataaaaat cattaaatgc tatgttcgtt ccatgtttga
     1141 tattgcagag gttctaaatt atattgaatt taatcgtaca acaaaaataa ttcaaagtat
     1201 tactgcacct aagaaagttg ctctggaaga aaaaagaata cgagaaggaa aacaagcttt
     1261 atcttcgaaa gaactcactg attggttaga cgctgtaaga gatgatttca atgatcaatt
     1321 actttccttt cacgattaca ctctttttat gcttacttta tatcttgggg atagaaagag
     1381 tgagacctat gctttgcaat ggaaatacat tgattttgaa aaccaaacag tccgtcttaa
     1441 atatgccttg gataaacaca caaaaaagaa atttacaaaa ggtcgaaaag atactattat
     1501 ccaagttccg gaaattgtaa tgacactatt gcaagaatgg aaatcagtgc aagctgaaca
     1561 actattgaag ttgaaaatta aacagacacc tgaccaatat ctttttagtt actccaaacc
     1621 ttctggtgaa gtaaattgtc cagtccatac tgattactta aattatcgaa ttaattctat
     1681 aaaaaaaaga catccccatt tggttcattt aactcctcat aaacttcgac atacttacgc
     1741 aactttagct agacaaggtg gggctgatat gaatcaaatt tctaacgctt tgacacattc
     1801 aggtatttca actacaaaaa tttatgtgaa tacacctgat ttagttgata aagctgtgtt
     1861 cgaagcgttt cagcgaggat tacaaaaatc taattaatgt gttctagaat gtgttctaaa
     1921 tataaaaaaa agacactttc caaataattg gaaagcgtct tgaacgttga tatataaagg
     1981 atattaacgt tttgagaatt gagatgcttt acgagctttc ttaagacctg gtttcttgca
     2041 aaattatatt agcctcaact gaaagattta tttttttgct ccctaacttc attagtaata
     2101 ccatgtttca ttcgatatct tctaaacgtt ctacgattaa tccctgttag ctcttcaact
     2161 tctttatctg tagatccagt caaaaacaaa ttaaatgcta attgaagtcg cggatcattc
     2221 tcacgatatt ttagcgtacc tcccttgtat ttcccttttg ctttagcgag tgcaattcct
     2281 tgttgttgcg tttcgcgaat ataccgacgt tcttcttcgg cctggtactt gtatagttcg
     2341 ataattaagt tattaagtaa tcgacgtaaa ttatcatcag tgatacctgt taacgctggc
     2401 aaattcaaaa cttccagtgt agctttcttc agctgaatta aattcatcgt ttctgttagc
     2461 tctttattat ttcgtccaag tcgttttaat tctgtcacaa cgacaatatc accttcacgt
     2521 atgaatttca tcatttcttg aaatccttct cgattggtat ctttcccact tgctttatca
     2581 ctaaaaattt tatcacactc tgataataat tctaattgtc ggtctaaatt ttgatctaag
     2641 ctgcttactc gagcataccc aattttcgcc ataataaaac tcctttaaaa ttctgaaatc
     2701 cggatcattt ttaaattctg ttgcccaact ctgttgtcat ttttctagat aaatggcata
     2761 aattttcagc gctaagtgac aaaagcaact aatttttcat gatagatttt taaatatctc
     2821 aatctatctc caaaattagt tgcttttgta gctatagttg actatgaata tgacaaataa
     2881 ttagaaaaaa ctgtgccaat taaatataaa aatgacactc atttacattc aatagaacac
     2941 caagagccca acagggtata ctctggtgtc cttttaaaaa agtaactttc tgacctaatt
     3001 aattgagcta ctaaaaaagc tatgaaatga ggaataaaaa agggatcaaa aacttttaag
     3061 tttctgaccc ttttgagttc taattatttc ttccagaacg aagaatgtta tctgctttat
     3121 ctgcaattga ttctgttaga aggactgaaa aatttatgcc agcccttttg cctagcttat
     3181 ccgcccattg aggaattgtt aaggtttttc tgacaagttc tatgtctttc aaatatttgg
     3241 caacatctac acagattaaa agcatgattt tgtatcatag tctattataa gagatttaac
     3301 aattttttat atcacgaatt aataatgaaa ttatcattga tagtctttat aaatttaatt
     3361 gttctttttc tttactgatg tcttccccat ccataatgtg acaggtaaaa tatattcctt
     3421 ttttgtttct tctttattta ttcgtttcat caaaatagca acagctgtgt ctgctatatc
     3481 attaattggt tgtattactg ttgtcagatc tggtaatata ctccgagtca ttaaagtacc
     3541 atcatatccg actactaata aatcagctgg tacatttaac cccttttctt ttgctacttg
     3601 taatattagg gccgcatcga tgtcatttga agcaaaaata ccatctattt taggataatc
     3661 ctcaaacatt tggaaaaaaa tctgtttttt ctttacataa gaaatattga aatctaatgt
     3721 cacagttcgt ggaattaact gatatgcttt catagtatct tcataggcta gtctccgacg
     3781 attagccgga gtctgtaagt caattggacc gtttgtatga ataatatttt ttgcaccttg
     3841 tgcaattaat aacttggttg caagttttcc accattgtag ttatcggatt caacaactgg
     3901 aatatcttca ttcatcactc gatcaattgc aacaatcggt aaattctgat atttatattc
     3961 ctgaattcct tggttatgtg taccaacaat taaaccatct acttgatcag acaataactg
     4021 atttaaataa tttgtttcct tttctttatt attcatcgaa ttgcctatta ataccttata
     4081 accaatttca tataactttt tttccaatgc ctcaacgagt tcactaaaaa aaggattggc
     4141 tactgtagga aatagtaacc cgacaatgtt agttttcttt tgaaataatt gacgcgctac
     4201 aacgttcggt tgataattga gttcttctat agccttataa acattatcaa tcgttttttg
     4261 acttaaatag ccacgattgt ttaatacacg tgaaacagtt gtttttgata catttgctct
     4321 tttggcaaca tcttctaatt ttgggcgcat tctcttgtct ctcctaaata atgcaataat
     4381 taactatcga aaaaaagaac tctatagaac tactatacct gataatcgat attttttcta
     4441 tgttttattc ttgtaattga ttcaagccca aagcaaagtt tcctagtgtt gccgatccat
     4501 tatttttaat taaaggacgc gtaatatatt tacttaacgg tggtatttcc acgtaatcat
     4561 ccaataattt attaacatta acacgaattt tttctaacaa tttttcattt actacgcttc
     4621 caccaaatac tattttatcc ggtcgtataa tcaatgttgt ttgaatcaca gcttgtgcta
     4681 gataataggc cattacatcc caaataggat ccgttaaaga aacgtcttca cccttttttc
     4741 caaaacgtgc ttcaaacgtt ggtcccgcaa ctaagccttc taaacaatca ccatgataag
     4801 gacaaattcc tttaaaatca atatcatcag gatggcgttt tacaaacgta tggcccattt
     4861 ctgaatgacc aaacgatcct aatagttttc cgtcaacaac agctccacca ccaacgccag
     4921 taccaacggt gtaataaact aatgaattta ttttttcatt cgataaagtg gacatgatgt
     4981 actctccata agctgatccg ttcacatccg ttgtccaaga cattggaaca ttcagctcat
     5041 cttgtaaata acctaacaca ttaacatttc gccatcccac ctttggtgta gacgtaatat
     5101 atcctgattt tggtgaattt tttcgaattt ctattggacc aaatgatgca atacctaatg
     5161 catttatatc aaactgttta aaatagtcaa cagttttttt caatgtttcc ctgggggtgg
     5221 tcgttggaca aattatttgg tcttgtactc ggtaatcctc gtctcccacg gcacatacaa
     5281 atttagtccc acctgcttct atgctaccaa ttaacatcat aaaacctcct tactcgtaag
     5341 aaattgcatc tttttttaga tgataaattg tactcgagac aaaagcttct tcactaacac
     5401 tcaaatgcat acttggttga ttttctgtat aataacgctc tgtaaaaaca agctcgccat
     5461 cattaataaa aatctctgcc gaacttttat cgataaacac tcgaagtgat aatctatcac
     5521 acatctgaat ggttccatac cttggatcat ttttgccgtt acgagttaag gtacattcat
     5581 ttttatcctt agaataaaaa atattgatta actcttcatc ttttgttttt aatgaaaatt
     5641 tgacttcttg attttttgat ttagtcaata gtacatcaat tagagcttct ttgaatgaag
     5701 catcttgagc gattattatt tctcctgcca aattaactgt cgtttcaacg ccgctgccaa
     5761 ctcgaagttg ttctaattct ctcacaggtt tcatatacaa acgatctcca attaactcta
     5821 attctcgagg aagcgttaat gctcctgccc atccgtctac tttttcaggc atagggcttt
     5881 cccacatatc catccaggcc ataacaatac gtctaccatc tggagataaa gttgtttgtg
     5941 ttgcatagaa atcgtgtccc ttatctaatt cataaaaatt tcctctaatg aattttgctg
     6001 tctcataatc ataatcaccg ataaagtagc ctgtttcata tagatttaaa taatcttttc
     6061 catttgcttc aattccctga ggggataata aaagaataga ttttccattt aattcaaaaa
     6121 agtctgggca ttcccacata aatccttctg taagtacttc cttcgcttta gaaattggtc
     6181 caatgtaatc ccaatttaat aaatctaacg actgataaac aatagcacga cctaatccat
     6241 ctttttcttg actacccaaa accatgtaat atttttcatc gtgtttccat acttttggat
     6301 ctctgaaatg atgtgtgtta tcttctggtg cttttgctat tacaggattt ttttcatatt
     6361 tagtaaagtg aatgccatcc gtactatacg ccatgttttg attttgccaa aaatgatctg
     6421 gatcattgtc tccataatag tgatgtcctg tatagaacag atacaacaca ccattttttt
     6481 caatagcgct tcctgaaaaa caaccacctt catcttcttg atctccagga gtcaaagcaa
     6541 gtggtaaaga ttcccaatga actaaatcct tacttctagc atgtgcccag tgcattggtc
     6601 cccattcagc actatatgga tgatgttgat aaaacacatg ataataccca tcaaaatagc
     6661 aaaatccatt tggatcatta atccatcctg atggtgcaga cacatgatat cccaaacgat
     6721 aacgtgtatt tgttaattct atagctcttt ttgtcataat atattcgctc actttctaga
     6781 taaaattgtt ttttattctg ttggtttcca ttatcctcga ataaatggat ccccttgaac
     6841 atctctatca tcttgtttaa gaataaagaa tgcatatatg cctgctagta atacaataag
     6901 agaaataatt ttaaatgttg gttgatagcc aacgttgtct cttaatattc ccaatggtgt
     6961 tgataaaatc acttgcccaa tttgagcagc tatctgaaat cctatcatat agagggttgc
     7021 tgatagcttt gtatcaaaat gaagtgtaaa atagcgaaac attggtaatg taaataatgg
     7081 tacttctaaa gcatgcaaca tttttatgca tgaaacagat aatggtgtcg aggcaaaccc
     7141 gcacaatcca attcgtacac acataatggt tacacctaat aacaaagtat ttcgaacccc
     7201 taattttctc ataatgattg gaacaattcc catcattaac gcttcacaaa atacttgaat
     7261 agcattcaat gtcccatata ttttttcacc attagctgat gttgaaaaca aaccagtata
     7321 aaatcccgga aacatttgtt gatcgaatac cgtataaaat gtccatgtaa aaacaataaa
     7381 gatgattatc gtccataatt gaggcagttt cattagatca aacatttctt ttaaagaagg
     7441 aatactattt gattcagctt gttcttgatt aaaattttga tttgcttccc gttcaacttt
     7501 agggttccaa aataataaat ttaacaatag taaagaacca aagaaagatc ccgcccaaaa
     7561 gtttaaatga ggatttttta caaataaaaa tcctgccaaa agcgctacca aggcataacc
     7621 aaatgatccc cacgcccttg cttgtccata ttcaaagcca aataaacgac taaacctttc
     7681 tgacacagct tcaaaaactc ctacagaagc taaatatcca gctgacaaaa atagcgctcc
     7741 cataataatg cctaaattaa aattgttatc tagcaatggc ccatatatcc atataaaaaa
     7801 tggtccaaca agtgtcgcta atacagaagc aaaaattaat aaatttcgtt taatatacaa
     7861 tttatcttgt aatgttccat aaataaacat caaaattaag gtaactaacg aatttgccga
     7921 gaatactgtt cctacagcac tgccagataa ccctaaacca tttgattcag atgttagcca
     7981 aagttgaaaa aatgaccacc aaacacccca agaagcaaaa aatagtaata atgtagctga
     8041 actttgtaaa taagattgat ttttaaatac gttaactttt gacatatttt tatcctccaa
     8101 cgatatattt gtatcccctt tcatgataac cggttaacat ttttagaaaa ggacttgtac
     8161 tcctaaaatt ataaaagaaa tccgcttaca tgtcaaccgg ttattctatt tggataatgc
     8221 catataatgt cacaggatat gacttttatt ggtgtgtcgc ttttcttttt taatggcact
     8281 attttttata acgccgtttg tataattaag cgagacaaat aaaaaagcca tttatgttac
     8341 actc
//
LOCUS       DACDLM010000100         8286 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.102, whole genome shotgun sequence.
ACCESSION   DACDLM010000100 DACDLM010000000
VERSION     DACDLM010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8286
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.102"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            328..1251
                     /gene="truB"
                     /locus_tag="IV356_002604"
     CDS             328..1251
                     /gene="truB"
                     /locus_tag="IV356_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HAP9016228.1"
                     /translation="MDGLLTLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEEKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVKRFKRVDITDEVWQKVKNGMRLNYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            1255..2196
                     /gene="ribF"
                     /locus_tag="IV356_002605"
     CDS             1255..2196
                     /gene="ribF"
                     /locus_tag="IV356_002605"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HAP9016229.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGEIWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            2591..3376
                     /locus_tag="IV356_002606"
     CDS             2591..3376
                     /locus_tag="IV356_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP9016230.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWINNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENDKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            3389..4240
                     /locus_tag="IV356_002607"
     CDS             3389..4240
                     /locus_tag="IV356_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HAP9016231.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(4364..4816)
                     /locus_tag="IV356_002608"
     CDS             complement(4364..4816)
                     /locus_tag="IV356_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP9016232.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQIREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNHVVNFSQWINEKLLMQTDISLVS"
     gene            complement(5281..5649)
                     /locus_tag="IV356_002609"
     CDS             complement(5281..5649)
                     /locus_tag="IV356_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chaperone"
                     /protein_id="HAP9016233.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            5799..6281
                     /locus_tag="IV356_002610"
     CDS             5799..6281
                     /locus_tag="IV356_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HAP9016234.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            6318..7328
                     /locus_tag="IV356_002611"
     CDS             6318..7328
                     /locus_tag="IV356_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HAP9016235.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPPWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQPSEKYQKEWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTISHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(7443..8156)
                     /locus_tag="IV356_002612"
     CDS             complement(7443..8156)
                     /locus_tag="IV356_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016236.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIKQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLINVIVMDN"
BASE COUNT         2811 a         1342 c         1680 g         2453 t
ORIGIN      
        1 ttaagaaact gaaaaaataa ataaaaaaaa acggaaaaaa gactggaaga atggacagtc
       61 ttttttttcg tttttgggaa gtgaaaacca aactatttac ctgtaagcca cccataaatc
      121 caatcaaatg gtgcaaagaa aaaatcttcc attctattcc ctcctttaaa aaaaacataa
      181 catgatttct atttacgtga gcatgaattt tgttacgttt ttattgccga aaaataaaaa
      241 ccgttcatta tgatgtcaaa ttcgtcagta attgatgcaa tgtgttataa taattcagtt
      301 aaatcaaaaa tgaaatggag aaaagacatg gacgggttat taactttatg gaaagaacgc
      361 ggaatgacaa gtcatgattg cgtattcaaa ttaagaaaaa tcttacatac gaaaaaaatc
      421 ggacatgggg gtacgcttga cccagacgta gacggtgtgt tgcccatttg tattggaaaa
      481 gccacaaaag ttatcgaata tttgacagat tctgggaaaa tctatgtagg cgagataact
      541 ctaggtttca gtacaacgac ggaagatcga tccggagaac gggtagaaac aaaaccagta
      601 gatatgtctt tatctgaaga aaaaatagat gaagtgatgg cttcatttat tggtgagatc
      661 acccagatac caccaatgta ctcagcggta aaagtcaacg gtaagcggtt atatgaatat
      721 gcccgcaata atgaaacagt ggagcgtcct gttagaaagg ctcagattta ccgttttatc
      781 cggacaagtg aattgacaag agacgaagtg acaggaacca tttcttggcg cttcgaagta
      841 gaatgcggga aaggaaccta tgtccgcaca ttagctgtag atacaggcaa gaaacttggt
      901 taccctgcgc acatgtctga tctgacccga acagcaagtg ccggtatgtc ccagaaagat
      961 gctctgacat tagaagaagt agctcaagct gtgaaaaatg ggacaatcga tgattgtttg
     1021 ctgccaatag aaaaaggagt gaaacgattc aaacgagtag atattactga tgaagtatgg
     1081 cagaaagtaa aaaacggtat gagacttaat tatactgtat ttgcgctccc agaaatgccg
     1141 tcagaagaaa ttgctttgtt ttataaaggc aaagttgtca gtatctatca gccaaacccg
     1201 aaagaaaaaa acaaattaaa acctagtaaa gtattgagaa atgaggaata acgaatgaat
     1261 atcatcaaga tcagacatcc ttaccaatca gaacaaattc cagaagacga tgtcgtttta
     1321 gtactaggat tttttgacgg cgtgcatatt ggacaccaga aagtcataaa gacaggtatg
     1381 gaaattgcac aaaaagaagg attgaaatta gcattgatga ctttcaatca gcatccatcg
     1441 attgtcttta aaaagatcga tcctagcagc gtgaaatatt tgactagcct taagcaaaaa
     1501 gaagaaaaaa tggccgcttt gggtatagat tatttatatg aagttgattt tacttcttct
     1561 tttgctcatt tagcaccgca ggaatttgtt gatcaataca tcgtagggtt acatgcaaaa
     1621 tatgctgttt ccggttttga ttatacgtat ggaccaaaag acattgcaga tgtcgctcat
     1681 tttcctgaat atgccaaagg aagattcaaa atcgtcacag tttctaaaga agaagaacaa
     1741 ggtgaaaaaa tcagctctac ccgtattcga ggattactag acagcggaca agtaaaagaa
     1801 gcagcaaaac tattaggttg cacatatgag gtagaagggg tagttgtcca tggcgatgca
     1861 cgaggcagac tactaggatt ccctacagca aatgtcaaag taaagagcac agttcatttg
     1921 cctaaagaag gtgtttatgt atcggaaata aaaattgggg aaatttggta tccagccatg
     1981 ggttcaattg gacataatga tacattcggt gaaggacggg agctgactgt agaattgtat
     2041 attttggact ttaatcaaga tatctatggt gaacatgtcg cagtacgctg gaatcaattt
     2101 ttaagagatc aagtgaaatt ttctagtgta gaggaattga ttgaacaact caaagaggat
     2161 gaacaagcaa cagctgaata tttttctcag caataaaaca ttatgcataa aatctcttgt
     2221 ttatgtataa ctagcaattt caataaaatg ggtgataaat aagcccagga aaggggctgt
     2281 gacaaaagtc ttgtcacagc ctttttttcc aaataaatgg tttttcagaa gtagcttctt
     2341 cggaaataag ccgaaatttc acaaaaattt gagaagtaat ttttgtaaat tacttcttat
     2401 ttcttgaagc tggccacttc tgtcacaacc tctttcttta tagaaataaa aggacactag
     2461 caattcatga aaacgattgc taaagcgtat catttgcttt agactatata tcttggtgta
     2521 cactcacttt aagacggaaa taaaagttat ccgtaataac aggtttaggt atgaaaaagg
     2581 agtgggtact atgtataagg aattagaaaa caaagtcgca gtagtaactg gtggctcaaa
     2641 ggggattgga acagcgattg ctcaacgatt cgggaaagaa aaaatgaatg tagttgtcaa
     2701 ctataactcg gataaagaag gagcagaaaa agcagtcaaa gcaatcgaag aggcaggcgg
     2761 aaaagcagtc tctgtacaag cagatgtcag ttctgaagaa ggaatacagc gtttacttga
     2821 tacggcttta gaaaattttg ggacactgga cgtttggatt aataatgctg ggatggaaaa
     2881 tcagcatcca acccatgaac ttagccttga agattgggaa agagtattaa aagtcaattt
     2941 gactggcgtt tttatcggaa cgaaagcggc tttaaattac tttacagaga atgataaaaa
     3001 aggaaatatc atcaatatgt cttctgttca tgaacaaatc ccatggccaa cgtttgctca
     3061 ttacgctgct tcaaaaggcg gagtaaaact attcaccgaa acggtagcaa tggagtacgc
     3121 accaaaggga atcagaatca atagtatagg acctggtgct atccgtacac ctattaatgc
     3181 ggcaaaattt gatgatcctg aacaaaaaga actcttggaa agtatgatcc cactaggacg
     3241 cgtaggtgaa ccaaaagaaa tagcggcgac agctgcatgg ttggcttcag acgaatccag
     3301 ttatgttaca ggtattacac tatttgcaga tggtgggatg actttatatc cttctttcca
     3361 aggtggaaaa ggataagggt gaataaaaat gggtttattg attgcattga tcccggcagt
     3421 tgggtggggg atccagccac tgattttgaa aaagattggt ggcagaccaa caaatgagat
     3481 attaggaact ggtattggag ccgtgctcgt tggcttactt gttcaattat tcgcttctcc
     3541 agctggtatt tcagtgacta catttttgat tagtttactt tctggtgcat tctgggtcat
     3601 cggacaaaca ggacagtata catctttcaa cttgattggt gtttctaaaa cgatgccaat
     3661 ttcgactgca ttacagttag tcggaacctc attgattggt gtcttcgctt ttggagaatg
     3721 gtctggaagt atgggaaaaa tcattggtgc agcagcaatc attcttcttg tatttggttc
     3781 tgctttaacg gcaatcagtg atgatcctgg aaaaaaaggc ggtatcacaa aaggaatcag
     3841 tctattagca tcaacaagta ttggttattg ggtttacagt gcattgccca aactagttga
     3901 tgcaagcgga ctttccattt tctttccgca aatgatcggt gtctttttag gggcagtgat
     3961 ttatgtgatt ttccgaaaac caaccgcatt ttctgaagac aagagttgga aagcaacaat
     4021 agttggagcc atcttcagtg tgtcagcatt ggcttatatt ttttcagcaa atgaaaatgg
     4081 ggttgctact gcatatatca ttacacagct aaacgtagtt atctctacat taggcggtat
     4141 gtacatcctg catgaaaata agacaccaaa agaaaaaaaa ttaacgatta tcggattatt
     4201 gctgatcgta gtaggaagca tggtcacggt ctttatttga ggataaagat ggtaaaatct
     4261 catttattaa aaaaatattt gtttgaacca aacagtaagt acttataaaa aaatagcgct
     4321 agaatttcca acatctctgg aatttctagc gctttttaat tgtttaagat acaagtgaaa
     4381 tatctgtctg catcaataat ttttcattga tccattgact aaaatttacg acatgattga
     4441 agttaccacc gattagtatc tccgcatgat tgtctttata aagatcgtat tgtaaaagac
     4501 ggtctttttt atttgcgtaa acatcgttat ggtactggac taattgttct cggatttgat
     4561 tgattgctgt aaaatcacga tactgaaggt tgaaacgcat cgtgattggt gcatttagca
     4621 tgaatcgctg catttctttt gctgcttcct ctgcttgatc tccgtatagg aactcaaaaa
     4681 gattacgttc agaaaatttc cattgcccgc caacctttgt tccttttagt tttccttcat
     4741 gaagataatt tctgatagaa cgtgtagtaa cacctaattg ttcggctaat tcatttactg
     4801 agtaaaaatc tttcaatgtt caccctccta tgtgaatggt tctactgact tagttgatat
     4861 ttgcttaatc acgaaatgta gaaagaacga ttttaattaa ggtcattgta aaaatcaagt
     4921 cagaaaattc taacttttct ttctctaaag aaattcgttc tctcctaaag tgatattata
     4981 tttaaatata cctgaaaata atgggcagta ttatgaaaga tcactgatat tttctcgtat
     5041 tttttcctta ttcaaaagtt ttgcaggaaa attgctgaaa aaataatttt actaagtgga
     5101 aaattcaaag ccattcaatc agtgattttt ttcagcacaa gaaagactcc ttataaaaat
     5161 agcagatact ttgtcaatta agtgtttaac cagggatgat aaaaaggata ggattgaaca
     5221 aaacctgtat aagctgatga atagtttcct cgccagtaaa aggtttattc gtataaagct
     5281 ttatcgccaa aatttatcat gacctttttt atcttcaata ttaaatgaaa tcaattgttc
     5341 aatcaattcc cagttgatta cacttttcca aggaactttg atgacgttat ccgtatatac
     5401 gtagcctgct tcttggatat ttttttcaag ggcacgaatc gctgcttttt ccggtgcgat
     5461 agaaaaatga tttttagcaa aactaaatgc aataataaag gtaccatggt cagtaaacat
     5521 aggttggttc cattttacag ttgtgtctag ctggggatac gtttctgtta tcttagcaaa
     5581 aaggtctttg atcttttgtt gatgttcttt ttctttgatc tgattgatga tcggctgaaa
     5641 tttttccatt ctaaaacgcc tccattaagt ggtttgattt attttaccag aaaaacaata
     5701 gttatgtata aaaaacgaac aaaacacaag taatgttgta accgctatat ttatatgata
     5761 agatgtctca aataataaaa tagaaaagag acataaaaat gattgacttg gcaaagaaat
     5821 tcttacacga aaatatatat tttgagttgt atcatcatcg agccatttat acaaatgaag
     5881 atgctttggt aataaagaaa gaacaaggat ttacaggtac agagaccaaa agcttattct
     5941 taaaagataa aaaagataat aactacgtat atctgacttt tactacgaaa caaacggatt
     6001 tcaaagcatt agggaagatc gtcggtaaaa ggctttctat tgtttcatca gaacgcatgg
     6061 aagaacaaac gggacaaaag cagggcgctg tttctccgtt tggttatgaa aaacagattc
     6121 cgattattat tgatgaagag ctcttatcaa atgaaaaact tgtttttgca ccaggtagac
     6181 cagatcaaac gatggtcatc caaacggttg acttaaacaa aatcatccag ctacttgaga
     6241 tgccgatatt tttgatgccg gcaaacgaaa aaaacaatta accaagtaaa atagtgcata
     6301 cttggaggtg aagcaacatg ataagttatc cattattaga aagaaatgca acgattgggg
     6361 ttactgcacc atcctcaggc gtatcagagg aacaccattc gttactcgaa tcagctttaa
     6421 agagaatgga agaaaaatct ttccaagtag ttactggaaa gacgctttgg acgcaagata
     6481 aggaaaaatc aggtccagca agaaaacgag cagatgaatt caatcaaatg atgcaagatg
     6541 aaaatatcca aatgatcttt ccgccttggg gaggagaatt attgattgag attctcgatt
     6601 ttgtcgattt tgatgctcta caaccaaaat ggatagtagg ttattcagat attagtacgt
     6661 tgctacttgc tgtcacatta aaaacaggga tagccactgc acatggaacc aaccttattg
     6721 atttaagagg agagtacttg gatgaaacga cagcaatgtg ggaaagtgta ctgaaaacaa
     6781 gagaaggaga atcgattcta cagcaacctt ctgaaaagta tcaaaaagag tggccccatg
     6841 agcattcatc atcttctgtt ttccatctca ctgaaccaac aaattggcaa tcagtcagcg
     6901 gagatgcagt aaggatgaag ggacgattat taggtggctg tattgatacg atcagtcatt
     6961 taatcggtac cccttatgga gatgtccaat cttttaaaag aaagtataat gatggaaagc
     7021 cgatcttgtg gtttctagaa aattgtgagc tatcgtcagt tgatttaaga agatcacttg
     7081 ttcagatgaa actggcagga tggtttgatg gcagctcggg gatcatgttc ggtagaagtg
     7141 cagcagagga tttgttagat tataaaatga aggatgtata tgaagatctg tcaaaggaat
     7201 taaaactacc gatcttgtat gatattgatt gtggtcatgt accgccacaa ctgacattga
     7261 tcaatggtgc ctatgcagaa gtagcggtag aagatagaaa agcgactgtt ttgcaaacgt
     7321 ttatttaaaa aattttttcc tgccttggag tttatcaaag accaacaaat ctaaatagaa
     7381 aagaaaatga aagaagctga cagtattttg ccagcttctt tttgtatgat ctattagaaa
     7441 ttttaattat ccataactat cacattgatc agctgtttca catcatttgg attacctgta
     7501 ggaatagcta ctacagatgc attatcaata atttcttgag ttgtttctct aatgaacgct
     7561 ggataagatg tttgatctgc aggcatttgc caatgtgaag gaactggata actagtgatt
     7621 gtcccgtcat ggttacttga atacactaaa actccctggt aactgtattt cccagtgagc
     7681 ataaccacat ctttcggata gactgcactc cctgcatcat aaggggcgat aggtgttcct
     7741 gcaggataat gaataacatg tagttcgaaa tcacccgatg tatctctaaa agtattacct
     7801 ctaattgcta gccaaacacg tgcgtactca atttgtagat cagaatatcc tgctaacgga
     7861 tctattgact gagaagactg tgaggaagtt gtgtctattg ttgaagaaga aatatttgtc
     7921 tcaactgtac tactagatgt agaagaagta ttgggctctg agactttact gcttgttgaa
     7981 gatgtattcg tttcagtaga agctgatttc tgagtacttg atttttcagc tgaactggtt
     8041 tgtttgattg aacttttgtc tgtggtcgca gatggatcac tattttcttt actaggagac
     8101 gtacatccta caaggaataa agagaccaac aataaaataa aacctaactt tttcatataa
     8161 aatacctcat tattttttta ataccagtat agcataatcc tgaatttttg aatccgtaaa
     8221 accttgtcta tggataggct acaattaact agacagaaaa attaaggtgt gtagactaga
     8281 agaaaa
//
LOCUS       DACDLM010000101         8251 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.103, whole genome shotgun sequence.
ACCESSION   DACDLM010000101 DACDLM010000000
VERSION     DACDLM010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8251
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.103"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..197
                     /locus_tag="IV356_002613"
     CDS             <1..197
                     /locus_tag="IV356_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016237.1"
                     /translation="WFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLIIAIIAVGLV
                     FNAAGVKDILLELFNRIIGA"
     gene            314..811
                     /locus_tag="IV356_002614"
     CDS             314..811
                     /locus_tag="IV356_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAP9016238.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSISELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMSDVARYYIEETGALGEVPASLQNYIDYESYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            898..1290
                     /locus_tag="IV356_002615"
     CDS             898..1290
                     /locus_tag="IV356_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP9016239.1"
                     /translation="MKKIRSYTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAV
                     MILGNLPPLSMIEGAFLKYFGIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRRKLTY
                     AGKKVTLGRNQPQEAITAVRSEFYGISN"
     gene            1274..3721
                     /locus_tag="IV356_002616"
     CDS             1274..3721
                     /locus_tag="IV356_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP9016240.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSILSAQERSKNEVTGKLKTVAYDKIDQQTDALISM
                     IGENQVDYRFFIGFKLLLNDQEFSMKSLTVEAKNAFTDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYPLSKKKLEH
                     ETLIKTYDLIKPTRCLVEEKQRYLKIQQEDETAYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVNLTSDEKNKGLLDPYVIMKNTKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSDGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            3724..5907
                     /locus_tag="IV356_002617"
     CDS             3724..5907
                     /locus_tag="IV356_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAP9016241.1"
                     /translation="MKPSILNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVTPSGLSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHALMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNMTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRM
                     MRKPRMLMHAHMHRLQRKLGRSVTALGAGSAIASATGKKGQSGSGSSASTQADHSRPN
                     GQEKSTLGKRIGQTIGTVADTKDRMVDTAGNLKEQVKDLPTNARYAVYQGKSKVTDNV
                     HDLTRSISQTKADKASGRKKQQEQRRKTIAERRSEMEQVKQKKQPASSVHERPATKQE
                     QSHDGQTSRQTTVQASYRESQQAKQERPTVKSDSSSLKTERQSNTVQERTVQKPVTST
                     APTDRASQRSITKERQSTVQRVPLQNTKSRPPIKTATIKKGSKKP"
     gene            5904..6905
                     /locus_tag="IV356_002618"
     CDS             5904..6905
                     /locus_tag="IV356_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAP9016242.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDGGFSNIHYGGV
                     DVSAEVLAHKPMVEKVAKEYGIEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLGVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGDEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKFEGWKYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTRHIPLLEAKA
                     GDLVFFHSTYNAGSYITHIGIYLGDNRMFHAGDPIGYADLTSSYWQQHLVGAGRIKQ"
     gene            6920..7834
                     /locus_tag="IV356_002619"
     CDS             6920..7834
                     /locus_tag="IV356_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP9016243.1"
                     /translation="MMKFGKNQNTEKQTPKEKKPRVYKVNPRKKVVIVLWVLLGLSFS
                     FAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWELNDKSIDNRIEN
                     LKAYLTEELQALNVDTVRKDIPVSSSVKGFQIWTVEADGDNQFDVTYSVDQLITEGEN
                     TKTVHSAYIVSVYVDSTGNMVLIKNPTITSIPKKSDYKPKAIESEGTVDSITTNEINE
                     FLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIYNRKDNQVTVSLTVEY
                     IDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            8079..8195
                     /locus_tag="IV356_002620"
     CDS             8079..8195
                     /locus_tag="IV356_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HAP9016244.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
BASE COUNT         2569 a         1568 c         1754 g         2360 t
ORIGIN      
        1 actggtttct atcaaacgct caatcactgg tgcttttagc aatcgttgtg attggcttgt
       61 atcttggctt caagcgtgag tttagcaaac tgattggctt tttaattatt gcgattattg
      121 cggttggctt agtcttcaac gctgctggag taaaagacat tttactagag ctattcaatc
      181 gcattattgg tgcttaaata aaaccgttct tttgtggaat ataagtggtt ttcttatgtt
      241 ccgcaaagga atggtacacc aaacgaagtg cggtagggat ttttgaatct ctacaaagaa
      301 aggacgtgaa tatatggacg atatgcaagt ctatattgcg aatttaggca aatacaatga
      361 gggcgaattg gtcggtgcgt ggtttacctt tcccattgac tttgaggaag tcaaagagaa
      421 aatcggcttg aatgatgaat atgaggaata cgccattcat gattacgagt taccctttac
      481 ggttgacgaa tacacttcta ttagcgaact caatcgccta tgggaaatgg tatcggagtt
      541 gccagaagaa ctacaatcgg agctatctgc tctgctcact catttttcaa gtattgaaga
      601 actaagcgaa catcaagaag atattatcat tcattccgat tgtgatgata tgtctgacgt
      661 ggcacgctac tacattgaag aaacgggtgc tttaggcgaa gtgccagcca gtcttcaaaa
      721 ctatattgat tatgaatcct atggtcggga tttagacctt tcgggaacgt ttatctcaac
      781 caatcacggg atttttgaaa tcgtctatta aatctgtcgg tacattctta ctggcagatt
      841 ttcttgttta cggggtagtc aaaagactat ccccattttt atgaaaggat tgattacatg
      901 aagaaaatac gaagctatac cagtatctgg tctgttgaga aagtgttgta ctccatcaat
      961 gactttagac ttccgtttcc cataaccttt acgcaaatga catggtttgt cgtgtcactc
     1021 tttgcagtta tgatacttgg caacttgccc cctctttcta tgatagaggg agcatttctc
     1081 aaatactttg ggattcctgt ggctttcaca tggtttatgt ctacaaaaac ctttgatggt
     1141 aaaaagcctt atggattttt gaagtctgtc attgcttatg cactgcgacg aaagctgacc
     1201 tatgcaggaa aaaaagtaac gcttggcaga aaccagccac aagaagccat tacagcagtt
     1261 aggagtgaat tttatggcat atccaattaa atatattgaa aacaatctgg tctggaataa
     1321 agatggggaa tgttacgctt actatgagct tgttccctac aattactcat ttctaagtcc
     1381 ggaacagaaa atacaagtac atgattcttt cagacagctt atcgcacaaa atcgtgatgg
     1441 caagattcat gctttacaaa tcagtacaga atccagcata ctttctgcac aagaacgttc
     1501 caaaaatgaa gtcactggaa agctcaaaac ggttgcctat gacaaaatcg accaacagac
     1561 agacgcttta atatccatga ttggcgaaaa tcaagtggac taccgtttct ttatcggttt
     1621 taagttgctt ctcaacgatc aggagttttc tatgaaaagt cttaccgttg aagcaaaaaa
     1681 tgcttttact gattttgtct atgatgtgaa ccataagctg atgggcgatt ttgttagtat
     1741 gagtaatgat gaaatcctgc gttttcagaa gatggaaaag cttttagaaa ataaaatctc
     1801 ccgtcgtttc aaaatccgaa gattagataa ggatgacttc ggctatctga ttgaacacct
     1861 ttacggacag acaggcactg cctatgaaga gtatgagtat cctctatcaa agaaaaagct
     1921 ggaacatgaa acactgatta aaacctatga cctcattaag cctactcgct gtctggtgga
     1981 agaaaaacag cgatatttga aaatccagca ggaagacgaa accgcctatg tagcttactt
     2041 taccatcaac agtattgtcg gcgaactgga cttcccgtcc tctgaaatct tctactacca
     2101 gcaacagcaa tttacctttc cgattgatac gtcaatgaat gtggaaattg tagcgaatcg
     2161 taaagcccta tctactgtcc gcaataaaaa gaaagaactg aaagacttgg ataaccacgc
     2221 ttggcaaagt gataatgaaa ccagctctaa tgtggcggaa gctctggaaa gtgtgaacga
     2281 gctggaaacc aatttagacc aaagcaagga atctatgtat aagctgtcct atgttgtaag
     2341 ggtatcagca aatgaccttg acgaacttaa acgtcgttgt aatgaagtga aagatttcta
     2401 tgatgatttg agcgtgaaac tggtacgacc ttttggggat atgctgggct tacatgaaga
     2461 atttttacct gccagcaaaa gatatatgaa tgactatatt caatacgtga cctctgattt
     2521 cctcgctggt ttaggttttg gtgctactca aatgctgggt gaaaatgagg ggatttatgt
     2581 tggctacagc ttagatactg gacgcaatgt ctatctgaaa cctgctcttg ccagtcaagg
     2641 ggttaagggt tcagtaacca atgcgttagc gtctgccttt gtcggttcgc tgggtggtgg
     2701 taaatccttt gcgaataacc ttatcgtcta ttatgcagtg ctttatgggg cacaagcagt
     2761 gattgtagac ccaaaagcag aacgtggcag atggaaagaa accttgccag agatttccca
     2821 tgaaatcaat atcgtcaatc tgacttctga tgagaaaaac aaaggcttac ttgaccctta
     2881 tgtaattatg aaaaatacca aagattctga atcactggct attgatattt tgacattcct
     2941 tacggggatt tcctctcgtg atggggaacg cttcccaatc cttagaaaag ccattcgtgc
     3001 agtaaccaat agtgaagtgc gagggttgat gaaagtgatt gaagaattac gggttgagaa
     3061 tacgccacta agtaccagca tagccgacca tatcgaaagt tttacagact atgactttgc
     3121 ccatctgctt tttagtgatg gttatgtaga gcagtctatc agccttgaaa aacaactgaa
     3181 cattatacag gttgccgact tggtacttcc tgacaaggaa acttcctttg aggaatatac
     3241 cacaatggag ttactatcgg tagcaatgct gattgtcatt agtacctttg cgttggactt
     3301 tatccataca gaccgaagta ttttcaagat tgtagactta gacgaagcat ggagcttctt
     3361 acaggtggca caagggaaaa cactatctat gaagctggtt cgtgctggtc gtgctatgaa
     3421 cgctggggta tatttcgtga cccaaaatac agatgacctc ttagatgaaa aactgaaaaa
     3481 taacctcggc ttaaaatttg cctttcgttc cactgacctt aacgagatta aaaaaaccct
     3541 tgcctttttt ggtgtagacc cagaggacga aaacaatcag aagcgattgc gtgatttgga
     3601 aaacgggcaa tgccttatca gtgatttata tggtcgtgtc ggtgtgatac agttccaccc
     3661 tgtatttgaa gaactgctcc atgcctttga taccagacca cctgtgcgaa aagaggtgta
     3721 aatgtgaaac catcaatatt aaacagaata aaatcaaact ggacgctgaa acgtctaggt
     3781 aaagtggcaa tgacagtggc tttcacactt gtgattgcca tttttctttt agccatgctg
     3841 ggaacggtgg ttcaagctgc gggcttggta gatgatacgg tcaatgtggc aaatgaatac
     3901 agccgatacc cacttgaaaa ctatcaactg gatttttatg tggataatag ctggggctgg
     3961 ctaccgtgga actggtcgga cggaattgga aaacaagtca tgtatggact atatgccatt
     4021 accaatttta tttggacaat cagtctttat gtttccaatg cgacgggtta cttagtacag
     4081 gaagcctatt ccttagactt catttccgct acagcagatt ccattggcaa gaatatgcag
     4141 acccttgcag gggttacgcc tagtggacta tcaacagagg gtttctatgt tggattcctt
     4201 ttactcttga ttttggttct tggggtttat gttgcctata caggactgat aaagagagaa
     4261 accacaaagg caattcatgc cctcatgaat tttgtgctgg tttttatcct atcggcttcc
     4321 tttattgcct acgctcccga ctacattaaa aaaatcaatg acttttcatc agacatcagc
     4381 aacgctagtt tgtcactggg tacaaaaatt gtcatgcccc attcagatag tcaaggcaag
     4441 gacagtgtgg acttgatacg tgacagccta ttttccatac aggttcagca accgtggcta
     4501 ctgcttcaat ataacagttc agacattgaa agtattggta ttgaccgtgt ggaaagcctg
     4561 ctctcaacca gtccagattc caacaatggg gaagacagag aaaaaattgt tgcggaagaa
     4621 attgaagata gaagcaatac caatatgacg attacaaaga cgattaaccg tttaggtaca
     4681 gtcttcttcc tatttgtctt caatattggg atttccatat ttgtattcct attaacagga
     4741 atcatgattt tctcgcaggt actttttatc atctatgcta tgtttctgcc tgtgagcttt
     4801 attttaagca tgattccatc atttgatggt atgtcaaaac gagccataac aaagctcttt
     4861 aataccattt tgacacgagc tggaatcaca ttgattatta cgacagcatt tagtatttca
     4921 accatgctct ataccttatc ggctggttat ccgttctttt tgattgcttt tctacagatt
     4981 gtgacctttg caggaatcta ctttaagctg ggcgatttaa tgagtatgtt ttctctacag
     5041 agtaacgatt ctcaaagtgt gggaagtcgt atgatgagaa aacctcgtat gcttatgcac
     5101 gctcacatgc accgtctaca gcggaaactt ggacgctccg tgactgcttt aggggctggg
     5161 tctgccattg ccagtgctac gggtaaaaaa ggacagtcgg gttcgggaag ttctgcgagt
     5221 acacaagcag atcactctcg accaaacggg caggaaaaat caacactagg aaagcgtatc
     5281 ggtcaaacca tcggtacagt agctgatacc aaagacagaa tggtagatac tgctggtaat
     5341 ttgaaagaac aggttaagga tttgccgacc aatgcaagat atgcagtata tcaaggaaaa
     5401 tctaaagtga cggataatgt ccatgattta accagaagta tttctcaaac caaagcggat
     5461 aaagccagtg gacgcaagaa acagcaggaa caaagacgga aaaccattgc ggagcgtcgc
     5521 tctgaaatgg aacaggtcaa acagaaaaaa cagccagctt cttccgttca tgaaagacca
     5581 gccactaagc aagaacaatc tcatgatgga cagacttcaa ggcaaacaac tgtacaggct
     5641 tcctataggg aatctcaaca agccaaacaa gagcgtccaa cagttaagtc cgattcttca
     5701 agtttaaaaa cggaacgtca aagtaataca gttcaagaaa gaacggttca aaagccagta
     5761 acttcaactg caccaacaga tagagcttca caacgttcaa tcacaaaaga acgtcagtct
     5821 actgttcaaa gagtaccact acaaaataca aaaagtagac caccaatcaa aaccgccacc
     5881 attaagaaag gcagtaagaa accatgaagc tgaaaacttt agtgattggt ggttcgggat
     5941 tattcttgat ggtcttctca ctgcttctgt ttgtcgccat tttattttca gatgaacaag
     6001 atggcggttt ttccaacatt cactatggcg gtgtggatgt ttccgcagaa gtgctggctc
     6061 ataagcctat ggtagaaaaa gttgccaaag aatatggaat tgaagaatac gtcaatatac
     6121 ttcttgcgat tatacaggtg gaatcgggtg gtacagcaga agatgttatg cagtcctcgg
     6181 aatccctcgg tcttccacct aattcattga gtacagaaga atccattaag caaggtgtga
     6241 agtatttcag tgagttatta gccagtagcg aaaggcttgg tgtagattta gaatcggtta
     6301 tccagtccta caattatggt ggtggtttct taggatatgt ggctaatcgt gggaataaat
     6361 atacctttga actggctcaa agtttctcaa aagagtattc gggtgacgaa aaagtgtctt
     6421 accccaatcc catagccata cctatcaatg ggggctggcg atacaattac gggaatatgt
     6481 tttatgtgca actggtaacg cagtatcttg tcacaacaga gtttgatgat gatacagtac
     6541 aagccatcat ggacgaagct ctgaaatttg aaggctggaa gtatgtctat ggcggagctt
     6601 ccccgactac ctcttttgat tgtagcggac tgacacaatg gacgtatgga aaagctggaa
     6661 tcaacttacc acgaacagca caacagcaat atgatgtaac ccggcatatc ccattattgg
     6721 aagcaaaagc cggcgatttg gttttctttc attctaccta taacgctggc tcttatatta
     6781 ctcatatcgg gatttattta ggcgataacc gtatgtttca tgcaggcgac cctatcggtt
     6841 atgccgactt aacaagctct tactggcaac agcatttagt gggagcagga cgaatcaaac
     6901 aataagaaag gacgattcaa tgatgaaatt cggaaaaaat cagaatacag aaaaacagac
     6961 accaaaggaa aagaaacctc gtgtctataa ggtcaatcct cgtaaaaagg ttgtgattgt
     7021 cctatgggta cttttaggac ttagtttcag ctttgcgata ttcaagcact ttacagccat
     7081 tgatacccat accattcatg aaaccaccat catagaaaag gaatatgtcg atactcatca
     7141 tgtggaaaat tttgtagaga actttgcgaa agtctactat tcatgggaac taaacgacaa
     7201 gtccattgat aatcgcatag aaaacctgaa agcatatctg acagaggaac ttcaagctct
     7261 gaatgtcgat acagttcgta aagatattcc tgtatcgtct tctgtaaaag gatttcagat
     7321 atggacggta gaagcagatg gcgacaatca atttgatgta acctacagtg tagaccaact
     7381 cattacagag ggggaaaata caaagaccgt ccactctgct tatatagtga gtgtctatgt
     7441 agacagtact ggaaatatgg tcctcattaa gaatccgacc attactagca taccaaagaa
     7501 atcagactat aaaccaaaag ctattgaaag tgagggtacg gttgattcca ttacaaccaa
     7561 tgaaatcaat gagtttttaa cgacgttctt caagctctat cctacagcga cagccagtga
     7621 actttcctac tatgtgaatg acgggatatt aaaaccaatc ggaaaagagt acatctttca
     7681 agaactggta aatcctattt acaatcgtaa ggataatcaa gtcacggtat cgctgacagt
     7741 ggagtatatc gaccagcaga ccaaagcaac gcaggtatct caatttgatt tggtacttga
     7801 aaagaacggg agtaattgga agattataga ataacaaata ttggtacatt attacagcta
     7861 ttttgtaatc acgtactctc tttgataaaa aattggagat tcctttacaa atatgctctt
     7921 acgtgctatt atttaagtat ctatttaaaa ggagttaata aatatgcggc aaggtattct
     7981 taaataaact gtcaatttga tagtgggaac aaataattgg atgtcctttt ttaggagggc
     8041 ttagtttttt gcacccagtt taagaatacc tttatcatgt gattctaaag tatccggaga
     8101 atatctgtat gctttgtatg cctatggtta tgcataaaaa tcccagtgat aagagtattt
     8161 atcactggga tttttatgcc cttttgggct tttgaatgga ggaaaatcac atgaaaatta
     8221 ttaatattgg agttttagct catgttgatg c
//
LOCUS       DACDLM010000102         8068 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.104, whole genome shotgun sequence.
ACCESSION   DACDLM010000102 DACDLM010000000
VERSION     DACDLM010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8068
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.104"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..884
                     /locus_tag="IV356_002621"
     CDS             <1..884
                     /locus_tag="IV356_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HAP9016245.1"
                     /translation="ISVPVALFSFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTY
                     NDYFQIGMIGMIVSLVVVLTVANISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVL
                     GVVLLDLQIILGFILAGIWALLFTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMT
                     LAMFNNSAAYASPYFSAIFGDWIPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILA
                     VVLAVNPTMSPAFLFPLFAITTIAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGW
                     IIGAILCLITFLLYGNA"
     gene            932..3061
                     /locus_tag="IV356_002622"
     CDS             932..3061
                     /locus_tag="IV356_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HAP9016246.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKNLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKAIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIESVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPHTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            3036..3725
                     /locus_tag="IV356_002623"
     CDS             3036..3725
                     /locus_tag="IV356_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016247.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKEIE
                     KRCTEYDLDYK"
     gene            complement(4133..4819)
                     /locus_tag="IV356_002624"
     CDS             complement(4133..4819)
                     /locus_tag="IV356_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP9016248.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(4955..5149)
                     /locus_tag="IV356_002625"
     CDS             complement(4955..5149)
                     /locus_tag="IV356_002625"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016249.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(5199..5639)
                     /locus_tag="IV356_002626"
     CDS             complement(5199..5639)
                     /locus_tag="IV356_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HAP9016250.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELEQLFQAYASLDDVNS"
     gene            complement(5643..6488)
                     /locus_tag="IV356_002627"
     CDS             complement(5643..6488)
                     /locus_tag="IV356_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HAP9016251.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVDWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLVANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAVYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            6637..8055
                     /gene="pepV"
                     /locus_tag="IV356_002628"
     CDS             6637..8055
                     /gene="pepV"
                     /locus_tag="IV356_002628"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HAP9016252.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
BASE COUNT         2481 a         1514 c         1714 g         2359 t
ORIGIN      
        1 gtatttcagt accggttgca ctgttctcat ttatgggctc gattatggct ggaatctttg
       61 ctaatatcgt caatttcaaa caatatcaaa cgatttatgc tggtttcaat ccagcggctg
      121 aaagctatac ttataatgac tatttccaaa ttggtatgat tgggatgatt gtaagcttag
      181 ttgtggtact aacggtcgct aatatatcaa tgaacaaaaa gaaacgctat gcaatggcag
      241 caaacgtacc agctgaaggt ggcgacgcac caatgatctc atggttagcc gtattattac
      301 cagttttagg ggtcgttctt ttagatcttc aaatcatctt aggttttatt ctagcaggta
      361 tctgggcatt gctgtttact ggaaaattgc gcggaggtta taaagaaatc tgtcgtcagt
      421 ttgcgaaatt atttacagat ggcgcagtcg atgttgcacc aatggttggt ttcttgatga
      481 ccttagcgat gttcaataat tcagctgcgt atgcttctcc ttatttttca gctatttttg
      541 gagattggat accgcaatca ccattagtct tggcaatcgt atttgctata ttgacaccac
      601 taggattttt ccgcggtcca atgaatctag tcggttcagg ctcagctatt ttagctgtcg
      661 tgttagctgt taatccaacg atgtcgccag cctttttgtt cccgttattt gcaattacaa
      721 cgattgctcc tcagcattta gatattacac aatcttgggt tgcttgggga ttaggttata
      781 caaaagtaac ttctcgagaa tatatgaaga aatccatccc aactggttgg atcatcggtg
      841 cgatcttatg cctgatcacg ttcttattgt acgggaacgc ctagtaaaca aaacgtcgat
      901 aaaaacgatt agataaatgg aggaaaagaa aatgaaacgt tttgtgcgaa tgggaattga
      961 tgttggcggt acacatacga aagcagtcgc aatcgataat gcgacgcacg aaatcatcgg
     1021 aaaatcttca gtgaaaacaa cccacgatga tgtccgtgga gtagctgcag gtgtcgttca
     1081 gtcttttcaa aattgtttgc gggaaaataa tatcagtcca gaagatgttg tgtttgttgc
     1141 acattctacc acacaagcga ctaatgcact gattgaagga gacgtagcaa aagtcggcgt
     1201 aatcgggatg gcaaaaggtg gattagaagg ttttttagca aaacgacaaa ctagattgaa
     1261 cgatatcgat ttagggaata agaaaaaaat agagattgtc aatgcattct tacctgtcaa
     1321 aaacttaaat gtagaccgtg tttcagaaac gatttcttct ttagaaagag aaagagcgga
     1381 ggtcttggtt tcttctatgg catttggagt agataatggg gaaccagaac gagttgttta
     1441 tgaagcagca tctgtgaaag cgatccctac aacgatggct tctgacatca caaaattata
     1501 tggattgaca agaagaactc ggacagcagc aatcaacgca tctattttac caaaaatgct
     1561 agatacggca acctcgacag aagactccgt acgagaagca ggggtcaatg tttctttgat
     1621 gattatgcgc ggagacggcg gagtaatgga aatcaatgaa atgaaaaaac gacctgtttt
     1681 aaccatgctt tccggtcctg ctgcatcagt catgggctct ttgatgtact tgagagcgtc
     1741 taatggtgtt tattttgaag taggcggaac aacaaccaat atcggggtca ttaaaaatgg
     1801 acgtccagca atcgattatt caattgtagg tggccaccca acatatatct cttcattaga
     1861 tgttcgggtt ctaggtgtgg caggcggttc gatggtacgg gctaatcagt caggaatcat
     1921 cgatgtcggt ccacgttctg cacatattgc cggtctagat tatgcagtat ttacggagac
     1981 agaaaaaatc aaaggtccta aggttgaatt tttctctcct aaagaaggag accctgctga
     2041 ttacgtcaag gtagtgatgg aagacggaga agaagtgact attacaaata catgtgcagc
     2101 caatgttctt ggattagtgc aagaagaaca tttttcttat ggaaatgtcc catctgcacg
     2161 aaaagccata caggcattag cagactattg tcatacgacg gttgaagaca tcgcagagca
     2221 gatcatggaa aaatcctatg ctaagattga atcggtgatt ttagaattgg cagacaagta
     2281 tcacttggag aaagatcaga tttctcttgt aggtgtaggg ggcggcgctg cctcattgat
     2341 tacttacttt agtaataaaa tgggtgtgaa atattcgatt cctgaaaacg ccgaagtgat
     2401 ttcttctatt ggtgtagcac ttgcaatggt ccgagatgtt gtagaacgta tcatcccttc
     2461 gccaagtaaa gaagatatac gatcgttgaa aaatgaagcg atgaataaag cgattgaatc
     2521 aggcgctaca ccagaatcga tcgaagtcca cgtagaaatc gatccacata cttcaaaagt
     2581 aacggctatc gctactggtt ctacggaagt gaaagcaacc gatctaacca aggagatcac
     2641 aacagaagaa gcactagagc ttgctgcaga ggatatgcga ttaaataaaa atgaagtttg
     2701 cttattggaa aatacacctt tcttttatgt atgcggcgaa cagaatcgtt caaaaaatgc
     2761 tggaagtctt cggatcatcg atcaaaaagg atttatcaag gtccaacgtg gacatgcttc
     2821 atgtatgaaa acaactgcag ccaattatat gacagctgtc gaacaacttt gggaagatat
     2881 ggcagtttat caaactgaat tgattgcccg accagaattt tatctctgct taggagcaag
     2941 agtctctgat tttacagcga cggatctgga acaactacag cttttgatgg atctggaagt
     3001 atctactatg gaaccggagg aagaagtgat cgtcgttgcc ggaaatatca aacaaacata
     3061 agttagaaga gttactaaac gaattacaac agatccccga agaaatttgg ggattctacc
     3121 agtttcggcg agatttattt tggaaaaaga ttcctttgtc caagcagaaa attcttatac
     3181 aacaatcaat cgattgtggt atcgaaacgg catgtagcat caaaaaaaag tacccttttg
     3241 ccgatgtagg agaaatctgt gaacaaatgg ctgttccaat cgtttcctgt gaatcagagc
     3301 aaataaacga acgaatcact tttgcaactt atgcagaaga tgaagggatc cgattgatga
     3361 cggagccgtt agaaaaatta aaatgttcag gactagcttc gatctctaaa gaaacagcgc
     3421 aagctttgat tattggacat gaactatttc accacatcga agcttctgtt aagggaattt
     3481 atacgcaaag cgaaaaaatt gtgctgtggc ggttgccttt ttatacacat caatcaaaca
     3541 ttcgtgcatt gagcgagata gcagcgatga gtttttcaaa agagatgaat caaagcgatt
     3601 tttcgcctta tgtattagag gcagtcttac tttggccata taatgaaatt cgtagccaag
     3661 ggatcttaga agaaataaaa gaaatagaaa aaagatgtac ggagtatgat ttagattaca
     3721 aataaagaga ctgtgacaaa agtcgtgtca cagtcctttt tttccgaata aacggtgttc
     3781 tcctgtcaac tcctcggtca caagtcaaaa tattcaacaa acatgagaag ctgttttttg
     3841 aaattgttcc ttgtgactcg gagatgaacg gcaggctcac gacctcttgg aaaaaggtgt
     3901 tcaaaagctt gcatctgcgg taataagaac agccaagtta aaaacataag aagctatttt
     3961 tacttggctg ttcttattac ttgatgcagg gcagcttttt cacaacctct caataaacgg
     4021 tgtgcaatca gctgaccctc ggtattagct caaaaaaaac ggcaaaatat gaggaactat
     4081 tttgccgttt atttctctaa tactcaggtc aaaacgctga ttccaaaacc tcttatttga
     4141 tgggtctgtc ctgaatatct tcaaaataat cggggtaatt atgaatcacg tattcttgct
     4201 cctcgataat catatgtaaa tgcatcgtgc aaagaaatcc gacttcatca aagttatgat
     4261 caatcattga ttgaagcatt gtctgatgtt catctaatac tcgaccccag tctaattctg
     4321 aaatcgtcaa acgtaaccat ctgaaacggt tcaagtgcgt actataactt tctagccaat
     4381 cccaaatttc tcgttttcca gcaatttcat aacaagttcg gtgaaaatca gtatccaaat
     4441 caaaaaaagc ttttttattt tgagcgatca ctgcctgatc ggtttgttct agtatttttt
     4501 ctagtttagc ttgatcttgc ttggtcattt tcgcactgca ttcttgcagg atcggttttt
     4561 ccaacttttc ccgcgtataa cgggctaatg aagcagatcg gatatcgatt tttgaaacat
     4621 aagtgccgga ctgtggaatg gtttttacaa gctcttgatt gcgcagttgg atcagtgctt
     4681 ctcgaatcgg tgtacgcccg atagctagtt gttcttctaa cactttatcg gagattttac
     4741 ttccgggtgc taactcggaa taaatgattt gtttacgtat agattcataa gcttgctgtt
     4801 gcaaattatt gataaccatt taaccttcct ttctatgcag atataatcta ttataacata
     4861 aatcgcttac aaatcgtgtg ggcataaaaa cacagtctgc aaaaaaagcc ctgataggca
     4921 tgcctattag agcctcgaaa agaaaaatat tgaatcaatc tggtcgtacc tcttggatcg
     4981 gtttgacacg accgccgatt cttttagcaa aagcttcgga ttcttttttg tctttgaaaa
     5041 tgagcagatt gtctaagttt ttttcccgag tgcgacagcc agttttatcg atgtaaccgt
     5101 gcattacttt aacgacatac atggggatca cctgcttttt tcttttcatt atacgaacta
     5161 ctcgacacaa tacaagaaaa atgcttagac ggtctttatt aagaatttac atcatccaaa
     5221 gaagcgtacg cttggaataa ctgttctaac tccggattga ctttgctcag cttcactaat
     5281 cgttgcgaat cagaaagtaa aaaacagtgt ttactactgc cagtagtttt taattttttg
     5341 tcttcagttc ccacaatttc gtagctaaaa tccaaccgtg ttcccgtata cttttggata
     5401 gttgggtgga tgctcacttt ttctccgtaa tggatcattt ctttatagct gcaatttact
     5461 tccagaacgg ggatgatgat cccagattct tcgatttttt tatagggaaa ccctagatgt
     5521 accaataagg ctacccgagc ctcttcaaac cagcggatat aattgctgtg atgaataatc
     5581 cccatttgat ctgtttcata ataaaaaggt tctcgcacat aacctgtaaa tttctccatg
     5641 actcatgcct cgttttccat tgatttttta caaaaataat tcatccactt cggaagtgct
     5701 tcgctgattt gtgtcggcaa aacaatatat tgttcttttg ccagctggtc tccaatgaaa
     5761 ctatgaagat aaacagctgc tgcaatcgtt tggtcatttt gaggaaactg ggctaaaaat
     5821 cctgtgatca tcccagctaa agtgtcaccc atgccgcctg ttgccatagc agcagaacct
     5881 aaaggattgg tgtagaagtg ctggtgacca taaatttttg tctcatgact tttcaaaacg
     5941 agcacagcac cgatttcctg ttgcttcttt ttgttttctt tatcccgttg ttcttgtatc
     6001 ggtagagaac tcaaccgttg ccactccatt tgatgaggtg taagtacagt ttgttcggga
     6061 tagggtagca aaagatgatt agcaacaagt aaacttaaag cagagccatc aatcaccagc
     6121 cattgttctt ttgattggtt ttctagtact tgtttgaaac gttccaaact cttagaagaa
     6181 gtacccaatc cgggaccaat caagagtaca tctgcttgct ttattacgga aagaaactgg
     6241 tcagtatccg tccaatctac aatcattgct tctggcagat gactgtgaag agcactccga
     6301 tttttttcat cagttactac agtcgtgaga cccgctccac tgtgtacggc agctaaagca
     6361 ctcataatga ttgctccgcc atattgttca ttgccgccaa tcaaaacgat acgtccaaat
     6421 gttcctttat gtgaaatctt tggacgaggt gtgatgactc ttttcactag ttgttcgttt
     6481 atcagcatcg aaaaacctcc ttttactcat tatagcgtat atttttttta gagaaaaaca
     6541 gataagaaaa ggaattgtca gattttttga actatttttt tctgtaattt gtggtatcat
     6601 gaacacgaag acttaaataa gtggaggatt aactttatga caattgattg gcaaaaagaa
     6661 gtagaagcac gtaaagaaga cttgcttgaa gacttgaaaa atcttttacg tgtcaacagc
     6721 gagcgcgatg attcaaaagt aacaccagat gcaccatttg gacctggacc tcgcgacgca
     6781 ttgaaacata tgttagctta tggcgaacgt gatggattta aagtaaaaaa tgtcgataac
     6841 tatgcagggc atattgatct tggcgaagga gacgaaacgc tagggatatt tggacacatg
     6901 gatgtcgttc ctgcaggaga tggctgggac acagatcctt atgaaccagt aatcaaggat
     6961 ggaaagatct ttgcacgcgg atcaagcgat gacaaaggtc caagtatggc agcttactat
     7021 gcgatgaaga tcattaaaga acttgacttg aaactatcaa aaaaagttcg cttcgtagtc
     7081 ggcagcgatg aagaaagcgg ctggggcgat atggcttatt atttcgaaca tgaagaagaa
     7141 ccagattttg gtttctcacc agatgctgaa ttcccaatca tcaatggtga aaaaggaaat
     7201 gtttctttag ctttacgctt caaaggcgac aatgcaggag attatgtctt gaaatctttt
     7261 gtttccggac ttcgcgaaaa tatggtgcca ggaacagcaa ctgcagcact tcaagtacca
     7321 agtgcagatg cagctatcgc gatggaagaa gcattttacc aattcatcga agcaaatcca
     7381 gtaagcggaa cgattgaagc ggacaatacg tatgtaaaaa tcgaattagt tggtaaaggc
     7441 gcacatggtg caagcccaca atctggtatc aatgcaggtt ctttcttggc attgttctta
     7501 gataactatg aattcctagg atctgctaaa caatttatcc atgtagcagc tgcttatgtc
     7561 catgaagatt tttatggaga aaaactagga gtcgcttatg aagatgaaaa aatgggcaaa
     7621 ttgacaatga atgctggact atttgctttt gaagaaaatg gtacagagga agcgaacttc
     7681 atcaatatga atttccgttt tccaaaaggt gtaacagtag acggattgca aagtgacatc
     7741 gaacaaacag tggggcaaga aggcgcaaca gttactcgag gtgctcgcgt aatggaacca
     7801 cattacgtac caatggatga tccattggtg gctacattat tgcaagtcta tgaagaccac
     7861 actggagaaa aaggctacga acaaatcatc ggtggcggaa cttacggacg tttgttgaaa
     7921 cgtggcgttg cttatggagc gatgttccca ggatatactg atacaatgca tcaagcaaac
     7981 gaatttatga gtcttgatga cttgttcaga gcaacagcaa tctatgcaga tgccatctat
     8041 cgtttggcga aataaaaata ctaaaaaa
//
LOCUS       DACDLM010000103         7960 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.105, whole genome shotgun sequence.
ACCESSION   DACDLM010000103 DACDLM010000000
VERSION     DACDLM010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7960
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.105"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            6..1058
                     /locus_tag="IV356_002629"
     CDS             6..1058
                     /locus_tag="IV356_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HAP9016253.1"
                     /translation="MNEKEVESLVEKQGYSNSDIYAELYYQYPIFLNVNEKYKKMKLS
                     SKLVYMLLKDRNRLSLKNNLYDENQKIFLIFEIKNLVEISGMSKNTILSALDELQKVK
                     LLVKRKNGFNKSKMQMFPNFYYLLKPVLCKDDVYKINKITHQENRQKNLIVQNLNYGT
                     NQYSVDNSKFELCDTSMKTRDKNNFADSSKNELELYKSYKDSKDIKESHNDDLLESLS
                     TKNNKLDEELIETFIEENLLKQIWGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAE
                     KEQKIQLKIIYEICNNKYFVDHVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNK
                     ALELIELQISEGIDKQ"
     gene            1134..1352
                     /locus_tag="IV356_002630"
     CDS             1134..1352
                     /locus_tag="IV356_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016254.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            1339..4017
                     /locus_tag="IV356_002631"
     CDS             1339..4017
                     /locus_tag="IV356_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016255.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSETVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPASAIQQKVQQDIEERKNAMHGQAKSAEELINQK
                     RHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKEN
                     PQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSS
                     STSQPKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDVRENVQSSTSSQGF
                     KTVDVRENIQKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKSR
                     RRFTYEDNELFRDTLNDPNPLFDNLLRNKRGGLSCN"
     gene            4008..4205
                     /locus_tag="IV356_002632"
     CDS             4008..4205
                     /locus_tag="IV356_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016256.1"
                     /translation="MQLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKNEIESNFKCCSLEKNVRG"
     gene            4209..4820
                     /gene="mobC"
                     /locus_tag="IV356_002633"
     CDS             4209..4820
                     /gene="mobC"
                     /locus_tag="IV356_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HAP9016257.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            4805..6196
                     /locus_tag="IV356_002634"
     CDS             4805..6196
                     /locus_tag="IV356_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAP9016258.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQK
                     QFSDREGDEKFIKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTI
                     SIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIE
                     NQQKRQQNFEMEF"
     gene            6412..6699
                     /locus_tag="IV356_002635"
     CDS             6412..6699
                     /locus_tag="IV356_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016259.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGVFGSKANMFRVMVSNLP
                     VLASPSNNKFNDPESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNK"
     gene            6719..7213
                     /locus_tag="IV356_002636"
     CDS             6719..7213
                     /locus_tag="IV356_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016260.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLINDTENPIRPQQW
                     SIENKDGEELYEYDMILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRENGYIVGL
                     PFTL"
     gene            7281..7595
                     /locus_tag="IV356_002637"
     CDS             7281..7595
                     /locus_tag="IV356_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016261.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDMIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSQTFEIDPDYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            7694..7939
                     /locus_tag="IV356_002638"
     CDS             7694..7939
                     /locus_tag="IV356_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAP9016262.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSDLMDRLQLTRQKN"
BASE COUNT         3088 a         1058 c         1512 g         2302 t
ORIGIN      
        1 tgacaatgaa tgaaaaagaa gttgaaagct tagttgaaaa gcaaggctat tctaattctg
       61 atatatatgc agaattatac tatcaatatc ctattttttt aaacgtaaat gaaaaatata
      121 agaaaatgaa actaagttct aagttagttt atatgttact aaaagataga aatagacttt
      181 cattgaaaaa taacttgtat gatgagaatc aaaaaatttt tttgatattt gaaatcaaaa
      241 atctcgtaga aatttcgggg atgtcaaaaa atacaatctt atcagcacta gatgaacttc
      301 aaaaagttaa acttcttgtg aaaagaaaaa atggcttcaa taaaagtaaa atgcaaatgt
      361 tcccaaattt ttattatttg ttaaagcctg ttctgtgcaa agatgatgtt tataaaatta
      421 ataagataac ccatcaagaa aatagacaaa aaaacttgat agttcaaaat ttgaactatg
      481 gaacaaatca atattctgtt gataattcaa aatttgaact atgcgacaca tcaatgaaaa
      541 caagagacaa aaacaatttt gctgatagtt caaaaaatga actagaatta tataagtctt
      601 ataaagatag taaagatatt aaagaatcac ataatgatga tcttcttgaa tcactttcaa
      661 ctaaaaataa taaattagat gaagaattga tcgaaacatt tattgaagaa aatcttctta
      721 aacaaatatg gggagaaagt attgtgaatt gcttaaaact ggctagcaat agtgattatc
      781 gtcaattcga caactggtac aaaaaattca aatatgcgat tagatctgct gaaaaagaac
      841 aaaaaattca actgaaaatt atctatgaaa tttgtaataa caagtatttt gtagatcatg
      901 ttagagaaca gctatcaatg actttacgtg acttgatacg aagagcaaaa acagatcatc
      961 gtatcaaaca aaaagacgat tatatctttg cttctctaaa aaataaagcg ttagaactaa
     1021 ttgaattgca aatcagcgaa ggaatagata agcaataaga atagaattga gtcaaatgaa
     1081 atggaggggt atctccactt catttgagaa ctttgaatat aggaggggtt attttgatta
     1141 aaaatcgttt aatagatcaa gtttggtgtc tagatcaaaa tacagatagt ctcgaattaa
     1201 tcgagactat ttgcttcaac actatagttc tcgatttaag agctgaaaat gataattgtg
     1261 taactcatgt cataattaat caaaaaatgg ctcagaagct ctctgagagc ctcagaaaat
     1321 gggctaaggg aggtaacgat gaaaataatt gaaaaaaaga ttgccaataa aaaaataaat
     1381 tggttggttg ttaattttct tgttctgata gctatgatta tttttacaag taatattgct
     1441 catgcgagta ttttcaattg gtttgatgac acaaaaagtc aaacagagtt tttgaataat
     1501 tctctttata gaccttacct aaaaaagtac aatggagatt tccttagtca gttcgggatt
     1561 tggctcggat gggctgtggt aaaaggcatg tttactgtga cagattcgat tcaaaatatg
     1621 attccagatg tgctggattt gttcaatttc attgaaagta cagggctaaa taatgtttat
     1681 caatcagccg taaatacaat tgtcattgga ttaatgatcc tttcattgat gtttgttggt
     1741 tacaaaatga ttactggaaa aggaacagtg gatttaaaat cggttggaat gaacgtagtg
     1801 atgtctatag cattaatact tttaatgcca accatgattt ctagtggtat tcaatttgct
     1861 aaaacatttt ataaggactc tactacgatt acaaattcag atgacggagt cgcttggtca
     1921 ttgataaaac aaggagtaac agatttagca tatattaata aaacagatca gtactcaagc
     1981 attgataaaa cggaggatcg aaataattta acacgaaaaa attttcaaca gacggatctc
     2041 acacaagtgt taacggataa agtgattgat aaattggaaa aagaaaatcc aattgcggac
     2101 aatcttcgtt atgaattagt tgaaaattct aataatgaat ttgttgctac aaagttttct
     2161 gacaacttct tatcaacatt ttctgatagc ttgaaatcag gctattaccg ataccaagca
     2221 aatctatggg ggatttcaat tgggttgaca gcgttagcaa tcgcctatgt gttcagcgcg
     2281 tttgtgatca ttacagcaat actagaactt gcatttaaac gtgtgttagg tgttcttgtt
     2341 tttgcaacag atattgagac aggacagcgt tcaaaagttg ttctatcaga tattctacaa
     2401 tgttacttaa ctgttgggtt tcaaggattt gggttatcaa tgtttgctat gtttatcaat
     2461 tttctgaact caggacaagg tatctcaaca aatattttta taaaaacaat tgcttatatc
     2521 tgtgccgttt ttgttttaat caaaggcagt gaaacagtca tgagatactt tggtgttgat
     2581 attggactca aagaaggcta tgggcaactt gcttctgctt ttggaatggg cgcaatgctg
     2641 tttagaaaag gatcaaatgg atttaatcgt gctaaaggaa gcggagaagg agaagatcga
     2701 aaaccagaaa agaatttcgg cgaaactcta tcaaaaaaag ctggcaaaac tggaagagct
     2761 ttgggatatg cccatgaacg tggattatcc ggtttagctt cagatggagc tacaatggct
     2821 agtgaaagag caacaaaacc atttaagagt atgcgtgata tagctaatga taccaagaat
     2881 aagtttaaag aaggtttaga tgatggtaca gtgtccgcta ttaataaaaa tagcaaacct
     2941 atgttagcta aaaataaaga agatgaaact ggaaaatatg ctgattccgt gccaacacgt
     3001 ctttcagata gaaaagatgg tgctaaagtt gaaaatgccg atagaattat gtctagttct
     3061 gaacgtatgc gtgaagcaat gaaaaataat gctgaatcga ataataatcc tgcaagcgca
     3121 attcagcaaa aagtccaaca agatattgaa gaacgtaaaa atgctatgca cggtcaagct
     3181 aagtctgctg aagaattaat taatcagaag cgtcatgaag cgaaatacac gcctgaagca
     3241 atgaatcgcg aggaaataat gttaaggaaa cgtgtagaag ggcggacagg cgctaatatt
     3301 gacggaaaag aagcgttgac caaagaaaga attcaagaag ctaaaaattc aaatacagga
     3361 ttagaaaaat tagtcaaaga aaatccacaa aattctacaa gtagtcatgg tggccgatca
     3421 gtagatgtcc gagaaaatat tcaaggttca ctgaatggtc atgttggacg gaatgttgat
     3481 gtaagagaga atttacaaag ttcttcaaat gctcaaggta ctaagacaat tgatgttcga
     3541 gaaaatctgc aaagtagcag tacaagtcaa ccaaaaacag tagatgttcg agaaaatgta
     3601 caaaattcta caagtagtca agggtttaaa tcagtggatg tccgagagaa tgtgcaaggt
     3661 agcagtgcaa gtcaaccaaa aacagtagat gtccgagaaa atgtacaaag ttctacaagt
     3721 agtcaaggat tcaaaacagt agatgttcgg gagaacattc aaaaagatag tggagaaatg
     3781 aaagaaaaaa cacaaaaaat caatatcgtt gaagacagaa agtcagcgaa aaaatttgat
     3841 tcaaatcatg aaacagtgat tattgatagt gaaatccgtg aaaatgataa gggatcaaaa
     3901 tcaagacgaa gattcactta tgaagacaat gagttattca gagatacact taatgatcct
     3961 aatccacttt tcgataattt attaagaaat aaaagggggg gattgtcatg caattaattc
     4021 taaagattag tacgcatgat ttcttagaac ttgacgaatt atgtgaatca gtaaagaacg
     4081 caacaaatga aaaaatcacg gtcactaatt atattgaact gatgattcaa gaagaattaa
     4141 agatgaaaaa tgaaatagag agcaatttca aatgttgctc tctagaaaaa aatgtgaggg
     4201 gataatcaat ggatgataaa caaaaaatgt acgaaaaaaa tcgcaaacat agtgaggcct
     4261 taaattttcg tgtcgataaa aagacttatc ttgaactgac attgattgca aaacaaaggg
     4321 gaatttctag agcagacgtt tgccgtgagc ggttaaaggg actcaaatat gaaccgccgt
     4381 tgttagctga agatgatagg gtagttttaa ccaaacagtt aaatcaaatt ggtaacaatt
     4441 tgaatcaagc ggtaaaggca ttaaatatca ttgctaaata ttttagagaa gaatctgaag
     4501 ataaaaaaga aaagagccta cattttagtt ttgatgctag ccgttacaac atttttaaag
     4561 atgaacttgc gaatagcata gcaaaaaagt tgatgattag ttatccagat gacatttttt
     4621 tggagtccaa tcggagtgcc ccctcttttt ttaaattatc agaagtagaa aaagaatatt
     4681 tcgaatattg gatagaaaag caaactagac cgggtacgaa agaagagtat tcccaaaaag
     4741 ttgatcggaa tttaattcac tcaattcaga ttattgcaag tttaaaagat gaggtgaaac
     4801 aactttggga gctactataa catcgaaagg acgcaagaaa aatttatcct cgctattaca
     4861 atatgcagct aatccttcaa aaaaagaaaa atgtgttgca gtctcaggaa taaattgtag
     4921 tgatgatagt gaggaagcac tgcaagaaat gaatttagta cgtaccaaga tgaataaatc
     4981 taaagatata gcacaagcgt ttcatgttat tcattcgttt gataagagta cttctaaaga
     5041 gttaagtatt gataaaatgc acgaaatagc tgtcgaattt gcagagaaag cttttccaaa
     5101 ttcgcaaatc attgttgcaa gtcacaatga taaagatcat tttcatagtc atcttgtcat
     5161 taataatatt aacatggaaa catgtaaaag gttgcgtatt gaccctaaag atttagaact
     5221 aatgcgaaaa attaacgatc aagtcctcaa tgaacatggt cttgaatcag tgaataatga
     5281 gtactatgaa aacttagaaa agagaaccaa tctttattca aacgatcctt ctaagatgaa
     5341 atatggaaaa attaattatc aagagtttgt gcaaaatgcg atcgaagcaa cgttggaaaa
     5401 atgcgaagtg aattcttttg aagatttttc ggatcatttg gcaaaagaat ataacattga
     5461 agtttatcaa ttttcaaaaa caaataacaa acttggctat gttctttaca aacaaggtgt
     5521 aaatttctat gagcgtagag gtgagttaat tactttagga agagataaac aatctagaaa
     5581 agaaaaaagt cagtatgtcg aacgtacttt tagtgcaaga aagttaggga aaagatattc
     5641 atttgaatct gtttctgaac aacttgaaaa gaatttagaa gaatcacata taaaaaattt
     5701 ttttaatatg gaaagagagc aagttatgtc gctaattagt ggagtaaatt acaaaactgg
     5761 tgagttaaat gtaccgtttg tggaattaga ttccatcgca caaaagcaat ttagcgaccg
     5821 tgaaggcgat gaaaaattca ttaaatatga tgacttcttg cgagaggtag acaagcattt
     5881 tgtaaataca atgtctttag aagatgatca agaatacacg attaaacttc atacggatgt
     5941 gaatcctcaa actttacgta gtgcgaaaag taaaacaatt tctattaaaa agactgatca
     6001 gaaagagtta tttctaccgg caaagggttt tgaaaattgt tctcatacac cttctgctaa
     6061 acagattcac tatcaaatca gtcgcataat gaatgacgat gtaaaaatgt atcgtgctaa
     6121 aaaggattat gaattcacac aacaaatgat tgaaaatcag caaaaaaggc aacaaaattt
     6181 tgaaatggaa ttctgaatgg gcttgttagt ggactttcca gttttttgcc tatgaagagt
     6241 tgcttggaaa gaagcagttt ttaggacata cgccagctac ccatctactt gccagtcaat
     6301 ccgccccgct cacgctaggc tactttctgg caagtcagat ggtgggtaaa tctctgaggg
     6361 agcaagctcc ctacagactc cctcccaaaa aaagaaaggt ggaagaaaaa aatgaactat
     6421 ccatatttta aagtctcggc ttcagaagaa actaaagaaa tattcaacaa tttttacaac
     6481 caaaacaaag gagtttttgg ttcaaaggca aatatgtttc gtgttatggt ttcgaattta
     6541 ccagtgttag ctagtccatc aaataataaa tttaatgatc ctgaaagcat taaatttgaa
     6601 caaaaaattt cagaactaga atcaatgata agtaatgaag taattgaaaa gctggatgac
     6661 attgatcaaa agttatcgta ttctctaaaa aacaaataaa aaacggagga gaaaaaagat
     6721 gtttaaagtt tacttcccgt ttcagtggct cgttaaagga attcttttag tgctactagg
     6781 attgattctt tttggaagtt atctaacaat taaagccaga cattttccag aagaaaagcc
     6841 aataaaaatt gtaacaaaag atttaaaaat aggtgaaact tatcaggcag atggggttga
     6901 actaacattt aaaaatattg aagtgaccga aaaaagaaat gaatttgcac aacatgatcg
     6961 tgtattacaa gtgacctata cacttataaa tgatacagaa aatccgatac gtccacaaca
     7021 atggtcgatt gaaaataagg atggtgaaga actttatgag tatgatatga tattggataa
     7081 tccagagtat attgaaagtg gcaaagaaga aacagtaaat tactattatg aattaccgat
     7141 tgaaaggcag gactaccaaa tcgtagtacg tagagagaat ggttacatag ttgggttgcc
     7201 atttacttta taagttttat tttgttagta gtttttaagg taatatcagt tttgtgattt
     7261 ttgaaaatgg aactgggaga atggctgagg aaaataaagt tgttccgttt gaaacattag
     7321 tgataaataa ggaagagttt gagcaacttt ttcttgattt ttttattcaa tatgacatga
     7381 tttatgattt tagttcgtca ctagatttat ttgaattaga agcagaaata atagaaaaca
     7441 gtcgagagaa gaatggtaaa atcattattt cagtagaaaa attcaatgaa ttattctcac
     7501 aaacatttga aatagatcca gactattatc aaccacaaga agtttttcga gagtttagaa
     7561 ataagattat tggttttagt caaactacaa aatgaaagct taataaagca agtgttgata
     7621 gaattattcc tcaacgcttg ctttatttta tgggcacttc ataatagagg tatagagaag
     7681 agaggtattc attttggata ctattactcc aacaaacttc aaagaaaata taggtaaagt
     7741 gttgcaagaa gtagttcatt caaattctga aatagaaatt actagggatt ctaaaaatgg
     7801 attgaacgat ggcgtcatta tgatttctaa gagaaaatgg gagttgttac aagaagaact
     7861 ttatttacaa cgaacgggta catgggctta tgtatctgat ttaatggata ggctacaatt
     7921 aactagacag aaaaattaag gtgtgtagac tagaagaaaa
//
LOCUS       DACDLM010000104         7640 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.106, whole genome shotgun sequence.
ACCESSION   DACDLM010000104 DACDLM010000000
VERSION     DACDLM010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.106"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            344..3178
                     /locus_tag="IV356_002639"
     CDS             344..3178
                     /locus_tag="IV356_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP9016263.1"
                     /translation="MAKRIDRIYMYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNS
                     SKDLNQLVREGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDT
                     KDIFAKIIGANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAH
                     HVIDEETELIVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLD
                     EIHRLPPEGQEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLGTFVRRI
                     PINIKLPAFEKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQL
                     KSNIQLVCARGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKIT
                     VAPNDTIMKIQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFY
                     KDHGFSFNADSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKK
                     INLGEERHTNDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLR
                     ANQASGRIGVVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNV
                     QEVDEGSGVILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDL
                     DMLHESLKNFRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNK
                     RQETELEVLALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVI
                     LDQLLMESELEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTT
                     GIGDEEYGFKINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLED
                     QIKVKVPIEEMYYLLRLVHNQLDKKEYTVP"
     gene            3369..3860
                     /locus_tag="IV356_002640"
     CDS             3369..3860
                     /locus_tag="IV356_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIB"
                     /protein_id="HAP9016264.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            3963..4952
                     /gene="manX"
                     /locus_tag="IV356_002641"
     CDS             3963..4952
                     /gene="manX"
                     /locus_tag="IV356_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HAP9016265.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            4985..5788
                     /locus_tag="IV356_002642"
     CDS             4985..5788
                     /locus_tag="IV356_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HAP9016266.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            5809..6723
                     /locus_tag="IV356_002643"
     CDS             5809..6723
                     /locus_tag="IV356_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HAP9016267.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            6806..7180
                     /locus_tag="IV356_002644"
     CDS             6806..7180
                     /locus_tag="IV356_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HAP9016268.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            7319..7564
                     /locus_tag="IV356_002645"
     CDS             7319..7564
                     /locus_tag="IV356_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAP9016269.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
BASE COUNT         2477 a         1263 c         1683 g         2217 t
ORIGIN      
        1 ataaaagttg tagtggaggc tacgaagttt actttgtctt tttacactta atattttttt
       61 gccaatttgg aatcaggatg ttttgataac tatcgttttc aattgatgga agctatattg
      121 tttgctatca gtgaaataat tatatggtaa acagtgttct ttttcttgtt tccattataa
      181 aaatcgtatc gggatttttc gttcttttaa attgaacatt tctatctatc cgcgtgttat
      241 caacaaaaca aaatcaggta aatagttgac gaaacagaaa taaatacata gtattatgtt
      301 ttgaagccta agtacaatag tctatagaaa aggagcgata ccattggcaa aacgcattga
      361 ccgaatttat atgtatgtca aagaaaaaac cgctcattta acaaaggcag aatatgatca
      421 aggagtaaca acacaggaaa ttgctgaagt gttagggatt cagcgaacaa atagcagtaa
      481 agatctgaat cagctagtgc gcgaaggaaa actgataaag acagacggac gaccagtacg
      541 ttacatatat caaacactcg ttacgcacgt aaagccagtt acaaaacatg tagtcagtta
      601 caaagaaacg ccggtctctg aagaaaaaaa tacactccaa atagatacta aggatatctt
      661 tgcaaaaatc attggagcta acggcagcat gaaaaattca gtggaacagg caaaagctgc
      721 gattttgtat ccgccaagag gattaaattg tttgattaca ggacctaccg gatcaggaaa
      781 gacttatttt gcacacgcga tgtatcattt tgcaaaagcg catcatgtaa tagatgagga
      841 aacggaactg attgttttca attgtgctga ttatgccaat aaccctgagc ttttgatgag
      901 tcatttattt gggtacgcaa aaggtgcttt tacaggcgca gatgaagaaa aaatggggat
      961 tatcgatcaa gcggatggcg gtatgctgtt tttggatgag attcaccggt tgccgcctga
     1021 aggtcaagaa atgatctttt actttatgga tcatggaact tacagtcgtc ttggggaaac
     1081 aacgaaatcc catgaagcaa atgtacggat cgtaggtgcg accacagaag acccaggttc
     1141 ttctctatta ggaacttttg ttcggcgtat cccaatcaat atcaaacttc cggcttttga
     1201 aaaacgtcct gcaaatgaga aagtcgattt agtaaaaatc atgattgccc acgaagcaaa
     1261 ccgcacgcag cgaaagattt ctttgacaga agatgtagca aaagcattga tcggcagtgt
     1321 gacctatgga aatataggac aattgaagtc aaatatccag ttagtatgtg cacgaggatt
     1381 tctaaatcat atgcaatcac ccgaaatctc gatcacaatc gatgatttga cagaagggat
     1441 tcgtagcgga ttgattcaat tagcaagcaa ccgcagtgca atggcagagc tttctaaaat
     1501 attggagcca aagataactg tagcaccaaa tgatacgatc atgaaaatcc aatcggactc
     1561 ctatgagtta ccttataatc tatatgatat catcggagat aaagcagctt tactgaagtc
     1621 ggatggtttg gatcaagaag caatcaatca tttcatttct acagatatca acatccatct
     1681 gaagtctttc tataaagacc atggtttttc ttttaatgca gacagcaaat tagcagaatt
     1741 tgtagatccg aaaatcatag aagtgaccaa tcagatttat gtaatggtca aaagatcttt
     1801 accatatgag tttcagcaaa actttattta tgctatgagc ttgcatatca gttctttttt
     1861 gaaaaaaatc aacttaggag aagaacggca tacgaatgat aacatccgtg agatggcttt
     1921 tgattttcca gatgaatatg ctgttgcgaa agaagtgcgt agttatatcg aaacgtattt
     1981 tcaagtggag attccagaaa gtgaagacta ttacttgacc gttctactcg tctcgttacg
     2041 ggcaaatcaa gcaagcggca gaatcggtgt agtcgttgca gctcacggaa acagcacagc
     2101 aagcagtatg gtccaagttg tccaacagtt gttagatgca gagaacgtac gagcagtaga
     2161 catgcctttg gatatggatc cgaaaacagc attggaccga attgaacgca atgtacaaga
     2221 agtagatgaa ggaagcgggg tcatactctt agtagatatg gggtcccttg cgtcgtttaa
     2281 ttcgcaaatt caaagagaca ctggaattcc agtacgtact gttgatatgg taacaacttc
     2341 tctagttttg gaaactgtac gaaaggtctc agtattaggg acagatctag atatgttgca
     2401 tgaatcattg aaaaattttc gaggttacgc agaaatatct tctgtagaat ctgttcagga
     2461 agcaaaacct attcataaga aaaaagctgt tttggctatc tgcgcatctg gcgaaggtac
     2521 agcacaaaga atcaaagaat tgatcgaacg agcggtaaac aagcgtcaag aaacagaatt
     2581 agaagttcta gctttgtcga ttgtggaagt gaaagaagaa ctgccagtta tccaaaaaga
     2641 atatcagatc atagctacta ctgggattac tgatttgaat atccaagccc catttattcc
     2701 tttagaacgt tttattgatc aaaatatcga agtcattttg gatcagttgc tgatggaatc
     2761 agaattggag gaaactgaat tcatctccct agatgaagag tcagctaaaa atacgtgtgt
     2821 tgagtttatc tctgataact tcatctttat taatggtagt aagttaatcg atccaatgtg
     2881 gcaattttct acacaaatct ctcagacgac gggaatcggc gatgaagaat atggattcaa
     2941 aatcaaccta gtgatgcaca cagcaggaat gatcgaacgt attattcgga atgaaccatt
     3001 gactgtggaa gaaaacgaat tgacaaatac aacgaatgat cctctttata gccaattggc
     3061 agcctcagtt gttctgttgg aagatcagat aaaagtaaaa gtgccgatag aagaaatgta
     3121 ttatctgcta cgtctagtcc ataatcagtt agataaaaaa gaatacactg tgccatgaat
     3181 acacaaaaac gatacacttt tatagtgtat cgtttttgtg tattggttaa gaatccttta
     3241 aattcaatta gtgtatcgta aaaaagttgg cacgcttttt gcttatagta gtgtgtgcta
     3301 ggaggtggtt gttcacacag aaatgatagg ggtttctgtg aagtagtgag gaagaaggag
     3361 ttttgcagat ggatattcga ttggcacgta tagatgatcg tttaatccac gggcaagtcg
     3421 caacagtttg gtcgaagcaa acaggtgttg aacgtatcat tgtgatcagc gatgtagtcg
     3481 ctcaagataa attgagaaag tttctactaa aagaagctgc accgccgggg atcacagcaa
     3541 atgtaataac cgtgcagaaa atgattcaaa tctatcatag tggattatta tcacgagcaa
     3601 aagtgatgct tttattcacc aatccccaag atgttgaagc ggttgtccgc tgcggtgtac
     3661 agttgaagtc gttgaatatc ggcggtatga gttttactga aggcaaatca atgattacca
     3721 attttgtttc agtaaatcaa caagatattg attcctttcg ttacttgaac agtcaagaag
     3781 tggagttaga gattcgaaaa gtacctgctg acaggaaaat ccttttgatg gaactactag
     3841 cgaaaatcaa aaaggtgtag caagaatggt tgttggaaaa ggtcaaataa ttctgttgta
     3901 atggttagca attattaata tttttgaatt tgttacaaca aaagtaaata ggaggtataa
     3961 atatggtagg gattatccta gcaagtcatg gacaatttgc tgaaggaatc ttacaatccg
     4021 gttcaatgat ctttggcgaa caagaaaacg tcaaagccgt gattttgaaa ccaagtgaag
     4081 gtccagatga cttgagagcc aaattggaag aagcggttgc ttcttttgat aatcaagacg
     4141 aagtgttatt cttagttgat ttatggggcg gaacaccgtt caatcaatca aacacattat
     4201 tcgaagagca caaagataaa tgggcaatcg tcagcggttt gaatttacca atgttgattg
     4261 aagcctacgc atcacgcttt tcaatggaat ctgctcatga aattgcagca cacatcattg
     4321 aaacagcaaa agacggtgta aaagtaaaac cggaagaatt agaaccggca gaagcaccga
     4381 aagcagcagt tgaagacgca caacctaaag gagcacttcc agaaggaact gtggtcggag
     4441 acggaaaaat caaatatgta ttagcacgtg ttgactcacg tctgttacat ggacaagttg
     4501 cgacagcttg gacaaaagca gtgcaaccaa accgtattat cgttgtttca gatgcagtat
     4561 caaaggatga tctgcgtaag agactaatcg aacaagctgc tcctccaggt gtaaaagcaa
     4621 atgttattcc tattagcaaa atgatcgaag tagcaaaaga ccctcgtttt ggaaatacca
     4681 aagcattgct tttatttgaa aatcctgaag acgtattgac agctgttgaa ggtggcgtag
     4741 acatcaaaga attaaatgtt gggtcaatgg cgcattcggt cggtaaagtc gttgtaagta
     4801 aagtattgtc tatgggacaa gaagacgttg aagcgtttga gaagcttgaa caaaaaggtg
     4861 tgaaattcga tgtacgtaaa gtacctaatg attcacgcga taacatggat gatattttga
     4921 aaaaagcaaa agctgaatta gcaaaagcgt aataaataat attaaaattt ataggaggct
     4981 tatcatgtct attatttcaa taattttagt cgtattagtt gcctttctag ctggtatgga
     5041 aggtattctt gatgaatttc aatttcatca accactagtg gcatgtacat tgatcggttt
     5101 agttaccggt aacctcgaag ctggtatcgt acttggcggt acgcttcaga tgatcgcttt
     5161 aggttgggca aatatcggtg ccgctgtagc accagatgct gcattagcat cagtagcatc
     5221 agcaattatt ttagttttag gtggacaagg tgttaaaggt gttccttctg cgatcgcgat
     5281 tgccgttcct ttggctgttg cagggttgtt cttaacaatg atcgtacgta caatcgctgt
     5341 tccaatcgtt catttgatgg atgcggctgc tgaagaagga aacatccgta aggttgaaat
     5401 gtggcacatc attgctgtat gtttacaagg ggttcgtatc gcggtcccag cagcagcgtt
     5461 gctatttatc ccagcacaaa ctgtgcaatc attccttgaa tcaatgccag catggttaac
     5521 agatggtatg gctatcggtg ggggaatggt cgtagctgta ggttacgctt tggtaatcaa
     5581 catgatggct acaaaagaag tatggccatt cttcgttatt ggtttcgttg tagctgcaat
     5641 ttctcaatta acattgattg ctctaggtgc tttaggtgtt gcattagctc ttatttactt
     5701 gaacctttct aaaatgggtg gttcatcaaa taatggaggc ggaagcaact ctggtgaccc
     5761 tttaggcgac attttgaatg actattaatc ttgaaggagg aaaataaaat ggcagaagaa
     5821 aaaatcaaat tatcaaaaaa agatcgttta gctgttgcgt ggcgctctac cttcattcaa
     5881 ggttcatgga actacgaacg tatgcaaaac ggtggctggg cattttctat gattccagca
     5941 atcaaaaaat tatacaaaac aaaagaagaa cgttctgcag cattaaaacg tcacttggaa
     6001 ttctttaata cacacccata cattgcttct ccaattttag gggttacatt ggctctggaa
     6061 gaagaacgtg cgaatggcgc gcctgttgat gatgtagcga ttcaaggggt taaagtaggt
     6121 atgatgggtc ctttagctgg tgttggtgac ccagtgttct ggtttacagt acgtccaatg
     6181 ctaggtgcac taggtgcttc attagctatg ggaggaaata tccttggacc aatcatcttc
     6241 ttcttaggtt ggaacattat tcgttgggca ttcatgtggt atacacaaga atttggctac
     6301 aaagctggtt ctaaaattac tgatgacctt tctggcggat tgttacaaga cgtaacaaaa
     6361 ggtgcttcaa ttttagggat gttcgtatta gctgcccttg tacaaagatg ggtatcaatc
     6421 aaattcttac cagttgtatc aactgtaaaa ttagataaag gtgcttacat cgaatgggat
     6481 aaattgcctt caggtggtga aggaatcaag agtgcatttg aacaagttaa taatggctta
     6541 gccctttctc ctgaaaaggt aacaacatta caagacaact tagaccaatt gattcctggt
     6601 ttagctgcat taggattaac attgttatgt atgtggttgc ttaagaaaaa ggtttctcca
     6661 atcgttatca tccttggttt attcgtagtc ggtgttgttg gacacgtcat cggactttta
     6721 taatccataa aaatatagct cgggcgttgt cccgagcttt ttttatatag tatactgttc
     6781 ataaacaaat atctggaggg agaaaatggt tcaatcaatc aatacaaaag tagacttggt
     6841 aattgatgct acttcgttta cgggtctgac agattacggg caaatcatga taggtgataa
     6901 tggttttgag ttttaccatg cgcgagatag acgcaaatat atccaaattc catgggaaga
     6961 agtggattat gtactagcat cagtcatgct aaagggaaaa tggattcctc gatatgccat
     7021 tcaaacgaaa aaaaatggta catacacatt ttcttccaaa gaacctaaaa aagtgcttcg
     7081 tgcgatcaga gaatatgtag atgaagatag aatggtacaa tcattgagtt tctttgatgt
     7141 agtgaaacgt ggtattcgta gtatgtttaa acgcaagtaa aaaataaaga aaacttctaa
     7201 gaggaggttt tctttatttt tttactttgc agaagaaaat atgaaatagc aaaaccaatt
     7261 atttgtcccc tttaaatccc atatgctaaa attgattagc aaagaaggag gttatattat
     7321 gagttggtta tggacattga ttgttggagc cgtgatcgga gcaattgcag gtgcgatcac
     7381 cagtaaagga aattcgatgg gctgtgtaac gaatatcatt gctggactag tcggttcaag
     7441 tattggacaa gcgattttcg gcgaatgggg accaaaagct gcaggtatgg cacttattcc
     7501 atctatttta ggcgcagtga ttttggtagc agttgtctca tttttctttg gaaaacgatc
     7561 ataagttttt acaaaatagt aaactaaaag gagttgcagc gagactgtga ctcctttttg
     7621 gctttattta tttaaaataa
//
LOCUS       DACDLM010000105         7584 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.107, whole genome shotgun sequence.
ACCESSION   DACDLM010000105 DACDLM010000000
VERSION     DACDLM010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7584
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.107"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..667)
                     /locus_tag="IV356_002646"
     CDS             complement(<1..667)
                     /locus_tag="IV356_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP9016270.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEIGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKR"
     gene            752..928
                     /locus_tag="IV356_002647"
                     /pseudo
     CDS             752..928
                     /locus_tag="IV356_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
     gene            complement(1104..1673)
                     /locus_tag="IV356_002648"
     CDS             complement(1104..1673)
                     /locus_tag="IV356_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAP9016271.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1747..2070)
                     /locus_tag="IV356_002649"
     CDS             complement(1747..2070)
                     /locus_tag="IV356_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016272.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2224..3036)
                     /locus_tag="IV356_002650"
     CDS             complement(2224..3036)
                     /locus_tag="IV356_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016273.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3390..4238
                     /locus_tag="IV356_002651"
     CDS             3390..4238
                     /locus_tag="IV356_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HAP9016274.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4383..5324
                     /locus_tag="IV356_002652"
     CDS             4383..5324
                     /locus_tag="IV356_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HAP9016275.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKTFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5314..7485
                     /locus_tag="IV356_002653"
                     /pseudo
     CDS             5314..7485
                     /locus_tag="IV356_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2262 a         1508 c         1360 g         2454 t
ORIGIN      
        1 aacgcttgtc atgaaaatct tgtgctccac ccttagtatt tccttctgga tcgtttgtcg
       61 cacgcatcat gacgtatact ttcttattag ggaaatcacg catattgaaa gatacatgat
      121 agccaacatt tcctaaagta ttataagctt gatttacgtc tggtctataa atcccatcag
      181 ctcttactct agctagttct tttccagtat tgtagtccat aatgaaaata tactcgtatt
      241 tataattagc aatgtgccat ccagctacat gcaagtttgc gttttcgatt tctccgaact
      301 gatcaatgtg ggcgtaattt gttccatctg tcagcgtaga atttgcagca cctgctcgag
      361 ttggatcaat tactggttta tcctccgaag tagttggatt atcatccgta aaaccatgag
      421 ccaaatcata ggctagtttt tctttactta cacctatttc agaaagataa ccgtaaggat
      481 ctgtatgatc gccccaaata ttttgtgtta cccataaatg cgatttgatt cctggttggt
      541 tataaggagt gtctaatgtt aatggaatac catatttcat tgctgaatct cttgccaatt
      601 caacgtatac tttatagttc ttttcaaaag tttctttatc atgtgtgtgt tgtaactcga
      661 tttgcacagg acttttggct cacgaggttg tcctactcta catcttgctg atagatatgc
      721 tgaaaggaaa acaccaacat tatgttttgc tttttcagct agaacgagac aagcaggaat
      781 acctttagaa gatatcaaag gttttttagg tcataaagat gtttccacta cacaagtcta
      841 tgcccatatt tctcccgaag tgaaaaaaag atcaatgaat caactagaaa actatataga
      901 agagcaaata aaaaagcact caaattgagt gcttttttaa gctcactatc actaaaacta
      961 tcactaattt tatttataag cgaacatgtt tctatcactg attttttaaa tctagcgaaa
     1021 aacccttatc ttaaaggcgt tcgttcaatt ctttggcaag gtcttcaaag cctggcttgc
     1081 ctagaagtgc gaacatggtt ttcttatagc tcatgtagaa aaattttctt gatgatgatt
     1141 ttatccatca attgagattg actgttttgc tctcctatga tttcagctat gattgtccga
     1201 ttttgcggtt ttcttcttaa ctggtagttg attttcccag tttccatcaa ctcgctaagc
     1261 atatccacga ctccgccaaa tccggtcttt ttcgtaataa aacctagtgc taccattcgt
     1321 tcatctagat tttttgctgt aatcgtcaca ccagtaatga gcgagtgctg taatgtttgg
     1381 gccagctctt ccatcccttc agcattggat acgacggaag ctgttttgtt aataggttct
     1441 tcgtttattt cttttggttc tttcctctcc actttcactg tttgacgaag gacatctagt
     1501 tcttgcaaga gcgtttcgta ttgttcttgg gtcagcatca cgccagctac tttttcacga
     1561 ttaaatatat atacgccagt tcccgcgtct cgcgcttgag caaatacatc catcggcgat
     1621 cgtttcactt ctgtgatcga agatgtggga acttctaatt tctttaattc caatggattt
     1681 cctcctttac taatcgcttt ttattatagc acagactgac ttgttttgat cttttttcca
     1741 aaggttttat cggtttttgc ctaaccagta attgatatcg gtaagaagtc tttcgatacc
     1801 aaatgaagga tggtacagat acgttttttg atcttcgtta tggtctagtg gaaaaaaatg
     1861 atcgatgatc actagatctg cataccgagg cggcttattt cgagtacata catgtataga
     1921 gatccgtttt cgatgtctta gcgttttgtt cagtacccca gcaagtcttc ttgcttcttg
     1981 gtgttcatag cgaaaaaaaa agacgatttt cacttcagga gggtggacat ctaaataccc
     2041 tcgttcctgg agtgttttca gtaaaagcat cccccactct actgcggggt gtgcaagtgc
     2101 ttgttggatc gctagccgaa attgatatag tttatctttg gaattgggaa atttttctaa
     2161 tgtttcctga taataacgaa cttcttctat cagccggtca tggataccaa ttacgtaacg
     2221 aagtcattct tggtaaagta cttttgtcag ctttgatttg ctttcgctct caaattcgct
     2281 attcagccaa aacagcgaat caagcttttc agtcacaatc gtcaatttcc gatagtcttg
     2341 tgtctcttct atccgtttcc accgcttttc agtaatctgg ttacagctca agcgcaaaat
     2401 tgctagataa tttttttctt ttattggcaa aatctgctcc tctctaaata gcaattcagg
     2461 aaacaattca aagaatagtg ttcgactgtc tcctaaaatc tcgatttctg ccggatcctt
     2521 tctttgcttc aataattgga tgaacatctc agaaaaggac tgctctccat catctgcaaa
     2581 aaaatgcgga aaatctttca aaaagcaaaa cagcagatat cttacttttc tttctgaacc
     2641 aaagatctgt gcttttttat aagaaaaaga aaggtggtac tcgccaaacc actttctcaa
     2701 tcgctcttgc gtagaacgat cgtacttctg ctcgtaaggt tcattcaata gcagattttt
     2761 cagtaaacaa aacgggggtg attggatcag aaaaacaaac aagagataag gttcgctata
     2821 tccttgatca taaactaact gaacggtttt cttatgaaga atcagctgaa tgggacagtc
     2881 gctttccgcc aaacgtttca gatgccgatc cactgtttta acatcgattt tcagttcttc
     2941 agctaaatca gcttttcgcc agatcaaatc tttcattaga ttgattagtg aaaataaatt
     3001 ctgtgcattt tttgataata gtttttgcca tctcatcgat catttctcac ctgatttcta
     3061 aacatattgt ttgatcaaaa tgggttcact cctaaaaaga taaaaaactc cctttctatt
     3121 tatttaaata cgcaaatctt cctcattatt ttttatttta ctcaatttaa tcgtattctc
     3181 atttcaaaac gaatgtactt taaaaaaaca taataagatc actttgcttg taggatgtat
     3241 tcccttccat tacaatgaaa taaatagcga ttttatgaga aggtgatgtg aaaatggaag
     3301 aaaaaataga agaatccaaa caaaaaatcg atcagttgat ataagaatta gaaaaagcgg
     3361 tcatcggcaa acgttcaact atccaattga tgatcgtggc cctattagca ggtggtcatg
     3421 tcttattcga agatattccc ggtgtaggta aaacgttact ggtcaaagca ctagcaaaag
     3481 ctgtacaggg aaccttcagc agagtccaat gtactcctga tctgctgcct agtgatattc
     3541 ttggtttttc cgtatacaat tcacaatcaa aagagtttga atttcgtccg ggaccgatct
     3601 ttaccacgat cttgttagca gatgagatca atcgtacgac tcctcgtact cagtcagcac
     3661 ttttagaagc aatggccgag aatcatgcaa cgatcgacaa caatacatac cctctagaca
     3721 atcatttttt tgtcttagct acgcaaaatc caatcgagta cgaaggaaca tatcctttgc
     3781 cggaagcaca gctcgatcgt tttttattcc gactacaaat cggttatcct tcttttgatg
     3841 acgaactttt gctacttttg gataaattcg aaaaagtgtt ggataactta aatgaagtat
     3901 tgaacagtta tgaaatagaa gaaataaaaa caaatgtggc gaatgtcttt gtcagtcccg
     3961 aagtggcatc ttatgccttg cagttagtgt cagcaacaag aagtcatgct gccatccagc
     4021 ttggcatcag tccacgagga agcctttcct ttattcaggc agcaaaagct tatgctttaa
     4081 tccatgggag aaattacgtc acgcccaaag atttgcagga tttagttcct tacgtgtttt
     4141 cccatcgcct gattttttac gatcgttcat tgaaggaaga cgaaaagaaa caaatcattc
     4201 atactcttgt tgcacaaatt cctattcctg tgaggtagat tgaggtagac aatggaaaaa
     4261 atcaaagatt atttcattaa ttttgtgtta tttctggtat atttcatcat tgtgcttttt
     4321 gctcttgtat tcaacaattc tttaggctgg ttcttgttgg ccttttttac tctttatgta
     4381 tcatggagct tgatttcatt aagcagcttt ctaaagaaac tttcggttac ttgtacattg
     4441 cagccactcg tttatcgcaa aaaaagtatg caggttattt tttccatagc aaaaaagaga
     4501 actttttctt tacctctccc tcgtttacaa atcggcttcc cagcaatctt tgcagaaaaa
     4561 aacaagagat tttgattctt acaaataaac cgcaagaagt ccaattgctt tggcagccaa
     4621 aagaaagagg atgccatgaa acattaactg tcatttttac agcctatgat agtctaggac
     4681 ttttcagaaa aagtgcaaaa agagagatct cttttcctgt gactgttctg cctgcttttt
     4741 gtaagattca agcagaaaaa ttacagagag ttctggaaaa aaaacagcag ctgaacgcgt
     4801 accaaagagg tcttgatttt cgggaacatc gcgcttatcg tccaggtgat tctttcaacc
     4861 gaatcgattg gaaattgtct gctcatactc aagagtggtt ataccgtgaa tacgattatc
     4921 aagaagaaga atgttctcct cttttttgct tttggggttc gcccagtcca aaatttgaac
     4981 ctctgctaga cttgtatttt tctttatggc atttgagaaa agaaaagcag ccggaacttc
     5041 tgatattagg caaccgcgcc tttcatggca aagaccccgg tcatacctat tttgcttctt
     5101 tggaagctgg cgatgagaaa acttttttcg cacacttgaa aaaatatgca aaaaaacaaa
     5161 tcgtcctctt tgttcctgag aattctcctg aagtctcaga agctattgaa acattgtcaa
     5221 aagatcgaac ggtttatctt gtttatttcg tagaaaaaca actcatggtc caagaaaaag
     5281 acaagatatg ttcattgcca ggaggtgaat ggattgacga ttaaacggga aaaatggctg
     5341 cgtggcgttt actcctttgt gatactaagt gtaggtgctc cgatatttgt agtagctaat
     5401 caattgcaaa acagctacct tcttatccta actattggtg tcctatgcct tattgtctgc
     5461 tgtattccta aaaaatgggt acgtttgctg ctttctttgc cagtaatgat aggttgtttg
     5521 tttttatatt ttccttcgaa gacattttcc atattatgga tcttacagtt tttttcgtca
     5581 gttacagagg aattcttcca tctatcccaa ggtaaacttt attatttgcc agaaaagaca
     5641 gctttttttc tcataatgtt gctgatctat ttatttatta cattgaccgt ggattacgac
     5701 tattggtacg caccctttct ttctttgatg gcttacttca tgatgcttac cgtttttcgg
     5761 aaaaaagatt tactgtacga aatgattgcg gtagtaactg ttttgttcgt gtatctggca
     5821 gcaaggcaat ttttctccat ccggttgttg tcgagaaaca ctcgattcca gtcattgact
     5881 acagttctgc ttatttgttt cttaactttt agcgctatct tgcctttata tcttccgaaa
     5941 gtacaccaat ctctcgagga aacgagtgaa ccgatccgag aatatcttaa tgatgaaggg
     6001 ctttatgaca cactccatga gtatcaatta accggaagtg caagaacagg cttcagtgag
     6061 aatgatgaac agcttggtgg acctttatat gataatggcg aagttgtttt tacagcgaac
     6121 caaaaaggaa atggctattg gaagatcgaa aataaaaatc attacaccgg ttctggatga
     6181 atagaagatc aggacgcacc catccaacca atccaagaat tccctgttga catcacgagc
     6241 taccaaaccg ttatagaaga caaagaaaac attacattga ccctaaaaaa acaagctttc
     6301 ttaccttatc cttatggaaa tactaccttg actgattttt cattagctag tggacaaacg
     6361 ctttactatt tgcctgaaag ccagcgattc attcctgtcc cgaatgaatc gacacgttct
     6421 gcaactttac aaacagaaag gttagttttt acgagagaag aattaaaaag cagtcagtta
     6481 aaagctgatg atttagaaaa tcagcagaca aatcttcaat tgccaaaaag tttgcctaaa
     6541 cgtattgagg acttggcggt cgaattgacc aaaaatgaag caactttaat tcgtaaagtc
     6601 gaagctgtct aacagtattt aaaaacaagc ggaaatttcc gctattccaa aacggatacc
     6661 gggcatactc caaaagaaca cgattatgtg gattatttcc tctttgattc aaaagtcggc
     6721 tattgtgaca acttttcaac ttctatggtc gtccttcttc gaacacttgg tatcccagct
     6781 cgctggacaa aaggttttac aaatgggctc agaacaggca cagataatca agggaatgag
     6841 gaatacagca ttctcaatag tcatgctcat tcttggccag aggtatactt tcctggattt
     6901 ggctggcttc catttgaacc aaccccttca tttgccaatc caatgggttc acaaccagtt
     6961 gctgaaacaa ccgaaaccgt ccagcctgct atcgaacaac caaatgaaag cgaaaatatg
     7021 gcagaaacta tttccagtga gagatctgag gtcattccat cagaagaaac aacactcaca
     7081 ccagcttata aaatcgtctt attcagcctt ggagtgtgtt tatccgtctt gttgttcttt
     7141 ctattgttat tcagaaaatc tctgcgctgg acaagttatc ttatctatct tcattttttt
     7201 gcttctacta atacgattgc atatcaaaaa cttcttaacc ctttggaaac attggtaccg
     7261 cgcaaacccg cagaatcttt gcaggaatat agcctgcgaa tagaacaaga attcaagcta
     7321 gatctgcgtt tcattcgatt aactactcaa tatgaagcag aaatatatgg acgacaagca
     7381 gatccggtaa aattcgataa aaaaacctat ttagaaataa cgcatataat aagaaaaacg
     7441 gtatacaaaa aaattctgac aaaagggagc cgcttcaaaa aataagataa aatttctgga
     7501 gaatctactt ctcgaatgcc gagaaccagc tgattgagta tcgattactc gaaaaaaagg
     7561 ttgtgacacg ttttttgtca caac
//
LOCUS       DACDLM010000106         7307 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.108, whole genome shotgun sequence.
ACCESSION   DACDLM010000106 DACDLM010000000
VERSION     DACDLM010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7307
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.108"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(39..2150)
                     /locus_tag="IV356_002654"
     CDS             complement(39..2150)
                     /locus_tag="IV356_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAP9016276.1"
                     /translation="MEGIMENKIHCTTGRVITLVLFLFLLLFARGTAVQALEKVDPSQ
                     IKENNNLVLYHDSDSLRNIEVTGINGFKILDEYSTKKQKVLAWPKVKDLKSTSKIVAH
                     YQKVGTYLGKEIDCDVTFSNFVAHAGVNQDGLAKTINGKKYYNYLLFDKNIYRGFFMQ
                     SINVMNAKLEFKYAGTKTKVALSEPQPEIQSKMRSMRAAGIDLNDTFLSIYSLNGQYQ
                     QRVSWYNDNNESVGERNIDMREFVGYEKMGSLPYFVTTDTACAEYKAPALSTNNLTSK
                     VVGGRAEKAYSSNDHFTDVVGADTYHRSGVTYTLQGASPTFMIGANTNSMMFSFDTAL
                     LWTPQPSKPTKEVFNKANTEEAAHNIDKKVIPQGSDVYYHIHQKFDALTVNTMNKYKS
                     FKITDTFDSKNFDMVSDGKNYDGALWYVEANGTWKKADTGGKLTVSGNTVTYTASDSF
                     LANAANYGRDYILQLHMRAKNDAKGIAPNVATVTFNNDPNKGTQKTNTVENYFSLKPN
                     KKVEQDGKDVDGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDIASDHYKQFSIQD
                     PVEDRLTYKEGSARVIDMSTGKDITSEGTLTYDSNSRTLKWEASADFLSKNLLDGREI
                     QLIFTAKTPLNEELDIDNQAKVSVESIEKATNVVTIGVKPNLPQIIVPKTGSNHLVLT
                     VIGSILFLTLASLGYVVLKLK"
     gene            complement(2439..3263)
                     /locus_tag="IV356_002655"
     CDS             complement(2439..3263)
                     /locus_tag="IV356_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016277.1"
                     /translation="MNKRKWLFVCVAALFSTVAYSQLSFADSSDSSTTQTIDNSITAP
                     SETDSSENTTEETADSNISFTESTNPTSESSSETSEKPQDVEDTQVIKQAIHIQKIIS
                     SNQINNQGSQVAQQEGINGAKFIVYDITNILEEMSQDDNEKNQSVEIIESKLKDRAKK
                     LSYDQLKKVAEGETKTIDDQEGVIEFSIEVPANKKQAYYIVNESSPENISNSEDIVLL
                     TPVSNEKGEFLTDVWLYPKSEKSEPKEEIKKVVSTGVKKNFFENCWEFFAQLFFDN"
     gene            complement(3260..4015)
                     /locus_tag="IV356_002656"
     CDS             complement(3260..4015)
                     /locus_tag="IV356_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP9016278.1"
                     /translation="MIIRKPPKRRVMHKLMIFFWLLSAVAVYLIPVVETNVAKFQQQQ
                     RILAIENLEKTDSSLDVAKIELGDPVGVLTIPSISLKLPIYDGTSDKILENGVGITEG
                     TGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGQKFFIKVNEEQHAYQIYRIEEVK
                     AEELQKNYLDYLMPEKDQDRITLMTCTPKGVNSHRFLVYGERVSFSKEDLKLQKKAKN
                     RKSISLDWRLALLFAFFCVPIIFIYKKIRRRSE"
     gene            complement(4028..6004)
                     /locus_tag="IV356_002657"
     CDS             complement(4028..6004)
                     /locus_tag="IV356_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAP9016279.1"
                     /translation="MAINRYVKKAGMLVGMLGIIAGCFQGYQVHAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PREDSDLTNAKVDEIVQDVEDKGSNSEYVKNATNKITSAVDENGEITFTDQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDKTGSGFLKNIHLYPKNIVSKLSFELTK
                     FGDDGADQSKQTLLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GKGLSYVAEKADIKVTNNDGSVVLKENTDYKIENSDSGFVIDFIVNNGQVSDTVANLH
                     GQDLKMTYNMFVNDSAEIANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLTDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGDYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQSYVLISCLLLGAGGLSAVVYFKKKA"
     gene            complement(6057..6728)
                     /locus_tag="IV356_002658"
     CDS             complement(6057..6728)
                     /locus_tag="IV356_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAP9016280.1"
                     /translation="MKKWLFGFLGVTLIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPGYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            complement(6788..6997)
                     /locus_tag="IV356_002659"
     CDS             complement(6788..6997)
                     /locus_tag="IV356_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016281.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKTMKQKHLKRLSVAQYINDMQLT
                     GKEKACLLGSMKNFEQLRRTYRIHF"
     gene            complement(7064..7303)
                     /locus_tag="IV356_002660"
     CDS             complement(7064..7303)
                     /locus_tag="IV356_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016282.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKEVFKALSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
BASE COUNT         2014 a         1497 c         1102 g         2694 t
ORIGIN      
        1 aaagaaaaca aggctgattc tcagccttgt ttttatattt atttgagttt taaaactaca
       61 tagcccaatg atgctaaagt aagaaataat atacttccaa taacagttag cactaaatga
      121 ttcgatccag tttttggcac aatgatctga ggtaagttag gttttacccc aatcgttact
      181 acattagttg ctttctcaat actttctact gaaacttttg cttggttgtc gatatccaat
      241 tcttcattca aaggagtttt agctgtaaat atcagctgaa tttctcgtcc atctaaaaga
      301 tttttactta agaaatcagc ggaagcttcc cacttcagcg ttcttgaatt gctatcatag
      361 gttagtgtac cttctgaagt aatatctttt cctgtactca tatctatcac tcgcgcagaa
      421 ccttctttat acgtcaaacg atcttccact ggatcttgaa tactaaattg cttgtaatga
      481 tctgaggcaa tgtctacacc ttttgtatgc catttttgtg tgactagata ttgtacttca
      541 gatcctgcat ttaaaggagc tgtaggcgtt ccttttttac catcatttcg accatcaaca
      601 tctttcccat cttgttccac ttttttattt ggtttaagag agaaatagtt ttctactgta
      661 tttgtttttt gtgttccttt gttcggatca ttgttaaacg ttacagtagc cacatttggt
      721 gcaattcctt ttgcatcatt ttttgctctc atatggagct gcaaaatata atccctaccg
      781 taatttgcag cgttagctaa aaagctgtca gaagcagtat aagtgactgt attacctgat
      841 acagttaact ttcctcctgt atcagctttt ttccaagtac cattcgcttc aacataccac
      901 aatgcgccat catagttttt cccatccgat accatatcaa aatttttgct gtcaaaggta
      961 tcagtgattt taaatgattt gtatttgttc attgtgttga ctgttaatgc atcaaacttt
     1021 tggtgaatat gatagtaaac atctgatcct tgtggaatca cttttttgtc aatattgtgt
     1081 gctgcctctt cagtattagc tttgttaaac acttcttttg taggcttcga tggttgtggt
     1141 gtccatagca atgcagtatc aaagctaaac atcatactat tcgtatttgc gccaatcatg
     1201 aatgttgggg aagcgccttg aagcgtatac gttacaccac ttctgtgata agtatcagct
     1261 cctacaacat cggtgaaatg atcattcgag ctataagcct tttctgcacg tcctcccact
     1321 acttttgaag ttaaattgtt tgttgataac gcaggagctt tgtattctgc acatgctgta
     1381 tctgttgtga caaaataagg taagctaccc attttttcat acccaacaaa ttctctcata
     1441 tcaatattac gttcaccgac agattcatta ttgtcattat accaagacac acgttgctga
     1501 tactgtccat ttaaactgta aatggataga aatgtatcgt ttaaatcaat accagctgct
     1561 ctcatcgatc tcatttttga ttgaatttct ggctgtggtt cactcaaagc tacttttgtt
     1621 tttgttcctg catacttaaa ttctagtttt gcattcatga cattgattga ctgcatgaaa
     1681 aatcctcgat aaatattttt atcaaagagc aaataattat aatacttttt gccattaatt
     1741 gttttagcta atccgtcttg gttaacccca gcgtgcgcta caaaattaga aaaagtcacg
     1801 tcacaatcaa tttcttttcc tagataagta cctacttttt gataatgggc aacgattttt
     1861 gacgtacttt tcaaatcttt gacttttggc caagcaagta ctttttgttt tttagttgaa
     1921 tactcatcta gtatcttaaa tccattgatc ccagttactt cgatatttct caatgaatca
     1981 ctatcatgat aaagcaccag attattattt tctttgattt gactcggatc aactttttct
     2041 aaggcctgga ctgcagttcc cctcgcaaaa agaagaagga acaaaaacaa cactaaagta
     2101 attactcttc ccgtagtgca atgaatttta ttttccataa tgccctccat ctaatatttt
     2161 tttaaacgat cgtaagcttt tcattctttt tttcctaata cccacgttac caatcctgta
     2221 agaagaacca aactaaccat aaaaattgga ttgatcaaga gctttttaat cacctctaat
     2281 ggcatggaag cacattgaat gtttagaaaa tgaatgaaca atcgttgata tcttggataa
     2341 attgataatt gagaaaaaat taaaccgcaa cacaatattg ttgcggctaa aaaggataga
     2401 ttaaaaacta atattcttat tattttcatc atttcatcct aattatcaaa aaataattga
     2461 gcaaaaaatt cccaacaatt ttcaaaaaag ttcttcttta caccagttga cacaactttt
     2521 ttaatttctt ctttcggctc tgatttctct gatttagggt ataaccaaac atccgtcaaa
     2581 aattcacctt tttcatttga aacaggtgtc aataaaacaa tatcttcact gtttgaaatg
     2641 ttttcagggc ttgattcatt aacgatatag tatgcttgtt ttttgtttgc aggtacttca
     2701 atggaaaatt caatcacgcc ttcctgatca tcaatcgttt tggtttctcc ttcagccact
     2761 tttttcaact ggtcgtatga aagttttttt gctcgatctt tcaattttga ctcaattatt
     2821 tctacagatt gatttttctc attatcatct tgtgacattt cttctaagat attcgtgata
     2881 tcgtagacaa taaacttcgc gccattgata ccttcttgct gggctacttg actgccttga
     2941 ttgttgattt gattcgaaga aataattttt tgaatatgaa tggcttgctt gatcacttgc
     3001 gtatcttcta cgtcttgcgg cttttctgaa gtctctgaag aactttctga cgttggattc
     3061 gttgattcag taaagcttat atttgaatct gccgtttctt ctgtagtatt ctccgaactg
     3121 tccgtttcgc ttggtgcagt aattgaatta tctattgttt gagtggtact actatcactg
     3181 ctgtcagcga aagacagttg cgaataagct acagtagaaa agagagctgc tacacaaaca
     3241 aacagccatt ttctcttatt cattccgatc tcctccttat ttttttataa ataaaaataa
     3301 taggaacgca aaaaaaagcg aatagcagtg ctaatcgcca atccaatgaa attgatttcc
     3361 tattttttgc ttttttctgt agttttaaat cttctttact gaaggaaact cgttcaccat
     3421 acactaaaaa gcggtgtgag ttgacacctt ttggtgtgca tgtcattaac gtgatcctat
     3481 cttggtcttt ttcaggcata agataatcta aataattttt ttgtaattct tctgctttaa
     3541 cttcttcaat tcgataaatt tgataggcat gttgttcttc atttacctta ataaagaatt
     3601 tttgcccttt ttttactgaa ggcaaatcat cgaaaagatt atctttataa agtccactgt
     3661 gccccgcgat taaaggattt ttaccgtttc ctcctgtaat atcgccagtt ccttccgtaa
     3721 tccctacacc attctctaaa attttgtcgg aagttccgtc ataaattggt agttttaaag
     3781 aaatacttgg aattgtaaga acaccaacag gatcgcctaa ctctattttc gcaacatcca
     3841 aagaagaatc tgttttttca agattttcaa tggctaaaat tctttgctgt tgttgaaatt
     3901 tcgctacatt tgtttccaca actggaatta aatagactgc tactgccgac agcaaccaaa
     3961 aaaatatcat cagtttgtgc atgactcttc tttttggggg cttacgaata atcattagct
     4021 gatccttcta ggctttcttc ttaaagtaaa caactgcaga aagtccccct gctcctagca
     4081 acaagcaaga gatcaatacg taagattgga aaccgttgct accagtcatt ggtacggaag
     4141 ctttttgatt atttttgatc gtgattcggt tttcttcttt gtatgaatct ttgtctactt
     4201 tgaaagagat ctcttttgtt aatttttgat agttttcagg agcttttgtt tcttccagtg
     4261 agtaatctcc ttcagttaaa ccagtgattt caaaatgacc ctctttatct gattttagga
     4321 ttgctgcatt tgctacatcg tctacccaaa ctgcttcttt gacaccatct ttatctgtat
     4381 cagtaagtcc accgtagtac ttaccttctg cattcttagc tgcaaattct gcgccttcaa
     4441 gcggtgttgc tttgatacct gttccaaata ggccgctatc gacttttaag aattttgcgc
     4501 cataagtcac aacgtcagct ttcgtttttt cgtggtgttc ttcctgatta aatggattat
     4561 tgttataaac gaaatccacg ctatttgtta atggatttgc gatttcagca ctatcattca
     4621 caaacatgtt ataagtcatt tttagatctt gaccatgtaa attcgcaact gtatcactta
     4681 cttgtccatt atttacgata aaatcgatca caaaaccact atcagaattt tcgattttat
     4741 agtcagtatt ttcttttaat acgactgaac catcattatt tgttacttta atatctgctt
     4801 tttcagcaac ataagaaagt cctttacctg ctgtatctcc ccatttaaat acactgtaag
     4861 gagaagtttc gcttttcaca ccgtttactg tgataccgtc tgcgccacct gcaatgtctg
     4921 ttggaatatg aatcgttcct tgataattta ctgcgtcacc aatttggaaa gaatgttctt
     4981 gtcctgttcc atttgttact gttttatcga tcactggtgc tttatagttt acgtatgaag
     5041 cttttaagtc acttgtcacg ccatcattcg taatttcaaa ggttaattta ttgtgcgcat
     5101 cgttgcgagc gtctgcgcct aataaatatt gatctgctgt tggttcttga tctgatccca
     5161 ctacaacttc cgaaggaact tccacaaaat agtattttcc taacgtcaaa tcagtcgcag
     5221 tcagctttcc ttgatcatcc gatacaagat cacccaattt tgttcctttt ccaggttcgc
     5281 ccttgtataa ctcaaatttt gcccctttta aaagggtttg tttgctttgg tctgcgccat
     5341 cgtcaccaaa tttcgttaat tcaaaactca acttagaaac aatgttctta ggatacaaat
     5401 gaatattttt taaaaatcct gatcctgttt tatctgtcat tggcgcaatc acaaccattg
     5461 gttttgcttt ttgtgtgact aatccagcag cggatttact ttcataaacc acatatacat
     5521 tccctttgga attgacatag gctggttgat cagtaaaagt gatctcacca ttttcatcta
     5581 cagctgaagt aattttgttg gttgcattct tgacgtactc actgttagat cccttgtctt
     5641 ctacatcttg tacaatctcg tccactttcg cgttggttag atcagaatct tctctcggta
     5701 atacttgatc cgtaatattt cctaacgtaa actcaacatc accataatct gccttgttgt
     5761 atttcgttac acctgtagga tattgatcgt gcgtataacc atcgtttttg atcccgtcaa
     5821 tatcaacatt caattgcgtt ccttgatcgt acattaattt atgaaccgtg atattgacct
     5881 tctctggtgg tgttttttgc gtgacatctt ctgcatgtac ttgatacccc tgaaagcagc
     5941 ctgcaatgat tcctaacatt ccaacaagca ttccagcttt ttttacatac cgatttattg
     6001 ccatttttta ctctcctcat ttcatatttc aacgactcgc gttgattaaa accttgttat
     6061 tgtagctctc cctgtaccac gtatctttct tttccttgtg acgtataaac acaagtaaac
     6121 aacgttaata agggtttctc tcctttcttt ggcaaagaca agaaagagtt ctcttcagga
     6181 acgccatcga ttaatttaaa gtacccaggt acgataaatt tacgcgttac cttgtaacga
     6241 tagacgccat cgttactaac taagtccatc acctccccta atgacaactt ttgaatatca
     6301 gaaaataaaa cacctggcat ttccatgtta tgacctgcta ggacatagtt tcctttgccc
     6361 atttcggcat cttcataaaa ataagtagcc gctccaagac tcaaagtgta ttgatttgcc
     6421 cctttaaaaa ttggcaatgc taaaccaagt gcaggaatct gaatttgtgc aaatacttgt
     6481 ttattgacgc ccatttcgat tgcttctttt tgtatggaca acatttgccc caaagacata
     6541 tcattattga cgttcgttgc atcctcctta taactctttg catgtgcatt gatttgatct
     6601 acgggcatct ttttttctat attttgctta aacacctctc cttcatgttt ttggtagcta
     6661 acatagccaa acacactgca aaagacgatt aaagtgactc ctaaaaaacc aaataaccat
     6721 tttttcatcc atctgcctcc tttcagacaa aacaaaaaaa ctttttctca tttccataga
     6781 aaaagtttta aaaatgaatt ctataagttc gtctcaactg ttcaaagttt ttcattgaac
     6841 ctaacaaaca agctttctct tttcctgtta actgcatatc attgatatat tgcgcgacag
     6901 ataatctttt aaggtgtttt tgcttcatcg tttttagtaa cttttcttcc atttctttcg
     6961 acactttttt tctgttttcg atttcttcat aattcatgag ttttcctacc ttccttgttt
     7021 tttgcaaaaa taaaaaagcc tatgatcaca tacgctctac acttcagtct tgggttatct
     7081 ttttctttcg tttaattact ggccgtgctg gtttcaaatc cttgattcca ttatgggttc
     7141 tccaataatc gaattctttt cgcaatcttt ctttttccat atctgttcct ttagataagg
     7201 ctttgaatac ttctttaggt gaataaccac gagctaacag ctgtacatac cttccttttg
     7261 tcaaagtatc catatccatc gcctctaaaa ctggtcgcgc catctac
//
LOCUS       DACDLM010000107         7016 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.109, whole genome shotgun sequence.
ACCESSION   DACDLM010000107 DACDLM010000000
VERSION     DACDLM010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7016
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.109"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(717..3866)
                     /locus_tag="IV356_002661"
     CDS             complement(717..3866)
                     /locus_tag="IV356_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HAP9016283.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDSQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDGVYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNEKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKTLMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSSEQINRMIDQMEPVKKESYLDPAVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQLIREGRTM
                     EDPDFPRIAITYSLEENSRDSSAQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(3879..5078)
                     /locus_tag="IV356_002662"
     CDS             complement(3879..5078)
                     /locus_tag="IV356_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HAP9016284.1"
                     /translation="MSNDTRPEIRFPGFTEDWEERKLIDLVVRLNKSTNSSRLPKVEF
                     EDIVAGEGRLNKDVSQKFDNRKGIEFLPNDILYGKLRPYLKNWLKATFTGVAIGDFWV
                     FRAKKSDSDFIYSLIQADRYQKAANDTSGTKMPRSDWKKVSDTVFYIPNDLKEQQKIG
                     IFFKKLDDTIALHQRKLDLLKETKKGFLQKMFPENGAKVPEIRFPGFTEDWEERKLGE
                     LGKTQSGIGFPDAEQGGSEGTPFFKVSDMNNIGNEYEMRNANHYVSNEQIERKKWKPI
                     KDVPAIIFAKVGAAIMLNRKRLVTSPFLIDNNTMAYLFNNTWDIYFGKILFETINLPR
                     YSQVGALPSYNSSDIENISVKVPVKDEQQKIGTFFKQLDDTIALHQRKLDLLKETKKS
                     FLQKMFV"
     gene            complement(5068..6663)
                     /locus_tag="IV356_002663"
     CDS             complement(5068..6663)
                     /locus_tag="IV356_002663"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HAP9016285.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAIAPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVDVLEHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLATFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEMWLQGALEVFKHEQ"
BASE COUNT         1995 a         1431 c         1122 g         2468 t
ORIGIN      
        1 gactaataca ggtagtcctc ttttttgtta ttttgatatt ctaaatcatt ttttattgga
       61 ttattccctt gttcgatata gacccaaatt gatctatcaa taattatcaa actgagtcat
      121 atagagacaa aaatttcaaa aatgacctgt taaatggtca tcgaatatca tttaaaatca
      181 atacgacgga gtcagacacg gagtcaaaac aagcccgctg agagtaaaaa atatatacag
      241 tcccataggt aaagtgccac aggactgtat atttttttat ttgagattac ctgaaatgat
      301 tccatttact ttttatctca ttttttccta ctagttagta tcaaatactc tcctattttc
      361 tcaataaact attttgggtt acatggtatc tgaaacagct aaaaccttgt cattacagca
      421 aaaaatcact ttatctccgt ttcatttcag atacatttca cttaagcgga ttccaaaaaa
      481 acaaaagaaa aaggaacccc tagttagcct atgcttttta ttggttcctc tcaaaacacg
      541 gtcatataac aacggggtgg ggtaaatgaa tgaaaaaggt ggaggaaaca ttattcaata
      601 gctgtcttaa atacttcgtt ataaaatgtg aacaaataaa agacatctat ccctattttc
      661 tacacttcca ctttactacc atctttgaat cgtacaattt tcttaactct tctcgtttac
      721 ctcaattcat tttcaagtgg aatcagctca tcatctaaca ttttacgcca tgctcgcttc
      781 atttcttgtg ggtatttaaa tggcttcgct tctggatggt tggctttata tccttcgtaa
      841 tccttactgt tgataattgc tttcatatta ggaattggat cttcacctgg catatattgc
      901 agattagaag catgtaattc tttctcagaa acaaaccact cattggaaaa gacatgaatc
      961 aaatcatcac tcgcttgtgt aaaatagcga cgtttaatga caaagatatc ttcattacta
     1021 tctaaagtcc ccacatcaaa cgcatttaaa atttgtcggt aaacttcttt gactccttct
     1081 gttttattca atttagccaa agctttttca atttcttctc gtgcatctga actattcgcc
     1141 gcataagttc ctagtaattg atcaatataa gtagaatcaa tatcatacaa cttcgtggta
     1201 ttttcactat aaaattcgat cgtggaaaaa tcttctccct ctttttctgg ttcttcctct
     1261 attaatgaac ccttcacggt ctcgtacacg ccaatttgtt cttccaaaag ttgaatttga
     1321 ttgttcaagg ttgaagattt caccatgtca tcattgtaat cgtcataagt cactaacgat
     1381 tcataagcac gattcaattc ttggaatgct ttgacgtact cgatacggat ttcaagtggc
     1441 gtatgttcat caatggattc catggatgaa acctctttta acttaccata tgcttgcttg
     1501 aatctttttt tggattcctg ataacttgga taaatcaaac ccgattcttc ttttgcttct
     1561 gaatacagtt ttgtcgcatc ctcgacattc ttctccattg tggctggctt tcggaaagta
     1621 acaattagtc cttttgtttt ttctggatac gtacggttcg tacgtgaaaa agcttggatc
     1681 aatcctgcat actctagatt acgatccaca aatagggttt gaatcgtagg tgcgtcaaaa
     1741 cctgtcaata gacgatccac tacgatcact aaatcaattt gtttcccaaa ttgtttgaat
     1801 tccgctcttt ttcgtgccaa acgattattg atgtctccgt tataacgctc aatgtctgct
     1861 aatgaccagg aagtatcata atactgatta tattcctcaa taattttttg catttcttct
     1921 tgttgggcac ttgaatctcg gctattttct tctaatgaat aggtaatagc gattcgtgga
     1981 aaatcaggat cctccatcgt tcgtccttca cgaatgagct gattgggaaa ctcttttgtt
     2041 aaccaatcag gctctttcgt catctctttg atggcccgat aatacttttt ggccatgtca
     2101 atggaactcg tggttaagat tgcagatttc gttggcctgc catttcgaaa atcaaatttt
     2161 gtataggcat tatctggacg gaacatttta tgaatgactt tttggatatg ttcatctgct
     2221 tcaaaaacag ctgggtccaa ataactttct tttttgacag gttccatttg atcaatcata
     2281 cgattgatct gttctgatga atactctgca tatgtttcta cttcttttaa tttccgatag
     2341 attttattct ctagtgaagt cggctccacg gtgttttcat gctctacttg aaatcctaag
     2401 acagagccat cttctagcgc attcttaatg gtataggtat gcaagacctc tccatactga
     2461 tcatgggttg tacgtgccaa ttgccctttg gcttgtttcc gattctcagg aaaaatcggt
     2521 gtacctgtaa agccaaacca agtggatttc ggaaacattt ttttgatttc ttccatattt
     2581 tcagcactta acgctcgatg acactcatct actacaaaca cgatatgttg gcccattaat
     2641 ttttggaagc gattggttcc ttttttctct tcttgtttct ttgcatattt caacgccgca
     2701 tctagttttt gacgggttgt aatgattaca acatttgcat tggcatctgc caacagggtt
     2761 tcacttaatt ctttggcact tcccgttcca acgatcaagc tattcgcttt ggcgttcccg
     2821 gaagaaatcc cagtattaaa ttccgaagca aattttgtaa actctgtggt ggtttgatta
     2881 tctaaatctt tgcggtccac taacatgatc gttcgatcga tccccgattt tcgtgctaaa
     2941 agcttagtag atacaaaact agtcaacgtc tttcctgaac cagtcgcatg ccacacatac
     3001 cctgattgat gtttatttgc ggcaataaac aaggcttgaa tcgcatgtac ttgataagga
     3061 tgtaacacca tgagggtttt attatcttga tcttcactga cgattgtata atccgcaatc
     3121 aaacgatgag catccgggat atttaacact tgtttacaaa actcatataa gttttctact
     3181 ttttcattgt ctttcgttcg ccaactaaat aaaaacttag ggtgcaagtc tttcggtaag
     3241 gcatttgcaa aataccgagt ggtttgttca ttggaaacca caaacaactg taaggtcgaa
     3301 aagatattgt tccgaaacat accttcttct gcatattttt tgatttggtt aaatgcctga
     3361 taaacaccat cttttgcagt tacttgtttc agctcgattt ggacaatcgg taatccattg
     3421 attaataagg tgacgtcaaa acgtcgatcc cgtgcttcta tgttacttcc acgttttgca
     3481 atttgatgga ccacttcata agtagagatt cctccaccaa tgtcttgatt ggaataaagg
     3541 ataagtgaga cagaacccaa ttgcgaatct tcccgttcaa tcgtgatccg agccatccca
     3601 ttttcacctt ttaaccattt cgcagcatca aatggggttt tcgttcgcag cagtaattcc
     3661 gttttgatcg tttcaaattc tttatcggtc aaaggaaaat cattcagttc tgcttgatta
     3721 tttgagataa ttttttggcg taaattgacc caaaggtctt cttctgattt tagatccgga
     3781 cgatacgtcc actgattatg cccttctcca agtacacgaa tcaactgttc ttcgacttct
     3841 gcttcctcac ggtgactaat tttcattctt cttccctcct agacaaacat cttttgtaag
     3901 aagctttttt tcgtttcttt tagtaaatct aacttacgtt gatgaagagc gatcgtatca
     3961 tctagctgtt tgaagaaagt accgattttt tgttgttcat cctttacagg aaccttaaca
     4021 ctgatattct caatatcaga actgttataa gaaggcaatg cccctacttg ggagtatctt
     4081 ggcaaattta tagtttcaaa caatatttta ccaaaataga tatcccaagt attattaaat
     4141 aaataagcca tggtattgtt atctattaag aaagggcttg tgaccaaacg ttttctatta
     4201 agcattattg ctgcgccaac tttagcaaat ataatcgctg gcacatcttt tattggcttc
     4261 cattttttac gctcaatttg ctcattagat acataatgat ttgcatttct catttcatac
     4321 tcattaccaa tgttattcat gtcggaaact ttaaaaaatg gagtaccttc agaaccacct
     4381 tgctcggcat caggaaatcc aattcccgat tgagttttac ctaattctcc caacttacgc
     4441 tcttcccaat cttccgtaaa accaggaaac cggatttctg gcacttttgc tccgttttca
     4501 gggaacattt tttgtaagaa tccttttttc gtttccttca gcaaatctaa cttacgttga
     4561 tgaagagcga tagtgtcgtc gagttttttg aagaatatgc cgattttttg ttgttctttt
     4621 aaatcattgg gaatatagaa tactgtatct gaaacttttt tccagtctga acgaggcatt
     4681 tttgttccag atgtatcatt tgcagccttt tgatatctat cagcttgaat aagagaataa
     4741 ataaagtccg agtcgctctt cttagctcta aaaacccaga aatccccaat cgctacgcct
     4801 gtaaaagttg ccttgagcca attttttaaa tatggacgta actttccata tagaatatca
     4861 tttggtaaaa attcaatccc ttttctatta tcaaatttct ggctcacatc tttattcagt
     4921 ctaccttctc ctgccacgat atcttcaaat tcaacttttg gaagtctact ggagtttgta
     4981 cttttattaa gtctaacaac taaatcaatt aacttacgct cttcccaatc ttccgtaaat
     5041 cctgggaaac ggatttctgg tcgtgtatca ttgctcatgt ttgaacacct ccagcgcacc
     5101 ttgtaaccac atttcgtttt caggtgttgt ttgcagggaa gagatagctt ctaaaagttc
     5161 tttttctagc acttgctgtt cttgtcgtat cttcttgatg tcatttccga catgaaccat
     5221 atcaattggt tcttcttctt cgaaagtatc tacatagcgt gggatattta agttatagtc
     5281 attttctttg atttcatcaa aggttgccaa atgagcgtat ttctcgacat cttttctttc
     5341 agcgtaggtt tcgaggattt tttgaatgtt ttcttccgat agtttatttt gatttttccc
     5401 tttaacaaat tcacgactag catcaatgaa taatacatct cgagtttgac gattcttctt
     5461 caacacaatc accgtcgttg gaatcgatgt cccaaagaac aagttcgcag gcataccgat
     5521 cacagcataa atactgccat cttctagtaa tttttgacgg atgacccctt ctgcagcgcc
     5581 acggaataaa actccgtgtg gtaagacgat ggccatggta cctgtttcct tcaaatgata
     5641 gaacccatga agaagaaacg caaaatctgc tttggatttt ggcgctaatt tcccataacg
     5701 attaaaccga gaatcatcta agaaagtcgt atctgctgac caattagccg aataaggtgg
     5761 gttcattact actgcatcaa atgtgtaagg ttcatctgtt ggccagtcct tattcaacgt
     5821 atccccattg cggagattca tttcttcggc gtcgacacca tgtaaaatca agttcatttt
     5881 tgctagattg tatgtcgttg tatttagttc ttgcccatga tatttaacgt tatctgggtg
     5941 tgttaagtag ttacgtacgt ttaacatcaa tgaacctgaa cccatcgttg gatcaaaaac
     6001 actaaagaat cgtcgttcct tttgatcgag cgttacgatt tgcgccatca tatcagaaac
     6061 catatgaggt gtgtaaaatt ctccggcttt cttccctgct tctgaagcaa attgactgat
     6121 cagaaactca tacgcatccc cgatcacgtc cccatcgtgt tctaaaacat ctacatcatt
     6181 caatttcttg atgacttcgg taatcgtcac atttcgttgt tgctcatctg ttcctagttt
     6241 ttttgattgg agatccacat catcaaataa cccattaaat tgattgtagg tagatgccaa
     6301 ttgcacaaag gctttgttta gatcgttcaa ttggaacgtt gcttgttttg cttgatccgc
     6361 taagacgttg aaaagatact ctggtgcaat tgcatatccc aaaatatcaa cgattgtggc
     6421 aatcagatct tcttttgatt cttcatctga aagtaattca cgatacaaca ttgtttgttt
     6481 gcttactgtg tcatattcct ctaaggattc atctgctaaa agaaccactt gttccaacaa
     6541 tcgatcggat aaatatttat agaaaatcag tcccaataaa taatttttat attctgacgc
     6601 atccatttta ctacggagat tatctgccgc actaaataat ttttgattta attctgcacc
     6661 caaaaagata cactcctatc tcttatttaa agttgctata taccctctta ttttagcata
     6721 ccccctttta taaaaagcaa aaaaaaaaga aagaaactta ttcttgctaa taaactacgc
     6781 gaaaggagtc taacgttgtt tgatataact tagactgatc gttaacttat tttttatatt
     6841 tctacatagt tatctttaga accatttcag atacatatga aacaattaca tatgattttt
     6901 tcataaaaaa acagtactgt ctagtagtat aaaatataca aatttcttaa aaattttttc
     6961 actaaaatca ctacctgaaa cagtctaaaa cacttatata tcaacgttta atgaaa
//
LOCUS       DACDLM010000108         6468 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.110, whole genome shotgun sequence.
ACCESSION   DACDLM010000108 DACDLM010000000
VERSION     DACDLM010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6468
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.110"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(1148..1546)
                     /locus_tag="IV356_002664"
     CDS             complement(1148..1546)
                     /locus_tag="IV356_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016286.1"
                     /translation="MRLRRNKNYTTIILEDFTDQELLIVGKTKADFIEKGNASIVKAS
                     KVAVEKYFDSLEESAKEIFNGEKAGSYELDGIRFSLIPTTENIIPKKLYYIFSSEKYT
                     SMKPCILDWQWLIDAVLDVKCSKYNITLGC"
     gene            1762..2817
                     /locus_tag="IV356_002665"
     CDS             1762..2817
                     /locus_tag="IV356_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParM/StbA family protein"
                     /protein_id="HAP9016287.1"
                     /translation="MKEPLLFSVDLGNKSVKEMSTHVSPLSLPSRILNKNIINSGRFS
                     NIGSSLKRSLNVSEYSLVNTTESYYFGKDIHELGKDDYVIESLGFGISRYKQETYQNI
                     LSFSLANLARLEDQSDDVLTVNLVLGLPSSDYTETIVKYVMQQATRQHSVEVDGKAYN
                     INVDTVWVLPQPIGTLYNLLLADDGSVQDETLISQKIGFVDIGGGTKLFDVVQNFEID
                     ENNREQKDTGIFTLYNRIVNMLDLPISPNAFQLEKIIREGKEKGVYLFKPSGNESFDI
                     SEVVEREIKTYTNMVVAEVLATFKNFTTLDKVVFTGGGASIIDKQLVKDKIPHTLFVE
                     DSEFSNVKGFYKFGLTQ"
     gene            2837..3181
                     /locus_tag="IV356_002666"
     CDS             2837..3181
                     /locus_tag="IV356_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016288.1"
                     /translation="MNKGKSERYVVIINREKVSELPLAEFLESEYETLGVKYSQTIKK
                     ALNLYRRVKNNEVTIIEAGNDSKVAEVKNKPTDHNPIQQEHPSTVTSGHSAKKKKPML
                     KGFNAPSNKDLL"
     gene            complement(3362..3658)
                     /locus_tag="IV356_002667"
     CDS             complement(3362..3658)
                     /locus_tag="IV356_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016289.1"
                     /translation="MIEVKENRFKKFAEAEVEEVPEVVEAVEEPKQTPKETRSSLVDK
                     LKSDSSEKKKNYQFTLQPSQRKKLSKISEKLGIRSDSALLGEMIDNLYDEVFGE"
     gene            complement(3662..4480)
                     /locus_tag="IV356_002668"
     CDS             complement(3662..4480)
                     /locus_tag="IV356_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP9016290.1"
                     /translation="MEKKLSIITGNIEKGGTGKTTTIYNLGGYAVENLGMKVLYIDED
                     KSQNLSKRFPDAFSKAKRENTINHLYLHGSAEPLAINENMDILVAGEDLKQVEMQMRD
                     MPNNRTLLFRWIVVNYEQLKEKYDLILIDTHNDAGLLAQNAWAVSDLVVGISDPSKDG
                     FEALLKLGKDIDALAKQLIDIKTGETLMETKYATIGSRIKHNTNSSREFLELVPTLSN
                     YLGYVQEKELLNATSLEGKNIAEFAKDKNIYRKNKDFFESTFTLYNKIIDTAQE"
     gene            4700..4921
                     /locus_tag="IV356_002669"
     CDS             4700..4921
                     /locus_tag="IV356_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HAP9016291.1"
                     /translation="MPVISIRVSKEEKDFLEKVAEFNGDNISEFMRSNSLQTAETLVD
                     FATYKELMKEHEENDQSISHEDMLKELGL"
     gene            4923..5189
                     /locus_tag="IV356_002670"
     CDS             4923..5189
                     /locus_tag="IV356_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAP9016292.1"
                     /translation="MSYQVRYEREAQKALKKMDKFQAKVILNWIEKNLVGTDDPRKHG
                     KGLTANKSGYWRYRVGAYRIIADISEHEVTILILSIGHRSEVYK"
     gene            5302..5841
                     /locus_tag="IV356_002671"
     CDS             5302..5841
                     /locus_tag="IV356_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016293.1"
                     /translation="MYNKSVNKLINLQKERFFMGWYGAYSSANEVIEEKKGYAKNGLE
                     IVDTKVTKTYGIILFKDAEGTYDIDSFIFRDEMYKPIYFLNDSPAYFKKIPKKWLKFF
                     VGDQEKMVKRQLDRIKEESNKPKLDDLLVAGKTYSIWDGSYVAVYQYKLKRSFIFRLQ
                     DGSLTRFTRLSAGDVKEVA"
BASE COUNT         2260 a         1080 c          969 g         2159 t
ORIGIN      
        1 tgtttcgtgt taagtttctt tatattacta cgcgccttgc gtataaaact tctttattca
       61 tcccacgatc catgttattt tatatttcct ttttcatgtt atttttagcc agaaaccgat
      121 caagttttta cctattccca aaatccattt attcgttatt tttttctgat taagaataat
      181 tatttgatgc ttaaattagc taaaaaagcg atttgttact gatataatca tgatattaaa
      241 gctgaattag gcagaaagat aaaatgttcg caaaatcaaa gtatcaatta tcttgttttt
      301 ttataaattt gtaagtaaaa atctaaaaag ttttctttta attggtatat gtattaaaat
      361 cacattcaat cactcataaa agtatgcgat ttcatttttt tggatgagat taatatcaat
      421 aaataacgat gtaaaaacca tttattatgc tcttttataa gggtattaat tgatctaatt
      481 tgaaaaaata attcacaatt taaatgtttt aatattacga ataaaataat gttatcgtaa
      541 aatggtataa aaaagctaaa tattatattt ttgttatttt attagcagaa aaatttaaat
      601 agttttacaa gaatccgtag aaatatattg gttttgcctt caaattaata ctggatcata
      661 ttaatctgaa tataatatat gaactaataa atagcttaac ctagctattt tgttttttct
      721 gatcactatt tatacagcat tagtaaataa aattttaaaa ataaaaaaaa taaggcaaaa
      781 aaagtatcaa cataaacata tacatataca cgtttatgtt gatacactta atttgtcctt
      841 taaaaagcac ttttttgata ttatgttatt ttataatctt attacaagct gattgttagg
      901 cgttgccctt tcattacatt tattaacggt tattttatcg tttaatttat taattatttt
      961 tgatctaaaa cttagcttaa caaataaata attaaccaac cgccagataa aaatgcgatc
     1021 attgctaata cataagcaaa gataaaaata tgttcgatca gcttaaaccc tgatgcgatt
     1081 aagcagacca agtaaaatag aaattctctt acagataatg gtaattttct aactagcata
     1141 ctcataatta acaccccaaa gtaatattgt attttgaaca ttttacatcc aatacagcat
     1201 caatcaacca ttgccaatcc aaaatacaag gcttcattga agtatatttt tcagatgaaa
     1261 agatataata taatttcttc ggaataatat tttcagttgt tgggatcaag ctaaatctaa
     1321 taccgtctaa ctcatagcta ccagctttct ctccattaaa aatttcctta gcactttctt
     1381 ctaaagaatc aaaatatttt tcgacagcaa cctttgaagc ttttactatt gaagcatttc
     1441 ccttttcgat aaaatctgct tttgttttac cgacaataag taattcttga tcagtaaaat
     1501 cttctaaaat aatggtagtg taattcttat ttcttctcaa tcgcatcagg atcactcctt
     1561 aatataattt atgtttttat aatatcataa taagataaat ttgcaagcat ttatttacac
     1621 ctttttattt acactttatt ataattaatt atacttttat gattgcattt ttttcttata
     1681 aacagttgca actaatagta aataggtgta aactattttc gtaccgaaat accataaaca
     1741 caaacagaaa gaggtcatac catgaaagaa ccattattgt tttccgttga cttagggaat
     1801 aaatcagtaa aagaaatgag tacacacgtt tctccactct cacttccctc tcgtattttg
     1861 aacaaaaata tcattaattc aggacgtttt tctaatatag gttcctcatt aaaacgatca
     1921 ctaaacgttt ctgaatatag cctagtaaac actactgaaa gctattactt tgggaaggat
     1981 atacacgagc taggaaaaga tgactacgtg atagaatcac taggttttgg gatcagcaga
     2041 tacaagcagg aaacctacca aaatatccta tctttctctt tagctaacct agcacgttta
     2101 gaagatcaat ctgatgacgt tttaaccgtt aatctagttt taggtctgcc ttcatccgac
     2161 tataccgaaa caatcgtcaa atacgtgatg caacaagcca cacgacaaca ttcagttgaa
     2221 gttgacggta aggcttataa tataaacgta gataccgttt gggtactgcc acagccgatt
     2281 ggaacactat ataacctcct acttgctgat gatggtagtg tacaagatga aacattgatc
     2341 agtcagaaga tcggttttgt tgatattggc ggtggcacga aactttttga tgttgtccaa
     2401 aattttgaaa ttgacgaaaa caatcgtgaa caaaaggata ccggcatttt tactttatat
     2461 aatcgtatcg taaatatgct tgaccttccg atcagtccta atgctttcca acttgaaaag
     2521 attatccgag aaggcaaaga aaaaggcgta tatctattta agccaagcgg aaatgaaagt
     2581 tttgatattt cagaagtagt tgaaagagaa ataaaaacat acaccaatat ggttgttgca
     2641 gaagttttag ctacattcaa aaacttcaca accttagata aagttgtctt tactggtggt
     2701 ggagcttcta ttatcgacaa acaacttgta aaagataaaa ttccgcatac cttgtttgtt
     2761 gaagacagtg aattttctaa tgtaaaaggc ttttacaagt ttggtttaac tcaataaaac
     2821 agcgaaggag atcaacatga ataagggaaa atcagagcgt tatgtagtta taatcaatag
     2881 agaaaaggtt agcgagttac ctttagcaga gtttcttgaa tccgaatatg aaacactagg
     2941 cgttaaatac tctcagacga tcaaaaaagc tttgaaccta tatcggcgtg taaagaacaa
     3001 tgaagttaca attattgaag caggaaacga tagcaaagta gcagaagtaa agaataaacc
     3061 aactgatcat aaccctattc aacaagagca tccttcaacg gttacatccg gtcattcagc
     3121 aaagaaaaaa aagccaatgc taaaagggtt caatgcacca agtaacaaag acttacttta
     3181 aaaataaaaa ggcgaggtta caatacctag cctttttatt atgtacaaat ataaacataa
     3241 acatatacgt atacatgtat ataaacatgt atacgtatat aaccataaac acgtatatga
     3301 aatttagtta agctatacct aaccgcttat tccaataaaa aaatgatcag ctttaaactg
     3361 atcactcacc aaaaacttca tcatacaagt tatctatcat ttcgccaagt aaagctgaat
     3421 ctgatcgaat tcctaacttt tcgctgattt tagatagttt ctttctttgc gatggttgaa
     3481 gcgtgaattg ataatttttc ttcttttcag aactatcact ttttagttta tctaccaaag
     3541 aacttcttgt ttctttaggt gtttgtttag gttcttcaac tgcttcaacc acttcaggaa
     3601 cttcttctac ttcagcttca gcgaattttt taaatctatt ttctttcact tcaatcactc
     3661 cttattcttg tgccgtatca attattttgt tgtatagcgt aaacgtgctt tcaaagaaat
     3721 ccttattctt acgatagata ttcttatcct tagcgaactc agcaatattc ttaccttcta
     3781 agctagttgc attaagcaat tccttctctt gtacatatcc aagataatta gataacgttg
     3841 gtaccaattc taggaactca cgacttgaat tagtattatg tttgatcctg ctaccgatcg
     3901 tagcgtattt agtttccatc agtgtttcac cagtcttaat atcaatcaac tgttttgcta
     3961 gtgcatcaat atctttacca agcttcagca aagcttcaaa accatcttta gatggatcag
     4021 aaatgcctac gacaagatca gatacagccc aagcattttg agctagtaga cctgcatcat
     4081 tatgagtatc aatcagaatt agatcatact tctctttaag ctgttcatag ttaacaacga
     4141 tccatctaaa cagtagagtt ctgttgttag gcatatcacg catttgcatc tcaacttgtt
     4201 ttaaatcttc acctgctact aaaatatcca tattctcatt tatagctaaa ggttcagctg
     4261 atccatgaag atataaatga ttgattgtat tctctctttt cgctttactg aaagcatcag
     4321 gaaagcgttt tgataggttt tgcgacttat cttcatcaat atacagcacc ttcataccta
     4381 aattttcgac agcatatcca cctagattgt agattgttgt tgttttacct gttccacctt
     4441 tttcaatgtt tccagtaatg attgacaact tcttttccat gattaaacct cccttattaa
     4501 ccttttgtaa ctccattata cactataaac acgtttatgt atatgtttat atacataaac
     4561 gtgtttatat ttatatttgc ttttatattc tacaacataa acatgtatat gtatatgttt
     4621 atgtgtatgt tcatatatat aactattgca tttgtcatac aatcgtagta caatgtaatt
     4681 gaaaaggagt tgataaacta tgccagtaat aagtattcgt gtatctaaag aagaaaaaga
     4741 ttttcttgaa aaagttgctg aattcaacgg agataacatt tctgaattta tgcgtagtaa
     4801 ttccctgcaa acagcagaaa cgttagtaga ttttgccacc tacaaggaac taatgaaaga
     4861 gcatgaggaa aacgatcaaa gtatttccca cgaagatatg ctaaaagagt taggcttata
     4921 agatgagtta ccaagtaaga tatgaacgtg aagctcaaaa agcgctaaaa aaaatggata
     4981 agtttcaggc aaaggttatc ctaaactgga tcgagaaaaa tcttgtaggc actgatgatc
     5041 caagaaagca tggtaaaggt ctaacagcta ataaatcagg ctactggcga tatagggtag
     5101 gtgcataccg tataatagct gatattagcg agcatgaagt gacaattctt atattgtcta
     5161 ttggtcacag aagtgaagtt tataagtaac agacaagctg ataaggcttg tctgtttttt
     5221 tgttaaccca acaaaatcac tgtttacgat cccactttac ctaaaaaaga acaatatcct
     5281 cttgttatta tacacattgg tgtgtataat aaaagtgtaa acaagctaat taacttacaa
     5341 aaggagcgat tttttatggg atggtatggt gcttattcat cagcaaatga agtgatcgaa
     5401 gaaaagaaag ggtacgccaa aaatggtttg gaaatcgtag ataccaaagt aacaaagacc
     5461 tatggaatta tccttttcaa agatgcagaa ggaacctacg atattgacag cttcatcttt
     5521 cgagatgaaa tgtacaaacc aatctacttc ttaaatgaca gtcctgctta ctttaagaaa
     5581 attccgaaaa aatggttgaa attctttgtc ggtgatcaag aaaaaatggt taagcgacaa
     5641 ctagatagaa ttaaagaaga aagcaataaa ccaaaacttg atgacttatt agttgcaggt
     5701 aaaacttact caatctggga tggatcgtat gtcgctgttt atcagtataa actcaaacgt
     5761 agctttattt ttcgactaca agatggatca ctcactcggt tcactcgact atcagcagga
     5821 gatgttaagg aagtagccta aaacttaaat acataaacat aaacgtgtat acgtttatgt
     5881 ttatgtatat gtatatgaat ataaacgtat taggtacgaa cgcttttaaa tgcttttctg
     5941 ggctttgatt ttagggtaga gctaaaacat caccatatga tccaaaacag ctcagaaacg
     6001 catttaaacg tatctgatac caatattata gaaggagtgt atcgtatgat taacctattt
     6061 cttttggtga cagctagtac attattcttt actggaatat cacttataat ttcctatttg
     6121 atctataaga aagccgaaac ttacacaagc aaagcaaccg gactagccgt ttcatccttt
     6181 ttaactttgc tgactttttt tgttactcta tcgttttctt ttgtttagca cagctgatcc
     6241 atcagcaaaa aacctctctt tacattatac acactagtgt gtataatgta attgtaaaca
     6301 agctaattaa cttttaggaa ggagtgacaa tatgctaaca gctacattac agcaacctac
     6361 tcacgttgct attgcagaaa gctatacaat taatgcaggg atcgttaaac agctgatcaa
     6421 ggatcgagaa ttcaaaaagt ttaacagtcg tcaagcgtat aacagaca
//
LOCUS       DACDLM010000109         6467 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.111, whole genome shotgun sequence.
ACCESSION   DACDLM010000109 DACDLM010000000
VERSION     DACDLM010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6467
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.111"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(110..565)
                     /locus_tag="IV356_002672"
     CDS             complement(110..565)
                     /locus_tag="IV356_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016294.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(719..1927)
                     /locus_tag="IV356_002673"
     CDS             complement(719..1927)
                     /locus_tag="IV356_002673"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HAP9016295.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(2039..2371)
                     /locus_tag="IV356_002674"
     CDS             complement(2039..2371)
                     /locus_tag="IV356_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAP9016296.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            2519..3394
                     /locus_tag="IV356_002675"
     CDS             2519..3394
                     /locus_tag="IV356_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP9016297.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(3476..4057)
                     /locus_tag="IV356_002676"
     CDS             complement(3476..4057)
                     /locus_tag="IV356_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IDEAL domain-containing protein"
                     /protein_id="HAP9016298.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(4063..5322)
                     /locus_tag="IV356_002677"
     CDS             complement(4063..5322)
                     /locus_tag="IV356_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAP9016299.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(5324..6370)
                     /locus_tag="IV356_002678"
     CDS             complement(5324..6370)
                     /locus_tag="IV356_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016300.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
BASE COUNT         1804 a         1337 c         1102 g         2224 t
ORIGIN      
        1 aaaatcttgt cacagtccct tattctgaat aaacggtgtg gaagagacag cctatcagta
       61 gtaataagac acatctcttt cacagcctca tttttgcgta aaaatcgatt tattcgaaaa
      121 attccccgta tacatcttct acacgttgat ctggattgat cacgatatac aagttacctg
      181 ttttttcgct gatttttgtt gattgatatt gattgtctaa tccttctgtt cctttatcta
      241 gatatgggaa gtacacaaga tcaggtgtgc catttcggta aaggatttcc attcgctcga
      301 tatcttcgta tttcaatgcg cgattaaaca tgcccatttc cagtccgcct aggttgatat
      361 catgtgtcgc aactgcgtcc ccttcatgga agatttcgat tttaaatcca gcacacggat
      421 ggatttcaac aaattcactg ccattgattc gtccaaaact tgttgtgatt tgtttgatcc
      481 aaagatcgcc gatatgacgg cggttgatcg tccaggtttc tccatttcta aaataaaatt
      541 ttagcgctgt catttcttta ctcattaaaa agactccttt atgatgtaat ttattcttgt
      601 actacctcag tttagcacaa atttatgtaa gtggtcacat cttatgtttt ttcttctaat
      661 gacgtatctg cccactttaa gtagccaaca aagctgagca gatacagtct agtgtttttt
      721 aaatcaattt ttctttcgat aaaaaatcca aaacctgttt tttatcattt tttattcttt
      781 gttctacgac ggctttttca gctaattgca aagcttcact aacccactta ccaggttttt
      841 ttccagtttc ttctagcaag attttaccat ctactgctaa ttcgcttaat gacttgatag
      901 gtaaacgatc ataggattct cctacggcat ccatctgagg tgtttcgtca aaatagatca
      961 tcaattcttc tacttgcagt gcatgttttt tgcctaagaa gtacaattcg aatggttcca
     1021 aagctccagt ttctcgttgt cgtagtcctt ggacaagtgc ttgaacgtct ttaatcattt
     1081 ggttagaaca cttccacgat ttcaaaaagg aacgaatctc attttctttt agatccagtt
     1141 ggctgatcaa taatgcccat gcttggctct cttctttcaa tgggacggat ggtaattcag
     1201 caaaacgtaa aagtgcttcg ccttcttctt tcaaaccggg acagcaaatg tagcactctg
     1261 tttcaataaa tgcatggatt cccgcggccc gttcatttcc caagagcatc ttgatgaatt
     1321 ccacatttat acgttctaca gatattttac ctaatagctc gtggttttct ttgatggcgt
     1381 agaaggtttc ttcctctaat ttgaacccta gttgactgac aaaacgcaac ccgcgcatca
     1441 ttcgtaaggc atcttcatgg aaccgctcat gaggattgcc tacagctcgc aagatctgtt
     1501 cttctagatc ttgcagacca tcgaacaaat cgatgatttc tccatcttct ttcaaagcaa
     1561 acgcattgat cgtaaaatct cttcttttca aatcttctgc caacgaacga acgaattcga
     1621 catgatctgg tctacggtag tcctgataag ttgattccgt ccgaaatgtg gtgatctcat
     1681 attgttcatc attttctaat accaacacag ttccatgttc gatcccaata tctatcgttt
     1741 ttggaaaaag ctgtttgatt tcttctggaa atgcgcttgt tgcgatatcc acatcatgga
     1801 ttggctggtt cagcaagata tcacgaacac ttccacctac aaaataagct tcatatcctg
     1861 cattctctaa ttttttcaga actggaattg ccttttggta ttccagaggt aattgtttta
     1921 atttcatttt tccaaccttt cctgcgtgtt tcttgtcctg agataaagac tcagttgcat
     1981 ggtgactgtt tgacaagtcc gtttcagagt cttcaaggcc aggaccactt catcttgttt
     2041 actcgtcctt acgctcaaag cgattatggt ctctttgatt gaatttttcc atgttttttt
     2101 caaaaacttc agttaagtcg atattcaatg aattagccat gatcatcgta acgaataaaa
     2161 catcaccaag ttcttctgct accgagttaa ctggttcaga agcctttttg cttttttctc
     2221 cataagtgtg gttgacttct cttgccaatt cacctacttc ttcagttaat cgagccatct
     2281 gagctaatgg agagaaatac cccaccttga attgctggat atattcatcc acttcctgct
     2341 gcatactgta taaagaacgc tttttatcca tctttttccc tccaaaacta tcttaccaaa
     2401 actttaacgc aaatcctaga taagagcaat tgagaaaatc gaatttccat gctacattta
     2461 ggaaggaatt tctaaatgga aattctgtga aaatacataa ttgaaagctg gaattcatat
     2521 ggtcaaacga aaaacagtaa aagaagttct ttttatcatt ataggaacaa gtatttatgc
     2581 atttggtctt gtttacttga acatcgctaa tcatttagca gaagggggag tctcagggat
     2641 caccttgatc ttaagagctt tatttggtat tgatccagct tatacgactt tattaatcaa
     2701 catcccattg attttactag gaggaaagat cctcggtaaa cgttccttgg cctatactgt
     2761 tctaggtaca ctttctttgt cattcttttt atggatctgg caaagggttc cactagaaat
     2821 caatttacag catgatctac tgatcgtttc tctacttgcg ggtttagttg caggtgtagg
     2881 aagcgggatc gtctaccgca tgggtggaac aacaggcggc agtgatatta tcgctcggat
     2941 tttagaacaa aattacggca tcactatggg gcgttcccta ttggcatttg atatcatcgt
     3001 cttacttgct tcattaacct atatcgactt gaaacgtatg atgtatacgt tgattgtttc
     3061 gtatgttttc agtcgtgtga ttgattcgat cttagatggc ggatattctg caaaaggtct
     3121 acttgtcgtc tccaacaaaa gcgaagagat tgcaccacta ctgatgaccg gtctgcaaag
     3181 aggtgtgact ttcctttctg gagaaggcgc attctctggt aattcaaaaa aaatcatcta
     3241 tatggtcgtt agctctagtg aattaactga agctaagagg atcgtccacg agattgacga
     3301 aaaagctttc ctttcaatca tcaatgtgca tgaagtggaa gggcaaggct ttacttattt
     3361 gaagccacag acaagattac tgaaaaaact ataagaaaaa agacaaagat aggctatgag
     3421 gaaagattcc acatccagct gacctttgtc ttttttagta ctatactatt tttaactaat
     3481 tgttatgttc acttacccgg ttacttttct tttgtgtctg caaaaggatc tttcggttaa
     3541 cttcatcaga taatttcaaa aaagcatccc tatctccatc ttctagtgct tgatcgattt
     3601 gagcataaag catttttagt tttgcctctt cttctttttc ttgaaaatat cgttcaatta
     3661 attcagtatc ttcttcactg actgaagaat cccaagaaga aaatggattg tcttctaaga
     3721 tagatagata ttctcttgtc tgccaagcat tttcgaatat acattccaca tataaaggct
     3781 ttttccaatt caaacggatt tcatgaaaaa tctggtctgt gtccgtaaat tcttttccct
     3841 gcaaaaacaa tttcatgggt tccccttcaa cagatagatc actgatctgc agtcctcgat
     3901 ccgcaaaatt cgccccttca acaaagtgga cattgcttaa aatcgcttca tgattggcaa
     3961 gataattcaa gatccaaaaa acttctcttc ggctaaaaga tacatgattg accatccacg
     4021 ttaaaaaatt cttcttttcc cgtacatcaa ttagcatttt tctcacctct ctgttaggtc
     4081 atctaataat gacagtgcct ccatatctcc tggttcaagt gttaaataat aagtcaataa
     4141 ttcttgcgct cttttcagct gcccttcttc tcttaagaaa aaggcatact ctttcaagaa
     4201 atctggttca tgtgatagtt catgataagc ctgttcatag tgtacagctg caacggtaaa
     4261 gtcttctaat tcattataag catgggctag gttccattct gcataaggat tagcagtttc
     4321 ttccatctga ttgatcactt gtatcacatc ttcatatctt tcatcatcca agtaaagatt
     4381 acttaaagta agtaatgttt catcttgttt gtctcctact tctaaagctt tcagtaaaag
     4441 ttcttctgct cgctgtctat catgcagacg gaaagcattt tccgaggcca ggtgataaag
     4501 ttcgacttgg taaggatttt ctttgattcc ttcttctaac actgtttgtg cttcttcaat
     4561 catttcttct tcttgaagag cttgtcctag atatagatat aacgattgat aatgcggatt
     4621 aacttctcga agttcttcca gatagttgat tgcctgctga ttttctttca attgaagatt
     4681 cgtaaaagct agctggaaca gtcgatcatc tgtcctttct tctttcagtg cttcttctaa
     4741 aggtacgata gctgcttcga attctccttg catacttaag gattgtccta aacgttcctg
     4801 catcgagatt cctgaaattt catttatccc gcttgccaac aatgtttcat aaaccactgc
     4861 tgcctctttg aaacgatcaa ctgaaaaata caattcagct agcgcaaact ggatcaatgg
     4921 ttcatcagga agcaacccag ctgcttcttt caattttgct tcactcactt cagggattcc
     4981 gataacttgg tacaaatcag ctatcgccaa taagctttgc ggatagtaat cactttgctt
     5041 atccactttt tccaggtatt caaaagctaa gtcgatctca ttatcttcga ttgcaatttc
     5101 tgctaacggg atgttcagtc cgtcattttc tgggtattgg ttgatcagtt gttcaaaaat
     5161 ctgttttgct tcgatcaaaa agccaatagc cagcaattct tcgcctagtt cagctaatat
     5221 atctgctggg tcttctttta atgctttttc taaaaagatt tgtgcttgtg acaagtcttc
     5281 atctgataaa gcttgcaaca ttttttcgct atttgtattc atttcaattc cctcttatct
     5341 cactgacgat ttgttgaaat accgtcattg ttctcaataa ttctttttcg tttggatgtt
     5401 ggtatccgtc tattatacct attttttcta aaacaagtat ttttttgctt ttttctgcca
     5461 aaaaaagaac tttttccaaa tactccatct ttgaaatctg ttccagccag tggattggat
     5521 agccaagcaa gtccagccac acaaaaaagt tttttagttg gaaatcaaaa ggatatgctt
     5581 ggagattcca cacgaaatga aacatcattc ctaaaaattt tttcatacta gcagaaagta
     5641 gatggccatt ttcggtcaga taaaaagctt gttcaaacag tttaccataa tttgacaggt
     5701 tttctgcctc taattgataa aaatagatca tttcttcgat catcccggca aacggccgag
     5761 tcgttaattg ctttttattt ggatagtttt tatacagatt ttgcaaaaaa cgatgatcac
     5821 aaatcattcc gcaacagata aaagtcaaaa agtcaatctg ctttccgtcc acctgccgct
     5881 cgctgattgt ttgatcataa acgatgcgtt ctggcagatt gatggtttgc agcactacac
     5941 gatttggtag ctgcaaaatc gtccgctgcg gtgttaatgc tcggcttaga gaacggatcg
     6001 atacagggat catccatagt gatgaatcaa gggttgtatg tttttgaaaa aaacctgcca
     6061 gatccatgat cccttcattt ccaaatccga tgataaacat ggattgattt tcgggatagc
     6121 gtttgacgaa atcaagcagg ttctttaatt ctgttaaatg attgcattga gtgttggcac
     6181 aaatatacca gtcattgttt gcttgatttg caaataacgg gttgatctta tctgcaaaca
     6241 aatcataata gcgctgattc gttaaaaata agattggctg atcaatggaa agttctctta
     6301 gctgactgac tagcgtttct ccgtaaaaca ctttcgtcaa cgcatcttct acttgataat
     6361 caagttccat acgcatccct cctcttctta tttttatttt accattagta agcaaattct
     6421 agaaaagata agagcaaagc tcacctcata acttggaaat aaataaa
//
LOCUS       DACDLM010000110         6432 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.112, whole genome shotgun sequence.
ACCESSION   DACDLM010000110 DACDLM010000000
VERSION     DACDLM010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.112"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(99..1229)
                     /locus_tag="IV356_002679"
     CDS             complement(99..1229)
                     /locus_tag="IV356_002679"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HAP9016301.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     gene            complement(1878..3080)
                     /locus_tag="IV356_002680"
     CDS             complement(1878..3080)
                     /locus_tag="IV356_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP9016302.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="IV356_002681"
     CDS             complement(3140..3343)
                     /locus_tag="IV356_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAP9016303.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="IV356_002682"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="IV356_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            4880..5692
                     /locus_tag="IV356_002683"
     CDS             4880..5692
                     /locus_tag="IV356_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP9016304.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
BASE COUNT         1930 a         1313 c         1008 g         2181 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcataga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatattttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt ca
//
LOCUS       DACDLM010000111         6303 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.113, whole genome shotgun sequence.
ACCESSION   DACDLM010000111 DACDLM010000000
VERSION     DACDLM010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6303
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.113"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            334..714
                     /locus_tag="IV356_002684"
     CDS             334..714
                     /locus_tag="IV356_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HAP9016305.1"
                     /translation="MSEQHQNLASDHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVAPD
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            696..1610
                     /locus_tag="IV356_002685"
     CDS             696..1610
                     /locus_tag="IV356_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAP9016306.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     TLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPNHQIAIYTHTDKDHIHN
                     HIVINSVNLETGKKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKTEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYTQFCDSLKTFGIHCLNRGKNFTYELVHKKK
                     KVRSNKLGKDYEKETILHELDRRERTYNQQRTNELRRARASIRETAEEVRREQRTFTP
                     EQSEIRPTRRNHEQHVERGTDHQQELSL"
     gene            1855..2544
                     /locus_tag="IV356_002686"
     CDS             1855..2544
                     /locus_tag="IV356_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016307.1"
                     /translation="MAFYLPYLLISASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLV
                     GVIFALSIVLSGLFGVLEGNKRVSRSILLGDITQKYEAACDKKKKEQALAQKMEEFTA
                     CYEDMNNIFVDQEKRLTDKNMKKLTRFYQNLPEKQQKEVQEKYEQVKKDVQYFKDTQT
                     EEACCNLFSDTIPFSTSEQERKERQQSVTYERYETLLQQATNIQNPTKKETALNYLES
                     VKEWLDQQQQN"
     gene            complement(2665..2751)
                     /locus_tag="IV356_002687"
     CDS             complement(2665..2751)
                     /locus_tag="IV356_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011302749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HAP9016308.1"
                     /translation="MFERFICPLLVEVCVSLFSYWLNNRNKK"
     gene            3427..4377
                     /locus_tag="IV356_002688"
     CDS             3427..4377
                     /locus_tag="IV356_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HAP9016309.1"
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVR
                     LTFDQLKDLSNYKATANNRFINDLEMTYDKLMDLRFGKRSANGLDIDRFVMFSEFKIR
                     GTAKDPYVDIQVYEKALPLLNNLDEWVRYSLQQFNELQSSYAKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYWNNQANVDNRVIKPIRQELTAIFKGLSIKKKYGKGRGKPVV
                     GYQFTFKPEIKKADDFNKHAPTKEEQNKALALADKQKEYEEPATTINEKIKQKKRELE
                     LLQQIKQLEKEKEALEKQTESALSKKEKKSLLSDLDNLFQ"
     gene            4398..4931
                     /locus_tag="IV356_002689"
     CDS             4398..4931
                     /locus_tag="IV356_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAP9016310.1"
                     /translation="MQPQETFTIKELSELFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLGNQMLLDRLHEYEQDNDKNVNIPSKNVVTNKLLDQLREENEFLRE
                     QLALREQNNSHIQKLLDQQQQLTLQANKQIEKLQEKLQLTYTEEAPENDSTTLSEATE
                     TIDKQIDTEKKWWQLWK"
     gene            5567..6100
                     /locus_tag="IV356_002690"
     CDS             5567..6100
                     /locus_tag="IV356_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016311.1"
                     /translation="MKKFTLGVALLTIGAVVLPSTTIVYASENSQVVSLNENNATENV
                     VIEYTEDGMVVTKYEDGYSAEDFANSSDIMTRAAVARWGKKEYTNIAVTTGVAANAIN
                     AAFWAGGKASTSMFGIPGWAIGALLTGASWTKKGASPGNAVAKEWDKNGNGWIGFYYQ
                     RGYDAAGRVVATRYSTL"
BASE COUNT         2323 a         1103 c         1174 g         1703 t
ORIGIN      
        1 aaaaaaaaat aaatcgatac attttagaag aatagggttg tttgaatatt acaaagcaac
       61 aatttcacct tcggtgaaat aagcgaaact ttacaaaaag tggctagcaa atgctagcct
      121 ttttttgtat tgtggagcgt ggattttgag ggggattcaa gggggagctt gcgctccttt
      181 gacaagcggt tatttgcacc aaatacggag gtatttggct agcaaatata gagcttgcca
      241 aaccctttta gtgagcttta ctcattgtac ctttttaggt acaatggtat tgcgaacgat
      301 acgtccgtag gacgtactga aagggtggga cttatgagcg aacaacatca aaatttggct
      361 agcgatcatt ctaaaaaata tacctatcga tccgagccaa aacaaatcag ttttcgagtg
      421 agcgaatccg aatttgcaaa gctgaagcag tcagctgaag ctttgcaaat gagtgtgccg
      481 gctttcgtga aagccaaggc acaaaacgcg cgtctggtga caccgaaagt ggcgccagac
      541 attgcccagg caatcgcgcg cgatttagcc aaagctggag ggaatatcaa tcaaattgcc
      601 aagtggtgca atacacacca acacgacgtt gctcctgatg atgctcaacg tttatccgaa
      661 aacctaaaaa tcatgcaaaa ggagctacaa aagatatggc aacagttaaa gtaagtcgaa
      721 ccacttcatg tagccgagca atcaattacg cagaaccacg agcaaccgtc aaaacaggaa
      781 taaactgtga cattgattat gccaaaagtg aaatgaaaca aatacgcacg ctttatggaa
      841 aagacgatcg tgtacaagca cacttattga ttcagtcctt tcgaccagga gaaattaccg
      901 ctgaaaaagc caatcaacta ggggcagagt atgcgaaaaa aatagcccct aaccaccaaa
      961 tcgcgattta cacacataca gacaaagacc atattcataa tcacattgtc attaactccg
     1021 tcaatcttga aactgggaaa aaatttcaag cccatgggca agcattttta aacaaatgtt
     1081 atgacctaaa tgacgagatt tgtcttgaac atgacttaac aatcacggaa cgaggaaaga
     1141 aaaccgaaaa acgaaccatg tctgaaatta aattaaaaga aaaaaatgaa ccggtttgga
     1201 aagacgaaat tcggtttgcg attgatcaaa caatgaaaaa caaaaaaact cgaacgtata
     1261 cccaattttg tgattcactt aaaacattcg gcattcattg cttgaatcgc ggaaaaaatt
     1321 ttacttacga attggtccac aaaaagaaaa aagtacgatc caacaaacta ggaaaggatt
     1381 acgaaaagga gacgatttta catgagctgg acagacgaga acgaacctac aatcaacaac
     1441 gaaccaacga gctacgaaga gctcgagcta gcattcgcga aactgcagaa gaagtacgaa
     1501 gagaacaacg aacttttacg cctgaacaat cggaaattag accgactcga agaaaccatg
     1561 aacaacacgt tgaacgagga acagaccacc aacaagaatt atcgctctaa aacgttaaaa
     1621 gacatcgaaa acgaaataaa gagacaacgt gcctttcttg cgccttatac ccaagaaagg
     1681 atacaaacta cgatggattc acaagtcaaa aaactccacc aagcgctatt agaccagcga
     1741 aaccaagaac aaaaaaaggc tttaattcaa cgatcgatgg atattcttgc ccccttatgt
     1801 tgcttagtac taacattatt agccttttgg ttggtatggg gagaataaac agacatggca
     1861 ttctatttac cctatctact catttctgcc agtattttag gaattatttg gcttagctat
     1921 aaggcttatc aaacaagata ttcattaaaa ggctctaaaa ttcgatttaa gcgattttta
     1981 ttggtcgggg ttatatttgc cttatcaatc gttttaagtg gtttattcgg cgttttagag
     2041 ggtaataaac gtgtttcaag aagcatttta ttaggggata tcactcaaaa gtatgaagca
     2101 gcatgtgata aaaagaaaaa agagcaagca ttagcacaaa aaatggagga atttaccgct
     2161 tgttatgagg acatgaacaa tatttttgtg gatcaagaga aacgtttaac agataaaaac
     2221 atgaaaaaac tcactcgttt ttatcaaaac ttaccagaaa aacagcaaaa agaggtacaa
     2281 gaaaaatatg agcaagtaaa aaaagacgtg caatatttta aagatacgca gacagaagaa
     2341 gcttgttgta acttatttag cgatacaatc cctttttcaa ccagtgaaca agaacgaaaa
     2401 gaacggcaac aatcggtcac atacgaacgt tatgaaacac tgcttcagca agcaacaaac
     2461 atacaaaatc caacgaaaaa agaaacggca ttaaattatc tagaaagtgt caaggaatgg
     2521 ttggatcagc aacaacaaaa ttgaatttga ttagcaatca tgttaaactg aacctgcaaa
     2581 tgatcaaaca ttagatacac gaaagcccca gagaggtcgg attctctggg gctttttttc
     2641 aggttgatgt cgcctttatt gattttactt cttgtttcgg ttattcaacc aataactgaa
     2701 taaagagaca caaacttcta caagaagggg gcaaatgaac cgttcaaaca ttagatacac
     2761 ctccttccag tcgcaagact gtcggatagg cgacaagtta ttatacctta caaaataaaa
     2821 tctgtgtggt gtttttaagt atcccttatt ttcgggttgt tagggcttgc cctgaccgcc
     2881 tgtaaggcgc tttaagaaca agataaggtt ttttacccaa gactgtctta aaacgactta
     2941 gacgagctat cagaggcttc ccccacctcc gttactgact tgtttttagc aaaggagcct
     3001 ttaggcgact gcgcagtaca atgtgagagc atagcgatca cactttttta gcgaccgtag
     3061 ggagcaaggt tttgaattgg cagttttgaa aaatgcgcga acctgttggt agaaaaaaga
     3121 agtggttttt aggcgggaaa ttttgtcacc ctcttttata atctcttttt aaaccttttt
     3181 ttaaacctct ttaccgtcgg ctgtgtcctt actccttcaa tggatacagc gttttataaa
     3241 ctacattttg tctgctttta aactacattt tgtctgcttt taaactacat tttgtctgct
     3301 tttaaactac attttgtctg cttttaaact ctttttttgc actcacgtat gttataatat
     3361 gcattatcac agacaaaacg ttgtttataa cgtctgtatc cattgaagga gtaaggagga
     3421 atatctttgg caaatgaaat cgtgaaatac catcatgaat taaataccat tccgttgcgg
     3481 aaatttacac cagttgaaat gaatctattt ttctctattg tgtctagaat gcgcgaaaaa
     3541 ggcgataaaa cagtccgtct tacttttgac caactaaaag atttaagtaa ttataaagca
     3601 actgctaata atcgtttcat taatgattta gaaatgactt atgataaatt aatggattta
     3661 cgttttggta aaagaagtgc taatgggctc gatatagata gattcgttat gtttagtgag
     3721 tttaaaatac gtggaactgc taaagatcca tatgtagaca tacaagttta cgaaaaagct
     3781 ttacctttac taaacaattt agatgagtgg gttcgctatt cactccaaca atttaacgaa
     3841 ttacaaagta gctatgcaaa gactatgttt cgattactaa aacaatatcg aactaaaggt
     3901 tttgcttatt tttctaaaga ggattttcat gaactattag atattccaaa aagttactgg
     3961 aacaaccaag caaacgttga taatcgtgtt ataaagccta tacgacagga attaaccgca
     4021 atcttcaaag gattatcaat caaaaagaaa tacggaaaag ggcgaggaaa acctgtcgtt
     4081 ggctatcaat ttacgtttaa accagaaatc aaaaaagcag atgattttaa taaacatgca
     4141 ccaaccaaag aagaacaaaa taaagcattg gctttagctg ataaacaaaa agaatacgaa
     4201 gaacctgcta caacaattaa cgaaaaaatc aaacagaaga aacgagaact tgaactcctc
     4261 caacaaatca aacaactaga aaaagagaaa gaagctcttg aaaaacaaac agagtccgca
     4321 ctttcgaaaa aagagaaaaa aagtttatta tctgatttag ataatttatt ccagtagcaa
     4381 cctaggaggc aaccagtatg caaccacaag aaacctttac aataaaggaa ttgtcagaac
     4441 tttttaagat gagtaggcaa gcaatatcga aacatatcca aaaattagat tcttccatga
     4501 tagctaaaaa tgagcgtggt tataaggttg tattgcgttc tggagtattg caacttgctc
     4561 gcaacttagg caaccaaatg ttgctagata ggttgcacga gtacgaacaa gacaacgata
     4621 aaaatgttaa tataccaagc aaaaacgtgg ttacaaacaa gttgctagat cagttgcgtg
     4681 aagaaaatga atttttacga gaacaacttg ccctcagaga gcaaaataat tctcatatac
     4741 aaaaactact cgaccagcaa caacaactca ccctacaagc caacaaacaa atcgaaaaac
     4801 tgcaagaaaa actacagttg acttatacag aagaagctcc agagaatgac tcaacgactc
     4861 tttctgaagc aacagaaaca atagacaaac aaattgatac tgaaaaaaaa tggtggcaac
     4921 tttggaaata actggaggga acattcatga caagaaaaaa tcttctattc ggttctattt
     4981 tactaggaat tctaggattc agtccgatgt tattgtcagt gatcaataaa gggaataaac
     5041 atggtgaatt gaaattgaat ccaaattatt acaacagtcc taacgaagaa ttgtttgtaa
     5101 aagaaacaga taaataataa aaaagactgc tctttcgagc agccagttaa aaaataatga
     5161 gtgtttattc ttgaaaaagc aacgcgctta tgaagcgcta ccaaaaattt atcatatttt
     5221 attaaaaata acaacccagt aaaaaatgac tggtaaaaat tcacaaagaa acggaaagaa
     5281 gcaaccgcag aaaatcaagc ttaaaaagag cttttgacct agaccaatcg aaaatcacaa
     5341 agtgagcgcc tgtatctatt gctacaggcg ctacttggca tagtgtacat tatgtcaaca
     5401 agaatttaat ataacatatt ttcctaatgc attctaacta taccacatta tcaaaaatat
     5461 aaattatctt tactaaataa aatattgaca agcctatacc ttttgtttta tgattttcac
     5521 aaagaaaacg ttttctatat atttttctgt atcaggagga aattctatga aaaaatttac
     5581 tttaggggta gctttgttaa ctattggggc agttgtttta ccgtcaacta ctatagttta
     5641 tgcttcagaa aattcccaag tggtatcatt aaacgaaaac aatgctactg aaaatgtagt
     5701 tattgagtac actgaagatg gtatggtcgt aactaaatat gaggatggtt atagtgcgga
     5761 agattttgca aattcttcag atatcatgac aagagctgca gttgcaagat ggggcaaaaa
     5821 ggaatataca aatattgctg taaccactgg agtagctgct aatgctatta atgctgcctt
     5881 ttgggcagga gggaaagcta gcacttctat gtttggtatc ccaggttggg caattggtgc
     5941 tttgttaaca ggtgcaagtt ggactaaaaa aggtgcttct ccagggaatg cagttgcaaa
     6001 agaatgggac aaaaatggta atggctggat tggattttat taccaaaggg gatatgatgc
     6061 agctggaaga gttgtagcta ctagatattc aacgttataa gttaaggagt gatgtttttg
     6121 atatctaaat cattaaaatc attaaaaaca tttactaaaa agaatccgca aatagctact
     6181 attcgtattt ttatatttgc tatagctgtt gctataattg ttaatatgct aagcggaggg
     6241 caattataca aatctggttt atttttagtg ttaatcttag ttgtcttaga cataataaag
     6301 tct
//
LOCUS       DACDLM010000112         6173 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.114, whole genome shotgun sequence.
ACCESSION   DACDLM010000112 DACDLM010000000
VERSION     DACDLM010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.114"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            725..811
                     /locus_tag="IV356_002691"
     CDS             725..811
                     /locus_tag="IV356_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011302749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HAP9016312.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="IV356_002692"
     CDS             complement(932..1621)
                     /locus_tag="IV356_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016313.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1628..1906)
                     /locus_tag="IV356_002693"
     CDS             complement(1628..1906)
                     /locus_tag="IV356_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016314.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(1866..2780)
                     /locus_tag="IV356_002694"
     CDS             complement(1866..2780)
                     /locus_tag="IV356_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAP9016315.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="IV356_002695"
     CDS             complement(2762..3142)
                     /locus_tag="IV356_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HAP9016316.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="IV356_002696"
     CDS             complement(3592..3879)
                     /locus_tag="IV356_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAP9016317.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="IV356_002697"
     CDS             complement(3899..4123)
                     /locus_tag="IV356_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HAP9016318.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4763..5296)
                     /locus_tag="IV356_002698"
     CDS             complement(4763..5296)
                     /locus_tag="IV356_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAP9016319.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..6159)
                     /locus_tag="IV356_002699"
     CDS             complement(5317..6159)
                     /locus_tag="IV356_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HAP9016320.1"
                     /translation="MREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEKILSL
                     RFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQF
                     NELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQEL
                     TAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALALADKQ
                     KEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLLSDLD
                     NLFQ"
BASE COUNT         1633 a         1151 c         1042 g         2347 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtgtatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DACDLM010000113         6132 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.115, whole genome shotgun sequence.
ACCESSION   DACDLM010000113 DACDLM010000000
VERSION     DACDLM010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6132
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.115"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(173..475)
                     /locus_tag="IV356_002700"
     CDS             complement(173..475)
                     /locus_tag="IV356_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016321.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(695..1061)
                     /gene="ssrA"
                     /locus_tag="IV356_002701"
     tmRNA           complement(695..1061)
                     /gene="ssrA"
                     /locus_tag="IV356_002701"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1232..2005)
                     /locus_tag="IV356_002702"
     CDS             complement(1232..2005)
                     /locus_tag="IV356_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP9016322.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            2149..2499
                     /locus_tag="IV356_002703"
     CDS             2149..2499
                     /locus_tag="IV356_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HAP9016323.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2480..3196
                     /locus_tag="IV356_002704"
     CDS             2480..3196
                     /locus_tag="IV356_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP9016324.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            3196..4644
                     /locus_tag="IV356_002705"
     CDS             3196..4644
                     /locus_tag="IV356_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP9016325.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4714..5223)
                     /locus_tag="IV356_002706"
     CDS             complement(4714..5223)
                     /locus_tag="IV356_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016326.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(5213..5938)
                     /locus_tag="IV356_002707"
     CDS             complement(5213..5938)
                     /locus_tag="IV356_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016327.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
BASE COUNT         2090 a         1062 c         1182 g         1798 t
ORIGIN      
        1 cttataattg gagtggtagt taattagtga cttatttttg attttatagc actgatacta
       61 taaaatatag atatcatcat attacacaat cttaatacta acttaaaaaa tatccctttt
      121 ataagtatgg tgataaaatc cgttccgggc tacctttttt aggtagccta ctttaatctt
      181 tatacctttc tggatcaacg aaagtatact tcaaatagtc ataacgccga tgatcgctcc
      241 gtgcgtctgg cacatcagtc acgatatcaa acaaaaaata cacatctttc ttcattctgg
      301 tttttgttgc cggaatttta aagtagttct tattagagta atagagattg attaataagc
      361 tatcttcgat tgctaaaaag aaaacttctg aatcccacac cttataaaaa tctttgacaa
      421 atctattcga aggatcaaat ttaaaccata attgtgtttt tccttccatc aacataatgt
      481 tcacctcaaa aagagtatac gaactaatgt tctttttgta aagtaggaat atcattgata
      541 atatggatgg aacatatata ttaaaaagtg ttctttttga atgctatttt gaatgccatt
      601 ttcattcatt taacgaaaat ctgcgaaaat aaaaaatgct caaaccctta taaaataagg
      661 atttaagcat ctagcgaaat ctgctgaaat ctcacaatgg agacggcggg agtcgaaccc
      721 gcgtccaaac acatcgccac ttaaaaatct acgttcatag tcaactcatt taaggattca
      781 ctttacagct tgccgagtga caggcattct gtatcgctag tctgatgttc tctttttcaa
      841 cttacagacg gaaagttgaa acgtatccca ctaaagttag gacccttact cgagcacatg
      901 ggcgatgccg agaggatcta cgctaactgt ttttaggcag ctaaagcgta agagttgttt
      961 tcgtttttag cagttatatt taactgtaac gtttttacgt agacgtaacc tacgaaacgc
     1021 aattcaagct cgactgtgcc tgtcgaatcc gtaacgtccc cgttagctaa caagggttac
     1081 gtgtattttt catacaaaat tagtatagca tatattggga taaattcaat aaaaaagcga
     1141 atcatatccc attatttata taataactgc ccctttctta agaaaaaata agcgattttc
     1201 ttaagaaaag aggtagcttc aaaaaaagat cttaaatcag atcaaaatac ttcaatgcgt
     1261 ggacaattcc gccttctgta tttttctttg tgataaaggt agaaagttct tttaatccgt
     1321 cataggcgtt gcccatagcg attttgttgt cgcaagcttc caacaaggca aaatcattcg
     1381 gaccatcgcc aaatccaaaa gtaggaactt tttccagctg aagttctttt tgcagacgtt
     1441 tgacacctgc cccttttgag attcctttct tcactgtatc gatcgagtaa ggaccattcc
     1501 gataaaaagt tagctcagga aaatgttcgt gatagtattc gtcacctgat tgagataaga
     1561 tcagcaacat atttactgtg ttttctttaa agcctaaagg atcaatttcc ggaacatctg
     1621 aatgaatgaa gtcgtaagca ttgatcattg tttggctatg accggtacac cagattttct
     1681 gatcgttata gtaagaaagt tcatgaccgt tcaactgtac atgatcatac attttttgac
     1741 attcttctga agaaaatgtt tgagaataga tttcttcgcc gtctactcga atgaaagaac
     1801 cattcatggt gaccgcagaa gtaatgcccg catcttccat gatagagtgg atttctgctt
     1861 ctgtacgtcc tgtagcgatg acggggagaa cattgttttc ttttaatgcg ttcatagctt
     1921 ttgccacttc gggtgtgatt tttgatttcg catctagtaa tgttccatca agatcaaaga
     1981 aagtgattgc acgataattt gacacaaata aaactccttt tttattggaa taagtttatc
     2041 ttaacaaaga atgaacaaaa gacaaacctt tcgtgaagaa ttcctgaaca tattggttca
     2101 gtcaacaatt tagagtatac tataagaaga gaatttagga gggaaagaat gatttttttc
     2161 agtattggta tcttattctt aataattggc agtctttttc ggattctgcc ctcaaaagga
     2221 aatctgcctt tttatgggta tcattcgcct cttgccgcaa aaacagacgc tcattggcgg
     2281 ctggctcaaa agacaagcgg aaactggttt tttcttatgg gcttactgat ggcattgatc
     2341 ggctattatt taaagacatc tgggcatacg aattattttc tgattgaaat gcttctgcta
     2401 gtatttccaa ttatgcctat ttttattatg acagaaaaga aattacagaa atatgacctg
     2461 gaaactggag ggaacgataa tgaatatttt aatgattgaa gataatcaat ctgtttctga
     2521 aatgatgcag atgtttttct taaatgaagg ttgggaagca actttcaagt atgatggaaa
     2581 agaagggctc gatgcctttt tagaaaaccc acaacattgg gatatgatta cactagacct
     2641 gaatttgccc acactggacg gtatgctagt aggaagagag atccgcaaag tttcaagtac
     2701 tgtgccgatt atcatgctga cagctagaga ttctgaaagc gatcaggtga tcggcttaga
     2761 gatgggggca gatgattatg tcacaaaacc tttcagtcct ctgacgctta ttgctcgaat
     2821 gaaagctttg catcgccgta gtgagttggc agaagcaaga gaagaagcag tagtttcaga
     2881 tgatcatttt gatatcgaga ctagtcattt caagatgaat acgaaaacac gagaagcgta
     2941 tctggacaac cggccaattg aaggactgac gcctaaagag ttcgatctat tgtttacttt
     3001 agcaaaaaaa ccacgtcaag tattctctcg ggagcagttg cttgaattag tctgggatta
     3061 tcagtacttt ggtgatgaac ggacagtgga cgcccatatc aagaaattac gacaaaaaat
     3121 cgaaaaggtc ggaccacaag tcatccaaac tgtttgggga gtcggctaca aattcgatga
     3181 ttctggtgtt gcctaatgcg ttatttgtat cagcaactct tagctttctg cggaatggtc
     3241 gcgttgatct tattgatcgt tggagtttct tttacacaac tgacaaaaca aacgattgaa
     3301 gaaaacaatt accagcaact gtttggatat gctgaatcag ttgaaaagac aacgcaaacc
     3361 tatgccgata cgctcccgca gtttagtcaa gatcaggcgt ttcaaaatgc attgctgctg
     3421 acagagcaag tactgacaga acaaaatgtg aactttatat ttatcgataa aaacgaacgt
     3481 gtcatttatc cgactaatac agctttactg aattttacct taacagctga tcaatggaaa
     3541 aatctgagga atggacgtca agaaaaattc acatcgaata aaaatatttt aggacaagca
     3601 caggcgacct cttacgcact tgtgccattt aatttgaatc atgaattcta tggagcactt
     3661 gtagttagtc aacctgcgcg aaatatcgat aacagcgttc gtccaattac actgaacctg
     3721 ttcaaaggat ttattttttc cagtatcgtt gcagttattg ccagctatgc ttttgcagca
     3781 ttccaagtta agcgtatcaa tcggttaagg aatgcgacga aagaagtgac gaatggtaat
     3841 tttgatgtac agctccccgt acatgacaaa gatgaatttg atgagttagc agatgatttc
     3901 aataaaatga cgaattcatt gaaagaatct caagcagaaa ttgaagaaca agaaaatcgt
     3961 cgaagacaat ttatggcaga tgcttctcac gagatgagaa cacctcttac gacaatcaac
     4021 ggacttctgg aagggttaga atacaatgca atccctgaaa atcagcgaga aaacgcgatt
     4081 aaattgatga aaaatgaaac agagcgtctg atccgtttgg tgaatgaaaa cttggattat
     4141 gaaaaaatcc gtacgaatca aatcagtatg gtcattaaaa aattcaatgg aacagaaaca
     4201 ttgaaaaata ttgttgcaca gttagaagct aaagcagaag cagcaggaga tacattgaca
     4261 ttgaaagccg ttgatgatat tgatgtttac gctgattatg accgatttgt ccaaatcatg
     4321 gtcaatatta ttcaaaacgc gatacagttt actgaaaacg gccaaatcac gattacttta
     4381 gaaaaaggct atcttgaaac gatcatcacg attgaagata cgggaattgg aatgtctgaa
     4441 caacaaatga aaagtatctg ggatcgttat tataaagtag atccttcaag aaaaaataca
     4501 aaatatggtg aatcaggatt aggtttacca atcgtgcagc aacttgtacg cttgcataaa
     4561 ggaaaattag aagtagaaag cgaactagga aaaggaacaa aattcgctgt tcgtttgcct
     4621 gacgtagaaa tcaaaaaaga gtaaaaaaca agcggtataa aagatcatga atcgatcttc
     4681 tataccgctt gtttttacta taaaatgatt gatttagccc gcgggctcta aacgatcaat
     4741 ataaggactt tgagcaatag tagcatcatg agtaaagagt aagatacctt gattttcttc
     4801 atgagctaaa taagaaagca agtggagtag ctcttggatc tccaatacac taagttcatc
     4861 aaatgtatct tcaataacaa tattgtttcg cttggaaagc aaggcatgaa gtaattgcag
     4921 ctttactttt tcaaaagacg tcaactcagc tgccgcacaa ttaagcaagg aaggagagat
     4981 atcaagtttt tcttgatagg ccaaacgatc ttgtttgatt tctttttccg gtacatccaa
     5041 caggacatgg tctttaagat tcagataagg aaacatcggc caattttttt ggatgatcgc
     5101 aaaattatcc agttttgcaa caagaacctc ttttttcaag tgctccaata ttttatgctg
     5161 tttttcgaga ggacacaaaa taacggtcaa gtgttcagca tgaatcaaat attcaggttt
     5221 cattacgtcc aggcctccta ctttgcaaat gatggataaa aaaagtgaaa gggaatagac
     5281 taagaatgag acagcatcca ctgagcccaa taagagtttg ggcaaatccc ttaagtatat
     5341 ctgtgaaaaa aagatcattt tggaaatcga tggtaaaaaa agtctgttga tccatcggaa
     5401 ttgtaagtcc gcttaccgaa gtcaagatat cacggatatc tggcagttca gtagtcttta
     5461 agacaagaaa attgatcctt tgaagaagcg cttcataaac tgactggaag cttacgatcc
     5521 acaataaaac caagatacaa caaagaaaga gaggaaagaa cagctgccag aaaataaaaa
     5581 ggaataattt ggttttagaa agaccagtca ggtgccaatt gatcaattcc tgcttgtttt
     5641 gcctgactga atagtaaaag aaaaagataa aaaggaaggc aaatagaaaa aataaactga
     5701 atatgccttt tatataaaat cggctagcta attctaaagc cggaagaagc tctgtagatg
     5761 cagaagcgcc aataaatgaa agccgatctt ggacttgatt ggctaaagcc gattgcaaat
     5821 ggtaaagagt caggcatgct atcaataaaa aagcagaaaa gcttgaaaat aaacaataga
     5881 gtattgtctg ctttttgtaa taaattaatc gagcagtagc atagcggatt attttcatac
     5941 ttttcacctc tataaaaagt atagaaaatg aatatgaata aagtatgaaa ttcctttagt
     6001 gaaatcacga attaaaacca gaaaatattt tgtaaaaagc aagaggttgt gaagaagctg
     6061 ccctattcta ttaccgtaga tgcaagcttt tgaacactgt ttattcgaaa agaggagcag
     6121 cgacaataat tt
//
LOCUS       DACDLM010000114         6116 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.116, whole genome shotgun sequence.
ACCESSION   DACDLM010000114 DACDLM010000000
VERSION     DACDLM010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6116
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.116"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            173..1477
                     /locus_tag="IV356_002708"
     CDS             173..1477
                     /locus_tag="IV356_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP9016328.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEDTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            1573..2442
                     /locus_tag="IV356_002709"
     CDS             1573..2442
                     /locus_tag="IV356_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP9016329.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(2554..2874)
                     /locus_tag="IV356_002710"
     CDS             complement(2554..2874)
                     /locus_tag="IV356_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HAP9016330.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            3044..4003
                     /locus_tag="IV356_002711"
     CDS             3044..4003
                     /locus_tag="IV356_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP9016331.1"
                     /translation="MTYTHLTPTELVMIEAYFNQSHSVSKVAHLVQRSRQTIYNVYRF
                     LKSGGSAISYYEQYKKNKRNCGRRPIVLPDGQQEYIQKKVAQGWTPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDPHDLPMKGKRKPNGHKEKRGKQAFRRSIQDRTTDYIQFNHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPAGRQAIDIENRLNQWFQSVPKHLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNK
                     VSETFIQSVASKRNHIPRKSLHYRTPLEVFLSYVGKDDLSSLI"
     gene            4093..4488
                     /gene="dhaM"
                     /locus_tag="IV356_002712"
     CDS             4093..4488
                     /gene="dhaM"
                     /locus_tag="IV356_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HAP9016332.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            4490..5473
                     /gene="dhaK"
                     /locus_tag="IV356_002713"
     CDS             4490..5473
                     /gene="dhaK"
                     /locus_tag="IV356_002713"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HAP9016333.1"
                     /translation="MKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRVVAKNQKAEQ
                     VGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEADSGKGVLLIV
                     KNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAGTVLVHKIVG
                     DAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDEIEYGVGIHG
                     EPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQFVFMNDVLA
                     LLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTISW"
     gene            5501..6106
                     /gene="dhaL"
                     /locus_tag="IV356_002714"
     CDS             5501..6106
                     /gene="dhaL"
                     /locus_tag="IV356_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HAP9016334.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
BASE COUNT         2055 a         1103 c         1325 g         1633 t
ORIGIN      
        1 atgaagatga aaaattgaaa aaaagacaag aattacttga agaagtgtat acggaacgtt
       61 ttggaacaaa agaagagaga gaaacggtcc gtttttattc tgtctccgaa gagaaaaatc
      121 tagatacgac attcattgca gatttgtata aagaaaatgg ggtggaactg aaatgatctc
      181 aatcacccat acaggtaatt tattcttaga tacttgtttg tctattatgt atttttttct
      241 cgtttcttat ccgattttag gcggatttgt atggtttatt ggtgtctggt gttatgtgtt
      301 tttatacaaa cataagcaaa aagaatgggt agatgttccc ttgagtgtcg aaccgttcat
      361 cacgatcatg gtgccagccc ataatgaaga aattgtgatc gaagatacaa tcgagtattt
      421 gatgacgaaa ttgaattatc acaactatga ggtattagtg acagacgatg gttcaacgga
      481 ccaaacacca gaaatattag ctagactgat gaaaaaatac gctaatcttc gtgtggttcg
      541 gatcgaaaaa aataaaggaa aagcccacgc gtttaatatc ggacttgcct ttgcaaaagg
      601 gaaattgatt ttaagcaatg atgcagacac ggtaccggag ccagatgcac tgattaggta
      661 tgtgaattat ttcattcgcc ctggtgcaag acatattgct gcggtcactg caaatatgga
      721 tgtccaaaat cgtaccaaat tgattgcaaa atctcaaacg gttgaattct caagtatcgt
      781 gggcatcatt aaacgaacac agtcagctgt tttcggtggt ctttatgcgt acagtggagc
      841 aaatacgatg tatcgaaaag aagccttgat cgatgtgggc ggattcagac aagatcgagc
      901 gacagaagac atcagtattg cttgggatca tcagttaaat gactggttat ctgtttttgc
      961 tcctgagatt atctttttca tggaagtacc tgtgacgttg aagatgctat atcgacacag
     1021 aaaacgttgg gcaaaaggtg gaacagaagt ctggctgacg aatttcaaaa aagtgatgct
     1081 ccatcctttt aaacatattg gaagaacgat catcttcatt gatcaaacat tgagtattgt
     1141 ctggtcaata ttcttttgta tttccgtagt tctttttgct ggattaatcg ggcattatgt
     1201 atatcaagga aactacgaac agatttatat tacttttaca ttcagttttg tgttcatctg
     1261 ctttgaaatg gtcgcaggat ttttccagtt gctagcttcg ctgattgtag atgatcgacg
     1321 aagaaaattg aaataccttc ttttcgcacc actatatatg cttttgttct ggatagtgaa
     1381 cgcgataacg atcgtgacga ctttcattcc agcagtcaaa acgattttag gttatggaag
     1441 cgggacatgg aaaagcccgg aacgtacaaa aaaataaaag atgcaccgtt ttttagacaa
     1501 acagcctgtt gtgtttatgg ttcttccaaa catttttgct tataataaga aattagttaa
     1561 aaagtagtaa ggatgggaaa agtgatgaaa aaaagaatga agccgttaat ctggccaatt
     1621 gctgtttcca gtattttctt attgggacag acagcttttg cggaaacttc tgaacctgct
     1681 caaacagaac cttcaacaac cataagctct tctggtgctg aaaacggtgc ctcggaaaca
     1741 gaaatgactt ccaatgtacc gacagataat tcaggagaaa cgatttcatc ttcagaagat
     1801 acatcaataa atagttctac ctcttctgac caaatcgatc atttgcaaga cttggaaaat
     1861 aaaagaaaag aactcgaaga agcattagaa gctgcaaaaa acaaattgaa agaagaccaa
     1921 gcagcaatcg atcaagattt agctgatctt aaaaataaag tgggaaatga ccgtgcacaa
     1981 cttgagaaaa agcttgccga agcgaaagca aaagcggaag ctgtccaaac agatcttgac
     2041 gggaagatcc aacaagcaaa agaattcaat cagcaattaa atcaggttgc tcaaacagct
     2101 tctggaaagc taagtcaaac tcaagcggat atcacagcgg ccagtcaagc aatccacgga
     2161 aagatcagcg aagcacaaac agttgctaat gattttgaag caaaaaaagc tgacttagca
     2221 gctagtttcc aacgaataaa agatattttg cattcggcag gagaaaaatc agtgacctct
     2281 ggaagcacga cagaaacagt tcagcaaacg acagagccat ccaaatcaac aagtcagact
     2341 ttgccaaaaa caaatgaaaa aacagcttct gtcagttatt ccttagcagg ggcgggtgtg
     2401 ttagtcgcag cagcttacgg aatcatccgc aaaaagaaat aaaaaagaga ggatgggaag
     2461 gtagagtacc tcgaagttag actgaaaaat ctaattcttg agtgccacta catgtcccat
     2521 ctctctttag ttattaaaac agatgtcccc tacttatctc gtggagacag ctgttccact
     2581 acatgtgacc atcagcatgc cattgtcgct gcctaatact tcatagtcca tttttacgcc
     2641 aatgatcgca tcagctccta atgcttttgc acgttcggcc atttcggcaa gtgcttcttc
     2701 tcttgcaccc attagttcgt tttcatagct ttttgagcgg ccgccaaaga tatttcgcaa
     2761 ccccgcctcc aagtctttaa atgcatggat cccagtaatg acctcaccaa aaacgatccc
     2821 tttataagct actacggctt ttccctctac actgttcgtt gttgttgtaa tcattcgatc
     2881 actcctctct tttaattaaa gtataacaaa cttcaagaag cactacacat attttcccaa
     2941 aattagaaat cgccgattgt aaaattaagc tagacaacta aaaaagtcat ttgtgctaca
     3001 ctcaaaatag ttccgtcgaa agaattataa ggagtgagta caaatgacct atacccatct
     3061 tacaccaact gaactcgtaa tgatagaagc ttatttcaat caatcacact ctgtttcaaa
     3121 agtagcccat ctggtacaac gttctcgaca aaccatttat aatgtctatc gttttcttaa
     3181 atctggtgga agcgcaataa gctactatga acaatataag aaaaacaaac gtaactgcgg
     3241 aagacgtccg attgtgttac cagatgggca acaagaatac attcaaaaaa aggtggctca
     3301 agggtggact ccagatgtcc ttattggtcg agcagagttt cctattgctt gttcggtacg
     3361 tacactatat cggatgttta aagataaaac ctttgaccct cacgatttac caatgaaagg
     3421 gaaaagaaaa ccaaacggac ataaagaaaa aagaggaaaa caagcttttc gccgttcgat
     3481 tcaggataga acaactgatt atatacagtt caatcatgag tttggtcacc tagaaggtga
     3541 caccattgtc ggtggaaaac ataaaagtgc ggtgatcacg ttagttgagc gattatctaa
     3601 agtgatcatc accttgaaac ccgctggtag gcaagctata gatattgaga atagactgaa
     3661 tcaatggttt caatctgtac cgaaacactt gtttaaatcc atcacatttg attgtggaaa
     3721 agagttctcg aattggaaaa agattagtaa taccaatgat atttcgattt atttcgctga
     3781 tccaggaaca ccttctcaac gaggactaaa tgaacattcg aatggcttat tacgtaaaga
     3841 tggcttatat aaagctatgg attttaataa ggtatccgaa acctttatcc aatcggtggc
     3901 atcaaaacga aatcatattc ctagaaaatc attacactat cgcacaccat tggaagtatt
     3961 tttgagttac gtaggtaaag atgatttgtc tagcttaatt tgacaaacga aaaatttatt
     4021 atatacttga attgttcatt aatgaaagcg aaaccaatcg ttagcaacta tgtaaaagaa
     4081 aggaagattc ttgtgaaaaa aagtattttg cttatttctc atagtcaaaa agtaacagat
     4141 ggtattaaag aaatgattga gcagatgcaa aaatccgaag aggtgcaaat tttttctctc
     4201 ggcggaataa atggcgagat cggatcagac ccgatgaaaa tcgtagaagc agtcaatgaa
     4261 tcaagcgatg cagctagtta ttttgttttt gcggatatcg gtagcgcggt attgaactcg
     4321 gaactggcaa aagacatgtt ggaagaagag cagcagcaac gttatcatct ggtggatgcg
     4381 cctttagtgg aaggagcttt tgcagcagcc atcactgccg gtataacaga tgatactcag
     4441 caaatcttaa cagaagcaca aaatgccgga aagaaaggat gggaataaat tgaaaaaaat
     4501 catgaatgat ccaagcaata ttgtcgaaga aatgctggaa ggattagtaa aaagctatcc
     4561 agaacttgtt catcgtgtag aatcttcccg tgttgtagcc aagaatcaga aagcggaaca
     4621 agttggtttg gtttctggtg gaggaagcgg acatgaacca tcccatgccg ggtttgtagg
     4681 ggaagggatg ttaagtgcag cggtgcttgg tgatgtgttt acttctccaa ctccagatca
     4741 gattcagacg gctattaagg aagccgatag tggaaaagga gttttgctga tcgttaagaa
     4801 ttatacaggg gatgcattga acttcgatat ggcaaaggaa ttagctgcta tggacgatat
     4861 tgaagtagaa agtgtgatcg tagatgatga tatcgccgtt gaaaatagta cgtatactgc
     4921 tggaaaacgc ggagttgcag gtactgtcct tgtacacaaa atcgtgggcg atgcagcaag
     4981 aaacggtgct tccctagctg agttgaaaga actgggagaa aaggtcgtac aggcaactaa
     5041 gacgatcggt ctagcgcttc gagcagcaac tgtaccagaa gtagggaaac caggattcga
     5101 actaggagaa gatgagatcg agtatggtgt tggtatccac ggtgagccag gctatcgtcg
     5161 agaaaagatg cagccttcta aagtactggc aaaggaactt gttactaaga ttttagatga
     5221 ttactcgaat ttaccaaaag aagcaggtgt actagtcaac ggaatgggcg ggacgccttt
     5281 gatggaacag ttcgtgttca tgaatgatgt tttagctctg ttggaagaaa gaggcgtcaa
     5341 tgtagttttc cgaaaagtcg gtaattttat gacctcacta gatatgcaag gtctttctct
     5401 aacactgatc gacttgacgg agacacaatg gaaagattct ttagaaagca atgtacagac
     5461 gatttcatgg taaaaaatct caagataaaa gggtgataat atgaaactaa ccgttcaaga
     5521 aatccaagaa tggctcacgc aatttgcaga ggcaatcaat cagaacaaac aatatctcag
     5581 tgatctagat accccgattg gcgatggaga ccatggaaat aacatgggaa gaggggtttc
     5641 agcttatgaa gaagcttttc aagccgatca tcctgaaaca atcagcgata cattcaaagt
     5701 attctctatg gcgatgatat cgaaagtcgg tggggcttct ggtccgttat acggatctgc
     5761 attcatgaac atgatgaaag cgacaaaaga ggtcgattct attgattctc aagaaaaatt
     5821 aggcgaagtg atcgagcagg gaacagcggg tattcaaagc cgaggaaagg cagaagctga
     5881 cgataaaacg atgttagatg tttggctgcc agtcacagag gcattgaagg cagggaattt
     5941 aacaaaagaa atcattgacc aggcaaaaga acacaccaaa gtcttggtag ctaaaaaagg
     6001 acgagcttcc tatctaggag agcgtgcaat cggacatatc gacccaggag ctgcttctag
     6061 tgccatttta ttttcaacgc ttttagatgt gatcaatcaa ccttaagttc aataaa
//
LOCUS       DACDLM010000115         6090 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.117, whole genome shotgun sequence.
ACCESSION   DACDLM010000115 DACDLM010000000
VERSION     DACDLM010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6090
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.117"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(302..787)
                     /locus_tag="IV356_002715"
     CDS             complement(302..787)
                     /locus_tag="IV356_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016335.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(926..1141)
                     /locus_tag="IV356_002716"
     CDS             complement(926..1141)
                     /locus_tag="IV356_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HAP9016336.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            1365..2165
                     /locus_tag="IV356_002717"
     CDS             1365..2165
                     /locus_tag="IV356_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP9016337.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            2184..4052
                     /locus_tag="IV356_002718"
     CDS             2184..4052
                     /locus_tag="IV356_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP9016338.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKVGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            4045..4536
                     /locus_tag="IV356_002719"
     CDS             4045..4536
                     /locus_tag="IV356_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HAP9016339.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            4524..5078
                     /gene="srlA"
                     /locus_tag="IV356_002720"
     CDS             4524..5078
                     /gene="srlA"
                     /locus_tag="IV356_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174078.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HAP9016340.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            5096..>6090
                     /locus_tag="IV356_002721"
     CDS             5096..>6090
                     /locus_tag="IV356_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HAP9016341.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVPTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2151 a          968 c         1221 g         1750 t
ORIGIN      
        1 aataataaga agaaaatatg tcaaaaggta aaaaagtaaa ttcttctatc caaatataga
       61 aaaattgaat ctagaaaacc gcccgacaat aaatttcatt aactcagttg accgaaaatg
      121 aagtagatac caaaaattta tcaagagagc aagtagagaa gtgagtatat tcataagaga
      181 aatagctgta acgaattatt aggttaatgc aaatgcttat ttatactccg tataactttc
      241 tcagaaaaaa tgataccaat aatgacttgc tagtactgta aatccgtata atatcatcta
      301 atcaaaatgg tgttccattt gcatctgtca tcgtaatcga tccttcgggt gacactcgat
      361 aaaaaccaac gcttccagat cctccttggg aacggatttg tttgctggaa gctgtgaaca
      421 aataatctcg atcaattttt tgataaaagc taataacaat atcgtcactt tgtaattcgg
      481 aacggtgggc aataagaaat agaagtgctt tgtcagagtt ttctaatgga agagaaggta
      541 cagtgctttc ttgcatttca gatgttgaag aaatgctaaa cgactgaata cttgattggc
      601 tatgttgcga atctacatta ccagtagaag tattagtaat ggaagtagta gaagtacttt
      661 tagttgaacc aacctcagtt gttgaaatgg ctgctgaaga ttctttaaca gaattctttg
      721 ttttatatcc acaggcagaa aaaagtatta cagttcccaa caagcctgcg taaatccctt
      781 tatgcatgat agctcctcct aaaatagatt atctttattc agtatatcac ttaaacaaag
      841 aaaagcagat ggtttaaaat gaaaaaacct tcccaataaa gggaaggttc atgaagataa
      901 taactttttt aataattata gctttctaat atctttcatc aacttttcta gtaatcattg
      961 ggaaaaattt caagcagtag atcgcacaaa tacctacgac gatataaatg atcttcgcaa
     1021 aaatagttgt tgaaccacca gcaatcatag ctactaaatc aagttcgaac aagcctacca
     1081 acagccagtt caaccctccc acaatcaata aagttaatgc aatagcatct aaagttttca
     1141 ttagaattct cctttcttaa atgataaaac aattatatat caaaaagaga aacattgctt
     1201 atataacgct caggaatttt agcaatctat gcaaaaagat gaaaattttt tttgctcttc
     1261 cattagtaca cattttttag ctgaagctgt aaatttcatg tcttaatttt ttttagtgag
     1321 cttttatact ggatttgtaa gaaaaaagaa ggagaggatc acatatgtcg gattggttgg
     1381 atattgcagg aaaagtagta attgtaactg gaggttcctc aggaattgga agaagtatcg
     1441 tcgaaaattt gttgaagcag aatgcacaag tagcgaattt tgatgtaact gaatgccgta
     1501 tacagcatga aaacctacta tctttaaaag tcgatgtgtc ttctaaaacg gacatagaag
     1561 aagggatata taaagtaatg aaacatttca agacgatcga tggtctagtc aataatgcag
     1621 gaataaatat tccttctctt ctaatagata gaaatcatcc aaaaagcaag tatgaattat
     1681 cagaacaagt ttttgataag atgatcgctg tcaatcaaaa aagtgtatat ttgatgagcc
     1741 aagcagttgg aagaatcttg gtgcaaaagg gatcaggagt gatcgtgaat ctttcttctg
     1801 aatcaggatt ggaaggatca gaaggacaga gctgttatgc tgctacaaaa gcagcgatga
     1861 acagttttac tcgttcttgg gcaaaagagt taggaaagag gaatgttcgt gtggtaggtg
     1921 ttgcaccagg gatactggaa gaaaccggtt tgagaacaca agaatatgaa gaagctcttt
     1981 cttatacgag aggtataagc gtcgaacagc tgagaaacgg ttacagtcga acaagtacga
     2041 tccctctagg aaggagtggt aagctgcaag aagtggcgga tctagtctgc tattatcttt
     2101 cagaaagatc aagttatatc actggagtca cgactaatat ttcaggaggt aaaacaagag
     2161 gataaaggat aggggggacg cacgtgacgc tagtaaacag atggtaccaa ttattgaaat
     2221 tactagtcac tcacaagaaa gtttcaatcc aggaagtgca aaaagaaatc aaaaccagta
     2281 atcaaaccat aaaaaaagat attggggagt tgaatgaaga aattgccggt attgcaaaaa
     2341 tcatccaaaa aaacaaacat tttgaacttg aaatttatga ttttgatttt tttgatgaga
     2401 tcatgcaagg aaaattgaaa acagccagtg atttcaattc ggcatccaaa agaatcgctt
     2461 atttactaaa taggctgatc gaaacagagg atttcttacg tatggatgat ttgtctgaag
     2521 aagtcggtgt cagcagagga acagtggtca aggatctaaa gacattaaaa gagatgatca
     2581 atgattttga tgtaaagatt acaggcacac caaataaagg actaagaata ataggagatg
     2641 agctagaatt acgactactt ttattttatt ttgtttctcc ctacttttca gagacgaaaa
     2701 cagaacagtt tctagaagaa aaacaagcaa tcaaacattt tcagaagaag acgaatgcta
     2761 gtaaacaaga aatcaccctt ttaacgaaag ttatcggtat ttctttgaat agaatctcta
     2821 gtaactatct gttgaagaag cccatcaatc gttacagtgg gtgttttgaa tatatccaag
     2881 aattcaatga actgatcaat cagttggaag aaatctatga actaactttg agccaatatg
     2941 aaaaagattt tatcagtttt cctttgaaca tcatcaacac aagtataacg atgataagga
     3001 aagctaactc tgatttgcgc ttatatttcg accccatgat gatgcgtatt cgacgattag
     3061 atctcattga tctggatgag tccttcttat atcaagagat gaaacagcac ctctctttat
     3121 tgataaatcg ggtaattttt cgttatcgat tgactgattt attttatggt gagatagaaa
     3181 aaaagtatcc tttttcttac caaatcgcta gcgaatgcat acaagcatta gaagctatct
     3241 tgcaacataa gatctctaaa gtagagatca gctacctaac gttgtatttg gagttagcat
     3301 ttcgatatca aaaagagcat ttttcctcta aaaaagtagc cattgttcat acgacaggaa
     3361 aaggaacagc attaatgatc caaagacaaa tcaaaaggat attggggagg gatatacaaa
     3421 taacacatgt ttcagaagaa caatatgaaa aagtagatct aaacaaatat ttcgctgttt
     3481 ttacaacgat tccgttaaaa aatgtaaatg aagagacacc ggtgatccat ttgactaatc
     3541 tttttgatga ctcttggtta agggcacaat ggcaaaaagc aaaaaaaaag cgattagccg
     3601 ggtttcattc tactgttttt ttctatcaaa tatggaaaga aaaaaagacg tatcaagaat
     3661 atttaaacaa attagtcgct cctttgatca gaggctatta tgtggatgaa gaatttgaaa
     3721 aaaggatctt gaaaagagaa tatcagcaaa gcacatttgt taacaaagaa tttgcttttc
     3781 ctcacacaac caaccagcta tctcaacaca ttgttttatc agtagggcta ataactgatc
     3841 aaggtttagc agaaacagga ggaaatggag ttattttttt atttgccata cctgaagaaa
     3901 tgacggctga agttgagaat gaattatttg agctatacga tatcctattt gaactcataa
     3961 aagtgggaat agatgagttt attgaattag caccgacaca agaatcattt ttaaaactaa
     4021 tcaaaagtaa aggagagaga cttcatgaat gatatgtatc tattcatagt tttcgcagct
     4081 tcagcttatg tgctgcaagc agttatcagt tggaagcaac taaagcattt caatcaaaca
     4141 tatagcgaac tgcgaagaaa aggaaaagta gcgattggta aacgacctgg gaaaatccgt
     4201 tcaggcacga ttgttatgct agctatagac gatcatgatc aagttttaga agtcagaaaa
     4261 atgcaagggg ttacatcttt ggcaaaattt cattcattac ctgtctatgc gggtgaagat
     4321 atccattaca tcgatcgtta ccatccctca gttcgagcgg aagatcgttt gacacaagca
     4381 gctttagaaa atgccagaga agtatactta cgaatagagg caggaaatga aaaaagtgaa
     4441 caaccttcat tgccttttat tgctatgctc aataattttc ggatatggaa aagtacgatc
     4501 aaagaaaaaa ggagtgacaa acgatggata tcataacaaa atttgctgag ggatttatga
     4561 ggctgttcca aacaggtgca gaaacattca taagctggat gacaggaatc gtaccagttg
     4621 tcttgatgct gatggttgca atgaatacgc tgattgcttt tttaggtgaa gaccgagtaa
     4681 cgaaagtagc caaattatca gcgaaaaatc cgcttactcg ttaccttgtg ttaccgttct
     4741 tatctgcttt tatgttggga aatcctatgt catttacaat ggctcgtttc cttccagaat
     4801 actacaaacc aagctattat gctgctcaag ctcaattttg tcatacgagc aatggtgtat
     4861 tcccccatat taatcctgga gaattgtttg tatggatggg gattgctcaa gggatcgaaa
     4921 ccttagggct aaattcgatg gagctggcta tccgatactt gcttgtggga ctgctgatga
     4981 actttattgg tggttggata actgatttta ctactggatt tgtatgcaga cagcaaggaa
     5041 tcgttcttag caaaaaagta gagctttcag ttgattagag aaaggagagt tttaaatgta
     5101 tggtgatatt aagatcgtaa gaggaaacgg cgggtatgga ggtcctttga ttattaggcc
     5161 gacaaaagat aaacacaagt tcatctatgt cacaggtgga ggtgagaggc caatgatcgt
     5221 agataaaata gaagaactga caggtatgga gtctatcaat gggttcaaaa catcaatacc
     5281 tgatagtgaa atcgcgcttg caatcgttga ctgtggaggg actcttagat gtggaattta
     5341 tcctaaaaaa gggataccaa ccatcaatat cgttcccaca ggaaaaagtg gcccattagc
     5401 acaatatatc actgaagata tttatgtttc agcagtaggg ttagaacaaa tacagccact
     5461 aatggaaact gatgataaca aagaaacagt aaatactgca tctccagata aaaagtacaa
     5521 atatgatact tctaaaaaga taaccgagca aaaagcagag cagcaaaact ggatagcaaa
     5581 aattggaatg ggcgcgggaa aagtagttgc tacattcaat caatcagcaa gagaagcagt
     5641 agatacgatg atccggacag tgatcccttt tatggctttc gtttcccttt tgattggtgt
     5701 gatacaaggt tctgggatcg gtaatgtatt tgctaacatt atggcacctt tagcaggaaa
     5761 tgcagttgga ttaacaatca ttggctttat ttgttcactg ccatttttat ctcctttgct
     5821 tggtccaggg gcagttatta gccaagtgat tggaacattg atcggtgtag agattgggaa
     5881 aggaaatatt cctccccaat tagcattacc ggcactattt gctatcaata ctcaaaatgc
     5941 atgtgatttt attccagtcg gtctaggttt ggaagaagca aaagctgaga cagtagaagt
     6001 aggtgtacca tcagttcttt attcaagatt tcttaacggc atcccacgag ttatcattgc
     6061 ttgggtagca agttttggat tatatagctg
//
LOCUS       DACDLM010000116         5973 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.118, whole genome shotgun sequence.
ACCESSION   DACDLM010000116 DACDLM010000000
VERSION     DACDLM010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5973
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.118"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            5..862
                     /locus_tag="IV356_002722"
     CDS             5..862
                     /locus_tag="IV356_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP9016342.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            884..1393
                     /locus_tag="IV356_002723"
     CDS             884..1393
                     /locus_tag="IV356_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP9016343.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            1430..1831
                     /locus_tag="IV356_002724"
     CDS             1430..1831
                     /locus_tag="IV356_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016344.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            1943..2296
                     /locus_tag="IV356_002725"
     CDS             1943..2296
                     /locus_tag="IV356_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016345.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            2330..2773
                     /locus_tag="IV356_002726"
     CDS             2330..2773
                     /locus_tag="IV356_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAP9016346.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            2790..3875
                     /gene="uxuA"
                     /locus_tag="IV356_002727"
     CDS             2790..3875
                     /gene="uxuA"
                     /locus_tag="IV356_002727"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAP9016347.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            3868..4581
                     /locus_tag="IV356_002728"
     CDS             3868..4581
                     /locus_tag="IV356_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP9016348.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            5333..5533
                     /locus_tag="IV356_002729"
     CDS             5333..5533
                     /locus_tag="IV356_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP9016349.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         2084 a          901 c         1295 g         1693 t
ORIGIN      
        1 ggaaatggct gaaataatgg ataatcaaac aggtgctcct gaagaaatca cgaaaaaaga
       61 tgtaacaaaa gcctatctga gatggcattt tgcaaacgaa attcctcact cttttgaacg
      121 ttacttggcg ccatcactac tatacggaat gatgccaatc ttgaaaaaac tttataaaga
      181 tgaagactct ttaaaagcag catataaacg gcagttactg ttcttcaaca ctcaattaag
      241 ctggggtggc ggtgtgatta ctggcctaat gtcttctatg gaacagcaaa gagcagaaga
      301 agagtatgaa gaaaaagaga tcttgatgca ggatgacttg atgtataaca cgaaagcggg
      361 attgatgggg gcactagcag gaatcggaga tgcaatcgat tcaggaaccg tccaatatat
      421 ttttatcgca atcgcggtac cttgggcaca acagggaagt cctttaggcg cactttttcc
      481 ttttatctgc tttgggttgt atcaggtttt actaggggta tttttcgcaa gacaagcttt
      541 cactatgggc cgtaatgcta caggcctaat gcaaaacact ggtgttcaga cagcgattga
      601 aatgctatca gttttagggt tgtttatgat gggggtgctt gcgggaaact atgtaaaagt
      661 agaatcttca ttgaaatttg cgatatccgg acgtgagttt gttatccagg aaattcttga
      721 tcaaatcgtg ccagggatat tacctttagc tgtcgtaatg ggtgtgtact tgttctatac
      781 gaaaaaagga ttgaaagtca cacaagcatt attatggctg actggaatat taattgtgct
      841 agcaggaatc ggtattttat aaaaagaagg gaacgtgaat aagatgggtg tagtcaattt
      901 agcgcgtgtg gatgagcgtt tgatccatgg gcaagtaatg gtaacgttat ctcaaaaaag
      961 tggagtgaat tccatttttg ttgtagacga agttgtagca aaagataaat ttatgagaga
     1021 tctttacaaa aatgcaggaa gccgtacagg acaaaaaaca attgtcatta caccagagaa
     1081 agctaaattc tattgggatg aatatcaatt taaagaatac aattgtattt tgatcgcaaa
     1141 aacagtccaa acgatttacg acttagtaaa acacggaatc cccatggaag aattgaatat
     1201 tggagggatt gctcaaaaaa atcctgatac agatctttta gtgacgaaat ctgtttattt
     1261 aaataaatca gatgctgaaa aattgaaaga aatgaatgaa caatatggcg taaagaatat
     1321 ttattttcaa gccactccat ctgcacctaa aacaggatta aaagatgtat tgaacaagtt
     1381 tgatttgtca taaacaaatg cttagaaaaa agataaagag ggcgaaaaaa tgaagaagaa
     1441 cgagctgttt cgtgattggg aatttcgtta tcgctatatt taccgtaagc gccgtacaaa
     1501 aaagagtaaa cagcgttttc tttcagcatt agtatcagat atttacagta tgagaacaga
     1561 tgtgacagtc attgcttacg atacgctagc ctaccgatca aaaaatattt atgttggaga
     1621 tatcgaaaaa gcagagaaag ttatctgtac ttattacgat acacccgttc atgcattagg
     1681 aagttatttc atgtttgatt ggaaagacca aaggaaaaaa acaatctact ctatattatt
     1741 gtccttcatt ttgttgttca gtttaggttg gtggggaatg atgatatata acaaaaatcc
     1801 tcatcacgta ttcgatctgc tatccgtata aacaggtatc actgtactag catttgggag
     1861 ctactttttc ttattgggaa aagcagctcg cggatggcct agcagacaaa cttttattcg
     1921 aaatacttca tccatattaa cgatgctaga aatgatccgt acgattgatg atccgagtgt
     1981 agcgtatgcg tttgttgatg aaggctgtta tggagaaaag ggcttagaca gcgtgagatc
     2041 gggtatgaaa aaagaggcta ttctttttta tctagactct gttggggcag atacaccgct
     2101 acagttttcg ggaaattatt tttcaaataa agaacagtgg ctgaaacaag ttgataagtt
     2161 gaaagaaaaa aacgtcaatt atatttttag tgcaagaaaa aagcaagcgc agttcttcta
     2221 tttgaccaaa acagatttac gagggaaaac atttaattgg caaaatgcca atcagattat
     2281 tgctcttttt cgataagtaa aaagtgcaaa acaaggagtg agaagactaa tgttggaaat
     2341 catgatcgtt acacatggta agttgagcga aggactgaaa gatgcggcgg aagtaattgt
     2401 cgggacatcg agccatattg aaacaatgtg cttagagtct ggggaggaca tccaaacatt
     2461 cggagagaag gtcaaagaaa aattaactat gatcaacaca gcagaaccca tgctagtatt
     2521 tgttgatcta attagcgcaa gtccgtacaa tcaagcgctc ttggcagtca atgaactgac
     2581 tgaagaaaag aaagcagcca cttatgtcat agggggcgtg aatctgccaa tgttgttaga
     2641 agcaatcaat catcagatgc ttcacacacc gatagaagaa gcggtggaac aaattgtcaa
     2701 acaaggaaaa gataatttaa ctgtttggca tgcttcagcg gaagaaaaaa aattagatga
     2761 ggacgatttt tagaaggaag gctgaaaaga tgaagtgggg atttagatgg tatggtgaaa
     2821 aaggggattc gatcccatta aaatatgttc gccaaatacc gggaataaat gggataattg
     2881 gaactttgct gactaaaatg cctggagatg tttgggagat ttcagaaatt gaggagttga
     2941 aagcatctgt tgagagccaa ggactggaac tgcttggaat tgaaagtgta gcgatccacg
     3001 atgcaatcaa ggcagggaca gatgaacgag attactatat tgataactat atacgaacaa
     3061 tcaaaaactt gtctcgatgt ggggttcgat tgatttgtta tagcttcaaa ccaatttttg
     3121 gatgggcgaa aactgatttg tttaatgaaa acaacgatgg aagctattct cttttatacg
     3181 atcagaaaat cgtcgatcag atggagccag gagaaatgta tcaattgata cacagccagt
     3241 caaagggatt caaattgccg ggttgggaag aagaacggtt gaaaaaattc gctcagctgg
     3301 aaaaactgta tgaaggaatg accgaagaag aattatttga aaatctgact tattttttag
     3361 aaaaagtgat tccagtgtgc gaaaaagcag atgtaaaaat ggctatccat ccagatgatc
     3421 cgccatggga actttttggt tttcctagag tgacgaaaaa tcttggcgac ttgaagaaaa
     3481 ttctaaatgc agtagattct ccatataatg gactaacgct gtgcacagga tctttagggg
     3541 caaatccgga aaacgattta gttgaaatca tccatgaggt aggttcgcgc atccattttg
     3601 tccacttcag aaacgtggag tttttaggag aaagaaagtt caaagaaacg gcacatccct
     3661 ctacagaagg ctcccttgat atgtatcata ttatgaaagc gttggtgcaa gaagggttcg
     3721 acggtcctat acgccctgat catggtagaa ccgtgtgggg tgaagtggct atgcctggat
     3781 atggcctgta tgatcgtgca atgggactca cttacatgca aggtctatat gaggcgataa
     3841 gtaaggaaaa accactggga gagcattatg aataaaatca agctcttcat ctttgatatg
     3901 gatggccttt tattagaaac tggacgttta gcttatcgtg cttatgtaaa atcagcacaa
     3961 aagtatgatt atgaaatgcg taaggaagtc tattatttac taactggcca aacagaaatg
     4021 gcgataagag aacaaatggg cattttgtac ggagaagatg ttccatatat caaatggcga
     4081 gaagcaatca atcaatataa agaaaaaatc gtgaaagaag ataagagagt atatacgaaa
     4141 aaaggagcag aagaaatttt atcttttgca aaagaaagag gaatccatac aatcgtggct
     4201 tcgtctaata cacgggtaaa agtagaaatg tatttaaaaa tggaaaatct atatgccttg
     4261 tttgatcaaa tcatttcagg ggatgatgta aaaaaaggaa agccggaacc agagatcttt
     4321 ttgaaagctt gttcaaaaat gaatattcct ccaagtgaag cacttgtatt tgaagactcg
     4381 attgcaggga tcgaagcagc aaggcgagcg ggcattttgt cttttctcat caaagatcat
     4441 ttgatagggt tgcccgatca taatgggaag cataagttga aagtagatgt aagtttatat
     4501 gaatccaata aagcagacta tgaattttat gacctgcatc aagcaaaacg atttttagaa
     4561 agtaaagggt tgtatctcta ataaagagga ctattttcta gtcctcttta tttattgtcc
     4621 tgcacgactg agggaacaga tgaaaaagaa gtaatttttt attttgaagt atctacctta
     4681 tttgtagtga acaatttaga acaaacacaa aacgcatcta ctgttatcta ccagtagatg
     4741 cgtttaaaga gaagaacgag aatcgtccat atgagggttt ccactcctta tgcagatttt
     4801 tttaattctt gcactgcttg ttcgatcgta acacctgtcg ctacatgatt ggtattttct
     4861 ttgtcaaaaa cgacaaatag attcaaatct gtatccaagg ttactcgata ttgtatatct
     4921 ttgttataga atgtcatagc cattctcctt tctttaaata cttgctgaaa ggcaacgaac
     4981 gcgttgataa cgaaattcca tttataagta taccaccaat tgaaaggttt tcatagttaa
     5041 gaaattttaa agtcaaaagt tgcagataaa agcaaataaa caagaaaaca aaaagtgaat
     5101 caatcgcggt tattcaactt tttcttcgat tcgaagacaa tagaagacaa tgaattttat
     5161 atttcattgc attatccttg tgttattaga aaaagcatga tatattaaat gagtaatcta
     5221 ttttgaaacg taatttgagc gatatatcta catagataaa actccttttg cctatcaaat
     5281 atttattgca acgaaaaaac gtacattgat acgtatcagg aggaatttat ttatgaataa
     5341 cggtacagta aaatggttca acgcagacaa aggttttggc tttatcactg gtgaagatgg
     5401 aaatgatgta tttgcacatt tttcagctat ccaaggtgac ggcttcaaaa ctttagaaga
     5461 aggccaagca gtgtcttacg atgttgaaga tggtcaacgt ggccctcaag caacaaacat
     5521 tgttaaagct taataaaaat tgacttttaa ccgtcttttc gaaagaaaag acggtttttt
     5581 tgtacgaaaa aattcattgg tcgttgaatg ggctgaatag tagtgtataa aacaattttg
     5641 tggagcgtga agcttttatg gtagaggaaa atacgaataa agtgatgttg ataaaaagat
     5701 tcctatcttg aatatgaatc gagatgtctt gaaaatgaat gagtttgacc aatcattatc
     5761 ctatcgaaat ttacagtttc gttcgattgg tctgtcaatt aatgaaaaag taaaaaagaa
     5821 tatgttctag gaagagggcg gcacatctaa atttttaagt aacggacagt tcaaatatca
     5881 agcattgaaa gaggctatcc tactgtttga aggaatacga atatataaaa acgacaaaga
     5941 ggaaaaagta gttcattaaa tcccttcaag tga
//
LOCUS       DACDLM010000117         5740 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.119, whole genome shotgun sequence.
ACCESSION   DACDLM010000117 DACDLM010000000
VERSION     DACDLM010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5740
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.119"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..433
                     /locus_tag="IV356_002730"
     CDS             <1..433
                     /locus_tag="IV356_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HAP9016350.1"
                     /translation="KDYWGESKGFIYPDSNMGGNWKATNPKKEQEAMKLKNTKSNNLL
                     YATCKHFRHVRDTEFTSYHLSGIVIDSFVYEAMGNWKFVENNSGGQNISSVSYETALL
                     EYYNSHKVMGGLNLYSPGSNQFVNSDSSIICLEKVLKKIAL"
     gene            453..1013
                     /locus_tag="IV356_002731"
     CDS             453..1013
                     /locus_tag="IV356_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLATT domain-containing protein"
                     /protein_id="HAP9016351.1"
                     /translation="MGDEKKRLEVQLREAYGRVTYTYTTHLKQADNIISDNKILRCLQ
                     IGLSALTTGGILSTIITDNSELTFVAGLCSTISLGLNLYFKNFDLAEEAKNHQIVADE
                     LWLIREEYVSLLTDLNRLSVEDIVKKRDQLMNETHEAYKNAPKTNSKSYESAQKALKS
                     EEEQFFTEEELDKMLPEHLRKKSSKY"
     gene            1837..2604
                     /locus_tag="IV356_002732"
     CDS             1837..2604
                     /locus_tag="IV356_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HAP9016352.1"
                     /translation="MRDRILEVNQEMVNKLTNISGNYEKYDGTLLDNYIFHDTQNIRI
                     GRSKPRAFILIREKYLNEWNSTYEMVMTDNFEKVLDFRNALLGSDMGNSSLESIEVEN
                     KTENEGEGLIKNVLKIEQKYISEDRSFYRVTSSVGLANFATNLIGNNASESLLVMCLN
                     TKNEVIAYSEVFKGGINQSVAIPREIFQLALLNNSAKIAVSHNHPSGYEFPSENDKSF
                     TTNLKNAGKTIGIELLDHIIVTSKNTSYYSFQENGSL"
     gene            2630..3172
                     /locus_tag="IV356_002733"
     CDS             2630..3172
                     /locus_tag="IV356_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016353.1"
                     /translation="MGERTQALITVKYGNSKTKASVSIHYQWGYGRYMLMDVLNQGIY
                     LINKAYDLRDKSREELAKGIFDRSTGVINFATYESGMSAYDETGFDGRYEPYQETIED
                     VMKFSDNNDGYAHLEMVFDENGYSLDDKTRLRLFDIEGKQIGLNKFCKNGKEFATKDF
                     IKGYRLLLENYGINLEESVK"
     gene            3173..3739
                     /locus_tag="IV356_002734"
     CDS             3173..3739
                     /locus_tag="IV356_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016354.1"
                     /translation="MFQKRKDKFPNLEVKSQKVIDGEMIELFQKNYGTIETTASCKYY
                     FQGKRNTFKGFADSDEELAKKIIDWLVSSEHVAREDTVRTTINGEVLTGTRCVCCNHE
                     FVEDEGCYRINEYGDFICQSCHEIEFPTERSWFEYMLQDYEMEKENGEVVFCTKEELS
                     KRSDDEIEDWCVWLVGADDCVAYYTTAE"
     gene            3754..4002
                     /locus_tag="IV356_002735"
     CDS             3754..4002
                     /locus_tag="IV356_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016355.1"
                     /translation="MEGMDFLDHEDLVDFGYTWKGMVGISRSLANAFYERNYAVYVLY
                     DDDTENLVDEEYKLDLENVLYGIEKEDLAKYIFSWLGQ"
     gene            4022..4261
                     /locus_tag="IV356_002736"
     CDS             4022..4261
                     /locus_tag="IV356_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016356.1"
                     /translation="MTKFKSKGMQWCSYYYVGNDEDLLRKTQRKGYPDKILKQIGYYM
                     PEERIEKEFCEVLFDSEQLLVLLTQNKLICQFENN"
     gene            4632..4913
                     /locus_tag="IV356_002737"
     CDS             4632..4913
                     /locus_tag="IV356_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HAP9016357.1"
                     /translation="MKVKNPTEKSRIQVGIDKNLKENAEMILEELGLNPTTAITILYK
                     QVVARGEFPVEIKLSEEEKQGIRLQQLTKDMPVDVLDTDEKLEEWFDEA"
     gene            4903..5244
                     /locus_tag="IV356_002738"
     CDS             4903..5244
                     /locus_tag="IV356_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAP9016358.1"
                     /translation="MKPNEIVTVYVAFTDKNGGKRRPILVVSDKEDRVEFFGITSQYE
                     KKSDQIKRVYFPIGEWEKAGLKKQSWIDVGSLKAIPKSRENISFKKVGMLSASDTKKL
                     NKFIERLQRKV"
BASE COUNT         2168 a          764 c         1158 g         1650 t
ORIGIN      
        1 aaaagattat tggggtgagt caaaagggtt tatttatcca gattcaaaca tgggagggaa
       61 ctggaaagct acaaatccca aaaaagagca agaagccatg aaattaaaga atacaaaaag
      121 taataattta ttatatgcta cgtgtaaaca ttttcgacat gtacgagata cagaatttac
      181 gagttatcat ctttcaggaa tagtaattga cagtttcgta tatgaggcta tgggaaattg
      241 gaaatttgtt gaaaataaca gtgggggtca aaacattagt tctgtatctt atgagacagc
      301 tttattagaa tactataact cacataaagt tatgggcggt ttaaatttat actctcctgg
      361 aagcaatcaa tttgttaatt ctgatagtag tatcatatgt ttagaaaaag tattaaaaaa
      421 aatagcttta taaagtttta tggaggaaca acatgggaga cgaaaaaaag cgcttggaag
      481 ttcaattacg tgaagcatat ggacgagtaa cgtatactta caccactcat ttaaagcaag
      541 ccgataatat tatttctgac aataaaattt taaggtgtct tcaaattggt ttgtcagccc
      601 ttactactgg agggatactt agtaccatta ttactgataa tagtgagtta acctttgttg
      661 ctggattatg ttcaacaatt tctcttggat taaacttata ctttaagaac tttgatcttg
      721 ctgaagaagc taaaaatcat caaattgttg ccgatgaatt atggttgatc agagaagaat
      781 acgtaagctt actaacagat ttaaatcgtt taagtgttga agatattgtg aaaaaaagag
      841 atcaattaat gaacgaaact catgaagcat ataaaaatgc ccctaaaaca aatagtaaaa
      901 gctatgaatc agctcagaaa gcattaaaat ctgaagaaga gcaatttttt acagaagagg
      961 aattggataa gatgttacca gagcatctta gaaaaaagag ttctaaatat tgaactcttt
     1021 ttttatgctt aaaattctct tgtaattttt ctattcaatc aataaataat ctatatttaa
     1081 gaagaaatat gatgatagaa acatctccta aagccaccgc aagccgttct aagcatagct
     1141 tagcccgaca ttgctagata tgctcatctc accatgaacg tttcctaaag ccaccgcaag
     1201 ccgtcctagt cattgcctag tccgacatcg ctagattagt gcatctcgcc ataaaagttt
     1261 tctaaagcca ccgcaaaccg tcctagccat cgcctagtcc gattttgctt gatcggttcc
     1321 atttctgttt atttagtggg tcaacaccgt aatcttaaat agccatcgcc tatttaagat
     1381 tactaggtct gctttgaagg taaaaagtct ttcattcttc aagactttta ggctttcaag
     1441 ctacgcctga aagcattgaa attcatcgct ctttatttgg ttttgccatt tataattcct
     1501 tacgcccatt atctttttcg cctgtcttgc cttgtcagaa gtgtttagag cttatctcat
     1561 ctttggatta atacaagtgg cgtaaatttt tttctaaacg caagcgttac gaaaataatt
     1621 tacttaaaca cttgtattaa tccggcagat aagaacgcat tctaatcact cccgacaagg
     1681 caagacaggc gaaaaagata aataaatgaa cgaaaggaag aaacataaaa tgcaaaacca
     1741 aatagctatg aagaaaaaaa cacctccctc taaaacaatc caaacaaaaa agaattttga
     1801 aaaaccaaaa atcaaaaaca gaaagaagcg ttcaacatga gagatagaat tttagaagtt
     1861 aatcaagaaa tggtaaacaa gttaacaaat atcagtggga actatgaaaa gtacgatggt
     1921 actttacttg ataactatat ttttcacgat acacaaaata tcagaattgg cagaagtaaa
     1981 ccgagagcgt tcattctcat cagagaaaaa tatttgaatg aatggaatag cacctatgaa
     2041 atggttatga ctgataactt tgaaaaggta ttggatttca gaaatgcttt gttgggttct
     2101 gatatgggaa atagcagtct tgaatctatt gaagttgaaa acaagaccga gaatgaaggt
     2161 gaaggattga ttaagaatgt cttgaaaatc gaacaaaaat atatcagtga agatagaagt
     2221 ttttatagag tcacaagctc ggttggtcta gcaaactttg ctactaactt aattggaaac
     2281 aatgctagtg aatctttgct agtgatgtgt ctgaatacaa agaatgaggt cattgcttat
     2341 agcgaagttt tcaaaggtgg aattaatcaa tcagtagcga taccaagaga gatttttcaa
     2401 ctagctttgc taaacaattc agcaaaaatc gcagtatcac ataatcatcc gagcggatat
     2461 gaatttccaa gtgaaaatga caaaagtttt actacgaatt tgaaaaacgc aggaaaaaca
     2521 attggtattg aattgttaga ccatatcatc gtaacaagta aaaacacaag ctattactca
     2581 tttcaagaaa atggttcttt ataaaaatta gagaaaagag gaaaacaaga tgggcgaaag
     2641 aacacaagcg ttaattacag tcaaatatgg taacagcaaa acgaaagcaa gcgtgtcgat
     2701 tcattatcag tgggggtatg gtcgatatat gctgatggac gtattgaatc aaggaattta
     2761 tttaatcaat aaagcatacg acttacgaga taaatcaaga gaagaattag caaaaggaat
     2821 ctttgataga agtacagggg ttatcaattt tgccacctat gaatcaggta tgagtgctta
     2881 tgatgaaaca ggatttgatg ggcgctatga accttatcaa gaaacgattg aagatgtgat
     2941 gaagttttct gataacaatg atggctatgc tcatttagag atggtgttcg atgaaaatgg
     3001 atatagtcta gatgataaaa ccagattgcg attgtttgat attgagggta aacagatagg
     3061 actaaacaag ttttgtaaga atggaaaaga gtttgctaca aaagatttta ttaagggata
     3121 cagattgttg ctagaaaatt atggaataaa cctagaagag agcgtgaaat aaatgtttca
     3181 aaaaagaaaa gacaaattcc ctaatttaga agtgaaaagt caaaaagtga ttgatggtga
     3241 aatgattgaa ctattccaaa aaaattatgg aacgatagaa actaccgcaa gttgcaaata
     3301 ctactttcaa ggaaagagaa acacgtttaa aggctttgcc gattctgatg aagaattggc
     3361 aaagaaaatc attgattggc ttgtcagcag tgaacacgta gcaagagaag ataccgttag
     3421 aacaacgatt aatggggaag tcctaacagg tactagatgt gtttgttgta atcatgaatt
     3481 tgtagaagat gaaggttgct accgaatcaa tgaatatggt gattttattt gccagagttg
     3541 ccacgagata gaatttccaa ccgaaagaag ttggtttgaa tacatgctac aagattatga
     3601 gatggaaaaa gaaaatggtg aagtagtttt ttgtaccaaa gaggaattga gtaagagaag
     3661 cgatgatgaa attgaagatt ggtgtgtgtg gttagtaggg gcagatgatt gcgttgcata
     3721 ttacacaaca gcagaatagg agtgtgaatc agcatggaag gaatggattt tctagatcat
     3781 gaagatttgg ttgattttgg ttatacatgg aaaggaatgg taggtattag cagaagtctt
     3841 gctaatgcct tttacgaaag aaattatgca gtatatgttc tttatgatga cgatacagaa
     3901 aaccttgttg acgaggaata taaattggat ttagagaatg ttttatatgg aatagaaaag
     3961 gaagatttag caaaatatat tttttcatgg ttgggtcaat aagtgaaagg aagatagaaa
     4021 catgacaaaa tttaaaagta agggtatgca atggtgttct tattattatg ttggaaatga
     4081 tgaagattta ttgagaaaaa cccaacgaaa aggttatcca gataagatat tgaaacaaat
     4141 aggttattac atgccagaag agaggataga aaaagaattt tgtgaggttc tttttgatag
     4201 tgaacagcta ttagttttgt taacccaaaa taaattgatt tgccaatttg aaaataatta
     4261 agatgaggtg gtgaaccatg aatgaagata agatggtatt aagtgaatat gctagattga
     4321 gaactattaa ttctttagca tctcatttaa gttgttcttt ccttacaaag gtgctaaaat
     4381 taatttacaa atgtgaagat tttgtacaag agaagcacaa agacaagcct actgcgaata
     4441 ggcttgtctt tttttcattc attacgattc cgtatgtgtg ggttagcgac aatttgttca
     4501 attaccgtat gatatagcat cttaatttga ttagattact tgcaatgtag tttattaaga
     4561 gtataatata atcataaatg tggataattt gagaaataat gagtgtttta tactcaaaag
     4621 gagtggatga aatgaaggtc aaaaatccaa ctgaaaaaag cagaatccaa gtcggaatag
     4681 acaagaattt aaaagagaac gcagaaatga tattggaaga gctaggttta aatcctacaa
     4741 cagcaataac aattctttac aaacaagtag tcgctagagg tgagtttcca gtagagataa
     4801 agctaagtga agaggagaag caaggaatca gattgcaaca gctaactaag gacatgccag
     4861 tagatgttct agatacagat gaaaagttag aagagtggtt cgatgaagcc taatgagata
     4921 gtaacggtct atgttgcatt tacagataaa aatggtggta aaagaagacc tattttggtg
     4981 gttagtgata aagaagatag agtagaattt tttggaatca caagtcaata tgagaagaaa
     5041 tcagaccaaa taaagagagt gtattttcct attggagaat gggaaaaagc aggtcttaaa
     5101 aagcaatcat ggattgacgt agggtcttta aaggctattc ccaaaagccg agagaacata
     5161 tcatttaaaa aggttggtat gctatcagct agtgatacga aaaagctaaa taagtttatc
     5221 gagagattac aaagaaaagt ctaacaaggc ttttcttttt ttgcttatat gtatattaag
     5281 atatacgtct atacaaacgt atttatgtat ataaaaatac acgtaaatat atacgtgaat
     5341 ataaacatta agaaaatatt aagaatgatt aaatagtggt aattgttaat atacgaatta
     5401 taagatatat tttaaatcga atgtatgtaa ataaataaaa tgactggagg atatttaata
     5461 gtgataaata acagtaatcc agacggatac agtgagtgaa gtagcttgct acgaacgaac
     5521 aagcagaatg aaacggtagt ttcattagag caagtcgctt gcgacgtagc gttaccgctg
     5581 atgtaactgg caagttacat agagagagtt tgcttgcaaa cgaacgttac ctacttgaat
     5641 agaaaacaaa aataacagat tagtgaattt taaataggag ccacaactca accaaccgct
     5701 tgcggtgggt gagtcccacg gaggaaaaga cgaacgaacg
//
LOCUS       DACDLM010000118         5732 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.120, whole genome shotgun sequence.
ACCESSION   DACDLM010000118 DACDLM010000000
VERSION     DACDLM010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.120"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            133..1287
                     /locus_tag="IV356_002739"
     CDS             133..1287
                     /locus_tag="IV356_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAP9016359.1"
                     /translation="MEYSEERQRLAYVRLYGGILHLRDSVRISEKEKIKITEMYTSIN
                     GELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQ
                     REMLLDALLEISDSDPLLQYYVDSTTHEIILSFLGKVQMEVISALLQEKYHVEIELKE
                     PTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSF
                     QNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKA
                     GTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIVDTQLKNNEVILSGEIPARCIQEY
                     RSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT"
     gene            1385..2758
                     /gene="tet(L)"
                     /locus_tag="IV356_002740"
     CDS             1385..2758
                     /gene="tet(L)"
                     /locus_tag="IV356_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HAP9016360.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
     gene            3322..4584
                     /locus_tag="IV356_002741"
     CDS             3322..4584
                     /locus_tag="IV356_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Plasmid recombination enzyme type 2"
                     /protein_id="HAP9016361.1"
                     /translation="MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENY
                     DLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRF
                     FEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQ
                     DKFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYS
                     DKVKSDLEVPAKRHMKSVEVPTGEKSMFGLGKEIMKTEKKPTKNVVISERDYKNLVTA
                     ARDNDRLKQHVRNLMSTDMAREYKKLSKEHGQVKEKYSGLVERFNENVNDYNELLEEN
                     KSLKSKISDLKRDVSLIYESTKEFLKERTDGLKAFKNVFKGFVDKVKDKTAQFQEKHD
                     LEPKKNEFELTHNREVKKERSRDQGMSL"
     gene            4829..5716
                     /locus_tag="IV356_002742"
     CDS             4829..5716
                     /locus_tag="IV356_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002499206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HAP9016362.1"
                     /translation="MCPNSSIYSDEKSRVLVDKTKSGKVRPWREKKIANVDYFELLHI
                     LEFKKAERVKDCAEILEYKQNRETGERKLYRVWFCKSRLCPMCNWRRAMKHGIQSQKV
                     VAEVIKQKPTVRWLFLTLTVKNVYDGEELNKSLSDMAQRFRRMMQYKKINKNLVGFMR
                     ATEVTINNKDNSYNQHMHVLVCVEPTYFKNTENYVNQKQWIQFWKKAMKLDYDPNVKV
                     QMIRPKNKYKSDIQSAIDETAKYPVKDTDFMTDDEEKNLKRLSDLEEGLHRKRLISYG
                     GLLKEIHKKWFCCKVLNKE"
BASE COUNT         1973 a          812 c         1175 g         1772 t
ORIGIN      
        1 tccttgtacc ctgtttatca tggaagcgca aaaagcaaca tagggattga gcagcttata
       61 gaagtgataa cgaataaatt ttattcatca acatacagaa agaagtctga actttgcgga
      121 aatgtcttca aaattgaata ttcggaagaa agacaacgtc ttgcatatgt acgcctttat
      181 ggcggaatcc tgcatttgcg ggattcggtt agaatatcgg aaaaggaaaa aataaaaatt
      241 acagaaatgt atacttcaat aaatggtgaa ttatgtaaaa ttgataaggc ttattccggg
      301 gaaattgtta ttttgcaaaa tgagtttttg aagctaaata gtgttcttgg agatacaaag
      361 ctattgccac agagagagag aattgaaaat ccgctccctc tgctgcaaac aactgttgaa
      421 ccgagcaaac ctcaacaaag ggaaatgtta cttgatgcac ttttagaaat ctccgacagt
      481 gacccgcttc tacaatatta tgtggattct acgacacatg aaattatact ttctttctta
      541 gggaaagtac aaatggaagt gattagtgca ctgttgcaag aaaagtatca tgtggagata
      601 gaactaaaag agcctacagt catttatatg gagagaccgt taaaaaatgc agaatatacc
      661 attcacatcg aagtgccgcc aaatcctttc tgggcttcca ttggtttatc tgtatcaccg
      721 cttccgttgg gaagtggaat gcagtatgag agctcggttt ctcttggata cttaaatcaa
      781 tcatttcaaa atgcagttat ggaagggata cgctatggtt gcgaacaagg attatatggt
      841 tggaatgtga cggattgtaa aatctgtttt aagtatggct tatactatag ccctgttagt
      901 accccagcag attttcggat gcttgctcct attgtattgg aacaagtctt aaaaaaagct
      961 ggaacagaat tgttagagcc atatcttagt tttaaaattt atgcgccaca ggaatatctt
     1021 tcacgagcat acaacgatgc tcctaaatat tgtgcgaaca tcgtagacac tcaattgaaa
     1081 aataatgagg tcattcttag tggagaaatc cctgctcggt gtattcaaga atatcgtagt
     1141 gatttaactt tctttacaaa tggacgtagt gtttgtttaa cagagttaaa agggtaccat
     1201 gttactaccg gtgaacctgt ttgccagccc cgtcgtccaa atagtcggat agataaagta
     1261 cgatatatgt tcaataaaat aacttagtgt attttatgtt gttatataaa tatggtttct
     1321 tgttaaataa gatgaaatat tttttaataa agatttgaat taaagtgtaa aggaggaatt
     1381 aattatgaag tgtaatgaat gtaacagggt taaatacaac caaattttaa tttggctttg
     1441 cgttttatct ttttttagcg tattaaatga aatggttttg aacgtctcat tacctgatat
     1501 tgcaaatgat tttaataaac cacctgcgag tacaaactgg gtgaacacag cctttatgtt
     1561 aaccttttcc attggaacag ctgtatatgg aaagctatct gatcaattag gcatcaaaag
     1621 gttactccta tttggaatta taataaattg tttcgggtcg gtaattgggt ttgttggcca
     1681 ttctttcttt tccttactta ttatggctcg ttttattcaa ggggctggtg cagctgcatt
     1741 tccagcactc gtaatggttg tagttgcgcg ctatattcca aaggaaaata ggggtaaagc
     1801 atttggtctt attggatcga tagtagccat gggagaagga gtcggtccag cgattggtgg
     1861 aatgatagcc cattatattc attggtccta tcttctactc attcctatga taacaattat
     1921 cactgttccg tttcttatga aattattaaa gaaagaagta aggataaaag gtcattttga
     1981 tatcaaagga attatactaa tgtctgtagg cattgtattt tttatgttgt ttacaacatc
     2041 atatagcatt tcttttctta tcgttagcgt gctgtcattc ctgatatttg taaaacatat
     2101 caggaaagta acagatcctt ttgttgatcc cggattaggg aaaaatatac cttttatgat
     2161 tggagttctt tgtgggggaa ttatatttgg aacagtagca gggtttgtct ctatggttcc
     2221 ttatatgatg aaagatgttc accagctaag tactgccgaa atcggaagtg taattatttt
     2281 ccctggaaca atgagtgtca ttattttcgg ctacattggt gggatacttg ttgatagaag
     2341 aggtccttta tacgtgttaa acatcggagt tacatttctt tctgttagct ttttaactgc
     2401 ttcctttctt ttagaaacaa catcatggtt catgacaatt ataatcgtat ttgttttagg
     2461 tgggctttcg ttcaccaaaa cagttatatc aacaattgtt tcaagtagct tgaaacagca
     2521 ggaagctggt gctggaatga gtttgcttaa ctttaccagc tttttatcag agggaacagg
     2581 tattgcaatt gtaggtggtt tattatccat acccttactt gatcaaaggt tgttacctat
     2641 ggaagttgat cagtcaactt atctgtatag taatttgtta ttactttttt caggaatcat
     2701 tgtcattagt tggctggtta ccttgaatgt atataaacat tctcaaaggg atttctaaat
     2761 cgttaaggga tcaactttgg gagagagttc aaaattgatc ctttttttat aacaggaatt
     2821 caaatctttt tgttccatta aagggcgcga ttgctgaata aaagatacga gagacctctc
     2881 ttgtatcttt tttattttga gtggttttgt ccgttacact agaaaaccga aagacaataa
     2941 aaattttatt cttgctgagt ctggctttcg gtaagctaga caaaacggac aaaataaaaa
     3001 ttggcaaggg tttaaaggtg gagatttttt gagtgatctt ctcaaaaaat actacctgtc
     3061 ccttgctgat ttttaaacga gcacgagagc aaaacccccc tttgctgagg tggcagaggg
     3121 caggtttttt tgtttctttt ttctcgtaaa aaaaagaaag gtcttaaagg ttttatggtt
     3181 ttggtcggca ctgccgacag cctcgcagag cacacacttt atgaatataa agtatagtgt
     3241 gttatacttt acttggaagt ggttgccgga aagagcgaaa atgcctcaca tttgtgccac
     3301 ctaaaaagga gcgatttaca tatgagttat gcagtttgta gaatgcaaaa agtgaaatca
     3361 gctggactaa aaggcatgca atttcataat caaagagagc gaaaaagtag aacgaatgat
     3421 gatattgacc atgagcgaac acgtgaaaat tatgatttga aaaatgataa aaatattgat
     3481 tacaacgaac gtgtcaaaga aattattgaa tcacaaaaaa caggtacaag aaaaacgagg
     3541 aaagatgctg ttcttgtaaa tgagttgcta gtaacatctg accgagattt ttttgagcaa
     3601 ctggatccag gagaacaaaa acgatttttt gaggaaagtt ataaattatt ttccgaacga
     3661 tatggcaagc aaaatattgc ttatgcaaca gttcataatg atgagcaaac ccctcacatg
     3721 catttaggtg ttgtgcctat gcgtgatgga aaactgcaag gaaaaaatgt gtttaatcgt
     3781 caagaactgt tatggctaca agataaattc cccgagcata tgaaaaaaca gggttttgag
     3841 ttgaagcgtg gtgaacgtgg ctctgaccgt aaacatattg agacagctaa atttaaaaaa
     3901 caaactttgg aaaaagagat tgattttcta gaaaaaaatt tagcagttaa aaaagatgaa
     3961 tggactgctt atagcgataa agttaaatca gatttagaag taccagcgaa acgacacatg
     4021 aaaagtgttg aagtgccaac gggtgaaaag tccatgtttg gtttgggaaa agaaataatg
     4081 aaaacagaaa agaaaccaac caaaaatgtt gttatatcgg agcgtgatta taaaaactta
     4141 gtgactgctg cgagagataa cgataggtta aaacagcatg ttagaaatct catgagtact
     4201 gatatggcga gagaatataa aaaattaagt aaagaacatg ggcaagttaa agaaaaatat
     4261 agtggtcttg tagagcgatt taatgaaaat gtaaatgatt ataatgagtt gcttgaagaa
     4321 aacaagtctt taaagtctaa aataagcgat ttaaagcgtg atgtgagttt aatctatgaa
     4381 agcactaagg aattccttaa ggaacgtaca gacggcttaa aagcctttaa aaacgttttt
     4441 aaggggtttg tagacaaggt aaaggataaa acagcacaat tccaagaaaa acacgattta
     4501 gaacctaaaa agaacgaatt tgaactaact cataaccgag aggtaaaaaa agaacgaagt
     4561 cgagatcagg gaatgagttt ataaaataaa aaaagcacct gaaaaggtgt ctttttttga
     4621 tggttttgaa cttgttcttt cttatcttga tatatataga aataacgtca tttttatttt
     4681 agttgctgaa aggtgcgttg aagtgttggt atgtatgtgt tttaaagtat tgaaaaccct
     4741 taaaattggt tgcacagaaa aaccccatct gttaaagtta taagtgacca aacaaataac
     4801 taaatagatg ggggtttctt ttaatattat gtgtcctaat agtagcattt attcagatga
     4861 aaaatcaagg gttttagtgg acaagacaaa aagtggaaaa gtgagaccat ggagagaaaa
     4921 gaaaatcgct aatgttgatt actttgaact tctgcatatt cttgaattta aaaaggctga
     4981 aagagtaaaa gattgtgctg aaatattaga gtataaacaa aatcgtgaaa caggcgaaag
     5041 aaagttgtat cgagtgtggt tttgtaaatc caggctttgt ccaatgtgca actggaggag
     5101 agcaatgaaa catggcattc agtcacaaaa ggttgttgct gaagttatta aacaaaagcc
     5161 aacagttcgt tggttgtttc tcacattaac agttaaaaat gtttatgatg gcgaagaatt
     5221 aaataagagt ttgtcagata tggctcaaag atttcgccga atgatgcaat ataaaaaaat
     5281 taataaaaat cttgttggtt ttatgcgtgc aacggaagtg acaataaata ataaagataa
     5341 ttcttataat cagcacatgc atgtattggt atgtgtggaa ccaacttatt ttaagaatac
     5401 agaaaactac gtgaatcaaa aacaatggat tcaattttgg aaaaaggcaa tgaaattaga
     5461 ctatgatcca aatgtaaaag ttcaaatgat tcgaccgaaa aataaatata aatcggatat
     5521 acaatcggca attgacgaaa ctgcaaaata tcctgtaaag gatacggatt ttatgaccga
     5581 tgatgaagaa aagaatttga aacgtttgtc tgatttggag gaaggtttac accgtaaaag
     5641 gttaatctcc tatggtggtt tgttaaaaga aatacataaa aaatggttct gttgcaaagt
     5701 tttaaataaa gaataaaatc ccttacggta tc
//
LOCUS       DACDLM010000119         5689 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.121, whole genome shotgun sequence.
ACCESSION   DACDLM010000119 DACDLM010000000
VERSION     DACDLM010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5689
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.121"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(488..1297)
                     /locus_tag="IV356_002743"
     CDS             complement(488..1297)
                     /locus_tag="IV356_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP9016363.1"
                     /translation="MVKESVIGKKELRSIFWRSFFMQSSWSFDKMMAYGQMNGIERSL
                     RKIYPNDDDYYTALQRHTETFNITPHIAPFVMSLSVTMEEENAKNPEFDTDAINKIKT
                     GLMGPLSGIGDSFFWGTFRVIAAGIGISFAQQGNILGMILYFTLYTAIHFIFKWLATK
                     YGYVLGTKFIDDTEDNHMIDKLSHGASILGLTVIGAMIGTMVTLNTSLKFTVGGAETS
                     LQSIFDQIFPGLLPLGITFLCVWLYSKGHKTITIILGIFVLCFLGTLGGIF"
     gene            complement(1297..2043)
                     /locus_tag="IV356_002744"
     CDS             complement(1297..2043)
                     /locus_tag="IV356_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP9016364.1"
                     /translation="MIQAILIALVAFLASIDEYTFGASMMGRPLFTAPFVGLILGDLE
                     SGIIIGATLESMFMGSIMVGSATPPEVYASSVLGTAIAIQSGQGVGTAVALTLPLSIF
                     LQMWRNFAYAMPITYFNNKMDEALVNHDFKKAQKYHYVAQPLIVGVPSAILVFVATYF
                     GVSTINAMIKLIPQVVLDSFDVAAGVLSCVGLALLIKMMANKAMMPYLFLGFVGVMYL
                     KMDVVGVAVVGLCLALLAVQKLTFEEEEDL"
     gene            complement(2061..2528)
                     /locus_tag="IV356_002745"
     CDS             complement(2061..2528)
                     /locus_tag="IV356_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP9016365.1"
                     /translation="MIKLLRVDERFVHGQVAFAWTNNLGANCIFVASNEIATNNLRKK
                     TLKMAVPTGTKFVVKDMTEAISVLNGEKIKKYQVFLIVGTVEDAYEITQHVPEIKEVN
                     LGNLKKNENRKMITSSVYLNEQELDLVKKMTENGITVQCQAVPTDKKINPLHD"
     gene            complement(2528..2938)
                     /locus_tag="IV356_002746"
     CDS             complement(2528..2938)
                     /locus_tag="IV356_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAP9016366.1"
                     /translation="MRKIVIATHSMMAKGLKDTLEFIIGPQKSLLAITAYIDSDYSIN
                     QEIEQLFSDLAPDDELIVTVDLLGGSVSNAFSEQIGKDNFYLISGVNLPLLLELCLSG
                     EQDTKKLIQKAMNSGNEGIVLVNELLEKTEEDDF"
     gene            complement(2949..3962)
                     /locus_tag="IV356_002747"
     CDS             complement(2949..3962)
                     /locus_tag="IV356_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009141002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP9016367.1"
                     /translation="MLGFSEERFLSVLNGAVKNIETINQVADAISEKGFKNLYLVGSG
                     GTYATISPLAYLLSTHSELDYYHEIAAEVVCSQPKKINKDTVLITSSLTGTTQETVDV
                     VKYANSQGATTIAFVGNAATPLGEIVDYAIENDADNDTLVEELQLQFFALGARLMKNN
                     GEFPEYDEFIQTLQKMPEVLLSVRQQNDQKALEFAEKHKNTEFHMFVGAGNTYGAAYE
                     YAMCVLEEMQWIATKSIHAAEFFHGTIEMTDKSMSFVLLKGEDQTRPLVDRVERFVNK
                     YSDVVTVFDTADFELAGVPSAMRQYVAPMVMATALERVSAHFEKVRDHSLDIRRYYRT
                     VEY"
     gene            4179..4913
                     /locus_tag="IV356_002748"
     CDS             4179..4913
                     /locus_tag="IV356_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP9016368.1"
                     /translation="MNTEELTNKLIQDIEQEKYKYAQAIPSERDFVQIYEMNRSAVKK
                     AIQQLVNKEYLLKIHGKGTFVKKNIHEHLQIKFHGLSELLEREGIQPSSLILASEIKP
                     AGHIVGKALQLEPTEEVFHLVRLRSGDGEPISIEDTYIPLNLIPDLQAFDFQIFSFYS
                     TLAAYHYQIENIYQTISSSKVSNKEARLLKTSLNRPVISLAITAVTTNEQAVEYTEVV
                     VLPEFAAIYTKNVHQGKEMKIYAQID"
     gene            4897..5607
                     /locus_tag="IV356_002749"
     CDS             4897..5607
                     /locus_tag="IV356_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP9016369.1"
                     /translation="MPKLINLLAYDLIDKIIAYIHEHHLTPGTKLPSERDLSEMFNVN
                     RTTLRGALQKLVDNGTLRAQTNSGYYLTAPKFEKNAHHFFTPIEDSLLSKQRLQLKAT
                     ALSPKKAAALCPELNDFKQQQPQAYLEYIDAEAISLMLLIPMETLKKSNFSDNPFQDF
                     KSLAYTRSQEISLITDNDVAADLLGVDKEEVLLFVREEIRAGKELAAIALGYTISRRC
                     NIQVNVATTLQSGSVAKF"
BASE COUNT         1832 a         1195 c          943 g         1719 t
ORIGIN      
        1 aagcgacaaa aaccacgagc aggtccattc atcctcaaac ctcggtgatc ttcgcggttt
       61 aacaccatca gaagaaatgc acaaaaataa taaggagagt ctgagacata aataaattcc
      121 cagactttta gtgagtctaa atccgaataa acggtgggtc gaaagcaact ctagctgcgc
      181 gtcgatcgca gcaatctcta ggtgctatgt tcggataaat ggtggtcaaa agtcagattt
      241 tcggccattt cgtaacagcc aaccagacaa aaagcgtctg ttttgtcttc tactccaatt
      301 gctcaaatct tagcgacttt tggcttggtc ttactctaaa cagtttgtaa gcctaaactt
      361 tatttgctgt ttgtttctaa gatcaaagca aaactacttt ttagttggtt acttttacaa
      421 gttcttttta ctgttgaata aatgtaaatc ttaagaacaa atatttactt ctataattcc
      481 aagtttctta aaaaattccg ccaagtgtac ctaaaaagca taaaacaaaa attcctagaa
      541 taattgtgat cgttttatgc cctttggagt aaagccagac gcataaaaag gtaattccta
      601 atggcagcaa gcccggaaaa atttgatcaa aaatactttg taatgaagtt tcagctccac
      661 caaccgtgaa ttttagtgac gtatttaaag taaccatcgt gcctatcatc gcgccaatta
      721 ccgttaaacc taaaatcgaa gcaccatgag ataatttgtc aatcatatgg ttgtcttctg
      781 tatcatcaat aaatttagtt cctaaaacat agccatattt tgtcgccaac catttaaaaa
      841 taaaatgaat ggcagtatac aaagtaaaat aaaggatcat gcctaaaata ttcccttgtt
      901 gagcaaaaga aatacctatg ccagccgcaa taacccgaaa agttccccag aaaaatgaat
      961 cgccaatacc tgataaaggt cccattaatc ctgttttgat tttattaatt gcgtctgtat
     1021 caaattcagg atttttagca ttttcttctt ccatggtgac ggacaagctc ataacaaaag
     1081 gcgcaatatg cggtgtaatg ttaaatgttt ccgtatggcg ctgcaacgct gtataataat
     1141 catcatcgtt cggatatatt ttacgtaagg aacgttcaat accattcatt tgtccatatg
     1201 ccatcatttt atcgaaggac caagaggatt gcataaaaaa ggagcgccaa aatatacttc
     1261 ttaattcttt tttcccaata acactttctt ttaccattat aaatcttcct cctcttcaaa
     1321 agttagcttt tgaacagcca gtaacgctaa gcaaagtccg acgacagcca caccgacaac
     1381 atccattttc agatacatta cgccgacaaa tcctaagaaa agataaggca tcatcgcttt
     1441 attcgccatc attttaatta ataacgctag cccaacacaa gaaagcacac cggccgcaac
     1501 atcaaagctg tccaatacaa cctgaggaat caacttgatc atcgcattga ttgtagacac
     1561 accaaaataa gtagctacaa aaactaaaat ggccgatgga accccaacga ttaaaggttg
     1621 agccacataa tgatattttt gtgctttttt gaaatcatga ttgactaatg cctcatccat
     1681 tttgttgtta aaatacgtaa ttggcattgc ataggcgaag ttacgccaca tctgaagaaa
     1741 gatggacaaa ggtaaagtca acgcaacggc agttcctact ccttgacccg attgaatcgc
     1801 aattgctgta cctaaaacac tggaagcata aacttcaggg ggcgtcgcac tccctaccat
     1861 aattgagccc atgaacatgg attccaaggt ggcaccaata ataattcctg actctaaatc
     1921 tcccaaaatc aaaccgacaa aaggcgctgt aaatagcggt ctacccatca tcgatgcacc
     1981 aaatgtgtat tcatcaatag acgccaaaaa agctaccagt gcgattaata ttgcttgtat
     2041 catattcttc ccctcctctt ttagtcatgc aaaggattga tttttttgtc cgttggtaca
     2101 gcctgacatt gaactgttat cccgttttca gtcatttttt tcaccaagtc cagttcttgt
     2161 tcattcaagt aaacggaact agtaatcatt ttccgattct cgtttttctt taaatttcct
     2221 aaattcactt ctttaatctc aggtacgtgc tgagtaattt cgtaggcatc ctccaccgtc
     2281 ccgacaatta aaaatacttg gtatttcttg attttttctc catttaaaac agagatggcc
     2341 tctgtcatat ccttcaccac aaattttgtc cctgtaggaa cagccatttt tagtgttttt
     2401 ttgcgcagat tattggtagc gatttcatta cttgcaacga aaatacaatt tgcacctaag
     2461 ttatttgtcc aggcaaaagc aacttgccca tgaacaaaac gttcatctac tcgtaataat
     2521 ttaatcatta aaaatcatcc tcttctgttt tctctagcaa ctcgttcacc aaaactatcc
     2581 cttcattccc gctattcata gctttttgga ttagtttttt cgtgtcctgt tcacctgata
     2641 agcaaagctc taaaagcagc ggcagattta caccgctgat taaataaaaa ttgtctttac
     2701 cgatttgttc ggagaaagcg ttagacacgc ttcctcccag taaatctacc gtcacaatta
     2761 attcgtcatc aggcgctaag tcggaaaata gctgctctat ttcctggtta atggagtagt
     2821 cactatctat atacgcagtt attgctaaaa gtgatttttg aggaccaata ataaattcta
     2881 aagtatcctt taagccttta gccatcatgg aatgcgtcgc aattacaatt ttcctcatag
     2941 ctcttacctt aatattccac agtccgataa taacgacgaa tatctagtga atgatcccgc
     3001 accttttcaa aatgagcact cactcgttct aaggccgttg ccataaccat tggcgctaca
     3061 tactgacgca tagcgcttgg tacacctgct aattcgaaat ccgcagtgtc aaaaaccgtc
     3121 acaacatcgc tatatttatt tacaaaacgc tctacgcgat cgactagcgg acgcgtttga
     3181 tcttcacctt ttaataacac aaaactcata gatttatcag tcatttcaat agtcccatgg
     3241 aaaaattcgg ctgcatggat cgacttggtg gcaatccatt gcatttcttc cagtacgcac
     3301 atagcatatt cataggcagc cccataagta ttcccggctc caacaaacat atgaaattcc
     3361 gtatttttat gtttttctgc aaattcaagt gctttctgat cattttgttg ccgaacactt
     3421 agtaatactt ccggcatttt ttgtaatgtt tgaataaatt catcatattc aggaaactca
     3481 ccgttatttt tcatcaggcg tgcacccaaa gcaaaaaact gtaactgaag ttcttctact
     3541 aatgtatcgt tgtcagcatc attttcaatc gcataatcca cgatttcccc gagtggtgta
     3601 gcagcatttc ctacaaacgc aatcgtcgtt gcaccttgac tattggcata cttaacaaca
     3661 tcaacggttt cttgagtcgt accggttaat gaagatgtga ttaacactgt atctttatta
     3721 atctttttcg gctgtgaaca aaccacctct gcggctattt catgataata atcaagctct
     3781 gaatgagtgc ttaacagata agctagcggg ctgattgtgg catatgttcc accagagcct
     3841 accaaataaa gatttttaaa tcccttctca ctgattgcat ctgccacctg attgattgtc
     3901 tcgatatttt ttactgcacc atttaatact gatagaaaac gttcttcgct aaaacctaac
     3961 atagttaaaa acctccaagt caataatttg aaaaatatat ttgcaaatgc cggcacatta
     4021 acaaaccact taaccttttt tatataccac ctgttaacgt ttttaatgta ccacttatag
     4081 aaaacgctgt caatagtttt taaccacttt tatttttatt tgtaccaaaa tccttttttc
     4141 atgtataata aacaaaaata gactctggag tgtaacgtat gaatactgaa gaactaacga
     4201 acaaattaat acaagacatt gaacaagaaa aatataaata cgcgcaagct attccttcag
     4261 aacgtgattt tgttcaaatt tatgaaatga atcgttcagc cgtaaaaaaa gccattcaac
     4321 aattagtaaa taaagagtac ctactaaaaa tacatggcaa aggaactttt gttaaaaaaa
     4381 atatccatga acatttgcaa atcaaatttc atggtttgtc tgaattgttg gaacgggaag
     4441 ggattcagcc tagcagctta attttagctt cagaaataaa accggctgga cacattgtcg
     4501 ggaaagcttt acagctggaa ccaactgaag aagtatttca tttggttcgt ttaagaagcg
     4561 gcgacggtga gccaatttct attgaagaca cttatattcc attaaatctc atacctgatc
     4621 ttcaagcttt tgatttccaa attttttcat tttattccac attggctgct tatcattatc
     4681 aaattgaaaa tatctatcag acaatttcca gctcaaaagt gagcaataaa gaagcccgtt
     4741 tgttaaaaac cagcttaaat cgtccggtaa tcagccttgc tatcactgcg gttacgacaa
     4801 atgaacaagc ggttgaatac actgaagtag tggttttgcc tgaattcgcc gccatctata
     4861 ctaaaaatgt tcatcaagga aaggagatga aaatctatgc ccaaattgat taatctgttg
     4921 gcttatgacc tgattgacaa aattattgct tatattcatg aacatcattt aacccccgga
     4981 acaaaactgc cttcggaacg ggacctatca gaaatgttta atgttaatcg aactacctta
     5041 agaggcgcgt tacaaaaact ggtggacaac ggcaccttac gggcgcaaac caatagcggc
     5101 tattatttaa ctgcgccaaa attcgaaaaa aatgcccatc atttctttac accgatagaa
     5161 gattctctgc ttagtaagca gcggctacag ctaaaggcaa cggctctttc accgaaaaaa
     5221 gcagcagctc tttgtccgga actgaatgat ttcaaacagc agcaaccaca agcttattta
     5281 gaatatattg atgcagaagc aattagcttg atgttattaa tccctatgga aacattaaag
     5341 aaaagtaatt tctcggacaa tcctttccaa gattttaaaa gtttggcata tacgcgttct
     5401 caagaaattt ctttaataac tgacaatgac gttgcggcgg acttgctggg agttgacaaa
     5461 gaagaggttc tgttatttgt acgagaggaa ataagagccg gtaaggagtt ggcggcgatt
     5521 gctttaggtt atactattag tcgccgctgc aacatacagg ttaatgttgc tacgaccttg
     5581 caatccggtt ctgttgcaaa gttttaaatc tactatcaga taaggtagaa taatagaaaa
     5641 agatagcagg aggaatgacg atgagtcatt ttaaaggaaa gcaatttca
//
LOCUS       DACDLM010000120         5573 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.122, whole genome shotgun sequence.
ACCESSION   DACDLM010000120 DACDLM010000000
VERSION     DACDLM010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5573
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.122"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            137..748
                     /locus_tag="IV356_002750"
     CDS             137..748
                     /locus_tag="IV356_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAP9016370.1"
                     /translation="MYFILPTLYSLLCVMAPCIIYMVFFCKKNTLKHNILILIFMLYC
                     WKVFELTGTGGLTDIFYRPDTGRKFSLVQGSVNLVPFSGLNISFILNIVMCVPLGFLL
                     PIIWKSYRKIVPVFLAGALFSLIIEVSQIITTRATDIDDLIANTFGAVIGFILWAVLS
                     RVVSLKDKSSTVDYLEPYIYILIGFTGKFLLYFPFWFAFEVLS"
     gene            821..1750
                     /locus_tag="IV356_002751"
     CDS             821..1750
                     /locus_tag="IV356_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HAP9016371.1"
                     /translation="MKRFLKWGLVLLASLIVILMCTAVVISYVNRPYARAVYDRIKRI
                     LDKDFYDHLYLGSSFEIINLDTMDIHSYMKKDQEELPASLSKLFTIDYALSVLSLDEQ
                     ITISPTALDMQKADSSTAHLQEGDILSVYDIICAMVLPSGNDAAYSLAIYTGGKLDPD
                     AKNDEERYQSFMKNLDRYLSEQGYKHTHFTDAAGYDSNATTSAEDLTKVAAKLLKNDK
                     FAEIVAKETYRAKSIKGNVYNWNTTNQFMQQDNRYFTEGVKGVKTGSFDGRYNLCVYY
                     TSSSDNHYLLVSFGSESDSRRYVDVQNLLHNLP"
     gene            1908..2645
                     /locus_tag="IV356_002752"
     CDS             1908..2645
                     /locus_tag="IV356_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="HAP9016372.1"
                     /translation="MLISCGARLAPFDIRELRELMSEDELELDKIGDRKTALFVIISD
                     TDDTFNFVVSIMYSQLFNLLCDKADDVYGGRLPVHVRCLLDEFANIGLIPKFEKLIAT
                     IRSREISASIILQAQSQLKAIYKDHADTIVGNCDSTLFLGGKEKTTVKELSETLGKET
                     IDLYNTSETRSNQKSFGLNYQKTGKELMSQDEITVMDGGKCIYQLRGARPFLSDKFDI
                     TKHKNYKLLEDYDKKNLFDVEEYLKQR"
     gene            complement(2693..3871)
                     /locus_tag="IV356_002753"
     CDS             complement(2693..3871)
                     /locus_tag="IV356_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP9016373.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHHYTPQTMSNMTKSFTEEVTSFKERELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILIDLQERG
                     VKNVLLFITDGLKGMAGAVQRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKKAALEARGAFAEKWKTSYPKMVESILSNDYLLTFYDFPLAIRKTIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQVTDTLASMFTE
                     "
     gene            3894..3977
                     /locus_tag="IV356_002754"
                     /pseudo
     CDS             3894..3977
                     /locus_tag="IV356_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
     gene            4098..4499
                     /locus_tag="IV356_002755"
     CDS             4098..4499
                     /locus_tag="IV356_002755"
                     /inference="COORDINATES: protein motif:HMM:NF013068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016374.1"
                     /translation="MSDKFSKKISSDIKEDFKAIFKTASIELAGERKQLIMDKYGEDK
                     KVATACKILDEGFEDAMQVMVLPENIRQRLRTTNVLERLNEEVRRRERVVRIFPNCDS
                     VIRIIGALLMEKDDEWTSAPRKYLEFDRNEI"
     gene            complement(4706..5086)
                     /locus_tag="IV356_002756"
                     /pseudo
     CDS             complement(4706..5086)
                     /locus_tag="IV356_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629715.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            5268..5573
                     /locus_tag="IV356_002757"
                     /pseudo
     CDS             5268..5573
                     /locus_tag="IV356_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
BASE COUNT         1776 a          935 c         1081 g         1781 t
ORIGIN      
        1 cctctaggaa aaaattaact agcaccacgg gttatgatat aataaaatgt attataggca
       61 tttttttaca agaaatagaa gcttgaagtt tatatgaagt tataaaattt aatttatatt
      121 ggaaggagga aaataaatgt attttatact acctacactt tatagccttt tatgtgtaat
      181 ggcaccatgt attatttata tggtattttt ttgcaaaaaa aataccctga aacacaatat
      241 cctgattttg atttttatgc tgtactgttg gaaagttttt gaattgactg gtacaggtgg
      301 actaacagat attttttata gacctgatac aggtaggaaa ttttctctag tacagggcag
      361 tgttaatctt gtaccattca gtggactaaa cattagcttt atattaaata tagtaatgtg
      421 tgtgccctta ggattcttac taccaatcat atggaaaagt tataggaaaa tagttcctgt
      481 tttcttggct ggggctctat tttcactaat tattgaagtc tcacaaatta taactacaag
      541 agcaacagat attgatgatt taatagcaaa tacctttggt gcggttatag gctttatact
      601 gtgggctgtt ttaagtagag tggtgtcctt gaaggacaag tcatctacag tagattattt
      661 agaaccttat atttatatat tgattggttt taccggaaaa ttcttactgt attttccttt
      721 ctggtttgct tttgaagtat tatcctgata attccataga aaataatgag tttgagttga
      781 gaaagaatat tcttgtacac aactctggaa aggaggaagt atgaaaagat tcttaaaatg
      841 ggggcttgtt cttttagcgt ctttgattgt gattctaatg tgtacagcgg ttgttatttc
      901 ttatgtgaat cggccgtatg caagagctgt ttatgatagg attaaacgca ttcttgacaa
      961 agatttttat gaccatctat atctaggttc ttcatttgaa ataataaacc ttgatacaat
     1021 ggatattcat agctatatga aaaaagacca agaagaatta cccgcctcat tgagcaaatt
     1081 atttacgatt gattatgcgc ttagtgtcct aagtttagat gaacagatta caattagtcc
     1141 tactgcactt gacatgcaga aagctgactc atctactgca catcttcaag aaggagatat
     1201 tttatctgtt tatgacatta tctgtgctat ggtcttaccc tcaggaaatg atgcagctta
     1261 tagtttggca atttatacag gtggaaaact tgatcctgat gcaaagaatg atgaagaacg
     1321 ctatcaaagc ttcatgaaaa acttagatcg ttatctaagt gagcaaggct ataaacatac
     1381 tcattttact gacgctgctg gctatgactc caatgctaca acatcagcgg aagatttgac
     1441 aaaagtagct gcaaagctac taaagaatga taaatttgca gaaatagttg ccaaggaaac
     1501 ttatagagca aaatcaatta agggaaatgt ttataactgg aatactacga atcaatttat
     1561 gcaacaagat aatagatact ttactgaagg tgtaaaaggt gtaaaaactg gatcgtttga
     1621 tgggagatac aatctatgtg tgtattatac atctagttct gataaccact atttacttgt
     1681 aagttttggt tcagagagtg atagtaggcg ttatgtagat gttcaaaatc tattgcataa
     1741 tctgccttga aatttcgtgc ctttaagcgc gtatctaaag tttctttgaa aagtttgaga
     1801 atgaagaaag tgagcagtcg aaaaacggtt gctcactttt ttgccctaaa atcgaaaaaa
     1861 tataaaaaag tcctttacaa cacgtctcag gaaaaactgc taagtcaatt ctaatatctt
     1921 gtggagcaag acttgcacct tttgatataa gagagcttag agaactaatg agcgaagatg
     1981 aactagaact cgataaaatt ggagatagaa aaactgcctt gtttgtaata atatcagata
     2041 cagatgatac atttaatttt gtagtttcaa taatgtattc tcaattattt aatctactat
     2101 gtgataaggc agatgatgtg tatggtggaa gacttccagt tcatgttagg tgtctacttg
     2161 atgagtttgc aaatatcggt ttgattccta aatttgaaaa actaatagcg acaattcgtt
     2221 caagagaaat atcggcaagt ataatactgc aagcacaatc tcaattaaaa gcaatttata
     2281 aagaccatgc agatacaata gttggtaact gtgactctac actttttcta ggaggaaaag
     2341 aaaaaacaac agtaaaagaa ttatcagaaa ccttaggaaa agaaaccata gacctatata
     2401 acacatcaga aacaagatca aatcaaaaat cttttggtct aaattatcaa aagactggca
     2461 aggaacttat gagtcaagat gaaataactg taatggatgg tggtaagtgt atttaccagc
     2521 taagaggagc aagacctttt ctatctgata aatttgatat tacaaagcat aagaattaca
     2581 aattgttgga agattatgat aagaaaaact tgtttgatgt agaagagtat ttaaaacaaa
     2641 gatagcgtaa aatattttgt gtaaataact cgtccttctg caaaataatg ggttactcag
     2701 taaacattga agctaatgta tccgtcactt gttggaagcc tttatggctt ctatttaaga
     2761 atttttgatt gtatgtatca aagatggata ctaggaaacg ctctagtgat tcttcatttt
     2821 gaaactgctc ttttctgtgg ctgtatttct tgatttgctt attaaaggat tcaatcaagt
     2881 tcgtagagta aatagtcttg cgtatggcta atggaaaatc atagaaagtg agcaggtaat
     2941 cgttcgaaag gatcgattcc accatttttg gataactggt tttccatttt tccgcaaaag
     3001 caccacgtgc ttccaatgcc gcctttttag atgacgcttg atacaccatt ttaaaatcat
     3061 cacagacttc cttacgatca tcgacacgca ctttgtgact gatattacgg gaaacgtgca
     3121 cacagcaatg ttgaaaacgg gctttggggt agaaccgctg cacggcccct gccatcccct
     3181 ttaagccatc cgtgatgaaa aggaggacgt ttttcacgcc acgttcctgg aggtctatta
     3241 aaatctcttc ccaaatcgtg atagattcag ttggtgcaat cgcatagctc aacacttcct
     3301 ttgaaccgtc cgggcgaatg ccaactgcga tatgaatggc ttccttggcg acggttttcc
     3361 gctttaaagg gatataggtt gcgtccatat aaatagcggc ataacggtca tgaagctcac
     3421 gttccttaaa tgaagtgact tcttccgtaa atgatttagt catattggac atggtttggg
     3481 gcgtgtagtg atgcccatac attttctcaa tcaagtctgc gatttccgac atggtaatac
     3541 cttttcggaa gaggtgaatg acggtctcct ctaaggtatc attcgtccgt ctataagcag
     3601 gaacagtctg ttgcttgaac tcgccgttgc ggtcgcgcgg aatctggaga tgaagttccc
     3661 cgtactcggt cttgaccgta cggtcatagg agccgttacg agaattaccc gtgttaaaac
     3721 caatgcgatc gtacttttcg taatcgagga aagccgttaa ctccgttttg agaagcgtat
     3781 tgacagcttt ttccaaatgg acacggaata attcattcaa atcgccttta ttcgctagag
     3841 tctttagaat ttctgtagta aaatcgttca tatggaagtc ctcttttctg tgaatgtgtt
     3901 gtggtaactc tattctactg aagggacttc cttttttcta tttacacaaa atattttaca
     3961 ctctcggatt gaaagaacgc ggtctttcag gagtaaagat ggtcatctcg gatgcgcata
     4021 tagggctcac aaaagctgtg aaagaatacc ttctttgtgc gagctagcag agatgccaag
     4081 cacatctcct tcgcaacatt tccgacaaat tctccaagaa aatctcaagc gatatcaaag
     4141 aagactttaa agccatcttc aaaacggcaa gcatcgagct ggctggagaa cgtaaacaac
     4201 ttattatgga taaatatggg gaagacaaga aagtcgcaac tgcctgtaaa atattggatg
     4261 agggcttcga agatgccatg caagtaatgg ttttaccaga aaatatccgt caacgattga
     4321 gaacaacgaa tgttcttgaa agactaaatg aagaagtacg ccgtcgtgaa cgtgttgtcc
     4381 gaattttccc aaattgtgat tctgttattc gtatcatcgg tgctttattg atggaaaagg
     4441 atgacgaatg gacttctgca cctagaaaat atcttgaatt tgatcgtaac gagatttagc
     4501 acattaagcc gccaatagta taatatactg gtgagaagta tcaagagacg cttcgctttt
     4561 tgctcttgac acttcttacc agcatattgg accgtagcta ggctcaacaa ggcaaaacat
     4621 cgtactttga gatttccttt ttacacaaga ttttggactt gacacagccc ctatggttct
     4681 taccttgttt atgcttattt aaatcttact ttattacagt actttcaaac ttcgttttgt
     4741 aagccgggta ttttgatatt tcataattat gtccctcttt ttgaatatat tctttgatat
     4801 ctgcttgttc atctacactt tctttgcgta aaatacgttc gatcattgag cagcagtgca
     4861 tgtaaagcaa gaacaattga ttgtttgaaa attcgatccc cattagtttt tcgagttctt
     4921 tgacggcctt ttgtaccaat ctcaaaacct tcattgcatc aaggatcgtt aaattttcta
     4981 cgatcttgtt aatcgagaaa ttaaagtatt gagcacaatt ataggcgata aatggagcat
     5041 ttgattctat cacctgttgt tccttggcgt attcataaat tttttctgcc aaaaaggttt
     5101 ttcctgaacc gcttacaccc atcaataaaa tcggtaatcc gttatgagga tacaagacag
     5161 ccgtcttgat ttgatcgatc gcttccttta aacggttctg ttgcaaagtt ttaaatctac
     5221 tatcaaataa ggtagaataa tagaaaaaga tagcaggagg aatgacgatg aatcatttta
     5281 aaggaaagca atttcagcag gatgtgatta ttgtagccgt gggctactat cttcgttata
     5341 accttagcta tcgtgaagtt caagaaatct tatatgatcg tggcattaac gtttctcata
     5401 cgacgattta tcgttgggtg caagaatatg gcaaactact ctatcaaatt tggaaaaaga
     5461 aaaataaaaa atccttttat tcatggaaaa tggcattatt tgtatcgagc catcgatgca
     5521 gatggtttaa ccttggatat ttggttacgt aaaaaacggg acacacaagc agc
//
LOCUS       DACDLM010000121         5561 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.123, whole genome shotgun sequence.
ACCESSION   DACDLM010000121 DACDLM010000000
VERSION     DACDLM010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5561)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5561)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5561
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.123"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(28..579)
                     /gene="raiA"
                     /locus_tag="IV356_002758"
     CDS             complement(28..579)
                     /gene="raiA"
                     /locus_tag="IV356_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HAP9016375.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            complement(707..1426)
                     /locus_tag="IV356_002759"
     CDS             complement(707..1426)
                     /locus_tag="IV356_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HAP9016376.1"
                     /translation="MRCSCCSKDIFQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            complement(1423..2736)
                     /locus_tag="IV356_002760"
     CDS             complement(1423..2736)
                     /locus_tag="IV356_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAP9016377.1"
                     /translation="MNHFWGRRLLTRDIEAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEISKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            complement(2817..3137)
                     /locus_tag="IV356_002761"
     CDS             complement(2817..3137)
                     /locus_tag="IV356_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP9016378.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            complement(3245..3532)
                     /locus_tag="IV356_002762"
     CDS             complement(3245..3532)
                     /locus_tag="IV356_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016379.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            3659..4303
                     /locus_tag="IV356_002763"
     CDS             3659..4303
                     /locus_tag="IV356_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HAP9016380.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            complement(4362..5069)
                     /locus_tag="IV356_002764"
     CDS             complement(4362..5069)
                     /locus_tag="IV356_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP9016381.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
BASE COUNT         1605 a         1168 c          956 g         1832 t
ORIGIN      
        1 ttttcgttgt tatttaagta aggctgatca gtctgtttca atcagtccgt attttccatc
       61 tttacggcgg taaacgatac ttgtaccatt tgtttctgca tcttcaaaaa taaagaagtt
      121 atgtcccagc atgttcattt gtaagactgc ttcttcacta tccattggtt tcaatgaaag
      181 gcgtttcgta cgtacgatat ctaattcaga atcattttcg ttttcgtcct cttcattgaa
      241 taaagcagca gcatctgcag tattcatgcc cgtttcacgg gatttacgat taatttttgt
      301 tttgaatttg cggatttggc gttccaattt atcaacaacc aaatcgatac ttgcgtataa
      361 atctggagaa gtttcttcgg cacgtaatac aagataaggt aatgggatcg ttacttccac
      421 ttttgctgtt ttttctgtat aaacttttaa gttcacatgc gccgttgcat cgggtgcgtc
      481 actgaaatag cgttctagtt tgcctacttt tttctcaacg tagtcgcgaa tcgcttcagt
      541 tacttcgata ttttcgccgc gtacattata tctaaacata aaaattaccc ctttcgtcta
      601 ccacaatcaa gaaggagaag gaccactctt tccctcttct taattctatt atatcgaact
      661 ctaggttatt tgcaaattaa atcgctatca aatttccaca tctaattcat ctcgccaaag
      721 aaatggttcg gatgattttc ggctgtgcga cctgcaaaca atctgctgcg tggaaaagag
      781 tctgtcctgt tgtatagaca tcatcaataa tcaatatttt tttattttgt atcttagaaa
      841 aggtgactgc aagttcaaaa ggttgaggca tctccaatct ttcctttcgc gtgttttttg
      901 cttgagccag cagatgcttc tctcttttga gtagcatctg aaaaggaatt cttgctgctt
      961 tcaacatctc gcttacttga ttgaatcctc tttctgttcg ccttttttca gataaaggta
     1021 ttggacaata gatgtatgtc gggtattctt tttttatctg cgtccattta tatgcaaagg
     1081 tgcctgctag tcggatatct cccataaact tgtattgatt gagccaggcc ttcatatttt
     1141 catcgtacac aaaaaaggca cggtgctgaa aatcataggt cggatatttc ttcttccatt
     1201 cttgacagtc actgcagtaa acgggaatag actttacttt ctttttcgta ctctctagat
     1261 tgaaatggat tggtttttga cagccagaac agcctcttgt ttccaataaa tgaaattgtg
     1321 cgcgacaaac tgaacaagtc tgaggtaatc tgtatttcga aacaccaata atctcgctga
     1381 atgttaaatt ttggaagata tctttactgc agcaactgca cctcacagca tcttcttccc
     1441 ttcttcattc atttctttga tttcctgaca agcttttcga atagctgcag ttttttcttc
     1501 atagaaaaag tatacttgac tgttcgtata aggcccttta cgatcggctc ttcctgcgat
     1561 ttgtaccaaa gaagatttag taaaaaccgg atgatccgct cctaaaacga taacggatat
     1621 tctttcaaat gtgactccac gttcaaggat catcgtggtt aacagtatat catattttgc
     1681 ttctcgcatt ttctggactt tttccgcccg ctgattgtct cttgaagaaa catctgtgat
     1741 ctcatatctc ggaagagcct cttgaagtgt ggctttcaaa cgatgcatca tcgtgatact
     1801 tggacaaaat aaaaggatat ggttttcttt aattaattga tgaatgatcc gcaccaaaga
     1861 ttttatcttc ttcttgttct tgcatttttg tcgccaatta ttcatgaaaa ccaagacggg
     1921 ttcaggaagc aaacgccgat gaaagcgtaa agcaagtttg tggatgtcaa acgtctgctt
     1981 gatttccttt agtaactttt tatcaggtgt ggcacttaag tagatgaatc gtccgtctgg
     2041 tttaatcgct gtttgcacag catgagctaa tcctgcatcc ccgttataag gaaacgcatc
     2101 gatctcatcg atcactatta aatcaaagga ccgataaaaa cggtatagct gatgaatcgt
     2161 acagataaca aaagaagtaa aggtataagc cgttgctgta ttcccatgga gcaacgtgat
     2221 tttttcttct ggaaaaacat aacgatagcg taaaaacaat tcattacaaa catcgactcg
     2281 cggtgtacaa atcgctactc ttcctccagc ttttaaagtt tccactaaaa taggataaag
     2341 catctctgtt ttccctgcac ctgttacagc ccaaataaga tgatgtcttt tttctgaatg
     2401 gcaaagtatt ctctttgaga tttccgtttg tttttcagta agctgtcctg tccaaaaaaa
     2461 gacgacttct cgaggttttg cttcaggctg atcaaacaaa tataaatctt gttgagtgtc
     2521 gcatcgccct aaatatagac aatgtgtaca aaaataaccg taatctgcaa gctgtccatc
     2581 aatgacggac gtcctcattc cacagcgatg acaaagaatc cagttgccca aacgttccac
     2641 tgctgcgatc ttctcataat ttggtaaatt tacctcctca cagtctattg cttcaatatc
     2701 tctcgtcaga agccttctac cccaaaaatg attcatattc ttcgccctaa aaaaatatac
     2761 gaaaaaacaa gcgatctatt ttttggatcg cttgttcgat agttatactg ttctatttat
     2821 tcacctatga gcgtgattgc ttgatctaac actttttcgc cattcatcat accataatca
     2881 gccatattga tgacatctaa aggaatgcct tttggttcca gacgtttctc aaaatcagct
     2941 ttcataaagc gaacttgtgg gcctaataac aacacatcca cgtctttatt tgcaaggttg
     3001 ttatctgcgt cagaagcgga cacagcgaaa atatccgagt cgattccttt tgcttcagca
     3061 gctttttgca tttttgttac tagtaaactt gtgctcatac cagccgaaca tacaagcatg
     3121 attgtttttt tagccatact tttctctcct ttttaaaaca aactatgcaa acgttttctt
     3181 cgcgtctgtt actctattat ataaaaagaa agaaatttgt caacgttttc taaacgcggt
     3241 ttatttaatc aaatagccaa ctagatttca ctaatttatt gaacacgaca tattctttgt
     3301 ccaaattgat gacaactact tcatagcctg catttatcca gccataggca cctttttcag
     3361 ggtgtttata atcatttgcc caccaatctg tactttccct tgctgttttg ggaagtccgt
     3421 tactgggaaa cagcagttcg tcaaattggg taaaggtcaa cgttacttga gagccgccat
     3481 tgttcttcaa ataatgcgta attgcatcgt actttttcat tcgttcctgc atccccagat
     3541 ccacctgcct ttgtctttat tatcgcatac tacagcaatt gcgcaaccgt tacagtgttg
     3601 aaacaaccta gaactttatt tatactgaat aaagaaaatg aaaaaaagag gtgacaagat
     3661 gatcgagcgc tatcgtacaa taaaagaaaa tggacaaagt gagattgaga tcaaaaaatc
     3721 acgctttatc tgttctctta gacgaataga atcagaggac caagcaaaaa gtttcattca
     3781 agaaataaaa aaagaacatt ggaaagcgaa ccataactgc agcgccttca tcattggaga
     3841 aaaaaatgaa atccagcgaa gcagcgatga tggagaacca agtggaacgg cgggcgtacc
     3901 gatgttggaa gtcctcaaaa aaaatcaact gatcaatgta gctgcagtag tcactcgata
     3961 ttttggagga acgaaactcg gcacaggcgg attaatacga gcatacactc atgcggtctc
     4021 tcaagcattg tctgacattg gaatcgtaga aggtaccttg caacaggaga tctctgtgat
     4081 gatcacgtat ccgcaactag gaaaattaca gaattatctt gaactccaac atttttttat
     4141 aaaagaaatc caatatactg atcaagttag cgtcatctgt gctgtagatg aaaaaagtgc
     4201 tgaccacttt aaagaatcca tcattgagct gctgaacgga caagtccaat ttgaagaggg
     4261 ttctgtttct tatcacgagc aactgataac tgatcatata taaaaacagg tgattctgat
     4321 tctcttttat ttctaataag gaatcaggga tcacctgttt tttatttttc caaataaaac
     4381 tcaaaacgat ttcctacgta ttgcgtacgc acatactcaa acggcgtacc gtcttcaaaa
     4441 taagaaatct ggcgcaaacg aagaactgca tctcctcgtt ttacctctaa atagtcagca
     4501 attttctcag aagccaacac agcagtaatc gtttgattcg ctggaccgat ctttttcccg
     4561 cctttttctt ctagcgtgcg atacaacgat tcagtaatct ctgctttgct gtagccatcg
     4621 atcagctttt gtggaacact ggcaacttca aaacaaatag ggacatcatc tgcgaaacga
     4681 atacgttcca ttcgcaagat cgtgtcatct ttactcaagt ttagtttttc catttcactt
     4741 gagcttggcg aagtcaagaa ataagagatt gtccgactag acggtactcg attttgtgat
     4801 tccataattt ctgtaaaact tgttgcacca gacatttttt cttgtacttt ttctcgcgca
     4861 acatacgtac ccgaaccgat ctttctttct aagattcctt catctgccaa gttttgaatt
     4921 gcttgtctca acgtcatacg gctgacattg aatttcactg ctaattctct ttctgaagga
     4981 agacggtctc cgactttcca tataccctgt tcgatttcat tttttaattg gtcatgaatc
     5041 tgtatatata caggtaattg attcgacata acgtacaccc gtcctttcgt ttcttctatt
     5101 ataactggta tatacctgat tcacaactga aaaagataaa ggtttctatc catcaacaga
     5161 ggatttagac acacatcgtt ctccctactc ctattgtcag aaacaatttt ttagatatgt
     5221 tcaacctaga aaataacaaa agaccctaaa atcgatgaaa atgccgactt atggatcttt
     5281 tgttattatt agcggttttt agccatccat ttttttgtat gattcgttgg gcgttttgat
     5341 tttacctgga ccgcttttcc gccttttttc ggaatattca cttcaatatt gtatttttct
     5401 gatttgacca aatcatataa cttttcagct gcttcgtcta ctttttcttt ccatttcatg
     5461 tggatccctc caattcttgt agttaactta actctatctt aattcagcag aatcttcaag
     5521 gaacaaggta gcaaagcaaa aaaaagagct ctcgaactaa c
//
LOCUS       DACDLM010000122         5474 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.124, whole genome shotgun sequence.
ACCESSION   DACDLM010000122 DACDLM010000000
VERSION     DACDLM010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5474
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.124"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            393..1616
                     /locus_tag="IV356_002765"
     CDS             393..1616
                     /locus_tag="IV356_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HAP9016382.1"
                     /translation="MESYQFQVFKLVPSLERRGNRMKITEKNVNPKFETTESNLKKFD
                     LTVTLSNQLVDSIVEMDAMPQKIYLYAIGHLDPKNPPFNNTVKVSKKALFALMSSSSS
                     SSKHSRLKQVIEKLHQQSVIKIQRTKPNGKTEYKVISPLEITEFNDFSDAVSIKFSSS
                     IMPLLTNLEDHFTQYTFDQVVNLTSKYAISFFQLFTKDFNLYEANRDNLTWSTKSLDR
                     LKNPVFSIADLRKKFSIEKKYKAFRDFERRVIKEPIAQLNKYTDFKIDYELIKKGRTY
                     TNIKFLLTRTMSVPVPYKQEQRDPAYLKGTEDKTEKMNQSYLKAMNSKYTKLLIKNFL
                     ISSADLCDLKLMSRLQNKVYPLYDRLSKDRGFESVVNHLSYVATHKEDYTIKNTVKYL
                     EKSITSYLPYVNLYD"
     gene            1651..2418
                     /locus_tag="IV356_002766"
     CDS             1651..2418
                     /locus_tag="IV356_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAP9016383.1"
                     /translation="MKKDELTKYNEEFLATIDMKMDLKSYELYQLLFSYISPTKLKKT
                     GVVDLPVKAIINYMDVDQNLETELKTIVNTLQRQAVYEISNLDKKYKTYTTVSAIDRI
                     HWDLEEHSVSFSFSEDVIPLIVSIKKKYPFFVFEDLASFQKKYSIVLYKYLAMYYKKY
                     LIAKNKGDFEKAEIYKNPLIEIVKIREITKTENEYKTISNFDRRVLRESVEEINEKSM
                     LNIDFAKVRKGRNYNFAVQFNISSEFDEKTYREKKLG"
     gene            2610..3008
                     /locus_tag="IV356_002767"
     CDS             2610..3008
                     /locus_tag="IV356_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin HicB"
                     /protein_id="HAP9016384.1"
                     /translation="MKYFFCAVFEWKGNEYAVKFPDFPDLYTHGETLEDAFEMAQEVL
                     EGYLVLLELQEKEIPSPTPVQELNARIKRSENVNLFVVKANTKVAKARNKQNYDRKSV
                     TVEHYLNVLAAEENINLSKALNDLLREKLI"
     gene            complement(3314..3709)
                     /locus_tag="IV356_002768"
     CDS             complement(3314..3709)
                     /locus_tag="IV356_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016385.1"
                     /translation="MKQEKRKMKQTQTETVNDTLADQLAGYYKLFEMGKAQRLIHYLW
                     KYKILFLFWESTLTFSVLFYKSDFYNQHLVLGSFLLIYTILMLNLYTYITLEEHLVIS
                     DAGIERNIKRVSFKITLNKPTDKKLSEAF"
     gene            complement(3710..4087)
                     /locus_tag="IV356_002769"
     CDS             complement(3710..4087)
                     /locus_tag="IV356_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016386.1"
                     /translation="MKSKKETEPMKSTHLNYFSRTLINNLLKDTTGISVSTKHFANDL
                     IIFEDNNLRIEMFIEQATPNSIPEFCYTHTEKMKHAKSVKDVEALSESLTNALNLVKK
                     AKLLFEFQTDYHNELLAQSEILD"
     gene            complement(4077..4472)
                     /locus_tag="IV356_002770"
     CDS             complement(4077..4472)
                     /locus_tag="IV356_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin HicB"
                     /protein_id="HAP9016387.1"
                     /translation="MKTKNIFYPAIFEKEGEAYNIVFPDLPEISTFGNSLEEAYLNAK
                     DALGLALYSVPDAEFPKPSAVEELTLKANQVVVIIQLNIKLFRRSLNTKTIRKNVSVP
                     EWLVLLGKEKNINFSQLLQKALEEELLEK"
     gene            complement(4539..4724)
                     /locus_tag="IV356_002771"
     CDS             complement(4539..4724)
                     /locus_tag="IV356_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HAP9016388.1"
                     /translation="MPKTAREIVKILKSNGFKKTGQTGSHAKFYNSKTKRTVVVPIHN
                     GDVPLGTEANIWKQAGL"
     gene            complement(4806..5060)
                     /locus_tag="IV356_002772"
     CDS             complement(4806..5060)
                     /locus_tag="IV356_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016389.1"
                     /translation="MNYTDEEQITLEYVFTNEEGEEIEKVLIISTKDLEKALAYEPYE
                     STVTVIEFLDTYTSNDTWEIMNICNANNIQFAEKTNKSFY"
     gene            complement(5082..5327)
                     /locus_tag="IV356_002773"
     CDS             complement(5082..5327)
                     /locus_tag="IV356_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016390.1"
                     /translation="MWTLEGKTFAEIWTEFIEVPTRIDPITSEKVLDADFYNLKAGTS
                     LECVWMYLEEHFKGVTLGHVLYHNGAEWDAIGNIHFS"
BASE COUNT         1866 a          841 c          914 g         1853 t
ORIGIN      
        1 tataatatat attttaatct ttaaaacttt agcaacctcc aaaaaggctt tatatcaatc
       61 ttaaatagat tttagggtgg acataaagcg atgtgaatgt ggacaaaaag cgatgtggta
      121 ttccgaatat atccaaaaaa agaaaaagta tgtgaattta tttctaaaaa ctagaaaaat
      181 atttgttttt taattttggt aatttttata atttcgtatt tttttgaaaa ggatttttat
      241 tttgaaaatg ttctaaaata gcgatttctg ctgtattttc aatgaaattt gattggaaaa
      301 aataaaatgt gttttactga cattgagtta tgttataaat ttacgataca tttcttattg
      361 taacgtatcg aaaacaggtc tatacttatt caatggaatc gtaccagttc caagttttta
      421 agctcgtacc aagcttagaa agaagaggca atcgtatgaa aataacagaa aagaatgtaa
      481 acccgaaatt tgaaactacc gaaagcaatc taaaaaagtt tgatttaact gttactttat
      541 cgaatcaact tgtagatagc attgttgaaa tggatgctat gccacaaaaa atttatcttt
      601 acgctatagg acatcttgac cctaaaaatc cgccttttaa taataccgtc aaagtatcta
      661 aaaaggcttt atttgcgttg atgtcttcta gttcatcttc ttcaaaacat tcaagattaa
      721 aacaagttat tgaaaaattg catcagcaat ctgtcattaa aattcaaaga actaaaccta
      781 acggtaagac tgaatacaaa gtcatctcac cgctagaaat tactgaattc aatgattttt
      841 ctgatgcagt atctattaaa tttagtagtt caattatgcc tttattaacg aacttagagg
      901 atcattttac gcaatataca tttgatcaag tagttaactt gacaagcaag tatgcaatca
      961 gtttttttca attattcact aaagatttta atctgtatga agcaaataga gataacttaa
     1021 catggagtac aaaatcactt gatagattaa aaaatcctgt tttctccatt gcagatttac
     1081 gaaagaaatt cagtattgag aaaaaatata aagcttttcg agactttgaa agacgtgtaa
     1141 ttaaagaacc gattgcccaa ctgaataaat acactgattt taaaattgac tatgagctta
     1201 tcaagaaggg tcgtacttat acaaatataa agttcttgct tacacgtacc atgtcagttc
     1261 cggtacctta taagcaagaa caaagagacc ctgcttattt aaaaggcaca gaagataaaa
     1321 cagagaaaat gaatcaatcg tacttgaaag ctatgaatag caaatacact aaattactaa
     1381 tcaaaaactt tttgatcagt tctgccgact tatgcgatct taaacttatg agccgacttc
     1441 agaataaagt ttatccgctt tatgatcgtt tatccaaaga tagaggattt gaatcagttg
     1501 tcaatcacct atcttatgtt gctactcata aggaggatta cacaataaaa aatactgtta
     1561 aatatctcga aaaatcaatt acgagttatt tgccttatgt gaacctttat gattaacaac
     1621 tgaaaaaatg cgtgaaggaa ggaaaaactt ttgaaaaaag atgaactgac aaagtacaat
     1681 gaggagttct tagcaacaat tgacatgaaa atggatttaa agtcgtatga actttatcaa
     1741 ttgctgttca gttatatctc acccacaaag ctaaagaaaa caggcgtagt agatttacct
     1801 gttaaagcga ttattaatta catggatgtt gatcaaaatc ttgaaacgga actaaaaacc
     1861 atagttaaca ctttgcaaag acaagcagtt tatgaaattt cgaatctaga caaaaaatat
     1921 aagacgtata ctactgtatc tgctattgat cggattcatt gggatttaga agagcatagt
     1981 gtatctttca gtttttcaga agatgtaatt cccttaattg tctcaatcaa aaagaagtat
     2041 ccgttctttg tttttgaaga cttagcatct tttcaaaaaa aatatagcat cgtgttatac
     2101 aaatatttgg cgatgtatta taaaaaatat cttatcgcca aaaataaagg agattttgag
     2161 aaagctgaaa tatataagaa tcccctgatt gaaatagtta aaattcgtga gattacgaaa
     2221 acagaaaatg agtataaaac aatatcgaat tttgatagac gtgttttaag ggaatcagtt
     2281 gaggaaatta atgaaaaatc aatgctgaat attgattttg ctaaagttag aaaaggcaga
     2341 aattacaatt ttgctgtcca gtttaatatt tctagtgagt ttgatgaaaa aacttataga
     2401 gaaaaaaaat taggttaatg caaaatatat cttactcgtt tgaagatgct tcagacgtat
     2461 gctaagatat atagtgcctt gggagcaagg tattaatctc ctttagaggt taattagctt
     2521 gtgatcgcct atcaattttt ttggtaggcg attctttttt ttgaaacaaa aaagcaaaaa
     2581 ttatttttta attagagagg tgcaatgcga tgaaatactt tttttgtgca gtattcgaat
     2641 ggaaaggaaa tgaatatgca gttaaattcc cagattttcc agacttatat acacatggtg
     2701 aaactttaga agatgctttt gagatggcgc aagaagtatt ggaaggatac ttggtgcttt
     2761 tagagttgca agaaaaagaa attccatcgc ctacgcctgt tcaagagtta aatgcaagaa
     2821 tcaagcgatc tgagaatgtt aatttatttg tcgtaaaagc taatacgaaa gttgctaaag
     2881 ctcgaaacaa gcaaaattat gatcgaaaat cagtgactgt ggaacactat ttaaatgttt
     2941 tagcggctga agagaatatt aatctgtcga aagctttgaa tgatttgttg agagaaaagt
     3001 tgatttgatg tctctcagat gatcatatta agcaaaaaca gcttgtttta ggacgtatgg
     3061 atttaagaaa gacaaattat caaagaatat attaaaagct ctcagaagcc ttctgagagc
     3121 ttttaaattg ctatgtattg tactgcatct gctcaaattg attttctttt catgcttacc
     3181 atgtatctag ttttccatca agtaattttt agatatgtat taagtaataa atagcaaatt
     3241 tgcttgatat aagctcgaat taggtgcttt ataatgtgtt aggataaatt atacaagaaa
     3301 atgtcaaaag ctctcagaac gcttctgaga gctttttatc ggtaggcttg tttaacgtga
     3361 tcttgaaaga tacccttttg atgtttctct cgatccctgc atcgctaatt actaagtgtt
     3421 cttcaagtgt gatgtaggta tataaattaa gcatcaaaat ggtgtagata agcaaaaaac
     3481 tccctaaaac taagtgttga ttataaaaat ctgacttata aaaaagaact gagaatgtta
     3541 gtgttgattc ccaaaaaaga aacaaaattt tgtatttcca aagatagtgg atcaagcgct
     3601 gtgctttacc catctcaaat aatttataat aacctgctaa ttgatcagca agcgtatcgt
     3661 taacggtttc tgtttgtgtt tgtttcatct ttctcttctc ctgtttcaat taatctaaaa
     3721 tttcagattg agcaagcaac tcattgtggt agtcggtttg aaattcaaat aacaattttg
     3781 ccttcttaac gaggtttaaa gcgttcgtta gtgattcact taatgcttca acatctttaa
     3841 ctgattttgc atgtttcatt ttttcagtgt gcgtatagca gaattcaggt attgagttag
     3901 gggttgcctg ttcaataaac atctcaattc gcaagttatt atcctcaaaa ataattagat
     3961 cattggcaaa gtgtttggta ctaacgctaa tgccagttgt atcttttaat agattattga
     4021 ttaacgttcg agagaaatag tttaagtgtg tagatttcat aggttcggtc tcctttttac
     4081 ttttcaagca actcttcttc tagtgctttt tgaagtagtt gagagaagtt tatgtttttc
     4141 tccttcccta aaagaactaa ccattccgga acactaacat tttttctaat tgtttttgta
     4201 tttaagcttc ttcggaaaag tttaatgttt agttggatga ttactaccac ttggttggct
     4261 ttcaaagtta attcttccac tgctgatggt ttaggaaatt ctgcatctgg tacactatat
     4321 agcgctaatc ctaaagcatc cttagcgttt aaatatgctt cttcaagact atttccaaag
     4381 gtagatattt ccggtaagtc agggaaaacg atgttataag cttctccttc tttctcgaag
     4441 attgccggat aaaaaatatt ttttgtcttc atttcctcgc tccttttcta gtgtaagaga
     4501 ggatagtatg cctaatacca aataggaagg caaggctgtt aaagccctgc ttgcttccag
     4561 atattagctt ctgttcctag tggtacatca ccattgtgga tcggaacaac gaccgttctt
     4621 ttagtcttgg aattataaaa ttttgcatga ctgccagttt gtccagtctt tttgaagccg
     4681 ttagatttga gaatttttac aatttctctt gctgtcttag gcatagctac cctcccttta
     4741 caaaatctat tatacacatt gttgtgtatg taatcaatag aaaaagagga tgttttattg
     4801 caaaactaat aaaatgattt attggttttt tcagcaaatt gaatgttatt agcgttgcaa
     4861 atattcataa tttcccaagt atcattagaa gtataggtat ctaagaattc aatgacagtt
     4921 acggttgatt cgtatggttc ataagccaaa gccttctcca agtcttttgt tgaaatgatc
     4981 aagacttttt caatttcctc cccttcttca tttgtgaaaa cgtattccaa agtgatttgt
     5041 tcttcatcgg tataattcat attgtgttct cctttcttgt attaagaaaa atggatattt
     5101 ccaattgcat cccactcggc accattgtgg tataagacgt gaccgagcgt tacgcctttg
     5161 aaatgctctt ctaaatacat ccaaacgcat tcaaggctag tacctgcttt gagattgtag
     5221 aagtctgcat ccaatacctt ttcagaagtt atcggatcaa tgcgagttgg tacctcaata
     5281 aattcagtcc aaatttctgc aaaagtctta ccttccaaag tccacactcc ctatcaatta
     5341 attccaaaag caaatagaga aatcaagcga ccgtcaatag tcacttcaac aactgaaaat
     5401 gccgttgaaa cagttttaac atccacactt tccaatttcc cgatgaagga atttttgtgc
     5461 tttagaatag cttt
//
LOCUS       DACDLM010000123         5466 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.125, whole genome shotgun sequence.
ACCESSION   DACDLM010000123 DACDLM010000000
VERSION     DACDLM010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5466
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.125"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            133..1107
                     /locus_tag="IV356_002774"
     CDS             133..1107
                     /locus_tag="IV356_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP9016391.1"
                     /translation="MRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAGQYLFD
                     KELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGAMTICL
                     SNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWETCLNEF
                     DKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFMEMQWIN
                     SNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVLDQADF
                     DLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
     gene            1089..1550
                     /locus_tag="IV356_002775"
     CDS             1089..1550
                     /locus_tag="IV356_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAP9016392.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLILMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLNNSQKSMVHINSLLKDVS"
     gene            1600..2064
                     /locus_tag="IV356_002776"
     CDS             1600..2064
                     /locus_tag="IV356_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP9016393.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            2078..2827
                     /locus_tag="IV356_002777"
     CDS             2078..2827
                     /locus_tag="IV356_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP9016394.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            2827..3657
                     /locus_tag="IV356_002778"
     CDS             2827..3657
                     /locus_tag="IV356_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP9016395.1"
                     /translation="MENSTEKKRLITKKDLHKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTPFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
     gene            3657..4304
                     /locus_tag="IV356_002779"
     CDS             3657..4304
                     /locus_tag="IV356_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP9016396.1"
                     /translation="MIKALIFDMDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKI
                     GTTASIFDDIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIK
                     MAIASSSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEEC
                     LVIEDSYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
     gene            complement(4402..5178)
                     /locus_tag="IV356_002780"
     CDS             complement(4402..5178)
                     /locus_tag="IV356_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP9016397.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLTESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
     gene            5260..5403
                     /locus_tag="IV356_002781"
                     /pseudo
     CDS             5260..5403
                     /locus_tag="IV356_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608918.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
BASE COUNT         1872 a          739 c          973 g         1882 t
ORIGIN      
        1 attttattat ataaaattgt tataaaaaat tttttttgaa aaatagtatt gcaaaataaa
       61 gcaatttcat agataatagg tatcgtaaag ttatataact ttataatacc tattagagtg
      121 agggataaag aaatgagaca actacacaaa gaacagattg aaacagcaat ggcagcgtta
      181 aaggaaaaga caattgatca tgtatatttt acagcatgtg ggggttcaca agccgtttta
      241 atggctggtc aatatctatt tgataaagaa ttaactgtac cttgtcatgt ttatactgct
      301 aacgaattta actatgctat accaaaagga ttatctgaaa attctttagt tatcacttgt
      361 tcccattctg gcacaacacc agaaactgta gaagcaacaa aaaaagcaag agaatttgga
      421 gcaatgacta tttgtttatc taatgaagaa ggatctcctc tatgggaagc agctgaatat
      481 cctgttcact atgattgggg taaagatgtt gatgctagtg atttaaataa aggaattctt
      541 tatggtttat tatttaatat tttacttgtt ttagatggct ctaaaaaatg ggaaacttgc
      601 ttgaatgaat ttgataagtt aaatgatctt gttattgctg aaaagagcaa atttgaaata
      661 actgctaaag aatggggtaa aaaccaaaaa cgagataaaa ttatttacac aattggtagc
      721 ggtattaatt acggagaaat ttactccaca gcagcttgct ggttcatgga aatgcaatgg
      781 attaattcta atgctattca ttctggggaa tttttccatg gtccttttga aatcactgat
      841 tatgatgtac cattcatctt agtgaaaagt attggagata caagattttt agatcaacgg
      901 gtagaagact tcactaaaaa attcagtaat aaattaatgg ttttagacca agctgatttt
      961 gacttagaat ctatagatag tgtagcgaaa gaatatattg cagctgtact tagtggcgtt
     1021 gttattcgcc aaatggtaga agcgattgct tttgaaagag gccattcctt agatgttaga
     1081 cgctatatgt ggcaaatgaa atattaatta ataggaggtt gcaaaagatg gcaaatcaat
     1141 tatttcacat tgtgattaca acacattcta ccctttgtga gggttattta aaggcaacaa
     1201 aattaatttt aatgaatgac gccacaggta ttagtgctgt tccatttaaa gaaaatacta
     1261 gtccagatga ttttgaggag agtatgaaag aaataattag tcagcatcat ttgcaacctc
     1321 taattatttt aacggattta attggaggaa cacctaataa tgtttctatt aaacagttga
     1381 acaacaatag aattcaaatt attgctggga ttaatttacc tcttttactg gagttattaa
     1441 tggcccagtc agctggtaaa tctatagaag aaatagattt taaggaatta ctgaataact
     1501 ctcaaaaaag tatggttcat attaattcgc ttttaaaaga tgtcagttaa ggtggcaatt
     1561 tctattctat aaattttaaa aattgaagga ggaaatagaa tgattaaatt agtgcgtgta
     1621 gaccacagat tacttcatgg acaagtaata ttttcttgga ctaaacagta tgatattaac
     1681 catattattg tggctgataa caaagttcca ggagatccaa tgtctgtgat ggctttgaca
     1741 attgctaaac ctgctgattg caaattagac attgttaaaa ttagtgatgt taaagggatt
     1801 atggaaacat ccccaaatga taattacatg attttaatta aaggacctaa ggaagctttt
     1861 gaattagttc aaaatttacc agaaattaaa gaaattaatt ttggcggtgt gtctaagaaa
     1921 agcgagtcca aacaatatgg aaaggcagtc tttttaactc ctgaagaatt agaagccaca
     1981 aaaaaaattc ttgatcaaga agtgaaaata tttgtgcaac aagtcccatc ttcaagtatt
     2041 gaaaatgtag attttagtaa gtaagggggg aaaataaatg ttattaaaag ccattttatt
     2101 aggtttagtt ggtgtggtag ctgttattga ctccaggtta attggtcgac aaaatattgg
     2161 tagaccacta attttgagta cacttgccgg acttgtgcta ggtgacttgc atacagggat
     2221 tgttcttggg gcatctttag aattaatttc tatgggattc gtctcaattg gggcggctgg
     2281 acctcctaat atgcaacttg gtagtattat tgccactgct tttgcaattt taactaatag
     2341 tagtacagaa acagccttaa caatagctat cccagtggct gtagctggtg aatttatgag
     2401 tattatcatg cgtatgataa ttgctcaatt tggacatgct gcagataaag ccattgaaaa
     2461 taataaattt agaaaagctc aaattattca tatttattgg tcatttattt ttaatgcttt
     2521 tgtttacttt attccaatct ttttaacagt atattttggt gctgacgttg tggcagattt
     2581 agtagataaa attccagaaa tgattacaga cgccttgact gtctctggaa atatgctttc
     2641 cgcattaggg tttgcaatgc tattaagcac aatgttgagt aaaaaattat atccttactt
     2701 tatttttgga ttctttattg ttgcctattc aggtctttca ctaattggcg tgacaatttt
     2761 tgcagctctg attgcctttg taatggatca agttaaatat ggaaaaagag aagaggcgca
     2821 tggttaatgg aaaatagtac agaaaaaaaa cgtttaatca caaaaaaaga tcttcataag
     2881 atgtgtcttc gttcatggac aatcatgtgt tcgtggaatt atgaaagaca aatgcatatg
     2941 ggatttatgt atgggatggc gccaatttta aataaagttt ataaaaatga tgaagagaaa
     3001 aaaagagaag cttatactcg tcatatggca ttttttaact gtacgcctca aatgactcca
     3061 tttattatgg gactttgtgc ttctatggaa gaacaaaatg ctcaagcaga agaaggaaac
     3121 tttaatactg aatctatctc catgattaaa accagtttaa tgggtccttt tgctggaatt
     3181 ggtgattcat ttttccaagg tactttaaga attattacat ttgggattgg attgtctttt
     3241 gctaagcaag gtagtatttt aggaccgatt ttagctgttg gcctttttgc tataccttct
     3301 attttagctg ttttttacgg cggtaaatta ggatatgagt ctggcaataa ataccttact
     3361 aaattgtatc aagaaggtct tatggatcga gtaatgcaat ttgcttctat cattggtttg
     3421 gctgtagtag gtggaatggt ggctagcatg gtgccaattg tcaccccttt aaaattcact
     3481 acagggggaa cagaacttgt tttacaagac ttacttgatt ccattattcc tggattatta
     3541 ccacttgtat gtactttggg aatatataaa ttgattaaga aaaatgttag tacaaatatg
     3601 ctcttattag gttgtatttt ggcagggttt gttttaagta taataggtat cttataatga
     3661 ttaaggctct aatttttgat atggacggag ttttaattga tagcgagatt atgtatcaaa
     3721 agtgggtatt taatttttta aaacaagaaa atttaagcta tcctttgtat tcttatcaaa
     3781 aaaagattgg aactacagca agtatttttg atgatataga aaagtacaat gagggatgta
     3841 acagtttaga attgaaggga aaatttacta aatattggaa atcgcaaaag attgattact
     3901 tggatatttt tcctaatata ctaattgaac agcttgaatg gttaaaaaag aaaaaaataa
     3961 aaatggcaat tgcttcttcc agtccaatgg atactataaa tgaagttgtt accacttgta
     4021 aaatagagtc atattttgat tgtttaatta gcggaagaga tttgccagaa agtaaaccta
     4081 atcctactat attccttaaa gcttcagaac agctcagaat tccagttgaa gaatgtctgg
     4141 tgatagaaga ttcttataat ggtataaaag ctggtaaaag agcaaatatg aaggttcttg
     4201 caattaaaga taaacgtttt tctcaagatg taagtctagc agatgatgtt atttacgata
     4261 ttaaatatct gcgacaagaa gtacaggtga aatttggaat ataaataagt tttttgatgt
     4321 atttagagaa tattagtaaa aataaaaatc atgcccaaat ctaatcaaaa ttgattgctt
     4381 tgggtatgat ttcttttaat atcaatctat tactttagga tctgaatcat ttttatgcac
     4441 cgtatctaaa gtgatatttt ctgtgacttc aataacataa ctaattctat cacaacgaac
     4501 tgtggattga gaataatgaa atggttgatt atttttatct ttgccaacct tttctaaaat
     4561 aaatagcgga tctcctacta tacattgcaa taagtcggaa agctcaggtg ttgcagataa
     4621 accgtttatt tccataatag agctcgtagc tttgacatca tagtcatctt ctagaagttt
     4681 atataatgaa gtatattggc tacctttttc aaataaagtt ggaaattttt cttctgatgc
     4741 gaaaaaatta tcaattccca tcggggcacc gtcttcccac attaaacgtt taatattgta
     4801 aactctatca gttacattga tttgtaattt attagctaaa aactcatcag cctttataat
     4861 tttagaatgt aaaacagtat atctaatttt atgtcctcgg gtagaaagag aatcgctaaa
     4921 tccatgaact ccagctaatt ttaaactttc ttttttttga gttacaaagg tccctttccc
     4981 ccttaatcgt tcaactgttc cactttctgt taaaagttta aaagcttttc gaatggtaat
     5041 cttacttact ccataaattt tacataattc ttcttctgta ggtaattgct ctcctggaag
     5101 atattttttt tcacgaatat cgttacgtat agaagcttct acttgtagat ataatggtct
     5161 attatcttga aaattcatag tacactccct aaaaagttat acttcattat atcacaattt
     5221 attaaaataa aagattaaga tataaatata aatgaactag tctttgacta accaatgccc
     5281 gcttttgaaa gaaaacaaat tcattctgtt ttaagtaaaa atccttatgt taccactcat
     5341 tctgaagggg atgagcctta tcgctacttg gttgtggaac caagcgataa gacaatttta
     5401 taaattcaat attaattaaa ataaaaacaa acaaagtaga ttattttact ttgtttgttt
     5461 ttttat
//
LOCUS       DACDLM010000124         5236 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.126, whole genome shotgun sequence.
ACCESSION   DACDLM010000124 DACDLM010000000
VERSION     DACDLM010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5236
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.126"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(1..1905)
                     /locus_tag="IV356_002782"
     CDS             complement(1..1905)
                     /locus_tag="IV356_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAP9016398.1"
                     /translation="MQQYILSKKNVITVISGLLIVLGFFSHFVLENVGLSEWSLIIAS
                     VFGITPIAIQAFQAMKVKVISIDVLVSIAAIGALFIQNYEESAIVTFLFLFGHYLEQR
                     TLNQTRSAIKELTDMAPESALVQTEDGEFEEVDVDDVDEGDVLLVKTGAKVPVDGTVL
                     TGEGHINEASITGESVPVTKTEGSEVFAGTILENGTIQIWADKVGEDTTFGKIIELVE
                     EAQDSKSEAERFIDRFSKWYTPTVLVLAFIVWAMTQNVELAITILVLGCPGALVIGVP
                     VSNVAGIGNGARNGVLLKGSEVINDFSKVDTIVFDKTGTLTVGNPEVAETEVYGDNVE
                     KAYSYLASVETESDHPLAKAVLQHTGTVELFPVEDTDVVKGGGVVAQVDGHRIAVGNV
                     ALMEKENVQLSKKAQKDVKQFEKNGNSLVLTAVDGELKILMGIRDQIRPGVKQDLQEL
                     KNLGVKDLVVLSGDNQGTVDRVARELNLTEAHGHMLPEDKAAYIEKLQQKGHTVAFVG
                     DGVNDSPSLALADIGIAMGSGTDVAIETSDVVLMNSNFSNLPHALGLVKATANNMKQN
                     IVISVGVVLVLLTSVFFSEWMNMSIGMLVHEGSILVVIFNGMRLMKYKLKGRKEQKEV
                     SAPAEKVKIY"
     gene            complement(2103..2336)
                     /locus_tag="IV356_002783"
     CDS             complement(2103..2336)
                     /locus_tag="IV356_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003106687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HAP9016399.1"
                     /translation="MEKAILQLETLSCPSCMQKIEGAVKSVNGVDKDSIKVLFNSSKV
                     KANFDSAVTSIEEIQKAIENVGYPVLKAKVKAA"
     gene            2575..3615
                     /locus_tag="IV356_002784"
     CDS             2575..3615
                     /locus_tag="IV356_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HAP9016400.1"
                     /translation="METERQIRELEKAMNTIDNRRLYERFLAVKLVLEGHTRKETGHT
                     IGRDEHTVSHYVKNYCHNGIQGLVSKKQSGRPSRLTDEQEAELVQIVAYHTPEEVGFK
                     SRANWTLAIVCDLILREWSYGYTQKGVADLLHRLGLSWTRPTYTLKKAGSKKQQVFLE
                     ETFPSLKKKLLNSDIDHLLFEDETMIRDYQAIGCTWFLRGHQRKIPTYGQHKGVKLIG
                     TLDYETGRIICTEEGAYDAAAFLRFLERTLREYPTGKIVMVLDNALIHHAKLIQSFLE
                     ENARRLALIFLPPYRPQLNLMEGVWKWLKESVINNVFFDHVQKIKQSVRGFLADVNER
                     PLEVIDRLCVRM"
     gene            complement(3930..4529)
                     /locus_tag="IV356_002785"
     CDS             complement(3930..4529)
                     /locus_tag="IV356_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP9016401.1"
                     /translation="MKSVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLSDVLEISRGRVIVKERLAMKEQKTAKHNSVFISNKLRKVILDYVQSEFLEQ
                     LQVQDFSKYLFPSRKGADTPLTRQSLWRIIHEAGTVVGLKEIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
BASE COUNT         1449 a         1190 c          980 g         1617 t
ORIGIN      
        1 ttaatatatt tttactttct ctgcaggtgc tgatacttct ttttgttctt tccgaccttt
       61 caacttatac ttcattaatc tcatgccatt gaaaattacc accaagatac taccttcatg
      121 aaccaacatt ccgatagaca tattcatcca ttcgctgaag aagacgctgg tcaacaagac
      181 caacactact ccaactgaaa tcacgatatt ttgtttcata ttatttgcgg tggcttttac
      241 taatcctaat gcgtggggca agttgctgaa gttcgagttc attaaaacga catcggatgt
      301 ttcaatcgct acgtccgttc cgcttcccat tgcaatcccg atatctgcta gcgccaagga
      361 cgggctgtca ttgacaccgt ccccgacaaa ggcgaccgtg tgcccttttt gctggagttt
      421 ttcaatataa gccgctttgt cttccggcag catatgcccg tgcgcctcgg tgaggttcag
      481 ttcacgcgca acccggtcca ctgtgccttg gttgtcgccg gaaagaacca ctaaatcttt
      541 cacgcctaaa ttcttcaatt cctgcaagtc ttgtttcact cctggacgga tttggtcgcg
      601 gattcccatc agaatcttca attccccgtc gactgctgtc aatactaagg agttcccatt
      661 tttctcgaat tgtttgacgt ctttctgcgc ttttttactc aactgcacat tttctttttc
      721 catcaacgcc acatttccaa ccgcgatgcg gtgtccgtcc acttgagcga caacgccgcc
      781 gcctttgacg acgtctgtgt cttctaccgg gaacagttct accgtgccgg tatgctggag
      841 gacggccttg gctagtggat ggtctgattc agtctccacg ctggctaaat aactgtaggc
      901 tttttctaca ttgtctccgt acacttctgt ttccgcgact tcaggattcc cgacagtcag
      961 cgttcctgtt ttgtcgaaca caatcgtatc aactttgctg aagtcattga tgacttcgct
     1021 tcctttcaaa agaactccat tgcgtgcacc gtttccgatt ccggctacgt tggagaccgg
     1081 aaccccaatg accaatgcac ctggacagcc taggactaag atcgtaatcg ccaattcaac
     1141 gttttgggtc attgcccaga caatgaatgc cagaaccaaa acagttgggg tataccattt
     1201 agaaaagcgg tcaataaagc gctctgcttc tgatttagaa tcttgcgctt cttccacaag
     1261 ttcaatgatt ttaccgaatg tggtgtcttc tccgactttg tctgcccaaa tctgaatggt
     1321 gccattttcc aatatcgtac cggcaaagac ttcactgcct tctgtttttg tgacaggaac
     1381 ggattctcct gtgatactgg cttcgttgat atgcccttca cccgtaagga ctgtaccatc
     1441 tactggaact ttcgcaccag ttttgacaag cagaacatct ccttcatcta catcatctac
     1501 atccacttct tcaaattctc cgtcttctgt ttggaccaag gcactttctg gtgccatgtc
     1561 ggttaattct ttgattgctg aacgtgtctg gttcaatgta cgctgttcca aataatgtcc
     1621 gaacaagaac aagaacgtaa cgatagccga ttcttcataa ttttgaataa aaagcgcacc
     1681 aatcgctgca atactgacta agacatcaat actgatgact ttgactttca ttgcttgaaa
     1741 cgcttgaatg gcaattggcg taatcccaaa gacagaggcg atgatcaaag accactctga
     1801 aagtcctacg ttttctaaaa caaagtgact gaagaaaccg agtacgatta acaatccact
     1861 gatgacggtg ataacatttt tcttgcttaa tatatattgt tgcatgcttt ttccctccaa
     1921 atttaatttc tcttttattg ataaacacag tataagataa ttgcctaagt aattaattga
     1981 ctgacatcaa gtttagaaag ttctctttta tcgtttctaa gcacctcgaa tcggattgca
     2041 acaaaaaaag caatcctgga aaaatagctt ttcttccaga attgcctagt tcatttaatc
     2101 tgttaagcgg ccttgacttt tgctttaagg accggatagc ctacgttttc gatagctttt
     2161 tgaatctctt caatcgaagt gacagctgaa tcaaaattgg ctttgacttt gctggagttg
     2221 aataatactt taatgctgtc tttatcaaca ccgttaactg attttacggc accttcaatt
     2281 ttttgcatac aacttggaca agacaacgtt tctaattgca atatagcttt ttccataatt
     2341 cctatctcct ttatgtgttt ttattttatc ggcagcagat taatgaacac tgccttttcc
     2401 tttttacaac tgtagtatag ctcactttta gcaaacgaaa attgacacat attaagtttt
     2461 gcacttcttt ttatcttttt gctcaattca ccatcttata caaattgagt taaattgtat
     2521 tcgtttttcc tcctataggc gtatactaaa gaaaacactt gaggagtggg gaacatggaa
     2581 acagaacgcc aaatccgtga attggaaaaa gcgatgaata cgatagacaa ccgccggttg
     2641 tacgagcgtt tcctggcagt caagttggtt cttgaaggcc acacccggaa agaaaccggg
     2701 cacaccatcg gccgcgacga gcatactgtc agccactatg tgaaaaacta ctgccataat
     2761 ggaatccaag gtttagtctc caaaaaacaa agcggacgac cttcacggct gacagatgaa
     2821 caggaagcgg aactggtcca aatcgtcgcc taccacactc cggaggaagt aggtttcaaa
     2881 tcccgtgcca attggacatt ggcgattgtg tgtgacctga ttctccggga atggagttat
     2941 ggatatacgc aaaaaggcgt ggcggacctc cttcaccggc taggactaag ctggacccgt
     3001 ccgacgtata ccctcaaaaa agcgggttcc aagaaacaac aggtattttt ggaagaaacc
     3061 ttcccgagcc taaaaaaaaa attgctgaat agcgatattg accacctcct attcgaggac
     3121 gaaaccatga tccgggatta ccaagccatt ggctgcacct ggtttctccg cggccaccag
     3181 cgaaaaatcc ccacttatgg acaacacaaa ggggtaaaat tgataggcac cttggattat
     3241 gaaaccggtc ggatcatttg tacagaagaa ggggcatacg acgcagcggc cttcctccgt
     3301 tttctggagc ggacgttgcg ggaatacccc accggaaaaa tcgtgatggt attggataat
     3361 gcccttatcc accacgccaa gctgatccag tcttttcttg aagaaaacgc taggcgcctg
     3421 gcactcatct tcctccctcc ctacagacct cagttgaacc taatggaagg cgtttggaag
     3481 tggctcaagg aatcggtcat caacaatgtt ttttttgacc acgtccagaa aatcaaacag
     3541 tcggtccgcg gtttcttagc cgatgtaaac gagcgtcccc ttgaggtgat tgaccgactg
     3601 tgcgtgcgga tgtaaagtat ttaattcaac ctatatagaa agaagtcttg tacttcattt
     3661 tagtctaatg acagtcataa catcatcgac agccccgtta ttgagtcaat tctattcaat
     3721 aatttcttct acttgtaata acgttgtatt caacgcttaa aatattccag cattaaacac
     3781 cagttccaca ctgttctttt tcaatagata caccgattct ttgcgagata attggtattt
     3841 atcaggagat ttaggacggt tttctacgtt cattttccca cctcttgaat ttttccttct
     3901 attatatagg tatatagggc gttattctgt catagatcca aactctttac tgcggtatct
     3961 ttgtcttcct gggtgatccc aatatagcgt aaggtttccc gttgtgaaga atggtttagt
     4021 agtgactgaa tgatctctgt tttggttcct tgcttgtaca aaaaatagcc aaaggtctta
     4081 cgcatcgaat ggggaccaat ttctttcaac ccaaccaccg ttcctgcttc atgaatgatc
     4141 cgccaaaggc tttgtcgggt caaaggcgta tctgctcctt ttcgacttgg aaacaaatac
     4201 ttgctgaagt cttgtacttg cagctgctca agaaattctg attgaacata atcaagaatc
     4261 acttttcgta atttgttcga aatgaaaacc gaattgtgtt tagctgtttt ttgttccttc
     4321 atggccagac gttctttgac gatcacccgg ccacgggaaa tttctaacac gtcacttaat
     4381 ttcaactgtc ttaaatcgga gattcgatac gccgtattga tcccgatcga aaaaagcacc
     4441 aaatttcgtt gcccatattt tccggaagcc aaaattgcct tcatggcgtc gatctttttt
     4501 ttatcgcgaa tcggttccac gctcttcatt tttagtcccc tctcaaatgt tacttaatat
     4561 gattataaca gataataagt cacatttaaa caagctatag aaaaaaggcc ctaaaagaaa
     4621 agtgatttcc tcttagagcc tctaaggatg gagcgatttt gatgaatgtg acagaatccg
     4681 attgtgtcac attaggcttt tgatattttc ggtaagattt gattatctca gaacattaat
     4741 attgcccctt taaaaaattt tgtcagtact tttaagttat tctattctga aaattcaaaa
     4801 ttttcagtct atataattaa cttatattca gttttaccaa atgataagct ttaaaaagta
     4861 ttcagaattt agtcatgtta tggatccaat aaagtagata tggaatattt attttctctt
     4921 gtctaattta taagaatatg atttgtcaaa gaattaaagc tatgaattat tcagcctgaa
     4981 taattcatac ttttaattaa aaccatgtga aactgcctca cggcagctta caattacttt
     5041 ttcatcttca cccgttaagt gatgaaaaaa gaaccccttt ctactatggt taaagtgact
     5101 aaaccaacca aaagaaagga gttcttttca tgactagctt acacaaaaac caagtaaaat
     5161 tcaattcaaa tatcactatt tctcatacag gtggtcaatt atcgagtgat tcgggtctcg
     5221 tcctagtgaa agagct
//
LOCUS       DACDLM010000125         5005 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.127, whole genome shotgun sequence.
ACCESSION   DACDLM010000125 DACDLM010000000
VERSION     DACDLM010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5005
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.127"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            52..261
                     /locus_tag="IV356_002786"
     CDS             52..261
                     /locus_tag="IV356_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAP9016402.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMVSKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            254..403
                     /locus_tag="IV356_002787"
     CDS             254..403
                     /locus_tag="IV356_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HAP9016403.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            438..1222
                     /locus_tag="IV356_002788"
                     /pseudo
     CDS             438..1222
                     /locus_tag="IV356_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922412.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(1506..2591)
                     /gene="xerS"
                     /locus_tag="IV356_002789"
     CDS             complement(1506..2591)
                     /gene="xerS"
                     /locus_tag="IV356_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HAP9016404.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            2925..3158
                     /locus_tag="IV356_002790"
     CDS             2925..3158
                     /locus_tag="IV356_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HAP9016405.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            3155..3562
                     /locus_tag="IV356_002791"
     CDS             3155..3562
                     /locus_tag="IV356_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HAP9016406.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(4013..4522)
                     /locus_tag="IV356_002792"
     CDS             complement(4013..4522)
                     /locus_tag="IV356_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016407.1"
                     /translation="MKKVLFAVSLVVNIALAGGLFYTITEMNKLDDQRESLAISNEQY
                     KRKLDEASSTNVDTQEAVESSTIVYSNESSETLTNSERSTAPATETVSQKATITIGSK
                     VFTFIVNGLTIEHDSSRTGKMTELSHEFPVIVTTPSATLNGILVQDNNDNNCYIMVDG
                     QTLYRGTYQ"
     gene            4638..5005
                     /locus_tag="IV356_002793"
                     /pseudo
     CDS             4638..5005
                     /locus_tag="IV356_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1727 a          730 c          866 g         1682 t
ORIGIN      
        1 tatttttagt agtgttcttt tttatatttg aataaaaaat gtggtggtta aatggtggtt
       61 ataacaaaaa atgaattaat gaaattaggt tatgggaagt atcagtctga gagaatcata
      121 cgacaggcaa aagcaattat ggtttcaaaa agctatacct attacgaaaa tagaagatta
      181 ggactagtac ctgttgaatc tgtagaagaa gttttaggta tgaagataga ggtagaggag
      241 gattttcaga atcatggtta attttaaaaa agataaaaat gggaaatatc attttactgc
      301 tagtttggga ttcgacaaac gaacagggaa aagagtacaa aaaaacgtag aggggttaaa
      361 acagttaaag aagaaaaaaa gcgtataccg aacttgtttc taattatgga aaagaagcag
      421 aaacttctca aagtactatg ttgtttgagg agttttttta taaattattc ctaccttatt
      481 atcaagggaa agtagaagaa agaacatata aaaatcggtt atctacaatc aaaaaaactt
      541 ttcttatttc tttaaaatgg agttaagaga aatacgtcca attgacattc aaaagtggca
      601 aaataattta ttgagcaaat ataaaaattc ttatgtaaga aacatgtatg ggatttttca
      661 gatgtcatta gatcgagcag ttgttttggg actacttgaa aaaaatcctg caaaagttat
      721 tggaaatgtg aagaaaagga aaactacagt tgatttttgg acaaaagaag aatttacaaa
      781 agttatttca actttttata ttgatgattt gtaccaacat tttggtttta tttgtatgtg
      841 gttacttttt atgaccgtta tgcgtttggg agaagccact gcattaactt ggaaagatat
      901 tgattttgaa aataaaaact tgcgtgtgaa taaaacactc tattataaga gagccaaaac
      961 ctatgagttt gtagaacccg aaacggcttc tagtattcgt acaatcgaac tagacgacaa
     1021 tacaattacc tttttaaaag cttggaagga gcgtcaagtt tcaataggag gcatgtcgtt
     1081 tgtactttct tataatggaa cacctactca gaaatataca atccgtcata ttatgagaag
     1141 acatgcaacg atcgttggtg ttcatataat ccgcatacac ggattaaggc atagtcatgc
     1201 ttctttgctt atatcacaat aaaaagatgc acttcgaatt aaagaaaggt taaaacatgc
     1261 tgatgtacaa acgactttag gaacttatgg tcatttgtat ctaaattcat tgagagagat
     1321 aacaaatgat cccacagatt atatccaaac taatttttct aaaatcaaac cgacacctat
     1381 ttacgataat aaaaaataaa tgataaacaa aagtaggatc acaccaaaag aaacacacta
     1441 gaaaaactat aatacaggct tttctagcgt gttgtttctt atttccgcct atttatacat
     1501 tatactcata aagcatttaa tgcatcgatc gtagccgcat tgtctatatg ggtatataaa
     1561 gttgttgtat tggtacttga atgtcccaat tgttgggcag ttaataccaa tgaatttgtc
     1621 tgttggtaga gtctagtagc taatgtatga cgcagtttgt gagggctgac ttgaattcta
     1681 aagccttttg aatattttgc taccatccgt tcgattgcaa taccggatat acgcttggct
     1741 tctccttggt aaattgctag aaataaagct ttttcgtttt ctgttacttt atatcgttct
     1801 ttccgaatag ctagataatt agctaaatat tccattgcga atgctgctat attgacagca
     1861 tctcttttat ttccttttct agttactacc acattattct tatctaaaga taggtcatct
     1921 aaattaatat ttataacctc ggagagtctc aatccagatc ctaaaatcag tgcattgatc
     1981 gccaggtctc tttctacatc tcgttgataa tagatcaaag ctcgtttact caaagtattt
     2041 ttatattcat tggcaatata atctagataa ttttgtgtat ccttatctag aaataatttt
     2101 ttctcaatgg cattggcacg tgcagctaac gtagttttat ctgtgatggt tgctacttga
     2161 tccataggat tattgtctaa gtatggtttt cctagaggat tattggaact tttcgaaaga
     2221 tatttaaata gaacctttaa tgccgtgata tttctattga tagtagaagt agatagacct
     2281 aagttattat tatctttgag cttagttttt gttgtctctt tttttacatt ttcttttgtg
     2341 cgacgtttca aatgagattt gtacaagttt aggtcatagg cagttaactg tcttatcgag
     2401 gtgatagaag tatcaggaac gatagactca ctcagaagcc attcataaaa gagcttataa
     2461 ttttttagat attctaaagt ggttcgaggt gattgatctt tatcctcacg atcttgaaca
     2521 aaatctttta tataatcggg catatgaagt atgattgtat ctattttttg atatatttct
     2581 gtatttttca tgtcattcat cctttcaata agtaggggag aagagtatct ctataattgg
     2641 actataccaa ttatagaatg ttttgtcaat tggtatgctc taaaatttat taatttgttt
     2701 caaaaaaagc atataaacag gtatacgttt aataatttaa aataaatggt atacataaat
     2761 agggaaggaa atagaaggga gcaatctaaa ttttttgaat tttcttaatt aattatatag
     2821 aaagaacaat ctttctatag agttagacat gagagggact atgcttgatt taaaatcaac
     2881 aagcgtatat actgtatata caaagaaaaa ggagggagaa gactatggca attaaagaaa
     2941 gaaaatttag ggaagtgggg aactcagtag tattaactat ttcaaaggag tttcttaaag
     3001 aaaatgggtt aaatcccgga gatacggttt ttttagatga agaaaaactt cgagcggcaa
     3061 ttacaaaaaa acaagcctta tctgatgaaa ttgatttagc aatatctcaa gcattaactg
     3121 aatatgatac tacttttaga gagcttgtcg ataaatgagt attcattacc tagaagccaa
     3181 agatattata aaaatgaatg taatccaaat aaaaaaatac tctcctaatg aaccccttgg
     3241 tgtaaaggat gcgaatgctt tagaaatgtg tgtagggcaa cttcgagcct cagcttttgg
     3301 tgaagaggtt tatccttcga tttatgaaaa agcagctatc ctacttatac aattgataaa
     3361 gaaacatcct tttcacaatg caaataaacg tactgctttc ttagctactt ttgtcttttt
     3421 gaaaatcaat ggacagcttt tagctattga tcaaaaagat gctgtaaatt tagcggtata
     3481 tattgctacg tatgataagg atttcgatca actaaaatat gaagtgatca acactataaa
     3541 gacacatacg cagcccattt aaggagttac tgtatgtgtc tttatagggt tattagctgc
     3601 tatagcgaaa taattgaagt aaattacaaa tagctataat tcaaatccaa ctatatagaa
     3661 aacgtaaatt ttctatatac ttggatatgc tggaatgttt aagagaataa ttacatttct
     3721 agaaaataca ataaaaatta caggataatt agccatatcc tacctcctct agcagttgct
     3781 caaaagttag cactaagtaa cttctttttt gttgctggta acaatttatc aatactaaaa
     3841 tagcgtttaa gtatctaata aatactaatt ttaaagctct taattattat gaaacacgat
     3901 ataacaatat tgctatatcg tgctattgta atattataca tttgaagaca gcgtattctt
     3961 gttctaatat caggaatttt ttataaatat cagtcatatt aagactcaaa atttattggt
     4021 atgttcctct gtatagagtt tgaccgtcta ccattatata gcaattatta tcattgttgt
     4081 cttgcaccaa tataccgtta agggtagcac taggagtagt aacaatcact ggaaactcat
     4141 gagaaagctc ggtcattttt cctgttctgc tagaatcgtg ttctattgtc aagccattta
     4201 ctataaacgt gaatacttta cttcctattg ttatagtagc tttttgagaa acagtttctg
     4261 tagctggagc tgtgcttctt tccgaatttg ttagggtttc actggattca ttgctataaa
     4321 caattgtaga ggattctacg gcttcttgag tgtccacgtt ggtgctgcta gcttcatcta
     4381 gcttcctttt gtattgttcg ttactgattg ctaagctttc ccgttggtca tcaagcttat
     4441 tcatttctgt aatggtataa aataatcctc ctgctagtgc tatattaaca actaaactaa
     4501 ccgcaaataa tacctttttc attcttcctt ctcttctttc tctttttgta attccttact
     4561 tttggatagg ctacaattaa ctagacagaa aaattaaggt gtgtagacta gaagaaaaca
     4621 taccaggagg aatttttatg tctaagagaa cacgaagaac tttttcacaa gaattcaagc
     4681 aacaaatcgt caatctttac ttagatggaa agccacgtgt agaaatcatt cgagaatatg
     4741 aactaacggc ttcagcattt gacaaatggg taaagcaatc taaaacgagt ggttcattca
     4801 aagaaaaaga taatcttacg cctgaacaaa aagaattgtt agaactacgt aaaagaaacc
     4861 agcaattaga aatggaaaat gatattttaa agcaagcagc gctgatattc ggacgaagag
     4921 acaagtaatc gatgcgaata agcatcttta ccctatatca gcgatgtgca gaatattagg
     4981 tctatcacgt cagtcctatt attat
//
LOCUS       DACDLM010000126         5004 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.128, whole genome shotgun sequence.
ACCESSION   DACDLM010000126 DACDLM010000000
VERSION     DACDLM010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5004
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.128"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            109..477
                     /locus_tag="IV356_002794"
                     /pseudo
     CDS             109..477
                     /locus_tag="IV356_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347492.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            577..777
                     /locus_tag="IV356_002795"
     CDS             577..777
                     /locus_tag="IV356_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016408.1"
                     /translation="MLKRIAWDKDNKTVIELKEYKYNYFSRCIDRKLLFKKEGLEFSF
                     DEDEFEKLVMDWRKNLLDTVQF"
     gene            911..2137
                     /locus_tag="IV356_002796"
     CDS             911..2137
                     /locus_tag="IV356_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016409.1"
                     /translation="MIFYMFININEVLKMTTITMTKNIEVYVDGSQEERDSFFDFFWK
                     NSREYVKALNLVYKQLMFEELIKDAIKEMDQGYAEREESIQNRIEKLAYTDPIDQKKL
                     DKAKAELSKLRNEKNKEAREILTQAIGLKSQTRTRDVAKKLDFDFGDFVDSANMKASK
                     DFGNDFIGIVTGQRTPRIYRNKSKYGLLPFRGRDIKIHKADKFYISLPKGFRLKVNLG
                     SKPRKARDVASVLQHIMDGDYKLNQSNLIFDGRKLFFNLTISFEKSYNEMEFKKGNEL
                     IVNFADLCSGECLINDKSVMSFGDSQYIRNFKSKILAMKSKEQSRGVFSKGGHGRKRK
                     LDQDRWEAIKKRESNFVKTYNNQCSAKIVKTAIRNKAQIIRIIEPDKAYGEWAYYQLK
                     EQLVNKGKRYGIEVRS"
     gene            3062..4387
                     /locus_tag="IV356_002797"
     CDS             3062..4387
                     /locus_tag="IV356_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAP9016410.1"
                     /translation="MFDYSREPVNDYFLIDMKSFYASVECIERNLDPMTTPLIVMSRS
                     DNTGSGLTLASSPTAKKKYHITNVSRANDLPYPLPKELYIVPPRMNLYIKKNMEVNQI
                     FRKYVADEDLLIYSIDESILKVTKSLNLFTSSETRSERRRELAKIIKDEIEKETGLIA
                     TVGIGDNPLLAKLALDNEAKSSKEFIAEWTYETVPEKIWKINEMTDFWGIGSRMKKRL
                     NHMGIMSIEDLANWNPYTIKSQLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPKDYTRREEVELVVKEMAEQVAIRIRQHNCKTGCVRLAIGTSILEEKSGFSHQMKI
                     PITDNTKELQNYCLFLFNKFYEGQEVRHIGVTYSRLVYTDSLQLDLFSDPRKKIAEEN
                     LDRIIDKIRQKYGFTAIIHASSMLEGARSITRSTLIGGHAGGLGGLHND"
     gene            4380..4727
                     /locus_tag="IV356_002798"
     CDS             4380..4727
                     /locus_tag="IV356_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016411.1"
                     /translation="MIEYNDRGRLKWSGFYLSDHTERINADNVQRANHNLAKEQMTTE
                     EIAKILRTAVIKNRPVCIQKEERNAEGYYPDDVVGKIIGYDELGVFVEEEKVHYDEIR
                     NVSFAELLKWSQI"
BASE COUNT         1942 a          614 c          944 g         1504 t
ORIGIN      
        1 tcatgtgaat atgaacttaa caattaaacg tatttacgat cttttatcac ttatataaag
       61 agagaagtga taaataggac acaaaatttg gaaagtaggt aagtcactat gagagaacta
      121 actttatctt ctgaggaatt agaaaagaaa actgctttat taaacgaaat atttagtgct
      181 gattgtataa tccaaagttt aaaagaaagt tcattttcaa aactaacaga tcagaaaaaa
      241 atttcttata tgctaagttt agataatcta ggaactaaat atgatgaatc ggcaagtagc
      301 gataagcttt tgattgaatt agtatcaagt cttagtagtt ttggaaaaat gaaaagattt
      361 aatgtgatat tagaaatttt tgcttggata atcccttcat ttatttggtt tttttatatt
      421 ttcatagttg aatctgagtt aatagccaag gtctctcttg aactgttaat tccgatatat
      481 gcattttatt taataggttc agcaatttac tttaataact tgtatacacg tattcaaata
      541 aaaaagcagt tattacatga aggattaagt ggtaatatgt taaaaagaat tgcatgggat
      601 aaagataata aaacagttat tgagcttaaa gaatataaat acaattattt ctcgagatgt
      661 atagatagaa agttactgtt taaaaaagaa ggattagaat ttagttttga tgaagatgaa
      721 tttgaaaaat tagtgatgga ctggcgtaag aatttactgg atacggtaca attctaaaag
      781 caattgaggt cgaaattgcg atacttgaat catggtctat attatcgtgt tatgagtgaa
      841 atttctaata aagataagat atttcatttg gacagtcatg tgaatatgag cttaacaatt
      901 aaacgtattt atgatctttt atatgtttat aaacattaat gaggtgctaa aaatgacaac
      961 aataactatg acaaaaaata tagaagtata tgttgatgga tcacaagaag aaagggattc
     1021 cttttttgat tttttttgga aaaatagtag agaatatgta aaagcgttga atctggtata
     1081 taaacagcta atgtttgaag agttgataaa agatgcaatt aaagaaatgg atcaaggtta
     1141 tgctgagaga gaagaaagta ttcaaaatcg gattgaaaag ttagcatata ctgatccaat
     1201 agatcaaaaa aaacttgata aagcaaaagc tgaattatct aaattgagaa atgaaaaaaa
     1261 taaagaagcg agagaaatat taacgcaagc gatagggttg aagagtcaaa cgagaacacg
     1321 agatgtagca aaaaaattag actttgactt tggagatttt gttgattcag caaatatgaa
     1381 agctagtaag gattttggca atgattttat tggaattgtt actggtcaaa gaacacctag
     1441 aatctataga aataaaagta aatacggatt gttaccgttc agaggtcggg atattaagat
     1501 tcacaaagct gacaagtttt atatctcttt acctaaagga tttagactta aagtaaattt
     1561 aggtagcaag ccaagaaaag caagagatgt tgcttcagtt ttacaacaca ttatggatgg
     1621 cgattacaaa ttaaatcaaa gtaatcttat ttttgatgga agaaaattat tttttaatct
     1681 aacaatttct tttgaaaaaa gctataatga aatggaattc aagaaaggta atgaattgat
     1741 cgtaaacttt gcagatttgt gtagcggtga atgtttaatt aatgataaat ctgtaatgtc
     1801 ttttggtgat agccaatata taagaaactt caaaagtaaa attttagcaa tgaaatcaaa
     1861 agaacaaagc cgaggagtct tttctaaggg cggtcatggt cgaaaaagaa aattagatca
     1921 agatcgatgg gaagcaataa agaaaagaga aagtaacttt gttaaaactt ataataatca
     1981 atgttctgca aaaatcgtta aaactgctat tcgcaataaa gctcaaatta ttcgtatcat
     2041 tgaaccagat aaggcttatg gcgaatgggc ttactatcaa ttgaaagaac aactagtaaa
     2101 caaaggaaaa agatatggga tagaagtcag aagttagtaa tttaaacaat cgttgatttg
     2161 gcaacgaaat agtgagggaa aatccactca ctgaagggta aactccgtca agttgtgtga
     2221 ccagacggaa ggacgaatgt tgttgaggtt ttagaactat ataaaacagc atgtttctca
     2281 aattatgaga tgttaagaaa aatgattcga gaggttttag aactatataa aacagcatgt
     2341 ttctcaaaca aagtgcagaa cgaaaatcaa ttcatcacag ttttagaact atataaaaca
     2401 gcatggtttt aaaacaagaa ataagtcagt tttccttttg ctttagtaag gaaaaataga
     2461 gtattctcaa taaaacttaa aataagaaag aataagcaaa cctttgtttt aatagctaat
     2521 cgaagtaaaa cccaaagcca tatgaactcc tgaatcagcg aaagtttatg atgattgggc
     2581 ttactaataa tttaggaatt agatggtaaa tctaaattaa acaatcgttg atttggcaac
     2641 gaaatagtga gggaaaatcc actcactgaa gggtaaactc cgtcaagttg tgtgaccaga
     2701 cggaaggacg aatgttgttg aggtttagaa ccacataaaa cagcatgttt ctcaaattgc
     2761 cttagtggtt gaattgagat ctatcacgtt ttagaaccat ataaaacaac atagttctca
     2821 aattgtttaa aatgattgtc aagttaaaaa aatctgggat catataaaat agtatagttc
     2881 tcaaatatga ttagaaaccc tattaaagag caatattaaa ccaacttact taaatcgttt
     2941 aattaagaac agtaatctct tttagtcaga cttttagtct gacttttttg tatttccaaa
     3001 atttattctt tacaaaagcg aacgtacgtt tgtataattg cttgtgaatg ggggaataaa
     3061 aatgtttgat tacagtagag aaccggtgaa tgactatttt ttaatcgaca tgaagtcttt
     3121 ctatgctagc gtggaatgta ttgaacgaaa tttagaccca atgactacac cgttaattgt
     3181 catgagtaga tcggataaca ctggttcagg tctgactcta gcttcttcac ctactgcaaa
     3241 gaaaaaatat catatcacta atgttagtag agctaatgat ttaccttatc cattaccaaa
     3301 agaactttat attgttccac ctcgaatgaa cttatatata aaaaaaaata tggaagttaa
     3361 tcagattttt agaaagtatg tcgcagatga agatttattg atttattcga ttgatgaatc
     3421 aattttaaaa gtgacaaaat ccttaaattt atttactagt tcagaaacaa gaagcgagag
     3481 gagaagagaa ttagctaaaa taatcaaaga tgagattgag aaagaaacag gactaatagc
     3541 aacagtcgga ataggagaca acccattatt agctaaactc gcactggaca atgaagcgaa
     3601 gagtagtaaa gaatttatag ctgagtggac ttatgagact gtacctgaaa aaatatggaa
     3661 aataaacgag atgactgact tttggggcat tggatcacgc atgaaaaaaa gattgaatca
     3721 tatgggaatt atgagtatag aagatttagc aaattggaat ccctacacaa ttaaaagtca
     3781 gttaggtgta atcggacttc agttatattt ccatgccaat ggaattgatc gtacggatat
     3841 tgctattcca ccagaaccaa ccaaagaaaa gtcttatggg aattcacaag ttctaccaaa
     3901 agattatacg aggagagaag aagtagaact agtagtcaag gagatggcag agcaagtagc
     3961 cattcgaatt agacaacata attgcaaaac tggttgtgta cgcttagcaa ttggtacgtc
     4021 aattttggaa gaaaaatcag gtttctccca ccagatgaaa ataccaatta cagataatac
     4081 gaaagaatta caaaattatt gtcttttttt attcaataag ttttatgagg ggcaggaagt
     4141 aagacatata ggagtaactt atagcagatt agtatacaca gattccctac aattagattt
     4201 atttagtgat ccaagaaaaa agattgctga agaaaatttg gataggatta ttgataagat
     4261 tagacaaaaa tatggattta cagctattat acatgcttca tctatgttag aaggtgcaag
     4321 aagtattacg agaagcactt taataggagg acacgcagga ggattaggag gtttgcataa
     4381 tgattgaata taacgataga ggacgtttaa aatggtcggg attttatttg tctgatcata
     4441 ctgaaagaat caatgcagac aatgtacaac gtgctaatca taatttggca aaagaacaaa
     4501 tgacgactga agagattgcg aaaatactga gaactgctgt cataaaaaat agacccgtct
     4561 gcattcaaaa agaggaacga aacgctgaag gttactatcc agatgatgta gtaggaaaaa
     4621 ttattggata tgacgagctt ggtgtatttg tggaagaaga aaaagttcac tatgatgaaa
     4681 ttaggaatgt ttctttcgcg gaattattaa aatggagtca gatatgaaca ttattaaaaa
     4741 atacgaattc ggttatatta cgtatgaaca gctaatagag gaattatggg gatatggtca
     4801 acaattaatt aatgaagtgg ggattgattg cttttgtttc tatattgaat ccggagcagg
     4861 ataccataag aacagatact atatatttcc atatccacca aaatagtctc ttagagattt
     4921 ttaaattttc tccaaatact ttcaattatt gtgaaatatt tccctttaac agaattaggc
     4981 agaagtcgcc catcctctat aggt
//
LOCUS       DACDLM010000127         4772 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.129, whole genome shotgun sequence.
ACCESSION   DACDLM010000127 DACDLM010000000
VERSION     DACDLM010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4772
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.129"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            1..369
                     /locus_tag="IV356_002799"
     CDS             1..369
                     /locus_tag="IV356_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAP9016412.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            549..1490
                     /locus_tag="IV356_002800"
     CDS             549..1490
                     /locus_tag="IV356_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HAP9016413.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1559..2290
                     /locus_tag="IV356_002801"
     CDS             1559..2290
                     /locus_tag="IV356_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HAP9016414.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2434..4614
                     /locus_tag="IV356_002802"
     CDS             2434..4614
                     /locus_tag="IV356_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HAP9016415.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4634..>4772
                     /locus_tag="IV356_002803"
     CDS             4634..>4772
                     /locus_tag="IV356_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HAP9016416.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HL"
BASE COUNT         1595 a          847 c         1067 g         1263 t
ORIGIN      
        1 atgtttacga atgaaataaa aatcatgctt tatgtggacg atgtagaaaa aaatgcaacg
       61 ttttggagag cagttggctt tgcggaaaaa gatcgtcaag aaatggatgg gacgcttata
      121 attgaagtag gagttgagga cagtcaaacc tcatttctgt tatatgatcg agcatttgtt
      181 gagtcccatt cacctggcac agctactagt gccccatctt tgatgtttta cagtaaagat
      241 atctttggac tatataaaaa aatgcagacg caatcagtca cattaggtga tatggtacag
      301 cttggagaag aatatgtctt taactttgct gatcccgatg gcaactactt tgcggttaca
      361 ggtaaataat agaaataaag actttgtttt tctgtgcgaa acaggaaagc gaagtctttt
      421 taattcaaat aataatatta tgtaaacaaa aaactttcca tgcgtaatta tacacaagca
      481 aataaatcgt caaatgcgaa cgccttcttt atactgttta ggaacgaaaa gaaggaagga
      541 agaaatacat ggattatcaa gtactgcttt attacaatta tacaaaaatc gaagaaccag
      601 aggaatttgc caaaaatcat ttagcctttt gcaaatcttt ggatcttaaa ggtcgtattc
      661 tagtagctga agaaggaata aatggtactg tgtctggaac cgttgaaaac acgactgcct
      721 atatgaaagc aatgaaagct gatcctcgat ttgctgatac gatgttcaag atcgatccaa
      781 gcgaaggaca tgcctttaag aagatgtttg taagataccg tccagagctt gtaagtttaa
      841 agctagaaga ggacattgat ccaaaccaag tgacaggtgc ctatctttca ccgcaagaat
      901 ttaaagaagc tattttagat gaacagacag tggtgattga tgcacggaat gattatgaat
      961 atgacttggg acattttcga ggggctgtac gcccagatat acgcagtttt cgagagcttc
     1021 cagactggat ccgcgagcac aaagaagaat ttatggaaaa acgggtagtg acctactgta
     1081 ctggtggcat tcgttgcgag aagttttctg gttggcttgt ccgtgaagga ttcaaagatg
     1141 tcggacagct gcatggcggt attgctactt atggtaagga tcctgaagtc caaggagaat
     1201 tatgggacgg caagatgtat gtgtttgatg aacggatcgc tgtcgatatc aaccaagtag
     1261 ataaacaaat cgtcggtcgc gactggtttg acggaacacc atgtgaacga tatatcaatt
     1321 gtagcaatcc tgagtgcaat cgtcagattc ttgcttccat tgaaaatgaa gaaaaacatt
     1381 taggagcatg tagcatagag tgtgcgaaac atccgcgcaa tcgctatgtt caagaccatg
     1441 gaatctctcc agaagaagca gaactgcggt ttacagcttt aattaaatag aaaacaatag
     1501 ttttgattgt cgaccatttc caatatgcgc tatactagcg ttgaggatgg tgatccacat
     1561 gaaatcattg atttatgcta ttggggatgt ccatggcaaa catgagcttt ttgaaaaact
     1621 tattcactat tatgatccaa agatccatca gcttgtttta ttaggggatc tcaatgatcg
     1681 aggtcctcgt acaaaagaat gttttttatt aggaaagcaa ttagtcgaag aaacaggagc
     1741 catttacctc cggggaaacc atgaagaata ttttttgcaa tttctgcaat caccggagga
     1801 ctggtatgcg ccttatatga gaaatggtgg aaaagaaacg tttgaaagcc tgattcaccc
     1861 aggggcatcg gaggaatact ccccaactga aatctcgatg atgatccaat cgagatattc
     1921 agaactgatt aaatttttag tccagcgccc cttgtattat gaatgggaaa attatctttt
     1981 tgtccatgcc ggtgtggatt tgacaaagaa agactggcgt aagacaagtc taagagactt
     2041 tatttggata agggaaccat ttcatgaagg gaaaaacaat acaggtaaga caattgtatt
     2101 tggacatacg attacaccaa tgctccatgg agatatgcag acaacagacc tctggattca
     2161 ggatcataaa atcggaatgg acggtggggc tgtattcgga gggtcattgc atggggttgt
     2221 ttttgacaag gaaggtattc ttcaagatat tgaatatcag aacaacgaag gaccttggca
     2281 tggaatctga ctaatggaaa gaatgaagga gctgtgactt tgttgcggct ctttttattt
     2341 ttatagagaa tattgtttct ttcagtagtt taacccagga taaaaagtat gatagaataa
     2401 agaagcaatt tttagcagaa aagaggcatt ttaatgacgg aaaatttgaa ccagacgatc
     2461 attcagcttg tacaaaaaga actttcagac tatcgtccta agcagttgac tactgtactt
     2521 aatttgttaa atgaaggaaa cactgttcct tttatcgcgc gttaccgaaa agaaatgact
     2581 ggaagtcttg atgaagtcca gattcgtgaa atcgaagagc ggtatgccta tcttgaaaac
     2641 ttagaaaaac gtaaaactga agtgattcgg ctaatcgatg aacaagggaa actgactccc
     2701 gagttagaag cagaaatcac ccaagccgtg aaaatgcaac aagtggaaga tttgtatcgt
     2761 ccatacaaac aaaaacgacg gacaaaagca acgattgcta aagaaaaagg acttgaacca
     2821 ctcgcgaagt ggctgatgca gcttacagat ggagaggtgc aatctgaagc agaaaaatat
     2881 attgacaaag aaaaagaagt ctcttctgcc gaagaagcgt tgcacggtgc tcatgagatt
     2941 attgctgaac aagtcagcga taatgcaaaa tttcggactt ggattcggtc ttatacgtat
     3001 aacaaaggta tgtatgtcag caatgtcaag gatgagcaag cagatgaaaa aggcgtatat
     3061 gaaatgtatt atgactttgc agaacccgtc cataaaatgg tttctcatcg aatattagct
     3121 actaatcgtg gagaaaaaga agatattctg aaagtattct ttcaagtaga tgaagcagca
     3181 attttagctt acttggatcg ccaaatagtc aaaaatcctg cctctccttc ttcttcattc
     3241 gtcagagaag cctatcagga tagttataaa cgctttattc agccagcaat cgagcgagaa
     3301 ctgcgcaatg aattgactga aaaggcagat gagcaagcaa tcgctatttt cggcgaaaac
     3361 ctccgtaatc ttttgttgca accgccacta aaaggtaaag ttgtcctggg atttgatccg
     3421 gcttatcgta ctggatgtaa actagcagtc gtagatgcga cagggaaagt tttagcaatc
     3481 gaagttattt atcctcataa acctgcagcg caagcaaaaa gagaagctgc tggaccagct
     3541 tttatccaat taattaataa atatcaagta gatatggtag ctatcggaaa tggtacagcc
     3601 agtcgggaat ctgaactttt tgtggctgag cagttgaaat ccgccgacca taaaacctat
     3661 tacgctatcg tcaacgaagc aggcgcttct gtttactccg ctagcgaaat tgcacgaaaa
     3721 gaatttccgc atctacaagt tgaagaaaga agtgctgttt ctattgcccg tcgcctgcaa
     3781 gatcctttag ctgaattagt caaaatcgat cctaaagctg tcggagtagg ccagtaccaa
     3841 catgacgttt ctcaaaaacg tttggctgaa caattggatt ttgttgtgga aacagcggtt
     3901 aaccaagtag gtgtggatgt gaatacagca agcccgcagc tcttgcagca tatatcagga
     3961 ttgaataaaa caactgccca aaacattgtc atttatcgtg aagaaaacgg agaattcacc
     4021 gcacgaactc aattgaaaaa agtgccacgc ttaggaccaa aagcatatga acaagcaatc
     4081 ggattcttgc gagtccctgg tgggaaaaac attttggaca acacaggtat ccatcccgaa
     4141 agttattcta ttgcaaaaga aatattaact tcagtccaac tttcagaaaa agagcttggt
     4201 acagaagaag cagtagaaaa attgacacga ttatccgtag agaaactggc tgaaagccta
     4261 tcagtcggag aagaaacgtt agccgatatt ttagctgggc tgacacaacc tggacgagat
     4321 atgcgtgatg agatgccagc gcccttatta cgtacagatg tattgagtat ggaagacttg
     4381 aaaccaggga tggaattgac tggaacggtc cgtaatgtca ttgacttcgg cgcatttgtt
     4441 gatatcggtg tgaagcaaga cggacttgtc catatatcga aactcagcaa aaaattcgtc
     4501 aagcatccta cagatgtcgt gtcagtagga gatatcgtaa cagtttggat agaacaagtc
     4561 gatacgaaaa aaggcagaat cagtttgacg atgctttccc cttatgaaga gtaacaatga
     4621 ggagtaacaa aaattgacac aagaagaact gcagcagtta gtagaagaga tatcattaaa
     4681 aagcttccag cttcctttca agcaccaagc aatgttcaat ccacgcttac gtacaactgg
     4741 cgggcgctat catttaaacg atcatcattt ag
//
LOCUS       DACDLM010000128         4681 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.130, whole genome shotgun sequence.
ACCESSION   DACDLM010000128 DACDLM010000000
VERSION     DACDLM010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4681)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4681)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4681
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.130"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            59..913
                     /locus_tag="IV356_002804"
     CDS             59..913
                     /locus_tag="IV356_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP9016417.1"
                     /translation="MENSIYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1010..3259
                     /locus_tag="IV356_002805"
     CDS             1010..3259
                     /locus_tag="IV356_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAP9016418.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKIPEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3262..4437
                     /locus_tag="IV356_002806"
     CDS             3262..4437
                     /locus_tag="IV356_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP9016419.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTRVTRGAS"
     gene            complement(4440..>4681)
                     /locus_tag="IV356_002807"
     CDS             complement(4440..>4681)
                     /locus_tag="IV356_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAP9016420.1"
                     /translation="PPRKNMDKSEKLDHSLLGKQRKTVETVFSSLEKLGCQNFNSRSV
                     KGLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT         1633 a          675 c          850 g         1523 t
ORIGIN      
        1 gtaataatat aaacataata aaacaaaaat tatccaaatc taacatagga gggtggatat
       61 ggaaaattct atatatttag taacagaacc taacactcag ctgaaagatt gttactttaa
      121 tttttgtggg tattcaaaaa cagaacctag acatagtttt ggaccagcta ttcgagaaca
      181 atacttaata cacatagtgc tagaaggtga aggctattat tcaattaatg atcaaaaata
      241 ttttctgaag aaaggccaag gatttgttat cccaccagga gtatctactt tttatcaagc
      301 agatgaaaaa aatccgtggt catatgtatg gttgggttta agtggcaatc ttgtagaata
      361 ctatctaaaa gaaattggtg ttggaaagaa tcatcttacc tttaaagtcg aaaatttaaa
      421 ttcatttaaa ggattaattt ttgaaacttt atcgtatgat caggacaatc tagtcagtga
      481 attgtccaga caaaaacaag tttataaatt tttagaactc ctcttaaatt cagctagtta
      541 tctgaacgaa gggataatta ctaaaaagat gaatcctttt gttcgtcaaa caattgaaat
      601 aatacgtgag aatgcgtatc aaaaattatc tgttaaagat attgctgtca gtctatcgat
      661 acacgaaaat tatttatcac gattgtttaa gaatgatatg ggaatatcaa taaaagagta
      721 tattagtgaa atcaaaattt ctattgcaaa cgatctgtta tcatcaactg aatattcaat
      781 ccagcaaatc agtgacaaga taggattctc aacagtacaa tctttttcta aagcctttaa
      841 gaaagcaaat ggtgtttcac cgggagtata tcgaaaacgt agattaggtc taggaatcat
      901 taatggtgaa taaactaaac atttgatttt gataaatatt cgttacttta aacgcttact
      961 atttatgtga gcgtttttta taatgcaata aagaaacgga ggagagctta tgtataagga
     1021 taatgaaatg aatattattt atcgatcaga aaaccaacaa tttcatttgt ttaatcagga
     1081 gataagttac atttttaaga taccggaaga tggtaaatta ttgcatttat attatggtga
     1141 gaacttacca gataatgact atagtcatct aattgagatg catcatcggc ctatgacaac
     1201 ctatagaaat gaaaacgatt tgctatattc gttagagcac ttaaaacaag aatttcctga
     1261 atatggtaca acagatttta gacatcctgc tatttcatta ctacagaaaa atggctctcg
     1321 cttatcagat tttgtctatc aagggtacga agtggaagaa ggaaaaccta aactagaagg
     1381 tttacctgct acctatgttg ataataatga tgaaagcaaa acattgaaag tttatatttt
     1441 agattcagtt acaaatgttc aagtagaatt attatataca atttatagag attatcctgt
     1501 tattactcgt agcgcgcgag ttatgaataa aggaaaagat attcaaataa tcgagaatat
     1561 tagcagttta tcattggatt tacccgatgc aaattatgaa tggcaacaat tatctggtgc
     1621 ttggggtaga gaaagaacta ttaagtcgcg tactttacaa caaggaattc aatcaatcga
     1681 atctactcga ggtatttcaa gccatcagca taacccattt gttactttaa aaagaaaaaa
     1741 tactgatgaa aatcaaggag aagctattgg tgcagcacta gtttactcag gaaacttctt
     1801 aattcaagca gaagtagata catgggatgt tactagacta caagttggca tcaatccatt
     1861 tggatttaat tggaaactca atccaggaga aatatttaca gcaccagaag cgattctggt
     1921 ttattcaagt aagggtttaa atgccatgag tcaaactttt catcaactat ttagaaaacg
     1981 cttagctcgt ggtaagtggc gagaaaaaga ccgtcctgtc ttaattaata attgggaagc
     2041 aacatatttt gattttgacg aagaaaagtt ggtaaatatt gctaaaaaag catttgatgt
     2101 tggtattgaa ttatttgtat tagatgatgg ctggtttgga gaaagagaaa acgattgtgc
     2161 aggattagga gattggcatg taaatcctaa aagactacct agaggaatcg gcagcctttc
     2221 agaaaaaatt cgtagttttg gtatgaaatt tggtttatgg tttgaacctg aaatggtgaa
     2281 taaggatagt gagttatatc gcacacatcc gaattggatt atttctacac ctaatcgaaa
     2341 acctaatcat ggtaggaacc aatatgtatt aaattttggg ttagatgagg ttgttgaaaa
     2401 tattttcgat caaatgtgta aaatcattga tgaatcaaac ttagattaca ttaagtggga
     2461 tatgaatcgt ccattgactg atgtatttga cagtcacttg tcagcagatc aacaaggaga
     2521 agtattccac agatatgtac taggcgtata tcgcttatat gaaaaactta taacaaaata
     2581 tcctaacata ctatttgagt cttgttcatc aggtggtggg cgctttgatc ctggaatgct
     2641 tcactatgca cctcaagctt gggctagtga tgattcagat gcaattgaaa ggttaaaaat
     2701 tcaatatgga actagtatgc tgtatcctct ttcgtctatt ggtgctcatg tatcaattgt
     2761 tccaaatcat caaacaaacc gtataacacc tataaaaact agaggaaatg tagctttttt
     2821 tggtgcattt ggatatgagc ttgacttaaa tgaattaagt gaaggcgatt tgaggattgt
     2881 aaaagaacaa attgcctttt ataaaaaata tagaaccata attcataatg gtacttttta
     2941 tagactatta tcaccattcg atgatgataa tcaaaccgcg tggatggttg ttagtcatga
     3001 taagaaaacg gctattgttg ctcattataa aacattaaat gaggtaaatg ctccttaccg
     3061 ccgactgaaa ttaaaagggt tagataatga cggactttat aatgtaggac aaaatagttt
     3121 gcgatctgga atggaattga tgagagcagg actagtctgt tcagatgcat ctagtggaca
     3181 aataaatgat cagaatcgac gcccagaaac atttgatttt gattccaaga tttgggttat
     3241 aacacaggag gaaaagtaga gatgaataac caaaaaagct tacttcaaaa aggagcaatc
     3301 ttaagtattt cactaatgtt aacaagctct caagcaatta atggtgttat tccacaaatg
     3361 aaacagtctt tggggatatc acaaagtcaa agtgaacttt taggaactgc accaagtata
     3421 actgttattt tgtttatctt attatctagt tactttgcca aaagaatagg aatgaaaaag
     3481 acaataattt taggtttatt attagctggt ataggaggaa ttattccagt atttacagct
     3541 accttccaaa ccgttcttat tagtcgagta atattaggtg ccggtttagg agtatataat
     3601 tcattggctg tgacatatat cagctcttta tactctggca atactagagc aacgctatta
     3661 ggtattagaa attcaatgga agctttaggt cagacaatcc ttatttttct tgctggagtt
     3721 ttagtgaaca ttaattggac ggcttcgttt ttagtctatg caattgcgtt tcctgtagct
     3781 ctcttattcg cgctaaaagt tcctgaaatt agagatgaaa atagtgacat acctgaaaat
     3841 catgtaaaag aaaagatgaa tccaatggtt tttgccctag ttctatttgc aatcttactc
     3901 gtaatgaata gtattgctat ttctgtacga tttgcatcaa ttgcaactga aattaaaggg
     3961 gtaaacttta atgctagtaa ctatttagct ctaatgccta tcttaggaat actagcagga
     4021 tttatgtttg gaccaataaa taagtggata ggaaaaggaa ccctatactt gggaattata
     4081 ttctttataa tttcaaattt gttaattgct gtgtcaaacg gtaatatgac gttcctgcta
     4141 acgggtttat ttttatcaag tataacagga tcatggtgct tcccatttat ctttagtaac
     4201 ttagataaag tcactacaaa gaatacaatt aattttgcta cttcattgat ttttattggc
     4261 tgtaatattg gtaattttat agctcctatt gctatgcaat tagcacaatt tctaacaaga
     4321 agtacaaatt tgactgctcc attttttgta ttcgcaggaa tatttattgt gatcctattt
     4381 gtaacatttt ttgcgacaaa taaaaaaaat actagagtaa cccgtggtgc tagttaattt
     4441 taatatccta aagaatatct caaagttcct tcaaaacgtc gttgtgctcg acttaataga
     4501 acactgtaag ccagtaatat gctttcaaat ctactctcta gccctttaac agaacgtgag
     4561 ttgaaatttt gacaacctaa tttttctaag gaagaaaaaa cagtctcaac tgtttttctt
     4621 tgttttccaa gtaagctgtg gtctagtttt tctgatttat ccatgttttt acgtggcgga
     4681 a
//
LOCUS       DACDLM010000129         4430 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.131, whole genome shotgun sequence.
ACCESSION   DACDLM010000129 DACDLM010000000
VERSION     DACDLM010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.131"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(543..2048)
                     /locus_tag="IV356_002808"
     CDS             complement(543..2048)
                     /locus_tag="IV356_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP9016421.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="IV356_002809"
     CDS             complement(2045..2731)
                     /locus_tag="IV356_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP9016422.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="IV356_002810"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="IV356_002810"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HAP9016423.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1238 a          919 c          729 g         1544 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat
//
LOCUS       DACDLM010000130         4424 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.132, whole genome shotgun sequence.
ACCESSION   DACDLM010000130 DACDLM010000000
VERSION     DACDLM010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.132"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            690..1658
                     /locus_tag="IV356_002811"
     CDS             690..1658
                     /locus_tag="IV356_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP9016424.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADVRNHDLDVRRYMGKVEY"
     gene            1669..2484
                     /locus_tag="IV356_002812"
     CDS             1669..2484
                     /locus_tag="IV356_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HAP9016425.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKEIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            2552..3262
                     /locus_tag="IV356_002813"
     CDS             2552..3262
                     /locus_tag="IV356_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP9016426.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYIMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            3298..>4424
                     /locus_tag="IV356_002814"
     CDS             3298..>4424
                     /locus_tag="IV356_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HAP9016427.1"
                     /translation="MKQILRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIK"
BASE COUNT         1490 a          661 c          921 g         1352 t
ORIGIN      
        1 atacaaataa ttcaccaaaa aggtgagtaa tgccattttt gaaaattgag cttgttttat
       61 gtctacatct gtatccgtat ataatccaaa ggattataaa ctcagaagag tctttatttt
      121 ttctgaatat aactactgta tcaaaaacaa tcgattatga gacaaaacaa aatgacctct
      181 tttatttaag aaaggaggtc attttttgta tcataaattg tattaaaatc aatgtatcac
      241 tttttaatca gttttaagac cataaattgc gtactaaaag aaattctgca attcaaaata
      301 aagcatttta agccattttc aaatttaagt gcacccatct acccgtcaaa tcactttatt
      361 ttccactcca gtagtttcct aattcaactg tgtgcaaaaa cgatttcttc taaacaaatc
      421 aagacaaact tataaacctt catcccagca ccataattat ttaaatcata ggcatttttc
      481 gaaattagta tatgtactca agtttcactg cagattattt atatttttta gagaaataaa
      541 tttttcctat tgacaaacac aaagaaagcg gatacaatgc aattatgtca catgacgtta
      601 tatgacgtta tgtgatatct ttacatttaa tcagttactt ttattttgga taaaattaac
      661 atttttaaaa ttttaaggag gaaatgttga tggatgtagc aaaaacggtt aacgcaattg
      721 tagaaaaaaa tgatggagag atttctggaa tttatttggt ggcttgtggc ggttcgctgg
      781 tagatatgta tgtctcagat tattttctta aagccgaagc atcgaagtgt attacaggct
      841 tatatacagc gaacgaattt aaccatgtaa ccccaaagca attagatgat aaatctgttg
      901 tcattctatg ttctcatgga ggaaatacag cagaaacggt aaaagcagga gaagtcgctc
      961 aagctagagg agctgtgact gttggtctga ctcataataa aactgcggat ttattaaagg
     1021 tttctgatca tagtttcctt tacgaatggg gagatgatgc aaaaatagtc aataatccta
     1081 tggccatcat tcttgattta actgtatctt tggtcaatgt taccgaaaca tttgaacatt
     1141 acggtaaatt cagagaaggc atgaaggtta tcgataccgt aattgaaaat ggcattaagc
     1201 aggtgcagga tcgtattaaa gtgtttgctg ataagtacaa agatgaaaca atgttttata
     1261 tcttaggtag tggaccatca tatggacatg cttatggttt ttcaatttgc tctttgatgg
     1321 aaatgcaatg gcttgattca acttctgttc attctggaga attcttccat ggaccttttg
     1381 aagtaacaga caaagatacg aattttattc tcttgatgag cattggacgc actcgtgctt
     1441 tagatgaacg ggcaaaacga ttccttgata aatatgcaga aagagtagaa atcgttgatg
     1501 caaaggaact aggattggat atgatatcag atgaagtttc tgaattcttc aatcccattt
     1561 tattctacag tattctttca gaatatcgtt cagctttagc agatgtacgc aatcatgatt
     1621 tagatgttcg tcgctatatg gggaaagtgg agtactagga ggattaaaat gaaggtatta
     1681 ggcttaggtg ataacgtcgt cgataaatat gaaaatctgg gaattatgta tcctggagga
     1741 aattcattga attttgcagt ttttgcaaaa aaactgggac atgaaagtag ctttatggga
     1801 gtttttggct cagatgagga ggcagctcat gttttatcag caataaaaga aataggactg
     1861 gacaacagtc actctcgctt tgaaaaaggc gagaatggct gtgccagagt gaagattgat
     1921 gagggcgacc ggattttcct tggcagcaat tcgggaggtg ttactcgtga atacccgatt
     1981 cagcttactg aagaagacag agaatattta aaccagtttg aattgattca tatgggatta
     2041 tatagccatg tcaatcatct attagaagag ttacaaaatg tttctggaaa gatttcttat
     2101 gatttttctg acgactttac ggaagaagag gttcagcggg caattgataa agttgatttt
     2161 ggcttctttt ctatagaaga cttttccgat gaagaagtaa agcagttttt gatgaagcat
     2221 ttttgtgagc gaaatgatgt attgattgca acccgaggag aaaaaacggc tattggttat
     2281 gatggagcaa agttttatga agtgaacccc gtgctagaag aaccagttga tacaatggca
     2341 gcgggagatt ctttcttaac agctttccta ctttattttc tcgaagggga cgatatagtc
     2401 accgcgatga aaaaggggaa tgaatttgct gggaagtctt gtctggttga cggttcgttc
     2461 ggctttggta ttcattacga ttgagcttgt tttaaattcc tgcatttgat aacctaaaga
     2521 aagaaatccc ggtaaagtgg aggttaaaaa aatgctggat acaaatgcac aattaccatt
     2581 gtacttacaa ttaaaagaaa tattaaaaaa taaaatcaat acaggggagt atcccgagaa
     2641 tacgaaaatt cccgctgaat cagagctgat agaaagttat gaggtcagcc gaatcacagt
     2701 gagaaaagca gtagaagaac tggtagaaga agggtaccta cttaaaaaac aagggaaagg
     2761 aacttttgtc aaccggcata aagtttttcg taaaattgaa tatattatgg gtttcagtga
     2821 gagttgtaaa tctaatggtt ttacaccgac tagcattgtt ttggaacgca agatcattcc
     2881 agcaactgaa gggatggcaa aaaaactcga tatcgctcaa ggtgatgatg ttttatatat
     2941 ccagagaaag cgaatggcgg ataacatccc cattatgtta gaaaacaatt atttttctta
     3001 tgaaagatat agtttcttaa tggaggaaga gctgactgat tctttgtatg aagtacttaa
     3061 agtccaaggt accttagcca tcaatcctgg ggaaactgca cttgaaattg tcacagctga
     3121 tgaccaaatt gccaaaataa tggaagtagc tgttgggacg ccctttttct ttatggatac
     3181 tttaatcaac gatcaaaaca acataccaat tcatgtaggt aatcaatatt acctgggaga
     3241 agtatatcgt ttttacttat gatttcctgt ttggatttca aggagtagat tttatttatg
     3301 aagcaaatat tgcggtcaaa aatgattttt gatggagagc agccaccttt caaaggttat
     3361 attgtaatca atgaagggat cattgaaaag gtggaaaaca actggaatta cagtgatcta
     3421 ttaaatgaaa acacggaatt aattgcttat gatgatcaat tcgttatgcc agcaattcat
     3481 gataatcatg tatttttcag tggttatttg gctatgaatg ctggcataga tttaagcgat
     3541 acatcttcag ctaacgaggc tgtagagcgt attaaagctg taatgaacca taaaaaagca
     3601 gatgaaccaa tttatgctca tggctgggat gctgccctgt ggaaaactga cccatcagaa
     3661 gagctattga atgaaataaa ccactttggt ccaatcacag cgatcgacaa aaatcgcagc
     3721 cattgttgga tgaatgctat tgctaagcag acttatggtt ttacagaaaa agaaaccagt
     3781 gctgaaagtc gagtattatt aattaaggaa atgctagcaa acaaaaagct tttagcagag
     3841 gtttacgctg aatttgaagc attactgctt tcaaaaggtg ttatatcaat gaaagaaatc
     3901 gtttttgatg acgcagaatt tctttctaat atacctcaga ggaaaatact tagtaaccta
     3961 tatgtgcagg cagtccaaga acctctacag catgaacttc tatatgagta taaggaaaaa
     4021 gttttccctg aaaaggtccg ctttggtgga gtgaagatca tggtagatgg tgttgttgcg
     4081 gatagaagtg gagatattta cggtgtttat cagtcaggag tagcttcacc cgagattgac
     4141 tatgaggcaa ttaaagcaga agttgctgca ttcaatgaag tagagattcc ttgctgtttg
     4201 acaacggaag gagataaagc gggttataaa gctgcgtcaa ttcttgtcga atttggaaag
     4261 cggttacctg aaggcgtttt taattcgatt agtgatttgg aaatggttac tcaaaagaca
     4321 gcagaaaaaa tgaacgaagg acaagtagta gcagaggtat atccacaaat tctcggcttg
     4381 aatcaaacgt tagaagaggc ttacatgtca actgttataa aaaa
//
LOCUS       DACDLM010000131         4422 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.133, whole genome shotgun sequence.
ACCESSION   DACDLM010000131 DACDLM010000000
VERSION     DACDLM010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4422
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.133"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(166..1467)
                     /locus_tag="IV356_002815"
     CDS             complement(166..1467)
                     /locus_tag="IV356_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005227456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP9016428.1"
                     /translation="MENSAFIMKLNDILSPIAAKIGNQRHLKAISSGMMFGLPFIVIG
                     SFFLIFANPPINIDKYNPDTANIFMKFMASWKDFAVANYDLITAPYNLTMGIIGFISV
                     FGIAFSLANEYKINPSMNGMVASVIYLMVCTPVEEGAINLNFLGTNGLFVAIIIGLLV
                     VEINRLFEVKNIKLKLPDTVPPMVATFINMLVPLLTNIFIFYGINLIFLAATNKIFPE
                     AVMEVLTPATNIAGSLGGFLLIVTLGNILWLFGINGSSIIFPIVFTLGMAQTGLNAEQ
                     LANGETMTHLMNLQMFRISVLGGAGGTLGLVLLMMRSKVPEYRTIGKLSLVPGICSIN
                     EPVIFGLPIVFNPILAIPFLITPIISLLLTYFAQQLGWIGIGFIVDPSFTPFFAQAYL
                     SSMDWRNILFCLLLIVISIFIYYPFFKVMESNKTKLVDEKL"
     gene            complement(1479..2096)
                     /locus_tag="IV356_002816"
     CDS             complement(1479..2096)
                     /locus_tag="IV356_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016429.1"
                     /translation="MTETKFIQDPWSKMTTRNGLRGDEAISALQKSIRRGKEKEACEF
                     AYEMYITSPQFEEKLWRRLLAISVEDVGMGNPMAAIMINNLNAMRKEFQYNESDRAMY
                     FFHAIRYLCQSEKDRSSDLLKNIVIKSFAMGYIPEIPDIALDKHTVRGQAMGRGSEHF
                     LHEASKVIPQAKVDNDYKEQYEKIIETYDPDHVVPSTFSFNPWQV"
     gene            2137..2829
                     /locus_tag="IV356_002817"
     CDS             2137..2829
                     /locus_tag="IV356_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005470391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP9016430.1"
                     /translation="MDVEMLIDKYQLNDSEAEVLRFMKKNRQSLKNIGIRDVAKASYV
                     STATIINMAKKIGYSGYSELVFALGNSQSDITMPSTFSNEEKEAFIHLMSAYRDKRIM
                     ILGSGFSQNLANYFSESLNLYGFRATANSHLEFLRQQVQQDILLFIISNSGDTVRLAE
                     LAKIANDHFIDVIAFVGQKNSKIGTLATLTISTETYIPQKISDYQPNLFFGTTLNQFE
                     LLLSAALKAIYK"
     gene            complement(3263..>4422)
                     /locus_tag="IV356_002818"
     CDS             complement(3263..>4422)
                     /locus_tag="IV356_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /protein_id="HAP9016431.1"
                     /translation="ERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLD
                     RKELASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFG
                     HQEQTDYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNH
                     SLPNTDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWE
                     EREVQYFSTTYQAQSWSQSRHVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSLYA
                     KRGTMENFIKEAKAGVYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGM
                     TIHSIRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRGSQWI"
BASE COUNT         1382 a          823 c          853 g         1364 t
ORIGIN      
        1 aaaaataaag gaagtagcct tttgaacaag ggcgcttcct ttatttgttg tgggacacca
       61 gagtatactt ttttataaaa aataggttga tgggaaaccc taagatttcc catcaacact
      121 aaatagtata gaaccatatt ttcgttacaa ggttaagaat gacgactata gtttttcatc
      181 tactaatttt gttttattgc tctccatgac tttaaaaaat ggatagtaga tgaagatgct
      241 gatgacgatc aacagtaggc aaaagagaat attgcgccag tccatacttg aaagataagc
      301 ttgtgcaaaa aaaggtgtga aggaaggatc gacgataaat ccaatcccaa tccatcctag
      361 ttgctgagca aagtaggtca gcaataatga aatgatgggc gtaatcaaaa atggaattgc
      421 caaaataggg ttaaaaacga taggtaatcc gaaaatcact ggttcgttga tggaacagat
      481 tccaggaacc aatgacaatt ttccaattgt gcgatattcg ggtactttgc ttcgcatcat
      541 caataaaacc aaacccaaag taccaccggc tccaccaagt acagaaatac ggaacatttg
      601 taagttcatt aagtgtgtca tggtttcacc atttgccagt tgttcagcat tcaaaccagt
      661 ttgagccatt cccaatgtaa agacgatagg gaaaataatt gacgagccat tgataccaaa
      721 tagccatagg atgttaccca aagtcacgat caataagaaa ccacctagac tgccagcgat
      781 gttcgttgct ggagtcagga cttccatcac cgcttcaggg aagattttgt ttgttgctgc
      841 caagaaaatc agattgatgc cataaaagat gaatatattt gtcagcagtg gaacgagcat
      901 attgataaag gttgctacca tgggtggaac tgtatctggg agtttcaact taatattttt
      961 tacttcaaat agtcggttga tttccactac tagcaagccg atgataattg cgacgaacaa
     1021 tccgtttgtc ccaaggaaat taagattgat ggcaccttct tccactggtg tacaaaccat
     1081 tagataaatg acagatgcaa ccatgccatt catggaagga ttaattttgt attcattggc
     1141 aagggaaaat gcaatgccaa aaacactaat gaatccgatg attcccattg tcaaattata
     1201 aggggctgtg atgagatcat aatttgctac ggcaaaatct ttccagctgg ccataaattt
     1261 catgaaaata ttagctgtat ctggattgta tttatcaata ttgatgggtg gatttgcaaa
     1321 aatcagaaaa aaagaaccga taacaataaa gggtaggcca aacatcatac cgctggatat
     1381 agcttttagg tggcgctgat tacctatctt ggctgcgatg gggctaagta tgtcattcag
     1441 tttcatgata aacgcagaat tttccatata acttcctcct atacttgcca aggattaaat
     1501 gaaaacgtac ttggcacgac gtgatctgga tcataggtct cgatgatttt ttcgtattgt
     1561 tccttgtagt cattatcaac ttttgcttgg gggatcactt tacttgcttc atgcaaaaag
     1621 tgttctgaac cacgccccat tgcctgtccc cgaacagtat gtttatccaa cgcaatatca
     1681 ggaatttctg gaatatatcc catagcgaaa ctcttgataa caatgttctt aagtaaatcc
     1741 gatgaacgat ctttttcaga ttggcatagg taacgaatcg cgtggaaaaa atacatcgca
     1801 cgatcggatt cattgtattg gaattctttg cgcatggcgt ttaagttatt gatcatgatg
     1861 gcggccatag gattgcccat gcccacatcc tcaacactga tcgccaatag ccttctccag
     1921 agtttctctt caaattgtgg tgaggtgata tacatttcat aagcaaattc acatgcttct
     1981 ttttcttttc ctcgacgaat cgatttctgt aatgctgaga tagcttcatc tccacgtaag
     2041 ccgttacggg tagtcatttt tgaccacgga tcttgaataa atttcgtttc tgtcataata
     2101 taatactcct attagataaa atttgaggtg aatcttatgg atgttgaaat gcttatagat
     2161 aaataccaac tgaatgactc agaagctgaa gtcttacgat ttatgaaaaa aaatcgtcag
     2221 tctttaaaaa atattgggat tcgtgacgtt gccaaagcat cgtatgtttc tactgcaacg
     2281 attatcaata tggcgaagaa aattggatat tccggttata gtgagttggt atttgctcta
     2341 ggaaacagcc aatctgacat tacgatgcca agcacattct ccaatgagga gaaggaagca
     2401 ttcatacatt taatgtctgc gtatcgcgat aaacggatta tgattcttgg ctcaggtttt
     2461 tcgcaaaatc tagccaatta tttttcggaa tctcttaatc tatatggatt tcgtgcgacg
     2521 gccaatagtc atttagaatt tcttagacag caagtgcaac aagatattct gctttttatt
     2581 atttccaatt ctggtgatac agttcgatta gccgaattag ctaaaattgc gaacgatcac
     2641 tttatcgatg tgatcgcatt tgttgggcaa aaaaattcaa aaatcggtac gctggcaaca
     2701 ttaaccatta gcacggaaac ctatattcca caaaaaatat ctgattacca accaaatctt
     2761 ttctttggca cgacactgaa tcaatttgag cttttgttga gcgcggcgct gaaggctatt
     2821 tataaataga agaacgctgt ggccactgtt tcttcaaaat ctagtataaa gaatcttctt
     2881 tagaatgtaa ttgttttctg tgtgttctga acatgtttag gaatttccaa acttgtttag
     2941 aaaactttct cattccctcc gctgtagaat tgaactcaca taaaaaacat ctaaaccaaa
     3001 atatctacaa gcttggaaag gataataggt tgttattaaa aataattttt attcctgaac
     3061 ctgaataatt catagcttta attctttggc acattttatt gaaatatgta tcactaatat
     3121 ccctatcaac tgattttgac taaaaagtta cttcaaacat tcactgttca aaaatattga
     3181 ggaataaatt ttgggtgtaa ggcattttga gcatacttct ccctggataa cttcccagta
     3241 aaaaaatcgt tagattgttg gattagatcc attgactgcc tcgcctcagg cgagcaaaga
     3301 ccctgtagaa ttcattctga tacacatgat aactagataa tttgagatag actcgtctac
     3361 ccgtttggac taatttccca gcaactttca gaaacttcaa tcgaatagaa tgaatggtca
     3421 ttcccttttg gacttcttca aagccaatcg ttcttaagaa gttgactaag ttgtaagcta
     3481 tcaagctgag catcattcgg acatgattct ccaaaaagcg aggactgtct gttttgtcaa
     3541 agtaaacgcc agctttcgct tctttaatga agttctccat tgtgccacgt ttggcataga
     3601 gagaaaagat ggtatcagga gaaacatttt ctgatagatt cgtcacgata aattcatgtc
     3661 gaaagagtag ttcgcccgct tcacgtgttg agcgtataca cacgtgacga ctttgtgacc
     3721 aggattgtgc ttgataagtg gtcgagaagt actgaacttc tcgttcttcc cacttttgat
     3781 tatcgccata aagtactgat ttctcagcga tttgacctag tctacgatta ttcttcagtc
     3841 gaataacata atgactcttt tttgattcac acgaatcata cacaccaggt gtagcgaacc
     3901 cgctgtctcc acgaaccaag atgtcagtgt ttggtagaga gtgattatag tgctctaata
     3961 aaggtgtgag aaactccttt acgccttttg atgtatattg atttcctgaa cgtagttcag
     4021 cttttaagaa gtcaccagtc aatccgtcaa aagctaccaa tggatggtaa ccataggttt
     4081 ggtagtgtgt attataatcc gtttgttctt ggtgaccaaa tgtatctgaa tgggtcgaat
     4141 ctaaatcaat gattaattcc gtatcattac ggatgaggcg tgctttatcg ataagttctt
     4201 ggttcaaagc ttgaagttca tggatattct cctcagatag tcgatctaaa aatcgggaaa
     4261 gtgaagattg agaagcgagt tctttcctat ctaaaacagc tttaaacaca ggatcttgtc
     4321 tcaggagatt agctgcagaa tcagctgagt aaccagcaat taattgcata atgaactgct
     4381 caagtatgga taagttgtca tgagtaaaat acgctcgttc gt
//
LOCUS       DACDLM010000132         4388 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.134, whole genome shotgun sequence.
ACCESSION   DACDLM010000132 DACDLM010000000
VERSION     DACDLM010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4388
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.134"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            85..972
                     /locus_tag="IV356_002819"
     CDS             85..972
                     /locus_tag="IV356_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP9016432.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="IV356_002820"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="IV356_002820"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HAP9016433.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="IV356_002821"
     CDS             2274..2720
                     /locus_tag="IV356_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAP9016434.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="IV356_002822"
     CDS             2993..4345
                     /locus_tag="IV356_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase"
                     /protein_id="HAP9016435.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
BASE COUNT         1499 a          727 c          931 g         1231 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctt
//
LOCUS       DACDLM010000133         4310 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.135, whole genome shotgun sequence.
ACCESSION   DACDLM010000133 DACDLM010000000
VERSION     DACDLM010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4310
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.135"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(65..1285)
                     /locus_tag="IV356_002823"
     CDS             complement(65..1285)
                     /locus_tag="IV356_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAP9016436.1"
                     /translation="MKLIGIVGSAAELSYNRKLLTFIQKQYHELFNLEIIEIKDLPLF
                     NQDDDQTNSPAIQQLNRKILMADGVIIATPEHNHTVPAGLKSALEWLSFKIHPLENKP
                     VMVVGASYYDQGTSRAQLHLRQILDAPGVNALVMPGNEFLLGKAKEAFDQEDRLIDPR
                     TVDFLGSTLASFVKFIKVVSTLAGPKKLPPEDLHATGTIATTIPDVDMSDDHWLEKAS
                     EAVGAVSGNTYVKLNRGLLTVDQINYFLDSMPMELTFADNNNQFLYYNLRQEAKEMLA
                     ARVPGQVGNPLANCHPEKSYKNVEWVIQQLRSGATDAVRVHVPKQVPEKYIVHNYQAM
                     HDENGEYAGINEYILDFKPIIEWYLQQTGQQLVGNEDAVSSASVHGGKTDAVTSASTH
                     DETAVDAVSSASVK"
     gene            complement(1305..1910)
                     /locus_tag="IV356_002824"
     CDS             complement(1305..1910)
                     /locus_tag="IV356_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005234653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAP9016437.1"
                     /translation="MKFIGLVGTNSTRSTNRELLQFMKNYFVNEAEIEIVEIKELPLF
                     NKPENTELPNVVKEIAGKIEQADGVIISTPEYDHAVPASLINALNWLSYGIFPFVDKP
                     VMITGASYGTLGSSRAQAHLRQILDSPELKARIMPSSEFLLGHSLQAFDEQGRLIDEE
                     QVAKLRELFKDFLLFVTITSQLQHAHQANKREAESFSWETI"
     gene            complement(1959..2891)
                     /locus_tag="IV356_002825"
     CDS             complement(1959..2891)
                     /locus_tag="IV356_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HAP9016438.1"
                     /translation="MNQVIEETKIWQMMGTTITLQVGHEEPSRLLAELGEWLHVYEHR
                     FSAHDATSELMAINQAAGRQAVIVHPELFELIKLGKAHSCARNSYLNIAIGPVVQKWH
                     IGFEDALVPTKAEITELLLLTDPHQIQLDEKMKTVFLTKPGMMIDLGALAKGYIADKL
                     ITHCRERNAAFALVNLGGNIVVFGESPRRSDGAWRIGLRNPKGSREESLAVVKLNNQS
                     LVTSGIYERYLQNGSSVYHHIIDPKTGFPVKNDVASLTILSDSSVDGEIWTTRLFGAS
                     SLEVLKALEEQPGIEGAVVTKENQFLYTKGFEKI"
     gene            complement(3312..4172)
                     /locus_tag="IV356_002826"
     CDS             complement(3312..4172)
                     /locus_tag="IV356_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP9016439.1"
                     /translation="MNIEKFITARKAANLSQKEVSEGICTQATLSKFENNGQVPSLKI
                     LIKLCNRINLPLVELFSSMNVINTQLDEQLEKAEFSLITSEYEQLTQILAAIDPKVID
                     ESELIARYYYLKGFEMIFTNAPITDVLFHFDQLLMAETANTLFRLLAYTGIGMVYARE
                     KELEKAEVYFNRVFEKIYTYPIRTTEDIWRVLNIVFHCGVFFAQDGDLETSDALLNYA
                     IDICSDNHLTYYLARAAAQLAKNAQAKNKSKAEVLELIQDALAFAKINKNKKLIDELN
                     HMKKMILLIN"
BASE COUNT         1230 a          866 c          707 g         1507 t
ORIGIN      
        1 agcttaaatc atagataccg taagggactt tattctttat ttaaaacttt gcaacagaac
       61 ctttttattt tacagaagca ctcgaaactg catctactgc agtttcatcg tgtgtgctgg
      121 cgctggttac tgcatctgtt tttccaccat gaacagatgc acttgaaacc gcatcttcat
      181 ttccaacaag ttgttgaccc gtttgttgta aataccactc aatgattggt ttgaaatcaa
      241 gaatgtattc attgattcca gcatactctc cattttcatc atgcattgct tggtaattat
      301 gcacaatata tttttctggc acttgttttg gtacatgaac acgtaccgca tctgttgctc
      361 cgcttcgcag ttgttgaatt acccactcta catttttata cgatttttct gggtgacagt
      421 tggctaatgg attccctacc tgaccgggca cacgagcagc taacatctct ttcgcttctt
      481 ggcgcaaatt ataatataaa aattggttat tattatctgc aaaagttaat tccatcggca
      541 tcgaatctaa aaagtaattg atttgatcca ctgtcaataa cccacgattt aatttgacgt
      601 aagtatttcc agaaacggca ccgactgctt cagaagcttt ttccaaccaa tgatcatctg
      661 acatatcaac atcgggtatt gtcgtagcaa ttgttcctgt cgcatgcaaa tcttctggtg
      721 gaagcttttt aggccctgct aaggtagaca cgactttaat gaattttaca aaacttgcta
      781 atgtactgcc taaaaagtca acagttcgtg gatcaatcaa gcgatcttct tggtcaaatg
      841 cttcttttgc ttttcccaat aaaaattcat ttccgggcat cactaatgca ttcacgcctg
      901 gtgcgtccaa aatttggcgc aagtgtaatt gcgcgcgtga agttccttga tcgtagtaag
      961 aagcacccac aaccattaca ggtttatttt caagtggatg gattttaaat gatagccatt
     1021 caagtgcact tttcaatcct gctggaaccg tatgattgtg ttctggcgta gcaataatta
     1081 ccccatcagc cattaagatt ttgcgattta gctgttgaat agcaggacta tttgtttgat
     1141 catcatcttg attgaacaga ggtaaatctt tgatttcaat gatttctaaa ttaaatagtt
     1201 catgatattg tttttggata aatgttaata atttacggtt atatgaaagt tcagctgctg
     1261 atccgacgat acctattaat ttcatctttg tttgctcccc tcgattaaat cgtttcccat
     1321 gaaaagcttt cggcttcacg tttatttgct tggtgcgcat gttgcaattg actagtgatt
     1381 gtgacaaaga gtaagaaatc tttgaatagt tcacgtaatt ttgcgacttg ttcttcatca
     1441 atgagtcgtc cttgctcatc aaaggcttgg agtgaatgac ccaataaaaa ttctgagctt
     1501 ggcataattc gtgcctttaa ctctggtgaa tccaatattt ggcgcaaatg tgcttgtgcg
     1561 cgtgaagaac ctaacgtgcc ataagacgct ccggtaatca tcactggttt atccacaaac
     1621 ggaaaaatac catatgaaag ccaatttaat gcgttaatca atgaagcagg aaccgcatgg
     1681 tcatactctg gtgtgctgat gattacgcca tctgcttgtt caatttttcc agcaatttct
     1741 ttaacaacat ttggtagttc tgtgttttca ggtttgttaa atagtggcag ctccttgatt
     1801 tcgacaattt cgatttctgc ctcatttaca aaataatttt tcataaactg taataattca
     1861 cggtttgttg accgcgttga atttgttcct actaatccaa taaatttcat cttcattctc
     1921 tttcctttct aacatcgatt tctgactgtt cgcacgtact aaattttttc aaatcctttt
     1981 gtatacaaga attgattctc ttttgttaca actgctccct cgatacccgg ctgttcttca
     2041 agcgctttca acacttctaa agaagatgct ccaaataaac gtgtagtcca gatttctcca
     2101 tctacagaag aatcagacaa aatcgtcagg cttgctacgt catttttaac tggaaagcca
     2161 gttttcggat caatgatgtg atgatacact gacgaaccat tttgtagata acgttcgtag
     2221 attccagagg taactaaaga ttggttgttt agtttaacca ccgcaagcga ctcttcacgt
     2281 gaacctttag gatttcgcaa accaatacgc caagcaccat ccgaacgtct tggtgattca
     2341 ccaaaaacaa cgatatttcc tcctaagtta actaaagcaa acgctgcatt tcgctctcgg
     2401 caatgtgtaa ttaatttatc tgcaatgtaa ccttttgcta acgcccccaa gtcaatcatc
     2461 attcctggtt tggttaaaaa aacggttttc attttttcat ctaattgaat ttggtgtgga
     2521 tccgttagca gaagtaactc agttatctct gcttttgttg gaaccaatgc atcttcaaat
     2581 ccaatgtgcc atttttgtac aaccggacca atagcaatat tcagataact atttcttgca
     2641 caactatgtg cttttcctaa tttgatgagc tcaaaaagtt caggatgtac aatcacagct
     2701 tgtcgtccag cagcttgatt gatggccatt aattcagaag ttgcatcatg tgcgctgaag
     2761 cgatgttcat aaacgtgcaa ccattcgcct aactctgcta gtaatcgact aggctcttca
     2821 tgcccaactt gtaatgtaat tgttgtcccc atcatttgcc agattttcgt ttcttcgatc
     2881 acctgattca ttttgtacct tctttacttg aactacggat tacatgagta attagttttt
     2941 atttttgtta ctgttttcac aaccagatga tacgcctgct agatttattt gtcaaccgat
     3001 tttatatatt tttttatata ataaggtaat tttaatataa aattttatat tgtaaaaaaa
     3061 caaataaggg aaacaaacaa cacatttttg tgtgttgctt atttccctct aactatcgtt
     3121 ttctatttga tggttaacct acttaaaata aatactgcaa cgacaaacgg agatcaagca
     3181 tgctttgtaa cgtattttac gataattacg actttatttt attactctat cttgctgcca
     3241 tacccgtcta tccctaatca tctttggtga attttttcaa agttagcata acaaaaataa
     3301 gtattttttc cttagttaat caatagtatc atttttttca tatgatttaa ttcatcaatt
     3361 aattttttgt ttttattaat tttagcaaaa gctagtgcat cttgaatcaa ttcgagcact
     3421 tctgccttcg acttattttt agcctgtgcg ttcttcgcta attgggcagc agctcgtgct
     3481 aagtaataag tcaaatggtt atccgaacaa atatcgattg cgtaatttag tagtgcatca
     3541 cttgtttcca aatcaccgtc ttgcgcaaaa aaaacaccac aatgaaagac gatatttaac
     3601 acccgccaga tatcttctgt tgtacgaatc ggatacgtat aaattttttc aaacactcga
     3661 ttgaaataaa cttctgcttt ttccaactct ttttctctag catagaccat tccaatacct
     3721 gtatatgcca ataaacgaaa caacgtgttg gctgtttctg ccatcaacaa ctgatcaaaa
     3781 tggaacaaca catccgtaat tggtgcattc gtaaaaatca tttcaaatcc ttttagatag
     3841 tagtaacgtg caatcagctc agactcgtca attaccttgg gatcaatggc tgctaaaatc
     3901 tgtgtcaatt gttcatattc actcgtaatc agtgaaaact ctgctttttc tagctgttca
     3961 tcaagttgtg tattgatcac gttcatcgaa gaaaaaagtt caactaacgg aagattgatt
     4021 cgattacata atttgattaa aatttttaac gaagggactt gaccattgtt ctcaaattta
     4081 cttaatgttg cttgtgtaca aattccttca gacacttctt tttgagataa gttggcagcc
     4141 tttcttgccg taataaattt ttcaatgttc attattttct ctccaatcag acctcacacg
     4201 aaaatcattt ctgtctcgat tttagcatgt tttctttggg aatgctttag gttctgttgc
     4261 aaagttttaa ataaagaata aagtccctta cggtatctat gatttaagct
//
LOCUS       DACDLM010000134         4193 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.136, whole genome shotgun sequence.
ACCESSION   DACDLM010000134 DACDLM010000000
VERSION     DACDLM010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.136"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..610)
                     /locus_tag="IV356_002827"
     CDS             complement(<1..610)
                     /locus_tag="IV356_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP9016440.1"
                     /translation="MQAPIKKICVHFETKQWRNKMVATVTLYLTFTLILDLGIYLFFS
                     KQLLVKNSFGCIALMVVTLLLPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFF
                     AITGLSFFLVFDLMDYLGKRHLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPT
                     EHYFGGICILLSWGVIYLVLGSVHFRSSNYLLLSLLSIVISFF"
     gene            611..1186
                     /locus_tag="IV356_002828"
                     /pseudo
     CDS             611..1186
                     /locus_tag="IV356_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
     gene            complement(1367..2560)
                     /locus_tag="IV356_002829"
     CDS             complement(1367..2560)
                     /locus_tag="IV356_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002610375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP9016441.1"
                     /translation="MSEKRRDSKNRVLRSGESQRKDGRYAYKYVDTFGKPQFVYSWKL
                     VPTDKTPAGKREDISLREKEKEIQKDLDDGIDTIGKKMTVCQLYAKQIRHRGNVKHNT
                     KLGRERLMRILEQDRLGSCPIDSVKLSDAKEWALRMKEKGLSYKTINNDKRSLKAAFY
                     TAIQDDCIRKNPFDFQLSDVLDDDTEPKVPLTPAQEESFLSFIQGDKVYQKHYDAIVI
                     LLGTGLRISELCGLTDKDLDFENRVIIVSHQLLRNTGVGYYIDEPKTQSGVRKIPMNE
                     EVYQAFQRVIKNRKGAKPFIIDGYANFLFLKQNGYPMTAVDYGGMFGRLVKKYNKSHE
                     EALPKTTTPHAMRHTFCTRLANAGMNPKALQYIMGHSNITMTLNYYAHATFDSARAEM
                     ERLAA"
     gene            complement(2644..2847)
                     /locus_tag="IV356_002830"
     CDS             complement(2644..2847)
                     /locus_tag="IV356_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HAP9016442.1"
                     /translation="MMNHDVPIWEKYTLTIEEASKYFRIGENKLRKLAEENPASGWVI
                     MNGNRIQIKRKQFEKIIDTLDTI"
     gene            3104..3346
                     /locus_tag="IV356_002831"
     CDS             3104..3346
                     /locus_tag="IV356_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016443.1"
                     /translation="MAHQPSGSAQTECVRMPYDAPPLSCGHIYQGAIRPPGKHRNGER
                     VSRFMLPGPVRQFVTIAWMSLISRRRFMASSRHTCG"
     gene            complement(3268..3501)
                     /locus_tag="IV356_002832"
     CDS             complement(3268..3501)
                     /locus_tag="IV356_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP9016444.1"
                     /translation="MKNPNYKGIELLPLSVIEAARAGDAGAVERVLQYYSGYMNKLCT
                     RTLYDENGYPHVCLDEAMKRRLEIKLIHAIVTN"
     gene            complement(3508..3939)
                     /locus_tag="IV356_002833"
     CDS             complement(3508..3939)
                     /locus_tag="IV356_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAP9016445.1"
                     /translation="MDAIPRDYEARCMFDAFCKTVLRNEAKSYLAEMKRRRDREVSLS
                     SLSQADLDKLCTVDHYPSDSFTFSSHGYDLHINNELVAEAFAALPSMEQSILILHCVL
                     DMADGEIGGLVGMSRSAVQRHRTNTLSELRKQLKALMPKGG"
BASE COUNT         1124 a          993 c          898 g         1178 t
ORIGIN      
        1 aaaaaaaact gatgactatc gacaaaagag atagaagcag ataattagat gagcggaagt
       61 gaacacttcc caataccaag taaatcacgc cccagcttaa taaaatacaa atacctccaa
      121 aatagtgttc agttggataa gtaaaaagca agttgagaaa tctcgtctgt ttgtctatac
      181 tttttactaa tagatagaaa ataaatgcga taagtagtgc aaaaaaactt gctgttccaa
      241 gatgtctctt tcctaaataa tccatcagat caaaaaccag aaaaaagctg agtccagtga
      301 tagcaaaaaa aagattactg atcaaacagc tgataaacag gtttttcgta gtaaaataaa
      361 aaagaaacat caataataag ccaactaggt aaggaaagct cactttaggg ataggaagta
      421 aaagtgtcac caccatcaaa gctatacaac caaagctgtt ttttactagc agttgtttcg
      481 aaaagaataa atagatacct aaatctaaaa tcaaagtaaa ggtcaaataa agtgtcactg
      541 ttgcgaccat cttattcctc cattgttttg tttcaaaatg tacacatatt tttttaatag
      601 gagcctgcat atgaaaaagt attttatcat agaagataac cagtttcaca gcgaatggat
      661 catcagagaa ttggtcaatc atcatatcga gaatatcgtg cagctcactt ctatctctca
      721 aatcaatcag ttgatccagt tgggcactat tgataatcac gatgttttct ttatcgatat
      781 cgacttgaag caatcactca caggtattga tgtcgccgaa caaatacgta aaaaaaatgc
      841 acatagtaat attgtttttt tcaccgctta tacgaatttt gcagtagaga tcatcaatcg
      901 gaaaatcctt ccgattggat atatcagaaa agacaggaat ttatctgaac aaattcgtca
      961 agtgctagaa cagatcaatt ggaaagaaca gcagatcgta aatgtcgata aaatctttat
     1021 tgatcaaaaa ggtggaagtc tcgtcctgta tcctcgggaa attttatata ttgaaagtat
     1081 caaaggtttg aaaaaccaag ttatggtcaa aacaactaca gaagataaat tagtgaatac
     1141 ttctttaaaa caattgaaga cagagttaga aaagtatgct tactttttct taaaaattat
     1201 atgggatttt agattatctt tttagaagtt cttgaatgtc ggtatagccc gtgtttccgg
     1261 gcttttccgg catttttgat attgttagat acttacaaat gttcttatta cctctcacca
     1321 tttccccctc aaaagtagta aatggagtag taaaaccggc cttgtgtcag gctgccagcc
     1381 gttccatttc tgcccttgcg gaatcgaatg tggcgtgtgc ataatagttc agcgtcatgg
     1441 tgatattgga atgtcccata atgtactgca aggctttggg gttcattccc gcattggcta
     1501 accgggtgca gaatgtatga cgcatagcat ggggcgtcgt cgttttcggc aacgcttctt
     1561 catggctctt gttgtacttc ttcacaagcc tgccaaacat cccgccataa tctaccgccg
     1621 tcatgggata gccgttctgt ttgagaaaca ggaaattggc atacccgtca ataatgaacg
     1681 gctttgcacc tttgcggttt tttatcactc gctggaacgc ctgatacact tcctcattca
     1741 tggggatttt tctgacgccg ctttgggtct tgggttcgtc aatatagtaa ccgacgccgg
     1801 tatttctcaa aagctggtgg ctcacgatga ttacccggtt ttcaaaatcc aaatctttgt
     1861 ccgtcagtcc gcacagttcc gaaatgcgaa gccctgtccc cagcagaata acgattgcgt
     1921 cataatgctt ttggtaaacc ttatcacctt gaataaagga cagaaaactt tcttcctgtg
     1981 ctggtgtaag aggcaccttt ggttccgtat cgtcgtccag aacgtcacta agctggaagt
     2041 caaacgggtt ttttcggatg caatcgtcct gtatggcggt gtaaaaagcc gctttcaggg
     2101 aacgcttgtc gttattgatg gtcttataag aaaggccctt ttctttcatc cgaagcgccc
     2161 attcctttgc gtcggacagc ttcacactgt caatcgggca gctccccagc cgatcttgtt
     2221 ccagaatacg catcagccgt tcccggccca gtttggtgtt gtgcttcaca ttgccccggt
     2281 gcctgatctg cttggcgtag agctggcaga cggtcatttt cttgccgatg gtgtctatcc
     2341 cgtcgtcaag gtctttctgg atttctttct ccttttcccg gagtgaaata tcctcccgtt
     2401 tacctgccgg ggtcttatcc gtaggcacta acttccatga gtaaacaaac tgcggttttc
     2461 caaaggtatc aacatatttg taagcatatc gtccgtcttt tctctggctc tctccagacc
     2521 gcaaaacgcg atttttgctg tctcgtcttt tttctgacat ctcgtcatgc tcctttccat
     2581 gacggaaaga gccgcatata tgcttataaa ttattataac atatctgcgg ccctttttca
     2641 ctattagatt gtgtccaaag tgtcaattat tttctcaaac tgcttgcgtt tgatctggat
     2701 gcggttgcca ttcataatga cccagccaga ggccggattt tcctcggcca gcttacgcaa
     2761 tttgttttct ccgatacgga aatatttaga cgcttcctca atcgtcagcg tgtatttttc
     2821 ccaaataggc acatcatggt tcataatgca gccccctttc acaaattcaa aggtttgtgt
     2881 gatttagggg catagacgga cggctgctgg cacagctcca cgggactttc acccccgcgt
     2941 ggttctcacg cggccctacc cattgcctgc gacgctttta acgctcggac tgtggctata
     3001 agggagtatc atagtcctgc ctgtacgtcg tcgcccgcaa gccgccacgc tcacattgcg
     3061 gcgtggtgtt cctcgctccg cttttcccgt agggaaaagt atcatggcgc accagccgtc
     3121 cggctcggca cagacagaat gtgtccgtat gccctatgat gcgccgccgt tatcttgcgg
     3181 gcatatttat caaggtgcga tcaggccacc gggaaaacac cgaaacgggg aaagggtaag
     3241 ccgtttcatg ctgccggggc cggttcgtca gttcgtgacg atagcgtgga tgagcttgat
     3301 ttccagacgg cgcttcatgg cctcgtccag acacacatgc ggatagccgt tttcgtcata
     3361 gagcgtccgg gtacacagct tgttcatgta accgctgtaa tactgcaaaa cgcgctctac
     3421 ggctccggca tccccagcgc gggcggcctc gatcaccgaa aggggcaaaa gctcaatgcc
     3481 cttgtagttc gggttcttca tccgcgtcta acctcccttc ggcatcaacg cctttagctg
     3541 tttccgcagc tccgataagg tatttgtcct gtgccgctga acggcactcc gggacattcc
     3601 cacaaggccg ccgatctcac catctgccat atccagaaca cagtgcagga ttaaaatact
     3661 ctgctccatg ctgggcagcg cggcaaaggc ttcggcaaca agctcattgt tgatatgtag
     3721 gtcatagcca tgcgacgaaa acgtaaagct gtcgctgggg tagtgatcta ctgtacagag
     3781 cttgtccaaa tctgcctgtg acaaagagct tagtgacact tcacggtcac ggcggcgctt
     3841 catttcagcc aagtagcttt tggcctcgtt acgcagtacc gtcttgcaaa aagcatcgaa
     3901 catgcaccgc gcttcatagt cgcgggggat agcatccatc ttctcacccc ctttctgtgg
     3961 gggacttagg tggttctctc cctttccgct aacaagactt tgacaaggcc gccagctacc
     4021 cgctaaatac ctcctttttg aaaatttctc aaaaaatttt tttggggaca gccgggccgc
     4081 aaaagacgac aaaaatcgcc cggcaggtcg caaacctacc gggcgagaaa atgctttgct
     4141 atgctgctga tttacatggt atagtacata ctcataaccg gaatagccct gtg
//
LOCUS       DACDLM010000135         4157 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.138, whole genome shotgun sequence.
ACCESSION   DACDLM010000135 DACDLM010000000
VERSION     DACDLM010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4157
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.138"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            179..775
                     /locus_tag="IV356_002834"
     CDS             179..775
                     /locus_tag="IV356_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAP9016446.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            899..2698
                     /locus_tag="IV356_002835"
     CDS             899..2698
                     /locus_tag="IV356_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAP9016447.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(2976..3188)
                     /locus_tag="IV356_002836"
     CDS             complement(2976..3188)
                     /locus_tag="IV356_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016448.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            complement(4052..>4157)
                     /locus_tag="IV356_002837"
     CDS             complement(4052..>4157)
                     /locus_tag="IV356_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP9016449.1"
                     /translation="ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
BASE COUNT         1228 a          706 c          729 g         1494 t
ORIGIN      
        1 tttaaaaaaa acaagttatt aaataagtct ttagttggat gtttttttga gatcaatctt
       61 ttatacttat gatgaactta caaaattgtt tgttttctgt catatcaaaa aatggcgcag
      121 ttagttgctt ttctagtaaa gtatagttaa caaagaacct ctaaggagtt gatgaataat
      181 gaatattgct gcctctcgaa aactgataaa tttcatatcc attatcggat taggcctatc
      241 aatcgcgctg acgatttatt ttattaattt aggtgttttc aaagatttga atgcgttaag
      301 aggattagta ggtgattcca tcattttagg accgattatt tttgtcttca tccaaatcct
      361 gcaagtagtt attccaatca ttcctggagg gatcagtact gcagctggtg tcctgatatt
      421 tggcccttat gctggattta tctataacta tattggaatc tgcattggtt cgattatcat
      481 ttttctgcta gggcgtcgtt atggaaagcc attcatactt tccatgatta gcgataagac
      541 atataacaaa tatattggct ggctggataa tcaaaaccgt tttgagaagc tgtttgctct
      601 agctattttt cttccagttg ctcctgacga tgcgttatgt ttgatggctg gattgacaaa
      661 catgtcagtg aaacgatata cactaatcat tttgattgct aaaccactgt cgattttctt
      721 atatagtatg gccttgattt atggaggtca atatctaagt ggtcttcttg gataatattt
      781 attttgtaaa attagtcatt gattgacaat gttaaatctg ggaaagggtc tgcaaaacac
      841 actgcaccct ttcctttttc attagatttg cgctataatg tgaagagcag gtgataggat
      901 gaattatttg aaacgtagct taggtaatgc ttgggacttt ttaaaaggaa cacaagctta
      961 tttccgtgat gtcttgctga tgcatggctt tattttattt atttgtttac ccttattgag
     1021 cagtacgacc cgttttattt tacaccgagg ggcaattgac tatttgtctt atgacaatat
     1081 tccttcaatt ttttctcaac atcctggggt tctactctcg ttaatcgtag ttttgatgac
     1141 gattttactg ttagtttatt tcgaatttac ttttcttttg atgagtgttt tttttattaa
     1201 aaagaaagaa ccaatctctt tgaagcaact cttacacttg acgatacttc agctgaagaa
     1261 agtgagaccc attacttttt tgtttttcct tgcttatttt ttattgattc taccgatcag
     1321 cggattaagt tttaattctg atctactgtc aaaaataaaa atccccgctt tcattatgga
     1381 ttttattttt gctaatcgtt ggatcatcgt cagttccttt ttactcgttt atattttcct
     1441 tggctatatt gggattcgac tgatttttgc tttaccggaa atgattctac gggatcgtcc
     1501 ttttcgagca gccattcggg aaagctggtc attgaccaaa tcgcgtcttt tggccatcac
     1561 gggccaattt attgtgattg gcggtacgat tttactcctt tcttctttag gatatatcgt
     1621 tgttattttg gcacaaagta tggttgaaca atttttccca gactatgcat tgatcagcgc
     1681 tgtgtttgct atgacgcttt tacaagggat tttattattc aatatcgtga tgtctaccgt
     1741 agggattttt tatatcattg ttgatttcat ggatgacgaa ggcttcttgc ctgagatccc
     1801 taagtggttt atcccacaag cccccaactt gcgtttctct gcgctgaaaa acactggttt
     1861 gactcttttt gcagtttttt tcggtattgg cgtctgtctt tacaatatgg attatctgac
     1921 ttcagctgtt cagacaaaac cagtgactgt ctctcacaga ggtgtgagta cccaaaatgg
     1981 ggcgcaaaat actttagaag cacttgaaaa aacaagcaga gactatcatc ctgattatgt
     2041 agagatggat gttcaggaaa caaaagatgg tcatttcgta gtgatgcatg atgcaaatct
     2101 tcgtcactta acaggggtaa atggaacacc acaggatctt acattgaaag aattgacaaa
     2161 tcttacagtt actgaaaacg gagtgcaagc ccctgtttgt tcttttgatt cttatttgga
     2221 aaaagcacat aagctaaacc aaaaattact tattgagatc aagacctcta aaaaagattc
     2281 ggatgacctt gtcgaacgat ttgtccataa ataccgcaaa gttatcttag agaaccatca
     2341 tattttgcaa agtttgacgt accaaaccgt ttcagattta aaagaagcag aaccaaactt
     2401 ttatgtgggc tacatcttac ctttcaatat tgttgggccc cctgtgacgc ctgctgattt
     2461 tctgacaatg gaatatagta cgatcaaccg taacttcatt aattctgccc accaagacgg
     2521 aaaagaagta tatgtatgga caatcaacga ttcagatgct atgagtcgca tgatgtttta
     2581 tggtgtggat ggtatcataa ccgatgagat gggactacta aatgaaagtg tgaaacaaac
     2641 agatgaagaa atcacttatt cagataaact gctaaatttt gttttgggag tcggctaatc
     2701 aaaaatcgtt aatgaaaaaa gtctttatac aacaaaaaac gcataacctg ccaccgcagg
     2761 tatatgcgtt ttttgtttga cgctcataat gtgtgcttaa ctttctcttg attccttcat
     2821 cgcacgaaca atagctaaaa tagcaggaat tgcagagatc actgcaagaa taattcccat
     2881 tttccctgaa ctttttcttt ttggcatatc ttctcgctcc cttctgtctt tatttatatt
     2941 ataagggagt tcttgcgaat tctcaaaaat actgtttaag aaaccaattc agcaggtgcg
     3001 ctaatatcac agaattttac gagcatgcga tacttgcttt cattgataag ttgatagtct
     3061 cgttggtcat aactttcaac atacacgaca gccgtgttga tatatgtacg ttcaatacag
     3121 ccgattagtt catgagatac tccgatcggt ttgcatatat aagatcttcc tacttctgct
     3181 tttaccattt cattccctct tttctttatt tttattttgt tttttcttta ttttataata
     3241 acaaattacc ttgtatttga aaacgttttt atccattttt ttatttttta ttttgagtat
     3301 ctttctgctt tttagataac tattttttaa cacgatctta gacgttgtga caaaaacgtt
     3361 tgtttatatt cctatgttgt tcgtgcgttt ttttctttat attgctaagt tatttataaa
     3421 gaggtgagca tatgatttat attcaagcaa tagtatttgt aaccttgatg attgggctac
     3481 ttatcggatt aaaagaaaat agctaaacca tttaagaaaa aataaataag gaaaatgata
     3541 aatgcttttt aattgcatca aaaaacgtac gatgctaaac ttggtataag ttcgaaagtt
     3601 taaaggaaac tttcaagaac taaattacat tacaaaggag atgaatttta tgacgtttac
     3661 aaaaacaaat atgcaatacc gcgtagcttt tgatacaact tctaaccgtt ttatggcgat
     3721 tgatgcacaa aacgaaaata acgttgcgtt tggtattaca atcgaacaag cagtccgagc
     3781 attaaacgaa tctagataag gagtgaacca ttccaaatgg cgactgatga gatctcggaa
     3841 aatcaataaa agacgtttgt aacggtaatc cgcgacaaac gtctttttgt attcattaca
     3901 tatatttgga aattgtctct ctttatctct agacctaaac aaaaacacaa gttctaatat
     3961 caaccatctc gttttttatg acaattttgt tagctgtttc gatgataata ttccgttatt
     4021 atctgtataa tatttaatat aatcttaatt gtcaaattaa gttagacaga tcatcaatac
     4081 ttacgtaact caaaaatact tccaaaggtg ttcgataatc cagtgatttt ctaggaatat
     4141 tatttcgttt agatgcg
//
LOCUS       DACDLM010000136         4116 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.139, whole genome shotgun sequence.
ACCESSION   DACDLM010000136 DACDLM010000000
VERSION     DACDLM010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4116
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.139"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(88..648)
                     /locus_tag="IV356_002838"
                     /pseudo
     CDS             complement(88..648)
                     /locus_tag="IV356_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177795.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            882..2174
                     /locus_tag="IV356_002839"
     CDS             882..2174
                     /locus_tag="IV356_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP9016450.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCLISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYIRRLWRPGFKAHLTETDIVDRLLKRSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
     gene            complement(2462..3946)
                     /locus_tag="IV356_002840"
     CDS             complement(2462..3946)
                     /locus_tag="IV356_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HAP9016451.1"
                     /translation="MKKLSQKRLAQIIIDSRKSLKMTQQQLAVATGINRALISRVESL
                     DFIPSIQQLESLAEVLNFEPTDLFINESNKSNRTKHQSKNIAVAGTGYVGLSIATLLA
                     QHNQVTAVDILPEKVKQINNKKSPIQDDYIEKYLAEKNLNLIATTDGAAAYREADFVV
                     IAAPTNYDSKQNYFDTSAVESVIKLVLEVNPKAIMVIKSTVPVGYTESIRKKYNTKNI
                     LFSPEFLRESKALYDNLYPSRIIVGTDQTDKTLREASHTFADLLQEGAIKKDIETLFM
                     GFTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLNTQEIIHGVCLDPRIGTHYNNPS
                     FGYGGYCLPKDTKQLLTNYNDIPQNMMSAIVDSNRTRKDFIADRVLQKTGYYSYDDDN
                     TFDLSLEKEVIIGVYRLTMKSNSDNFRQSSIQGIMKRIKAKGATVIIYEPTLKDGSTF
                     FGSKVINDLEKFKSISHSIIANRYDSILNDVKEKVYTRDLFQRD"
BASE COUNT         1257 a          719 c          718 g         1422 t
ORIGIN      
        1 cattttgtag agagtgggac aatagtcctt tctccaaaag aaaacaagtc cgattttgat
       61 ggttaatttc aaaatcggac ttgttttttc ttcttttaaa taaggcaaga tttcttcttt
      121 ataaagggca taatagaatt cgtttgattg cttatccaaa gcagtttcat aacgattcgt
      181 ttctttacgc cagaagaaac tgaacttgtt ggcatctgct tcaatttttg taccatcaat
      241 aaatattgct tcattatcaa ttacttaatt ggtgatcgat tggcggctaa ataagacaaa
      301 cgcttcagct aaaaggtcag cgggtgtttc ctgacttcgg aatcgattga tggtccgata
      361 gctgacttgt tcgtggttag ccaaccaaca catacgatag ctgtcatcta atagaaattc
      421 aattttccga ccagaaaaga cacgctgcat ataagcatat agaataattt ttaacatcat
      481 tttggggtgg taggccggtc gtcctagtta ttcttataat tcaagaaaga gtgtttgtgg
      541 cattgctacg actaaagcgt tgactgcaaa agcgacatct gtttcaggaa tatattgttc
      601 catatctaat ggtaaagttg tttgattgat gggataattt ttaaacataa agtactcgct
      661 tcctttctga ttgggcttgg tcactttaat cttacaggga tgagtgcttt ttgtgtacct
      721 taaaatcaaa aaaagtgggg caataatcag attttggctc tatacttttt gatgttggtg
      781 gatgacacca gcatcttttt tattttccaa aacatataga aaagacacct tgaaatcctt
      841 tagaattaat ttggcgaacc aacccaaaag gaggaatcaa gatgtcttac actcacctta
      901 tcaaagaaac attagatatt ctagacttat cagttacttt taacgaaaat tgtctcacaa
      961 aagaaaaata caaagggcaa atctgtcata tttatcgtgg aaacttgatt tatacagccc
     1021 aagaatgcat ccactgtaaa caccagattg cttcagatat tgtgcgttgg ggtacaacaa
     1081 ccgtccggtt gttaatgaac gatgtttctg aataccgtac ctacctcgaa ttgaaaaagc
     1141 aacgcttcaa atgcaaagct tgtcagcgga cctttgtcgc agatacttct gttgcgaaaa
     1201 aacattgtct catcagtgag aaagtccgct ggtctgtcgt gactcgtctg aaaaaaaata
     1261 cctcaatgac agagatcgcc gctcagaaaa atctatcggt ctcttctgtt taccgtatta
     1321 tgaagcgatt ttatcgtccg ttgaatcctt ttcggacacc gttacctaag gtactttgtt
     1381 ttgatgaatt caaatcagtt cggggtgttt caggtgctat gagtttcatc atgatggatg
     1441 gacaaacaca gcgcttattg gacattgtcg agaaccgaca actgcctttt ttaaaacgtt
     1501 attttagtca tttttcacga gaaattcgtg aagcggtcga atggatcgtg attgatatgt
     1561 acgctcctta tgtatcgctc gttaaaaagc tgtttccaaa agcacagctg attattgacc
     1621 ggtttcacat cgtccaacat attggtcgta cctttcgcaa tcatcgaatc aaagaaacga
     1681 accaactatt aaaaagcaaa gaacaaaaac actatcaatt aggtaagcaa ttaaaaagat
     1741 actggaaact tcttcaaaaa gatgaacgca agcttgatta tattcgacgc ctttggcgac
     1801 ctggcttcaa agctcattta acagagaccg atattgtgga tcgcttactg aaaaggagcc
     1861 ctgctttgcg tgtaggctat cagttatatc aagactttct ttacgctgta aaggaacgag
     1921 actacgtatc gtttgaagaa ctacttacca ataatatcat gcttcccgaa ggctatcaga
     1981 cgaccttgag aacgttccag aaatttctgc cacaaatcaa aaatgcttta caacaaagtt
     2041 attcaaatgg cccacttgaa tgtctgaaca accatatcaa agtgttaaaa cgaaatgcat
     2101 atggctttcg tagcttttat aatttcaaat tgcgcatcat gattcgtcat ggcaacgcat
     2161 tgattttcaa ctaaaaaaga tcaagaggaa ctgatccact tgatctccaa ttattctaag
     2221 atttctcttt accaacatca tttgacaaag agcccagatt tttttctgac tattgtccca
     2281 ctccccttgc gttgtaaaaa ttttgataat tagatttctt aaagttggta atcttttatt
     2341 aaaaatcttt tctaaagaga gacgtaattc ctcctagcgc ttaattaatg ggtctaaatg
     2401 aaaggataaa aattagtctt gctgtttatt gtaaattatt ttaatgtatc taatcattcg
     2461 tttaatcccg ttgaaataaa tctctagtgt atactttttc ttttacatca ttaagaatac
     2521 tatcatatcg attagcaata atactatgac ttatgctttt aaatttttct aaatcattta
     2581 ttacttttga accaaaaaat gtactaccat ctttaagtgt tggctcgtaa attatcacag
     2641 tggctccctt tgccttgatt cttttcataa taccttgaat agaagattga cggaagttat
     2701 ccgaattact tttcattgta agcctataga ctccaataat cacttctttt tctagagaca
     2761 aatcgaaagt attgtcatca tcgtaagaat aatatccagt tttttgaagc acgcggtctg
     2821 ctataaagtc ttttcttgtt cggttactat cgacaattgc actcatcata ttttgaggta
     2881 tatcgttata gttagttaga agttgttttg tatctttcgg taaacaatag cctccatatc
     2941 caaaagatgg attattataa tgtgtgccaa ttcttggatc taagcaaacc ccgtgaatga
     3001 tttcttgtgt atttagtcct ttcatttctg cataagtatc cagctcattg aagtaagata
     3061 ctcgaagtgc aaggtaagta ttagcgaata atttaactgc ttcagcttct gtgaatccca
     3121 tgaaaagagt ttcgatatct tttttgattg ctccttcttg gagtaaatct gcaaaagtgt
     3181 gagaggcttc tcgtaaagtt ttgtcagttt ggtccgtgcc gacaataatt cgcgaaggat
     3241 atagattgtc atataatgcc ttagattctc tgagaaattc tgggctgaat agaatatttt
     3301 tagtattgta ttttttacga atactttcgg tatagcctac gggtaccgtc gacttgatga
     3361 ccattattgc ctttggattg acttctaaca ccaatttgat tactgactct acagcagaag
     3421 tatcaaaata attttgttta ctatcataat ttgttggagc agcaatgaca acaaaatcgg
     3481 cttctctata ggcggctgca ccatcagtcg ttgcaattaa attaagattt ttttcagcta
     3541 gatatttttc aatgtaatcg tcttgtattg gagatttctt attgttaatt tgttttactt
     3601 tttcaggaag aatgtctact gctgttacct gattgtgctg ggcaagaaga gtagcaatgg
     3661 aaagacctac gtaaccagta ccggctacag caatattctt cgactgatgt tttgttctgt
     3721 ttgatttatt tgattcattt ataaatagat ctgttggttc aaaatttaga acttctgcta
     3781 atgattctaa ttgttgtatt gacgggataa aatcgagaga ttctactcga ctaattaagg
     3841 cacggttgat accagtagct actgcaagtt gttgttgtgt cattttcaga gattttctag
     3901 aatcaataat gatttgagct aaacgttttt gagataactt tttcatgatg cactcctttt
     3961 tttgttgcta ataataacaa acaatttttt cttctataac agaatagctt attattaata
     4021 aaactgtcaa tttttttatt gattaaaaag atattttttg attttaagta ttttcaatta
     4081 ttttttgtta cttaaaataa ctttatagat tgtgaa
//
LOCUS       DACDLM010000137         4063 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.140, whole genome shotgun sequence.
ACCESSION   DACDLM010000137 DACDLM010000000
VERSION     DACDLM010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4063
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.140"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            269..679
                     /gene="tagD"
                     /locus_tag="IV356_002841"
     CDS             269..679
                     /gene="tagD"
                     /locus_tag="IV356_002841"
                     /EC_number="2.7.7.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate cytidylyltransferase"
                     /protein_id="HAP9016452.1"
                     /translation="MKRVITYGTFDLLHYGHINLLKRAKQYGDYLIVALSTDEFNWNA
                     KQKKCYFSYEKRKQLLEAIRYVDLVIPEENWEQKVKDIKEYHADYFVMGDDWAGHFDE
                     LEQLTDAQVIYLPRTPEISTTQIKNELNSLNSDK"
     gene            855..1268
                     /locus_tag="IV356_002842"
     CDS             855..1268
                     /locus_tag="IV356_002842"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HAP9016453.1"
                     /translation="MISISHSIKELFTIKDKNIEINSFQETFYKDKKAIVIEGPLVRT
                     FRHCLFCKESAKQIEKNGKKISMIILNRSGNKQTYLRLRKQHYHCQSCGKYFTAHTYL
                     VAPSCFISKQVHYTILEELTERQALKTIAKRCDFQ"
     gene            1425..1682
                     /locus_tag="IV356_002843"
     CDS             1425..1682
                     /locus_tag="IV356_002843"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP9016454.1"
                     /translation="MTFCPAGEKKDLIAYFMRFTRKAHMGVRYIVTDMNAPYFSLVKE
                     PFPNAQIIIDCFHIGQHLNKFFDRVRKRVMKQLNQKCQRHL"
     gene            1769..3007
                     /locus_tag="IV356_002844"
     CDS             1769..3007
                     /locus_tag="IV356_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HAP9016455.1"
                     /translation="MRKDIREGVMIYVINEIKPNYAALAKQYDCDYRTVKHAYEEAQV
                     KESKPPERKKRPSKLDPYREIIQDKIKDQCSAYSIFKFIEHKGFGGSYSLVKTYCRQI
                     KQAKVHKATVRVEHSPGLSAQVDWKEDMRLISNQGEIFEFNIFLYVLPYSKKKYVTLT
                     FDRKQDTLFECLDDAFYQTGGVPKEIWFDNMKTVVDHSRSQFSKPHFNKRFYAFSKDA
                     GFTPIACRPFRPQTKGCVEALARTVDRLRVYNHEFYDAVELCHLVNNLCVELNNEVSQ
                     STDQTPDERWQTNEKEHLHPYQKNLLNPYFEDFIRRKVTKEEMVIFRKCRYSVAPRYI
                     GKEVEIELSDKEDQVQIYYNGELIRSHPLTTKQLNYHEEDYFQILKSDVMSHKEDDGI
                     RAYTRESLKQYDLVEVADEE"
     gene            2997..3737
                     /locus_tag="IV356_002845"
     CDS             2997..3737
                     /locus_tag="IV356_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP9016456.1"
                     /translation="MKNSHYQELMTNLETLGLNHMREYVPNYIEVANREELSLTEALL
                     ELTRREVDHQNKQKMNRVVARARFSKRTSLEEFDFAFQPSINKREVLDLRHMGFVEKH
                     ENLVFIGSPGVGKTHLTIALGIEACRQGYRTLFITCHELLLRLRTAYEKGTLERVLKR
                     YARYDVLIIDEIGYLPIQKQEADLFFQLLAMRYEHRSTIITTNIVLSRWGELFQSSEI
                     AAAILDRLVHHVKVFKITGKSYRMRDKI"
BASE COUNT         1362 a          786 c          761 g         1154 t
ORIGIN      
        1 gctattccag caggccaaaa aagtaaagta tcatatctag taggtaatag taaatacggg
       61 cctattgctc gtaacattaa aataaaacca aaataaataa aataccaacc tttcacatat
      121 tttaaaaatc tttcattcaa catttttcct ccatccacct atttctcata aatatttctt
      181 atccttttta ggataaactg gtcctttcaa ttctaacaaa aaaatgctaa actaacaatg
      241 tatattaatg aatttcgaga ggtgaaagat gaaaagagta attacttacg gtacctttga
      301 tttgcttcat tacgggcata tcaatttact gaaacgagca aaacaatacg gagactatct
      361 tattgttgcc ctttctacag atgaattcaa ttggaatgcg aaacaaaaaa aatgttattt
      421 tagttatgaa aaaagaaaac agttacttga agctattcgc tacgttgatt tagttattcc
      481 tgaagaaaat tgggaacaaa aagtaaaaga tataaaagaa taccatgcag attatttcgt
      541 gatgggcgat gattgggctg gacattttga tgaacttgaa caactaacag atgcacaagt
      601 gatttattta ccaagaacac ctgagatctc tacaactcaa ataaagaacg aacttaattc
      661 tttaaatagt gataaataat attttttaaa caataaaaga acaatatatc tggataagac
      721 gtaaaaaaat ggctctataa tttctaggac tgatagaatt ttctgtcggt cctagatttt
      781 ttgtaaaaaa aaacagacat aaaaaaattc cgatagaata gagtcgtcta aaacatcaat
      841 ctgaaaggaa gtttttgata tccatttctc attctatcaa agagctcttc actattaaag
      901 ataaaaatat tgaaattaat tcttttcaag aaacttttta taaggacaag aaagccatcg
      961 taatcgaagg tccattagtt cgcactttta gacattgtct attttgtaaa gaatctgcaa
     1021 agcagatcga gaaaaacggc aagaagattt caatgattat cttaaatcgc agtgggaata
     1081 aacaaaccta tttgcgtctt agaaaacaac attaccactg ccaatcatgc gggaaatatt
     1141 ttactgctca tacgtatctt gtcgctcctt catgttttat ttcgaaacaa gttcattaca
     1201 cgatattaga agagttgacc gagcgtcaag cattaaagac aattgcgaaa cgttgtgatt
     1261 ttcagtaacg acagttcaac ggacattatc tgctctatcg gcaacgctgc gacagaagct
     1321 agactattta cctcattgtt tactattcga cgagtttcgc tctctttcaa ttttccatgg
     1381 gaagttctcc ttttcttgta tgaattgaga gacagggaag ctctttgaca ttttgtccag
     1441 ccggagaaaa aaaagatttg attgcttatt tcatgcgttt tacaagaaaa gctcatatgg
     1501 gggttcgata cattgtcaca gatatgaatg ccccttattt ttcattagtc aaagaaccct
     1561 tcccaaatgc acaaatcatc attgattgct ttcacattgg gcaacacttg aacaagtttt
     1621 tcgatcgtgt tcgaaaacgt gtgatgaagc agttgaatca aaaatgtcaa cggcaccttt
     1681 aaaatgtagg aaaacggcaa tttaaaattg ttggtttacc tacatttttg tatgctcttc
     1741 ttatcccaaa tgaaatggag gctcagggat gagaaaagac atacgcgaag gagtgatgat
     1801 ctacgtgatc aatgaaatca aacccaatta tgctgcacta gcaaaacaat acgactgcga
     1861 ctaccgaaca gttaagcatg cttacgaaga agcccaagtt aaagaatcaa aacctccaga
     1921 acgtaagaag cgtccaagta agttagatcc ctacagagaa atcatccaag acaaaatcaa
     1981 agaccaatgc agtgcttaca gcattttcaa gtttattgag cacaaaggat ttggaggaag
     2041 ctacagttta gtaaagacct attgtcgcca gattaagcag gcgaaagtac acaaggcaac
     2101 cgtccgagtc gaacatagcc ctgggctttc tgctcaggtt gactggaagg aagatatgcg
     2161 actaatcagt aatcagggcg aaatttttga gttcaatatc tttttgtacg tcttgccata
     2221 ttccaagaaa aaatatgtca cactaacttt cgaccgaaaa caagacacac tctttgagtg
     2281 cttagatgat gcgttttatc aaaccggtgg cgttcccaaa gaaatctggt tcgataatat
     2341 gaagacagtc gttgaccatt ctcgtagtca gttttccaaa ccgcatttca acaaacgttt
     2401 ttatgctttc agtaaggatg ccggcttcac accaattgcc tgtcggccat ttcgtccgca
     2461 aacaaagggc tgtgtcgaag ctttagccag aactgttgac cgcctacggg tctataatca
     2521 tgaattttat gatgccgttg agctgtgtca tttagtgaat aacctttgtg ttgagttaaa
     2581 taacgaggtt tctcaatcaa ctgatcaaac accagatgaa cgttggcaga cgaacgaaaa
     2641 agagcacctg catccatacc aaaaaaacct tttgaatccc tattttgaag actttattcg
     2701 ccgtaaagtc accaaggaag aaatggtcat tttccgtaaa tgcaggtact ctgtggcgcc
     2761 tcgctatatc ggtaaagaag tcgaaatcga actctccgat aaagaagacc aagtacaaat
     2821 ctattataac ggagaactga ttcggtcgca tccattaacg acaaaacagc tgaactacca
     2881 cgaggaagac tatttccaaa tcttgaaatc cgatgtcatg agtcacaaag aagacgatgg
     2941 aatcagagcg tatactcgtg aaagtctcaa gcaatatgat ctggtggagg ttgccgatga
     3001 agaatagcca ttaccaagaa ctgatgacca acttagagac tcttggtttg aatcatatgc
     3061 gggaatatgt tcctaactac atcgaagtgg ccaatcgaga ggagctttct ttaacggaag
     3121 ctcttctcga gctgacacgc agagaagttg atcatcaaaa taagcaaaaa atgaatcgtg
     3181 tggtggcacg cgcccgcttt tccaagagaa ccagcctgga agagtttgat tttgccttcc
     3241 agccaagtat caataagcgc gaagtgctag acttaaggca catgggcttt gtggaaaaac
     3301 atgagaactt ggtttttatc ggcagtcctg gtgtaggcaa gacacatctg acgattgcat
     3361 tgggaatcga agcctgtcgt caaggctatc ggacactatt catcacctgt catgagctgc
     3421 ttttgcgtct gcgaacagcc tatgaaaaag gtaccctaga gcgtgttctc aaacgatacg
     3481 ctcgctatga cgtcttgatt attgatgaga ttggctatct tccgattcaa aaacaggaag
     3541 ctgatttatt ctttcagctt cttgccatgc gctatgaaca ccgctctacg atcattacga
     3601 cgaacattgt cttatctcgt tggggggagt tgttccaaag ttctgagatc gcagctgcca
     3661 tccttgaccg tttagtacat cacgtcaagg tgttcaagat cacaggcaag tcttatcgta
     3721 tgagagacaa gatctaaagt gtcgattgtc gacaattact attgccgaaa acctacattt
     3781 ttatcctgcc caaaacctac aattttaagc tgcccttgac atcaaaaaga cacttcacaa
     3841 gctaagtgct atcgacaatt gaaacctttg tataaattac ttctataatc agatgacgag
     3901 ttggattata caacattcaa gaaatggcag aattttcaat ggcgctattt aacagaaagt
     3961 gaagtagttg attgtctacc ctcaatctct tatgaactta aaatggctta gcagtattat
     4021 caaaagctgc ttaacaatta tcacaagaaa cagctagcta ctt
//
LOCUS       DACDLM010000138         4015 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.141, whole genome shotgun sequence.
ACCESSION   DACDLM010000138 DACDLM010000000
VERSION     DACDLM010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4015)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4015)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4015
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.141"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            58..510
                     /locus_tag="IV356_002846"
     CDS             58..510
                     /locus_tag="IV356_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016457.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            524..1213
                     /locus_tag="IV356_002847"
     CDS             524..1213
                     /locus_tag="IV356_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016458.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1338..3689
                     /locus_tag="IV356_002848"
     CDS             1338..3689
                     /locus_tag="IV356_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HAP9016459.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3769..>4015
                     /locus_tag="IV356_002849"
     CDS             3769..>4015
                     /locus_tag="IV356_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016460.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKE"
BASE COUNT         1387 a          514 c          822 g         1292 t
ORIGIN      
        1 caattatctt atcgtagata tatattataa atttaataag aaagcgaggt gagaatcgtg
       61 aaaaaaacga tactaagtat tttttcagta tttacaatat taattggggg ctattttctt
      121 ttgaatttag attctgttaa ttcaaacgct caaataaaag atcaaagagt agctgaacat
      181 aataataaaa aaatgagttt gaccaaaaat atctattcta tgtcagatga agaattgtat
      241 aaagaatttg gtgatttatc cggggaacag ttagaagaaa gtattccagg aattagtgac
      301 tcagataaaa ttgttgtctt gtctgctggt gggcaattaa tgggagatgg caaatccgaa
      361 ttagttagtt ataaacaaaa tcacagacag tttattgatg ttaatactga ttccaacgct
      421 atttcgatta aggatctaaa agagctttta aatagtaaaa gaaatgaatt aaagcagata
      481 aaagaaacta attcagtgga attagagtaa aggaagattc attatgaaaa agatttttgg
      541 tgtttctgtt gggctactta tgatgttaac atttggaaat gcagtatatg ctgctgagaa
      601 agaagttatt tcagatccag agcagtacgc ctcacgatac tttgctgatt ttgaagaaga
      661 agataaagta cttgcattgc cagaaggtgg ttttttaaaa ggggaagcta aaattgtatc
      721 tatggataat ccagatataa ttcaaggttc atataattca gaaactgatc ctgcttcagt
      781 ttcagtgaca gaagcaaaaa aaattgttgc tgaaaaattc aaaaatgata ttgaaactac
      841 tccaattatg cctcgaggag catttccacc cgatgttggt actagcggac accttcttgt
      901 actagcagga ggaggaagct ataaatcaca gccatttagt ggtgcgggat ggcgttttgg
      961 aggtatgggt gtaaaaccag ctgatggtac aggcaacttt ttacgttgga aatcctacat
     1021 tgacgatgga agagtaggaa atgtaaatca agccaacgca actaaatctg gttctattca
     1081 aggaatggca ttgtatgctc gtgaaggatt caaatacttt gcaccaaacg ggcctggttg
     1141 gacaatgaat ataggtattt attacactta taatcctgtt gcaggtacgt attatgttgt
     1201 tcaaaatatt taataaaaca gcacaaagag atttctttgt gctgttttat tatttttagt
     1261 tgttgacaaa cactaaaata taaaatataa tcaacacata aacgaacgta tgttcggcaa
     1321 gaaagcaggg gatttttatg gatgagatgg ttttaagtac tcagaaatgg ctaaacaaga
     1381 aatacagtaa tgttacaggg tttgataagg ttccagaaaa tgggcgaaca gggtggccta
     1441 caatctatgg acttattgaa ggactacaag tagaacttgg tattactaat ctagtagcta
     1501 attttggacc taccactgaa aaaatgtacg ataatcaggt tactcctaaa tggggcaaaa
     1561 atctacctaa aaatattgta tttcttattc aaggtgcctt ttggtgtaag gggattaatc
     1621 caggtggctt cgatggggta tatactccat atttagatac tgctgtaaaa gagttgcaga
     1681 ctgatgcagg gtttaatgga agcgctgtaa ctggagtttt ggatgcgaaa tgggccaaag
     1741 cgttatttga tatgagtgct tttgttcttg ttcccggcgg agatagtaaa attagaaaaa
     1801 tgcagcaatg gttaaatgta aattatttag aatacacggg aataatgcct tgtgatggta
     1861 tttatcaaag aaattcaaat caagcattaa tttttgcatt acaagctgaa ctaggatatt
     1921 ctcccagtga agcaacaggg tcttatggta atgggacaac tagtaaaact tatcctgtgt
     1981 ctgaaggtaa ctcgggaaac tatgtaagaa taattcaata tggattatat gttaatggtt
     2041 attttgaaga cggtacattc gatggtattt tcactaaata tatgggttta gaagtactgg
     2101 cattccgaaa atttatggta ttgcctgaat atactgaaat agcagatgtt gttgtaataa
     2161 aaggactatt gtctagcgct ggagatatta gaagatctgc agatggcgca gatacttcta
     2221 cgcaattaac tagatctcaa atccaaacat tggttgataa tgatataaaa atagttggta
     2281 gatatcttac tggtactgtt ggaattggaa aagatgaacg aaataagtat ctaactacag
     2341 aggaattgaa taatattttt tctaaaaatt tatctgtgtt tcctatctat caagatggag
     2401 gtgcagcatt agcttatttt acttatgatc gtggcttatc agatggtaag aaggctatag
     2461 atgcagcaaa aaatctaaat ataccattaa caacagttat ttattttgct gttgatctag
     2521 acatgttagg ggaagaaatt cttgcatatg ctggagaata ttttaagggg gtatctgctg
     2581 taatgtcata tagcgggtat caaacgggtg tttacggaac aagaaatgtt tgttctcaaa
     2641 taatcaataa cgggtatgct tcgtttgcat ttgtttcaga tatgtcgact ggttatagtg
     2701 ggaatttagg ttttcctatg cctagacaat ggtcttttga tcaatttgtt gaatttacca
     2761 taggaagtgg caacggagct gttggtatcg atttaatcgc tacatcgggt agagatagcg
     2821 gatttaatga gttatcaaat gatactaata atgataatta cattgccaaa tacaatcaga
     2881 aggttataaa tcagatggta cgtgcgtatc aatatctatc acaagctggt cttgataatc
     2941 cttggaaccc tcatttgaca ttttatagat atgtaaatta ttctggtttg tcatgggaca
     3001 tcatttcttc tcctgtaaca gagcatgata gaaaaattta tgatgaatat aggaataaat
     3061 taactaatag cgagggcctg tataattatt ttatagatcc taatactggt tcaataatag
     3121 gtttgcctca cttaattgtg acgttacaat cacagatgtt tctagccgac acaatcaatg
     3181 atagtgtttc tgactttgca ggttggttag gagatttaat gacttgctgg ggtgaagtta
     3241 agaaattagg aatacaaatg gagcaaggtg tatttgcatt agtaggtacg gctgcaggtg
     3301 gaacatttag tctagaagat ttataccaag atgttgacgc ggtaaatgtt tataccttag
     3361 caaaaagaaa ttctgattca acagctttat cggctttaaa aacgtactat tgtgataagg
     3421 gtgctattga tagatttaat caatttgtta agaacagatt tggttcttca gataaaatcg
     3481 cttcagtaac aaatagttta ttagaaaatg acgaaacagt tgatatctta ggtgtaggga
     3541 taatttcatt tttcattgat aaaatagtta ataattcact tgggacagat tttacttatc
     3601 ttgattttat tggagatgag gggaaagttg caaatggatt ttctgaaaaa attattcaat
     3661 ttcaagaaaa tagaagtaaa cttaattaag aatcgtttac tatttaaaca gtgtcctttt
     3721 cctttttaaa tatatacgat aaaataagta tatgaattgt aaaaggacat gatgattatg
     3781 gaagaaatag aatggaataa tctgactcaa aataataaaa ataattctgg atgtggaatt
     3841 atctttatgt ttgttatagt tttgggaata gtagtacttt taataactgt caagatagta
     3901 gattactttg cgaatactcc tgaagaacaa atacagagaa aacttcctga gtttgaaaga
     3961 gtaccacctt atgatccaag agataattca tttcaagtaa aaaaattaaa agagt
//
LOCUS       DACDLM010000139         3886 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.144, whole genome shotgun sequence.
ACCESSION   DACDLM010000139 DACDLM010000000
VERSION     DACDLM010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3886
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.144"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            3..1085
                     /locus_tag="IV356_002850"
     CDS             3..1085
                     /locus_tag="IV356_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017414133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP9016461.1"
                     /translation="MNDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTDT
                     RVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINAE
                     FKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKIIS
                     LEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVKN
                     DGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKEDG
                     ELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISIT
                     MDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1303..2445)
                     /locus_tag="IV356_002851"
     CDS             complement(1303..2445)
                     /locus_tag="IV356_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP9016462.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2450..2635)
                     /locus_tag="IV356_002852"
     CDS             complement(2450..2635)
                     /locus_tag="IV356_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAP9016463.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(2989..3234)
                     /locus_tag="IV356_002853"
     CDS             complement(2989..3234)
                     /locus_tag="IV356_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002412373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP9016464.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3228..3629)
                     /locus_tag="IV356_002854"
     CDS             complement(3228..3629)
                     /locus_tag="IV356_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAP9016465.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
BASE COUNT         1288 a          695 c          586 g         1317 t
ORIGIN      
        1 atatcaatga tgatggctca agaaaaaaag tggagaaagt tggcggagac acccgaccag
       61 aggccgaagc tgctttacga aaagttttat cagatattga cgaaacagga caatactttt
      121 taggtacgga tactcgagta aaacaatacc ttgatttttg gatggaggaa tacgttaaac
      181 taaatctaaa atacaatacc tatgaaaact accgatttac catcaaaaat catataaacg
      241 gttatttagg aaagaaaaaa cttacggatc tctcccctgc tcttttacaa aatttcatca
      301 atgctgaatt taaaaagggt tactcgaaga aaacaatgac tattactcac tctgtcctta
      361 agaatgcgct gaatatggcg gtttatcctt ggggattaat caagcaaaat cctatgctgt
      421 atgtaaaaat accaaaatat gaagcacgac caacgactaa aaaagatcta aaaatcattt
      481 ctcttgagga ctttgatcat atgctagaaa ttactcctga aggacatcct ttctatattc
      541 ctttgaatat tggattttat acgggaatgc gcgttggcga agtttgtggt ctgacgtggg
      601 atgatgtcga tttttcaaat ggaacaatta ctgtagagaa acaaatggta aagaatgacg
      661 gcgcatgggt atatggtacg ccaaagacaa gcagttccaa tcgaacgatt tttattggac
      721 aaaccttgct agcaattctg aaaaaacata agaaacaaca attagaaaat cgaatgaagt
      781 atggaaagct ctacattgat tcaaatgcag tatgtacgaa ggaagacggt gagctagtta
      841 cgccaagtgt agtgaaatgg aatactagga ggatatcgaa tgcactctcc ctctctttta
      901 acttccattc tctcagacat actcatgcta cacttcttct cgaaaatggc gcaaaaatga
      961 aagaaatctc tgaacgattg ggccacagca gaatttcaat tacgatggat acttactcgc
     1021 atgtaacaga taagatgaga aatgaaacgg tcgatatcat ggaaaatctt agaaagaatt
     1081 cttgattttt gccaccgaaa aaaaccaccg gtggcaaacc ggtggcaaat ccatgtaaac
     1141 atggtttatt ttttacactg ttttcaaaca aacccttgct atttcttcgg ttcgtcctcg
     1201 tccattttcg ataccgacag ctagcttata acccaaggta tatcaacata aaaaaataaa
     1261 aataggctat gacagcagcg tgacagcaaa aaagatggaa agttaaatat caaacctcgt
     1321 aatttcattt gcgagtgctt gatttgtttc tggatataag tgtccatatt tgtccaaagt
     1381 agttttaata gaggcatgac ctagacgctt agatattgca tagatatttt tattatgttc
     1441 aattaaaaag gcaacatgcg agtgtcttaa tccatgcata tgaattggtt ttactcctgc
     1501 aatttcagct agttttttta ttctgcttaa aatagttctt ggagatggcg gtaatccatc
     1561 aaaagaaaaa accaattcta tatttttccc aattgattgt tgagtttttt tccatgtttt
     1621 taaatcttca acggtttgtc tgtctaacga aattatccga atacttgatg tattttttgt
     1681 ttcagcaaat tcataatctt gtcttgtacg gatgtaaatt gacttattta cgctacatct
     1741 gccatttatt aagtcaaagt ctttccattg taacgctaag agctcctcac tccttacacc
     1801 tgtaacaaaa ataaaacgca tcaaacgttt ataaaattct tcataaaaat ccccgtgata
     1861 aacactatta tatactttct taaattcatc aactgtccaa aattctactt gaggacgctg
     1921 agtttttatt ttacctatag tatctacagg attttcttca ataatttcaa gtacaattgc
     1981 ccttttaaaa actactctca acttattgaa tatctgttta atataatttg gtgataatgg
     2041 ttgctcaatg ccctttttta caacatggat tttcgataaa aactgttgaa attcctgtat
     2101 atgaattggt cgaatcttta caacctgcat ttctccaaaa aaatccaatg cacgttgtaa
     2161 aatatgatct gttttcatat atgttttttc tacagttccc aacttatacc aaggaaaaaa
     2221 atactctcga taaaaatcat gaaacgttat tccttgcaga taaattcctt gtgaatcaga
     2281 aaaactttgt tttaactctt cgagtcccct tctagcttct ccttgagttt tgaagcctct
     2341 tctggtcact tgaattcttt ttccaaagcg atcttgtcct aaagttgcag aaaaaaacca
     2401 agtgcctctt tttctgtctt tataaacatt cgcaattttc ctcattttac tattcctccc
     2461 aagaaatatg gagaacttct tctaaaattg aaataggaat tctttttatt tttgaattac
     2521 gataaaaaaa gtatcctttc tcaactaaaa gttctttaca ttccttgaag attttattag
     2581 catagtactg agaaaaacct agattaatca aatcttttcg agtagctgtt ttcattatag
     2641 caccttcctt actttttttc atttatttct atcagctgct tttgtcaaaa gcacatagga
     2701 atttcacctc tccccaagtt tacggcgagc cttacggaag tatcattatc ccaactttaa
     2761 atcatcgctt tttattgact ataaaaatta ttttagaata tttatcgctc cttctttaca
     2821 gcaagaaatc atggcgcaac taaaatatgc tccttaaagt gttaacgtac tgatagaatc
     2881 tatttaattt tcaatgaaca ataggttttc tacctaaaag aatctactaa ttccttaact
     2941 attagaagat tcttttaaac agaaaaagtg gaaaggggat ttttttaatt agttaatttt
     3001 aaattttaag atcgcttcta ttaatttaat ttctagctga cttatcatat attcatctac
     3061 ataggtaacg aattgaccta cctcgttaaa tccatttgtc aaacataact tagccatata
     3121 agaatgataa tgtttgagta tcatcttgat cgaaattgga tctccttcta gagcagataa
     3181 gataatggat agtggaacta ataggtactg ccgcttttta gatttatcta ccataggtca
     3241 taccccattt tcaattgttc aactgccttc tttcgttgat accagatacc acttgtgctc
     3301 atattgagaa ttttaccgat ttcagcatca ttaaaacctg caaaataata aagtaggata
     3361 atctttcttc ttatctccga taactgatca attgctgctg ataacttttg atctgaaatt
     3421 aatatttcca ttccaaataa gaaatagaca tcttgttcat caaaatgagt ttgggaatac
     3481 ctgccttcat ttgaatctgc caatggttcc tcattatcct ttatgttagc gtttcgtttt
     3541 cgaatagact tagcttcgtt tcgtaatact tttttacagt aggcatcaaa ttggtgttgt
     3601 atagatatgt cattgtaatg ttgttgcatg ataatatgct cctttttccc cctttccact
     3661 aatacaacaa tcagaaagcc cctttttttc gaaaaaacta gaaaaaaaac ataaaaatat
     3721 ttatcattct ttaaacagaa aatctttcta taaaaaacaa aaaaaacgat taggctaggc
     3781 taatcgtttt ttgaacattc ttaaaaaatc caaattattt tttataactg aaattgggta
     3841 ttgatgacca tcgtttctgt agatagtaag caatcatttt aggttt
//
LOCUS       DACDLM010000140         3872 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.145, whole genome shotgun sequence.
ACCESSION   DACDLM010000140 DACDLM010000000
VERSION     DACDLM010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3872
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.145"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..132)
                     /locus_tag="IV356_002855"
     CDS             complement(<1..132)
                     /locus_tag="IV356_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAP9016466.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     "
     gene            207..485
                     /locus_tag="IV356_002856"
                     /pseudo
     CDS             207..485
                     /locus_tag="IV356_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific recombinase"
     gene            628..849
                     /locus_tag="IV356_002857"
     CDS             628..849
                     /locus_tag="IV356_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014315041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP9016467.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGNEIKIGN"
     gene            865..1707
                     /locus_tag="IV356_002858"
     CDS             865..1707
                     /locus_tag="IV356_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016468.1"
                     /translation="MKIITINDVEYAVFAANEGTSKPQPHIIETKSGTIPEGKQLSLL
                     KEYLKQNDISPIKGATTYWCIDKVLKLDSSKEKTISETIHKQKYLSLTEENIEKQHKF
                     VGASSNYGKEGLIIHDVLNAFPLHNDLNTIAMKIAVIDVTNSTHLSQYKSRLSLYDLA
                     KVILEIPNFDDRLAKGDPQLINIIARNIGAVNMFSFASKYCTYHNVEVCGRDDYSIFD
                     GIVKNTLPHYIQGLTTNKIDTWRRSFDYEAFNECVGKLLDENNIHIPFRRRKLDHFLW
                     YANR"
     gene            1770..3572
                     /locus_tag="IV356_002859"
     CDS             1770..3572
                     /locus_tag="IV356_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit epsilon"
                     /protein_id="HAP9016469.1"
                     /translation="MGLFDFLKKKQGKVSKHVDYQLASSLFRTGKVFAEKLEVDISNV
                     DEFRKTFIAFDVETTGLNSSSDRIVEIGAVLFKEGVPIQSFGTLVNPKVRIAASASAI
                     NNITNEMLNSAPNEQEVYPQLVEFLGDALDGKITMCAHNASFDFGFLSNTFSRLGYDA
                     KIKYVDTLSLSRKHIKGIVNHKQETVAEYFGLINDTAHRAESDADICGKIFWGVLDII
                     EESLEEQKKQIEKMTPDIKELEACAFIQDIIEKKGCDTSWIRYRKNSNNYVDVTCLYT
                     FLKFKFAKKGNYIIIRKDATNGIDLPIEPCTVSEGGTTNVRVYFRSPFDLTPLSNYIF
                     SAYSDCYNSMNEYMSVSNYTKKEAEQSLSMLKSISKSAMKELLFDAKNRGYDETEVNL
                     NIEKVISREDVIINGLHNRVSLNKIRNIGNWEKGFDAGYPYWERGETARKNGKVDEAI
                     ALFDKARYNGYDAPALYDSYAKAYRKIKDYDNEILILDEGIMRKTRHDVGTLEARRDK
                     AIKLLFAKQEAERIAKEKSDFLKANKKEDAISEPSKKRGRQIIQMTDDGTIIKEFDTI
                     ASAVKEVGVNSKSIRDAANGVQKHAGGYYWKYKD"
     gene            complement(3631..>3872)
                     /locus_tag="IV356_002860"
     CDS             complement(3631..>3872)
                     /locus_tag="IV356_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAP9016470.1"
                     /translation="PPRKNMDKSEKLDHSLLGKQRKTVGTVFSSLEKLGCQNFNSRSV
                     KGLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT         1374 a          562 c          774 g         1162 t
ORIGIN      
        1 atgagaaacg ttaatgccac gatcatataa gatttcttga acttcacgat agctaaggtt
       61 ataacgaaga tagtagccca cggctacaat aatcacatcc tgctgaaatt gctttccttt
      121 aaaatgattc atcgtcattc ctcctgctat ctttttctat tattctacct tatttgatag
      181 tagatttaaa actttgcaac agaaccaaag aactcatcaa gctggctaat aagggtcaag
      241 attatgaaca tctagcagat gagattgatg agctgagaga caagcgacag ctccttttag
      301 tagaagatgc ctccctcagt ggcgagaacg agcgaatcaa tgagctgatt gaatttatcc
      361 gcaagaacaa attccgtacc ttagagtacg atgataagct tgtaaggaag ataatccaga
      421 gcgttacagt ctatgaagaa cacttcgtca tatccttcaa atctggcatc gaaatggaaa
      481 tatgaaaacc agaagtaaat agcccatgat tctacagtag agtcgtgggt tttcttttgc
      541 ttgctgatta taataatatt ttaataacta ttgttattat aaaccaaatg atttataata
      601 ttcttagcgt aaacttggag gtgctgtatg actacggcag aaatgattaa agaactgtgt
      661 gagcaaatga atataagtgt ttccgaactt gctagacgta ttggacagac tccacagaat
      721 ttcaataaga aattacaacg agaaacggta accttagatg agttgaaagc gattgctgat
      781 gtgctaggtg tcaagtttgt gcaggctttt atattgcctg atggcaatga aataaagata
      841 ggtaattagg aggtgtaatt tgtattgaaa atcataacaa taaatgatgt tgagtatgct
      901 gtatttgctg ctaatgaagg tacttccaaa ccacaacctc atatcataga aacgaaatct
      961 ggtactattc cagaaggaaa acaactgagt ttattaaaag aatatcttaa gcagaatgat
     1021 atttccccaa taaaaggagc aacaacatat tggtgcattg acaaggttct taagcttgat
     1081 tcaagtaaag aaaaaactat aagtgaaaca atccataaac aaaaatactt atctttaact
     1141 gaagaaaata ttgagaaaca gcataagttt gtaggtgcaa gctctaatta tgggaaagaa
     1201 ggtctaataa tacatgatgt tttgaatgca tttcctcttc ataatgattt aaatactatt
     1261 gcgatgaaga ttgcggtaat tgatgtaaca aattcaacac atctttctca atataagagc
     1321 aggttgtctc tatatgattt ggctaaagta attctggaga ttccaaattt tgatgatcgg
     1381 ttggcaaaag gagatcctca gttgataaat attatcgcaa ggaacattgg tgcagttaat
     1441 atgttctcat ttgcatccaa gtactgtaca tatcataatg tggaagtgtg tgggagagat
     1501 gattactcca tctttgatgg tatcgttaaa aatactcttc cacactatat ccaaggacta
     1561 actacgaata agattgatac gtggcgaaga agttttgatt acgaggcatt taacgaatgt
     1621 gttggaaaac tacttgatga aaataatata catattcctt ttagaagaag aaagttagat
     1681 cacttcttgt ggtatgcgaa taggtagaat ataagaaaaa ggcatcgtaa aagtgattct
     1741 ggataaaatt aatgggggag gaaataatag tgggattatt tgattttcta aagaaaaaac
     1801 aaggaaaggt tagtaaacac gttgattatc aactggcttc tagtctattt cgtactggta
     1861 aagtttttgc tgaaaaattg gaagtggaca tatcaaatgt agatgagttt cgtaaaactt
     1921 ttatcgcttt tgatgtggaa acaactggcc taaattcttc ttcagataga attgtagaga
     1981 ttggtgcggt gctatttaaa gaaggagttc caattcaatc attcggaact cttgtcaatc
     2041 caaaagttag aattgcagcc tcagcttcgg caataaataa tataactaat gaaatgctaa
     2101 actctgctcc aaatgagcag gaagtttacc cccagttggt agaattttta ggagatgcac
     2161 tagatggaaa aatcactatg tgtgcacaca atgcaagttt cgattttgga tttttaagta
     2221 acacattttc tagacttggg tatgatgcta aaattaagta tgttgatact ctgagtctct
     2281 ctagaaaaca tataaaaggc attgtaaatc ataagcaaga gactgtagcg gaatatttcg
     2341 gattaataaa tgacactgcc catagagcgg aatcagatgc agatatatgc ggaaagattt
     2401 tttggggtgt tttagatatt attgaggagt cgttggaaga acaaaaaaag caaatagaaa
     2461 agatgactcc agacataaaa gaacttgaag cttgtgcttt tattcaagat attattgaga
     2521 aaaaaggatg cgacaccagt tggatcaggt atcgaaaaaa cagtaataat tatgtcgatg
     2581 taacttgtct atatacattc ttaaagttta agtttgctaa gaagggaaat tacatcatta
     2641 ttagaaaaga tgctacaaat ggaattgatt tacctataga accttgtact gtaagtgaag
     2701 gcggtacaac aaatgtgcga gtctattttc gtagcccctt tgacttaacg cctctttcaa
     2761 attatatttt cagtgcttat agcgattgtt ataattctat gaatgaatat atgagtgtta
     2821 gtaattacac taaaaaagaa gcagagcaaa gccttagtat gctgaaatct atttcaaaat
     2881 cagcgatgaa agagttatta ttcgatgcaa aaaatcgtgg atatgatgag actgaagtta
     2941 acctaaatat tgaaaaagtg atatctagag aagatgtaat tattaacggg ttgcataatc
     3001 gagtttcatt aaacaagata cgaaatatag ggaattggga gaaaggattt gatgcaggtt
     3061 atccatattg ggaacgtgga gaaactgcta ggaaaaatgg caaagtagat gaagctattg
     3121 cactttttga taaagctcga tataacggct atgatgctcc tgcgctatat gattcttatg
     3181 ctaaagctta tcgaaaaatt aaggattacg ataatgaaat tctcattctt gatgaaggaa
     3241 ttatgcgtaa aacacggcac gatgttggta ctttagaggc tcgtagggat aaggcaatta
     3301 agctattatt tgctaaacaa gaggcagagc ggatagctaa ggaaaaatct gattttctaa
     3361 aagcgaacaa aaaagaggat gcgattagtg agcctagcaa gaagcgtgga agacagatta
     3421 ttcaaatgac tgatgatgga acaataataa aagaattcga tactatagct tctgctgtaa
     3481 aagaagttgg cgttaactca aaaagtatta gggatgctgc aaatggagtt caaaaacatg
     3541 ctggaggata ctactggaaa tacaaagatt agcagataat ctaagataac ctaggatctt
     3601 cttaatagat acccgtggtg ctagttaatt ttaatatcct aaagaatatc tcaaagttcc
     3661 ttcaaaacgt cgttgtgctc gacttaatag aacactgtaa gccagtaata tgctttcaaa
     3721 tctactctct agccctttaa cagaacgtga gttgaaattt tgacaaccta atttttctaa
     3781 ggaagaaaaa acagtcccaa ctgtttttct ttgttttcca agtaagctgt ggtctagttt
     3841 ttctgattta tccatgtttt tacgtggcgg aa
//
LOCUS       DACDLM010000141         3823 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.146, whole genome shotgun sequence.
ACCESSION   DACDLM010000141 DACDLM010000000
VERSION     DACDLM010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3823
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.146"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            2..550
                     /gene="hslV"
                     /locus_tag="IV356_002861"
     CDS             2..550
                     /gene="hslV"
                     /locus_tag="IV356_002861"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HAP9016471.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            564..1964
                     /gene="hslU"
                     /locus_tag="IV356_002862"
     CDS             564..1964
                     /gene="hslU"
                     /locus_tag="IV356_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HAP9016472.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            1982..2773
                     /gene="codY"
                     /locus_tag="IV356_002863"
     CDS             1982..2773
                     /gene="codY"
                     /locus_tag="IV356_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HAP9016473.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            2855..3730
                     /locus_tag="IV356_002864"
     CDS             2855..3730
                     /locus_tag="IV356_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HAP9016474.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
BASE COUNT         1307 a          663 c          860 g          993 t
ORIGIN      
        1 catggtcgaa tcaccatttc attcaaccac tatctgtgcc gtcgaaaaag acgggaaatt
       61 tgctatggct ggagatggcc aagtaacaat gggtgaatct gttgtcatga aaggcactgc
      121 aaagaaagta cgacgtatct acaatggaga agttgttgta ggtttcgccg gaagtgttgc
      181 agatgcgttt actttagaag aaaaatttga aggcaaacta aacgaatata acgggaatct
      241 acaacgcgca gctgtcgaat tagctcaaga atggcggaca cagcaatcta tgcaaaaact
      301 tgaagcgatg ctgatcgtaa tgaatgataa agaaatgctt cttgtttcag gtacaggaga
      361 agttatcaca ccagatgatg gtatcttagc tatcggatca ggagggaatt ttgcgttggc
      421 tgcagcccga gcaatgaaaa actatgctca aaacgacatg agtgcgaaag aaattgcaga
      481 aaatgcgtta aatattgccg cagatatctg tatctttact aatcataata ttatcgtaga
      541 agaactgtaa gaggtgagta gatatgtatg aattaaaaca aacaccaaga caaatcgtaa
      601 gtgaattaga tgaatatatc gtaggacagc acgcagcaaa aaaatctgtt gccgttgctt
      661 tgcgtaaccg ctatcgccgt ttgcagttag atgaaaaaat gcaacaagat attacaccaa
      721 aaaatatgct gatgatcgga cctacagggg tcggtaaaac agaaatcgca cgacgtttgg
      781 caaaaatcgt caatgcacca tttgtcaaag tcgaagcaac aaaatttact gaagtcggtt
      841 atgtcggaag agatgtagaa tcaatggttc gggatttagt agaaaatgcg atccaaatcg
      901 tagaaaaaga gcagtacagc cgtgtataca caagtgctaa aaaaaatgca gaaaaacgtt
      961 tggtaaaaat cttggtacct ggtatcaaaa aagaacagaa acaatccact aatcaatttg
     1021 aacaaatgat gaatcttttt aatgctagtc agcaaaatac cgctgaaccg caagaagaag
     1081 tgacagaaga tattcgaatc aatcgccgta cagtcttgga acaactacaa aagggtttac
     1141 tggatagtcg tgaagtaacc attgaagttg aagaccaaaa gaaacctgca ccaatgatga
     1201 acaatggatt ggagcaaatg gggatcgacc taaatgaaac tctaggtgct ttgacaccga
     1261 agaaaaaagt ggaacggacg gtaacagtca aagaagcttt agagttattg atcaaggaag
     1321 aatcagcaaa attagtcaag gatgctgata tccatagtga ggcaatcaaa ttagcggaag
     1381 aaagtggaat tatttttatc gatgaaatcg ataagatcac ttctaaatca cagcaatctg
     1441 gagaagtatc cagagaaggc gtccaaagag acatattgcc aattgtcgaa ggttcacaag
     1501 taaacacaaa atacgggatc atccaaacag atcacgtcct attcattgct tcaggagctt
     1561 tccatttgtc taaaccaagt gatctaattc cagaacttca aggacgcttc ccgatacggg
     1621 tagaattaga tgatttgaca gctgaagatt ttgtgaagat tctgaccgaa ccaaataatg
     1681 ctttagtaaa acaatacgtc gcgttgatcg gtacagaaaa tgtgtcagtt acgtttacaa
     1741 aagaagcaat tgaacggatc gctcaaatcg ctttcgatgt caaccgtgac acagataata
     1801 tcggcgcacg cagactgcat accattttgg aaaaactact agaagatcta ttatttgaag
     1861 caccagatat gcaaatggga gaaataacga tcacagaagc atatgtggat gacaaacttg
     1921 gctcaattgc ggcaaatgaa gatttaagtc gctatatttt ataaaaaatc ggaggacgac
     1981 aatgacagac ttgctaacga aaacccgcaa gataaacaca cttttgcagc aaaagaatac
     2041 ttttgacatg caagcagatt tgccttacga taaaatggct gtcacactag gtggtattct
     2101 tgacagcaac acctatatca taggaagtga cggagtatta ctaggttata atgaacgtca
     2161 cgatgtgaac aatgaacgaa tcaaaacaat gtttgttgag aaacaatttc ctgaatctta
     2221 tactgataca gtggcacagt tgatgaaaac tgaagctaat atcccaatta ctagtgatat
     2281 tactgcattt ccggtagagt caagagagaa atatccattt ggtctgacga ctgtcgttcc
     2341 gatctttgga gctggcgaac gtttgggtac gattatctta tctcgtatgg aacaatcgtt
     2401 tgcagatgac gatctagtct tagcagaata tggagctacg gttgtcggta tgcagatcct
     2461 ttatcagaag tctcgaagca tcgaagcaga tgtacggagt gcaacggctg tccaaatggc
     2521 aatcaacaca ttatcttata gcgaattgaa ggctgtacaa gctatctttg aagcattgga
     2581 tggagatgaa ggtcgtctga ctgcttctaa tattgccgat agtatcggca tcactcgttc
     2641 tgtgatcgtc aatgctttac gaaaattgga atcagctgga atcattgaat ctcgttcgtt
     2701 aggcatgaag ggaacttatt taaaagtatt gaattcccgt tttaaagacg agttagcaaa
     2761 acacagttat tagaagtaag gggactgggg cagatagaaa tgtttgttcc agccttccca
     2821 ttttaaaaag taagtcgaag ttggaggaat ggcaatgact gttattattc aaaatgacca
     2881 gctgatcgcc gaaatcgctg aacacggtgc ggaattgatc agtctgaaat caaaagaaca
     2941 tggtttagag tatatctggc aaggtgatcc agcgtattgg ggcagacatg caccggtttt
     3001 attccctttt gttggacgtt taaaagatga tcagtatgtt tatcaaggga aaacatatca
     3061 aatggggcaa cacggatttg ctcgggatat ggattttgaa gtcattgaac atggacaaga
     3121 aatggctagt ttcatcttaa ggagtacgcc ggagacatta gaaaagtatc catttgattt
     3181 tgaattagtg atcagctatg aattaggagg agacggcatc acggttcatt atcaagtggc
     3241 aaataccggt gaaaaagaaa tgttcttttc tatcggtgga catcctgctt tcaatgtacc
     3301 tcttgaagaa ggattgtcat ttgaagattt ctatctggca ttttctccat tgaaatcaag
     3361 attacgccta ccattgaaag gcccattcat cgatatggat caaaagacgt taggtcagac
     3421 aaatacgaat ctggctttga atcgtgaact ttttgagcaa gatgccttgg tttttgaaac
     3481 aaggggtcta aatgcgtacg ccattcgaag tgaaaaatct tcccatagcg taactttaag
     3541 ctataaagat atgccttatg tagggatctg gtctccttat ccaaaagaag cgcctttcgt
     3601 ttgtatcgaa ccgtggtgcg gaatcgctga cacggtgaac agtagtggaa acttgatgga
     3661 aaaagtaggg atcaatcaac taggtgccca tgaaatcttc aagacaaaat attccatcac
     3721 agtgaagtaa gaggttgtga ccgagaagtt agcagggaac accgtttacc aaggtgtgta
     3781 aaaaagctat cctgtaagta ataagggagt gtgacatcga ttt
//
LOCUS       DACDLM010000142         3745 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.148, whole genome shotgun sequence.
ACCESSION   DACDLM010000142 DACDLM010000000
VERSION     DACDLM010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3745
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.148"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..236
                     /locus_tag="IV356_002865"
     CDS             <1..236
                     /locus_tag="IV356_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016475.1"
                     /translation="FLMSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLE
                     YWTYFIGILEGIIFYIGYFPNKNNNFYFYRNKL"
     gene            complement(362..1039)
                     /gene="nth"
                     /locus_tag="IV356_002866"
     CDS             complement(362..1039)
                     /gene="nth"
                     /locus_tag="IV356_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HAP9016476.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(1046..1744)
                     /locus_tag="IV356_002867"
     CDS             complement(1046..1744)
                     /locus_tag="IV356_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HAP9016477.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2012..3196
                     /locus_tag="IV356_002868"
     CDS             2012..3196
                     /locus_tag="IV356_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HAP9016478.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            complement(3202..3645)
                     /locus_tag="IV356_002869"
     CDS             complement(3202..3645)
                     /locus_tag="IV356_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP9016479.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
BASE COUNT          971 a          743 c          621 g         1410 t
ORIGIN      
        1 tttttctgat gagcctgaaa ccgcccaaat ccattagttt atgtttagtt ataaatggta
       61 tttttttatt atcacttatc atttttatta cacctttaga tagatacgtc acttatttat
      121 ataatccttt ggaatactgg acttatttta taggtatatt ggaaggcatt attttctaca
      181 tcgggtattt tcccaataaa aataacaact tttattttta tcgcaataaa ttgtaataag
      241 ttaccatcct agctactgag tatgtacatt tactttttca tgcaaaaaag ataaacgaaa
      301 cagcttttct ccataataac aagataattc atacatttat ttgcaattaa agaaaccacg
      361 tctacaggcg tggtttcttt tttagcgcct tttcttttag acgcatccga tttttcccat
      421 cttgacatat tgatagcaaa ggacatacct cgcacttggg atttcttgcc gtgcaatgat
      481 atctaccaaa aaaaatcagt gtatgatgtg tctttaccca taattcttgt ggtactttcc
      541 gcatcagtgt ttcttctact tccatgaccg tagcatctag tttgcagatc ctcaggcgtt
      601 ttgagacacg ttccacgtgg gtatctactg cgattgctgg tatcccgaat gcatccccca
      661 atacgacatt tgctgtcttt ctgcctacac caggaagaga catcaattct tctcttgacg
      721 ttggcacttg cccatcgaaa cgttcaatca gctgctgtgc acacgctttg atgttttttg
      781 ctttatttcg atacaaacca atcgttttta ttttaagaat gatttcatcg attgaagctt
      841 ctgctaacgc atcgggtgtc ggaaaagagg caaacaaatc tggcgttgct ttattcactg
      901 atacatctgt cgcctgggca cttaagatca ctgcaatcaa taactcaaat ggattattgt
      961 gcttgagttc tccatgtgct tcgggaaaca ttccatacat cgtttctaga gcttccattg
     1021 ttttttgttt gcttaacata ttccgctact cctccaacca atttttcagt gagactttcg
     1081 gcaattcttc ttgttgagct gactgttcta cttctctttg aagaagctgc tgttttcttc
     1141 gtttttggtc ttcttccact tgttgttttg tacgtagatt ttttctttcc cacgatagca
     1201 aaatgcggtc aacgtaatta aaactataag cctgatttaa tacggcttcc cgcagtgcta
     1261 gcttcaaaat ttccggctga taatggtctt cttctagcca ttgtccgatc cgctggaact
     1321 cgatcgaaga aagcgggcgt ccaaattctt gttcaaataa ttgatacact gactggattt
     1381 ctttttcttg tgttttttct tcgtattttt tttcttgtgt ttttaaatac tcacctaata
     1441 gatcatagat ggggtaaaga ttatatcgat ctgctttttt accgttgaca atcgtcgttt
     1501 ctatcttgat aaatccattt gttacgagac gatccagtat ttgaaaaatc tgatcttgtt
     1561 tgattcccat atccatagca atcatctgca aatcagggaa agtatctcct tcaagctgtg
     1621 ccatatgcaa ctgtagaaca aataaaaatt cttcagattg tagaccgatc ctatgataat
     1681 ttttaagtaa aagattagat atgactgttt gtccagcgct taagtaattt tctaaattca
     1741 acatgatttc tcctccgctc aatcacagta tacgtaaaaa aaacatggga agcaagaaca
     1801 ggtttctttt ctatttactt cactgatcgg tcagatttac aatgtcgtct acttgatttt
     1861 tgtttgttca tgtttttgat gcgtatcttc acttttcgga ataaataaat taagtagatt
     1921 tcgctgttcc ttagaatgtt gacaaggaaa caaaattact atacactatt tttgtttcca
     1981 agttaacatt attgcataaa ggagttttta catgtacagt ttcacaaata aacattctaa
     2041 agtttttgga tacgtctctg tcttattcac tggattagga tttactatcg tcagtcctgt
     2101 acttccgttt ttaacgctgc cttattctca ctccatacat cagcaagctt tctatatcac
     2161 tttgctcatg tctgtttatg ctctagctgc cttcttatct gcccccattc tcggtagctt
     2221 aagtgatcat tttgggcgtc atccgatcct tattatcagt ttattaggat caagtatcgg
     2281 atatttgctt tttggtttag gaaattcgat atggatgttg ttccttggtc gtatcattga
     2341 aggattgacg gcaggagaaa tctccacctt atatgcttac tttgccgaca tcacggaacc
     2401 taatgaaaga accaaagttt ttggatggat gggtgcttta gtcggtatag gaacaacgct
     2461 gggtcctatt atagggggtc tattagctga gttggggaat tctgttccta tatttattgg
     2521 agcactcttt actttcttaa atgccgttta tggctacaca tttatgctag aaagccttcc
     2581 aataaaaaaa cgttcagtag atttaagttt ctcccatgta agaccttttc accaattaca
     2641 acaattattc aagatttcat ccgttattcc tttattgaca gcaggttttg ctgtttggtt
     2701 ggcagctggc tctcttcaat ctatcttttc tcaattttcg attgacgcct ttcagtggaa
     2761 ggctgggttg gttggtttaa gcttctcttt gattggaatc ttggatactg tctcgcaatt
     2821 gttcattatg cctcgattgc tcaaaaaatt ttcagaacag cagatcacaa gaatagggat
     2881 gttcagtgaa atcctcgcct atctattcat cacattatct ggaattcttc tactgccgat
     2941 tttgttttta tttgggatta tctgttatgg tttcggtgat tctattttta ctcctgtatt
     3001 caatggccaa ctatccaatt ctgtctcaga taaccagcaa ggtcttgtaa tgggcggtac
     3061 ccaaagtata caatctctat cgcgcgtcat cggcccgcta atcgcaggac agctttatgc
     3121 tgcagcacca tttcttccga cggtattcgg atttttgctt atgatttttg cctattatca
     3181 ctacaataaa aaatagtagc ttcatttgct acttcgtata aattctctgt atcgaccgat
     3241 aaaacgaaat actgtgtcaa attcttcttt tgacatattt tcaaatacag tagcatctcg
     3301 ctgtacccat ttttgatgga gttgctcgtg tctattcctt attttttgtc cgattggcgt
     3361 caattgaaaa tagatttctt ttttattctc ttcgctttga taagtgttta tgatccctct
     3421 agctatcagt ttttttgtta gcttactgat ggctcctcta gtcatgtaac tagcattcgc
     3481 taattttgtc acgttaggat cagggatttt cccgatatgt tcaatcactt ctagttcatt
     3541 tagagtaaat cctgcaaatt ctttttccat ttctggttta ttacgatgaa taatctcatt
     3601 agctaaatcc agatattctt ctattagcag ttgtctttta tccatttcta caccttcttt
     3661 ttctttcatt atattgtttt tttgtttcct attcaacaaa gataaaaata ttttgtagga
     3721 aaacccaatc tgaaaccaag aaaaa
//
LOCUS       DACDLM010000143         3727 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.149, whole genome shotgun sequence.
ACCESSION   DACDLM010000143 DACDLM010000000
VERSION     DACDLM010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3727
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.149"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            477..1517
                     /locus_tag="IV356_002870"
     CDS             477..1517
                     /locus_tag="IV356_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepA"
                     /protein_id="HAP9016480.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
     gene            2341..2673
                     /locus_tag="IV356_002871"
     CDS             2341..2673
                     /locus_tag="IV356_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HAP9016481.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            3292..3633
                     /locus_tag="IV356_002872"
     CDS             3292..3633
                     /locus_tag="IV356_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HAP9016482.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         1372 a          486 c          686 g         1183 t
ORIGIN      
        1 ttaatggtag tacataatta ttatatatat ctgacattgg tagtacttat tgtatttttt
       61 agtagtatat aatctattgt tttctagcct aaagccttgt cttataagaa taatataata
      121 tatactactg aaataaggta gtatatatta ctagtaatgg tagtatgttt tatatgcata
      181 aggtagttct taatttattt tttgttttga cactggtagt acttaattat ctttaatttt
      241 aaaactaaat tttattcata cgtttttctg gtagtattta attataaata atatttattt
      301 aaagtagttc ttaatgactt taaaggtagt acataattca ttttatttct gattttaggt
      361 agtatttaat taaaaaacag ttttaatgcg tttgcatttt ttatttatct ttgctatttt
      421 cgaaaagagt aggtaatttt acataaataa aacaacgtga aagtagagga tctacaatga
      481 ctgattttaa attttttaag gcggatagag tttacaacga attattttat caatttccaa
      541 aagtctttat tgtttctgac gaatacaaaa aaatgaaaga ttcaactaag attgcctata
      601 tgcttttaaa agcaagatta gagatcgcaa tcagcaaacg gcaaatcgat gaagaaggta
      661 atgtttattt tacttatacg acaaatgaac tatgtagagt attaaactgc caaaaacaaa
      721 aagcgatagc aatcaaaaaa gagttggaat cctttggttt attattacaa aagcagatgg
      781 gatttaacaa acagttaggg aaaaataatc ctaatagact atatctagca gaattaaaag
      841 tctcagaaaa tgatatctac ttactcgaaa aatttgatag agagaatagg gaaaacgttg
      901 ataaatcaga gggtatgaaa atcataccca ccctcgacga aaaatcagac gctgaatccc
      961 ttggggctca agagggtatg aaaatcatac cgtgccaaaa cgttgataaa tcagagggta
     1021 tgaaaatcat accagaactt aataataata tattagacac taatagacac aatatagaca
     1081 ctgaaaaaga ccgcctacaa gatcaattgt tgttagacaa ttttgagaca attatgacaa
     1141 acgacagcat tgctacgttt gtccctgaac gagtattaaa tttgataaaa acattttctt
     1201 caagttacag tgaagctcaa aaaaccgtcc agactattca taatgcaaag aaaaaagctg
     1261 aaatagaaag tgatatttcg atagtttttg aagaactcga tagttattat gtcaatgcag
     1321 aacaagaatt atacacgaca ctgttaaaag cctatcaaaa attaaaaacc gaaaaagtcg
     1381 aaaatatcca gaacctgatt tttgtctatg taaaaaattg gtttatcgaa aaaccaatag
     1441 ctgctaaagt atcaagtgaa aaacgtttga attatgcaag ctccccaagc actattacga
     1501 aagactggtt agagtgaaac tttactgaca aagtgattgt tgcttcatgg agtaacatta
     1561 aaattaaaaa ttttttatta ttctaattat attacgaata ttacaaaata atagctattt
     1621 taatagaatt tataagttaa aatattatga taaaaatcac aaacgtagcc ttttacgtca
     1681 taagtgttaa aagaaataat taatttcaaa tatagaaaag ggaacgtatg tttgcatact
     1741 cctttttttt gagttataat aatacgcgaa gagagataat ttcattattt aaacaagcta
     1801 aaaatcttga tattacttct tttcaggcaa tacgaatatt attcgcttac attttttgta
     1861 taaatttaat tgtctgctat gcttgtgatg aattgatttt cgttttgcac ttttggatga
     1921 taaatttgga caattgaaaa tacaaaaaaa agaaaggcgg tatgaactcg gaaggctggt
     1981 aaccttcgtc agcgttcata cacggcatta agatttggcc cttaatgcgt taacctttca
     2041 gtgttacggt attacccgca atggatttag tataacagat attcaaaagt gataccactt
     2101 tttttggctg tgttaaggtt aaaaatacgt gatattacga tgaatctatg cctaagcata
     2161 atgttataaa aatgtccgtg tggctctttg ccgtatgacg aacgctgaaa ttagagggaa
     2221 cgcatgtttg gatgcgttcc ctcttttttg tttgtcatga acgaaaatca attctctatt
     2281 tttgaaaaat aacaagaaaa acttgttaaa aatatttaaa gaaattgggt ggtttatttt
     2341 atgtcatata caggaatttt gagtctcaaa gatatttgtc actacggtaa acggtgtacc
     2401 gctacagaga aaatcacgaa gaaactatca actggccaaa gtaaaaccgt tgtgcagtgt
     2461 aagaaatata taatccagaa agacaaagtc tcagaggaaa tgatttatta cattgggaaa
     2521 caaaagcaaa taattttaaa agatcctatc cccttaaaag agctatatcc aacaatcaaa
     2581 catgtttatg accaaaacgg tgtactgatt ggtcgaagaa aaaatggagt cttgcgttgt
     2641 accgcaaaag ggatggggcg tttgatcggc tgaattgatc attctcataa cttgtatttt
     2701 atcgtttttc gcttgcttga aaatattgtc gagacttcta aaggaactta gagtcactag
     2761 aaaaataagg agtagacttg atctatcaac aattcccttc ggggagtgac ggggtaggtt
     2821 ttaacgattg gtaacgtaaa aaattggtca atcgagtaaa tgcgcttgtt tggatagtgg
     2881 tgaaatgaat ttgtgtaaat aataagcgca gagtaaacaa gagggaattt agaagttaga
     2941 caagttagaa tagcgtctag attaatcatg agcagctact aagggatcta gactttgacg
     3001 caaactcatg gaataaggag taggtcttct cgtaatgggg aggacgcaca agaaattgtg
     3061 tcgtgtgctg cagtacatgt agatacttgc gaggacgttg attattggat caatcgagca
     3121 tttaccgctg tctactaggg tttctcgttt cggacgccat aaacgagtcg aaatttttta
     3181 tgtattttta agtaaacgaa aaacgataaa atatgaacaa gtcctgaata aagtgaaaaa
     3241 attaatataa agcatagaga aaatgaaatt tacgtaatgg aggaatgaca aatgaaaaat
     3301 tatgatccga atatacgatt gggcacacat actattaagg tttctttcca acgttgggat
     3361 tacaaaggat ttgtgacgtt tagaaggggc ggaaattgta aaggattaga tgttttagca
     3421 ttagacgagg atgatttata cgatcaaaca ttgactgata atccaattgg attcggcttg
     3481 ctacctgaag atgatgaagg taatgaatgg tttaaaatga cgcttatgaa tgataatgga
     3541 gacgaattat ctgttgaaga tacttggtca tatttgagtg attatattgt cagctttgaa
     3601 atcattgaat ttgtagcgga taaagaagaa taaaaactgg aggaataaat tttacagata
     3661 aaggcttaga aggagtcacg acgattaata aaaaggtagt attaccttag gcattgagta
     3721 aggaatt
//
LOCUS       DACDLM010000144         3721 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.150, whole genome shotgun sequence.
ACCESSION   DACDLM010000144 DACDLM010000000
VERSION     DACDLM010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3721
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.150"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            260..1450
                     /locus_tag="IV356_002873"
     CDS             260..1450
                     /locus_tag="IV356_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HAP9016483.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFNGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKEVALEARGTFAEKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
     gene            1584..>3721
                     /locus_tag="IV356_002874"
     CDS             1584..>3721
                     /locus_tag="IV356_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP9016484.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILLDDSYYYSSKTLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNS
                     ESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDY
                     EFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVY
                     VDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIG
                     ENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIY
                     LALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVH
                     LAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNG
                     LLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRI
                     QRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEI
                     EFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGKGW
                     FAIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSSLSA
                     SLKTSDTADLNIAIISLLEYFGKDEDVVYL"
BASE COUNT         1302 a          594 c          680 g         1145 t
ORIGIN      
        1 aatttttgca cctaatcata ctctgtttat atatgaaaac tagattctga atccaatatt
       61 tggttaacga gaggcgttcg aatttgaacg tcttttatat attactttca aataaatatg
      121 aggtagaata ctatctattt tctttttaac ccaattgtta taatggagag tgtaaaatat
      181 tttgtgtaaa tagaaaaaag gaagtccctt ctgtagaata gagttaccac aacacattca
      241 cagaagagag gacttcccta tgaacgattt tactacagaa attctaaaga ctctagcgaa
      301 caaaggcgat ttgaatgaat tattccgtgt ccatttggag aaagcagtca atacgcttct
      361 caaaacggag ttaacggctt tcctagatta cgaaaagtat gatcgcattg gttttaacac
      421 gggtaattct cgtaacggct cctatgaccg tacggtcaag accgagtatg gggaacttca
      481 tctccagatt ccgcgcgacc gcaatggtga gttcaagcaa cagactgttc ctgcttatag
      541 acggacgaat gacacgttag aggagaccgt cattcacctc ttccgaaaag gtattaccat
      601 gtcggaaatc gcagacttga ttgagaaaat gtatgggcat tactacacgc cccaaaccat
      661 gtccaatata acaaaatcat ttacagaaga ggtaacggcg tttaatgggc gggagcttca
      721 tgaccgttat gctgctattt atatggacgc aacgtatatt ccgttaaagc ggaaaaccgt
      781 cgccaaggaa gctattcata tcgcagttgg cattcgcccg gacggatcaa aggaagtatt
      841 gagctatgcg attgcaccga ctgaatccat cacgatttgg gaggaaattt tattggacct
      901 tcaagagcgc ggtttgaaaa atgtcctcct gttcatcacg gatggcttaa aggggatggt
      961 aggagcgatt agtcggttct atcccaaagc tcgttttcaa cattgttgtg tacacgtttc
     1021 ccgtaatatc agtcataaag tgcgtgtcga tgatcgtaag gaagtctgtg atgattttaa
     1081 aatggtgtat caagcctcat ctaaagaggt ggcgttggaa gcacgtggta cttttgcgga
     1141 aaaatggaaa accagctatc caaaagtggt tgaatcgatt ctttcgaacg atcacttgct
     1201 cactttctat gatttcccct tggccatacg caagagtatt tattctacga acttgattga
     1261 atcctttaat aaacaaatca agaaatacag ccaccgcaag gaacagttcc aaaatgaaga
     1321 gtcgatggaa cgtttcttag tctcgtcttt tgatacttac aaccaaaaat tcctaggtcg
     1381 cagtcataaa ggtttccaac aggccgaagg cgagctcgaa caaatgctaa gccaactgat
     1441 tgagaattag aaacaatctg cagtagggaa gaatcattta cacaaaatta ttgacgctcc
     1501 cttataatga gaacttttac taacataatt tatgataaac ttactatata atcatattaa
     1561 ttaaatagtt aggagatctg cttatgttta tatctactct tcaaattcga aattttagaa
     1621 attatgaatc cgaaatcttt cgattcgata atgagacaaa tactattata ggtgagaatg
     1681 attcagggaa aaccaatgct cttactgcat tgagaatctt attagatgat agttattact
     1741 atagtagtaa aacactaaaa gaatcagatt tttttcatgg aattcaaaat gggtggcaag
     1801 ggcattggat tattatctct gcgacatttg aaggaatcag cgaagaagaa tttgacaatg
     1861 agatttgtgc ttccatttct ttaaattctg aaagtcaaac aatcttagaa gaattgattt
     1921 caaatgcaga taaaggtgta ggtagtattt ctctatttat tagacctaac aaagctatta
     1981 gaaagcaatt atttgatatt tccactgaat tagactctca tcaatttaac gaatttagaa
     2041 attctattcg tctatccgac tatgaatttt actacacatc taaatcaaat ctaaatttct
     2101 gtatcaatga aaattatgat aaattggtag gaagactcaa tgacaatata gctagtaatc
     2161 ctgaagaaga cgatgaagct ctgttgggct caagaattga catgtcagat attttcaagc
     2221 atatttcggt tgtttatgtt gacgctcttc gagatgttct tagagaaatg aaaaacaatc
     2281 gaaacccagt caaaagaatc atggaaacaa ttgaatcaaa aatatcatca gataatgttg
     2341 agtcattaaa aacaattata cagcaattaa atgagactat taccagtgtt cctgaaatta
     2401 ggaaaattgg cgaaaatatt aatcggcaac taaatagcat aattggttca gtgtattctc
     2461 ctaatcttct tctttcctca actatgtcag atgatatggg ttctttagca aaatttcttt
     2521 caatgaagcc agaacaaaat atcgacttag acttactagg gttaggacat ctaaatatga
     2581 tttatttagc tttgaaaata gtcgaatttg aagcgtgtcg ttcaagagaa ctacttaata
     2641 ttatgttgat tgaagaacca gaagctcata ttcatcatca tattcaaaaa actctgttcg
     2701 aaggattaaa tcttcaaaaa aactatactc agattctcat gaccacacat tctgtacatt
     2761 tagctgaagt gtctgaaata tctcggatga atgtattaaa atcgtttaat ggcaaatcta
     2821 tcgttatgaa tccagcaaat aatctgaact catttgctaa agaaaagtta aaaaagaaca
     2881 atctaaatct aataaacgca gtagagagat atttagatgt taaaagaaat ggattgcttt
     2941 tttctaaagg tgttatctta gttgaaggag atgctgaaga aatacttatt cctcaaatag
     3001 taaaaaaatt atttggtata aacttagacg aacttggaat aggtttgatt aatgttggta
     3061 gtacttcgtt tgaatatatc gctagcttgt ttgacgatga tagaatacag agaaagtgtg
     3121 ctattgtaac tgatttagat gaacaggcaa tcccatcaga acatcgattg tataaaagca
     3181 ctgcacaaga gaaaggtcaa gcaagaaaag aaaaattatc ctcccttttt aatgaaaaca
     3241 attgggttaa ttgtttttat gctaatacaa catttgaaat tgagttttta gatgtgaata
     3301 aagaaaatat tctaacttat gtcagtccaa ttatagatga cgcattcaaa gataaaaaaa
     3361 caataactgc ttataaagaa gaaatacaaa gtgaacaata tttagaaaga aatttagcga
     3421 tgttaaaact agccaatcat gttggtaagg ggtggtttgc aattgagtta ggtgaaaaaa
     3481 ttgacttttt aatcaaaatt cctaagtata ttcttaatgc tattgctttt gcatgtcagg
     3541 aaatagtaga tctctcaatt tataaaaaaa ttctactcca tacaatcgac ttgtacgagg
     3601 aaactacaga attgtcatct ttatcagcta gtttaaaaac aagtgataca gctgatttga
     3661 atatagcaat aatttcttta ttagagtact ttggtaaaga tgaggatgtt gtgtatctaa
     3721 t
//
LOCUS       DACDLM010000145         3371 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.151, whole genome shotgun sequence.
ACCESSION   DACDLM010000145 DACDLM010000000
VERSION     DACDLM010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3371
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.151"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            298..2037
                     /gene="yfcC"
                     /locus_tag="IV356_002875"
     CDS             298..2037
                     /gene="yfcC"
                     /locus_tag="IV356_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HAP9016485.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            2194..>3371
                     /gene="iadA"
                     /locus_tag="IV356_002876"
     CDS             2194..>3371
                     /gene="iadA"
                     /locus_tag="IV356_002876"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HAP9016486.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     "
BASE COUNT         1074 a          550 c          772 g          975 t
ORIGIN      
        1 ttattttttt tgcaatgaaa ttcaattttt caatgattgt aaaatgaaaa aaacaggacg
       61 agattttctc taatctaaaa ataaaaaaag aattttaagg aaaaacagag aaataaaata
      121 cttaatataa atggaaagag aaaaaaataa tcatacatag gagaaaaaaa acaaaataga
      181 aaaaagtgat tttctaataa attattcatg tggaaatgtc atttttactg tataattcat
      241 ttgattatcc attttttatt catcaaaatt actgaaaaaa gaaaggaaga aataaatttg
      301 aagaaaacaa attcttcagg aaaaccgaaa cgcgacttca ctaaattatc gacaccccat
      361 acgtatgtca ttatttttgg tgtagtcatc tttgcatgga tactgacttt tgtcgttcca
      421 gcaggaaagt tcagcacgca agatattgaa tacaaagatg caaatggcga aacaagtact
      481 cgtactgttt tacgtcaaga ttccttccgt tatgcttacg agctggataa gtcgtatgtg
      541 tttgatcaat tagaagaact gcaagatcat ccagcagaac gtgaaaaact ggatgttccg
      601 gaaaaaggat tggaaaaagt cattgctgac ggagaaaaaa atcttacgca ggaaaaacta
      661 gatgaaatct ccttgacaga tgatgtgctt tacgatcagt acggcgaaaa tatctatgat
      721 acttctaaaa aattgcataa aacagccaaa atatggggaa cagatgattt tggcggcttt
      781 ggtttcttaa attttgtttt tgaaggacta gtatctggag ataagtatgg atctgctgta
      841 gggatcgctg cattgatcct tgttgttgga ggtgcttttg gtattattat gcgtaccgga
      901 gcgatcgacg caggtatcta tgcgtttatc agtaaaacta agggactgga gcgtttagct
      961 ttaccgctat tattctttgc tttttcattc ggtggcgcta cattcgggat ggcagaagag
     1021 gtaattccat tctcaatggt gatggttcca tttgtcattg cgttaggata tgactcgatc
     1081 gtagcagtaa ccgtgactta tgtcgcatct caagtcggaa atgcgacctc ttggatgagc
     1141 ccgtttagcg tagcggtggc tcaagggatt gctggaatcc ccgtgttgtc tggtgcgaca
     1201 ttccgattga ttatgtgggt agttgttact gcattagccg ctggttatat gatgatatat
     1261 gcagaaaaaa tccgtaaaaa accagaaagt tcgttgactt acaaatcaga tgattatttc
     1321 cgttctcata tcaaaaagac atctgatgaa aataaaaaat tcatgcttgg gcataaattg
     1381 atcttattag agatgttagt tgtccttgtc tggatcgttt ggggcgtgac tcaaaaaggc
     1441 tattacattc cagaaatcgc ttctcaattc tttgtgatgg gattagttgc tggaatcatt
     1501 gctgttcttt tcaaattaga tggaatgaaa gtcaatgaca tcgcttcttc tttccaatct
     1561 ggtgcagctg atttagctgg tacagcaatc gtagtaggta tggccaaagg gattcttctt
     1621 gtcttgggag gatctgatgc atctgttcct tcagctttga atacgatttt gcatgggatc
     1681 gggacggcgt tgaccggtgt tccagctgtc attggtgctt gggcgatgta catcttccaa
     1741 agtttgttca acttggttgt tacatcaaat tcaggacaag cagctttgac tatgccaatc
     1801 atggctccac tggcagattt agtaggtgta tccagacaag tagcagttct tgcttatcag
     1861 cttggttcag gttttatgga cgcttttaca cccgtatcag ccagcttgat tggtgtgcta
     1921 ggtgttgcac ggatcgaatg ggcaaaatgg gcaagattcc aaatcaagat gcaaggattc
     1981 ctgtttgttt taggaactat tttcatcatg attgccattg caataggtct gcagtagtac
     2041 tggagacctg taaataaaaa agtaatccaa acagtagata aggactccaa gaaccgtcat
     2101 tttacggtaa aatcaaagga gtaaagatcc tatcgtttgg attatttttt aagatcctat
     2161 catcagttat acttaaagaa agaggaaaaa tgtatgaaaa tcattcgaca aattgaagtg
     2221 tttgcaccag attacttagg aaaaatggat gtactgattg ccggtgggaa gattttggct
     2281 gtagaagaac agctagaagg cggctacgaa ggagtggaag tagaagaact ttcaggtgag
     2341 ggaaaagtac taaccccggg tttcattgac tgtcatttcc atattttagg tggaggagga
     2401 gaaggcggtt atcaaaatcg aacgccagaa gtcacattga gccaattgac tacagctggt
     2461 gtaacgacag ttgtcggttg tttgggaaca gacggagaag gtagagatat gactgcgttg
     2521 atcagcaaag cgaaaggtct ggaagcagaa ggaatctcca cttatgtata cgaaggttcg
     2581 taccgattgc cggtaaaaac agtaacagat tctatcatca aagacttttt gacaattgat
     2641 aaaattatcg gaatcggaga aatcgcagta tccgatcacc gttcttctca gccaagtttt
     2701 gaagagttcg ctcgtgcagt agcagatgct cgtgtaggag gcatgttatc cggaaaagct
     2761 gggatcatca atgtccactt aggcggagga aaaagaaagc tagagctatt gacacgaatc
     2821 gtagaagaaa cagaaattcc gatcacacaa tttttgccta ctcatgcaaa tcgcacacca
     2881 gaattatttg aagcttgcgt ggcatttgcc aaacgtggtg gcacgattga cttcactgct
     2941 agcgaagatc ctgatttttg ggagaagaca gatggtgaag ttcgcttcag caaagcactg
     3001 aaacgattga tcgaggaaga tgtttcttta gataatttca cgatgacctc agatggacaa
     3061 ggaagcttgc cttattttga tgaaaacaat catttcctag ggttaggagt aggaagtgcc
     3121 aaggcattgc tagtagggat caaagaagct gtgcaaaaag aaagtatccc tttggaaatc
     3181 gccttacgag ctataaccag taatccagca cgtatattga aattggataa aaaaggaaaa
     3241 atcgaaattg gtgctgatgc agatctgtgt atcttggata aagaaacgct tgatattgat
     3301 acagttatcg ctaaaggaga aataatggtc caagaaaaag aagtcaaagt atgggggact
     3361 ttcgaaaaaa g
//
LOCUS       DACDLM010000146         3303 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.152, whole genome shotgun sequence.
ACCESSION   DACDLM010000146 DACDLM010000000
VERSION     DACDLM010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3303
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.152"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..2232)
                     /locus_tag="IV356_002877"
     CDS             complement(<1..2232)
                     /locus_tag="IV356_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016487.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
     gene            complement(2904..3172)
                     /locus_tag="IV356_002878"
                     /pseudo
     CDS             complement(2904..3172)
                     /locus_tag="IV356_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT          900 a          741 c          536 g         1126 t
ORIGIN      
        1 accggtttgt agcgtttctc cttctcggtt ctgtaactca aaaacagctc cttgaaggac
       61 ttcaccactg ccttcagcat gtttaattag ttcaacacca cccgtatcaa ggatgttttc
      121 aatggttaac gtcacttctt ctatggagta ttcatttata aaaacatcat gtaccgtcgc
      181 atctaaaaga tacccttccg gtgcttctgt ttctcggact tgatagctac ctacaggaag
      241 cggttcactt aaaaattctc cgttttctgc cgttatacct tcttgtatca cttgtgaatc
      301 gcttgataaa atttcaaatt ttgctcctgc cagcctttgg ccattctcat cagttttaat
      361 tactttaata cgcccatcga ttttccttgt tcttacagta ctcgtattca atcgattgtc
      421 actattcaca agcgttgcaa agtttaaaat ttgatcgccg accgcatacg cctctacatt
      481 gaccttaaaa gagagggtaa aacttgtcgg accaccaatc gtattattcg cactgaaacg
      541 aactattcca ttattgactt cggcatcaat gaaagaggga atatctgata gaaatgacac
      601 aaattccatg ccttcttcca aaacatcttc aataacaagc gtatttcttg ttccagaaaa
      661 catcgagaca tgcagagtat acgttagttc attttcattg agattgataa catttttgtc
      721 cacacttttt cttaaagaga ttgccggaag attactttca gggattctca agcggtagtc
      781 tcggctcatt acctgattat tgtaggtcat actcgctcga ttccgagaaa acccatcctc
      841 ttgtcttcct tcattgaaca agtcgacatc ggtcacttca agagcatatt caataaaata
      901 cgattgaccc tctgctagat taccaaagtc cacaacaagt gtattcgttt ccttattaaa
      961 agatactttg tccacaaatt cctcggaaac ataatgagtt ctaacgtttg cttcacctgg
     1021 attcgttact tctgcgatcc gaaccccacc tgaaataggt tctctatttc cagtggaact
     1081 ccatgtagtc ggattcggtg ccaaagttgt tccttgcggt agtacatcgg taaccactac
     1141 accgtctttt cgtgatcctt cataatttac ctgcaaaata aatttattac tgttggtcac
     1201 gtcttgcccg tcaatcagca gattcccaag atttccttgg ctgtcgattt ctctagagcc
     1261 atagtataat ttcgaaaaaa tgggtcttga tgaaggaata ggcgtaattg aaaattccgt
     1321 gtttgctgct cgctcagcat aagtaagact cacttgaaag tcattatttg gctcagtacc
     1381 gcctgattga aagaaagcaa cttcaaacgt gatactgaat gtatacgact gagcggcttc
     1441 atttaatcct tcataatcaa aggtaaatgg aaaaacaacg tctgtgcctt cttggtaaaa
     1501 tgccagtggc tttaaaggtg aatcatcagc gacctccact ctaatgaact caattaagcc
     1561 aatcgatgct ctaggaactc gtacgaccat ctccccatat tcttcaagaa tatcgccagc
     1621 gcctccttga atgtatccct ttaacgtttg tgtatgcctg ctcggcaaag tggggcgctc
     1681 agcagagatg ccgatgtcat aattcaagag ctcctcttgt ctttcaatct gagattcctg
     1741 cgttatagat ggctcagatg atctggcttc attaaaagat tcacttaagc tttcttctgg
     1801 tatattaaaa gattcacttg tgctttcttc tggtacatta aaagactcac ttgtgctttc
     1861 ttctggtaca ctgatttcta ttgagaccgt atttgattga atatcaccgc ttcttgcggt
     1921 caattcgtat ttacctgaat gctgggaaga ataagtaatc agacgttcgt aatcattgag
     1981 ttgcttcact tccccttcaa tcaaatcctc actcttatca atgaccaatg catttagcag
     2041 gtctggtgtt cctctgactc gcaactggaa ctgctcaccc aaagcagcct cctcttgatc
     2101 aacttcgatc gtcagcgaac gctctggctg ttctgctaaa gactcagcta gaaccgttat
     2161 gttcccaaat tgattgatca caataagcat aactagaaac atacttaaca gtttatgaaa
     2221 tttgttcctc actattactc ccccttataa ttttgactaa acaacaaggt acccgataat
     2281 tttctaaaaa gattccccaa ctcaaaatgg ctgcgttacc tccctcgtat tttcggttca
     2341 actcaagcgt tgcaatgtaa gctgtaaaca aagctaatga ttgccgattg tcttctgttg
     2401 attgattcga tagctttgta tgacttttag ttgtccgtgt ggcttaacca taattatgat
     2461 ttcacgattc ctcctgccag tgccttgcac aagctggagc gtaaccctaa tagttatttt
     2521 gttaatgtac ttatatactt ttatactttt ccattagaaa caatcactaa atcgttgata
     2581 ccaaggtcag actctagaat ttcatcagtg agtccctgta ttggttaacc ttcatcaatc
     2641 ccaaaaaaat atatcaatgc ttagcatcaa aatgaatata tagtttagaa tacttgggat
     2701 tcatcgataa ctgatcgctt atttggccat attatttggc acttggttca actaaacgca
     2761 tttaggatgt tccttcattc tcgtcatgga tgttctcaaa ccgtcattac taataaactg
     2821 tccaccgaat cgatggttca tttcttgcat tttccacgtc caattactct ttttgctctt
     2881 tatttgggcg tagtttcact ttcttaactt gtatcgtctt ccatcaactc cttaatcatc
     2941 ttcttagctt tattggctcg gtttccttgt aaaaggtatc tacaaatagt gacaatctgt
     3001 attaaatctt catcattttc tgtaatgtca ataatttcta tattctgtac catatattgc
     3061 aaagggtttc actaagttca taaccgaagc gaattaaaca acttttgtat agaataacta
     3121 ccttttctat ttttccattg gtaattctat ctattaattg gtttaatcct tttgttgtag
     3181 ttgattccac taccaagatg attctctcga attttaaagc ttgaagatgt attgctattt
     3241 ttgctaactg gcgtatttgc aactattttt cccttctatt cttccttcat tgattcccct
     3301 cta
//
LOCUS       DACDLM010000147         3293 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.153, whole genome shotgun sequence.
ACCESSION   DACDLM010000147 DACDLM010000000
VERSION     DACDLM010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.153"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            236..1627
                     /locus_tag="IV356_002879"
     CDS             236..1627
                     /locus_tag="IV356_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAP9016488.1"
                     /translation="MNKNGEWNAARRIFIILMDVLVLNVSIYLSFLLKFQGEVPVRNL
                     ETFQHSAIFISIIFIALNILLGAYVFYNRMISDIVFITVIGQVLIALGIMVVTFAGRW
                     FAFPRGVILISFILGTILLSVYRIVVYKLYLRVSRDKKVLIVGLEKDVAPAIQNFQSK
                     KNNKHKVEAVAIDNYYENTKKLIDDMDIVYLASKIPEDEKINIYQLVTKKEKKLFLNT
                     TFENLTMINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLILLILASPFMLIT
                     AILVKTTSPGPIIYKQVRITKNQKEFSIYKFRSMSATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNEENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLLLDLKILLQTIKILFDKMSSQGLDEDENISS
                     LAESAFPKEKTYR"
     gene            1665..2495
                     /locus_tag="IV356_002880"
     CDS             1665..2495
                     /locus_tag="IV356_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP9016489.1"
                     /translation="MENKNISILLSLYDKEKPEYLKEALASIFEQTVMPAEIVLVYDG
                     PINEKLQAVVTYFQQKVPHLFTVVKLEKNQGLGIALATGLEHTKNRLVARMDTDDIME
                     PHRLEKQLEIFQEYPEIAIVGSNIEEFTGTLSNVIGRRIVPEYNDEIRVFSKRRNPFN
                     HMTVMFDKNAILEVGNYRPLIGFEDYYLWVRLLKAGYKGYNIQEILVHARAGADMYAR
                     RGGSKYLLPGIKGRYRVWKDGLGSLKDFLIVICGHLVISLLPNKIRGKVYESKLRKTN
                     "
     gene            2467..>3293
                     /locus_tag="IV356_002881"
     CDS             2467..>3293
                     /locus_tag="IV356_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP9016490.1"
                     /translation="MNQNLEKQTKLSIIIPFYNAKNTLRRAVDSVLTQGYPNIEILLI
                     DDGSTDGSSDIGDEIANLESKVACYHLENAGPSVARNYGIKEATGNLVGFLDSDDYFL
                     PDCFNNVLKDYHRNHPDIIAFGLSKGKNIENANLFVPEKKIGCSSEEAIEQMFRSKAV
                     DFYVWNKFFKRELFNHIVFPENKLYEDMVPMYEAFRAASKIDILPFSGIFYYQNNDSI
                     VYQSFNSKQYDNILQRKILVDEVKKDYPRLINLANARLVDGYLSTGFKITGKNQNQK"
BASE COUNT         1151 a          462 c          640 g         1040 t
ORIGIN      
        1 tatgaatatt gtaacttgtg aataaggaat tagcaggaga atactagttc agcataaagg
       61 aagtgatggg acttctgaga caactttctg ttatgcagaa atacacatat aaacagacaa
      121 taaacgcttt tccccgtttc ttttaatttc ctttacaatt tggttattca ctaggttttt
      181 aaactttgct atggtaagat gatagaggca ttattttatg gttaggagtg tatatatgaa
      241 taaaaatggg gagtggaatg cggcacgcag aatattcatt attcttatgg atgtacttgt
      301 attaaatgta tcgatctatc ttagtttttt gctgaaattc cagggagaag taccagtgag
      361 aaacttagaa acctttcagc attcagcaat ttttatttcc atcatcttta ttgcgttgaa
      421 tattttgtta ggagcttatg tattctataa ccgaatgatc agtgatattg tcttcattac
      481 tgttattgga caagtactaa tagcattggg gatcatggta gttacttttg ctggccgatg
      541 gtttgcattt ccgcgtggcg tcattttgat ctcgtttatc ctaggtacga tattacttag
      601 tgtttaccgg atagtcgttt acaaactgta cttaagagtc agtcgtgata agaaagtcct
      661 tatcgtgggt ttggagaaag atgtcgcacc agctatccaa aattttcaat ctaagaaaaa
      721 caataaacat aaggttgaag cagtggcaat cgataattat tacgaaaata caaaaaaatt
      781 gatcgatgat atggatatcg tctatttggc ttctaaaatc ccagaagatg aaaaaatcaa
      841 catttatcaa ttagtgacta aaaaagagaa gaaattattt ttaaatacga cttttgagaa
      901 tctgacaatg ataaatccga atattatgaa ttttgaagat gaaagcatca ttgaagcttc
      961 tgggttcaga atccaaccag aatacgaact attcaagcgt ctctttgata tcatcgtttc
     1021 gcttatttta ctgatcctcg cctcaccttt tatgctaatc acagcgattt tggtaaaaac
     1081 aacttcacct ggaccaatca tctataaaca agtacgtatt acgaaaaatc aaaaggaatt
     1141 ttcaatctat aaattccgtt ccatgagtgc gacagctgaa gcaaaatcag gaccagtctt
     1201 ggctaaaagt aacgatgcac gtgtgacacc agtaggtaaa tttatccgtg ctgtacgttt
     1261 tgacgaatta cctcaaatct ttaatgtatt gaaaggcgat atgtcgattg tcggtccaag
     1321 gccagaaaga ccatttttcg ttgatcagtt caatgaagaa aatccttatt attacttaag
     1381 acacaatgta cgtgcgggaa ttaccggata tgcacaagta tacggaaaat atgtatcaga
     1441 ttataacagt aaactacgtt ttgatttgtt gtatatcaaa aagtattcct tactattaga
     1501 tttgaagatt ttacttcaaa caatcaaaat cttatttgat aagatgtcct cacaaggact
     1561 agatgaagat gaaaatatca gttcattagc agaaagtgca tttccaaaag aaaaaacgta
     1621 tcgttagatt ggaaaaattt tgagcaaaga agtaggagag aacattggaa aataaaaata
     1681 taagtatact gctttctttg tatgataaag aaaagccgga atatttaaag gaagcattag
     1741 ctagtatctt tgagcaaacg gtgatgccgg cagaaatcgt attggtttat gatggcccta
     1801 taaatgagaa gcttcaggca gttgtcactt atttccagca aaaagttcct cacttgttta
     1861 cagttgtaaa attagaaaaa aatcaaggat tggggattgc tttagcaact ggattagaac
     1921 atactaaaaa tcgcttagtg gccagaatgg atacagatga catcatggaa ccacacagat
     1981 tggaaaaaca attagagatc ttccaagaat atccagaaat agcgattgtt gggagtaata
     2041 ttgaagaatt tactggcaca cttagcaatg ttatcggaag aaggattgta cctgagtata
     2101 atgatgaaat ccgtgtgttt tcgaaaagaa gaaacccttt taatcatatg acagtcatgt
     2161 ttgataaaaa tgctatttta gaagtgggaa actatcgccc attaattgga tttgaagatt
     2221 attatttgtg ggtaagacta ttgaaggcgg gatataaagg atataatatc caagagattc
     2281 tagtacatgc tagagcaggt gctgacatgt atgctagacg tggaggaagt aaatatcttt
     2341 taccaggaat taaaggccga tatcgcgtat ggaaagatgg tctaggatca ctaaaagatt
     2401 ttctgatagt tatttgcgga catcttgtaa ttagtttatt accgaataaa attaggggaa
     2461 aagtatatga atcaaaactt agaaaaacaa actaaacttt ctataatcat acctttttac
     2521 aatgcaaaga atactttaag aagagctgta gacagcgtct taacgcaagg ttatcccaat
     2581 attgaaatct tgttaattga tgatggatct acagatggta gtagtgacat tggtgacgaa
     2641 attgctaatc tagagagtaa agtagcatgt tatcacttgg aaaacgctgg tccatcagtt
     2701 gctaggaact atgggataaa agaagcaact ggaaatttgg taggattttt agatagtgac
     2761 gattattttt tacctgattg ttttaataat gttttgaaag actaccatag gaatcacccc
     2821 gatatcattg cttttggatt aagtaaagga aaaaatatag aaaatgcaaa tttatttgtt
     2881 cccgaaaaga agattggttg ttcaagtgaa gaagcaattg agcaaatgtt tagaagtaag
     2941 gcagtggact tttacgtatg gaataaattt tttaaaaggg aattattcaa tcatatagtt
     3001 tttccagaaa ataaattata tgaggatatg gttcctatgt atgaagcttt tagggcggct
     3061 agtaaaattg atattttgcc attttcaggt attttttatt atcaaaataa cgatagcatc
     3121 gtttatcagt cttttaattc aaaacagtat gataatattt tgcagagaaa aatattagtt
     3181 gatgaagtaa agaaagatta tcctcgactt attaatttgg ccaatgctcg gttagtagac
     3241 ggatatcttt caacagggtt taaaattact ggcaaaaatc aaaatcagaa aga
//
LOCUS       DACDLM010000148         3282 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.154, whole genome shotgun sequence.
ACCESSION   DACDLM010000148 DACDLM010000000
VERSION     DACDLM010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.154"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            1..585
                     /locus_tag="IV356_002882"
     CDS             1..585
                     /locus_tag="IV356_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP9016491.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            complement(662..1837)
                     /locus_tag="IV356_002883"
     CDS             complement(662..1837)
                     /locus_tag="IV356_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAP9016492.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            1919..2299
                     /locus_tag="IV356_002884"
     CDS             1919..2299
                     /locus_tag="IV356_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HAP9016493.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            2373..2735
                     /locus_tag="IV356_002885"
     CDS             2373..2735
                     /locus_tag="IV356_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016494.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
BASE COUNT         1114 a          539 c          622 g         1007 t
ORIGIN      
        1 atggcattcc cacaactaga tttaaaaagt gaaaaaggac caaaagctgt tatcaaaaca
       61 aaccgtggtg acattactgt tcaattattc cctgaactag caccgaagac ggttcaaaat
      121 ttcattgaac tttccaaaaa aggttattat gatggcgtga tttttcaccg cgttattcct
      181 gatttcatga tccaaggcgg cgatccaact ggaacaggaa tgggtggcga aagtatttat
      241 ggcgaaagtt ttgaagatga attcagtcgt gaactgttca accttcgcgg agctttatct
      301 atggcaaatt caggtccaaa cacaaacgga agccaattct ttattgtaaa taacacaaat
      361 gtgccagcta atatgcttgg acaactagaa ggtgctggat tcccatcaga aatcattgaa
      421 gcgtataaag gtggcggaac tccttggcta gatttccgac atacagtctt tggacatgta
      481 ctagaaggga tggacacagt agatgaaatc gcaaatgtac aacgtggtcc acaagaccga
      541 cctgtacatg atgtagtgat tgaaacaatt gaaatttcag aatagtttgg tatggtacgg
      601 agtaattatg aaaaaggacg aaacctagta aggtctcgtc cttttatttt gaataaatga
      661 tttaatcgat tgtctctaaa gcatacttga ttcgattaag tccttccagt aaagtttctt
      721 ctggacaagc aatattcaag cgcatatgcc catgaccgga aggaccaaac gtgatgccag
      781 gatttaatac gacttttcct ttccgaacaa gagtgttctc caattcttgg tcgtctgaaa
      841 tataggcggt aaaatctaac cacattaagt aagttccttc agggttcatt attctcactt
      901 tcggaagata ctgttcaaaa aactgattaa ctgtttgaac atttttttct agataaggaa
      961 tcagttggct taaccattct ccacccgtct cataagccgc ttgggttcca atcagtccaa
     1021 aagtgttgat ttcgtgctgt tggttcatca ctaaatgttt ttcaaaatca gctttcatct
     1081 ctggattttt gataaatacc attgaatttt tgattgcagc tagattgaaa gtcttggttg
     1141 cggaagtaaa agcaactagt agatcatcta aattaggatc aatcgttagc atggaagtaa
     1201 atgtatgatc gaataaagtt aaatcttgat ggatctcgtc actaaacaga atcacttgat
     1261 gttttaaaca caattcgctt aactgtttca attcttcttt gctccaaaca cgccctccag
     1321 gattgtgagg attgcataaa atcattgctt ttacattgtt ttcttcgatt tttttctcca
     1381 tgtcagacaa gtccatgatg aaatgattat ttttttctag caaagagctt cgaacgatgt
     1441 gacgttgatt tgtttctata atagaggaaa atggaggata aactgggtca tgaatcaaaa
     1501 tagaatcgcc tggttttgta aaagtttgta ctgctgcagc taaactggtt aacacaccac
     1561 ttgtaaaaac gatattttct ttcgtcaact ccacagcatg gtgttggcgt tcccaatgaa
     1621 tgatagcctg atatagttta tcagacagag tggcataacc aaagattcca tgtttgatgt
     1681 attcactaaa cgctttagct accccaccgg gagacaagaa gtccatatct gctacccaca
     1741 aaggaagtaa gtcatccatt tgatatgtct cagcaattgc gtcccatttt acactttctg
     1801 tatcttttct tgaaatctgt ttatcaaatt cgatcatctt aagacctcca gtcattttcg
     1861 tcgcttcttt ttttgagcta tttacagtat aatgataaat gcgaagagag ggaagtagat
     1921 gacttataaa attggacaaa taattgaagg aaaagtgaca gggatacagc cttatggcgc
     1981 attcgtttct cttgataacg agacgcaagg acttattcat gtttcagaag tacaatccgg
     2041 ttatacgaaa aatatccatt cattgttaaa agtcggacag ccagtaacag ttcagatcat
     2101 cgacattgat gaatattcca aaaaaatcag tttatcttta agaacgttag aaaaaacaaa
     2161 tccagctgtt ccatatcgca gaaaaaggta tttcacgaat aaaaatcgta agatcggatt
     2221 taccactatt gcggagcagt tacctatttg gatagaagaa gcattatctg aactagaacg
     2281 gaaagaaaat aagaaataaa aagtgtattt tttctgaaaa tgtgctagaa tttttatgta
     2341 agccatagaa caagttgatc gaggtggaaa ttttggcaag caaaagagtt gctggtacaa
     2401 ttatgttgca tttggaggat ggtactaaaa aatttttggt ccattcaatt gatgacaagt
     2461 tggaatttgc gttagcggaa ctttctgaag gaaagactgg tttagcgaat atacttaatt
     2521 tcttaaaaga aatagttcat atcgatgtta gcaagattag tttgatggaa ttgacaaata
     2581 cacatattaa agaggaaaat gttccgttgt ttgtctttga aactgaacaa aagaatcaaa
     2641 gagaagaatt aggcgaagga tatatttggg aagaaccagg tcaaatgcgc tctgttcttg
     2701 gaacttacga agtagaggga gtgcctttct tctaaaatac agattaagcg aacaaagaag
     2761 tttgaatttt tttcaaactt ctttttttat tgtttggtcc aaaaaataca atgaaatgtt
     2821 ctgctaaaga tagtttttta gtgcatttta ttttcaaaat atgttgaaaa cggttgtata
     2881 acgaataata ataattgatc gaaaaatcat ttcacaaagt aatgcttaat ttatagttga
     2941 ccaaggaaga aatacatgat aaatttaaca gcgttgattc tgaagtggat gttatatcac
     3001 atttctaaaa aatttaaaaa atagttattg acatgttact aacgacatga taagataact
     3061 gagtcgttaa aaaagaacca cttgcgaagc ttgattctat cgaaaaaaac ttcaaaaaag
     3121 ttcttgacaa ataacaaacg ataagttatg ataaatgagt tgctgaaaga tttcgaaaaa
     3181 cgaaatcgaa aaaaactttt aaaaaagagt tgacaatcgc ttgtctctct gatatgatat
     3241 aaaagttgct acggcagcca aaaacgaatc gggaaacact cc
//
LOCUS       DACDLM010000149         3195 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.156, whole genome shotgun sequence.
ACCESSION   DACDLM010000149 DACDLM010000000
VERSION     DACDLM010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.156"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            89..>3195
                     /locus_tag="IV356_002886"
     CDS             89..>3195
                     /locus_tag="IV356_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HAP9016495.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLVGVGLVLGTT
                     ELVQAQDEISPSTPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEEPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSASAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGKKVADLAIERRKDHENYGVGSITDNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSILDVYNKDFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAGEGTSIESGTTVFAVKDGVSLPE
                     DKLPVLKAKDGYTDAKWPEEATQPITADDTEFVSSATKLDDIIENPGENIPAGYHKVT
                     FTAGEGTSIESGTTVFAVKDGVSLPEDKLPVLKAKDGYTDAKWPEEATQPITADDTEF
                     VSSATKLDDKSDADKYNPEGQKVTTELNKEPDASEGIKNKEDLPKDTKYTWKEKVDVS
                     AAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEGEKVEVGGTVDLTDNV
                     TNLPT"
BASE COUNT         1183 a          498 c          671 g          843 t
ORIGIN      
        1 gtaagattcc tattctgtga ataatacgta tcagatttat cttttattct tactaagaaa
       61 ataactatta agggagttga tttgaataat ggttagcaag aataataaga gagtatttct
      121 agaaaaaaca aagaaacgag tattgaagta cagtatcaaa aaattaagtg ttggggttgc
      181 atctgttttg gttggtgttg gtcttgtctt gggaacaact gaactagttc aagcacaaga
      241 tgaaatttct ccaagcaccc cacttgaaac agcgataagc tccgtacaag taggtgacaa
      301 agtagcttcg gggaatactt ttcaggagaa tcctggttat acgaaaaatt ataacttttc
      361 ggatttacaa tttagtcctc aagaactaac tggagacaca ctaaaaggca atacaattgg
      421 atttgaagtt tacggaaaac ataatattgc agcatcaact aaaaactggg aaatccgtct
      481 tcaattagat gaacgattag ctaaatatgt agaaaaaatt caggtcgatc caaagaaagg
      541 aattggatct tctagacgga cctttgtaag aattaatgat tcgctgggta gacctacaaa
      601 tatttggaag gtcaattata ttcgtgcaag tgatggatta tttgctgggg ctgaaacaac
      661 tgatacacaa actgctccta atggggtaat tacgtttgaa aagagcttag atgaaatttt
      721 taaagagata ggcatagaca atctcaagac cgatcgttta atgtatcgaa tctacttggt
      781 aagtcatcaa gacgatgata aaattgtacc aggtattgat agtacgggct actttttaac
      841 agattcagat gatttctata atagcttaga tgtatctgaa aataatcctg accagtttaa
      901 acatggatca gtaagtgcaa aatatgagga acctaatact caaacaaaag atggttcagg
      961 atccacaggt gctaatggag ctataatctt agatcataag ttaacgaaaa attataattt
     1021 ctcatattca gcttccgcaa agggcacgcc ttggtatgct aattacaaaa ttgatgaacg
     1081 attagttcca tatgtagcgg gtatacagat gcacatggtt caggctgaca aagtaacata
     1141 tgatgtttct tttgaatcag ggaaaaaagt ggctgattta gcaattgaac ggcgcaaaga
     1201 tcatgaaaat tatggtgtag gttcaattac tgataatgat cttaccaaac ttattgattt
     1261 tgctaatgca agtccacgtc cagtcgttat tcgatatgtt ttacaattga ctaagccatt
     1321 agatgaaatc ttagaagata tgaaagcaac agcacaagtt gaagaaaata aaccatttgg
     1381 tgaagatttc atctttgatt cttggttgtc ggatacgaat aaaaaattaa tccagaacac
     1441 ttatggaaca ggttattatt atttgcaaga tattgatggt gatggaaacc ctgacgataa
     1501 agaagagagc ggagacacga atccatatat cgggaaacct gaattagaag aagtatatga
     1561 tgttgacaca acagttaagg ggaaagtatt catccacgag ttagcgggaa caggtcacaa
     1621 agcccaactt gttgataaag aaggtactgt attagcagaa aaaactatcg ctccaaatga
     1681 aaaagatggg gctccaattt cagatactgt agaatttgaa tttacgggtg tagattcaag
     1741 taaattaatc gcgaaagatg aattaaaaat ccaaatcgtt tctccaggtt ttgataaacc
     1801 agaagaaggt tcaaccgtta ttaaggaatc accaaaagcg gttgataaac aaaccgtggt
     1861 agttggattt aaaccagatg ctaaagaatc aattcggaat aataaaaact tacctgaaga
     1921 tgcagagtat tcatggaaaa cagagcctga tacttctaac gttactgata gtacgaaagg
     1981 tattgtaact gttaagatcg gaaatcgaac tttcgacgtg gatgtagagt ttgctgtaaa
     2041 agcttctcaa gctatggaaa atgatgcaac atacgtacct ataacaacaa ctccagaaac
     2101 gacagttcaa agtggaaaac ctacatttga taaaccagat gttcctttag ctaaagatgc
     2161 cttttcaatt ttagatgtct ataataagga cttcggtaat gcaagtgttg atgcaaatac
     2221 tggtattgtt acattcactc cagctaaagg tgtaggagaa tcggagccga ttactggaac
     2281 aattcctatt aaaattgttt accaagatgg ttctgtaggc acgaccgatt tagcagtaac
     2341 tgtaagtaaa gatatttatg aaaatccagg agaaaacatt cctgcaggct accacaaagt
     2401 gaccttcacc gcaggggaag gaacaagtat tgaaagtgga acaacggtct ttgcagtgaa
     2461 agatggcgta agcttaccag aagataaact tccagtgttg aaagcaaaag atggttatac
     2521 agatgcgaaa tggccagaag aagcaactca accaattaca gcagatgata cagaatttgt
     2581 atcaagtgca acaaaactgg atgatatcat tgaaaatcca ggagaaaaca ttcctgcagg
     2641 ctaccacaaa gtgaccttca ccgcagggga aggaacaagt attgaaagtg gaacaacggt
     2701 ctttgcagtg aaagatggcg taagcttacc agaagataaa cttccagtgt tgaaagcaaa
     2761 agatggttat acagatgcga aatggccaga agaagcaact caaccaatta cagcagatga
     2821 tacagaattt gtatcaagtg caacaaaact ggatgataaa tctgacgctg acaaatataa
     2881 tcctgaaggt caaaaagtga ctacagaatt gaataaggaa ccagacgcat ctgagggaat
     2941 taagaacaaa gaagatttac caaaagatac taagtatact tggaaagaaa aagtagatgt
     3001 tagcgcagct ggaaataaaa aagggactgt tgtagtgaca tatccagatg gatcatctga
     3061 tgaagttgaa gtagatgtta cagtgacaga caatcgttct gacgccgata aatatgagcc
     3121 aacagtagaa ggcgaaaaag tagaagttgg aggcacagta gatctaacag ataatgttac
     3181 taacttgcca acatt
//
LOCUS       DACDLM010000150         2945 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.158, whole genome shotgun sequence.
ACCESSION   DACDLM010000150 DACDLM010000000
VERSION     DACDLM010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2945
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.158"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            6..977
                     /locus_tag="IV356_002887"
     CDS             6..977
                     /locus_tag="IV356_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HAP9016496.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVGHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTARGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            970..1998
                     /gene="vanB"
                     /locus_tag="IV356_002888"
     CDS             970..1998
                     /gene="vanB"
                     /locus_tag="IV356_002888"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HAP9016497.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKSAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQIIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVHADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTMPGFTSYSRYPRMVAAAGITLPALIDS
                     LITLALKR"
     gene            2004..2612
                     /locus_tag="IV356_002889"
     CDS             2004..2612
                     /locus_tag="IV356_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HAP9016498.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
BASE COUNT          780 a          625 c          812 g          728 t
ORIGIN      
        1 aaccaatgag aaaaagtgtg ggcattactg tttttggatg cgaacaggat gaggcaaatg
       61 ctttccgcgc tttatcgccg gattttcata ttatccctac gctgattagc gatgcgatat
      121 cggcagacaa cgcaaaattg gccgctggca atcaatgcgt tagcgtaggc cataagtccg
      181 aggtttccga ggcgacaatt cttgcgctga gaaaggtcgg ggtaaaatac atttctaccc
      241 gcagcatcgg ctgcgatcac attgatacga ctgccgccga gagaatggga atctcggttg
      301 gcacggttgc gtattcgccg gacagcgttg cggattatgc tttgatgctg atgctgatgg
      361 ccatacgggg tgcaaaaccc accatgcacg ccgtggcgca acaagatttc agattggatc
      421 gtatccgggg gaaagaactg ggggatatga ctgtgggagt tattggaacc ggccatatcg
      481 ggcaagcggt cgtcaaaagg ctgcggggat ttggatgcca tgtgctggcc tatgataaca
      541 gccgaaaaat ggatgcagat tatgtccagc ttgatgagct tctaaaaaac agcgatattg
      601 ttacgctcca tgtgccgctt tgtgcggata cccgccatct gatcggtcag aagcaaattg
      661 gagagatgaa gcaaggcgca tttttaatca acaccgcgcg cggagcgctt gtcgataccg
      721 gggcgctggt ggaggcgttg gaaagcggaa agctgggtgg tgcggcactg gatgtgttgg
      781 agggcgagga tcagtttgtt tataccgatt gctcgcagaa agtgcttgac catccctttt
      841 tgtcgcagct tttaaggatg ccgaatgtga tcatcacacc ccatacggcg tactacactg
      901 agcgtgtgct gcaggatact acagaaaaaa caatcaggaa ttgtctcaat tttgaaagga
      961 gtttacagca tgaatagaat aaaagtcgca atcatcttcg gcggttgctc ggaggaacat
     1021 gatgtgtcgg taaaatccgc aatagaaatt gctgcgaaca ttgatacgga aaaattcgat
     1081 ccgcactaca tcggaattac aaaaaacggt gtatggaagc tatgcaagaa gccatgtacg
     1141 gaatgggaag ccgacagtct ccccgccata ctctccccgg ataggaaaac gcatgggctg
     1201 cttgtcatga aagaaagcga atacgaaaca cggcgtattg atgtggcttt cccggttttg
     1261 catggcaaat gcggggagga tggtgcgata caggggctgt ttgtattgtc tggtatcccc
     1321 tatgtgggct gtgatattca aagctccgca gcttgcatgg acaaatcact ggcctacatt
     1381 cttacaaaaa atgcgggcat cgccgttccc gaatttcaaa ttattgataa aggtgacaag
     1441 ccggaggcgg gtgcgcttac ctaccctgtc tttgtgaagc cggcacggtc aggttcgtcc
     1501 tttggcgtaa ccaaagtaaa cggtacggaa gaacttaacg ctgcgataga agcggcagga
     1561 caatatgatg gaaaaatctt aattgagcaa gcgatttcgg gctgtgaggt cgggtgtgcg
     1621 gtcatgggga acgaggatga tttgattgtc ggcgaagtgg atcaaatccg gctgagccac
     1681 ggtatcttcc gcatccatca ggaaaacgag ccggaaaaag gctcagaaaa tgcgatgatt
     1741 acagttcacg cagacattcc ggtcgaggaa cgaaatcggg tgcaggaaac ggcaaagaaa
     1801 gtatatcggg tgcttggatg cagagggctt gcccgtgttg atcttttttt gcaggaggat
     1861 ggcggcatcg ttctaaatga ggtcaatacc atgcccggtt ttacatcgta cagccgctac
     1921 ccacgtatgg tggccgccgc aggaatcacg cttcctgcac tgattgacag cctgattaca
     1981 ttggcgttaa agaggtgata agtatggaaa atggtttttt gtttttagat gaaatgttgc
     2041 atggcgtccg ttgggatgcc aagtacgcca catgggataa cttcacagga aaaccggtgg
     2101 atgggtatga ggtgaatcgc atcatcggca caaaggccgt ggcgtttgct ctgcgcgagg
     2161 cacaaatcca tgcggctgcg cttggctatg gcttgctttt atgggatgga tatcggccaa
     2221 gaactgcggt ggactgcttc ctgcgttggg cagcgcaacc ggaggacaat ctcacaaaag
     2281 aaaaatttta ccccaatata gagcgagccg agttgattac aaagggttat gtggcctcac
     2341 aatccagcca tagccgtgga agcgcaattg atcttacgct ctaccacctg gatacagggg
     2401 aacttgtttc aatgggaagt aacttcgatt ttatggacga acggtcgcat catacagcaa
     2461 aagggatagg ggatgcagag gcacaaaatc gaagatgctt gcgtaaaatc atggaaagca
     2521 gcggatttca gtcttatcgc tttgaatggt ggcactataa gttgattgat gagccatacc
     2581 ccgataccta ttttaatttt gccgtttcat aatgaaagta ttggttttgt atcagatttt
     2641 ggatttgata aaatctatgc tggtcatgga caatctttta ctggaaagtg gttaaagcat
     2701 cttttgtaat acattgcaaa ttatagtatt caatctgccc agcggcagaa aagaaaaaaa
     2761 ccgctgttgg gcagaccttt cccacgccca ttttgtattt tgctggcggc ggttttgaga
     2821 aatcaaggcc gccgttcttt tctggcagca aaaggtgtgg cggcccatag gaggatgccg
     2881 ctatgctgtt ttgctattgc catgctctaa tccacttcca ccactcaaaa aagccttgcc
     2941 cctcc
//
LOCUS       DACDLM010000151         2877 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.159, whole genome shotgun sequence.
ACCESSION   DACDLM010000151 DACDLM010000000
VERSION     DACDLM010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2877
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.159"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..164
                     /locus_tag="IV356_002890"
     CDS             <1..164
                     /locus_tag="IV356_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="aminotransferase DegT"
                     /protein_id="HAP9016499.1"
                     /translation="MHLQPVFKNYDYIGDDVAETLFDLGVCLPSDTKMTDEDLKYVVS
                     TIKRVINDA"
     gene            157..774
                     /locus_tag="IV356_002891"
     CDS             157..774
                     /locus_tag="IV356_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAP9016500.1"
                     /translation="MRKKTFYQLFGKRILDILLSGIALIVLSPIILIVGFLVRIKLGS
                     PIIFKQERPGKSEKIFSMYKFRTMTDERDHNGEYLPDEIRLTKFGKMLRATSLDELPE
                     LWNILKGDMSIVGPRPLLVEYLPLYSEKQRKRHNVRPGLTGLAQVNGRNAISWEEKFD
                     LDVYYVDKISFFNDLIIIIQTCKKVIKKENINTINNNTPEKFKGS"
     gene            901..2070
                     /locus_tag="IV356_002892"
     CDS             901..2070
                     /locus_tag="IV356_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAP9016501.1"
                     /translation="MCRVLNILFQYENIIKKYKEKRVMAKYYNKKILIMANNDDGLYR
                     FRGMLIKNLVDQGNEVIVSLPKGKNISKLIELGCQIIETPIDRRGINPKTDFKLFFNY
                     CNILKKIKPDMVIAYTIKPNIYGGLACRLRKVSYALNITGLGTAFQKKGVLKSLIVFL
                     YRLAAKKSKVIFFENFENMKTFQTLQIAKQSKYKLLNGAGVDVEHFSYLEYPKDEQVH
                     FLFIGRIMKEKGVDELFEAMKNLYSEEKNCVLDVLGYFEEDYGIKIEKYEKEGWLKYH
                     GYQSDIRPFVERAHCFVLPSWHEGMANTNLESAASGRPIITSDIPGCKEAVIESKSGY
                     LCERKNSCSLYNSMNKFLKLSYEQRINMGKMGRNYMIKKFNKKKVVDETIKSLFS"
     gene            2116..>2877
                     /locus_tag="IV356_002893"
     CDS             2116..>2877
                     /locus_tag="IV356_002893"
                     /inference="COORDINATES: protein motif:HMM:NF025025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP9016502.1"
                     /translation="MSNVSNPLVSVIMGAYNSEKTIGRAIDSIIKQTYLHWEMIICDD
                     GSTDGTVKIIRKYVEKDKRIKLVQNKKNSGLAYSLNHCLKYSSGKYVARMDADDISLP
                     ERFAYQVGFFEKNPEYDVVGCNRIVFDENGDSGIRKSKEIPTINDMYKGSPFAHPTIM
                     MKRSVYTILGGYRVNKDTTRSEDLEMWFRFFNEGFRGYNLQRVLFKYQETSEDFHKRS
                     LRAAYGITKVLLRGYKLIGVSKYKYIYAFKPIISAI"
BASE COUNT         1125 a          327 c          535 g          890 t
ORIGIN      
        1 caatgcattt acaacctgtt ttcaaaaatt atgattatat tggcgatgat gtagcagaaa
       61 ctttatttga cttaggagta tgtttaccat cagatacaaa gatgacagat gaagatttaa
      121 aatatgtagt atctacgatt aaaagagtga tcaatgatgc gtaaaaaaac tttctatcag
      181 ctttttggga aaagaatttt agatatccta ttgtcaggaa ttgctctcat cgttttatcg
      241 ccgataatct taattgtagg ttttttagta agaattaaac ttggttctcc aattatcttc
      301 aaacaagaac gaccaggaaa aagtgaaaaa attttttcca tgtataaatt tcgtacaatg
      361 actgacgaaa gagaccacaa tggagaatat ttacctgatg aaattcgact aactaaattt
      421 gggaaaatgc ttagagcaac aagtctggat gagctacccg aactttggaa tattttgaaa
      481 ggtgatatgt ctatcgtagg acctcgtcca ttattagtgg agtatttgcc actatatagt
      541 gagaagcaac ggaaaagaca caacgtaaga ccaggattaa ctggactggc tcaggtcaat
      601 ggaagaaatg ctattagttg ggaagaaaag tttgatttag atgtttatta tgttgataaa
      661 attagtttct ttaatgatct tattattata attcagacat gtaaaaaagt aatcaagaaa
      721 gagaatatta atacaatcaa taacaatacc ccagaaaaat ttaaagggag ttaaatacag
      781 cagcttaatg caagttttgt gacttgcatt atatttaggt ataaatcaaa gcgagtatat
      841 tagaattata taacatatgt taaaaaaacg catagctaat aaaagtatga ttttaaaaat
      901 ttgtgtagag ttttaaatat actgtttcaa tacgagaaca ttataaaaaa gtataaggaa
      961 aagagagtta tggcaaagta ttataataaa aaaattctta taatggcaaa caacgatgat
     1021 ggtctttacc gttttcgagg aatgctcata aaaaacttag tagatcaagg taatgaagtt
     1081 attgtatctc ttccaaaggg caagaatatt tctaaattaa ttgaacttgg atgtcaaatt
     1141 attgaaactc caatagatag aagaggaatt aatccaaaaa ctgactttaa actatttttt
     1201 aactattgta atattttgaa aaaaataaag ccagatatgg tcattgctta tactatcaaa
     1261 ccaaatatat acggtggatt ggcatgtcgg ttaagaaagg tttcttatgc attaaatata
     1321 accggattag gaacggcatt tcaaaaaaag ggggttttga aaagtcttat tgtatttttg
     1381 tatagattag cagctaaaaa atctaaggtc atatttttcg aaaattttga aaatatgaaa
     1441 acatttcaga ctttacaaat tgctaaacaa agcaaataca agctattaaa cggtgcagga
     1501 gtagatgtag aacactttag ttatttagaa tatcctaaag atgagcaagt tcatttttta
     1561 tttattggaa gaattatgaa agagaaaggt gtagatgaac tttttgaagc aatgaaaaac
     1621 ttatatagtg aagagaaaaa ttgtgtactt gatgtccttg ggtattttga agaagattac
     1681 ggcataaaaa ttgaaaaata cgaaaaagag ggatggttaa aatatcatgg atatcaatct
     1741 gatattcgtc cctttgtaga aagagcacat tgctttgttt tgcctagttg gcacgaagga
     1801 atggcaaata ctaaccttga atcagcagca tcagggagac caattattac aagtgatatc
     1861 ccagggtgta aagaagcagt tattgaatcg aagtctggtt atttatgtga aagaaaaaat
     1921 agttgtagtc tctataattc gatgaataaa tttctaaaat tatcatatga gcagcgcatt
     1981 aacatgggaa aaatggggag aaattatatg attaaaaaat ttaataagaa gaaagttgtc
     2041 gatgaaacaa ttaaatcatt atttagttaa aaagatatgt tttgcaaagt atgtgataga
     2101 aaagagggat tctgtttgag taacgtaagt aatccattag taagtgtaat catgggagcc
     2161 tacaattcag agaaaacaat tggaagagca attgattcaa ttataaaaca aacatattta
     2221 cattgggaaa tgataatttg cgatgatgga tcaactgatg gaactgtaaa aataatacgg
     2281 aaatatgtag aaaaggataa acgtattaag cttgttcaaa ataaaaaaaa tagtggatta
     2341 gcatattcat taaatcattg tttgaaatat tcatcgggaa aatatgttgc aaggatggat
     2401 gcagatgata ttagtttacc agaaagattt gcataccaag ttggattctt tgaaaaaaat
     2461 ccagaatatg acgttgtagg atgtaatcga atagtattcg atgaaaatgg tgattctgga
     2521 atacgaaaat caaaggaaat tccaactatt aatgacatgt ataaaggttc tccatttgct
     2581 catccgacaa taatgatgaa acgaagtgtt tatactattc taggtggtta cagggttaac
     2641 aaagatacaa caagatcaga agatttagaa atgtggtttc gattcttcaa tgaaggattt
     2701 agaggttata atttacaacg agtcttattt aaatatcaag aaacaagcga agattttcat
     2761 aaaagaagtt taagagcagc ttacggaata acaaaagtat tgttgagagg ttataagtta
     2821 ataggagtta gtaaatataa atatatttac gcatttaagc cgattatttc cgcaata
//
LOCUS       DACDLM010000152         2857 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.160, whole genome shotgun sequence.
ACCESSION   DACDLM010000152 DACDLM010000000
VERSION     DACDLM010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2857
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.160"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            562..843
                     /locus_tag="IV356_002894"
     CDS             562..843
                     /locus_tag="IV356_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016503.1"
                     /translation="MDILVRKIDSKVIAKIDKRCQELTNKTGKKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLEKFIAIQTKNTQVLNDYVHTNNQLIETLIGGK"
     gene            845..1261
                     /locus_tag="IV356_002895"
     CDS             845..1261
                     /locus_tag="IV356_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016504.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIERNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMSEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKT
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(1422..1688)
                     /locus_tag="IV356_002896"
     CDS             complement(1422..1688)
                     /locus_tag="IV356_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016505.1"
                     /translation="MAFRFRCDRGGRKMTEKFPYEYYQNLEKLESAIQLVKLDLLDEN
                     LLKYKNITPERKGKLKKMQQLFDEEDGISDVIFDTWSEFHGEYN"
     gene            complement(1646..2620)
                     /locus_tag="IV356_002897"
     CDS             complement(1646..2620)
                     /locus_tag="IV356_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HAP9016506.1"
                     /translation="MGKKRTIVNEWEKLTAPSNRRLNVGESVKMIKMDWSIDRITIVG
                     TLNENIYYHTQNDVLILDFEQLMRVNEGNGHLKAVGNNGWQLVDQHEENIAYIEILKW
                     QEGKGRIDFNPNKISQFLASSMKKFIHDLFLEPHFSRADVACDLIDVPDEFITQYRVV
                     DPVSFKPIYGRSGKLETAYWGSRASERQIRMYNKKLEQEAKRKIVPKEVETWWRLELQ
                     LRRGKATDWYEMVQESLDSFASPHYFPEDVKTLDRVMIKGLLYDHSEWSTISRDLKYR
                     LRKLLKQESQNDELTNHLRETFEESADELKRELDTWLLGLDVTEEEEK"
BASE COUNT          926 a          624 c          397 g          910 t
ORIGIN      
        1 aaaaaaataa aaagacctca gggaatttca ttccccgaac cccttgagcc tcctcctgcc
       61 gaaatcattt cacgcttccg ctcttcattt cattcagttc tcggctttca caatctaaca
      121 cgccgtttcg ctaccagtcg ccttacaggc tccattctcg cttctcttac gtgttttacc
      181 gattgtgccg acaactaaac gaaatgaacg ctaaaacgtc ttagaacgca aaatacacgc
      241 ttataaaatc atttcatctt gattatatgc tcatcataat cgttcaattt gacatcattt
      301 ccgtaaactt tttttatttt tataagcaga aaaaagtcgc acatcaacat ttttttaaag
      361 agcataagga aacgtgtacc cactttctaa aaaaagcggg cagataggct gtgcctatca
      421 cgtttctaag aaaaaaattt gatatcactt tttcgccatt gtgactagct tatgtatagt
      481 gtttcagcaa aaaacagcta tacaaatact atattcgtat gatatacata aattatacac
      541 aaatgcgaaa ggagtttttc tatggacatt ttagttcgga agattgattc aaaggttatt
      601 gcaaaaatag acaaacgttg ccaagaactc acaaataaaa ctggcaaaaa atggagtcga
      661 aataaatatc taaaagtttt aatcgaaagt gattttgacc gtcaacttac gacttacaaa
      721 aaagaccaat tcgatttatt actcgaaaaa tttatcgcta ttcagacaaa aaacactcaa
      781 gtactaaacg actatgttca tacaaataat caacttattg aaacacttat tggaggaaaa
      841 tagcatgaga aaaacttctg ttcaaaaaca cgttaccctt tatcccagtc acgtggacgt
      901 tttagattcc attatcgaaa gaaatccaga tatcaacaat tactcggaag ccattcgttt
      961 tttatgtatg agttatgaac ctgataccaa cacgactact accagcaatc aagccaaact
     1021 aaatgctatg ggaaaagaaa tttccatcat gtccgaaatc attgcagaat ttgctgattt
     1081 atatctaaaa gatacaggcg ttcttattgg cacaaattct aaagtgtatc aagaagtgaa
     1141 agaaaaaacc gaagctaaac taaatccgtc gaatcgaaat cgaccaaaga atcatcaaaa
     1201 agaaacgagt caaacagtca cttctagaaa tttcgaccca acaaattttc taaaacgcta
     1261 aaaaataaaa cgagaatttt tttatttctc gttttatttt ttaggaaagc cggtcttaca
     1321 gcaagatttg caagttaccg gtaacttgcg gaaaagaaga agccgctcac gcgacttctt
     1381 ctttttgcat tttctgaaag ctaccacaat tcctaacttc gctaattata ttctccatga
     1441 aattcgctcc atgtatcaaa aatcacatct gaaattccat cttcttcatc aaataattgc
     1501 tgcatttttt tcaatttacc ctttctctct ggcgtaatat ttttgtattt tagtaaattc
     1561 tcatccaaca aatccagctt gaccaactga atagcactct ccaatttttc tagattttga
     1621 taatactcgt atggaaattt ctcagtcatt tttcttcctc ctctgtcaca tctaaaccta
     1681 aaagccatgt atccaattct ctttttaatt cgtctgcaga ctcctcaaat gtttctcgta
     1741 aatgattcgt caattcatca ttttgacttt cttgcttcag caatttcctt agccgatatt
     1801 tcaagtcacg actaatagtt gaccactcag aatggtcata caacaacccc tttatcatca
     1861 ctctatccaa cgtttttaca tcttcaggaa aataatgcgg actagcaaaa ctatccaaac
     1921 tttcttgaac catctcatac caatcagtcg cttttccacg gcgcaattgt aactccaaac
     1981 gccaccacgt ctcgacttct ttaggtacaa tttttcgctt tgcttcctgt tccaacttct
     2041 tgttgtacat ccgaatttgg cgttcgctgg cacgactacc ccaataagcc gtttctagct
     2101 taccagagcg tccataaatt ggtttgaagg acacagggtc aactacacga tattgtgtaa
     2161 taaactcatc aggcacatca ataagatcgc aggcaacatc cgctcgtgaa aaatggggct
     2221 ctaaaaataa atcatgaata aattttttca tagagcttgc taaaaattga ctaattttat
     2281 tggggttaaa gtcaatccgc cctttaccct cttgccattt caaaatttcg atataggcaa
     2341 tattttcttc gtgttgatct accaattgcc aaccattatt cccaacagct tttaaatgac
     2401 cattaccttc gttcactcgc attaattgct caaaatctaa aatcaacaca tcattttgag
     2461 tgtgataata aatattttca ttcaaagttc cgacaatcgt aattcggtca atcgaccaat
     2521 ccatttttat catttttacg ctctcaccga catttaaccg cctgttagag ggggctgtta
     2581 atttttccca ctcattcaca attgttcttt ttttacccaa attttgttcc tcctcaaaga
     2641 aaaaaagaga tttttggaaa gaatttccag agttcacgta actctaaaaa tccacatcca
     2701 aaaatctcta gcttgaagaa acctaaaaat attcgtataa tgaacttgag ttacggaact
     2761 aggctagtag tttccgtaaa ggtcgagagt gttagcgcac tgctcgacta tttttttgct
     2821 cttttttctc gttttctttg attatagcac tcctctt
//
LOCUS       DACDLM010000153         2786 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.161, whole genome shotgun sequence.
ACCESSION   DACDLM010000153 DACDLM010000000
VERSION     DACDLM010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2786
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.161"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            54..656
                     /locus_tag="IV356_002898"
     CDS             54..656
                     /locus_tag="IV356_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016507.1"
                     /translation="MLKLISYAKKANSLSLVDNLDNLLPDKLIYDENEDNSQKQIIIF
                     ELYLKWLSSLSVSPESNDDDKYFANKLFQFIFPDYSSMPFFTLINFMLYVKEHLGYDD
                     LVEMIKAYDKEPYPFKGINTGSDMAMISGETVEEILANYKEQNIKTLELIKKNIKYYD
                     PLLANKENIDKLLNAIADSDVRSPRIDELKEEILMYKELF"
     gene            complement(653..1276)
                     /locus_tag="IV356_002899"
     CDS             complement(653..1276)
                     /locus_tag="IV356_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP9016508.1"
                     /translation="MKIAYIRVSSIDQNEQRQIEEMKKFGAEKIFIEKQSGATITHRP
                     IFQEALEFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PHLDKFIKDLIIQILAMIAEQERTESKRRQAQVIKIAKANGVYKGRPKLYSADTKNPQ
                     RRLVYENIVKDLNEGIAISKIAKNYNITRQTIYRIKNDIEYNSNQMN"
     gene            1594..1932
                     /locus_tag="IV356_002900"
     CDS             1594..1932
                     /locus_tag="IV356_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP9016509.1"
                     /translation="MNGIEDENLRRLINSLVIELYKYQAESERKKIKERQAQGIEIAK
                     KKGKFKGRQLKFKKNDPRLKHAFDLFLNGLSDKEVEEQTGINRRTFRRYRARYNVTVD
                     QRKNNEKRDS"
     gene            2024..2765
                     /locus_tag="IV356_002901"
                     /pseudo
     CDS             2024..2765
                     /locus_tag="IV356_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320596.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1005 a          427 c          483 g          871 t
ORIGIN      
        1 aatttttaga agaattatct ggagaagaat atagattatt cctaaataat aatattttaa
       61 aattaatatc ttatgccaag aaagctaata gcctatcttt agtagataac ttagataatc
      121 ttttacccga taaacttatt tatgatgaga atgaagataa ttcacaaaaa caaataatta
      181 tatttgaatt gtatttaaag tggcttagca gcctgtcagt gtcaccagaa agcaatgatg
      241 atgataaata ttttgcgaac aaactgtttc aatttatatt tccagactat tcttcaatgc
      301 cattttttac attaataaat tttatgctgt atgttaaaga acacttagga tatgatgatt
      361 tagtagaaat gataaaggca tatgataaag aaccttatcc attcaaagga atcaatactg
      421 gttcagatat ggctatgatt tcaggcgaaa ctgtagaaga aattctagct aattacaaag
      481 aacaaaatat aaaaactctg gaattaatta aaaagaatat aaaatactat gatcctttac
      541 tagcgaataa agaaaatatt gataagttat taaatgcaat tgctgattct gatgttagat
      601 ctcctagaat tgatgagtta aaagaagaaa ttttaatgta taaagaactt ttttaattca
      661 tttgattact gttatactca atatcattct taattctgta aatagtttgt ctagtaatat
      721 tgtagttttt agcaattttt gaaatagcta tgccctcatt taaatcctta acgatgtttt
      781 cataaactaa acgtcgttga ggattttttg tatctgcact atagagtttt ggacgacctt
      841 tatagacgcc atttgctttt gcaattttaa tgacttgcgc ctggcgtcgt ttagattcgg
      901 tacgctcttg ctctgcaatc atggccaaaa tttggatgat taaatcttta atgaatttat
      961 ccaaatgagg attgccaatt gcttcagcca tgatcggtag actggtgatg atcagctgca
     1021 cgtttttctt ctttaggtaa ttgactgaag caatgatttc gtcgtaattt cttccaagtc
     1081 ggtcgattgc ttcgacaata aaaatatctt ggtctcggac aaactctaaa gcttcctgga
     1141 aaatcggtcg atgagtaatc gttgctccag attgtttctc gatgaaaatt ttttctgcgc
     1201 cgaacttttt catttcttca atttggcgtt gctcattttg atcaatcgac gaaactcgaa
     1261 tataagcaat tttcaaaatt tttacctact tcctcaaact atttaaaata cactcaaaat
     1321 caacactaat ttttttatac actataaagc tgtcattttt ctagataaat ggcataaatt
     1381 ttcagcgcta agtgacaaaa gcaactaatt tttcatgata gatttttaaa tatctcaatc
     1441 tatctccaaa attagttgct tttgtagcta tagttgacta tgaatatgac aaataattag
     1501 aaaaaactgt gccaattaaa tatcaaaatg acaaattgat gaatcaaatt caaattaagg
     1561 ggggcaaccc tggaagtctt aaatttaccc tcaatgaatg gtattgaaga tgaaaattta
     1621 aggcgtttga ttaatagcct tgtcattgaa ttgtacaagt atcaagcaga atcagaacga
     1681 aaaaaaatta aggaacgtca ggcacaagga atcgaaattg ctaagaaaaa aggcaaattc
     1741 aaaggtcggc aactgaaatt taaaaaaaat gatccacgtt taaagcatgc tttcgatttg
     1801 tttttgaatg gtttatccga taaagaagtt gaagaacaaa ctgggatcaa tcgccgaacg
     1861 tttagaaggt atcgagcaag atataacgtg acagtagatc aaagaaaaaa caatgaaaag
     1921 agggatagtt aatgagtacg gttattttag ctgaaaaaca agccaggcat tagcctacgc
     1981 aagtgcttta aaacaaagca ccaaaaaaga cggttatttt gagatcaaag acccactatt
     2041 tacagatgaa acgtttatca cctttgattt tgggcattta gtggaattag cagaaccagg
     2101 tcattatgac gaaaagtggc aaaattggaa acttgaatct ttgccgattt ttcctgatcg
     2161 atacgatttt gaagttgcaa aagataaggg aaagcagttt aaaattgttg cagaacttct
     2221 caaaaaggca aatacaatta ttgttgcaac agatagcgac agagaaggtg aaaatatcgc
     2281 ctggtcgatt atccataaag caaatgcctt ttcaaaagat aaaacattta aaagactatg
     2341 gatcaatagc ttagaaaaag atgtgatccg aagcggtttt caaaatttgc aaccaggaat
     2401 gaattactat cccttttatc aagaagcgca aacacgccaa attgccgatt ggttgatcgg
     2461 catgaacgca agccctttgt atacgttaaa tttacaacag aagggcgtac aaggtacatt
     2521 ttcactagga cgtgttcaaa cgcccacctt ataccttatt tttcagcgcc aggaagctag
     2581 tataaaagta aaacaagggt catttaaggg cgttctaagc cccacacagc gttttaaaac
     2641 ccaagaggag cttttttgct tttgtttctt ctaaacaagc taaaataggc aatcaagagg
     2701 ggataattgc tgatgttcaa accaaagaga tggataggct acaattaact agacagaaaa
     2761 attaaggtgt gtagactaga agaaaa
//
LOCUS       DACDLM010000154         2738 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.162, whole genome shotgun sequence.
ACCESSION   DACDLM010000154 DACDLM010000000
VERSION     DACDLM010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.162"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..234
                     /locus_tag="IV356_002902"
     CDS             <1..234
                     /locus_tag="IV356_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9016510.1"
                     /translation="SLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            244..900
                     /locus_tag="IV356_002903"
     CDS             244..900
                     /locus_tag="IV356_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP9016511.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            900..2276
                     /locus_tag="IV356_002904"
     CDS             900..2276
                     /locus_tag="IV356_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9016512.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            2406..>2738
                     /locus_tag="IV356_002905"
     CDS             2406..>2738
                     /locus_tag="IV356_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP9016513.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDI"
BASE COUNT         1079 a          323 c          484 g          852 t
ORIGIN      
        1 tccttatttt taggaaatgt attactaaaa gtaattgtag atggattcat taactcagag
       61 gattcaatga tttccggtgg aagtttaata aataatagta gttttatgtc aaatataaca
      121 acacttggac aaagttattt aatattaata agtattattg ttttatcagt tgtatttgct
      181 tcttcattaa tgttaatcaa gaagcctaaa gaaatcttat caaaaataag ttaggagaaa
      241 ataatggata tattagaaat aaagaatgta gcatatagtt atgcaaattc taaagaaaaa
      301 gttttgtcag gagtaaatca aaaatttgaa cttgggaagt tttatgcgat agtaggaaag
      361 tcaggaacag gaaaatctac acttctttcc ttacttgctg gacttgataa acctcaaaca
      421 ggaaaaatat tgtttaagaa tgaagatata caaaataaag gatatagtaa tcatagaaaa
      481 aataatatat ctttagtatt tcaaaactat aatttaatag attatttatc accaattgaa
      541 aatattagat tagtaaataa atcagcagat gaaagtatct tgtttgaact aggtttagat
      601 aaaaaacaaa taaaaagaaa tgttatgaaa ttatctggtg gacagcaaca aagagtagct
      661 attgctagag cattggtatc agatgctcca ataatactag ctgatgagcc tactggtaat
      721 ctagacagtg ttactgctgg agaaataatt aatatattaa agacattagc taaagataga
      781 aataaatgtg taatagttgt aacacatagt aaggaagtag cagattctgc ggatatcatt
      841 ttagaactaa gtggtaaaaa gttgaaaaaa gtaaataaaa tgaatttgga ggttgaataa
      901 tgataaaaaa tgcatttgct tatgtaacta gaaaaagttt aaaatcatta attatcatat
      961 tagttatttt atctatgtca actttaagtc tcattagttt atctattaaa gatgctacgg
     1021 acagagcttc aaaagaaaca tttgctaata taacaaatag tttttctatg gagataaata
     1081 gacaagtaaa tccaggaaca cctagaggtg ggggaaatgt aaaaggtgaa gatattaaaa
     1141 agatatctca aacagatagt atagactcct atgtaaaaag aataaacagt gttgcagatt
     1201 tagttgatta tgatattatt gaaactcaag agactcttgc gaatcaatca cctgaaagag
     1261 caaagaattt taaaagaaca gttatgttaa ctggggttaa cgactcaaca aaagaaacaa
     1321 aatttgtatc agaagcatat aaattagtag aaggaaagca tttagaaaat gaagataaaa
     1381 ataaaatctt aatgcataaa gatttagctg aaaaaaataa ccttaaagtt ggagataaga
     1441 taaaaataaa atctaattta tttgatgctg ataatgagaa aggtgcagat gaaacagtag
     1501 aagtagaaat taaaggtcta ttcgatgggc ataatagcgg tgtagtaagt gcagcacaag
     1561 aactatacga aaatacatta atcactgata ttcatacagc tgctaaagtt tatggtaata
     1621 ccgaagatac agctgtatac caagatgcaa cattctttgt aaaaggtgat aagaatcttg
     1681 atagtgtaat aaaagatctt gggaaattag atataaattg gagagaatat aatttgatta
     1741 aaagttcatc aaattaccct gcattacaac aatctatatc aggtatttac tcaatttcaa
     1801 ataaattatt ttttggctca ttaatatttg caggagttgt agtttcatta ttattattct
     1861 tatggatgaa tgctagaaag aaagaaatag cagtattact atcattaggt atatcaaaat
     1921 tagaaatttt tggtcaattc ctaattgaga tggtatttat atcaatcccc gcattcgttg
     1981 gttcctattt cttagctcaa tatacagctg acaagcttgg gaataatata ttgaataagg
     2041 ttactggtga tatagctaaa caaatagcta aacaatctgc atctagccaa ttaggtggtg
     2101 gggcagaagc tgaaggattt aacaagacat tatcaagttt agatatcaat gtattaccta
     2161 aattcatgat ttatgtagtt atatttatga gtttagtact tcttgtatca ttgattattt
     2221 cttcattcaa tatattaaga aggaatccaa aagaattatt aattgacaat aattaaaatt
     2281 ttcggtgctt tttagcacca aaaatgagag tgtaatataa accgtgtaag taaccatcaa
     2341 tcctaggcgg gtggttgctt cacggttttt atttttctaa aataagatca agaggtgatt
     2401 acacgatggc tagaaagaaa agaaatcctg atgctgagaa gttagctgaa tccattttga
     2461 atacttatca acccgaatct gtagaggata tgcaagatgt tttaaaagat gtgtttggtc
     2521 ccttatttga aaaaatgctt caaggagaat tgaataacca tttagggtat gacgcccatt
     2581 ctaaagagcc aaagaaacat gacaatcgac gaaacggtta tggcaataag acgcttaaaa
     2641 cgagctttgg taaagtaaac attgatgttc ccagagaccg ggaggcttct tttgaacctg
     2701 agttgattcc taatagaaaa cgagatgtct ccgacatc
//
LOCUS       DACDLM010000155         2731 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.163, whole genome shotgun sequence.
ACCESSION   DACDLM010000155 DACDLM010000000
VERSION     DACDLM010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2731
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.163"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..334
                     /locus_tag="IV356_002906"
     CDS             <1..334
                     /locus_tag="IV356_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HAP9016514.1"
                     /translation="KLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKK
                     TGGLRYAPALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKRED
                     FNEAQKIR"
     gene            350..1111
                     /locus_tag="IV356_002907"
     CDS             350..1111
                     /locus_tag="IV356_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAP9016515.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            1242..2576
                     /locus_tag="IV356_002908"
     CDS             1242..2576
                     /locus_tag="IV356_002908"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HAP9016516.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
BASE COUNT          926 a          463 c          585 g          757 t
ORIGIN      
        1 gaagctattt gaagagtcag acgaagagac gattgcagga atcatcaaac atgaactttg
       61 ccattatcat cttcatctag ctggaagagg gtatcagcat aaagatatgg atttcaagta
      121 tcttttgaaa aaaacaggag ggttgcgcta tgcaccagcc ttgacgaaga aacagataaa
      181 gatggagtat tatcgatgcc aagattgttc tgccacgatc tgccgcaaga gaagaatcga
      241 tgtacgcaaa tatcgttgtg gaagatgtca tggagaaatc aaatggattg agacaaaaag
      301 agaagacttt aatgaagcac aaaaaatcag atgaaaggat agaaggcctt tggaaaaaag
      361 tgagcagagg aatctaaaag actggaatca gctattaaat tttttagccg cacctgaaga
      421 gggaaatttt gaggaactga cggcacctac acttatttta gctggaaact gtcttcctat
      481 cttagctgat aaagcagcac aaatgtattt aaatggccaa gtagatcaat tgtttttggt
      541 cggaggggtg gggcatgcga ctagaatcct ttatgagaat tttgaaaagc aaggatttca
      601 ttttgaagat ggcatgagtg aaagtgaaat ctgtcgtcag tatctaaaag aagtctatga
      661 tttgcccgat aaggcttttc tgatagaatc gaagtctaca aattctggag agaacgccac
      721 tttttcactg gagattcttc attccttagg agctgtacca gaaaaaatct tattgatgaa
      781 tgatccgaca ctgcaacgca ggactcgagc aacttttgag aaagtatggc aaaatgaaca
      841 aactattttc gcgaatgctg tgccatttgt gccggaaatc cttcactttt ctgaagagat
      901 catctttaca gcaaaagaac tgaatcatca atggcctaag gaatatttcc atgcgctagt
      961 attaggagaa atggaacgtc tccatgacga tgagaacggc tatggtccga aaggaaaaga
     1021 ttttattcct cacattgata tatcagagga agtttggtct tcttacacca gaattaaaga
     1081 gtcaataaaa acggattttt ctcgtacttg accattttag caagcgaatc ctcctttcca
     1141 aataaatttg gttgaaattt tcaatcgttt ataagataat gaggagcgtg ttgaatgtaa
     1201 tagctaaaag aatggacgct agataagaga agaggattca aatggaaaat caaaataaat
     1261 tgtatcattt tgttggtatc aaaggttcag gaatgagctc cttggctctt gttttacatg
     1321 aacaaggtct aaatgtccaa ggatcagaca ttgaaaaata tttctttaca caaagagatt
     1381 tagaaaaagc aaatatcacg attctgccat ttaacgcaga taatgtaaaa ccagggatga
     1441 cgatcattgc aggaaatgca tttcctgatt cacatgaaga aatccagcga gcaaaagaat
     1501 taggtttgga agtgattcgc tatcacgact ttattggtca ttttatccaa aattatacga
     1561 gtatcgctgt aacaggctct cacggaaaaa caagtacgac tggactgctc tctcatgtat
     1621 tgagtggtgt ccgtccaaca agttatctaa ttggagatgg aacaggacat ggtgatccgc
     1681 aagcggaatt cttttcattt gaggcctgtg aatatcgccg tcatttcctt gcctattcac
     1741 cagactatgc aatcatgacc aatatcgatt ttgatcatcc ggattattat acaagtatcg
     1801 acgatgtatt tacagctttc caaacaatgg ctggacaagt gaaaaaagct atttttgcgt
     1861 atggtgacga tgcttattta cgcaaattaa aagcaaatgt gccgatttat tattatggtg
     1921 tcacagaaaa cgatgatatc caagcacgaa acatcgaacg cacaacttct ggttctgctt
     1981 ttgatgtcta tcatggggat gaatttgttg ggcacttcac tgtaccagca ttcggtaaac
     2041 acaatatctt aaatgcttta ggtgttattg cagtagctta tttcgaaaaa ctggatctga
     2101 aagaagttgc agaagaaatg ctgactttcc caggagtaaa acgtcgattc agtgaaaaga
     2161 tcgtagcaga catgaccgta gtcgatgatt atgcgcatca ccctgcagag atcaaagcaa
     2221 cgattgatgg cgcacgccaa aaatatccag ataaagaaat aattgcagtt ttccaacccc
     2281 atacgtttac gcgtacgatt gcattgatgg atgaatttgc agaagcactt gatttagctg
     2341 ataaagttta cttatgcgat atttttggtt cggctcggga agaacaagga aacgttaaga
     2401 ttgaagacct tggagcgaaa atcaaaaaag gtggagaagt catcaaagaa aataatgtat
     2461 ctccattgtt agattatcat gatgcagtag taatcttcat gggtgctgga gatgttcaaa
     2521 aatttgaaca agcgtatgaa aaacttttaa gcagcacgac gaaaaatgta ctgtaataca
     2581 attactgcag tgtccttata aaaatagaaa gagggggagt ggcaaaaatc ttgccaagcc
     2641 cccttttttg caacttatga taaacggtgt tcaaaagctt gcatctgcgg taataagccc
     2701 aatcaaatca aaaacatgag aagctgtttt t
//
LOCUS       DACDLM010000156         2705 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.164, whole genome shotgun sequence.
ACCESSION   DACDLM010000156 DACDLM010000000
VERSION     DACDLM010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2705
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.164"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            718..2595
                     /gene="ltrA"
                     /locus_tag="IV356_002909"
     CDS             718..2595
                     /gene="ltrA"
                     /locus_tag="IV356_002909"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAP9016517.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
BASE COUNT         1039 a          417 c          599 g          650 t
ORIGIN      
        1 gtgaaaagct gtgggttgca agtagtctaa aaactattgt aataactctt ataacgagaa
       61 gtcaaatgag tgggtaacgc cacaaagggc ttccactgat actccgacat gcaacaagta
      121 gtttatgcag accaacgttg tgtgaagctc ggtgaagtcg gctgaaggat accgtaaggt
      181 aaaagaaata gtgaatacca cgaaagttct ctagaggtaa agggtgtatc cgataagtcg
      241 ggtgtccaaa aaaacttaat atggtgagta tgtacaaacg tactgacgaa ctagcgaatg
      301 tactgtccga aaggcatagc tcctagaaat gggagagaca gtgagcaaaa aatcactcat
      361 tgtgctaact tgtggttgag taaaagtcgt tgttatgaaa gaccatgctg cgttacaggc
      421 gtaggagaag ttagggggca aaagctagca tctaagttaa ggcatgtgga tagatataag
      481 ggaacagggg aagccatcaa catggagagt gcatactcga tgaagtggta gtaagaaata
      541 tgtgaatgac aaataactta ctttagtgat ggtgaaagta gagtcacgac tgatgaaggt
      601 tctgtaatgg aactggagga acaggctcga ttcgtctgta aaagtcatga aacccgttca
      661 accatgggat tctcgtatga ctaaaaaggt cacgagccaa ttggagcgtg ataaaccatg
      721 acaaaagaaa caagtccaaa agataggaag ttgcggcatg cagaatatta tggcatgacg
      781 gaaatcttcg ataagatata ctccaaaagt ttgaagggag ataatttcaa gaatctaatg
      841 cagattatca tttctgataa caacattgtc ctagcatatc gtaatatcaa gagaaatcac
      901 ggtagtgtga caagaggaga agatggagta acgattaaag atattgaaaa tctcaaccgt
      961 aatgaattcg tagaaattgt taggaagcga ttcgcacatt ataaccctcg gaaagtaagg
     1021 cgtgtagaaa ttcctaaata taatggtaaa ttaagaccgt tgggtattcc atcaatatgg
     1081 gatagaatcg cgcagcaatg catcttacaa gtattagaac caatatgtga agcaaaattc
     1141 aataatcaca gctatggttt ccgcccaaat agatcagcag aacacgcaat agcagattgt
     1201 atggcccgaa tgaatcaaag tcacatggaa tatgtggtag atgtagatat caaaggtttc
     1261 ttcgacgaag tcaatcatac taaactcatg agacaaatct ggtctatggg tatacgagac
     1321 aaacagcttc tcttaatcat taggaaaatg ttaagagcac ccgtagtact tccaaatggg
     1381 aagttgatat acccaacaaa aggaacacca caaggcggaa tacttagccc attacttgcg
     1441 aacatcaatc tcaacgaatt tgactggtgg atagcaaatc agtgggagga aaaagatgcc
     1501 aaagagctaa aacatcattt taggaaaaat ggagcttggg ataaaggtaa tatctatcac
     1561 aagctcagaa agagtacaac tctaaaagaa atatacctag tgagatacgc agatgatttt
     1621 aaaattttct gtagaaatta taatgaagcg aaaaaagttt tctatgcaac taaaatgtgg
     1681 ttacaggagc gtctaaagtt accaatatct gaagaaaagt caaaaatcac aaatctttca
     1741 aaagaagaaa gtgaattttt aggctttacg atgaaattag tgaccaaagg taacaaaaag
     1801 gttgttaata cgcatatagg tacaaaagca caaagcatga ttaaagtgaa actaaaaaaa
     1861 caaatcaaac gaattcaaaa aagtcctaat agcaaagata cctttatcta tattggagtc
     1921 tataacagta tggttattgg gattcataat tacttcaaaa ttgcgactca ttgtagtgta
     1981 gcaatgcgaa aaattgcaag agaactcaga ccaagttttg aaatacgact acgagaacaa
     2041 ggaatctcaa aagaaggaca atacggaaag tacgaaggat acaagcctta cctacggtca
     2101 ggacaaatac gatatataag agggtttcca atattaccag tagggtatat tcaacacaga
     2161 catccgatgt gtaaaaaaag aaatattaat aaatacaccg aagaaggtag ggaagccatt
     2221 cataagaagc aacaaaccgt agaagaatgg aagatatcgt ggttgtgtag caatccagtg
     2281 cttagtaaga gagcaacgat tgaatttgcg gacaatcgaa tttcaaaatt catcgctcaa
     2341 aagggaagat gtgcagtaac aggtgaggag cttatcttat ctgaaatgca ttgtcatcat
     2401 attatccctt atcatgaaag caaaagtgat agctatgaaa acctagtgat tgttactgag
     2461 gaggttcatc gggtaataca cgctacacaa agtgaaacga ttgaggaact tctaaaatat
     2521 ctaaaattaa atccaaaaca aaaagaaaaa ctcaatgagt tgagattaaa agttggtaac
     2581 gaagaaatat cttaataaat atttgtagga cgggaaaaca gaatgtcttt tatagacgag
     2641 ggaacgccgt atgcggtgaa agtcgcacgt acggtgtgga ctgggggaaa agacggagat
     2701 aatat
//
LOCUS       DACDLM010000157         2675 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.165, whole genome shotgun sequence.
ACCESSION   DACDLM010000157 DACDLM010000000
VERSION     DACDLM010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2675
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.165"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            20..316
                     /locus_tag="IV356_002910"
     CDS             20..316
                     /locus_tag="IV356_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016518.1"
                     /translation="MNVKIRDLDPKFISEIDRRCVELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQEKFDQLLEKFSEIQSYNTKILEEYVSQNNRIIEILIEQNRGSEL"
     gene            318..740
                     /locus_tag="IV356_002911"
     CDS             318..740
                     /locus_tag="IV356_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016519.1"
                     /translation="MAKVIDKHIYFHQTHIDVLDETISTHAEVKNYSEAVRFLCMNYD
                     PEVEKKVNSNQAKLNGMSKEISILTEMVSEFADLHLKDTGILIGKNSTVYQEAKERVE
                     GKIKSNQTKKYSPQLKKPVNESVHARVDPFDPTKILKR"
     gene            759..2351
                     /locus_tag="IV356_002912"
     CDS             759..2351
                     /locus_tag="IV356_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016520.1"
                     /translation="MTQSPSVILTCQFTLPNKKSFSTYIDYITREQALEEKERRTPEE
                     EQELQRIKNALEEFYIPEGETFSESKTGKEFSETSNEAQSLMEHGINFDKLEEQDFTN
                     YLSYMTRHYALEQKKELTQSEQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSIASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPDKRSEWNYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQ
                     ISKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            2372..>2675
                     /locus_tag="IV356_002913"
     CDS             2372..>2675
                     /locus_tag="IV356_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016521.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVNGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKS"
BASE COUNT         1079 a          389 c          524 g          683 t
ORIGIN      
        1 attatattgg aggatattta tgaatgttaa aattagagat ttagatccaa aattcatttc
       61 tgaaattgat cgaagatgcg ttgaactaag taatcgtaca ggaaataaat ggagtcgtaa
      121 tgattattta aagctactcg ttgaaaatga ttttgatcgt cctttgatgg aatacaaaca
      181 agaaaagttt gaccagttat tagaaaagtt ttcagaaatt caaagttata acacaaagat
      241 attagaagaa tatgttagcc aaaataatcg tattatagaa atcttgattg agcaaaatag
      301 aggaagtgaa ctttgatatg gcaaaggtta tagacaaaca catttacttt caccaaacac
      361 atatcgatgt attggatgaa actatttcta ctcatgcaga ggttaaaaac tatagtgaag
      421 ctgttcgctt tttatgtatg aactatgatc cagaagtgga gaaaaaagta aattccaatc
      481 aagcaaagtt gaatggaatg agtaaagaaa tttctatttt aaccgaaatg gtttcagaat
      541 ttgcggatct tcatttgaaa gatacaggaa tattaattgg taaaaattca actgtttatc
      601 aagaagcaaa agaacgagtg gaaggaaaaa ttaaatccaa tcaaacaaaa aaatattccc
      661 ctcagttgaa gaaacctgtg aatgaatctg ttcatgccag agtagatcca tttgatccaa
      721 cgaagattct aaaaagataa aaatgaagga ggataataat gactcaatcg ccttcagtta
      781 ttctcacttg tcaatttact ttgccgaata aaaagtcatt ttctacttat attgactata
      841 ttacaaggga acaggctctt gaagaaaagg aacgacgtac gcccgaagaa gaacaggaac
      901 ttcaacgaat caagaatgct ttagaggagt tttatattcc tgaaggagaa actttttcgg
      961 agagtaagac gggtaaagaa ttcagtgaaa cgtcgaatga agctcaatcg ttgatggaac
     1021 atggaatcaa ttttgacaag ttagaggaac aagattttac caattatctt tcttatatga
     1081 cccgtcacta tgcgttagaa caaaagaaag aactgacgca aagtgaacaa aaagaatacc
     1141 aacgcttgaa ccaagcaatg aaaaaatatc aaacagaacc ccataaaaaa gcttcaggaa
     1201 atcttcctgg agttttttct atagcttcag acgaagtgaa aggaagtgat ctgaaggaga
     1261 ttaagcaaat cttccaaaga ggacaacaaa aaggctcaat catttatcaa gatgttgttt
     1321 ctcatgataa ttcgtatctt gaaaaaatag gattgtacga tcccaaaaca gatactttag
     1381 atgaagaagg gttaaaagca gctggaagaa aaatgatgga gacattattc gagaaagaac
     1441 aattgaatga aacaggttac tggatggcaa cgattcaccg taacactaaa catatccata
     1501 ttcattttgc agttgttgaa aaagaaaata cgcgtaaacc ttacacggag gttgaaaatg
     1561 gtgtgagtta tatcgtaccg aaaggtaaga gaagacaagc aacattagac gcaatgaaga
     1621 ccaattatgt acatgagtta gaacgttttt cttatgaaaa ggatcgaatg attggtatgg
     1681 agaaacgaaa tttattgacg cggaaaagtg atttgcgtaa caccttaaca aaagtggtaa
     1741 aagagccagc gcgttacgat cgacacgcga tgaacttatt aaatgaagta tataaaaccc
     1801 tacctgacaa acgttcggaa tggaattacg gggatgaaaa acgaaccaaa ctttcaccat
     1861 acacaagaga gaaactcgat gagttaacca aatatgtttt aacaaaagaa cctgaatatc
     1921 aagaatatat acagatttca aaagcattga aagaagaagc aaaaagtctt tatggggaaa
     1981 gcaagagaga atcaaaggat gcagagaaaa atgctctctt tgatttaaaa aagcgcacag
     2041 gaaatgccat cctaacagag ctgaagagac aggatagtca aataaaacca ttaatagaaa
     2101 gtgttgatca gatgcaatct atttacaatg aacgatcctt tcgaacgctt aaacaattgc
     2161 caacgaatga atacaaatat agttacgaag aattcatgaa gcgcaggaaa caattccaac
     2221 aaagagttgt cacgcagcgg agtttgcgtc aattaaatcg aacgattaat gcccatgaag
     2281 aaaaatacca cgcaagtaaa gcatacgaag agcaacaacg aagaattcaa atggaacaag
     2341 aaagacagta aagacagtag gaggaatagc aatgaaacaa tatttagatc aatggaaagt
     2401 tatagaagga tcattaagag aagaacgaat cgaacaactt cctgattgtt tagaaaaaga
     2461 gcatttgttc cagataagag aaatgttgag aaacgaacag tttgatccaa atcaattttt
     2521 agtcgttgag tacccagcta ctggtgtgta ttgttgtaat catgtgaatg gtgaaaaata
     2581 ttttatcatt caagaatatg agggcaagtt agcaccttat tatactactt gggaaatgaa
     2641 tgaagaggga atcaataact ttccatgtaa aagca
//
LOCUS       DACDLM010000158         2634 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.166, whole genome shotgun sequence.
ACCESSION   DACDLM010000158 DACDLM010000000
VERSION     DACDLM010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2634
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.166"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            5..1150
                     /locus_tag="IV356_002914"
     CDS             5..1150
                     /locus_tag="IV356_002914"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HAP9016522.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            1321..1779
                     /locus_tag="IV356_002915"
     CDS             1321..1779
                     /locus_tag="IV356_002915"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HAP9016523.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            1938..2408
                     /locus_tag="IV356_002916"
     CDS             1938..2408
                     /locus_tag="IV356_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HAP9016524.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(2461..2576)
                     /gene="rrf"
                     /locus_tag="IV356_002917"
     rRNA            complement(2461..2576)
                     /gene="rrf"
                     /locus_tag="IV356_002917"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          862 a          505 c          496 g          771 t
ORIGIN      
        1 aaacatgcac attcaaacaa aattgatcca cggaggcatc agtgaagatc ccacaacagg
       61 agctgtcagt gtacctattt atcaaacatc cacttatcgg caagatggcg tcggccagcc
      121 taaacaatat gaatattcaa gatctggtaa tcctactcgt tttgcattgg aagaactgat
      181 tgctgatttg gaaggcggtg ttcgaggatt cgctttttct tctggtcttt ctgggattca
      241 tgccgttttt tctctttttc aagctggcga tcatatctta ttaggagatg atgtctatgg
      301 aggaacattc cgtctatttg acaaagttct tactaaaaat ggtctcgagt acacgatcat
      361 agatacgagt aatcttgata aaatagaaca atccatcaaa cccaatacaa aagcacttta
      421 tcttgaaaca cctagcaatc cgcttctaaa gattactgat ttagaaaaaa gtgccactct
      481 ggctcatcaa catggattga tagttattgc tgacaataca tttgctactc cttattttca
      541 aagaccttta gatctcggtt ctgatatcgt tgtccatagc ggtaccaaat atctaggcgg
      601 acacagcgat gtagtagctg gtttagtgac ttctaaccat aaagatctag ccgatcagat
      661 cggattttac caaaatgcta tcggagccgt acttggtccc caagatagct ggttacttca
      721 gcgcggaatc aagacactaa gtgttcgtat ggaggaacat caaaaaaatg cttttgtggt
      781 agctgatttt ctattttctc atccagcagt agaaaaggtc tactatccag gattacccga
      841 tcatgaactc catggagttg ctaagcagca gatgagcggc tttagcggaa tgatttcttt
      901 tactttaaaa aatgaagaat ctgctattcc atttgttgaa tcactccaac tatttacttt
      961 agcagaaagt ttaggtggcg tagaaagttt agtggaaatt ccttctgtca tgactcatgc
     1021 gtctattcca aaagaaaaac gagaagaggc tggcataaag gacggcttga tccgtctttc
     1081 tgtaggaatt gagtatggtc aggatctcat aaacgattta gctcaggcat ttgacagaat
     1141 caagaactag aagtcccaat aaacgactta gcagaaaaat ctaaaaaata tttcagattg
     1201 ctacaccttg gaaacgataa gtgttagaat caagtagaaa gacgtttttg taaatttcac
     1261 taaataattc tttagtgaaa agcatcaaaa cgaatgaaca aacagatagg agtcttacaa
     1321 atgagaatga atgtcgaaag ttttaatctt gaccatacaa aagtcaaagc accttatgta
     1381 cgtgtagctg atcgaaaaac gggtgcgcat ggcgatgtca tcattaaata cgacgtccgc
     1441 tttaaacaac caaataaaga acacatggac atgccaagtc tacattcact tgagcacttg
     1501 actgccgaac taatccgcaa tcacgcagat tacatcgtag actggtctcc aatgggatgc
     1561 caaacaggct tttacttgac tgtattgaat catgaaagct acgaagacat tttagatgtt
     1621 cttgaagcaa caatgaaaga tgttcttgaa gctactgaag tacctgcaag caatgaaaca
     1681 caatgtggct gggctgccag ccatacacta gaaggtgcac aagctttggc tcgtgaattt
     1741 ttagcaaaac gcgatgaatg gtctgaagta gaagcatagt ttctaaaaga acgtaaagat
     1801 gagaagcaat atagctatct tatcttcgta ttttattaaa tatttattgt ctgaaaagag
     1861 ttctaaacgg gaaaacaaat agctagtttt cagtttagcg ctctttttat tatataaaat
     1921 agaaaggaga aaactttatg tctatttata attttgaaac tactttagaa gacggcactg
     1981 tctattcatt gaaaaaatat gcaggcaaac cgataatcat tgttaacact gcaacaaaat
     2041 gcggtctagc acctcaattt aaacaattag aagaacttta ccaagcttat cagacacaag
     2101 gtctggttat cttaggcttt ccttccaatc aatttaaaca agagctagat tcagcgactg
     2161 aagcagcaga agcttgtaaa accacttatg gcgttacctt ccctatgcat caattgattg
     2221 acgtaaatgg agaaaataca gatcctcttt ttacttatct taaaaatgaa gctcctggta
     2281 ctgtcactaa agcaataaaa tggaatttta ctaaattttt gattgataga aatggcaaag
     2341 taatcgaacg atttgcacca caaacttctc cattgaaaat gaccgctgca attgaatccg
     2401 ttctttaact taataaaaat aaaaaaagat gaactatttc tagttcatct ttttgccttt
     2461 gcgtggcgac gtcctactct cacaaggggc accccctcac tacaatcggc gctaagaagc
     2521 ttaacttctg tgttcggcat ggttacaggt gtatccttct cgctatcgcc accacactgt
     2581 ggtgttatct tttattgagt aaattttgtt cactcaaaac tggatttgaa gtca
//
LOCUS       DACDLM010000159         2570 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.167, whole genome shotgun sequence.
ACCESSION   DACDLM010000159 DACDLM010000000
VERSION     DACDLM010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2570
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.167"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..766
                     /locus_tag="IV356_002918"
     CDS             <1..766
                     /locus_tag="IV356_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="rotamase"
                     /protein_id="HAP9016525.1"
                     /translation="VQDFYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEY
                     NEQIKKLGPNYKEQLKAVGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFY
                     PEVSTQIILFSTKEEADKAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEI
                     PTEVKKAAFKLKNGEVSDIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIA
                     TEAKTLDTEFMDKTIRKVMKKDNVTIKDPYVKNIFK"
     gene            complement(1350..2045)
                     /locus_tag="IV356_002919"
     CDS             complement(1350..2045)
                     /locus_tag="IV356_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HAP9016526.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGAYYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(2029..2427)
                     /locus_tag="IV356_002920"
     CDS             complement(2029..2427)
                     /locus_tag="IV356_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAP9016527.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
BASE COUNT          859 a          458 c          386 g          867 t
ORIGIN      
        1 agttcaggat ttttatgata acccaaaagt taaatcaaat aatcaaacac tattaaaaaa
       61 aatgattgtc ttcaaagcat ttgatgatgt atacggaaaa gagatttctt caaaggaagt
      121 aacaaaagaa tataatgaac aaatcaaaaa actcggtcca aactacaagg aacaattaaa
      181 agcagttggc caaacagaag agacatataa gaaactcttt aaacagatgc tggctttcca
      241 atacggtttg aaagccaatg taaaattaac agataaagat ctagacactg cttggaaaga
      301 attctatcca gaagttagta cacagatcat tctattttcg actaaagaag aagcagataa
      361 agcaaaaaaa gaagcaaatg aaggggaaaa tttctccaag cttgttcaag cttatggaaa
      421 aaataaaaca ttaaaggaaa ctgatggaaa aatgaatttt gattcaacca atccagagat
      481 tcctactgaa gtaaaaaaag cagcatttaa actaaaaaac ggggaagttt ctgatatcat
      541 tcctgtaaca gatccaacga cttatcagca aagctattat ctagtaaaaa tggtaaaaaa
      601 acaggataaa ggttctaata aagacaaata caaatctgag ctagaaaaaa ttgctaccga
      661 agcaaaaact cttgatacgg aattcatgga taaaacaatc cgtaaagtga tgaaaaaaga
      721 caatgtaact attaaagatc cttatgtaaa aaatatattc aaataaacaa atttgaccca
      781 attggggatg tggcaaaatt tgagaagtga tttttggaaa ttccttctta tttttgaggc
      841 aaaccacttt tgccacaact tcatcggggc ctttttttat ttgtaccaaa acaaatcact
      901 ggatttgtta caatcatgag gatataattt aaaaaagttt tttatttcta tcacatgaat
      961 cactgcgcca ttaagtagat tctttcatgc ttccctattt tttcacttgc cgtatcgctt
     1021 caaaaacaac tatcataaac tcaaactcga ctgaaaagtt attttaaaaa agactaaaaa
     1081 tatcccttct ggacttgttc ttcttattct gttatactag agaaacacga aagatatttt
     1141 tatgcgacac ttttcatttg tttttatgaa atttattcaa aactggcgta acttcagagt
     1201 tacaaggatg tattagaggt tagggaatac atcgtttaaa tgagaaataa gtaatagtca
     1261 cccaaacttt aaattaatga atattgaatc gtcagatagc ctcctcgagt tttcgagaag
     1321 gctatcgttt attttatgga gaaattgatt cagaagtaat cagcgacctt ttttagttca
     1381 ccaatcgttt ctgcttggaa agtttgcacc caatcttctt ggaagcccct cactgcttta
     1441 tcaatcgagg gcatctctaa tacttgatct agtagctctt tacctaacgt tatcgcatga
     1501 gctccagatc gaatggctgt agtgacttgt tcacaatttt tgaaactagc tgctaatatt
     1561 tttgttggtc tttgcgtacg ttcgatctca gtccgcaacg aatcaatcac tttcatagca
     1621 tcaatgcctt gattttgcat cctgttataa taaggtgcaa tataatatgc tccattatta
     1681 atagctaaat acccttgtaa ttctgtgtaa atagctgtac cggtaatcaa ataaccttct
     1741 tttttcaact ttttgatcgc ttgaaggcct gcttgattca ccggcacctt gataaacgta
     1801 tcttttccca gttcttctat gataactcga gcatcctcta tcatttcttc ttccgttctt
     1861 cctattgtct gaatatggat aggaatctgt ccgattattt ttttgatttc tttcatatgc
     1921 gagaagaagt ttgacgctcc ttcttttttc agaattgtag gatttgttgt tacgcctgtt
     1981 aaattcaaaa actgttgaca agaataaata ctttttgtat ttgctgtatc aagcatgatt
     2041 tccatatagc tttcccccat tctgatcctc ttgatcgatt ttaatgattg tcccctttct
     2101 taaatgcggc atttccttat cttctacata cattgttcct ggaagttccg gctcatgaga
     2161 tccatcaaat tttatcgtga tatgtcctaa ttcattcaaa ttagtttgga caacatctcc
     2221 tactgctgtg attacataca tttgtttatc aaaacagagc ttcatatcac aagttatttc
     2281 ttttcttacc tgattcaatt caatcttata acaataatct gttaatgttt ccggtgcttc
     2341 atctccaaat aaaatcatta ttttttcttt cctgaatact tctgcttcta taccaacatc
     2401 tgttacaacc gtttcaaaga tcgtcatctc tgttcctcct cgtaaaatat catttgtcta
     2461 atagttttta ttcaaaatgt ttctagatta taaaatttat tgaataacac attcctaacg
     2521 gaatttgttt cgatattgtg tgatttctca gagtacaatg gatgtatgga
//
LOCUS       DACDLM010000160         2515 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.168, whole genome shotgun sequence.
ACCESSION   DACDLM010000160 DACDLM010000000
VERSION     DACDLM010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2515
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.168"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..340)
                     /locus_tag="IV356_002921"
     CDS             complement(<1..340)
                     /locus_tag="IV356_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /protein_id="HAP9016528.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLD"
     gene            597..1067
                     /locus_tag="IV356_002922"
     CDS             597..1067
                     /locus_tag="IV356_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HAP9016529.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            1289..2392
                     /locus_tag="IV356_002923"
     CDS             1289..2392
                     /locus_tag="IV356_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAP9016530.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLRDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
BASE COUNT          844 a          406 c          564 g          701 t
ORIGIN      
        1 gatctaaaaa tcgggaaagt gaagattgag aagcgagttc tttcctatct aaaacagctt
       61 taaacacagg atcttgtctc aggagattag ctgcagaatc agctgagtaa ccagcaatta
      121 attgcataat gaactgctca agtatggata agttgtcatg agtaaaatac gctcgttcgt
      181 cttcaatgtg aatgtgttgc ttagccagtt cagaaaaacc aaagatgttc atcagctctt
      241 tcactaggac gagacccgaa tcactcgata attgaccacc tgtatgagaa atagtgatat
      301 ttgaattgaa ttttacttgg tttttgtgta agctagtcat gaaaagaact cctttctttt
      361 ggttggttta gtcactttaa ccatagcaga aaggggttct tttttcatca cttaacgggt
      421 gaagatgaaa aagtaattgt aagctgccgt gaggcagttt cacatggttt taattaaaag
      481 tatgaattat tcaggtagaa tctctgaaga ataaatcacg tgatcgtgac gataaaatac
      541 acttacgtca ggtgataaaa aatacataag tagaaaacta agaggaggaa cagaaaatga
      601 aagaagttca attgatcaga aaaagcgaac tatcagaagg tggttgcaat gcatgcggcg
      661 tagtagaagc aacaagctat acattaaagc ttggtgccaa caaagcgata atctctgagt
      721 tgacagtagg cggtcttgtg gacagtctgg cgcttgctga aggttttatt ggagaagata
      781 tttatgagat gttttcagaa atccgtcagt taaaaaaagg ggaaaactgc atagaggttc
      841 atcatgagag cccgaatgtg agattcaaac gtggtgataa tgagatgatc ttcaataatc
      901 atgtgtccga tcacaccgag ctatatggaa tcgtgaatca aatactaact gagctttttg
      961 gattgggacc ttatgcgttc aaggaagaaa acggtaatcc aaaattaaac gaagaatggc
     1021 aagaaacgat tgaaatacaa agaaacaacc cgcacttatt tcaataggca tccacagtat
     1081 ttcgtaaaag ggactttgac acgacttttg tcaaaatccc atcgtttttt atctatttgt
     1141 gttctaaaca tttctttcag agtagtaaca actggaatga ctgaaatgta aacagattat
     1201 ttgcctgtat caatacggaa gagtaatata aagtgtgtaa acgctatcat attattcatt
     1261 caatttttta tagagggaag gcattgaaat ggaaaaaacg tatcaagcag gtacaaatga
     1321 aggaatagtg gattttatca atatggaaga tttagaaata gccgcttcac aagtgattcc
     1381 agctggtggt tatggttaca tcagcagtgg tgctggcgac ttatttactt atcaagaaaa
     1441 tgaacgggca ttcaatcatc agctgattat tcctcatgta ttaagagatg tagaattacc
     1501 cgatacaact acacattttg acaaagaaac gctgactgca ccaatcatca tggcaccagt
     1561 tgctgctcat ggcttagctc atgtgaaggc ggagaaagct tctgcaaaag gtgtagcaga
     1621 ttttgggacg atctatacag caagttctta cgcttcttgt acattagaag agataagaga
     1681 agcaggcggg gagaaagcac cgcaatggtt tcaattttat atgagcaaag atgatgggat
     1741 caatttggat attcttgaag tggccaagcg taatggagca aaagcaatcg tattgacagc
     1801 ggatgcaaca gttggcggaa accgtgaaac agaccgcaga aatgggttta ccttcccact
     1861 gccaatgccg atcgttcagg cttatcaatc aggagtaggc caaacgatgg atgctgtgta
     1921 caaatcttcc aaacagaagc ttagtccaaa agatgtagaa tttattgctg ctcattctga
     1981 tttgccagtc tatgtgaaag gtgtccagtc agaagaagat gtctatcgtt cattagaatc
     2041 tggtgctggc ggaatctggg tatctaatca tggtggccgt caactagatg gtggtccagc
     2101 agcgtttgat tcgttgcaat atgtggcaga agcagtagat aaacgtgtac caatcgtgtt
     2161 tgacagcggt gtacgacgcg gacagcatgt tttcaaagca atcgcatcag gtgcagatct
     2221 tgttgctatt ggcagacccg ttatttatgg attgtcttta ggaggaagta caggagtcca
     2281 tcaagtgttt gatttcttta aaacagaatt ggaaatggtc atgcaattag ctggaacaca
     2341 aacagtagaa gatatcaaaa aaataaaatt gcgtgagaat cgttttattt aagaaacaaa
     2401 tgacgaaaaa aataggagtg cggcagatga tgccgtactc ctatttttat agttcaagga
     2461 tgtcactaat agaataattt gaaacgaaaa aataaaattg aaatattttt tcata
//
LOCUS       DACDLM010000161         2483 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.169, whole genome shotgun sequence.
ACCESSION   DACDLM010000161 DACDLM010000000
VERSION     DACDLM010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2483
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.169"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(1014..1304)
                     /locus_tag="IV356_002924"
     CDS             complement(1014..1304)
                     /locus_tag="IV356_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016531.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1512..2203)
                     /locus_tag="IV356_002925"
                     /pseudo
     CDS             complement(1512..2203)
                     /locus_tag="IV356_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
BASE COUNT          734 a          458 c          348 g          943 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattac tgttgcttct ttactaattt aggtttactt
     1501 gttaagaaag attatttacg caaatgttct tcaacaattt gctgagattt atcagctgta
     1561 tcttccactt catcttttgc tttttctaac ttttgaatat attgtttcaa gcttgagttt
     1621 tcagcagttg cttcgtctaa tttcttttgt gtatctgtta actgatttct acatttgttt
     1681 tttcttgtgt cagtgttgcg atttgttgat tcaaaccatt tacagtattt tgtaattctg
     1741 aaagttttgc ttgtgcttct tgtagtcttg ctgtccaatc tgcattcaga tgattgattt
     1801 catcattttt ttggttgatc tcatctagtt tgacattgat ttcattttgt ttgctttgta
     1861 gttgtgcatc cttgctgact aattgacttt ctaagttttg tttttctgct gccgattgat
     1921 ttttttggtt ttctaattca tttacttttg tttggtattc ttggacatct gcctttgaat
     1981 cttgcaatgt ctgttctttt tgtgctagtc gagcggtaag atctgtaatc gcttgctctt
     2041 tatctgtcaa tgtatgatca agctgtgtca gattctcatt gattgtatca atatctgtct
     2101 ctccacccca caaaataatt tcatttgcgt accgcgtgcc tgtgtagcca attagacata
     2161 gaaatgcaac gacaatccca ccagtaataa atttcttttt catttgcata gctccttaat
     2221 ccaatacttt tacatgctaa aagtaagtga tctcaaacac aatgtcaagc gtttttaaat
     2281 tacatatgta attttaatat aaatactatc aaatactcat ttaatcctcc ttttttatct
     2341 atttaaaaaa tcttttttat agagaaaaat gcaggttaat actttcttaa ataaatattt
     2401 atggtgaaca aaaacaaaaa agcaagtttt attaaacgta acccttttca tttcatagat
     2461 tactgtattt attacaaaaa acg
//
LOCUS       DACDLM010000162         2400 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.170, whole genome shotgun sequence.
ACCESSION   DACDLM010000162 DACDLM010000000
VERSION     DACDLM010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.170"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            207..2069
                     /locus_tag="IV356_002926"
     CDS             207..2069
                     /locus_tag="IV356_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP9016532.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2400
                     /locus_tag="IV356_002927"
     CDS             2069..>2400
                     /locus_tag="IV356_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP9016533.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          866 a          353 c          466 g          715 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataatta
//
LOCUS       DACDLM010000163         2333 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.171, whole genome shotgun sequence.
ACCESSION   DACDLM010000163 DACDLM010000000
VERSION     DACDLM010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2333
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.171"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(142..1086)
                     /locus_tag="IV356_002928"
     CDS             complement(142..1086)
                     /locus_tag="IV356_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAP9016534.1"
                     /translation="MDTILITGGAGFIGSTLANYLGKENKIVVVDDLSMGKKENLDMD
                     KQVTFIEGDVSDSQLMERIMKEYQFAYIFHLAAVASVADSVERPVETHRVNFDSALLL
                     LELARKYQSNLKRLVFSSSAAVYGDEPTLPKKEESVIRPLTPYAIDKFAAEQYVLDYC
                     HLYDVPTSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQLAGEKAEFTLFGDGSQSR
                     DFVYIEDVIQALLLVAKEEKALGQQFNVGTGKSTTLLELIHSIDQILGTELALKYEAE
                     RSGDIRDSLADISKIRSLGYQPKFDILSGMERYLKTEI"
     gene            complement(1220..>2333)
                     /locus_tag="IV356_002929"
     CDS             complement(1220..>2333)
                     /locus_tag="IV356_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="HAP9016535.1"
                     /translation="ENIKLIMWQLIFFFMIYQFGKDYSSNFFFKVFTWILSLVWFLAN
                     LVSLYWFVIQYGIKIPIKYKYYPVRLGWLGNRLFGVYTDPNFGAVISLIVIIIAIYYL
                     VTYKHLNLLFKIFFVINIFIQFSFIALSGSRTTLVCLLITTFVFSFFTSYSSRFLKTN
                     TLKRWLTALVVGLLSIIAMYYVTDITAHAWAHVPHITEVKKDTSDSSGTTSSNKVDLK
                     RPDTDSGDVSNLRFELWKSAIEIFKSKPISGGSPGYYIEYAHNKLPYTLMGKDTLTAH
                     NFIFLVMAATGGLGLLTLLTFLFIQCFKALRYCFTQPNLVKDKHFFAILMILTIAVSA
                     LFITELILVSTIGSFIFWGYLGSIQKTISKEEGVTN"
BASE COUNT          810 a          412 c          328 g          783 t
ORIGIN      
        1 aagttctctt tttcatgtaa aatatttaat tatatatttc ctaaataaaa agtaaaacaa
       61 gaattaaata gttggttata caactttaat tcttgtttta ctttttagaa ttatttatcc
      121 aaagatgcaa tcattttttc atcaaatttc tgtctttaaa taccgttcca ttccgctcaa
      181 tatatcaaat ttaggctgat agcctaaaga acgaattttt gaaatatccg ctaaggaatc
      241 acgaatatcc cctgaacgct ccgcttcata tttaagcgct agctctgttc ctaagatttg
      301 atcaattgaa tggatcaatt caagtagcgt agtgcttttt cctgtaccga cattgaattg
      361 ctgtcctaaa gctttttctt ccttggcaac aagtaaaagt gcttgtataa catcttctat
      421 ataaacaaag tctctagact gactcccatc gccaaataaa gtaaattccg ctttttctcc
      481 tgccaattgt tttttgtaac gatccactag aatcgaaatg actccgctat atggagagtt
      541 tggattttga tttggaccat aaacgttaaa aaatcggaca gcactagtcg gaacatcata
      601 taaatgacag taatccaaaa catattgttc tgctgcaaat ttatcgatag catatggtgt
      661 taatggacgg atgactgatt cttctttttt tggcagtgtt ggttcatcac cataaactgc
      721 agctgatgaa ctaaatacta atcgttttaa attagattga tatttccgtg ctaactcaag
      781 caataaaagc gcactgtcaa aatttacacg atgtgtttct acaggccgtt ctacagaatc
      841 tgccacacta gctacagcag ctagatgaaa aatataggca aactgatatt ctttcatgat
      901 tctttccatc aattgagaat ctgatacatc cccctcaatg aaagtcactt gtttatccat
      961 atccaagttt tctttttttc ccattgataa atcgtcaact actacgattt tgttttcttt
     1021 tcccaaataa ttcgctagcg ttgaaccgat aaaaccagct ccgccagtaa tcaatatagt
     1081 gtccatcaaa ttcactccaa ttgcacattt tcgtatcaaa taatattagt ttaccatttt
     1141 tatattgtaa aaactataaa atttgttgaa gttgggataa ctagttttct tttctacttt
     1201 catataccta aaaatagttt caattagtta ctccttcttc tttagatata gttttttgga
     1261 tagaacccag atatccccaa aaaataaatg aacctatcgt actaaccaaa atgagttctg
     1321 tgataaataa tgccgaaact gctattgtaa gaatcattaa aatagcaaaa aagtgcttat
     1381 cttttactag atttggttgt gtgaaacaat aacgcaaggc tttaaagcat tggataaata
     1441 agaaggttaa caatgtcaat agacctaatc ctcctgtagc agccatcact aagaaaataa
     1501 aattatgagc agttaaagta tcttttccca ttaatgtata tggtagttta ttatgtgcat
     1561 attcaatata gtagcctgga gaacctccgg atatcggctt actcttgaat atttcaattg
     1621 cacttttcca aagttcaaac cttaaattag aaacatcccc gctatcagtg tcagggcgtt
     1681 ttaaatcaac tttattgctg ctagttgttc ctgatgaatc agatgtatct ttttttactt
     1741 ctgtaatatg cggaacatgt gcccatgcat gagcagttat atctgttaca taatacatcg
     1801 caattatact tagcaatcct actactaatg cagttagcca tctttttaaa gtattagttt
     1861 taagaaaacg actactataa cttgtaaaga aactaaaaac aaaagttgtt attaataaac
     1921 aaactaatgt ggtgcgtgaa cccgataaag caataaacga gaattgaata aaaatattaa
     1981 ttacaaaaaa tattttaaat agaagattta aatgcttgta agtgaccaaa taatatatag
     2041 caataatgat gacgattaat gatataaccg caccaaaatt tggatctgta tatacaccaa
     2101 ataaacggtt gcctaaccac cctaaacgaa ctgggtaata cttatatttt attggaattt
     2161 ttatgccata ttgaatgaca aaccagtata atgatactaa attagctaaa aaccatacca
     2221 atgaaagtat ccaggtaaat actttgaaaa aaaagttact actatagtct ttgccaaact
     2281 gataaatcat aaagaaaaag attaattgcc acatgattaa cttaatattt tcg
//
LOCUS       DACDLM010000164         2315 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.172, whole genome shotgun sequence.
ACCESSION   DACDLM010000164 DACDLM010000000
VERSION     DACDLM010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2315
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.172"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(413..1084)
                     /locus_tag="IV356_002930"
     CDS             complement(413..1084)
                     /locus_tag="IV356_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP9016536.1"
                     /translation="MEPKDKYLDYARVNKDKFIETIIKGKIPDDEKDAVFMAGSPGAG
                     KTEVALGLAENYDNHVVIDADYFRAQFPEYNGKNSSVFQKASSWLVEQSLKYVLEHGY
                     SFILEDTFAILSAEKNIIRALKNNFRVTIFYVYQDPKVAWDFTRKRELAEGRHVPKEM
                     FINAFFKSRENIEKVKNRHPEVVLHIMIKDYQNDISEVHYAADNIQLVLPNTIYFKRV
                     GGGIT"
     gene            1607..2197
                     /locus_tag="IV356_002931"
     CDS             1607..2197
                     /locus_tag="IV356_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HAP9016537.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQKEGWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKKIRLYKLGFYDYYKKYGDPFS"
BASE COUNT          743 a          386 c          359 g          827 t
ORIGIN      
        1 taaatatgac ttaggtaaaa caatgagtga tccaattata aaattttatg gcgaataatt
       61 tagtaagcgc tacatattga atgatttaga aattttgaaa aagtagctag ttccttttat
      121 accagaaaag taaacctaat aaaaaacaca actaattttt agctgtgttt tttaagttac
      181 aataattatc tatttaatag tcttaattca ttaaaacaaa aaactcaact ttacaaggat
      241 atggtttaaa aaatttattt atccaaccca actagttttc gctgcttacg atttgcttca
      301 tctgctacgt acttcattac tgttttaaat tctttcgctg aggcgttttc tgataaatca
      361 gcgatacttt tattatactt cttcacgatt tgttgtactt gttctttctc agtcatgtaa
      421 ttcctcctcc aactcttttg aagtatattg tattgggtag tactaattga atattatctg
      481 ctgcataatg cacttcagaa atgtcgtttt gataatcctt aatcattatg tgaaggacta
      541 cttcaggatg tctatttttg actttttcaa tattctctct ggacttaaaa aacgcattga
      601 taaacatttc ttttggcaca tgacgtcctt cagctagttc acgttttcga gtgaaatccc
      661 aggcaacttt gggatcttgg taaacataga aaatcgtaac gcgaaagtta tttttaaggg
      721 ctcgaataat atttttctct gcactaagga tagcaaaagt atcctctagt atgaaagaat
      781 agccatgttc cagtacatat tttaatgatt gttcaactaa ccaagaagaa gctttctgaa
      841 aaacacttga gttctttcca ttgtattctg gaaattgtgc tctaaaatag tccgcatcaa
      901 tcacaacatg gttgtcataa ttttcagcta aacctagtgc aacctctgtt ttacctgctc
      961 ctgggcttcc agccatgaat accgcatctt tttcatcatc agggattttt cccttgatga
     1021 ttgtttcaat aaatttatct ttattgaccc tagcgtaatc taaatacttg tctttaggtt
     1081 ccaagattgc accttctttc cttcttctat attcatacta attatacgat atttatataa
     1141 aaaatataac ggtcatttta accatattaa catttagtca cagtaatagc agatatgctc
     1201 gcaaaatgag atatgaatgt acgcagaatc cttgttttct acggcattcg ctgttttttc
     1261 attggactag ttatatattt ctagggttgt tttcatgtct gagtgcccga tatgatttat
     1321 ttttcgtttc tataattact ttttgccttc cagtttcttt taagattgta ctcaagcaag
     1381 tgggaattgg ttcttttgtc atccatgtat gcaaaatgtt ataatgctgg taaacaaaaa
     1441 tgattacctg tcatttttat ttagttcgta tttaattaag ttgactgtct gtatactctg
     1501 tctaaaactt aagaattgtt gttttcgctg tcgctatcca aatttaatga atgtctgtat
     1561 gttaaaactg ttgtccttgt catagatagt aaaggagagc ttgaaaatga aaactgcgat
     1621 tacgtttcta ttagaggaat atgccgattg ggaaggtgct tatattacta gcacactaaa
     1681 ccaaaaagag ggatggcaaa acaaaactgc ttctatccaa tcagaggtca cttccattgg
     1741 aggattaaaa acaaaaatcg attacttaat cgaacaaata cctgaaaaag ttgacctttt
     1801 tattatgatc ggtggcaatt catgggacat aaaaaatcat catttatatc aaataatcga
     1861 taaattgtta aaaacagacg taccagtagc tgctatttgt ggggcagttg attatttagc
     1921 tcagagcgga ttattgcaag gttacaaaca caccggaaat gcgcaatttc cttggttaga
     1981 atcggaaaat tatcagaata aagaagattt tatagaacaa caagctgtga aagatcgtaa
     2041 tttgattact gcgaatggaa cagctcctat agaattcaca gacttgattc ttcaagcagt
     2101 ccattttgaa acagaagaaa taagagaaaa aaagattcgt ctatacaaac ttggattcta
     2161 tgattactat aaaaagtacg gagatccttt ctcctaatca ttctcttcaa ttaaatactc
     2221 cttatcaata gtatgacaag taattttact gatggttatt tgtcacactt tttctgacat
     2281 ttatcaaaga agatacactc tatttatatt catag
//
LOCUS       DACDLM010000165         2312 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.173, whole genome shotgun sequence.
ACCESSION   DACDLM010000165 DACDLM010000000
VERSION     DACDLM010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.173"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            233..487
                     /locus_tag="IV356_002932"
     CDS             233..487
                     /locus_tag="IV356_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAP9016538.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            488..805
                     /locus_tag="IV356_002933"
     CDS             488..805
                     /locus_tag="IV356_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAP9016539.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1364..2299
                     /locus_tag="IV356_002934"
     CDS             1364..2299
                     /locus_tag="IV356_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016540.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          834 a          315 c          439 g          724 t
ORIGIN      
        1 acctatagag gatgggcgac ttctgcctaa ttctgttaaa tggatgttaa cggaagtgta
       61 tggtgagtag ttcactcgta ttttgatatc gtttgtatat gttttcagcg ttctaagtgg
      121 cttattttgt ccaataataa tatggagtgg aatcccttaa gaaacaccgt tggcaattgt
      181 tgttataaca tgttataatt tattcatcaa aaactaaaag gagtgtgata acatgggaaa
      241 agaactaaag gttagaaaga tcggcaatag cgtgggagtg atccttccaa gctctcttgg
      301 attaaaaagc ggagacatta tccaagccaa acaagaaggc aacttattca tattagatac
      361 tactcaaata gcaaaagaac acgatcgcaa attgattgaa gaaagtttcc aagactttga
      421 gaaaggttta acagtttcag aaattgaaat ggtaaaagct ttcggaaaat acggctggag
      481 tgaatagatg aaagagtaca cgctagttta ttctaaaagt tttcagacca gccttgaaac
      541 gataatagaa gaatgggaaa atgagcttgc tctttctcca gccagcataa aaagatttgt
      601 aggtgcgatc cagaaggctt tagaactaac caaaaatttt ccaactatgc atgaggaagt
      661 ttccgaaatc tatggaatgg atatcccaac atatcggatc gtgatcggca aaagctatgc
      721 cttattttat cggatcgacc atgaaaaaaa agagatactt gtaggacgta ttttccaatc
      781 taaacaaatg aaactaggct tttaacaata attaggaaaa agtcgctcat cctctacagg
      841 tgggtgatta atgccgctcg atatggttgt taaccgtcgg ttactcgaag attgatatat
      901 aagacttagt acctttttat tttgctccat gttatggccg aaggtctaaa gatacaatca
      961 ttagtctaga gaaaaattaa gaaccgtagg aactacgggg atcgcttggt gaataagaga
     1021 cactgctatt agtgaaaaaa taagatatca agtacgctct attcccaaaa atttcgtgac
     1081 tttactcatg agaggttcaa gtagtatatt tttaatcaaa attgacgtaa cttttaataa
     1141 atactaccta aataaggtag tatttatttt tgtgttttaa aagaggaagt ccaatatatc
     1201 tatgggaaac ttcttaaata ttatgttggt acatgaaaat atacatccct gctagactat
     1261 ttacaacatt ttactttgta cgtattcttg ttttaaaagg aatgggataa aatataggta
     1321 caataactat ttgatgctaa atataattaa tggaggagag atagtgaaca tacttaatga
     1381 aaaaagatat gtatggtttg ctggtaaaaa atatattact actttcaaaa gattatccga
     1441 gttaatgcag cagactgtta aaagtgctat gcctgaagga tacaagttta attttgttca
     1501 atcttcagta tctactgaaa gtatctattt ttcaattctt tctgagagta ggctttttca
     1561 ttttagaata agttctcatg taaagaaaac tgatgttgat atatatacgt tccgtacaaa
     1621 taattataaa aatttaaatg atttgagtag aagtatcagt gaatatctca aggggaatag
     1681 ctatctcaag attcgatttt cacatatatt aattttacta ccatatttga atgagaattt
     1741 caccctaatt caagtagata agtctttcat tgcctcaggt aatcaaggaa atatgaatat
     1801 tacaagtaac aaaacgtcac gtgtgctatt ggcgttgatg ggttacggaa ttctttatag
     1861 agatgaccaa aatggccaga ttctaataaa tcgggctggg cgttcattat taatgaaata
     1921 tagaaaattt ataccggaag attttcaaaa cttacagtta gaaaacatgc gtttagaaga
     1981 tttatttaga ttagcagaag atgataagta tagatttgaa gttttgaaaa ttcaaaagaa
     2041 tgaactattg aataagttat atcctgagaa tgcgataaaa gcacattttg gtgatgctaa
     2101 tcatatgtat agttggttca ttcctaaaag atttagaggg aaaatcaatg ctggagatca
     2161 agtgaaagta ctcaatcgaa atagtacaga tgtcgtaatg ataacagata tctatgtaga
     2221 agatgaagat ataatcaaat atatgaagcc tgtgataaaa cttgttaata aaaataaagg
     2281 aacccgtggt gctagttaat tttttcctag ag
//
LOCUS       DACDLM010000166         2232 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.174, whole genome shotgun sequence.
ACCESSION   DACDLM010000166 DACDLM010000000
VERSION     DACDLM010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2232
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.174"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..378
                     /locus_tag="IV356_002935"
     CDS             <1..378
                     /locus_tag="IV356_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HAP9016541.1"
                     /translation="KNVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFR
                     RFPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTD
                     DWQKVMAAEVIATYLDGDLVYKK"
     gene            426..1826
                     /gene="yfcC"
                     /locus_tag="IV356_002936"
     CDS             426..1826
                     /gene="yfcC"
                     /locus_tag="IV356_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HAP9016542.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
     gene            1859..2026
                     /locus_tag="IV356_002937"
     CDS             1859..2026
                     /locus_tag="IV356_002937"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016543.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAFTGSVAKF"
     gene            2080..>2232
                     /locus_tag="IV356_002938"
     CDS             2080..>2232
                     /locus_tag="IV356_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAP9016544.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVREILYDRGINVSH
                     TTIYRWV"
BASE COUNT          628 a          371 c          483 g          750 t
ORIGIN      
        1 aaaaatgttt ccacagagga cttctttaat tattgtcgat tagaggaaag tggtgtaaca
       61 gtcactagcg gtacagattt accgctgttt attactgata ttcctgaatc gattataaga
      121 gcagtattcc gtcgttttcc tgaaggagaa gaagtctggg agaaagaaac aagcttcacg
      181 acaaccgagc tgctgaaaag ttttacaagc aacagcttca aagtaaatgg tttatcggag
      241 tacggagaaa taaaagtagg gaaaagcgcc agcttagctg ttttcagcga ggacctctgt
      301 actgatgact ggcaaaaagt gatggctgcg gaagttatcg ctacctatct tgatggtgac
      361 ttagtttaca agaaataatg cttttcgata taacgttata aaacgaatta aagagaggtt
      421 aaaaaatgga aacaatgaaa agaaaattca ccttcccaca tagttataca ttgattttta
      481 tcttaattat tttggctgca attttaactt ggataattcc tagtggtcag tttgagacag
      541 ttgttgaaaa cgtcgcaggt atggaaaaaa caacggttgt tccgggaacc tatcaccaaa
      601 tcgataaggc agattatgga caaggttttt cctctatact aatggcacca gctgaaggga
      661 ttatttcagc tgttgaggtt gttgcttttg ttctcatcgt tggtggtgcc ttcgggatta
      721 tcctaaaaac gggagccatc gatcgagggc tgtttacctt agcaaaagtt ctgggagaca
      781 aggggatctt agttattccg atgtcgatga ttctattcag cttaggagga tcaacctttg
      841 gcatgagcga ggaagtcatt cccttatttg cggtgtttat ttctctgatg ttttctcttg
      901 gctatgattc catgactgcg atcttgattc tatttttaag tacacaagcg ggatatgttg
      961 ggtcgacgat taatcccttc aacgttttaa tcgcacaggg agtagctggc gtttacggaa
     1021 atcccctgct ttggtttcgg atgctatcct ggattgtcat tactgggatt tcaattgttt
     1081 tcaccatgct ttatgctagc agagtcaaaa agaatccact gtcctctatt gtttatgaga
     1141 gtgatttaaa ggttaagcat aagtttcaaa attttgacac tgaaaaagag ttttcaacac
     1201 aagataaact aattatcgcc ggttttatcg taggtttagg aatcatgatt tggggtatca
     1261 tttccaaggg atggtatatg gttgaaattt ctgcactatt cttaggatta ggtctttttg
     1321 ctgggggcat cgctagattt tctcaaaagg aaattgctga agcttttgtc gaaggctgtt
     1381 cagatttcgc ctatgctgct gtaatcattg ggctagctag aggagtcttg gtaatcttgg
     1441 aaggtggaat gattattgac actattctaa acagcttggc taacctttta ggtggtcttc
     1501 caaaattcct gttcactacg attctactca tttctcaagt aattgtttcc ttttttgttc
     1561 catcctcctc aggagctgcg gcattaacga tgccggttat ggcaccattg ggtgatctaa
     1621 tgaatgtaag tcgtgatgtt gttgttctaa gtaaccagtt tggaaatggt ttaatgaata
     1681 ttatctcccc aactagtggt gtattactgg caggattagc catcgcagag attaatttct
     1741 ctaaatggtt taaggttggc ttcaaaatat ttgccatctt aacccttgtt tctgctgttt
     1801 tgttatacat tgctacactc ttttagtctt aatcatccat taataggagg caatagttat
     1861 gattaaaata aatcaattag caggaatgaa tatccactat ttattttatt ctctcaaaga
     1921 atttttcgct tatcaacaga aaattggtat ttcttctgtt gaactttggg gaggtgctcc
     1981 gcattttttc atagatgctt ttactggttc tgttgcaaag ttttaaatct actatcaaat
     2041 aaggtagaat aatagaaaaa gatagcagga ggaatgacga tgaatcattt taaaggaaag
     2101 caatttcagc aggatgtgat tattgtagcc gtgggctact atcttcgtta taaccttagc
     2161 tatcgtgaag ttcgagaaat cttatatgat cgtggcatta acgtttctca tacgacgatt
     2221 tatcgttggg tg
//
LOCUS       DACDLM010000167         2115 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.175, whole genome shotgun sequence.
ACCESSION   DACDLM010000167 DACDLM010000000
VERSION     DACDLM010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2115
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.175"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..1493)
                     /locus_tag="IV356_002939"
     CDS             complement(<1..1493)
                     /locus_tag="IV356_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HAP9016545.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAET"
     gene            complement(1595..1948)
                     /gene="tnpB"
                     /locus_tag="IV356_002940"
     CDS             complement(1595..1948)
                     /gene="tnpB"
                     /locus_tag="IV356_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HAP9016546.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
BASE COUNT          590 a          447 c          375 g          703 t
ORIGIN      
        1 aaagtttctg ctgaaagtac gggaagattt ggtatcttat caaatagaaa ctctagatac
       61 tttacaggat tcaatccgtt aagttctgct gttttatata cactcagaat gattcctgaa
      121 gttcgtgctc cttcaagact tgtggaatgc aaccaatttt tccgtcctat caccagctct
      181 ttgatatttc gctccgcacg attatttgtg agttctaaac gaccatcttc aaaaataggt
      241 tcaaaaccac ttcgtagttt acacgcatat tgaacggctg catccaactt ggattttgca
      301 acaggatcta tcgttgccat ccactcataa aaagcaataa ataatggacg cagttcttgt
      361 tgccgacagc ttaatcgctt ctcaggagaa aagtctttcc atttcttttc taggacaaac
      421 catttatcca attgtttgac tgcttgagct gcgggaatat ccgtgttttt ctttcctttt
      481 ggaattgctt cgaaaaattt ccgccgaaca tgcgcgaaac aatagacaag tcgtacactt
      541 tccacggcat tatacccgct atagccgtca cagtgtaaat accctgtaaa ctccttgaga
      601 aaagttttcg gaacatctcc agcacgactt tcgtcgtggt gataataaac gatgggatgc
      661 tgactgtctt ttcctgtaca aaactgccag taataggtat ctgttttggc actttcaatc
      721 acacgataac ttgtttcatc cccgtgtaga atctcttctt gattaagata gactcttaat
      781 cgttctccta aagggtctaa cgcgttttgc actgctttaa tatgccaatt ggtgatatta
      841 tctctcgaaa tatccaaccc atgtgtttgt ttccaatagt tctcttgccg ataggcagga
      901 actttctgac caaatttcat ccggatcgtt tccgccacta aactattgga acctaagcta
      961 ttagaaatca aaggtttagg aacgatcgct tttttaaaag aagaaagtcc ttctttttcg
     1021 cagcttttac aacaataggt atgttgataa tgggtgagac aatccaacat agcctgatgg
     1081 aaacgaattt cttctcgtac ttttgtccgt ccgatatctt tcatctgtga accgcaatgt
     1141 tcacaaaatt gttcttccaa aggaaggaga tgttctttct ctgttatagg taagtgtttg
     1201 attttgtctg ctttcgttcc tacaactcgt tgatgtcctt ttactggaat aatggtggca
     1261 gctgcttctg gaacacttac agaaatttct tcatcactaa aaagattcaa ttgcccattc
     1321 gtttcctcaa agagagtctc tttagagcgt ccaaataatt tgttggttaa ataattgacc
     1381 ttttcattca atagttggat ttcagttgta agattctgaa tggtttgttg ttgtgcttga
     1441 ttggttttat gggcttcttg aagcaactga agcaacgtat ctgtagtttc caaaattttt
     1501 caccaccttg aatcgaactg attttgttac agaataccac aagaaacgca caagaaatag
     1561 gggttcaaca cattttttgt gttaaccccc cagcttaaaa aactcctttt tttcctggca
     1621 aaatagctcg aggttgatcg atacttaatc cttctaacaa ccatcgaacc tgttggttcg
     1681 ttaaggttcg aacttcgtct ttcgtccgag gccattttaa cttgccgttt tctatccgct
     1741 tataacagag aagaaaacca tcaccgtccc aatagagaag tttgaaacgg tcttgacggt
     1801 tcccgcaaaa taaaaaaacg gcatcttcgt aaagctcgag ttgatactct tgttgaataa
     1861 gactggcaag accatcaatt ccttttcgca aatctgtttt tccgcacaca atataaatat
     1921 gtttggtttg aagtaaatca taaagcattg gacaacagtt ctttcaaaat agcttgaaga
     1981 atataattgt taataccgtt atagatcaaa acttcagaac cattctctct tttgatgcgc
     2041 atcgctaact tggcagccgc gggtttacct ttttctggtg cactcttttc gtttcctaat
     2101 tggacaggaa caatc
//
LOCUS       DACDLM010000168         2065 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.176, whole genome shotgun sequence.
ACCESSION   DACDLM010000168 DACDLM010000000
VERSION     DACDLM010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2065
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.176"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            442..1059
                     /locus_tag="IV356_002941"
     CDS             442..1059
                     /locus_tag="IV356_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP9016547.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            1100..1399
                     /locus_tag="IV356_002942"
     CDS             1100..1399
                     /locus_tag="IV356_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016548.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            1433..1600
                     /locus_tag="IV356_002943"
     CDS             1433..1600
                     /locus_tag="IV356_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP9016549.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(1645..>2065)
                     /locus_tag="IV356_002944"
     CDS             complement(1645..>2065)
                     /locus_tag="IV356_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP9016550.1"
                     /translation="SLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGNELLD
                     TAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQKRLV
                     FKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
BASE COUNT          713 a          319 c          397 g          636 t
ORIGIN      
        1 gaatcaagcg acttcaaaga aaaaaagaaa gaatacaatt atattgtaaa ggcaaaagta
       61 tcaaaaagat ttatttttaa ccctaaatta gaaatatata gtgttgtaat agaataatag
      121 tgttaaaaaa attgtaaaag ttaaagaagt caaattctga tgtgaaaaat aaaatatacc
      181 atggaagaca taaaagaaaa actggataac tagtttattt aatggcagac cgttaaggcc
      241 tgccattttt atgtatttta gcggaataaa tataatcatg cgggagtgta aacttactgt
      301 ttcaaaaagt atactttttg acatgccttg attttctttg tttatgtatg gcataataac
      361 cacataatac aatttgaaac gtttctgatt taatctgatt gttttgaaac aattttagtg
      421 aaaaaagggt agataaaaac gatgagaaaa tttttttata tccgggtcag tagttatgat
      481 caatcgatcg aacgacaact gatttccgcg aaggaattag gaatccctga agaatatata
      541 tttgtagaaa aagccagcgg caaagatttt aaacgccctg aatatcaatt aatgaaacgg
      601 atgtttcgaa aaggagattt actctatcta caatcattag atagactagg cagaaataaa
      661 caaatgattt tagaagaatg gcgagaatta actaaggaaa agcagattga tatttctgtg
      721 ttagacatgc ctctgttaga tactgctagt tacaagcaac tagatgggtt agagacgctt
      781 atctctgact taattctgca attactcagc tatatggccg aagacgagcg gaaacgaatt
      841 aatagccggc aaagagaagg cgtagaagct gcgaaacaaa agggtgtaaa attcggcaga
      901 aagaaaattg ctttacctcc tgaatttcct gcgatctatt ctgactggaa agcaggaaag
      961 ataactgcag tctatgctat ggatcaattg ggcatgaaac gaaatacctt ttatcgacgg
     1021 gtgaaagaat atgaacatac cttgcaccac ttttcttgat agatataaca gctattagac
     1081 gggaagggag agtttgaaaa tggacttaac gaatcaaagg gtcgttttta ctggaacgct
     1141 gcagcaaatg acacgaaccc aagccatcgg tttggttcac tctttaaacg gccattgtca
     1201 atcaagtgtt acttcaaaaa caaatttcct ggtttgtggt cagtattcta agtcgttgtt
     1261 tgatgattct ctctatacaa aaaaggaaca aaccgcgcgg gacttgattg cgttaggtca
     1321 tgagattacc attttatcag aagtcgaatt ttatgcgtta attagtcaac agttgaaaga
     1381 atggcaacgg tatttataat cgttagtaaa atttacaagg aggaaaattt ttatgaagcg
     1441 aaaatcttat gatcgttggg gcattgaaat aactagtttt aatcgaaata ttgcttttca
     1501 cgtggagtgt gactgtgggg aattagcaaa aagtgtttat caaaaaaatt acttttactg
     1561 tcctaaatgc catcgccgat acggggtaca tggaacatag aaacgaaata gtgcggtaga
     1621 aaagcgaatg aatgtagtat atttctacaa atcattcgct ttctttattt tataaatagt
     1681 tggtcgagag atcccgtttt cttttgcaat ctctgcaact ggaatgcctt gctttaacat
     1741 gtccaccacg gttttaaaaa ctaagcgttt ttgcggatct gttgagttaa tagaatactc
     1801 gattggtcgt cccttatatc ggccggcttt ttgagccaat aatactcctt gccgctgacg
     1861 ttcacgaatt ttctcacgct cgttttgtgc aatataactt agcagtgata aaaacatatc
     1921 gaacatagcg gtatccagga gttcatttcc agtattaaaa tctaaaaact gtgcatctaa
     1981 tatttttaac gctacttttt tctgtttcat aaaagcaact gtatttttta tatcttcata
     2041 atctcttcct aaacgatcta gtgat
//
LOCUS       DACDLM010000169         1995 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.177, whole genome shotgun sequence.
ACCESSION   DACDLM010000169 DACDLM010000000
VERSION     DACDLM010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1995
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.177"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            128..1852
                     /locus_tag="IV356_002945"
     CDS             128..1852
                     /locus_tag="IV356_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HAP9016551.1"
                     /translation="MKKKLLTLFLVMSFSIVLSVYYNTIVFSEQINYTEEQYNIEKEK
                     ALKVGYSEEQFKQIMEIPTNLSNENSETRIVNYTMTSNQTKVINKAMEQIGKPYEWGA
                     SGPNSFDCGGLVKYVYKQAVNIELPMGTTNQEQYGTEVSLNSLKPGDLLFYGNRGATY
                     HVGIYKGNGVMIHAPQPGETVKEVNIQYFYPNFAKRILPDEPDYPYIDYNKMVTVTKA
                     WSIWNDLQFSHEIKKAIIGDNYKIGKVYTNPENNNKYGEILVSNKVYGYINFYAVKEL
                     TSVQINRYLTSKDSGQPTWGNLECTISKGQTTKDKIYFVKGAYNLGDGKYLYSIYKDQ
                     DSSEWLGYLKAHVSLAYTPIEEINKNVTVTKNWSIWNNLQWEKEIEKPQIGSVFSARL
                     KLTNVSNNAVYYKLYKSGKFYGYINAEAVKDLTTTKLNKYVTFSVNNEDFWSSLDVNY
                     SKGKTERGRVFYISISYNTADNQPIYSVYTDETCTEWRGYYKGNNFEDTQITMLENKS
                     VKVTKSGYTVWGDLNFWTKSGISNTGDIYTTDRKFYNFTNNAYYYELKKDGRVYGYIN
                     SEAAVEMN"
BASE COUNT          783 a          242 c          348 g          622 t
ORIGIN      
        1 cagtttgtaa caaacatata ttttttatat tacaatattt caacaaatta aaaaaaatta
       61 tatcttctta aacaatgata atattaaaat gcaagcgctt gtaaaaaata aggagaagag
      121 gtaaaaaatg aagaaaaaac tattaacttt atttcttgtg atgtctttct caatcgtttt
      181 gagtgtgtac tacaatacta ttgttttttc agaacaaata aactacacag aagaacagta
      241 taatatagaa aaagaaaaag ctttaaaagt tggttatagt gaagaacagt ttaagcagat
      301 tatggaaata cctacaaatt tatcaaatga aaatagtgaa acaagaatag taaattatac
      361 tatgacttct aatcaaacca aagtcattaa taaagcaatg gagcaaattg gaaagccata
      421 cgaatgggga gcatcgggac caaattcttt tgactgtggt ggtttagtga aatatgttta
      481 caaacaagct gtaaatattg aactgcctat gggaaccacc aatcaagagc aatacggtac
      541 agaggtaagt ttaaattcac ttaagcctgg tgatttatta ttttacggca atcgaggtgc
      601 aacttatcat gtaggtatat ataaaggtaa cggtgtaatg attcatgcac cgcaacctgg
      661 agaaactgta aaagaggtta acatacaata tttttatcct aactttgcaa aaagaatttt
      721 gcctgatgaa cctgactacc cttatattga ctataataaa atggtaactg ttacaaaagc
      781 ttggtcaata tggaatgatt tacaatttag tcatgaaatt aagaaagcta ttattggaga
      841 taattacaag atagggaagg tttatactaa tccagaaaat aataataaat atggagaaat
      901 attagtaagt aataaagtat atggatacat taatttttat gctgttaaag agttgacctc
      961 tgttcaaata aacagatatt taacttctaa agatagtggt caaccaactt ggggaaatct
     1021 agagtgtact ataagtaaag gacaaactac aaaagataaa atatattttg ttaaaggagc
     1081 atataattta ggggatggaa agtatctata ttctatttat aaagatcagg attcctctga
     1141 atggttaggg tatttaaaag cacatgttag tttagcctat actcctattg aagaaattaa
     1201 taaaaacgta actgttacta aaaattggtc gatttggaat aatctacaat gggaaaagga
     1261 aattgaaaag cctcagattg gttctgtatt ttcagctaga ttaaagttaa ccaatgtatc
     1321 gaataatgct gtctattaca agctttataa atctggaaaa ttttatggtt atatcaatgc
     1381 tgaggctgtc aaagacctta caacaacaaa gcttaataag tatgttacat ttagtgttaa
     1441 taatgaagat ttttggtctt ctttagatgt aaattattca aaaggaaaaa ctgaaagagg
     1501 ccgagtattt tacattagta tttcatataa taccgcagat aaccaaccga tttattcagt
     1561 atatacagat gaaacatgta cggaatggcg agggtattat aagggaaaca actttgaaga
     1621 cactcaaatt actatgcttg agaataaaag cgtgaaagta acaaaaagtg ggtatacagt
     1681 atggggagac ttgaattttt ggactaagtc aggaatatcg aacacaggag atatatacac
     1741 cactgaccga aaattttata attttaccaa caatgcttac tattatgaat tgaaaaaaga
     1801 tgggagggtc tatggctata taaatagtga agcagctgta gagatgaact aaaatattgc
     1861 tgtcccttaa tcttatgggg cagcaatatt tttatattat taatcatttt tctgaagcga
     1921 gggtagaaga attaatcaat agtttttctt gttttgtaat ataatagttt aattaccaaa
     1981 aattatttaa gtaaa
//
LOCUS       DACDLM010000170         1994 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.178, whole genome shotgun sequence.
ACCESSION   DACDLM010000170 DACDLM010000000
VERSION     DACDLM010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1994
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.178"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(63..356)
                     /gene="rpmA"
                     /locus_tag="IV356_002946"
     CDS             complement(63..356)
                     /gene="rpmA"
                     /locus_tag="IV356_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HAP9016552.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            complement(369..713)
                     /locus_tag="IV356_002947"
     CDS             complement(369..713)
                     /locus_tag="IV356_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HAP9016553.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            complement(740..1048)
                     /gene="rplU"
                     /locus_tag="IV356_002948"
     CDS             complement(740..1048)
                     /gene="rplU"
                     /locus_tag="IV356_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HAP9016554.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            1330..1971
                     /locus_tag="IV356_002949"
     CDS             1330..1971
                     /locus_tag="IV356_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAP9016555.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
BASE COUNT          602 a          436 c          351 g          605 t
ORIGIN      
        1 tttataaaca aaaaaggctg tgacaaaagt cttgtcacaa cctctttaat cataagattc
       61 aattaagctt cttgagctac tggataaaca gacacttgtt ttttgttacg gcctttacgt
      121 tcgaaacgta ctacgccatc aacttttgca aataaagtgt cgtctccacc gatacccacg
      181 tttacacctg gatagatttt tgtaccgcgt tgacggtaaa gaattgatcc acctgtaact
      241 gtttgtccat cagcacgttt agcacctaga cgttttgatt ctgagtcacg gccgttagat
      301 gtagaaccgc cacctttttt gtgggcaaat aattgtagat tcatagataa caacatggtc
      361 tgcacctcct atttatcatt aattgtttta atttggatat attctgagtt ttcagcttct
      421 atcgattgta atcctaataa aagattttct aatagaatct cagcaatatt gttttgttct
      481 tgtgtcattc ctgaagtgac ttcggtataa agataaccgc cttcttcttc attcatttca
      541 acaatcggct caaaaccggc taatgaggca atcccgttga cagtgctgat cgctaacgca
      601 gaaacacccg cacaaacgat atcacttcca taaggaccag catcagcatg cccggtcaaa
      661 gtgaatgaaa cgatctgacc tgcgtcattt cgcttaaatg ttcctttgat catatatagg
      721 ccttctttct caaacgctat taagcgttga tcgcgtcgat aaccactttt gtatatggtt
      781 gacgatgacc ttgtttacgg tgtgaatgtt ttttaggttt gtatttgaaa gtaacgactt
      841 tcttttgttt gccgtgtttt tcaacagtac cttcaacagt tgcacctgca acagttggag
      901 cgcctacttt tgtagattct ccgcctacta agataacttc gtcaaaaaca actttttctc
      961 ctgcttcaac gtcaagtttt tcaacataga ttgcttgtcc cacttcaact tttacttgtt
     1021 taccaccagt tttaataatt gcgtacatgc tataaagcac ctccttctga tatacttaga
     1081 ctcgccatcc gaagtgacag catatgctgt gcttattact tgttctgagc ggttgtagct
     1141 gtggagtcca caattacaac agtactagct taccagaaca gcaaccgtta gtcaactaaa
     1201 tttaaaatca aaaagtaaaa caaaaattca agcaatactt ctgcttttct atcctcacag
     1261 ttctaccaaa taaaatagtc gcattgtgtt tcttttattc ttataataaa agaaaaagga
     1321 ggagcataaa tggaataccc aaaagaactg atacaagaag cttctttaag aatgaacggc
     1381 cgtcctgtag aaggatttat cgctgggcaa ggacctcttc atcctaaact gatgctcgtg
     1441 ggagaagccc cagggaaaac agagattgat acgcatgttc cttttagcgg tcaagctgga
     1501 aaagaattga tgcaggcact ttcttcaact ggcttaacac gagaagaggt gtatatcacc
     1561 agtgctgtaa ggagccgccc gtatcgcgtg actcatcgga tcaataaacg gacacaacag
     1621 tcagaaactg tttatccaaa tcggacacct actcgttccg aagtatttgc gcatgcacca
     1681 atattggatt acgaactgat gaaggtccag ccaaaattaa ttgcgacact tggaaacatt
     1741 ggtcttcaac gtttacttgg caaagaatat acggttacca aaaatcatgg tcaactctat
     1801 acagggcctg tcttacaatt aacagaacaa aaggatgcct acgaatggtc agaaaaaaac
     1861 tatcgaattc ttccactttt tcatccagca gctattttct acaatcgctc ccttgtacct
     1921 gttatccatc aagactggca agtactagct tcacttttac agcaatatta aaaagaacag
     1981 acaagaccat aaaa
//
LOCUS       DACDLM010000171         1839 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.179, whole genome shotgun sequence.
ACCESSION   DACDLM010000171 DACDLM010000000
VERSION     DACDLM010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1839
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.179"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            607..1080
                     /locus_tag="IV356_002950"
     CDS             607..1080
                     /locus_tag="IV356_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HAP9016556.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1089..1316
                     /locus_tag="IV356_002951"
     CDS             1089..1316
                     /locus_tag="IV356_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP9016557.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT          597 a          301 c          276 g          665 t
ORIGIN      
        1 ggatttatgg tactttttat tcggcaatcc attttatttt tctacttctt cttaatacct
       61 ctaacacttt tgatttataa actaatccaa tgcatctact tgcgcttatt aagctatttc
      121 agctagatag taccacccca tgcgtcaatg cttgattttc cttttgtata acattgtata
      181 agcaataaag gacaaataag tggtgattac accaaaccat tgaataagaa aaattctgat
      241 acgtaaataa acatgaactt gaaaaaatta atgaatcggt tagctactac gtagttgtct
      301 tttttctcat acagttctgt taacttacac ttctcttcgc tagataataa aaaatcctcc
      361 aactgtattg tccaatataa tcccaggcat ctaaactagc attatagaag agacacacat
      421 agaatctaaa ataactggtt ttaaatgttt cttacaatca aaaaaagctg ttaaatgcac
      481 tccacacctt catactctat cattttttat aaacgatata tttttattgt ttttcgataa
      541 aaaatagttg ttttacaata attattctgc tatattttag ctatcaaaga taaaagaggg
      601 ataaaaatga aatttaaaac attgctatta aaatttgtcg ttttaggtat aagtgccgta
      661 tttattttgt tcggcgtact tttttatact cagatcgcta caagcgaaaa aggattcaat
      721 tttgattggc agaccacatt atttgtttct gtcatttact ttgcccttct cctagggatc
      781 gttattgctt atttcttatt gaaactattg aaaaaaatcg aagataacca agctttttcc
      841 actcaaagct taaacatact aaaaaaaatc gaacgaacca ttttgtttat tggtttcgcc
      901 ttttttggct tacttcctaa atttatgaaa gtagcggatt tagacgatgc tccaggtttg
      961 atgttggtag gaatcgctgt cgtattcatt ccttttgcag tatacacatt aacaagcgtg
     1021 ctggaaaaac tgcttgaaca tgcgatttta cttaagacag atcatgattt gacagtgtga
     1081 ggtgcgacat ggcaattatc gttaatttag atgtagtatt agctcaaaaa aaaatgagtg
     1141 tgactgaatt gagtgagaaa gtgggcatta cgatggcaaa catctctatt ctaaaaaatg
     1201 gaaaagcaaa agccatccgt ttttccactc tcgaaaaaat ctgccaagtt ttggagtgtc
     1261 aaccaggtga tttgttgacc tataaaaatg actcgaatac tataccagaa gaataaaata
     1321 aagtagaaca aacagtaaat aaaaaataat ctgaatgata gatgtgtgag acttttagaa
     1381 gttatttacg tctattattc agatttttta tttcgattga ataccgtttt atctataaat
     1441 aagatatgta ctgactcata caaagggggc cttttcttct ccatgtacta tcacttttcc
     1501 tgatacaact ggtttcctgt tacgttgtag ttggatctgc ttttagtata atactttatt
     1561 cattccacca gactgatagc agtttgagca gtctaaataa tcatgtagta ttacaggcca
     1621 ttctgtttca taccttgaag tgcttaaaac ttcagctaat ggcccattgt gttaactctt
     1681 actccattct tttttagtaa gctcccatat atactgtaaa gccttctata tattatgtca
     1741 tgttgctttt taacatttac tatgtagttt tgataaaatg atttgaataa cagtgatgga
     1801 caattctttt ttatttttaa cattattttg ataataatg
//
LOCUS       DACDLM010000172         1834 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.180, whole genome shotgun sequence.
ACCESSION   DACDLM010000172 DACDLM010000000
VERSION     DACDLM010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1834
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.180"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(162..1667)
                     /locus_tag="IV356_002952"
     CDS             complement(162..1667)
                     /locus_tag="IV356_002952"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar isomerase"
                     /protein_id="HAP9016558.1"
                     /translation="MRTKKAFYNTTTGIIYQLCSIVCGFIIPRLILGYFGSEYNGMIS
                     SITQFLGWISILTAGVGGVTRAALYKPLNKNDNYKISGIINATDNFMKKIALIFLGGL
                     IIFAIGYPFLLKNKFEWFFVFTMVLVLGINTFAQYFFGMTYQNLLEADQRQYIYSTVR
                     ILTTLISTLVTVVLIIMHFDIRIVKLASSLIFAVNPIFLNIYVKKYYSIDTKIAPDNS
                     AISQRWHAFAQEIAVMINNNTDIVVLTIFSNVLEISVYVIYNMVLSGVKQLLQTFTTG
                     IGAAFGSMIAEGIDNSSLNRKLKVFEVLVYNITTILFSVTLVTIVPFVRVYTSNINDV
                     NYIRPVFAIIITIAAMFNCFRIPYQTIVYAAGHFKQTRNGSIVEVILNLSISIILVIK
                     IGLIGVAIGTLVGSIFRTLQYGIYLSRNIIVRSNWLFYTKIVISLLETMIIYIISSIF
                     INISNVSYFGWISYAINIFMLSIAIVCMGSFLFYRKDTISIIKRLIFALKR"
     gene            complement(1669..>1834)
                     /locus_tag="IV356_002953"
     CDS             complement(1669..>1834)
                     /locus_tag="IV356_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012145247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016559.1"
                     /translation="LSNPFPYVRVDFYECNNIPVFGELTFTPASGRSPYMTREADEYM
                     GNLLNLKEME"
BASE COUNT          704 a          300 c          207 g          623 t
ORIGIN      
        1 ttctataagc tatcatttaa atcttaattt agataattta tatagttatt actaaaaaat
       61 ctaatgtaat agaataaaca tttcacgact atctaatcct caaccaaatt aatagtctaa
      121 tagtcgcaat agatattctc aaattaaaaa tactttttat atcatctttt caaagcaaat
      181 attaatctct ttatgattga aatagtatct ttcctataaa ataggaaact acccatgcat
      241 acaatagcaa tagataacat aaatatattt atcgcataac taatccaacc aaaatacgaa
      301 acattactta tatttataaa tattgagctt attatataaa taatcattgt ctctagaaga
      361 gaaataacaa tttttgtata aaataaccaa ttagagcgca ctattatatt tctcgataaa
      421 tatataccat attgtagcgt tctaaatata gaacccacta atgtacctat tgcaacgcct
      481 attagtccta ttttaataac tagaattata gaaatcgaaa gatttagaat aacttcaact
      541 atagaaccat ttcttgtttg tttgaaatgt cctgccgcat atacaatcgt ttgataagga
      601 attcgaaaac aattaaacat agcagcaatt gtaataataa ttgcgaatac cggacgtata
      661 taatttacat catttatgtt tgaagtataa actctaacaa atggtacaat tgtaactaat
      721 gttacagaaa ataaaatagt agttatatta taaacgagta cttcaaaaac tttaagctta
      781 cgatttaagc tactattatc tattccttcc gcaatcatgc ttccaaatgc tgcccctata
      841 cctgtagtaa atgtctgtaa taactgctta actccactta aaaccatgtt ataaattacg
      901 tatacagaaa tttctaatac atttgagaat atagtaagaa cgacaatatc cgtattgtta
      961 tttatcataa ctgcaatttc ttgtgcaaaa gcgtgccacc tttgcgaaat cgctgaatta
     1021 tccggtgcta tttttgtatc tatgctgtaa tatttcttaa cataaatatt caaaaaaata
     1081 ggattaacag caaaaattaa tgaactagct aattttacaa ttcgtatatc aaaatgcatt
     1141 ataattaata caaccgtaac taaagtactg atcagtgttg ttaatattct aacagtagaa
     1201 taaatatatt ggcgttgatc agcttctaat aaattttgat atgtcattcc aaaaaaatat
     1261 tgagcaaaag tattaattcc caaaaccaat accattgtga aaacaaaaaa ccattcaaat
     1321 ttgtttttta agagaaatgg ataaccaata gcaaaaatta taagtccccc caaaaatatg
     1381 agagcaattt ttttcataaa attatcagtt gcgttaatta ttccgcttat tttataatta
     1441 tcatttttat tcaatggttt gtaaagagca gctctagtga ctcctccaac tcctgcagtt
     1501 aaaatactaa tccatcctaa aaattgggtt atagatgaaa tcataccatt atattcggat
     1561 ccaaaatatc ctaaaatgag tcttggaata ataaaaccac atacaataga acataactga
     1621 tatatgattc cagttgtcgt attataaaaa gctttcttcg ttctcatttt attccatttc
     1681 ctttaaattt agcaaattcc ccatatactc atctgcctct ctcgtcatat acggagatct
     1741 tccacttgca ggtgtaaaag ttaactctcc aaaaacggga atattattac attcataaaa
     1801 atctactcta acgtagggga aaggattaga taat
//
LOCUS       DACDLM010000173         1770 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.181, whole genome shotgun sequence.
ACCESSION   DACDLM010000173 DACDLM010000000
VERSION     DACDLM010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1770
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.181"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            197..424
                     /locus_tag="IV356_002954"
     CDS             197..424
                     /locus_tag="IV356_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAP9016560.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            547..873
                     /locus_tag="IV356_002955"
     CDS             547..873
                     /locus_tag="IV356_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAP9016561.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            941..1654
                     /locus_tag="IV356_002956"
     CDS             941..1654
                     /locus_tag="IV356_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAP9016562.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
BASE COUNT          686 a          273 c          373 g          438 t
ORIGIN      
        1 aacaaagtag ttgacacttc cgctacttag tattagtacg aaagtatact tcatgatact
       61 aagtagataa gaagtgaaaa gcggaaccca cgatcgtcaa aatgctaact gctttgctta
      121 caccagataa agggaagagc aatatcgctt attttaggcg tggagaagca agcaaatccc
      181 tacgatcaca aaaaaaatgc tgacccagca gttaagagag ttagaacaag atgaaagtat
      241 ccatcgaaaa gcctataacc aagtcccgcc taaagtagag tactcgctca ccgaagaagg
      301 aaaatcatta agagagattc tagtagcgtt gtctgtttgg gaagaagaac gtatcgaaaa
      361 acaaaaagcc tcaagggaag aagacacgct actgcataca catggtggct acctaaatta
      421 ttgattttct atgacattta ttttaaataa aagaaaacag gagttttttt aaaagcatca
      481 tctatttttt atgtaaaaaa atggtatgat taatcaagta agaagtgatt ggaagaaggc
      541 aagcaaatga atagtatgga aaaagtcaac cagtttagag atgaacgtaa ttggcgacaa
      601 tttcataacg aaaaagattt ggctatctct atttctttgg aagcatctga attgttagaa
      661 ctttttcaat ggaaaacgcc ggaagaagta aaagaaacac aattagaacg aatcaaagaa
      721 gaactggcag atgtattgat ctattcatac atgatggcag acaaccttca cctggatcta
      781 gatgagatca ttgaagaaaa attgatcaaa aataatttga aatatcctgt agaaaaaagc
      841 gcaggtgtac gaaaaaaata cacagagttg tagaaatgtg tcattcggct gttggaaaga
      901 gcaaaagaaa aacagtaaaa tgagtctgga gggagagaaa atgaaaaaaa aaggaaaagc
      961 aaaaagatgg ctagtcaata tcctcttgtt cctcttgtta ttagtaggac tagctttgat
     1021 tttcaatgaa cagatcaagg attattttgt cagagagaca ggagataaat atgctatagc
     1081 gaatgtaaca aaagaagatc tgaaaaagaa taacgataaa gatgtcagtt ttgactttga
     1141 tgcggtagaa ccaatgacga cagaaggggt catgaggtcg caaatgagag gaacagatct
     1201 accagtgatt gctagtatcg cagtcccttc agtttcaatc aatttaccgg ttttcaaagg
     1261 cttggataat acgtcactac tttacggagc aggaacatta tctccagatc aagaaatggg
     1321 aaaaggaaat tatgccttag caagccatcg tgcaacgaac cctgaattgc tgtttacacc
     1381 gctagaaaat ttagagatgg gtgccaagat ctatttgaca gatttagaaa atgtgtatac
     1441 atacaaaaca ttttttaaag aaaaagttgc tcctacagat acccaattac tgaatgaagt
     1501 cgagggaaaa gaaattgtca cactaattac ttgtggcgac atggacgccg tcacgcgact
     1561 agttgtacaa ggagaactgg aaagtgttac atcgataaaa gatgcgacag atgatatgag
     1621 atctgctttc aatctagaga caaaaacatt ttaggatact gggacataag tcgttacaga
     1681 ttaaaaacag ccaaaggata tgaatcgata aggaaaaacc aatttgctga aaaaaagaga
     1741 aacgcaaaga ggtgcatctc tgatttggtt
//
LOCUS       DACDLM010000174         1652 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.182, whole genome shotgun sequence.
ACCESSION   DACDLM010000174 DACDLM010000000
VERSION     DACDLM010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1652
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.182"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            96..506
                     /locus_tag="IV356_002957"
     CDS             96..506
                     /locus_tag="IV356_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAP9016563.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     TLAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            520..876
                     /locus_tag="IV356_002958"
     CDS             520..876
                     /locus_tag="IV356_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP9016564.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVEKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            complement(1484..1627)
                     /locus_tag="IV356_002959"
     CDS             complement(1484..1627)
                     /locus_tag="IV356_002959"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016565.1"
                     /translation="MEKEAFDLHVLGTPPAFVLSQDQTLIKSSNNLAIVKLNLFASIL
                     LAC"
     gene            1546..>1652
                     /locus_tag="IV356_002960"
     rRNA            1546..>1652
                     /locus_tag="IV356_002960"
                     /product="16S ribosomal RNA"
BASE COUNT          591 a          256 c          311 g          494 t
ORIGIN      
        1 ttattttgat ttttttttat attttattag ctaataattg gtattttaaa agaaattact
       61 gtagaattgg attataatta aaaaggagtg agaaaatgat aaaagtatat acttcgccta
      121 gctgtacttc ctgtagaaaa gcaagagcat ggttgcaagc gaatcaactt gaatttgaag
      181 agaagaatat ttttgccgaa ccgttaacag aaagtgagat caaaaagacc ttggcagcga
      241 ctgaaggagg agttcaagat attatttcca ctcggtcgaa aatttacgaa aagctgggca
      301 tagattttaa cgaattaact ttaaagcaaa tgatcgtctt attcaaagaa tatccttcat
      361 tattgagacg acctattttg attgatgaaa aaagaatact aatcggattt aatgaagatg
      421 agatccggtc atttgtccct cgtgaaattc gatgtgttgc cagaaatctg atctatttac
      481 aaaacaataa catcttaaat tcatagggag ggagccttcg tggaagtgaa agtctatgga
      541 tcagcgcact gtgtaacaag tctgaaggcg aaacaatggt tagaacacca tcaattgcct
      601 tatcaatttg ttgacttaga agaacgcgat ctaagtacag aagaagcaga agaattatgc
      661 agttttgaag aagtgcaagc agaacagcta tttgcgactt ggtctgaggc ttttcacaac
      721 attgcgattg acctttcctg tgtagaaaaa aaacaactga tttttttatg cacacaacat
      781 accaacctcc tcagacgtcc tttgattatt atcgatgaag ttctatttat tggatacaat
      841 gagcagttga tggaacagct tatcttaaat aaatagactt taactgtttt aatcaagtca
      901 ctgagcattc catacagttg taacagtcga acacttagca tcaagcgtgt tatgtgttct
      961 ttttttgact ttatttttct actatagaga catgctcaat ttatgtggtc aaaattcaaa
     1021 tctaggtggg gatatagagt taaaaatata ttgacatgtg taaatttaca tgatatattc
     1081 atttctgttg ttttaagtag caaagcaata aaatagtatt ttaaaaaaca tataaaatag
     1141 ttgttgacat gttagaaatg acatgataag ataactgagt cgttaaaaaa ggaccgcttg
     1201 cgaagcttga ttctatcgaa aaaacttcaa aaaagttctt gacaaataac aaacgacaag
     1261 ttatgataaa tgagttgctg taagatttcg aaaaacgaaa tcaaaaaaac ttttaaaaaa
     1321 gagttgacaa ttacttgtct ctctgatatg atataaaagt tgctgcggca gccaaaaacg
     1381 aatcgggaaa cactcctgat gaagtagacc tttgaaaaat gaacaaagta agacaaacca
     1441 aatgtgtagg gcgtcttgat tcaattcaag acaacaaaca tttttaacaa gcaagcaata
     1501 tgctagcaaa caaattgagc ttaacaatcg caaggttgtt cgaacttttt atgagagttt
     1561 gatcctggct caggacgaac gctggcggcg tgcctaatac atgcaagtcg aacgcttctt
     1621 tttccaccgg agcttgctcc accggaaaaa ga
//
LOCUS       DACDLM010000175         1632 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.183, whole genome shotgun sequence.
ACCESSION   DACDLM010000175 DACDLM010000000
VERSION     DACDLM010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1632
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.183"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            244..939
                     /locus_tag="IV356_002961"
     CDS             244..939
                     /locus_tag="IV356_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016566.1"
                     /translation="MRSSKYTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVL
                     KGIEIGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDDEVKDMDPAIVIPQYFA
                     QLSEALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPILDQVIKNKLAFELNAKS
                     AYLYDNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFDDLFALLKAKGVTELAI
                     YQKRKRIMVPLPV"
     gene            complement(976..1473)
                     /locus_tag="IV356_002962"
     CDS             complement(976..1473)
                     /locus_tag="IV356_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP9016567.1"
                     /translation="MNNQIALAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
     gene            complement(1529..>1632)
                     /locus_tag="IV356_002963"
     CDS             complement(1529..>1632)
                     /locus_tag="IV356_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAP9016568.1"
                     /translation="LESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT          519 a          294 c          257 g          562 t
ORIGIN      
        1 cttccttttt tgtatggatt ttttcattta cacaaaatat tttacactct ctaataatta
       61 cacacacaca attttttaag gtcttaaaac catcatatat gcaaaagaag ctaaccttta
      121 ttactaaatt agacccgtgg tgctagttaa ttttttccta gaggaaaatg tctaaacatg
      181 ttggtaaatc aacaaaaaaa cgcatatagt agtctcaaaa ctcccaagaa atgaggacta
      241 catatgcgtt catcaaaata tactgaacat tttgacttag ccaatcctgt tactaaagtc
      301 gatgatatcc ccgattatga aatgtacagt caaacaatcg atagcttaaa taagcgtttt
      361 ggcaatcgtg ttttaaaagg catagaaatc ggttacatcg cttctgaaaa ggatcggatc
      421 atcgactatt tagccgataa agattacgat ttaaaattac tcagtgtgca tcataatggt
      481 caatttgatt atttagatga cgaagtcaaa gatatggatc ctgctattgt gattcctcag
      541 tattttgcac aactttcaga agcactagtt gttatagaag cagatgtctt tgctcatttt
      601 gactatggtt ttcgggtatt tggtctatcc gttgctgaat ttaaacaata tgaagcgcag
      661 tttttaccga ttctagatca agtaatcaaa aataaattgg cattcgaatt aaatgctaag
      721 agcgcttact tgtatgacaa tttagcgtta tatgaatatg tcatcgattt atatctttca
      781 cgtggtggta ccttgtttag tgttggatca gatgggcatt accttgaaca tttccgtttc
      841 catttcgatg atctttttgc tctgttaaaa gcaaaaggtg tgacggaatt agcgatttat
      901 caaaaaagaa agcgaattat ggttccatta ccagtctaaa aaaacgtcct cagcatcaaa
      961 agtgaggacg tttttttaga tttctttttc taaaatcgga caaatacgat cttgttttcc
     1021 taaaggaaaa tgtttgatcc cgattttttt aaatccatga cgttcataaa aacgaatacc
     1081 tgcatgattt ttttcataaa cagtcaaacg taaataacgt ttttgtttcg ttttagcata
     1141 acgattcgct tcatcgagta accgttgccc taaccctttg ttttgataat ctttgagcag
     1201 atagagccgt tgaatctcta tagcatcttt ttcatcattg actttcatat aaccaatgag
     1261 tatttgatga tccttaatac caataaattt actggttgac tgtgccaatt ctactgccaa
     1321 tatttcagtt gtcaattgtg tctgtaaata tccttgcata tcaagtggat ctgcgccatc
     1381 gataaacgat tcataaaaac tgacaacact tacaacttgt aaagcatcta gatcatcata
     1441 atctaaatac gctagtgcga tttgattgtt catctaactc ctccttttga catagtatac
     1501 tataaatcac ccgtggtgct agttaatttt aatatcctaa agaatatctc aaagttcctt
     1561 caaaacgtcg ttgtgctcga cttaatagaa cactgtaagc cagtaatatg ctttcaaatc
     1621 tactctctag cc
//
LOCUS       DACDLM010000176         1573 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.184, whole genome shotgun sequence.
ACCESSION   DACDLM010000176 DACDLM010000000
VERSION     DACDLM010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1573
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.184"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..500)
                     /locus_tag="IV356_002964"
     CDS             complement(<1..500)
                     /locus_tag="IV356_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HAP9016569.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLAIFGHKLGSPVDNYRSGTIAEIDY
                     FYKNSKGEVGVFFLDEPVPQVLAEEYIEVKKYRDSLEDKGFYGTYSKDNIRRFLTKKV
                     NYLIEKA"
     gene            complement(659..925)
                     /locus_tag="IV356_002965"
     CDS             complement(659..925)
                     /locus_tag="IV356_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP9016570.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            complement(915..1271)
                     /locus_tag="IV356_002966"
     CDS             complement(915..1271)
                     /locus_tag="IV356_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAP9016571.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
     gene            1406..1513
                     /locus_tag="IV356_002967"
                     /pseudo
     CDS             1406..1513
                     /locus_tag="IV356_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
BASE COUNT          445 a          302 c          214 g          612 t
ORIGIN      
        1 gctttctcaa ttaaataatt cacttttttt gtgagaaacc ttctgatatt gtctttgcta
       61 tatgttccat aaaaaccctt atcttctaaa gagtccctgt acttcttaac ttctatatac
      121 tcttcagcca aaacttgtgg aactggttca tctaagaaaa aaacccctac ctcgcctttg
      181 ctatttttat aaaagtaatc aatttctgct atagttcccg atctataatt atcaactgga
      241 gaacccaact tatggccaaa aatcgctaat aatatatcac tattttctac aatttgttta
      301 ttaataacac tttgcccaga gctattattt atataagtag gaatcgcatt cgtttcccat
      361 cgaattggca tcaaaattac ttttgtatta tctgtatttt ctatattcca tctatatatg
      421 gtttcttcta cttcattcct ctttgctgct atatcacctg gtgatgctat aaatactttt
      481 attagattta tggttttcat ttattgtacc tttctcttta tgtctcttta aagtaatttt
      541 tgtataaaat ttattgactt ttacactata ggacaacttt tatctattta gtacaaaaag
      601 gcccactaaa ctaattgatt agttaggagc ctattacagg tatattttca actcgctttt
      661 aagcaaattc tactaccagc tttttgccta atgccctagc gatatcatca agtttatcga
      721 aagatacgtt atcccctctc tcaattcgag caatagtaga ttgagttgta tgtgcttttt
      781 gtgcaagctc cgcttgagtt aggcctgctt cctcccgtgc atgataaaga gcaaccgcag
      841 tttcgagttt tcttccttca cggtcatatg cttctgcaaa atctttgtct ttttgctttt
      901 cttcaatcaa ttttttaatc atcatttgtg aaccactcct ctctaagttc ttttgcatgt
      961 ttaagttcac ttattggtgt tttctccgtt tttttagtaa atccatgggt aatgacatac
     1021 cttccattga ccacatggaa atagatagct ctttggatgt ttgatcctac cttacttctt
     1081 aattcgtaca aattagtgtc taattttttc acccatttca accgttgagc tactagcatc
     1141 ccattctttt ctgtttcttc tattgtacgt aaaagcttcg cactatcttt ttttggtaat
     1201 gtttccaacc attctaaaaa ttcatcatga ccattaggtc ttttaaatgt ttcaaaagat
     1261 attttttcca tacccaatta tatcatatat tgattttata ttatagtata taacataaaa
     1321 attcgaatta tggttctgtt gcaaagtttt aaatctacta tcaaataagg tagaataata
     1381 gaaaaagata gcaggaggaa tgacgatgaa tcattttaaa ggaaagcaat ttcagcagga
     1441 tgtgattatt gtagccgtgg gctactatct tcgttataac cttagctatc gtgaagttca
     1501 agaaatctgg ttctgttgcg aagtttgaaa atcaaacgcg ccctctctga actccaaata
     1561 tcttaggctg tta
//
LOCUS       DACDLM010000177         1563 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.185, whole genome shotgun sequence.
ACCESSION   DACDLM010000177 DACDLM010000000
VERSION     DACDLM010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1563
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.185"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(1..120)
                     /locus_tag="IV356_002968"
                     /pseudo
     CDS             complement(1..120)
                     /locus_tag="IV356_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177601.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
     gene            233..1423
                     /locus_tag="IV356_002969"
     CDS             233..1423
                     /locus_tag="IV356_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP9016572.1"
                     /translation="MNYFTTSLMKNLFSNDNNLPAFEQAVTELFRSELEKSLNEILAY
                     ELTDFLDYEPYARTNNENSRNGSYQRKFDTKYGTITLNIPRDRMGEFFTSLLPKYRRR
                     DLFTETTILDLFEEGMSHSEICSMIQKLCGARYSKQTISNITDKALECVDSFKNRILN
                     KEYAVVYLDGTSMPLRRDTVSREMVHIALGITVEGTKEILGYMIAPNESAEIWEELLK
                     DLKSRGVERISLFCTDGLSGMENVIQDIFPGSKIQRCLVHIQRNICAKVRVSDRKEVA
                     NEFKEVYRSKSKEEALTSLKKFIDRWKHKYPSMVKSLSNNDYLFTFYDYPESVRHTIY
                     STNLIEGNNKQLKRSFKKKEQFPTEKSEEKYLVIQFNRYNEKNMNHVHRGFGQTTRED
                     WFKS"
BASE COUNT          596 a          248 c          270 g          449 t
ORIGIN      
        1 ttttgcttta aattttgagt catcatttat aagcgaacgt aagagataat agacacctaa
       61 aaatagaaag aaaaataaag gtaatacacg tagtaaaaca aatggagttt caaaaataaa
      121 tggatagcat aaaatatctt gtgtaaattc gtttttctag aaatgtagaa aaaaaggtat
      181 atccttagta aaattagttc gaccaaaaac aatttacgaa aggaatatac ccatgaacta
      241 ttttactaca tctttaatga aaaacctatt ttctaatgac aacaatcttc cagcttttga
      301 acaggctgta accgaactgt ttcgttcaga gttggagaaa tctctcaatg aaatactcgc
      361 atatgagttg acggattttc ttgattatga accatacgct agaaccaata acgaaaattc
      421 tagaaatggt tcctatcaaa gaaagtttga tacaaaatat ggaactatta cactcaatat
      481 tccaagagat agaatgggag aatttttcac ttctcttctg cctaaataca gaagacgaga
      541 tctatttacc gaaacaacga ttttggattt atttgaagaa ggaatgagcc attcagaaat
      601 ttgttccatg atccaaaaat tatgtggagc tcgctattct aaacagacca tatctaatat
      661 tacggacaaa gctctggaat gtgtagattc cttcaaaaac agaatattga acaaagagta
      721 tgccgttgta tatcttgatg gaacatccat gcctttacgc cgtgatactg tatccaggga
      781 aatggtccat atagcactag gaatcacagt agaaggtaca aaagaaattc ttggctatat
      841 gattgcacca aacgagtccg ctgagatatg ggaagaactt ctgaaagacc ttaaatcaag
      901 aggggttgaa cgtatttctt tattttgtac agacggattg tctgggatgg aaaatgtaat
      961 acaggacatt ttcccgggct ctaaaattca aagatgcctg gtccatattc aaagaaatat
     1021 atgtgcaaaa gtaagagtca gtgacagaaa agaagtggcc aatgaattta aagaggtata
     1081 tcggtccaaa tcaaaagaag aagctttaac ttctctaaag aaattcatcg ataggtggaa
     1141 acacaaatat ccatcaatgg tgaaaagtct cagcaacaat gactatctgt ttacattcta
     1201 tgattatcca gaaagtgtta ggcatacgat ttattcaaca aatctgattg aaggaaacaa
     1261 taaacaatta aaacgaagtt tcaaaaagaa agaacaattt ccaacggaaa aatctgaaga
     1321 gaaatacctt gtgattcagt tcaatcgtta caacgagaaa aacatgaatc acgtacatag
     1381 aggttttgga caaacaacca gagaagattg gttcaagagc taatctgctt taccaaggat
     1441 atacttttac acataattct tgacgctccc ttttatttag tgccacttct taataatccc
     1501 attgttatta tcaaataaaa aatacaatat atggttttga ataatttttt gaaagaaggc
     1561 ttc
//
LOCUS       DACDLM010000178         1538 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.186, whole genome shotgun sequence.
ACCESSION   DACDLM010000178 DACDLM010000000
VERSION     DACDLM010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1538
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.186"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(742..1083)
                     /locus_tag="IV356_002970"
     CDS             complement(742..1083)
                     /locus_tag="IV356_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAP9016573.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(1083..1313)
                     /locus_tag="IV356_002971"
     CDS             complement(1083..1313)
                     /locus_tag="IV356_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAP9016574.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            complement(1367..>1538)
                     /locus_tag="IV356_002972"
     CDS             complement(1367..>1538)
                     /locus_tag="IV356_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAP9016575.1"
                     /translation="VETVFSSLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQR
                     RFGGTLRYSLGY"
BASE COUNT          478 a          264 c          225 g          571 t
ORIGIN      
        1 tgtattgata gtgtacctaa aagctctact gacataagat cgtgtaatcg gtaaagtaat
       61 tttattaatt atacgggatg taatcaatta gagaataaac taatcataaa aggtactttt
      121 acattcataa ttgtcgcttt gagattctac tttggttcac tatctgaccc aattgcacat
      181 tttcgatcat tacaagtatt ggtgtcgtta gaacaactaa ataaaaacta gcggtagatt
      241 tttcagaatc tatgctaatt tctgtatgga tgttccagtg atggcaaatt tctcttttca
      301 ttgtttttct tgtcgcatga tatgcctttt tgtgttattc agttaaacta tagaaattct
      361 ttcctagaca gatcttgatc ccaaatttta cgtttttgag catcgatata gtttaaaatg
      421 acattactca tatctaaaga gtttagattt tttaggacta aaactgtcag ttgttctttt
      481 tcttctttct gttaaagtat tgtcgcgact tttcgtatac gttaagatat gtcgtgaaaa
      541 aacaagtttt gtgacacaaa aaaacgaatg acttgaggaa atcacctcaa tcattcgttt
      601 aaaatgctat atattcttta gtttaagata cggaaattaa tgccatcgac cacactagta
      661 gaatgaacga catttacttg gccttttttt aatttcgtta tgtttagcat ataaaaatat
      721 tatagagttt acttacaatg cttaaaacat atactgtata atctgatcaa ttttagccat
      781 gtcttgcaat ggtaagtttt ctattttttt gagttttcgt tccttaaaat caagagattt
      841 taattgtgta ataattactt gtccttttat atctagctct tcaggtaatg agtaacgtgt
      901 cggtaaattc tttatagtgg aagtaattgg acatatgacc gaaaacattg ttttacggtt
      961 aaattcataa cgagagacga ctagtcctgg tcgtcttttt tgaatttctt ttcctacgga
     1021 gggatcaaaa tcaatccata caatatcacc ttttttagga atataaattc tttcttctga
     1081 cactataaaa tttctctccc ttcaggagtt aaatcttccc attcgtcttt ctcataatac
     1141 tcggcctctt ccccaccact aaatggatct tcaatttttg gaactaacgt aattgttcca
     1201 tcatcagaat acacaacgat atattcttgg ttttctgaag gtttctttcc gttatcagaa
     1261 ggtaaagtta ccactacaga acttccttgt aatctagatt ttgtaacaag cattatcatc
     1321 actcccttaa taaaagtata ctatataccc gtggtgctag ttaattttaa tatcctaaag
     1381 aatatctcaa agttcctcca aaacgtcgtt gtgctcgact taatagaaca ctgtaagcca
     1441 gtaatatgct ttcaaatcta ctctctagcc ctttaacaga acgtgagttg aaattttgac
     1501 aacctaattt ttctaaggaa gaaaaaacag tctcaact
//
LOCUS       DACDLM010000179         1482 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.187, whole genome shotgun sequence.
ACCESSION   DACDLM010000179 DACDLM010000000
VERSION     DACDLM010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1482
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.187"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(137..427)
                     /locus_tag="IV356_002973"
     CDS             complement(137..427)
                     /locus_tag="IV356_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016576.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(545..805)
                     /locus_tag="IV356_002974"
     CDS             complement(545..805)
                     /locus_tag="IV356_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016577.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(942..1355)
                     /locus_tag="IV356_002975"
     CDS             complement(942..1355)
                     /locus_tag="IV356_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HAP9016578.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
BASE COUNT          544 a          244 c          219 g          475 t
ORIGIN      
        1 ttgttactat gaataacata ataagaaagt aaagtggatt gatttgagat ctttttatac
       61 ttcaaaaaag ataacaccca actttcaaaa atatgttttg gaagttggga caaacgagtt
      121 aatacatttt aatacattat tttttattca aaaaaaatag cacaatggca aagatcgtaa
      181 gagagatcat aagccccaat gaatgactaa aaagaaaagc agaatcacat gccatatcat
      241 cccatatttc ttcaagaaaa taaataagcg ggaaaaaggg aaggaatagt agaacatcga
      301 tccagcacca tttttttctt cttttgaaat aacataaaac aataaacatg aacgtgcagg
      361 gaagtaaaaa caaagcttta ctcataacta acaaaatacc agctcctttt atttttttct
      421 cccccacatt caaagagtaa caatggtatg tacttaataa tagaaaaatg gatcaacttg
      481 tatgaataac agctgaaaag atctgcacca aataaaaaac ttccagccaa aactgactgg
      541 aagtttattt ttttctgaaa tattctaaca caaatatgaa aaagatggcc gaagctaata
      601 agccgatttc gtagcaaaac aatgagatac cagagtcgta ataataaaat cctctaatct
      661 tatggataaa atagatcatc ggacaagcag ataagagtaa gtatttgtta ggccttttga
      721 ataagtaaaa gaaagcactg gtcattatga taaatggtat ccaaaacaaa agtttactta
      781 agacaatcaa atgatcaact cccatatttt ttaccaagag agatcataac atctttatcg
      841 taaaaacaaa atattttttt gctcattttg aaaatttaaa catactcgtt cttatccaaa
      901 tatataaaaa tcgcccctca ttcatcgaga ggcgataagt tctaatttaa ctcaattttt
      961 tttgtttctt ttggctgata agctgtttta ggtaatacca atttcagcac accgttttta
     1021 aaggttccag tgattttttc ttcatcaaca ttaggaagat agaatgaacg tttgtaagag
     1081 accgaatgtc tttctttccg tacatagttg ccatcttctt tatcttctgt atgggactca
     1141 tgattggcgg agatcgtcaa agtattatct gaatattcaa ctgtcgtgtc ttctttgtca
     1201 cagccaggca tatcagcagt tagtttgtat tctttttcat tttcgactaa atctactttt
     1261 ggataacttg aaacacctaa aaaatcattg aatgctggac taaacacgtc attgaaatca
     1321 gggaacatgt cgcgaatgct aggtacattt gccatttttg atcatccttt caataagtat
     1381 tttttattta tccctattta cgtaataact ctattttgaa aaaaatgcaa gtataatggt
     1441 tagctttgtg aatatttcat ctaatacgat acaaaggcta tc
//
LOCUS       DACDLM010000180         1464 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.188, whole genome shotgun sequence.
ACCESSION   DACDLM010000180 DACDLM010000000
VERSION     DACDLM010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1464
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.188"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            261..1430
                     /locus_tag="IV356_002976"
     CDS             261..1430
                     /locus_tag="IV356_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP9016579.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
BASE COUNT          535 a          209 c          238 g          482 t
ORIGIN      
        1 atttaaaggt aataagttat tcttttatta ctatgtttgg gttttatagc aaagaaagtt
       61 taataagagt ttggacctag caaacaatat taatgaggtc attaaatctt attatcttta
      121 gtgatataac gaaatatcta cacagacaaa atgatagcgt aaaatatttt gtgtaaatag
      181 atatttaggg tagaaaaaaa gaaagtccat tctgtaaaat taaagttacc acaaccgaaa
      241 ttttatagga ggactttctc atgcccaatt ttactacaga aattatggaa acactaatca
      301 ataaaggtga tttagatgaa ttatttcgat gtcatttaga attagctgtt aattcattat
      361 tgcaggctga attaacagct tttcttgatt atgaaaaata tgatcgtgct gggttcaatt
      421 caggtaattc ccgtaatggg aattattcac gttcattcag aacagagtat ggagaattaa
      481 atttggtaat tcctagagat agaaatggta agttttctca acaaacttta cctgcttata
      541 aaagaaccaa tgactcttta gaaaccacta ttattcagct atttcaaaaa ggaattacta
      601 tgtctgaaat ctctgaattg attgaaaaaa tgtacgggca tcactatacg ccacaaacca
      661 tttcaaatat gactaaaata gtttctgaag atattattgc ctttaaagaa aggtccttag
      721 aatccagata ctctgtcatt tttatggatg ctactcacat tcctttaaaa agacaaactg
      781 tttcaaaaga agcagtttat attgtaattg gcattcgatt agatggaacc aaagaggttc
      841 ttgggtttag tcttgctcca actgaatctg cttatgtttg gaaagagatt cttcaagacc
      901 taaaagaccg tggtttaaaa gaggttttat tagtcgtaac tgatggttta agtggcatta
      961 acgatagtat tcatagtgtt tatccaaatg ctcaatttca acaatgttgt gtccatatat
     1021 ctagaaatat cgctcataag gttcgtgtta gtgatcgaca agaaatctgt agcgatttca
     1081 aattagttta tcaagcaagt tcaaaagaag aagcaaataa tcaaataagg tttatgatag
     1141 ataaatggaa aaagcagtat ccacgagtgg ttaaattgct catgaatcct gctatattaa
     1201 ccttttataa tttccctccg tcaatcagaa gaactattta ttcaactaat ttgattgaag
     1261 gttttaacaa acaattaaag aaatatacca aaagaaaaga gcaatttcct aatgaagaat
     1321 ctctggagag atttctagta tctcaattca acaactataa tcaaaagttt ctatgccgag
     1381 ttcataaagg ttttaaagaa atacatgata cattagaatc aatgttttaa cttgatcaac
     1441 agaatgggct tttccattta caca
//
LOCUS       DACDLM010000181         1424 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.189, whole genome shotgun sequence.
ACCESSION   DACDLM010000181 DACDLM010000000
VERSION     DACDLM010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.189"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..537
                     /locus_tag="IV356_002977"
     CDS             <1..537
                     /locus_tag="IV356_002977"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016580.1"
                     /translation="VMAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNG
                     QPMNDKRNGHSWFRQQERIENKVHSLREEIKQQEKQVEKLERQEEIKEMGYNKYGGLD
                     MTIDNIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKERSEKGKENLLPEVQA
                     IIDSGRVTQWKKIRPFIF"
     gene            564..>1424
                     /locus_tag="IV356_002978"
     CDS             564..>1424
                     /locus_tag="IV356_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016581.1"
                     /translation="MNENGEFEESKKYQATSEEEKAAVRELLEEAVPTDFLKEKENDH
                     FYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYYKFYFEEVKNGEVV
                     DQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKEQMQSKETKTKQKG
                     YQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFPERSFRNQLLIEEQ
                     FPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGFVREIEATPEDKKR
                     IESGQIEVIKK"
BASE COUNT          590 a          223 c          317 g          294 t
ORIGIN      
        1 gtcatggcag aagaaaaaga accactagac aatagtcgtt tgggaaaatc caaaagaaaa
       61 ttagtacgat tgcaaaatga attaaacgaa caaattgaaa agatgtttga acaccagaga
      121 aagaccaacg gtcaaccaat gaacgataag agaaatgggc attcttggtt taggcaacaa
      181 gagcgaatcg aaaataaagt gcatagtctg agagaagaga tcaagcaaca agaaaaacaa
      241 gtagaaaaac ttgaaagaca agaagagata aaggaaatgg gctataacaa gtacggcgga
      301 ctggatatga cgatcgataa tattccaaga atcaaagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcga ctttttcagc cgctacgatc cgaaaatacc aacggaaatt ggaaacatta
      421 gaacagctga aagaaagatc ggaaaaagga aaagaaaacc ttcttcctga agtacaagca
      481 atcattgaca gcggacgagt gacgcaatgg aaaaaaatcc gaccatttat tttctgaaag
      541 gctatcgaaa agtcgcttta gaactgaatg aaaacgggga atttgaggaa tctaaaaaat
      601 accaagccac gtcggaagag gaaaaagcag ctgttcgtga attacttgaa gaggctgtac
      661 caactgattt tttgaaggag aaagaaaacg atcattttta tcgagtagaa ttcaacgaaa
      721 atgatccaga aaaaggattg aaaagttatg gtggggagat cgtaacattc gaattgatcg
      781 atcaactcaa aacgttggat aaccaatacg ccgcagaagc aggttattat aaattctatt
      841 ttgaagaagt gaagaacgga gaagtagtcg atcagatccg aatggatcta ggggatggcg
      901 tcaacagtaa tcaacccatc tatttagagt tagcaaaatt gtgcgaacaa gtacctgaga
      961 aggaacaaaa acaatcggtc aaaaatgaac ctgtttcgaa agaacaaatg cagtcgaaag
     1021 aaacaaaaac aaaacaaaag ggctatcaaa aacgaacggc agaagagatt aaacaagaag
     1081 ttaaatccct ttcgcaacag gcactggatg cggtgaaaaa gcatactcat tctcctgaag
     1141 acgtcaaaga acttttgaac tttatgtctc gttttccaga acgatccttt agaaatcaat
     1201 tattgattga ggaacaattt ccaggtgcaa cggcttgttt aggtcgtgcc gcgttgaaaa
     1261 aagaaggaat ctatatcaaa aaaggggaac aagggaacaa gatctttgtc agaaaaacgg
     1321 tcaaaggatt ttatgagaaa ggacgtggct ttgttcgaga aatagaagct acaccagaag
     1381 ataaaaaacg aatcgaaagt ggtcaaatcg aagtgatcaa aaaa
//
LOCUS       DACDLM010000182         1424 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.190, whole genome shotgun sequence.
ACCESSION   DACDLM010000182 DACDLM010000000
VERSION     DACDLM010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.190"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(150..1337)
                     /locus_tag="IV356_002979"
     CDS             complement(150..1337)
                     /locus_tag="IV356_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HAP9016582.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DACDLM010000183         1419 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.191, whole genome shotgun sequence.
ACCESSION   DACDLM010000183 DACDLM010000000
VERSION     DACDLM010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1419
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.191"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(98..>1419)
                     /locus_tag="IV356_002980"
     CDS             complement(98..>1419)
                     /locus_tag="IV356_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HAP9016583.1"
                     /translation="GLGIYGYVFSISQFLMTVIAVGMNPFRIRNIAKSRKDKKALSLQ
                     FWNIYFLQFLIGLSVSFLYIAYIYFFDVKYKNLYLIQLIFIAGLTLDISWFFQGIEEF
                     SKVVIRNTVIKLSSVLLIILFVSTKDDLWIYVFITSITNFLGSLVFWLSIHGKVGKPL
                     FNSNVFKQLWKPAFIILTPQLFMQVYTTLDKTIVGYFVDPTALSYYDQSQKIARIILA
                     VLTSITIVMLPKISKAQAEGKSENILVYTKKSFDYTIIIALILFSVVFINTKEFVPWF
                     FGENFKPMTINMLISCLIIVVSPIGGVFANQFAIAIEKDKEYAYPMIIGAIVSIIGNV
                     AFVPTYGAVAATIVLVVVELLVFFFRVFFVRKEIKISYFFGKNVVLFFIVNLTLTTSA
                     YYFLPQLFSSSFLDMAIKSIMIFIIYLPFVYFLFPDIRNEVRKIIRK"
BASE COUNT          566 a          229 c          186 g          438 t
ORIGIN      
        1 ctatgcatta aaagctagta aatcttacta actttgttga tcataaatga ccttatcagc
       61 ccgatttgac aaagaactac ttttttacaa cattatttta ttttcgaata atctttctta
      121 cttcatttcg tatatctgga aaaagaaaat aaacaaacgg aagataaata atgaaaatca
      181 ttattgattt aattgccata tctaaaaatg aagaagagaa taattgtgga agaaagtaat
      241 aggccgaagt agtcaaagta agattgacta taaaaaataa gacaacgttc ttcccaaaga
      301 aataggatat ttttatttct tttcgtacaa aaaatactct aaagaaaaag actaataatt
      361 ctactaccac gagtacgatt gtagccgcta cagcgccata agtaggcaca aaagctacat
      421 ttccaataat acttacaatc gcaccaatga tcattggata agcatactcc ttatcttttt
      481 ctatagcaat tgcaaattgg ttagcaaaaa ctccaccaat tggactaaca actataatta
      541 gacaagaaat aagcatgttt attgtcatcg gtttgaaatt ctccccaaaa aaccatggaa
      601 caaattcttt tgtattgata aacaccacac taaaaagaat taatgcaata ataatcgtgt
      661 aatcaaaaga tttttttgtg taaactaaaa tattttctga ttttccctct gcctgtgctt
      721 tagatatttt aggcaacata acaatagtaa ttgatgttaa gactgccaat ataatacgag
      781 caattttttg agactgatca taataagata atgctgttgg atccacaaaa tacccaacta
      841 tcgttttgtc taaagttgtg tacacttgca taaacaactg aggagtcaaa ataataaaag
      901 ctggtttcca caactgttta aaaacattag agttaaagag tggtttacct acttttccgt
      961 ggatactcaa ccagaaaact aaacttccta aaaagttagt aattgaagta atgaacacat
     1021 aaatccacaa atcatcttta gttgaaacaa aaaggattat taacaatacc gatgataatt
     1081 tgataactgt atttctaata accactttcg aaaattcttc aattccttga aaaaaccaag
     1141 aaatatctaa tgttagccct gcaataaata tcaattgaat taagtataaa tttttatact
     1201 ttacatcaaa aaaataaata taggctatat agagaaagga aacactcaag cctattaaaa
     1261 attgaagaaa gtaaatattc cagaattgta aagatagtgc ttttttatct ttccttgatt
     1321 tagcgatatt tcgaatacga aaaggattca ttcccacagc aatgacagtc attaaaaatt
     1381 gtgatattga gaaaacatac ccataaatcc ctaaaccag
//
LOCUS       DACDLM010000184         1361 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.192, whole genome shotgun sequence.
ACCESSION   DACDLM010000184 DACDLM010000000
VERSION     DACDLM010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1361
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.192"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            164..778
                     /locus_tag="IV356_002981"
                     /pseudo
     CDS             164..778
                     /locus_tag="IV356_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(1148..>1361)
                     /locus_tag="IV356_002982"
     CDS             complement(1148..>1361)
                     /locus_tag="IV356_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HAP9016584.1"
                     /translation="KLSKSGILKEEYDSSFDEYPSRYILISEDYKKFKRYFLKNEKKI
                     SVIMEKYKAPIQADPFSNLDESDLPF"
BASE COUNT          496 a          214 c          203 g          448 t
ORIGIN      
        1 attctttttc ttctattata aactatttaa cttttagaat tcaaaaaccg tttgtctatt
       61 tagagtttac cctaaataga caaaaatata acattgaaaa atttagagtt ctaacgtatg
      121 attagggtgt attataaacg ttatagaaaa gtagggaata aatttgaaaa ttgcttatat
      181 tagagtttca tccatcgatc aaaatgaaca acgtcaaatt gaagaaatga aaaagtttgg
      241 cgctgaaaaa atttttatcg aaaaacaatc tggagcgacg attagtcatc ggccgatttt
      301 ccaggaagct ttagattttg tcagagagca agatattttt attgtagaag ccattgatcg
      361 acttggacgc aattatgacg agattatcga ttcagtgaat tatctaaaga agaagaatgt
      421 gcgacttatt atcaccagtt taccgatcat ggctgaagca attggaaatc ctctcctaga
      481 taaattcatc aaagacttaa tcatttaaat ctcagccatg attgctgaac aagaacgtac
      541 tgaatcgaaa cgacgccagg cacaaggaat taaaatcgct aaagcaaacg gcgtctataa
      601 aggtcgtcct aagttataca gtgcagacac caaagatcct caacgtcgcc ttgtctatag
      661 gagtatcgtt caggatcttg agaatggggt tgctatctca aagattgcaa cagactacaa
      721 tgtgactagg caaacaattt accgaataaa aaaagaaatc gaccaactaa ttgtatgatt
      781 tcttttttga atcacgtaat tattaattag ctttgtcatc aatacagaca atcattttag
      841 attcatctag ctaagttgat tacatttatg ttaaaaagaa tttagttaac ataaatataa
      901 ttgatgcata aatcgtcctt atttaaaggc atttaacatt gacaacttag tataatgtat
      961 cttatgtaaa ctaataagat ttgaatttta ttttatacac actcgataat agatcaattt
     1021 tatggtcccc cgcatttacg attgcacaag agaaacataa agtcgaccta ttagcatttc
     1081 ttttcaattc aaacattaaa aaagtttata cctctgctac taaaaaatga aattatctat
     1141 ttaaaattta aaacggtaaa tctgattcat ccaaattgga aaatggatca gcctgtattg
     1201 gagctttgta tttctccata ataacagata tctttttttc attttttaaa aaataccttt
     1261 taaatttctt atagtcctct gaaatcaaaa tatagcgtga tggatactca tcaaaagaag
     1321 aatcgtattc ttcctttaaa attcccgatt tacttaattt t
//
LOCUS       DACDLM010000185         1351 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.193, whole genome shotgun sequence.
ACCESSION   DACDLM010000185 DACDLM010000000
VERSION     DACDLM010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1351
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.193"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..785
                     /locus_tag="IV356_002983"
     CDS             <1..785
                     /locus_tag="IV356_002983"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016585.1"
                     /translation="KDKIFKFLLLFTMPILLKTVADGYLSRNNIAVYLAFIGIYLVKE
                     KYIPKTVAKFSLLIIIPIGLFLFYIMSQIRLGTQSDISFWQGTWNLIDSESSYPQYYD
                     YANQGNSNVNIINFIIYIFIVCIPSSFYDLIHFSIPNLAYTFTETILGLSYGETNNYY
                     ILLPSVLGEAIMLCGKYFAFTYAFIYGIVSTWFLRLLKRNKSLEYLLIYYLLDFFRQF
                     RGGSQYVITAWETQLVPLIIIVFFYKLVIKNGVAKERNEYNV"
     gene            778..1074
                     /locus_tag="IV356_002984"
                     /pseudo
     CDS             778..1074
                     /locus_tag="IV356_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003704837.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
BASE COUNT          511 a          145 c          233 g          462 t
ORIGIN      
        1 taaaagataa aatatttaaa tttcttctac tatttactat gccgattctt ttaaaaacag
       61 tggctgatgg atatttatca agaaataata ttgcggtata cttagcgttt attggtatat
      121 acttagttaa ggaaaaatat attccaaaaa cagtggcaaa attttcttta ttaattatta
      181 taccaatagg actattttta ttctatataa tgtcacaaat aagacttgga actcaaagtg
      241 atataagctt ttggcaagga acatggaatt taatagatag tgaaagttca tatcctcaat
      301 actacgatta tgcaaaccaa ggaaatagta atgtaaatat aattaatttt attatatata
      361 tatttattgt atgcatacca tcaagcttct atgatttgat tcatttttca attccaaatt
      421 tagcgtatac tttcacagaa actatattgg gtttgtctta tggggagaca aataattatt
      481 atattttatt accatctgta ttaggagaag ctataatgct ctgtggtaag tacttcgcat
      541 ttacctacgc gtttatctat ggtattgttt caacttggtt tttgagattg cttaaaagaa
      601 ataagtcttt agaatattta ctaatttatt atttattaga tttctttagg caatttcgtg
      661 gtgggagcca gtatgttata actgcatggg aaacccaatt ggttccttta ataataatag
      721 tattctttta taaattagtg ataaaaaatg gagtagcgaa agagaggaat gaatacaatg
      781 tgtgaagttt ctataataat tccaagctac aagggaagca acgaaatact aattgctgta
      841 tggggagcgt tgtcacaaac agtgacatcg aaggagataa ttgtcgtaga tgataatgga
      901 attggaacag aagaacagat aaaaacaaaa gaaaaattac aaaaatttat aaaagaaaat
      961 aaaataaagt attttgcgca tgaaaaaaat ttaaatggtt cagctgcaag gaatactggg
     1021 ataaaagcta gtaatggaaa gtatatagct tttttagatg acgatgatta tattattcca
     1081 tctaaattag aagagcaaat taatgtatta gaaaaaacac caaaagaagt tggtatgtca
     1141 gtatgtgaag gatattatgt tcataaagat ggcaaaggtt atttaaaaaa aataaaggga
     1201 aattatgtcg cattagataa atacttatta gataaacatt attttaatac gagttctatt
     1261 gttataaaaa gagagtgttt gattgacatg aaaggctttg atgattcttt tatacggcat
     1321 caagattggg aattttgtac gcgaatgcta t
//
LOCUS       DACDLM010000186         1350 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.194, whole genome shotgun sequence.
ACCESSION   DACDLM010000186 DACDLM010000000
VERSION     DACDLM010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.194"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            76..>1350
                     /locus_tag="IV356_002985"
     CDS             76..>1350
                     /locus_tag="IV356_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HAP9016586.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLIN"
BASE COUNT          459 a          261 c          257 g          373 t
ORIGIN      
        1 ggtattaaaa aacatatcgt tctctagtat gattaaatca ccacaaaata aacaactgag
       61 aggacgatac gctatatgaa tgattctatc aaaaaaatgc tgagaataac agagaaagat
      121 ttgatgatta cagaggtctc ttacgagacc cttcagaaga aaaagacgtt ggtcgtcgat
      181 gctgttctct cgcctactcc tcgtgcttgt agaagttgtg gttctactgt ggtagatgga
      241 aacgggaaag caattatagt gaaaaatgga aaaaaggaaa cgattgtccg ttttgaacaa
      301 tacaatcata tgcctttggt tatgcgccta aaaaagcaac gctatacctg taaaaactgt
      361 cgcacccatt ggacggctca aagttatttt gtccaaccca gacattcaat cgcaaatcat
      421 gttagatata aaattgcttc tttactgact gaaaaagtat ctttatcttt tattgcgaaa
      481 agctgtcagg tatctttgac caccgttatt cgtacattga aagagtttaa aagctattta
      541 ccaaagcaat ctaagaagat cctccccaga gtattgatgg ttgacgaatt tcgttcgcat
      601 gcttccatag aagataagat gagctttatt tgcgcggatg gcgaaacagg aaaattaata
      661 gatgttttgc ctacgcgtaa attacctcga ttaacaagct atttcttagg ttgtaccaat
      721 ccagaagaag tagaattctt ggtgacagac atgaacgccg cctacttcca gctcaccaaa
      781 cgtgttctgc caaatgcgaa agtcgtgatt gatcggtttc atattgtcaa acacatgaat
      841 caagcgttca atgagttgcg tatccgtgaa atgaatgaac ttcgtaaagc cggacagaaa
      901 agccaggcag aaaaactgaa aaagaactgg cgctttttgc taaaaaatcg tgcaaacatc
      961 aaccattatg aatacaaaac atggaaaagt ttccgagcac caaaataccc atttcttact
     1021 gaagcaatga tgattgatcg attgcttgag ttttctccgc ccctaaagga ggcgtatccc
     1081 ttttttcatg aattagttga agcctttcga gacaaagacc ctgacttatt tttctcctta
     1141 ttggcagaac ttcccgaaac gttagatgac agctttcggg aaaagcttca aaaccttctg
     1201 acctatgaag aaggcatcac caacgcaatg atctatcctt attccaatgg aaaaatagaa
     1261 gcgaagaata cccacataaa gacaatgaaa cgagtatcct acggatttaa atcatttgag
     1321 aacatgagaa ttagaatctt tttgatcaat
//
LOCUS       DACDLM010000187         1349 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.195, whole genome shotgun sequence.
ACCESSION   DACDLM010000187 DACDLM010000000
VERSION     DACDLM010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1349
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.195"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            23..1324
                     /locus_tag="IV356_002986"
     CDS             23..1324
                     /locus_tag="IV356_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP9016587.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT          439 a          270 c          251 g          389 t
ORIGIN      
        1 cacaatcaaa ggagcgttct gtatgcctga tcttcatcat atcaaactac tacttggaat
       61 caaagataaa aacattttca tcacaaatgt ggaatcgaag agcattaaga atatcaagag
      121 tcttgttgtt tctgcgacgt taagtaaaga aattcgtcgc tgtcctttgt gtaaacagat
      181 gaatcatgaa ggcatgatcg ttaagaacgg aaagaaaaaa tcgctcattc aacttaataa
      241 atgtgcgaac caactgactt atcttgcttt agcgaaacaa cgctaccact gtcgtggctg
      301 ccacacctat tttacggcga atacctacat tgtcgataga aactgcttta tcgctaaaca
      361 agtgcgctat aaaattttag aagagctaac tgaaaaacaa gcaatgacga caattgctaa
      421 gcattgcggc gtttcttggt cgaccgtttc tcggacactc gcttctctga tccccatgac
      481 aaaagtaaaa agaaattggt taccgcgttg tttattaatg gatgaatttc gttcactgaa
      541 aaatcaagtc ggtccctact ccttttcttg tatggatggc gatactggaa aattactgga
      601 tattcttcct tcacggaaga aaaaggctct cgtttcttat tttatgcaat ttgaacgacg
      661 cgcacgattg aaggtaaagg tcatcgtgac ggacatgaat gtttcttatg cctctctgat
      721 aaaggaatgt tttccaaagg caaaactcgt tgtggatcgt tttcacattg tcaaacatct
      781 cattcgtaaa tttgaggata ttcgcgtacg aatcatgaaa agctttgatc gaaacgatcc
      841 aacacaagcc aaatattatc gacaattaaa ggcgttgtct cggcttctga tcaaacgaca
      901 ggacaagctt gtttatgaca aatggaccaa atggcgcaat tttggttggg cgtatctcac
      961 cgaaagtgaa gtggtggatc gtctgctttc gatctctgac gaattacgaa tcgcctattt
     1021 ttactatcaa gaaattcttc aagcgtttca cgacaaagag gcggacactt tctttaaact
     1081 tgtaagaacg atgcccaatt ccgttccaaa agaactgcat tctataaaaa aagcttttat
     1141 aaactatgaa tccggcattc gtttagccct cgaattgcct tattcaaatg ccaaaataga
     1201 aaatctgcat acccacatca aagcattgaa acgagtcgct tatggctttc gaagctttcg
     1261 gaaaatgaag accagaattt tcttactaaa taatctgatt acctatgaat caaaaaacat
     1321 ctaaagtaga aaaggaattc taccttaga
//
LOCUS       DACDLM010000188         1347 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.196, whole genome shotgun sequence.
ACCESSION   DACDLM010000188 DACDLM010000000
VERSION     DACDLM010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1347
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.196"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..1343
                     /locus_tag="IV356_002987"
     rRNA            <1..1343
                     /locus_tag="IV356_002987"
                     /product="23S ribosomal RNA"
BASE COUNT          362 a          295 c          408 g          282 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaagcgaag gtacgaattg aagccccagt aaacggcggc cgtaactata
      361 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa
      421 cgatttgggc actgtctcaa cgagagactc ggtgaaattt tagtacctgt gaagatgcag
      481 gttacccgcg acaggacgga aagaccccat ggagctttac tgtagtttga tattgagtgt
      541 ctgtaccgca tgtacaggat aggtaggagc cgtagaaatc ggaacgctag tttcgatgga
      601 ggcgctggtg ggatactacc cctgcgttat ggccactcta acccgcacca ctaatcgtgg
      661 tgggagacag tgtcagatgg gcagtttgac tggggcggtc gcctcctaaa aggtaacgga
      721 ggcgcccaaa ggttccctca gaatggttgg aaatcattcg aagagtgtaa aggcagaagg
      781 gagcttgact gcgagaccaa caagtcgagc agggacgaaa gtcgggctta gtgatccggt
      841 ggttccgcat ggaagggcca tcgctcaacg gataaaagct accctgggga taacaggctt
      901 atctccccca agagtccaca tcgacgggga ggtttggcac ctcgatgtcg gctcgtcgca
      961 tcctggggct gtagtcggtc ccaagggttg ggctgttcgc ccattaaagc ggcacgcgag
     1021 ctgggttcag aacgtcgtga gacagttcgg tccctatccg tcgcgggcgt tggaaatttg
     1081 agaggagctg tccttagtac gagaggaccg ggatggactt accgctggtg taccagttgt
     1141 tctgccaagg gcattgctgg gtagctatgt agggaaggga taaacgctga aagcatctaa
     1201 gtgtgaagcc cacctcaaga tgagatttcc catttcttta agaaagtaag atccctgaga
     1261 gatgatcagg tagataggtc aggagtggaa gtacagtgat gtatggagcg gactgatact
     1321 aatcgatcga ggacttaacc aataggt
//
LOCUS       DACDLM010000189         1336 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.197, whole genome shotgun sequence.
ACCESSION   DACDLM010000189 DACDLM010000000
VERSION     DACDLM010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1336
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.197"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..246)
                     /locus_tag="IV356_002988"
     CDS             complement(<1..246)
                     /locus_tag="IV356_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002384409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP9016588.1"
                     /translation="MEVIIMNVGFIGAGKVGCSFGKYFQEHKIQVTGFYSKSEDSSLA
                     ASNFTSSKQYLNLRELVDENDTIFITTPDGQIQEVWQE"
     gene            484..>1336
                     /locus_tag="IV356_002989"
     CDS             484..>1336
                     /locus_tag="IV356_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP9016589.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGRKEICEDFKLV
                     YQANSKEE"
BASE COUNT          474 a          217 c          228 g          417 t
ORIGIN      
        1 ttcttgccat acctcctgaa tttgaccatc aggagtcgta atgaaaatag tatcattttc
       61 atctactaat tctcttaagt ttaaatattg tttactagat gtaaaattcg aagctgctaa
      121 tgacgagtct tcgcttttac tataaaatcc tgttacttgt attttatgtt cctggaaata
      181 cttcccgaat gaacaaccta ccttgccggc tccaataaaa ccaacgttca taattatcac
      241 ctccataaag aagtgagact acaagtccca ttcttacgat atgagcttaa aaataaaaat
      301 taaatcaaat atacagtatg tttttttcaa atatcatcca tagttaattt atcataatat
      361 cccatatttt aaaataaaag atagcgtaaa atattttgtg taaatagaaa tttagggtag
      421 aaaaaaaagt ccattctgta aaattaaagt taccacacag aaattttata ggaggacttt
      481 ctcatgacta aatttactat agaaattatg caaacactac tcaataaagg ggatttagat
      541 gaattatttc aggatcattt agagcgagcg attaattcac ttctacaagc agagctaact
      601 gcttttttag attacgaaaa atatgatcga aatggattca attcaggaaa ttcccgtaac
      661 gggaattatt cacgtacatt taaaacagaa tatggcgagt tgaatttaac tattcctaga
      721 gatcggaatg gcgaattttc tcaacaaaca ctaccagcat ataagcgaac caatgattca
      781 ttagaaacga ccattatcca attatttcaa aaaggcatta ctatggctga aatctccaaa
      841 ttaattgaaa aaatgtatgg tcaccactat acgccacaaa caatctccaa catgagtaaa
      901 ttggtggctg aagatgtttt agcttttaaa gaaagaacgt tagaagccaa ttattccgtt
      961 atatttatgg atgcgacgca tatccctgtg aagcgacaga ctgtttcgaa ggaagcagtg
     1021 tatattacga ttggtattcg tttggatgga accaaagaag ttcttgggtt tactattgcc
     1081 ccaactgagt ctgcttatat ttggaaagaa gttcttcaag atcttagaaa acgtgggtta
     1141 gaagaagttt tattagtagt gacagacgga ttaagctgta ttgaagaaag tatccatagt
     1201 gtgtatccga atgcccaatt tcaacaatgt tgtgtgcatg tatctagaaa tatcgctcat
     1261 aaagttcgtg ttcgaggtcg aaaagaaatt tgtgaggatt tcaaattggt ttaccaagcg
     1321 aattcaaaag aagagg
//
LOCUS       DACDLM010000190         1332 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.198, whole genome shotgun sequence.
ACCESSION   DACDLM010000190 DACDLM010000000
VERSION     DACDLM010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1332
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.198"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            82..>1332
                     /locus_tag="IV356_002990"
     CDS             82..>1332
                     /locus_tag="IV356_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP9016590.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFK"
BASE COUNT          419 a          262 c          255 g          396 t
ORIGIN      
        1 tttttgtata aaaaaatata gaaaagacac cctgaaatcc tttagaatta atttggctac
       61 caattcatag gaggattcaa gatgtctcat actcagctta tcaaagatac cctaaatatt
      121 ctagacctaa atatctattt cgaggaaaat tgtttaacta aagaaaaata caaagggcaa
      181 atttgcttga tttacaaagg aactcttctg tacaagccag aagagtgttc ccattgtctt
      241 tgtgtcgtcc cctctaggat cattcgttgg gggacgacaa ccgttcggtt gttactgaat
      301 gatgtgtctg agtatcgcac ttatctggag ctgaagaaac aacgatttaa atgtaagtct
      361 tgccaaagaa cattcgtagc ggatacctct gttgctgaaa aacactgttt cattagtcaa
      421 aaagttcgtt ggtctgtcat tgctcgctta aaagagaata cttccatgac ggaaatcgct
      481 cgtcagaaaa atatttccac ttcttcggtc tatcgtgtca tgaagcgatt ctaccgccca
      541 ttgaatcctt tcaaacagac tttgccaaag gtcttatgct ttgatgaatt caaatcggtt
      601 cgaagtgttg ccagtgcaat gagttttatc atgatggacg gacaaagcca tgcattattg
      661 gatattgtcg aaaatcgacg cttgccttat ttagaacgct atttttctcg gttttcatta
      721 gcgactcgtg aagccgttca attgattgtt attgatatgt atgcgcctta tgtttcgttg
      781 gtgaaaaagc ttttcccgaa tgctcagttg atcatcgatc gtttccacat cgtccaacat
      841 attggcagaa ctttcttgaa tcatcgagtg aaagaaacca cggtacgact taaaggaaat
      901 tcccactctc aacgagggtt agggaaaaaa ttgaagcgct attggaaact cctacaaaaa
      961 gaagaagcaa agttaaacta tgaaaaacgg gtttggcgtg ccagttttaa agattatttg
     1021 actgaaagtg agattgccga tcgactgtta gctgcttgtc ccaacttacg ccaaggctat
     1081 cagttatacc aagacattct ttatgcggta aagaaaagag atcagtcact atttgaggat
     1141 tgtttaacta gagacattag cggtctgcca gaaacctata caaccacttt acgaacgttt
     1201 aaaaagtttc tgccacagat ccaaaatgcg cttcactaca gctattcaaa cggaccattg
     1261 gaatgcttaa acaaccacat caaagtatta aaacgcaatg cgtacggctt tcgcaacttt
     1321 tacaatttca aa
//
LOCUS       DACDLM010000191         1313 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.199, whole genome shotgun sequence.
ACCESSION   DACDLM010000191 DACDLM010000000
VERSION     DACDLM010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1313
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.199"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(190..801)
                     /locus_tag="IV356_002991"
     CDS             complement(190..801)
                     /locus_tag="IV356_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP9016591.1"
                     /translation="MGIQIISLSDLLEVAPDLESVNSILKTFKSIPHPITGQVNDVEY
                     FLHQKAIEFEKAALATTHLLFSSYKDKSILVGYFSLANKSLIMSKKNYNNLSKPQQRR
                     LCQNGSKTETGGYIVNSYLIGQVGKNYSDEAQKIDAINGTQILTIAYDTVLQAKKIIN
                     ARYVWIECENIPRLIDFYRDFGFEVIENYETNSGLVVMVMKLK"
BASE COUNT          450 a          227 c          154 g          482 t
ORIGIN      
        1 taaatacttc atatcaatca tttattcaga aacaaactat cttgcaggat ctatacgagt
       61 taattacaga gcaaaaaagc ctcaaccaag gatgactggt tgaggttttt gttttacaaa
      121 tttaaatctt tttaagttca ctatacgctt gtttaacctt gtaatagata catgcaataa
      181 ttagttttac tattttaact tcataaccat tacaactaat ccactgtttg tttcataatt
      241 ttcaataacc tcaaaaccaa agtctctata gaaatcaatt aacctcggaa tattttcaca
      301 ttcgatccat acatatctag cattaataat tttttttgcc tgcaaaaccg tatcataagc
      361 tatcgtcaat atctgggttc catttatagc atctatcttt tgagcttcat cagaatagtt
      421 tttgccaact tgtcctatca aataactatt aactatgtaa ccaccagttt cagtttttga
      481 accattctga cacaatcttc tttgttgggg cttactgaga ttgttataat tttttttgct
      541 cataattaag gatttgttag ctaaagaaaa ataaccaact aatatagatt tatctttata
      601 tgagctaaat aaaagatgcg tagttgctaa agcggctttc tcaaattcta ttgctttttg
      661 atgcaaaaaa tattccacat cattaacttg accagttata ggatgtggaa tagatttaaa
      721 tgtctttagt atgctattta cactttctaa atccggagca acctctaata aatcacttaa
      781 actgataatc tgtattccca tctaactatt acttccaaaa aaaatatttt ttattttttc
      841 tttgtcatcg attactttta aattagttac caactgtttt ctaggtgatt tatcattaga
      901 taatgcatta attaaagagt tagcattctt ttttgtaaac ctatactcct cagtaaaact
      961 tttagtagcc ataacaatcg cctccgttta tgtaccaaca caaaaatata taggaaaaaa
     1021 cacgtcaaaa taacgtactt gtacaaaaca atcatacatc attttacgct ttaactttcc
     1081 tttgttgtaa gttcaatata ccatcattgg tttaattgta caagagaaac ggctaaaaaa
     1141 tcagctaatt ttgttagcaa ctttgttagc atatctgaca gtagatcaat agtaaaagtg
     1201 cctgtatata aggaaaaact gtatttttac tatctaaatt cgtaaacatt tttgcttaca
     1261 aattagctaa taatattagc aactatattg aaaactatat gtactgcccc tca
//
LOCUS       DACDLM010000192         1312 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.200, whole genome shotgun sequence.
ACCESSION   DACDLM010000192 DACDLM010000000
VERSION     DACDLM010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.200"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(156..1297)
                     /locus_tag="IV356_002992"
     CDS             complement(join(156..1069,1069..1297))
                     /locus_tag="IV356_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAP9016592.1"
                     /translation="MAKAKKKFDEDFKKMILDLNQSGQSVEELAAQYGIATQTIYRWK
                     KLHTKNVATGMTEAEILAMKKEMARMQEENTIPKKGFNHIRSKVKMSDVFEFIQSNVH
                     DHDVKQMCTVLEAPKSSYYDWKKKKPSKRQSENKRLNRLISGIYFENKGIYGAPKIHK
                     ILVGRGETLSLKKVQILMRKLGLRSVTLKKYKPGKQAKVKSEGRKNLLNQDFTTTSIN
                     QKWVTDITYIHTLKDGWTYLSTIQDLHTKKVIGWKFGKQMTKELVIETLDNALLNQTP
                     SENLIIHSDLGSQYTSEAYEAKLNELNIRHSFSRKGCPYDNAGIESFHASLKKEEVYP
                     SKAYENFEAAYLALFQYIEGFYNRKRIHSSINYLTPNQMEELALQA"
BASE COUNT          323 a          263 c          278 g          448 t
ORIGIN      
        1 gacacgattt gtgagaattt tttcgagatt ccagcgggtg agtatctcat cgtttcgacc
       61 agcggtcaaa ccaaaaccgt ttgaccgctg atcgaagcga tgaagttgaa accctgtgga
      121 aatctcgcca aaaaaatgta agtggtagct aggaactaag cttgcaatgc caactcctcc
      181 atctgatttg gtgttaaata gttgatacta ctatggattc gcttgcgatt gtaaaatcct
      241 tcaatgtatt gaaataacgc taaataagca gcttcaaagt tttcatacgc ttttgatgga
      301 tagacttctt cttttttgag tgaggcgtga aacgattcga taccggcatt atcgtaggga
      361 cagcccttac gactgaagga gtgccgaatg ttcaattcat tcagctttgc ctcataggct
      421 tcgctagtgt actgagaacc caaatctgag tggatgatca agttctcgga gggtgtttgg
      481 tttaagagcg cattgtcaag ggtttcgata accaattctt tcgtcatctg cttgccaaac
      541 ttccaaccga tgactttctt tgtgtggagg tcttgaatag tggagaggta ggtccagcca
      601 tcttttaggg tatgaatata ggtaatatct gtcacccatt tttgattgat cgacgtagtg
      661 gtaaaatctt ggtttaacag gtttttacgt ccttcacttt taactttcgc ttgtttgcca
      721 ggcttgtact tcttgagggt gactgaacgc aagcctaatt ttctcatcag tatttgtact
      781 ttctttaagg acaaggtctc gccacggcca acaagaatct tatgaatttt aggcgcacca
      841 tagataccct tgttttcaaa gtagattcct gaaatcaagc ggtttaagcg tttgttttct
      901 gattggcgct tggaaggttt ctttttcttc cagtcatagt agctggattt cggtgcttcc
      961 aaaacggtac acatttgttt tacgtcatga tcatgaacat ttgattgaat aaattcgaag
     1021 acatcactca tttttacttt tgagcgaata tggttaaagc cttttttagg atagtgtttt
     1081 cctcctgcat gcgggccatt tcctttttca tcgctaggat ttctgcctca gtcatgccgg
     1141 ttgctacatt ctttgtatga agcttcttcc aacgataaat cgtttgtgta gcgataccat
     1201 attgcgctgc cagttcttcg accgattggc cagactggtt taaatctaag atcatcttct
     1261 taaagtcttc atcaaatttt ttcttggctt ttgccatcgt ggacacgtcc tt
//
LOCUS       DACDLM010000193         1311 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.201, whole genome shotgun sequence.
ACCESSION   DACDLM010000193 DACDLM010000000
VERSION     DACDLM010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1311
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.201"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            200..1248
                     /locus_tag="IV356_002993"
                     /pseudo
     CDS             200..1248
                     /locus_tag="IV356_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180785.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
BASE COUNT          532 a          148 c          255 g          376 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccagatgg aatggcaaca
     1261 ctttttttga caaaaattat aaggtgttgt gaatgctgcg gtgttatggc t
//
LOCUS       DACDLM010000194         1290 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.202, whole genome shotgun sequence.
ACCESSION   DACDLM010000194 DACDLM010000000
VERSION     DACDLM010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1290
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.202"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(62..280)
                     /locus_tag="IV356_002994"
                     /pseudo
     CDS             complement(62..280)
                     /locus_tag="IV356_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(546..740)
                     /locus_tag="IV356_002995"
     CDS             complement(546..740)
                     /locus_tag="IV356_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016593.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
BASE COUNT          457 a          217 c          175 g          441 t
ORIGIN      
        1 taggtatttt tattatatat agatttaaca tatgtcggtc ggttgattga tatagctaaa
       61 gttataactc aaccgaagcc gattcatcta cacgaataaa gttgcgagtg ttctcggcta
      121 attcataaaa attgttatgt gttccatata gcaatactgg aataacttta ttttcttgaa
      181 tctcataagc aactctatac acggtgaccg catacttaaa tccattagac caattacctg
      241 ataaacctcc agttttttgc tcttacttaa atggatcaat ggcaatttca tcacaaacct
      301 atagaggatg agtgacttct gcctaattac gttaaaaaat attgaaagta actctatgta
      361 gcaaaaaata tctagaattt catttcctca aaactgatcg atattgtatc taaaaatata
      421 tactacctaa aataggtagt atatattaaa atatgtgctt ttgttagaaa aatcaataca
      481 taaattatca tatctgtata tgtcatttag gtatttcagt tatgttataa tagttttgct
      541 gtctgctacc ccggcctaat ctggcaaggg gaggaggaga tataatgaaa tacctttttg
      601 attttgtttt tgcaatcaag ccacttgcag atgtagtgtg cagttacctc tgcaaatggc
      661 ttgattgcaa aattgccaaa aaagacagta agcctacccg ttaattctat aatatagaaa
      721 cgtaaaaaaa accccatcag cctgcacgct gatggggttt ggtgatataa tgaaatacct
      781 ctttgttact cataattata ccataattag tcacgaatgc aaccaataga aaaaactact
      841 tagaacggta gatcatcgct aataacaatg cattgtccac caaatggatt ttgtgaagca
      901 ttaaatacat tgttattaat tgtcgctgct tttaactagg cctctcccct tctattataa
      961 aagaagatat atatcatttc ttaattacct actaccttaa accaaaattt aagtactacc
     1021 taatttaagt agtacttaaa caatctaaaa aatagttatc ccaattgtta tgcttttata
     1081 atacgattat ttgtaacaaa atgaatatta tataattaaa cactaccata tttaggtagt
     1141 gtttaattat tagcaaaaca aaaaatattt attctattct cttaacttca actaagttat
     1201 gctgcacacc tttatataaa tcatatgcaa ctcattagct agacaaacta caagcatgta
     1261 gttttatctg ttaattatgt actacctaaa
//
LOCUS       DACDLM010000195         1193 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.204, whole genome shotgun sequence.
ACCESSION   DACDLM010000195 DACDLM010000000
VERSION     DACDLM010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.204"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..1076
                     /locus_tag="IV356_002996"
     CDS             <1..1076
                     /locus_tag="IV356_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAP9016594.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          210 g          331 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tct
//
LOCUS       DACDLM010000196         1136 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.205, whole genome shotgun sequence.
ACCESSION   DACDLM010000196 DACDLM010000000
VERSION     DACDLM010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1136
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.205"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..355
                     /locus_tag="IV356_002997"
     CDS             <1..355
                     /locus_tag="IV356_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016595.1"
                     /translation="GAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETNMTRDELL
                     RKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTTSQIKQDT
                     EDSLRKGWGMNNKVR"
     gene            615..985
                     /locus_tag="IV356_002998"
                     /pseudo
     CDS             615..985
                     /locus_tag="IV356_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            985..>1136
                     /locus_tag="IV356_002999"
     CDS             985..>1136
                     /locus_tag="IV356_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAP9016596.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWV"
BASE COUNT          430 a          135 c          237 g          334 t
ORIGIN      
        1 tggcgcacca atcagaaagt ttgataaggt ttattccacc aagcatcctt taaaactgtc
       61 gactttgtta aatgcgactt ccagagtttt agtagaaaag tatgagacta atatgacaag
      121 agatgaattg cttagaaaag ctttagatga gtatattaaa cagaatctta cgcaagaaga
      181 taagcaagat ttgtttaatg acgtggtgaa agaactagac ttgttcagag aaaaatatcc
      241 aattgttcca gaattagatg atcgtggaga aataataaga actaccagtc agataaaaca
      301 agataccgaa gactcactgc gcaaagggtg gggaatgaat aataaagtta gataataatc
      361 aaagaagaac taagtaacta cctttaaacg gtagttactt agttcttctt tgatttgcat
      421 gaaatagagg ggatttattt ttctggttac gtgattaaaa aatccaaaaa atgagcatag
      481 gaacggttat gattttaggg tgtgttttaa tgagatattg tgatttcatt aacaagtgta
      541 tgataatctg ttgttgagtt agtaaataag taatagagct aactctaaaa taaaactatt
      601 aggaggagat gtaggtgaaa aagtttaaaa agaaaatata tttaggattg gttgttgggg
      661 tgagtatgtt tgggttcatg gctcatacta aacaagtaac tgcagatact aaccaaaaag
      721 aaaggattat gagccaatta gatgactctc aaataagtat gtacccaatg agctaattgt
      781 cagtttaaag gctacacaaa gaatttcaac agagaaaaat aaaccgcaaa atttattggg
      841 tgtaaaagtt atggtggaaa aagatttgac tcttaggaca aatgaaagcg attgtaataa
      901 gcgagatcaa gggttctgtt gcaaagtttt ccaaaaaatc tattttagtg taaaattgag
      961 aaaaaagaca gagaggacag agtaatgaat cattttaaag gcaaacaatt caaaaaagac
     1021 gtcattattg tcgctgttgg ttactacctg cgttacaatc taagctatcg tgaagttcag
     1081 gaattgttat atgatcgtgg aataaatgtt tgtcatacta cgatttatcg ttgggt
//
LOCUS       DACDLM010000197         1125 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.206, whole genome shotgun sequence.
ACCESSION   DACDLM010000197 DACDLM010000000
VERSION     DACDLM010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1125
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.206"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            2..667
                     /locus_tag="IV356_003000"
     CDS             2..667
                     /locus_tag="IV356_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016597.1"
                     /translation="MAYYLLSEPKQIAASNIFTAVMTLMCVMCFSIFSYLLVQFIRQN
                     LTMSKLFKSLLDLLILGSMLTTLTDRFEQSEKTVEGIKNFLTTIDQFINGYMYLFEVG
                     FILTLFGCVFIKLIKRSIEKEMVIDLIPTLSGYEYYVDFGKYEELIHTDIVHTSIHEV
                     TVKGIRSTLKDGQETKTIDQRKEVYNFYKVEASLRYGIGKLRLDGSNIQQNKPYVLGK
                     VVI"
     gene            711..980
                     /locus_tag="IV356_003001"
     CDS             711..980
                     /locus_tag="IV356_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016598.1"
                     /translation="MILLYRIVLIVGTELKILKKEQLFKVKEHHNQLLCIKTGTMNIQ
                     YRTEYLELTNQTDFLSIREQHKQEKLMATYSQLIDEWEQFKESKT"
BASE COUNT          412 a          158 c          218 g          337 t
ORIGIN      
        1 ggtggcctat tacttgttaa gtgagccaaa acagatcgcg gcgtcaaata ttttcacggc
       61 agtaatgaca ttaatgtgtg tcatgtgctt ttctattttt agttacttac tcgtccaatt
      121 tatcaggcaa aatttaacaa tgagtaaact tttcaaaagt ttattggact tacttatctt
      181 aggcagtatg ttaacgactc taacagatcg gttcgaacaa tctgaaaaaa cggtagaggg
      241 gataaagaac ttcttaacga cgattgatca atttataaat ggatatatgt atttgtttga
      301 agtaggcttt attctcactt tgtttggttg tgtatttata aaactcatta aaagatcaat
      361 cgaaaaagaa atggttattg atctaattcc gacgctgagc ggctatgagt attacgttga
      421 ttttggaaag tatgaggagt tgatccatac ggatatcgtt cacacgagta tccatgaagt
      481 aaccgttaag ggcatcagat ctactttaaa agatggacag gagacgaaaa caatcgacca
      541 aagaaaagag gtctacaatt tttataaagt tgaagcaagt ctacgatatg gcattgggaa
      601 attgaggtta gatgggagta atattcaaca aaacaaacca tatgttttag gaaaagtggt
      661 gatttagaac ttcctatgaa agatgaataa ataaggagaa tcttttgaaa atgattcttc
      721 tttacagaat tgtgcttata gttggcacgg agttaaaaat cttaaagaag gagcagttat
      781 tcaaagtgaa agaacatcat aatcagttac tatgtattaa aacgggtacg atgaacattc
      841 aataccgaac agaatattta gaattaacga atcaaactga ttttttgtcg attcgagagc
      901 aacataagca agaaaaatta atggctactt atagccaatt gattgatgag tgggaacaat
      961 tcaaggaatc taaaacataa aattccattt aaacacctta ttttttaaag agcataagga
     1021 aacgtgaccc cacttttaaa aaaagtggtt ggataggctg tgcctatcac gtttctgaaa
     1081 aaaataaatg accccaaaat accaatatat aggatagtac aagga
//
LOCUS       DACDLM010000198         1114 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.207, whole genome shotgun sequence.
ACCESSION   DACDLM010000198 DACDLM010000000
VERSION     DACDLM010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1114
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.207"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(1..345)
                     /locus_tag="IV356_003002"
                     /pseudo
     CDS             complement(1..345)
                     /locus_tag="IV356_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            421..576
                     /locus_tag="IV356_003003"
                     /pseudo
     CDS             421..576
                     /locus_tag="IV356_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
     gene            595..>1114
                     /locus_tag="IV356_003004"
     CDS             595..>1114
                     /locus_tag="IV356_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP9016599.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLE"
BASE COUNT          398 a          133 c          201 g          382 t
ORIGIN      
        1 tatttagaat tttgcacatc gctgatatgg aatatttatg cttgttggca tcaattactt
       61 gtcttttcgt ccgaatatca gcgccgcttg ctttaaaata tcattctcca tttcgagttg
      121 cttatttttc tttcttagtg cgatcaattc tgcttgttct ggtgttaagt tgtctctttc
      181 tttgaatgag cccgttgatt gtgcttgctt catccattta tcgaaagaag aaggcgtaag
      241 ctcatactct cgaataattt ctgcgcgagg cttaccagcg agatagagat cgacgatttg
      301 ttgtttgaat tcttttgaat aggttcttcg ttgacgtctt ggcatgaaaa atcctccagt
      361 gtgtttttta ttattctaca caccttattt tttctgtcta gtctagtgta gccgattcag
      421 gataaggata agtgtattaa ttgtggaaaa tgtaaaaaag tttgccaaat gaataaagat
      481 tcagttgaga attgcaatca tctggagtgt atcagatgtg gacgatgtaa aaatgcttgt
      541 ccagtggatg caattagtta tggagtaaga aaatagagag gagtagttag gaaagtgata
      601 aaaaatgcta tagcatatat tacaagaaag aaaaatagaa ctttaataat ttttatcata
      661 ttaactatag ttctttcttg cttgtattct tgtttaacaa taatgaaatc aagcaatgaa
      721 atagaaaagg ctttatatga aagttctaat tcttcaatat caataacaaa aaaagatggt
      781 aaatatttta atgttaatca atttaaagat attgaaaaat taaaagaaat tgaagaaaaa
      841 ataattcaat atgatggatt agcaaaacta aaagatgcta aagtagttag cggagaacaa
      901 agaataaata gagaagattt atctgacgaa tttaagaatg ttgtttcact cgaagctaca
      961 aataatacta aaagaaatat tttatttagt agtggagtat ttacaattaa agaaggtaaa
     1021 aatatagaag aaaatgataa gaattcaatt attgttcatg aagaatttgc taaacaaaac
     1081 aatctaaaat taggtgatga agttgatctt gaat
//
LOCUS       DACDLM010000199         1094 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.208, whole genome shotgun sequence.
ACCESSION   DACDLM010000199 DACDLM010000000
VERSION     DACDLM010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1094
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.208"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..153)
                     /locus_tag="IV356_003005"
     CDS             complement(<1..153)
                     /locus_tag="IV356_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAP9016600.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWV"
     gene            complement(475..696)
                     /locus_tag="IV356_003006"
     CDS             complement(475..696)
                     /locus_tag="IV356_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016601.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            complement(794..1039)
                     /locus_tag="IV356_003007"
     CDS             complement(794..1039)
                     /locus_tag="IV356_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016602.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
BASE COUNT          330 a          212 c          141 g          411 t
ORIGIN      
        1 tacccaacga taaatcgtag tatgacaaac atttattcca cgatcatata acaattcctg
       61 aacttcacga tagcttagat tgtaacgcag gtagtaacca acagcgacaa taatgacgtc
      121 ttttttgaat tgtttgcctt taaaatgatt cattactctg tcctctctgt cttttttctc
      181 aattttacac taaaatagat tttttggaaa actttgcaac agaaccgttt ttactatata
      241 cttcttccca gaacttgtcc gtctccttca aattatctct acctctcgag ttcattgggt
      301 ggtttgccca tttattaaac atggaatcac ctttctcata ctcatatatt tatgtcctat
      361 ttcaattata tttatatatg cttaaataaa tttgtatcct gaaatttatt gtaatatgaa
      421 gctgtatttt acatatagta accaaagagt taataaaata aaaagagcga accattatag
      481 atcagctctt ttttcattgc tgtttttaat cttatctaga atcacttcaa atgtttcaaa
      541 ggtatttaca tctaactgac ataaccaaag caagtacttc ttttctttgt aagtccaatc
      601 aatattacgg taagaggaca ttagattatg gtaccttgct ctttgttcaa ctgaagccaa
      661 ttcccagcgt ttttcaaata ttttttcttc ttccattatt gatccctcgc aagacgctac
      721 ctcaaactta aataatgggc agcgaaagtc taattcctta gatctaagta tagcaaacaa
      781 atatgaaaaa aacttagaag gtagtaaaag ttcttccgtc ttttgctttg cttctattct
      841 taatgtgttt cgttatcggt gccctacaaa gattttcatt aattacacac tcatttattg
      901 ttgtgtattt tctgacattt ctctcttgat caattatttt aattccatgg gcatcctgat
      961 agttcatagg agaggagcgg ctatcagaaa tagttgcacc tatctcttga acttctttta
     1021 caacttctgg aaaatccatc catcctgctt cagctgtcaa aagtaataat ctataatatt
     1081 tatctttcct tttc
//
LOCUS       DACDLM010000200         1089 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.209, whole genome shotgun sequence.
ACCESSION   DACDLM010000200 DACDLM010000000
VERSION     DACDLM010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1089
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.209"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            4..978
                     /locus_tag="IV356_003008"
     CDS             4..978
                     /locus_tag="IV356_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase family protein"
                     /protein_id="HAP9016603.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          382 a          135 c          187 g          385 t
ORIGIN      
        1 actatgtgta cgtctattac ttatgtaaca agtgatcatt attttggaag gaattttgat
       61 tatgaaatat cttacaatga agtagttact gttactccaa gaaattataa gttgaatttt
      121 cgaaaggtaa atgatttgga tactcattat gcaatgattg gtattgccgc tggtatagct
      181 gactaccctc tttattacga tgcgacaaat gaaaaaggat tgagtatggc tgggctaaat
      241 ttttctgggt atgctgatta taaagaaata caagaaggga aagacaatgt atctcctttt
      301 gaatttattc cttggatttt aggacaatgc tcaacagtag gagaaactaa aaaattgtta
      361 aaaaatatca atttagcaaa tataaattat agtgatgaac ttcctttatc ccctttacat
      421 tggctattag ctgataaaga aaaatcaatt gtcattgaaa gtatgaaaga tggacttcat
      481 atatatgata accctgtggg cgttcttacc aataatcctt catttgacta tcaattattt
      541 aatttaaaca attatcgtgt cttatcgagt gaaactccta aaaataattt ttcaaatcaa
      601 ataagtttga atgcctatag ccgcggtatg ggagggatag gcttgcctgg agatttatcc
      661 tcagtatctc gttttgttaa agcgactttt acgaagctga attctgtatc tggagattca
      721 gagtcagaaa gtattagtca atttttccat atcttaggtt cagtagaaca acaaaaaggt
      781 ttgtgtgatg ttggtgatgg aaaatatgaa tatacaattt attcttcttg ttgcaatgtt
      841 gacaaaggaa tctattatta tcgaacatat gaagacagtc aaattactgc aattgatatg
      901 aataaagaag acttagatag tcataagtta attagttatc caattataga aaaacaacaa
      961 attaaatata taaattagtt aatgtgttgt gattgattat ttaatataga tataatacaa
     1021 aaaggcaaag atattttcaa aacatttttt cttgatgtga tatccttgtc ttttttgtaa
     1081 tgtttttaa
//
LOCUS       DACDLM010000201         1088 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.210, whole genome shotgun sequence.
ACCESSION   DACDLM010000201 DACDLM010000000
VERSION     DACDLM010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1088
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.210"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..278
                     /locus_tag="IV356_003009"
     CDS             <1..278
                     /locus_tag="IV356_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAP9016604.1"
                     /translation="RNPFVSEYVKRLAKGICQLCQEKGPFIKDGVPYLHCHHIEYLSQ
                     GGKDVIENCIALCPNCHARIHELELPDDKEKLLKIVEKRENSFSKIP"
     gene            621..877
                     /locus_tag="IV356_003010"
                     /pseudo
     CDS             621..877
                     /locus_tag="IV356_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320124.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
BASE COUNT          378 a          164 c          198 g          348 t
ORIGIN      
        1 aacgtaatcc cttcgtatct gaatatgtta aacgacttgc aaaaggtatt tgtcaacttt
       61 gccaagaaaa agggccattt ataaaagacg gtgtacctta tttacattgt catcatatag
      121 aatatttgtc gcaaggtgga aaagatgtga ttgaaaactg tatcgcgtta tgtcccaatt
      181 gtcatgctag aattcatgaa cttgagttac ctgacgataa agaaaaattg ctgaagatcg
      241 ttgaaaaaag agaaaatagc ttttctaaaa taccgtaatt tatttttata ggacaaataa
      301 gctaatgtga gctatgcctt ctatataaga ctaagttcta ttataagtaa cgaagtaatt
      361 ctcgttcctt cctgtagtaa tattttttaa ataacctata ggcttcttca aaagtacatc
      421 ctccagtaaa ttctaagtac tggaggattc tttttctagt gttgctttac tcatgaaaaa
      481 gtagttggct acttcatcaa aatttctgaa cttttttaat gtataataaa gagctcgatc
      541 atttactaca aggatgctag ctcctacatt ttcacagttt tttagcaagt aaatttttct
      601 aaaatcacat caggaaatgc atgagattct ttaagaaagg caattatagg gctatgatta
      661 cggttcgtgt aagtgacgcc aaaaaagaat ggctttctta tatggctgaa ttttatggga
      721 ttactttatc tgaacttcta aaaaactatt cgatggaaca actagaagat gaatacaatc
      781 gtcaaacggc tgaaattgcc cataaacatt ggataagaag tgggaaaaca acagtattca
      841 tggaagaatc cttaatgaat ttggtgggct ggaatgacct gccgtttaaa attcacgccc
      901 gaaattcaga agcagctctg attggcaaat acgtgtattg gtagagatag aagataatca
      961 attcgttgtt accgctattc aagtagggca ccgaagaaat gtctatgatt aagagactgt
     1021 ttatttttac aaaaaaataa taactggaat ctagttaaaa ctcttgaagt gagagatttg
     1081 actagatt
//
LOCUS       DACDLM010000202         1064 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.211, whole genome shotgun sequence.
ACCESSION   DACDLM010000202 DACDLM010000000
VERSION     DACDLM010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1064
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.211"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(39..995)
                     /locus_tag="IV356_003011"
     CDS             complement(39..995)
                     /locus_tag="IV356_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016605.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          346 a          177 c          160 g          381 t
ORIGIN      
        1 ttttagaaaa agcagtcgga ctttctaaaa gaagttcact attcgatcct gtcgatgatt
       61 tcttcaggaa aatcgtctat ttgcttgtca attttgctgt ctttgtattt ctcttcttgg
      121 atagtcaaca aaatctttgt aagattcccc cagtctactg ctcttggcgg atcgagccaa
      181 accactactt gagatgcact ttcttcatat agattattcc tattcgtgat tataacatcc
      241 gggaactcag gctttcctgc ctctatcact tccgtgttca gattaatgta caagcttaaa
      301 tttttcttga taaattgatt ataggcagca ccataagaaa aatcgatgat gatctttact
      361 ggttcagaaa tcagttgaat gggtatgtga ttgatcaata ataataaata actgaaaaaa
      421 agaaaaaatt tatcttgaag caactctttg cgttttgacg ttagatcatt tatatactct
      481 atcaaatagc aataaaatgc tggatagttt tctctaaaaa aagaaacatc aagtggaaat
      541 tcatcagctt tattaatagt gtaatgcaaa agtttaaaat gtattttggt taactctctt
      601 cggatcaatt ggctcgtctc ttctcgcaac agattaaact gattttcaaa actttcaatg
      661 aatcgttcat tcaaccattc gattgtttca tcttcatttt ttctcaagta tttttgatcc
      721 aatttatcat gaagataaag ccaagagagt gtcttattga taaaaataac ggatttttct
      781 cctaatactc cttttaagtg gtaaaatcct atatccgaaa aaaatagcga ctgattgcta
      841 gcaatatcta aagaatcagc ttgttcagcc aacaggttga ttgctaaaaa gtggaataat
      901 ttcttttttt cataagcaga cagaggataa tactgtttta aatcttttaa cattttttct
      961 gtttttataa ttataggtag cgtatacaat tccacaaaac ttatctctgt tgagttaaaa
     1021 agattatata aaaaaagccg aatgttttta ggattccctg tcaa
//
LOCUS       DACDLM010000203         1042 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.212, whole genome shotgun sequence.
ACCESSION   DACDLM010000203 DACDLM010000000
VERSION     DACDLM010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1042
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.212"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..627
                     /locus_tag="IV356_003012"
     CDS             <1..627
                     /locus_tag="IV356_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAP9016606.1"
                     /translation="EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLI
                     AYMQKANADVEKELYANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFG
                     EDIYKIGMTRRLEPMDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVN
                     KINQRKEFFKVSLDEIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            699..>1042
                     /locus_tag="IV356_003013"
     CDS             699..>1042
                     /locus_tag="IV356_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016607.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQ"
BASE COUNT          462 a          120 c          175 g          285 t
ORIGIN      
        1 gaaaaagaac aacaaaaagc aataaaagaa cagatgatag aagaggaaaa agttcgtaga
       61 gaaattgatc gtgaaaagaa acgtattgat aaagaacaac gtcaattcaa ttctgaaatt
      121 tccaaattaa tcgcatatat gcaaaaagct aatgcagatg tggaaaaaga attatatgca
      181 aataaaattc aagaactgga agaaaaatta aaagaattag aagttatacg tgaaaatgta
      241 ttacaaagag aattaaatac tagagccggt tatgtgtatg taattagtaa tattgggtct
      301 tttggtgaag acatatataa aattggtatg actagaagat tagaacctat ggatagaata
      361 aaagaattga gtagtgcatc ggttccattt gaatttgacg ttcatgcgat gattttttca
      421 gaggacgctc cgtctttgga aactaaattg cataatcatt ttagaaaaca agaagttaat
      481 aaaattaatc aaagaaaaga atttttcaaa gtttcactag acgaaataga gaaagttgtt
      541 ttagaaaatt ataatggaac agtaacattt acaaaattag ctaaagctga acaatataga
      601 cgatctttag aattgtcaaa agattaaata tataaaaagc cttcgggctt tttcttttaa
      661 caattaatag gaacgtatat tcgaaaggaa tagaaataat gtggttagaa aaaataaatg
      721 acaaaaaatt taagtacacc gaacgttata cggatccctt aactgaaaaa aagagaaaag
      781 tgtccgttac tttatctagc aattcacgcc aagcttggaa tcaagctaac ttacttttga
      841 atgaaaaaat cgcagaaaaa ataaaacgaa atgaagaatt accactaact tttggagaat
      901 taaaaactaa atgggatgaa aaatacaagc caactgtaaa agaaagttcc tatcgaacaa
      961 ctcaggttta tctatcatta atttcaaaat atataaaaga tgatgtactt gtaaaaaacg
     1021 ttaatagtaa tcttatacaa ga
//
LOCUS       DACDLM010000204         1035 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.213, whole genome shotgun sequence.
ACCESSION   DACDLM010000204 DACDLM010000000
VERSION     DACDLM010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.213"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..>1035)
                     /locus_tag="IV356_003014"
     rRNA            complement(<1..>1035)
                     /locus_tag="IV356_003014"
                     /product="16S ribosomal RNA"
BASE COUNT          218 a          324 c          234 g          259 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatgcaccgc gggtccatcc atcagcgaca
     1021 cccgaaagcg ccttt
//
LOCUS       DACDLM010000205         1022 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.214, whole genome shotgun sequence.
ACCESSION   DACDLM010000205 DACDLM010000000
VERSION     DACDLM010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1022
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.214"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..876)
                     /locus_tag="IV356_003015"
     CDS             complement(<1..876)
                     /locus_tag="IV356_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP9016608.1"
                     /translation="MHKISVIVPAYNVENYLENCLESISNQTHSNIEIIVVDDGSPDR
                     SGEIAEEYKKKDMRLKVIHQVNGGLSAARNSGLDSATGDFVCFIDSDDWIEPDYLELL
                     YFGTQTYGADISVLKIKKISSLEQLKEHTIAERKWEIFDREQAMKNLFINNKIGYSAN
                     NKLFNRNLFDNIRFPLGKLMEDKATTYLLIDHSEKVAVNSSAKYHYYQSPKSILRGSF
                     NPRIFDSFEVHEDILVFIDKFYPELSINVRTRYVYEAIRMMMTMIKNNYTNKEDYLRS
                     INILQRFEKEVKIDPD"
BASE COUNT          327 a          177 c          122 g          396 t
ORIGIN      
        1 gtcgggatca attttcactt ctttttcaaa gcgttgtaaa atatttatag aacgtaaata
       61 atcttcttta ttggtatagt tatttttaat cattgtcatc atcatcctta ttgcttcata
      121 gacatagcga gttctaacat taattgataa ttccggataa aacttatcta tgaatactag
      181 tatatcttca tggacttcaa aagaatcaaa aattctagga ttgaagcttc ctctcagtat
      241 acttttaggg ctttggtaat agtgatattt agcagatgaa ttgacagcaa ctttttcgga
      301 atgatcgatc aacaaataag tagtagcctt atcttccatt aatttaccca gtgggaatct
      361 tatattatca aataaatttc tattgaataa tttattattt gcagaatagc caattttatt
      421 atttataaat aagtttttca ttgcttgttc tctatcaaat atttcccatt ttctctcagc
      481 aattgtatgt tcttttagtt gttctaaact tgaaatcttt tttattttta gcaccgagat
      541 atctgctcca taagtttgcg taccaaaata tagtaactca agatagtctg gttctatcca
      601 atcatcgctg tcaataaagc acacaaaatc tcctgttgca gaatcaagac cagaattcct
      661 agccgcactt aaaccaccat tcacttgatg tatcactttt aatcgcatat ctttcttttt
      721 atattcttct gcaatttccc cacttcgatc cggggaacca tcatcgacta ctattatttc
      781 aatatttgaa tgtgtctgat tggaaataga ttctaagcag ttttctaaat agttttctac
      841 gttatatgcg ggtactataa cactaatttt atgcactctc ttcacttcct aaaaatcatc
      901 ttttttattt ttacaaatgt atcattacca gtaacaattt tagtcttccg aagttaataa
      961 acataaaaaa taacatatcg aaaaaaactt tattttttta gaactttttt atataaaata
     1021 aa
//
LOCUS       DACDLM010000206         1013 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.215, whole genome shotgun sequence.
ACCESSION   DACDLM010000206 DACDLM010000000
VERSION     DACDLM010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1013
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.215"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..705
                     /locus_tag="IV356_003016"
     CDS             <1..705
                     /locus_tag="IV356_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP9016609.1"
                     /translation="DADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKV
                     DVSTAGNKKGIVVVTYPDGSKEEVEVTISVEDKKAPNKPQVDPITEGDQIVTGKTEPN
                     AEVTVTLPNGSQYHGTADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSN
                     EKDSEKAVSKDNKTDNQGSKQNKNRGKSSPQKQSSKAYPKTGEIDSNIFTISGGLILL
                     GTLGLLGYKNRKKENE"
     gene            839..>1013
                     /locus_tag="IV356_003017"
     CDS             839..>1013
                     /locus_tag="IV356_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP9016610.1"
                     /translation="MKKIVIIGSNHSGLAAARFLNLCDSNYEVILIDKKSEISYLECG
                     TSLFIKREVSNLED"
BASE COUNT          405 a          132 c          207 g          269 t
ORIGIN      
        1 gatgccgata aatacaatcc tgaaggacaa aaagtgacta cagacttaaa taaagagcca
       61 gacgcatctg agggaattaa gaacaaagaa gatctaccaa aaggaactac ttatacttgg
      121 aaagagaaag tagatgttag tacagctgga aacaaaaaag ggattgtagt agtaacatat
      181 ccagatggat ctaaagaaga agtagaggtt actatttctg tagaagataa aaaagcaccg
      241 aataaacctc aagttgatcc tattacagag ggtgaccaaa ttgttactgg taaaactgaa
      301 ccaaatgcag aggtgacagt tacattacca aacgggagtc aataccatgg gacagctgat
      361 aaaaatggta attttacagt taaagttcct aaattagagg caggaacaaa agtgatagta
      421 actgcaactg atgaatctgg taatactagt gaacctacta atgtagttgt ttcttcaaac
      481 gaaaaagaca gtgaaaaagc cgttagtaaa gataataaga ctgacaatca aggtagcaag
      541 caaaacaaaa atagaggcaa aagcagtcct caaaagcagt cctcaaaagc ttatcctaag
      601 acgggagaga ttgatagtaa tatctttact attagtggtg gtttaatcct gttaggaact
      661 ttagggttat tagggtataa aaatcgaaaa aaagagaatg aatagaaaat caatttctta
      721 aatcttctct gaaaagagga agaatctttt tcttcctctt tttgtttttt attttgggag
      781 ataggttgtt agttaaaaat gaagatactt ttcatagaag ggaaaagaat gtgattaagt
      841 gaaaaaaata gtaattattg gatcaaacca ttcggggcta gctgcagctc gatttctaaa
      901 cttatgtgat tcaaattatg aagttattct gatagataaa aaatcagaaa ttagttactt
      961 agaatgtggg acatcgttgt tcataaaaag agaagttagc aatttagaag atc
//
LOCUS       DACDLM010000207          985 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.216, whole genome shotgun sequence.
ACCESSION   DACDLM010000207 DACDLM010000000
VERSION     DACDLM010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..985
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.216"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            7..624
                     /locus_tag="IV356_003018"
     CDS             7..624
                     /locus_tag="IV356_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016611.1"
                     /translation="MGFQVLFGSLILTIVFLKWKTSNKKSMWSLVGIVLIIFTVTAAT
                     EANYSHKIQSYKGRLVMTKKDVTRYTSSRTGGLYDYAPLDALKYKDHLKKHEVKVGDR
                     WENASHKAYNSKIVYTVEDADEQNITLPVFNYWGTVVKVNGKKSTIENDNGLVSIKGT
                     GKRTIVEVSSTYPTTMILSLLISSITFIFLFTRYLIRCCGEMKID"
BASE COUNT          359 a          127 c          164 g          335 t
ORIGIN      
        1 agaaccttgg gttttcaagt gctttttggt tcattaatct taaccatagt gtttttaaag
       61 tggaaaacaa gcaacaaaaa aagtatgtgg agccttgtag gaatagttct tattattttt
      121 actgtgactg cagcaacaga agcaaattat tcgcataaaa ttcagtcgta taaaggtcgt
      181 ttagttatga ccaaaaaaga tgttacacgt tatacatcct caagaactgg aggcctatat
      241 gactatgcac cattagatgc attgaaatat aaagatcatt taaagaaaca tgaagtaaaa
      301 gttggtgatc ggtgggagaa tgcatctcat aaagcatata attccaaaat agtctataca
      361 gtagaagatg ccgatgagca aaatatcaca ttacctgtat tcaattattg gggaacagtt
      421 gtgaaagtaa atgggaaaaa gagcactata gaaaatgaca atggtttagt gtctattaaa
      481 ggtacgggga aaagaactat agttgaggtt tcatctacgt atccaactac gatgattcta
      541 tctttattaa ttagttcaat aacttttata ttcttattta cacgttattt aataagatgc
      601 tgcggtgaaa tgaaaataga ttagatagat attataaata tgttgattct attttcatag
      661 caatggagaa aatacattag caatatataa aagaaggtat caagagtcac agtgaattta
      721 ttccgaaaag tgaaaagagc aaatataaaa tttaatgaaa atatagaact aaataggaaa
      781 acgtagacgt aattttctac gttttccttt tcatatatat taaatattac ggaaaattat
      841 ataaactaat ttagtgtttt gtttgtaatt cctaattttg ctccactttt agataatttt
      901 taggtctatt taactcatca gacattctat gctcattttt ctccaaattt gtttcaactc
      961 tttcgtactt aattttgcgt atttg
//
LOCUS       DACDLM010000208          961 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.217, whole genome shotgun sequence.
ACCESSION   DACDLM010000208 DACDLM010000000
VERSION     DACDLM010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..961
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.217"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..134
                     /locus_tag="IV356_003019"
     CDS             <1..134
                     /locus_tag="IV356_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP9016612.1"
                     /translation="VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            complement(293..769)
                     /locus_tag="IV356_003020"
     CDS             complement(293..769)
                     /locus_tag="IV356_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAP9016613.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(782..>961)
                     /locus_tag="IV356_003021"
     CDS             complement(782..>961)
                     /locus_tag="IV356_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="phosphoenolpyruvate-dependent sugar
                     phosphotransferase system; catalyzes the phosphorylation
                     of incoming sugar substrates concomitant with their
                     translocation across the cell membrane; IIB is
                     phosphorylated by IIA and then transfers the phosphoryl
                     group to the sugar; IIC forms the translocation channel;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIBC"
                     /protein_id="HAP9016614.1"
                     /translation="ACATRLRVAVTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKA
                     DLLSQEINQILGKDN"
BASE COUNT          329 a          176 c          128 g          328 t
ORIGIN      
        1 aagtgaatca gacatttatt tccagtgtca gcaatcaacg taatcatatt ccaagaaaat
       61 cattgaatta cagaacacca atcgaaatat ttttgagcta tgtacaagaa gcattttatt
      121 ctagcttaat ttgacaaatc ataactttaa attacggatc atgatttggc atggggaatc
      181 attactaata aaataaaaaa atgaacagaa agaaaacagt tctttctgtt caccaacttc
      241 atttgacaaa tatcctattt agcttatttt atagcttttt atatacactt ttttaaaaag
      301 tgatttttcc acatgaattc ccatgagcaa ttcgaccatt atctattatt aaatcattga
      361 actgattttt ctccggaaaa acaactataa cagaagtatc tttaccagat tttattattt
      421 tgtcaaaatc cacatcaacc aacgaggttt caggagtaac ctcatcattt tcttgaacac
      481 aaatcgaaaa aggctctcct tgtaattcaa ctgtatcaat tccaatatga atcaaataat
      541 caatgcctga gttgcttttt atattaatag catgtttagt aggaaatata tttgttactc
      601 gaccagccaa tggagcataa atttttgaac catcaggtat gacggcaaaa ccatcaccta
      661 gtaatttttg tgaaaagaca ggatcattta cttctgtgat ggaaatgatt tttccggaac
      721 aaggtgcata aaaagtttct tgttttttct ttttgaaaat ttcaaacata ttaaaaacct
      781 cctaattatc ttttcctaat atttgattga tttcttgact taataagtca gctttccctc
      841 caaaaacagc ttggatgcca cccttcactt cgaagacagc agttgcacca gtgtctttta
      901 ttgtttgttt ttgaataatc tccccattcg taacagcaac acgcaaacga gttgcacaag
      961 c
//
LOCUS       DACDLM010000209          955 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.218, whole genome shotgun sequence.
ACCESSION   DACDLM010000209 DACDLM010000000
VERSION     DACDLM010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..955
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.218"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            28..>955
                     /locus_tag="IV356_003022"
     CDS             28..>955
                     /locus_tag="IV356_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP9016615.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDEFFIQSVASKRNNIPRKSLDYRTPLEVFLSY"
BASE COUNT          329 a          164 c          179 g          283 t
ORIGIN      
        1 ccaaagaatt ataaggagtg agtacaaatg acctataccc atcttacaac ggatgaactt
       61 gtaataatag agtcttattt caaaatgaat caatctgttg ctaaaactgc ccattgcttg
      121 aatcgttcaa gacaaacgat ccataaagta tatctgttct tcaagcaagg aaaatcagcc
      181 ttagaatatt atcaacagta taagaaaaac aaatcaaact gtggtagacg tccgcttgtt
      241 ttacccgagg aacaatcaga atatattcaa agaaaggttg ttcaaggatg gacacccgat
      301 gtgattgttg gtcgtgcagc gtttcctatt agttgttctg ctcgtaccat ttatcgtatg
      361 ttcaaaaagg ggctatttga ttcttctgac ttaccgatga aaggcaagcg taaaccgaat
      421 ggacatcaag aaagacgtgg aaaacaaact ttccgccgct ctattcatga acgtgaaaag
      481 gattatagcc aattctcaaa tgagtttggt caccttgaag gtgacactat cgtaggtctg
      541 aaacataaaa gtgctgtaat taccttagtt gaacgattat caaaagttat catcacattg
      601 aaaccgtgtg gtagacaagc gattgatatt gaaaaaaaat taaatcaatg gtttgaatct
      661 gtaccgaaaa acctattcaa atccatcact tttgattgtg gaaaggaatt ttcaaattgg
      721 aaacagatca gtaatgtcaa tgatattgcc atttatttcg ctgatccagg aacgccgtct
      781 caaagaggcc taaacgagaa ttctaacgga ttgttacgta gagatggttt attgaaatct
      841 atggatttca attcagtaga tgaatttttt attcaatctg tcgcatctaa acgaaataat
      901 attcctagaa aatcactgga ttatcgaaca cctttggaag tatttttgag ttacg
//
LOCUS       DACDLM010000210          943 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.219, whole genome shotgun sequence.
ACCESSION   DACDLM010000210 DACDLM010000000
VERSION     DACDLM010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.219"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            2..>943
                     /locus_tag="IV356_003023"
     rRNA            2..>943
                     /locus_tag="IV356_003023"
                     /product="23S ribosomal RNA"
BASE COUNT          293 a          187 c          274 g          189 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact agg
//
LOCUS       DACDLM010000211          909 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.220, whole genome shotgun sequence.
ACCESSION   DACDLM010000211 DACDLM010000000
VERSION     DACDLM010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..909
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.220"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            112..453
                     /locus_tag="IV356_003024"
                     /pseudo
     CDS             112..453
                     /locus_tag="IV356_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            complement(793..>909)
                     /locus_tag="IV356_003025"
     CDS             complement(793..>909)
                     /locus_tag="IV356_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAP9016616.1"
                     /translation="TIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
BASE COUNT          302 a          168 c          133 g          306 t
ORIGIN      
        1 atcaactgtt gccttggaac aaggatgtac aacaacattt ttctcgtaac taaaaacgcc
       61 aaacattccc gattctattc tataggtcgg gttatttgac gtacaggtac tgttctatgg
      121 ggcgcttacg aagaggcatt ggatcacatc gactttatga ctaggaaatg gaaaaagcag
      181 tatccaagag tcgtcaattt actcttgaat cctgccctat taacctttta taatttccct
      241 cacgccatca gacgaacaat ttattcgacg aacctgattg aaggctttaa taagcagcta
      301 aaacgatata ctcgaagaaa agaacaattc cctaatgaag aatctctaga gagattcttc
      361 atttctcaat ttaatcaata taaccaaaaa tttttaggta gaattcacaa gggatttaaa
      421 gaaattcagg atacattaga gtcgatgatt taactgtaat taacagaatg gattttccat
      481 ttacatataa ttcttgacgc taccataatc taaataacca tcatattcat ctactactta
      541 tataattgag ttttattaaa ctttttaagt ttctattcta tcaaatattt aaacaatctc
      601 tgcatccgaa aagactacct cgtatagttt tactaacaat atttttatta gcgtgttcaa
      661 atcctgattt cttgtatcaa ttattttctg ttcactttca ataagaaaaa agtctttact
      721 tccatggata ataataaggg ttctgttgca aagttttaaa taaagaataa aatcccttac
      781 ggtatctatg atttaagctg ggattcccaa taataccttg atttcagtac agaccgaaaa
      841 cccgaagaga gtgccttctt ttcgggtttt cttatataat cctcggatgg cttccatgcc
      901 tttaatcgt
//
LOCUS       DACDLM010000212          901 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.221, whole genome shotgun sequence.
ACCESSION   DACDLM010000212 DACDLM010000000
VERSION     DACDLM010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..901
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.221"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            167..868
                     /locus_tag="IV356_003026"
     CDS             167..868
                     /locus_tag="IV356_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAP9016617.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
BASE COUNT          326 a          158 c          147 g          270 t
ORIGIN      
        1 tcgcttcaaa acaaattatt caataccatt gtatattttt tacataataa caaattatat
       61 ttgtaaagta ttaaaacttg tttctaatgt tggtatgtta aaactttaca aattctttaa
      121 aaaaagtgac aataaatata gtgaacaata aggagaggac tttttaatgc gtgttaataa
      181 aatcgatttt cacttttcaa aactcagata tcaacctgat tttgaacatt tctcggatga
      241 agagttccaa cagatcaagg aacatactgt tcttcgttct tataaaaaag gacagatcct
      301 tttcgacgat ggtgatccca gacaacggtt gtatatcttg accaaaggac tcgttcgttt
      361 agaacgttat gatgaaagtg caacttatta ctactatgac tatgtgaata caaataacct
      421 ttttcctatg tcaggaatgt ttggagaaga gacctacact tatacagctc aagcgatgac
      481 tgatattgaa acattctacc ttcctgtttc ctactatgaa aaattagcac gaaaaaatcc
      541 cgaacagttg atctatatga tacaaaaaat ttctaaagta gttgaaatac atgaattgcg
      601 tatccaaatc ggattgacct ctagcgcctt tgaccgggta aaacaaaatt tattcatttt
      661 gaaagaagaa ttgggcgtac caacaaaaga tggtcatatc accattcctt atccgatcac
      721 cttaaaagaa ttagcagtga atagcggcac gacacgtgaa actgctggac aagtaatcaa
      781 acaactacgt gattccgggc tgttagatta tgacaaaaag cgttttactt tctgtaagac
      841 agctactact ccagctatga gagaataacg cgaacaaaaa taagcagtga ccctgataaa
      901 t
//
LOCUS       DACDLM010000213          888 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.222, whole genome shotgun sequence.
ACCESSION   DACDLM010000213 DACDLM010000000
VERSION     DACDLM010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..888
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.222"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..254)
                     /locus_tag="IV356_003027"
     CDS             complement(<1..254)
                     /locus_tag="IV356_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAP9016618.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSART"
     gene            complement(254..517)
                     /locus_tag="IV356_003028"
     CDS             complement(254..517)
                     /locus_tag="IV356_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAP9016619.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            751..>888
                     /locus_tag="IV356_003029"
     CDS             751..>888
                     /locus_tag="IV356_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAP9016620.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LK"
BASE COUNT          285 a          176 c          119 g          308 t
ORIGIN      
        1 gtccttgctg aataaatttc aaccacgtgt tcatcttcat ctaccttata aacaacccgg
       61 tgttgtctat tcaatcttct agaataccta ccttcatgtg taggttttaa cttctcaaat
      121 gattgggtag ggagataggg atcttccttt aaagtctgaa taaccttctc aaattgaggt
      181 ttcaaattag actgtttgat tttctttaaa tcagctttag ccgagttttt aatcatcaca
      241 gaatagttat tcattataag ttatcccaat caatttcatc aacattagta aatccactat
      301 catctttttc tcgcttacga acaacaccca aagtgcctat ttgctcaagt aatagcgttt
      361 ctttgattgc tttccaatca tccaaaccaa taagcaccgc attattttca ctgcgctcac
      421 taatgatttc aatttccgta tgattctcat ttacatcttt caacaactta taaaaatttt
      481 tccgtgctga gctaggattt aagactgttt ttgccatatc tactccccct ctaatttata
      541 tctccattct aacgtactta attaagtacg taaattcgat tgttttgttt aaattggagt
      601 accaaaacag cattgtaaag tgttatccgt ttcctttata cccgtggtgc tagttaattt
      661 tttcctagag gaaaatgtct aaacatgttg gtaaatcaac aaaaaaacgc atagagtagt
      721 ctcaaaactc ccaagaaatg aggactacat atgcgttcat caaaatatac tgaacattat
      781 acagatactt ttataacatt caaggaaatt atgagaactg tttctaacat ataccacaat
      841 tgtgtaccag ataagattaa aaaccgaaga aatactgatc aactgaag
//
LOCUS       DACDLM010000214          883 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.223, whole genome shotgun sequence.
ACCESSION   DACDLM010000214 DACDLM010000000
VERSION     DACDLM010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..883
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.223"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..881
                     /locus_tag="IV356_003030"
     CDS             <1..881
                     /locus_tag="IV356_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HAP9016621.1"
                     /translation="DSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVK
                     KLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTC
                     QIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLF
                     NGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENN
                     IIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIKL
                     KLNGLSPVEYRKQSIK"
BASE COUNT          382 a          114 c          143 g          244 t
ORIGIN      
        1 ttgattcaag aacaagattt gagcaagaag aaatcaaggt taaaacaatc cttcagctca
       61 aaaaagaatt taaattgaat ctattacttt caattgcaca attagcgaag tcaacttatt
      121 attactgggt aaaaaaatta gataagccag ataaatatag caagataaag caagaaatta
      181 cagcgattgt aaaagaatca agaaactctt atggttatcg tagagtcact ttagcgttaa
      241 agatgaaagg atatacaatc aatcataaaa cagttagaaa attaatgtcc caaatgggac
      301 ttacctgtca aatccgaata aagcgatata aatcttataa aggaacagta ggaaaaattg
      361 ccaagaatgt gttaaaacga aatttttcag tagatacacc caataaaaaa tgggtgacag
      421 acgtcactga attcaagata aaaggaagaa aaatctatct atctcctata cttgatttat
      481 ttaacggaga aataattagt tatagtatat caactagtcc aacatataaa ctgattgaag
      541 aaatgcttca acaagcaatt aaaaaaaagg gaactgaggg ttcactgatt ctacattcag
      601 atcaaggatg gcagtatcag atgccacaat atcaaaaaaa attaaaagag aataacatta
      661 ttcaaagcat gtctagaaaa ggaaattgct tagataattc tgtaatagaa aatttttttg
      721 gtgtgcttaa atcagagttt ttttatcgag aaaaattccg atcaattgag atatttcaaa
      781 gtaaattaaa tgagtatatt aggtggtata ataacaaaag gataaaacta aagttaaatg
      841 gactatctcc agtagaatat cggaaacagt ccattaaata gtt
//
LOCUS       DACDLM010000215          865 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.225, whole genome shotgun sequence.
ACCESSION   DACDLM010000215 DACDLM010000000
VERSION     DACDLM010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..865
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.225"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            1..865
                     /locus_tag="IV356_003031"
                     /pseudo
     CDS             1..865
                     /locus_tag="IV356_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
BASE COUNT          286 a          174 c          174 g          231 t
ORIGIN      
        1 gaccgtacgg tcaagaccga gtacggggaa cttcatctcc agattccgcg cgaccgcaac
       61 ggcgagttca agcaacagac tgttcctgct tatagacgga cgaatgatac cttagaggag
      121 accgtcattc acctcttccg aaaaggtatt accatgtcgg aaatcgcaga cttgattgag
      181 aaaatgtatg ggcatcacta cacgccccaa accatgtcca acatgactaa agtgctgact
      241 gaagaagtaa atgcatttaa agttagaact ctaaatgata agtatgtcgc tattttcatg
      301 gatgctactt atattccttt aaaacggcaa accgtctcca aagaagcaat ctatattgcc
      361 attggtatac gagaagacgg cactaaagaa gtactaagtt atgcgattgc tccgactgaa
      421 tcgacctacg tttggaatga gttgttacag gacatttact ccagaggggt tcatgatgtc
      481 ttactgttta ttaccgatgg cttaaaaggc atgaaagata cgattcacca gatttatcct
      541 aaagctaaat accaacattg ctgtgttcac gtttcccgta atattgctca taaagtacgt
      601 gtcaaagatc gaaaagaaat ctgtgatgat tttaaggctg tttatcaagc tagctcaaag
      661 gaagaggcaa ataccttttt agggagtatg attgagaagt agcaaaaaac ttatcctaaa
      721 gtgacgcagt cactgataaa aaatcaagat ttattgactt tttatgagtt tccgcctggt
      781 atccgccgaa gcatttactc aactaattta atcgaatctt tcaagaaaca aatcaagaaa
      841 tacagccgca gaaaagagca gtttc
//
LOCUS       DACDLM010000216          845 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.226, whole genome shotgun sequence.
ACCESSION   DACDLM010000216 DACDLM010000000
VERSION     DACDLM010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 845)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 845)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..845
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.226"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..>845)
                     /locus_tag="IV356_003032"
     CDS             complement(<1..>845)
                     /locus_tag="IV356_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAP9016622.1"
                     /translation="KKIICVKKDGTRFSQEYDKLILATGSKQIMLDVPGNNLANIFSI
                     KNFPNAKEIFKALDDNTIKKVGIIGAGYIGVEIAEAIRKRGKEVYLFDVADRVLSTYY
                     DRSFSDKVEEILSKNGIHLCLSESPKKYLGRKKIEKIVTTSGTQYSMDMVVQAIGFLS
                     NSPIGKKELLRDVSGAYLTNEYQQTNIKDIYAIGDCATTFFTSINRSSVDFSISNALR
                     TAYIATQHIDNQDFTPSGSQFTNGFSIFNYNFYAAGLNLKTARLLSESIDYIEIEDFI
                     RPVFL"
BASE COUNT          275 a          145 c          107 g          318 t
ORIGIN      
        1 tcaaaaaaac aggtctaatg aaatcttcta tttctatata atctatagac tcacttaata
       61 atcgtgctgt ttttaaattc aaacctgctg cgtaaaaatt gtaattaaat atagaaaagc
      121 catttgtaaa ttgggaacca gaaggtgtaa aatcttgatt gtcaatatgt tgagttgcaa
      181 tataagctgt tcttagagca ttagaaatag aaaaatcaac actacttcta ttaatggacg
      241 taaaaaaagt tgtagcacaa tccccaatag catatatatc ttttatattt gtttgctggt
      301 attcattagt tagatatgct ccactaacat ctctcaagag ttcctttttg ccaattggac
      361 tattagatag aaatcctata gcttgtacga ccatatccat agagtattgg gtaccacttg
      421 tagtgactat tttttcaatc ttttttcttc ctaaatattt tttaggactt tctgatagac
      481 aaagatgtat tccatttttt gatagtattt cttcaacttt atctgaaaaa ctacggtcgt
      541 aataagtcga caacactcta tctgcaacat cgaaaagata tacttctttc cctctttttc
      601 ttatggcttc agcaatttca actccaatat atcctgctcc aataattcct acttttttaa
      661 tagtattatc atctaaagct ttaaaaatct ctttagcatt tggaaaattc tttatcgaaa
      721 aaatattagc taaattattc cccggtacat ctaacataat ttgctttgaa cctgtagcta
      781 gtataagttt gtcatattct tgggaaaatc ttgtgccatc tttttttaca caaataatct
      841 tttta
//
LOCUS       DACDLM010000217          765 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.229, whole genome shotgun sequence.
ACCESSION   DACDLM010000217 DACDLM010000000
VERSION     DACDLM010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..765
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.229"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(597..740)
                     /locus_tag="IV356_003033"
     CDS             complement(597..740)
                     /locus_tag="IV356_003033"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016623.1"
                     /translation="MEKEAFDLHVLGTPPAFVLSQDQTLIKSSNNLAIVKLNLFASIL
                     LAC"
     gene            659..>765
                     /locus_tag="IV356_003034"
     rRNA            659..>765
                     /locus_tag="IV356_003034"
                     /product="16S ribosomal RNA"
BASE COUNT          315 a          124 c          134 g          192 t
ORIGIN      
        1 aattccttag gcagcttttg ctgtgtagaa aggaataaat aataacgaaa gttcaaaagc
       61 taatgccgac tattctagac attaaagaag acgaaaacga acgataaaga aagaaaagtt
      121 atgaataatc gtttattgaa aaaaacttga aaaaatacaa aaaattcgtt gaccaagcta
      181 aatttagttg gtatattatt acttgtccaa aagacagaag aaaatattta ttcaaaaaca
      241 taacaaaaaa gttattgaca tgttactaac gacatgataa gataactgag tcgttaaaaa
      301 agaaccactt gcgaagcttg attctatcga aaaaaacttc aaaaaagttc ttgacaaata
      361 acaaacgata agttatgata aatgagttgc cgaaagattt cgaaaaacga aatcgaaaaa
      421 aacttttaaa aaagagttga caatcgcttg tctctctgat atgatataaa agttgctacg
      481 gcagccaaaa atgaatcggg aaacactctc gatgaagtag acctttgaaa actgaacaaa
      541 gtaagacaaa ccaaatgtgt agggcgtctt gattcaattc aagacaacaa acatttttaa
      601 caagcaagca atatgctagc aaacaaattg agcttaacaa tcgcaagatt gttcgaactt
      661 tttatgagag tttgatcctg gctcaggacg aacgctggcg gcgtgcctaa tacatgcaag
      721 tcgaacgctt ctttttccac cggagcttgc tccaccggaa aaaga
//
LOCUS       DACDLM010000218          705 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.230, whole genome shotgun sequence.
ACCESSION   DACDLM010000218 DACDLM010000000
VERSION     DACDLM010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..705
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.230"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..461)
                     /locus_tag="IV356_003035"
     CDS             complement(<1..461)
                     /locus_tag="IV356_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP9016624.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYS"
BASE COUNT          224 a          128 c          101 g          252 t
ORIGIN      
        1 ttactatata cagaaataga aggtgggaca tctaaataga tgacgtcaaa ctcatcaaat
       61 aatggttcta gcttttcttt catatatttg aattgggata atgaatcatt atattggtct
      121 ttgatccaat catcatacat ttcaaaggac atgtctgctg gaagtatata gaggttattg
      181 attactttat agacagcctc tttaggtgga agattgttta tcaacacgtc agtcacagta
      241 ttttcgtaaa caatcggttc accttctccg cctccttctt cgttagtgaa gttcatatgc
      301 gttaagttca tcacatcaga agtatttcct tgcatatcca agtcaattat caaggttctt
      361 tttccttcat taactgctga ttcaaaccct aacatttgcg cgcacgtact tttacctacg
      421 ccacctttaa aattaccgat tacatatttc ttcgctacca cgttcctacc tcttttcttt
      481 tagcaatatt catttgatac tattataaca tatttatttt tagttactac caaaaaaaga
      541 tatatatgta ctaccttata attaataagt aaaaggtagt acataaataa ggaaaagctg
      601 aaatatattg atttatagct ttcctcaaag taatgacgtt atttaattta tcgagaagca
      661 gagaatactc gcgactttag tcatgtagac gaatcagatt ttcga
//
LOCUS       DACDLM010000219          692 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.231, whole genome shotgun sequence.
ACCESSION   DACDLM010000219 DACDLM010000000
VERSION     DACDLM010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..692
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.231"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
BASE COUNT          242 a          119 c           82 g          249 t
ORIGIN      
        1 attgacgctc cctccaaatt acttcatcaa aacattgata taatttttat tatatcagta
       61 tttattcttg atacataaat gagaaaataa atactttaaa tctattgact acaagtagtc
      121 attaagtctt cataagatgt acaatatgac attaaaaaaa taaaagctta cgaccatccg
      181 ttaaatctga cactaaataa tggactgctt tcttttgtat tagcaggtta cgttgactat
      241 gaatattcac cagattattt ggagaaacct cttcaacacg agaacaatga tattaatttt
      301 agatttgtct acgagtcaaa aagtaaaaca tggttagttg atcaattaag cacgataaac
      361 acaagcttcc atgaattacc taaacctgaa aatgaagttg agatggtcat taaaatcttc
      421 taaaaaagaa gcgttgaagg ggaaatattc ctttcaacgc tcttttttat atgcttagaa
      481 acataaataa attgtatact ttctttttag cccctattac ttttcacgaa aaatatcttt
      541 ttttcgacgc tagcgtttct ctacttctaa tactgtacac agtttttgta ttattgaaaa
      601 attactcatt atttagcatt aatccacatc gttttatcaa tcgaccttca tactaaacta
      661 ctttaaagtc atcttccttc tcgtttttca tt
//
LOCUS       DACDLM010000220          688 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.232, whole genome shotgun sequence.
ACCESSION   DACDLM010000220 DACDLM010000000
VERSION     DACDLM010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..688
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.232"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..298
                     /locus_tag="IV356_003036"
     CDS             <1..298
                     /locus_tag="IV356_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021424053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase family
                     protein"
                     /protein_id="HAP9016625.1"
                     /translation="LDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDI
                     LRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
     gene            complement(428..>688)
                     /locus_tag="IV356_003037"
     CDS             complement(428..>688)
                     /locus_tag="IV356_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015077585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP9016626.1"
                     /translation="PKYSKACASLDDGFEDAFQYTVQGNSHNRLKSTNLIERLNQEVR
                     RREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
BASE COUNT          258 a           70 c          126 g          234 t
ORIGIN      
        1 gttagatggc aataatagat taactggaat aattgatttt ggagattctg gaattataga
       61 tgaatattgt gattttatat acttacttga agatagtgaa gaagaaatag gaacaaattt
      121 tggagaagat atattaagaa tgtatggaaa tatagatatt gagaaagcaa aagaatatca
      181 agatatagtt gaagaatatt atcctattga aactattgtt tatggaatta aaaatattaa
      241 acaggaattt atcgaaaatg gtagaaaaga aatttataaa aggacttata aagattgatt
      301 atataatata tgaaaagcta ttataaaaga cattagtatt aaatagttta aaaaaatgaa
      361 aaataataaa ggaagtgagt caattccaga ctcctgtgta aaatgctata caatgttttt
      421 accatttcta cttatcaaaa ttgatgtatt ttcttgaaga ataaatccat tcatcatgta
      481 ggtccataag aacggctcca attaagcgat tggctgatgt ttgattgggg aagatgcgaa
      541 taatcttttc tcttctgcgt acttcttgat tcagtcgttc aattagattg gtactcttta
      601 gtcgattgtg ggaatttcct tgtacggtat attgaaaggc gtcttcgaat ccatcatcca
      661 atgatgcgca agcttttgaa tattttgg
//
LOCUS       DACDLM010000221          688 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.233, whole genome shotgun sequence.
ACCESSION   DACDLM010000221 DACDLM010000000
VERSION     DACDLM010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..688
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.233"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..338)
                     /locus_tag="IV356_003038"
     CDS             complement(<1..338)
                     /locus_tag="IV356_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021424053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase APH(3')"
                     /protein_id="HAP9016627.1"
                     /translation="MKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTN
                     KKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTM
                     SEEEQNLLKR"
BASE COUNT          222 a          110 c           72 g          284 t
ORIGIN      
        1 tctcgtttta acaaattttg ttcttcttct gacatagtag aataaatttc tggtgttaaa
       61 aaagttcctt taatttcttt ataacctagt atagataatt catcactaat atacgaatat
      121 tcaatattag gaatttttac attagtttct aaatttgtat ttaaaaaatt atatattgct
      181 ttttcttttg cataaccttt tttcttatta gtactaaatt ttgttttaaa aatgtattca
      241 ttattaacta aatatgccac actatcataa ccactaccga ttatttcaat actatctact
      301 ttgaaattat caaagtaatg ctcaattaaa tatttcattg ccttaacatt tgtggcatta
      361 tcatcatatc tatattccat taaataacaa tcttcttttt tgccctcgtg taattcatgt
      421 tctggcaaat cttcaataat tctaaaacca gatttttggt atgcccttat tgctcttgga
      481 ttatttttat gagggtctaa aataactgca ttagcatttc tttctttttt caaaaattca
      541 aaaatcaatt taatatatct tgtacggttc tgttgcaaag ttttaaataa agaataaaat
      601 cccttacggt atctatgatt taagctggga ttcccaataa taccttgatt tcagtacaga
      661 ccgaaaaccc gaagagagtg ccttcttt
//
LOCUS       DACDLM010000222          664 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.234, whole genome shotgun sequence.
ACCESSION   DACDLM010000222 DACDLM010000000
VERSION     DACDLM010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.234"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..525
                     /gene="tnpB"
                     /locus_tag="IV356_003039"
     CDS             <1..525
                     /gene="tnpB"
                     /locus_tag="IV356_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element transposase accessory
                     protein TnpB"
                     /protein_id="HAP9016628.1"
                     /translation="KMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLH
                     EKVMNQRTDFLNKLSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQ
                     YKADWYGRKIIKVDKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASIN
                     ILTEGLRLHSMGLA"
BASE COUNT          246 a          106 c          129 g          183 t
ORIGIN      
        1 aaaatggaaa agaaactaaa gcgtgaacaa cgcaaattgt ctaggcgtgc tttattggct
       61 aaaaataaag gtaccaatct atttgaagct aaaaattatc aaaaacaaaa acgcaaagta
      121 gctagattgc atgaaaaagt aatgaatcaa cgtactgatt ttctgaataa gttgagtaca
      181 gaaatgatca aaaatcacga tattatctgt attgaagact taaacacaaa aggtatgttg
      241 cgaaatcata aattagctaa aagtatttct gatgtttctt ggtcaaagtt tgtgactaaa
      301 ttacaataca aggctgactg gtatggacga aaaatcatca aagtagataa atggtttccg
      361 tctagtcaga tttgttcaga gtgcggacat aaagatggca agaaatctct tgaaattcga
      421 gaatggactt gtcctgtttg tcatactcat catgatcgtg atatcaatgc tagtatcaat
      481 attctgaccg aaggtctaag actacattct atgggattgg cttagatcca atcatcaaga
      541 accgtaggaa ctacggggat agcttggtaa ataagagaca ccgctgttag taaagaaata
      601 cgctatcaag tatgctctat tcccaagaag ctcccacttc aagcgttaag aaccgtcagg
      661 ttta
//
LOCUS       DACDLM010000223          645 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.235, whole genome shotgun sequence.
ACCESSION   DACDLM010000223 DACDLM010000000
VERSION     DACDLM010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..645
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.235"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..>645
                     /locus_tag="IV356_003040"
     CDS             <1..>645
                     /locus_tag="IV356_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAP9016629.1"
                     /translation="SFQVKERQHQESLQLYQINEEYYHHLEEFKHDYKSLLFSLKITL
                     QENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRGVFLKFLEKAESEKIPIQV
                     VIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITINLLEEKEGSRFSIANKAN
                     PTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELKIEFSKQNHYFFVEM"
BASE COUNT          242 a          103 c          115 g          185 t
ORIGIN      
        1 tcagtttcca agtaaaagaa agacaacatc aggaatcgct tcaactgtat caaataaatg
       61 aagaatatta ccatcatcta gaggaattca aacatgatta taaaagtcta ctgttttcat
      121 taaaaattac tcttcaggaa aataaaaaag aaacgttgga atttttagaa atattagaag
      181 atcattctgc agctattttt gaaaaaccgc aaatacaaca gctaacaaat attgtatccc
      241 cagctgtcag gggtgtcttt ttaaaatttc tagaaaaagc agaatcggag aaaatcccga
      301 tccaagtagt tattcctgtc gaagtgaaaa caatcccgat tgatctggtt gtttttattc
      361 gctgtttatc tatttttatt tctaacgcat tcgatcatcg tgtagccgat cagagtccga
      421 ttacgatcaa tctgctggaa gaaaaagagg gatcacgttt tagtatagcg aacaaggcaa
      481 atccaacgaa tttgacgcta tcggagatgg tcaaaagagg aaaaacctct aaaaaaaatg
      541 gcgggttagg tctatacagt gcgaaaaaaa tgttggatgt ttacgaaaat gcagaactaa
      601 aaatcgaatt ttcaaaacag aatcactatt tttttgtaga aatgt
//
LOCUS       DACDLM010000224          627 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.236, whole genome shotgun sequence.
ACCESSION   DACDLM010000224 DACDLM010000000
VERSION     DACDLM010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..627
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.236"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            330..>627
                     /locus_tag="IV356_003041"
     CDS             330..>627
                     /locus_tag="IV356_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP9016630.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFP"
BASE COUNT          230 a           69 c          104 g          224 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaa
//
LOCUS       DACDLM010000225          556 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.237, whole genome shotgun sequence.
ACCESSION   DACDLM010000225 DACDLM010000000
VERSION     DACDLM010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..556
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.237"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(152..346)
                     /locus_tag="IV356_003042"
     CDS             complement(152..346)
                     /locus_tag="IV356_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016631.1"
                     /translation="MVHSTIGVVVEKSRDNLVFVTEIQTGRSFVVTDKAAKAYQSSDI
                     LTLNLTTKTFVDATEDYPFV"
BASE COUNT          171 a          113 c           88 g          184 t
ORIGIN      
        1 tgtgatagag aaataacaat ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat
       61 ttgattttga tcgggtctag tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc
      121 ttaaatttca tcttgactta tcaccattag actaaacaaa tggataatct tctgtcgcat
      181 cgacgaacgt cttcgtagtc agatttaacg ttaaaatatc gctactttga taagcttttg
      241 ccgctttgtc tgtgacgaca aaagatctgc ctgtttgaat ttctgtcaca aaaacgagat
      301 tgtctctgct tttttcaaca acaactccaa tcgttgaatg aaccatttct gcttcctccc
      361 ttctctttct tttgatataa tgtagtcgca aatcgcacca ctcaatgagt tggcggaaaa
      421 caattcattg aaaaaaagag tcctggacaa tcacgttcag gactctttta cttcttttat
      481 tcacttaaca actaacactc tgtgagtgaa atggactctt caatgtgatg ttaggatgat
      541 ttcatggaca cgattt
//
LOCUS       DACDLM010000226          547 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.238, whole genome shotgun sequence.
ACCESSION   DACDLM010000226 DACDLM010000000
VERSION     DACDLM010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..547
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.238"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            131..418
                     /locus_tag="IV356_003043"
     CDS             131..418
                     /locus_tag="IV356_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016632.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT          196 a           87 c           99 g          165 t
ORIGIN      
        1 ctttttttgt gaaaagtaca attagttgtc tttcttcgaa ttttttgtca caataagcag
       61 caaagataaa gctgttacat aaaagaacaa gcagctttat ttgattttga aaagaaaggt
      121 gagaaagaag atgaataaag aatattttgt ccaacaagat gcatttttag aagattataa
      181 aagtgcttcg aagaaattaa cgatcaatat tgatgagttg gcagatcaag tactctctca
      241 gttgaatgaa acgcaagagg aatattacac gatgccagca aatgacgcca aagataatgt
      301 ttctcatcgt tttcctttca gtagacgcat ctactcagat gaaaatgacg gcacattgaa
      361 tacagagtac acatatgaag gtcagccata tgtgctagaa actgatgatg atctttaaag
      421 acagtttttg aaaaggccgc tcatccttaa gtgatgacaa aaaatcatca caattaccga
      481 tgactgtctc tttactatct tttaatcaga aaaaggggtt atgacaagct ttgtcaaccc
      541 ctttttt
//
LOCUS       DACDLM010000227          528 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.240, whole genome shotgun sequence.
ACCESSION   DACDLM010000227 DACDLM010000000
VERSION     DACDLM010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.240"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(5..90)
                     /locus_tag="IV356_003044"
     tRNA            complement(5..90)
                     /locus_tag="IV356_003044"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(54..56),aa:Leu,seq:taa)
     gene            complement(107..178)
                     /locus_tag="IV356_003045"
     tRNA            complement(107..178)
                     /locus_tag="IV356_003045"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(144..146),aa:Gly,seq:gcc)
     gene            complement(190..262)
                     /locus_tag="IV356_003046"
     tRNA            complement(190..262)
                     /locus_tag="IV356_003046"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(227..229),aa:Thr,seq:tgt)
     gene            complement(280..361)
                     /locus_tag="IV356_003047"
     tRNA            complement(280..361)
                     /locus_tag="IV356_003047"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(325..327),aa:Leu,seq:tag)
     gene            complement(369..441)
                     /locus_tag="IV356_003048"
     tRNA            complement(369..441)
                     /locus_tag="IV356_003048"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(406..408),aa:Lys,seq:ttt)
     gene            complement(445..517)
                     /locus_tag="IV356_003049"
     tRNA            complement(445..517)
                     /locus_tag="IV356_003049"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(482..484),aa:Val,seq:tac)
BASE COUNT          135 a          152 c          128 g          113 t
ORIGIN      
        1 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
       61 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      121 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      181 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      241 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      301 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      361 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      421 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      481 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactt
//
LOCUS       DACDLM010000228          526 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.241, whole genome shotgun sequence.
ACCESSION   DACDLM010000228 DACDLM010000000
VERSION     DACDLM010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..526
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.241"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..354
                     /locus_tag="IV356_003050"
     CDS             <1..354
                     /locus_tag="IV356_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAP9016633.1"
                     /translation="TQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVD
                     QEMYKQAQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISI
                     LKELEEHENWYAEVE"
BASE COUNT          209 a           75 c          115 g          127 t
ORIGIN      
        1 acccaagtaa aatcgatgag aaatgcgatg caatatcttg agtatatgga cttttttgtg
       61 aaagaatttg atacaaattt atatgttgct ggtgttattc ctttcatgtt ggaaagcggt
      121 gacgcagtag atcaggaaat gtataaacaa gcccaagaga tttatgggga acatttgatt
      181 aaaaatgttg tactcaaaaa tgcgcgctta aaacgatacg acggatcagg tattacgatg
      241 gagaagacaa agaaaggtct cttaaaacaa tgggatcgca aaagccacga attatttatc
      301 agtattttga aagaattgga agaacacgag aattggtatg cggaggtgga gtaattggct
      361 gacatcaaag gacttgatat ttttgggaac aacaaaggac tcgccaaaat aaaaaaagaa
      421 gcagaagcaa agaaaaagca gcaagcaatt acaccatctg aaaataagca attagaagtg
      481 caccaagttc aagaaataaa aacttcctcc aatgttgaaa gacaga
//
LOCUS       DACDLM010000229          514 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.242, whole genome shotgun sequence.
ACCESSION   DACDLM010000229 DACDLM010000000
VERSION     DACDLM010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.242"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..132)
                     /locus_tag="IV356_003051"
     CDS             complement(<1..132)
                     /locus_tag="IV356_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAP9016634.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          186 a           94 c           92 g          142 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactattag acaa
//
LOCUS       DACDLM010000230          489 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.243, whole genome shotgun sequence.
ACCESSION   DACDLM010000230 DACDLM010000000
VERSION     DACDLM010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.243"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            13..>489
                     /locus_tag="IV356_003052"
     CDS             13..>489
                     /locus_tag="IV356_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HAP9016635.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVA"
BASE COUNT          178 a           90 c           82 g          139 t
ORIGIN      
        1 gaggacttcc ctatgaatga ttttactaca gaaattgtgc aaactctagt cactaaaggc
       61 gatttaaatg aattattccg ttcgcactta gaaaaagcga taaacacact cctacggact
      121 gaattaacgg cttttttaga ttacgaaaaa tatgatcgca ctggttttaa ttcaggtaat
      181 tcgagaaacg gttcttactt tcgatcaatc aaaaccgaat atggtgaatt aacattggaa
      241 atacctagag atcgtaatgg tgagtttaaa caacaaactt taccagccta caaaagaaca
      301 aacgatacat tggaaaccac tattatccat ttattcgaaa aaggtgttac gatgtctgaa
      361 attgctgatt tgatcgaaaa aatgtacggt catcactata ctccacaaac catgtccaac
      421 atgactaaag ttctgactga agaagtaaat gcctttaaat ccagagcctt aaatgataag
      481 tatgtcgct
//
LOCUS       DACDLM010000231          486 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.244, whole genome shotgun sequence.
ACCESSION   DACDLM010000231 DACDLM010000000
VERSION     DACDLM010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.244"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..>486)
                     /locus_tag="IV356_003053"
     CDS             complement(<1..>486)
                     /locus_tag="IV356_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP9016636.1"
                     /translation="LYDEYFDCYICPQDQMLAFSTVTREGYREYKSNPKECVNCPLLN
                     QCTISKNHQRVITRHVWGDLMDEVEHLRLTDLNKSIYKKRKQTIERIFADAKEKHGMR
                     WTKYRGLEKVATHTMLVFAAMNLKKLATWLWKGKEPLFFCSKIRNEVDKKLFQARVTS
                     L"
BASE COUNT          127 a          107 c           84 g          168 t
ORIGIN      
        1 tccaaactcg taactcgagc ttggaacagc tttttatcta cttcgtttcg aatttttgaa
       61 caaaaaaata aaggctcctt gcctttccat agccaggtgg ctaatttctt taaattcatt
      121 gcagcaaaca ctagcatcgt atgcgtcgcg actttttcca agcctcgata cttggtccaa
      181 cgcatcccat gcttttcttt tgcatccgca aatattcgtt caatcgtttg tttccgtttt
      241 ttgtaaattg atttattcag atctgttagg cgaagatgtt ccacttcatc catcagatct
      301 ccccaaacat gtctcgtgat gactcgttga tgatttttac ttatggtaca ttggtttagc
      361 agaggacagt tcacacattc ttttggattg gatttgtatt ctcggtaccc ttctcgagta
      421 accgttgaaa aagcgagcat ttgatcttgc ggacaaatat aacaatcaaa atactcgtca
      481 tagaga
//
LOCUS       DACDLM010000232          439 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.248, whole genome shotgun sequence.
ACCESSION   DACDLM010000232 DACDLM010000000
VERSION     DACDLM010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.248"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            93..422
                     /locus_tag="IV356_003054"
     CDS             93..422
                     /locus_tag="IV356_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAP9016637.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
BASE COUNT          169 a           52 c           79 g          139 t
ORIGIN      
        1 ttacgagtca cagtaattac ttgtaaatac attatctcgt ggtataatgt atttactaag
       61 taattacata ctgttagaaa tgagggattt aaatgattac aaaaacaaga aaacaaggca
      121 attcaatcat gttgacagta cctaaagatt ttaatgttcc taatggagtc gaagttgaag
      181 caaagttggt agagaatggt attctttatg aatttgttga accacaaaaa gaattttatg
      241 attttagcga agatattttg tctgatataa ttgcagaagg ctacgataaa gatgagattc
      301 ttgtagaatt taagaataga aaaaacaaaa tgcattcttc ctttagagat attgctgaag
      361 atacacttac taattctaaa gtaatgacta aagaggagtt ggcaacagaa attggcttat
      421 gaaatcgttc cttcaaaac
//
LOCUS       DACDLM010000233          430 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.249, whole genome shotgun sequence.
ACCESSION   DACDLM010000233 DACDLM010000000
VERSION     DACDLM010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.249"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..>430
                     /locus_tag="IV356_003055"
     CDS             <1..>430
                     /locus_tag="IV356_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAP9016638.1"
                     /translation="QRATYRAVCSVLFPNGDFPSRSRFTRLSSNLAYTIKIIRYFFIK
                     KLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYFYGLKIHMIVTKT
                     GFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHK"
BASE COUNT          145 a           81 c           74 g          130 t
ORIGIN      
        1 caaagagcca cgtatagagc ggtttgttcc gtcttatttc ctaatggtga ctttcctagt
       61 aggagtcgat tcactcgctt aagttcaaac ttagcttaca ctatcaagat tattcgatac
      121 tttttcatca agaagctcac caaaggtgaa ctagtcggaa ttatagatag ttttcctagt
      181 ccattatgta aaccagttag aaatagacaa gcaaaactat tgaatcaaat agccaaagtt
      241 ggctataact caacaaaaaa atcttatttt tatggtctta aaattcatat gatcgttact
      301 aagactggct ttccgattac ttactcaatc acgaatccag gtgtccatga cgtgaaagtg
      361 ttagagactt tatcggaaga agcgaatctt cccaatatcc taggggacaa aggatatatt
      421 agccataaaa
//
LOCUS       DACDLM010000234          422 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.250, whole genome shotgun sequence.
ACCESSION   DACDLM010000234 DACDLM010000000
VERSION     DACDLM010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.250"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..>422
                     /locus_tag="IV356_003056"
     CDS             <1..>422
                     /locus_tag="IV356_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP9016639.1"
                     /translation="FVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIYNYHGW
                     EGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEEGGASS
                     LESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAEN"
BASE COUNT          166 a           55 c           84 g          117 t
ORIGIN      
        1 atttgttttt aagaaaaaag tagtttcaga ctatttaaat aacgaaggcg gctacaaata
       61 tcttgcacat aaatatcaaa taaatcgtac actggttaga cattgggtaa ggatttataa
      121 ctatcatggt tgggaaggct tggttggagg tggcaaaagc tacactacaa aatttaaact
      181 tgatgttata gaatatatgg aaacaaatgg tctttctatc caagaaactg ctaaaaaatt
      241 taatatcggt tcaaatagaa ctctaagtaa atggatagag caatatgaag aaggcggtgc
      301 ttcttcactt gagagccaaa aaaggggcag aaaaattagt atgaattcca agctaaacat
      361 tcctaaaaaa cttaaagatg agtctcttga agaagaagtt attcgtttaa gagcagagaa
      421 cg
//
LOCUS       DACDLM010000235          415 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.251, whole genome shotgun sequence.
ACCESSION   DACDLM010000235 DACDLM010000000
VERSION     DACDLM010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.251"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..339)
                     /locus_tag="IV356_003057"
     CDS             complement(<1..339)
                     /locus_tag="IV356_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP9016640.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYT"
BASE COUNT          116 a           70 c           68 g          161 t
ORIGIN      
        1 tgtataactc tgaacaggat ttttcttact tttgaaacgt ggaaatccaa cggatttatc
       61 ccgaaaaaaa ttcttgtatg ctttatctaa attaagttgg gcattggcta aagcaaggct
      121 atcaatttct ttcaaaaacg gaaattcttt cttgtattta gctggtgtcg gaaaagtcat
      181 ttttttagaa gaatcatttt taacttcttc atacgccttt tttcggtcat caagcattag
      241 attgtagacc ttacggacac aaccaaaaga tttggcaaag aagatttctt gttcctctgt
      301 tggatagatt ctgaatttgt atgcttttag ttgttccata aagttcacct actttctatt
      361 tatgattgtt tccttgattt tggatatact tcttaatcac atcaattggt gcgcc
//
LOCUS       DACDLM010000236          407 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.denovo.252, whole genome shotgun sequence.
ACCESSION   DACDLM010000236 DACDLM010000000
VERSION     DACDLM010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.denovo.252"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(100..399)
                     /locus_tag="IV356_003058"
     CDS             complement(100..399)
                     /locus_tag="IV356_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAP9016641.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT          123 a           77 c           54 g          153 t
ORIGIN      
        1 ttagaataaa aaaatacaga ctctgttcaa ataaatgaac ctagcctgca ttatgagatt
       61 gactatactt tttaattcat tgagatgaat aactcgtttt tataaatgcc caaaagtaat
      121 cggtgccgaa gccattcctc gacctaattc tttttcaaat tttcctattg ttgatatctc
      181 catataaaac ggtgatactg gtttagacaa ttctcccctg attgctaacg gacgtaaact
      241 acgttccaaa ttatttatga ctttaggata atactgacct ttttctaagc ctgtctttgc
      301 gtctatcaaa agtatacgtt ccttttcttt gatctctgga tttaaaacga gatcatataa
      361 ttttagtacc atgttttcta tttcttcact tttagacatc acgattt
//
LOCUS       DACDLM010000237        17958 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.guided.057, whole genome shotgun sequence.
ACCESSION   DACDLM010000237 DACDLM010000000
VERSION     DACDLM010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17958
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.guided.057"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(134..577)
                     /locus_tag="IV356_003059"
     CDS             complement(134..577)
                     /locus_tag="IV356_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HAP9016642.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(795..2135)
                     /locus_tag="IV356_003060"
     CDS             complement(795..2135)
                     /locus_tag="IV356_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP9016643.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2404..3300
                     /locus_tag="IV356_003061"
     CDS             2404..3300
                     /locus_tag="IV356_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HAP9016644.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(3450..4391)
                     /locus_tag="IV356_003062"
     CDS             complement(3450..4391)
                     /locus_tag="IV356_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAP9016645.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4517..5638
                     /locus_tag="IV356_003063"
     CDS             4517..5638
                     /locus_tag="IV356_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAP9016646.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYSLGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            5896..7398
                     /locus_tag="IV356_003064"
     CDS             5896..7398
                     /locus_tag="IV356_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HAP9016647.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            7465..7992
                     /locus_tag="IV356_003065"
     CDS             7465..7992
                     /locus_tag="IV356_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAP9016648.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            8203..9264
                     /locus_tag="IV356_003066"
     CDS             8203..9264
                     /locus_tag="IV356_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAP9016649.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            9267..10163
                     /gene="murQ"
                     /locus_tag="IV356_003067"
     CDS             9267..10163
                     /gene="murQ"
                     /locus_tag="IV356_003067"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAP9016650.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            10177..12159
                     /locus_tag="IV356_003068"
     CDS             10177..12159
                     /locus_tag="IV356_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP9016651.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="IV356_003069"
     CDS             complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="IV356_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HAP9016652.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            12881..14305
                     /locus_tag="IV356_003070"
     CDS             12881..14305
                     /locus_tag="IV356_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP9016653.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(14486..15259)
                     /locus_tag="IV356_003071"
     CDS             complement(14486..15259)
                     /locus_tag="IV356_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP9016654.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(15256..16161)
                     /locus_tag="IV356_003072"
     CDS             complement(15256..16161)
                     /locus_tag="IV356_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP9016655.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(16315..16635)
                     /locus_tag="IV356_003073"
     CDS             complement(16315..16635)
                     /locus_tag="IV356_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HAP9016656.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            17109..17795
                     /locus_tag="IV356_003074"
     CDS             17109..17795
                     /locus_tag="IV356_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HAP9016657.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            17797..>17958
                     /locus_tag="IV356_003075"
     CDS             17797..>17958
                     /locus_tag="IV356_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 family protein"
                     /protein_id="HAP9016658.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLG"
BASE COUNT         5778 a         3237 c         3701 g         5242 t
ORIGIN      
        1 ctgttcttat tacttgatgc agggcagctt tttcacaacc ccttattcac ggcgttccag
       61 aagtagcttc ttcttatttc ttgaagctga taacttctgg aacatcctct ttttttattt
      121 ggacggataa tggtcattcc atttctttga tcattttttt cattttgtcg atctcttctt
      181 cttgtgcctg aatgatttct tccgctaatt tttttacttc aggatctttt aaatcagctc
      241 gtttacttgc caggatagcg atagaatgat gaggaatcat ggccttcatc caagctgtgt
      301 cgttgacagt agtttggctt cgtaccataa acaaggaacc ggcaaaaaca agaagactag
      361 cggctaagat cataacattt atctttttgt tttcatacat tttccacatg aacaacagca
      421 tgatgactgc catgactgca cccatcatca acgccatgaa tactcgtgta cgactgaaga
      481 agatatgatc gagcgcatag acattcaagt acatcatacc aaacataact accgttgaaa
      541 caccgatcat caacaaaaac ttccaatact ttttcattta aaacaaactc ctttttttca
      601 ttcctttctt ctatcatgtc atgagcatgg agaacaatca attattttgc acagagggtt
      661 tttgaacacc gtttaccaag aggtcatgag actgtttatt cggaaaaagg agttgcaaca
      721 agacttttgt cacaactcct ttcttcaata gctccatcta ttccacataa ataaaataaa
      781 attttctatc gatttcattc attcgtcaat acgaacgcat cattcttttt ttgataactg
      841 aaataaatga acaggtaaag caggccagtc aatacagtta ccccaatgga gttcgtgaac
      901 aggataccaa ggaaaatcaa tcctaagaca gctaatgcaa aaaagctgat tcctttatcc
      961 cataatgttc cttttcttag tgccagtaca aaggatgccg cactgataat gatccagatc
     1021 aataatactg tatacgaaag ggaacctgcc agatagccaa ataatttgtc accgacaaaa
     1081 taagaaagag ctacaccaag ataaagaaca ctggtacaaa ataaaacagc acgttgcggt
     1141 acttgatgct tgtttaaaac agctagtttt ctagaggaac cttttcgatc cttcaaacgg
     1201 aagaacaaaa ttcttgaaga tgcatacaca cccgaattga tagatgagaa caaagcaagg
     1261 acaatcacaa aattgacgat atccgctgca aatgggatat tcattttttc aaataccatc
     1321 acaaaaggac tgacattcgt gcctgctaaa gtattccaag gaaaaagaat caaaagcaaa
     1381 aacaaaggaa tgatgtaaaa ggaaatgatt cttcccatga cacctttgat tgctttagga
     1441 atcgcacgtt taggatcatc tgcttcgctt accgtgatag caatcagttc agaaccgccg
     1501 taagaataga taactacaag caaagaactg atgattccct tcataccatg aggagtaaac
     1561 ccaccatggt cagtcaattg ctgaagggta gggaaaacgc ctgtgcccaa catttgctga
     1621 ccgacaagat aagtagcaaa aatgatcagt aagataatga cactgatttt agcaaaagcc
     1681 agccaatatt ctgtttctgc gaataaccgt accgaataaa gattgatgat cgtagttaaa
     1741 acagccaaca taaaaacaaa tacccaggct ggaatgtgcg ggaaccacaa ctgcaaaaag
     1801 gaagcagctg caacagcttc agcgatgata ttgataatcc acatagacca gtagacccaa
     1861 tcagtaaaat cagcagaatg agcacctaga taagggcgta tcaaaccaga taatccgtga
     1921 tgcgtgtcgc caccgcttaa aacgattttt cccagacctt tcatcacgat atataaaatc
     1981 agcccaccaa tcaaaaaagc aatcaataca gaagggccgg cgatcccaat cgcttcgcca
     2041 cttcctttaa atagacctgc accgattgct ccacctaaag ctaacatggt gatatgtctg
     2101 gagctaagtt gttttttcaa ttttttatct tccataaatg acctctttct tttaaattca
     2161 caatcaaaat ttatattaag aataaatagc aatatttaac aatgactaat gataacaaat
     2221 tttcagacaa ttacaactat tcagaaaact tttaggcgaa ttttaataga agaatgattt
     2281 atttcatcat attttcatac aaatgttaaa ttttcataca aatataggaa acgttttact
     2341 ggctttttac tatttaaaca ggctatcata ggaaaaagtg acagagaaag tgaggcggaa
     2401 aagatgaaca aaaatgacgt actgctagtt gcaaaaaata aatcacttta ttttttgcct
     2461 tccatccgct ctttagatgt ttggtccgga aaagatttac tacagtcgga attcattaaa
     2521 tcagctagac aacagttggc aaattatcag ctgatcgttt ttttagatta tggatttgat
     2581 atggagatgg ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt atttttttgg
     2641 aatcacttca aagcagaaca cgaggcgatg ctgaagcagg cacaagatga accggcaatc
     2701 gatgagattt atcattttga ttttttggaa gcaaaagaac ttgggctgaa acataatagt
     2761 tcattttatt cgaaacatat gaatttttct tctagcgaac caaagacgga tctatttttt
     2821 ggtgcaacga ataatgggag aaaagaacga gcagaaagct ataagcagga atttataaaa
     2881 agagatgtta cgaccaacta tttcattctt ccacatcgag ggaatgaaca acctggatat
     2941 cttacttatg aagagtacct gaaaaaaaca ggggaatcgc gcgggattct ggaactgttg
     3001 cgggagggtc agcaaggagt gactttgcgg acatttgaat ccatgtattt tcaaaagaaa
     3061 ctagtgacgg ataatcaagc gattgctcat tatcattttt atcgtcctga aaatattttt
     3121 ttgcttcgag aacgtgattt agatgaatta ccggaatttc tgcatacacc atttaagcca
     3181 atcctatcag agctattgga attttatgat gcagaaaatt gggcaaaacg atttatcact
     3241 aacgattcca ctatttatga gcaatacgaa tatgacctct cctctgttga aaacaaataa
     3301 aaaacctaca ttttgaagag attatgtact gaaacaaaca agcacaattc ttatggcatc
     3361 atgagagttg tgttttcttt ttgatctttt attgggctta aaaaaagaga accagctgct
     3421 gattcagctg attctcatca gagagccttt tattctgcgc caaggattcc ttcttttgca
     3481 tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt ttgtcctttt
     3541 cgccaaatgg caccattgat gtagtcgatt tcagtcaaac gatggttttt gatcaggtct
     3601 tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga agcaatatgt
     3661 tggtacactt cttcttgatc tagtatgatt ccttcttttg ctgcgataga agcaaattca
     3721 gatacgattg ttcgaaccat gctctctgcc gctttttgcg cgcctagttc agcaatatta
     3781 caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt tcgccaaatg
     3841 gaataacgaa cgttatggct atagatcgga tttaaatttg cttcttgaaa gacttctaca
     3901 actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat ttctccatca
     3961 cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt gatcccaaat
     4021 aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa tccatttagt
     4081 aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacaaaa catatcatct
     4141 aattgattgg cttttgttaa tgctacgatc aagtccacgt gttcgttgct ttcgatgatt
     4201 tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa gtcagcaatc
     4261 aacccatttg tacgaatggc ttcaatgtga gcaggccaac gatcgatcaa gaggacctca
     4321 tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc cccagctatt
     4381 gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta tatagaaaaa
     4441 tggaagaaaa tagcattgtt ttgtttgaaa aaaatgaaaa aaagtgtctt acttaagaag
     4501 aaagtgaggg atacagatgg atattttggc ggcaattgat tcatttaaag gaagtgcttc
     4561 ttcatttgaa ctaaatcagg cagttctaaa tggctgggaa gatcgtaaag gaagaaaaat
     4621 caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt acgcgctcag
     4681 gggaacatgg cgtaccattg atgggatgga tctcttattc cgtcagcgaa aaatcagcta
     4741 tttattgaca acttggcaag gaaaaaacac cgcagtcatc gaatctgcac aagcattggg
     4801 gttagatcta cttgataaac caacggatca aactatccga cttgcttcca gttattcctt
     4861 aggagaactt attaaagatg cactgcttca agaagtagaa caaattattg tcactttagg
     4921 aggaagcggg tgtagcgatg gtggtctagg attactccaa tccttgggtg cttctttaga
     4981 agggtacaca gaaggaaatc ctttattatc tactaaaaaa cttcattttg atcgaagaaa
     5041 cgttcttgtt tctaaagtaa aattgattat cgctgcagat gttaccaatc catatacagg
     5101 tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaatagata cgacgctagc
     5161 tttcttagat aaacaagcag gaaagattgc tcagcaaata aaagatttct gggaggtgga
     5221 tttagatgat attccaggaa gtggagcagc aggcggtatt ggtggagccc tttttttgtt
     5281 gggagcgaag atggtttctg gtttcgattt agtcagccaa atcactggat tggaaaaaaa
     5341 gatcgaacaa gcagatgtca tcattacagg agaagggcgg atcgatcagc aaacgatcca
     5401 cggaaaagtt ccatacggtg tagcagtgct tgcaaaaaaa tatcgaaaac caataatcgc
     5461 tatttgcgga agtagagacc aagagctaga aggactttct gattttctcc caattgtctt
     5521 aagtattcat ttgggtccaa taggtttaga agaagcaatg gaacacaggc aaacattaga
     5581 aaaaacaaaa atcttaggac agacacttag cagatttttc accatcctcc cgaagtagtt
     5641 gacaaaatca ttttctttat gctatcgtaa tttcaaatat aggacaaagt gagggatccg
     5701 tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct tgtggagaca
     5761 aggaagcagt gtgcagattt tcgggattgg cttggttttt tcgatgtatg ggtctttttg
     5821 tgtgtatcca acccttgcat cctctttagc cagttctgaa aataggactg gtcttttttt
     5881 acgaggtgat ggaaaatgtc taaaatcgaa ataaaaaatc tgacattcgg ctacgacagc
     5941 caaggcacat tattatttga acaagcaaat ctaaattttg acacacaatg gaaactagga
     6001 cttatcggac gaaacggtcg aggaaagaca actttactga atattctaca aaacaaacta
     6061 ccttatcaag ggcaagtaat ccatcagcaa gaatttgcct atttcccgca acagacaaaa
     6121 gataaagaac gtttaaccta ttacgtgtta aatgatatta cggattttga gatatgggaa
     6181 atcgaaagag agctccaatt gatgcaaaca gatcctgaaa tcttatggag agaattcagc
     6241 acactatcgg ggggagagaa gacaaaagtc ctactggcac ttttatttgt ggatgacact
     6301 catttcccgt taatcgatga accaacgaat catttggata tctctggtag aaaacaagta
     6361 gcggcttatt tgaaaaagaa aaaacaaggc ttcatcgtgg tcagccatga ccggggattt
     6421 atcgatgaag tagtggacca tgttttagca atcgaaaaaa gtcaactgga actttatcaa
     6481 gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga aatggctcaa
     6541 aatgaaaaat tgaaaaaaga agtcagtagg ctaaagaaaa cagcagctga aaaagccgaa
     6601 tggtctcgtt cccgagaagg agataaaaca aagaaacaag tcggattcat cgatactgaa
     6661 tctagacgag tgaataaagg agcagtgggt gctgatgctg cacggacgat gaaacgatcc
     6721 aaagcaatcg tgaatcggat ggagacccag atcagcgaga aagaaaaact attaaaagat
     6781 atcgaatata tcgattcttt gacgatgaat agccaagcgt ctcaccataa gcgactttta
     6841 agcgtagaag atcttcaatt agggtatgaa aatctgttat tcgagccaat tcattttaca
     6901 atcgagcctc atcagcgggt ggcgatttca ggtcctaacg gtgcaggaaa gtcatccatt
     6961 atccattatc ttctgggggc attcaacggc aaggttatag gagaaaaata ccagccaaaa
     7021 catctgagca ttagttatgc aagccaaaat tatgaagaca atcgaggaac gttggcggaa
     7081 tttgcagaga aaaaccaagt agactaccaa gcatttttga acaacctccg aaagcttggg
     7141 atggaaagag atgtttttca taacaagatc gagcagatga gtatgggcca acggaaaaaa
     7201 gtggaattgg ctaaatcttt atcacagcca gctgaactat atacatggga tgaaccattg
     7261 aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgatcttgaa cgtgaaacct
     7321 gccatgttac tagtggaaca tgatcaaacc ttcctggata aagtatctac tgagattatt
     7381 tctcttgaga gaatctaacc cttgtaatct caagaacaac aaggtatggt taaggggaac
     7441 tttgccaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga aacaacttgg
     7501 aacgcacaag gattagtttg cggacgggca gatgtgccgc tgactgaaaa aggacagatg
     7561 caggcacaga aactagcaga aaaggtagta gatttgcctg ttccaatcac gaaaatcatc
     7621 cattcccctc ttcaacgagc aagagataca gcacaagcag ttgctgatcg tctcagcttg
     7681 ccgctgaccg ttgatgaacg attggtagaa atggattttg gggattatga tggactgcca
     7741 agcaaagatg agaactttca aaaagcacgt ttagcgttcg ctgtacgatt cccaaatggg
     7801 gagtcagtct tagatgtgta tgcacggatc gttcctttat tgaaagaatg catcgaagac
     7861 gaagaaaatg tctatctgtt agtttgccat aatgccttga taagagtgat caatgcttat
     7921 tttcatccga tgcctaatga ggggttcttt acattcatgg tagataatac agaattggtt
     7981 tcttatgagt aattatgttt ttgtgttatt taaataaaat atttcaaggc actgcttttg
     8041 cttagcagtg ccttttttag gttatgacaa ttcttttgat aatataaact caacctttag
     8101 aaatgaaatt taattatttt aataaaagta ttgaaatttt gtttctttag atatatactc
     8161 tagtcataga aatgaagacg gatacagaaa aagagggata atatgtttgg cttttcaata
     8221 tttatgaacg attctttgtc agaagagaag aaacagtata tccgccaaat ggcatccaat
     8281 ggctttgtcg gtattttcac ttccatgcat ataccagaag atgatgtttc ggcatatcaa
     8341 aagcgattga tcgaactagg aagcgaagcg aaaaagaata aactagaatt gatggtcgat
     8401 atttcaggag aggcattgga acgagcgggt ttttcattag aagatctaac gcctttgaaa
     8461 gcaattggtg taacaggttt aagaatggat tatcatattt ccaatcagca gattgccgac
     8521 tggtcacatc aattgaaaat cagtttgaat gctagcacga tcacgcctaa agatatcgat
     8581 gaattgaaag aagcagaagc tgatttctca cagattgaag cttggcataa ttattatcca
     8641 cgtcccgaaa cagggctgga caaagaatgg tatcagaaaa aaaatcaatg gctcaaaatt
     8701 caaggtctcc ttgtccaagg ttttgtacca ggagatacag agttgagagg cccactatat
     8761 caaggattgc caactttgga agaacatcga gggatccatc ctcttgcagg cgctctagat
     8821 ctattagcaa gtaacacgga tattgtttac atcggagatg caggtctgtc agaaaacgtt
     8881 caggagcaat ttgcttcttt ccaaaaagaa cagacagtct tgctccatac ggaacctgta
     8941 gatgaagaat tttacgaata tatattaggg aagcatacga atcggcaaga cgatgcaaga
     9001 gatgtcatac gaagcgtaga tgcacgtttt cgagagattc cgcctatccc agcaagaaat
     9061 acagctacgc gtatgaaagg gtctattact ttagataacg aaaagtattt gcgctatatg
     9121 ggtgagatcc aattaaccaa atatgatttg ccagcggatg aaaaagtgaa tgtagtagct
     9181 aaagttatca aagaagagct accattgatc aaccaaatca aagctggtat gaactatcaa
     9241 tttataagaa aagaaggaag ataaaaatga gcaaaatcaa tttagagaac ctaacaacgg
     9301 aacgcagaaa ccaagaaact tttggattag atgagatgag tatttctcaa gccgttcaac
     9361 taatgaacaa agaagatcag aaagtggccg ctgcggttga aaaagaactg acaagtatcg
     9421 aaccagtgat tgctaacacg attgagtcct ttaaaaaagg tggacgtctg atttatatgg
     9481 gagccggaac aagtggaaga ctaggtgtgt tagatgctgc tgaatgcgta ccgacattcg
     9541 gtgtagaacc ggaaatggtc ataggtctaa ttgctggtgg agaagaagca atgactgtag
     9601 ctgtcgaagg ggccgaagat tcttatgagc tagggcaaga agatctaatc aagctgaatt
     9661 tgacaaaaaa tgatatagtt attggtatcg cagctagcgg tcgtacacca tatgtgatcg
     9721 gtggattaga ttacgcaaaa tcgatcggtg ctgtcacagg aacgatttct tgcaataaac
     9781 aagccgaaat cagtaaacac gcggatttcc caatcgaagt cgatgcaggt ccagaatttt
     9841 tgacaggctc tactcgattg aagtcaggaa cagcacaaaa acttatcttg aatatgattt
     9901 ctactatcag tatgattggt ataggtaaag tattcaataa cttgatggtc gatgtcaaac
     9961 caacaaatga aaaactaatc gaacgctcaa aacgaatcat catgcaagcg acagaagctg
    10021 attacgaaac agctgaaaag tactttgaag aagcagatca aaatgttaag ctggctatcg
    10081 tcatgatttt gacaaatagt gataaagagg aagctcaagc aaaattagct gaagcaaacg
    10141 gatttgtaaa agggacctta tgagggggaa aagaccatgg caaaaaacga actgactttg
    10201 gaagaactgg caaaacaaat ttataaaggg gcaggcggca tgggcaatgt agaaagcatt
    10261 gtccactgca tgactcgtgt gcgtatgaag atcatcaatg atgatcttgt aaatgtctct
    10321 gaattaaaag cgattccagg agtgcttggt gtagtagaag atgaacagct tcaagtcatc
    10381 atcggacctg ggaaagtgaa caaagtagca cagcaaatgg ttgatttggc aggcgtgaaa
    10441 ttaggagaaa aactttcttc tgtaagtaca gctacagcaa attcatcagc atctggaaaa
    10501 gaccgtgtaa acgaacgggc acaagaaatg aaagcggcac aaaaatcgaa acaaaaacca
    10561 tctaaaatca aatcggtatt aaaagacatt tctaatatct ttgtgccaat gattcctgca
    10621 tttgtcggta ctgggatcgt ggcagggatt gccgcagttt tagcaaactt agtcacagcc
    10681 ggaacacttg atgcagcaac atggcaacaa tatatcgatg tgatgaacat cttgaaaaac
    10741 gggatgttta gctacctagt tatctataca ggtatcaatg ctgcacaagt ttttggtgca
    10801 acaccaactc ttggtggagt tatcggggcc gttgtgatgc tgacagggat gaatccggaa
    10861 gcaccactga aaaacttatt tactggtgaa gctcttgcag ctggacaagg tgggatccta
    10921 ggtgtcatct tcgctgtttg gctattgtca atcgttgaga aaaaactgca taaagtagta
    10981 cctgatgcgg tagatatcat cgttacacca actctttcat tgattgccat cggtctgatt
    11041 gaaattttct tcatcatgcc tttagcaggt ttcatttctg atggcatggt cggtgggatc
    11101 aactgggtac ttggcgttgg tggagcattt gccggcttcg ttctaggcac attattcttg
    11161 ccgatggtta tgttcggact gcatcaaatt ttgactccaa tccatgtgca aatgattgat
    11221 gaaactggtc gtacgctatt gcttccaatt cttgcgatgg ctggtgcagg acaagtgggt
    11281 gcagcattgg cattatggat tcgctgcaaa aaagataaag aattaacaga aatgatcaaa
    11341 ggagctttac cagtcgggat cctaggaatc ggcgaaccat tgatttacgg agtaacatta
    11401 cctctaggac gcccatttat tactgcttgt atcggtggag gtatcggcgg ggcagtgatc
    11461 ggaatgatcg gaaatgtcgg ggctatcgct attggacctt caggagccgc tttgatccca
    11521 ttgatctctg acggtaaatg gttaggctac atccttggat tattggcagc ttatgctggt
    11581 ggcttcgttg ctacattctt cttcggtatt cctaaagacc gtttagaaaa agaagaatta
    11641 gcgactgaaa cagccacagt aaatgaagtg cctgaaaaag tagtacctca aacttcagct
    11701 gaaagtgtga ctatcctctc atcagttgct gacggaacag ttgtttcttt agataaagca
    11761 agtgatccag tttttgcaca aaagatgatg ggtgaaggct actttgtaga accagaaaac
    11821 ggacatatct attctccagt tactggggta gtcagctctg tcttcccaac gaaacacgct
    11881 attgggatca caacgccaaa tggtttagaa atcttgcttc atatgggaat caacacagtt
    11941 gacttaggcg gtacgccatt tgatgtgaaa gtaacagaag ggcagcaagt gacacctgat
    12001 acgcttgtag cagaagctga cttagaagcg atcaaagcag caggcaaaga aacatccatg
    12061 atcgtcttgg taaccaatat ggatcgtgta aaaaactttg tcttggaaaa aacaggtaaa
    12121 gcaaaagcaa aagcacctgt gatggatgtc aaagcttaat atgatagaaa caatagaaac
    12181 gaaagaagaa actgaaatct atttttcagc ttcttctttt ttattattta ttgttttctg
    12241 ctaaaatctg ataaattcgt gtcacatcag atggtgttcc ccgtaattca taatctgcca
    12301 agaaaggaaa gccaaatgtt tgtgcatatt gtttggctgt tagacaatac tgattattga
    12361 agtttttatt tccgctaccg actacaccaa gacaaagttt atgattgtct tcatgttcca
    12421 gatattcacg catcgtttcg gtcaagattt ctgtatcacc gttatctaaa ccatttccgc
    12481 cgtctaaata agtaggaacg aaagtaaaaa atggttctgt ttctttcgta aaatcactat
    12541 tttcatggat ttcttttaaa gtaacttcag gattgacagg atcttctgca tgcatttttt
    12601 cagcatattc tgctagatgt ttggcaaagg cacgcgtatt tcctgaaatc gatatatata
    12661 aaatgttcat ggatcatcct ccaattcttt ccttttagta tagcatcttt tttaagtttt
    12721 ttggtggtgt aatttggaaa gggactaggc gctttgcttg tataatgaga aaaaagccgg
    12781 tagaattata tttctattaa agtttttatt aattaagtaa aaataaaaaa ggtttgttat
    12841 actttttgat aaaagcggtt ttattttgga ggatgcttac atggatacag agcaacagaa
    12901 aaaaggaatt ggtttaattc cacttgctgc cttagtaatt ggttcagcga ttggaggtgg
    12961 cgtatttggt attatgacgg acatctccgg atcggctggc ggcccagcta ttttcagttg
    13021 ggtactcgta ggaacagcaa tgttgatgct ctccttgtcg atcaataata tcaataaaaa
    13081 acgtccagat ttaaaaggcg ggatctttag ttacgcagaa gaaggttttg gccgtttcgc
    13141 tggttttatc agcggttggg gttactggct cacatgctgg ttaggcaacg tagcttttgc
    13201 aacattgttg atgagcgcat taggatattt cttcccagta tttgaaggtg ggcaaaatct
    13261 ggcatcgatc gtgatgagta cagtcttttt atggggatat gcatggctag tgaatcgggg
    13321 agtcgaaaat gctagtttcg tcaatgctat cgtcacattc tgtaaattag tgccattatt
    13381 tttatttatt gtagtagcta tcagcacgtt ttcgatccaa caattcattg ataacttttc
    13441 tagcgacatt atattgaatg cgaatggaca gccgatcccg ttttccagtc aagtattgag
    13501 ttgcatcatg gtgatgcttt gggtatttgt tggtattgaa ggagcctctg tcgtaggttc
    13561 acgagcaaaa aaacaatcag atgttgggaa agcaacgatt ctagggatat tcggcttgat
    13621 tattatttac gtcttggttt ccatgcttcc atatgggaca atgacgatga atcagctgca
    13681 aacgatcaag gcgcagcctg ctatgggcta tgtgtttgaa atgatggttg gtaaatgggg
    13741 agcagtcgtg atcaacggcg gtttgatcat ttctttagtt ggtgtttggc tctcatggac
    13801 gatcttaccg attgaaacaa tgggaaacat ggctgaagac ggacttttgc ctaaagcatg
    13861 gggaaaactc aacaaaaatg gggcaccaac ttatgctatc gtattgacga cgttatgtac
    13921 gaatgtcttt ttactttcat tattattcac tgacagtgct tataactttg cttacacact
    13981 tggtacagca gctattttct tcacgtggct tttcttagga ttgtaccaaa tgaaactttc
    14041 ttatcagcgg aaagaatggg tccaattttt agtagggctt ttagcaagtg cctttcaagt
    14101 atgggctatg ctagtcgtag cctttaatga agtaatgctt gttcttgttc ttttcttgcc
    14161 aggcatttat ttttacctca aagcacgtaa ggagcaaaac gagcctgtac aacatatcca
    14221 cttagataag attttactta taggtgtgac gatggtcgga gtgattgcaa tggttttatt
    14281 tgccactggg atgcttcacg tatagaagta taaaagaagt ataaagagag gttgtgagcc
    14341 tgtcgtttat tcaaaaacat actaggaaag gagctgtgac acaaatgttg tcacagctcc
    14401 tttttcagaa taaacggtgt ttaagagaca gccaatcggc aataaggctg aacgtctctt
    14461 tcacagcctc ttttttgatg agtcatcata cattttttcg cttaaatacg agatatccta
    14521 atgctaagaa caaaacgatg taagctaaat taccgaatag catttgatta gtagaaagat
    14581 gagtcaattg cttcatgatc tcttcgtttc caatttggtt ttgcagattc aacatactga
    14641 tcggattcca tttgatccac tcccattttt ggatgagtgc aataaggata ccagatatga
    14701 ttgacgaagc aaaataaaag acgattcctg ctgagatgga tgcaccggaa ctattgataa
    14761 agcaagcaat catcaacact aaacttaaaa tcagccataa accgatataa ctacccaaag
    14821 tataagtgaa caagctttgg atcagtgttt gaccagtaga aaccttctcc gtgaaggaaa
    14881 tcgaagggaa aagaatcagt ttcatcaaca cagtgacaat aatagctaaa aggtataaat
    14941 aaacagaata aataactaat gtgatccatt tgcttactaa tatttctcct cgagaatact
    15001 ttcgataaag gagatttttc aatgtaccat attgtgcttc catcgaaatg atcgtgcttg
    15061 cagctgcaat catgataaag acaatccaag atgtggcact aaaaagctga gcagtcattt
    15121 caactggatc aatgatcgtc gtgtattttt tggctagaag tgctgttcct atgagcaaaa
    15181 caactaatag aacagataaa acagcagttg actttttctt gatcaattta aataattctt
    15241 gttttacaag caatgtcatt tttcttcttc cccctttact gaatccagaa tttccaatag
    15301 agaagattcc aaatcattcg tcagatgctg gacgtctgtc acatggatat tttgtgcaga
    15361 caatagctgg atcacggttc ctaataattc ttcgttttct tttaaaagct tgattttatc
    15421 aggatcttcc aaagtatatc cagcttctgt caagatcgtt cgagcagcta gatcatttgt
    15481 tgtagagata acgatgaaat cttgcgctgt ttggttcaat tcagccattg tacattgttt
    15541 gatgatcttt ccttgattga tcaggatcag ctcatcgacc attttttcaa gctcgctgag
    15601 taagtgactg gagatcaaga aagaggtgcc ctgagtagcc aagtcggtaa tgatttttcg
    15661 cacatctctt gttgcttgtg gatccaaacc gttcatcggc tcatctaaaa taacgataga
    15721 cggatggttc agtaaggcaa gagcaattcc caatttttgt ttcattccca acgagtagga
    15781 tttcgctttt ttgtgaatgt acttttccat cttgagctga ttcacgatag tgtcgatagc
    15841 agatacatcg ttggtttcag agaataactt cagatgatca tagcctgtta agaatggata
    15901 gatacccggg tattcgatca atgctcctac ttgttccaac cctttatgac tagagggaga
    15961 aatctcattt tcaccaatac agattgttcc atctgagtaa tggatcagtc ctaaaatagc
    16021 tttcatgatc gttgtttttc cagcgccatt aggacctact aatccaacga ttttgccagg
    16081 ggataagcta aaactgacat cgctgagggc ttgtttgtga ccaaagttct tggataattc
    16141 ttggaccgaa agacttttca aaaatattca ctccttttct atagatagta caagcataca
    16201 cctgatgagt ggagaagtcg ctaggtcatt ggacttattt cttatttttt cataaaaaaa
    16261 ttgaatatta aataaaaagg cttatttttt ctgatcagta cttattccaa gtgtctagtg
    16321 gccgctagta atcttgatgc caatgatact gatgagtagc atccccacaa agaaccaagt
    16381 ggaaagattc agcttatcat gaaacaagac cacaccaatt atgaccgaac caactgcgcc
    16441 aatccctgtc cagataggat aagagagact catcggcaaa cttttgattg cctttgacaa
    16501 aaagtaaaaa ctagcaatca tgccaatcac tgtgtaaaaa gaataattga ttttagaaaa
    16561 accatcactc catttcatca tcgttgacca gaatacttcc aaaattcctg ctatgattaa
    16621 ttccatccat gccatactta cattcctcct taactataaa aaaatacaca aaaagaggaa
    16681 aatcatccct tcaaagacct aatggaatga tcatcctctt tatcctaccc ggtggcagat
    16741 tgtatatctt tttctgtagt atagcacacc tatccagata tcggcaatct catacttttt
    16801 agtaaagtgt accaagcact gacggatata tcgttagcgg aaaagaagat gaatgctttg
    16861 caatttcata gaaagaagtt gttatttatt aatcatttaa aaaaaacagt aactagacct
    16921 tatttctata tattatcggg caataaatta aaaaaagctt taccttacaa taagtaagat
    16981 aatttttgtg ataaaaaaat aacgaaaaat atttaaaaat agtgtctatt tcgtgagaaa
    17041 acaactatat tttttatgtg ttttgcttta taattaaaaa aatattgtca ttttatggag
    17101 gaaaatatat ggaaaattat cttagccttt taggcgtctt gattgttatt ctcgggtttg
    17161 catttaaatt agactcgata ttgatcgtaa tggttgcttt agttgttaca gctttgactg
    17221 gcggtcttgg cattcaagga atgttagaac ttttaggtac aagttttgta aacaatcgcg
    17281 ggatggcgat ttttatcatc attatgttgg caacaggaac gcttgaaaga aatggtctga
    17341 aagaatcagc ggcttccttg atcaagcgat tcaagaaagt atctgctggt atgattgtag
    17401 atatttatgg gatctttcga atgatctttg cggcttttaa cgtgagtttt ggtggagttg
    17461 ctggatttgt tcgtccaatc attttaccga tggcattggg gaccatcgaa tcaaaagggt
    17521 tagaagtcca tcctaagcat gaagaagaac taaaaggtat ggcttcagct atggaaaatg
    17581 tctgctggtt ctttggccaa gtactattca tcggaggagc aggggcgttg ctagtccaat
    17641 caacactgaa agatctagga tatgacgtaa cattgggaca gcttgcttta gtggaagttc
    17701 cagtggctat cacggcttta gttgtggcaa gtgtctactt ctatcttaaa gaaaagaaat
    17761 tagcgaagaa atattatcca ggaaaggggc aataagatgg acttttttac aaatcctgat
    17821 attttattag gcgataaatt actggagatc ctttatatcg tgatgggact cgtattgatt
    17881 tacactggag taagaaattt aacagataaa accaatcctc atcgttatgg gtcagccttt
    17941 ttctggacgg tcttaggg
//
LOCUS       DACDLM010000238        15087 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.guided.064, whole genome shotgun sequence.
ACCESSION   DACDLM010000238 DACDLM010000000
VERSION     DACDLM010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15087
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.guided.064"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..1414
                     /locus_tag="IV356_003076"
     CDS             <1..1414
                     /locus_tag="IV356_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP9016659.1"
                     /translation="ADAVSSRFSDAAEANTVKAACAKAQAVCVSVTREKKTEQPPKLY
                     DLTTLQREANRLFGYTAKQTLDYAQALYLKKLLTYPRTDSQYLTDDMLPAVESLVSGL
                     WELVPFAKGLNLSPQFDRILNSKKVSDHHAIIPTAEFVKQGFGTLAESEKKLLSLICC
                     KLLCAVAGPHIYEAVTATFTCAGQEFTAKGKTVLSPGWKEIERRFRSSLKTDADEDAE
                     AVRELPELCEGQTFADVAASVTEHFTTPPKPYTEDTLLSAMERAGAEDMPEDAERKGL
                     GTPATRAAILEKLVQMGFVQRKGKQLIPTKDGINLAVVLPEALTSPQLTAEWENRLTE
                     IAKGQADPDEFMDGIETQARELVQTYSCISEEKQKLFQAERVPIGTCPRCGEAVYEGK
                     KNYYCGNRACQFVMWKNDRFFEERKKAFTPKIAAALLKTGKVKVKGLYSVKTGKTYDG
                     TVLLADTGGKYVNYRIEHRS"
     gene            1563..5483
                     /locus_tag="IV356_003077"
     CDS             1563..5483
                     /locus_tag="IV356_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HAP9016660.1"
                     /translation="MNEVFSIQVHNRQFLEQGKQGVWLDLPTTTETLQAALRDVGITA
                     DNPQDFFINGYSCPEDRHLAIPYDMVLAADVDELNFLAARLGQLDAAEIAELNAALQN
                     PRGGFENIGQIIDYTENVDYYVHLPDVRGDGQLGDYYLNRSGMVDMPEEWKAGIDTAQ
                     FGRHIAQQEQGVFTQYGYLVRSGDEWQRVHEGQPVPEEYRVMHYPQPEADREEPQAQQ
                     PEASESPDKAPPPVIPIMLDGMNSKERMKVITDRLETGVQELFESSRYMAYLSAMSKM
                     HDYSLNNTLLIAMQGGSIVAGYNRWQDEFDRHVKRGEKGIKILAPAPFKVKQQMEKID
                     PATQQPVIGADGKPVTEEQEVTVPAFKVVTVFDISQTEGKDFPMPYISELTGDVQQYQ
                     DFFAALERTSPYPISIEPISDGAKGRCFYAKQRIAINEGMSELQTLKTAIHEIAHAKL
                     HAIDREAPAEEQAARPDRSTREVQAESVAYTVCQYYGLDTSDYSFGYVADWSSGRELS
                     ELKASLETIRATASELITEIDGHFAQLQQEREARQEQEAVTVDVTPEAAAPAQAEEEQ
                     APALDPAAEPLVTVLWSESPQLKDGQQMPLHEADALFARLDAAYPAEAGYDKTAFRID
                     CIFQGEPDSYEGRQDFGDRDGSLIEHIQSYHQFYAQDENWKKHVIATTGIEGWEQDKA
                     HRDMLLGEFVPYMKLHCSLAQMEQTAQGRLQSGETLTPEETAYLGALLSYVQECRPML
                     NQGQYQLPEPPKLADFDQSLQDYKAQVQAEIAQEAAAAGMTVEEYAAAGYEAPQQDTF
                     SIYQLRGGEETRDYRFEPYERLQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNID
                     HPADFRGHSLSVSDVVVLHQNGQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNEN
                     MIDGIINNTPPEPQPEEPEQLSFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAAR
                     RAKEAMSFSDYRPGSATAEYRHYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLA
                     ENMNKGYEITARVPSVLIAGPSNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGM
                     GGISADDPQAVSKLEKKLEKLEASQELMKAVNAYYRKHGTLDGCPHLTERGIENLKAD
                     MASGWHYEKKPFQSWQLSNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVA
                     NRLQIFFEGKPDAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEK
                     PSALQLAARREKEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            5484..6428
                     /locus_tag="IV356_003078"
     CDS             5484..6428
                     /locus_tag="IV356_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016661.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            6432..6635
                     /locus_tag="IV356_003079"
     CDS             6432..6635
                     /locus_tag="IV356_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016662.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMPVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(6935..7171)
                     /locus_tag="IV356_003080"
     CDS             complement(6935..7171)
                     /locus_tag="IV356_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP9016663.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(7354..7725)
                     /locus_tag="IV356_003081"
     CDS             complement(7354..7725)
                     /locus_tag="IV356_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016664.1"
                     /translation="MSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECICVQSI
                     SYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAACSKRM
                     RRRKEAERQRKRYWKPTHLEL"
     gene            complement(7722..9050)
                     /locus_tag="IV356_003082"
     CDS             complement(7722..9050)
                     /locus_tag="IV356_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAP9016665.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            complement(9011..9340)
                     /locus_tag="IV356_003083"
     CDS             complement(9011..9340)
                     /locus_tag="IV356_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HAP9016666.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            complement(9598..9969)
                     /locus_tag="IV356_003084"
     CDS             complement(9598..9969)
                     /locus_tag="IV356_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP9016667.1"
                     /translation="MANIEDCPGFETFGADVKAARQAKRVSRKAMAEKINIDWRYLAN
                     IENDGAIPSLPVVIQLIKACGLPVERYFNPEIMREESELRQRVSHKLKLCPEEYLPII
                     EGAIDSAILIEKPKKNETEDV"
     gene            10114..10299
                     /locus_tag="IV356_003085"
     CDS             10114..10299
                     /locus_tag="IV356_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAP9016668.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            11242..11901
                     /gene="vanR"
                     /locus_tag="IV356_003086"
     CDS             11242..11901
                     /gene="vanR"
                     /locus_tag="IV356_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HAP9016669.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDLEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFESDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            11904..13247
                     /gene="vanS"
                     /locus_tag="IV356_003087"
     CDS             11904..13247
                     /gene="vanS"
                     /locus_tag="IV356_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HAP9016670.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPDFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQARSRKSGRNGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLTSTL"
     gene            13418..14224
                     /gene="vanY"
                     /locus_tag="IV356_003088"
     CDS             13418..14224
                     /gene="vanY"
                     /locus_tag="IV356_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-B/VanY-G family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HAP9016671.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGRR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            14237..15073
                     /gene="vanW"
                     /locus_tag="IV356_003089"
                     /pseudo
     CDS             14237..15073
                     /gene="vanW"
                     /locus_tag="IV356_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance accessory protein
                     VanW-B"
BASE COUNT         3803 a         3838 c         4059 g         3387 t
ORIGIN      
        1 cgcggacgcg gtaagcagcc gcttttccga cgctgccgag gcaaacaccg tcaaggcggc
       61 ttgtgcaaaa gcgcaggccg tttgcgtttc cgtgacgcgg gagaaaaaga cggaacagcc
      121 gcccaagctc tatgacctta ccaccttgca gcgggaggct aaccggcttt tcggctatac
      181 cgccaagcag acccttgact atgcccaggc actgtatcta aagaagctgc tgacctatcc
      241 gagaacggat agtcaatatc ttaccgacga tatgctgccc gccgtggaaa gccttgtgtc
      301 cggcctgtgg gagctggtgc cgtttgccaa gggcctgaac ctttccccgc agtttgaccg
      361 catcctgaac agcaaaaagg tgtccgacca ccacgccatt atccccaccg ctgaatttgt
      421 gaagcagggc tttggcactc tggccgagag tgaaaaaaag ctgctgtccc tgatctgctg
      481 caagctctta tgtgccgtgg ccgggccgca tatctatgag gccgtcaccg ccacatttac
      541 ctgtgccggg caggagttta ccgccaaggg caagaccgtc ctttcccccg gctggaaaga
      601 gattgaacgc cggttccgtt cttccttaaa gaccgacgcc gacgaggacg ccgaggcggt
      661 gcgggagctg ccggagcttt gcgagggcca gacctttgca gacgtggccg cctctgtcac
      721 cgagcatttc accacgccgc ccaagcccta caccgaagat acgcttttgt ccgctatgga
      781 acgggccggg gccgaggata tgccggagga tgccgagcgc aagggattag gcacaccggc
      841 cacccgcgcc gccattctgg aaaagctggt gcagatgggc tttgtccaga gaaaaggcaa
      901 gcagctcatt cccaccaagg acggcatcaa tctggctgtg gtgctgccgg aggcgcttac
      961 ttctccccag cttactgccg aatgggaaaa ccggctgacc gagatcgcca aggggcaggc
     1021 cgatcctgac gaatttatgg acggcatcga gacgcaggcg cgggagctgg tgcagaccta
     1081 ttcctgtatc agtgaggaaa agcagaaatt gtttcaggcc gagcgtgttc ctatcgggac
     1141 gtgtccccgc tgtggtgagg ctgtctatga gggcaagaaa aactactact gcggaaaccg
     1201 ggcctgccag ttcgtcatgt ggaagaatga ccgatttttt gaggaacgca agaaagcgtt
     1261 caccccgaag atcgccgctg cgctgctcaa aaccggcaaa gtcaaggtaa agggcctcta
     1321 ttccgtaaag accggcaaaa cctacgacgg gacggtgctt ttggctgata ccgggggcaa
     1381 gtacgtcaac taccgcattg aacacaggag ctaaaggaca gtaacacagc aagcataggg
     1441 agtgtggcta cactcccggt aaaatccccc ggccgcgtcc ctgccgggcc ggggattttt
     1501 gcttgttggg gaagtcccca accccctatt ttttgaaaca gaacagagaa aggagtgacc
     1561 gcgtgaacga agtattttct atccaagtcc ataaccggca gtttttggaa cagggcaaac
     1621 aaggcgtctg gctggatttg cccaccacaa ccgaaacgct gcaagccgcc ctgcgggatg
     1681 ttggcattac tgccgacaat ccgcaggatt tttttatcaa cgggtattcc tgcccggagg
     1741 acagacacct tgccattccc tatgacatgg tgctggccgc cgacgtggac gagctgaatt
     1801 tccttgccgc ccggctgggc cagcttgacg ccgccgagat cgcagagctg aacgccgccc
     1861 tgcaaaatcc ccgtggcggc tttgagaata tcggccagat catcgactac accgaaaatg
     1921 tggattacta tgtgcatctt cccgacgtta ggggggatgg acagttgggc gactactacc
     1981 tgaaccgttc cggcatggtg gatatgccgg aggaatggaa agccgggatt gatacggcgc
     2041 agtttggacg ccacattgcc cagcaggaac aaggcgtttt tacccagtac ggctatctgg
     2101 tgagaagcgg cgacgaatgg cagcgcgtcc atgagggcca gccggtgccg gaggaatacc
     2161 gggtgatgca ctacccccag ccggaagctg accgggagga accgcaggcc cagcagccgg
     2221 aggcatccga aagccccgac aaagcgccgc ccccggttat cccgatcatg ctggacggca
     2281 tgaacagcaa agaacgcatg aaagtgatta ctgaccgtct ggaaaccggc gtacaggagc
     2341 tttttgaaag tagccgctat atggcttact tatccgctat gtccaagatg cacgattaca
     2401 gtctgaacaa tacgctgctg atcgccatgc agggcggttc gattgtggcg ggctataaca
     2461 ggtggcagga tgaatttgac cgccatgtga agcggggcga gaaaggcatt aagatactgg
     2521 ccccggcccc gttcaaggtt aagcagcaga tggagaaaat cgacccggcc acccagcagc
     2581 ccgtgatcgg cgcggacggc aagcccgtga ccgaagaaca ggaagtgacg gttccggcct
     2641 ttaaggtggt gacagtcttt gacatcagcc agaccgaggg caaggatttt cccatgccct
     2701 atatcagtga acttaccggc gacgtgcagc agtatcagga tttctttgcc gcgctggaac
     2761 ggacatcacc ctatcccata agcattgagc cgatttcaga cggggccaag ggccgctgct
     2821 tctacgcaaa acagcgcatt gccatcaacg agggcatgag cgaattgcag accctaaaga
     2881 ccgccatcca tgagattgcc catgccaagc tccacgccat tgaccgggag gcccccgccg
     2941 aggaacaggc ggcccggcca gaccgcagca cccgcgaggt acaggccgaa agcgtggcct
     3001 ataccgtctg ccagtattac gggctggaca cgtcggacta ttcttttggc tatgtggccg
     3061 attggagcag cggcagggag ttatccgagc tgaaagcctc ccttgaaacc atccgggcca
     3121 cggccagcga attgataacc gagatcgacg gccattttgc ccagcttcag caggagcgcg
     3181 aggcccggca ggaacaggag gccgtcacgg ttgacgttac cccggaggca gcggccccgg
     3241 cgcaggccga ggaagaacag gccccggccc ttgatccggc agccgagccg cttgtgactg
     3301 tgctatggag cgaaagcccc cagctaaagg acggccagca aatgccgttg catgaggccg
     3361 acgcgctgtt tgcccgtctg gatgcagcat atccggcaga ggcaggctat gacaaaaccg
     3421 cgttccgcat tgactgtatc tttcagggcg agccggacag ctacgagggg cggcaggatt
     3481 ttggagatag ggacggttcc ctgatcgaac atatccagag ctaccaccaa ttttacgcgc
     3541 aggacgaaaa ctggaaaaag catgtaatcg ctacaaccgg catagagggc tgggagcagg
     3601 acaaggccca tcgggatatg ctgttaggcg agtttgtccc ctatatgaag ctgcattgca
     3661 gccttgccca aatggaacag acggcgcagg gccgcttaca gtccggggaa accctgacgc
     3721 cggaggaaac ggcctatttg ggggcgcttc tctcttatgt gcaggagtgc cgccccatgc
     3781 tcaatcaggg ccagtatcag ttgccggagc cgccgaaact ggctgacttc gaccagagct
     3841 tgcaggacta caaagcacag gtacaggccg agatcgcgca ggaggccgcc gcagccggta
     3901 tgaccgtgga ggaatacgcg gcggctggct atgaagcacc ccaacaggac accttttcca
     3961 tctaccagct tcgaggcggg gaggaaaccc gcgactatcg gtttgagcca tacgagcgtt
     4021 tacaggccgc agggctggcc gtggacagtg ccaactatga ccttgtttat acggcaccgc
     4081 tggataaaag cacgtctttg gaggatattt accgcacatt caacatcgac cacccggcag
     4141 attttagggg acacagcctt tccgtttccg acgtggtggt gctgcaccag aatggacagg
     4201 acaccgccca ctatgtagac agcttcggct atatggaagt gccggagttt ttgcgggaaa
     4261 atcccctgcg taccgccgaa ctgtctacgg agcagaacga aaacatgatt gacggcatta
     4321 tcaacaatac gccgcccgaa ccgcagccgg aggaacccga acagctatct tttgaggatg
     4381 tggcagttgc ttccggccag acacaggagg aacccccgga ggctgcgccc ccgcaaacgg
     4441 ctgtccgcta ttatcccatc aatgagggag ccgcccgccg cgccaaggaa gccatgagct
     4501 tttctgacta ccggcccggc agcgccacgg cggaataccg gcactatgtc gatcaggccg
     4561 tggaaattgc ggagcgccag aaaaagcgtg tggagccaga gtatcacgaa aagatagaca
     4621 gcctccttga cacctacgcc cgcaagctgg ccgagaacat gaataagggc tatgagatta
     4681 ccgcccgcgt cccctctgtc ctgattgccg ggccgtccaa tttcccggta cgggcgaaag
     4741 aaaagcagaa cgccgccagt gaccgcaaca tggaggaatt tcagtacatt cagggcttgc
     4801 ttgacaaaat ccgcagcacc ggcatgggtg gtatcagcgc cgacgatccg caggccgttt
     4861 ccaagctgga aaagaaactg gaaaagctgg aagcgtcgca ggagttgatg aaggccgtca
     4921 atgcctacta ccgcaagcat gggacgctgg acggatgccc ccatctgacc gaaagaggca
     4981 ttgaaaacct gaaagcggat atggcgtcgg gctggcacta tgagaaaaaa ccgttccagt
     5041 cctggcagct ctccaacaat aacgccgaga tacgccggtt aaagggccgc attgaggaat
     5101 tgacccgcca aaaggaggcg gcctatgtgg gatgggagtt tgacggcggc actgtggaga
     5161 tcaaccgggt ggccaaccgc ctgcaaatct tctttgaggg gaagccggat gctgctgtac
     5221 gcgacgagct gaaaagcaac ggtttccgct ggtcgcccaa ggccggggca tggcagcggc
     5281 agttaaacga caccacaatc cgcgtcgctg accgtatcaa gtgcatccag cccctttccg
     5341 gcgaaaagcc cagcgcctta cagcttgcgg cccgcaggga gaaagaaaag ccctctatcc
     5401 gggcgcagct caacgcggcc aagaccgaac aggccaagca gccaccggcg cgggaaaaat
     5461 caaagggatt ggaggtagag taaatgcaga agtttgaaaa tgtggacgtt ctggccgcgc
     5521 tggaacagat catgcggcag aacaccgcgt tttatcaaag tgactttggc attgacaaag
     5581 acattatcag gcgggatgcc gccagcgatc aggccgcaga caagaccctg ctctggatgt
     5641 cccggccctc cgggacgtac tgtttccggg aacgtgatgt tttcctgaaa gacacccgac
     5701 agtacaacac atggaaattt tacggggagc agacccgtga caagatactg gcctacgcgg
     5761 tggagctgac cggcacacag ggcggcacta tccggggcaa tctctatgag ctggactatc
     5821 cgcagcattt ccggcacgtc attgaaaccg cccagccggt gagtgtgaac cggctctttt
     5881 atgagcatgg cacccgtgac atcccggaga gccagcgttt tgacggaagc cctgaccggg
     5941 tattgggaaa ctttttgtac tatgaggccc agccccatga cccggctgtg ctgcaggagg
     6001 cgctacggac ggagcagcac agccgggggc gggccgtccc cggcgatttc aaagtccacg
     6061 tcaccgcttt gcatgacagc cggattgaaa ccgaggcccg gcgtattgtg gacagcctga
     6121 aagatctgtc cgcgcctaac agccccaata aaacgcattt catggtggag atctccccgc
     6181 actttgcggc gattgcttcc accaaggata atgaccggct ctttgccatg ctgccctata
     6241 aatccctgtg ttttaccggg atgaaaggca ggcatggcgt gtatgccgtg attaaccggg
     6301 acgagcgccg ggatgtgagt attcgcaggc cccggccctc tatccgcaag cagctatccg
     6361 acagcaaaca ggccgccagc ccaaaaaagg cggcggccag aaccaaaaag aatgaattgg
     6421 aggtataagg aatgatgcac tttaccgtgg aggaagaaaa cctgatctgt atgtaccaca
     6481 atgcagaccg gcgcagaacg ataaacaggc tcaccgccgt catgccggtt atggatgggg
     6541 atatgcgggc gcaggcccag cagacccttt ccaagctgga acgcatgacg gatgccgact
     6601 atgacggcca gaagttccac ttcacagacg aataacgaac agcagacgcc gggcgcggcg
     6661 gccatgtggt cgcttgcgtc cggcgtcttt tctttttgcc tattcctacg catttagaac
     6721 ccggtattgt cggggatagg atgaagtatt cgcttgcccc tgcaaacatg cgggagaagc
     6781 cttgcagcgg gcggttttca atcccttaaa tgcgtaggtt gcagctataa ttagacccct
     6841 gaaacagata tagccgcgca gcgggtgtat ctgtttcagg ggtgtgcagg tgatagccgc
     6901 aaagcggcgt aagagggtgc agccctcttg ccgtctatct ctgttccagc gggaagctcg
     6961 gcaatgcttc cagcagtttc agggaaatgc gctgccgtat atcttcgtca atgactttct
     7021 tctttttgcc gtttgcctgt ctgatctcca ccgtggaaag ctcgttgatg tagtcagcat
     7081 aatgggccaa cactttttcc gtggcccacc tctcaccggc aacggcggct ttgatcgttt
     7141 catagtccag cagcttttct tgtccgtcca tcctgatacc cccgtcagac tgattttttc
     7201 tatgatacca tattcggaag catggaacca gagaaaacgg cgcttttctg ctggtaaatt
     7261 ctacgcattt agaacagcac ttcggcgggg ataggataaa acacccacat accccgctga
     7321 ccatgccgga aaagccttga aatataaggg cttttacagc tctaagtgcg taggtttcca
     7381 gtatcttttc cgctggcgct cggcctcttt gcggcggcgc atccgtttgg agcaggccgc
     7441 gcagtatttg gcccggttag acttcggcgt gaacgtggcc ccgcactcac agcagcgttt
     7501 cacttcgtcc cggtctttgg tgatctcggc atacagggcc gcatccagcg ggaggacagc
     7561 ggccttaaac cagcggcaca gaagcgaata ggaaatgctc tgtacgcaaa tacattcttc
     7621 gccgtcgtcc agcaacaggc agttgccgtc acaatagttg cagcactcat gcgtcagctt
     7681 ccgggccttg cgatattgag ggtaattcat tcgtggaata ctcatagctc ttgcgtccat
     7741 tcctttcccg gcgtcatacg caaaatgccg tccacattct gcttgatgat gccgtattcc
     7801 tgcatctgct ttttcgcttc gccgtacttc tcatacagcc gttccttttc ctcggccaat
     7861 cgcttgtact cggctttcag ggcgtacaga tcggggagct ttttcacacc ctgtcccttt
     7921 agggcctttg ccgcagcttc atacaaaatc aacgtgcttt catgctcacg ccggaatttt
     7981 gccttatccg ctgcattgcg gtattccata gccacgggcc agagctgctt gtaggtagaa
     8041 atattcttta tcagcaccgc catatccgca agccggtgtt ccatagcttt gagggtagcg
     8101 gcggcctcgt cgctggcggc ggtgatctcg gccactttgc tttccaaatc cgggtaggtg
     8161 tctatcccat gttcagtcag gaaattcaaa gtctttgcgg cctgcttcaa attgtggagc
     8221 ttcgcccacc tctcatagcc tgccgactgc tgggccttaa tgttgttttc cagatcaatc
     8281 cgcaaagaaa tccccttgcg ctctttgggc gctctggtga taacgcggcc tttgatacgc
     8341 tctttgatgg cttcctcggt gtaggcttcc cccaatgtct tgcagcgggt aaagcgttcc
     8401 tgtccgggag cgcggaaaga aataaacttt cccggcttga tctcatagcc ctgcgcctgc
     8461 atgagccgca ggaaatcatc aaaatctttt gcctgcggga tagcggcgtc aatggctgct
     8521 ttgagcttcg ctttccagct cgtccctttc cgctgggcgt cccactcggc atagctcttg
     8581 cccttactct ggccgggctt caccacggac aatccgtttt ccttgcacag cctgtcgctg
     8641 gtgcgccgga tataggcata gctctgtttg ttggaaatgt acttgcgctg atttaccata
     8701 tccacggcac agaaaataat gtgattgtgg acgtggccct tatcaatatg ggtagtcagc
     8761 acatagggat atttcccttg cagcacttcc tcggcaagct gcttcccgat ctcatgggcc
     8821 tgttccggcg tggcttcgcc gggggcaaag gattgtatca ggtggtggcc cagattattg
     8881 cccttttggt atgcctgcgc cagcagcatt tcaaattcaa tgtccgctgt ttcataagag
     8941 caggcaaagg aggccaccag cagcttgccg tcagttttgt ccgggttctc gatgtagtca
     9001 agggcttttt tcagcgttga cttgatagga tgtatctttg taactgccat atctgcgcca
     9061 gcgccccctt tatatcctcg atgtcctgtg cgtacaccgg ccccataccg ttcagcctct
     9121 ttgcaatctg attgacgttg acgccgatct tctgtatctc ggcggtctgc gcccggatgt
     9181 cgctggtgtc catgttgacg atatagccgt caatgagcat cttccgggcg taggctgaaa
     9241 agttcttcgt atgcagcagc gccattttct gttcaatcat agcccgttcc tccggcgtca
     9301 cagggacgcg cagcacgatt tttcgctttc tgtttgccat gcttcaccgt cctttccatt
     9361 caggggtttg gggatttccc caacaagcaa aacggacgcg gcccggcagg gacggggcag
     9421 gccgtttttc cgggagtggc tacactccct atgcttgcta cgttactgtt tctccactaa
     9481 caagacgttt ccaaagcccc aaactacccg caaaatagcc ctctggaaag aaaaaagtgc
     9541 aaaaaaatag aagctacgct gtgcagctcc cgctaaaagt aaaacagagg atgccagtta
     9601 cacatcctcc gtttcattct tcttcggctt ttcaattagt atggcgctgt caatcgcgcc
     9661 ctcgatgatc ggcaggtatt cttcggggca gagtttcagc ttgtggctga ccctttgccg
     9721 cagttcgctt tcctcccgca tgatctccgg gttaaagtag cgttccacag gaagcccgca
     9781 ggctttaata agctgtatga caaccggcag actgggaatg gccccgtcgt tttcgatgtt
     9841 ggcaagatag cgccagtcaa tatttatttt ctctgccatt gctttgcgcg aaacgcgctt
     9901 tgcttgccgg gccgctttca catccgcgcc gaaagtttca aagccgggac aatcttcaat
     9961 attcgccata tcgcacctcc cacttacatt gtatatttca tactctgccc gtggaatgtt
    10021 ggtatatgca cctttcttaa agtttatatt tcacattttg tttcttttat tcttcgagca
    10081 aaagaattat aatgtaccct gtggaggtgt actatggact acatgacgtt gaaagaggca
    10141 ggcgagaaat ggggtgtgcc cccacgatgg ataaactact attgtgctgc gggacgcatc
    10201 cccggcgctg taaagatggc gacgatctgg ctcattccca aaactgcgga aaagccgatt
    10261 gacaggcgta caaagaaagg aaaggcggtt actgaatagt ataatgaaac cggcgcattt
    10321 tggatatggt tttgaagaga gagaaagcat ggtattttgt cacggaaaaa ctataagatg
    10381 atagatggca ggctgctcca gaccgataaa aagtattctc atctgaaaca gaaagaaaag
    10441 atttacacat ggatgtatga agaagcgaaa ctttatcatg acagaaatgg aaaatgcccg
    10501 aaacaaagac gaggaagctg ctgctgtatc agccgtatat ggtagaattg aaaaggccgg
    10561 catctggatt ctttatggtg aagtctccag acattggata actgctggtc taatgcgcct
    10621 ttgagtatgg ggtgattgat tttaataccg gggaggtacg gctttttgag gaaaatattc
    10681 tgggatttac atttggcgat tattacattt cctgtaactg caaggacacg gatgatgaag
    10741 atatgaggaa tatagacttg ctgattttct actgtcttga acggtattag gactgaatct
    10801 gctgcgcgga gtgcggcaag agcgaccgga gggagtacac acaggccctg cctgtgtgaa
    10861 aagccatacc gcaaggtgca ttcgcaaaaa agaggccgcg cattttgctg aggcttgggg
    10921 tgtccccaac aagcaaaacg agaacgccgc aggcgggcaa gtggtggatc agaatatccg
    10981 taaaggatat tctgatccat tgcttgccag tattatcggg atgttttgac aaccgctgta
    11041 atcgaaacat cccaaacatt aagaaggtgt taattattat tatcttgatt taattcgttt
    11101 aaaccaataa tatagataca tacaccatga aaagaagcga gtatcccaat gacggatgat
    11161 taaaatccga aaagaaatcg ctttgaaact acagggaaac tacagactgt tatgttatct
    11221 tcttaaaatg gagggatttt tatgtcgata cgaattctac ttgtcgagga tgatgatcat
    11281 atctgtaata cagtaagggc gtttctggct gaggcaggat atcaggtgga tgcctgcaca
    11341 gatggaaatg aggcatacac caagttttac gaaaacactt atcaactggt tattcttgat
    11401 attatgctgc ccggtatgaa cgggcatgaa cttttgcgtg aatttcgtgc gaaaaatgat
    11461 actcccattc tgatgatgac agccctgtcg gatgacgaaa accaaatccg ggcgtttgat
    11521 ctagaggcag acgactatgt aacaaagcca ttcaagatgc agattttact aaagcgggtg
    11581 gaagccctgc tgcggcgcag cggtgcgctg gcaaaggaaa tccgtgtcgg caggctgaca
    11641 cttctgccgg aggatttcac ggtactttgt gacggtacag agctgcccct gacacgaaaa
    11701 gaatttgaaa tccttttgct gctggtgcag aacaaaggca gaaccttaac gcatgaaatc
    11761 attttgtcac gtatatgggg atatgacttt gagagtgatg gcagcacagt ccacactcat
    11821 atcaaaaatt tgcgggccaa gctgccggaa aatatcatca aaaccattcg cggtgtagga
    11881 taccgattgg aggaatcata ataatggaaa gaaaagggat tttcattaag gttttttcct
    11941 atacgatcat tgtcctgcta ctgcttgtcg gtgtaacagc aacactgttt gcacagcaat
    12001 ttgtgtctta tttcagagtg atggaattac agcaaacagt aaaatcctat cagccattgg
    12061 tggaactgat tcagaatagc gataggcttg atattcaaga ggtggcaggg ctgtttcact
    12121 acaataacca atcctttgag ttttatattg aagataaaga gggaagcgta ctctatgcca
    12181 caccaaatgc caatacatca aatagtttta gacccgactt tctttatgtg gtacatagag
    12241 atgataatat ttcgattgtt gctcaaagca aggcaggtgt gggattgctt tatcaagggc
    12301 tgacaattcg gggaattgtt atgattgcga taatggttgt attcagcctt ttatgcgcgt
    12361 atatctttgc gcggcaaatg acaacgccga tcaaagcctt agcggacagt gcgaataaaa
    12421 tggcaaacct gaaagatgta ccgccgccgc tggagcgaaa ggatgagctt ggcgcactgg
    12481 ctcatgatat gcattccatg tatgtcaggc tgaaagaaac catcgcaagg ctggaggatg
    12541 aaatcgcaag ggaacatgag ttggaggaaa cacagcgata tttctttgcg gcagcttctc
    12601 atgagctaaa aacgcccatc gcggctacaa gcgttctgtt ggagggaatg cttgaaaata
    12661 tcggtgacta caaagatcat tctaagtatc tgcgcgaatg catcaaaatg atggataggc
    12721 agggcaaaat catttccgaa atactggagc ttgtcagcct gaatgatggg agaatcgtac
    12781 ccatagctga accgttggac atagggcgca cggttgccga gttgctgccc gattttcaaa
    12841 ccttggcaga ggcaaacaac cagcggttcg tcacagatat tccagccggg caaattgtcc
    12901 tgtccgatcc gaggctgctc caaaaggcac tatccaatgt catattgaat gcagttcaga
    12961 acacgccgca gggaggcgag gtacggatat ggagtgagcc tggtgctgaa aaatgccgcc
    13021 tttttgtttt gaacatgggc gttcacattg atgatactgc gcttccaagg ctgttcaccc
    13081 cattctatcg cattgatcag gcgcgaagca gaaaaagtgg gcgaaacggt ttaggacttg
    13141 ccatcgtaca aaaaacgctg gatgccatga gcctccagta tgcgctggaa aacacctcgg
    13201 atggcgtttt gttctggctg gatttaccgc tcacatcaac attgtaaata tttaaaactt
    13261 aaatgatttt gaccgacagg tataaccctg ccggtctttt tttgctgcta caggaaaact
    13321 acagactggc tacagggaaa gtacagatgc gcttgccata ataacaatcg taccagccac
    13381 aaatcgtagt tttattgcaa aggaggcatt cgatcaaatg gaaaaaagca actatcattc
    13441 caatgcggat catcacaaac ggcatatgaa acaatccgtg gaaaagcggg cttttctatg
    13501 tgcgttcatt atttcgttca cagtctgcac gctgtttttg gggcggagac tggcttccgt
    13561 attggaggca acacagatac cgcccatccc tgcaactcat acaggcagca gcactgacgt
    13621 agtggagaat ttggaggaaa acgctcttgc caccgccaaa gaacagggag atgaacagga
    13681 atggagcctg attttagtga acaggcagaa ccccatcccc gcacagtacg atgtggagct
    13741 tgagcaacta tcaaatggtg agcggataga tattcggatt tctccctatc ttcaagattt
    13801 gtttgatgcc gcaagaactg atggagttta cccgattgtc gcatccggat accgaacaac
    13861 agaaaaacag caagaaatta tggatgaaaa aattgccgaa tataaggcga aaggctacac
    13921 ctctgcacag gctaaagcgg aagcagaaac ttgggtggcc gtgccgggaa cgagcgagca
    13981 tcagcttggt cttgctgtgg atatcaatgc ggacggaatt cattcaacag gcaacgaggt
    14041 ttatagatgg ctggatgaaa acagctatcg ttttggtttt attcgtcgct acccaccaga
    14101 caagacagag ataaccggtg tgagcaacga gccgtggcat taccgatatg ttggcatcga
    14161 agctgccaca gagatgtaca accaaggggt ttgccttgag gaatatttaa aaccagaaaa
    14221 atgagaaaag gatgttatgg acagaaaaag attgacacag cgtttcccgt tcctgcttcc
    14281 aatgagacgg gcgcagagaa aaatgtgctt ttatgcggga atgagatttg acggctgtcg
    14341 ctatgcgcag acgatagggg aaaaatcgct ttcccatttg ctctttgaaa cggattgcgc
    14401 attatacaac cacaataccg gatttgacat gatataccag gaaaacaagg tgttcaactt
    14461 aaagctggca gcaaagacct taaacggctt attgataaga ccgggggaaa ccttttcttt
    14521 ctggtggctg gtacgccatg cggacaaaga taccccctat aaagacggcc ttacggtgac
    14581 caatggtaaa ctcaccacca tgtcgggcgg cggtatgtgc cagatgagca atttactatt
    14641 ttggatgttc ctgcatacgc cattgacaat tatccagcgc agaggtcacg aagtaaagga
    14701 gtttccagag ccaaacagtg acgagattaa aggggtggat gcaaccattt cagagggctg
    14761 gattgattta aaagtgcgaa acgataccga ctgcacctac caaatatgag tgaccttaga
    14821 tgatgagaaa atcatcggtc aggtgtccgc cgacaaagag ccccaagcat tatacaaaat
    14881 tacaaatggc agtatccagt atgtccgtga aagtggcggg atttatgaat atgcccaggt
    14941 taaacggatg caagttgcct taggtaccgg ggaaataata gattgcaagc tgctttatac
    15001 aaacaaatgc aaaatctgtt atcccctccc ggaaagtgtg gatattcagt ctaatggtga
    15061 taagtcaaga tgaaatttaa gattttc
//
LOCUS       DACDLM010000239         4157 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.guided.137, whole genome shotgun sequence.
ACCESSION   DACDLM010000239 DACDLM010000000
VERSION     DACDLM010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4157
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.guided.137"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..410
                     /locus_tag="IV356_003090"
     CDS             <1..410
                     /locus_tag="IV356_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP9016672.1"
                     /translation="IVQIFEENIGISLTRYEIMMRLKEENPLLQSSLQEKLQIDQGAV
                     TRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEHCEMDHKDTGSVLSPAFSDV
                     EMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            394..1023
                     /locus_tag="IV356_003091"
     CDS             394..1023
                     /locus_tag="IV356_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAP9016673.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            1377..2855
                     /gene="msr"
                     /locus_tag="IV356_003092"
     CDS             1377..2855
                     /gene="msr"
                     /locus_tag="IV356_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAP9016674.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            2902..3348
                     /locus_tag="IV356_003093"
     CDS             2902..3348
                     /locus_tag="IV356_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAP9016675.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(3547..4062)
                     /locus_tag="IV356_003094"
     CDS             complement(3547..4062)
                     /locus_tag="IV356_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP9016676.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
BASE COUNT         1361 a          704 c          864 g         1228 t
ORIGIN      
        1 aaatcgtcca gatctttgaa gaaaatatcg gtataagtct tactagatac gagatcatga
       61 tgagactgaa agaagaaaat ccattgctac aaagcagttt gcaagaaaag ttgcagattg
      121 atcaaggagc agttactcgt catctgaagg tattggaagc aaatggctat gtttcgcgtc
      181 agagaaatcc tcagaacaac cgggaagtgt atgtagcgct aacagaaaaa gcccagaaga
      241 aaatcgagca ttgtgaaatg gaccataaag atacaggttc cgtgctatcc ccggctttca
      301 gcgatgtaga aatgaaacaa tttctaacac ttttagataa attgaatacc caactttgca
      361 atataacaac agaaacgaaa gaggttaata ataatggaac aaaaaaatga tttttcaaca
      421 attatgactg gtagaagatc cgttcgcgta tatgatgaaa catacaaaat cccacacgaa
      481 gaaatgctgg aaatgatcaa agaagcgacg actgcacctt cttctgtcaa tatgcaacca
      541 tggcgctttg tggtcgctga aagcgaggaa gcaaaagaaa tcttgcgtcc tttgatccgt
      601 ttcaatacga gacaaaatga tacttcttct gcaatggtca tgatttttgg cgatatgcaa
      661 tgttacgaat atggcgaaga aatctataac caagcttacg aatcagggaa gatgccaaaa
      721 gaagtcagag atcaacaatt agctgcgatc attccttatt acaagagttt ttcaagagaa
      781 gaaatgaacg atgtagtcaa agtcgattct agcttagcgg ctatgcaatt catgttagtt
      841 gcgcgtgatc atggctatga aacaaatcca attggtggat tcgaagcaga tcagttggca
      901 gaggcatttg gtttggataa agaccgttat gttccagtta ttattttatc aataggaaaa
      961 gcggtagaag aaggttacga gtctgttcgt ttagcaccag aaaagatcac tacgttcgaa
     1021 taaaaggttt tcagttacta ttcagtagct attgcttttt ttgaatcgtg tgtggtaacc
     1081 taataaaaaa ggaggtcgga aaaatgactg catcgatgaa attacgtttc gaacttttga
     1141 ataacaacta aataaattca aaagacatgt ataaacaaca atttcatgga tggagtatgt
     1201 ccattttttc gaacgacagt agaataggtg aaagctatga cagatttggt gatttagtca
     1261 tagttatttc gttcagagta ggaaaagatg tgatgcagtt tttttgcaaa cagatttttc
     1321 tgctcttttt tagtatcgat aattgttgtt ttacatgaaa taggagtgta aaacatatgg
     1381 aaaatttagc agtaaatata acaaatctac aagtcagctt tggcaaccag ctagaactat
     1441 ctattgattc tcttcgtgtc tatcagcaag atcgtatagg gatcatagga gaaaatggtg
     1501 tcggtaaatc gactttgctc aaactaatag ccggtgaact ttttcccgat catgggaaaa
     1561 tccaaacaga gatcaccttc aactacctgc ctcaattaac ctatctcgct gaagcaaagg
     1621 acctaaattt ggaattagcc agtcatttcc agttaagact ggaagaaact tcagagcgga
     1681 aatggagcgg aggggaagaa cgaaagatcg agttgatacg tcttctttct tcttatgaac
     1741 aagggatgct tctagacgag ccaacaaccc atctagatag aaaaagtatt gatcgactga
     1801 ttgaagagct tcgttattat tatggtacgc tggtttttgt tagtcatgat cgctattttc
     1861 tagatgagct agcatcgaaa atctgggaag taaaagacgg agaaatccga gagttttcgg
     1921 ggaattatag tgcctatctc actcaaaagg aattggagaa aaagactcag ctacgagaag
     1981 cagagtcgat catgaaagag aaaaaacgat tggaaaaatc gatccaagaa aagaaaaaac
     2041 aagcggaaaa gttggaaaaa gtgtccagta aaaagaaaaa gcaacaaatc agaccggatc
     2101 ggttgtcttc ctctaaacaa aaagacagtg tacaaaaagc catccaaaag aatgcgaaaa
     2161 cattagagag aagactccaa aaaataggag aaacaaccaa gccgcagcag atgaaacaaa
     2221 tccgttttcc agtaccaaaa tctcttgaac tccacagccg ctatcccatc atgggacaaa
     2281 atgtccaatt ggaaagaagt gggagaacat tactggtaaa tggtgatttt cagttttctt
     2341 taggtaaaaa aatcgcgatt gtcggtgaaa atggttcagg taagacaacc ttattagaac
     2401 atatccgcaa acaaggagaa ggaatccttc tctctccgaa agtaagcttt caagtatatc
     2461 agcaaaaggg ttatcaaatg acatctgaag aatccatcat tcgttttgtc atgagacaaa
     2521 cagagttttc agaatcgctt gtccgtagtt tgctgaatca cttagggttt gctcaggaaa
     2581 ctttgacgaa accgttatgt acattaagtg ggggagaagc gacccgtctg acgattgctt
     2641 tgctttttac taagccaagt aatgtgttgc tgttagatga accgactaat tttattgata
     2701 tggcaacgat cgaagcttta gagaagctaa tgcaaatata tccgggaacg attttgttta
     2761 cttctcatga ttcttacttt gtcgagcgta cggctgatga agtttatgaa ataaaagggc
     2821 agaaaataaa aaaagtactt acgagaaatt tttaaatgtg ctacgatgat tttcgtgaca
     2881 aatttaaagg agtggtacag attgcctaca aataaaaaag aaggaataat ttttacaaca
     2941 atgatgtgtt ttttgatggt cttggggatg agcgcgtata atttatggct gcatcaagat
     3001 cttcatttat caagtttgtt gattggtcta gtgcctggat tcgtggtggc tttcattttg
     3061 gatgtcttca tcatcggtgt gctggcgaaa aaaattgcct ttaaactacc agtaaatcca
     3121 gaaagcaagg tccaaatgat cttaactatt tcatgcttga tggttttagg aatggtgaca
     3181 tgtatgtctt tattcggtgt gatcatggaa caaggaatac ctgatcaatt attctctgct
     3241 tatatgaatg cttggaaaat gaatgtgatt gccgctttac cgttgcagtt gatcatcgtt
     3301 ggcccgcttt caagaagtgt gctaaaagca attcaaagta atgaatgatg gaacactgtt
     3361 atttgaaaaa aggccttggc atgctttttg tcatagtctc ttgaatgcag ttctagaaaa
     3421 atagtgatcc gaacgatagg ttttggcctg tcgttcggat cgctttttct tttccaactg
     3481 tattgctctt ttattgaaga taatttgctc ttcaatagat atttctagaa aggttctgtt
     3541 tatcccttac tcaaaaaact gctgcatttg ttctcttact tgctgacacc attggagttc
     3601 ctgctgacaa agcataattc tgcgctggat cacaacataa cgtccaaatt cttgtttctt
     3661 gtctagcgag aggtcattca attttttttg atttttttgc atgattttgt tcagctgttg
     3721 ttctctagtg aatagcagtc cagtagctgt tgttttatcg agcgtcgaaa aagcatagat
     3781 ttttgctaga aattcatctt tttgcgtagg agcgggagtt tcctctttga tccattcctc
     3841 tacaagagca cgtccttcat cagtcaagtg gtagatcttt ttttgagagt gctcgtcttt
     3901 gtccaaaacg gtcacataac cctgctggtc taacttggca agcgttgtat agatctgact
     3961 gtgatgggct tcccaaaaaa ttgtgatcag ctgcttcaat tcatacccag aacgtggttt
     4021 ggataaaagc acgcataata atatataggc taaagtattc ataaaaatcc tacctctcgt
     4081 cttattttct ttattatatc acagtaaagt ttccacgttt tacatgtgca tatttacatg
     4141 taaaataaat catgtat
//
LOCUS       DACDLM010000240         3981 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.guided.142, whole genome shotgun sequence.
ACCESSION   DACDLM010000240 DACDLM010000000
VERSION     DACDLM010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3981
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.guided.142"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            22..1941
                     /gene="tet(M)"
                     /locus_tag="IV356_003095"
     CDS             22..1941
                     /gene="tet(M)"
                     /locus_tag="IV356_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019117172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HAP9016677.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2039..3412
                     /gene="tet(L)"
                     /locus_tag="IV356_003096"
     CDS             2039..3412
                     /gene="tet(L)"
                     /locus_tag="IV356_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HAP9016678.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
BASE COUNT         1258 a          614 c          820 g         1289 t
ORIGIN      
        1 ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc tcatgttgat
       61 gcaggaaaaa ctaccttaac agaaagctta ttatataaca gtggagcgat tacagaatta
      121 ggaagcgtgg acaaaggtac aacgaggacg gataatacgc ttttagaacg tcagagagga
      181 attacaattc agacaggaat aacctctttt cagtgggaaa atacgaaggt gaacatcata
      241 gacacgccag gacatatgga tttcttagca gaagtatatc gttcattatc agttttagat
      301 ggggcaattc tactgatttc tgcaaaagat ggcgtacaag cacaaactcg tatattattt
      361 catgcactta ggaaaatggg gattcccaca atctttttta tcaataagat tgaccaaaat
      421 ggaattgatt tatcaacggt ttatcaggat attaaagaga aactttctgc cgaaattgta
      481 atcaaacaga aggtagaact gtatcctaat atgtgtgtga cgaactttac cgaatctgaa
      541 caatgggata cggtaataga gggaaacgat gaccttttag agaaatatat gtccggtaaa
      601 tcattagaag cattggaact cgaacaagag gaaagcataa gatttcagaa ttgctccttg
      661 taccctgttt atcatggaag cgcaaaaagc aacataggga ttgagcagct tatagaagtg
      721 ataacgaata aattttattc atcaacatac agaaagaagt ctgaactttg cggaaatgtc
      781 ttcaaaattg aatattcgga agaaagacaa cgtcttgcat atgtacgcct ttatggcgga
      841 atcctgcatt tgcgggattc ggttagaata tcggaaaagg aaaaaataaa aattacagaa
      901 atgtatactt caataaatgg tgaattatgt aaaattgata aggcttattc cggggaaatt
      961 gttattttgc aaaatgagtt tttgaagcta aatagtgttc ttggagatac aaagctattg
     1021 ccacagagag agagaattga aaatccgctc cctctgctgc aaacaactgt tgaaccgagc
     1081 aaacctcaac aaagggaaat gttacttgat gcacttttag aaatctccga cagtgacccg
     1141 cttctacaat attatgtgga ttctacgaca catgaaatta tactttcttt cttagggaaa
     1201 gtacaaatgg aagtgattag tgcactgttg caagaaaagt atcatgtgga gatagaacta
     1261 aaagagccta cagtcattta tatggagaga ccgttaaaaa atgcagaata taccattcac
     1321 atcgaagtgc cgccaaatcc tttctgggct tccattggtt tatctgtatc accgcttccg
     1381 ttgggaagtg gaatgcagta tgagagctcg gtttctcttg gatacttaaa tcaatcattt
     1441 caaaatgcag ttatggaagg gatacgctat ggttgcgaac aaggattata tggttggaat
     1501 gtgacggatt gtaaaatctg ttttaagtat ggcttatact atagccctgt tagtacccca
     1561 gcagattttc ggatgcttgc tcctattgta ttggaacaag tcttaaaaaa agctggaaca
     1621 gaattgttag agccatatct tagttttaaa atttatgcgc cacaggaata tctttcacga
     1681 gcatacaacg atgctcctaa atattgtgcg aacatcgtag acactcaatt gaaaaataat
     1741 gaggtcattc ttagtggaga aatccctgct cggtgtattc aagaatatcg tagtgattta
     1801 actttcttta caaatggacg tagtgtttgt ttaacagagt taaaagggta ccatgttact
     1861 accggtgaac ctgtttgcca gccccgtcgt ccaaatagtc ggatagataa agtacgatat
     1921 atgttcaata aaataactta gtgtatttta tgttgttata taaatatggt ttcttgttaa
     1981 ataagatgaa atatttttta ataaagattt gaattaaagt gtaaaggagg aattaattat
     2041 gaagtgtaat gaatgtaaca gggttaaata caaccaaatt ttaatttggc tttgcgtttt
     2101 atcttttttt agcgtattaa atgaaatggt tttgaacgtc tcattacctg atattgcaaa
     2161 tgattttaat aaaccacctg cgagtacaaa ctgggtgaac acagccttta tgttaacctt
     2221 ttccattgga acagctgtat atggaaagct atctgatcaa ttaggcatca aaaggttact
     2281 cctatttgga attataataa attgtttcgg gtcggtaatt gggtttgttg gccattcttt
     2341 cttttcctta cttattatgg ctcgttttat tcaaggggct ggtgcagctg catttccagc
     2401 actcgtaatg gttgtagttg cgcgctatat tccaaaggaa aataggggta aagcatttgg
     2461 tcttattgga tcgatagtag ccatgggaga aggagtcggt ccagcgattg gtggaatgat
     2521 agcccattat attcattggt cctatcttct actcattcct atgataacaa ttatcactgt
     2581 tccgtttctt atgaaattat taaagaaaga agtaaggata aaaggtcatt ttgatatcaa
     2641 aggaattata ctaatgtctg taggcattgt attttttatg ttgtttacaa catcatatag
     2701 catttctttt cttatcgtta gcgtgctgtc attcctgata tttgtaaaac atatcaggaa
     2761 agtaacagat ccttttgttg atcccggatt agggaaaaat atacctttta tgattggagt
     2821 tctttgtggg ggaattatat ttggaacagt agcagggttt gtctctatgg ttccttatat
     2881 gatgaaagat gttcaccagc taagtactgc cgaaatcgga agtgtaatta ttttccctgg
     2941 aacaatgagt gtcattattt tcggctacat tggtgggata cttgttgata gaagaggtcc
     3001 tttatacgtg ttaaacatcg gagttacatt tctttctgtt agctttttaa ctgcttcctt
     3061 tcttttagaa acaacatcat ggttcatgac aattataatc gtatttgttt taggtgggct
     3121 ttcgttcacc aaaacagtta tatcaacaat tgtttcaagt agcttgaaac agcaggaagc
     3181 tggtgctgga atgagtttgc ttaactttac cagcttttta tcagagggaa caggtattgc
     3241 aattgtaggt ggtttattat ccataccctt acttgatcaa aggttgttac ctatggaagt
     3301 tgatcagtca acttatctgt atagtaattt gttattactt ttttcaggaa tcattgtcat
     3361 tagttggctg gttaccttga atgtatataa acattctcaa agggatttct aaatcgttaa
     3421 gggatcaact ttgggagaga gttcaaaatt gatccttttt ttataacagg aattcaaatc
     3481 tttttgttcc attaaagggc gcgattgctg aataaaagat acgagagacc tctcttgtat
     3541 cttttttatt ttgagtggtt ttgtccgtta cactagaaaa ccgaaagaca ataaaaattt
     3601 tattcttgct gagtctggct ttcggtaagc tagacaaaac ggacaaaata aaaattggca
     3661 agggtttaaa ggtggagatt ttttgagtga tcttctcaaa aaatactacc tgtcccttgc
     3721 tgatttttaa acgagcacga gagcaaaacc cccctttgct gaggtggcag agggcaggtt
     3781 tttttgtttc ttttttctcg taaaaaaaag aaaggtctta aaggttttat ggttttggtc
     3841 ggcactgccg acagcctcgc agagcacaca ctttatgaat ataaagtata gtgtgttata
     3901 ctttacttgg aagtggttgc cggaaagagc gaaaatgcct cacatttgtg ccacctaaaa
     3961 aggagcgatt tacatatgag t
//
LOCUS       DACDLM010000241         3981 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.guided.143, whole genome shotgun sequence.
ACCESSION   DACDLM010000241 DACDLM010000000
VERSION     DACDLM010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3981
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.guided.143"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            22..1941
                     /gene="tet(M)"
                     /locus_tag="IV356_003097"
     CDS             22..1941
                     /gene="tet(M)"
                     /locus_tag="IV356_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019117172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HAP9016679.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2039..3412
                     /gene="tet(L)"
                     /locus_tag="IV356_003098"
     CDS             2039..3412
                     /gene="tet(L)"
                     /locus_tag="IV356_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HAP9016680.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
BASE COUNT         1257 a          614 c          821 g         1289 t
ORIGIN      
        1 ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc tcatgttgat
       61 gcgggaaaaa ctaccttaac agaaagctta ttatataaca gtggagcgat tacagaatta
      121 ggaagcgtgg acaaaggtac aacgaggacg gataatacgc ttttagaacg tcagagagga
      181 attacaattc agacaggaat aacctctttt cagtgggaaa atacgaaggt gaacatcata
      241 gacacgccag gacatatgga tttcttagca gaagtatatc gttcattatc agttttagat
      301 ggggcaattc tactgatttc tgcaaaagat ggcgtacaag cacaaactcg tatattattt
      361 catgcactta ggaaaatggg gattcccaca atctttttta tcaataagat tgaccaaaat
      421 ggaattgatt tatcaacggt ttatcaggat attaaagaga aactttctgc cgaaattgta
      481 atcaaacaga aggtagaact gtatcctaat atgtgtgtga cgaactttac cgaatctgaa
      541 caatgggata cggtaataga gggaaacgat gaccttttag agaaatatat gtccggtaaa
      601 tcattagaag cattggaact cgaacaagag gaaagcataa gatttcagaa ttgctccttg
      661 taccctgttt atcatggaag cgcaaaaagc aacataggga ttgagcagct tatagaagtg
      721 ataacgaata aattttattc atcaacatac agaaagaagt ctgaactttg cggaaatgtc
      781 ttcaaaattg aatattcgga agaaagacaa cgtcttgcat atgtacgcct ttatggcgga
      841 atcctgcatt tgcgggattc ggttagaata tcggaaaagg aaaaaataaa aattacagaa
      901 atgtatactt caataaatgg tgaattatgt aaaattgata aggcttattc cggggaaatt
      961 gttattttgc aaaatgagtt tttgaagcta aatagtgttc ttggagatac aaagctattg
     1021 ccacagagag agagaattga aaatccgctc cctctgctgc aaacaactgt tgaaccgagc
     1081 aaacctcaac aaagggaaat gttacttgat gcacttttag aaatctccga cagtgacccg
     1141 cttctacaat attatgtgga ttctacgaca catgaaatta tactttcttt cttagggaaa
     1201 gtacaaatgg aagtgattag tgcactgttg caagaaaagt atcatgtgga gatagaacta
     1261 aaagagccta cagtcattta tatggagaga ccgttaaaaa atgcagaata taccattcac
     1321 atcgaagtgc cgccaaatcc tttctgggct tccattggtt tatctgtatc accgcttccg
     1381 ttgggaagtg gaatgcagta tgagagctcg gtttctcttg gatacttaaa tcaatcattt
     1441 caaaatgcag ttatggaagg gatacgctat ggttgcgaac aaggattata tggttggaat
     1501 gtgacggatt gtaaaatctg ttttaagtat ggcttatact atagccctgt tagtacccca
     1561 gcagattttc ggatgcttgc tcctattgta ttggaacaag tcttaaaaaa agctggaaca
     1621 gaattgttag agccatatct tagttttaaa atttatgcgc cacaggaata tctttcacga
     1681 gcatacaacg atgctcctaa atattgtgcg aacatcgtag acactcaatt gaaaaataat
     1741 gaggtcattc ttagtggaga aatccctgct cggtgtattc aagaatatcg tagtgattta
     1801 actttcttta caaatggacg tagtgtttgt ttaacagagt taaaagggta ccatgttact
     1861 accggtgaac ctgtttgcca gccccgtcgt ccaaatagtc ggatagataa agtacgatat
     1921 atgttcaata aaataactta gtgtatttta tgttgttata taaatatggt ttcttgttaa
     1981 ataagatgaa atatttttta ataaagattt gaattaaagt gtaaaggagg aattaattat
     2041 gaagtgtaat gaatgtaaca gggttaaata caaccaaatt ttaatttggc tttgcgtttt
     2101 atcttttttt agcgtattaa atgaaatggt tttgaacgtc tcattacctg atattgcaaa
     2161 tgattttaat aaaccacctg cgagtacaaa ctgggtgaac acagccttta tgttaacctt
     2221 ttccattgga acagctgtat atggaaagct atctgatcaa ttaggcatca aaaggttact
     2281 cctatttgga attataataa attgtttcgg gtcggtaatt gggtttgttg gccattcttt
     2341 cttttcctta cttattatgg ctcgttttat tcaaggggct ggtgcagctg catttccagc
     2401 actcgtaatg gttgtagttg cgcgctatat tccaaaggaa aataggggta aagcatttgg
     2461 tcttattgga tcgatagtag ccatgggaga aggagtcggt ccagcgattg gtggaatgat
     2521 agcccattat attcattggt cctatcttct actcattcct atgataacaa ttatcactgt
     2581 tccgtttctt atgaaattat taaagaaaga agtaaggata aaaggtcatt ttgatatcaa
     2641 aggaattata ctaatgtctg taggcattgt attttttatg ttgtttacaa catcatatag
     2701 catttctttt cttatcgtta gcgtgctgtc attcctgata tttgtaaaac atatcaggaa
     2761 agtaacagat ccttttgttg atcccggatt agggaaaaat atacctttta tgattggagt
     2821 tctttgtggg ggaattatat ttggaacagt agcagggttt gtctctatgg ttccttatat
     2881 gatgaaagat gttcaccagc taagtactgc cgaaatcgga agtgtaatta ttttccctgg
     2941 aacaatgagt gtcattattt tcggctacat tggtgggata cttgttgata gaagaggtcc
     3001 tttatacgtg ttaaacatcg gagttacatt tctttctgtt agctttttaa ctgcttcctt
     3061 tcttttagaa acaacatcat ggttcatgac aattataatc gtatttgttt taggtgggct
     3121 ttcgttcacc aaaacagtta tatcaacaat tgtttcaagt agcttgaaac agcaggaagc
     3181 tggtgctgga atgagtttgc ttaactttac cagcttttta tcagagggaa caggtattgc
     3241 aattgtaggt ggtttattat ccataccctt acttgatcaa aggttgttac ctatggaagt
     3301 tgatcagtca acttatctgt atagtaattt gttattactt ttttcaggaa tcattgtcat
     3361 tagttggctg gttaccttga atgtatataa acattctcaa agggatttct aaatcgttaa
     3421 gggatcaact ttgggagaga gttcaaaatt gatccttttt ttataacagg aattcaaatc
     3481 tttttgttcc attaaagggc gcgattgctg aataaaagat acgagagacc tctcttgtat
     3541 cttttttatt ttgagtggtt ttgtccgtta cactagaaaa ccgaaagaca ataaaaattt
     3601 tattcttgct gagtctggct ttcggtaagc tagacaaaac ggacaaaata aaaattggca
     3661 agggtttaaa ggtggagatt ttttgagtga tcttctcaaa aaatactacc tgtcccttgc
     3721 tgatttttaa acgagcacga gagcaaaacc cccctttgct gaggtggcag agggcaggtt
     3781 tttttgtttc ttttttctcg taaaaaaaag aaaggtctta aaggttttat ggttttggtc
     3841 ggcactgccg acagcctcgc agagcacaca ctttatgaat ataaagtata gtgtgttata
     3901 ctttacttgg aagtggttgc cggaaagagc gaaaatgcct cacatttgtg ccacctaaaa
     3961 aggagcgatt tacatatgag t
//
LOCUS       DACDLM010000242         3758 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.guided.147, whole genome shotgun sequence.
ACCESSION   DACDLM010000242 DACDLM010000000
VERSION     DACDLM010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3758
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.guided.147"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            <1..1859
                     /locus_tag="IV356_003099"
     CDS             <1..1859
                     /locus_tag="IV356_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP9016681.1"
                     /translation="KKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKTSLLNIIAGID
                     SSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVRAYEEALIELG
                     ENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKISTLSGGQKKRV
                     SLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDRYFLDRVANRI
                     FELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMRAGVQARGTKQ
                     QARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRINDQTLLEHLDLL
                     IQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQENEEMAPDKR
                     MIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEKRRLFLLKLLI
                     QQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVADKLLVFQGNG
                     KQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKEWETIEDEIAE
                     LEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSEWVED"
     gene            1871..2818
                     /locus_tag="IV356_003100"
     CDS             1871..2818
                     /locus_tag="IV356_003100"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAP9016682.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            2838..3365
                     /locus_tag="IV356_003101"
     CDS             2838..3365
                     /locus_tag="IV356_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP9016683.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(3428..>3758)
                     /locus_tag="IV356_003102"
     CDS             complement(3428..>3758)
                     /locus_tag="IV356_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAP9016684.1"
                     /translation="LGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWL
                     CVVAAVPLYHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMY
                     FSVLFFT"
BASE COUNT         1317 a          660 c          819 g          962 t
ORIGIN      
        1 tcaaaaaaac ttatggtgaa aaagatttgt ttgaccagat ttcttttttg gtccacgaaa
       61 aagaccgtat cgggttgatt gggacgaacg ggacgggtaa aacaagtctc ttaaatatta
      121 ttgccggtat cgatagcagc gacggtgatc ggcaaacagt gttttatcca actgattacc
      181 gtattggtta tctttctcaa gcagctgaat tttccgatga attaactgtt ctccaagcag
      241 tctttcaagg aaacagcccc ttgatccaaa ctgttcgagc atatgaggaa gcattgatcg
      301 aactagggga aaacggagaa gaccctgatg tgcaaaaacg ttatgctaaa gcagaagaac
      361 aaatgaataa agaagatgct tggactacag ataccaacgc aaagattatt ttgcaaaaat
      421 taggaatcag tgaattagat aaaaaaatca gtactttatc aggtggtcag aaaaaacgag
      481 ttagtctggc gcaagtgttg attgatgaac ccgatttact attactagac gaaccaacaa
      541 accatttaga ttatgaagcg atcgagtggt tggaaaacta tttgaaacaa taccgtggcg
      601 cactattgat ggttacccac gatcgttatt ttctagatag agtagcaaac cgaatcttcg
      661 aactttcatt tggaaaatta tacgagtata aaggaaatta tgaagcttac gtcttagaaa
      721 aagcagaacg tgatcgtgta gaagtagaac aagaagaaaa gcgcaagcgg ctttataaac
      781 aggaattagc ttggatgagg gctggcgtac aggcacgtgg caccaagcag caagcacgga
      841 tcaaccgttt cgaagatcta aaggagaact tgtaccaagt aaaccaagaa gatgatttag
      901 agctgaacct agcgacacaa cgtttaggga aaaaagtact ggaaatcaaa gatggcagtt
      961 accgtataaa tgaccaaaca ctgctagaac atttagattt attgattcaa tctcgggaaa
     1021 gactaggtat tactggtaaa aatggtgcgg gaaaatcgac attgcttaat attctagctg
     1081 gcagaattcc cctggatagc ggtacaatgt ctatcggtga aacggttcat cttgcgtatt
     1141 atacacaaga aaatgaagaa atggcaccag ataaacggat gattgcttac ttacaagaag
     1201 ctgctgaaga agcaaaaaca gcagatggca gtcaaatcgg agtagcagaa ttacttgaac
     1261 gatttttatt tccaagattt atgcatggga cactgatagg caaactttca ggcggagaaa
     1321 aacgccggtt atttttgttg aaactgctga ttcagcaacc taatgtttta ttattggatg
     1381 aaccgaccaa tgatttggac atagcaacat tgacgatttt ggaagattat tttagaagtt
     1441 ttccaggtgc tgtgatcact gtttcccatg accgttattt cttggacaag gtagcagata
     1501 agttattagt attccaagga aacggaaaac aagaacttta ttacggaaac atgtccagtt
     1561 atttactgaa gcaaaaagag acccagcagc ctgctgaaaa agcgaaacca aaaatacaga
     1621 gcaaggaacc tgctgaaaag aagaaattat cttacatgga acaaaaagaa tgggaaacga
     1681 ttgaagatga gattgcagaa cttgaagaaa aaatctcatt gctccaagaa gagatgaatc
     1741 atcaaggaga taatttcact cgattacaag aattgcaaaa cgacgtatct gaaacagaag
     1801 cacaacttga agaaaaaatg gcacggtggg aatacttgag tgaatgggta gaagattagg
     1861 aggaaaaagg atggaacaag cgtatcttga cttaggaaga aaattgttgg aagaagggca
     1921 tcgtaaagaa gacagaacag gcacaggcac attaagctta ttcggatacc aaatgcggtt
     1981 tgatctgcaa aaagggtttc ctttgttaac aacgaaacga gtaccttttg gattgatcaa
     2041 aagcgaattg ctttggtttt taaaaggaga tacgaatatc cgctatctat tacaaaataa
     2101 aaaccatatt tgggatgaat gggcatttga acgctacatc aaaagtccag actataatgg
     2161 accagatatg actgattttg gccatagatg tttgacagat cctgaattca atgaagaata
     2221 taaaaagcag agcaagcttt tttgcgagaa gatcctaacc gatgattcct ttgctgaaac
     2281 atacggcgat cttggacaca tctacggcta tcaatggcgt cactgggaaa caaaagacgg
     2341 tggctttatc gatcaaatca aacaagtgat cgaagcaatc aaaaagactc ctgattctag
     2401 aagattgatc gtttctgcat ggaatccgga agatgttcct agcatggctt tgcctccttg
     2461 tcatacgatg tttcaatttt atgttcaaga gggacggcta agctgccaat tgtatcaacg
     2521 cagtggggat gtgtttctag gcgttccgtt caacattgca agttatgcgt tgctgactca
     2581 cctaattgca catgaaacag gtttagcggt tggcgaattt gttcacacat taggagatgc
     2641 tcatctttat atcaatcata tcgaacaaat gaaagaacaa ttgagccgag aaatacgcgc
     2701 atttccgact ttagttttga atcaggaaaa gcagtcagta tttgattttg agatggaaga
     2761 tatccaatta gaaggatatg acccacatcc ggcgatcaaa gctcctatcg ctgtttagaa
     2821 tcagaaagga tgagaaaatg ttagctgcaa tttgggcaca ggatgaaaac ggattgattg
     2881 gaaaagaaga ccgtcttcct tggcgtttgc caaatgatct gaaattcttc aaacaaatga
     2941 cagaagcaaa tacactagtg atgggacgaa aaacattcga agggatgggt agccgtccgt
     3001 tgccgaatcg tcagacgatt gttttgacga gagattcttc ctataaagca gaaggcgtgc
     3061 atgtcatgca tagtgtggaa gacgtgcttg ctctggaaaa agaaacagac ggtatctttt
     3121 tcatcgctgg agggtcagct gtttatcaag aatttctgcc attttgtacg atattatacc
     3181 gtacagtcat ccatcatgta ttcgatggag atgcttattt tccacctgtt gactggtctg
     3241 attggtcact gatcaatact agtcaaggag aaatggatga aaaaaatcgt tatccgcatc
     3301 aatttgaaac gtatcagcgt aatgagaatc ctgtaaaaag cgggacaggc gaattgacga
     3361 tataaaaaag ctatggatag actagctgtt atttagagct gtcccatcca tagctttatt
     3421 ttttttatta agtaaagaat aaaacagaga agtacataaa acctgcacct aacataacaa
     3481 acaaatgcca aacaacatgc atatagcgga tagaattcaa gctataaaag aatgcgccta
     3541 tcgtgtaaga aagcccgcct gctaccatca aaataacacc agtcattcca agagagtgat
     3601 aaagaggaac agcagccacg acacagagcc accccataaa aatatagatg atcgtagata
     3661 cttttgatac tctctcccgt ttatgcaacg tcaacgcttt atatataatg ccaagaatcg
     3721 caaacaacca gattaataca aataaagtcc aacctagc
//
LOCUS       DACDLM010000243         3202 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.guided.155, whole genome shotgun sequence.
ACCESSION   DACDLM010000243 DACDLM010000000
VERSION     DACDLM010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3202
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.guided.155"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            complement(<1..164)
                     /locus_tag="IV356_003103"
     CDS             complement(<1..164)
                     /locus_tag="IV356_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAP9016685.1"
                     /translation="MKYILSFCTPKLNYLLAYIRLYSGVLHLRDSVRVSEKEKIKVTE
                     MYTSINGELC"
     gene            394..891
                     /gene="dfrG"
                     /locus_tag="IV356_003104"
     CDS             394..891
                     /gene="dfrG"
                     /locus_tag="IV356_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HAP9016686.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(963..2915)
                     /locus_tag="IV356_003105"
     CDS             complement(963..2915)
                     /locus_tag="IV356_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HAP9016687.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2922..3158)
                     /locus_tag="IV356_003106"
     CDS             complement(2922..3158)
                     /locus_tag="IV356_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP9016688.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
BASE COUNT          984 a          553 c          533 g         1132 t
ORIGIN      
        1 ttacataatt caccatttat tgaagtatac atttctgtaa cttttatttt ttctttttct
       61 gatactctaa ccgaatctcg taaatgtagt actccactat aaaggcgtat atatgcaagt
      121 aagtagttca gttttggagt acaaaatgac aaaatgtact tcaaaatgga ctactttttt
      181 cattttaact tacataccaa attacataca aaatgattta taaaatgcaa ttgaaaatga
      241 taattgaatg aaaatttgtg attttgtggt attatgataa tataacttat agaaaaaatt
      301 gcttattcaa ctaacgggca ggataatgag aaaaggtttt ttgatagaaa taagaaatta
      361 gatggtaaat tagttaaaaa ggctgtgtta taaatgaaag tttctttgat tgctgcgatg
      421 gataagaata gagtgattgg caaagagaat gacattcctt ggaggattcc caaggactgg
      481 gaatatgtta aaaatactac aaagggacat ccgataatat taggtaggaa gaaccttgaa
      541 tcaatcggaa gagccttacc tgacagaaga aatattattc tgacgagaga taaggggttt
      601 acctttaatg gttgtgaaat tgttcattca atagaagatg tttttgagtt atgtaaaaac
      661 gaagaagaaa tttttatttt cggaggagaa cagatttata atttgttttt cccttatgtt
      721 gagaaaatgt acatcacaaa aatacatcat gaattcgaag gagatacttt ttttccagaa
      781 gtgaattatg aggaatggaa tgaggtattt gcccaaaaag ggataaagaa tgataaaaat
      841 ccgtataact actattttca tgtatatgaa agaaaaaact tattgagtta acgggtgcgt
      901 taattgaaga agaacagtaa agataaagca caagagcttg ggattactcc aagctctttt
      961 tgtcatttga aataaattat atctttccaa tcaaattgtt tatctgtaat ccctaatctt
     1021 tgagcaggtg tcaaaacctt tttatccgct gatttaaaag ggcgacaaaa gttgtagtaa
     1081 gttcttagaa ttgtaatcgc aaattgagca tacttcggat tgaagttagc gtaaatatag
     1141 ctcttcttat caccacgagc tgttgttaat ggtctttcaa gagatgatat ataacgtctt
     1201 atctgttgaa taaagctatt ggtcgaatgg tcattaacat ttaatagcat ctttgcgatt
     1261 tcgtttggtt ccagagcaga taaatccgtt ctacaatcaa ctgaataaaa tcctttatcc
     1321 ttagtggcta atggatgttt gatagggtta tcggcatatt tgcgatatct ttctccatct
     1381 ttactaatag cctcttcgtg gaattgatga cttgttagta attcagttag ataatgagat
     1441 gccaaagtcc gtagaaactt tgttttgaat cctctgatat ctccccaatc gagcagttct
     1501 gcttttgctt gtccgaattc ttttaagcat tgttttctgc ttttcgtctt gttaacttgg
     1561 caaataaaat gatgtgcatc gctcaacctt aattctttcg tgaatactct ataaaaggcg
     1621 tttctaatag agaagtcatc atcactaatc attcgccatt cgtcggcatt aaccatttgt
     1681 ttaattaacc aatagtgagc agttgtagta taaggagcat caacatttaa accatcgaca
     1741 aatctactcc tattagtaat tttccctaat tcgtgaagat aagcattcct attttcgcta
     1801 tcgttagcgg atggttcttg tggataataa gaccaatcta acctatcatt tttacgacta
     1861 aaagtattga gatggtcttc tttgaatttt cttgtatctt catttaattc atccattgaa
     1921 atattccaat cataggcaac atcagaacgg aacacatatc ttgataagac ctcagcagat
     1981 acaactatat acgtttgcat attaaggtct tcaaaccccg tatatttctt tgaaccttgt
     2041 cctttcttac ggacgttatt taggtagtag tgcatcttgt ccgtattaag ccacatctcg
     2101 ttaaatttct ttgtttgaag gggttgtgtc tcatatcgtt ctaaaaactc caaacaacgc
     2161 ctatacagcc actccagctt atgatagtag gttccaactc caattcctaa aatatcacaa
     2221 gtacgactga ctgaaaccct tccaacaacc atcttagcga acattggaag aatggtgttc
     2281 ttttgttggt gataagtagt ggtttcttct ctttttggta gaacattagt gaacttctta
     2341 cacgccttac attgatagcg ttgagatttg cccctacttt tccccctttt gtaaaattgc
     2401 ttcggctcat tgaatggggt tgattcttct tccgagcagc cttctttatg aaattgataa
     2461 tctggctcaa catcttggat gctattgatt tctataaggc gtttaatttc ttcaacaaca
     2521 gaccaattag ataaaggggt tactgtacag ttttgcgata cacctctgcc aataggattg
     2581 tcattgcagt acataccttt atgaccttta tctttggaac taccagtcat tttatatcga
     2641 cttggtttcc cttttacatc tttgaatttg tgctgttctt tcccaaaatt acaacaaaac
     2701 ggattgatgc agtaattata ttgaatggga tattcagaac cgttccattt aaaagacgtt
     2761 ggcaagaaca acattttgtt ataccttgtt gcaaatcgtt ttggagttaa taaatcatat
     2821 tgtttagccc tatcttttaa ttcttcgttt gaaatcggaa ttttaacatc tacaatttca
     2881 tcttccttcg tggctaatct tttaagcttg gtcattgtct atcaacccac tctatctttg
     2941 atacccattt tttcaacaat ccgcttatta cttcgcttgt tggcaatcca ttcaataaac
     3001 ttcttatcgt ctaaaatgtt caataagaat tcatccactg cttcgctttc agtacgctct
     3061 gcatattcag cgtattgctt aactatcacc cttacttgct ctgatatttc ccaatccaca
     3121 gacttagcgt tcttattttt tggctcaaga aattgcatag gaaaatgcac ccctttttgc
     3181 ttagtaaatt gtaaccattt ta
//
LOCUS       DACDLM010000244         3026 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.guided.157, whole genome shotgun sequence.
ACCESSION   DACDLM010000244 DACDLM010000000
VERSION     DACDLM010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3026
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.guided.157"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            47..1018
                     /locus_tag="IV356_003107"
     CDS             47..1018
                     /locus_tag="IV356_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HAP9016689.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVGHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTARGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            1011..2039
                     /gene="vanB"
                     /locus_tag="IV356_003108"
     CDS             1011..2039
                     /gene="vanB"
                     /locus_tag="IV356_003108"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HAP9016690.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKSAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQIIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVHADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTMPGFTSYSRYPRMVAAAGITLPALIDS
                     LITLALKR"
     gene            2045..2653
                     /locus_tag="IV356_003109"
     CDS             2045..2653
                     /locus_tag="IV356_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HAP9016691.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
BASE COUNT          814 a          635 c          828 g          749 t
ORIGIN      
        1 gaataaaaac tattagacaa atgatatttt acgaggagga gaaccaatga gaaaaagtgt
       61 gggcattact gtttttggat gcgaacagga tgaggcaaat gctttccgcg ctttatcgcc
      121 ggattttcat attatcccta cgctgattag cgatgcgata tcggcagaca acgcaaaatt
      181 ggccgctggc aatcaatgcg ttagcgtagg ccataagtcc gaggtttccg aggcgacaat
      241 tcttgcgctg agaaaggtcg gggtaaaata catttctacc cgcagcatcg gctgcgatca
      301 cattgatacg actgccgccg agagaatggg aatctcggtt ggcacggttg cgtattcgcc
      361 ggacagcgtt gcggattatg ctttgatgct gatgctgatg gccatacggg gtgcaaaacc
      421 caccatgcac gccgtggcgc aacaagattt cagattggat cgtatccggg ggaaagaact
      481 gggggatatg actgtgggag ttattggaac cggccatatc gggcaagcgg tcgtcaaaag
      541 gctgcgggga tttggatgcc atgtgctggc ctatgataac agccgaaaaa tggatgcaga
      601 ttatgtccag cttgatgagc ttctaaaaaa cagcgatatt gttacgctcc atgtgccgct
      661 ttgtgcggat acccgccatc tgatcggtca gaagcaaatt ggagagatga agcaaggcgc
      721 atttttaatc aacaccgcgc gcggagcgct tgtcgatacc ggggcgctgg tggaggcgtt
      781 ggaaagcgga aagctgggtg gtgcggcact ggatgtgttg gagggcgagg atcagtttgt
      841 ttataccgat tgctcgcaga aagtgcttga ccatcccttt ttgtcgcagc ttttaaggat
      901 gccgaatgtg atcatcacac cccatacggc gtactacact gagcgtgtgc tgcaggatac
      961 tacagaaaaa acaatcagga attgtctcaa ttttgaaagg agtttacagc atgaatagaa
     1021 taaaagtcgc aatcatcttc ggcggttgct cggaggaaca tgatgtgtcg gtaaaatccg
     1081 caatagaaat tgctgcgaac attgatacgg aaaaattcga tccgcactac atcggaatta
     1141 caaaaaacgg tgtatggaag ctatgcaaga agccatgtac ggaatgggaa gccgacagtc
     1201 tccccgccat actctccccg gataggaaaa cgcatgggct gcttgtcatg aaagaaagcg
     1261 aatacgaaac acggcgtatt gatgtggctt tcccggtttt gcatggcaaa tgcggggagg
     1321 atggtgcgat acaggggctg tttgtattgt ctggtatccc ctatgtgggc tgtgatattc
     1381 aaagctccgc agcttgcatg gacaaatcac tggcctacat tcttacaaaa aatgcgggca
     1441 tcgccgttcc cgaatttcaa attattgata aaggtgacaa gccggaggcg ggtgcgctta
     1501 cctaccctgt ctttgtgaag ccggcacggt caggttcgtc ctttggcgta accaaagtaa
     1561 acggtacgga agaacttaac gctgcgatag aagcggcagg acaatatgat ggaaaaatct
     1621 taattgagca agcgatttcg ggctgtgagg tcgggtgtgc ggtcatgggg aacgaggatg
     1681 atttgattgt cggcgaagtg gatcaaatcc ggctgagcca cggtatcttc cgcatccatc
     1741 aggaaaacga gccggaaaaa ggctcagaaa atgcgatgat tacagttcac gcagacattc
     1801 cggtcgagga acgaaatcgg gtgcaggaaa cggcaaagaa agtatatcgg gtgcttggat
     1861 gcagagggct tgcccgtgtt gatctttttt tgcaggagga tggcggcatc gttctaaatg
     1921 aggtcaatac catgcccggt tttacatcgt acagccgcta cccacgtatg gtggccgccg
     1981 caggaatcac gcttcctgca ctgattgaca gcctgattac attggcgtta aagaggtgat
     2041 aagtatggaa aatggttttt tgtttttaga tgaaatgttg catggcgtcc gttgggatgc
     2101 caagtacgcc acatgggata acttcacagg aaaaccggtg gatgggtatg aggtgaatcg
     2161 catcatcggc acaaaggccg tggcgtttgc tctgcgcgag gcacaaatcc atgcggctgc
     2221 gcttggctat ggcttgcttt tatgggatgg atatcggcca agaactgcgg tggactgctt
     2281 cctgcgttgg gcagcgcaac cggaggacaa tctcacaaaa gaaaaatttt accccaatat
     2341 agagcgagcc gagttgatta caaagggtta tgtggcctca caatccagcc atagccgtgg
     2401 aagcgcaatt gatcttacgc tctaccacct ggatacaggg gaacttgttt caatgggaag
     2461 taacttcgat tttatggacg aacggtcgca tcatacagca aaagggatag gggatgcaga
     2521 ggcacaaaat cgaagatgct tgcgtaaaat catggaaagc agcggatttc agtcttatcg
     2581 ctttgaatgg tggcactata agttgattga tgagccatac cccgatacct attttaattt
     2641 tgccgtttca taatgaaagt attggttttg tatcagattt tggatttgat aaaatctatg
     2701 ctggtcatgg acaatctttt actggaaagt ggttaaagca tcttttgtaa tacattgcaa
     2761 attatagtat tcaatctgcc cagcggcaga aaagaaaaaa accgctgttg ggcagacctt
     2821 tcccacgccc attttgtatt ttgctggcgg cggttttgag aaatcaaggc cgccgttctt
     2881 ttctggcagc aaaaggtgtg gcggcccata ggaggatgcc gctatgctgt tttgctattg
     2941 ccatgctcta atccacttcc accactcaaa aaagccttgc ccctccatga actgaacccc
     3001 aaaagttgaa ctatttaatg gactgt
//
LOCUS       DACDLM010000245         1247 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.guided.203, whole genome shotgun sequence.
ACCESSION   DACDLM010000245 DACDLM010000000
VERSION     DACDLM010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1247
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.guided.203"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            9..1049
                     /locus_tag="IV356_003110"
     CDS             9..1049
                     /locus_tag="IV356_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAP9016692.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQ
                     LKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSR
                     IDKVRYMFNKIT"
     gene            1147..>1247
                     /locus_tag="IV356_003111"
     CDS             1147..>1247
                     /locus_tag="IV356_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP9016693.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCP"
BASE COUNT          414 a          189 c          247 g          397 t
ORIGIN      
        1 ttacagaaat gtatacttca ataaatggtg aattatgtaa gattgataga gcttattctg
       61 gagaaattgt tattttgcaa aatgagtttt tgaagttaaa tagtgttctt ggagatacaa
      121 aactattgcc acagagaaaa aagattgaaa atccgcaccc tctactacaa acaactgttg
      181 aaccgagtaa acctgaacag agagaaatgt tgcttgatgc ccttttggaa atctcagata
      241 gtgatccgct tctacgatat tacgtggatt ctacgacaca tgaaattata ctttctttct
      301 tagggaaagt acaaatggaa gtgattagtg cactgttgca agaaaagtat catgtggaga
      361 tagaactaaa agagcctaca gtcatttata tggagagacc gttaaaaaat gcagaatata
      421 ccattcacat cgaagtgccg ccaaatcctt tctgggcttc cattggttta tctgtatcac
      481 cgcttccgtt gggaagtgga atgcagtatg agagctcggt ttctcttgga tacttaaatc
      541 aatcatttca aaatgcagtt atggaaggga tacgctatgg ttgcgaacaa ggattatatg
      601 gttggaatgt gacggattgt aaaatctgtt ttaagtacgg tttatactat agccctgtta
      661 gtactccagc agattttcgg atgcttactc ctattgtact ggagcaagcc tttagaaaag
      721 ctggaacaga attgttagag ccatatctta gttttaaagt ttatgcacca caggaatatc
      781 tttcacgggc atataacgat gctcccaaat attgtgcaaa tatcgtaaat actcaactga
      841 aaaataatga ggtcattatt attggagaaa ttcctgctcg atgtattcaa gattatcgca
      901 atgatttaac tttttttaca aatgggctta gtgtttgttt agcagagcta aaaggatatc
      961 aggttaccac tggcgaacct gtttgccaga cccgtcgtct aaatagtcgg atagataaag
     1021 taagatatat gttcaataaa ataacttagt gcgttttatg ttgttatata aatatggttt
     1081 cttattaaat aagatgaaat attctttaat atagatttga attaaagtgg aaaggaggag
     1141 attgttatta taaactacaa gtggatattg tgtcctattt gtggaaataa aacaagacta
     1201 cgaatacgag tggatactat acttaaaaat ttccctttat actgccc
//
LOCUS       DACDLM010000246          865 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate E24005_2016
            SAMN12640534-rid9885113.guided.224, whole genome shotgun sequence.
ACCESSION   DACDLM010000246 DACDLM010000000
VERSION     DACDLM010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12640534
            Sequence Read Archive: SRR10040863
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 22-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000742807.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000742807.1
            Genome Coverage       :: 95x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/22/2020 14:46:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,112
            CDSs (total)                      :: 3,045
            Genes (coding)                    :: 2,963
            CDSs (with protein)               :: 2,963
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 38 of 82
            Pseudo Genes (incomplete)         :: 32 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 10 of 82
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..865
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12640534-rid9885113.guided.224"
                     /isolate="E24005_2016"
                     /isolation_source="environmental"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /lat_lon="32.067224 S 115.830063 E"
                     /collection_date="2016"
                     /collected_by="Murdoch University"
     gene            252..800
                     /gene="aac(6')"
                     /locus_tag="IV356_003112"
     CDS             252..800
                     /gene="aac(6')"
                     /locus_tag="IV356_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAP9016694.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          309 a          127 c          182 g          247 t
ORIGIN      
        1 cataattggt tttttttaaa gcaaaagata atctatatca tgatgaacaa acagagtttt
       61 ttcctccaat tgatggcttt cctgatcttt cctattttga ataaagtgtt tctgtataat
      121 ttttttattt tataagtaag ataaataatg aaagaataga gatactgatt ggtagctaaa
      181 gatttttgag cgagaacatt tcgttttttc aaaaggactg ttagaataag caagaacaag
      241 ggggaagacg tatgataatc agtgaatttg accgtaataa tccagtattg aaagatcagc
      301 tttctgattt actgagactg acttggccgg aagaatatgg agacagctcg gcagaagaag
      361 tagaagaaat gatgaatcca gaacgaatcg cggtagcagc ggtagaccaa gatgagttag
      421 taggatttat tggtgcaatc cctcaatacg gtatcacagg ttgggaattg catccattag
      481 ttgtagaaag ctcccgacga aagaaccaaa taggtactcg attagtcaat tacttagaaa
      541 aagaagtagc ttccagagga ggaatcacga tttatttagg tacggatgat ttagaccatg
      601 gaacaacgtt aagtcaaacg gacctgtatg agcatacatt tgataaagtg gcttccatcc
      661 agaaccttcg tgaacatccg tatgaattct atgaaaaatt aggttataaa atcgtaggtg
      721 tcttaccaaa tgcaaatggc tgggacaaac cggatatttg gatggcaaaa acgattattc
      781 ctcgaccaaa ttctcaataa taaaaagagg ttgtgacaga agtaatcagc ttcaagaaat
      841 aagaaggaat ttacgaaaat tactt
//
